LOCUS       DAUGJR010000001       102223 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUGJR010000001 DAUGJR010000000
VERSION     DAUGJR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102223
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.001"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(362..1480)
                     /locus_tag="VH800_000001"
                     /pseudo
     CDS             complement(362..1480)
                     /locus_tag="VH800_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1785..2582
                     /locus_tag="VH800_000002"
     CDS             1785..2582
                     /locus_tag="VH800_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8361109.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKILANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            2586..3410
                     /locus_tag="VH800_000003"
     CDS             2586..3410
                     /locus_tag="VH800_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8361110.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKADADAVTTLTNDESGVAEAVKTFILEEES"
     gene            3410..4960
                     /gene="ftsY"
                     /locus_tag="VH800_000004"
     CDS             3410..4960
                     /gene="ftsY"
                     /locus_tag="VH800_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEQ8361111.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEAVQQEDVSSEGAGSVENGPEAASVNALVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(5014..6381)
                     /locus_tag="VH800_000005"
     CDS             complement(5014..6381)
                     /locus_tag="VH800_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8361112.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFILFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQAEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            6709..7551
                     /locus_tag="VH800_000006"
     CDS             6709..7551
                     /locus_tag="VH800_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEQ8361113.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSQ
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            7553..9415
                     /locus_tag="VH800_000007"
     CDS             7553..9415
                     /locus_tag="VH800_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8361114.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GEVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            9434..10858
                     /locus_tag="VH800_000008"
     CDS             9434..10858
                     /locus_tag="VH800_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8361115.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(10957..11772)
                     /locus_tag="VH800_000009"
     CDS             complement(10957..11772)
                     /locus_tag="VH800_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEQ8361116.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMILSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(11772..12674)
                     /locus_tag="VH800_000010"
     CDS             complement(11772..12674)
                     /locus_tag="VH800_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEQ8361117.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            complement(12822..12977)
                     /locus_tag="VH800_000011"
     CDS             complement(12822..12977)
                     /locus_tag="VH800_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361118.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            13211..15343
                     /locus_tag="VH800_000012"
     CDS             13211..15343
                     /locus_tag="VH800_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEQ8361119.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            15330..15767
                     /locus_tag="VH800_000013"
     CDS             15330..15767
                     /locus_tag="VH800_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEQ8361120.1"
                     /translation="MTLTNYVQEVSLADFGKSLHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            15831..16103
                     /locus_tag="VH800_000014"
     CDS             15831..16103
                     /locus_tag="VH800_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEQ8361121.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            16468..17400
                     /locus_tag="VH800_000015"
     CDS             16468..17400
                     /locus_tag="VH800_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEQ8361122.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            17397..18176
                     /locus_tag="VH800_000016"
     CDS             17397..18176
                     /locus_tag="VH800_000016"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEQ8361123.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            18198..18605
                     /locus_tag="VH800_000017"
     CDS             18198..18605
                     /locus_tag="VH800_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEQ8361124.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            18598..19026
                     /locus_tag="VH800_000018"
     CDS             18598..19026
                     /locus_tag="VH800_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ8361125.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH"
     gene            complement(19185..19469)
                     /locus_tag="VH800_000019"
     CDS             complement(19185..19469)
                     /locus_tag="VH800_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEQ8361126.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM"
     gene            19668..20594
                     /locus_tag="VH800_000020"
     CDS             19668..20594
                     /locus_tag="VH800_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8361127.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            20685..21971
                     /locus_tag="VH800_000021"
     CDS             20685..21971
                     /locus_tag="VH800_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8361128.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTASIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            22181..22393
                     /locus_tag="VH800_000022"
     CDS             22181..22393
                     /locus_tag="VH800_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEQ8361129.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(22490..22630)
                     /locus_tag="VH800_000023"
     CDS             complement(22490..22630)
                     /locus_tag="VH800_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361130.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(22766..24259)
                     /gene="lysS"
                     /locus_tag="VH800_000024"
     CDS             complement(22766..24259)
                     /gene="lysS"
                     /locus_tag="VH800_000024"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEQ8361131.1"
                     /translation="MSNQHIEELNDQQIVRREKMTALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVRGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGAD
                     FWPEMTVEEAIALAKEKQVPLEKHFISVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            24433..25335
                     /locus_tag="VH800_000025"
     CDS             24433..25335
                     /locus_tag="VH800_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8361132.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            complement(25443..26066)
                     /locus_tag="VH800_000026"
     CDS             complement(25443..26066)
                     /locus_tag="VH800_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8361133.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(26407..26886)
                     /locus_tag="VH800_000027"
     CDS             complement(26407..26886)
                     /locus_tag="VH800_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEQ8361134.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            complement(26977..27540)
                     /gene="thiT"
                     /locus_tag="VH800_000028"
     CDS             complement(26977..27540)
                     /gene="thiT"
                     /locus_tag="VH800_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEQ8361135.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMTLSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSNSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     regulatory      complement(27585..27681)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(27809..28657)
                     /locus_tag="VH800_000029"
     CDS             complement(27809..28657)
                     /locus_tag="VH800_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEQ8361136.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPGKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDSV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     gene            28982..29485
                     /locus_tag="VH800_000030"
     CDS             28982..29485
                     /locus_tag="VH800_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8361137.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGCQ
                     AFLVALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            29469..29855
                     /locus_tag="VH800_000031"
     CDS             29469..29855
                     /locus_tag="VH800_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEQ8361138.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQIQTTPSVPKADHHVRLVV
                     KEDTNTVDEKVSFGKGDTVLEVLKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNG
                     KMADKGADQITVKDGDSIEFYQEVFN"
     gene            complement(29901..30380)
                     /locus_tag="VH800_000032"
     CDS             complement(29901..30380)
                     /locus_tag="VH800_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEQ8361139.1"
                     /translation="MPNLYDFTVKAQDGSDISLVDYKEKVVLVVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(30373..32172)
                     /gene="pepF"
                     /locus_tag="VH800_000033"
     CDS             complement(30373..32172)
                     /gene="pepF"
                     /locus_tag="VH800_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8361140.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIREKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKHNPNGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIISYTEDMSHA"
     gene            32331..35129
                     /gene="ppc"
                     /locus_tag="VH800_000034"
     CDS             32331..35129
                     /gene="ppc"
                     /locus_tag="VH800_000034"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEQ8361141.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQDIIAEEVALLKEMLENITRR
                     MIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDELAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLNTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNIIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAERQDVRDVFYEILDEW
                     QLTKNVILAIQDHDALLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            35269..36573
                     /locus_tag="VH800_000035"
     CDS             35269..36573
                     /locus_tag="VH800_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEQ8361142.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            36927..38123
                     /gene="tuf"
                     /locus_tag="VH800_000036"
     CDS             36927..38123
                     /gene="tuf"
                     /locus_tag="VH800_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEQ8361143.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPSSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            38364..39122
                     /locus_tag="VH800_000037"
     CDS             38364..39122
                     /locus_tag="VH800_000037"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEQ8361144.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(39221..40456)
                     /locus_tag="VH800_000038"
     CDS             complement(39221..40456)
                     /locus_tag="VH800_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8361145.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISRPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTRSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(40443..41669)
                     /locus_tag="VH800_000039"
     CDS             complement(40443..41669)
                     /locus_tag="VH800_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEQ8361146.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FIKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLGIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLATGQTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(41669..42478)
                     /gene="yidA"
                     /locus_tag="VH800_000040"
     CDS             complement(41669..42478)
                     /gene="yidA"
                     /locus_tag="VH800_000040"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEQ8361147.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(42934..44235)
                     /locus_tag="VH800_000041"
     CDS             complement(42934..44235)
                     /locus_tag="VH800_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8361148.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEVLFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSQGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMMQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            44317..44703
                     /locus_tag="VH800_000042"
     CDS             44317..44703
                     /locus_tag="VH800_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEQ8361149.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            44934..47615
                     /locus_tag="VH800_000043"
     CDS             44934..47615
                     /locus_tag="VH800_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEQ8361150.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVEFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(47699..48694)
                     /locus_tag="VH800_000044"
     CDS             complement(47699..48694)
                     /locus_tag="VH800_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8361151.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRISESI
                     KATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(48758..50665)
                     /locus_tag="VH800_000045"
     CDS             complement(48758..50665)
                     /locus_tag="VH800_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEQ8361152.1"
                     /translation="MFFAFARFKETVNPDFCRNYLLDYQTDSYADQKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVIDDPEWNFMLNRQTYLQKLILVYLVERDERYL
                     LTAKGFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFNALTKQEESLIL
                     ASLEKQLQFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDVTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSLCLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDLQILILPPGIFLIIDTIQAQGNHCLVSQFILDNHLDVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNSHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(50752..51573)
                     /locus_tag="VH800_000046"
     CDS             complement(50752..51573)
                     /locus_tag="VH800_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8361153.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYNNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA"
     gene            complement(51560..52342)
                     /locus_tag="VH800_000047"
     CDS             complement(51560..52342)
                     /locus_tag="VH800_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8361154.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFAFIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(52361..52849)
                     /locus_tag="VH800_000048"
     CDS             complement(52361..52849)
                     /locus_tag="VH800_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8361155.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKLLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(52885..54084)
                     /locus_tag="VH800_000049"
     CDS             complement(52885..54084)
                     /locus_tag="VH800_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEQ8361156.1"
                     /translation="MARPLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPESREAALKAADKLVQRYQDKGGFIQ
                     AWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKDLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(54084..54521)
                     /locus_tag="VH800_000050"
     CDS             complement(54084..54521)
                     /locus_tag="VH800_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8361157.1"
                     /translation="MIAIIVMGHGHFASGIVSALELIAGKQEKVTAIDFTTEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGATDDELGGI"
     gene            54857..55651
                     /locus_tag="VH800_000051"
     CDS             54857..55651
                     /locus_tag="VH800_000051"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEQ8361158.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGAIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            55676..56317
                     /locus_tag="VH800_000052"
     CDS             55676..56317
                     /locus_tag="VH800_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ8361159.1"
                     /translation="MKIALINENSQAAKNGIIYDALTTVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFQEYFFANAEPSELVTYLKSVLEQ"
     gene            56346..57347
                     /locus_tag="VH800_000053"
     CDS             56346..57347
                     /locus_tag="VH800_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ8361160.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACEAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CISFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRKKADTTTI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNHFKAYAYDRQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLANQRDIQR"
     gene            57352..57987
                     /locus_tag="VH800_000054"
     CDS             57352..57987
                     /locus_tag="VH800_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ8361161.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            58283..58933
                     /locus_tag="VH800_000055"
     CDS             58283..58933
                     /locus_tag="VH800_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEQ8361162.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLEKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            59625..60749
                     /gene="queG"
                     /locus_tag="VH800_000056"
     CDS             59625..60749
                     /gene="queG"
                     /locus_tag="VH800_000056"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEQ8361163.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRIYTERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GKFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF"
     gene            60818..61916
                     /gene="prfB"
                     /locus_tag="VH800_000057"
     CDS             join(60818..60889,60891..61916)
                     /gene="prfB"
                     /locus_tag="VH800_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEQ8361164.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKI
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            61935..62627
                     /gene="ftsE"
                     /locus_tag="VH800_000058"
     CDS             61935..62627
                     /gene="ftsE"
                     /locus_tag="VH800_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEQ8361165.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            62620..63549
                     /locus_tag="VH800_000059"
     CDS             62620..63549
                     /locus_tag="VH800_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361166.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(63859..64557)
                     /locus_tag="VH800_000060"
     CDS             complement(63859..64557)
                     /locus_tag="VH800_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8361167.1"
                     /translation="MPFIFRYSFFNKVLIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTSGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            64725..65489
                     /locus_tag="VH800_000061"
                     /pseudo
     CDS             64725..65489
                     /locus_tag="VH800_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
     gene            65597..68098
                     /locus_tag="VH800_000062"
     CDS             65597..68098
                     /locus_tag="VH800_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEQ8361168.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFAR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            68433..69626
                     /locus_tag="VH800_000063"
     CDS             68433..69626
                     /locus_tag="VH800_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8361169.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            69647..70993
                     /gene="asnS"
                     /locus_tag="VH800_000064"
     CDS             69647..70993
                     /gene="asnS"
                     /locus_tag="VH800_000064"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEQ8361170.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            71407..72297
                     /gene="rapZ"
                     /locus_tag="VH800_000065"
     CDS             71407..72297
                     /gene="rapZ"
                     /locus_tag="VH800_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEQ8361171.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            72294..73271
                     /locus_tag="VH800_000066"
     CDS             72294..73271
                     /locus_tag="VH800_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEQ8361172.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYPGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            73268..74179
                     /gene="whiA"
                     /locus_tag="VH800_000067"
     CDS             73268..74179
                     /gene="whiA"
                     /locus_tag="VH800_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ8361173.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            74312..75709
                     /locus_tag="VH800_000068"
     CDS             74312..75709
                     /locus_tag="VH800_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8361174.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDEHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYSHEHFNPRYAFGSQRDKDRQYNTPRAWIMQKFLNPEIVQDPRSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDTGYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVFTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            75861..77408
                     /locus_tag="VH800_000069"
     CDS             75861..77408
                     /locus_tag="VH800_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEQ8361175.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEADAGEFKYVQFSDHAIAPEKAKHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            77556..78278
                     /locus_tag="VH800_000070"
     CDS             77556..78278
                     /locus_tag="VH800_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8361176.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLTLKELELRDLIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKTPKTEILS
                     FEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEAGLLGIKKGDPVLHIIRKTYNDKNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            78297..79496
                     /locus_tag="VH800_000071"
     CDS             78297..79496
                     /locus_tag="VH800_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEQ8361177.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCNSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQRYLFESVASTDLVAAP
                     DYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(79593..79853)
                     /locus_tag="VH800_000072"
     CDS             complement(79593..79853)
                     /locus_tag="VH800_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEQ8361178.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(79968..80909)
                     /locus_tag="VH800_000073"
     CDS             complement(79968..80909)
                     /locus_tag="VH800_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEQ8361179.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGKCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            81303..81752
                     /locus_tag="VH800_000074"
     CDS             81303..81752
                     /locus_tag="VH800_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEQ8361180.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            81928..82212
                     /locus_tag="VH800_000075"
     CDS             81928..82212
                     /locus_tag="VH800_000075"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEQ8361181.1"
                     /translation="MRLEKIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQHLTGGDIND"
     gene            82205..83467
                     /locus_tag="VH800_000076"
     CDS             82205..83467
                     /locus_tag="VH800_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEQ8361182.1"
                     /translation="MIKSIATLPKPSLKEVLGLVGLALPIGGAVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKNQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCRRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYSALLPSLVAAYVASWTSHALGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFAYLLGWFKPYLSQKLPNPYFRIAFIGALLSICLMIGHV
                     GRYSGLGTNLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            83582..83929
                     /gene="rplS"
                     /locus_tag="VH800_000077"
     CDS             83582..83929
                     /gene="rplS"
                     /locus_tag="VH800_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEQ8361183.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            84176..84247
                     /locus_tag="VH800_000078"
     tRNA            84176..84247
                     /locus_tag="VH800_000078"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:84209..84211,aa:Arg,seq:cct)
     gene            complement(84210..84524)
                     /locus_tag="VH800_000079"
                     /pseudo
     CDS             complement(84210..84524)
                     /locus_tag="VH800_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            84932..85501
                     /locus_tag="VH800_000080"
     CDS             84932..85501
                     /locus_tag="VH800_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEQ8361184.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILGKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            85502..87454
                     /gene="gyrB"
                     /locus_tag="VH800_000081"
     CDS             85502..87454
                     /gene="gyrB"
                     /locus_tag="VH800_000081"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEQ8361185.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFLYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            87822..89546
                     /gene="ezrA"
                     /locus_tag="VH800_000082"
     CDS             87822..89546
                     /gene="ezrA"
                     /locus_tag="VH800_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEQ8361186.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLEHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(89678..90136)
                     /locus_tag="VH800_000083"
     CDS             complement(89678..90136)
                     /locus_tag="VH800_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEQ8361187.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
     gene            90363..91670
                     /gene="eno"
                     /locus_tag="VH800_000084"
     CDS             90363..91670
                     /gene="eno"
                     /locus_tag="VH800_000084"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEQ8361188.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(92152..93181)
                     /locus_tag="VH800_000085"
                     /pseudo
     CDS             complement(92152..93181)
                     /locus_tag="VH800_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(93448..94988)
                     /locus_tag="VH800_000086"
                     /pseudo
     CDS             complement(93448..94988)
                     /locus_tag="VH800_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            95460..101639
                     /locus_tag="VH800_000087"
     CDS             95460..101639
                     /locus_tag="VH800_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ8361189.1"
                     /translation="MFLKHQDVKQKNWRMRKVKKVFVSSCMLLTVGLGVAVPTGFSQS
                     NGVMVVKAAEVPATDLSRQASDSERVDESSLLQKENLSVDSFKLENLNGWEAENDTAG
                     NLGKFKDPDSSGYQNILTSSGKNISVAVAPKGSGKMNIKVTKRSNFQGGYYVGGLRTQ
                     TPVLKLNDVYRYSFTTKKLSGNSSEFKTRVKPVESNNKLGKELVIRVDNKNVSTKHDW
                     LPDISDGTHTVDFTGLDKKLSVAFRFSPRQTSNVVYEFSNINIKNISPASVPAIPSKV
                     LEGTSVLSGTAISSGDTLEKRKSFDGDILRVYKDSKIIARTVIKGNKWDVKLSKPLIA
                     GEKLDFEILHPRSQNVSKKISKQVEAKPFDPASYKEKVIAKLKPVYEATSEKITNDAW
                     LDENAKDLQKQKLEEQYISGKVAISEAGTKQEAIDAAYNKYSSQTDPDSLPSQYKQGN
                     KENEQEKGRQDLIQTRDLTLKAIQEDKWLTEQEKTIQKEEALKAFETGIESVNQTVSL
                     EQLKQRLIVYKASEKDSEKKEYPESIPNQHIPGKEKEVKAAKQEELKKLHDTTLEKIN
                     QDKWLTPDQQAEQLKQAEVTFKKGQEAIKSAQTLTQLETDLADYVSENEGKGNSIPDK
                     YKSGHKDDLVNKAEVKLKEAHEATKQAIEKDPWLSPEQKKAQKEKAKARLDEGLKALK
                     AADSLEILKVTEEAFVDKEKNPDSIPNQHKAGTADQARKQALDSLDKEVQKELESIDN
                     DNTLTTDEKAAAKKKVNDAYDVAKQTAMEANSYEDLTTIKDEFLSNLPHKQGTPLKDQ
                     QSDAIAELEKKQQEIEKAIEGDKTLPRDEKEKQIADSKERLKSDTQKVKDAKNADAIK
                     KAFEEGKVNIPQAHIPGDLNKDKEKLLAELKQKADDTEKAIDVDKTLTEDEKKEQKVK
                     TKAELEKAKTDVKNTQTREELDKKVPELKKAIEDTHVKGNLEGVKNKAIEDLKKAHTE
                     TVAKINGDDTLDKATKEAQVKEADKALAAGKDAITKADDADKVSTAVTEHTPKIKAAH
                     KTGDLKKAQVDANTALDKAAEKERGEINKDATLTTEDKAKQLKEVETALTKAKDNVKA
                     AKTADAINDARDKGVATIDAVHKAGQDLGARKSGQVAKLEEAAKATKDKISADPTLTS
                     KEKEEQSKAVDAELKKAIEAVNAADTADKVDDALGEGVTDIKNQHKSGDSIDARREAH
                     GKELDRVAQETKGAIEKDPTLTTEEKAKQVKDVDAAKERGMAKLNEAKDADALDKAYG
                     EGVTDIKNQHKSGDPVDARRGLHNKSIDEVAQATKDAITADTTLTEAEKETQRGNVDK
                     EATKAKEELAKAKDADALDKAYGDGVTSIKNQHKSGKGLDVRKDEHKKALEAVAKRVT
                     AEIEADPTLTPEVREQQKAEVQKELELATDKIAEAKDADEADKAYGDGVTAIENAHVI
                     GKGIEARKDLAKKDLAEAAAKTKALIIEDKTLTDDQRKEQLLGVDTEYAKGIENIDAA
                     KDAAGVDKAYSDGVRDILAQYKEGQNLNDRRNAAKEFLLKEADKVTKLINDDPTLTHD
                     QKVDQINKVEQAKLDAIKSVDDAQTADAINDALGKGIENINNQYQHGDGVDVRKATAK
                     GDLEKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTAEGINQELGK
                     GITAINKAYRPGEGVKARKEAAKADLEKEAAKVKALITNDPTLTKADKAKQTEAVAKA
                     LKAAIAAVDKATTAEGINQELGKGITAINKAYRPGEGVKARKEAAKADLEREAAKVRE
                     AIANDPTLTKADKAKQTEAVAKALKAAIAAVDKATTAEGINQELGKGITAINKAYRPG
                     EGVEAHKEAAKANLEKVAKETKALISGDRYLSETEKAVQKQAVEQALAKALGQVEAAK
                     TVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAALNEAKQAAIEALKQAAAETLAKIT
                     TDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIASVKEAKDKGITAIRAAYVPNKAV
                     AKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLYSKKKESKD"
     gene            complement(101825..101941)
                     /locus_tag="VH800_000088"
                     /pseudo
     CDS             complement(101825..101941)
                     /locus_tag="VH800_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        31740 a        18129 c        21680 g        30674 t
ORIGIN      
        1 tcatttagaa taataatcac atattgttgt caacgaaacc caccatagtc tataatgaaa
       61 gcctagtagg gatgagctat ataccaacta tctatcaatc cagacgtctc tactaaaaaa
      121 tactccgtct tctatgaaac tagaaacgga gtatttctgt ttgtctatac cactaaatga
      181 acagttatat agaaaggtga ttggatgttt ggaataaaca tcctgaaaaa aatttgagac
      241 cttcttatat cctaaactag aacgaatgtc tagtgaaata aaaaaagcga caccattagg
      301 atgtattttg gactaatgtc aaataagtag acagaaaacc gtgttatttt attacgttaa
      361 actaattttc ttctttctga ttaggggtta gtcctagatt agccgtatgt gggttgtaat
      421 tgttataaaa attctcaatg tattcaaagc agtctaattg aacctgtttg atactttttt
      481 tggttgattt gtctatgctt taaatacttg aaaaatgctt cagttacggc attatcataa
      541 ggatatccag gtttagaaaa agaatgcatg atagtgttgt catcaattat ttttctcaat
      601 tccctggcct taaattgtga cccttggtcg gaatgaaaga gaagtgttcc ttcaatcttt
      661 cttttattaa gagctaattc tagagtgtca catgctaact ttgcatccat acggtgactc
      721 agtttccaag caatacattt tctagaatag agatcaagta ttgcgcagag atagacatat
      781 ttcttatatc caatagaaat ataggtgaag tcagtagacc atacttgatt aggtttgtca
      841 ggattaaatt tctggttgag taagttttga ggatacgttt tttgagtcct tttaagagct
      901 gtttttggct taacggtagc cattttaggg agcgccatat tcttcattag acggtaaatt
      961 cttccttcag agatttttgt gtcgtagtct ctttgaagaa tgactttgat agacttcaca
     1021 ccaagtcttt tgtttgcttt ggtataaatc tcaagtattt gttttctata aatttgatta
     1081 tccaattctc tttttgaggg cttatgtttt agaaatttat agtaagtgga gcgattgaca
     1141 cgtaaaacac gatacaaggt tgttgtgacg tgttcaaagc gtaaccgata aacagcgagg
     1201 agtcttactt taagttttgc atgaatatgg cacttgcttt ttttaggata aggttctcct
     1261 cttcaagctg cgcattacgt ttttgtagct cttgtatttg cttggcagta agtacagaat
     1321 tatcttcgag tttgacttgg gaatactgtt tgatccattt tgcaagcgca gaagcggata
     1381 ccccatagtc tttacagagt tcagaccgag tttttccagt ttgataaagg ttaacaagag
     1441 attgtttgaa ttcttcatca tagcgtttaa ctgttgacat aggctgtcct ttcgtttttg
     1501 tgtcttttaa aacagattgt aacacacaaa gttttgtcta cttttatagt atacatccag
     1561 tggtcattta taaaaataaa aaaagtagca gttcacttca aaaacggtca ggttatcgaa
     1621 atataatctg gctgtttttt acgaatggaa tgaaagctgc tttttatgat ataataagaa
     1681 aaattgaaca gaatgcagaa atgatggggc ttatttaaat cgttaaaaag tgcacaccct
     1741 aaatggcgtt tgcacccccc tagagtaaaa aaaggagaca ttgtatgata aaactaatag
     1801 caacagatat ggatggtact ttcctagctg aagatggtac ttataatcaa gagcaactag
     1861 ctgcgctctt gccaaagtta gccgaaaaag gcattttatt tgcggtttcg agtggccgct
     1921 cgctcttagc cattgatcag ctctttgagc cctttttgga tcagattgct gttattgcag
     1981 aaaatggttc cgtggttcaa taccgtggtg agattctatt tgcagatatg atgaccaaag
     2041 agcagtatac cgaagttgca aaaaagattt tagccaatcc tcactatgta gaaacaggta
     2101 tggttttttc tgggcaaaag gcagcctata ttttaaaagg cgcatcagaa gagtacattc
     2161 aaaaaacaaa acattactat gctaatgtta aggttattaa tggttttgaa gatatggaga
     2221 atgacgccat ttttaaagtt tctaccaact tcacaggcca taccgtctta gaaggaagcg
     2281 attggttgaa tcaagccctc ccttatgcca ctgcagtgac caccggcttt gattccattg
     2341 atattatctt aaaagaggtg aataagggct ttggtatgga gcatctttgt caagccttgg
     2401 gcattaagaa agcagaaacg attgcttttg gggataattt taatgattac cagatgttgg
     2461 agtttgctgg tagggctatt gctacggaaa atgcaagacc tgaaatcaaa gtgatttcag
     2521 accaagtcat tggccactgt aatgacggag cagtactaac gtatttaaaa ggactagtgt
     2581 aactcatgaa tattagaatt ttggcgcttg atttagacgg taccctctac aacactgaaa
     2641 aaattgtcac agatgccaat aaaaaagcct tagcagcggc tagagaaaaa ggggttaagg
     2701 tggttattac cacaggtcgc cctctaaagg ccatcggtaa cttgctagaa gagttggact
     2761 tgcttgacca cgatgactac agtattacct ttaatggggg gttggttcag cgaaatacag
     2821 gggaggtttt ggataagagt tctctcagtt ttgaccaggt ttgccagatt cagcaagctt
     2881 tagaggcggt tggcttacca acagatatta tcagtggtgg ggatgtgtat agcattccaa
     2941 gtaaggacgg taggcattcg cagtaccatc tagctaaccc actgttgacc tttattgagg
     3001 tgacatctgt agcggaacta ccaaaagaca ttacctataa caaaattgtg acagtcaccg
     3061 atccagactt tttggatcag cagattataa agctatcccc aagcttattt gaggattttg
     3121 aagcctttaa atcacgagat attatttttg aaatcatgcc aaaaggcatt gataaagctt
     3181 ttggattaaa cttgctttgt cagcaccttg gccttgacgc tagacatgtc atggctatgg
     3241 gagacgaagc taacgacttt gcgatgttag aatgggcagg acttggagta gctatggcta
     3301 atggtgtttc aggagctaaa gccgatgccg atgccgtgac caccttgacc aatgatgagt
     3361 ctggagttgc agaagctgtg aagacattta ttttagaaga ggagagttaa tgggattatt
     3421 tgatcgttta tttgggaaaa aagaaacccc gaaggtagct gaggaaaagt tagaagaaaa
     3481 tcttttgaca gaaacaactc agaaagagga gctttctgaa aaagccaatg agcaagacaa
     3541 gattgaggcg gttcaacaag aggacgtttc ttcagagggc gcaggttcgg tggaaaatgg
     3601 tcccgaagca gcttcagtaa acgcactggt tgaggaagaa acaggtgaca atagtaatca
     3661 tccatcagaa gataccaatg agtttgctgc cgacaaaaca gaccttaagg taagtgaact
     3721 tagtcaatct acggcatcag aaccaaaaga ccttgttgac cagccagttg tggaacagtt
     3781 tccaacaaaa caagcccaag ctgatgcctc aaatgattcg gcgaatgaag aagcagtaga
     3841 cacttcaaaa gagcaatcca gtagccaaca ggttatggaa gactactacc gtcgtaaggc
     3901 tgctcttgaa aaaagccttc aagaaaaagc agcggcaacg gttccagtga tgccagaaga
     3961 agttccacaa gaaaatcagg cctctacctc agcagaagct tctcaaaaca aggcaaccca
     4021 cgataccatt cctgagacag atcaagaaaa atacaagcgt agcttgaaaa aaacgcggac
     4081 tggcttctca gctcgtctga acagtttctt tgccaatttc aggcgagtgg atgaagaatt
     4141 ctttgaagac ttggaagaaa tgctgatctt atcagatgtc ggtgtacatg tggcgacaac
     4201 tttgacagag gagttgcgtt atgaagccaa actggaaaat gcgaaaaaac cagatgcctt
     4261 gaaacgtgtg attgtggaaa aattggtaga tatctatgaa aaagatgggc gttataatga
     4321 agccattaat tatcaagatg gcttgacggt tatgcttttt gtaggtgtta acggggttgg
     4381 taaaacgact tcaatcggga agctggctta ccgttacaaa caagaaggta aaaaagtcat
     4441 gttggtggca gcagatacct tccgagcagg ggctgtggct cagctagtcg aatggggacg
     4501 ccgagtagat gtgccagtca ttactggccc tgaaaaggct gatccagcgt ctgttgtttt
     4561 tgacgggatg gaaaaagctg tggcaaaagg tgtagatatt ctcctgattg acacggctgg
     4621 tcgcctgcaa aacaaagaaa atctcatggc agagctggaa aaaatgggtc gtatcattaa
     4681 gcgcgtgcta ccagatgccc ctcatgaaac gcttttggcc ttagatgcgt caacaggaca
     4741 aaatgcgctt agccaagcca aggaattttc aaaaataaca ccattaacag gtttgatttt
     4801 aacgaaaatt gatggcacgg ccaaaggtgg tgtagtccta gccatccgtc aagaattaga
     4861 cattccagtc aagtttatcg gatttggtga aaaagtggat gatattggag aattccactc
     4921 agaagacttt atgaaaggcc ttttggaagg tatcttataa cagcaaaaac cagtctcgtt
     4981 ttattgaacg agactggttt ttagtatgtc atcttaggct aatccttttt tccctaaatg
     5041 gtaaaacata gcaaagaaaa agataaaatc aagtagagca aaaatagtaa agagaaggta
     5101 gacagactgg acaccgcttg tgaattctgc ttgactattt gctatcagtg atgccatagc
     5161 agttcctaga gcgccagcaa attgctgcat catctgaaaa atggccgtgg catcggcatt
     5221 tttctcggca ggcaattctc gaatagccgt ggctaagcta ttattaaagc ccatgttacg
     5281 cccaaacgtg aataaaatat ataaaagagt gaatggtaaa agcataaaat gtcttgtttg
     5341 aagtgtcata ataatcaatg ataaactaaa taaggcattt cctaaataaa gcgaaagtct
     5401 tgctcctttt tgatcataaa gtttaccaaa agcaggtgct agtagagctc cgagtaaggt
     5461 accaggtagt aacaccatac cagcttgaga actattagca atcttttcca tgacaataaa
     5521 gtttggcgtt agaaaattta tgcctaaatt aatcagctgg aagacaaaaa agggaatcag
     5581 gccaaaggtt agagagggaa ttttgagaat gcgaatatca agaaagggtt gcttagctgt
     5641 gagattcttg tagaggaaga ggataaagct gagaataaaa agccctaagt aatacaaatt
     5701 aacactgccg ttttctagac tagtaatagc taataaggca gaagttaagc taatcgatag
     5761 tgcaataaat gccaaccagt caaagggtac tttttcgctt actggagaat cttcgaggta
     5821 ataataagct agaatacctg caatcagtgg tacagggagt atacagataa aaatccattg
     5881 ccaactaaaa tggctaatca taaagccccc ataagtaggc ccaaaagcag gtgctaagct
     5941 aataataaga ccagcaaatc ccataaatag acctacctta tgcattggga cacgctctaa
     6001 aataatatta aacatctgag gcattaccag accagtacca atgccttgaa aaatgcgggc
     6061 tagcaacatg atcgcaaagg actgggtcag aacggccaag atggtgccaa atgtaaaaag
     6121 acctgtggcc ataaaaaaga ggggtctttc ccgcacattt tttttcagtg tagccgaagt
     6181 ggtcatcata atcgccactg ctagtaaata aatggtcgtc atccattgca agctatttaa
     6241 gggtaactga tagactgaca tcagtgtcgg gaaggtgaca ttcatactgg tttcagacaa
     6301 aattcctgaa aaaccaatga gtgctatggc gataatcgcc ataattgttt gttttgaaac
     6361 ggtttgttga tgatgtgaca tgataactcc tttatctaat cgattgttat tgtatcatat
     6421 aatcttaaaa ttgtcagaaa ctcttttttg ctaaatcaat agatacgaat aacaatagtt
     6481 gctctttcag agaatttttt gaaaacgctt gacagaatct taaagagatg ataacattaa
     6541 agcgttctca gatgtgatta cttcaggtaa gcaggctaga gacataacaa tcagaatatt
     6601 aaaggatgtt atcacagttt tgtgagcagg gacctatttg aaaagtgctt tttagcgagc
     6661 ttttggatag gtcatttttt attgtgatac taaaggacta ggacttttat gttgattaaa
     6721 cgcgttttaa accataatgc ggcgatttcg accaaccatc aaggattaga tattttattg
     6781 atgggaaaag ggattgcctt tggaaaaaaa gttggagata gtattgagct taatgctatc
     6841 gaaacatcat ttgttttaaa aaatagtgac aatatgaatc gcttcacaga gttatttatt
     6901 acggtgccac aagaagttgt tgcttgctca gagagaatta tcaatctagg taaaattaaa
     6961 ttaggcaaaa ccttagatga aattctctat attaatttaa cggatcatat tcactctgct
     7021 attgaaaggc atgagcaagg aatgttgatt cataacccac tacggtggga aattcaacgc
     7081 tattatcctg atgaatatag tctaggggta aaagccttag agctaattga gcgtaatcta
     7141 ggagtcactc tagctattga tgaagcagct tttattgcca tgcattttgt caatgctagt
     7201 ttggacactc cttttaagga gccacatcgc ctgacggaga ttgtttctta tattgagcaa
     7261 aaaatcaaaa cagacttcaa aacagaattg gatgacacat ccatcgatta ttaccgcttt
     7321 atgacccata ttaaattatt tgctcaacgt gtgttatcac agatgtctta cgatgatgat
     7381 gatgcggaac tgcttttagt ggtgaaaacg aaatacccta aagaatatcg gtgcgtctta
     7441 gatattagtg aggagataaa aaagcggtac aactaccacc ttaattcaag cgaacttttg
     7501 tatttgacgg ttcatgttaa acgtttagtg aaacatttaa aggagactta atatgacgta
     7561 tcaagaaact gccaaggcta ttttagcggc ggttggtggc aaaacaaata ttcaacgtgt
     7621 gacacactgt gtaacacgtc tacgcttagt actgaaaaat gatgagaaag ttaaagatca
     7681 gcaagtcaaa gccatttcaa atgtgattgg cgtgatgcgc aaaaacggcc agtaccaaat
     7741 tatcttgggc aatgatgtca ataattatta ccaagccttt ttaagcctag ggcattttga
     7801 caatcaagat gaagatcatt cttcaaaagc gaaaggaagt atccttgagc gcttgattga
     7861 aaccattgct ggcgtgatta caccgctgat tccagccctt cttggtggtg gaatgctcaa
     7921 agtggtggga atcttgcttc ctatgcttgg cttagcgagt gcggactctc aaaccgttgc
     7981 ctttattaac ttctttggcg atgcggctta ttattttatg cctgtcatga ttgcctattc
     8041 agcagcggcg cgctttaagg tgacacctgt tttagcagcg acgatcgcag ggattttatt
     8101 gcatcctgcc tttgttgcaa tggtagcaga aggtaaacca ttgactttat ttggagcacc
     8161 agtcactcct gctagctatg gctcatctgt tattcccatt ttgatgatgg tttacttgat
     8221 gcaatacatt gaaaaatggg tcaatcgctt ggtgccaagc gtgatgaaaa gcttcttaca
     8281 gccaacctta atcattttga tttctggctt tttggcttta gtggttgtag gtcctcttgg
     8341 tgtgattatt ggtcaagggt tatctaatac catgctcgct atttatcatg tggctccgtg
     8401 gctagcactt gctattttgg gagcgattat gccgcttgtt gtcatgacgg ggatgcactg
     8461 ggcttttgca ccaatctttt tggccgcttc ggtcgcaaca ccagatgtct tgattttacc
     8521 agcaatgttg gcttctaatt tggctcaagg agccgcatct ttggctgttg cctttaaaac
     8581 aaagcagaaa caaacacgtc aagttgccct tgccgcgggg atttcagctt tgctggcagg
     8641 tatcacggaa ccggcacttt atggggtcac actgaaattt aaaaagccac tctatgcagc
     8701 catgatttca ggtggtctgg ttggagcctt tattggtttt gtcaatattg cttcttatac
     8761 ctttgtcgta ccttctatta ttggtttacc acagtacatc aacccatcag gcggagctaa
     8821 ttttacaaat gctttgattg ccggaactgc gacgattgtg ttagccttca gtttgacttg
     8881 gttcatggga attgatgaag agtccccaaa gcaagtgagt gttgcagcag atatgtcaca
     8941 agttaagagc ggcttgtcaa ccaaacaaac gttgtatgct ccaatgacag gtgagatgct
     9001 ttttctatca gaagttcctg atgaaacctt ttcttccaag ttattaggag aaggatttgc
     9061 catattacca agcgaaggtg aggtctatgc cccctttgat ggtgaagtca tcactttctt
     9121 tccaaccaag catgctgttg ccttaaaaaa cacacgtggt gtggaagtct tgattcatgt
     9181 cggtattgat acggttgagt taaaagggca aggtttcgag cagttagtgt ctgttggcga
     9241 tgtcgtgaaa cgaggccagg cacttctaaa aatggatatt gatttcatta cttcaaaagg
     9301 ctattcactc atcagtcctg tggtcgtgac caattcggct gagcagttgg agattattat
     9361 tcaagatgac aaaaaaatgg tgactaaaga ggacgctttg ttagtcattt tataacctaa
     9421 aaggagaggg agaatgggaa tttttccaaa agatttctta tggggcggcg cagtagctgc
     9481 caaccaagtg gaaggagcat ttgaggcaga cgcaaaaggt ttgtccgtac aagatgttct
     9541 accaaatggt ggactaggag aatggacaga tagtcctacc agcgataatt taactttaga
     9601 ggcgattgat ttttaccacc gctacaaaga agacattgct ctttttgccg agatgggctt
     9661 taaagtcttt cgaacgtcta ttgcttggtc tcgtattttt ccaaatggtg acgatgacca
     9721 gcccaatgaa gcaggtttgc aattttatga tgacttattc gatgaattgt tgaactatgg
     9781 catcgaaccc ttagtgacct tgtcgcatta tgagacacct ctgcatttgg ccaaagccta
     9841 taatggttgg acagatagac gtctgattgg cttttttgag cgctttgctc agacagtcat
     9901 ggaacgctat aaggacaaag tcaaatactg gttgaccttt aacgaagtca actcgatttt
     9961 acacatgccc tttaccagtg gtggcatcat gacagaaaaa gaaaagctga gcctgcaaga
    10021 tttataccaa gctattcatc atgaattggt agcatctgct agtgtcacaa agctagcgca
    10081 tgaaatcaat cctgatgtta aagttgggtg tatgattttg gcgatgcctg cttacccaat
    10141 gacctctgat cctcgtgata tacttgctgc gcatgcattt gaaaatctta atctcttatt
    10201 ttcagatatt catgtgagag gcaagtatcc ttcatatatt aagtcgtatt ttaaagaaaa
    10261 tgggattgag attgtttttg aagacggaga caaggaatta ttagcggaac atacggttga
    10321 ttttctatcc tttagctatt acatgagtgt cacacaagcc cacaatcctg aagcttacac
    10381 atctggtcag ggaaatattc taggtggttt gtccaatcca tatttagaat cttcggagtg
    10441 gggttggcag atagacccaa ttggtctgcg attggtcttg aatcagtact atgaccgcta
    10501 ccagattcct ttgtttattg ttgaaaatgg cttaggtgca aaggatcagc tggtgcaaac
    10561 cgcagatggc agcatgacgg ttcacgatga ttatcgcatt gactacatga gtcagcatct
    10621 cgtacaagtt gccaaagcga ttgaagatgg cgttgaggtc atgggttaca cttcttgggg
    10681 ctgtattgat tgtgtctcta tgtcaacagc ccaattaagt aaacgctacg gttttattta
    10741 tgttgaccga aatgatgatg gtactggtca actcacacgc tataagaaaa aatcatttga
    10801 ttggtaccga caagtcattc aaaccaatgg acgttacctt gaggataatt tttcctaaat
    10861 aggtcttgtt taagatggtg actctgttcc tatgctaact gataaaactc aaaaagcatt
    10921 tgttttgata aaaaacaagt gcttttttat tagtctttaa aaaacgcggt aaacataagg
    10981 attattaggt tctttggttt gatgaacctc agcaagttga aggacaggta gatgttgttc
    11041 taagttttta tcatattcca tatgaaggcg acctttaact gttagccatg tgttgttagg
    11101 gtagctggtt tgattacctg tggtcaaaag tccgtacact cctgagtcgg caatacagtg
    11161 aataatgccg aagcggaaaa ggaattggta gttgtcatgg cccggttcgt tataaacaaa
    11221 gccagtgtat tggatgtcac gatcaagaaa ctcatctggg tagagataga tcaattccat
    11281 cacttccata taattttcag tggtaatggt gaccggtttc ttgcctttat atttatggag
    11341 ttcttgacgc atctcctttt ggtaggcaga ctttgtaaag taaaggctgg tatcaggttt
    11401 gaggtattga atggtggtac cgtcatcact gactcccgtt ttagaggctc ccgcagccaa
    11461 tgggaaagta tagcctttag cagaaaccgt ggtggaatct aaggtcacgg tcggcacaag
    11521 gagaccaatc aaaacaggaa agaccaagat aaaaggactc gtcagccttg cgatttttcc
    11581 tgttaaatgg ctatgtacct taatgttttt catccaggta tagagttgaa caagagctaa
    11641 aatgaaagat aaaatcatgg aaatataagc aaggtaagaa taccgaacat tgatgtactg
    11701 atccagtttg ccagacagct ggagatacat ggttagttca aaatagccag ctaaaattaa
    11761 aaagcgaatc attagagcac ccccacaagt aaacaataaa cggcaatcat aagaacggat
    11821 acgccgataa attggacaat gaagcgtcct ttaaaagcct ttaccatcat cataaggttt
    11881 ttaatatcca ccataggacc aattaaaaga aaggcaagaa ctggagccac tccaaaggtg
    11941 gataataagg aagctccgat aaaggcatcg gcttcactac ataatgatag aatgaaagcc
    12001 atcagcatca tgatcaaaat ggctgtcaag ggattgtgcc caatcgttgt caacacacga
    12061 gttgggacat atatttgcat ggcagaggca atcaaggttc caaatacgag atacctaccg
    12121 gtgtcgaaga attcatcaat agcatgtacc agtgctagat aaatgcgttt tggcaagctt
    12181 tcatgagaat aatcatgaaa atgcacgggt tgagcattat ccttgagaat gttatcatct
    12241 acaataaaag ctaacattac cccaagtgta atggctacta gtgcagcacc gaccaagcga
    12301 agtatcagaa agcgcaaaga attcccaaaa gcagaataag tagcgaacaa aacaatagga
    12361 ttaatgatag gcgctgttgc cagaaaaggg acggccgtat aactaggcac ctttttttcc
    12421 aaaaagcggt tgatgatggg aataatcccg cattcacaag aaggaaaaac aaatccaaca
    12481 aaggttccaa acagaatgcg caagcatttt tgcttaggta ggtatttttg aaccaattct
    12541 ggcgttacaa agacttcaat acaaccagat aaaatagttc ctaggagcac aaaaggaaga
    12601 gcttcaatga taatggacat aaaaatcgca aaccattgca agacactggg aggaaggttg
    12661 gaaaagagtg acattcacca tatcctttct agatgataaa agaggaggct gaaacacgaa
    12721 tgttcagcct cgactgatac gttttgttag cctgatcgct aaaaatctct caactcagtt
    12781 taaacgaatg gacgatatgt taagagaatg agacaaacta gctatggttt gcttggtttt
    12841 gtttgttctg tcgttttttc tttggtcgct agtttaccat cagtattgac ttccaaaggc
    12901 ttatcaaaac tagggattga tgcaaagcct gctagcattt tttcaagttc atcatttttt
    12961 ttatgggtaa ttgccatatc tatgaccttc tttcattcaa gataagtcta ttatactatc
    13021 atttgagaac aatgccaaag cggaagtgtt gtttacttct ttctttttta aaattaggta
    13081 ttgttattta gggtttcgtc agttatttac taaaagtagc tttttttgat tctttacgca
    13141 actttatatt aggacaatgt ttcgctatca ttttttgcat taacatggtt tgtgttataa
    13201 tagcaatatt atggaaaata acaataatca caacattgca gaggctttgt cagttagtct
    13261 ccatcaaatt gaacaggtgc ttgccctaac agcacaaggc aataccattc cctttattgc
    13321 acgttaccgt aaagaagtaa caggaaatct agatgaagtg gtgattaagt ccattattga
    13381 tatggataag tctctcacta ccctgaatga gcgcaaagca accattctcg ctaaaattga
    13441 ggaacaggga aaactgacag atcagttacg aacgagtatt gaagcaaccg agaaactcgc
    13501 tgatttggaa gagttgtacc tgccttataa ggaaaaacgc cgtacaaaag cgacgattgc
    13561 gcgtgaagca ggcttgttcc cattagcacg tttgatttta caaaatgcgc aaaaccttga
    13621 aacagcagca gaaccctttg tcacagaagg atttgccagc ccacaagaag ctctagcagg
    13681 agctgtggac atccttgtgg aggccatgtc agaagatgct aaattacgct cttggaccta
    13741 caatgagatt tggcagtaca gccgcttagt atcaacgctt aaagatgagc agttggatga
    13801 gaaaaaggtt ttccaaatct attacgattt ttctgaccaa gtgtctaaca tgcaaggata
    13861 tcgtacttta gcccttaacc gtggcgaaaa gttaggcatc ttaaaagtgt cttttgagca
    13921 taacttggag aaaatgcaac gctttttcag tgtgcggttc aaagaaacca acccttatat
    13981 tgaagaggtc atcaatcaga ccatcaaaaa gaaaattgtt ccagctatgg aaagacgggt
    14041 tcgttcagaa ctcagtgatg ccgcagaaga tggggctatc cacctctttt ctgaaaatct
    14101 ccgtcatctt ttgttagtgt ctcctttaaa agggaaaatg gttcttgggt ttgaccctgc
    14161 ctttcgaaca ggtgcaaaat tggctatcgt tgatcagact ggaaaattgt tgactactca
    14221 ggttatttat cccgtagcac cagctagcca aacgaagatt caagcagcta aagaaacact
    14281 gactcagctc attgagactt accagattga tattattgcc attggaaacg gaacagccag
    14341 tcgggaaagt gaagcctttg tagcagacgt tttgaaagat ttcccaaata cgtcctatgt
    14401 catcgttaac gaaagcggtg cttctgttta ttcagcgtca gagttagccc gccatgagtt
    14461 tccagacctc acagtggaga agcgctctgc tatttctatt gctcgtcgct tgcaagaccc
    14521 actcgcagaa ttggttaaaa ttgatcctaa atctattggc gtcggtcagt accagcacga
    14581 tgtgagtcag aaaaagttga gtgagaatct tggttttgtt gtggatactg tggttaacca
    14641 agtcggtgtt aatgtgaaca cggctagtcc atctttatta gcacatgtgt caggtttgaa
    14701 caaaacgatt tcagaaaata ttgtcaaata ccgcgaagaa aatggagcac tgacatcacg
    14761 cgctgacatc aaaaaagtgc cgcgtttagg agccaaggcg tttgagcaag cagcaggttt
    14821 tctcagaatt ccaggagcca aaaatatttt agacaacaca ggagttcacc ccgagtccta
    14881 cccagcagtc aaagaactct ttaaggtact tggtattcag gacttggacg acgctgccaa
    14941 ggcaacttta gcagcagttc aagttcccca aatggcagaa acattggcta ttgggcagga
    15001 aacccttaaa gatatcattg ctgatctcct taaaccgggt cgtgaccttc gtgatgactt
    15061 tgaagcacca atcttacgtc aagatatcct tgatttgaaa gatttggaaa ttggccagaa
    15121 gcttgaagga actgtgagaa acgtcgttga ctttggtgct tttgtagaca ttggtgttca
    15181 tgaagatggg cttattcaca tttctgaaat gagcaaaacc tttgtcaacc accctagtca
    15241 agttgtttca gtgggtgact tggtaactgt ttgggtctct aagattgact tggaccgcca
    15301 caaggtcaat ctcagcctat tgccaccgcg tgacactcac taattatgtc caagaagttt
    15361 ccctggctga ttttggcaaa tcacttcacc acaaggctta ttggaacaag cgcctaaaaa
    15421 caactggcgg tcgctttttt ccaaaagatg gtcatttgga ttttaaccct aggatgcttg
    15481 aggagcacgg tgagcttatt tttcggaaaa ttgttcgcca tgagctctgc cattaccatc
    15541 tttattttga aggaagaggg taccatcata aagataggga tttcaaagat ctgctagctc
    15601 aagtaaacgg gcttcgttat gtcccaacta gctctaaatc aaagactaat catcattata
    15661 gttgccaaac ctgtgggcag gtttatcaac gaaaaaggcg tatcaatctg gctaaatatg
    15721 tttgtggaaa ttgccacggg aaacttatgg aaaaaaatca gtcgtaagac tggttttatt
    15781 ttgcgaaaaa caatgtaaac tagtatcata gaatgaggag gtaaagaaac gtggaaacta
    15841 aattctataa acagcgaaaa aatcgcttgg ttgcaggtgt tattgctggt ttagcagata
    15901 agtatggttg ggatcttgct ctagcgcgtg tcttagcggc tcttcttatt tacggaactg
    15961 gttttggagt tttgctttat attttgttgg ccatcttctt accttacaag gaagacttgc
    16021 ttgaagaacg ttatggccga ggtcctcgtc gtcgtaaaga cgctgatgtc ttaaatgaag
    16081 aagaagatgg ttggttctgg taaataatca gttaaaatga taattcatca cgtaagagca
    16141 accatgtgat taactgatga taataaaatg ttttgatatg taagtaagcg aagggtctta
    16201 tcaactatga tgaggctttt tgctttttga cttagtaaga tgataccttt ttaaacacca
    16261 taataagcac taattgctca atgatactag taaagtattt gtttgccatt gtcttatttt
    16321 tgactcatat ctctaaatga taaaacctag tttttaatag agctaagacc atttttggtg
    16381 tcgttgttct catttagtag tgaaaaaatg agtatttgca agggtctaac ggtcgatttg
    16441 tgttataata ttgaaaaagg agaaattatg accgttactg taaagatgct agtgcaaaaa
    16501 gttaaacttg atgtggttta tgctacagat aacttgctgt caaaagagat aacaacatca
    16561 gatatttcac gtccaggtct tgaaatgact ggttattttg attattatgc tccagaaagg
    16621 ttgcagctat ttggaatgaa agagtggtct tatcttacac agatgacttc tcacaaccgt
    16681 tattctgttt taaaagagat gttcaaaaag gacactcctg cagtggttgt ctctagaaat
    16741 ttagccattc caaaagaaat ggttcaagct gcaaaagaag aaggtatttc acttttaagt
    16801 agccgtgttt caactagccg cttagctgga gaaatgtctt attttcttga cgcttcttta
    16861 gctgaacgta ctagtgttca cggcgtttta atggatattt atggtatggg ggttcttatc
    16921 caaggggatt ctggaattgg taaaagtgag actggtttag aattagttaa gcgagggcat
    16981 cgtttggttg cagatgaccg tgtggatgtc tatgccaaag atgaagaaac cctttgggga
    17041 gagccagcag agatcttgcg ccacttgctt gaaattcgtg gggtaggtat tattgatgtg
    17101 atgtcgcttt atggagctag tgctgtgaag gactcatcac aagttcaatt ggccatttac
    17161 cttgaaaact ttgaggctgg taaagttttt gatcgtctcg gaaacggtaa tgaggagata
    17221 actttctcag gagtgagaat ccctcgtatt cgtattccgg taaaaacagg tcgaaatgtt
    17281 tcagtggtta ttgaagccgc tgcgatgaat catcgggcta aagaaatggg ctttgatgct
    17341 acaaaaactt ttgaagatcg tttaactcaa ctaatcacca aaaatgaggt gagtcaatga
    17401 tcaatcccat tgccttaaaa tgtggtccac tagccatcca ctggtatgct ctatgtatct
    17461 tgtcaggact tgttttggcg gtttacttag catcaaaaga agcacccaaa aaaggaatat
    17521 catctgatgc tattttcgat tttattctga ttgcttttcc acttgctatt gttggtgcaa
    17581 gaatttacta tgttattttt gaatggtctt attatgtcaa gcatttagat gaaatcatag
    17641 ccatttggaa tggcggtatt gctatttatg gcggtctcat tacaggagct cttgtacttt
    17701 tggcttactg ttataacaag gtgctcaatc ccattcattt tttagatatt gccgcaccaa
    17761 gtgtcatggt cgctcaagct atcggtcgct ggggaaattt tatcaaccaa gaagcctatg
    17821 gtaaagctgt gagccagtta aattacttac caagctttat tcaaaagcaa atgtttatag
    17881 agggaagtta ccgcattccg acctttctct atgaatcact ttggaatctt ttgggctttg
    17941 tcattattat gatgtggcgt cgtaagccaa aaagtctatt agatggagaa atctttgcat
    18001 tttacttaat ttggtatggt agtggaagac tagtcattga aggtatgcga acagatagtc
    18061 ttatgttttt aggtattcgc atctcccaat atgtgtctgc cttattaatt attattggct
    18121 taatctttgt tataaaaaga cgtcgtcaaa aaggaatttc ttattatcaa gaataaggat
    18181 agaaaaagga gaaacttatg gacttagttg gaatctcact gatgattatt gcactcgcat
    18241 ttgttgcttt ggtgattttc ttgattattg tattaaagaa agtctcagaa acaattgatg
    18301 aagccaaaaa aacgatttct gtattgacaa gtgatgttaa tgtgacactt catcaaacta
    18361 atgatatttt agcaaaagct aatatccttg ttgaagatgt taatggtaaa gtagcaacca
    18421 tcgatccact gtttgttgct attgctgatt tgtcagaaag tctttcagat ttaaatagtc
    18481 aagcaaggca ttttgggcaa aaagcaacta atgctacagg taatgtttca aaagctggaa
    18541 aattagcatt agttggtaaa gtagcctcaa aagtatttgg aaaaaaagga gaaaagcatg
    18601 aataaaagtt tcaaaaactt agtgattgga gctgtttcag gagtagcggc agcttacttc
    18661 ttatcaacag aaaaaggcaa ggctttgaaa aatcgtgctg aaaaagctta tcaagcctac
    18721 aaagaaagtc cagatgatta ccaccaattt gctaaagaaa aaggtagtga atacagccat
    18781 ttagcacgtg acactttcta tgatgtgaaa gataagttgg cttctggtga cttaactaaa
    18841 gaggacatgt tagacttgct caaagataaa acaacagctt tcgtgcaaaa aacaaaagaa
    18901 acccttgccg aagttgaagc gaaagaaaag caagatgatg ttatcattga tttaaatgaa
    18961 gaagacatca tcattgacta tactgaacaa gatgagcctg ttagtgatac actagataaa
    19021 cactaactaa aacgacctaa aacatagaag aagaaaagat tgaaggatct gatcactagt
    19081 cccgatggtt agttttaggc taactgaaga aggggggatt gtggcttcaa tctttttttg
    19141 tttttgacac aaaaaaaaga gtcacgtaaa acggactctg gaagttacat cagtaatgat
    19201 ttgataacct tggcgaataa ggaagtaatg cctaagctga tgatgcttgc aaataagaaa
    19261 gcaaacattg gcgctaaatt cattacgagc aggacaaatg caaataaaac ggtaataagg
    19321 ctgaaactag cgatacgagc aaagaagact aattctttta gctttgcact ttggccattg
    19381 aactcttgaa aatctcgaaa tttactttga gattcttggt aagaatcatc ctgttcaacc
    19441 gaattatgct tctttaacgg tgcaggcata gtcctctcct ttacttaaca tactaagtaa
    19501 ttctatcata aaagtctctt cttgtcatct ttttttaaaa gatttgaaaa gatttactaa
    19561 tgacaagtga cttatcatgc tataacagta aggggactag cttaacgttt gggcttttgc
    19621 aagaaatatg cttaaggtct taaaattttt ggtataataa agcttatatg gaaaaaataa
    19681 ttattacagc cacagctgaa agcattgagc aagtcaaagc tttattagct gctggtgttg
    19741 atcgtattta tgttggtgaa gccaattacg ggttacgtct tccccataat ttttcttatg
    19801 atgaattgag acaaattgcc aaactagtgc atgatgcagg caaagagttg acagtagctt
    19861 gcaatgcttt gatgcatcaa gatatgatgg atcagatcaa acccttttta gacttaatga
    19921 tagagattgc tgttgattat cttgtggttg gtgatgcagg tgtgttttat gtcaataaaa
    19981 gggatggcta taactttaaa ctgatttatg atacctctgt ttttgtgact tctagccgtc
    20041 aggtaaattt ctgggggcaa catggtgctg ttgaaagtgt tttagcaagg gaaatcccat
    20101 cagcagagtt attcacctta gctgaaaatt tggaatttcc agcagaggtg ctagtttacg
    20161 gcgcctcggt gattcatcac tcgaaacgtc ccttgctaga aaattattac cattttacaa
    20221 agattgatga tgaggttagt cgtgaacgag gacttttctt ggcagaacca ggagatgcta
    20281 gcagccatta ctccatttat gaagacaatc atggcactca tattttcatt aataacgata
    20341 tcgacatgat gtctaaattg ggtgagctgt atgcgcatgg cttaactcat tggaagctag
    20401 atggcattta ctgtccaggt gatgattttg tcgctattac taaattgttt attcaggcta
    20461 aaaccttatt agaagctggg caatttaccc aagaagaagc tgaaaagctt gatcaagcag
    20521 tgcatgccca tcatccagct ggccgtggat tagatactgg cttttatgag ttcgatccaa
    20581 aaaccgttaa ataagtaatc cttgtcttga gtgagtgggc aagacagggt tatgacacca
    20641 ttacacaggt aatctaccta tcttgaaaat agaaagaata tcacatgtca catatgaaaa
    20701 aacgtcccga ggtcttatca cctgctggaa cacttgaaaa attaaaagtt gcgattgact
    20761 atggcgcaga tgctgttttt gttggagggc aggcctatgg cctaagaagc cgcgctggta
    20821 acttctctat ggaagaattg caagaaggca ttgattatgc acatgcgcgt ggagctaagg
    20881 tctatgttgc tgctaacatg gttacccacg aagggaacga aattggtgcg ggcgagtggt
    20941 ttcgtcaact gcgtgatatg gggcttgatg cggtcattgt ttcagatcca gccttgattg
    21001 ttatttgttc aacagaagcc ccaggtttgg aaattcattt gtcaacgcaa gcttcatcta
    21061 ccaattacga gacctttgaa ttttggaaag ccatgggctt gacccgagtt gttttagctc
    21121 gcgaggttaa tatggccgag ttagcagaaa tccgcaagcg gacagatgtg gaaattgaag
    21181 cctttgtcca tggagccatg tgtatctctt attcaggccg ctgtgttttg tcaaaccaca
    21241 tgagtcaccg tgatgccaac aggggcggct gctcacagtc ttgccgctgg aagtatgatt
    21301 tgtatgacat gccatttgga ggagagcgcc gctccttaaa aggggaaatt ccagaagact
    21361 attctatgtc ctctgttgac atgtgtatga ttgaccatat tcctgacctg attgaaaatg
    21421 gggttgatag cttaaaaatt gaaggccgaa tgaaatctat ccactacgtc tcaaccgtaa
    21481 ccaactgtta caaggcggct gtagatgctt acatggaaag cccagaagct ttttatgcta
    21541 tcaaagagga attgattgac gagttgtgga aggttgccca gcgcgagttg gctacaggtt
    21601 tttactatgg tatcccaact gaaaatgaac aattatttgg tgctcgccgc aaaattccac
    21661 aatataaatt tgtcggagaa gtagttgcct ttgactcagc tagcatgaca gcgagcattc
    21721 gtcagcgtaa tgtcatcatg gaaggcgatc ggattgaatg ttatggacca ggtttccgtc
    21781 attttgaaac ggttgttaag gacttacatg atgcggatgg ccaaaagatt gaccgtgccc
    21841 caaatccaat ggaactctta accatctctt taccgagaga agttaagcca ggggatatga
    21901 ttagggcttg caaggaaggt ctggttaacc tctatcaaaa agatggcacc agtaaaactg
    21961 ttagaacata gtaacaagaa atactagagg ccctcttttt ccaaatggta tacgaccata
    22021 gttgggaaaa gagagcctgt tttttttgaa aattggatat cacaatagct tattttctca
    22081 aaacttgata gaataatagg agaatgagtc ataaaaaaag tgaaaaaaag atgatttttt
    22141 ccactttaat ttcgaatagt atagatgagg aggaaaacta atggcagaat ttacattcaa
    22201 cattgaggaa catttactca ccttatcaga aaatgataaa ggttggacga aagaattgaa
    22261 ccgcgtcagc tttaatggcg cagaagcgaa atgggatatc cgcacgtgga gtccagacca
    22321 tacgaaaatg gggaaaggca ttactcttac taatgaagaa tttaaaacca tcttagacgc
    22381 ttttcgtaag taatgttacc ttaatcgaaa cataatccct cgttcgcccc tgtcctttta
    22441 acctggtgat gacatcgcta ggttaaaagg acaggggcga atagaaggat tatttttttg
    22501 aattgaggcg atcagcaagg ccgacaagta ccaaaattaa gcctagccca agaaaaatcc
    22561 atttggcagc taaaaggcca taaagcaaga agatagcagc actaatgtag gagatatatt
    22621 ctttggtcat cttgttaagt cactttctat aagctactgt taataaacca gtcttcatgg
    22681 taatgaagac tggttagaga taataaaacg ttatgttata ttgccactta tcggttttaa
    22741 gatatgaata caaatcttaa aaaagttaag gtttcatcgt tgggaataaa agcacatctc
    22801 tgattgttgt tgtgtttgtt aataacatgc aaagacgatc aatcccgatt ccgagtccac
    22861 cggttggcgg cataccatat tcaagagctt caacgaagtc gtagtcaatg ccagttgctt
    22921 cgtcatcacc aagttcttta gcttgtgctt gtgcttcaaa acgagataat tggtcaatgg
    22981 gatcattcaa ctctgtgaaa gcattggcgt attctttggt catgatgaaa agttcgaagc
    23041 ggtcggtgaa gcgggtatct tctggattct tcttagccaa aggcgatact tcaacaggat
    23101 gaccaaacac aaaggttggt tggaccaagg tttcttcaac aaattcctcg aagaaagcgt
    23161 tgatgatatg tccgacactt atgaagtgtt tttcgagtgg gacctgtttt tctttggcaa
    23221 gtgcaatagc ttcttcgaca gtcatttcag gccagaaatc agcacctgtc acttccttga
    23281 tagcatctac catgtgaaca cgtttgaaag gttcattgat acggatttca gttccttgat
    23341 aatcaatagg gccatcacct ctaacagctt tagcagcatg ttggataatg ccttctgtca
    23401 ggttcatgat atcaagatag tctgcatagg cttggtaaac ctcaatagaa gtgaactcag
    23461 gattatgagt agcatccatt ccctcgttac ggaagatacg accaatttca tagacacgtt
    23521 ccataccacc aacaatcaaa cgtttcaaat gaagttctgt tgcgatacga agcaccatat
    23581 caatgttttg agcattatgg tgagtaacga aaggacgagc agcagcacca ccagcctcgt
    23641 tatgaagcac aggcgtttct acttctagga aatcaagacc gtctaaataa cgacggattt
    23701 ctgaaatcat tttggaacgg gtcacgaagc ggtcaaagct ttcacgattt gaaattaaat
    23761 caaggtgacg cttacggtaa atggtttcaa tatcagttaa tccgtggaat ttttcaggaa
    23821 gaggacgaag tgatttagaa aggtgagtca acttggttgc cttgattgac aactcgccca
    23881 tgtctgtacg catgacttcg ccttcaacgc cgataaagtc gcctaaatcg gcttttttga
    23941 agatttcata gttgtcttcg ccaacagagt ccttgcgaac ataaagttgg atttggcctt
    24001 cacggtcttg aagatgagca aaaccaacct tacctttgcc acgttttgtc atcaagcggc
    24061 cagcaacaat agctgtttcg tttaactcat gtaattcttc ttttgtttta tcagcatact
    24121 tttcttttaa ttcagcagaa ttggctgtgc ggtcaaagcg tttaccgaaa ggatcaattc
    24181 cttgttcagc cagcgccgtc attttttcac gacggacaat ctgttggtca tttaattctt
    24241 cgatgtgttg attagacata ttttcctcca atacgatttc ctttccattg tatcataaaa
    24301 ggggctagaa tacacctata tttcgttgga aaatgcgact gcagcggggc atttttttga
    24361 aaatgaaatt gaaaagccta atggaaaata gtataatgat tgggatatta aactagaaaa
    24421 gaaaagagac tcatgattac tgctattgtt tttgatgtgg atgacacaat ttacgaccag
    24481 caagcgcctt atcgaatcgc catggaaaag tgcttcccag attttgatat gtcagtaatg
    24541 aatcaagctt atattcgctt tcgtcactat tcagatgttg gattcccaag agtaatggca
    24601 ggggagtgga ccacagaata tttccgattc tggcgttgca aggaaacact gcttgagttt
    24661 ggctatcgag aaatcgacga agctgcggga gtacattttc aagaagtcta tgagcacgaa
    24721 cttgagaaca ttaccatgtt agatgagatg cgcatgaccc ttgacttttt aaaatcaaag
    24781 aatgttccta tggggattat taccaatggg ccaacagaac atcagctgaa aaaagttcgt
    24841 aaattagggc tttatgatta tattgatcct aagcgtgtca ttgtgagcca agcaacaggc
    24901 tttcaaaaac cagaaaaaga aatttttaac ctggcagcag aacaatttga catgaaccca
    24961 caaaccacac tatatgttgg ggactcttat gacaatgata tcatgggtgc ctttaatggt
    25021 ggttggcatt ccatgtggtt taatcataga ggtcgtcagc taaaaccagg cactaagcct
    25081 gtttatgatg tggctattga taactttgaa cagctctttg gtgccgttaa agtactcttt
    25141 gatttacctg ataataaatt tatttttgat gtcaatgaca agaaaaatcc aattttacag
    25201 atgggaatca ataatggctt gatgatggca gcagagcgtt tacttgaaag caacatgagc
    25261 attgacaagg tggttatctt gcttcggtta accaagcaac aagaaaaagt tttgcgctta
    25321 aaatatgcca gatagatgaa accataatag cccactagat aataataaaa aaagctagca
    25381 aagtgagtgt cttgtcagta agagatcaat gtgttagctt tttttattat tttctagtgg
    25441 ttttacacct ctagaaaaga tttatcattc caaattaaac agtcataagt taaataatct
    25501 ttagtttcaa gaatagtaag actggcatta tctaagccac ctttagcgag taaaagagca
    25561 ggttcaaaac ctaataatga gcgaatagtt gctgttaagt tagcgccgtg tcctacaata
    25621 agaacgtttt gataatgttt atctttaaac gattggataa gatggcagac acgttgagtc
    25681 gtttggtaaa ttgattcagc ctcgaactga tctggtttga actgggctag attctctcga
    25741 aaagccagca tttgttgggg atatatagct gccattgttg ctattttagc cccttccaat
    25801 ttacctaatc tccactcccg aagctggtcg gtgtggtaaa gttttggctg ttggtcaaaa
    25861 gcatctaaga taatagctgc tgttgccata gctctttgaa ggtcgctagt ataaacggca
    25921 tcaaaagcca ccttagctaa ctctttgcca agtaagtgaa tttcgtcttt tgcctcttca
    25981 agtaatggcg aatcgccccc agcgccttga aagcgacctt ctaaattcca aagggttttc
    26041 ccatgtctta caaaatataa tttcatttaa gcctcctttt agagataact gatgcgagcg
    26101 ctaaaaataa aaaagtaacc agaaaaagtt taggcatcac caagcaaaaa taatacctat
    26161 agtgaaaaga taaagtaaaa aagcgtagta taagtgtata atagctaggt tctgattaaa
    26221 gtgtaaagcc catattagat ctaagacaaa tcgacctgaa tttgtcgtga tatcaagtct
    26281 ctacaaaaga aaaagattaa caggatcaat gttaaagcag ttgagatcaa aataatacta
    26341 aacaaagact agcttaatca aggcgaaaaa cttaaaaaag aaaccagata aagttggcag
    26401 tagtgttcat tttctcttct ttaaatcagc aaagcttgcg ccaacgaaat cagctagagc
    26461 ctggctagaa atctttatag aacgcccaac ttcaccagct gaaacgatta tttgaccttt
    26521 ttccagtgca gtttggtcaa taaaaatagg atatgaatgt ttttgacgaa tcccaacagg
    26581 attattggca ccgtgaatat agcctgttgt cttttgcaag tctttttgag gaaccatgga
    26641 cacttttttg ttacctgata cttttgccaa ttgtttttct gataagtgtt ctgttaatgg
    26701 aataatgcca attagaggac ctgtttgatc accagtcaga gcaagtgtct tgtaaatatc
    26761 tgatggttga agatcatctg gaaagtcgcc ttctaaagca ttaagcttga gtccttgatg
    26821 agcaatatta gccttatcga ggatttgttc tactaaggtt tttttgagtt ttgttttttt
    26881 agccatatca agtccttacc tttatctaaa cataaaaaaa tggtataaca acattattat
    26941 accatttttt taatgtaaga ttcaaatgac taaaaattag tctttgggat caaataattg
    27001 aggatgaatt ggtaaagcaa tcattaacgc taaacatgtt attaaaaaag ttaggacacc
    27061 agctgtacca ttaacgctaa aagaatacca gacagcggac atgcctttag gggcgtaact
    27121 gccccagaaa atgattcctg caaggaagtg ccacaagtaa cgtactgtaa cggctagtaa
    27181 actagccatt attgcaagaa aaacggcaaa aaaggtttgt tgtcttctta aagttttaat
    27241 caaactatta gagaaactac cggctaatcc catagaggta aaggctaaga tatattcaat
    27301 aaagacttgg gacatgctga gatagtaaac ttttccaagt acaaagtgaa gtagccccca
    27361 aatgagaccc gccaacatgc cgtactttaa cccacggcgc aaagagaaaa taaccagtgc
    27421 aatagcacca taagaaggac taaaccagcc agcaaaatct ggaataaatg aaagggtcat
    27481 cgccaatgca gcaaaaatag cagcttcgat aaggtatttg acattggtgt ttggtgacat
    27541 aaaaaactcc ttttgtgcac aaaaagagta tcgctttcca atcattgatt attggtcaca
    27601 atccctacgc ttgtactaac aagatcaggt cctcaggatt tcgcaattgc gatctcagcc
    27661 aaagcactcc tttgtgaaat attatagtgc tttcattata tgatgagata atctccttgt
    27721 caaggataag gggttttaaa ttattgacct agagtttttc ctggtaagat gtaaactata
    27781 aaaaaagatt agccatgatg ctaacctctt aattgttgga gttgccaaat aacttctcaa
    27841 acgttttttt agtgtctttt gttacggcaa tttgatttaa atctaaagca ttgttaaaac
    27901 cactgagata accttgtgag gtgtattggt gtaaatcgta atctaaggtt gtattaggag
    27961 cagcctcata atagccagaa tcactaccat aagtcggaat ccatacagaa tcgaaacctt
    28021 ttgttgaaat atcttgttct gccataaaat aagttccaat atagagacca acattttcag
    28081 caccaagttt tttaagctct tctcggaagg ctgttacgcc tttattcata tctttcatag
    28141 tggcttcttc gacatcaatc cagtagtaag ttggattata gggagcagcg tttttgtaga
    28201 aagctcgggc ctcttctttc atctctttag tactacgacc aagtgcgtaa ctgtaaacag
    28261 ctacaggaac atttcgtttt tgaaattctt tgatatgcgt tttaaaagat ttgtcaattc
    28321 cagttgtaaa agcagcgttg ttatgagctg taatttgcga tcctccatag acacgtacaa
    28381 ttgcgccaga gatgtgacgt gacaatgtgt cataatcaat ttcttcaggg agttgccagc
    28441 cggaaacatc aacaatagga tttaaaataa agtcttcggt ttcagaagtg ctagtttttg
    28501 ctttaccagg attactggtt gcaataggaa tatgactctt agcgtcttca acttcttttt
    28561 gtttcgcatg attagcttgt ctttttccga taatcaatac cattgccagt aaaataaaga
    28621 agactagcac aacaataggt tttatttttc ttctcattaa ctgttattgt accctaatta
    28681 ctaaaaaaaa tcaaaatatc ctaactgttt tcttatattg tcttgcattt taaggtattc
    28741 tctttgagaa gttacaaatg agatcctctc taactatgtc aagtttatgt cactatctct
    28801 tatagttggt agctatattc tttacaatat tagtttagtc tttgactata tcatgacagt
    28861 cagcaagtac tgttttgtta tttaattctc atgttattat catttgataa ataagtgagc
    28921 tccaaactgg taaacgctct gtaaatctgt cataatagag aaaaaaacga ggaagaagtt
    28981 tatgtcagct aagcttatga gtcgcattgc tatcatgtca gccctatgtg ttgtgttgag
    29041 aatggttttt agcagcctgc ctaacgtgca gcctgtgacg gcatttttac tcagttatct
    29101 tctttacttt gggttagccg aggctgtatt agttatgatg ttgtgcttgt ttttatcagc
    29161 ctttttgctg ggatttggcc cttgggtctt ttggcaagtt acttgttttg tgcttgttct
    29221 tttattatgg cgttttgtct tgtacccttt gtctcagcaa ttccccaaat atcagcttgg
    29281 ctgtcaggct ttcttggtcg ccttatgtgg cctcctttat ggggtgttga tagatacttg
    29341 ttttgcgtat ttgtatagta tgccttggtg gagctatgtt ctagctggga tgccttttaa
    29401 tatagcgcat gctttatcaa ctctcgtctt ttttccagtt gtgatgatgt tatttaggag
    29461 gttaatcggt gaacaaaaga tttaaaacag gatttctagc gcttgttgct atgctacttg
    29521 ttgcttgctc gcaaggaaca aaacaaatac agacgactcc aagcgttcca aaagcagacc
    29581 atcacgttcg cttagttgtc aaagaagata ccaatactgt tgacgaaaaa gtttcttttg
    29641 gaaaaggaga tacggtgctt gaggttctca aagataatta tgaggttaaa gaaaaagatg
    29701 gttttatcac agcaattgat ggtatcgagc aagacacgaa agctaacaaa tactggcttt
    29761 ttaaggtgaa tggaaagatg gcagataagg gtgccgatca aattaccgtt aaagatggtg
    29821 atagcattga attttatcaa gaagttttta attagtaact ataatataaa atagacttgg
    29881 cacgccaagt ctattttata ttaaccaaga agtgctttaa ggtcttcttc aattagttta
    29941 ggatctgtct ttgaggaata gcgtttaatg acttgaccat tttggtcaat gagaaattta
    30001 gtgaaattcc attcgatgcg tttcccaagg ggaccacttt tttcttcttt taaccaggtg
    30061 aacaaaggat cagcgtcttt accattcact ttgatttttg caaagcgagg gaaagtagtg
    30121 tgataggtca gactgcaaaa gtgattaatc tcctcagcat ctcctggagc ttgatttaaa
    30181 aattggttgc aaggaaaatc taagacctca aatcccttgt catggtatgt gtcatatagt
    30241 gcttgcaagg cctggtattg tggggttagc ccacatttgg tagctgtatt cacgaccaaa
    30301 accacttttt ctttgtagtc aactagtgag atgtcactgc cgtcctgagc cttaaccgta
    30361 aaatcataga gattaggcat gtgacatatc ctcggtgtaa ctgataattt ggtcaacggt
    30421 atcactcaag aattgaatgg tatctcgaag aggcttttca gtggcaatgt ctgccccaat
    30481 gagcattgca gtatcaagag gcgtacggct gccacctgat tttaggaagt caagccactc
    30541 cttggcacca tttggattat gtttaaggtt gaggtaacca gctgttgaaa taacaagccc
    30601 agcagaatag gtataactat ataagcccat gtagtaatgt gcttggcgca tccaggtaag
    30661 agctgcgtca tcgtcaatgt caacggcatc tccccagaag tctgttaaga cctctttcat
    30721 catcgcattt aattggtcag ctccaaaggt accgccttct tcaataaggg tgtaaacctt
    30781 acgttggaaa gccgcttcca ataggtgagt gatgaagtta tgaaagtaag tatctgttaa
    30841 acggtgagca agggcaaaac gtttttgacg agggtcatca aactgatgtt ccaagtaatc
    30901 actaagcatc aattcattaa aggtcgatgg cgcttcgacg taataagttg acatatgggt
    30961 gttgaagtaa ctttggtgat tatctgaaaa aatgaattgg ccagagtgac cgatttcatg
    31021 aataagggta taaacatcag acattcttcc agtccaactc attaagacat acggatgaac
    31081 cttgtaggga tcagcggcat aaccaccaga atccttattg gcgttagcag caaagtcaac
    31141 ccagcgttct gtctgataac gttcgatttc tttcgtgtat tcttgcccta atggggctag
    31201 agatttcatc acgaggtcat aggcaccatc aatgctgacc tctggattga gatcattgtc
    31261 aatatctagc ttccagtcag caaaagtcat tttctcaaga ccattgactt gggcgacatg
    31321 ttttaagaat ttctgagcaa ccggtccaaa ttcagtcatg atgaggtcaa tttggcggtc
    31381 gaacaagcta cgatccactt cctgttcagc taggaggtaa tcaaagacag aagcgtagcc
    31441 tttcatatcc gctaacaatt tttcagattt aaccttggct aagtaagccg ctgcagctgt
    31501 attttggtgt ttacggagac cttttgaaaa agagcggaag gctttttcac gaatctcagc
    31561 attttcgtga ttttgataga aattttcgta agaaacaaag ctatttttat aggttttacc
    31621 atccacctca aaatcatcca tgtcaaagtc accagcccgc attttggtgt aaatatcata
    31681 gggcgcattg ataacctcgc gtaagttagc caaagctttt tccacatcag gacttaagag
    31741 gtgttctttt tgaatttttg ccatgcgaat agctgcgctg aaataagggt tcttttctaa
    31801 tgtatctaac acgtcaaggt cggcattggc taaggcggtg tcaaagaagc taagggcaac
    31861 gctagcttta gtcatgaaat catcgccagc ctgagcaatt tgagcaaaac tttcatctga
    31921 aaagtcagtg gtttgaggca taaaggcata agtgccaata tgactcattt gaatataaat
    31981 atgctcaatt tctattaagg cctgagtgaa atcgtccacc gacgttaagc ggccttcata
    32041 attgcgctta aacaggtcaa tatcttgtaa ggctttttca atagcgagta aaaaatcttg
    32101 gcggtctttg tagagcgctg ttagatccca aagttcattt tcagggaatt ctgaacgttt
    32161 tttcaattcc atagttgtct ccttaacaat atactcaaga ctagtataac agaattttag
    32221 tggaatatgg agactaaacc tatccaaaca ttctttaaaa taaagcgctt acttttgtta
    32281 aaaaacaaac gttatgaaca tgatcacttt tatttttggt aaaaagtggt atgatagaag
    32341 aaactagcaa agaaggagat ggtcatttgc cacttaaaaa gttagagagt agtaacaatc
    32401 aagatatcat tgctgaagaa gttgctcttt tgaaagaaat gttggaaaat atcacacgac
    32461 ggatgattgg agatgatgcg tttacagtta tcgagtctat tatggtgtta tctgaaaaac
    32521 aagattacat agaattagaa aaagttgtcg ccaatatttc aaatcaagaa atggaagtga
    32581 tttccaggta tttttctatt ttacccttgc taatcaatat ttcagaagat gtcgatttag
    32641 cctatgaaat caattatcaa aataatacgg atactgatta tttaggaaaa ttagccctaa
    32701 ccatcaagga tcttgctgga aaagataatg gtaaagacat tttggagcag gttaatgtgg
    32761 ttcctgtttt aacagcacat ccgacgcaag tacaacgtaa aacgattctg gaattgacaa
    32821 ctcacattca taaacttctg cgcaaatacc gtgatgctaa ggctggtgtg attaatcttg
    32881 agaaatggcg tcaggagcta tatcgttata ttgaaatgat catgcagaca gatattattc
    32941 gcgagaaaaa gcttcaggtg aaaaacgaga taaaaaatgt catgcagtat tacgatggtt
    33001 ctctcattca agcagtgacc aagttgacaa cagagtacaa aaacttagcc caaaaacacg
    33061 gtctagagtt agacaatccc aaacccatta ccatggggat gtggattggt ggggaccgtg
    33121 atgggaaccc ctttgtcaca gctgaaacct tgtgcttgtc agctacggtt caaagtgagg
    33181 ttatcctcaa ttactacatt gacgaattag cagcccttta ccgaacattt tcactgtcgt
    33241 caaccttggt acaacccaac tcggaagtgg aacgtttagc cagtttgtct caggaccaat
    33301 cgatttaccg tggaaatgaa ccttatcgca gagcttttca ttatattcaa tcgcgtctta
    33361 aacaaacaca aattcaacta actaatcagc cagcagctcg tatgagtagt agtgtgggac
    33421 taaacacatc tgcttggtcc tcaccagcta gtttagaaaa tcccatctta gcctatgact
    33481 ctcctgttga ttttaaagct gatttaaagg ctattgagca gtcgctactt gataatggca
    33541 actccgcttt gattgagggg gatttgcgag aagtcatgca agctgttgat atttttggct
    33601 tcttcttagc aagcattgac atgaggcaag actccagtgt ccaagaagct tgtgtggcag
    33661 agttattaaa aggagccaat attgttgacg attatagctc tctttcagaa actgaaaaat
    33721 gcgatgttct cttacaacaa ttaatggagg agccaaggac tttatcctca gcggcagttg
    33781 ctaaatcaga cctattggaa aaagaactgg ctatctatac tacggcacga gaattgaaag
    33841 ataagcttgg agaagaggtt attaaacaac atattatttc acatacagaa agtgtctctg
    33901 atatgtttga gttggccatc atgcttaaag aagtgggatt ggttgaccag cagcgggctc
    33961 gtgtgcaaat tgttcccctc tttgaaacca ttgaggattt agataatgcc cgtgacatca
    34021 tggcagccta tttaagccat gacattgtca aatcttggat tgcaacgaat cgtaattacc
    34081 aagaaatcat gttaggttat tctgacagta ataaagatgg tggctacttg gcatcgggtt
    34141 ggactcttta taaagctcag aatgaattaa cggctattgg tgaggaacat ggagtgaaga
    34201 tcaccttctt ccatggtcgt ggaggaacag ttggtcgagg aggtggccct tcttatgatg
    34261 ccattacttc acaacctttt ggttccatca aagatcggat tcgtctgaca gagcaagggg
    34321 aaattattga aaacaaatac ggcaataaag atgtggctta ttaccattta gaaatgttga
    34381 tttcagcttc tatcaatcgt atggtgactc aaatgataac agatcctaat gagattgata
    34441 gttttcgaga aatcatggat agcattgttg ctgatagcaa tatcatttat cgaaaattgg
    34501 tttttgacaa tccccatttc tatgattatt tctttgaggc aagtccgatt aaggaagttt
    34561 ccagtctcaa cattgggtca agaccagcgg cccgtaaaac gattacggaa attacaggct
    34621 tgcgtgccat tccttgggtc ttttcatggt cacaaaatcg catcatgttt ccaggttggt
    34681 atggggtagg ttcagccttt aaacgttata ttgaccgagc acaaggtaac cttgaacgcc
    34741 tccaacatat gtatcagacg tggccttttt tccattcctt gttatcaaat gttgatatgg
    34801 tattatctaa atcaaacatg aatattgcct ttcagtatgc acaactagct gaaaggcagg
    34861 atgttcgaga tgttttttat gagattttgg atgagtggca attgacaaaa aatgttattc
    34921 ttgctatcca agaccatgat gctctattgg aggataatcc ttcccttaag catagcttga
    34981 aatcacgctt gccgtatttt aatgtgttga actatattca aattgaattg attaaacgtt
    35041 ggcgtaataa tcaacttgac gaaaatgatg aaaaattgat ccatacaact atcaatggca
    35101 tagcgactgg tttacgtaat tcaggctaat gctcttgagt attaattggt atttatagaa
    35161 gttttcaagt gactaatcag aattttaaag gttagccctt ggagcttctt tttttgagga
    35221 ttcttgactt tttcttttgt ttgatataga aagatgttat aatgctaaat gattatctca
    35281 agaagtagag ggaaaactat gaagattgat aaaaggcacc tcttaaatta ttctatatta
    35341 ttgccttatt taattttatc ggtgataggc ttaataatgg tttactcaac cacaagtgtc
    35401 agcttgattc aagcacatgc taatccattt aaatcggtga ttaaccaggg agttttttgg
    35461 ataataagtc tagtggctat tacatttatc tataaattaa aattaaattt tttaacgaat
    35521 acaagggtat taactgtggt tatgttagga gaggcctttc ttttaatcat tgcccgcttc
    35581 tttacaactg ctatcaaagg agcgcatggt tggattgtga tcggaccagt cagctttcag
    35641 cctgctgagt atttaaagat cattatggta tggtatttgg cattgacctt tgctaagatc
    35701 caaaaaaaca ttagccttta tgattatcaa gcactaactc gtcgaaaatg gtggccaaca
    35761 caatggaacg atttacggga ctggcgtgtt tattctttgt tgatggtact tttggttgct
    35821 gctcagcctg acttgggaaa tgcttccatt attgtattga cagccattat tatgttttct
    35881 atcagtggca ttggttaccg atggttttcg gctatcctag tcatgattac cggtctatcc
    35941 acggtctttc ttgggactat tgccgttatt ggggtagaaa gagttgctaa gattcctgtt
    36001 tttggctatg tcgctaaacg ttttagtgcc ttttttaatc cttttcatga cttgaccgat
    36061 tcaggtcacc aattagccaa ttcttactat gctatgagta atggtgggtg gtttggccaa
    36121 gggttaggaa attccattga aaagcgtggc tatttgcccg aagcacagac agactttgtc
    36181 ttttcagttg tcattgaaga gttaggtcta ataggagcag ggtttatttt ggcacttgtt
    36241 ttcttcttaa ttttacgtat tatgaatgtt ggtattaaag caaaaaatcc ttttaatgcc
    36301 atgatggctt taggagtagg cggtatgatg ctcatgcaag tctttgttaa tattggtggt
    36361 atctcaggct taattccatc tactggtgtt accttccctt ttttgtctca aggtggaaat
    36421 agcttacttg tcttatctgt tgcagtgggt tttgtactaa atattgatgc tagcgaaaag
    36481 cgagatgata tatttaaaga agctgaatta tcttatcgaa aggacactcg aaaagaaaat
    36541 agtaaagttg taaatatcaa gcaatttcaa taatattcta aaatctcctt taaggagatt
    36601 ttagaatata gacaatccca gtttgatgct caaaaaactt gaactgctct gctgatttct
    36661 tatttttgcg tgtgacatga gcccaaacag ctgctttttg ctgtggcaaa aataaagcgt
    36721 ggaattccaa aggaagtcgc tgctataagc accacctaag gagagtatca aaaaagactt
    36781 tttcatctat ttaaaaaata aagaaatggc aaaaaacata aaatacttgc attttcattg
    36841 taatttgcta caatagtaag gtaaagttag actgtatggc ctaccgtcta tctataaaat
    36901 atattttatt ggaggctttt cctaaaatgg caaaagaaaa atacgatcgt agtaaacccc
    36961 acgttaacat tggtacaatc ggacacgttg accatggtaa aactacttta acagctgcaa
    37021 tcacaactgt attggcacgt cgcttgcctt catcagttaa ccaaccaaaa gattacgctt
    37081 ctatcgatgc tgctccagaa gaacgcgaac gcggaatcac tatcaacact gcacacgttg
    37141 agtacgaaac tgcaactcgt cactatgcgc acatcgacgc tccaggacac gcggactacg
    37201 ttaaaaacat gatcactggt gccgctcaaa tggacggagc tatccttgta gttgcttcaa
    37261 ctgatggacc aatgccacaa actcgtgagc acatccttct ttcacgtcag gttggtgtta
    37321 aacaccttat cgtgttcatg aacaaagttg accttgttga tgacgaagag ttgcttgaat
    37381 tagttgagat ggaaattcgt gaccttcttt cagaatacga tttcccaggt gatgaccttc
    37441 cagttatcca aggttcagct cttaaagctc ttgaaggcga cactaaattt gaagacatca
    37501 tcatggaatt gatggatact gttgattcat acattccaga accagaacgc gacactgaca
    37561 aaccattgct tcttccagtc gaagacgtat tctcaattac aggtcgtggt acagttgctt
    37621 caggacgtat cgaccgtggt actgttcgtg tcaacgacga aatcgaaatc gttggtatca
    37681 aagaagaaac taaaaaagct gttgttactg gtgttgaaat gttccgtaaa caacttgacg
    37741 aaggtcttgc aggagacaac gtaggtatcc ttcttcgtgg tgttcaacgt gacgaaatcg
    37801 aacgtggtca agttattgct aaaccaagtt caatcaaccc acacactaaa ttcaaaggtg
    37861 aagtatatat cctttctaaa gacgaaggtg gacgtcacac tccattcttc aacaactacc
    37921 gtccacaatt ctacttccgt acaactgacg taacaggttc aatcgaactt ccagcaggta
    37981 cagaaatggt tatgcctggt gataacgtga caatcaacgt tgagttgatc cacccaatcg
    38041 ccgtagaaca aggtactact ttctcaatcc gtgaaggtgg acgtactgtt ggttcaggta
    38101 tcgtttcaga aatcgaagct taattttaat taagttccca gaatagcaat ttaagtcaga
    38161 caacttaagt ttgaagaagc ccccaattcg ggggcttttt gctatcttaa actccataaa
    38221 atgctgataa ataagaatga aaagctttca gaaaaagggt ttttatttgt gaaaatattc
    38281 ctaaaatata agcaattcct tttaatcgtc ggtcatttgt gctaaaatag aagatataaa
    38341 taaaaaaaga agaggtatgt gatatgtcac gtaaaccaat tattgctggt aactggaaaa
    38401 tgaacaaaaa ccctcaagaa gcaaaagcat tcgttgaggc tgtagcaagc aaattacctt
    38461 caactgacct tgttgatgtt gccgtagcag ccccagctgt tgatttggta accactattg
    38521 aagctgctaa agattcagtt cttaaagttg ctgcacaaaa ctgctacttt gaaaacacag
    38581 gggcattcac tggtgaaaca tcaccaaaag tgcttgctga aatgggagct gactatgttg
    38641 tgattggtca ctcagaacgc cgtgattact tccatgaaac agatgaagac attaataaaa
    38701 aagccaaagc aatctttgct aacggtttaa ctccaattgt ttgttgtggt gagtctcttg
    38761 aaacttatga agctggtaaa gccgttgagt ttgtaggtgc gcaagtttca gcagcacttg
    38821 caggtctttc agcagagcaa gtagcttcac ttgttttagc ttatgagcca atctgggcta
    38881 tcggtactgg taaatcagct actcaagatg atgctcaaaa catgtgtaaa gctgttcgtg
    38941 atgtggtagc agcagacttt gggcaagaag ttgctgataa agttcgcgtt caatacggtg
    39001 gttctgtaaa acctgaaaac gttaaagatt acatggcttg tccagatgtt gacggtgccc
    39061 ttgtaggtgg tgcatcactt gaagctgata gcttccttgc tttgcttgat ttccttaact
    39121 aagtcatcta aaaaagaaaa ggttaaatcc ttttcttttt tagatgactt aactcttact
    39181 ataagagaat aaaggtgatt ctacaggcaa atgcattagc ctaatagcgg tttaatagct
    39241 tttttgccaa tctaatgaaa tgatatttga ttggaaatgg ataacatcta aatgtccctg
    39301 gtttttgcaa aataaagcca ttgaaattct gtttaaagcg caagacaccg tctgaaccat
    39361 caaactttcc agtaatacca agaaaattat attgtttgat gcccttgtga attgccttga
    39421 gcatagcatg ctcttgtaat agagctgggc tataaaattt attaaatttg gggtaagatc
    39481 ctgaaaagag gtagacggcc tcttgttcgg tatagataaa aagacttccc gcaaggaaca
    39541 catctttagt tccatactct tcaagaaaat ggagagcttc agaaattctt acctgaaagg
    39601 tttcgaactg gctggatagt tcttttaatc tattttgctt tttttcagaa tgaggatttt
    39661 tgccaaggtc tcctttaact ttgttgatgc tggttgctag ttgtagttgt ctttgtttaa
    39721 ggttattaag gtaatcttca aaattaagag tcgcaaccat aaattcacaa gagtctccaa
    39781 aactatcata aaagtcctga tagtaagata atgatttgtc aaggtaatct ctacgatcag
    39841 aggttgcttc agtaatttct ttgaaatggt gtaactcatc tcgtttcagt tgacgtaatt
    39901 taataccaaa agtattagct ttttttatta aagcttttcc ttttttgctg aaggaacggg
    39961 ttaaacgtga ggaatcaatt ccttctaact ttttaacgta atgccaaaca ggttcaccct
    40021 caggatagcc tgtttttaaa ccgtcatgtt tatatcctaa cgccgttaaa aggctaataa
    40081 ggtcagtgtt tggacgagaa atagggatgc catcagtatc aaatgactga taattgtcgt
    40141 aaggttttaa aatgagttcg ataacgtctt tttgtttggc atagtcttta agttgagtgt
    40201 aaaaatgttc taattcttcg ggatgattgg tattagggcc tgcattgagt tccatacgcc
    40261 aacctccagc cactttttgg ctaaagacca tagcagcaac ctttagttca ccatcttttt
    40321 caagtccaag aaattgtggt tttgcccctc ttttagccat caagctggcc atttctgagg
    40381 tttggataaa ggaatgatgg acgagactgt ggcagtaatg gtcaaattgt tcttgtgaaa
    40441 tttcaattag tgccattagt tgtgctcctt aatttttttc ttaagttata ggttaagatg
    40501 gctaagcttg aaacaaggcc gacaggaatg ttgaattcac ctgcaaattc ttcgatagtg
    40561 gggttgagtc tagctttgaa atgatagagt ccaccatctt gttgattttc cacacctcct
    40621 aaattatgcc agcggcagcc tcttttaaaa gcttctttag ccgtttcata ccaggttaaa
    40681 agaggagctt gataattgcg ataatcatcg tccattcccg cataaagatt ttcagaagtc
    40741 tcgccataaa tcaaggttag ggtggcggct aatgggatgc gggtttggcc tgtagcgagc
    40801 tgctcgctta aaatggttaa atctttttgt agccgtgcaa tggttttttg attttctgct
    40861 actttgctag gtttactctt atctgttaat cgtgcttgtt ctgctaaggc cttgtccaac
    40921 tgttggatca agagtttttt ttgttcaggt aagtctaaac tagccatagt aatgtaggac
    40981 tgaccagcat aaatacctag taatttttga taataggatt tgcctcgaag gataatgcct
    41041 tttcgattct cggttttttt catcaaggct gaaaagtcgt ctagcaattc actgccacca
    41101 atcgtgacat taacaccttt attggtagcg gtacgaatgg attgcttggc ttttttgggc
    41161 aggctgtcaa agtcaaaatc cttggcgtag atgttggctt gtattcttgg ttgaatagtg
    41221 tcttcgagtt cttttgttct gccagaccat tcgacaccga gtttttttag aaaagcaata
    41281 atagagagtg tcacatcatt ttctttgctc tcttttcctt ctaaagtttg tttgatgact
    41341 aaacttggat caattttgat aaaaagcgct cgtttgcttt ttccgaaagt tttgagcgtt
    41401 ttaatgacga aatcaaggag ttcaaaattg gcgtagtcca tgattggccc acgtgggata
    41461 taaatcatag tgaaaccaag aggaagtttt ctgattaaac aagcagcagc agcaacttgt
    41521 accccatttt cataaaagct gatgcgttcg tgtttccagt tatctttgac ttttccccac
    41581 tttgaacttt gaagtaagcc agcttgtggc tgtgctaaga caaactgatc atgttcttca
    41641 ggagatattc cgattttata tgtatacatt agtttaatac ccacttgcga atagcatgtg
    41701 ccacaccact gtcattgttg gatttggtga tgtatttggc tatttttttc aattcaggaa
    41761 ccccattttc catgacaaca gggttggcaa cgacttctaa catagcacga tcattttcag
    41821 catccccgat ggccatggtt tgtgacatat ctagcccgag ttttttagct aagtgtttga
    41881 tggcattacc cttgctgacg gtttttggca tgaactctaa ataaaaaggg gttgacttga
    41941 cgatggtgta cttatcaaag aaatgttgag gaatttgctt gatggccgcg tccaaaaggt
    42001 caggttcatc aatcatcatc attttgatga tttctttatt ggtcatttct tcgggagtgc
    42061 gatagaaaat aggcatgttt accaaagtcg attcatgaac tgtgtatttt ccaatattcc
    42121 gattggcagt gtaaatacct tctttggtaa tggcatgcat gtgaactcct aattttcggc
    42181 tcaaaaattc cgtttccaga taatcgtcgt aagtcatcaa ttctttaaca atttcttcgc
    42241 cggtctcggc atcttgcacc aagccaccat taaaagtgat aacgtggttt cctttgtggt
    42301 tgagttctaa ttgttcgagt aatgaaatca ctccggcaat aggtctgcca gtagcaatca
    42361 ccacatgaac cccttgggct ttagcctctt ggacagcttg aaaaacatca tctgtaattc
    42421 gacggtcatc agtgagtaat gtgccatcaa tatcgacagc aaccagtttg atagacatgg
    42481 catcctcctt gtttttttgt ggtttatctt aaaaatgttc tccctcctat cttactaaaa
    42541 ataggtgctt ttgtcatggg atgggaaagg aaacttaagg aaaaacgaga gaaaacgttt
    42601 tagtttagct caatcgcctc tgtagtaact aaaaagattg aagaaagtac tctttcttca
    42661 atcttagaat ggagacaaac ccagtttgat gctcaaaaag catgaactgc tctgctgatt
    42721 tgacaactga tttcttattt ctgcgtgtga cgtgagccaa aacagctgct ttttgctgtg
    42781 gcaaaagtgg tgtcaatact ggcagtgacg ttacgcggaa tttttgagac cctaggctca
    42841 aaaataaagc atagaattcc aaaggaagtc gctgccataa gcatcaccta agaaaagtat
    42901 caaaaaagac tttttctgca atcttaaagg gctttactga ctaaagtgaa aatgcccatt
    42961 ggaaatataa ctcataaaag tttccttgct aggagcaaag aggtcatcga gctctaacat
    43021 ttcctttgga aaataaaagc gacggtctcc gtaggttgtc cctgttaatg ctttgacaat
    43081 aggagataac tgagataatt cagcaaggct cccgtctttt tgcatcattt caatctgagt
    43141 tcttggattt tcgagctctg gtcgataaat atcataaggc aggtcgaagt tgatatggat
    43201 accggtgtaa taatctggat caaagccaac tgattcgacc aattggcgca agcgttctaa
    43261 ctctccttgg gaatcttggt caaaggtaac agacttcaga atttttcgat taataaagcg
    43321 actggccaaa tctgataaga tatggtcttc gcttgccatc cagacttgga agtaagtatt
    43381 catgactccg tcatctaggg ctatataatc tgctaaatta gccttctttt caaagaaggg
    43441 gatgagtcca ggagctgttt tttggaaata agcctgttgc tcaggatata agtgttgggc
    43501 tcttttgagg agattttgta agatgagctc aacagcacgg ctggcgggat gaaaatagac
    43561 ctgcatgtac atttgaaaac gactgacaat atagtcctcg acagcatgca taccactatg
    43621 ttcaaagaca atgccatctt caacaggtcg aatcacacgt aggatgcgca ttaaatcaaa
    43681 ctgaccgtaa ttggcagcag aaaaataaga atctcttaaa aggtaatcca tacggtcgca
    43741 gtcaatctgg ctggaaatca gttgcacaac ttgcttgtta ggataagtat gattaatcac
    43801 gctggcaact ttgtctggaa aatcaggagc atgacgcacc aaaatggcat tgatttctgt
    43861 ctcaggattg gtaattatct cctgagtaaa ggcctcgtga tccgtatgaa aaagaacctc
    43921 aaaggtatga gaataggctc catgaccaat gtcatgtaag agggcagccg tcatagtgac
    43981 cagactttca tctttattcc agatatcagc gtatttctct tcaaaaatag ctgtcacccg
    44041 acgggcaatt tcgtaaacac ctaggcagtg agaaaaacgg ctatgttctg cgccgtggaa
    44101 ggtgaaagct gttgtaggga cttgtttgat gcgtcgtaag cgttggaatt ctttggtatt
    44161 gataaggtca taaattaatg gattatcaat gtggatatag ttgtgaacag ggtcacgaaa
    44221 tactttttca ttcataattt ttattatatc aaaaattgat aaaataagga gaaattgata
    44281 gaataaacag acgagcttag aatagaaaga agagttatga aattacagtt aaccaaccat
    44341 attcgctttg gagatgagac agagattatt caagaaattc atgattgtga gtggcgagaa
    44401 aaagggggct atcagtacct catctatcaa aacactgaca aggaaaaggt tgtcatcaag
    44461 tacaatgaga cagaactgac catgagccgt ttttccaacc ctcagtcaat catgaaattt
    44521 tttgcgggca agaaggtcct gattgctcta cctacgccga tgggggttca acaatttttg
    44581 acagatacca gtcattacca cttagattgt tcttgtcaaa aattggacct tcattatcat
    44641 ttgcttcaag ctcaaacaga aatgctattt gcaagctatc atcttgagct gagttgggat
    44701 taactaaaaa gatagcagta aatcatctga ttagggatta ttcttgtttt ttagtcaggt
    44761 ttttactata atggttatta tatcaaggga gtagcagacg gctagccgtg attgtatcgt
    44821 caatacggaa tttcggtttc cggtacaatc ttaaacagcg agacttgttt aagaaaaata
    44881 aacaggtctt tttatttgaa caactaaaat aaaaagacca aggaggtact aatttgtcta
    44941 aagaacaaag acatgaagca ttttacacgc aaagtgaaga gaccgtactg gctcaattag
    45001 agaccagtcg cgaaggtctt acgtctgccc aagcaaaaga gcgcttagca gagtatggtc
    45061 gtaatgagct tgatgaaggc gaaaaacgaa gtttatttat gaaattcctt gatcaattta
    45121 aggatttgat gattattatt ttgattgtgg cagcccttct ttcagttctt acagagggga
    45181 tggaaggttt gacagacgcc attattatct tggctgttgt tatcctaaat gctgcttttg
    45241 gtgtttacca agaaggacaa gctgaagctg ctattgaagc cttgaaatca atgtcaagtc
    45301 cactggctcg tattcgccgc gatgggcatg tgactgagat agactctaaa gaattggtcc
    45361 ctggagatat tgtcttgcta gaagcgggag atgttgtccc tgctgatctg cgtcttttgg
    45421 aagctaactc cttaaaaatc gaagaagcag cgcttactgg agaatctgta ccggttgaaa
    45481 aagacttgtc aacggctgtt tcagaagatg ccggtattgg tgatcgcgtc aatatgggat
    45541 atcaaaactc aaatgtgaca tatggtcgtg ggattggggt tatcactaac actggcatgt
    45601 acaccgaggt tgggcatatt gctggtatgc ttgctaatgc tgatgagaca gatacaccat
    45661 tgaagcaaaa ccttgacaac ctttctaaga ttttgactta tgcgatcctt gtgattgcag
    45721 cggtgacttt tgctgttgga gtcttcttgc gtggtcaaca cccgcttgaa ggcttgatga
    45781 cttcagtagc gcttgctgtt gcagctattc cagagggact tcctgcgatt gttactgttg
    45841 tgctttctct tggaactcaa gtacttgcta aacgtaacgc cattatccgt aaattaccag
    45901 ctgttgaaac gctaggatca actgaaatca ttgcttctga taaaacgggt accttgacaa
    45961 tgaatcaaat gaccgttgaa aaagtttata ccaacgggac actccaaagt tcatcagctg
    46021 atattgcttt tgacaatacg acacttcgtg taatgaactt tgctaatgat actaaagttg
    46081 atccttcagg gaagttaatt ggtgacccaa cagaaacagc tttggtagag tttgggttag
    46141 accacaattt tgacgtacgt gaggctatgg tggcagaacc tcgtgtggca gaactgccat
    46201 ttgattctga ccgtaagttg atgtcaacca ttcataaaca agctgatggc aaatatttca
    46261 tcgctgttaa aggtgcacca gatcagttat tgaaacgtgt cacacagatt gaagaaaatg
    46321 gacaaattcg tcctattacg gatgctgata aaaaaaccat tcttgatacc aataagagtc
    46381 ttgccaaaca agctcttcgt gtcttgatga tggcttacaa atattctgat gcccttccaa
    46441 cactggaaac agaaattgtt gaggctaatc ttgtcttctc tggtttggta gggatgattg
    46501 accctgaacg tcctgaagca gcacaggctg ttaaagtagc taaggaagct ggcattcgtc
    46561 caatcatgat tactggtgac caccaagata cagcaaaagc tattgcgaaa cgtcttggta
    46621 ttatcgaaga agatggcgtt gatcatgtct ttacaggtgc tgaactcaac gaattatcag
    46681 atgaagagtt ccaaaaagtc tttaaacaat actccgtgta tgcccgtgta tctcctgagc
    46741 ataaagttcg tatcgttaag gcttggcaaa atgaaggcaa agttgttgcc atgactggcg
    46801 atggggttaa cgatgcacca tctcttaaaa cggcagatat tggtattggt atgggaatta
    46861 caggtacaga ggtttctaag ggagcttctg acatggttct tgccgatgat aattttgcaa
    46921 ccattatcgt tgcggttgaa gaaggacgta aggtcttctc aaacattcaa aaaacaattc
    46981 aatacttact ttctgctaac atggcagaag tctttaccat cttccttgca accttgtttg
    47041 gttgggatgt gcttcaacca gttcacttgc tttggattaa cttggtaact gataccctac
    47101 cagctattgc tcttggtgtt gaacctgctg agcctggtgt gatgaaacac aaacctcgtg
    47161 gacgtaagtc aagcttcttt gatggtgggg tgaaggaagc cattctttac caaggtgcct
    47221 tccaaaccat tttggtgctt ggggtttatg gttttgcctt gatgttccca gaacacacaa
    47281 gctatcatga tgtccatgca gatgctttga ccatggctta tgtgaccctc ggtttgattc
    47341 agttggtaca tgcctacaac gtgaaatctg tttaccaatc catctttact gttggattgt
    47401 tcaaaaacaa attgttcaac tattctattc cagtggcctt tgtagcatta atggcaacag
    47461 ttgttgttcc tggatttaat caattctttc atgtgacaca cttgacgatc acacaatggt
    47521 tagtggttat tatcggaagt ctcttgatgg ttgttcttgt tgaattggtg aaagctgttc
    47581 aacgatcact tggtcaagat gaaaaagcaa tttaatagac gctaaaaggt ttgagacaat
    47641 tgtctcaaac ctttttttat aatcgttaca atgataagga ctattggtat gcctgacatt
    47701 aaaaagttga ttcttgccaa ttgacttgac agtcaaaaat ttgttgtttg gcttcttgac
    47761 tgtgaccttc aatatcatcg attaaaatct tagtagcctg ttcgccttct tcataggcgg
    47821 gttggataat agttgttagt gttggtgaag aaaattttgt ccactcaatg ttatcaaatc
    47881 ctactagtcc aatctctggt atattaaatt taagagactt catagctgta aatacttttg
    47941 gaagagccca acaattgggg acaaaaacca aactcttttt agtcagtgat ccttgcaaaa
    48001 actgagcaat tgcctctgaa gaagtctgat tttcatcaat aatcatttct tgatgagtaa
    48061 gatgattagc ttctaacaca tcaatgaagc ctgaagcgcg ttcaatacga gtgctaagta
    48121 aattggggtt acccgtgatc atgataaaat gttcataacc tttatcgata cattgttgaa
    48181 tggtatcata aacagcatca taattattag ttttgaccca gtttgtgcga tgttcgtaaa
    48241 gttggctatc aaaaaagaca accttctttt ttttaatatc gataatacgt gaatattttc
    48301 taaagttaga agttggttga ataataaaac catcaacacc aagattgagc atcttttcaa
    48361 tgagttcatc ttcgcgagaa gggtcgtagt tgctgtttcc gatgataatt tggtaaccaa
    48421 attcctgggc tttgctttca attcctttga caatttggtt tgaaaaactg tttgtgatgt
    48481 cacctataac aacaccaatg agtttagtcg attttgcatt gagacttcta gcagcaatgc
    48541 tcggtttata attagtagct ttgatactct cgctgatgcg gtttttagtt tcttcagaca
    48601 tcttgtcaaa tctgccattt aagtagaaag aaactgttgt ttttgaagtt ttcgctaatt
    48661 cagcaatatc tttgatggtt actttgcgct gcattgcata cactccttta aaatagtaat
    48721 ggttagtcat attataacat aaggactcgt aaaagattta gtgtttcaat cgaataatct
    48781 cattcgtgat atggttgata acaaccacct ttcctctgat tttatgacta tttaggagaa
    48841 ctagtttttc tcctttaatt aaatcctctt ggagaacaca gatactgtag tcaaactgct
    48901 ttccttttaa atgccaggaa agggcagtct caattgggtt gcgtttgcct gtttgaagtg
    48961 gtgttaaggg agtaactttg gtatcgtcag ggactaatag ggtactggtg caacccttgt
    49021 ctttaaaggg ttttcgtttg atgagtttgt gactagtcag gtattggttg tatttttttg
    49081 acaaaatcgt ttcttcgata gtgaaagggc agtcactgat tagtctgagg tcactaaggt
    49141 gatctgtctt tacgtctaag tgattatcaa gaataaattg actgacaaga cagtggttgc
    49201 cttgagcctg tatcgtatca atgataagaa aaattcctgg tggtaagatg agaatttgta
    49261 ggtcatgttg gtagttgttc ctatcagaga attgcgtctg gtagctacct tcaataaagt
    49321 aaacgtgtcc attttgtcga aggtgacaat aattggattt ggggtaagaa aggtaagccc
    49381 aggagctatc aatctgctca ggtaattgtt cttctaagaa ggcggtagaa tgatggctag
    49441 cgctttttag ggcatagcgt aatggttctt ctttgtaagt gtatcgccca gcatcacaga
    49501 aaagtggttg tcctttataa tagagacaga gactattttg gtcgctatgg gtatgggaac
    49561 taccgatggg cccatttttg aaaaaaagat aataattttc ttgattgatg gtaatgtgcc
    49621 cggaatgttc aaagtgatgc gcaaaagttg gtaaggtttg gacgggtaac tgttcaaaag
    49681 tgtggacacc tttttctcct agaaggagaa gactatcgat atcaagtgtg ggaaaagcag
    49741 cagcttttaa gtgtggttct tcaaggatag tggctgcaag cgttagaata tctctggtat
    49801 ctgtaacatc gctatcacca agagggattt gtttatgatc tggaccagtc attttgagga
    49861 gataatcact catggcaagc aaagtaggtc taagctgtgg aagataatca gggactagag
    49921 cagttaattc cagaagggct ttgagtactt ccacatgata catggttgat tgttcaaatt
    49981 gactgccgtc ttcgagaatt tgtagtgcga tttgttgcgt caattctttt ctagcgaaag
    50041 ctgttgctgc agcaatatca aggtcagaac caaagtaggc atcagctaat aaaatcgcag
    50101 tggtttgcaa gattccccaa ttgctgaggc tgtatttatc aaggtagttg gcatggagaa
    50161 attgaagttg tttttccagg gaagctagga tgaggctttc ctcttgcttg gttaaggcgt
    50221 taaaaagatt aaggtaaatc aaacatttga cccaagcaaa acaacggatg ccagtatcta
    50281 aggttctagt agctaacccc ttagggtcta aaggaatagc tgattcaatc caattgagga
    50341 tgaaaccttt agctgttaag agataccgtt catctctttc aacaaggtag acgaggatta
    50401 atttttggag ataggtctgt cgatttaaca taaagttcca ctcaggatca tctatgacag
    50461 cctcttgcca agtaatggga tctaagtggt aagggatgtg gcagggctcc atatcccaat
    50521 tatcttcaaa taaaaaggta ttggttaaga gtaggtcagc tattcttttt tgatcagcat
    50581 agctgtcagt ctgatagtct agcaggtaat tcctgcaaaa gtctggattg actgtttctt
    50641 taaagcgtgc gaaggcaaaa aacataggac atttcctttc caaaagaaaa gagacctcat
    50701 catgtgctta ggaactattt ccctatgctc ataacaggtc tctatgaacc attaagctaa
    50761 aatacccaac caactgccaa taacaccaat gataacagtt aaaatgacca atttgtaggt
    50821 tgtccatttt ttgtttttaa taaggtaata catgagtaag gtaaagagag ctggtaaaag
    50881 tgcaggggca atcttatcaa gcattccttg aatagtcaca aatttttgtg ctgtattggc
    50941 cgcatccacc ttgccagcgg caaaagtaat gggaacagta attttaacag aagtagctgc
    51001 tagtccagcg ataacggtaa cgccgacaat atttgccatg cgcgacacaa ccgccatttg
    51061 ttcacttaat ttatcaataa agcttgtgcc gaccttgtag ccatagagtc cagaaccaat
    51121 tttaatagcg gttaggataa tattcatggc taggaagaag aggattggtc ccaaaaccag
    51181 accatcacta gctaaggaag ctgcaatcgt tgaaaagagt ggcgccaagc aaaattgtga
    51241 taaggagtca ccgataccag ctaaaggccc cataagtgcc attttgatgt ttcgggtttc
    51301 ttcttcaggg cgattatttt ctaacatgac caagtgcaga ctggtgatga aaggaaggaa
    51361 gtgaggatta gtattgtaaa actcacagtt atcttctaaa gcttgatata agcccttttt
    51421 atcactgcca aaatgttttt tcaaggcagg atagatgaca ttggcgtatc cgataccttg
    51481 gtaattattg taattaaacc cattttgtag gaagaaagct ctcagagctg ttttgaggta
    51541 atctttcttg gttaatttat tagatccagt catcttgttg gcctccttgg acagttgttg
    51601 catcgacttg tttaggtttg ttgtaaaatt cattcaaggc gaaaatgata ccaataatgg
    51661 cgataccaat ggttggaatt tggaggtagg ctgcacaaac ataaccaatt agtacaaaag
    51721 gaatcaattc tttcttggcc ataacagata agatcatggc aaatccgata gcaggtaaca
    51781 ttttaccagc gacagtcaat ccattgagca agacaggtgg gatataatca accaagtgaa
    51841 ggagagtatc cattgacaag gcacctaata aaccaaggcc taatccgata aaagcgaaag
    51901 cccagatagt gccgttggca gcgaatttga agcctctaat attgcctttt tgcaattgtt
    51961 ttttagcggt ttcgggagcg ccagcaaaag ctgtataggc gaatgtttga aggaattgga
    52021 tggcaactgc gattggtgtt gataaggcta gtgccgcttc tggggtgact ttaccagcac
    52081 tggtaatagc catcaaggta ccaaagatac cagggccgat aggattagga ggaacggtac
    52141 caccggcacc cactccaaat cccatataag ctaattcgga gatagctccc atgctaagtg
    52201 cagttggcaa gtcacctaag ataatcccta caccaaaaga cagaataata caacggttgg
    52261 tgtagatgcc aagtaacatt ccgctgaaac aaaaggctgt ccaaagacca attaaaagtg
    52321 cctgtaacaa attgatatcc atatcaatct cctttattca ttaaatataa tctaagatgt
    52381 caacgtcaga ggcgctattg ccagctggag ttgttttggt gttaaaaacc acgtggtggt
    52441 catgggctaa gcaacgaata gcagacttgt ctgtttctcc cagcgaaata aactgggtaa
    52501 tcgcaacctt atcatcagtt ttatgaatat taccgatatt gatttctgtg atgggaacac
    52561 ccccttcaac taggagtttg gcatcttgca aatctttgac cacgatgaag atactttgag
    52621 caggacttgc tttatgaatg atgtcaatca ctttttgaat ggagaaaaaa cgaatggcaa
    52681 tactggatgg aataactgtt ttcatgaggg attgttgaat cttatcttca gaaaccgcat
    52741 cgttagcgac gataacggtg ttgcagttga ggaatttgac ccataattgc ccctgtccgt
    52801 gaatcaaacg ctcatcaact cgcgtcatga taatgtttgg ttgtgtcata aaatctcctt
    52861 tttaaatgta ggtatcggtg tttgttacca gtaagggttc cagtctttgt agaaacgaag
    52921 cagagcttca agatagtaat agtctcccca gatatttccc tcgtcaaccc cttttccaga
    52981 gtgccaagaa tagactccgt gaagcagtag aggagcacca ggcttgagat ctttgttagc
    53041 ataatcctta atcaaggctc ttagcatgct gtgcatggca gcttcatatg tttttttatc
    53101 aggatcatga tctggtaagg tttttaacat ttcatgaata ccacacacag caatggcggt
    53161 tgctgaacta tcacgagact gctcgctacc atctccaaaa attaaatccc agtaggacac
    53221 ctggtcttta ggaagacggt tcaagaaata atgggtcatg cccttgaaga gttgaatgag
    53281 ttcaggttct tttaggaaac gataggtcaa aggaatacca taaatgcccc aagcttgccc
    53341 tctggcccaa gcagaatcat cgctataacc ttgtcgggtg acccctttaa caggatcacc
    53401 tgtttctgga tcaaagtaga aggtgtggta agcagaggcg tcatctcgga tgacatgatt
    53461 ggctgaggcg tagaaatgat tgatcgccat gtcacggtaa cggttgtctc cagtttcttg
    53521 gctagcaaaa aagagtaatt ggatgtttag gagacaatca atgattaaac ggtaatcttc
    53581 ttttttaccc agttctcccc aggcctgaat aaagccgcct ttgtcttgat agcgttggac
    53641 taatttgtcg gctgctttca aagcagcttc tctagactca ggtgttttta aaagtttcca
    53701 ctcagccatg caagaagggg tgtaaagaaa gcccaaatca tggtgatcta gctcaatgtc
    53761 tcttgttact cgatctagga aagaaaggtc atttgcttga gccagagctt taatagcatc
    53821 atccccactg tattcgtaag ctaaccaaag gcaacctgtc caaaaggcat tggtccattc
    53881 tgtattatcc ataatggcat attggttatc tttggtagct ggcgttggaa agtcttcttt
    53941 aaaatagtcc atattaagcc gaacttgttt gagggctaag tcaagggcct gagtaatgtc
    54001 ttcttggctt aggaaatctt ctttggtaaa tcgttcaggc tgcttgatag gttcaagagc
    54061 aatggttttt aaaggtcgtg ccattaaatg cctcctaact catcgtctgt cgcaccgtct
    54121 tcttgctgag aaagagtttt ccagtcaaca atgccttctt tagaacatgt tataagtcct
    54181 gatactaagt cgtcaaaaga agctgctgtt tgtcttgcaa aactagcttc aatcagcatg
    54241 gctaagttaa ggccagaaag aacattacac gtcgtgtttg gaagagattc cattaaggtt
    54301 gcagcgactt taaaaggggt acctcctaga aggtcacaaa gaactaaggt ttcctcttct
    54361 gggattaaag cacgagataa ttggtcctgc acatcagcgg cggtcatctc agtagtaaaa
    54421 tcaattgcag ttaccttttc ttgtttgcct gcgatcaatt ctaaggctga aacaatacca
    54481 ctcgcaaaat gtccatgtcc cataacgata atagcaatca taaataaatc tccttcggtt
    54541 taccggttta ctcaaaaata ttgtagcgct ttcaaaattc tttgtcaata cttttttaaa
    54601 aagatttttg aaaaagaaaa agtgaacggt tgtgctaaaa aagaatcaaa aatggtcttt
    54661 ttttgtcact atttaatgta gaaaagtctt aatggctatt aagtatagga gaagactaaa
    54721 caagaatggc agtttggata agagcactct tttaaatttt gaaccgtttt cattaaaatg
    54781 attgacaaaa ctagtttact ttgttatagt cttggtaaac aggtttactt aatttaataa
    54841 caaaaaggag aatcctatgg aaaatatgtt ttcgttacaa ggtaagattg ccttgattac
    54901 cggagcatct tacggtattg gttttgaaat tgccaaagcc tatgctcaag cgggtgcaac
    54961 tattgtgttt aatgacatca aacaagagtt agttgataag gggttggctg cctatcgaga
    55021 gttagggata gaagcgcatg gctatgtttg tgacgtgact gatgaagctg gtatccaaca
    55081 gatggttagt caaattgaag atgaagtagg tgctattgat attttggtca acaatgcagg
    55141 tattattagg cgtacgccga tgcttgaaat ggccgcagaa gattttcgtc aagttattga
    55201 tattgattta aatgctcctt ttattgtgtc aaaagctgta ttaccatcaa tgattgcaaa
    55261 gggacatggt aaaattataa atatctgttc tatgatgagc gaattggggc gtgaaacagt
    55321 tagtgcctac gcggcggcta aaggtggctt gaaaatgtta accaaaaata tagcctctga
    55381 gtttggagaa gccaacattc aatgtaatgg gattggtcct ggctacattg cgacgcccca
    55441 aacagctccg ttgagagagc gacaagcaga tggtagtcgt catccttttg atcaatttat
    55501 cattgctaaa acaccagcag cacgttgggg gacaacagaa gacttagctg gtccagctgt
    55561 ttttctagct agcgatgcca gtaattttgt caacggccat attctttatg tcgacggtgg
    55621 cattttagct tatattggaa aacaacctta atcacacact agaaagagat tttatatgaa
    55681 aattgcatta attaatgaaa atagccaagc ggctaaaaat ggtatcattt acgatgccct
    55741 taccacagtg acagataaac acggctacca agtctttaac tatggtatgt atggcacaga
    55801 aggtgaaagc cagttgacct atgttcaaaa tggactctta gcttctattt tattgaccac
    55861 taaggcggct gattttgtgg tgactggttg tgggacaggt gttggagcta tgttggcctt
    55921 gaacagcttc ccaggtgtta cctgtggttt tgcgagtgag ccaacagaag cttatctctt
    55981 ttctcaaatc aatggtggta atgccttgtc cattcctttt gccaaaggtt ttggttgggg
    56041 agcagagttg aatttgacct taatatttga acgcctcttt gcagaaccaa tgggtggtgg
    56101 ttaccctaaa gagcgagcta ttcctgaaca gcggaatgca cgtattttaa gtgatctgaa
    56161 aaaaattact tacagagatt tgttggcaat tgtcaaagac atcgaccaag atttcctcaa
    56221 agaaacgatt tctggcgctc atttccaaga gtacttcttt gccaatgcgg agccgtcaga
    56281 attagtcact tatttgaaat cagtacttga acagtaattc cattttgacg aggaaaggag
    56341 gtcacatgtc taagttatta ttggttggtg aaccgctgat tcgcgttagc cccaatcagt
    56401 ttcagccttt gaccaatgcc tgcgaggctc agcttttttt cggcggttca gaagttaata
    56461 ttgcaagaac tctaggcggt tttggcttag aagcaaggct atttacggcc ctaccagata
    56521 atcctgttgg tcacgctttt catcagtttt tgaagcaaag cggcgtggat atgtccttga
    56581 cggcttggca aggtcatcgc gttgggctat attaccttga aaatggcttt ggctgtcggg
    56641 ctagtcaggt ttattatgac cgctgtggct ctagcttttc ggccttagat aaggatagtc
    56701 ttgatttagc tgccattttt gaaggcatta gtcactttca ttttagtggg atcagtttgg
    56761 cgttgggcaa aaaaactcag gacctgattg aggtacttgt gagagaagct aagaaaaggg
    56821 atatttgtat ttcctttgac cttaacttta gatctagtat gattgccgta gctgatgcta
    56881 aacgactctt ttctcacttt gctcaatacg cggatattat ttttggcatg gaacctttgc
    56941 tgttagacag tgacgatttt gacatgtttg atagaaaaaa ggcagatact acgacgatta
    57001 gagaacgtct ggcaggactt tatcagcgct atcagttaca agctatttac catacggagc
    57061 gttcaaatga tgcccaaggc agtaatcatt tcaaagctta tgcctatgat aggcagtttt
    57121 acgaatcctg tgaagtgacg accccagtct tgcaacgggt tggaagtgga gatgcttttg
    57181 tggcgggttt actttatcag ttgttagaag gtaacgaaaa gcagcgcaac cttgattttg
    57241 ctgtggcaac agctagccta aaatgtacag tagctgaaga tcagctctat cacagtgtcc
    57301 aacaagtaga agcagtctta gctaatcaac gagatatcca gaggtgatga tatgggaaaa
    57361 atagaaatct taaccaaact taaggctaat cggcttgtcc tagttgtacg aggagagtct
    57421 agtgaggaag ctttagcttg cagcctggcc agtattgaag gtggcattaa gacaattgaa
    57481 gtcacctata ctaacccctt tgctagtgag gttatcggtc aattagctga acgcttcaaa
    57541 gaagatcctg aggtattgat aggtgctggg acagttttgg atgatgtcac tgcccgccaa
    57601 gctattttag caggagcaca gtttattgtt ggtcctaatt tcaatcgagc agtggctttg
    57661 atttgtcatc gttatagcat accttattta ccaggttgta tgacggttaa tgaagtggtt
    57721 acagcattag aatcaggggt tgatatggtc aaaatttttc ctggttctac tgtagggata
    57781 tcctttattc gggcaatcaa atctcctttg ccacaagtag aggttatggt tacaggcgga
    57841 gtttcttcag ataatctcaa agactggcta gctgctggag tagatgttct aggcatagga
    57901 ggcgagttta atcagttagc gagccaaaaa caatataacc taatcactaa gaaagccgct
    57961 cattatatca aaagtttgcg acaataatct aaaaaacgtt tttaccttgg ctttagtgct
    58021 agtaaaaacg tttttttatc attcattcaa ttaatatgct tctgctcatg tttttccaga
    58081 tagtatagat ataagagcag ctaatttaac aagatgagcc tgtcgtttga tatataggat
    58141 ataaactttt tatgatcaaa caaaagtaat accttttgaa ttcgttagta ttgatctgat
    58201 ctaaagtgat atcacttaga atggactagc tgtacagctt ttacagcaac ttatgctaaa
    58261 atagaaaaaa ggagaaatgt tgatgattaa aggaattatt tttgatatgg acggtgtttt
    58321 atttgataca gaaccttttt atctgaggcg acgagaagat ttttttaaga caaagggaat
    58381 tcccattgat catttgaact ctaaagattt tattgggggc aatcttcaag aattatggaa
    58441 agagttgtta ggtaaaaata gggatgatgc tatcgttaag gcaattacaa ctgactatga
    58501 cgcttacaaa caagcgcata agcctcctta tcaaaaactg ttgattacag aagtgaactc
    58561 ttgtcttgaa cagttggaaa aacaaggtat taaactggct gtggcatcaa actcgaagcg
    58621 tcaggatgtt ttgttggcgt tggagacaac gcaaataaaa gattattttg aaataatcct
    58681 agcgcgtgaa gatgtttcta gaggcaaacc ttatccagat atttataata aagcagtaca
    58741 aaaactagga ttacaaaaaa aacaactgct tgtagtagag gacagccaaa aaggcattgc
    58801 tgccgccaaa gcagccaatc tgacagtttt tgccattacc gactaccgat atggcattga
    58861 tcagagtcaa gctgatcaca agatagatca tttaggacaa ctgtgtgtaa aaatcggttg
    58921 ttttggatcg tgaagtaacg caactaactg atcatgatac ttcaagacag ttaagaatac
    58981 gtctaggact ttctacagac caataacaag aatatgttta tgtgttttta ctgtttttta
    59041 gctacctatt tacaatatga cactgaaaag agtactatgt ttaagttatt atcaaaaaaa
    59101 acgtcgcata agatcaccta gaaaaggatt atgatttttg tgatttggat gcgatcatta
    59161 gtcgtcgacc atcttcattt ggcaggaggt atgtttaacc gtggtcatta tttggatttg
    59221 tttttagatt ggctagtgag taaatataga aggatcataa tactgctttg acaaaggcag
    59281 tatctgagtc catgagttgc acgggtaatg tgactcggtt ttggttaggt ataataatat
    59341 ttggaagtgt tatgctgctt gtcttcgtag gtccattgat tatagtcaga cttactttag
    59401 agctgagctg actgtctaga caagacgtga tggagatgtg atttctgacc aagtagaggt
    59461 aaccagaaaa gggactttta cgatggaatt gaatttactt gttgcattct tgtgcatgtt
    59521 aagagagaaa acccagataa atcaggaagt aaaatggtta tgtttgatta gaattgtcct
    59581 tctttttcct tgaagtctta acttattttg attatgatag tagtatgact attaaggcag
    59641 aaattaaggc gctcgccaaa gaaattggta tctctaaaat tggttttacg acggcagata
    59701 actttgatta tttggaaaag tcattgcgtg cttctgtgga agaggggcgc aattcaggat
    59761 ttgaacataa agtcatagag gatcgtatct acactgaaag gcttttagaa tcggctaaaa
    59821 cgattatttc aattggcgtt gcttatcctc acaaacttcc tcagcaacct caaaaaacac
    59881 cttataaacg tggaaaaatt acacctagtt cgtgggggct tgattatcat tatgtggtcg
    59941 gcgaaaagtt agacagacta tcaaaaggca ttgaagagct gtgtcgagat tttcctttgc
    60001 aacaaaaagc aatggtcgat actggagctt tagttgatac tgcagttgcc caaagagcgg
    60061 gtattggttt tataggaaaa aatggtctag ttatttctaa agaatatggc tcttatatgt
    60121 ttttgggaga attaattacc aatttagaga tcgagccaga caagcctgtc gattatgatt
    60181 gtggtgactg tcgtcgttgt ctagatgcct gtccaacttc ttgtttaatt ggtgatggct
    60241 caatgaatgc caagcgttgt ctatcatttc aaacccaaga taagggaatg atggacatag
    60301 agtttcgaaa aaagattaaa acagttatct atggttgtga tatttgccaa atttgctgtc
    60361 cttataacaa gggtataaac aattcaccag ctacagagat tgatcctgag ttggctcaac
    60421 cagaattaat accatttttg agtttatcaa atggaaaatt taaagaaaaa tttggtatga
    60481 ttgctggaag ttggcgaggt aaaaatattt tacagcgtaa tgccattatt gcgctagcaa
    60541 atgctcatga taaaactgca gtggtcaaat taatagagat tattgataaa aataataacc
    60601 ctattcatac tgcaacagct atatgggcat tgggagaaat tgtcaaaaaa ccaaacgatg
    60661 agatactggc gtttatgagt catttaacct taaaagatga agatagccga aaagagttgg
    60721 aattaatccg tcataaatgg caattttaag ccttttatgg tatttttaag aaccttatga
    60781 taaaataaaa cagattaaca aagattggag aaatctcatg gaagtggctg aaattcgcca
    60841 aaaaatagta gaaaataaag agaagttgac tagcttcagg aggtctcttt gacttagatc
    60901 gtttggaaga ggagattgct cttcttgaaa atcacatgac tgagccagac ttttggaatg
    60961 acaatattgc agcgcaaaag acatctcaag aactaaatga gttaaaaggt aagtatgata
    61021 ctttccataa tatgcaagaa ttatctgacg aaacagaact cttacttgag atgcttgacg
    61081 aagatgattc tttgaaagaa gaattagaag aaaatctaat gcagctagat aagataatgg
    61141 gtgcttatga aatgacgctt ctcttatctg aaccctatga ccacaataat gctatcttag
    61201 aaatccatcc tggttcagga ggaactgaag cgcaagattg gggagattta ctcttacgaa
    61261 tgtatacccg ttttggcaat gctaatggtt tcaaaataga agtattggat tatcaagcag
    61321 gagatgaagc tggtattaaa tcggttaccc tctcttttga aggccccaat gcttatggtt
    61381 tgttgaaatc agaaatggga gttcatcgcc tcgttcgtat atcacctttt gattcggcta
    61441 aacgtcgtca tacctcattt gcttcagttg aagtgatgcc agagttagat gatacgattg
    61501 aagtagaagt acgtgatgat gacattaaaa tggatacttt ccgttccgga ggagctggtg
    61561 gtcagaatgt caataaagta tcaacaggtg ttcgtttgac gcatattcca actggaattg
    61621 tggtatcgtc taccgttgac cgtactcaat atggaaaccg cgatcgcgct atgaagatgt
    61681 tgcaggctaa gctatatcag ttagaacaag aaaagaaagc acaagaagta gatgctctca
    61741 agggtgataa aaaagaaatc acttggggaa gtcagattcg ttcttatgtt ttcacccctt
    61801 atacgatggt gaaggatcat cgtactaact ttgagcttgc tcaggtagat aaggttatgg
    61861 atggagagat caatggcttt attgatgcct accttaagtg gcgcattgaa gactaaaaat
    61921 aataaaggag aaacatggca ctaatagaaa tgtctggtgt tactaaaaaa taccgccgct
    61981 caacgaccgc cctcagagac gtcaatgttt ctgttaacca aggtgagttt gtttatctcg
    62041 taggcccatc aggtgctggt aaatcaactt ttatcaaact cctttaccgt gaagaacaac
    62101 tgacaactgg taagctatat gtgggtgaat tcaatttaac taagctaaaa gcacgtgatg
    62161 ttccgattct tcgtcgtcac atcggagtag tttttcaaga ttacaaactg ctaccaagaa
    62221 aaacagtctt tgaaaatgta gcttacgcca tggaagttat tggtgaaaag cgccgccaca
    62281 ttaaaaaacg cgtgccagag gtactcgatt tagttggctt gaaacataag atgcgttctt
    62341 ttccaagtca gctatcagga ggggagcagc aacgtgtggc cattgcgcgt gcgattgtta
    62401 acaaccctaa attattgatt gcagatgaac cgacagggaa tttagatcct gagatttcat
    62461 gggaaattat gcagttactt gaacgtatta atgttcaggg aacaactatc ttaatggcga
    62521 cacacaacag tcatattgtg aatacattcc gtcatcgtgt tgttgctatt gaagatggtc
    62581 gcatagtacg tgatgaagaa aaaggagatt atggttacga tgattagata ctttttccgt
    62641 catatttggg aatccattaa aaatcttaaa cgcaactttt ggatgacatt tgcttcagtt
    62701 agtatggtgg ctgttacatt gactttagtt ggtgtttttg cggcgacatt gttgaatata
    62761 cagcgtgttg cttcgggtgt tgaaaataat gtccatatca atacctactt acaagttgat
    62821 tcaactgatg ctgcaaaagt tattcaaaat actgccggtg aacctgttaa taacgataac
    62881 taccacagtg tttacgacaa aattgctcag ataaaaggtg tcaaaaagat tacattttct
    62941 agcaaggatg aacaattgaa aaaattgcaa gaaaccttag gtgatgtttg gaatatgtat
    63001 gaccaagaca ctaatccgct ccaagatatc tatcttattg agacccagac gcctaaacaa
    63061 gttaaggcga tcactaaaaa gatcagaacg attgaaggcg tagaagccgc agattatgga
    63121 gggattaact ccgataaact atttaagttt tcaacattaa ttcaaacttg ggggctgatc
    63181 ggaacagcaa tgctattatt tgtagctgtc tttctcattt caaacactat tcgtatgact
    63241 attatgtctc gtaaacgtga cattgaaatt atgcggttag ttggtgctaa aaattcttat
    63301 attcgagggc ctttcttttt tgaaggggct tgggttggct tgttaggagc tgttttacca
    63361 tctcttctga tttattatgg atatgatctt gtttataagc attttgcaca agaattacaa
    63421 cgtaataatc tctcgatgta tccgcttgat ccttatgtat attacctgat tggtgctttg
    63481 tttgtcatag gtattatgat tggttcgctt ggttcagtgc tttctatgag acgttattta
    63541 aaattctaaa aaaagcgctg ctgacgaaac gtagcgaccc tcaaaagttg gacctcttat
    63601 gttattccaa ggacctcgtt ttgtattgca caggactggt ccttttcatt ttgttttgat
    63661 tcatttgttt atttgtaata ggcaatacag tttaaaatag cagtttctaa ggtttcaaga
    63721 gaagaaaagc accccaaaag ttagatgttt gatgtatcta acttttgggg tgtcattcaa
    63781 aatttagtgg ctctttttta gtaaaatact atgatttcag ttttaggata acctcaaaca
    63841 gtatctaaaa tagctatgtc aatgaaaaaa ggggttagca tttttttcgt gacaaatggt
    63901 agtagaagga ccatgcccag gataaactcg gtaatgatta ggtaaggtga atagttcttg
    63961 gcgaatacca gtaatgaggt cctcaaagtt actggtaggt aagtcagtac gaccgatagt
    64021 ttcacgaaat agagcatcgc cagtaacgac taattcatct gagtggaaaa caaatgagac
    64081 tcctccccaa gaatgaccag atgttggtaa aactgtgaat tcaaaaccat ttagttgata
    64141 gggttgcttt aatttaaaaa agttctctgc cggtcttgct ataacagtaa tgatatcatc
    64201 atgacggcct aagccagata aattatcatc tggggaagat agccaagcgg cttctttttc
    64261 tgaaacataa acaggtggat gatcaaaagc atctctgacc aaatctaaac taaaaatatg
    64321 atcatagtga gtatgcgtta agaggatagc cactaaaggt ttttcaaagg atttaatttt
    64381 agcaatgatt tcttggccgt tacttcctgg atcaatgagg ataacagctt gatcattaac
    64441 gaggtaataa gtattttcac cagcaatgtg gtttattgtt ttatagattt tcataaggat
    64501 agtgtaccaa aaaatcaaga ctttgttaaa aaaagagtag cggaaaataa atggcaatta
    64561 gtttcagaaa atatgagatc tcacagcaat ttcttgacac cgttttcata aaggtgtatc
    64621 ataaaagtaa tcaataagcc aagcctaaag ctgaacttag tttaagaaca ctgacttttt
    64681 gagagcaacc taatcggttg actaaaaaat atgaggtgga agatatgtca aaagttgcta
    64741 ttgttactgg tgctggtcaa ggaattggat ttgctattgc gaaacgtctt catgcagacg
    64801 gctttaaaat aggcatttta gactataatg aagagactgc tcaggctgcg gttgataaac
    64861 tatcacctga ggatgctgtt gcagttgtag cagatgtttc aaaacgtgac caagtttttg
    64921 atgctttcca aaaagttgta gatacttttg gtgatttgaa tgttgttgtt aacaatgcag
    64981 gcgttgcccc aacaacccct cttgacacga ttactgaaga gcagtttgaa aaggcttttg
    65041 caatcaatgt cggaggaacg atttggggaa gccaagcagc tcaaaaacat tttagagaat
    65101 taggtcatgg cggaaaaatt ataaatgcaa catcacaagc aggatgtgaa ggaaatccta
    65161 atttgactgt ttatggtggt acaaaatttg cagttcgtgg tattacacag actttggcaa
    65221 aggatttggc atcagaagga atcacagtca atgcttacgc accaggtatt gttaagacac
    65281 ctatgatgtt tgctattgcc catgaagttg gtaaaaatgc aggcaaagat gatgaatgag
    65341 gtatggagca atttgcaaaa gatatcactt tgaaacgctt gtctgaacca gaagatattg
    65401 ctaatgcagt aggcttctta gcgggagatg attcaaatta tatcactgga caaacaatag
    65461 ttgtcgatgg tggtatggta ttccattaaa aatgattaat actgacactg tgggtttcac
    65521 tcacagtgtt ttttaagaag tataaaaaat tatcctatct tggttattgg agtgatggca
    65581 cctttgaggt atagtcatgt tttgttttat agatatagcg tgctataata gacttactat
    65641 gacccagaaa aaacttagaa aatatgcagt agttgacttg gaggctactg gagcaggtcc
    65701 caatgcttct attattcagg ttgggattgt tattatccaa ggaaataaaa ttattgatag
    65761 ttatgaaaca gatgttaatc ctcatgaatc tttggatgag catattgttc atttgacagg
    65821 tattacggat aagcagttgg ctaaagctcc ggattttggt caagtggcgc atcacattta
    65881 tcaattgatt gaagattgta tttttgttgc ccacaatgta aagttcgatg caaatttatt
    65941 ggcagaagct ctttttttag aaggatatga gttaacaata ccacgtgttg atactgttga
    66001 attagcccaa ctatttttcc ctcgctttga aaagtataac cttagtcacc tatctaggca
    66061 gctcaatatt gatttggcag aagctcatac tgctattgca gatgcaagag ctacagctat
    66121 actgttttta agacttttac aaaaaattga gagccttcca attgagtgct tagaaagctt
    66181 attagtctat tcagatagcc tgctatttga aacagcaatg gtcattcaag aaggattagc
    66241 caaagccaaa ccttatgatc ccaacaaata cattaaaatc agacagattc tcttaccaaa
    66301 gggctcaaaa gctctcaagc cttatcaaat atcaaaaagc ttccctatta atatggcact
    66361 attaggtctg gaagaaaggc ctaaacagac tcaatttgct cagttaattg acgaagatta
    66421 ccatcaggga gtagctagtt ttattgaagc tcagacaggt attggaaaaa cctacggcta
    66481 cctgctaccc cttttggcaa aagaagatca aaaccaaatc attgtcagtg tgcccaccaa
    66541 acttcttcaa gaccaattaa tggctggtga agtagctgct attcaagaac aatttcacat
    66601 cgcctgccat agtttaaaag ggcccgccaa ttacctaaag ctagatagct ttgcagatag
    66661 tttggaccaa aatgaccaga accgtttggt gaatcgttat aaaatgcaat tattggtttg
    66721 gctcttagaa actaagacag gagaccttga cgaaatcaaa caaaagcagc gctttgcagc
    66781 ttattttgag cagcttaagc acgatggaga cattaagcag tcttctgaat tttacgatta
    66841 cgatttttgg agagttagtt atgaaaaagc caaaacagcc cgtctcctga ttaccaacca
    66901 tgcttatttt ttacaccgtg ttcaagatga caaggacttt gctagaaaca aggtcttggt
    66961 ctttgatgag gcccaaaagc tgatgctcca attagatcaa ttatcacgtc atcagcttaa
    67021 cctgacggtt tttttacaaa caatacaggc caagttaagc aaccctttac ctcttttaga
    67081 aaaacgctta ttggaaagct tgtcgtttga actgggacaa gtgtcaagtg attactatca
    67141 aaataaagag caccagcttg ctcatgattg gtctcgtata gctggctacg ccaaagaatt
    67201 aacaggagca gattatcaag agttacaagc cttttttgct acctcagatg gtgactactg
    67261 gcttagtagc gaaaagcaag aggagaagcg agtgacttat ctaaacagtg ctagtaaggc
    67321 atttattcat ttccaacagc tcttaccaga aacggtgaaa acttattttg tttctgccac
    67381 tttaaccatc agctcagaag taaccttggc agacctatta ggttttgaag agtatctcta
    67441 tcatgtcatt gaaaaggata aaaagcaaga ccagttggtg cttgttgatc aagaggcgcc
    67501 tatcgtgaca gaagtcagtg accaaatcta tgtggaagca attgcaaaac gaatcgaaag
    67561 cttgaagcaa gagggttatc ctattttagt gctttttaat tctaaaaaac acttgctgtt
    67621 ggtttcagac tatctagacc aatggcaggt gcctcactta gcgcaggaaa agaatggaac
    67681 agcttataat attaaaaaac ggtttgatca aggagagcaa actattttgc ttggtttagg
    67741 ttctttttgg gaaggagttg attttattca agcggatcgt atgattaccc ttatcgcacg
    67801 attgcccttt gataacccag aggatttctt tgttaagaaa atgagtcatt atctattgga
    67861 aaaaggtaaa aatcctttca gagattactt cttgccaatg actattttgc gattaaaaca
    67921 ggctattggt cgcacgatgc gtcgacaaga tcaaaagtca gtggttatta ttttggatcg
    67981 tcgtctcctt acaaagtcct atggacaagt tattttggaa ggtctcggtc aggaattttt
    68041 gatttctcaa caaaattttc acgattgtct agtagaaacg gactgttttc tgatataatg
    68101 gaaaggatct attatatcag aaaaattttt aatggcgtta agcacaatca actaacattt
    68161 aaattagttt gaacttttat tatgctcttt tagacaactg ttcaaatgtt ttcgaattgt
    68221 ttttttgata aggacaataa atgaacaaat ttttggtttt agtaaaccca attactgttc
    68281 ttttcattag tgtcagttgc tatcaaaaca gcttgtcata gttcgtgcga tcagtagcga
    68341 gtattggtaa aactgaaacc gtagattatg aaaaaatgat ctgttgagca ttaattaatc
    68401 tgaagataag aagtcgataa aaaggagata cgatgcccaa actatcaaag cgagttttag
    68461 aaatgaaaga gagtgttact ctggctgcag gtgctagagc taaggctttg aaagcgcagg
    68521 gccgcgatgt actgaattta actttaggag aaccagattt ttttacacct aagcacattc
    68581 aagacaaggc gattgaatct attcaaaatg gtacggctag cttttataca aatgcttctg
    68641 ggcttccaga attaaaagct gcgattgcca catacctgaa aaatcagtat gggtatcact
    68701 tgtctcctga tcagattgtg gcaggaacag gtgccaagtt catcctttat gcctttttta
    68761 tggctgtttt aaatcctggt gaccaagttc tcattccaac accatattgg gtatcttatt
    68821 ctgaccaagt aaaaatggca gaaggtcagc cgatcttcgt tcaaggacta gaagaaaatc
    68881 aattcaaggt aactgttgac cagctggaaa gagcaaggac aagtaagact aaagttgtcc
    68941 ttatcaattc tccttccaat ccaacaggca tgatttatgg tgctgaggaa ttaagggcca
    69001 ttggagaatg ggcggtgcac aacgatattc ttattctggc agatgatatt tacgggtcct
    69061 tagtctataa cggcaatcag tttgttccta tttcaacact ctcagaagcg attcggcgtc
    69121 aaaccattac ggtcaatggc gtggctaaaa gttatgccat gacaggctgg cgggttggtt
    69181 ttgcagcagg tgaaccagag atcatttcgg caatgagtaa gatcatcggg cagactacct
    69241 ctaacctgac aaccgtttca caatatgctg ctatcgaggc tttctgtggt agtcagtcat
    69301 cacttgaaga gatgcgatta gcatttgaag agcgccttaa tatcacttat ccattgttgt
    69361 gtcaggtccc tgggtttgag gttgttaaac cacaaggagc tttttacttc tttccaaacg
    69421 ttaagaaagc catggaaatg acaggttttt ccgatgtgac aagctttgct aatgctattt
    69481 tagaggaagt cggattagct gttgtgagtg gagcaggctt tggcgcaccg gaaaatgttc
    69541 gtctgagtta tgctacagat atcgaaaccc ttaaagaagc tgttcgtaga ctgcatgtct
    69601 ttatggaaag taatgaaatt aattaaataa aaatagagag aaacttatgt caaaaaaact
    69661 tatttcaatt gttgatgtta aagattatgt tggtcaagaa gttactattg gtgcttgggt
    69721 tgctaacaaa tcaggtaaag gtaagattgc gtttgtacag ttacgcgatg gttctgcttt
    69781 tttccaaggt gtcgctttta aaccaaactt cattgaaaaa tatggtgaag aatcaggtct
    69841 tgaaaaattt gacgttatta aacgtctcaa ccaagaaaca tctgtttatg taacagggat
    69901 tgttaaagag gatgagcgtt ctaaatttgg ctatgaactt gatattactg accttgaaat
    69961 cattggagag tcacatgaat atcctataac tcctaaagag catgggacag acttcttgat
    70021 ggacaaccgt catctttggt tgcgttctcg taaacaaatg gctgttatgc aaattcgtaa
    70081 cgctattatt tatgcaactt atgaattctt tgaccaaaat ggttttatca aatttgatag
    70141 cccaatttta tcagaaaatg cagcagaaga ttcaacagag ttattcgaaa cagactattt
    70201 tgggaaacca gcatttctta gccaatctgg tcaattatac cttgaagctg gagcaatggc
    70261 tctaggccga gttttcgact ttggtccagt ctttcgtgct gaaaaatcta aaacacgtcg
    70321 ccatttaaca gaattttgga tgatggatgc tgagtattct ttcttatcac atgaggaatc
    70381 acttgacctt caagaagctt atgttaaagc attgatccaa ggcgttctag atcgtgcgcc
    70441 tcaagcactt gatattttag aacgtgatgt tgaggctctc aaacgttata tcacagagcc
    70501 attcaagcgt gtttcttatg atgatgctat tacacttctt caagagcatg aagcagatga
    70561 agatacagat tatgaacatt tagagcatgg tgatgacttt ggttccccac atgaaacttg
    70621 gatttctaat tactttggag taccgacatt tgtggtgaat tacccagcaa gctttaaagc
    70681 attttatatg aaaccagttc ctggaaatcc agaacgcgtt ctttgtgctg atcttttagc
    70741 tccagaaggt tatggagaga tcattggcgg ctcaatgcgt gaagacaact acgatgctct
    70801 tgtggctaaa atggatgaac taggtatgga taaatcagaa tatgactttt accttgacct
    70861 tcgtaaatat ggctctgttc ctcatggcgg ttttggtata ggtattgaac gtatggtaac
    70921 ttttgttgct ggtaccaaac atattcgcga agctattcca ttcccacgta tgttacatcg
    70981 gattagaccc taataataca aaaagttcat gtcatctatg aactttttgt attggtaaga
    71041 agtgagtgtg ttataaaaac atcaatatgt cctaaaggag agataagaaa tagtagagtt
    71101 tgaacctaca tcctttgtga agataaattt tggaagttta gtagatcagt tagcagataa
    71161 gacaatatag ctttgctcaa gggatatttt atagacaagt atttggacta cgattatcaa
    71221 atagacactc tcatttgata ctaaaaaggt ctcgtctatt catataatag gagagctacg
    71281 ggagttatta ttaaaattag ctgattttta cagttcaaaa tgtgttacca ctttttcact
    71341 tcttagcttt cttatgtatg tggtataatg aaggtggacg gttcgataga gaaagggaaa
    71401 ttgtaaatgt cagacaaaca cattaattta gttattgtga caggaatgag cggcgctgga
    71461 aaaacagttg ccattcagtc ttttgaggat ctaggctact ttaccattga taatatgccc
    71521 ccagccttgg ttccaaaatt tttagaatta attgaacaaa ccaatgaaaa tcgtagggtg
    71581 gctttggttg tcgatatgag aagtcgtttg tttttcaagg aaattaattc taccttagat
    71641 agtattgaaa gcaatcctag cattgatttt cggattcttt ttttggatgc aacggatgga
    71701 gaattggtgt cacgctataa agaaaccaga cggagccacc ctttggctgc ggacggtcgt
    71761 gtgcttgatg gtattcgatt ggaaagagaa ctcctatctc ctttgaaaag catgagccaa
    71821 catgtggtgg atacaacaaa attgacccct agacaattgc gtaaaaccat ttcagaccag
    71881 ttttctgaag ggtctaatca agcctctttc cgtattgaag tgatgagctt tgggttcaaa
    71941 tatggtcttc ctttggatgc ggatttggtt tttgatgtgc gttttctacc caatccttat
    72001 tatcaggtag agcttcgtga aaaaacagga ctagatgagg acgtttttaa ttatgtgatg
    72061 tctcacccag aatcagaggt gttttacaag catttgttaa accttattgt ccctatctta
    72121 ccggcttacc aaaaagaagg gaagtctgtc ttgacggtgg ctattggctg cacaggaggc
    72181 caacaccgca gcgttgcctt tgcccattgc ttggcagaaa gtctggcaac agattggtcg
    72241 gttaatgaaa gccatcgtga tcaaaatcgt cgtaaggaaa cggtgaatcg ttcatgaaaa
    72301 atcctaaaat gactgttata ggtgggggta ctggcatctc cattatccta aaaagccttc
    72361 gtaatgaagc agttgatatt actgctgtgg tcactgttgc agatgatggt ggttcctcag
    72421 gagaacttcg taatgccatg caattagctc cgccaggaga cttacggaat gtcttgttag
    72481 cgatgagtga catgccaaaa ttttatgagc gggttttcca ataccgtttt aacgagagtg
    72541 atggagcctt ggctggtcac cctctaggca atctcattat tgctggtatc tctgaaatgc
    72601 aaggctcaac ctacaatgcc attcaaattt taaccaaatt tttccatatt acaggtaaaa
    72661 tttacccctc tagcgagcag gccttgaccc ttcatgctgt ttttaaagat gggcatgaag
    72721 tagcaggaga aagttctatt gccaaatacc caggcatgat tgaccatgtc tatgtgacca
    72781 acacctacaa cgaccaaaag cctcaggcca gtcgtaaggt ggttgaggct attctagaaa
    72841 gtgacatgat tgtcttggga ccaggctcac tgtttacctc tattttacct aatttggtca
    72901 ttccagaaat taaagaagct ttgcgccaga ctaaagcaga agtggtgtat atttgtaata
    72961 tcatgaccca gtatggtgaa acagaacaat tttcagatgc agaccatgtg gctgttttaa
    73021 atcagcactt aggaagagat ttgattgata cggttttggt aaatgtggct aaggtgccgc
    73081 aggcttacat gaattctaac aaatttgatg aatacctcgt tcaggttgat cacgactttg
    73141 ctggcctttg cagggctgct aagcgtgtga tttcgtctta ttttttacgg ttggagaatg
    73201 gcggagcttt tcacgatggt aacttagtgg tggaagaatt aatgaattta gtgaggatag
    73261 tcaagcaatg agttttacaa ccaaggtcaa agaggaatta attcacttgt ccacaggtga
    73321 caacaatgaa ttggccgcca ttatcaaatt atcaggcagc ttgggcttag ctcaccaaag
    73381 ccttcattta tccattacca ctgaaaatgc taaaattgcc cgctacattt attctcttat
    73441 tgaagacgcc tatgttatcg tgccagaaat caggtatcat caaaagacga acctgcgcaa
    73501 aaaccgtgtt tacaccgtct atgttgagca aggtgtggaa accattttag ccgatttgaa
    73561 attagcggac tccttttttg gtctggaaac aggcatcgaa cctcaggttt tatcagacga
    73621 taatgctggc cgttcttatc ttaaaggggc ttttctagcg gcaggtagca tcagagatcc
    73681 tgagtcaggc aagtatcagt tagaaatcta ttcagtttat cttgatcatg ctcaagattt
    73741 agctcaactc atgcaaaaat ttatgctaga tgccaaaacc atcgagcata aaagcggtgc
    73801 agttacttat ttgcaaaagg cagaagatat catggacttt ttaattataa ttggtgccat
    73861 gtcctgcaaa gaagactttg aagccatcaa attacttcga gaagctcgaa atgatattaa
    73921 ccgtgccaat aatgcagaaa cagctaatat tgccaaaact atcagtgcta gcatgaaaac
    73981 cattaataat attattaaaa tcatggacac aattggttta gaaagtttac cgattgaatt
    74041 gcaacaggta gcccagcttc gggttaagca tccagactat tccattcaac aagttgctga
    74101 tgctcttgag ttcccaatca ccaagagcgg ggtcaaccat cgcttgcgta aaatcaataa
    74161 aattgcagat gacttataga acatttttat cgtatgagcc tttgttcata cgattttttt
    74221 gtctaaaagt cgttttccat tgtttttttg aagtgtctga tgttctgtga tatgataaaa
    74281 gggataataa cgtttgtaaa ggagactgat aatggcatgt acaactatac tcgtcggtaa
    74341 aaaggcatct tatgatggct caaccatggt tgctcgaaca gaagattctc aaaatggtga
    74401 tttcacgcct aaaaaaatga ttgtggtgaa accagaagat caaccgagac attaccgttc
    74461 ggtgcaatct tcctttgaaa tggacttacc ggacaatccc atgacttaca cgtctgttcc
    74521 cgatgcgctt ggtaaagatg gtatctgggc agaagcaggc gtgaacgagg ctaatgtggc
    74581 catgtcagca actgaaacca tcactaccaa ttctcgtgtt ttaggggcag atcctctagt
    74641 agcttctggt attggtgagg aggacatggt gaccttagtg ctcccttata tccgttctgc
    74701 gcgtgaaggg gttttgcgcc ttggtgccat tttagaagac tatggcactt acgagtcaaa
    74761 tggtgtggct ttttcagatg aacatgacat ttggtggctg gaaacgattg gtggtcatca
    74821 ctggattgca agacgggtgc cagatgatgc ttatgtcacc aatcccaatc aatttggcat
    74881 tgatcatttt gaatttaaca atcctgaaga ttacctttgc tcagctgatt taaaggactt
    74941 tattgacacg tatcacttag atttaaccta tagccatgag cattttaatc cgcgctatgc
    75001 ctttggtagt caacgtgaca aagaccgtca gtataatacg ccacgtgctt ggatcatgca
    75061 aaaattctta aacccagaaa ttgtgcaaga cccgcgcagc tttgcccttg cttggtgtca
    75121 aaaaccttac cgtaaaataa cagtagaaga tgtcaaatat gtattgagta gtcactatca
    75181 ggacacgggt tatgaccctt acggttcaga aggaactcct gttagtaaga aagtctttcg
    75241 ccctattggc attaaccgta ccagccaaac cgctatctta cacattcgtc ctaataaacc
    75301 tcaagaaatt gccgctattc aatggatggc ttatgggtca atgccattta ataccatggt
    75361 gccttttttc acacaggtga agactattcc agattatttt gccaacactt acgaaaatgt
    75421 gtttaccgac aatttctatt ggaccaaccg tctgattgcg gctttggcag atcctcacta
    75481 caatcatcat gaaactgatt tggacaatta cttggaagaa accatggcaa aaggtcatgc
    75541 catgttacat gctgtggaag cacagttatt ggctggtgaa acagtcgatt tggaagagga
    75601 aaatcaaaaa atgagtgact atgtgcaagg agaaacgcag acgctgttga acaagattct
    75661 ctttgacgct agcaatctaa tgaccaatcg tttcagtttg agcgattaat agtgaagcta
    75721 aggctgagca actgcttagc cttttttacg ataacttttt aggaaaagta atcgcaaaaa
    75781 gacaaaaact tggaaaaaaa atcaaagtat gctatactta actggtcaat ttttaaccag
    75841 ttaataacaa aggaggaatc atgaaaaaga aaattctttt aatgatgagt ttaatcagtg
    75901 tcttttttgc ttggcaactt actcaggcaa aacaagtctt agcagagggt aaagtgaagg
    75961 tggtgacaac tttctatcct gtttatgaat ttacaaaagg ggttattggt aatgatggcg
    76021 atgttttcat gcttatgaaa gcaggaacgg aacctcatga ttttgagcct tctacaaaag
    76081 acattaaaaa aatccaagat gcagatgcat ttgtttatat ggatgacaat atggaaactt
    76141 gggtttctga tgtgaaaaaa tcattgacat ctaaaaaagt gaccatcgtc aagggaactg
    76201 gtaacatgct cttggtagca ggagctggac atgaccatca ccatgaggat gctgacaaaa
    76261 agcatgagca taataaacat agcgaagaag gacacaacca tgcttttgac ccacacgtgt
    76321 ggttgtcacc ataccgtagc attacagtcg ttgaaaatat tcgcgacagt ctttcaaaag
    76381 cttacccaga aaaagcagag aacttcaaag ccaatgccgc tacttatatt gaaaaattaa
    76441 aagagcttga caaagactat acggcagcac tttcagatgc taagcaaaag agctttgtga
    76501 cacaacacgc agcttttggt tatatggcac ttgactatgg cttgaaccaa atttctatta
    76561 atggtgtcac accagatgca gaaccatcag caaaacgtat tgctactttg tcaaaatacg
    76621 ttaaaaaata tggcatcaaa tacatttatt ttgaggaaaa tgcgtcaagt aaagtcgcaa
    76681 aaaccctagc taaagaagca ggagttaaag cggctgtgct tagtccgctt gaaggtttga
    76741 ctgaaaaaga gatgaaagct ggccaagatt actttacggt catgcgtaaa aaccttgaaa
    76801 ccttacgctt aaccactgat gtggctggta aagaaattct tccagaaaaa gacacgacta
    76861 agacagttta caatggttat ttcaaagaca aagaagtcaa agatcgtcaa ttatctgact
    76921 ggtcaggtag ctggcaatct gtttacccct atctacaaaa tggtacttta gaccaagttt
    76981 gggactacaa ggctaaaaaa tctaaaggta aaatgacagc agccgagtac aaagattact
    77041 acactactgg ttataaaact gacgtggaac aaatcaaaat caatggtaag aaaaagacca
    77101 tgacctttgt tcgtaatggt gaaaagaaaa ccttcactta cacatacgcc ggcaaagaaa
    77161 tcttgaccta tccaaaagga aatcgcgggg ttcgtttcat gtttgaagct aaagaagcag
    77221 atgctggcga attcaaatac gttcaattca gtgaccatgc cattgctcct gaaaaagcaa
    77281 agcatttcca cctgtactgg ggtggtgaca gccaagaaaa attacataaa gagttagaac
    77341 attggccaac ttactacggt tcagacttat ctggtcgtga aatcgcccaa gaaatcaatg
    77401 ctcattaatc ttaactcact aagcaaatct tcttttaagg aggtttgctt tttctttgtg
    77461 gagtaaaaaa atttaataat tctcaacatt aatttgacgg acacttatga ttataatata
    77521 ctttaagtgg ttataacaag ttagaggtga ataagatgcc aaaagaacaa ccactctatc
    77581 tacagattgt tgatgacttg gaagtgaaaa tcaaaaaaag catgacagaa aacgataagt
    77641 tgttgtcaga acgagaatta agtgaccttt acggtgttag tcgtatcacg attagactga
    77701 ctcttaagga attggaatta cgagacttaa tttataaaaa gcagggcaag gggacttatg
    77761 tttcaggaat caaagaacct gccactgatt tatcaagtac ttacagcttt acagagcaga
    77821 tgaaaaaaat ggggaaaact cctaaaacag agattctttc ttttgaacag tatcaggtaa
    77881 caccttactt gtctggtctc ttagagcttg atcccgatac agaagttttt gaattagaac
    77941 gcctaaggat tgcagatgat atgcccttga tgtttgaacg atcctatatt cctgctcagc
    78001 cttttcaggg gttaagcatt gcggacttaa agcgtaaagc tttgtacgat atctttgcaa
    78061 aggactatca agaaacaatc cgtcttgcag aagaagagtt ttatgccagc attgccttgg
    78121 actatgaagc aggtctctta ggcattaaaa agggagatcc tgtcttacat attattcgta
    78181 aaacttataa tgataaaaat atcttaattg aattgacttt cagcattgca agggcggatc
    78241 agtttaggta ccgggtgcaa catcacccta atggttaagg aattggaggt taggacatgt
    78301 ttacaaaaac gcaggaagct ttggaggctc ttggtgcagc tatcactacc aaggaaatta
    78361 aacaagaacc ccgtttatgg caagaaacca tgacgttttt tgaagaaaca agagattctc
    78421 tggattcttt tttaaagaga gtttgtaaca gcgctaacag aaataacgtt catgtcatct
    78481 ttacaggtgc gggtacatct gagtacatcg gtaataccat ttgcccttac ttgaagaagg
    78541 tggggaatcg gcagcgctat ctctttgaga gcgttgcttc aaccgatttg gttgcggcgc
    78601 cagattatta tcttgttgag gaagagacgg tactattagt ctcctttgct aggagtggta
    78661 atagtccaga aagtgtagcg gctgttaacc tggtcaatca actagtgcca aatagttatc
    78721 atttaaccat tacctgcgcc aaagatggag aactggcgaa aaaagcacag caagatgagc
    78781 gttcttacct ttatttgatg cctgaagacg ctaatgatgc tggttttgcc atgactggta
    78841 gttttacctg tatgatgcta gcggctcttt tgatttttga tgatgctaac agtatagctc
    78901 agaaagaagc ttatgtgact gatatgattc ttgctgggca agctgttatt gaccaagaaa
    78961 gacggctaca agagctagct gatttaggat ttgaacgttt agtttatcta ggttctgctg
    79021 gtttagccaa gttaacccaa gaagctcaat taaaaatgtt agaattgaca gctggacaag
    79081 ttgcgaccct ctacgagtcc tctatgggct ttaggcatgg tccgaaatct tttattaatg
    79141 accgtacctt agtcattgga tttgtcaata atgatgctta cgtcagacag tacgatttgg
    79201 acatgttaga ggaaatccaa gcagatggca ttgcccttaa aatcttggct ctattgcaag
    79261 gaggggatat caacttttca gaggaccaat ttcgactaga cacccgtcac ttattgccag
    79321 acgcttactt agcttttccc atgattttag tcgcgcagac cttggccctc ttaacggccg
    79381 ttacattagg aaattcccct gacaccccat ctgcgacagg aacggttaat cgtgtggtca
    79441 aaggagtaac gattcaccct tacccgacta gtagtcgtca atgcaacaaa gcttaaagct
    79501 tttgtgtaga agccgtaaaa cgaaatgatt ttgtgctagt aggtcaaaag aaaaaccctc
    79561 ctgatacagg aaggtttttt gtattgtctt gcttattttg ctgcgtttgc gtctttgaga
    79621 ccgtattttt tgttgaagcg gtccacacgt ccatctgctt gagtgaactt ttgacgtcct
    79681 gtgtagaatg ggtgtgaatc tgatgaaatt tccacacgga taagtgggta agtttcacct
    79741 tcaaactcaa cagtttcttt agaagctttt gttgagccgc taaggaactg gtaacctgta
    79801 gttgtatcta ggaaaacaac tggacgataa tctggatgaa tgtcttttct catcttaaaa
    79861 aattcctttc tgccatgaca cttaatgcat catagttatt aaccattcta gtgtaacaaa
    79921 acttgaatga cttgacaagg cttttctttc cttatttttt aaaaatccta aatctcttgg
    79981 caaacagcga tgagttctcg gaaaatagct tgattttctt ctaaattagc tgagttggct
    80041 ccgctagcaa ggggatgccc ccctccaccg tgacgcttag caatgccatt aataatcttt
    80101 tctttactgc gcatacgcac acggtagttg ccgtcagtta actcaacaaa aatagcccaa
    80161 gcttgaacgt tatcaatttt accaggagca cagacaatgg cagagctttc tgctagggtc
    80221 acgtcaaaat gttttaaggt ttcttggctg acaaggacat aagcagcccc actctcatca
    80281 attgttaaat gctcaaagac gtagctttgc agctttgcta ttttcaaagg aaacgaatcc
    80341 atttgccttg aaatcgcagc aaagtcgaac tcgaaatgtc tgagttggct agcaatggaa
    80401 agggttttac tagtggttga ggcataaaga aatcgccctg tatcaccaac gataccggtg
    80461 tataagagct tagcagcctt gtcagagaga gtaagattct gactaaaggc aaagtctgca
    80521 atgatttcac ttgcgctaga agcgcttgtg tccacataat agaagtcacc atacacatca
    80581 tcgttgggat ggtgatcaat cttaattaag cacttcccca gtgtgtagcg ctcatcatca
    80641 atccttggtc gattcgctgt atctgtaatg atgaccaaag cctctttata gtctttgtca
    80701 gtcacctgat ccatttggct aatccaagct aaactaggct catcaaaacc agtcatcaaa
    80761 acctttttgt ctgggaaatt ttgtgcaata atttctttca agccggcctg actaccaaga
    80821 gcatcagggt caggattttg atggcgatgg ataataatag tttggtgagc ttttatttta
    80881 tctaaaattg tttcaaaagt tgttatcatg ctttaatctt tctttttcaa aaagaggaaa
    80941 ataaccgttt aacatagtct tcaaaaaacg gtttgtgtca tagggaggtg tgcgttatgt
    81001 taagtggcta atgctagaat tttttaagat tgtcaaagac cataaattga cattttatct
    81061 gaaaatcata tcctatttta ttatagcata aaagtaagct ctagataatg gtaaattaat
    81121 ctaggaagaa aagaggttag ttatcagtta tgatactatc aaagctagtc ttgcaaatgc
    81181 aagtgaaaaa atagttttta agtgttttaa gcaatcatat caaccttctc gttaaacaat
    81241 tagtgctttt cctaaaaaag tgtgctaaaa taaacatagt ttagtaattt tgggaggaat
    81301 ttatggcatt agcaaaaatc gtttatgcca gcatgacggg aaatactgaa gaaatcgctg
    81361 atatcgttgc aaataaattg caagaattgg gccatgatgt tgacattgat gagtgcacaa
    81421 cagttgacgc ttcagagttt gagaatgctg atatcgctgt cgttgcgact tatacttatg
    81481 gtgatggtga cttaccagat gaaatcgttg atttttacga agatttacaa gatttagatt
    81541 tagaaggtaa aatctatggc gttgtcggct ctggtgacac tttttatgac tatttttgca
    81601 aatctgttga tgacttttca gagcaatttg cgcttactgg tgccatcaaa ggtgcagagc
    81661 ctgtcaaagt agacttggca gcagaagatg aagacatcga tcgtttagag gcctttgcag
    81721 agcaactctc acaggctgtt aataatctat aaaactattt agtaaaaatg tcagggactt
    81781 ccttggcatt tttagatttt taacctaaaa taaagggaat gtcacttcag ggtaggaatt
    81841 gaaaaaaaca atcagcttca ccttgcttct gatcctctta ttaactataa taaaaagata
    81901 atctaataca tctagaaaag gaaagttatg cgtttagaaa agatacgaca agaaatcaat
    81961 ggtattgatc accacttggt tgccttatta gaaaagcgga tggcacttgt agagcaagta
    82021 acagcttata aactagccaa tcacttgcct gtcttagatc aggcgaggga aaatcagatc
    82081 ctagataggg tttcttatct cgttaaagac caagcatttg agccagctat ccatgagacg
    82141 tttaaaacca ttatgtctct ttcacggcag tatcaaacgc aacacttaac aggtggtgac
    82201 attaatgatt aaatcaattg caacactgcc taaaccttcc ttgaaagaag tgttaggact
    82261 agtaggatta gcacttccca tagggggcgc ggttggagtg gttgatgtta tttttggcaa
    82321 agggcttttg tttctttccg aatatcgcga tcaccacctt ttcttgcttc ttccatttct
    82381 tgccctagca ggccttgtta tcgtttttct ttacgataag ttaggcaaag aggttcgtca
    82441 agggatggga ttggtttttc aggtagggca tggtcaaaaa aatcagattc ctcctattct
    82501 cattcctctt attttgttct caacttgggt aacccactta tttggagcga gtgcgggtag
    82561 agaaggggta gccgttcaaa taggagctac tatctctcat tattgtcgga gatttgtgac
    82621 tagtcaagaa gccgcacgac atcttttgat tatggggatg gcagccggtt ttgcagggct
    82681 ttttcaaacg ccaattgctg ctgtcgtatt tgccctcgag gttttattag taggaacgct
    82741 tcgttattcc gctttattgc cttccttagt tgctgcttac gtggcttctt ggacttccca
    82801 tgccttggga ttagagaaat ttacgattgt tcttgaagaa acattgacca taactccctt
    82861 aacattggtt aaattaattg ggttaggcct tatttttggt ctggtgggaa atagttttgc
    82921 ctatttactt ggctggttta aaccttacct cagtcaaaag ctaccaaatc cttatttccg
    82981 gattgctttt atcggtgctt tgttatctat ctgtctgatg attggtcacg tcggaagata
    83041 tagtggtcta ggaaccaatt tgattgcggc agctttttct ggccaaacta tcctaactta
    83101 cgactggctt ttaaaaatga tcgtgacggt gattagctta tctgcaggct ttcaaggtgg
    83161 tgaagtgacg cctctatttg ctattggagc ttctttaggc atcgttttgg ccccttactt
    83221 aggtcttcct gtactgttgg ttgctgcact tggttacacc acggtatttg gaagtgcaac
    83281 aaataccttt tgggccccta tctttattgg gatagaggtc tttggtccag agaatgccct
    83341 agcatatttt gtcacctcgg ctgcagccta tatggttagt cacagacatt ccatttacag
    83401 ttatcaaaaa gtagtcatga tcaatttaaa agacatgacg gtaaatcaga tggatttaaa
    83461 aaaatagctt tacaataaag aagctttttg ttagaataaa tctcgtgtgt aatggacaca
    83521 cgaaaattac ggctaatccg ctaagacaag tacttaagat tagtaagata ggagaataaa
    83581 aatgaatcca ttaatccaaa gtttgacaga aggtcaactt cgctctgata tccctaactt
    83641 ccgtcctggt gacactgttc gcgttcacgc aaaagttgtc gaaggaactc gcgaacgtat
    83701 ccagatcttt gaaggtgttg ttatttcacg taaaggtcaa gggatctcag aaatgtacac
    83761 tgttcgtaaa atctcaggtg gtatcggggt agagcgtaca ttcccaatcc acacaccacg
    83821 tgttgacaaa atcgaagtta tccgccacgg taaagtccgt cgtgcgaaac tttactactt
    83881 gcgtgcatta caaggtaaag cagctcgtat caaagaaatt cgtcgttagt ttgaaccgaa
    83941 acgtaacgta atagaataaa aagactagag tctctagtct ttttatgtcg tcgtgacaat
    84001 gtgacaattg gtgattaacg ctatgcttgt aggacacttt gaaagttcct tagcagttat
    84061 aattagtata ttgtaataac aaaatgaagc aaaataaact ttcagttatc tgatatttca
    84121 tcttgcatta ccttattttc taggttaaaa tagaagacaa ggtgagtata agatagaccc
    84181 cttagttcaa tggatataac aactccctcc taaggagtag ttgctggttc gattccggca
    84241 ggggtcatta ttgtcactga aaaagccttt acatcaaagg ctttttgttt tattccggtt
    84301 ttaaaagggt cagtttgttt atttataatt tctttcatgt ttacagttgt gtgactgtaa
    84361 atagataatg ttgtttttgg atcgctgtga ccaactctat ccattatcgc atttagcggt
    84421 atcccttttt ctgctaaaaa tgatatatgc gagtgtctaa ataagtgcgt gtgataatct
    84481 ccgtaaattt tcaatcgctt attgatgtac gcgtttaaaa ttggtaaacc ttttgaatat
    84541 ggaaagctgt tagcactctg cttgtgatta atctatcgta tgttaaaagt gacatttaaa
    84601 ttaaatcatt ttttatacat atatttcaaa aggatttatc atattggaaa atagcggtgc
    84661 ttctattggc attttactat tgacaggaat ttccctgcct tttgtctcct aaagaagatc
    84721 agctttgatt tctaacttga ttagagtggg cttggtactg tttatgaatt atcagtacat
    84781 actttctgga gatcaaaaag gaaaggaaca gctaaagagg tgtatgtgtt accattagag
    84841 gaatagaaca tcgcaagact cgtttattca gtcattacga tacctgtttt atttgtgaaa
    84901 taactataat attaagtgaa tttgtgatat aatgaaaggt atgaattatc aagattatat
    84961 atgggatttg ggaggtacct tactcgataa ttacgagctt tcaacccaag cttttgtcca
    85021 aacgctagct tttttcagcc ttccaggaga tcacgatgct gtttaccaaa aattaaaaga
    85081 atcaaccgct atcgctgtgg caatgtttgc tcctaatgag ccagaatttt tgcatgtgta
    85141 taggctaaga gaagcagaca aattggcaca acccatttgg tgtttgggag ctaaagaaat
    85201 tttgggaaag atagcgactt caggttcgcg aaatttttta atttctcatc gagattgtca
    85261 ggtgaaccaa cttttagagc aagctgggtt gctaatctat tttacagaag tcgtgacagc
    85321 ttcaaatggc tttgctcgga aaccaaatcc tgaaagtttg ttttatttaa aagaaaagta
    85381 tgatattaat agtggattag taattggaga tcggctaatt gataaacaag caggacaagc
    85441 agcgggtttt aataccttgc ttgttgacgg tagaaaaaac ctattggaga tagtaacgta
    85501 gatgattgaa gaaaataaac attttgaaaa aaaaatgcaa gaatacgatg ccagtcaaat
    85561 tcaggttcta gaagggctgg aggctgtccg catgcgtcca gggatgtata ttggctcgac
    85621 agctaaagag ggtttgcatc atttagtctg ggaaattgtt gacaactcaa ttgacgaagc
    85681 attagcaggt tttgcctctc atattaaagt ctttattgaa gcagataatt ccattacagt
    85741 agtagatgat ggccgtggaa ttccagttga tatccaagcc aagacaggac gtcccgccgt
    85801 tgaaacagtt tttacagtct tacacgcagg tggtaaattt ggtggaggcg gctataaggt
    85861 ttctggagga ttacatggtg tagggtcatc tgttgttaat gctttatcaa cacaattaga
    85921 tgtacgtgtt tataaaaacg gccaaattca ttaccaagaa tttaaacgcg gggctgttgt
    85981 agcagatctt gaggtcattg gaaccactga tgtgactggc acgaccgtac actttacacc
    86041 cgatccagaa atttttaccg aaacgactca gtttgattac agtgttttag caaaacgtat
    86101 tcaagagtta gcctttttga atcgtggttt aaaaatttcc attacagata agcgctcagg
    86161 tatggaacaa gaagaacatt tcctttatga aggtggaatt ggttcttatg ttgaattttt
    86221 aaatgataaa aaagatgtta tctttgaaac gcccatctat acagatggtg aattagaagg
    86281 tattgcagtt gaagtagcca tgcaatacac gactagctat caagaaacag tcatgagttt
    86341 tgctaataat attcatactc atgaaggtgg aacgcatgaa caaggcttta gagcggctct
    86401 tactcgggtc atcaatgact acgctaagaa aaataaaatt cttaaagaaa atgaggacaa
    86461 tttgacagga gaagatgttc gtgaaggttt gacggcggta atttctgtta agcatccaaa
    86521 tcctcaattt gaaggtcaaa ccaaaacaaa attgggcaac tcagaagtgg ttaagatcac
    86581 taatcgtctc tttagtgagg cctttcaacg ttttcttttg gaaaacccac aagttgctcg
    86641 taagattgtg gaaaaaggga ttttggcttc taaagctaga attgcagcta agcgagcccg
    86701 cgaagtcacc cgcaaaaaat caggcttaga aatttcaaac ttacctggaa aattagcaga
    86761 ctgttcgtca aatgacgcta accaaaacga acttttcatc gtcgaaggag attcagcggg
    86821 tgggtcggcc aaatcaggtc gtaaccgaga gtttcaagct atcttgccta ttcgcggtaa
    86881 aattttgaac gtggaaaaag caactatgga taagattctt gccaacgaag aaattagaag
    86941 tctctttacc gctatgggta caggttttgg tgcagatttt gacgtgtcaa aagctcgcta
    87001 ccaaaagctg gttatcatga ccgatgccga tgtggatggc gctcatatta gaaccttact
    87061 tttaaccttg atttaccgct ttatgagacc tgttctagaa gctggctatg tttacatcgc
    87121 ccagccacct atttatggtg ttaaggtcgg tagtgagatt aaagagtata ttcagccagg
    87181 tattgatcaa gaagaccaat taaaaacagc tcttgaaaaa tatagtattg gtcgttcaaa
    87241 accaactgtt caacgttata aaggtcttgg ggaaatggat gaccatcaac tttgggaaac
    87301 tactatggat cctgaaaatc gtttgatggc gcgtgtgaca gttgatgatg ccgcagaagc
    87361 agataaagta tttgatatgt taatgggaga tcgtgttgaa ccaagacgtg atttcattga
    87421 ggaaaatgcg gtttatagta cactggatat ttagtcacct ttttagtttc acaaggaatc
    87481 tgctaccaaa gaggacgaat tgactaaaaa tcatgatgca tgatgccaac agctttgtta
    87541 gttagtacgt cttcatcttg agggacagcg ttaatgcata ggtattgaga ccgcccctta
    87601 atacctatgt tagtccttat taagaaagcc ttttgagtcg ctggtacgag attgttgaat
    87661 tagtcaaata tattttgaaa tgcattttaa agtatgttat aatcgtaatg ttatagtgta
    87721 ttttaaataa aattttaata aaaggcgatt gaggaatttc agtttttagt tattactgga
    87781 acaatgttga taaatcgtgt ctaaataata aggagattca gatgtcaagc ggaattatct
    87841 tgctgattgt ggctatagtc ctactagtga ttatcgccta tctagtgggt gtcatcatac
    87901 gaaagcgtaa tgattcccta attaccagtc tagaagaacg aaaacaggcc ttgtttgctt
    87961 tgcctgttaa tgatgaaatt gaagaagtaa agtcacttca tttgatagga cagagccaaa
    88021 cctcttttcg ggaatggaat cagaaatggg tagacttaac tgtgaattcg tttgcagata
    88081 ttgaaaatca tatttttgaa gctgaaaatt tgaatgatac gtttaatttt attcgcgcca
    88141 agcatgagat taatagcgtt gaaagtcagc ttaatcttgt tgaagaagat atcgcttcta
    88201 ttcgtgaagc acttaatatc ttaaaagagc aagaagaaaa aaatagtgct cgtgtcaccc
    88261 atgctcttga tttatatgaa aagctccaag cttctatttc tgagaatgaa gataattttg
    88321 gttcaactat gcctgaaatt gacaaacaga tgaaaaacat tgaaactgaa ttttcacagt
    88381 ttgtcgcact caactcatca ggtgatcctg tagaagcttc tgaagttctg gatagagcag
    88441 aagagcatac tattgctcta gggcagatta cagagcagat tccagctatt gtggccaagt
    88501 tggaagatga ttttccagat cagttagatg atttggaaac aggatatcgc cgtttacttg
    88561 aagaaaacta tcattttcca gaaaaaaaca ttgaggcacg ttttcaggag attcgtgagt
    88621 ctattcgtgc caattcatca gagttagtta cacttgactt ggatcgtgct agagaagaaa
    88681 acacgcatat tcaagaacgc attgattctc tttatgaagt ctttgagcgc gaaattgccg
    88741 cttataaggt agctgctaaa aatagtaaga tgctacctcg ttacctagaa catgtgaaac
    88801 gtaataatga acaactcaaa gatgaaattg cacgtttatc acgtaaatat attctaagtg
    88861 aaacggaaag tctgactgtt aaggcatttg agaaggatat taaagagata gaagacagta
    88921 cacttgctgt tgcagaacaa tttggtttac aagaaaaacc attttcagaa ctgcaagtga
    88981 cttttgaacg cagtataaag acgcttacta atgtcgagtc aggtcaaatg gatgtttttg
    89041 cagcagttaa agatattgaa aaaattgaat cacaggcacg ccataacctt gatgtttatg
    89101 ttactcagct tcatatgatt aaacgttata tggaaaaacg tcacttgcct ggaattccac
    89161 aagactttct tagtgctttc tttacaacga gttcacaatt ggaagctttg atggatgagc
    89221 ttagtagagg acggatcaat attgaggcag tgtcacgttt gtcggaagtt gcgacggttg
    89281 ctattgctaa tctagaagat ttaacctatc aagtggttca aaatgctacc ttgactgaac
    89341 aattactaca atattctaat cgctatcgtt cttttgaagc aggagttcaa agtagttttg
    89401 aacatgcttt gagacttttc gaagtagaaa atgattatca ggcttctttt gatgaaattt
    89461 cttatgctct tgaaacagtt gaacctgggg taacagatcg gtttgttaac tcttatgaaa
    89521 aaacacgaga gcacattcgt ttttgatact tgaaagtcgt gatattctca cgacttttta
    89581 ttagcttttt ggaccaatac gtgtttttga ctagaatctt ctttttaatg atcaaacgaa
    89641 gaagtagtaa cagtgttttt tgctattgag aggatagtta ttttttcaaa aatcttttcc
    89701 aaaaggattt ggttttttca ggagtttgtt tgctaagttg atcgtttttt gtctgcttta
    89761 agatgacttc taaacgtgtt tccttcagat ttattgcgtg gtcggtatga aggataaacg
    89821 caaaaggtga agtcatatgc gtttctgtaa taatagtaac aggtaaatgg ttttcttttg
    89881 ctaatttcat atagagtatt tgaagttgag gtgccagctt ggaagagatt tttaagtgta
    89941 aaggttgata gactaactga aggctcggta attctctttt caaatagtct tttactgttt
    90001 tagtttgagc ttcgtctaat aaagcactta aaacgactcg ttcagcatac gttcctagat
    90061 agtagcgttg ctgctcagga tttaatcttc tttctcccca ggctcctttt aatagcttat
    90121 cttctaaatt agtcatagat accctcgctt ctttataata gtttctttat tatatcgatt
    90181 tctacaataa aataccaatt tgaaaatttt cggtaaatgt gttaaaaaac aagaaagaaa
    90241 gtgatttttc ttgcaaaaaa caaaggaagc ttttcatgag attgcttttt aagttgatta
    90301 aaggcctagt ttgtggtatt atgaacatgt aaaatattaa aactcataag gagagtatta
    90361 caatgtcaat tattactgat gtatacgctc gcgaagtcct tgactcacgc ggtaacccaa
    90421 cacttgaagt agaagtttat acagaatcag gtgcattcgg acgtggtatg gttccttcag
    90481 gagcttcaac tggtgaacat gaagccgttg aacttcgtga tggtgacaaa tctcgttacc
    90541 ttggtctagg tactcaaaaa gcagttgata acgttaataa cattatcgct gaggcaatca
    90601 tcggttacga tgttcgcgat caacaagcta tcgaccgtgc aatgatcgct cttgacggta
    90661 ctcctaacaa aggcaaactt ggtgctaatg ctattcttgg tgtttctatc gctgttgctc
    90721 gtgcagctgc tgactatctt gaagtgccac tttacactta ccttggcgga ttcaacacta
    90781 aagttcttcc aactcctatg atgaacatca tcaacggtgg atcacactca gatgccccaa
    90841 ttgcattcca agagttcatg atcatgccag ttggtgcacc tactttcaaa gaaggtcttc
    90901 gttggggtgc tgaagttttc cacgctctta agaaaattct taaagaacgc ggacttgtta
    90961 cagctgtagg tgacgaaggt ggatttgctc ctaaatttga aggaactgaa gacggtgtag
    91021 aaactatcct taaagctatt gaagcagctg gttacgaagc tggtgaaaac ggcattatga
    91081 tcggttttga ctgtgcatca tcagaattct acgacaaaga acgtaaagtt tacgactata
    91141 ctaaatttga aggtgaaggc gctgctgttc gtacatctgc agaacaagtt gattaccttg
    91201 aagagttggt taacaaatac ccaattatta ctatcgaaga tggtatggat gaaaacgact
    91261 gggatggttg gaaagttctt actgaacgcc taggcaaacg tgttcaattg gttggtgacg
    91321 acttcttcgt tacaaacact gaataccttg ctcgtggtat caaagaaaat gcagctaact
    91381 caatccttat caaagttaac caaatcggta ctttgactga aacgtttgaa gctatcgaaa
    91441 tggctaaaga agctggatat actgccgttg tatcacaccg ttcaggtgaa actgaagatt
    91501 caacaatcgc tgacatcgca gttgcaacaa acgctggcca aatcaaaaca ggttcattgt
    91561 cacgtacaga ccgtattgct aaatacaacc aattacttcg tatcgaagat caacttggtg
    91621 aagttgctca atacaaaggt atcaaatcat tctataactt aaaaaaatag acggtaagac
    91681 agaaatcggt cattcgtaga atgcgatttc gtcgtcgcac ctccgtcagg ctgactaggt
    91741 tggtcacgac aaaaggagtg aacatccagt cagctacgac gcaaaagtta aagattaaag
    91801 aatagaaagc ttgggaaaat cccaagcttt ttgctttcta aatagtaaaa atttactgtg
    91861 ggctaattta tcctgagcta atgtattagc gaggtaaagt tactgaagaa gacttggatt
    91921 tgtactgcct ctaaaaagtt ggacactata ttttaaatac aggactaagt ccttttatac
    91981 caattgtcaa gcacatcaag gttttaactg aaaaaatgtt ttagacaata gcctaggttt
    92041 agctgttgtc ttacttgttg tgctctgatt agcataaaaa agtgtacaag aaaaaaacct
    92101 tgcctagtat ttttaagatc aaggtgttac aatgatagag caacaacgac tttaatgatt
    92161 ttgggtcgaa gcgtaattgt aaagtttgtt atgcgttatg aggtaaagca ttgtctgaca
    92221 aggcaatgtc tagaggcaat cgtatgtggc ttggttgaag ctgtttgcga ttgccttttt
    92281 cgtttctcat agaagtctgc gatatgacaa ggattggtat gactagcaaa agcaatgtca
    92341 tggatacact tgaaaagaat ctttggagca taaggattcc cacgtttggt aatgtgctct
    92401 tgagctagat agttgccaga ctcataatgt ctaaagtcaa tcccaatgaa agcattaatt
    92461 tgattagcag attgaaaacg acgaatagca ccgagttcgc caataatact tgttgcagtt
    92521 gtttctacga tacttggaat agagcgtaga atcttgtctt ctggtaaagg ttgagccgac
    92581 gccaccatct tatcaaaaat agcttgacga cgttcagaaa gtctaagtaa ttctttggca
    92641 tagtagcgaa cctcttctat catcggagag gttttcgtaa cagtaaaata agactgcttg
    92701 gctaatgaga caagtttttc cactaagtag atcccacgct tgtcagagat acgtttagag
    92761 gtagattgac ggatgatagc tgacaatgct ttgtcagcta gctccagtac aaagctatta
    92821 catgaaaaaa gccgttacca cattccagta ttactcacca gttggtgcaa ataagatgtg
    92881 ttccagttca ggaaaagtga cttgtaagat cttgtgaagg cgattcttaa ctctcgaaca
    92941 atattatcct cagtcaagtt ttgatagaag cgactcaagt cacgtagcag ctgataaact
    93001 tcttcctgaa cgtaagttgg ttttctaact agaataaatt gagactgagc caatttttca
    93061 gtgtctaact tatccgcttt acgcacccgt agactatcta gttttctaaa ggattgagtt
    93121 gtgtataagc gtagccattt ttctcaagga aggactgaag ccgacgagaa tagactcctg
    93181 ttgtgatggt ctcccttttg ccttttaaac aatagtatag ccgtttttca aaatgttatt
    93241 aatgattttt tcctttattc cagaagaata agtctgatac tgtttcttat taataatctc
    93301 aatgccctaa caatccatca gtcgaacggt atttctcaaa ttactgcagt tgactcttgc
    93361 gttcagttcc ctcaccttgt ggatgccgtt tagaacaata ttagcttgct gagccttttg
    93421 gtaatgtgaa caaagcatct ttatcactca aggagaagac aggttcttgt ggtaagtgtc
    93481 caacaaggtc acgataaact catcgtaccg tttttggcgg aagtctagaa atgccttatg
    93541 aatgtaagcc tcagaaacgt ctctaaaact aaacaagaaa tacaagaaca aatgcccttg
    93601 attctggtac aaatgctgta tcaggttcag gtattgccta tctgcgataa tgacactctg
    93661 cttttcctta acaatatctt tgaaaggaat gatttcgaca ttgacaggca taaccgttgc
    93721 aatagctggc gggaagtaaa ttgagagtgc attggtcatc aaatccagcg cagcagtgtt
    93781 attggtcaaa agatagacag gtatcggtgg caaatatgtt tttaggagtt cctctaactg
    93841 tatcgtgaag agcaataaat gataagacgg cagtttcccc acgatgcctt ctgcgctcat
    93901 ccattcctca acgatggttt ttagagtatt gtagaagctc ttgtttcgtt tttgctgtct
    93961 tctgaggtaa tggaacaagt gtatgtcagg taacaaaact tgaagattac tgataaatag
    94021 acgtgagaag gaaaccaaaa tccgtttgaa aggaagggag tttaggatat tattgcctag
    94081 tagtggacgc agggatgctt tcaaggtttt tccatttgtt ttgtcatcac caactcaaac
    94141 aattctttca cttttttagg tgtccattta tccttatgga aaggattatt ggtggtgcaa
    94201 aaacataaaa aaatataatc caaatcctca tcagttaact caggatggta ccattttccg
    94261 atgatttcct gactggtcat tttgatatct cgatagatag acagtttttt caagtgtttg
    94321 aatgcatctg tctgagggat ccccaagtta tcatgtcgcc gtttccatat aagggatatc
    94381 aaaatggcaa agtatgaaaa ttcataaggg gctttactgg catcattaag tgtggtggct
    94441 tgattggagt ttataatcag cgaaaccact ttattcattg atgttttatc aaaatcataa
    94501 atggtcatac caaactgata gtgcaacaag gcgatcagaa agcggatacg gtattctggt
    94561 ccaacaacat ggttttgccg aacgtttaaa cctacctttt tcaagtattt ccgacaattg
    94621 gtcctgatac ggtaagcggt ggcttgggaa atatactctc gtttaatgaa gtcgtgtagg
    94681 ctcagctctc ctggttcaat taaaaaacat aacatcttta agaatatcga ggtttgatag
    94741 agtttcttaa aataaggcat tttaagttgg taggtcttat aggggataga aacagtgtcg
    94801 tcacaaatgg ttaaggtgag ggtgtcttct aaatccttaa tcatttcaaa gagtaagttg
    94861 tagacacgtt gttttttgag ttcggtttcc tgacacaact ggtctatgga gacttcggaa
    94921 acgtctaaca aaatgttgag cagtgataat ttatcttgta atttggtttc tagatgaagg
    94981 tgtaacataa ctgaactcct ttcattttta tagcagaaac tcgtatttat ttaattatca
    95041 cataattaaa taaaacagtc aaataattca atggtgacgc gtgtttaagg agtattgaga
    95101 atgtcagata taagcaaaat gcagctgaat attcttaatt ttaggtatga aaaagcgtcg
    95161 ggattgataa aaaatctatt gaattgggta aatttaagtt gatataataa gttgattaga
    95221 aaaattaaca attcatttaa attctaatca gctgtaacgt tccggggcgt gttaaactgt
    95281 ctgaacatag aaaatacaag tttctacggt gactaagata agttaaggag gattccttaa
    95341 attctgtgat aggaacgtaa actctctaca agagtagagc acgtcatcag tcagtctggg
    95401 tgtctactgg ctgacaacgt caaataagat aggcatgaaa aaataagggg gaatacagaa
    95461 tgtttttaaa acaccaagat gtgaaacaaa aaaattggag aatgcgtaag gtcaaaaaag
    95521 tctttgttag ttcatgtatg cttttaacag tgggcctcgg agttgccgta cctactggat
    95581 tcagccaatc taatggcgtg atggttgtaa aggctgcgga agtgccggcg acagatttat
    95641 cacgtcaggc gtctgattcg gagagggtag atgaatcgtc tttattgcag aaagaaaact
    95701 tatcagtaga ttcatttaaa ttagaaaatt taaatggatg ggaagctgaa aatgatacag
    95761 caggtaattt ggggaaattt aaagatccag atagttcggg ctatcaaaat attttgacat
    95821 catctggaaa gaatatcagt gtagctgttg ctcccaaagg ttcaggtaaa atgaacatta
    95881 aagtaactaa aagatcaaat tttcagggtg gatattatgt aggtggtctt agaactcaaa
    95941 ctccggtatt gaagttaaat gatgtttatc gatattcttt tacaactaaa aaattatcag
    96001 gaaattcttc agagttcaaa acgagagtta agcccgttga atctaataat aaactaggga
    96061 aagagcttgt tattagggtg gataataaaa atgtatctac taagcatgat tggcttccag
    96121 acatctctga tggaactcat actgtggact tcactggtct tgataaaaaa ttatctgttg
    96181 ctttcagatt ttctccaaga caaacttcga atgttgttta cgaattttct aacataaata
    96241 taaaaaacat tagtcctgca tcagtgccgg ctattccttc gaaagtttta gagggaacca
    96301 gcgtcttgtc gggtactgca atatcttctg gagatacatt agaaaaaaga aaatcgtttg
    96361 atggcgatat cctaagagtt tataaagata gcaaaatcat tgctagaaca gtaataaaag
    96421 gcaataagtg ggatgttaaa ctttcaaagc ctcttattgc aggtgaaaaa ttagattttg
    96481 agattttgca tccgagatct caaaacgtta gtaaaaaaat ttcaaaacaa gtcgaagcta
    96541 aaccatttga tccagcttcc tataaagaaa aagttatagc caaattaaag ccggtttatg
    96601 aagctactag tgaaaaaatc acaaatgatg cttggttgga tgaaaatgcg aaggatttgc
    96661 aaaaacaaaa attagaagaa caatatattt ctggaaaagt agcgatatca gaggctggaa
    96721 ctaaacaaga agctatagat gcagcatata ataaatattc aagtcaaaca gatccagact
    96781 ctcttcctag tcagtataaa caaggtaata aagaaaatga acaagaaaaa gggcgtcaag
    96841 atttaatcca gactcgtgat ctgacgttga aagccattca agaagacaaa tggctaacag
    96901 agcaggagaa aacaattcaa aaagaagaag cattaaaagc ttttgaaact ggtatagaaa
    96961 gtgttaatca aacagtatca ttagaacagt tgaagcaacg gttaatagtg tataaagctt
    97021 ctgaaaaaga ttcagagaaa aaagaatatc ctgagtcaat tcctaatcag catattccag
    97081 ggaaagaaaa agaagttaaa gctgctaaac aagaagaact taaaaaatta catgacacaa
    97141 ctcttgaaaa aatcaatcaa gataaatggt tgacgccaga ccaacaagct gaacagttaa
    97201 aacaagcgga agttactttt aaaaaaggcc aagaagcaat taaaagtgct cagactttaa
    97261 ctcagcttga gacagactta gctgattatg tttctgagaa tgaaggtaag ggaaattcta
    97321 ttcccgataa atacaaatct ggccataaag atgatttggt aaataaggct gaagttaaac
    97381 ttaaggaagc tcacgaagct actaaacaag caattgaaaa agatccatgg ttgagtccgg
    97441 aacagaaaaa agctcaaaaa gaaaaagcca aagcaagact agatgagggc ttgaaagctc
    97501 ttaaagctgc agatagttta gagattctta aagtgacaga agaagctttc gttgataaag
    97561 aaaaaaatcc agattcaatt ccaaatcaac ataaagctgg aactgctgat caagctagaa
    97621 aacaagcttt agatagttta gataaggagg ttcaaaaaga gttagagtca attgataacg
    97681 ataatactct aacaactgat gagaaagcag ctgctaagaa aaaagtcaat gacgcttatg
    97741 atgtagctaa gcaaacagct atggaagcca attcttatga agatttgact actattaaag
    97801 atgagttctt atctaattta cctcataaac aaggaacgcc gcttaaagat caacaatctg
    97861 atgctattgc agaattagag aagaagcagc aagaaattga aaaagctatt gagggtgata
    97921 aaacattacc aagagacgaa aaagagaaac aaattgctga ctctaaggaa cgcttaaaat
    97981 ctgacacgca aaaagttaaa gatgctaaaa atgctgatgc tattaaaaaa gcatttgaag
    98041 aagggaaagt gaatattcct caagcacata tcccaggtga tttgaacaag gataaagaaa
    98101 aacttcttgc agaattgaag caaaaagcag atgatactga aaaagctatt gatgttgata
    98161 aaactctgac agaagatgag aaaaaagagc aaaaagtcaa aacaaaagct gaacttgaaa
    98221 aagctaaaac tgatgttaaa aatactcaga cacgtgaaga actagataaa aaagttccag
    98281 aacttaagaa agctattgaa gacactcacg ttaaaggtaa tcttgaaggt gttaagaata
    98341 aggctattga agatcttaaa aaagctcata ctgaaacagt tgctaaaata aatggtgatg
    98401 atacccttga caaagctact aaagaagctc aagtgaaaga agctgacaaa gctttggcag
    98461 caggtaaaga tgcgatcact aaagcagatg atgctgataa agtaagtaca gctgttacag
    98521 agcacacacc aaaaattaaa gcagcacata aaactggtga ccttaaaaaa gctcaagtag
    98581 atgctaacac agctcttgac aaagcagctg aaaaagaacg tggagaaatc aataaagatg
    98641 ctacactaac gacagaagat aaagcaaaac aactgaaaga agttgagaca gctcttacta
    98701 aagctaaaga taacgtgaaa gctgctaaga cagcagacgc tatcaatgac gcacgtgata
    98761 aaggcgtagc aacaattgat gccgtccata aagcaggtca agacttaggt gctcgtaagt
    98821 caggtcaagt cgctaaactt gaagaagcag ctaaagcaac gaaagacaag atttcagctg
    98881 atccaacttt gacaagcaaa gaaaaagaag agcaatctaa agctgttgac gctgaactta
    98941 agaaagcgat agaagctgtt aacgcagctg acacagctga caaggttgac gatgctcttg
    99001 gtgaaggtgt tacagacatc aagaaccaac acaagtcagg tgactctatc gacgctcgtc
    99061 gtgaggctca tggtaaggaa cttgatagag tcgctcaaga aactaaaggt gcgattgaaa
    99121 aagaccctac tttgacgact gaagaaaaag ctaaacaagt taaagacgta gatgccgcta
    99181 aagaaagagg catggctaag cttaatgaag ctaaagatgc tgatgcttta gacaaagctt
    99241 acggtgaagg tgttacagac atcaagaacc aacacaagtc aggtgaccct gtcgacgctc
    99301 gtcgtggatt acacaacaag tcaatcgacg aagtggcgca agcaactaag gacgctatca
    99361 cagcagatac gactttgact gaagctgaaa aagaaacaca acgtggcaat gttgataaag
    99421 aagcaactaa agctaaagaa gaacttgcta aggctaaaga tgctgatgct ttagacaaag
    99481 cgtacggtga cggtgtaacc agcatcaaga accaacacaa gtcaggtaaa ggtcttgacg
    99541 ttcgtaaaga tgagcacaag aaagctcttg aagctgttgc taaacgtgtc actgctgaaa
    99601 ttgaggctga tccaacctta acaccagaag tgagagaaca acaaaaagca gaggttcaaa
    99661 aagagcttga acttgcgact gataagattg ctgaagctaa agatgcagat gaagcagaca
    99721 aagcttacgg tgacggtgtc acagcgatcg aaaatgccca cgttattggt aaaggtatcg
    99781 aagctcgtaa agaccttgct aagaaagacc ttgctgaagc tgctgctaag acaaaagctc
    99841 tcattattga agacaaaacg cttactgatg atcaacgtaa agaacagtta ttaggtgttg
    99901 atacagagta tgctaaaggt atcgagaata ttgatgcagc taaggatgct gcaggtgttg
    99961 ataaagcata tagtgacggt gttcgtgaca tcctggcaca gtacaaagaa ggtcaaaacc
   100021 ttaatgatcg tcgtaatgct gccaaagaat ttcttcttaa agaagcagac aaagtgacga
   100081 aactaatcaa tgatgatcca accttgactc atgaccaaaa agttgatcaa atcaacaaag
   100141 ttgaacaagc taagttagac gcaatcaagt ctgttgatga tgctcaaaca gctgatgcta
   100201 tcaatgatgc tcttggtaag ggtattgaaa acatcaacaa ccaataccaa catggcgatg
   100261 gcgttgatgt tcgtaaagcg actgccaaag gcgatcttga aaaagaagct gctaaagtga
   100321 aagctcttat tgctaaggat ccgaccttaa ctcaagctga taaagacaaa caaacagcag
   100381 cggttgacgc agctaagaat acagcaattg cagcggttga taaagcgaca acagctgaag
   100441 gcattaacca agaacttggt aaaggcatca cagctatcaa taaagcttac cgtccaggtg
   100501 aaggtgttaa agcacgtaaa gaagccgcta aagctgatct tgaaaaagaa gctgctaaag
   100561 tgaaagctct tattactaac gacccaacct taacaaaagc tgataaagct aaacaaacag
   100621 aagctgttgc taaagccctt aaagctgcta tcgcagcggt tgataaagcg acaacagctg
   100681 aaggcattaa ccaagaactt ggtaaaggca tcacagctat caataaagct taccgtccag
   100741 gtgaaggtgt taaagcacgt aaagaagccg ctaaggctga tcttgaaaga gaagctgcta
   100801 aggttcgtga agctatcgct aacgacccaa ccttaacaaa agctgataaa gctaaacaaa
   100861 cagaagctgt tgctaaagct cttaaagctg ctatcgcagc ggttgataaa gcgacaacag
   100921 ctgaaggcat taaccaagaa cttggtaaag gcatcacagc tatcaacaaa gcttaccgtc
   100981 caggtgaagg tgttgaagca cataaagaag ctgctaaagc taatcttgaa aaagtagcta
   101041 aagaaactaa agctcttatt tcaggagacc gttacttgag cgaaactgaa aaagcagtcc
   101101 aaaaacaagc tgttgagcaa gctcttgcga aagcacttgg tcaagttgag gctgctaaga
   101161 cagttgaagc tgttaagttg gcagaaaacc ttggtactgt agctatccgt tcagcatatg
   101221 ttgctggttt agctaaagat actgatcaag caacagctgc tcttaacgaa gcgaaacaag
   101281 ctgctattga agctcttaaa caagctgcgg cagaaacact tgctaagatt acaactgatg
   101341 ctaaattgac tgaagctcaa aaagctgaac aatcagaaaa tgtatcatta gcgcttaaga
   101401 cggctattgc gactgttcgt tcagcacaat ctattgcgtc tgtgaaagaa gcaaaagata
   101461 aaggtattac tgctatccgt gcagcctatg tgcctaataa ggcagtcgca aaatcatcgt
   101521 cagcgaacca tcttccaaaa tcaggtgatg caaactcaat tgttcttgtt ggcttaggag
   101581 ttatgtctct tcttttaggt atggtgcttt atagcaagaa aaaagaaagt aaagactaag
   101641 aacctggctt tatccaaatt gctttctact atattttcaa accaaggtga ttttgaaatc
   101701 accttggttt tttggatcgt aagggcccaa gaacggagtg tattgaaaac atttcaaagt
   101761 tcaattgaaa aggcaacagt tttctgtaca gaatttataa ggcgtttttt gttcaaacga
   101821 tgactcattt agttatgggt gtttgataat taagattact gtgaaggtga tggtagttcc
   101881 accagtggac ttcctccttg gttttaaggg ttaattgttc tagtgaataa aaggtttctt
   101941 ggtcgcgcag tagggatcaa gcgagcagat aaaatgccta ttttaaatca gttcgagcga
   102001 attttcgtgc tacaagctca aaagaggcta ctaaagtatt agaatagttt atctctgagt
   102061 gaagttcttg ttataagaag atgatgttat cgtttgaaac gaccaaaaaa tctcctaact
   102121 tttactaatt tctacatgaa atctagtcca gtatttactc tacaaccttg attgattcgc
   102181 ttaataaaga catttctact tgattgttta cacatagtta ttg
//
LOCUS       DAUGJR010000002        93856 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUGJR010000002 DAUGJR010000000
VERSION     DAUGJR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 93856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93856
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.002"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(318..866)
                     /gene="raiA"
                     /locus_tag="VH800_000089"
     CDS             complement(318..866)
                     /gene="raiA"
                     /locus_tag="VH800_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEQ8361190.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
     gene            complement(946..1611)
                     /locus_tag="VH800_000090"
     CDS             complement(946..1611)
                     /locus_tag="VH800_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEQ8361191.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            complement(1583..2908)
                     /locus_tag="VH800_000091"
     CDS             complement(1583..2908)
                     /locus_tag="VH800_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8361192.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            2964..3596
                     /locus_tag="VH800_000092"
     CDS             2964..3596
                     /locus_tag="VH800_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEQ8361193.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNRQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            3724..4665
                     /gene="cysK"
                     /locus_tag="VH800_000093"
     CDS             3724..4665
                     /gene="cysK"
                     /locus_tag="VH800_000093"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEQ8361194.1"
                     /translation="MTKIYKTITELVGQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKANPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(4683..5060)
                     /locus_tag="VH800_000094"
     CDS             complement(4683..5060)
                     /locus_tag="VH800_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8361195.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(5060..6460)
                     /locus_tag="VH800_000095"
     CDS             complement(5060..6460)
                     /locus_tag="VH800_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8361196.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMCGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            complement(6497..7138)
                     /locus_tag="VH800_000096"
     CDS             complement(6497..7138)
                     /locus_tag="VH800_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8361197.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVGDRTQAVVYAFRHHLVPQDDN"
     gene            complement(7131..8135)
                     /locus_tag="VH800_000097"
     CDS             complement(7131..8135)
                     /locus_tag="VH800_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8361198.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            complement(8132..8824)
                     /locus_tag="VH800_000098"
     CDS             complement(8132..8824)
                     /locus_tag="VH800_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEQ8361199.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            complement(8947..10845)
                     /gene="pknB"
                     /locus_tag="VH800_000099"
     CDS             complement(8947..10845)
                     /gene="pknB"
                     /locus_tag="VH800_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEQ8361200.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIIFENVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSINDSTAPGSNTELSP
                     SETTSQTP"
     gene            complement(10842..11582)
                     /locus_tag="VH800_000100"
     CDS             complement(10842..11582)
                     /locus_tag="VH800_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEQ8361201.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            complement(11620..12942)
                     /gene="rsmB"
                     /locus_tag="VH800_000101"
     CDS             complement(11620..12942)
                     /gene="rsmB"
                     /locus_tag="VH800_000101"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEQ8361202.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            complement(12932..13867)
                     /locus_tag="VH800_000102"
     CDS             complement(12932..13867)
                     /locus_tag="VH800_000102"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEQ8361203.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEHEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVVVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            complement(13929..16313)
                     /locus_tag="VH800_000103"
     CDS             complement(13929..16313)
                     /locus_tag="VH800_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEQ8361204.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFIIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKSDRDFLFEGKPSVLYSTLDREKEKIALKGIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERPIDRSESYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEAKILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMSIRHQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            complement(16378..16695)
                     /locus_tag="VH800_000104"
     CDS             complement(16378..16695)
                     /locus_tag="VH800_000104"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEQ8361205.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(16711..17346)
                     /gene="gmk"
                     /locus_tag="VH800_000105"
     CDS             complement(16711..17346)
                     /gene="gmk"
                     /locus_tag="VH800_000105"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEQ8361206.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNSFKAK"
     gene            complement(17456..19063)
                     /locus_tag="VH800_000106"
     CDS             complement(17456..19063)
                     /locus_tag="VH800_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEQ8361207.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            complement(19193..20089)
                     /locus_tag="VH800_000107"
     CDS             complement(19193..20089)
                     /locus_tag="VH800_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8361208.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFTVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            20291..21478
                     /locus_tag="VH800_000108"
     CDS             20291..21478
                     /locus_tag="VH800_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8361209.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            21502..22152
                     /locus_tag="VH800_000109"
     CDS             21502..22152
                     /locus_tag="VH800_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8361210.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADVALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            22190..22813
                     /locus_tag="VH800_000110"
     CDS             22190..22813
                     /locus_tag="VH800_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8361211.1"
                     /translation="MQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSE
                     NGFVGLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQ
                     VDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQ
                     NVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN"
     gene            22846..23625
                     /locus_tag="VH800_000111"
     CDS             22846..23625
                     /locus_tag="VH800_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEQ8361212.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            23696..25027
                     /locus_tag="VH800_000112"
     CDS             23696..25027
                     /locus_tag="VH800_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEQ8361213.1"
                     /translation="MEIIGSLGVLVGVIVIIYLYVKEVNIIIAAPLATSLVILFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVAFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     VILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIVPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIVIAFDLFS"
     gene            25101..25583
                     /locus_tag="VH800_000113"
     CDS             25101..25583
                     /locus_tag="VH800_000113"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEQ8361214.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(25728..27197)
                     /locus_tag="VH800_000114"
     CDS             complement(25728..27197)
                     /locus_tag="VH800_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361215.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKLYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAVQDQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(27211..28365)
                     /locus_tag="VH800_000115"
     CDS             complement(27211..28365)
                     /locus_tag="VH800_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEQ8361216.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAAMIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKVNGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            complement(28428..28796)
                     /gene="rnpB"
                     /locus_tag="VH800_000116"
     ncRNA           complement(28428..28796)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VH800_000116"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(28810..29136)
                     /gene="gpsB"
                     /locus_tag="VH800_000117"
     CDS             complement(28810..29136)
                     /gene="gpsB"
                     /locus_tag="VH800_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEQ8361217.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            complement(29258..29773)
                     /locus_tag="VH800_000118"
     CDS             complement(29258..29773)
                     /locus_tag="VH800_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEQ8361218.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNKEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            29854..30453
                     /gene="recU"
                     /locus_tag="VH800_000119"
     CDS             29854..30453
                     /gene="recU"
                     /locus_tag="VH800_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEQ8361219.1"
                     /translation="MVNYPHNLIRQKVSSVQKQNKVDFANRGMSFEAAINATNDYYLS
                     RQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAKETR
                     QKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQIDNGS
                     KSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            30440..32605
                     /locus_tag="VH800_000120"
     CDS             30440..32605
                     /locus_tag="VH800_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8361220.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNGSHPSTDDKKTTH"
     gene            complement(33072..34409)
                     /gene="pepC"
                     /locus_tag="VH800_000121"
     CDS             complement(33072..34409)
                     /gene="pepC"
                     /locus_tag="VH800_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEQ8361221.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQY"
     gene            complement(34594..35418)
                     /gene="nadE"
                     /locus_tag="VH800_000122"
     CDS             complement(34594..35418)
                     /gene="nadE"
                     /locus_tag="VH800_000122"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEQ8361222.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKAVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREEASDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(35420..36874)
                     /locus_tag="VH800_000123"
     CDS             complement(35420..36874)
                     /locus_tag="VH800_000123"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEQ8361223.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVKEFDAIPLLVDIFVKGELVYQLPTLAEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMALIDNIRKDAYGKSE"
     gene            complement(37045..38424)
                     /locus_tag="VH800_000124"
     CDS             complement(37045..38424)
                     /locus_tag="VH800_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8361224.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(38593..39510)
                     /gene="trxB"
                     /locus_tag="VH800_000125"
     CDS             complement(38593..39510)
                     /gene="trxB"
                     /locus_tag="VH800_000125"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEQ8361225.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFSS"
     gene            complement(39574..39798)
                     /locus_tag="VH800_000126"
     CDS             complement(39574..39798)
                     /locus_tag="VH800_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEQ8361226.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(39902..40645)
                     /locus_tag="VH800_000127"
     CDS             complement(39902..40645)
                     /locus_tag="VH800_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361227.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            complement(40645..41448)
                     /locus_tag="VH800_000128"
     CDS             complement(40645..41448)
                     /locus_tag="VH800_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8361228.1"
                     /translation="MTSVFLTSGWAFYDYLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(41643..42986)
                     /locus_tag="VH800_000129"
     CDS             complement(41643..42986)
                     /locus_tag="VH800_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8361229.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKDSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            complement(43144..44154)
                     /locus_tag="VH800_000130"
     CDS             complement(43144..44154)
                     /locus_tag="VH800_000130"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEQ8361230.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(44156..46411)
                     /locus_tag="VH800_000131"
     CDS             complement(44156..46411)
                     /locus_tag="VH800_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8361231.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(46415..46738)
                     /gene="ftsL"
                     /locus_tag="VH800_000132"
     CDS             complement(46415..46738)
                     /gene="ftsL"
                     /locus_tag="VH800_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEQ8361232.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(46743..47756)
                     /gene="rsmH"
                     /locus_tag="VH800_000133"
     CDS             complement(46743..47756)
                     /gene="rsmH"
                     /locus_tag="VH800_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEQ8361233.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(47970..48209)
                     /locus_tag="VH800_000134"
     CDS             complement(47970..48209)
                     /locus_tag="VH800_000134"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361234.1"
                     /translation="MTNEREKEEAKVTLEELLHQIQVIHLELKIVRNWGYFVFFGDGM
                     LVSWIKRRNNEQGQPIINRLTSYSSKLPKIAGRRR"
     gene            complement(48229..49479)
                     /locus_tag="VH800_000135"
     CDS             complement(48229..49479)
                     /locus_tag="VH800_000135"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEQ8361235.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDIATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     YTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(49472..50293)
                     /gene="proB"
                     /locus_tag="VH800_000136"
     CDS             complement(49472..50293)
                     /gene="proB"
                     /locus_tag="VH800_000136"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEQ8361236.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAYYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVANITQEIIASAGGAGSKF
                     GTGGMLSKVQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVRHD"
     gene            complement(50358..51986)
                     /locus_tag="VH800_000137"
     CDS             complement(50358..51986)
                     /locus_tag="VH800_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361237.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMI
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVVQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKVKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLMDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGDGQWLTMGLIFGNLIVAGVLGFGAVIIANIIQQ
                     PLLISILLSCLILMVLGLAQLWIQKTFWKSLERL"
     gene            complement(51991..52725)
                     /locus_tag="VH800_000138"
     CDS             complement(51991..52725)
                     /locus_tag="VH800_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361238.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            complement(52759..53025)
                     /locus_tag="VH800_000139"
     CDS             complement(52759..53025)
                     /locus_tag="VH800_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8361239.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASLV"
     gene            complement(53218..55203)
                     /gene="tkt"
                     /locus_tag="VH800_000140"
     CDS             complement(53218..55203)
                     /gene="tkt"
                     /locus_tag="VH800_000140"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEQ8361240.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLSKGAYILSEAKGDLDGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     SGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(55421..56065)
                     /gene="fsa"
                     /locus_tag="VH800_000141"
     CDS             complement(55421..56065)
                     /gene="fsa"
                     /locus_tag="VH800_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8361241.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(56191..57690)
                     /locus_tag="VH800_000142"
     CDS             complement(56191..57690)
                     /locus_tag="VH800_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8361242.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMDQETDFSQQLSDDVLALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(57680..59026)
                     /locus_tag="VH800_000143"
     CDS             complement(57680..59026)
                     /locus_tag="VH800_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8361243.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFDYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDADLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(59135..59836)
                     /locus_tag="VH800_000144"
     CDS             complement(59135..59836)
                     /locus_tag="VH800_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8361244.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAAFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAVLAVLLFQVMS"
     gene            complement(59838..61676)
                     /gene="glpO"
                     /locus_tag="VH800_000145"
     CDS             complement(59838..61676)
                     /gene="glpO"
                     /locus_tag="VH800_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEQ8361245.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFERDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGHQEG"
     gene            complement(61692..63218)
                     /gene="glpK"
                     /locus_tag="VH800_000146"
     CDS             complement(61692..63218)
                     /gene="glpK"
                     /locus_tag="VH800_000146"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEQ8361246.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            complement(63579..63971)
                     /locus_tag="VH800_000147"
     CDS             complement(63579..63971)
                     /locus_tag="VH800_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEQ8361247.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(64098..64355)
                     /locus_tag="VH800_000148"
     CDS             complement(64098..64355)
                     /locus_tag="VH800_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEQ8361248.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(64509..66548)
                     /locus_tag="VH800_000149"
     CDS             complement(64509..66548)
                     /locus_tag="VH800_000149"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEQ8361249.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGSFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGAV
                     LALAAKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYANKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAAAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAGDQALKNNRLAILSDLVSKAKTIVAFNQLNTK"
     gene            complement(66926..67843)
                     /gene="glyQ"
                     /locus_tag="VH800_000150"
     CDS             complement(66926..67843)
                     /gene="glyQ"
                     /locus_tag="VH800_000150"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8361250.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            complement(68215..68748)
                     /locus_tag="VH800_000151"
     CDS             complement(68215..68748)
                     /locus_tag="VH800_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEQ8361251.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(68880..69719)
                     /locus_tag="VH800_000152"
     CDS             complement(68880..69719)
                     /locus_tag="VH800_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEQ8361252.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSAIPTPDT
                     TSF"
     gene            complement(69841..70989)
                     /gene="nagA"
                     /locus_tag="VH800_000153"
     CDS             complement(69841..70989)
                     /gene="nagA"
                     /locus_tag="VH800_000153"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEQ8361253.1"
                     /translation="MTCYLKADCFYYPTEVRPAGYLSLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(71107..72738)
                     /locus_tag="VH800_000154"
     CDS             complement(71107..72738)
                     /locus_tag="VH800_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEQ8361254.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADGKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            72940..73662
                     /locus_tag="VH800_000155"
     CDS             72940..73662
                     /locus_tag="VH800_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361255.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(73791..74633)
                     /locus_tag="VH800_000156"
     CDS             complement(73791..74633)
                     /locus_tag="VH800_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8361256.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLIKLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            74926..75483
                     /locus_tag="VH800_000157"
     CDS             74926..75483
                     /locus_tag="VH800_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8361257.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(75519..76343)
                     /locus_tag="VH800_000158"
     CDS             complement(75519..76343)
                     /locus_tag="VH800_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8361258.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALVAQKD"
     gene            complement(76345..76962)
                     /locus_tag="VH800_000159"
     CDS             complement(76345..76962)
                     /locus_tag="VH800_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEQ8361259.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLMARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(77159..78136)
                     /gene="lacD"
                     /locus_tag="VH800_000160"
     CDS             complement(77159..78136)
                     /gene="lacD"
                     /locus_tag="VH800_000160"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8361260.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(78183..78636)
                     /locus_tag="VH800_000161"
                     /pseudo
     CDS             complement(78183..78636)
                     /locus_tag="VH800_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(78646..79161)
                     /gene="lacB"
                     /locus_tag="VH800_000162"
     CDS             complement(78646..79161)
                     /gene="lacB"
                     /locus_tag="VH800_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8361261.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(79176..79601)
                     /gene="lacA"
                     /locus_tag="VH800_000163"
     CDS             complement(79176..79601)
                     /gene="lacA"
                     /locus_tag="VH800_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8361262.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(79841..81292)
                     /locus_tag="VH800_000164"
     CDS             complement(79841..81292)
                     /locus_tag="VH800_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEQ8361263.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYAARNHLPVFVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGPQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            complement(81318..81623)
                     /locus_tag="VH800_000165"
     CDS             complement(81318..81623)
                     /locus_tag="VH800_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8361264.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPIVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            complement(81616..82089)
                     /locus_tag="VH800_000166"
     CDS             complement(81616..82089)
                     /locus_tag="VH800_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8361265.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            82326..83096
                     /locus_tag="VH800_000167"
     CDS             82326..83096
                     /locus_tag="VH800_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8361266.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            complement(83300..83503)
                     /locus_tag="VH800_000168"
     CDS             complement(83300..83503)
                     /locus_tag="VH800_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEQ8361267.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLIKRALKDTKFELYKWS"
     gene            complement(83517..85748)
                     /locus_tag="VH800_000169"
     CDS             complement(83517..85748)
                     /locus_tag="VH800_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEQ8361268.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGRAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATVVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLT
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNAALMGILGIDLSCVQSVCAKASEKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRVTM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(85748..86182)
                     /locus_tag="VH800_000170"
     CDS             complement(85748..86182)
                     /locus_tag="VH800_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEQ8361269.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNFLTSYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLYHL
                     PMTLEEIGAFQELLEVKKENAVLEVPCNCLPGQCHCQRKETY"
     gene            86354..87340
                     /locus_tag="VH800_000171"
     CDS             86354..87340
                     /locus_tag="VH800_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8361270.1"
                     /translation="MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEI
                     PEYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTP"
     gene            complement(87474..87824)
                     /gene="rbfA"
                     /locus_tag="VH800_000172"
     CDS             complement(87474..87824)
                     /gene="rbfA"
                     /locus_tag="VH800_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEQ8361271.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRDLDNKS"
     gene            complement(88029..90890)
                     /gene="infB"
                     /locus_tag="VH800_000173"
     CDS             complement(88029..90890)
                     /gene="infB"
                     /locus_tag="VH800_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEQ8361272.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(90910..91212)
                     /locus_tag="VH800_000174"
     CDS             complement(90910..91212)
                     /locus_tag="VH800_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEQ8361273.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            complement(91205..91501)
                     /locus_tag="VH800_000175"
     CDS             complement(91205..91501)
                     /locus_tag="VH800_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEQ8361274.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(91517..92674)
                     /gene="nusA"
                     /locus_tag="VH800_000176"
     CDS             complement(91517..92674)
                     /gene="nusA"
                     /locus_tag="VH800_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEQ8361275.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATAVEEPVVDDVMTAEEV"
     gene            complement(92849..93385)
                     /gene="rimP"
                     /locus_tag="VH800_000177"
     CDS             complement(92849..93385)
                     /gene="rimP"
                     /locus_tag="VH800_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEQ8361276.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(93630..93809)
                     /locus_tag="VH800_000178"
     CDS             complement(93630..93809)
                     /locus_tag="VH800_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8361277.1"
                     /translation="MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGE
                     VVTDEKVEEVLMELE"
BASE COUNT        28040 a        20021 c        16728 g        29067 t
ORIGIN      
        1 aaattctctt atgataccat gttcgtcatg agttttttat tgttaaatgg aaaaagaaaa
       61 aaacgcgctt tatattctga aaacgcgctt tttcatattt ttttgagaat ttctagccca
      121 gaattgggac taatcttttt tcaaactaat tttacgtaag atttacttaa agaggaactg
      181 taatagatac ttttgttagc ataatgactg tcgtatctat cacttaatct cattttcatc
      241 atgtcacctc taaacatgaa tagctttttc ccacttttaa aatacgtata atcatccctg
      301 taggttttag ttgtgaacta tttagcttct attaatccta ggtttccatc ttcgcgacgg
      361 tataaaatgt ttgttgcgcc atcttcagaa tcagtgtaga taaagaaatc atgtcccaat
      421 agttccatct gtaaacgcgc ttcttcaaca tccattggtt ttaatgtcac atttttagta
      481 cgtacaactt gtacttctgg tatctcatcg acttcttcag cttcaaactc agttgtaaag
      541 acttgaccag ttggaacctt ttcgcgatgt tttttagcaa ttttggtttt attttttcta
      601 atttggcgtt cgatcttatc aacaactaaa tcaatagagc cgtacatatc ctgtgaaaca
      661 tcttcagcac gaagggttac tgaatctaat gggatcgtta cctcaacttt tgaagatctc
      721 tcccgataaa cttttaaatt aacacgtgca tctatttctt ggtctttagc aaaatatttt
      781 tcgattttag taagctttga ttctacataa tcgcgaatag cttctgtcac ttcgatattt
      841 tctccacgaa tactgaactt aatcatagga tacctctttc tcgcgcttga agcgcttact
      901 ttatctttaa tactattata ctgctttcat gaaaatttgc aagttttaac gtgcaattga
      961 caaactttta atgtcactat ttgctacttt agccaattgt tttctaagag cgataattgt
     1021 actaccagta gtataaatat catctactat aaggatttta tcaggaatgt ttgatacttt
     1081 tagtagtcga taagattttt ctactaataa tctctctttt tttgttctgg aagattggtg
     1141 agtattatct agcttttcaa aaagagaaag gtagctaaca ttagctgcct caagaatagc
     1201 gctcacttga ttaaattgtc tttctcgaaa acaaccggga cttacaggaa ccgggactgg
     1261 gatatagcct ttatagtact tggtgataac atcggcaagt tctactgcaa aaacttttct
     1321 taataaatag tctccttgaa acttatattg actgaagtat gctttcatag cagcattata
     1381 acaatataag cttctatgat ttacattgta tcctttgttt tcccatttta gacaatctcg
     1441 acaagctatt atatctgagt ttgcacaaca tgtcgcacaa acactttttc ctatcttttg
     1501 aaagcttttt tgacattgtt gacaaatcgg tgaagagata cgtcttaaaa agatgatttc
     1561 tgtaatactt attggtgttt gactaatttg ttgacatagt agacagatca tgcgaatacc
     1621 ctttataatt catttcttta atctcttttc ttgctagtag cattgcttta ctgatacctt
     1681 catgaaagaa atataacgtt ccgtctggtc tgtctataga tcttccaact cgtccagcaa
     1741 tttgaacaag actttgggaa ctatagacac gatgatgaga cccaagaaca aaaacatcaa
     1801 tttggggaaa tgtcacaccc ctttctaaaa ttgatgttgt aattaaaatc gtttttttcc
     1861 cttgacgaaa agctgtgata tcttctttcc tgttttgtga ttgactagaa acacaagcta
     1921 tttgttcggc gggcaataac tcttttaaga ttgctgtaac agattctgcc attataatag
     1981 tgggtagaaa aattaaaagg ggatagcctg tttttctttg tttttttaag tattttaaaa
     2041 ttttaagagg aagtttttgc cgatgtatca ttttaaatag attaaaactt cttataaatt
     2101 ttggaataac taatggccta ttatgaaagc gtctcgccaa tgtcagcttg actacttctc
     2161 ccttgtttac ctttctttct aaagttctag ttgaagttgc agttaataaa atctttgcgc
     2221 caccttcttt taaagcctga cttgcagcat aatgaagttg aatattattt acaaaaggga
     2281 atgcgtctac ttcatcaata attaagagat caaaagcctt gtgaaatttt agcagctgat
     2341 gcgttgtggc tactataata ggagctcttt gataaggaag agactctgcg tgcattaaac
     2401 agatgctgca ggagaaggct tgggataaac gagtagccac ctctacacaa acatctactc
     2461 ttgggctggc aatgcaaacc cagccacctg tgttaattac cgcctcaatc gcagcataaa
     2521 tcatttctgt ttttcctgca ccagttacag catgaactaa tgttgttttt tgattttgca
     2581 tattgattaa taattgttgg gaaatcatct cttgataagc agttagttga ccgccccaaa
     2641 ccagataatt accttttgga aaatgcatag gtgggatagc atagagcaat ttatctgatt
     2701 gatttcgtcc aaagacaaga caaaatcggc aataataggc tccacttggc aatcgtgctt
     2761 cttcatcaag ctgatagtga caacgttgac aaatcatttt tcctctcaat attactacac
     2821 tttttaaagg ttgagcaagc tgctttgctg aatctggtaa ctggctttct agcaacaacc
     2881 gtccataact attttcaata gactccatac tttattattc gctttttttt gctaattttt
     2941 atcttttctt gtacaatttt tttatggaac attttaagac aatcaaagcc agtggttttt
     3001 tcgaagaaag tattaaaaaa tctcgtttca tttgtcatat caaacgagtg agcactgaag
     3061 aagatggtaa gaattttgtt aatgctatca aaaaagaaca ttacaaagct aatcattcct
     3121 gctttgcgat gattatcggt aacaacagac agatcaagcg ctcaagtgat gatggtgaac
     3181 cttcaggaac tgctggaata cctatccttt ctgtgttaga aaagcagtgt ttaacaaatg
     3241 tagtagttgt ggtaacgcgt tactttggtg gtattaaatt aggaacaggt gggttaatca
     3301 gagcatactc taacatgacc gcaacagcta ttaaacgatt tggcatcatt gaagttaaac
     3361 agcagatagg actagaaatc acactttctt atccccaata tcaactatac tctaacttgc
     3421 tagatcaatt ggctttaacc gaaacagaaa ctaagttttc agacacgata aagacaacac
     3481 tttattgtga tactgaacgt gtggaaaatc tcattgatac tttaacaaat tattatcatg
     3541 gtcagataag ctgtgagaaa atcggatcca aagttattga attcccctgt gattaatcat
     3601 caacaaaagt gatatggctt tattatcaga gtgatagtaa atctgtattt tactttaata
     3661 atatctctcc ttatacttaa atacacagcg tatttatttt gtatcaagaa aagaggctaa
     3721 actatgacta aaatttacaa aactataaca gaattagtag gtcaaacacc tattatcaaa
     3781 cttaaccgtt taattccaaa cgaagctgct gacgtttatg taaaattaga agcttttaac
     3841 ccaggatctt ctgttaaaga tcgtattgct ttatcgatga ttgaagctgc tgaagctgaa
     3901 ggtctgataa gtcctggtga cgttattatc gaaccaacaa gtggtaatac aggtattggt
     3961 cttgcatggg taggtgctgc taaagggtat cgagtcatta ttgttatgcc cgaaactatg
     4021 agcttggaaa gacggcaaat cattcaggct tatggtgcag agcttgtctt aacacctgga
     4081 gcagaaggta tgaaaggggc tattgcaaaa gctgaaactt tagcaataga actaggtgct
     4141 tggatgccta tgcaatttaa taaccctgcc aatccaagca tccatgaaaa aacaacagct
     4201 caagaaattt tggaagcttt taaggagatt tctttagatg cattcgtatc tggtgttggt
     4261 actggaggaa cactttctgg tgtttcacat gtcttgaaaa aagctaaccc tgaaactgtt
     4321 atctatgctg ttgaagctga agaatctgct gtcttatctg gtcaagagcc tggaccacat
     4381 aaaattcaag gtatatcagc tggatttatc ccaaacacgt tagataccaa agcctatgac
     4441 caaattatcc gtgttaaatc gaaagatgct ttagaaactg ctcgactaac aggagctaag
     4501 gaaggcttcc tggttgggat ttcttctgga gctgctcttt acgccgctat tgaagtcgct
     4561 aaacagttag gaaaaggcaa acatgtgtta actattttac cagataatgg cgaacgctat
     4621 ttatcgactg aactctatga tgtaccagta attaagacga aataaaaaag ggtttggaac
     4681 tactaaggtt ccagactctt tttagtgttc ttttttaaaa actgcaggct ttcttcaatc
     4741 cactgaggta actgctcttc aagtggccta aagccaatct tgtgccgact gttggaataa
     4801 cgatgacgat ggaaaaaatg ctgtttttct tctgctaagg tccgcataga taaacttggc
     4861 tttttactat attcatcaat atcaattact tgtactaaaa cctggttgcc tatagccaat
     4921 aattgatcaa tatcgtcaat aaatcccgtt tttatttctg aaatatgaat gagacctgtt
     4981 gtcccatttt caagggcaac aaaggctccg tatggtttaa tcccagtgat ggtgccatgc
     5041 agtttgtcgc caattttcat tagtcaaata cctcgattgt ttcaatgata acgtcttctt
     5101 taggtttatc ctgtgcgcca gtttcaacgc cagcaatcaa atccaaaact tggaatgaag
     5161 tttcgtccac aagctgacca aagaccgtat gacgacgatc aaggtgagga gttccaccat
     5221 ttgcagcgta agaagctgca attggagccg gccaaccacc acgttctagt tcttttttgg
     5281 cataaggaat cttactattt tgaacaataa agaactgact gccgttagta tttggtcccg
     5341 cattagccat cgacaaggcc ccacggagat tatagagttc atccgaaaat tcatcttcaa
     5401 aactttcacc atagatggat tgtccacaca ttcctgttcc tgttggatcg cccccttgaa
     5461 tcataaattc aggaataata cggtggaaga taatcccatc atagtaccct tctttagcca
     5521 aacctaagaa attggctact gttttaggag catgatctgg gaacaagacc agggtcatat
     5581 cgccatggtt tgttttaatg gttgcttttg gtcctttatg gtttggcaaa tccaattgtg
     5641 gaaactgtaa ttctttgtca atcaatccta attcctccaa ggcatataaa atgccatctt
     5701 cttcaacttt ttttgtgata aaatctgctt tttcttgcag taatggatgt gatactccca
     5761 ttgcaatact gataccagca tagtcaaata actctaggtc attgagttca tctccaaaaa
     5821 ccaaaatatt ttcaggtttt aatcctaaat ggtcaactac ttttgaaaca cctagcgctt
     5881 ttgacgtacc tttcaagaca acatctgatg agttatcgtg ccatctgacc aaacgaaggt
     5941 gctctgctaa ttcagcaggc aactgcaagc catctccctt gtcctcgaaa gtccacatct
     6001 ggtaaacatc atgatactca ttataatccg gacagacctc tagttgagcg tagacattat
     6061 caatagcatt gctaatcatg tcatttcgag cggacaacac cgcttcatga cgacccgcca
     6121 ttccataaaa aatgcccata tcatccgccc attttttata ggccacaaca acatctgctg
     6181 gaatcggagc ttggaaaata atagttttag catcgtcttt gacataagct ccatttaatt
     6241 tgacacaata gtcagcatgt aaatcttgaa cttcttgtgg aacaccgtac cgagcgcgac
     6301 ctgaagcaat accaaccaag atgccttttg ccttcaaagc cttaaatact ctttgaatcg
     6361 actcaggcat ataacccgta tctttgaccc tcaaggtatc atcaatatca aagaacacca
     6421 ttttgatttt tttagctttg tattttagtt ttgcgtccat actttcctcc aatttgctat
     6481 accctatatt atagcattaa ttatcgtctt gggggactaa atgatgtcga aaagcataga
     6541 caaccgcttg ggttcggtca ccaacttcta acttggctag aatattggac acatgtgttt
     6601 tgacggtttt taaggaaata aagagttcat cagcgatggt ctgattatca taccctttag
     6661 ctaaaaggtg taaaatgtca tactcacgcg ctgttagttc ctcatgcaag tcagggtgtt
     6721 gatcatgcgc cttaattttt ttgtcaactt ctgtttcaat agctaactct ccctttgaaa
     6781 ccttgcgaat ggcatttaaa atttcagccg cactcgatgt ttttaacata taacccttcg
     6841 ctcctgcatc aatgacaggg tatatctttt cattatctag ataggaagtt aacacaagta
     6901 ccttagcctc tttccatttt tttaggactt ctaaagttgc ctcaacaccg cctaactctg
     6961 gcatcactag atccataacc aaaacatctg gcttcaaagc caatgccaaa tcaacccctt
     7021 cacgtccatt agaggcctca ccaacgacat caatatcagc ttgtaaattc aaaaaactct
     7081 tgagtcccat gcggaccatt tcatgatcat cgaccaatat cacttttatc ttactcatcg
     7141 tcatctccct tcactatcgg cagtctaata tccatggaaa ctcctttgcc tttttgacta
     7201 attaaatgta ggtttcctgc taaatcattg acacggtctt caatattctt cagaccataa
     7261 ctcaaatccc ttacctgatc catatcaaat cctacaccat catcaatcat cttcaattgt
     7321 aattctgttg aggtttgatt gagataaact tcaattcgac tagctttagc atgttttaac
     7381 gtgttgctaa tgaattcttg ggcaattcta aaaagattat cttccattgt tttaggaagc
     7441 tgagcaatgg tttccttata aatgacttca atatcacttt tatctgttaa ttccttaaga
     7501 atcatatgaa ggccctcaga taaagtccga ttagctagct cggtaggtct aagatgcaaa
     7561 aggagaatgc gtagatcatt ttgagcattt tgcaacattg cttcaaccgt tgttaactgt
     7621 gtttgtaatt gtgttttgtc cagttgttcc aaactcatcg aaattcctga taaaatcaat
     7681 gacgaagcga atagctcttg actgactgtg tcatgtaaat ctcttgcaat tcgtttgcgc
     7741 tcttgtttta caacttcttg gctatcaaga atataagcac tttctttctt ttgcatgtta
     7801 gcagtcaggt gagacatttt tttagaaagt cgacttaaat tagtattgat ttctgatgtc
     7861 tcatctagat agagtcgtcg attattgaga atatatttta gattttggtt gatgttacgc
     7921 ttactgttat catccataat aatccacaat aacaacaata ataaagtcac agaaacaatc
     7981 aacaataaaa tcgaaaaccc tagacgttcg acctgccata aatgattgcg aaggtagtta
     8041 aaagtgattc ctaaattatc catgaccaca aaaacaatag ataaaatggt aatggttgag
     8101 tagagccaaa caagagcata gtaacgtttt ttcatcgcct atccacctca acatttccgg
     8161 caatagttgt aacgataatt ttgacttttt taagggattg gttatccgtt tcttttaact
     8221 taatagattc gttgcgcaaa tcatattgct gacatctaaa aaaatcaacg cttccgtata
     8281 tggaactaac atctaaagta acagtgacat caataggtac caatatagtc gtatttccaa
     8341 aaattttacg tatcacaatg atattatcca ttcctgtcac aataacattg gttaagtcaa
     8401 ccgtgtcatt tcctgagatt cgaatgatgt taatgtcatc aaaacaataa taatcacttt
     8461 cataattagc agtaccaatc cattgatgct tggtattgtt cacttcaatc ttttcttcct
     8521 tgaaacgaat caaggcaaag cgattcttct ttttgacttg tgaaaaatgg ttaatgaaaa
     8581 tgtaaactat ccccaaaaga acagccatga taatgtaggg attaagcatg aaaattaaaa
     8641 aaagaaacaa taaactgaca gttagtaaaa aattattgcg gctatcttgg ttataaaagc
     8701 gtaatgctaa taagataaga actagaatta ggataaaact tgataaatca ttatccaaga
     8761 ttgtcatgat acccatagct agcagtatac actcgataag taaaaagaat tgaaattttt
     8821 tcattagttt ccccttattt ctttgtattt tatcagaatt cctggaaaat tgcatcttta
     8881 tatgacgagt agttaaaaag aatagttagt ggcatgccag taaaacatga gactaactat
     8941 tctttgttaa ggtgtttgag aagtagtttc tgatgggctt aattcagtgt tgctacctgg
     9001 tgcagtacta tcatttattg aagaactgtt tgaacttgac gttgaactcg atgagctact
     9061 agaagagtgt gtttcttctg gataaaggta aagactaatc tctcctttat cagacaaact
     9121 caaagacgtt ccatagtaag gagattgacc actgacaata gctttagaac taggagaatg
     9181 aattggcaca aagcccgttg ctgagctaga gcttggcaca taagctttta ttctagatgc
     9241 atctatacct aaagctgtta aggtattgac tgcatctgca taactatatt ctgttaccat
     9301 aggcatagtg atcgtatcac taacagcaac actgagcgta attttagact ttccgtttgg
     9361 attaaattta tcacccgcac ttggcgattg actgatgact gtattttcag gatattcatt
     9421 agttacaatg cgctcaattt tgatttttga ttttggaaca ccataagttt ctatcaaact
     9481 attcatagct tcttgataat ctagtccttt gtagttttcc atgtcaaaac ctttgtttcc
     9541 aattgacaca taaagcgtaa tgcttgagcc ttgcctctta gctgttcctg ctttaggatc
     9601 tgttctaact acatttccct cagcaaccgt atcactctca atttgcctga ttttacccac
     9661 ttttagccca acatcataca gttcttgttt ggcaacttta agactagtgc ctgctacatt
     9721 aggaactttc acagaagttg gtttagttag tataagataa gtaaagagtg ctacacctac
     9781 aataaagaaa gaaaaaagaa ttttgaataa agtacctaaa aaacgaccac tttttttctt
     9841 tttggtgggg ggctgtaaag catctgtttg attagtttga tctaatcgac tttcctgtgt
     9901 taacactgtt ggggtagggg gagacaattt tacagaagcg gtgggacctg aggccacttt
     9961 ggggaggggt ttggtacttt caacattctc aaagataatc ttacgctccc gactacgatt
    10021 ataactaagc gccgtcatta agtcacgact catttcaaag gttgacccgt aacgatcact
    10081 taatttcttg gctgttgctc gaataacaac attctccaaa gcttgtggca cattgtggtt
    10141 ctcctcgata atagatggaa gaggcttttg aaaatgttgc aaggcaatcg taacagcact
    10201 atcgccgtca taagggatat ggcctgtcaa catctcaaag agcataatcc ccatcgcata
    10261 aatatcactt tgaatcgtcg ctttggagcc gcgagcctgt tctggagaca agtaatgaac
    10321 actgcctaac atcgaattag tttgtgtcaa gcttgtttct gcaaaggcta ctgcgatgcc
    10381 gaaatcagtt actttgacaa caccctcctt agttagtagg atattttgag gttttaaatc
    10441 tctgtgtaca attccttttt ggtgggctaa agtcatagca gaaaggactt cttccataat
    10501 tctaaccact tcattattag ataatggagc atgattttga atgtatctct ttaggtcagc
    10561 accatccaca tattccatta ctaaaaattg ctgtccgtct tcttcaccta tatcccggat
    10621 ggcaacaata ttgggatggt tcaattcagc catggcccgc gcttctcgtt ggaaacgcgc
    10681 aactgctacc tgatctgttt gataattggt acgcaagacc ttgattgcaa cgtcttcatt
    10741 atccaagatc aagtcatttg ctaaataaac atccgccata ccaccgcggc caatagattt
    10801 cagaatgcga taacgaccag caaataattt gccaatctga atcattcgac gtcctcactt
    10861 tcgttatgaa ccaaagcgat tgtaatatta tctaggcctc ctcttaggtt agctaagtca
    10921 atcatttctt ggtttttttc atcaagacta accttactgc ccaagatagt cacaatttca
    10981 tcatttgaaa tcatattggt tagaccatca ctgttaatga caagataatc ccctggctcc
    11041 aaaaccctca ctcctaaatc aggctctact ggggaagctt gaccaataga ttgagtgata
    11101 atatttcttt gtggatggct agcagcttct tcttctgtga tctgtcctgc cttaaccaac
    11161 tcattcacta aagaatgatc actggtcaat aaggtataat gcccatcatg gacaagacca
    11221 atccgtgaat caccaatatg agcataaatg gcgctagatt caactaaagc tactgcttca
    11281 acagtcgttc ccattccttt aaagtcttct gattggccta gatcataaat ccgttgattt
    11341 tctgactgga tagtttcaaa taaccaatct ctaatctgac ttaactctgt gaagtctgtt
    11401 tttacccatt ctcttcccag gtctgtgact gtcatctcac tggcaatatt tccagctctg
    11461 tggccaccca taccgtctgc taaaatcact aaagtgatgc cttttttatt atcaaactta
    11521 ttgataaaat cttgattgtt tgagcgtttt tgcccaatgt ctgtttttaa tgaaatcttc
    11581 atacgttttt tctgactcag tcagtttcct cctaaaatac tacaagactc gtctgacttg
    11641 tccaataaag aagccatcag tctggtattg ttctggtgtg ataataagat aaccatcctt
    11701 gacaatatct gcttgtgtat ggttcagttt tacttgttca aaattaggat gactctgtaa
    11761 aaatgcttcg atgacttgac gattctcctc atcaaaaata gtgcaagtac tgtatgttat
    11821 tataccacct ttacgcaagg tttgacaaac actagacaat atctctagct ggatagcttg
    11881 cagagcattg aaatcttgac tttctttatt atatttgata tcgggttttc gacgaatcaa
    11941 accaattcct gagcaaggag catccaccaa aatcttatca aagctatcct tttcaaaatg
    12001 acgatgaacc tctctggcat ctagttttct tgtctcaatg ttatcagcaa ctcctaagcg
    12061 gttagcattt tccttcacca actctagttt atgatcatag agatctaagg caataacttt
    12121 acctgttttt aagtaagatg ctatatgaga ggtcttgccc cctggagcgc tacacgcatc
    12181 aagaattatg tcgtcaccgt caatgtttaa agtaggagct acaagctgac tgctttcatc
    12241 ttgaatagtg atgtccccat ttgtgaaata atcactggct gcaaaatgac ctgacgcttt
    12301 ggttaaacca gttgctgata aaagggaacg ttctgcatct aaagcctcag caacttcctc
    12361 tagcttcaaa gggtctgtca cgcgaatact agccttacta cgcacaaata aactttccat
    12421 gatggccact gatctgtcag aaccaaattg gtcttctaac tttttaacca accaaacagg
    12481 cagtgaatac ttgaccgaat aatacttatt tcgacgctta attgtttcca tatctgggag
    12541 aggatggctg gtgaattgac gtaaaatagc attgacaaac ttctctgcac cttttttatt
    12601 gccacgattt ttggcaatac caaccgcatc gttaacaatg gcatgcgctg gtaacttatc
    12661 taaataagtc agttgataaa gactgagcat aaggagataa taaacccatt tgtccaattt
    12721 atctcggtct ttgacataat gggctaaata ccattccaag ctaattttac gtgaaacggt
    12781 accatataca atctcagtta atagagctct gtccttagca gataaagctt tattgcttag
    12841 ttgctgatta agcgctatgt ttgtgtaagc cccctgatca aaaatagctt caatgacaag
    12901 gagggctttg cctcgcgtac tttttttcca attatctgcc aatgatgtcc cctacttcaa
    12961 gttttctacc aatgccgttt aaaaagtcta ttattgacat tttaggttta ccagccggtt
    13021 gcacaacgat caaggacaaa gcaccttgtc cagtagctat taccaaagat tttttggttt
    13081 tgacaacaac ttgtccaggt aatccctctc cttcagctag ttgagcttcg taaattttta
    13141 aacgttgccc ctctaaaaac gtatgcgcta ccggccaagg gttcatacct cgaatatgat
    13201 tgaacacttc ttgattagac attgtccaat ctaatttttc atgttctgga gagatattag
    13261 gtgaaaaagt agcttggctg tgatcttgag gaataggttt taattctcca gaaagataag
    13321 ctggcaaact atccaaaagt aagtctcgac caatgatggc taatttctca aaaagagtac
    13381 ctacattatc ggtttcaaga attggagtgc ttgctttagc gaccatgtca cctgcatcca
    13441 tttctttaat catttccata atagtaacgc cggcctcttt atctccattc ataatagcat
    13501 aatggatagg tgctccacct cgatatttag gtaacaatga tgcatgtaca ttaatagcaa
    13561 atgaaactga atcaagtaat attgttggta aaaattggcc aaatgctgct gtaataatac
    13621 catctgcacc aagtcccata atctcaatga gttcttgaga gcctgataat ttttccggct
    13681 gatagattga tattccatgc tcaagagcta attgctttac aggtgttacc ttaatatctt
    13741 ttttgcgtcc aacagctcga tcaggctgag taaccactcc taaaatctca taggcaggat
    13801 tatctagcaa gcccttcaat acagttgctg aaaattgggg agttcccata aataataatt
    13861 ttatcatgac tttcctcttt gtatttttat tatatcataa ctgatcatcc tagatttagt
    13921 gatttacctt ataaaaattg ttgcggttca caatcaataa ttagttttaa atgacgatta
    13981 tctgcttctt gactccaatc aagaatacga ttgagcgtct cttctaggtt atcttcaaaa
    14041 cggtatttta acaaaatttg atagtggtat aaattgtgtg ttctagcaat tggcttagga
    14101 gtcggtccta atattttaat attatccgat aagtgactct ttagcagttc tgtaacttga
    14161 taagcttttt ttacaaccga tgcttctaaa cgatgcgaaa gcgtaatacc cactgtaaag
    14221 tagtaagggg gataagccat ttgatgacga atagacatct cataacggta aaaagcttca
    14281 aaatcttgtt tcttagctaa ttgaatagca tagtgatcgg gattataagt ttgaatcaag
    14341 acctctcctg gcttatgggc acggcctgcc cgaccagcaa cctgtgttaa caattgaaac
    14401 gttttttctg acgctcgaaa atccggcaaa tttaaggaag tatctgcatt tagtacccca
    14461 actaaagtca catttggaaa atccagtcct ttggcaatca tttgcgtccc taacaaaata
    14521 tctgcttcct ggcgaccaaa actatctagt atggttttgt gacttctttt ttttcgtgtg
    14581 gtgtcaacat ccattctcaa gatcttagct tctggaataa ccccttgcaa ttcatcaaaa
    14641 gctttttgag ttccagtgcc ataatagcgg atactattgc tatgacactc aggacaagta
    14701 attgggatag gtttttgaaa cccacagtaa tggcaattca tagttttagt atccatgtga
    14761 agggttaaag agatatcaca gttgggacat ttgtccacat aaccacagtc ccgacacatc
    14821 acaaaactag aataaccacg tctatttaac attaagacaa cttgttcttt tttaaccaaa
    14881 cgttctttaa tcttatcaat caaatatggg gtaaaattac taactgcttg ctgtccaata
    14941 taatcacgaa aatcaacaat cgttacttct ggaatcttag caagagggtt tgctctttgc
    15001 gttaattgaa taaaatgata gacaccctta ctagcccttg ctcggctttc aatacttggc
    15061 gtagcagagc ccataaccac aactgcttga tggtgtttag ctctgagcag ggcaacctct
    15121 ctggcatggt atctagggtt gctttcttgt ttataggttg attcatgctc ctcatcgata
    15181 ataattgcac caatccgctc tagtggggag aaaatagcag agcgggcacc aaccacaacc
    15241 ttagcctgtc ctgtttttat cttgcgccac tcatcaaact tttcaccatc tgataagcct
    15301 gaatgcataa tagccacttg ctttccgaaa cgggaaataa aacgagaggt catctgagga
    15361 gtcaacgaaa tttctggcac taaaacaatg gctgtcttat cctgttttaa aaccgcttcg
    15421 atgatatgaa gataaacttc tgtcttaccc gaacctgtaa tcccttcaat caaaaaaggt
    15481 ttactcggtt tcccaatttg ttcaacaatt tcagtaacag ctgacgcctg ctgttcattt
    15541 aaggttaaaa aagaagatgg tttgatctgg tcaaaatagg actcactgcg atcaattgga
    15601 cgttcgtcaa tacgaattaa gtgatttgtc acaaagtaag ccaccacatc tctagaaaag
    15661 gcttgataaa gcgttgcaag tttagcttcc ttcgtatggg ttagcagata gtcttttaat
    15721 aattgacgct ttttggcacg actagagatg ggatgtaccg ctaaggcgtc taagtcgacg
    15781 tgataatatt tttctgtctt taggtttttc ttgtctttgg ctaaataact aacagtaata
    15841 tgcccagctt gtatgccctt aagagctatt ttttccttct cgcggtctaa ggtagaatat
    15901 aagacagatg gttttccttc aaaaagaaag tccctatcag acttttttag acctgactct
    15961 ggccttagca ctttatcata gttagagtta agaagattag gaatcattgc ttttaagagc
    16021 gtgattttat aagaaaaaac tgtttttcga agctgatcag caagggtcaa ttgctcttgg
    16081 tttaggactg gctcaggatc taaaacggtc tgaatcagtt taagagagct tgaatcttct
    16141 tggccaaaac caataataaa gccttgcaac aaacgattcc cttttccaaa aggaacatgc
    16201 acacgagaac caagctgcac gagagaaact aactcttttg gaataccata agaaaatggc
    16261 ttgtccgttt gcatcaatgg aatatctaca atcacatgag ctactttttc catttgcttc
    16321 tccttttctg tcatggacat cgtactaaat atgaaaaaat ctaagatttc tgaaacctta
    16381 gattttttct ccttcttctt ctttttcttt ggcaatttgt tctttgattt tacgttcctc
    16441 ttcctctttg gccaagcgtt ctgcctcaat cttagcacgg acagcttcac gtttagctga
    16501 aggatctggg tgaatcacaa cgtttcctga ttcaatttct tcaagtgcct gaagtgttga
    16561 cttcactgat ttaaattctt gagttggagt ggcaccagct tctagttcat gggcacgttt
    16621 ggcttgtaaa atcacaagtg aatacttgga tggtacttta tctaataagg tatcaatgga
    16681 aggttttaac atcataatgc ttactctttt ctatttagct ttaaaggaat tttttgttat
    16741 tttaatcatt ttatcataac gaccaatcac gcgctccaca cgaaagtgtt ctgtctcaat
    16801 gatacgctta acccgctcag ctgccaaggc aacttcatca ttaacaactg cataatcgta
    16861 ttcgcgcata agggcaattt cttcttttgc tctttcaata cgttgagcta tgacttcttg
    16921 actatctgta ccacgaccaa ccaggcggtc ttctaattca tctaaatctg gtggtgttaa
    16981 aaaaacaaaa acaccatctg gtacttttga cttaacctga agagctcctt gaacttcaat
    17041 ttctaaaaag acatcaattc ccttatcaag agtctcatta acataagtta aaggggtgcc
    17101 atagtaatta ccaacatatt cagcatactc tagcatttga ccagttttaa tgagttcttc
    17161 aaattcttca cgtgtgcgga agaaataatc aaccccatca acctcgcccg gtctttgcgg
    17221 acgagtcgtc attgaaaccg aatattcaaa tttatgatct ggcgttgaaa aaatttcttg
    17281 tcttaccgtt ccttttccga cacctgaagg gccagaaaag acgattaaca aaccgcgttc
    17341 agacattgta ttctccttat tagttgcttt ttaatagttt atcaaaaagg ctagtctttt
    17401 tcaagaacat tttcaaaggc aagtcataaa gaaaaagagg ataattcctc tttttctact
    17461 tggcataatc aaccgctctc atctcacgaa taacagttac tttaatattt cctgggtaat
    17521 ctagattgtt ttcaattttt tctcttactt tatgcgacaa aatgacaacc tgatcatctg
    17581 aaattttttc aggttgaacc ataatacgaa tctcacgtcc agcttgtaga gcaaaactat
    17641 tttgtacccc atcaaaactt gtcgcgattt cttctaaatc acgaagacgc ttgatgtaat
    17701 tctccattga ctcattacga gcgcctggac gagccgaact gagagcgtct gctgcagcta
    17761 ctagcacagc gatcacagaa tctggctcca catctccgtg gtggctagca atagtgttga
    17821 caacaactgg atgttctttg tatttacgtg caaattccat tccaatctca acgtgactgc
    17881 cttcaacctc acggtcaata gctttaccca tatcatgcaa gaaaccagca cggcgggcaa
    17941 gagcaacatt ttcacctaac tcaccagcta aaataccagc taacttacca acctcaacag
    18001 agtgacgtag gacattttga ccaaacgagg tacggaattg caggcgtccc atgattttaa
    18061 tcaaatcagg atgaaggttt ggtgcaccaa tctcataggc tgcagcttca ccgtactcac
    18121 gaatacgatt atccatttca agacgatttt tctcaaccaa ttcctcgata cgagctggat
    18181 ggatgcgacc atcagcaatc agagattcca aggtcatacg agcaatttca cgtcgaatag
    18241 gatcaaatcc tgataagata acaacttcag gagtatcgtc aataataacg tcaatgccag
    18301 tcaagctctc taaagtacga atattacggc cttcacgtcc aataattcgg cccttcatgt
    18361 tgtcgtctgg gagatggaca ctggtaatag tttgttcagt cacatactca ccagcaaggc
    18421 gttgcatggc ttgcgctaac aagtccttgg ctgttttaac tgttcggtcc ttgatgtcac
    18481 gttcggcatc tcgaatgcgc gtcgcaattt catgggtcag tttgttttcc gtctccatta
    18541 aaatcacttc acgcgcttct gcaatcgtca tcgcagcaac tttttccagt tctgcttttt
    18601 tctcctcttc aagtttttcc acttgaagtt gccgctcatc aatgtgttta gatttatcgg
    18661 tcagactttg ttctttacta tctagtacct tttctttact tgataggttt tcatctttac
    18721 ggtcaagagt taaggagcgc tccgctaagc gtgtctcgag ttgtttaagc tcttgtcttt
    18781 cagacttaaa ttcttgttca atctcttcac gatattttct tgcctcttct tttgcttcta
    18841 aaagtaattc tttacgattt gctttacttt cacgtttagc tgtttttttg atgtgttcag
    18901 catctacttc tgctttgcca cgaatatcaa cagcttcttg ttcagcgttt aaaagagtca
    18961 actctgcagc ttccttcgca gacttgagtc taatcgaaat aagtgcataa cctaatatta
    19021 aaccaatgag ggcagaaaca attaataaaa taatattaac catgtttgta cctcaatata
    19081 ttctagattt cattaataga aagccatctc ttagtttatc ataaattgag cgtttacaca
    19141 attccaattc atttttaaaa aaattaacat ttgggccaag tggttgagaa ccctacttaa
    19201 aaaaagactg tagcaagtcg tccatgatgt aggcttctat ttcagaataa ctttttttcc
    19261 ggaggcgtgt taagacaaca cgccaagaaa tgggacgttc cattggaata cacttaatgt
    19321 cctttaattg gtataattct gtaataggtt tgggacaaat agttaagacg ttgtgattaa
    19381 tcttggtaga attaagcata aaatcccagg aagaggacgt caaaataata ttaggtctga
    19441 cttggtgacg ctcgcaagct tcaagcacta aatggtgaac cgtgaaacta ggatcaaata
    19501 gggcaagttg ttcatctgtt aaatcttccc actgaataac ttttttggaa gctaaacgat
    19561 ggcgtggaga caggcataca gataattctg atctctggat ttcataagtc tcaaccaaat
    19621 tatcagcgat gcctgttggg gataacaaga ctgcgacgtc aacatttccc acgagtagtt
    19681 cattttttag ttggtaagca ccaatctcct taacattgaa ttgaatcccc ggattttcta
    19741 aaatcagttt tggcattact tctgagaaaa caactgataa aataagagga ggaataccaa
    19801 tattgatact tccctttaac cctttactgt gatcatgcaa tttcaaaaac atgtcatcat
    19861 agagactgag aaccttttga gcgtccttat aataattatc accaagatag gttaacccaa
    19921 taatacgacc tctttttcgt ttgaagagct taacattttc tcttttttca aaatcattga
    19981 tcatcatgct aagtgtcggc tgcgacacat acaacagttc cgccgcctgg ctcaagttaa
    20041 aatgattttc aacgattgcg ataaaataac gaatttgttt aatatccaaa taggattctc
    20101 cttgtcttat caattgcttt ttccggtata attacctata ttatgacaca agtagatgtt
    20161 aaatgctatt gccaactcta tcaaaaaaat ttatatgctt ataaaaattc tatattttta
    20221 tttttagcgt tttcttgtta tcttagagac atggaaagcg cttttctaaa actgaaagga
    20281 tgtttatttt atgaaaaaca tagttatcgt tgaagcttta cgaactccta tcggagcttt
    20341 tggaggctcc tttaaaagtg tctctgctgt tgaacttgga acaactgtac tgaaaaaaat
    20401 ccttgataaa acgcaagtaa agcctgaaat ggttgatgaa gtcatcctag gaaacgtcct
    20461 tcatgcaggc ctaggacaaa atgtggcaag acaagttgca gtccactcag gaattcctga
    20521 agataaaaca gctttcacat tagatatggt ttgcggttct ggacttaaag caatccaatt
    20581 agctgcgcaa agcatcatgc ttggtgacgc tgatatcgtt attgctggtg gtgtcgaaaa
    20641 catgtcacaa gcaacctatg tatcaactca gcaccgtttt ggacagcgac ttggtaatag
    20701 tcaattgatt gatactcttg ttcatgatgg cttaacagat gcttttaaca attaccacat
    20761 gggtattact gctgaaaacg ttgctcagaa atatggcatc tcaagagaag agcaagatca
    20821 atttgcttta gaaagccaag aaaaagctgc taaagcatta gaaaatcatc gttttgctga
    20881 cgaaattgtc cctgtctctg tgcctcaacg acgcaaagac cctttaattg ttacaacaga
    20941 tgaataccca aaagttgata caagccttga aaaattacag caattacgtc ctgctttcct
    21001 ccctaaagaa ggaaccgtta ctgctgggaa tgcctcagga ataaacgatg gtgcagcctt
    21061 attgatgtta atgactgaag aaaaagctct tgaattaggg ttaacacctt tagtcactat
    21121 tgaaagctat gctagtgcag gtgttgcacc tgaactgatg ggaactggac caattcctgc
    21181 cactcaaaaa gcccttaaga aagctggatt aacaatttct gatttggact tagtggagtc
    21241 caatgaagca tttgcagcac agtccttggc ggttttaaaa gatttaaagt taaacccaga
    21301 aatcgtgaat gttaatggag gagccatcgc tttaggtcat cctattggtg ccagtggcgc
    21361 tcgcattcta gtcacattaa tccacgaaat gaaaaaacgc caagtaacca gaggactagc
    21421 aacactttgc attggtggag gacaaggaac tgctgttatc gtgaaaaaca atacttagtc
    21481 tcgtgaaagt tggtagaaaa aatgtgtaaa gaaatcacaa taaaagaagc ggtagctcac
    21541 gttaaagatg gtgataccat tatggttggt ggcttcatga caaatggcac accagaaaaa
    21601 ttaattgatg cacttgtgga aaaaggtgtc aaagacctca ctttaatctg taacgatgcc
    21661 ggttttcctg acaaaggcgt tggtaagatg gttgccaata aacagttttc aactattatt
    21721 gcatcacata tcggtctcaa ccgtgaagca ggccgacaaa tgactgaggg cgagactgta
    21781 attgatcttg tacctcaggg aacattagct gagcgcatcc gcagtggcgg ttttgggcta
    21841 ggcggtttct taacacctac tggaatagga accgaagttg ccaaaggaaa agaagtcatt
    21901 actattgacg gcaaagacta ccttcttgaa aaacctttga aagctgatgt cgcacttatt
    21961 tttgctaaca aggcagataa aaatggcaat ttgcaatacg caggttctga aaataacttt
    22021 aatcatgtga tggctgctaa tgcgaaaacc accattgttg aagcaagaga aattgttgac
    22081 gtggggcaaa tggatcctaa ttttgtccat actcctggca tttttgttaa ctacttagtg
    22141 aaaggagcct aacacgggaa catcaactac tgttctttca aaagaagaga ttcaaacacg
    22201 tattgctaag cgcgttgcac aagaattaga acacaataca ctggtcaact taggcatagg
    22261 tttgccaaca aaagtagcca actatattcc tgaaggtgta accattaccc tgcagtccga
    22321 aaatggtttt gtcggtctca ctggattaac agatgatcac tacgatccta ctattgttaa
    22381 tgctggtggg caacctgtta gtattgctcc tggaggggct ttcttcgata gctcaacttc
    22441 ctttggtatt attcgaggcg gccatgtggc cgcaaccgtc ttaggtgcct tacaagttga
    22501 taaagaagct agcattgcta attacctgat tcctggaaaa atggttcctg ggatgggagg
    22561 ggccatggac ttattggtag gtgctaaaaa agtcattgtt gcaatggagc ataccaataa
    22621 aggcaaagca aaaattttag acaaatgcac ccttcctctg actgctcaaa atgttgttaa
    22681 cctaatcatt actgaaatgg gagtctttga atatcaagat gaaggtctat gcgcccttga
    22741 aattaaccca gattacacct ttgaagacgt gcaaaacgtt accgaagtta ccctaattga
    22801 taaaacaaac taaagactaa ccaaaagaaa gacgaggata gtatcatgac acatactaaa
    22861 gaagttgcat ttatcactgg tgctgcaagc ggaattggaa aacaaatcgg ggaaacctta
    22921 ttaaaagaag gtaaaacggt tgttttttcc gacattaatc aagaaaaact ggatcaggtt
    22981 gttgctgact atactaaaga aggctatgac gcttttagtg ttgtgtgcga tgtcaccaaa
    23041 gaagaagcca tcaatgctgc tattgatacg gttgttgaaa aatatggtcg tattgatatt
    23101 ttggttaaca acgcaggtct tcaacatgtt gccatgattg aagattttcc aactgaaaaa
    23161 tttgaattca tgattaaaat catgttgaca gcaccattta ttgccattaa acgtgctttt
    23221 cctacaatga aagctcaaaa acacggtcgt attattaata tggcttctat caatggtgtc
    23281 attggttttg ctggcaaatc cgcctacaat tcagctaagc acggcttgat cggtctgacc
    23341 aaagtaactg ccttagaagc tgctgattca ggcattacgg tcaatgccat ttgtcctgga
    23401 tatgttgaca caccactggt tcgtggccag tttgaagacc tttccaaaac aagaggtatt
    23461 ccccttgaaa atgttcttga agaagtgcta tacccacttg ttcctcaaaa acgcctcatt
    23521 gacgttcaag aaattgcaga ctatgtgtct ttccttgcca gtgataaggc aaaaggtgtt
    23581 acaggtcaag cctgtatctt agacggtggc tacactgctc aataaatttg gagagataaa
    23641 gaggctgtat cttgtgatct gtctctttat tttctaataa ggaggtcata aaactatgga
    23701 aattattggt tctctggggg tcttggtagg tgttattgtt attatttacc tgtatgtcaa
    23761 agaagttaac attatcatcg ctgcgcctct tgctaccagc ttggtcattt tgtttaatca
    23821 aatggatcca accacaacct tacttggaaa agaacccaac caatttatgg gggcactctc
    23881 cacttatatt ctcaattatt ttgctatctt tttattaggt tctatcttag ccaaattaat
    23941 ggaaacaagc ggtgcaacca cttctattgc agattatatt ttaaaaaaag ttggtcatga
    24001 tagtccttat aaagtactcg ttgctatttt tctgatcagt gctatattaa cttatggggg
    24061 aatcagcctc tttgttgtca tgtttgctgt cttgccgctt gcacgaagcc tattcaaaaa
    24121 aatggacttg gcttggaact taattcaagt tcctctttgg ctcggtattg caacttttac
    24181 catgacgatt ttacccggaa cacctgccat tcaaaatgtt attcctattc aatacttgga
    24241 cacctcacta actgctgccg ccattccgag tatcgttggc tcaattggct gcgtggcttt
    24301 tgggctcttt tatatgaaat attgtctagc aaaaagtatg gcaaggggtg aaacttatgc
    24361 cacttatgct tttgacaatg agatacaagt gaaaacaaaa aatctcccac atttccttgc
    24421 cagtatctta cctttattgt tgctcattat tatcgcccta accggtagcc ttttcggaaa
    24481 cgattttttt aagaagaaca ttattttcat agcactttta gctgtcattc tcaccgcaag
    24541 ctggctcttt agacagttta ttcctaataa gattgctgtc tttaatttag gagctagcag
    24601 ctctattgca cctatttttg cgacagcatc tgcagttgcc ttcggagccg ttgtgatgat
    24661 tgtcccaggt ttcacattct tctcagatct cattttgaat attcccggta atcctcttat
    24721 tagtttagcc gtgttgactt cctctatgtc agctattacc ggctcttctt ccggtgctct
    24781 aggaattgtc atgcctaact ttgcccagta ttatttagat caaggcctta atcccgaaat
    24841 gattcaccgt gttgccacta ttgcttctaa tatctttacc attgtgcccc aaagtggtgt
    24901 ctttctcacc ttcttagcat tgacaggact taaccacaaa aatgctttta aagaaacctt
    24961 tattactgtt tctgtaagta cttttatcgc acaggtcatt gtgatagcct ttgatctgtt
    25021 ttcttagcct tttctcctcc acaagtagcc actttctcac tatttgtgtt atgataaagt
    25081 gtaaaacaaa ggagattgaa atgacaaaag aagttatcgt cgaaagtttt gagctagatc
    25141 atactattgt aaaggcccct tatgttcgtc ttatttctga agaatttgga cccaagggcg
    25201 atcgtattac aaattttgat gttcgcctag tgcagcctaa ccaaaattct attgaaacag
    25261 ccggtttgca taccattgaa cacttacttg ccaagctcat ccgccaacgc attgatggga
    25321 tgattgattg ctctcctttt ggctgtcgaa caggttttca ccttatcatg tggggaaaac
    25381 acagttctac tgatattgcc aaggtgatta aatccagcct agaagaaatt gcaactggga
    25441 ttacttggga agatgttcct ggaacaactc ttgaatcctg tgggaactat aaggatcata
    25501 gcctctttgc cgccaaagaa tgggctcaat tgattattga tcaagggatt tcagacgatc
    25561 cttttagtcg ccatgtcatc tgatactagt gtgttgtcaa acataacaat cctactgacc
    25621 tatttgactt gttacaaaaa acaagtctat ctgcagattt taagacaaca tactttatta
    25681 atcaaaaaac tgagacaagt tgccttatct cagttttttt gattttctca gtaatctaaa
    25741 gcatcagcat aacctttgcc atttcctaca aaataacccg tcttacaatt aatagagaac
    25801 agataagtgc catcaggctt aaacatatta tagtaaccat tgccattaat aatattaacc
    25861 ggctctaaaa tatattggtt gcctgaaata taacctctag cttgtgaggt tgctacaatt
    25921 ttttcaagaa ctcctggatt aaatgcccaa gatgggttag ctctgtcagc aataacatct
    25981 tgattgtaag gtacacgtga taaatgccgt tgtaagcttg caggatcata acttgtcaag
    26041 ccatagccag atggtgctac tgatgtactt tgtccttgag ctgcttgatc ctggactgct
    26101 tgctcattag ctgctttagc ggcctcagcc ttgctggcta gttgctgacg accttctgtg
    26161 atgcttgcct gcaagacagc atcaagattt gcatttcctg ttgtcaaggt tgcacttgat
    26221 aaatcatcaa aattagcatc agccttgact tcagccgaaa ccttttcacc atctacaaca
    26281 acatcggaaa caaatttacc gttaaccgct gtaatagcag caatagcttt cttaagggaa
    26341 tcgacttttg ctttcgcctt atcatagtaa gcagagcctt ccaaagcttt caaggcagct
    26401 tctaaatctg gcaaagtagc aaaggcacta ttttttaatt tgctctttgt ggcatctgta
    26461 taaaaagtac catatagttt ttcgaaagct ttagcagcag ccttcaagcg cgttgctttt
    26521 ttagcactgt cggtctgcaa agaggtcttt gtctgtttac ttgctgtttg agttgtttta
    26581 ccactgtctt gtctcaagaa atggttccaa ccaaatacaa ctgcaagaat ggccaataat
    26641 agcagaaata aagctattaa ccaacctttt ttcgtgtttt gtttggctgg atggtggcta
    26701 tcttcagaaa gaaactgatc tctttttggt tcttccttgg tcatctgtgg ttctggaatg
    26761 accctctctg atggatctag atctaacaca gggactgtcg cttccaccgg aatcccagtt
    26821 accaccgcag tagtctccat tggagctaag tcttcagcta cttcttcaac caaagtgcta
    26881 tcttgctcag cagactccgc agacacaggt tcgtcatcaa caagaccggc tttactcaat
    26941 gcttctcttt gttttttgat aaagttatct aaactagctg tatcaagctc tgtatactta
    27001 gcatcaaact tttgagaaga aacttcgtca cggtgttgct taatgtactt atctaaaata
    27061 ctatcatcct tagtaacacc tgcttttatc tctgactgtt tgcgtacagc ttcaccaatt
    27121 gtcattgact tggcttcatt aagccccaat gtttgcgatt cttttgttac ttcgacttct
    27181 ttgctttctt ctgacacgct tactacctct ctatatcaga tgtcgcttta ccctttcccc
    27241 ataaaattgg tacaaatcaa cttttagggt gccgttataa agtttacgtt ttttatcagc
    27301 tttttgcccg tattttagtt caaaaagttc atcacttgta aggataaatt tgctccatgt
    27361 tttcaatggt gcaaaggttt gtcccatttc attatacaag atgtcaaccg ctttgtcatc
    27421 aagcaaccgt tctccataag gaggatttga tatcactaca ccattaacct tgtctgttcg
    27481 aaagtcttgc agacgcattt gcttaaaggt aatcacatca gataaaccag cttcttcagc
    27541 attactttta gcaatctcaa tcatgcggcc atcgatatca aagccagaaa tatctaattc
    27601 gatttcataa ttagcttctt gttcagcatc atcacgaact tgttgcacca tatctttatc
    27661 tacccagctc cattcttcaa aagcaaacga acggttaaat cctggagcaa tattcatccc
    27721 aatcatggct gcctcgatgc aaaacgttcc cgatccacag gtgggatcaa ccagaggttt
    27781 atctggaaac cagttagata aggccaagat agcagctgcc atattttcct tgatcggtgc
    27841 tccacctttt tgaacgcgat accctcgttt aaataggcta gatcctgtcg tgtcaatcat
    27901 aatagtggct tggtctttta aaatagatac ctcaatgtta aacgttgacc caacttcttg
    27961 aagaggaact ccttctggcc tgtggaaatg cttttgcagt ttcttaacaa cggccttttt
    28021 ggtaatcgcc tgaacacttg gctcgttatg caatttagac ttaacacatt tggcttttga
    28081 gattggaaat ttagctccta gcggtaaata attttcccaa tccaaggcaa agacaccttg
    28141 gaataattct tcaaaggttc tagcaggaaa ttgtcctacg ataattttga tacgatctgc
    28201 tgcacgtaac caaagatttg ttttaacaat cgcttctaca tcaccttcaa aataaacttt
    28261 cccattttca acctgacaat caaagcctag tgctctgact tctttaccaa cgacagcttc
    28321 taaacctgcg gctgcagttg cgactaatct aaatgtttct ttcatatatc tctttctttt
    28381 aaatcaaata aaagctagca aatgctagct taacctatta tgcaattttc tataagccat
    28441 gttttgttcc ggaaataact aggaattatt tccttcgata atcatctgtc taccgtctgt
    28501 tgacagtcag gatagcttgt tcgtttccaa ctatcccatg cccctaccaa agtttgggtt
    28561 gctagcttga ggggtttacc gcgttccatt ttttacgttt ccataaaaac tacgtcactg
    28621 tggcactttc agaagtactt tggcatatca aacgacttag ccatttcctt cgccgtaatg
    28681 tgtatgcaca tccctaggct tatgtgttcg cctagcacaa tcactactgg catcacagcc
    28741 agtgctagca tggactttcc tcatagtatt aaaatactac gcgattatcc aaaaattgca
    28801 cagttttcat tactcaataa tttgtttacc aaaaacctct ttttccaatt tactaatacg
    28861 tttcaagatg tcaaaattag tagctgattg agcaacacga gtcggttgcg gtactggttg
    28921 ttgaacagtc gctgaaactg tatttctagc ttgaaacttc gcctttttta aggcttcatt
    28981 ctcagctttt aaagcttcaa tttgagcatt gaaattttca taatctttaa ttacattatc
    29041 aagaaattca tcaacttctt tcttatcaaa ccctcgcata ctagtcttaa attcttgctc
    29101 aaaaatatct ttaggactat aaataatact tgtcattctt tactctccga acggtcaatc
    29161 tttttaccaa aattatattt cagtattatt atcaatgata cagaaaaata gttcaaaaag
    29221 caagtattta aataccaata cccctaaaaa tacaatgcta gctttgtgac atatcattta
    29281 gccgatcaaa ggttagcaat agcaactgat aatgcggcat atcttttgct ttcttgagaa
    29341 aatattttaa gttggtctcg ttttctgtgt cataaaaaac ataagcccct tctgtctttt
    29401 ctaataaaaa ctgataatat tgactaaatt gcgtcggttg ttcgtaattt ggaaagtaat
    29461 attttacaaa gtcaacagcc ctaaactgac ttaaaacttc tttatttttt tcattccacc
    29521 tatctccatg cgtttcaaac aagaatatag tagctatctg caagggatac tcctctttta
    29581 gctcattagc tacttccaaa gcccattgtt caaaacccaa gttccctgta aagataaacc
    29641 aatccacacc attttccaaa taacctatta aatctttacg aatagcctgt ttaataattg
    29701 aaactcgtgg gtctttatgg tcaaaaatcc ctatttcaaa gcttcggtaa cctgtaatta
    29761 gaatcgcagt cattaggtgt tatcctttca aaaaatatgt tataataaaa gtgcttaaat
    29821 ttttagcatt aactagataa tattaggaga acaatggtta attatcctca taatcttatt
    29881 cgacaaaaag taagttccgt tcaaaagcaa aataaggtgg acttcgccaa tagaggtatg
    29941 tcctttgaag ctgctatcaa cgcgacaaat gattattatt tatctcgtca aatagctgtc
    30001 attcacaaaa aacctactcc tgtccaaatt gtcaaagtgg attaccctaa acgcagtcgg
    30061 gcaaaaatcg ttgaagcgta ctttagacaa gcttcaacga ctgactattg cggcgtttat
    30121 aaaggacatt atgttgattt tgaagcaaaa gaaaccaggc aaaaaacagc tatgcccatg
    30181 aaaaatttcc atttacatca gattgaacat atggcttgcg ttttacatca aaaaggaatc
    30241 tgctttgtcc ttcttcactt ttccacactg aaggagactt actacctacc tgctcaagcc
    30301 ttgatttcat tttatcagat agataatggc agtaaatcga tgcccattga ttatatcaga
    30361 aaaaatggct ttaaggtagc atttggagcc tttccacaag tcccttattt aaacataatt
    30421 gaacaaaatt ttttaggcgg tgattacaat taaaaatcca aaaatcctta agtggctaaa
    30481 gtatgtatta agtgcaattc ttagccttat tatccttgtt attattattg gtggtctttt
    30541 gtttaccttc tacattagca gtgctccgaa actgtcagaa gcccagttaa aatcaacaaa
    30601 ctctagcttg gtttatgacg gtaataacaa tctgattgct gatttgggtt ctgaaaagcg
    30661 tgaaaatgta acagctgata gtatccctat taatctagtt aatgctatta cctcaattga
    30721 agataaacgt ttctttaacc atcgtggagt agatctttat cgtatttttg gtgctgcctt
    30781 tcataatcta acgagtcaga ccactcaagg ggggtcaacg cttgatcagc aactcattaa
    30841 actagcctat ttttctacta atgaatctga tcaaacctta aaacgtaagg ctcaagaagt
    30901 ttggcttgct cttcaaatgg agcgaaaata tactaaacaa gaaatcctga ctttttacat
    30961 caacaaagta tatatgggta atggcaacta tggtatgctg acagccgcta agtcttatta
    31021 tggcaaggat cttaaggatt tatcttatgc ccaactagcc ctattggctg gaatccctca
    31081 agctcctagt caatatgatc cttaccttca tcctgaagct gctcaaaatc gccgtaacgt
    31141 cgtgttgcaa cagatgtaca tggaaaaaca tctgacgaaa gcagaatatg aaactgccat
    31201 cgcaactccc gtcgctgaag gtctacaatc actccaacag cgctcaactt atccaaaata
    31261 tatggataat tatctaaaac aagttattga agaagtcaaa aaagaaacga ataaagatat
    31321 ttttaccgct ggtttaaaag tttataccaa tattatcccc gatgcgcagc agactcttta
    31381 taatatttat cattctggtg attatgttta ctatccagac caagatttcc aagttgcttc
    31441 aacgattgtt gatgtgacaa atggtcatgt tattgctcag cttggcggac gtaatcaaga
    31501 tgaaaatgtt tcatttggga ctaaccaagc tgttttaact gatcgtgact ggggttctac
    31561 catgaagcca atcacagcct atgctcctgc tattgaatct ggtgtttata cttctactgc
    31621 tcagtcgact aatgactcag tctattattg gcctggaacc actacccaat tgtttaactg
    31681 ggaccttaga tataacggat ggatgacaat ccaagctgct attatgctat cgcgaaatgt
    31741 cccagcagtc cgagcactgg aagccgcagg acttgactat gctcgatctt tcttaagcag
    31801 tttaggtatt aactatcccg aaatgcacta ctcaaacgct atctcaagta ataacagtag
    31861 ctcagataaa aaatatggtg caagtagtga aaaaatggcc gctgcatacg ctgcttttgc
    31921 aaatggtggt atttatcata aaccaaggta tgtcaataaa gtggaattta gtgatggtac
    31981 aagtaaaact tttgatgaaa aaggaaaacg tgccatgaaa gaaaccacgg cctatatgat
    32041 gacagatatg ttaaaaactg ttctcactta tggtacaggt actgctgctg ccattcctgg
    32101 tgttgcgcaa gctggtaaaa cagggacttc taactacact gatgaggaac tagctaaaat
    32161 tggtgaaaaa tacggccttt atccagatta tgttggtaca ttagcgccag acgaaaactt
    32221 tgttggcttt actaagcgct acgccatggc tgtttggaca ggttacaaaa accgcttgac
    32281 cccagtatac ggatcaagtc tagagattgc atctgacgtt tatcgtagca tgatgactta
    32341 cttaacaaat ggttacagtg aagattggac gatgccaaat ggtctttatc gcagtggtgg
    32401 attcctctac ttaagcggaa cctatgcgag caacaccgac tatactaatt cggtttacaa
    32461 caatctttac agcaataaca cgacaacagc ttctagccaa acgacttcag atgatactag
    32521 tagtagcaat gatacaagta attcaaccaa tacagacaac aatggcagtc atccatctac
    32581 cgatgataaa aagacaactc attaatctct aacctctact tattgtctgt acctaccttt
    32641 tattacatat ccatttagtt acttttaata tctaccttaa gtgataatct aaataaaaag
    32701 cgagtccacg ttctgtgagg actcgctttt tatatgacac aaatgactta ccacatacaa
    32761 tataaaacaa aaaacagaat tctttaatcg tattaaagaa aaggtacaac gttaagggaa
    32821 ttagcaactg atttttcaaa cgttaaccta aaacaaaata gacttattta aaattgttat
    32881 aaatagcaac taatgccata agagagtata catgaaaaaa acacgtttcc atataccgaa
    32941 gacgtgtttt ttcatatgtc attttcttag cataataatt tttttcatgt tcactttctt
    33001 atgcggagtc caatccgttt gctgttcgtt ttgtccagct tttagatttc atacagtcgc
    33061 aaagaaagga attagtattg tgctaaagca cccattggat cccaaggagc tagtacttgt
    33121 ggctcttttt cataagccgc taactcgtca gctgttaaga attctttacg gacaacaatt
    33181 tgataggtat attcatccat ccaagcatct gaagcaacaa agtaaccttt gtcaccaacc
    33241 ttctcacccc atgaattttc aaccttccat tttaacggtt ttcctgtttc atctaagtca
    33301 acacctgtta aaaccatagc atgtgtcatc aaactttcac tataatccaa acgtccagcc
    33361 ttatcttgac taagattgat atccatacta gcttcaaaat cgtaagtatt agttgctaaa
    33421 atgccttttt gacgatctga aacttgaccc acatcagagc caaaccaaac ggactcacca
    33481 gcctgcatct gcttgatagc tagttctttg aaacgtttca tatcaaggtt gaggtagcga
    33541 acctcacgac taccgaccac atttcctagc atctcaacag tgtatgattt gccataaggc
    33601 ttatcagcag ttggcgcatt aataacagac acataatcag aaagctttaa gccaacaaat
    33661 ttgtcgtaaa acgcttgcgg tgtcaaacct ttctcaacat gatagtggtc atctttatca
    33721 cggtaggcaa aatcaaaatg acgaggtggt aaaccaaggg tcatggccaa gaagttaaaa
    33781 atttcctgaa gaagctctgc ttttcgatcc tcaacttggt ctgccttagc acctgacgca
    33841 atcaggtcac gaagaatttg agcatcttgg cgcaataatt tattcaaata ctggtttaat
    33901 tcacgactgt tacttgatga gattgattct gggtaaacag attttggcac cactccatac
    33961 ttctcaaaca aggaaaccac catgtcccac tgaccaccat cttgttgtgg aacatccaag
    34021 agaaacttaa ctttacgact ggttaattct tggtcagctg tagcaatgac ctgctccata
    34081 aaccagttag ctttttcata cttatcccaa aagaaagtat gagcttgtga cagttcaaaa
    34141 ttttctaact taaattctgt gattaatttg tgtcggaaag tgttcaaggc agcaaacatc
    34201 cagcaacgac cagaagcctt ttggttagat accttatctt tagttaaatc aatagaaaac
    34261 acaaaatcat tgtccacttc actttgacgg gtttctaatg attttagcaa accattatgc
    34321 gtaacggcat tctcaatagc tgaaaatttt gcattggctt cgtaatgagc aaataattgt
    34381 tctgtaaatg tctctgttaa tgctgacatt attgtcctcc taaaatatta agataagctt
    34441 cacctgaaat aatattggca agatggttat tatccagcca ttctattcta aaggattact
    34501 tctattatag accttatttg attttcttca agaaaaaagt taggataacc taactttttt
    34561 tgttttcttt ttttactctt tgaacatcat ctcttatttc caaaaatcat caaaaatggt
    34621 gattggcagg tgacgcttgt gttgtccttt atgccaccat ttttcaatag ttgcttgagc
    34681 tactttggaa atcagcttcc cttccaaata gtcgtcgatg tcttgatagg tcacccctag
    34741 agcaacctca tcagccaagc ctggtttttg atcttctaaa tcagcagttg gaactttttc
    34801 atacaaagca gcatctgctc ctaaaacttt caaaagagcc tttccttgac gtttgttaag
    34861 cctaaagagg ggaagaatat ctgctccacc atcaccaaat ttagtaaaga aaccagtgat
    34921 gttttctgcc gcatgatccg ttccaataac agcaccagcc atttggccag caatggcata
    34981 ttgactgatc attcgctgac gtgctttaat attaccttta ttgaaatcag aaatctcaac
    35041 gcctgctgct tgtagagcct ctacttgacc gtccacagct gccttgatat taatggtaag
    35101 ggtctgatct ggtgcaataa aagccaaggc tttttgcgca tctgcttcat cagcctgaac
    35161 cccataaggc aagcgaacag ctataaattg gtaagcttga tcacttgctt cctcccgtaa
    35221 ctctgcaatg gccatttggg ctagctttcc tgcgagggta gaatcctgac ctcccgaaat
    35281 gcctaagaca taagttttta aaaatgagtg cttacgcaaa taagctttta aaaaatcaac
    35341 ggctttccga atttcttctt gtgggtcaat gctagccttg acgcctaatt gtcgaattat
    35401 ctcttcttgt agtgtcatgt cattcactct ttccataagc atctttgcga atgttatcaa
    35461 ttaaggccat cttgttttgc cacacatcac gggctaagtc tactgggtag tcttgaggat
    35521 ttaagacacg cttgtattca tcccaaagct tgtcaaattc ttttttagca taagccttga
    35581 tttcagctaa ggtcggtagc tggtaaacta attctccctt gacaaaaata tcaactaaga
    35641 gaggaattgc atcaaattct ttaacggttt tcttaatata ggtataggtc ggatggaaca
    35701 tctcaatctc agttaattca ttaacattaa tatcagtaaa cgtgatatag tcgccttctg
    35761 atttgccttt ttcacgactg gtgatgcgcc aaacttgttt tttacctggt gtggatactt
    35821 tttctgcatt atttgataat ttgatcgtat cacgcatgct gccatcttct tgctcaatag
    35881 agacaatctt ataaacagca cctaaggcag gctgatcata ggctgtgatc agtttggtcc
    35941 caacacccca aacatcaatt ttggcctttt gcatttttaa gttgaggatg gtattttcat
    36001 cgaggtcatt agaagcatag atcttagcct cggtaaaacc agcgtcgtct aactgctgac
    36061 ggactgtttt tgagaggtaa gccaagtcac cagagtccaa tcgaacacct agaaaattaa
    36121 tcttgtcacc catttctttg gctactcgga tagctgttgg cacacctact ttaagtgtat
    36181 cataggtgtc aacaagaaat acacaatctt tatgggtctt agcataagcc atgaaagcat
    36241 cataatcatt accataggct tgcactaaag catgagcatg cgtacctgaa acagggatat
    36301 caaagcgttt acctgctctc acattacttg ttgcatctgc tccaccaatc atcgctgcgc
    36361 gggttcccca aatcgcagca tctagttcct gtgcacgacg ggtgccaaat tccaaaaggg
    36421 gttcatcctc aatcacagaa cgaatacgag cagcctttgt agcaatcaag gtctggaagt
    36481 taacaatgtt taaaagagct gtttcgacca actgacactg acctagaggg ccttctactt
    36541 gcacaatcgg ctcattagca aaaaccaaat ctccttcttt agctgaacgg atggtcaatt
    36601 ctaatcgtaa ctctttaagg taggtcaaaa agttttctgg ataacccagt tcttcaaggt
    36661 aagccaaatc tgtttctgaa aattgaaatt gctctaggta ctccaccatg cgctgtaaac
    36721 cggcaaaaac agcataacca ttgttaaaag gttccttgcg gaaatagact tcaaacaccg
    36781 catgacgatt atgaatgccc tgctcaaaat aaacttgcat catattaatc tgatacaaat
    36841 cagtatggag agttaaacta tcatctttat acataaaggg gactcctttg aattattgtt
    36901 actattataa catattttaa aaaagactct ttggctaggg tttagaaata acttgagtta
    36961 tcgctaaagt aaaaaaagaa ctgatccatc atgacatcct caaataagaa agagttaatg
    37021 gattcagttc tatatcgcta attattattt aaatttgaca ttgctataaa tcccaaaaac
    37081 aataatccaa atcgttgctc caatggcgcc gatataggtg gattcttgta agaaaagaga
    37141 gataaagaca aaggcaaaga aagcaagggt caaaggcgtt gtcactttat attttggcat
    37201 caaataacca tctgccataa agtccttaga ttgacggtac ttccagtgag caatcatggt
    37261 taaggcgtag atagcaatat atacacctga tgaggaggcc gtaatgagtg agaacgcatc
    37321 tgcaactcct ggtaggatat taatcaaagc tgagatacca accacaaccg ctgaagcaat
    37381 aatggcacga cttggcaccc cttgtcgaga taaagtatta atctttaagc gattggtcaa
    37441 agcgtttgga gtctcattag caatctgata gagatgacga ccggttgaat aaagggttga
    37501 gttaagcgct gacgctgctg atgtcaagac cacaaagtta atcaaggctg ctgcccattt
    37561 aataccaatc aatttgaaca ccatcacaaa aggagattca tcaactggta actgatgcca
    37621 tggcacaatt gccataatag agaccaaggc tcccacataa aagatcacaa tacgggttgg
    37681 aatttcttga atagcctttg gtagaacttt tcttgggtta gccgtctcag aagtggtaat
    37741 tcccacaaat tcgatagctt gataagcaaa gaaaaccatt tggaaggcca taaagaactt
    37801 tagtttccca tttgggaaca tggaaaaatg gtcaaaaata ttggaaaggc tagcatggcc
    37861 tgtgtgagtt tcaaaacctg tcaataccat gaaaatagct gttgcaatca aagctaaaat
    37921 agctaaaatc ttaatcatgg caaaccaaaa ctctgtttcc ccaaaaacgc gcacagcaat
    37981 taagttgatc gaactaagta agactaagaa aaccaactga atcaaccagg ctggccagct
    38041 tgggaaccaa aattgcacat aagcacctac tgctgtgatt tctgccattc caataaaaat
    38101 aagggaaatc caataggata gacccgaaaa ataaccccag cctggaccaa tgtatttgga
    38161 aataaaattg ataaaggtgt gttgatctgg atcataatag agcatttcac cgatggcacg
    38221 catcatcata aacatgaagg cacctgtaat catatacaca aaaataatag atggtcctgt
    38281 tagggcaata gagcgtcctg cccctaaaaa gagacctgtt ccaatcgttc ctgcgatcgc
    38341 aattaactgc acatgacgat tttctaagcc ccttaccatt ccattttcta gttcgttatt
    38401 gtctgtttgt tcttttatag acattctaaa ctccattcac taaaatacta tttattatat
    38461 ccttttttca gaaaattttc aacatttatc taggaaagat attaaggaaa actgttcttt
    38521 atatttctta aaggtcttat gcaatttagc ttttttaagg gtgagacaag gaaaaatgaa
    38581 ggagttttaa ccttatgaag agaaactttc aaggtagtga taaacacctt gccctgcaat
    38641 tgcaccatct ccaacagctg tcgtgatttg gcgaaggtct ttttgacgaa catctccaat
    38701 cgcaaaaata ccaggaatac ttgtcctcat atgatcatct gtgataatcc aaccttctga
    38761 atcggtaatt tctagatcct ttaccatacc tgtaacagga ttcataccaa catagataaa
    38821 cacacctcca aaagcgtggt cagtgacttg gcctgttttc acattttcga ttaggacatt
    38881 ggagacctta atgtcgttac cttgaatttc tttgacaact gaatcccaga taaagtcaac
    38941 tttgtcatta gcgaaggcac ggtcctgcaa gattttctga gctcttagtt gatcacggcg
    39001 atgaacaacg gttacctttt tagcaaactg agtaagataa atagcttctt caactgctga
    39061 gtcaccacca ccaacgacca aaagatcctg gtcacggaaa aacgcaccat cacatactgc
    39121 acaataagaa actcctcgac tagtatagta ttcttcacct ggaacaccta gtacacggta
    39181 tttagctccc gttgcaataa taaccgtttt agcttcataa ctagcatctt cagtcaacac
    39241 acacttatag tcaccaaaat tttctatttt ttgaacaata ccataaatgt tttcaacgtt
    39301 aaacttctct aaaggttcgt acattttcat agctaattct ggtccagata tatgatcata
    39361 tcccgggtaa ttctctatat caaaagtgtt gttcatctga ccaccaggtg ccccttgttc
    39421 aataatggca acagataaat tacttctagc agcgtataaa gcggcagtca ttcctgctgg
    39481 tcctgaacca ataattaatg tatcgtacat gatttttctc ctttaatcta ctcttgccaa
    39541 tattttagca atgataatcc cttcttgcaa tgattaggat tttatgacaa ccaaaatact
    39601 cataaaagca aacgataaaa ttgggatggt taaaatagca accattagca tctcataaag
    39661 aaaagcttgt ctttcaatca atgttttatc tcttttggtt tttgctcgcc ataaagtcca
    39721 tattaaacaa attaaaatca tagtaaggct tgagagaatg agacctttta cataaaggct
    39781 aaagatttct actaacatat ttccacctag tcattatttc tttcccataa gtttttctaa
    39841 aaaacataac aagaaaagcc cagggatacc tagacctttt tattataaca aaagaataac
    39901 attaaatgta tgtttttgaa tagcttgcaa aaaattcttt ggttcgttct ttttgaggat
    39961 gtctaaagac ttcttcaggt gttccttgtt ccaagatttt cccttgatct aaaaagagta
    40021 ctctatctgc cacttggtaa acaaaattca tgtcgtgact cactaaaacc atggtctgtc
    40081 cggatttagc agcatcagta atagactttt ccacttcgcc aactaattcc gggtcaagag
    40141 ccgaggtcgg ctcatctagt aataaaacat ctggtttcat agccagagct cttgctaaag
    40201 ctacccgttg tttttgtccc cctgataaat gacgtgggta atgatgtttt cgatctgcta
    40261 aaccaacctt agccaattct gcttgcgcca gtttagtcgc ttcttggtca gacagttttt
    40321 tgaccacctt aagaccttct ttgacattct caagggctgt acgacgctca aaaagattaa
    40381 attgttgaaa aaccatggca agtttccgac gtaaaataag gacttgctct gtggtaatgg
    40441 tctcaaaatc aaccgtaaag tcaccaatgc taatggagcc tgaatctggt ttttccaaat
    40501 agtttaggct acgaaggaag gtcgatttcc ctgctcctga agcaccaact aaagcaatca
    40561 cttgaccttt ttcaatatca agagccaaac tatctaaaac tttttgccct gagaatgtct
    40621 tgctcaaatt tctaattgta atcatcaacg caattctcct aacttttcat ttctagcttg
    40681 ttctggtgct ttgatggcca tcttgttttc aatcaagcga cctacttgct ccatcaaaat
    40741 actgatagac caatagacaa gagcaacaga gatataacgt tcaaaataac ggtaatctga
    40801 tccgcctaga atttgagcct gggcaaacat ttcgacaatc cctgcattaa aggcaagcga
    40861 tgttccttta gttaagccaa ttaacccatt aatcaaggtt ggaatagcca caacagttgc
    40921 attaggaata atgacacgac ggtaaacctg cacagaagtc atgcctagac tttttgctgc
    40981 ttcaatttca cctgtatcta ctgataaaat ggctgcccga atagtttcac tagcgtaggc
    41041 tgcttcatta aaagcaaagg ctgtaatggc aaaaatagaa gccggaattg cattaacatt
    41101 ccaatcaaag ccatacttct gattgagaaa ttttagaaag aggggaatac cgtagtaggt
    41161 caacatcaac tgtaccaaaa taggagttcc tcgcaagaaa ctcacaaaaa tagcttgaat
    41221 agggtatagt agcttcactt tattaatttt gacaagggca aaaatcaaag ccaaaaccaa
    41281 gccaaaggtt gctcctgata gtgtcaaacc aagcgtaatt ggaagccgtt ggataatatt
    41341 tggaatggca tcaaaaacag catgccaact aaaaagtttc ccatgtggaa tcggtgagat
    41401 gaggtaatca taaaaagccc aaccactggt taaaaacact gatgtcatgt atttcccctt
    41461 tgtatttgtt tgtcttaata ttctaacact cttagaccca catgtaaaat agtaaattcg
    41521 tattatagca ataagcaaaa gctatgatca ctttttgtgt taacaaatgg taaacaatac
    41581 aagtagcagg tgtaaaaaaa gcaagattag atgccaattg atcacttgct tgctctttgt
    41641 tcttaaaaat gttgtttttt ggccttacgc tcagcgcggc ccttagcacg attttcagca
    41701 cgacgttctt tgcgacgttt ttcatcaacc gcccactgaa tttttttctt gtaacctggt
    41761 ttgacttttt tctttttctt tttgaccaaa ccaatcattt ctgtgtctaa tttttgatag
    41821 gctttttcac ggttttgacg gcgatcacgg tcataggtat cttgaaattc tccatttttg
    41881 agcaccttcg gtgtaaaggc aatccccatt ttttccagct ctttgatatc tgagtcgtca
    41941 cttggctggt aaagtgtaat ggcagttcct gccataccat ttcgacctgt tcggcctaca
    42001 cgatggacaa agaaagacaa gtcttgtggg atggcgtcat tgatcacatg gctgacccct
    42061 tcaatgtcaa tcccacgcgc tgctaagtct gtggcaacaa tgtattcaaa gtccagtttt
    42121 ttgacttggt tcatgatgcg cttacgttct cttggaggaa tgcccccatg aatcttagcc
    42181 acttttaagc cattagctgt taaaaaggca tgcaaatcat ctgcgcgttc cttggtattg
    42241 acaaaaagca tagccatata aggctgcatg gttttgagaa tctctaacag ttgaccattc
    42301 ttatcacgcc cttttgtcga cacaagccag ttatcaatgg tatctgcgat aacggtcttt
    42361 gtcttgattt gttcaataac aggattggtc aagtattttt tcaaaaaggg ttgtaatttc
    42421 tgtggaatag ttgctgagaa caccaaaatc tgaacagatt ttggaagcga agctgcaatc
    42481 ttatctaccg tatccaaaaa gcccatgtcc atggtcatat cggcctcatc cacaacaaag
    42541 gtcgttgctt tatgaatcgc taaatcacca gacttgacca agtcataaat acgacctggg
    42601 gtcccgatga caatatgcgg ctggctgtct tttagttttt caatctgacg gagtttgtct
    42661 gtgcctccaa catagttggc caaacgaatc tcttcttgga agtgcttagc aatctgttta
    42721 caagcatcaa aaatttgagt tgctaattca cggctaggtg ctgtaataac gacttgcact
    42781 tctgctttag cttcatcaag tttttcaaaa atgggcaaca aaaaggtgtg ggttttccct
    42841 gaacctgttt ttgattcccc aactaagtca cgaccggagt taacaatagg aatcagccgc
    42901 ttctggacct ctgttggatt gacaaagcca atttcttcca gcgcttgctg aacgtattgc
    42961 ttaaaatgat aatctttaaa tgacatgttt tacctcgttt tcttccatat tatatcatta
    43021 ttgttagaga caagcaaaag gagtgggaca acactcgcaa aatcagcatt tgtgggtcat
    43081 ctccactctc ttattgatga tgttaatcaa aatgctattg gtgactattc ttgataatcc
    43141 cccttagaac acgtataaga tagctaaaac tagtaaacta gctagacttc ctactcccca
    43201 caaaaaagca tctacctgcc attctgacca cttcttgcct ttaccagaca agcctcccaa
    43261 ttccaaatgg tggtggaaag gcgtcattct aaaaatacga cgaccttctc catatttttt
    43321 cttggtgtac ttgaaatagg acacttgcaa catcacagaa cttgtttcaa gaacataaac
    43381 gatcccaata atcaggagag tccattcttg acgaagcgca atagaaatgg cagccaacat
    43441 agctccaagg gctaaactac ctacatctcc cataaatact ttagcaggtt tgtgattaaa
    43501 gcagaagaag ccaagcaagg ctccaatcat tgctccaatc agtaacaaaa catcaaattg
    43561 actctgaacg taggcaataa cgccgtaagt cactagacta atcaccactg agatagaagc
    43621 taagccatcg ataccatctg tcaaattaac ggcatttgaa aaaccaacca cccaaaacaa
    43681 aacaaagaat aggtagaaaa ttcccagcgg cagctgataa ccaaacacat taatagagga
    43741 aatgccactt ggactaacat gtaaaaaata gaacatcaat cctccaacca actgcaaggc
    43801 taacttttgt ttggctgtca atccttcatt gatttgctta aaaattttta aaaaatcatc
    43861 caaaaatccg ataatcccgt aaatgacaac aattgataaa atgcctgaaa tcaaagctaa
    43921 actttgagtg tttttgatcg aaaatagact aaccaataac gatactgccg tagctactaa
    43981 aagaaaaaca gttcccccca tagtcggtgt tccagcttta gctaaatgtt gcttgacatc
    44041 ttcatgcatt tgttgcccac caattttttt caattgatag aatttgataa aataaggcat
    44101 tgtgaaagca gataccataa aggatatgat tgctgcaata agggttaaaa acatgttaat
    44161 ctcctaaagt aatggtcatt ttttttattt ttttcaagga cttaccaaca tcaacacttt
    44221 gtttcataac acgaccagaa tctgttcctt taaagctgat gtctattcca gtccatttag
    44281 caaaggtttt aacattggat tttgtccagc catacatgtc tggtacctcc acaaaacggt
    44341 ctgataatat gagaacttgt tggttttctg ttaacgtttg accgggctga tgcgatactt
    44401 ttttgatctt gctgccagta ccaaggacaa ctggctggac aaggtttcga cgcaactcgc
    44461 ttgatgtctc accaggattc tttcctacaa agtttggtaa tttataagtt gtttgacgat
    44521 tagcatctga tactactggc ttagttagtg tatcttgcat taagtatgct tcttccaata
    44581 ctgggttaac cacatcttgc caaaaaaggg gaccaaaatg ttgtggttta gtcatagtaa
    44641 catacatcaa aaagtctggt ttatcagctg gcaccattgc cacaaccgaa tagacatagt
    44701 tagtcaatcc accatcttga taaccacttc catcttctga accaatttgt gctgttcctg
    44761 atttaacagc aacaggtaaa tcacccactt taataattgg tccaaatgtt tttgaataga
    44821 gtgttccaaa ctcagggtct gttcctacac caatcatgta ttgtcttgtt tcactagcgg
    44881 ctttttttga tacaggtttt ccaacaattt ctttatttgc cgttctaaaa cttgctgtgt
    44941 taggatcata aatttgactg ataaattgtg gctctaacat ctcaccatta ttagaaatag
    45001 cagtaaaggc tctaagcatt tgaatctggg ttacagaaat cccttgacca aaagcgctca
    45061 tagcttgagt cacgatatta tcagaaggaa atatacctgc gtcttcatct tttaaaccaa
    45121 aacgagtagg aaaaccaaag cggaacttcg tcaaataatt catccatttt gcattaccca
    45181 ttttttgttc aagtttagtc atcccaacgt tacttgagaa ggcaaaccct tgtgcataat
    45241 tcatgtactg tcctgtggaa atgccttcgt taatagacca gtcttgaata gtagcatctg
    45301 caattgtcaa accattagca ttgctaaagg tttcgtttgg gttgaaaact ttatcatcaa
    45361 tagccgctgc cagagtcatc actttcatgg ttgaacctgg ttcaaaattt ccttgatgaa
    45421 gtgcactgta ccatttgtag ttcgtatttt caagtccttt cagagtatca gcattataag
    45481 tggggcgttg tgttgttgcc aaaatttcac cagttttagc attaacaagt gttgcactgg
    45541 ccaactgacc atttgatttg gcttgaaaaa catccatctg ggtttctaag aaggtctgga
    45601 taggctcaga tagcgttgtg taaatatctt tgccatcaat agctttcttg acagtcttac
    45661 ctgtacccaa gagtgtggtc ccatttcgat ctttttgata agtaataaca ccatcttgac
    45721 ctgataaaat tttatcaaaa gaagcttcta gacctgtttt tccaactaaa ctcttaacac
    45781 ctgtcttttt atcttctgtt agagatgcta ggcctataaa ttctgaagca aatgtcccat
    45841 ttggatacat acgaccagga ctagttgtga aagcaattcc cttgattttg gcatcttcca
    45901 tagccttttg aatagtagac atagtactat atgaaatgcc agaccctgac ggtccaaacg
    45961 agacttggaa aagtccttta cgcttaagct gtttaattac atctgttttt ttcattccca
    46021 gatgcttttt taaaatatca gctactgttt catactgaga aggttgtaca tataactttt
    46081 catctgaagc cgagacaaat gatttatcca aaattgcgta tatgctataa gtcgtagaat
    46141 ccactgcaat agctgtacca tttcgatcat aaatggtccc acgcttagct tggatcgtaa
    46201 cggtttcttg ataaaccttc ttcgcccctt ctgacaaact aactccaaac ttttgatctg
    46261 ttccaataat aatcatgaaa ttaataatga aaataaagaa aataaagata gttaagagca
    46321 tcatattttg tccaactcga acgcgatttt cgactggagt tctcctatcg cgcacaacat
    46381 aatctaaaac atatttttgc cattttttca tagattactc gactttcttg atattattat
    46441 tacggttgct taagcctgct ttaccagcaa tatctataat acgatcacgg cgagataact
    46501 catttacttc ttgcttggca ttattaagct ctagtttttg atccgaaata tgactattta
    46561 aactagtgat ttcttgttgt agctgcaact tacgactttg caggtaaata atacttactg
    46621 ccatcgtaat cgctgttaca atgatagcag tataaaaagc cttctcaatt ctagagaaag
    46681 tttttattcg tttttgcaag gcatttgtaa ctgcctgagt tcttttttca tttgtcatag
    46741 gcttatttcc gaattttttt ggcaacacgt agcttggctg agtgtgccct tttattagct
    46801 gttaactctg aatgactagg taagatcggc ttacgtgaaa caagttcaaa cttaggtttc
    46861 atatcttcag gaattagagg aagccctttt ggcacatcca ccgtactagc ttctttaaac
    46921 aactgcttgg ttaggcgatc ttccagagaa tggaaggtaa taactgagat acgaccatca
    46981 agggctaata attccatagc gtcctgaata gattcatcgg ccgctcccaa ttcatcattg
    47041 acttcaatgc gaatagcttg aaaaatctgt ttagcagggt ggcctttttt cttcaactct
    47101 ttagctggct ttgctgcctt aatcaattct gccaactctg ttgttgtctc aataggctta
    47161 atagctcttg cttgttcaat ttttcgagcg atctgcttgg agaatttatc ttcaccatat
    47221 ttgaaaaaaa tcttaaccaa atcattgaat ggataggtat tcaccacttc gtaagctgtt
    47281 aagagcgact gacgatccat gcgcatatcc aatggagcat cttgtttata agaaaaccct
    47341 cgttctcttt catccaattg cgggctggaa acaccaaggt catataagat accatcaatt
    47401 tcatcaactc caagcgctgt taaacgtgct ttgaggtgtc taaaattatc tttaataaaa
    47461 gttacctgtc ctttgtcaat ataagatttg agggtaactt gtgcattgtc aatagccttt
    47521 tggtcttggt caaaacaata gaggtgccct tcttcaccaa gtttggacaa caaataagct
    47581 gagtggcctg agccacctag cgtcgcatca acataaatcc catcaggctt tatgtcaagc
    47641 atgtccactg tttcgtgaag gagtacggtc acgtgatgaa attcttttgt cataacttta
    47701 attgtaccat acttcaaaag gtttagaaat gaaaaagtaa gagaaaagga tttcattctc
    47761 gtgggaatct tcctcttctc taatcttgtt ctttttgttc gctatcagcc aacttagcaa
    47821 gcactgactt agccactgcc tctagagttt caactgcttg taaaagattt ttagcttcct
    47881 taatcacaca acaatctgtc agcgggttgt ctaaccaaat accaaaggtt ttatcccaaa
    47941 tcgtatttgg taagtcagct aataatagcc tatcgacgtc tgccagctat cttcggcagt
    48001 tttgaagagt aacttgtaag tctattaata attggttgac cttgctcatt atttcgacgt
    48061 ttgatccagc taaccagcat accatctcca aaaaaaacaa aatagcccca atttcggaca
    48121 attttcaatt ccaaatgaat cacctgaatc tgatgtaaaa gttcttctaa agtaaccttt
    48181 gcttcttctt tttctctttc attagtcatt aagggacctt atagtagctt attctctgat
    48241 atgtccatcc ccattaatat aaaatttagt gctggtcaag gcttctaagc ccattggccc
    48301 acgggcgtgc attttttgag tagaaatccc aatttcagca ccaagcccaa aaacaaaacc
    48361 atcggtaaat cgtgttgaag cgttgacata aacagcagca gcatccacta aatcttgaaa
    48421 ggtctctgct gccttaatat cccttgtgat gatagcttcg gaatggtgac tagtatactg
    48481 atttatccaa gaaatagctt cttccaaaga ggaaacaacc ttaacagaca tgatataatc
    48541 taaaaattcg gtctcaaaat cctctgcttt tgcaggcact gcctgctcaa ataacggcaa
    48601 agccttgtca tctgcccgcc attctactgg ctgaacttga ttgatcgctt tttcaagcat
    48661 aggaataaac cttgctgcta cagcttcgtg aattaccaat ccctcagctg cattgcaaac
    48721 acttgggcgc tttgttttag cgttgataac aatcttagta gctatatcta agtcagcttg
    48781 agcatccaca tagatatgca cattccccac acctgtttcg atgacaggca cttttgcttt
    48841 ttccttaacg gtctgaatta atttagcacc accacgtgga atcaaaacat ctacataatc
    48901 cgttgcctgc atcaattctt cagcgacagc atgtgaggga tcctcaacta gctggacagc
    48961 atctggggtg atccctgatt tttccagact ttgtcggatc aacttcacca aagctttatt
    49021 tgagtgaagg gcatcttttc ctccccttag gatgatcgca ttattggttt tgaacgccag
    49081 actaaaagca tccactgaaa cattcggacg actctcaaaa atcatcgcaa tcacccctag
    49141 aggaactctc ttttggagga ttttaaggcc atcgaggtta gtatagccct taatgacttg
    49201 tccgattgga tcagctaagt cagcaacctg ttgaactccc tgtgctatcg ctttaatccg
    49261 ttctgaagtt aagcgcaagc gatccatcat gatgtcagaa ataccatgtt ctttagcatt
    49321 cgctaaatct ttttggttag cggctaagag agtctgtgta tcgtcaacta atgcctttgc
    49381 taaggtgctt aaaaagcgat ttttaatttg cgtcgacaaa ggtgctatta aaagactagc
    49441 ttgttttgcc ctttgcccta accttctcat atcagtcatg ccttacctct tctatctgct
    49501 tgaaccaggt gcctagtggt tgcccttcaa gcactcttaa aatatctctg ggattagctc
    49561 cattcatcaa gaccatctgt cctttgtttt caaataccat ctgagcagac tgcaccttac
    49621 ttagcatccc acctgtgcca aacttactgc ccgcaccacc tgctgacgca atgatttctt
    49681 gcgtaatatt agcaacatgg ctgcgtagct gcgcatcctc ataaatagta gggtttttat
    49741 caaaaaggcc atcaatatca gacaacatga ttaataaatc agcttttgta ataccagcaa
    49801 caacagcaga taaacggtca ttatctccaa atttagtcgc atgatccatt tcatccacac
    49861 taaccgcatc gttttcatta acaatcggca caatgcccaa actaatcaga ctttcaaaag
    49921 cattggtaac attggctaga ctttctggga aaaccaccac atctctcgtc aataaaattt
    49981 gtgacacgtt ggtttggtag tatgcaaaaa tttgtgaata aagactcatc atggctacct
    50041 gaccaacact ggaaactgcc tgttgtttag caagattggt cggacgtttt tccattttca
    50101 aaatatctag tccaaatccc atcgctcccg atgatactaa aataacttcc ttgcccttat
    50161 tcatcaaact tgaaatcaca aaagccagtt ggtcgatttt ttctaaatta attttacctg
    50221 ttggtagcac taatgaacta gtgccaattt taattacgat acgtgttaca tcttcaaatt
    50281 gtcgtttcat catacccaaa ttatagcata aaaaacagcc ccagaggact gtttttccga
    50341 ataatgatcc ctcttcgtta aagcctctct aagcttttcc agaaggtttt ttgaatccat
    50401 aattgcgcaa gacctaaaac cattagtatt agacaactca atagaatact aatcaacaga
    50461 ggttgttgga taatattggc aatgataaca gctccaaaac ctagcacacc tgcaactatt
    50521 aaattaccaa agataagtcc cattgttaac cattgcccat ctcctctggt aaagagttgc
    50581 gtcatgtctt gccattttaa atccagaagc cggtagtcac gacgatacat caattcccct
    50641 tgcacaatca gtgatagggc gtagccaaga caaaaagcaa tcgttagaag aggatgcagg
    50701 tgcaacacaa agagaccaaa cacaagataa atcaccatag gcacaatcag ctgcagacct
    50761 acaagcaagc aaaatttatc catcaagaat ttttttaacg ttattggtaa gcttttaata
    50821 aaggtaaagt tatccttttc aagtgaaata cctactccaa taaagctggt tggtgttgca
    50881 cacatgacac ccaaactaac cccaaataat aaggctaccc caaagtaatc tggggaaata
    50941 tgcttaaaga aacctgtgcc acgtgacaaa cttggaccga taaaaagcat cacatacatc
    51001 aggggcatga gataggtttg tgtcagtaaa gttgcatttt gtaacgttaa taggtgatgt
    51061 tttcgcaaca actgcgccag tgattgattc tgatgaggac gattaactgg ttttttagtt
    51121 tgcttgactt tgttctcgtt actaatataa aaagcctcac gataataagt tggcatcact
    51181 tttgtgacaa taccatatac catagctagg ataagtaaca atggcaacca aaagttaagg
    51241 agggccgcag tagaaaacgg tgcctgaaca acatcataga atcctttgaa atagggaata
    51301 gttgggtaat cagtaaatac gccatccgtc atcgtacgct tgttgttact aatattaatc
    51361 gcaaaaatta agacgaaagc gccaaaagtt gagacaaaca tcatgatagt tgaaatgagt
    51421 tttcgtttgc gacttcttac aatgattttg cctacccaag cattgatata aatagctaat
    51481 accatagaac tcactagtaa cactaaaaag agcacgatag ctactaaaat agacaaagga
    51541 tttcccaaga gttgccaata ggcaattaag agaagagaga taagaggcat caaaaagaca
    51601 gcacccatcc ctagcgacga gacaattttt gcaatataga gttcttctga cgttactggt
    51661 aagtgaatat aaagttttag gtcattactt tcataaaaaa tggtgtaaag agagctaaag
    51721 gctgtcaagg ttgacatgat aaaaaacata gcaacgtcaa aggagaaaag tcctggataa
    51781 tgactgaaat cgacaccaat aaacataaaa aggtaaatca ccaaaaacat ggcaatcatt
    51841 aaggcctgtt gccttatcat gcttttatag gctttgaagt tttctttcgg gtgtttttcc
    51901 tgacgctttt tgaggttagc taaactttgt ggattggaat aaagaatgtt tatcttgata
    51961 agttcccaaa tagtagacca attcatgcca tcacccctct tcttgcgcct tacgcccagc
    52021 gagttcaagg tagatgctct ccaagtcttt gtcaggatgg tgttctttca actcatcaat
    52081 cgttccaaca aaaatcaatt tccctttttt tagaatcccg atacgatcac ataactgctc
    52141 agcgactgat agcacgtgag tcgaaaataa gactgtatgt ccagaagctg catgagcttt
    52201 catcatttct ttaaggtcaa aagaagcctg aggatccaaa cctgttaatg gttcatccaa
    52261 aatccagatg ttaggatttg atacaagagc accaatcaca atcacttttt ggcgcatccc
    52321 atgtgagaaa ctatcaatgg tttgattaac ttcttccttc agttcaaaaa gtgttgtcag
    52381 ctgtgctaac cgttcttctc tgtcctcatc tgacacccca taaattttag ctaaaaactg
    52441 ccaatactca tttggagtta gattcaagaa aatatcagga gaatctggca cataagcaat
    52501 ttgttttttg atagcttctc tattttctgt cagaagttga ccatccacaa atacttcgcc
    52561 ataactcgct tcgataatag aagtcaaaat gctgatggtc gtggttttac ctgcaccatt
    52621 atgtccgata aggccaaaaa tttcaccgtc attgatggtg acgtttaaat cgctgagagc
    52681 ttctttgtcg ccatacaact ttgaaacatg tttaaattct atcatggtat cctttttcct
    52741 tttcttctct ttttctccct agactaatga ggcttcctct aaaatatact tttccaatga
    52801 ctgcttaaaa cggcaaagcg attttggaag taaaatgtca ttatcaagta agtaattatc
    52861 cacatcttgg tttagttggt aggcaacaag aagtgggtta ctgtgtttaa ttaatctatt
    52921 agaagctgct aaaagtagct gcgacaaggc cacattttca cgattttctg gataatcata
    52981 agcctgtcta atcacatcgt ataagcgctg tcgtttcttt tccatttata ctcctttatt
    53041 ttttgtactt ttacgctaat acaataacaa ttaaattata atttttatga atcgttttgt
    53101 caatgacttc ttatcaaaag aagtgtatta ggcagtttga ggaaaagaaa gaactgggta
    53161 ttttatttta aaaaaacaga gtaaatcaaa tgatttactc tgtttgggat gtttaactta
    53221 gagtgatttg tataactcag ttgcatttgc cacagtgaaa ccatattctt cgaagatacg
    53281 atttcctgga gctgaagcac cccaagtgtc aatggtcaat gtttttcctg ataggccgac
    53341 atattttgcc cagccaaagc ttgaacctgc ttcgatagcg agacgtttag tcacagctgc
    53401 tggtaggatg ctttctttat actctgctga ctgttcgtca aagatatttt gtgatggcat
    53461 agatacgaca cgcacatgaa tgccttctgc ttcaagagct tcttgagtat ccattgccag
    53521 tttcacttct gaacctgttg caatcaagat accatcaagg tcgcctttgg cttctgacaa
    53581 gatataagct cctttgctaa gaccatcttc tgccaattct tttgtgccct caagcactgg
    53641 aaggttttga cgcgtcaata caagcatggt tgggcgatct gtttcagcaa tggcacgttt
    53701 ccaagcagca tttgtttcgt taccgtctgc tggacgaata acgttcaagt taggcattga
    53761 gcgaacactt gccaattgtt caattggttc gtgcgttggc ccatcttcac cgacagcgat
    53821 agaatcatgt gtcatgacat aaactgttgg caagttttgg agcgctgcca tacgaacagc
    53881 tggaagaaga tagtttgaga agacaaagaa ggttccgccg taaacgcgtg tcccgccgtg
    53941 aagggcaata ccgttcatgg ctgcagccat ggcaaattca cgaacgccaa accagatgtt
    54001 acggccttcg tagtgacctg gttggaaatc tgtttcagcc ttaaccatag tattgtttga
    54061 agctgaaagg tctgctgacc caccccagaa agaggctact tgttctgaaa tttgttggat
    54121 ggcttgttga ctggatacac gactcgccat tgaactacca agttcgtgcg cttcaagttc
    54181 tacttgagca gcttcgttag taaaggcttt ttggtattct gctgctaatt ctggatattc
    54241 tgcttcataa gctgcaaaca agtcattcca ggcttgttct gctttttcac cacgcgcttg
    54301 aagaccttga gcaaagcgct ctgttacttc agcaggcact tcaaaatctt gatgagtcca
    54361 ttggtaagct tttttggcaa aagcaatgcc ttctgctcca agaggagcgc cgtgaacagc
    54421 tgaagttcct tgtttttcgg caccaaaacc aataatggtt ttgacttcga tgatggttgg
    54481 tttctcagtt tcagctttag ctgcttcaat agcagctgca atttcttcta aatcatttcc
    54541 atctttcaca aggatatgtt gccaaccata agcttcgaaa cgtcctttca catcttctgt
    54601 gaaagccata gaggttggac catcaagaga gatgtcgttt gaatcatata gcaagaccaa
    54661 tttcccaagt tttaaatgtc ctgccatact tgctgcttct tggctgaccc cttccataag
    54721 gtcaccgtca ccattcaaag caaatgtgta gtgatcaacg atgtcaaagc ctggtttgtt
    54781 aaatttagct gctagatgag cttctgccat ggccatccca acggcatttg cgatcccttg
    54841 accaagaggt cctgtggttg cttcgacacc gtctgtgtgg ttcacttctg ggtgacctgg
    54901 tgttttagaa ccccattgac ggaagttctt taaatcttct acagataaat cataaccagc
    54961 taagtgtaac aagctataaa gcatggcact tccatgacct gctgatagga taaaacggtc
    55021 tctgtttgac caattacggc ttgttttggg attgatgttc atgaagtgat tccaaagaac
    55081 ataggccata ggtgctgccc ccattggaag tcctgggtgt ccagaatttg ccgcttgaat
    55141 ggcatccatt gatagggtgc ggacagtgtt tactgccaac tggtcaattg catcaaatgt
    55201 cataagtaaa acctctctgt ttattacaac taaaattaaa cgttttctat tgtctattgt
    55261 atcacaaaaa tagacgcttt tttcagaaaa tcctccaaag tccctaaatt ctttttctct
    55321 attttgccag aaaaaaacta gtttggacat cattgatgga ttctttttga cgatgaatat
    55381 aagagagcct gttgacacag tggccacaga ctctttagcc ttatttttta aaggaagccc
    55441 aatcttccat aaaggttttc aaaccatttg tcgttaaggg atgttgcgtc atcttagcaa
    55501 acaaggggtc tggaatcgtc gcaatgtgtg cgcctaattt agcaacagct tccacatggg
    55561 ctgttgtacg aatacttgct gcgatgattt ctgcttggaa atcgtacaag tcaatgattt
    55621 cacgaaggtc gctgattaat tgataagcat ctgtgccaat atcttccaaa cgaccgataa
    55681 atgggctaat gtaagttgcg cctgctttca ttgccattaa accttggctt actgtgaaaa
    55741 tcaaggtcac attagtttta atcccttctt ttgaaagaat gtttgttgct tttaaccctt
    55801 ctgtagtcat tggaatttta acgacgacat tgtcatgcca cttagcaatg cttctagctt
    55861 cttctaccat agcatctgct gttagccctg tcacttcagc actgattggg ccatcgacga
    55921 tgtcacagat ttctttgata actgtttcaa aatcacgtcc ttcacgtgag ataatggttg
    55981 gattggtggt gacaccatct acaacgccaa gttcattaat cgctttaata gcggctacat
    56041 tagctgtatc taggaaaaat ttcatttctt acctccaaaa attttcgatt ttgttaagct
    56101 ctatttgata agctttttca aatcatctac ctttagacta tcctacttta ttattataaa
    56161 agtgtaacag tccttagaaa agaccaagta tcacacagtt ttgtgtgcaa aactagactt
    56221 agctgctggg ctgagtgaga gttcctcttc tcgtgtattt ttttgctgga aaaggtcttt
    56281 gagaaaagct tctaaagcag tgagttcata gggggagcta tactgtttta accggtaata
    56341 gggtaaatct tgtctcggta aacagacagt ctgataggta atcagacaat cataaacttt
    56401 ctgatgatca tagggcatta attgaaaatc cctacgatgc cccaaatgac gtctaatggc
    56461 caattccgca atggctgctt ccaccttatt ttgccccaag gcaagcccta ctaaaagagg
    56521 ctcatggtgg cgctcaatgg aaaaaatcaa caatgctaaa acgtcgtcac tcaactgctg
    56581 actgaaatcc gtttcctgat ccatttgcag cactaaatgg tttatgataa cccttaaaag
    56641 cgctctttta tcttcgccta ctaattgata aaggtattgg ctattggttg gttgactaag
    56701 gatagctcct ttaaaaaagt aagctttgga aaaaaatatc cccaagccat aaatgatttc
    56761 ctcctttgtc tgatggataa tcacatgagc cttctttaaa agccataagg cttctgaaat
    56821 gtgatcagca ataggacctc caaaacccaa actatacttc atgctggcaa taggaagtag
    56881 aggataagca tgcaaaaaga caaagaggct cttagcttca aaagcatcaa attcaagggc
    56941 atagcgtctt aagtaatgta aaagcatgct ttctaagcgc ttaaagaaaa tattagatgt
    57001 cataaagtca ctatctctta aaaaatgatc attgtagcct ttttgaaagg acattcgcgc
    57061 ttgcgaaatc gccaaccaaa tcaataattg ttctaaggct tctgccgata atgactggcc
    57121 aatcagccgc tcaattaagg tagccaaatg cgaagcgtct aactgattga ccaaggcgtc
    57181 tatgccttgt ctggtcaagg tatggcggaa caattcaaaa tagaaataac gccactgaag
    57241 ctcacttccc agttgtctgc cttgcgagag cgccagatca aattctgata aaagctggtt
    57301 gaggtgagct aattgtctgt ttagagtagc ttcactaacc atcagttcaa cggataagtt
    57361 ggtgatgtta aagtgttcat ggcagtacat gtaggtcaat atctgatagg caaccgattc
    57421 tttgagaagc agagctacca aatcctccca atggaactgg ccattttctt ttaagctcag
    57481 actgtctttt tctaaaagta attgacaggc taaaccttgt tctcgacaca aatgatttag
    57541 attgtcaatg tattttaata gggtcacttt agacaagttt gatagcctca ttaggtcttt
    57601 tagccttaac gtttctttag catgataaag ggtcaccaag agacgatatt gggcccttcg
    57661 ttccttatcc attaagtctt caatcttcat ggcggagcct cttttcaaat aatttgagac
    57721 aagcttcatg aagatgataa gccaaatcac tgtgaccttg taaaaagaga aaatcttgaa
    57781 atgctaagtc agcgtctgta actttcagag ccagagcctg acctaattga ttggcgatga
    57841 caagagcatt ggttttggat aggagctgag cgcctattaa aatcccatcc gtttttctag
    57901 ctattaattt cagccaaaag aggtttttag aatccccatt ttggtacaaa tagctacacg
    57961 tatccatata aagctctgct tcttcttctg tcacaccaac actcgcgcga taataatcaa
    58021 agtgagaact tcctaatacc ttgaccgtct gtaatggagg aataggatat ccagctaaat
    58081 gcagagccag agcctgacct gtcttcattg cttggttaat caaaggtgta tagtaatcca
    58141 ttcccaatat accaaaatgc aatgaaacca tgtctccaat ggcatagata ttagcctggc
    58201 tggtctgtaa gttttcatta accaaaatgg tcttatccag agcacaagcc acttgtcctt
    58261 gcaaaaggtg tgtatttggc ctaaagttaa tggctaaaat agccaaatca ccttggaagg
    58321 tgtccccttg ctcggtatga gcgacaactt ttccctctat ctcatgaata gccgtaacac
    58381 gcttattatt aataaaggtg acatggtgag tggacatttc tgccattaca ggggctatca
    58441 gttctgcgtc agtctgatag aaatctggac gttcggctgc ttcaatcagt ttgacccgtt
    58501 tgccttgtaa ggacaaactg taggcaaggt ctaagccaat caagccggca ccaataacca
    58561 agacctcttg gctagcctca atcagtttta aactagcttg gctttcttca taatatttgg
    58621 ttaccaaaac tttgttggtc tgtgacgtct caatataatg agactggggg ctagcaccca
    58681 tggcacaaac aagcgtttca taaccttctt caaaaactcg tccttgactg tctttgagaa
    58741 gcaaggtgtt tgagggagct tcgatagcta acacttctgc ttgaataaac cgatggttag
    58801 actctatttg tgctgctagg caggctcttc cccacatagc atcagacagg tcttgaatgt
    58861 ctcctctgaa taattggttg ataccatttg gaatataatt gggacagctt tccttatcaa
    58921 tgagaatgat ttgggaatct ggattgaggt ccttatattt atcaacaaag gctagaccag
    58981 caaaggatgc cccgataaca tgtatggtct ttgtcgttaa tgtcataata gtattattat
    59041 agcagttttt tttaagatat gaaagcgttt tacctaatcc tataaagaaa atgcaaagga
    59101 gctggcctat gatagccaac ccctttagtg atggttagga catgacttgg aaaagcaaaa
    59161 ctgctaagac cgctccaata attggtccta caacaggtat ccaagcataa gaccaatcag
    59221 aatctccctt gttgttgagt ggtagaatag catgaactag acgaggtcct aaatcacgtg
    59281 ctgggttaat ggcgtaacct gtcgttcctc ctaaggataa cccaatccca ataaccaagg
    59341 tacctacaca gagggttcct agtcctgctg gcatatcata taagccaaat gccaaaatac
    59401 caagcatcaa gacaaaggtc ccaaagattt cactcaatag gtttgagcta gtatctcgaa
    59461 tagcaggacc tgtcgcaaat gtccctaaaa tatcagcctg actctcagca gccagataat
    59521 gtggcctgaa ctgaaggaat accagagttg aaccaaccat agctcccaat agttgggcaa
    59581 ggctataggc aatggctgtt gaccaggcaa tggttccact catggcaaaa gcaaggctaa
    59641 cagctggatt gaggtgggca ggggcaactt tgccactgat aaaggctgcc acagcaactg
    59701 caattcccca gccagtcgca atcacgatcc agccagaagc atgggttttc gttttgggca
    59761 agacaacccc tgctaccaca ccatttccta gtaaaaccaa taaggctgta cccaaaaatt
    59821 cgccaaagat atccatatta accctcctga tggcctttta aggcactcaa atcattgtct
    59881 gcaatcacgc gacgaagatc gtcttcttgt gccactcttt cctgatcaga ccattcaaaa
    59941 tgtttagcca tttcattaat cactgggtca atcaaagcat ctaggctatc tcgcataaat
    60001 aagaggtgat ttgttcttct caagaaataa tctgtcggtt taagagccat ttcataatcc
    60061 atcgcataat gtaaggacaa ggtttcagct aaacttaacc cttcagctgc tgttaattga
    60121 cgagttaagg caaagacttt tggcgcatta gaaccataaa ggtttgccaa atacctagca
    60181 tcatccatcg aaagaccact aagagttcct aattgagcat aggcttctat ttccgaatct
    60241 acattggctg gattgatttc acctcctgaa acaggatagg tttttgaatt gataagcttg
    60301 aaggatttgc caaactcttc tttgaggatt tgaataatcc ctgtcaatgc tccttcagcc
    60361 attttgcgat agtcggtaat cttaccacct gccaaggtaa agagtccatt ctcatcacgc
    60421 tcaaaacttg aacctcgtga cactgcagac ggatccaatt ctttttcaga tgtgctggtt
    60481 tcaacctgct taatagcttt ttcaacagct tctcggctat cttcgtggtt aatataggct
    60541 ttgacagtat caaccaagtg atcaaaacta tcatcactga ctttaccgct gttgccacca
    60601 ttgtagtcag aagcactatt acctgataac aaggggcgaa gaccagccca actgctttca
    60661 atatcatcaa tggtcacgtt ggcatttgga aagcggttat tgacaacgcc taacaaataa
    60721 tccacatctt cttgagtaac ttgtgggtgc tccaagtctc cagtgtagtc cgtgtccgtt
    60781 gttccaaaat aagttttttc ctcacgtggc aagacaaaga ccatacgacc atcatttaac
    60841 cctgtgtcaa catagacagg ttgagacact ggtaattttt gacggtccac taccagatgc
    60901 accccttttg tagggcgcat ttgatgaatc ggttgtccct tatgagagaa ttgacgaatc
    60961 tcatcactcc atggacctgt ggtgttgatg actaatttag ccttgataat gatttcttga
    61021 tctgacagca gatcacgcgc cttcacacca ataatcttac cattgtcatc tagcaagaaa
    61081 tcttctgctt tcacatgact agcaataaga gccccatcac gattagctcg tttgatattt
    61141 tcaataacaa gccttgcgtc attattgcgg aaatcaaggt aaaccccacc accaagcaag
    61201 ccttcttgtt ttaagtctgg ttctcgtttt aagacttctt ctttggttaa caccttgttg
    61261 gccgctggcg tattggacac gcctgctaaa agatcataca aatccatagc gaccttcaaa
    61321 cggaacatgc taaaggtact gccaggttcg tcataaacag gtaataacat agggtctggt
    61381 tttggaatgt ggggtgcaat ttgttgcacc acagcccgct ctgacaccgt atctgaaacc
    61441 acctccacat caaattgttt caagtaacga agccccccgt gaaccaattt ggttgaacgg
    61501 ctagaggttc cttgagcaaa atcttgcatc tcaatcagac ccgtatctag gccactagct
    61561 gccgcctgaa gtgccacacc agcacccgta atacctcccc caataatcag taggtctaaa
    61621 tctctttctt gcattttttg gagagctaag cgtcttgttt ctcttgaaaa ttccattcca
    61681 tcctcctcta gttattttgc atcgtcatct gcatcttctt cttgggtgaa aacttgagtt
    61741 gctttaacag cgcgcttcca acccttgtat aatttttctt tgcgcgattc attcatgcta
    61801 gccttaaaga gctggcctgt ggcatttaat tctttcaaag catccatatc ttcccaatac
    61861 cccacagcaa gccctgctaa gaaagctgct cctagagctg ttgtttctaa atttttagca
    61921 cgggcaatat caattcctaa aatatcagcc tgaaattgca tgagcatatt attcatggct
    61981 gcaccgccat ccacacggag ctgttgaatg tcaatacctg aatccacctg catggtatca
    62041 ataacatctc gcacttgata ggcgatagat tgtaaggttg ctttgacaaa gtcttctttg
    62101 ctggtaccac gtgtcaagcc aaagacagat ccacgcgcat tagaatccca gtaaggagct
    62161 cctaaaccgg taaaagcagg cacaacataa acttcatcgt cactagttga tgctagagcg
    62221 aactgttcag attctggtga agtctcaatc attttaagac catctcgcaa ccattgaatg
    62281 gcagagcctg caataaagat ggaaccttcc aaggcatagt gaaccttccc attaatcccg
    62341 taaccaatgg tggtcaaaag attattactc gataactgca tctcatcacc agtattcatg
    62401 ataatgaaag aacctgtgcc ataagtgttt ttcaccatac caggctcaaa agctagttgg
    62461 ccaaacaaag ctgcctgttg gtcacccgcc atacctgaaa taggcacttc gcccccataa
    62521 aaatgaaagg cagctgtttt gccataaatt tcagaattgg atttaacctc tggaagcata
    62581 tcttttggaa tatttaaaag ctctaaaatc tcatcatccc atgttaagtc tttaatatta
    62641 tagagcatgg tacgagccgc attggaataa tccgtcacat gaacagcacc atctgtcaat
    62701 ttccaaacca gccaagtatc aatggttcca aaaagtaact cgcctttttc agctcgttct
    62761 tgagcaccag gaacatggtc caaaatccaa cggatcttgg ttgcagaaaa gtaagcatca
    62821 ataacaaggc ctgtcttttc atggatcatt tttgtatggc catcttgttt gagttgctca
    62881 gcaattggtg ccgtctgccg tgattgccac acaatagcat tataaatagg tacacccgtt
    62941 tttttgtccc aaaccactgt ggtctcacgt tggttggtaa ttccgattgc ttcaatttgg
    63001 cttggtttga tgctagactc aataaaagca cccgcaataa cagactgaac cgaattccaa
    63061 atctgattag cattgtgctc tacccaacca gcgtgtggga aaatctgagg gaattctttt
    63121 tggctactgc taaccttttc ccctttttga ttgaaaataa tcgctcgtga acttgttgtt
    63181 ccctgatcaa tagccatgat atacttttct tgcgacattc attaccctcc tttaagtaag
    63241 cgttttccta tttgattcta ttatagctaa ttttatcaga aatatattat caagaatttt
    63301 taaagctaaa aaaaaagctg ataagatagg tagcttatcc cactagatga acttgaaaaa
    63361 tccactgatg acaaccacgt ctcctcattt ctaacgaggt aatctttctt atcaaagaaa
    63421 atcaaaagac ccaacaatca ctctgctaat ccagagtcat cattgggtca taaagagaac
    63481 taagcctcaa aggcaacacg gtatcaaaca gccgcgccta agaggcaaag acaattggac
    63541 acaagagtta aggctgtctt attcattaca gtccttgatt agtcattgat tggttcagaa
    63601 gatttttcca caatatcccc tgagttggcg tcaatggtat agctgtattc ttgatctttg
    63661 ttttgaaact cgatttcata cacggctttg ccatcttcat tatcttgtgt aactgatagc
    63721 atttgagcat cagcttccgt aacagaagca tcttttaacg caattgattt ggctttgtct
    63781 tctgagagtt taactttctt gctagtttga cttgtctttg gttgattatc catatgatcg
    63841 tctttatcat ccatatcaca ggctgcaaga ctgagtaaag agaggctggc tatggctagt
    63901 agagagaatt ttttaattgt cataagtact accttctttc tttgatttct tctattataa
    63961 ctcaaacaca tggtttttcc caatattttg actatacaat ataaaaacgt gtggtcactt
    64021 tgaagtatca taccatttaa aataaaagct aacagtcatc acgataaaca aaaagcagtt
    64081 cagagctgct ttttgtctta tgattttggg tcatctaatg aacggccgtg caagcctttt
    64141 tcacgttgca cctgtcttaa tttttcaggg gtcacgtcgt ttccttcttc gtccaccaat
    64201 ttgatgcctt cgatatggtg tctgacagag cgacgatagc cttcaatgta ttcttcacgg
    64261 agttttgcct gttccacttt ttcaggtcca gtcaagccta ccgttttttt ctttttagcc
    64321 agctcattga tacgagcaat ttttttagga tccatgttaa gccactaaga gcctgggaaa
    64381 aaagtataag gcttaaaaaa ctgacttgac tctcactgtg aaaagcaatg tttaaaggcc
    64441 ttgttttttc cactcgggta ctgaactcac ttttctagct aagtccccaa cggctctttc
    64501 ctttctattt acttggtgtt tagttggtta aaagcaacaa tggtcttagc tttgcttact
    64561 aaatctgata aaatagctaa acggttgttt ttaagggctt gatctcctgc cataaccatt
    64621 gtgttatcaa agaaatcatt aatcactggg ctaagggcaa agacctgttc taactgctgg
    64681 gcagcactgc ctgctagagt caagccttga atagctgcaa acaaagtgtt ttcttgctca
    64741 ttttcaaaga ggctagggtc cacctgaaca gaagcgtccg ctttttctgc caaattaaaa
    64801 gcacgtgaca aagattcaac tgctggtttg taattttccg tatgactggc tttgacaaga
    64861 gcttcagctg cggccaacat ttctggaacc acaaaggttg aacttgctag aatagcttcc
    64921 cgaatgtctt ttggtgcggc tttgcccatc atcttatcca cacgagcacg gataaagttc
    64981 atcacatccg ccttattggc ataggtcaaa ctatcaaagg acaagtcata taagctatct
    65041 accagcttat ccattgggat gcgccatcca aaatgatcaa gaatacggac aatcccttgg
    65101 gttgcacgac gtagagcata aggatcatta gagccagatg gaatcaagcc aacagaaaag
    65161 aatgacaaga gagtatccaa tttagctgcc aaggccagga cagcgccaac tttggtttca
    65221 ggtagcgcac ctcctgcagc atcaggtaag tagtgttcac ggattgctgt tgccacagca
    65281 gcatcttcac cagctagaag ggcatatttt tcacccataa tcccttgcag ctcatcaaat
    65341 tcacccacca tacctgttaa caggtcaaat ttgtaaattt gggcagcacg gtcaacagct
    65401 gtgacttcct cagcagatag gttggcttcc ttagcaagtg atgcggcaat gacacgcgta
    65461 cgatccatgt gttcagcaag agagccgatt ttttcatgga aggtcacatt ggtcaatttg
    65521 gcaaccaaat cagcaatttg caatttctga tcctcacgcc agaagaattc accatcttct
    65581 aagcgagcta ccaaaacttt ttcgttccct ttaataacat tttcaatggc ttgatcattc
    65641 ccattacgaa ctgatacaaa gtttggcatc aagtgaccag cctgatcacg tactacaaaa
    65701 taacgttggt ggtttttcat tgatgttacc aatacttctt ctgggacatc aaggtattta
    65761 gcctcaaaac ttcccatgaa agctgttgga aactcgacca agttcaaaac ttcattaagc
    65821 aagtcttcgt caatgtcaac ttgcacaccc tgctccactt caagcgtctt gatttgctcc
    65881 acaatcatct cttgacgctc tttagcatca gcgataacaa actggctgcg taaatcagcc
    65941 tcataagaat cagcacttgt gatagtggtt tcagtaccta aaaaacggtg accacggctg
    66001 acgcgtccag aatgaatatc caagaagtca agttccaagg cctcatcatt caacagaact
    66061 gtcaaggtgt gaacaggacg aatgtattca aaactattgt tagcccagtg catgctgact
    66121 gggaaggtca ttgctgataa cacttcagta acgcctagaa gcacttcctt agcaggtttt
    66181 ccagcttcgt gtttggtcac ataaacgtat tcttctcctt tgacttcgcg gaattcgata
    66241 gcatctgtgg tcaagccttt gccacgaaca aatccttgag cagcttttga gaaattccca
    66301 tcagcatcaa gggcaatttt cttagcaggc cctttaaagt cctcagtcaa atccgtttgc
    66361 tgatcagcta atccagacac acgcactgcc aaacggcgtg gagttgaaaa ggtttgtata
    66421 tcttcaaaag agagacgatt ttctgttaag aaagtcgcca agcgctctcc cagttgtttt
    66481 tcacttggtg tgaccacgta ggctggaagt tcttccagac caagttcgat tagtagattt
    66541 ttactcataa ttaagatacc aagggcgtta agcggacacc atcaaaatag caaagcgacg
    66601 caggtgcttg cacctaggaa gtcttggtct ttttgacata gtccgtagcc cgtgttcagt
    66661 tcctttctct aaaaagtatc tttttgattg ttcccttagg taggggggac gcaaagtgaa
    66721 attatccagt ggataatttc agaaaacaaa agtgttccat tcctagttag ccagcctaaa
    66781 gtctagccaa ctccctcgtt cgataagtaa ccttaccgaa ttgtcactac agcgggagta
    66841 accttgactc ggcgaccttc ggtcgcccac ttcttgctcg ctcttaagat tacaaagctc
    66901 gcaactagat catctttaaa tcgacttatt cgtcatcttc agctagcaag attgcgcgtg
    66961 ttgcttcatc caacagtgga aatccaagct tcttgcgttc tgcaacaaag gtcttagcaa
    67021 cgacacgtgc caaattacgg atacgagcaa tgtagcctgc acgttctgtg acggaaacag
    67081 cgccacgggc atccagcagg ttaaacgtat gagaacattt gagcacgtaa tcataagctg
    67141 ggtgaaccaa accttcttct agggcacgcg aggcttcttt ttcaaacttt tcaaagtttt
    67201 caagcagcat gtcttggtct gatatttcga aggaatattt tgaatgctca tactcaggtt
    67261 gtaagaagat ttcaccatat ttaacacctg gtgcccactc aatatcatag accgaatcca
    67321 cttcttgaat ataggaagct aagcgctcaa gaccataagt tacttctgct gtcactggag
    67381 atgtcgcaag gccaccaact tgttggaaat acgtaaattg tgtgatttcc attccatcaa
    67441 gccaaacttc ccaaccaagc cctgctgatc ctgttgatgg gttttcccag ttatcttcaa
    67501 caaaacgaat atcatgttct aaaggattga tgcccaattt ttccaaagaa gcaaggtaaa
    67561 gttcttgaat atttgatggt gatggtttca tgaccacttg aaattggtgg tgttggtaaa
    67621 gacgatttgg gttttctccg taacggccat ctgcaggacg acgtgatggc tctacataag
    67681 ccgcattcca tggctcagga cctatagcac gtaagaacgt gtaaggactc atggtcccag
    67741 ctcctttttc attgtcatag gcttgcatga gcatacaacc ctgatcattc caatattgtt
    67801 gtaaggtcaa gatgatttct tgaaaggtaa gttttttaga catttcgtac tcctttgata
    67861 gtagtaaaat ggtatatcat tgacaatcgt ttttttgtca tcagtaaaat acctgacgat
    67921 gttactagca tgtattacag gtctaggcac caaaaaaccg cattttgatg ctcctaaatc
    67981 ataagaccta ggggcgtcaa aacgcggttc caccctaatt tattacttca tttatatagt
    68041 atctttttgg gcaatattga caaatatact taatcacact gcccaaacgg aagcgccaat
    68101 ctgcagtcct accattcggc tctaactacc ccgaactcgc tttagataag atacttgcat
    68161 cctttttcct agagtctagt ttagcataaa gccattagtt tgtccatcat gagcttaagg
    68221 ttttgttcga gtaccgtttg gaataatcac ttccgctaat agcttgtttt cttctcgaat
    68281 acgtaaatat attactacaa tgtagcatgg gaaaagaagc atagccgtaa ttttagcatg
    68341 gcaaagtaag gctatgccca ccagctcagg ggcgatattt aaaaagtagt taggatgttt
    68401 aatcgttttg aacaaccagt gatccacata tttgtggtct tttgctaaca tcaattttac
    68461 agtccaaatg tcacctaaga tacgtgtcac ttcatataaa acagctactg ataataacat
    68521 caacaaaaga cctaaaaaac taatgccatc aaacttaatt tgtttaagca gcgcttcaat
    68581 caccgcaaac acataaatca taatgtgaag taacgtcaaa aatttcgtgt tctgagcacc
    68641 aaattcctgt cctccttggg ctaatatggc tttttcattt gttatcgatt tcttcaaaaa
    68701 tactaaacga atagtaaaca tagctaacat cactaaaaag atggtcacaa tacggctcct
    68761 tattttcaat aatagtttct ttcacaaaac actaataaag attatagcta aatgataaac
    68821 ctttgtcaaa ccgttttcaa aaaagattta gcgaattatg gctaaatctt tgtagttcct
    68881 taaaaacttg tagtatcagg ggtaggaatc gctgacattc ctgagagata gcgaattgtt
    68941 tttttatctt cttgtgtcaa gctcacatca aaaatagcca tattttcctt gatgcgctca
    69001 tcatgcaccg attttggcaa gggaataaaa ccttctgcca gcgaccaagc taaggcaact
    69061 tgtgccactg ttttgtcata tttattagct aactgctgca tagtctcatt atcaaaaatc
    69121 tccccttgtc ctagaggact ccaagcttcc aataaaatct catttgcctt acaataatca
    69181 accacttcct tttgatagca acctggggct aatcgaatct gattaattgc tggagttatt
    69241 ttagctgtct cttgaagagc ttctagatga tgcaccataa aattgctgac gccaatgctt
    69301 ttaataagcc ctgcttcaac cgcctcttcc atatattgcc atgcttgggc atttgcctct
    69361 ttccaagtgt tacgcagagc ttttgggttt ggccaatgga taagatagag atccacataa
    69421 tccagaccaa gacggtcaag agaagcagct aaagcgtctt ttgccccttc ataactatgg
    69481 gcgtcattcc agagtttagt tgtaataaat aagtcttctc gtagaacccc agaatccttg
    69541 atggcacgac ccacactttc ttcattttta taaatagctg cagtatcaat atgacgatag
    69601 ccagccttga tggctgctaa ggtagattgg taagcttcct caccatcggc tgcttggtaa
    69661 gttccaaatc ctaaaacggg aatctcatag ccacttgtca tttttactgt tgttaccatc
    69721 acaaaaacct ccttttatca atatctgtaa gcgattactt taatctattc tatcataaag
    69781 aaagaaaata caaaaagaat tggcctgcca gacatagcta ccccaatcct tttgtatctc
    69841 ttaggcatca aaagcttttt gcccatttaa ataggttgca acaagtgtta aatccttatc
    69901 aagaacaata aagtcagccg catgcccagc tttgatttga ccacatacgt cgtcaatacc
    69961 gacagaaaca gctggcacat aagttgccat atgaatggct tctgccggag ttgcgattcc
    70021 ccaggccact acatttctaa ggccatcttt taatttcaaa atagatcctg ccaagtttcc
    70081 actctcttta agacgagcag tgccatttgc cacaaccaca gagaattccc ccaagaggta
    70141 atcaccatct ggtgaaccac ctgctcgcat acagtccgta atcatggcta catgatcatg
    70201 ccctttttgc tgcatcaaaa tatcacaagc aattggtgag acatggtggc catcacaaat
    70261 caactctgcg taagtatttg gaagattata aaccgctccc accattcctg gttcacggtg
    70321 ggtcaatcct cgcatgccat tataagcatg aacccaaaca ctagcaccag cttgaacagc
    70381 ttctttagcc tcttgataag taccgtttga atgccctaag gccactgtta cgccttgttt
    70441 tgtcactgca gacacaaatt ctttgacacc atcacgttca ggagcaaggg caattttttt
    70501 gatgagccct ttagcagctt tttgccaagc atcaaattcc tccaagcgtg gggttttcat
    70561 ataacttggg ttttgagcac ccttatattc ttcggtaaaa taaggacctt caaagtagat
    70621 accttgtatt ttagcacctt ttacctgatc agcaactgaa gcaatagtcc ctgatacttt
    70681 ttctaactgc tcaaaggtag aagttaaggt cgtcggtaaa aaagacgtta ctcctgttgc
    70741 taatagtcct tcactcattt gatgaatccc ttgggcagaa ttatccatga catcagctcc
    70801 cgcatagcca tggatatgcg tatccacaag acctggtgca atttgataac cggtgtagtc
    70861 aatgatttgc gcatctgccg gaacaatttc tgtccactcc ccaaaaacac catcatgaag
    70921 acttaggtag ccagccggtc tcacctctgt tgggtaataa aaacaatctg ctttaagata
    70981 gcatgtcatc ttttttcctc ccttttttcc ttattatacg ccttattctt tactttgtaa
    71041 atggtatata ccacttttgg gattcaaaaa agaaaacgtg gatgatcatt cacgttttct
    71101 ctttttttaa agctggtgtg aaagtacttt ctctgctaaa ttcaaggcat gatctgtgat
    71161 gcgggtatag tgggaaataa tatcaataaa attaatacct gcttgtgccg tacattctcc
    71221 acaattcaag cgcttaatgt gggttttacg taatcgtcgc tctttttctt caatttcttt
    71281 atggcgagtc acaatagttt gcgccaagtc tgtatcacta tcaacgatag ctctaatggc
    71341 atccagtgtt aaacaatgcg tcaattgata catctctgtc aattcttgac gagcagatat
    71401 tgaaaaacca atttgtttag atatgatgcc ttcaattaga atgcctaaag actcagaatg
    71461 atctccaatt ctttccaaat cacgtgaaga gtcaagaata ccagccaaga cttcattttc
    71521 acttgggctg agggcttcgt tagaaatatc aaccaaataa gtggttaact cctcatcgat
    71581 ggtatcaact gctctttcat aacgcttgac cttttcccca aatttaccgt cagctgtcat
    71641 aatataactg taagaagctt caaaagcttg aatcgcataa gaggctaaat gaaccaattc
    71701 cttgtgggca tttcctagtg cgatagaagg ggcttgggta ataagtaagc gatctaaata
    71761 aagggcttcg tatttgacca cttcatcttc tcctggaatg agtctagtca caatcatagc
    71821 tagtagacta atgaaaggaa ttaataagat ggtattagtg atattaaaag aaccgtgaga
    71881 aaaagcgata gtcatctcag gcgttaaact caactttgat tgtagccata acatcaatga
    71941 tgtgaatggg actaggataa tcataaaaat aattgtaccg atcaaattaa ataacacatg
    72001 agctgctgcc acacgtttag cagcaatatt tgaacctata gctgctaaga cagctgtaat
    72061 gcaggttcct atatttgagc ctaacaaaat aggaatagcc ccctgtaagg tcaaaagacc
    72121 gcctgaaaac agtccctgta aaatcccgat aatggctgcc gatgactgaa tcaacatggt
    72181 caaagccgtt ccgataaaga caccttggaa gggtttatca cctaatgtcg ctaaataatt
    72241 ttgaaaggct gacacagatt tcaaaggatc catggcatct cccattaggt tcagcgagaa
    72301 gaaaattcct ccgacaccaa aaatgatacg cccaaaattg ttgagctttt tattagaggt
    72361 aaagaaaaga caggctgcac caataaaaat catgggcaag gcgtaatctc ctagtttaaa
    72421 accaattaaa aacgaagtga tagtcgttcc aatattagcc cccataacaa ttccaatggc
    72481 ttgtcgcaaa tttagcaaac ccgcagaaac caaaccaacc gtaattacag ttacgcctga
    72541 actggactga attaaggcag acatggcaat tccgactaag ataccaaaaa agggattact
    72601 ggtgtattta tcaatgtaat accttagttt atctcctgct gcttgttgca gaccatctcc
    72661 catatacttg atactgaaaa gaaagagacc taagcctcca aagaaatgaa atgcaatgtc
    72721 ttgccaattt actgacacaa tattgtcctc gctcaatttt ttagtctatt ctattttaat
    72781 gtattacggt ctttatcaca aggttttttt aagcgtttct gtgtataccg atgtcaacat
    72841 ttgcatatta ttggtttgat aaggtgttag gcttttccga tattttacat catttgtttt
    72901 tgcacaaatc ttttcatttc gtttaattag aggtataata tggctacgat gaaacaatat
    72961 cataaaggag attccatgac taaatcacaa aaagaggcgc tttattggat gttgagtgtt
    73021 ctaactatca ctctaatagg tggctcctgc cttatttttg gatcccaccc tcaaacgcaa
    73081 gataaggtag ctaaacattc taaaagtgct gctagtttac taaaaaaagc agttaaagca
    73141 gttaatgacg ctgatcgttt agccactgca gctgctatcc aagaagccca gaaagctgtt
    73201 gataaattag cagaatcttc taagaaaaaa acgctacaag aacagctaaa cgttgccaaa
    73261 gcaaagcaag agcaagaaga tgcagctact caagcagtta aagctgctga ggagactctc
    73321 aatcaaaatc ttaaagatat cgcccaaaaa gcagttaacg acttaagtaa caaaggtaaa
    73381 aaagccgctt tacaatctcg gttagacgct attttaccag cgaaacccat tattgatgaa
    73441 tttccaagac aaagtggaga aataacagat aactcttact ggacaccttt cccaggagac
    73501 gtctcagata cttatgataa ttcccagtca cctactttag acccaagctc agaatcttca
    73561 gcttcagatg ttacaccaca acctagtcat cctgatccaa ttccacctca gacctcttca
    73621 gaaccttccg actcaggaga caagcaatca tcaaaagagt aatacaacag tttttcgtaa
    73681 aatcaatcaa taaacgtttt agacggctat cttagtgatt agtcttcctg acatcttaaa
    73741 aaagctagct caaatcaaaa gagtctagct ttttgttttg ttagatagca ttaaatttcg
    73801 tagcccatta aaagtcctcc gtcttcagca taaaagctac acaaacctga ggtccttcca
    73861 gtttgaatca cagcatcagg atataaagat ttgatttttt cactgatctg ctcacaaatt
    73921 tttggatttt gagcatgagc aatgtaaact tttccgccta cataaccctc tttttgaatt
    73981 tcttctatca aggcagaaac tgcttttttt tgaccacgcg ctttttgaag aagttcaagc
    74041 gttcctttat tgctagcttt cccaaccatt ctaatattga gtaagccaat tactttacct
    74101 actaatttac tcagtcgacc atttttaacc aaattatcaa ccttggcaag cacaaaaatc
    74161 aaacgtgttt tttgctgata agctgtgatc tgtttgacaa cttcttcaaa ggataatcca
    74221 agtttgatca accgctcaag ctccagtacg agcaaatcca tctcgccacc tgctgataaa
    74281 gaatcgatta gatgaatatt gacattagga ttttcttcaa gaagttcatt tttagccagt
    74341 cgtgcactat tatgactgcc agataaggtc cctgtaattg tcatcacgat aacattatct
    74401 gcacctctat aggcctgcaa aaaggcttct gggcttggac agctagatgt cgttgcttta
    74461 gacgactggt acatagttgt catcatatta tcgatatcta atccatcatc atctctaaaa
    74521 atttctgtgc caatctgtag ggtcaaaggc acacgttcaa agcgcaactc tttggattgt
    74581 ctagtcaaac ttctaagatc acatcctgaa tctgttacaa ttttccaagt cattttttat
    74641 ccttcttttt ctctaatttg tgttcggtaa caaagaccag attattaagc cttcgctaag
    74701 atgtctaggc taatggtaat aactagtcat taaatcctat gttttattac tagccttttc
    74761 aatagttagt aaagtcatcc aatagagcta tacaaggagg taatgaggct cctgataact
    74821 aactttagtt gacaaattaa gacttttccc ataaaattat atcattatta agtcggtttt
    74881 tgctactgat aactcatcag atgtaacact tgaaaggtat ttgtgatgac tgataaagca
    74941 ctctcaaaaa gatcacttca aaacttaaca caatttaata aagaaacacg acgcatagca
    75001 cgtgaatcta tggaaatcgc cttactaaat cttctagaaa caaaaccttt aggtgatatt
    75061 acgatttcag aattggtgac gaaagcagga gtatctcgta acgcttttta tcgtaattat
    75121 acctctaaag aagccattat agaacaactg ttagtagggg ttatccgtcg tatttttcgt
    75181 ggactaaaac aatttgatat taaaactcag gcttatcaag cttggctcta tctttttact
    75241 gaagctaaaa aagaagctca gcttcttaaa atgattttca aacatcacct gcaccatctt
    75301 ctaacacgat tagtcactaa acgtctgaaa gcttatcaaa aattaaaaga caaaaaacaa
    75361 tcgcactata agcgcctttt ttggagcaat gctattgttt ctgtcttgac aaactggatt
    75421 tcagatgaca tgatcgttcc tgccgaagaa atggctgcta tgggcttgcc tctattaacg
    75481 taaaaaggtt ccttttggga acctttttac gttaattgtt agtctttttg agctacaagt
    75541 gcaaactgac ggatagcctg ggccacaccc gccatatcat tagtcaaagt gactttgtca
    75601 gctaatggct tgatagctgc tgaagcattt tccatagcaa ctcctaaacc agcataagtt
    75661 aacatctcaa tgtcattggg agcatcccca atagccatca cttggtcagc agttaaaccc
    75721 aaatcttcta ctaattcttt gagagccgat gccttgctga ctccctgagg gagaatttct
    75781 aaaatattat cttggctacg aacaacatga aaactctgac taagctgatt tctcaccgca
    75841 cgttcaaagg catctagcgc agctttttct cctaagtaca tggcttgaaa aatcaggcga
    75901 ggagtgtccg acagctctgc taaggagaca ggcttgacaa tggtaaatac caaatctcca
    75961 tcttcctgca caaggtctgg cacttcttct tcaagcacca aataatcgtt ttcctcagtt
    76021 aaagtcaggt aaatatctgg aaaactttgg cttagctctt ccagcaattc aatatctgaa
    76081 accttcaaca tttttgaatg gcgtaattgc cagtcaggac tactataagt actacagcca
    76141 ttattgataa tgaggaattc ctcttgtgtc aaacctaatt ggtcaaaata gggtcttgtc
    76201 cctgactgag gccggcctgt gcataagaca atttttaagc ctgactgagc tgcttcttgg
    76261 atggctgtga tattctcttt tggaatctgt ttgtcctggt ttaataaggt gccgtccaaa
    76321 tcaattgcaa ttagttgaat catcctatct ttcctctttc catttgattt tagggaggtt
    76381 ccatttttta cggttgccaa tcatgcgtaa agtcgtgagt aaaacaacca aggcataaca
    76441 ttcaatcgtt gaatctgcta gtttaaaatg caaaacaata gctgcaagaa tagaccaccc
    76501 agcatagatt tcactacgca aaacactagg ttttcgccct gccagaatat ctctgacaac
    76561 accaccgcct gcaccagtca acacagctgc tacaatgaca gcacttaaag gctggttaag
    76621 acggacagca tgcaaggctc cttggacact aaaagctgcc agaccaatgg catcagtcaa
    76681 aacagctgcc cgtacccaac ctctagccat tagcttagga aaaagcataa tcaaaaccat
    76741 agcaaagaaa gcgcaagtga attctggctt ttgcccccat aaggcctcta taggtaaacc
    76801 aattagggtg tttcgaatgg ctccgcctcc aaaggctgtc acgaaaccta aaataaaaat
    76861 ccctaaaata tcaaattctt cttccatggc aacaatagca ccagaaagag caaaggcaat
    76921 ggtcccgatg atatttaaaa tttcccacat atcaattgtc ataagctacc ctattgtctt
    76981 ttagtcttct tttagtttac cacgttttcc tttaaaaaat aagtagaaaa agataaaatg
    77041 taaggataaa aaagcaagga taaaacccat tttcatcctt gctacaaaag attcaaacaa
    77101 ttatccccat acttatctta tcacatcaat gagagctgct tgataggata aggttgtttt
    77161 agattttttc cgtccaaggg ctagcggtct cttcgagtac cctgtttaac tcgtcaatat
    77221 tttggaagcc ttcagtgcat agccactttc ttgcttcgtc ctctccttta gtaatataaa
    77281 ctggaacgga tcctgcccac gtggcacgcc cacacaaaac accactaaat tgagcacctg
    77341 ctgctgctgc aaagtataat gtctcttgaa aaagtttggc agatacgcct gcactcaaat
    77401 agatataagg gaggtggctg gcagcttctt ggtcttgaaa agctttaata gcctcagctt
    77461 gactgtaatg gacttcccct tcagtaaaac cttctacata agccatatta acaggaacct
    77521 ctacttttag cacatcaacg ccaaaacgct tatccgaaaa tactgacata gcaccgttaa
    77581 ccttatgtgg cttaagcttt gcgtatgccg cactgttgtt atctgatatt ctctcatcat
    77641 aactcaaaag ttcaagaaaa aaagggatgt cttcagctgt acattctgaa ccaatgcgtt
    77701 caatataagc ttgtttttgt aaattgattt gttcatctcc atcaacatca taatagagca
    77761 aaaatttaat agcatctgca cctgctgctt tcaaccgttt gaccgaccat tccactaagc
    77821 aatcgggtaa acggctagtg gttgtagcat cataacctgt tttttcgtaa gctaacagta
    77881 agcctgtctg attagctctt accttagtag ccagcaaccc atattctgga tctaataaaa
    77941 tagatgaagc ataaggcgtc aattcctcag aaacgagaac tttcaatgtt tctatctgtg
    78001 taactgtcgc ttctccttct tgatgtgctg ccatcatttg cttcagtgca cctcgttgat
    78061 caaaagctaa agctgatatg attccttgat ggctcacttt ttctaagtaa tgtcttttat
    78121 ttgctgtgat tgtcatgtga tacctctctt acttgaagtt gctgatataa ttgtttaaaa
    78181 gttgccatag tcatcaaatc ttgataatag tgagtagcta gtctcctagg cagactgcct
    78241 gagaagttaa gacatcaaac ggcttagcaa tagtactcat gtggctcaaa gagacttcgg
    78301 cttcgtccac atcactgtag ggaccagctt ccaaaatttt tgtctgcatg ccttcatgta
    78361 aaacagcaat acaatttctc gtttcccctt tgattttgaa aaattggtta gaaatgccct
    78421 gttcttgtaa ctgatgaatg ataaagtcac ccagcttacc accactaaat cctgttgcca
    78481 taactgacca gcttttgcta acattctggt cacatttagc tccttatcac cagctgtttt
    78541 tgccgttctg tcaacacaat taaccgtgtc catagccaga caatctaaag gataggaaat
    78601 agcgacagaa ggatttaaga taactgttaa actcatctct tcttcctaat cgtgatactc
    78661 accacgatcc catttttcca aaaattctgt aaaaaaatca ggatcttctt ggttggcatg
    78721 atgactttcc aagtgggcta ttttagcaat tagcttctta ttctcttcag tttctttgta
    78781 ttctgccttg ataaaagcat ctataatatc acacataaga agttcacccg tgattttacc
    78841 accaaagcca atcacattgg cattcaattc ttccttggca taaagcgctg ttgtcatatc
    78901 tcgaacaagg gctgaacgaa tacctggtac cttgttcacg gcattattaa tgccaactcc
    78961 agttccacaa atacaaacac ccaagtctgc ttgaccatta accacagctt cgccgacttt
    79021 ttttccaaaa atagggtaat gggttcttgt atggtcataa gtgccacagt caataacgtc
    79081 atagccttta gatttcaaaa aatcagaaac agccattttt tcgttggtga caatatggtc
    79141 acaaccaatc gcaattttca tcactttatc ctcctttagg ccattttatt gagcatgtca
    79201 acacgaattt gatgacgacc accatcgtag ggaccagtca caaaaccttt gacgatattc
    79261 ttcgctaatt ctggacctac aatctctgcc cctattgtga tcatgcgggc attgttgtga
    79321 ccgcgcgtca tgtaagcaga gcgttcatct gacacttcag cagcaaccat tccttttaat
    79381 tttgtggcta ccataaaggg acctgctccg taagcatcca ccataatgcc taaacgacct
    79441 tctgcttcat taacggcttt cgccaccgct aatgtgttat caataaaatc actgttaata
    79501 tcagtcacgt caataatgtc atagccttct tcttgaagaa aacttttgat caattctttt
    79561 aatgcatttc cgtgtgcatc tgcacctaaa ataatagcca tagcttttcc ttttctaacc
    79621 caaaacgctt gccaatctag agaaggggga catgattacc tgtccttaga tcaagatgat
    79681 tgccagtagt cttagtgtct tccattattt ctttcaagac aaagcacttg tgggttccca
    79741 cagagcgcct tgccttacat gagaaatact cttttcacgt tagggagtaa ggtagaaata
    79801 ccttactccc taatttttta gtcagtcacc tgacctgatt ttatttcatt gttttcgcat
    79861 actcagcgtt acgtgccttc atttggttag cataccaagc aaagagacct aggtaaatgg
    79921 ccacaaagat gattagcgtg atgattgagg caatctgacc tgttgtcgct tgaccaatca
    79981 cataaccaaa aattttttcc attggtcctt caagtgttga atgcgtaatc aaggaaccag
    80041 cgcttgtacc tgctggaaaa gcccctactt ttttagccaa ctctgtcgca aatggagcaa
    80101 tcatagttcc tgacaagagg aataatggca ataagaggga accaaaaata atcatgcgaa
    80161 tcaaacgacc acgtgtgacc acaagaagag ctggtgtcat ccccatagca ataattcctg
    80221 ccagtggtaa aatcccattg ccaacttttg ataggagaac ggcttcaatc aacatgattg
    80281 gggcaagaat attggcacag gcccagattt cagcacgacc agcaatgaag ggccagtcca
    80341 aaccgatatt gaaacgacgc ccatgcattc tagcattggc aaaattggta atcccttgtg
    80401 acaaaggctc aacagctgcg ataaaccaag agccaatcaa agagaaaagt tccaagcagg
    80461 cacccgcggt aaagcctagg ccaaaccaat ttttgataga ttcaacagtg aaatgaggat
    80521 ctcccataat cccaatcaca aaacctagag ccattccgat aaagaactta gagccccaga
    80581 agccaatttt tttgttcaat ttagcagcat caaagtcata tttatccagc cccggaaaga
    80641 ccttgtcaaa aatcttatct aagaccataa tgattggatt catcatgtag ttcatgtgag
    80701 ttgaagtcat tggtgattga ggccctgtcc caagaaggtc atcaaaggtc ggtttcatca
    80761 aatcagagtt aatgattttc agtaccccaa caagaataac tgccacagta gcaatcaaaa
    80821 gagacacaaa gactggtaaa tggttacgag ccgcatacca cataatcaat agacccgtaa
    80881 tggacaaatg ccaaatatca aaaatatcga cgtcaagggt gtccgttttt ttcatgacaa
    80941 tcatgacaat attaaccacc agcatcacca gcaagaaata aagggtgtaa ggggaacccc
    81001 aggtaattgt tgcaagcggt gcccaaccga catcaataat gtttaaactg atccctgtat
    81061 ttttaacaaa ggcctgtaaa gactctgaaa aagcccccgt caaaattcca ataatggctc
    81121 caatccctgt caaagcgatg gctaacttaa tcccaccttc cagtgccttt gtgaatttaa
    81181 ccccgaaaat catggctaaa cctgtcatga caatcagcat gaccacacct gatcccaact
    81241 gaataggaaa tcccagaatc ttgttaataa tgtctaaaaa aggttgcatc atcttgtctc
    81301 cttatgtttt tattaactca ctgcaaatga ttttctttaa tcacgcgctc taattcagca
    81361 aaaacaggct cactcatgat tgggatacga tagagaatcg gtcctgcttc tactatggga
    81421 atcggcatct caaatcccaa gtcagttttt gcaatcggcg taaaaatatc ataacgagac
    81481 accaattctt ctgtgatgtc tttgaccatc accgcatcac agtgaacatc gtaaccacgg
    81541 tcactcatct gagtttcaat cgcatcttta atttgatggc ttgagttaac ccctgcaccg
    81601 caggctgcta gaattttaat catgctgaaa cactcctttt tctattaaat agtttgaaat
    81661 agcttgttta tcatctttta gactggctag atagctaaga ttgcctttcg taataaagaa
    81721 ggtaatgaga ttggatagaa tcgtcgtttg accctcgttt tgactattga taataaagaa
    81781 gaaatccgtt accaaacagt cttcctctgg attaatcatg tgcttaaagg taagggcttg
    81841 actatttcta acatagacca cttgatcaac caagcaatac ttggtttctg tatgcggaat
    81901 agccgcatac aaaatatctg acccatcttt gaggtccact ttgagtcctg tcggaaatac
    81961 cgcctcacgc tccactaaag cctgatggta ctcttgcgtc acatacccaa ccttttccaa
    82021 gtggctagca acaagatcaa aaagctctgg ctgcgtcctt gcttcagtaa atagaatatt
    82081 aggaaacact ccctaccgcc tttctataag tatcaatttt taacaactgt catctcatca
    82141 tcaacaaatt ggtaaccgtt tacaaaatca ttatagtata accttcaaca taattcaaca
    82201 tttttacgca atattttttg ttctatatgt ttgtttttgt tttgtttatt ttgttttatt
    82261 gaaatatgaa ggtctatatg ctatgataaa cataagtaaa taaactatag aaaggagccc
    82321 cttagatgtt aaaaagagaa agacttctaa aaattaccga aatagtcaat gagcaaggta
    82381 ttgttactgt gaatgatatt attcagactt taaacgtttc tgatatgaca gttcgtagag
    82441 acttagatga actggaaaaa gccggcaaat tgatccgcat ccatggaggt gcacaaagca
    82501 ttaccatgcc taataaaaaa gagcggtcaa atattgaaaa acaaaccgtt caaacaaagg
    82561 aaaaatggga actagcttca tatgcgacac aactagtcaa tgatggtgaa acaatcttta
    82621 ttggtccagg aacaacttta gaatgtttcg ctgagcagtt aaaaaatcgt cagattcgca
    82681 ttgtgaccaa tagcctccct gtctttaaca tccttcagga cagcgaaacc attgacctga
    82741 ttcttatcgg tggtgaatac cgatctatta caggagcttt tgtagggtcc cttgccagtc
    82801 aaaatatctc atccttaaaa tttgccaagg cttttattag ctgtaatggt atttataaaa
    82861 acgatattgc aacttatagc gaaactgaag gagagattca aaagctagct tttaataatt
    82921 ctattgaaaa atacctcttg gtagataacc aaaaattcaa tgcctacgac ttcttcattt
    82981 tttaccattt aaacaacatt gatgctgttg ttacagattc gcaaataact gaggacgtta
    83041 tcgaacgtta tagtcagttc acgcaattat tagtagccca cgaaaacaag gagtaaccgt
    83101 ttcatcaaga atgggcagcc tgtcagtgca tcgtccttaa acaccttctg gcaaaagtga
    83161 tttgccccca gagaggtgtt tttgttttgc tcggaacaca cctgctaacg tcagagtctt
    83221 tatgagtgac cacaaaaaaa gaagcccaga ttaaaaaact ggaacctctt ttgagatgaa
    83281 gtaaggctac caaaataacc taagaccatt tatataattc aaatttggta tccttcaaag
    83341 cacgcttgat taggaacgtt aaaggacgtc ctgtcacctt agcctctcct ttttccaaat
    83401 ttacctggac cgattgcaca ccggggacag ctgataattt ttcagtgacc gttcttgcgc
    83461 aaccgtcaca tgtcattcct gtaacctgat aatgtttttc cattttgtat tctcctttaa
    83521 atggtttttc cttttaatcg cagggcattc aaaacaactg atactgaact aaaactcatg
    83581 gcaaaacctg ctaacatcgg gttcaatagt ggacctccaa aaagatgaag taagcccatg
    83641 gccactggaa tcatgaggac attgtaaatg aatgcccaaa ataaattttc cttgacaatt
    83701 ctcatagtca ctcgactcaa tgacatagct ttcaccaaat ccagcatatc aggtttcatc
    83761 agaatcacat ccgccgattc aatggcaata tctgtccctg accccatagc tatcccaatg
    83821 tctgctacag ccaatgccgg agcatcatta ataccatcac ctaccattgc aacttttctc
    83881 ccttgagagc ggaggtctgc tatcacgcct gctttttgat caggtaagac ttgactgatc
    83941 acatctgtaa tccccacttg agaggcaata gccttagcgg tagcatcgtg gtcacctgtt
    84001 agcatgatgg tgtgaattcc cagttgatgc aaagcttcga cggtagcttg actatcttct
    84061 ttgacagcgt cagcaatact gaaaagagct cgtagctgcc cctctttagc ataatataca
    84121 agggtttggc ctttctcaga agccttagca caaaccgact gaacacaaga taaatcgata
    84181 ccaagaattc ccattaaagc agcatttcca atcgccaaac gacgcccttc aagctgacca
    84241 gtaactccta ggccggttaa agactcaaac tcttccactg gtagactatc gtaaccagct
    84301 tcctgagcag cacgaacaat agcctcccct aaggggtgtt gagaataggc ctccaaggaa
    84361 gcagcttctt gcaagataag gtgatcatct cccgaaaaag ttaggagctt ttgaagactt
    84421 ggtttcccct ccgtaatcgt ccccgtttta tcaaaaacaa ccgtatctac ctgatgtgct
    84481 tgttctaaga tgtcaccacc tttaaaaaga ataccatttt cagctgcacg ccctgttcca
    84541 accataatcg ctgtcggcgt tgctaaacca agcgcacaag ggcaagcaat gactagaaca
    84601 gcgatggctg ttgtcaaact aaaacgaaga ctttcctgca tgaataccaa ccaaaacacc
    84661 cctgttaaca gagctaatac caaaaccacc ggaacaaaga cacctgagac tctatcagca
    84721 atagctgcaa taggtgcttt attttcttga gcattctcaa ctagttggat aatttgtgct
    84781 aacaaggtat catttccaag cttatctggt ttaatcgtga gggcgcctgg cccattcaag
    84841 ctgcccgcaa agacattatc tttttctccc ttttcaacag gcaaactttc cccggttaaa
    84901 aaggattcat ccaaactgct atgtccttcc acgataatac cgtcaataga aactttttca
    84961 cctggttgaa ccaggacaag gtcatcatag ctaacttctt ctaatggtaa caattgccat
    85021 tggctgtttc tccataccct cacaacagta gccttcaagg ataggagctt ttgaatagct
    85081 tgagaagtac ggcccttaga acgactttca aaatactttc ctagaccgat gagtgtcaaa
    85141 atcactacca ccgattcaaa ataaagggag tgcacaaagt gcgcccggcc cagactgatt
    85201 tcaaccactc cataaagact ataagcaaaa gcaaagctgg ttgctaaagc taccaaggag
    85261 tccatattag gatgtccctt aaacaaagct ttaaacccat tatggtaata atgacgattt
    85321 aatactaaga ctggaatcgt caagagtagc tgactaaagc tgtaaacgaa aggatagcga
    85381 tctggttgca gaaatggagg aagccataag cccaccatgt gacccatagc taggtataat
    85441 ataggaatgg tgaatagggc agaccacaag acctgagacc aaataacctt taggtcttcg
    85501 tcacgacgac ctgtttgcat gtgttttgca tgttcatcaa agacttgtgc accataacca
    85561 gcagctttca ccgcttgaat aactttggcc gtttctaaat cgtcatcttg ataagtaacc
    85621 gtgagcttct cagtcgctaa attcacaaca gcctgttcta cttcaggcaa ttgattgacc
    85681 gttttttcaa ttgttagagc acaagaggca caactcattc cctccactaa aaatatctct
    85741 ttagccatta atacgtctcc tttctctgac agtggcactg cccaggcaga caattacacg
    85801 gcacctcaag aactgcattt tcttttttga cttctagtag ctcttggaat gccccgattt
    85861 cctctaaggt catcggtaag tgataaagcc gttcaagaag tagacgcgtg tgttgccgct
    85921 gacaaatacc gtctaaaaca gtcgctagtg cttctttttg tagcaaagtc tcatccaaaa
    85981 gagcttgata aatataagct cttccttgcc gataagacgt taaaaaattt tttttaacta
    86041 gcctaccaat gagggtctta atagtggaat ctgaccattg atattttttc cttaaaatag
    86101 taataatatc gctactttta atatcaccac tggcccacac cacacgcatg acttcccatt
    86161 cagcagctga tatctgttgc ataacgtcac cttcattcac aatatattta cgtttgtaaa
    86221 ttaattataa cgaatttaac tacatttgta aataaataac ttttctcatt tttctatcct
    86281 tatattgaca aatgaatcgt ttttactata atattattgc aataaaaata acatttacat
    86341 taaggagata cccttgaaac atcctattcg aaaaacactt gtcaccttag gtctattact
    86401 gaccttatgc ctgccgactc cagttgcagc tagttctcgt tcttggaaga gctggtttat
    86461 cgagcaatat ttctggttaa aacgtgacaa gagttactat tctaaacaag atgacccaag
    86521 cttccaaaga taccttgatg cctgtcgtga acaatctgat aaaccttatc aactagatac
    86581 taatttagtc aatggtcccc ttgttcaaga aaatctttat ggcatgcagg tttactcttg
    86641 gaatgataat ggaaaacctg atcaaaaaac aattatttat cttgccggtg gttcttatct
    86701 taacaatcca acgacatacc atattaatat gttaaagaca ttatccacaa gtcttgacgc
    86761 taaaattgtt ttacccattt atcctaaagc cccacgttat acctataact atactatgcc
    86821 aaaattggtc aatctttacc aacactatta ccataaaaat cagaatgttt tccttatggg
    86881 agattcagca ggtggaggtt tagccttagg tctagctcat gccctacaca atgaatcagt
    86941 ccctcaacca aagcagctcg ttcttttatc accttggtta gatgttacta tgtcacaccc
    87001 agagattcca gaatacgaag atgctgatcc tattctatct tcttggggat taaaacgagt
    87061 gggagaattg tgggcctact ctgctgataa taccaaccat atttatgtca gtcctaaaaa
    87121 tggtccgatc acttatctac caccaattac tttatttact gggacacgag agatctttta
    87181 tcctgatatt cgcgattatg ccgcaaaact gaaagccgct aaccacaata ttacctttat
    87241 tacccaagaa ggcatgaacc acgtttaccc aatttatcct atcgaagagg caaaaacagc
    87301 tcaataccaa atcattgatg ccatcaacaa aactccttaa tgaggggaat aactcctacc
    87361 tgccaccagt taatctggtg ttttttttgt agtttgcacc acaaaataac aattaaaaag
    87421 agccctatca taatgataag gctctttctg tcataacatc cgcaccgcaa tacttaggat
    87481 ttgttgtcaa gatctcgtaa gagttgatca attttattac cataggcgat ggaattgtct
    87541 ttttcaaaca ccaaatctgg aattttgtac atggtcaatt gtttgccaag ttcacgttta
    87601 atcgttccag tcgctttttc aagccctgtt tgtgcttttt gattatcaga tgccaagtca
    87661 ctcataatag tgtaataaac tttagcaagt gacaagtcac cctgcatttg cacttctgta
    87721 atcgttactc cctgaacgcg tggatcacgc acttttttct gaagaatatc atttacttcg
    87781 cgcttgattt ccatcccaac gcggtcaata cgatgattag ccatagccat ttcctttcca
    87841 cattttaaaa caaaagctag gctgaaagcc cagcttatga cattgctacc tgttttgata
    87901 acgacaatta aagggaatct gagaattcca tgacgagact ggaaggaatg ccccaagtag
    87961 ctcatctggt agaaaaagtc attatttccg acagaggaaa aacgttacat ctcagacctt
    88021 cttagcccct attttctcac aatttcttcc ataatatagg cttcaatagt atcgtcaact
    88081 ttaagatcgt taaagttttc aatcatcaac ccaccttctt gagcattacc gacttcttta
    88141 acgtcatctt tgtaatgttt caagctggcc agtttaccat caaaaataac gacactatca
    88201 cggataacac gaacactcga atcacgtgtc accttaccgt tgattaccat aaagccacca
    88261 attgttccca ctttagaaac tttgaaggtt tcacggataa tggcttcacc aagaattttt
    88321 tcttggtaaa cagggtcaag tttccctttc atggcttctt ctacttcttc aatgacttta
    88381 tagataatac tatgaagacg aatttccaca tcatccgtat ctgcttgttg acgagcttgt
    88441 ggggtagggc gaacgttgaa accgataata acagcatttg atgcttcagc aagggtcaca
    88501 tcagactcat tgatagcacc tacagcagag tgaacgacat tgacacggac accttccact
    88561 tcaatcttta caagagatgc tgcaagggct tcaacagaac cttgaacgtc tgctttgatg
    88621 atgacattaa cagtcttgat ttctcctgct ttaagggtat caaagagatt atcaaggcta
    88681 acacgctgtg tattttgacg ttgtttgagg agggcacgtt ttgatcgctc ctcaccagct
    88741 gcacgcgcag ctttttcatc agcgtaaaca gcaaagtgat caccagccat tggtgtttcg
    88801 ttcaaaccag taatggaaac tggtgttgat ggctccgcag atttaacacg acgcccaagg
    88861 tcatttacca tggcacggac acgaccaaag gtattaccaa caacgattgg atcttgaaca
    88921 tgaagagttc cttgttggac aagaagcgta gcgatagcac ctttaccttt atctaagcgt
    88981 gcttcaatta cagtaccaat agcacgaacc gtcggatcag ctttcaattc ttccacttca
    89041 gcaaccaaaa ggactgtttc taatagttca tcaatatttt tattaaattt agcagatatc
    89101 tctacaaatt cgcactctcc gccccaagca gttgagatga taccatattc tgccaattct
    89161 gcgataacac gttctggatt agcacctggt ttatcaattt tgttgatagc aacaataatt
    89221 ggaacaccag cagcttttga gtgattgatc gcttcaatcg tttgtggcat aacaccatca
    89281 tcagctgcaa caatcaaaat ggtgatatcg gtaacggaag ctccacgtgc gcgcatactt
    89341 gtaaaggccg cgtgtccggg agtatccaag aaggtaattt tcttgccagc ttcttcaatc
    89401 tggtaagcac caatatgctg agtaattcct ccagcttctc ctgttgccac acgtgagtta
    89461 cgcaaagtat caagcaaagt tgtcttaccg tggtctacgt gtcccatgat agttacaaca
    89521 ggtgcgcgtt ctacaatatt ttcaggattg aggtaatttt catcctcaaa gaagcgctcg
    89581 atatcagcat catctacttc taccttagcc ttagcctcaa taccataatc taccatcaat
    89641 aattcgatag tgtcaccatc taaagattgg ttttgagttg ccataacacc catcataaac
    89701 agctttttaa caatttcagc gggttcgcgt ttgatacgtt ttgcgatttc ggcaactgtc
    89761 atgccttcag tatattcaaa ttcttttggc aattcatgga atttacgctc ggttactggt
    89821 tttggagcgg tgttggtatt cttaacattt ttgccttttt tggtcttttt atttttattc
    89881 cagttactat ttttttgatt tctcacttgg ttttgactat tccaactctt cttatttttc
    89941 ttttgtcctt cttgtgaatg atgagttaac tcacgattct tttcaggacg tgcttgtttt
    90001 ttacggcgat tatcagcagt agatttagca ctaatatttg atgactttaa tttagtttct
    90061 gcttcttcaa tagatttcaa tgctgcttca cgatggctca tctcctcagc ttgtgctttt
    90121 agagccgctt ctttagcttc ttgtcttgcc aactcagcta aacgcttagc ttcttgctgt
    90181 gcacgaaaac gtgtttcact ttggcgtgag tattcagcat tttgttcagc ttttaaggca
    90241 gcagcacgag ctttgaaatc aattttagga cttttcgatt gaggctcttg tcgtccttgc
    90301 tttttttggt ttgtgaatcg accattcttg tgattctcct tagcaaagga acggttacga
    90361 tcaccaacta gctgatgatt atcatgtcta ggtgatacat tcgatgcttt tcgctcaata
    90421 cgcttatcgt ttgtatcacc ttgagaacga tgggtaatcc tcttatctcc ttgttcgtta
    90481 gtttgatgat tattgggctg gcgataacct cctcgacgtt cttgagaacg atgagaagag
    90541 ccatttgctt gttttcgagc agcctgttcc tttgcacgag cctctctttc agctttaaaa
    90601 ttacgactct ttggcttaga gacctgtgtt ttctctacat gctcagaacc tgtttctttg
    90661 accactgtta cagagggttg agcaacttct ttgggtttga ctgtttgaga agctgtcaca
    90721 tcaggtttag aagcctttga aaaacttgaa ataatctttt tcgcatccgc ttcttcaaca
    90781 cttgatgcat ggcttttcac atctaatcct aagtatttag cgtgttcaac cacctcttta
    90841 ctacttttac caatttcctt ggcaatttca tgtaatcttt tctttgacaa tttgtgtcct
    90901 cctattcatc tattccataa gagtcctcat tttctttgaa aatccagcat ctgcaatggc
    90961 agcaaccttc cttggtttac ctagtgcagc acttaattcc agtgcattca acactgtgga
    91021 gacttctaca ttataataat tacttttatc tgtcactttt tttgtcacat taggaccagc
    91081 atcattggct aaaaatacta atattacctg ctggtgttga atagctttta ctactagttc
    91141 ttcacctgaa atcacttttc cagcccgttg agctagacca ataagactag ataatctttc
    91201 taaattagtc aagacctaac tctcttcttt tgattttgtg atcaacataa gcaatcaagt
    91261 catcgtaaaa actttctgga atgtccattg agaaactcct gttgaaaact tgttttttct
    91321 tggccattaa ggcctcttga ttgtctaatt tgatataagc accacgacca ttttgtttac
    91381 cagttggatc aatgaaaact tgaccatcct tagtttttac aatcctaaga agatctcgtt
    91441 tagcaataat ttcaccagaa acaagtgatt ttcgtaaagg tatttttttg actttagaca
    91501 tcaaacacct cttttcttat acttcctcgg cagtcataac atcgtcaaca actggctctt
    91561 ccacagctgt tgctgcttct ttttccgcct caagacgatc atattcgcta gctgatttga
    91621 tatcaatacg gtagccagtc aaatgtgccg ctaaacgaac attttggccg cgacgcccga
    91681 tagctaatga taatttgcta tcaggaacta ctaccgtagc acgtttaaga tcttcatcgt
    91741 caaaaagtac catgtctact tcagccggag caatggcatt gtagatgaac tcagctggat
    91801 catctaccca ttgaatcacg tcaatatttt cttcaactgg aatttcaagc cccgtcttag
    91861 catctacacg ttttggatgg aacttgctga tgaccttttt aatattactt ccaccacgtc
    91921 caacaattgt tccgatggca tcaacgttag gattatgact gcgcacagca accttggtgc
    91981 ggtcacctgc ttcacgagaa acactcatga tttcaacagt accatcaaag acttcaggaa
    92041 tttcttgctc cataatacgt ttgatgaatt ctggatggct acgactaaca aagacgttaa
    92101 ctcctttagg attattttca actttgtaga cataaacgtc aatacggtca tgtgatttga
    92161 aagtttcacc tggaatctgg tcttggtgag acaattgtgc ttctaaggaa ccaagattga
    92221 cataaataaa acgttgatca aaccgttcaa ctgttcctgt cataatttca ccttcatgct
    92281 ctttgtattc attgaacatc acttcacgca tttggcggcg catcttttcc ataatagtct
    92341 gtttagctga ttgagctgcg acacgtccaa attcattgac agattcttca aagcgaatct
    92401 tatcacccaa ttcataggca gaactgatag caagagcatc tttcaaacta atctcaagcc
    92461 ggctgtcaaa aacttcttca acaacctcac gaaccgtaaa tacttgaaaa tcagctgttt
    92521 tttcattaaa ttcaataaca catgattctg attgaccata gcgacgttta taggcagact
    92581 ttaatgattc tgtcactgcg tcaataatat ctgctttatc aatgtgtttt tcttcttcca
    92641 aaatacggaa ggcttctagc atttctttgc tcataatgtt atctaccttg cttgtaaagc
    92701 ttggcaaaaa tcctttctta aattaatacg atcaatagcc ccctaaaggc tcccttaatt
    92761 ccttttgttt agcttgtata aactctatag gtgttgtttc aaatttgctt aaatgttcct
    92821 aaaaaagttt agtgctttga aataaaagtt ataatttgac agccattctc accttagcaa
    92881 ctgcttgata tggtatattc acgatcttat gacgtgtttt atcaagataa tcaatggtca
    92941 acgtttcacc atcaaaggct aataagtctc cttgaaaaac tttcacctta tcaatagctt
    93001 gataaagact cacattgata taagagccaa ctgctgcttt taaactgtca gctgtcttga
    93061 gcggacgctc caaacctgga ctagagactt ctagcatata ttggtttgga aaaggatctg
    93121 gatcaatcgt atctaacagc ggactaataa tattcgtcaa gtcagatgta tcttccactg
    93181 tgattccacc ttccttatcg actaaaatac taaggatgta gtcactaccc attttgtcat
    93241 actcaacgtc tactaattca taaggtgcct taatctcagg cgttactgtc ttggttacga
    93301 tatcgataat agatgtattt gctattttga ttacctcctc tatttttatg ctcttctcta
    93361 agataattgg tccttgggaa tccacttaat acaaaagtgg cgagacatat cccaccacct
    93421 ttctgtatta tttaagccta ttataccata atttaagagg aatgcaagga tatgcacttt
    93481 gttttactca caaggagagg aggggattgc tggtagctat ctcaccgttt tcatcctttg
    93541 caagacactt aaacgttggt atttttaaaa tatagaaagg atagaaaaag atgaaaaaat
    93601 aaaaataaac gggtgattga cgggtaatgt tactccaatt ccatcaacac ttcttccact
    93661 ttttcatctg tcacaacttc tccattcttt actttctcat gtggcaacac ataatcaaag
    93721 atctgtccgt ttttgcgcac aatcgctact gtgtctcctg tgatataccc atggtcgatt
    93781 gcttgcttaa attcgtcgta tgttagcata gattacctcc ttatcttatt attcgtattt
    93841 tacaggaaat aatata
//
LOCUS       DAUGJR010000003        71566 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUGJR010000003 DAUGJR010000000
VERSION     DAUGJR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71566
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.003"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            77..2596
                     /gene="secA"
                     /locus_tag="VH800_000179"
     CDS             77..2596
                     /gene="secA"
                     /locus_tag="VH800_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEQ8361278.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
     gene            2712..3068
                     /locus_tag="VH800_000180"
     CDS             2712..3068
                     /locus_tag="VH800_000180"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEQ8361279.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLNYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            3065..4165
                     /locus_tag="VH800_000181"
     CDS             3065..4165
                     /locus_tag="VH800_000181"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEQ8361280.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            4252..5763
                     /locus_tag="VH800_000182"
     CDS             4252..5763
                     /locus_tag="VH800_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8361281.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAIGSSDNKA
                     EAENQVDDKSTDHSKSTDHSKPTDQPKPSPSKVDTAPASSLSKQLPEARTPIQSLSPY
                     VSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYD
                     STRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQ
                     ASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSG
                     KRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSY
                     AWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKVGYALSKTPKVGYAISFAPGQAGAD
                     GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN"
     gene            6252..10079
                     /gene="shr"
                     /locus_tag="VH800_000183"
     CDS             6252..10079
                     /gene="shr"
                     /locus_tag="VH800_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ8361282.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKIIVDNDVYEKSLEGERTFDINYQGIKINADLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKTVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     VEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            10276..11151
                     /locus_tag="VH800_000184"
     CDS             10276..11151
                     /locus_tag="VH800_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEQ8361283.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTNLVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDSQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            11135..12019
                     /gene="isdE"
                     /locus_tag="VH800_000185"
     CDS             11135..12019
                     /gene="isdE"
                     /locus_tag="VH800_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEQ8361284.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHP"
     gene            12021..13043
                     /locus_tag="VH800_000186"
     CDS             12021..13043
                     /locus_tag="VH800_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8361285.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            13040..13876
                     /locus_tag="VH800_000187"
     CDS             13040..13876
                     /locus_tag="VH800_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361286.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNGIRTQRRDRNK
                     NR"
     gene            13873..15636
                     /locus_tag="VH800_000188"
     CDS             13873..15636
                     /locus_tag="VH800_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEQ8361287.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            15629..17299
                     /locus_tag="VH800_000189"
     CDS             15629..17299
                     /locus_tag="VH800_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361288.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLTVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLIFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACVDHLFCVKNGSLKEVNKK"
     gene            17296..17889
                     /locus_tag="VH800_000190"
     CDS             17296..17889
                     /locus_tag="VH800_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEQ8361289.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSVFAHYLLKKHFIKSGLLS"
     gene            17886..18566
                     /locus_tag="VH800_000191"
     CDS             17886..18566
                     /locus_tag="VH800_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8361290.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWRFPEVWLLTLAVMCRFIPMIRQECCVIHRSLKIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            18503..19957
                     /locus_tag="VH800_000192"
     CDS             18503..19957
                     /locus_tag="VH800_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361291.1"
                     /translation="MERLGGADLDYCYHNHHDTAMISAEQLVFTYHDQKNPACQISTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQNLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAVGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            20332..22347
                     /gene="recG"
                     /locus_tag="VH800_000193"
     CDS             20332..22347
                     /gene="recG"
                     /locus_tag="VH800_000193"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEQ8361292.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENKSETNGLPILYSKRAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSIIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     YKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGISEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAQNIRKKEVYD"
     gene            22640..23542
                     /locus_tag="VH800_000194"
     CDS             22640..23542
                     /locus_tag="VH800_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8361293.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDCSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            23555..24259
                     /locus_tag="VH800_000195"
     CDS             23555..24259
                     /locus_tag="VH800_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361294.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(24608..25573)
                     /locus_tag="VH800_000196"
     CDS             complement(24608..25573)
                     /locus_tag="VH800_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEQ8361295.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVILVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            25645..27033
                     /locus_tag="VH800_000197"
     CDS             25645..27033
                     /locus_tag="VH800_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8361296.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDIEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            complement(27156..27608)
                     /locus_tag="VH800_000198"
     CDS             complement(27156..27608)
                     /locus_tag="VH800_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEQ8361297.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDNFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            27839..29053
                     /locus_tag="VH800_000199"
     CDS             27839..29053
                     /locus_tag="VH800_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8361298.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            29271..30053
                     /gene="codY"
                     /locus_tag="VH800_000200"
     CDS             29271..30053
                     /gene="codY"
                     /locus_tag="VH800_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEQ8361299.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            30200..30754
                     /locus_tag="VH800_000201"
     CDS             30200..30754
                     /locus_tag="VH800_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEQ8361300.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            31269..31517
                     /locus_tag="VH800_000202"
     CDS             31269..31517
                     /locus_tag="VH800_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8361301.1"
                     /translation="MIRSRSRPLIRKGLAVSLARSVKPELKLGICGEHGGDPASIAFC
                     HSQGLTYVSCSPFRVPLTRLAAAQAAIKASGHSLTQDK"
     gene            31749..32051
                     /gene="gatC"
                     /locus_tag="VH800_000203"
     CDS             31749..32051
                     /gene="gatC"
                     /locus_tag="VH800_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEQ8361302.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            32051..33517
                     /gene="gatA"
                     /locus_tag="VH800_000204"
     CDS             32051..33517
                     /gene="gatA"
                     /locus_tag="VH800_000204"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEQ8361303.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQATLEDIKSREEAVGSFI
                     TVSEEVALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKEILTTAASKMLYNYEPIFN
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLASVKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            33517..34956
                     /gene="gatB"
                     /locus_tag="VH800_000205"
     CDS             33517..34956
                     /gene="gatB"
                     /locus_tag="VH800_000205"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEQ8361304.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            34953..35168
                     /locus_tag="VH800_000206"
     CDS             34953..35168
                     /locus_tag="VH800_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361305.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTAYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNYHVCLHYY"
     gene            35387..35626
                     /locus_tag="VH800_000207"
     CDS             35387..35626
                     /locus_tag="VH800_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8361306.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            36017..36724
                     /locus_tag="VH800_000208"
     CDS             36017..36724
                     /locus_tag="VH800_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8361307.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            36714..37457
                     /locus_tag="VH800_000209"
     CDS             36714..37457
                     /locus_tag="VH800_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEQ8361308.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            37454..38023
                     /locus_tag="VH800_000210"
     CDS             37454..38023
                     /locus_tag="VH800_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8361309.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQVA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            38158..39192
                     /gene="hrcA"
                     /locus_tag="VH800_000211"
     CDS             38158..39192
                     /gene="hrcA"
                     /locus_tag="VH800_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEQ8361310.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            39195..39767
                     /gene="grpE"
                     /locus_tag="VH800_000212"
     CDS             39195..39767
                     /gene="grpE"
                     /locus_tag="VH800_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEQ8361311.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            39948..41774
                     /gene="dnaK"
                     /locus_tag="VH800_000213"
     CDS             39948..41774
                     /gene="dnaK"
                     /locus_tag="VH800_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEQ8361312.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            42055..43191
                     /gene="dnaJ"
                     /locus_tag="VH800_000214"
     CDS             42055..43191
                     /gene="dnaJ"
                     /locus_tag="VH800_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEQ8361313.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            43411..44202
                     /locus_tag="VH800_000215"
     CDS             43411..44202
                     /locus_tag="VH800_000215"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEQ8361314.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            44279..44713
                     /locus_tag="VH800_000216"
     CDS             44279..44713
                     /locus_tag="VH800_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8361315.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            44714..45688
                     /locus_tag="VH800_000217"
     CDS             44714..45688
                     /locus_tag="VH800_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEQ8361316.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVRI"
     gene            45749..45973
                     /locus_tag="VH800_000218"
     CDS             45749..45973
                     /locus_tag="VH800_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8361317.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            46175..47146
                     /gene="fabK"
                     /locus_tag="VH800_000219"
     CDS             46175..47146
                     /gene="fabK"
                     /locus_tag="VH800_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEQ8361318.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            47171..48109
                     /gene="fabD"
                     /locus_tag="VH800_000220"
     CDS             47171..48109
                     /gene="fabD"
                     /locus_tag="VH800_000220"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEQ8361319.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            48099..48833
                     /gene="fabG"
                     /locus_tag="VH800_000221"
     CDS             48099..48833
                     /gene="fabG"
                     /locus_tag="VH800_000221"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEQ8361320.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            48848..50080
                     /gene="fabF"
                     /locus_tag="VH800_000222"
     CDS             48848..50080
                     /gene="fabF"
                     /locus_tag="VH800_000222"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEQ8361321.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMVDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            50082..50582
                     /locus_tag="VH800_000223"
     CDS             50082..50582
                     /locus_tag="VH800_000223"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEQ8361322.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            50579..51001
                     /gene="fabZ"
                     /locus_tag="VH800_000224"
     CDS             50579..51001
                     /gene="fabZ"
                     /locus_tag="VH800_000224"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEQ8361323.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            51033..52397
                     /locus_tag="VH800_000225"
     CDS             51033..52397
                     /locus_tag="VH800_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEQ8361324.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            52406..53272
                     /locus_tag="VH800_000226"
     CDS             52406..53272
                     /locus_tag="VH800_000226"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEQ8361325.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKEQKIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            53269..54039
                     /locus_tag="VH800_000227"
     CDS             53269..54039
                     /locus_tag="VH800_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEQ8361326.1"
                     /translation="MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYKMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(54261..55538)
                     /gene="serS"
                     /locus_tag="VH800_000228"
     CDS             complement(54261..55538)
                     /gene="serS"
                     /locus_tag="VH800_000228"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEQ8361327.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(55930..56289)
                     /locus_tag="VH800_000229"
     CDS             complement(55930..56289)
                     /locus_tag="VH800_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEQ8361328.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            complement(56403..57314)
                     /locus_tag="VH800_000230"
     CDS             complement(56403..57314)
                     /locus_tag="VH800_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8361329.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTIRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            complement(57331..58140)
                     /locus_tag="VH800_000231"
     CDS             complement(57331..58140)
                     /locus_tag="VH800_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEQ8361330.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            complement(58229..59221)
                     /gene="manX"
                     /locus_tag="VH800_000232"
     CDS             complement(58229..59221)
                     /gene="manX"
                     /locus_tag="VH800_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEQ8361331.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            complement(59573..60385)
                     /locus_tag="VH800_000233"
     CDS             complement(59573..60385)
                     /locus_tag="VH800_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8361332.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALGYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRACFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            60649..62109
                     /locus_tag="VH800_000234"
     CDS             60649..62109
                     /locus_tag="VH800_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEQ8361333.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSGVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIIVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            62263..62724
                     /gene="tsaE"
                     /locus_tag="VH800_000235"
     CDS             62263..62724
                     /gene="tsaE"
                     /locus_tag="VH800_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEQ8361334.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHGSAKSRY"
     gene            62699..63223
                     /locus_tag="VH800_000236"
     CDS             62699..63223
                     /locus_tag="VH800_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8361335.1"
                     /translation="MVQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            63232..64506
                     /locus_tag="VH800_000237"
     CDS             63232..64506
                     /locus_tag="VH800_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8361336.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSNKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVNQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGQSASTDQDSTASSHRPA
                     TPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(64617..64973)
                     /locus_tag="VH800_000238"
     CDS             complement(64617..64973)
                     /locus_tag="VH800_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ8361337.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(64970..65389)
                     /locus_tag="VH800_000239"
     CDS             complement(64970..65389)
                     /locus_tag="VH800_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8361338.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            65461..66186
                     /locus_tag="VH800_000240"
     CDS             65461..66186
                     /locus_tag="VH800_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361339.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            66189..67223
                     /locus_tag="VH800_000241"
     CDS             66189..67223
                     /locus_tag="VH800_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361340.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNMLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            67287..68078
                     /locus_tag="VH800_000242"
     CDS             67287..68078
                     /locus_tag="VH800_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEQ8361341.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            68078..68713
                     /gene="trmB"
                     /locus_tag="VH800_000243"
     CDS             68078..68713
                     /gene="trmB"
                     /locus_tag="VH800_000243"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEQ8361342.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            68778..68864
                     /locus_tag="VH800_000244"
     tRNA            68778..68864
                     /locus_tag="VH800_000244"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:68812..68814,aa:Ser,seq:gga)
     gene            complement(68911..69990)
                     /locus_tag="VH800_000245"
     CDS             complement(68911..69990)
                     /locus_tag="VH800_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8361343.1"
                     /translation="MAFYRKLGSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AEIDLNTLTADLLDITVLDYNRRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGAKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADGAIVRSQKP
                     AKEESEKFMEESEYLAFIKVAKSKVKYPSYLTTYIIAVTGLRFAEVQGLTWKDIDFEN
                     GYIDINKTFDYSISQNFGPTKNEQSIRKVPIDKNSLEILRNFKSDYYQDNKLGRVCFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKFDG"
     gene            complement(70107..70658)
                     /locus_tag="VH800_000246"
     CDS             complement(70107..70658)
                     /locus_tag="VH800_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361344.1"
                     /translation="MDIAKLKEFAITAAGKAKDGAIKANELRKKASQESKIILPPALN
                     LELGAQTAIRKTIDGKYYIGFYSETPELYEFVSLQFDGSRIIEKTVTKGKTTQKGRSS
                     SVLGGAAIGKVLAPGVGTIIGGMAGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEVKTLKTKLTQAQYVSVNNFFK"
     gene            complement(70669..71052)
                     /locus_tag="VH800_000247"
     CDS             complement(70669..71052)
                     /locus_tag="VH800_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEQ8361345.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMIKEELEFLIS"
     gene            complement(71066..71467)
                     /locus_tag="VH800_000248"
     CDS             complement(71066..71467)
                     /locus_tag="VH800_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361346.1"
                     /translation="MLFYRYFLSSHRKADKSMFSTFERIKELAKSRGISLGLLEEKLG
                     LSRNSIYTIKNKKPSAERLQLIADYFHVSTDYLLGRTDNPKIAQDGHASVAIDLKKDA
                     EETFFFDGHELNDEDIDLITSILETRIKNRK"
BASE COUNT        21999 a        12410 c        15040 g        22117 t
ORIGIN      
        1 aactttacca acctttcttg aactgcctgc atatttatgt taaaatgaaa tgattagatg
       61 atcgaaagga aagagaatgg ccaatattct acgcaaagtt atcgaaaatg acaaaggcga
      121 actaagaaaa ttagaaaaaa ttgcaaaaaa agtagaatcc tacgcagacc aaatggcgtc
      181 attgtcggat agagatctac aaggaaaaac acttgaattt aaagaacgct atcaaaaagg
      241 tgagaccctc gaacaactat tacctgaagc tttcgcagtt gttcgtgaag cagcaaaacg
      301 tgtgttgggc ttgttccctt atcgtgttca aattatggga ggaattgttc ttcataacgg
      361 ggatgtccct gaaatgcgta ctggtgaagg aaaaactctt acagccacca tgccagttta
      421 tctcaatgct attgctggtg agggtgttca cgttattact gttaatgagt atctttcaac
      481 gcgtgacgct accgaaatgg gtgaagtgta tagctggtta ggtctttcag ttgggatcaa
      541 cctagctgct aagtctcctg ctgaaaaacg tgaagcttat aattgtgata ttacttattc
      601 aaccaactct gaagtcggtt ttgattacct tcgtgacaac atggttgttc gccaggaaga
      661 catggtacaa cgcccactca attttgcctt ggttgatgaa gtggactcag tcttaattga
      721 cgaggcaagg acacctttaa ttgtttctgg tgctgttagc tctgaaacca atcaattgta
      781 tattcgtgct gacatgtttg taaaaactct gacgtcagtg gattatgtta ttgatgtgcc
      841 cactaaaacg attggattaa gcgattcagg tattgataaa gctgagagtt actttaactt
      901 gagcaatctt tacgatattg aaaatgtagc cttgactcac tttatagaca acgcccttcg
      961 tgcaaactat attatgttgt tagatatcga ttatgtggtc agcgaagatg gtgagattct
     1021 tattgttgac caatttacag gtcgtacgat ggaagggcgt cgcttctcag acggcttgca
     1081 ccaagctatt gaggcaaaag aaggcgttcg tattcaggaa gaatcaaaaa ccagcgcctc
     1141 aatcacttac caaaatatgt ttcgtatgta caaaaaattg gcaggtatga ctggtactgc
     1201 gaagaccgag gaagaagaat ttcgcgaagt ttataacatg cgtattattc caattccaac
     1261 caatcgtcca attgcccgta ttgatcacac tgatttgctt tacccgacct tagaatcaaa
     1321 gtttagagca gttgtggaag acgttaaaac gcgtcatgca aaaggacaac ctatccttgt
     1381 aggtacggtt gctgttgaaa ctagtgattt gatttcacgc aagctggttg aagcagggat
     1441 tcctcatgag gttttgaatg ctaaaaatca ctttaaagaa gctcaaatca ttatgaatgc
     1501 tgggcaacgt ggtgctgtta caatcgcaac taacatggct ggtcgtggta ctgatatcaa
     1561 gcttggtgaa ggtgttcgtg aacttggtgg gttatgtgtc attggtacag agcgtcatga
     1621 aagccgtcgt atcgataacc agcttcgtgg acgttcaggt cgtcaaggag atccaggtga
     1681 atcccaattc tatctttcat tagaagatga tttgatgaga cgtttcggct ctgatcgtat
     1741 aaaagccttt ttggatcgga tgaaattaga tgaagaagac actgttatta aatcaggtat
     1801 gttagggcgt caagtggaat ctgctcaaaa acgggttgaa ggaaataact atgatacccg
     1861 taaacaggtc ttacaatatg atgatgtgat gcgtgaacag cgtgaaatta tctatgctaa
     1921 ccgtcgtgat gtcataactg ctaatcgaga tcttggccca gaaattaaag ctatgatcaa
     1981 gcgtactatc gaccgtgctg tagatgctca tgcacgtagc aatcgtaaag atgctataga
     2041 tgctattgta acttttgcta ggacctcgct ggtaccagaa gagtctatta gtgctaaaga
     2101 gttacgtggt ttaaaagatg atcaaatcaa agagaagctt tatcaaagag cgcttgctat
     2161 ctacgaccag caactatcaa aacttcgtga tcaagaagct attattgaat tccaaaaagt
     2221 actcattttg atgattgtgg ataacaaatg gactgaacac attgatgcct tagatcaact
     2281 tcgtaatgct gttggacttc gggggtatgc tcaaaataac cctgtggtgg aataccaagc
     2341 agaaggtttc aagatgttcc aagatatgat tggtgctatc gagtttgatg taacacgtac
     2401 catgatgaaa gcacaaattc acgaacaaga acgtgaacgt gcaagtcaac gtgccacaac
     2461 agcagcacct caaaacatcc aatcgcagca gtcagctaac accgatgatt tacccaaagt
     2521 ggagcgtaac gaagcttgtc catgtggttc aggcaaaaaa ttcaaaaatt gtcacggtcg
     2581 taaatccttc tcataagaac gagacacaac aggacaaagt taggtatata gaaagaagct
     2641 gagaataatt ctcagcttct cactgtttaa atcttctaac attaagatga aataaggttt
     2701 ggtggaaagt aatgattgtt ggacatggaa tagacttaca agagatttca gctattgaaa
     2761 aagtttatca aagaaatcct cgctttgctc aaaaaatttt aactgagcag gaattggcta
     2821 tttttgagag ttttccttac aaacgtcgac tcaactattt ggcaggacgc tggtcaggta
     2881 aggaagcttt tgctaaggct atagggacag gtattgggcg gttaaccttt caagatattg
     2941 agattttaaa tgatgttaga ggatgtccca ttctgacaaa atctccgttt aaaggaaata
     3001 gttttattag catctcacat agtggcaatt atgtacaggc tagtgttatt ttggaggata
     3061 aaaaatgatt tcaagtttcc atcgcccaac agttgcaagg gtcaacttac aagctattaa
     3121 ggagaatgtt gccagtgttc aaaagcatat tccactaggg gtaaaaacgt atgcagttgt
     3181 caaggctgat gcttatggtc atggtgctgt ccaggtgtca aaagcactcc tacctcaagt
     3241 ggatgggtac tgtgtgtcaa atcttgatga ggctttgcaa ttacgtcaag caggtattga
     3301 taaagagatt ttaattcttg gggttttgct gccaaatgaa ttagagttag cagttgctaa
     3361 tgctattact gttacaatcg ctagtttaga ctggatagct ttagctagac tggagaaaaa
     3421 agaatgtcaa ggcttaaaag ttcatgtaaa agttgattct ggtatggggc ggatcgggct
     3481 tcgttcttca aaagaagtca atttattgat tgatagtcta aaagagttgg gtgctgatgt
     3541 agaaggtatt ttcactcatt ttgccacagc tgatgaggca gatgatacta aatttaacca
     3601 gcagttacag ttttttaaaa agctgatagc tggacttgag gataagcctc gtttagtaca
     3661 tgctagtaat tcagccacaa gtatctggca tagtgatacc atttttaatg ctgttcgttt
     3721 aggaattgtc agttatggtt tgaatccaag tggttctgat ctaagcttac cgtttccact
     3781 gcaagaggct ttatctctag aatctagctt agtgcatgtc aagatgattt cagctggtga
     3841 tacagtcggt tatggagcta cttatactgc caaaaagtct gaatatgtag ggactgtccc
     3901 aatcggttat gcagatggct ggaccaggaa catgcaaggc ttttcggtgt tagttgatgg
     3961 acaattctgc gaaattatag ggcgtgtatc gatggatcaa ctgaccatac gacttcccaa
     4021 agcatatcct ttaggaacaa aagtcacttt gattggcagc aatcagcaaa aaaatatttc
     4081 tacaacagat atcgcaaatt accgtaatac aatcaattat gaagttctat gccttttaag
     4141 tgaccgtatt cctcggatat attaagaaaa tcatgtaaaa ataattgcat tgtgcttatc
     4201 tttaatgtta taataaagtg aggacattag aaagaagtga ctaattaata tatgaataaa
     4261 aacaaactat taagagttgc catgctacta agtctcttag ccccgacagc agaaagcatg
     4321 acagtgctgg ctcaagatgt aatgcttgag acgcataaag caactacaaa tgaaaccagt
     4381 gattcttctt caaaagagga aaataataaa aatgcagcac ctacaacatc agataaaact
     4441 gaccaaggtc cccttgatgc ttctgcagaa acaaactcta atagtcttgt taacgcggat
     4501 gataaaaaaa gaagcgattc tagtcagtct gctataggct cttcggacaa caaggcagaa
     4561 gcagaaaacc aggtagatga taaatcaact gatcattcga aatcaactga tcattcgaaa
     4621 ccaactgacc agcccaaacc atcaccatct aaagttgata cggcacctgc ttcttcattg
     4681 tcgaaacaac tgccagaggc aagaactcct attcagtcgt tgtcccctta cgtatcagat
     4741 ttagatttga gtgagataga tatcccttct gtcaacacat acgcggcata tgtagagcat
     4801 tggagtggta aaaatgccta tacccaccat cttttatctc gccgttatgg tattaaagct
     4861 gaccagattg atagttactt aaaatcaaca ggcattgcct atgacagcac acgtattaat
     4921 ggtgagaagc tattgcaatg ggaaaagaaa agtgggctgg atgttcgagc tatcgtagct
     4981 attgcgatgt ctgagagttc tttaggaact caagggattg caactttgct tggagctaat
     5041 atgtttggct atgcagcttt tgatctagat ccgactcaag caagtaagtt taatgatgat
     5101 agtgctattg tcaaaatgac acaagacacc attattaaaa acaaaaatag caattttgca
     5161 cttcaagatt taaaagcggc taagttttca cgaggtcaat taaactttgc aagtgacggg
     5221 ggtgtttatt ttactgatac tactggtagt ggtaaacgtc gcgcacaaat tatggaagac
     5281 ctggataagt ggattgatga ccatggtggc acaccagcca ttccagccga attgaaagtg
     5341 cagtcatcag ctagttttgc atctgtgcca gcaggttata agctctctaa gagttatgat
     5401 gtcttgggtt atcaagcttc gagttatgct tggggacaat gcacttggta tgtgtataat
     5461 cgcgccaaag aattgggtta ccaatttgat ccttttatgg gaaatggtgg agattggaag
     5521 tataaagtag ggtatgccct ttcaaagact ccaaaagtag gttatgctat ttcatttgca
     5581 ccagggcaag cgggcgctga tggcacttat ggccacgtat caattgtaga agatgttaga
     5641 aaagatgggt ctattcttat ttcagagtct aactgtatcg gcttaggtaa gatttcttat
     5701 cgtaccttta cagctcagca ggctgaacag ctaacatatg ttattggcaa gagtaaaaac
     5761 taataactaa tgacttttct taaggcttaa ttttcttagc gggagttagg ccttttaaac
     5821 tgttggtgta acacgataaa gtttcaagtc aataaatgat tttgagacaa tagcacgatt
     5881 agggctattg tcttttttta ttgtgatgaa tatgcagtag tgacatctca tgttgtctcc
     5941 taacacaatt atggagctta taacgtgtta catgttttgt gaatgaagta atgattgaat
     6001 cagctctagt attaactatc ctaaggctag ctttatctca gtaatattat tgtagaggaa
     6061 ttcttttatc agagatatcc tcattatcaa tccaggatta ttactagtgt cttagctcac
     6121 atagtggagc tatttaacag acaattggac cattggaaac aatcttgaca aaataatcac
     6181 aaagtgatag attaagttca gttaatataa aagttagctt attcataaaa tttttagaaa
     6241 gttgattgaa aatgaaaaaa atcagcaaat gtgcgtttgt ggcaatatct gcccttgttc
     6301 tcattcaggc tactcaaact gtaaaatcac aagagccttt agttcagtca caactcgtga
     6361 caacagtagc tttaactcag gataatcgac ttttagttga agagataggc ccttacgcta
     6421 gtcaatcagc tggaaaagag tattataaac atattgaaaa gattattgtt gataatgatg
     6481 tctatgaaaa aagcctggag ggcgagcgaa cctttgatat taactaccaa gggattaaga
     6541 tcaatgctga ccttattaaa gacggtaagc atgaattgac tattgttaat aaaaaagatg
     6601 gtgatatcct aattaccttt attaaaaagg gcgataaagt gacctttatt tcagctcaaa
     6661 aattaggaac aacagatcat caggattcat taaaaaaaga tgtgctcagt gataaaacag
     6721 tgccacaaaa ccaaggcaca caaaaagttg ttaaatctgg gaaaaatact gctaacttgt
     6781 cattaataac aaaattgagt caagaagatg gtgcaatttt atttccagaa attgatcgtt
     6841 attctgataa caaacagata aaagcattga ctcagcaaat cacaaaggtt acagtcaatg
     6901 gtacagttta taaagatctt atttcagatt ctgtaaaaga tactaatggc tgggtctcga
     6961 atatgacagg gcttcatctt ggaacaaaag ctttcaaaga tggagaaaat acaatcgtga
     7021 tatcctcaaa aggatttgaa gacgttacta ttaccgttac caagaaagat ggtcaaatcc
     7081 attttgtatc tgccaaacaa aaacaacatg tgactgctga agacagacaa tcaacaaagt
     7141 tggatgtcac cactttggaa aaagctatca aagaagcgga tgcgattatt gctaaagaaa
     7201 gcaacaaaga cgcggtcaaa gatctggctg agaaacttca agtcatcaag gattcttaca
     7261 aagaaatcaa agatagtaag ctactcgccg atactcatcg actgttaaaa gataccatcg
     7321 agtcttatca agcaggtgag gtttctatta acaatctcac agaaggaacc tatacgctaa
     7381 actttaaagc taataaagaa aactcagaag agtcctccat gcttcaaggt gcttttgata
     7441 aaagagccaa attagtggtt aaagcagatg gtacaatgga aatttccatg cttaatactg
     7501 ctttgggaca atttttgatt gacttttcta ttgaaagcaa agggacctac ccagcagcag
     7561 tgcgtaaaca agttggccaa aaagatatca atggtagcta tattcgaagc gaatttacca
     7621 tgcctattga tgatttggat aaattacaca aaggtgctgt tttggtatca gccatgggag
     7681 gtcaagaaag tgatttaaac cactatgaca aatacaccaa acttgacatg acctttagta
     7741 agaccgttac caaaggctgg agtggttatc aggtagaaac tgatgataaa gaaaaagggg
     7801 ttgggactga acgtcttgaa aaagttttag ttaaacttgg caaagattta gacggcgatg
     7861 gtaaattatc aaaaacggaa ttagaacaga ttcgaggcga gttgcgtcta gaccattacg
     7921 agttaactga tatttcttta ttgaaacatg ctaaaaatat tacagaacta catctggatg
     7981 gaaaccaaat tacggaaatt ccaaaagagt tatttagtca aatgaagcaa cttcgatttc
     8041 ttaacttaag aagtaatcat ttaacttatc tagacaaaga tacatttaaa agcaatgctc
     8101 aattaagaga actctactta tcaagtaact ttattcactc tcttgaagga ggactattcc
     8161 agtcgcttca tcacctggag caacttgatc tttccaagaa tcgtattggc cgactttgtg
     8221 ataacccatt tgaaggattg tctcgtctga cttcattagg tttcgcagaa aatagtcttg
     8281 aggagatacc tgaaaaagcg ctagagcctc taacatcact taattttatc gacttatctc
     8341 aaaataattt agcactactg ccaaaaacaa tagaaaaatt gcgcgcctta agcactattg
     8401 tggcaagtag aaatcatatt actcgtattg ataatatttc atttaaaaat cttcctaaat
     8461 tatctgtact cgatttatca actaatgaaa tttcaaatct tccaaatggt atatttaaac
     8521 agaataacca attaacaaaa cttgattttt tcaataactt gcttactcag gttgaagaat
     8581 cagtatttcc agatgttgaa acgcttaatt tagatgtgaa gttcaatcag ataaaaagtg
     8641 tgagtccaaa agtaagagct cttatcggac aacacaaact gactccacaa aaacatattg
     8701 caaaacttga agcttcctta gatggcgaaa aaataaaata tcatcaagct ttcagtcttt
     8761 tagatttgta ttattgggag caaaaaacaa attctgccat tgataaagaa ctagtgtctg
     8821 ttgaagaata tcaacaattg ttacaagaaa aaggttcaga tacggtttct ttacttaatg
     8881 atatgcaagt cgattggagt attgtgattc agttgcaaaa aaaagcttcc aatggacagt
     8941 atgtgacggt tgacgaaaag cttctctcaa atgatccgaa agatgactta acgggagagt
     9001 tttctttaaa agatccaggt acatatcgga ttcgcaaagc tttaataaca aagaaatttg
     9061 ctactcaaaa agaacatatc tatttgacat ctaatgatat ccttgtggcg aaaggaccac
     9121 attcacatca gaaagattta gttgagaacg gccttagagc attaaatcaa aaacaattgc
     9181 gtgatggtat ttactattta aatgccagca tgttaaaaac tgacttagca tctgagtcca
     9241 tgtcaaacaa ggctattaat catcgagtga ctttggtagt taaaaaaggt gtttcctatt
     9301 tagaagttga gtttagaggt ataaaggttg gtaaaatgtt aggctacctt ggtgaattga
     9361 gctatttcgt agatggttac caaagagatt tagctggtaa accagttggt cgaacaaaaa
     9421 aggcagaggt tgtgtcttat ttcacggatg taactggcct accattggca gatcgttatg
     9481 gaaaaaacta tccaaaagtg ctgcgtatga aattgattga acaagcgaag aaagacggac
     9541 ttgtgccatt acaggtcttt gtgcctatca tggatgccat ttcaaaaggg tctggccttc
     9601 aaaccgtttt tatgcgttta gactgggcaa gccttacaac agagaaggca aaggttgtca
     9661 aagaaactaa taatccacaa gaaaatagcc atctaacttc aacagatcag ttgaaaggac
     9721 ctcaaaatcg tcaacaagaa aaaacaccta caagtcctcc ttcagcagct actggtattg
     9781 ctaacttaac tgatctcctg gctaaaaaag caaccggcca atcaactcaa gaaacttcta
     9841 agacagatga tactgataag gcagagaaat tgaagcagtt agtgcgtgac catcaaacat
     9901 caattgaagg taaaacagca aaagatacta agactaaaaa atctgataag aaacatcgtt
     9961 ccaatcaaca atcaaatggt gaagaaagta gctctcgtta tcacttaatt gcaggtctat
    10021 ctagctttat gatcgtagct ctgggattca ttattggtcg aaagacatta tttaaataag
    10081 aaacttagta ccaagtgaaa taacaaaaaa gctagtcagc aagagctaaa aacataccta
    10141 tttccgacag gactcctgat acaggttgaa gtagtcgcaa gataggtgtg tttttcacat
    10201 ttggagatgt tataaaatgg gattcattta aaaaatgaaa taagatgttt aagaaaagat
    10261 agacaagagg agcatatgac aaaggtagta ataaagcaat tgttgcaggt aatagtagtg
    10321 ttcatgataa gtttatcgac aatgacaaat cttgtgtatg cagataaagg tcaaatttat
    10381 ggatgtatta ttcaaagaaa ttatcgtcat ccgatatctg ggcagataga agatagcgga
    10441 ggggagcatt cctttgatat tggtcaaggt atggttgaag gaactgtcta tagtgatgcc
    10501 atgctagaag tatctgatgc tggaaagatc gttcttactt ttcgtatgag cttagctgat
    10561 tattcgggca attatcagtt ctggatacaa cctggaggaa ctggaagctt tcaggcagtt
    10621 gattacaata tcacccaaaa aggtactgat accaatggga caacactaga tattgctatt
    10681 agtttgccta ctgtaaatag tatcattcga ggcagcatgt ttgttgaacc tatgggcaga
    10741 gaagtggtct tttacctgtc agcttcagag ttaatacaaa agtattcagg taatatgttg
    10801 gcccagcttg ttactgaaac agacaattct caaaatcaag aagtaaaaga cagtcaaaag
    10861 cctgttgata caaaactagg agaaagtcaa gatgagtctc acacaggtgc tatgataact
    10921 cagaataagc ctaaagccaa ctcatcaaat aacaagagtc tatcagataa aaaaattctt
    10981 ccttctaaga tgggcttaac gacttcttta gagttaaaaa aagaagataa gtttcggtct
    11041 aaaaaagact tatcaatcat gatttactac tttccaactt tttttctgat gttaggaggg
    11101 tttgctgtat gggtttggaa aaagaggaaa aaaaatgata aaacgatgta aaggaattgg
    11161 tctagcctta atggccttct ttttggtagc ttgtgtgaat cagcacccta aaacggctaa
    11221 agagactgaa cagcagagaa ttgtagccac ttcggttgct gtggttgata tctgtgaccg
    11281 tttaaattta gacctcgttg gggtttgtga tagtaaatta tatacccttc ctaaacgcta
    11341 tgatgctgtt aagcgtgtgg gtttacccat gaatcctgat atagagttga ttgcttcttt
    11401 gaaaccaact tggattttga gtcccaattc tttacaagaa gatttggaac ccaagtatca
    11461 aaaattggat actgagtatg gttttttgaa cttacgaagt gttgagggca tgtaccagtc
    11521 cattgatgat ttagggaacc ttttccaacg tcaacaagaa gcaaaagaat tgcgccagca
    11581 ataccaggac tattatcgtg ctttccaagc taaacgtaag gggaagaaaa agcctaaagt
    11641 gcttattctt atgggcttgc caggtagtta tttggtggcg acgaaccaat cttatgtagg
    11701 gaatcttttg gacttggcag gtggtgagaa tgtttatcag tcagatgaga aagaatttct
    11761 atcagctaat cctgaagaca tgctggctaa ggagcctgac ttgattttac gaacagctca
    11821 tgccattcca gacaaggtaa aagtgatgtt tgacaaagaa tttgctgaaa atgatatttg
    11881 gaaacatttt acggcagtca aggaagggaa agtctatgat ttggacaata ccctgtttgg
    11941 catgagtgct aaattgaact acccagaagc cttggacacc ttaacacagc tttttgacca
    12001 cgtgggagat catccgtaac atgacagcat cagatttaca aagggatcaa tccctactgg
    12061 ctaaaaaacg tttcagaagt ggtctttatc tagttctttt aattctcagc ctcctatttt
    12121 tggcggttat tgccttatcc cttggtggtt tggcggtttc ttatggggca attgtcaagg
    12181 gactgtttgt ggcttatgac ccccaagtgg ctttgattta tgatttgcgt tttccaagaa
    12241 ttgtcattgc tttattagca ggagcaggga tagctgtttc gggagttctt tttcaagcag
    12301 tgttgaaaaa tcctatttca gaccctgcta ttatagggat ttgtagtggt gctagtttta
    12361 tggttttagt ctctagttta cttctgccgc agttgctgct gtatggtcca atcgtatcct
    12421 ttttaggagg cggagtgtct ttcctgctga tttatggttt agcatggaag aaagggctta
    12481 atcctattcg gcttattcta acagggattg ctattaatgc tttatttatg gggttatcaa
    12541 ctgctttaac cagctttttc acctcagcta gtcccatggt caatgctctt ttagcaggtc
    12601 atattagtca aaaaacatgg gctgatgtag gggttttatt cccttataca ttcattggct
    12661 tgttactagc tttgttattg tcaaaaactt gtaaccttct tcttttagat gatcaggtga
    12721 ttcgtcattt aggaatcgat gctacagcgt tacggttggg aatttccttg gttgctgttt
    12781 tattggcttc ggtagccact tcgatcgttg gagtggtttc tttcctaggc ttgattgtcc
    12841 ctcatatgag ccgcttgctg gttggaagta agcaccaaat cttaattcct ttttcagctt
    12901 tgcttggagc ctttgtcttt ttgctagccg atactttagg aagaagtctt gcttacccat
    12961 tggaaattag ccctgcgatt ataatgagta ttgtaggcgg gccttacttt atttacctgc
    13021 taaggaggtc tgatattata tgagtaagaa cagcagtcat attcaggtgc aaaacctttc
    13081 ctttgcttat gaggaaaaac ttgttttaga tgacctgacc tttagcattc caaaagggaa
    13141 aattaccact attatggggg caaatggcag tggcaagtca accttattac aattattaac
    13201 caaaaacctt ccgttaaaac aagggcaggt ttggcttgag caggaagaat tagcaacgat
    13261 ttctctcaag gcttttgcga aaaaagtggc agtggtacac caataccatc aagtggtcga
    13321 aggtttgtta gtgggtgaat tggtagccat ggctaggctt gcccgtcgtt ctttttttaa
    13381 aactactacc aaagaagatg aggagcgcct tgcttgggcc ttagaagtaa cggctttgag
    13441 tgattatgtt tatcgtgata tccaacacct ttctggtggt gaacagcaga gggtttggat
    13501 tgccatggcc cttgcccagg atacagatat tattttttta gatgagccaa cgacttattt
    13561 ggatattaag taccagcttg acattctcaa gctgattact aaaatcaacc aagagctagg
    13621 cctaacgatt gtgttagtat tacatgacat caatcaggcc ttgtctcttt cagaccatct
    13681 tattggactg aaagatgggc gactttatgc ccaaggtcaa ccaagagacc tccttgatca
    13741 acagtttatc agagatgtct ttggtgttga attgcccttt gttgagagaa atggtcaaca
    13801 gtttgtcctc acttcattgg tcaatgaaac caatggtatt agaactcaaa ggagagatag
    13861 gaacaagaac agatgatgga aacagaagat acaatatcaa ggggaaaaag gaaaagactg
    13921 ttaaaacgat tacgtgaacg aattgcacca aaaaggtatt tgctttatgt gtcagccttt
    13981 ttatcttggt tacaatttgt gatgaggatg atcagttttt acctcattgc caaaacgttt
    14041 tcgaccttta ttttgggtca tgctattgcc ttaggacgct tggcaggttt actcctactt
    14101 ttaaatgtgg taggctttgt tcttgctata ttaggcaagc aactgcaagg gatcgcttca
    14161 caatttgcta gagattcact caaacaatct ttctttgagg cttttattga tttagacggg
    14221 caatttgatg ctcatgccag tgatgctgat attttaacgt tggcttcaca ggggattgat
    14281 agtttggata cttattatgg ttactatttg tctttgtcta tgagaaccaa gtggaactgc
    14341 acaactatta tgatactagt ctttttaatt tatccattgg caggccttgt ctttttagga
    14401 gttctgcctc tgattccact ttcaatcgtt gctatgcaaa agcggtctaa gcaaattatg
    14461 agtcattatt ggtcttctta tatggatgtt ggtaatttat ttatggatga cttaaaaggt
    14521 cttaatacac tgtattctta tcaagcaaca gaacgttacg agcaagaatt ttcgggtaag
    14581 gcagaacagt ttcgaaaggc taccatgtct ttgcttggct ttcagttaca agcagttggt
    14641 tatatggatg cagttatgta tctgggaatt ggtttgtcag gttttttagc cgttcaagct
    14701 ttggcaacag gccagttatc tttttttaat ttcctatttt ttctcttgat tgctacagaa
    14761 ttttttacac cgattcgtga gcagggttat ggcatgcact tggtcatgat gaataccaaa
    14821 atggctgacc gtatctttag tttcttggat agtgttccag caagaaaaga taacaagagt
    14881 aaaacagcaa taaactttaa ccagattgac atccaaaata tttctttagc ttatgagaaa
    14941 aaaacagtgc ttagtggggt taccatgaca ttaacgaagg gccaactaac agctatcgcg
    15001 ggggtgtcag gacaaggaaa aacaagtcta gctcaactcc tcttgaaacg ccagtctgca
    15061 acgactgggc atattttatt tgacggttta gacagtgaca atttgtcgca agaaactatc
    15121 aaccagcagg ttctttatgt atcggaccaa tctaccttat tgaaccgtag catttacgat
    15181 aatttaaggt tagcagcaaa tctctctaaa aaagaaatct tagattggat agatcaacat
    15241 ggtttgttaa gcttcatcaa ctggctacca gatggtcttg acacaatagt tggtgaaaat
    15301 ggtaacctgt tatcaccagg ccaaaagcaa caggtgattt gcgcaagagc tctattaagt
    15361 aagaggtctc tttatatctt tgatgaggca acatctagtc tagatgcaga aaatgaacgt
    15421 attattgaca atttaataac gagattagct aagacagcaa tagttattgt gattactcat
    15481 aagatgtctc gactgaaagg agctaaccaa gtactctttt taaacacagg gcagcctgct
    15541 tgtttaggca aaccttgcga cctttatcgg gaccaaccaa cttatcgtca cctagttgat
    15601 actcaagcaa gactggaggc aagtatttat ggctaaacct aacagatcta ccttaagcct
    15661 ggtttggcgt ttattaaccc taatgaaaac tctgctacct tggattatct tggctgttgg
    15721 ctttgctgtt atgggttttg tcatcacggt aagtattcca actggaatag cttatttagg
    15781 actactagct attagacaag aagtgattcc aatattagct ttatatcttt tgattgctct
    15841 agccttttta agaggttttg ttcgttatgg agagcattat tttggtcatt ttgttgcttt
    15901 tcatagttta gcagctttta ggaacttgat ctttaagaaa ctaagagctc tttctccagc
    15961 ttgcttggat agtcaagaca gtggttattt gcttaaaatg attggagaag atattgaggc
    16021 attagaagtt ttttttgccc acacaatcgc acctatttgt acagcaatat tgtctgcagg
    16081 tttaatgttc tggtactttt gtcaaagtag ttggcagtta gccttattag ctttggcaac
    16141 ctatgcttgt ttagccattg ttatacccat ttattttgct aatattttac aggttttact
    16201 aaaaagccaa aatgaaggtc gaaaagatta cctgtcttat tttttagaga gtttacgatc
    16261 agtcaaagat cttttgcaat ttcaggtatt agacgagcaa tttgaacgat taataaaaaa
    16321 aagtaatcat gtaaatgctc ttgatcgtaa cgtagcgcaa gcccaatttt tgcaaatggc
    16381 attgactttt ttctggcttg gcttaatgat cttagcattt tcttatatgg tttttgatgg
    16441 gatatgccat gacagcttat catttgataa aggcttatta acttttattg ctttcactgc
    16501 ttcgttttct ccttttttag aactaggacg tttgccatta ggttttaagc gtgctatgaa
    16561 tgcggctcga aatatttttg accttctaga cgaaaatgtc atagtagatg aaggcacaaa
    16621 acaaatagat cgtttaagga gtgtttcttt tgaggacctc agttttgctt atccaaagcg
    16681 ccaagagctg gtttttaagg atttaacagt tacctttcaa gaaaagggga ttattggcat
    16741 taaaggcgaa tcaggatctg gtaaatcaac tttggtgaaa ttaattatga aatggtataa
    16801 ttggaagaca ggagatattt ttcttaatga taggaatagt tgcttactaa atgctgctaa
    16861 attacaagat actattgctt atgtgccaca aacagcgcag cttttccaac agtctatccg
    16921 tgaaaatctt atctttggcc gtcaagatat ttcagatgag tccatttgga atttagctga
    16981 ggcttgtggt atgaaagaca gactgttagc ttgtaaggaa ggtttggata cgattatcaa
    17041 gagtccttct gacttttcag ctggagaagg tcaacgttta gagttgatgc gagctttatt
    17101 gaaagatgcg agttgctata tttttgatga acccacgtca aatttagatt ctctaaatga
    17161 agctatcttg cttgatttaa ttaaaacaca ttgtcaagga ttggtcttct taatttctca
    17221 caggccatca accctagctt gtgttgatca tctattttgc gtaaaaaatg gttccctaaa
    17281 agaggtgaat aaaaaatgaa acagttaaca ataaaagata ttatgataac aggcgcattt
    17341 gccgcgctct actttatttg tgttggtcta ggcacgttta ttaacatctt ttttgatcgc
    17401 tcaggaaata tgttatatgc ccctgccttt gcagctttac tggggggaac aatttatttt
    17461 cttttgattg ctaaattgca aacatttggg ccaataacat tattaggatt gatgatggga
    17521 ggttttttct tccttagtgg tcactttttt gccgcgatgt ttcccagcat tattttcggt
    17581 ttaatagcgg atattattgc gtctttagga aaatacaagt caaggttttt taatgaccta
    17641 tcttatatgg tttttgcttt tgtcaatagt ggccctattt tgctgatgtg gttgttgaaa
    17701 gatgcctatg ttgaaagttt gttagcccgc ggtaaaagta tgacctatgt caatcgcatt
    17761 atgtatgatt ttagtttagg gcatgttatt tggtttgtag gaattgttct tgcaggagcc
    17821 ttattagggt cagtttttgc acattattta ctaaagaaac attttatcaa atcaggattg
    17881 ttatcatgag gcttgatgtt cgcaccaaac tgcttttgtt ggtacttgcc aatgcctgct
    17941 tcttttttcg tgttgatggc tttttagaat ttataattgt tatttttctc ttattacttt
    18001 tgtctgcttt aaataagaaa aagctagcgt tcaagttggc ggttgtttat ctgttaatga
    18061 tcggtctatc tgtaatcccg ctatcgattt tcccttctta tcttgaccac ttattgagtt
    18121 ttgtctcaat agcaggaagg ttagttttcc cttctttact agcaggttta attactatta
    18181 agacaactac catctacgaa ttggttcatg gattacgcaa atggcgtttc ccagaagtct
    18241 ggctattgac cttggccgtt atgtgccgtt tcataccaat gattagacaa gaatgttgtg
    18301 ttattcatcg ctctttaaaa atcaggggga ttattttaac aaaatggtct attttgatca
    18361 gacctaaaca atacttggag tatttaatgg ttccattgct tttatctttg ataagaagta
    18421 gccaagaact aactatcgct agtctaacta aagggctagc agtcaacaaa ggcaccagtg
    18481 aatgctttag ctcacactta acatggaaag attggggggt gcagatttgg attactgtta
    18541 tcataatcat cacgatactg caatgatttc agcagaacaa cttgttttta cctatcatga
    18601 tcaaaaaaat ccagcttgtc agatatcgac ttgtcaaatt gcctctggac aattcattgt
    18661 tttgtgtgga ccttctggtt caggtaaatc taccttttta aaacttctta atggcataat
    18721 tcctgattat tatgctggaa aatatgaagg tagactagat gtggctgatt gccaagcagg
    18781 cagagacagt gttgaaacat tttctagatc tgtggcctct gtttttcaaa atccagccag
    18841 tcagtttttc tatcgcgaag tccaacacga actagtcttt ccttgtgaaa atcaaggttt
    18901 agatgcaaag gttatcatga agcgtctttg gactttagca gaagattttg cttttgcaga
    18961 gctccttaac aaggatatgt ttggattgtc aggagggcaa aaacaaagag ttgctattgc
    19021 aacggccatt atgcaaggta ctaatattat gctttttgat gagccaactg ctaacttaga
    19081 tagtgcaggc atagctgctg ttaaagccta tcttacccaa ttaaaagcag caggaaaaac
    19141 cattattgta gccgagcatc gcttacatta cttgatggat ttggcagata actttttcta
    19201 ctttaaaaat ggtagattaa cagataagtt aacaacacaa aatttgctag ccttgacaga
    19261 tgaacaacgg caagatatgg gactacgtcg cttagacttg tctgacctaa aacctgtgtt
    19321 agctggtaag attgagagtc aacattatcg cccagatgat agcctgtgta ttgagcatct
    19381 aacagttaga gcgggaagca aaatacttag atgtattgaa cagcttagtt ttgctgtagg
    19441 aagtatttct ggcattacag gatcaaacgg gcttggaaaa tcgcaattag tttattatat
    19501 agctggtatc ttagacgata aaaaagcaac tattaagttt caaggcatac ctttatctgc
    19561 caagcaacgt ttatcaaaga ctagtattgt cttgcaagaa gtttctttgc aactatttgc
    19621 agaatcggtt tcaaaggaag tcaacttggg ccatgaacga catccacgga cgacagaagt
    19681 aatagagcgg ttatctttaa cgactctttt agaacgtcat ccagctagtt tgtcaggagg
    19741 tgagcaacaa agagtgatga ttgccgctag tcttttggct gataaagata tcttaatttt
    19801 tgatgagcca agtagcggac ttgatttgtt acaaatgaag gctttagcta atcttctcat
    19861 gcagctgaag acccaacata aggttgtcat cctcatttca catgatgaag aacttctaag
    19921 tagtgtctgc gataccattt atcaaatgct accttaacga gcccctagaa ctgtttaaaa
    19981 gtactaaaag gcttttatct gaaaataaat aggaactctt gtataataga tacaagagtc
    20041 agaacgtaga caaccccagt tttatgctca aaaagcatga atagctctgc tgatttgaca
    20101 ttcggtttcc gatttttaca cacaaagtga gccaaaacag atgctttttg ctgtggtaaa
    20161 agagtggcgt caatctcgta ttgacgccac tcgggatttt tgagacctca ggctcaaaaa
    20221 taaaggcatg gaattccaaa gaacgtcgct gccgtaagca ccacctaagg aaagtatcac
    20281 gacaaacttt gtcttcaatc tgacaagagt ttttgtgaag ggaaaaagat aatgatatta
    20341 acagctccta tgtccaactt aaagggattt ggaccaaaat cagcagaaaa atttcagaaa
    20401 ttagatattt atacagtaga agatttactg ctttattatc cgtttcgcta tgaagatttt
    20461 aaatcaaaat ctgtttttga tttagtggat ggtgaaaaag cagtcattac aggcttagtc
    20521 gttactccag ctaatgtaca atattatggt tttaaacgta accgtttaag tttcaaattg
    20581 cgtcaagggg aagctgtctt aaatgttagt ttttttaatc aaccctattt agctgataaa
    20641 atagaacttg gtcaagaggt agctgttttt ggtaaatggg atgccactaa atcggctatt
    20701 actgggatga aggttttagc tcaagttgaa gatgacatgc aacctgttta tcgcgtagct
    20761 cagggaattt cacagtctac tttgattaaa gctattaagt cagcttttga aatcgatgcg
    20821 catttggaat tgaaggaaaa tttaccagct actttattgg aaaaataccg attgatgggt
    20881 cgtagtcagg cttgtttagc tatgcatttc ccaaaagata tcacagagta taagcaagcg
    20941 ctccgtcgga ttaaatttga agaattattt tactttcaaa tgaaccttca agttttgaaa
    21001 gccgaaaata aatctgaaac aaatggtttg cctattcttt atagtaaacg tgctatggag
    21061 acaaagattt cctctttacc ttttattcta acgaatgctc aaaagcgctc tttagatgac
    21121 atattatctg atatgtcatc gggagctcat atgaatcgtt tattgcaagg agatgtagga
    21181 tcaggaaaga cagtcattgc tggtctatca atgtatgcag cttatacagc aggttttcaa
    21241 tcggctttga tggttccaac ggaaatccta gctgaacaac actacattag tctgcaagag
    21301 ttatttccag atttatcaat cgctatatta acttcgggta tgaaagcagc tgtcaagcgt
    21361 acggttttag cagctattgc aaatggctcg gttgatatga ttgtaggaac tcatgctctt
    21421 atccaagact cggtacagta ccataaactg gggcttgtca ttacagacga gcaacatcgt
    21481 tttggtgtta aacagcgtag aattttccgt gaaaagggag aaaatcctga tgttttaatg
    21541 atgacagcca ccccaattcc ccgaactcta gcaatcacag cttttggaga aatggatgtt
    21601 tctattattg atgaattacc tgccggtcgt aaacctatta tgacacgctg ggtgaaacac
    21661 gagcagctag gtactgtgtt ggaatgggta aaaggtgaat tgcaaaaaga tgctcaagtg
    21721 tatgtcattt caccgttgat tgaagaatca gaagctttag atttaaagaa tgcagtagca
    21781 ttgcatgctg aattatctac ttattttgaa ggaattgcta aggttgctct tgtacatgga
    21841 cgtatgaaaa atgatgaaaa agatgctata atgcaagatt tcaaggataa aaaaagtcat
    21901 attttagtat ccacaacagt tattgaagta ggggtaaatg tcccaaatgc aacgatcatg
    21961 attattatgg atgccgatcg ttttggatta agtcagttac atcaacttcg tgggcgtgtt
    22021 ggtcgtggat ataaacaatc atacgctgtt ttagtggcta atcccaaaac tgattcgggg
    22081 aaaaaacgaa tgacaatcat gacagaaacg acagatggtt tcgttttagc tgagtcggat
    22141 ttaaaaatgc gtggttctgg tgaaatcttt ggtactcgtc agtctggaat ttcagaattt
    22201 caagtagctg atatcgttga ggattatcct attttagaag aagcacgcaa agtttctgca
    22261 gcgattgttt ctgatcctaa ctggatatat gaaaaacagt ggcaattagt ggcacaaaat
    22321 attagaaaaa aagaagttta tgattaactt aaaacaagtc gttgttttac aaatatttag
    22381 ttagttttga gataaactgt tataaagtat aaagaggtca ctatttctgg ccttttttac
    22441 ttatgcttta cgatgagact gctatgtgaa gcagtattaa cccattttca gtataacttt
    22501 tttattgcta aaataatcat attattaaaa ttcttattta tattttttta ataaaaagaa
    22561 gaacttgtca caaccgttta cagatgttat tatgtgtaag atattgtatt gatcgataag
    22621 tacaaaaaag gagcggaaaa tgacacagca atcaatgtta ctaagtattg agcaagtaaa
    22681 taaatcctat ggtaaaaatc aggttttaag tgatatctct tttgatattt acaaaggaga
    22741 aatttgcggc cttgtgggtc aaaatggtgc tggaaagaca acgttaatgc gtattttatc
    22801 tggcctaatt ggaaaagatt cagggcaaat caaacagtta caaccctatc gaatgggatc
    22861 aattattgag tcaccgacac tttatcccaa tatgacagct catgataatc tttactatgc
    22921 agcgttgcaa ttgagattag ctgatgcaaa agagcgcata catgaggttt tggaacttat
    22981 tgggttagaa aaagtgagca aaaagaaaaa ggtgaaagat tgttctttag ggatgcgcca
    23041 acgtttggct attggtcttt cgatactgga ttttccagaa tttttaatct tggatgaacc
    23101 cattaatggt cttgatccag caggaatcaa agaaatgcgt cagattattt tgaacctaag
    23161 agattgctat ggtattacga ttttgatttc cagtcatatt ttatcagaat tagacttagt
    23221 tgttgatcgt tacgtgatta tgcataaagg caaagttatt aagagtatgg acaaagcaga
    23281 gcttaaagct caagtaaaag tacaaattgc ccttcataca agcgatgatc agctggtaaa
    23341 aaatagactt ttagaattgg ggcttagagt tgagactgat ggtcagatgc tactaataaa
    23401 accaacttta tcagtaatgg agcttatcaa aattgttcta gatctgcctg ttgagatttt
    23461 tgacatttat catcatcaag tgagctttga acattattac ctcgatttgt taggtaaaga
    23521 tgcagcatca ccattaattt agaaagaggt ttttatgatt tcctatctta aagcagattt
    23581 atttcggata cgccaagagc gtttagctct attttcttgt atgctacttg ttgtcattgc
    23641 tgttggtgta gcctatagtt ttcgcaagac acctaaccaa gtcatcatga tacaaatcat
    23701 taatattatt actgattttg tgacgctttt ctttttaaca ccagcccgta tcttttttag
    23761 tgatgactat aactaccgta cgattaataa tgttgtggtc aaacaacaaa atcgtacttt
    23821 aattataatc tataaactgc tagttagttt tggcttatct cttttattta ttagtttaac
    23881 ttatcttctt agtgctttag catttcattt atttactggt caagcatact atggaatagt
    23941 catagatcgg atgattaaac aactgccttt ttatattgct attattgctt tgtgtcaatt
    24001 tttgtttaat atacttcgta aaacttatca gtcaatcaca gcttatatac tttatgtcct
    24061 tctttttgat aaagtatctg ctactttagc aaaccatttt tttaagttag atattagccc
    24121 agttttgatg tttaaacacc tatccttgtc tcttggtgat aaacaccttt ctagtactag
    24181 catattagtg gcctttggtt taactctttg ttatctttta ggcaatgtct ttcttttttc
    24241 caaacgagaa ctaaaataaa gggtaatatg tgctttgttt attttaaaag acaaagaagt
    24301 tcttagaaaa aggtcgtctt catcattact aaaaaaggat aagcaagtag ttttgttatt
    24361 attcaagtaa gctcatactt aatgagacaa aataaagact tgtttacccg gtatctgatt
    24421 gctaagagtt ggatttattg gaatactggt ctcaaactgt tatagaaatg attatgagtg
    24481 cacaatctca tagtttgaaa catagttgtt tattctagac atttaggaga tgtcctaatt
    24541 taaagcttaa agtactagaa atgtcccact aatatgtttt agtgggacat ttctaaagga
    24601 agctagatta tccttcaata taatctttta gctcttgacc agtaagtccg gcgttgagag
    24661 caattaataa ctttagacgg gcttttggag cattcaattc ttttacaaac ataacacctg
    24721 cttcttgtag catcgcacca ccaccttcat aagcatagac aggttctgcc ataccattga
    24781 aacaacggga aacaagaatg acaggaatac ctaaagtaat taagtgctcg atctccccaa
    24841 ctgctaatgg tgggacattt cctgccccta gagcttcgat aactagacct tgaatgctac
    24901 ctggagttaa tagactcaag atactaccat cgcccatacc tgcgtatgct ttgataatgg
    24961 ggatggttcc agaaatgcat ctcaagtcaa aacgaatacg aggttcagca gttttgaaaa
    25021 aaagtaggtc atttttcatg atgataccaa gcggtccgtg tgtgggtgtt tggaaagttg
    25081 aaatattggt tgtatgtgtt ttagtaacat atttagcagc atggatttca tcgttcataa
    25141 caacaagtac ccctttttct ttagctttat cactacttgc aactctaagt gcggtaaggt
    25201 aattatatat gccatcacta ccaacttcat tagaagacct catagcacct gttaggacaa
    25261 caggtatatt agtaggcaat gccatggtat ctaaaaaata agctgtttct tctaaggtat
    25321 ctgttccatg tgtgatgact ataccatcaa agacatcagt tctttcttga atatgatgat
    25381 aaatagataa catgtggtga ggcgtgatgt gaggactcgg aagatttaga aaatcactaa
    25441 cggtaagctg aatatcttgg gctgcagcat gtattttcgt cataggatta tcttgatttg
    25501 gaacaaccct accagagtta tcagcttgca tagaaatggt tccaccagtg tgtaagacta
    25561 ggattttttt catttgattg tcaaacttcc ttttatttat gatataatct attctatcat
    25621 aaacacagga ggcaaaagaa ggttttgaca gtaaaagcag tcttttttga tattgatggg
    25681 acccttctca atgatcgtaa aaatatccaa aaaacaacgc aaaaagccat ccaacaactc
    25741 aaaaaacaag gcattatggt cggtttagca actggtcgtg gaccgggatt tgtacaacct
    25801 tttctagaaa attttggatt agattttgcc gttacttaca atgggcaata tatcttaaca
    25861 agagataagg tcttatatca gaatcaattg ccaaagtcga tgatttacaa agtgattcgc
    25921 tatgccaacg aaaaaaagcg agaaatttct cttggaacag cttctggatt agcaggatcg
    25981 cgtattattg atatggggac tagcccattt ggacaagtca ttagtagttt tgtgcccaaa
    26041 agttgggcaa gaacagttga gggtagtttt aagcatttga ttcgccgaat caagcctcag
    26101 agttttagaa atttagtaac tattatgcgg gagcctattt atcaggttgt tctggtagcg
    26161 tcacaagctg aaactaagaa aatacaagag aagttccctc atataaaaat tacaagaagt
    26221 agtccttatt ccttggatct gatctctgtt gatcaatcaa aaataaaagg aattgaacgt
    26281 ttgggagaga tgtttggatt tgacttgtct gaagtgatgg cttttggaga ttcagataat
    26341 gaccttgaaa tgttatcagg agttggtatc ggtattgcta tgggaaatgc tgaaactgtg
    26401 gtaaaagatg gagcccattt cactaccgac tctaataata atgatgggat ttccaaagcc
    26461 ttagctcact acggtctcat ccattttgat atagagaaga gctttaaaag ccgtgatgaa
    26521 aattttaata aagtcaaaga ttttcatcgt ctgatggact cagatactat tgaaacaccg
    26581 cgtagttata ccatttcaga agctggttat aggtcaggct ttaaagtaga agaaattgtt
    26641 gagtttcttt acgcagcaag caagggagac caacaacaat ttacacaggc tattttcgat
    26701 ttgcatggtg ctgttgacca agcagctaat aaggtacaag ctaaaaaaca tgttgaaacg
    26761 cccctgattg ggcaagttga tgccttagcg gatttgcttt attttactta tggttctttt
    26821 gtactgatgg gagtagatcc acaacctata tttgaagcag tacatgaagc aaatatggct
    26881 aaaatttttc cagatggcaa ggcacacttt gaccccgtta cccataaaat tcaaaaacct
    26941 gactattggc aagagcgtca cgcacctgaa gtagccataa aaaaagagtt agacaaacaa
    27001 ttacaaaaat cactacaacg attcgataaa tagaggttta ctcttttaaa tatcaagaaa
    27061 taaaaagata ttgactagac ttagctcagc acaaaaaaac aagcaatttc gttgtagatg
    27121 ctgcttgttt tttggtgttt gaaaattgta atagactaga gtgttttagt gctatctcgg
    27181 actacaagta agtcaatctt agcgtgtcgc ataatgtact cagaagatga gccaataagg
    27241 aggcgttcaa aggtattaag accagtagct cctaccataa ttaaatcagc gttctcacga
    27301 tctggaatat cgtgagctag taagtttttg gggttgccaa attcaataat ttgtttgatg
    27361 tttgtaattc ctgctatctg tgcttgtttt tcaaaattat ctaaaacatc cttagcttct
    27421 tgttctaatt tttcatagat gtaagtatca aaagtagcta cgctttgcaa ggcacgggta
    27481 tcaataacgt gtactagtag taaggtagcg tcgttacgta gtgctacgtt aacgccttta
    27541 ttgaaagcta attcagactc ataagagcca tcaatagcaa cgaggatacg tttatatttt
    27601 agtgacatag aactgtcctc ctttaacagt ttgacaagaa tagcttttat tctttttttc
    27661 attatactct tttttgagtc attttgaaag cgatccatta tttttgctaa actaaagact
    27721 gtattatcgt ctcataagac ctgtgttaaa acgattagct gtcctaagct ttgatggata
    27781 aattctttct attttaagta ttttggttta taatatggaa tacgaggtgt atgagactat
    27841 gaaaattatt gaaaaatcat caaaattaga acatgttgcc tatgatattc gagggcctgt
    27901 tttggatgaa gctaatcgca tgattgcgag tggtgaaaaa attctgcgtt taaatactgg
    27961 caatcctgct gcttttggtt ttgaagcacc agatgaagtg attcgtgatt taattgtcaa
    28021 cgcgaggcta agtgagggct attctgacag taaagggatt ttttcagcgc gtaaggctat
    28081 catgcagtat tgccaactca agggcttccc agatgttgac attgaagata tttatttggg
    28141 aaatggcgtg tcagagttga tatccatatc ccttcaagct ttgctagata atggcgatga
    28201 agttttagta ccaatgccgg attatccttt atggacggct tgtgtgagtc ttggtggagg
    28261 aaaagcggtc cattatcttt gtgatgaaga agctggttgg tatcctgata ttgctgatat
    28321 caaatcaaaa atcacgagtc gcaccaaagc tattgtggtc atcaatccta ataacccaac
    28381 aggagccctt tatcctaagg agattttaga agacatcgtt gctttggcaa gagaacacca
    28441 gctgattatt tttgccgatg aaatctatga tcgtttggtg atggatggta aagagcatat
    28501 tgctattgca agtttggcac ctgatgtttt ttgtgtatct atgaatggtc tttccaaatc
    28561 tcatcgtatt gctggttttc gtgttggatg gatggtctta tcaggtccta aagaccatgt
    28621 taaaggttac attgaagggt taaacatgct tgccaatatg cggttatgct ccaatgtttt
    28681 agcccaacaa gttgttcaaa cttccttagg aggtcatcaa tcagttgatg cactgttact
    28741 gccaggaggg cgtatttttg agcaacgtaa ttttatttat gaagctatta atgctatccc
    28801 tggcttatcg gcagttaaac ctgaagcagg tctttattta tttccgaaaa ttgatcgtca
    28861 gatgtatcgt attgatgatg atgaagaatt tgtcttacag ttattaaagc aagaaaaagt
    28921 gatgttggta catggacgtg gttttaactg gaaagatcca gatcacttcc gtattgttta
    28981 cctaccaagt gtagaagaat tagaagatgt ccaagaaaag attacacgtg tcttatacca
    29041 gtatagacgt taatgcaatg ctcatctttg attaataaaa atagcgtttc ttaaaagaat
    29101 gtgaccctat gctctaacaa gctagtgctt atctccttta aatgaagtga taataaggca
    29161 tcaatagttg gaattgtagt aagaatagaa aattttctga taattccttg caaaagcgag
    29221 ttagctttgt tataatgaaa gcgcaaataa ttcaaaggaa aaggaaaaaa atgcctaact
    29281 tattagaaaa aactcgtaaa atcacatcta ttttgcagcg ttccgtagat agcctagaaa
    29341 cagaattacc gtataacaca atggcatctc gcctagcaga tatcattgac tgcaatgctt
    29401 gtattatcaa tggcggcggc acactgcttg gttatgccat gaaatataaa actaacactg
    29461 atcgtgttga ggaatttttt gaagctaaac aatttccaga tacttatgta aaggctgcta
    29521 gccgagttta cgatacagaa gctaaccttt ctgtcgaaaa tgaattgact atattccctg
    29581 ttgagtctaa agacacttat ccaggaggtc taacgactat tgcgccgatt tatggtggag
    29641 ggatgcgcct tggatcactc attatctggc gtaatgacaa tgagtttagt gatgatgatt
    29701 tgattttggt tgagatctca agtactgttg tggggattca actattaaat cttcagacag
    29761 aaaacttaga agacaccatc cgtaaacaaa cagcggtcaa catggcaatt aatacgcttt
    29821 cttattcaga aatgaaagct gttgcagcaa ttcttggaga gttagatggt aacgaaggac
    29881 gattgacagc ttctgttatt gctgatcgta ttggtattac ccgttctgtt attgtcaatg
    29941 ctctgcgtaa actagaaagt gcagggatta ttgaaagtcg ttctcttggt atgaaaggga
    30001 catacctcaa agttatcaac gaaggtattt ttgctaaatt aaaagaattt taaatagaaa
    30061 aagacaacat ctcttgaaaa gagatgtttt ttgctgttaa tggtagatgc aaatagatgt
    30121 cttgatacct gtaataaaaa ctgatacaat gccatatata agagataagg ggagaggttt
    30181 ccctgtttag gagatagtga tgagagcatt gatttcaatt gattacacaa atgattttgt
    30241 agcagatgat ggtaaattaa gtgcaggtaa atctgctcag gctattgcca ctaaaatagc
    30301 agaggtaact aaaacggcat ttgatcaagg agactatatt ttttttgcta ttgattgtca
    30361 tgatcaaaat gattcttggc atcctgagag taagctattt gcagcacata atatcaaagg
    30421 aactactgga cgccatcttt atggtccact agctgaagtt tacagttata tgaagcaaca
    30481 tcccagagtt ttttggattg ataagcgtta ttattcagct ttttcgggga ctgatttaga
    30541 tattagacta cgagaaagag gtatcactca attagtgtta acaggagttt tatctgatat
    30601 ctgtgtctta catactgcta ttgacgctta tcatcttggt tatcaattag agattgttaa
    30661 atcggctgtc gctagcctta caaaagaatc ttatgagtgg tctttggctc actttgagca
    30721 ggttcttggt gctaagctta ttaacgatta ctaaaagagc ctaccaaact attgattcag
    30781 tgactaagag tttggtaacc gtaatcattg ctctatgtgg ttttaccgta tgtatgggtt
    30841 aggtagatga ggtatgtgac atgctggtca gaattagtcc tgatgattct tgtgctgtct
    30901 aaaaggcaac taaactttgg actgtgtcag atagaacaca tgtttttttg aaggagacag
    30961 gattttagct gtttgagaaa tgatttgagt tgatggttta gaggatcgtc tcacagccat
    31021 tagacaaact ctagtctttt cagcattaga atataaataa agcttcaaac tcttgaatgc
    31081 tagagtctgt accattttta tcttaggctt atcacatcac atgttgttac aatcgttgag
    31141 gatttggtaa attagaataa agcacccctt tactaccttc gtaaacatat taccgacttg
    31201 aaagaacgtt actttttctg tgatgtttgt aggaaaatac ttggaagaat acgttgacag
    31261 gggtattttt gataaggagc cgttccagac ctttgatcag aaagggattg gccgtctctt
    31321 tagcccgttc ggttaagcct gagttgaaac ttggtatttg tggggaacat ggtggcgatc
    31381 ctgcttccat tgccttttgc cacagccaag gcctgaccta cgtttcttgt tcgccattta
    31441 gagtgccgct tactcgcttg gcggctgctc aggctgccat caaagcttca ggccacagtc
    31501 ttacccaaga caaatagagt ttagtttgtc acacttcctg actaaggttt tctgacctta
    31561 gtcaggaagt tttttgctgt atggctttct agaattgcat tagtcaccta tggtaaatgg
    31621 gagcaattgt gatataataa ttgagactat gtaaaaatga tgtgaggagt ttttccgcta
    31681 cctttggaga atagcagggc tgttctttgg aattggaata cttctgatca tcttggatgg
    31741 gagaaatcat gaaaatttct gaagaagaag ttcgccatgt cgcgaagcta tcaaaattat
    31801 cattttcaga aagtgagaca acaacctttg caacgacctt atccaaaatc gttgatatgg
    31861 ttgaattgct gaacgaagtt gataccgaag gtgtcgccat tacaacaacc atggcagata
    31921 agaaaaatgt gatgcgtcaa gatgtcgctg aagaaggaac agaccgtgcc ttgctcttta
    31981 aaaatgttcc tgaaaaagaa aatcacttta tcaaggtacc tgctattttg gatgacggag
    32041 gagatgccta atgtctttta atcataaaac cattgaagag ttgcatgacc tccttgtagc
    32101 taaggagatt tcagcaacag aattgaccca agcaacactt gaagacatca agtctcgtga
    32161 ggaggctgtc ggatcgttta tcactgtttc agaagaagtt gctcttaaac aagctgcggc
    32221 aattgatgcc aaaggtattg atgctgataa cctcatgtca ggtattccgt tagctgttaa
    32281 ggataatatt tcaaccaagg aaatcctaac cacagccgct tcaaaaatgt tgtataacta
    32341 cgagccgatt tttaatgcca catcagtagc aaatgcctac gctaaagaca tgattgttat
    32401 tggaaaaacc aacatggacg aatttgccat gggtggttca acagaaacct cttatttcaa
    32461 gaaaacgaaa aatgcttggg accacacaaa agtacctgga ggctcatcag gtggttcggc
    32521 aacagcagtc gcttcaggac aagtccgttt atctcttggt tcagacactg gtggttctat
    32581 tcggcagcca gctgcattta atggtgttgt cggtttgaaa ccaacctatg gcactgtttc
    32641 tcgctatggt ctcattgctt ttggaagttc acttgatcag attggacctt ttgctccgac
    32701 agttaaagaa aacgcccaat tattaaatgt gattgcaagt agcgatgtca aggatgccac
    32761 ttcagcgcct gtccgcattg cagactacac atctaagatt ggtcgtgaca ttaaaggcat
    32821 gaagattgcc cttcctaaag agtatcttgg cgaagggatt gatcctgaga ttaaggaaac
    32881 ggttcttgcg tcagttaaac aatttgaagc cttaggagct actgttgagg aagtcagcct
    32941 tccacatagc aagtacggtg tggctgttta ttatattatc gcttcgtcag aagcgtcttc
    33001 aaacttacaa cgttttgatg gcattcgcta tggtttccgt gctgacgatg ctaaaaactt
    33061 ggatgaaatc tatgttaaca ctcgtagcca aggctttggt gatgaggtga aacgtcgtat
    33121 catgcttgga acctttagtt tgtcatcggg ttattatgac gcttatttca aaaaggccgg
    33181 tcaagtgcgc actttgatta ttcaagattt tgacaaggtt tttgcggatt atgatcttat
    33241 tctaggccca acaacaccga cggttgcttt tggcttagac acactcaacc acgatcctgt
    33301 tgccatgtat ttggccgact tattgaccat tccggttaac ttggctggtc tgccaggtat
    33361 ttctattcca gcaggattcg tcgatggctt gccagtaggg cttcaattaa ttggtccgaa
    33421 atacgctgaa gaaaccatct atcaagcagc agcagccttt gaagcggtga cagattatca
    33481 caagcaacaa ccgattattt ttggaggtga caagtaatga attttgaaac cattattggg
    33541 cttgaagtcc atgtggaatt aaataccaat tccaaaattt tctcaccttc gtcagctcac
    33601 tttggtgagg acccaaatgc caacacgaat gtgattgatt ggtctttccc aggggtctta
    33661 ccagtcatga acaaaggggt gattgatgcg ggcataaaag cagcgcttgc ccttaatatg
    33721 gacatccata aagagatgca ctttgaccgc aaaaattatt tctacccaga taatcctaaa
    33781 gcttatcaaa tttcacagtt tgatgagccg attggctaca acggctggat tgatatcaaa
    33841 ctagaagacg gttcaaccaa gaaaattcgt attgaacgcg cacacttgga agaagatgct
    33901 ggtaaaaaca ctcatggcac agatggttat tcttatgtgg accttaaccg ccaaggagtt
    33961 cctttgattg agattgtgtc agaagccgac atgcgttctc ctgaagaagc ctatgcttat
    34021 ttgacagctc tgaaagaaat catccagtat acgggtattt ctgatgtcaa gatggaagaa
    34081 ggctccatgc gtgtggatgc caatatttct cttcgtcctt acgggcaaga acaatttgga
    34141 acaaagaccg aattgaaaaa cttgaactcc ttctcaaatg tccgtaaagg gcttgaattt
    34201 gaggtggaac gtcaagccaa actcttgcgt tcaggtggtg tgatacgcca agaaacgcgc
    34261 cgctatgacg aagcgaataa ggggactatt ttgatgcggg tcaaagaagg ggcagcggac
    34321 tatcgttatt tcccagaacc agacctgcca ttatatgaga ttgatgatgc ttggattgac
    34381 gagatgcgtg ctcaattacc tcaattccca gctcagcgtc gtgctaaata cgaagaggaa
    34441 cttggcctct cagcttatga tgctagccag ctaacagcta ccaaagtctt gtcagatttc
    34501 tttgaaactg cagtaagtct tggtggcgat gccaagcaag tctctaactg gttgcaagga
    34561 gaagttgccc aattcttaaa tgcagaaggc aaaaccattg aagaaatcgc tctgacacca
    34621 gaaaatttgg tggagatgat tgctatcatt gctgatggta caatctcttc taaaatggct
    34681 aagaaggtct ttgtgcattt ggctaaaaac ggtggctcag cacgtgccta cgtcgaaaag
    34741 gcaggacttg ttcagatttc tgatcccgct gttttggtac caattattca ccaagtcttt
    34801 gctgataatg aagctgcagt agctgatttc aaatcaggca aacgtaatgc tgataaggct
    34861 ttcacaggct tcttgatgaa ggcaaccaaa ggtcaagcta atccacaagt cgctcaacaa
    34921 ttattggcac aagaattgca aaaattgcga gattgatagt tgctgatagc aataagttaa
    34981 agtattttgt ctctgaaaaa aaggcggtcg gtctttcaca ggctgccttt ttgtatgtca
    35041 tgttagtgac cgcctataaa aagaccatca tctatgctaa aataagactg acaggtattg
    35101 ctttagaacc ttcaggagtt tctgacgggt atttaatgaa ctatcacgtt tgtctacact
    35161 attattagcg attagctgtg tgataaagtt tgttaagtta tttagtgtgt gaagacttct
    35221 agtcgttctc ggtctatcta tcttaataga aggaattgtt ttttctattt tactcaggca
    35281 cggaaacact tactaaagaa gaaggtaaag gaatcaacta aagttaagaa catttaatgg
    35341 atagcagttc ttctaaaagg attttacaag aaaggaggtg ttaacgatga tatggtcttt
    35401 aattgtaggt gcctttatcg gcatgatagc aggtaaaatg actgaaaaaa gccagtccat
    35461 gggttgtttt actaatatta tcgcaggtct catagggtca gctgttgggc aaaggctttt
    35521 tggggattgg ggaattcagt tggcaggtat ggctattttc ccgtccattt tgggagcagc
    35581 aattgtaatt gtacttgttt cagctatttt tggaaaaagg tattaaaaaa aggctgcatg
    35641 gaagtttcca agcagccttt ttgcaacata aaatgtctta tctttttatt ggttgcatcc
    35701 tcattataag atagttgtgt gaaaatttaa tatcgttttc ttgacaaata gttagatttt
    35761 gttactgttt tgacatcatt ttgtaacgtc agtttagttg tagtgtgggt ctgttgttat
    35821 atatatttga gcgaaataca caaatgtaat cgtttggaaa tttatgtgat gatttgaatt
    35881 gtagcaatag cattgttttt aataaaatag acaataagtc agtggtctat ttgatctcaa
    35941 atagccatca ggaagtgttt tgcaagtgtt ttctttaaat gctataataa ttaataagac
    36001 agtttaggag gttgaaatga caaaaacaag gttgtatatt gccagacatg gaaaaacgat
    36061 gtttaatacc attggtcgcg ctcagggttg gagtgacaca cctcttacaa aaaaaggaga
    36121 agaaggtatt cgagaacttg gcctaggttt aaaagatgca actataccat ttaaggctgc
    36181 gttttcaagt gattcaggtc gaaccatgca gacaatagaa attattttaa gagaatcaga
    36241 aaacgaattt ttgccttata ctaaagataa tcgtattcgt gagtggtgtt ttgggagtct
    36301 agaagggact tatgattcag aattatttct aggtgtcctt ccaagaacaa aagcctttga
    36361 aaatcgtgat aacctacgtg atgttcccta ttctgaactg gcagaaagca tcgtggaagt
    36421 agataccgct aattgggcag aaccatggga agttcttcgt aagcgcattt gggaggggtt
    36481 tgaagctatt gccttgtcta ttcaaaatgc tggcggcgga aatgctcttg tggttagcca
    36541 tggtatgaca attggaacgt ttctgtggtt gattgatcca gatcgagaca aacagtatat
    36601 tgataatggg agcgttacag ttgttgaatt tgatgatggc caatttacga taaagactat
    36661 tggagatatg agttaccgct accgcggtcg tgaaataata gaagaacggt cagatgaaat
    36721 ataattcgtt aaactattta gtgcaattgc taattgttat tgttttttta ggagggcttt
    36781 acctctttat aaaaccagaa gagtcagtaa caccaactca gttgaataaa aaagaaatcc
    36841 aacaaaaaga tatcaaaaaa acggaccgtt tacgagcttt acctaaggta tctgttgaag
    36901 attgggagtt ggttttagta aaccgcgatc acattacaaa agaaatgagt cctgaattag
    36961 ctgacattaa tggtatttct gtggataaac gcattgagca agccactagt gactttttag
    37021 cagcagcaca agctatcgac ttgcaagaac atcttatctc tgggtaccgt tccgtagact
    37081 accaaacaga gctttaccaa tcttatatta aaaaagagat ggctaacgat ccaacattga
    37141 cacaagaagc tgcggaggct ttggtgcaaa cctattcaca gccgccaggg gctagtgaac
    37201 atcacactgg tcttgctatt gacatgagca ctgtagatac tttaaatgcc agtgatccat
    37261 cagtagctaa agcagttcaa aaaattgcac ctgattatgg gtttgtcttg cgctttccag
    37321 aaggaaaaaa gactagtaca ggggttgatt atgaggattg gcattaccgc tatgtaggca
    37381 aggcgtctgc tcgttatatg gctcagcaca acctaacgtt ggaagagtac attgctgctt
    37441 taaaggagaa acgatgagaa aacgactaaa gtttccgtat tttttaacgc ttctagcttg
    37501 ctttttattg ctgattgttt gtcccttact gagtagccaa aggatagcta gtgcagataa
    37561 agaagtaagg gtgaactaca gccaaaaaca atttattaca aaaatgggta aagaagttaa
    37621 accattggca aaatattatg gcattagacc atctattttg attgctcaaa ttcttttgga
    37681 aacccatgat ggaaaaacat tactagcgtc taagtatcat aatcttttta gcaagaaagc
    37741 aactccagga caagtggcca ttaccctaaa gtcccctaaa caaaccaacc aaaacgtgag
    37801 atatgctatt tataaagatg acgctagtgc aattagagat tatttacgaa tgcttcggca
    37861 gggaaaagaa gtcgataagc gtttgtatcg taatcttgct acagaaaaag ggtataaagc
    37921 accagctaaa agtttacaaa agtatttgca ttatactgat aaaacctatg ctaggcgact
    37981 aattcaggtc attgaaagta acgatttaac aaactatgac tgaaattagc gctctttata
    38041 aaagagtgct aatttttttg agtttttttc ttgacatgtc tcccataaag agtataatag
    38101 aattataaat tagcagtcta ctaaatagag tgctaaacga aagggagtgg ttggtttgtg
    38161 attacacaac gtcaaaatga tattttgaat ttaatcgttg agctatttac acaaactcat
    38221 gaaccagtag ggtctaaagc tttacagaga acgattgatt ctagtagcgc cactattcgt
    38281 aatgatatgg caaaactaga gaagttggga ttgttggaaa aagcgcacac ttctagtgga
    38341 cggatgccaa gtccagctgg ttttaagtat tttgtagagc actccctcag gctagatagt
    38401 attgatgagc aagatattta tcatgtcata aaagcttttg attttgaagc attcaaatta
    38461 gaagacatgc ttcaaaaagc tagtcacatt ttagcggaga tgacgggcta tacatccgtt
    38521 attttagatg tggagccagc tcgtcaacgt ttaacagggt ttgatgttgt tcagcttagc
    38581 aaccatgatg ctctagcagt catgacttta gatgaatcta agccagtgac agtgcagttt
    38641 gctattccaa gaaacttttt gacacgtgac ttgatagcat ttaaagctat cgtagaggag
    38701 cgcttgctgg ataatagtgt catagatatt cattataagt tgaggacaga aattcctcag
    38761 atcgttcaaa agtattttgt gactacggat aatgttttac aactatttga ttatgttttt
    38821 tcagagctgt ttttggaaac ggtatttgtt gctggcaagg taaattcttt aacgtattca
    38881 gatctatcaa cgtatcagtt tttggataat gaacagcaag tagcaatttc tttgaggcaa
    38941 agtctgaaag aaggtgagat ggcttctgtc caagtggcag atagtcaaga agccgcactt
    39001 gcagatgtgt cagttttaac tcacaaattt ttgattcctt accgtgggtt tggactcctg
    39061 agtttgattg gtcctattga tatggattat cgtaggtctg ttagtttggt aaacattatt
    39121 ggaaaggtat tggctgctaa attaggtgat tattatcgat acctaaattc taaccattat
    39181 gaagttcact gataatggca gtattcaata agttatttaa aaggaggcac tcagtgtcag
    39241 aagaaattaa aaaagacgat ttacaagaag aagtggaagc cactgaaact gaagagacag
    39301 ttgaggaagt tattgaagaa actcctgaaa aatcagagtt agaacttgca aacgaacgtg
    39361 ctgatgagtt tgaaaataaa tacttgcgag ctcatgcaga aatgcagaat atacagcgtc
    39421 gctctagtga agaacgtcaa caacttcaac gctatcgttc tcaggatctg gcaaaagcaa
    39481 tcttaccatc gcttgacaat ctagaacgtg ccttggctgt tgaagggttg acagatgatg
    39541 ttaaaaaagg tttagaaatg actcgtgata gccttattca agcactaaag gaagaaggcg
    39601 tagaagaagt agaagtcgac tcgtttgacc acaactttca tatggcagtt cagaccctcc
    39661 cagccgatga tgaacatcca gccgatagca ttgcagaagt ctttcaaaag ggatataaat
    39721 tgcacgagcg tctgctaaga ccagcgatgg tagttgttta taactaaggt aaatgagttt
    39781 tcgtttttgt ccgtaatgac agtaaactag atagcaagtt agaagctatt tcgcttgctg
    39841 attaaactat agtgattgct tagaattgga agtaaaataa ttcgagtgct tactaagata
    39901 aattgaaata aaaagtaata aagtattata aaataagagg tattaacatg tctaaaatta
    39961 ttggtattga cttaggtaca acaaactcag cagtagcagt tcttgaaggg actgaatcaa
    40021 aaatcattgc taacccagaa ggcaatcgta caactccttc agtagtatca ttcaaaaatg
    40081 gtgaaattat cgtgggtgat gctgcaaaac gtcaagcagt gacaaaccca gaaacagtaa
    40141 tctctattaa atctaaaatg ggaacttctg aaaaagtttc tgcaaatggt aaagaatata
    40201 ctcctcaaga aatttcagca atgattcttc aataccttaa aggttatgct gaagactatc
    40261 ttggagaaaa agtagaaaaa gcagttatta ctgttccagc ttacttcaac gatgcacaac
    40321 gtcaggcaac taaagacgct ggtaaaattg caggtcttga agtagaacgt atcgttaacg
    40381 aaccaacagc agccgcactt gcttatggta tggataagac tgacaaggat gaaaaaatct
    40441 tagtttttga ccttggtggt ggtacatttg acgtatcaat ccttgaatta ggtgatggtg
    40501 tcttcgacgt tcttgcaaca gcaggtgata acaaacttgg tggtgacgac tttgaccaaa
    40561 aaattattga tttcttagtg gctgaattta agaaagaaaa tggcattgac ttatcacaag
    40621 ataagatggc acttcaacgc ttgaaagatg ctgctgaaaa agctaaaaaa gatctttcag
    40681 gtgtgacaca aacacaaatt tcattaccgt tcatcactgc tggttctgcc ggtcctcttc
    40741 acttggagat gagcttatct cgtgctaaat ttgacgatct cactcgcgac cttgtagaac
    40801 gtacgaaaac tccagttcgt caagcccttt cagatgcagg attgtcattg tcagaaattg
    40861 atgaagttat ccttgttggt ggatcaactc gtatcccagc agttgtcgaa gctgtaaaag
    40921 ctgaaactgg taaagaacca aataaatctg taaaccctga tgaagtggtt gctatgggtg
    40981 ctgctatcca aggtggtgtt atcactgggg atgtgaaaga cgttgtcctt cttgacgtaa
    41041 caccattgtc acttggtatt gaaacaatgg gtggtgtctt cactaaattg atcgaccgca
    41101 atacaactat cccaacatct aaatcacaag tcttctcaac agcagcagac aaccaaccag
    41161 ctgttgatat ccatgttctt caaggtgaac gcccaatggc agcagataac aagactcttg
    41221 gtcgcttcca attgactgat atcccagctg cacctcgtgg aatcccacaa attgaagtaa
    41281 catttgatat cgataaaaac ggtattgttt ctgtaaaagc taaagacctt ggtacgcaaa
    41341 aggaacaaca catcgttatc aaatcaaacg acggactttc tgaagaagaa attgatcgca
    41401 tgatgaaaga cgctgaagct aatgccgaag ccgatgcgaa acgtaaagaa gaagttgacc
    41461 ttaaaaacga agttgaccaa gctatctttg ctactgaaaa aacaatcaaa gaaactgaag
    41521 gtaaaggctt tgatacagaa cgcgatgcag cgcaatcagc tcttgacgag ttaaaagctg
    41581 cgcaagaatc tggcaacctt gacgacatga aagctaaact tgaagcatta aatgaaaaag
    41641 cgcaagcttt ggctgttaaa atgtacgagc aagctgcagc agctcaacaa gcagcacaag
    41701 gtgcagaagg tgcacaagct aatgattcag caaataatga tgatgttgta gatggcgaat
    41761 ttacagaaaa gtaatgattt agttatctag taacattaat atccgaattc agaggttgta
    41821 ccaaacctct gtttttggct aaataaaatg taaaaatgct gacgtcaaaa tattttaaga
    41881 aaggaataca agttcgatta ttcgaacaca ggctaaagcg tgtaaagact cttttgcgga
    41941 tttgaacacg cctacgactc tgcgaaaaaa gagaaatacc tcctagatac gagagtatct
    42001 ttgtcggatt tcctattttt cattaagtcg ttttacagct tggtatctta cattatgaac
    42061 aatacagaat attacgatcg tctgggggtt tctaaggacg cttctcagga cgatatcaaa
    42121 aaagcttatc gaaaaatgtc taaaaaatat catccagata tcaataaaga agctggagcg
    42181 gagcaaaagt ataaggatgt tcaagaagct tacgaaacct taagtgattc acaaaagcgt
    42241 gctgcttatg atcaatacgg cgctgcaggt gctcaaggcg gctttggtgg cggagcaggc
    42301 ggctttggtg gttttgacgg aggtggcttt ggtggttttg aagatatctt ctcaagcttc
    42361 tttggtggcg gtggaagccg aaacccaaat gcccctcgtc aaggtgacga tttgcaatat
    42421 cgtgttaatt tatcttttga agaggctgta tttggtgttg aaaaagaagt tagctataat
    42481 cgcgaagcaa cctgcggcac ttgtttaggc tcaggtgcaa aacctggtac cgctccagta
    42541 acttgtcgta agtgccatgg ttcaggtgta atgacaattg acacccaaac accacttggt
    42601 atgatgcgtc gacaagtcac ctgcgatatt tgtcatggta gtggtaagga aattaaagaa
    42661 ccctgtcaaa cctgtcacgg tactggtcat gaaaagcaag ctcataaagt gtctgttaag
    42721 attccagctg gtgtagagac tggtcagcaa atccgtttac aaggtcaagg agaagctggc
    42781 tttaatggcg gaccttatgg tgatttattt gttattttga atgtcttacc aagtaagcaa
    42841 tttgaacgca atggttccac tatttactac aacttagata tttcttttac tcaagcagcc
    42901 ttaggagata ctgttgaaat tccaacggtt catggcgatg ttgagatggc tatccctgct
    42961 gggacacaaa caggtaaaac cttccgcctc aaaggcaaag gagcaccaaa actccgtggt
    43021 ggaggtcaag gggatcaaca tgttaccgtt aatattgtga ccccaaccaa actcaatgac
    43081 gctcaaaggg aagccttgca agcatttgca gaagcgagtg gtgaaaaaat gttacatcca
    43141 aagaaaaaag gtttttttga taaagtgaaa gatgccttag aggatattta aagatgtcaa
    43201 acgtataatt tcaggataat tttcccgaag ttatacgttt ttttacgtca aaacagttag
    43261 agaaaacgtt ttcttttata gatatcgttt ttttctcttg tcaaaatggt ttatttagta
    43321 tatcataatt aggtaattga tttgattatc aaatgatttt aaagagaaat aatttcttag
    43381 tcaaataaat tatcagaaaa gaggattgtt atgcagttta aacacatcat ctttgatgtt
    43441 gtagatgatc ttgcgacatt gactttaaac cgtccagagg tttcaaacgg ttttaatatt
    43501 ccaatttgtc aagagattct ggtagcatta gcagaagtta aacgcgatac atctgtgcgt
    43561 tttttattaa ttaaagccgt tggaaaagtg ttttcagttg gtggtgacct agttgaaatg
    43621 caagaagctg ttgcaaaaga taatgtgcag tcgctagtca agattgctga actggtacaa
    43681 gaaatttctt ttgcaataaa gcatttgcca aaaccagtca tcctttgcgc cgatggagct
    43741 gtagctggag cggcttttaa tatagcttta gctgttgact tttgtatcgc tagtactcaa
    43801 acaaaattta tccaagcttt tgtaaatgtt ggactagcac cggatgccgg tggtttattt
    43861 ctattgactc gtgcagtagg acttaatcgt gcaactcacc ttgtgatgac aggtgaagga
    43921 attactgctg ataaaggtct cgattatggg tttgtctacc gtacggcaga atctgataaa
    43981 ctagacaaag tttgtcttca acttttaaag cgattgagac gtggctcttc aaattcttat
    44041 gctggaatga aatcattggt ctggcaaagt tttttcacag gatgggaaga ttatgctaag
    44101 gcagagcttg ctattcaaga ggagctagct ttcaaggaag attttaaaga aggtgtcata
    44161 gcttttggag aaaggcgccg accaaatttt caaggtaagt aagacagcta ttgcttgcaa
    44221 aatactttga cctttgatat aatttgattg tcaaagttta ttgctaggag gtgtttactt
    44281 ggaatatgac aaaattaacc aatacttagt tgatattttc aaccggattt tggttattga
    44341 agaaatgagc ttaaagacga gtcagtttag tgatgtctct ttaaaagaga tgcacactat
    44401 tgaaattatc ggcaaatatg atcaggtgac tccaagtgat atcgccagag aattaatggt
    44461 aacgttaggg acagtaacca ctagcttaaa taaattagaa gcaaaaggtt atatcgcaag
    44521 aacgcgatca cgctcagata ggcgagttgt ttacctgtca ttaacaaaaa ggggtcgact
    44581 tttggaccgc ctccatgcaa agttccataa aaatatggtt ggacatgtca ttgctgatat
    44641 gagtgatgaa gagatgcagg cattggtgcg tggactaggg aatctacatc aatttttgga
    44701 ggatttggtt taaatgattt tttctaaaat cagtcaggta gcccactatg ttccacagca
    44761 gttagtgact aataatgatt tagctagcat aatggacact agtcatgagt ggatcttttc
    44821 tcgaacagga atagcagaac gccatatttc tagagatgaa atgactagtg acctagctat
    44881 tcaggttgct gatcagcttt taactcagtc tgggttaaaa gctgatgcta ttgattttat
    44941 tattgttgca actatcagcc ctgatgccac tatgccatca acagctgcga aagttcaagc
    45001 agctattgcg gctacaagtg cttttgcttt tgatatgact gctgcttgta gtggctttgt
    45061 ctttgccttg gctatggcag ataagcttat tgcatcaggt gcctaccaaa acggaatggt
    45121 aataggtgca gagactttat ctaagttagt aaactggcag gatcgagcga cagccgttct
    45181 ttttggagac ggagctggtg gcgtgctact ggaagccagt aaagataagc atgttttagc
    45241 ggaaacatta cacacagatg gtgcgagatg tcagagtttg atttcaggag aaactagtct
    45301 ttcatctcct tactcaattg gcaaaaaagc catagcgact attcagatgg atggacgtgc
    45361 catatttgat tttgcgatta gggatgtgtc aaaaagcatc ctcacactaa tggcgcaatc
    45421 agatattaca aaagatgaca tagactattg tttattgcat caagctaatc gtcgtatact
    45481 tgataaaata gcacgcaaga ttgatgttcc tcgggaaaaa ttccttgaaa acatgatgcg
    45541 ttatggtaat actagtgctg ctagtatccc aatcctcttg tcagaggctg ttcaaaaggg
    45601 acagattagg ttagatggta cccaaaaaat cttactttcc ggttttggtg gaggtttgac
    45661 atggggaagt ctaattgtta gaatctagtt attcatgtgc ctagcacatt tataaaaaca
    45721 aatttatatt ttttaaggag aaataaacat ggcagtattt gaaaaagtac aagaaattat
    45781 tgttgaagaa cttggtaagg agacagaaga agtaacacta gaaactacat ttgatgattt
    45841 agatgcagat tcacttgatg ttttccaagt tatttcagaa attgaagatg cttttgatat
    45901 tcaaattgaa acagaagaag gattaaatac tgttggtgac cttgttgctt acgttgaaga
    45961 aaagtcaaaa taaggataaa agtgacaagt aacatcagaa gtctatgaaa agcttactgc
    46021 tgttatgttc atgttcatca ctaaaaaaaa caataagtat taatcaaacc attagggtgg
    46081 gattagactc tttttaggat ctagctcgct ctttcttctt actataatag tttgattatc
    46141 aaattattct ccttattttt tatagaaagt tattatgaaa acacgtatta cagaattact
    46201 taatattgat taccccattt ttcaaggagg aatggcttgg gttgctgatg gtgatttagc
    46261 aggtgcagtt tctaatgctg gtggtttagg cattataggt ggtggcaatg ctcccaaaga
    46321 agtcgttaaa gctaatattg atcgtgtcaa agctattact gatagacctt ttggggttaa
    46381 tatcatgctt ttatctcctt ttgctgatga tatcgttgat ctggtcattg aagaaggtgt
    46441 taaagtagta acaacaggcg caggaaatcc aggaaagtat atggaaagac tgcaccaggc
    46501 gggtataatc gttgttcctg ttgtcccaag cgttgcgcta gccaaacgta tggaaaagct
    46561 tggggtagat gctgttattg ctgagggtat ggaagctgga ggacatattg gcaagttaac
    46621 gactatgtct ttagtaagac aagttgttga agcggtttcg attcctgtca ttgcggcagg
    46681 tggtatagct gatggtcatg gtgcagcagc agcatttatg ttaggagcag aggctgttca
    46741 aattggaact cgctttgttg ttgctaaaga atccaatgct caccaaaatt ttaaagataa
    46801 aatcttagca gcaaaagata ttgatacggt gatttctgcg caggttgtgg gccaccctgt
    46861 ccgttctatt aaaaataaat tgacctcagc ttacgctaaa gcagaaaaag catttttaat
    46921 tggtcaaaaa acagctactg atattgaaga aatgggagca ggatcgcttc gacacgctgt
    46981 tattgaaggc gatgtagtca atggatctgt tatggctggc caaattgcag ggcttgtgag
    47041 aaaagaagaa agctgtgaaa cgattttaaa agatatttat tatggtgcag ctcgtgttat
    47101 tcaaaatgaa gctaagcgct ggcaatctgt ttcaatagaa aagtagataa acacatgaag
    47161 gataatgata atgacaaaga cagccttttt atttgccggt caaggtgctc aaaaattagg
    47221 gatggcaagg gatttttatg ataactttgc tattgtaaga aaaacctttg atcaagctag
    47281 tcaagtattg ggatacgatt tgcgccgttt gattgatagt gacgagttaa aacttaatca
    47341 aactagctat acgcaaccag ctattttgac atcatcaatt gctatttacc gtgttttggg
    47401 cttacatcac gttaaaccgg atatggtagc tggtctttcc ttaggagaat actcagcttt
    47461 ggtagcatca ggggcactct cttttgaaga taccctatcc ttagtagcta agagaggccg
    47521 cttgatggag gaagcagcac cacaaggatc tggaaagatg gttgccgtta tgaatacaga
    47581 cgtgcaagtc atcgaagaag tctgtcaaat agctgctaaa catggagtgg ttgctccagc
    47641 aaactataat actcctagtc aaattgtaat tggtggtcag acagatgctg tgaacgtggc
    47701 agttgaactt ttaaaggaaa ggggagttaa gcgtttaatc cctttaaacg tgtcaggtcc
    47761 tttccacact gctttgttag aaccagctag ccgcttgttg gctaaagagt tggaaagata
    47821 caacttcagt gacttcaaga ttcctttggt tggtaatacc gaagctaata ttatggaaaa
    47881 agaccgtatc ccagaactat tagcccgtca agtcatggag cctgttcgtt tttatgacag
    47941 tgttgcgact ttagtagaaa gtggcataac acaattcatt gaggtaggac caggtaaggt
    48001 tttgacaggt tttgtgaaga aaattgataa aaatttacta tgtactagtg ttgaaaacat
    48061 ggtaagctta cgtttatttt tagatagaga ggacattcat ggaaattaaa ggaaaaaata
    48121 tatttatcac aggctcaacg agaggtatcg gtttagcaat ggctcatcaa ttcgccagtt
    48181 taggagctaa tattgtctta aatggtcgct ctgctatctc tgaggagctt gttgctagtt
    48241 ttactgacta cggcgttaca gttgttacca tctctgggga tgtttcagaa gcatcagaag
    48301 ctaaacgtat ggtcaatgaa gctatcgaaa gtttaggttc gattgatgtt ttagttaaca
    48361 atgctggcat tactaatgat aaattgatgc ttaaaatgac ggaagaggat tttgagcgcg
    48421 tcttgaaaat caatttgacc ggtgctttta acatgactca atcagtgtta aaaccaatga
    48481 tcaaggcccg ccaaggagca attattaatg tctctagtgt ggttggttta acaggcaata
    48541 ttgggcaagc aaactatgct gcttctaagg caggaatgat tggttttacc aagtctgttg
    48601 cccgtgaagt tgctgctcgt aacatttgcg tgaatgctat tgctccagga tttatcgagt
    48661 ccgacatgac aggtgtcctt cctgaaaaaa tgcaagagca aatcttaagt caaatcccaa
    48721 tgaaacgtat tggaaaagct caagaagttg ctcacttagc aagcttcttg gtggaacaag
    48781 attatattac gggacaagtt atcgctattg atggcggtat gacaatgcaa taaggagacg
    48841 tagtgaaatg acatttaaaa gagtagtggt aacaggttat ggtctaacat ctccaatcgg
    48901 gcatgatcct gaaacgtttt ggaacaatct gaaagctggc caaattggta ttggtcctat
    48961 tactaaattt gacacgactg attatgcagt caagaatgct gctgaaattc aggattttcc
    49021 atttgacaaa tactttgtga aaaaagattt gaaccgtttc gatagatatt ctctttatgc
    49081 tctttacgca gcgaaagagg ctattaatca tgctgattta aatattgaga tggttgattc
    49141 cgatcgattt ggcgttattg ttgcttcagg tattggtgga attgcggaga ttgaagagca
    49201 agtgattcgc ttacatgaaa aagggccaaa acgtgtgaag ccaatgacgt tgccaaaagc
    49261 gctaccaaat atggctgcag gaaatgtcgc catgtcttta aaagctcaag gagtatgtaa
    49321 atcaattaat actgcctgcg cttcttcaaa tgatgcgatt ggggatgcct ttcgtgccat
    49381 taaatttggg actcaagatg tgatgatagt tggtgggtca gaggcggcca taaccaagtt
    49441 tgccattgct ggcttccaaa gtttaacagc tctctcaaca actgaagatc caagcagaag
    49501 ctctattcca tttgataaag accgcaatgg ttttatcatg ggagaaggat caggaatgct
    49561 tgttttagaa agcctagaac atgcgcaaga acgcggggcg acaatcttag cagaaattgt
    49621 gggttatgga aatacctgcg atgcctacca tatgacatct ccaaatcctg agggattagg
    49681 agctcgtaaa gccatccact tagccttaca agaagctggt attgaagcca gtgctattaa
    49741 ttatgtcaat gcgcacggaa cttcaacccc agctaatgaa aaaggagaga gtcaagcaat
    49801 tgtagccgtt cttggtaagg atgttccggt gtcttcaaca aaatcgttta cgggtcacct
    49861 tcttggagca gcaggcgcta ttgaagctat tgccactatc gaggctatgc gtcataacta
    49921 tgttccgatg acggctggga cacaagcttt atcagaggat atcgaagcaa atgtcatctt
    49981 tggagaagga aaagaaacag ctatcaacta tgccatttca aatacttttg gatttggtgg
    50041 tcataatgct gtattagctt tcaaatgttg ggaggagtag gttgaatatt caagaaatca
    50101 aagatttgat ggctcagttt gatacctcaa gcctacgtga atttttattc aaaacaaatg
    50161 aaggtgagct aatctttagt aaaaacgaac aacacctcaa tgcatcgaca tcaaatcaag
    50221 aacatgctgt gcctgtacca caggtacaac ttgttccgaa tccaactgct tcggaagcgt
    50281 ccagtccagc atcagttaag gatgttcctg tagaggagca accacaagca gaatcttttg
    50341 tagcagaagg tgatattgtt gaaagtcctt tagtcggtgt agcctatctt gcagctagcc
    50401 ctgacaagcc accatttgtg gcagtcggag atactgtaaa aaaaggacaa acccttgtga
    50461 ttatcgaagc catgaaggtg atgaacgaag tgccagcgcc atgtgatggt gtgattacag
    50521 aaattttggt atcaaatgaa gatgtcattg aatttggaca aggattggtg cggatcaaat
    50581 gatggatatt agagaaattc aagcggcttt gcctcatcgc tacccaatgt tattggttga
    50641 tcgtgtgtta gaagtgtcag acgaccatat cgttgccatt aaaaatgtga ctattaatga
    50701 gcctttcttt aacgggcatt ttcctcacta tcctgtgatg ccaggtgttc tgattatgga
    50761 agctttggct caaacagctg gtgtcttaga attgtcaaaa gaagaaaata aaggcaagtt
    50821 ggtcttttac gctggaatgg ataaagtgaa gttcaaaaaa caagtcgtcc ctggtgatca
    50881 acttgtgatg acagcaacct ttatcaagcg tcgcggtacc attgctgtcg ttgaagccag
    50941 ggcagaagtt gatggcaagc tagcagcaag tggaacatta acctttgcct gtgggcaatg
    51001 agaatgattg ttctgcggag gaagaaaccc ttatgtttaa aaaaatctta attgctaatc
    51061 gtggtgaaat tgcagtgcgt atcattcgtg ctgcacgaga attagggatt tccacagttg
    51121 cagtttattc ggaagcggat aaggaagctc tgcacacgat cttggcggac gaggctatct
    51181 gtattggtcc tgcccgttcc aaggaatcct atcttaatat gaattccgtc ttgtcagcag
    51241 ctattgtgac aggagcccaa gcgattcacc cagggtttgg ctttttaagt gaaaactcaa
    51301 agtttgcgac catgtgtgaa gagatgaata ttaaatttat cggtccatcc gcatcggtta
    51361 tggataaaat gggtgataaa atcaatgctc gttctgaaat gattaaggca ggagtgcccg
    51421 ttattccagg gtcagatggt gaagtttata acgctcaaga agccttagct attgccaata
    51481 agattggtta tcctgtcatg ctaaaagcat cggcaggtgg tggaggtaaa gggattcgta
    51541 aagtggagac agaagcagat ttggaggcgg ctttcaatgc tgccagtcaa gaagctttgg
    51601 gagctttcgg aaatggcgcc atgtatttgg aaaaagtaat ttatccagct agacatattg
    51661 aggtgcaaat tttaggagac gcttacggta acatcattca cttgggagaa cgggattgct
    51721 ccttgcaacg gaataatcaa aaagtcttgg aagaaagtcc atccattgct attggcaata
    51781 ccctcagaca cgaaatgggg caagcagcgg ttagagcagc tgaagctgta gcctatgaaa
    51841 atgcgggaac cattgagttt ttgttggacg aagacagcga gaaattctat ttcatggaaa
    51901 tgaatacccg tatccaagtt gagcatcctg tcaccgaatt tgtgacagga gtggatattg
    51961 tcaaagagca aatcaaaatt gcagcaggtc agcctttggc gattaatcaa gaagacatca
    52021 ctatcacggg acatgctatt gaatgtcgta tcaatgctga aaatactgct tttaactttg
    52081 caccgagtcc aggaaagatt acagacttgt atatgccaag tggtggtgta ggactacgag
    52141 ttgattcagc agtttacaat ggctatgcca ttcctcctta ttatgacagc atgattgcta
    52201 aaatcatcgt tcatggaagc aatcgatttg acgctttgat gaaaatgcaa cgtgccttag
    52261 ttgaattgga aattgaaggc attatcacca atacagactt ccagctcgat ttgatttcag
    52321 ataagcgagt gattgcagga gattatgata cctctttctt gatggaaacg ttcctgccac
    52381 attacaataa agattaggag aaaatatggc tttatttcgt aaaaaagata aatacatccg
    52441 tattactccc aataattccc tcaaaggatc tgtcagccat aatgtcccag aagttccaga
    52501 tgaactcttt gcgaaatgcc cagcttgtaa gcacatgatt tataagaaag atttgggatt
    52561 ggcaaagatt tgcccaacct gttcttacaa ttttaggatt tctgcccaag agcggctgac
    52621 cttaacagtt gatgaaggct ctttccaaga attatttaca agtattgaaa ccaaggatcc
    52681 gttacgtttt ccaggttatc aggaaaaatt acaaaaagcc aaggaaacga caggtctgca
    52741 tgaagctgtt ttgacaggga aagctatggt taaggagcaa aagattgctc ttgctattat
    52801 ggattctcac tttattatgg ctagtatggg aactgttgtt ggggaaaaaa ttacccgatt
    52861 gtttgaattg gctatcgaag aaaacctgcc ggtggtgatt tttacggctt caggaggcgc
    52921 ccgtatgcaa gagggtatca tgagcctcat gcaaatggcc aaggtctctg cagctgtgaa
    52981 aagacattct aatgcaggcc tcttttacct cactattttg acagatccaa ctactggtgg
    53041 ggtaacagct agttttgcca tggaagggga tattattttg gcagaacctc aatccttggt
    53101 tggctttgca ggtcgtcgtg tcattgagac cacagttcgt gaaaacttgc cagatgattt
    53161 ccaaaaagca gaatttttac aagaccatgg ttttgtggat gctattgtga aacgaacaga
    53221 gttgcgagac aagattgccc acttagtagc atttcatgga ggtggccaat gacagatgta
    53281 tcaagaattt taaaagaagc gcgtgatcaa gggcgtttaa caactttgga ttacgccaac
    53341 cttattttcg atgactttat ggaactgcat ggcgatcgcc atttttcaga tgatggtgcc
    53401 attgtaggtg gcctagctta tttggcggga caacctgtta cggtcattgg tattcaaaaa
    53461 ggtaagaatt tacaggataa tttggcaagg aattttggcc agcccaatcc agaaggttat
    53521 cgtaaagctt tgcgccttat gaaacaggca gaaaaatttg gacgaccagt tgttacgttt
    53581 atcaatactg caggagccta tccaggtgtc ggtgcggaag aacgaggaca gggtgaggcc
    53641 attgctaaaa atttgatgga aatgagtgat ctcaaggttc ccattatcgc catcattatt
    53701 ggtgaaggag gctctggtgg tgcattagcc ttagcggttg ccgatcaggt ctggatgctt
    53761 gaaaatacta tgtatgcggt tcttagccca gaaggctttg cttctatttt atggaaggat
    53821 ggttcaaggg cgaccgaggc cgctgaattg atgaaaatca cagcgggtga actctacaaa
    53881 atgggaatag tagaccgtat tattccagaa catggttatt tttcaagtga aatcgttgac
    53941 atcatcaaag ctaacctcat cgaacaaata accagtttgc aagctaagcc attagaccaa
    54001 ttattagatg agcgctacca acgctttcgt aaatattaac aacatccttt tggagtctcc
    54061 ctacgtgaag ggaggccttt ccaaaagggt ttttaactag tcttgtaaat aaggaaatgg
    54121 gtatactaat aagacttttg ataaactagt gtgaagaaaa gtgttgttaa aggggcaatg
    54181 tagtgagttt caagtgatgt ggtggctctt taaaatagta aaccccagaa atcactttaa
    54241 tgatctctgg ggtgaattta ttatttaggt gaaatgacgg tttcgccacc catgtaaggg
    54301 cggagtactt cagggatggt aacagaacca tcttcatttt ggtagttttc taaaatggct
    54361 gctacggtac gaccgacagc aagtcctgac ccattaaggg tgtggagaag tttgacctta
    54421 ccgtcagcct catcacggta acggatttga gcacgacgtg cttggaaatc ttctgtattt
    54481 gaacatgatg aaatttcacg ataggtattt tgagctggaa tccagacttc aaggtcatag
    54541 gttttagcag ctgagaagcc catgtctcca gtacaaaggg aaatgacgcg atatggcaaa
    54601 ccaagttttt gaagaatatt ttcagcatta gcagtcattt tttctagttc ttggtaagat
    54661 tcttctggtt tagcaaattt aaccatttca actttgtgga attggtgtag gcggataagg
    54721 ccacgtgtgt cacgacccgc agaacccgct tcagaacgaa aagatgggct cattgcagta
    54781 aagtaaattg gcaattcttt gccgtctagg atttccccac ggtaataatt ggtcaaaggc
    54841 acttcagcag ttggaatcag gacaaagttg gtatcagcta attcaaaggt gtcctctttg
    54901 aattttggat attgtcctgt accaaacatg gaatcgtggt taaccatgta aggtgtgatg
    54961 atttcttgat aaccttcttt gatatgttca tccagcatga agttataaag agcacgctcc
    55021 aaacgagcac caagattttt atagaataag aaacgagcac cagttacctt tgccccacgt
    55081 tcccagtcta aaatatcaag atcttcgcct agatcccaat gagccttaac ttcgaagtca
    55141 aagtcacgag gcgttcccca acggcgaatt tcgacattgt cttcttcgtc agctccaaca
    55201 gggacagaat cgtgaggagt attaggtaaa acagtgatga tgtcagtaac ttgctggtcg
    55261 atagctacta gttgattgtc aatagttttg atatctgcag agactttttg catatcggca
    55321 atttgttgag tggcatcttc tttttgacgt tttgcttggg cgatggctgc agaagcaata
    55381 ttacgctctg cttttaattc ttctgattgc actaatagag cacgacgttt ttcatcaagt
    55441 tctttaagat gggtcagggt gtcttcagaa acaccgcggt tttttaattt ggcagcgaca
    55501 gtgtcaaaat cggtacggat acgtttaaga tctagcatac agaagctcct ttaagatagt
    55561 tattagtagc tgtcagtgaa acaaggctaa gtaagacagt tgggtcttgt gattctctga
    55621 cgatagaaaa agcacagctt atgaagatgc tggagcgctt tggcgcggtt ccatccagct
    55681 tcacaatctg tgcacttaat ctctatttta ttgatgacac ggtagaattt catatcattt
    55741 tccctatctg ttcacagcat ccacagactc tctgaatgaa aaaaaggtat tacttatccg
    55801 ttaggactat tataacaaaa aacaagaaaa agtaaactca aatgagggaa tcttttccac
    55861 taaatagcaa gttagagcta ctattctttg ctttcttgaa atgataaatc ggcactgctc
    55921 attatttttt taatgtcgaa aaaatttgtt aataaaggtt tgcatcaagg ttggtaatgt
    55981 aatcactttc tcattaccaa tatgttgacg agtgattttt aagatttttc cagagtctcc
    56041 agaagcaaat aaaaacttgc cttggtccgt aaaaatttca aagtggcggc taactttttt
    56101 tcttgaaaca ttagccccga tgtgattgat agctgtccaa ggaatttgaa tataatcatt
    56161 cacattttta tcgttgtaaa attcaagggc cttgtcaccg agtaaaatat gaccaacttt
    56221 gcctcccatt ccaaggtagg agacagcttt tgtcttgtat tcgacactag tgtttaaaga
    56281 ttgagccatt taagttcctt tcattgcgta gttgtagtta ttataccata ttttaagtgg
    56341 gattttcctg acataaagca taaaaaagaa gcctgagttc atctcagact tccattggtt
    56401 gattacataa tacctgcaag gtgagcaagg ataccaaatg caaacaagcc gatgatgatt
    56461 gcgattggag aaactttttt cttcaataac cacatgcaaa ggaatgtaag gagtaatcca
    56521 gctaaacctg ggataagaga gtccaattgt ccttgaaggg tttgagcttg gactttatca
    56581 aggctcatac caccaatagc gttggcaagg atagttttca attcagcacc tttaacagcg
    56641 ccatctggga agaccacata ggcaccatct gacaattgtt ttccaggaag gtcgatagta
    56701 aagttgatag atacccaacg ttgaacaagc actgcaagga taaacattcc aaggattgaa
    56761 gcacctttag taatgtcttg gaggataccg cctgacatgt ctttagtaat ttcagaacca
    56821 gctttgtaac caaattcttg agtataccat aagaaggcca tacggataag gttccatcca
    56881 aagaagaaca gaagtggacc aacgatgtta cctgttgaag ccaaagaagc accaagtgcc
    56941 ccaaggatag gacgaatcgt aaaccagaat actgggtcac cgataccagc aagaggtccc
    57001 atcataccga ttttaacccc ttggatagcc ttgtcatcaa ttggcgtacc atttgcgcgt
    57061 tcttcttcaa gggcaagtgt tacaccaatg attggagctg caacgtatgg gtgagtgtta
    57121 aagaattcca tgtggcgctc aagagcagct gcacggtctt caggagacgt atacaatttt
    57181 ttaagagcag ggataagtgc ataagcccag cccatgtttt gcatacgttc gtagttccaa
    57241 gaaccttgta agaattgtga acgccaccaa acacgttgac ggtctgattt agttaattta
    57301 atttgttcag tcatttgttc ttaccccttt ctagtagtct tctaagatgt cgccgattgg
    57361 atcagctgaa cctgctgcat taccaccgtt accacctttt ttagaaagat taaggtagat
    57421 gaaggcaatt gctacaccga taacacccat agcgataagg gttaattggc tgatagctgc
    57481 aagagcaaaa cctagggcga agaatggcca tacttcacga gtagccatca tgttgataac
    57541 catagcataa cctacagcaa caaccatcgc accaccgatt tgcatacctt cgttcaacca
    57601 gtttggcata gcattcaaaa cagattgtac ggctgaagta ggaacagcaa caagaagagc
    57661 tgcagggaca gcgatacgca atccttgaag aagaagggca ataaagtgga agcgttcaat
    57721 acctgcgaaa ttaccttcag cggcagcttt gtcaccagcg tgtacaaggg cagttgacaa
    57781 agtacgaacg atcattgtaa ggaaaagacc agcaacagca agtgggatag ctgttgagta
    57841 agcaaaggta attccttttt gagtaaagtc gccacttttg accatgatga tagcagctgc
    57901 aacagaggca agggcagcat caggggcaac ggcagcaccg atgtttgccc aaccaagagc
    57961 aagcatttga agtgtaccac caaggatgac accagcttca aggtgtccag ttacaagtcc
    58021 aatcaaagta caggcaacaa gtggttggtg catttgaaat tggtcgagga taccttcaag
    58081 accagcgaag aaggcaatga taacgaccaa aattgcagaa ataatcgaaa tatctgacat
    58141 gttgtaatcc tttcaaagta tagtaaacga ggactttttg ctaataagtt agctagtcat
    58201 cgttttaaaa ccttatagcg tttgaaactt atttaatgtt agctttttgg ataagctcaa
    58261 ataagttttt cttagaatcg ttaggaactt tacggacgtc gaatgtaaca cctaggtcgc
    58321 gtaatttttc aaaagtagca acgtcttctt tgtccattga taaaacgttg ttaaccattg
    58381 ttttaccagt tgagtgagcc attgaaccaa cgttcaattc gttgatttca acaccacctt
    58441 caaccgctcg aagggcatct tgaggggttt ggaaaagaat aagtgcgtgt gtgttaccaa
    58501 aacgaggatc tttagaagct tcaatcaatt tgctaattgg aacaacgtta gctttgacac
    58561 caccaggtgc agcctgtttg atcaattgtt tgcgaaggtc atcttgagca acctcatcag
    58621 aagcaacaat gatacggtca gccttagaag ctggagtcca tgctgttgca acttgaccgt
    58681 gtaaaagacg agtgtcaaca cgagcaagat tgatctttaa tttaccatct ccgatgacag
    58741 ttccagcagg aatagctcct tgaagtgcgt taacaacttt ttcagttgca gcagtttctt
    58801 caactgggtt aaggtcttca ggaagggctt tgataccgtc cttagattcc ttaatgatgt
    58861 ttgcagcaac ttgttcaaca cctgcaccag catccataag acgttcagtg taagcttgaa
    58921 taagcatagg caagttgaga ccagtgatga tcgccatttt gcggtcagga ttttcacctg
    58981 ccacacgact agcttggtta aatggagaac cactccaaag gtcagctagc acaaggattt
    59041 catcatcagc atcaaattgt tggatagcat tgttgaagtg tccatacaaa tcatctggtc
    59101 cttcgtttgg catgaaagta acaacttgaa ctttctcttg ttcaccaaaa atcatagaac
    59161 cagattgatg aataccttca gcaaatttac catggctggc aataataata ccgataccca
    59221 ttcttgttct tcctccttta aaatattttt cgttgaaatg aagaagaata atctccttcc
    59281 aaaactaaat tttggcaatt ctttttcact taaacgaaat tcaagaacgt ttctatttta
    59341 aaacgttttc actaaaaaat caagcccttt cggaaaaata gtacaaaaca tgaaaaaatt
    59401 ttcagaattt aggattaaat aggcagatta ttgatattaa aggtgttttc aagctgttta
    59461 aaacaaaaat atgctgaaaa atgttgaaat tattaaaatg attttcattt tttgatagct
    59521 gttgacagaa gaagaaccac cattttctga aaaatagtgg tttcgtttgc tactacaaga
    59581 aaagttcttc caattttttg gcaacaccgt cttcttcgtt ggaaaaatta agctgctgat
    59641 cagcataagg cagtagcaca gggctagcat ttttcatagc ataaccagtt ccagcaaaag
    59701 ctagcatctc agtgtcattg tgttcatcac caaaggcgat taaatccttt ttatccatat
    59761 tgtaaattcc aaggagatag ttcagagcgt aagctttatt gacattctta gacgaaattt
    59821 caagaatgtt gagagggcct ccccaagaat caatttcaat ttcatctttg aagcaagcac
    59881 gcatgttttt agctaaggca tacttgtctt cgtgatgcgt ttgcatcaat aaggcgtttg
    59941 gatttcgagt gattttggta atctctaatg ccatgtcctg agtaatttca tcaacaccaa
    60001 agagttgcgg gtcgatactt tctggattgg tcatggtgat gtagacattt tttcgatact
    60061 cactggcaat aaaatccatc tggaaatcat cctgatattt tagtaacctt agtaggtagc
    60121 ctttgtccaa agtgacatta tgttcatagg cccatttttg ttcaggcatg tgggtcaagg
    60181 ccccattaaa agtgatgatt ggggtcttta aattgagctg cagatagtag cccagtgcca
    60241 tgcggtaagg acggcctgtt gaaataatga cgtggtggcc cttgtcttgg acagctttga
    60301 tggttttttg agtataggta gagatggtgt tgtcatgatg taataaggtt ccatccaaat
    60361 caatggcaat caatttttta gtcataatta aattatagca aattttgctc caagataaag
    60421 agaaaagata agttaagcgt attcattagt aaaaaagata ggataactgt ttttttaatg
    60481 aataaatgaa gttatagacg ttgaaaagtg aacaaaaaaa tggtaacata ttgttattgt
    60541 tcattttaat acgaacaata acaataataa tgaggtgtca aaaagactta tctagtgata
    60601 agcgcttttt gattttacct actatttaat taaggagact ccatttcaat ggaaaagttt
    60661 tttaagttaa gcgaaaatgg gacaactgtc tcaactgaga ttatggctgg tttaacgacc
    60721 ttttttgcca tgtcctatat tttgtttgtt aacccaagta ttttaggtgc agcggggatg
    60781 ccctctaatg ctgtcttttt ggctacgatt atcgcagcag ccatatcaac cttaattatg
    60841 ggactatttg ccaatgtgcc ttatgcgttg gcaccaggaa tgggacttaa cgcttttttc
    60901 acttatacag ttgtttttgc tttagggttt tcatggcaag aagccttggc aatggttttc
    60961 atttgtggat tattcaatat ttttattacc gtaaccaagt ttcgtaaaag tatcatcaag
    61021 gcgattccag ttagtttaca gcatgctatt ggtgggggaa ttggtgtctt tgtagcttat
    61081 ttaggattta aaaacgcaaa tatcattact ttttctatct ctgctgaaaa tatagtaatg
    61141 gtaaatggtg ttgaaccggc taaagcatcg gctaaaacat ttgcagatgg tctattattt
    61201 gtagacgcca atggtggagt tgtacctacg atttctagtt ttacggattc cggtgtatta
    61261 cttgctattt ttggtttact tttaacgaca gctcttgtga ttcgaaattt tagaggtgct
    61321 attttaattg gtattgtcgc aacaactctt gtaggtattc ctttaggaat agtggatgtg
    61381 tccaacctca attttgggat cagccatatt ggtgaagctt ggactgaatt aggtacaact
    61441 ttccttgcag ctttcgatgg tttgagttct ctttttagcg attcaagtcg tttaccgcta
    61501 gttttcatga ctatttttgc ttttagtcta tcagatactt ttgacacaat tggtaccttt
    61561 atcggaactg gtcgtcgaac aggtattttc tctcaagacg atgagaatgc tttggaaaat
    61621 agtataggct ttagttcaaa aatggaccgt gcgctttttg cagatgctat cggtacttct
    61681 attggggctt tggttggaac ttcaaatacg actacctatg ttgaatcagc agcaggaatt
    61741 gctgaaggtg gacgtactgg actaacagca gtctccaccg cagtatgctt cttattatca
    61801 atattgctat taccgcttgt aggtattgtc ccagctgctg ctacggctcc agctttaatt
    61861 attgtgggtg tcatgatggt gtcttctttt cttgatgtta attggagtaa atttgcagat
    61921 gctcttccag ctttttttgc agctttcttt atggcgctgt gttactctat ttcctatggt
    61981 attgccgctg cctttatttt ctattgtcta gtaaaagttg ttgagggaaa aacaaaagat
    62041 attcacccta ttatttgggg agcaaccttc ttgttcattg taaatttcat catattaact
    62101 atcttataac caaataattt acttattttg ctactaactg ccgcttcttt aattgatttt
    62161 aacctttaat ataaagaagc gtttttactt tacgaatacc ttattggagt catcttctag
    62221 gtagtgcttg gaagtatgtt ttttttctga tataatgttg ctatgtttta tagtgaaaat
    62281 gaatatactc ttaaagctta cggagaaacc ctaggtactt atttgtctat tggagatgtg
    62341 attgtattgt ctggcgactt aggtgccggt aaaacaacat tggcaaaagg tattgctaaa
    62401 gggatgggga ttagtcaaat gatcaaaagc ccaacttata ctattgttag agaatatgaa
    62461 ggacgtctac ctctttatca cttagatatt taccgtgttg gtgatgatcc agactctatt
    62521 gatttagatg attttctttt tggtaatggt gttaccgtta ttgagtgggg agaattatta
    62581 ggagagggat tattacaaga ctatttgcaa attaccatta ctaaacgaga caaaggtcgt
    62641 caactagact tgttagcgca tggtgagcgc tctcgtcagc ttctggagat aatgtcacat
    62701 ggttcagcaa agtctcgtta ttgaagaagg cgtacctcaa gatgcaaaag ctgtactttc
    62761 cttagtgacg gcagctgcca aagaaacaga ttttataaca ggcgtagaga ctatattaga
    62821 ggctactcct caagaattgt cagacttttt atcaagaagt caaacctctt ttattgattt
    62881 ttgcctgcta gctagattag atgaaaaagt agtagggctt ttaaatcttt ctggggaagt
    62941 attatcccaa ggccaagctg aagcagatgt atttatgtta gttgctaaga cttaccgtgg
    63001 ttatggtatc ggtcaattat tgttagagat tgctcttgat tgggctgaag aaaaccctta
    63061 tatcgaaagc cttaagttgg acgttcaagt aagaaatact aaggctattt acctgtataa
    63121 aaagtatggt tttcgtattg aaagtatgcg aaaaaacgac atcaaatcaa aaaatggaga
    63181 tgacttagat gtttatcata tgcgtaaatc tgtaagtcag taagtgaatc gatgaaaatt
    63241 ggaaaaaaaa tagttttaat gttcacagct attgtgttaa caactgtctt ggcattaggt
    63301 gtctatctaa ctagtgctta taccttctca acaggagaat tatcaaagac ctttaaagat
    63361 ttttcgacat cttcaaacaa aagtgatgcc attaaacaaa caagagcttt ttctatcttg
    63421 ttgatgggtg ttgatacagg ctcttcagag cgtgcctcca agtgggaagg aaacagtgat
    63481 tcgatgattt tggttacggt taatccaaag accaagaaaa caactatgac tagtttagaa
    63541 cgagatacct taaccacgtt atctggaccc aaaaataatg aaatgaatgg tgttgaagct
    63601 aagcttaacg ctgcttatgc agcaggtggc gctcagatgg ctattatgac cgtgcaagat
    63661 cttttgaata tcaccattga taactatgtt caaattaata tgcaaggcct tattgatctt
    63721 gtgaatgcag ttggagggat tacagttaca aatgagtttg attttcctat ctcgattgct
    63781 gaaaacgaac ctgaatatca agctactgtt gcgcctggaa cacacaaaat taacggtgaa
    63841 caagctttgg tttatgctcg tatgcgttat gatgatcctg agggagatta tggtcgacaa
    63901 aagcgtcaac gtgaagtcat tcaaaaggta ttgaaaaaaa tccttgctct tgatagcatt
    63961 agctcttatc ggaagatttt atctgctgta agtagtaata tgcaaacgaa tatcgaaatc
    64021 tcttctcgca ctatccctag tctattaggt tatcgtgacg cacttagaac tattaagact
    64081 tatcaactaa aaggagaaga tgccacttta tcagatggtg gatcatacca aattgttacc
    64141 tctaatcatt tgttagaaat ccaaaatcgt atccgaacag aattaggact tcataaggtt
    64201 aatcaattaa aaacaaatgc tactgtttat gaaaatttgt atgggtcaac taagtctcag
    64261 acagtaaaca acaactatga ctcttcaggc caggctccat cttattctga tagtcatagc
    64321 tcttacgcta attattcaag tggagtagat accggccaga gtgctagtac agaccaggac
    64381 tctactgctt caagccatag gccagctacg ccgtcttctt catcagatgc tttagcagct
    64441 gatgagtcta gctcatcagg gtctggatca ttagttcctc ctgctaatat caaccctcag
    64501 acctaacgtt ctgagggttt ttatgtttaa aatatccgat tttgaatata aaaaagacag
    64561 gtatcaaaga tgatagctgt ctgtgatttc aaataaagta tatgagggag ataatactat
    64621 ctggaatggt tgttagttaa aatgacggtt tggcaagtag gtgattcact agaaattagc
    64681 tcactatctt cttgatattt ggccatacga ttttggattt cagtgaggtg tgcttgtgtc
    64741 tcttggttaa agtagcgcca tttatgggcc aagtcctgac taatattttg aattactttt
    64801 ccttgactgt gaatgaggtc aaggtttgct ttaatgttat ctaaatcaag ttgggcagca
    64861 tcttttgctt gtctactgat ggataacagc tcttttatgg tacaacgttt ttgatatgct
    64921 ttgtaagcgg taaaagataa taatccgacg gctatcacgg ttttaacttt catgaactaa
    64981 cctcctgatt gatttgtcgg gcgagctttt ccaagacagg aaagtcaggc tcatgagtgg
    65041 tgtattgaat tgagataccg tcttcttcat tataacgagg aacgagatga acatgagcat
    65101 ggaaaacagt ttgtcccgct aaggcttcgt tattgttaat gatattcatg gcagtagcgc
    65161 cagtagctga ctggatagca cgagcaattt taggaatacg agcaaagaga tgactagctg
    65221 tctcagcagt catctctagt aagttacgaa catgttgctt aggaatgact agagtatgcc
    65281 cttttgtagt ttgtgagata tctaaaaagg cgaggacctg ctcatcttcg tagactttcg
    65341 aagaggggat atccccttga atgatgctgc aaaaaataca attttccatt ttatatcacc
    65401 ttctctactt gaatttgtta taatatatta taagtatatc aaaaactaga aagaaattat
    65461 atgttaaaca ttaaaaatct aacaggagga tatcacaata tccctgtttt aaacgatgtc
    65521 tcattttctg tagacaatgg agagttagtc ggtttgatcg ggctaaatgg tgctggaaag
    65581 tcaacaacta tcaacgaaat tattggcttt ttgaagcctt atcaaggaag tatttctatt
    65641 gatggtttaa ctctagcaga aaatgcagtt gcctaccgtc aaaaaatagg ttttatccca
    65701 gaaactccta gtctctatga agaattgacc ttatcagagc atatcaacac cgtagctatg
    65761 gcttatgata tcgacttaga agtggcacaa aaacgagcac aacctttctt ggaaatgttt
    65821 cgtttaactg acaaacttga atggtttcct gtcaattttt ctaaagggat gaaacaaaaa
    65881 gtcatgatta tttgtgcctt tgtcattgat ccaagtctat ttattcttga tgaaccattc
    65941 ttagggttag accctttagc tatttcagac ttaatccaaa cgctagaagt cgaaaaagca
    66001 aaaggaaaat ctattttgat gagtacacat gttttggact ctgctgaaag aatgtgtgat
    66061 cgttttgtga ttttgcatca tggacaagtt cgtgcccaag gaactcttgc tgacttgcaa
    66121 gaagcttttg gtgaccgttc agcgagctta aatgatatct atcttgcatt aacaaaagag
    66181 gattaagtat gaaagcatta tttctgaaac gccgtcaaga ctttcaaaaa caacaaaaca
    66241 aataccttcg ttacgtctta aatgatcact ttgttttggt gttgatgttt ttattaggct
    66301 ttgctatggt gcagtatggt cagctactaa accattttcc aacgaatcat ctacctattc
    66361 aggtttgcct tgggatattg atcccattat tgctcagtat gggatctata gcaacgtatc
    66421 tagaagaggc agatcagcat ttcttacttc caaaagaaga agaagtgatt tcttatatca
    66481 aacaagctga gcgactctct tttttgcttt ggggaacttt gcagactgct gtattgctct
    66541 ttttatatcc tatttttaga cgtttaggtc tgtctttatt tatttttatt atcttagttt
    66601 tgatattatt ggcactaaaa agagtagtgc ttagtcgaaa gacaagatat tttttgagag
    66661 gaaatcgttt agattgggca aaagctgtcg catttgaaag caatcgcaag caaagtattt
    66721 taaagtttta ttctcttttt acaacagtca aaggaatttc tacaaaagtg aaagaaagaa
    66781 cttatctaaa tcctctttta aaattagtta agcaaactcc ttcaaacctt tggctgtccc
    66841 tttatgctag agccttttta cgtagttcag attatttggg cttattttta cgactaatgc
    66901 tattaagctc attatctgta ttttttatcc ataatcttta tttgtcagta agtttagcac
    66961 tcatttttaa ctatttagtt gtattccaat tactttccct ttattatcac tacgattacc
    67021 attatatgac tagtctttat cctgaaaata gtcggagcaa gaagaaaaat atgttaagtt
    67081 ttttacgagg tttaagcttt ttaatgttaa tcgtcaatat gctgtgttgc tcatcagcgc
    67141 caaaagcact cattttgatt gtaggtatgg ttttcatagc ttgtatatat ctaccttata
    67201 agttaaagaa gatcattgac taagtagcct aaaacaagta aaataggggt aaacgactat
    67261 aaaagataga aaaggagggc gataaggtga caacgacgga acaagaactt accttgactc
    67321 ccttacgtgg gaaaagtggc aaagcttata aaggcactta tccaaatggg gaatgtgtct
    67381 ttataaaatt aaatacgacc cctattctac ctgccttagc aaaagaacag attgcgccac
    67441 agttactttg ggccaaacgc atgggcaatg gtgatatgat gagtgcccaa gaatggctta
    67501 acggccgtac attgaccaaa gaagatatga acagtaagca aatcattcat attctattgc
    67561 gccttcacaa atctaaaaaa ttagtcaatc aactgcttca gctcaattat aagattgaaa
    67621 acccatacga tttattggtt gattttgagc aaaatgcacc cttgcaaatt cagcaaaatt
    67681 catacttaca agctatcgtt aaagaattaa aacggagctt accagagttc aaatcagaag
    67741 tagcaacgat tgtgcatgga gatattaaac atagcaattg ggtgattact actagtggta
    67801 tgattttttt agtagattgg gattctgttc gtctaactga tcggatgtat gatgttgctt
    67861 acctgttgag ccactatatt ccacggtctc gttggtcaga atggctgtct tattatggct
    67921 ataaaaataa tgacaaggtt atgcaaaaaa ttatttggta tggtcaattt tctcacctga
    67981 cacaaattct caagtgtttt gacaagcgtg acatggagca tgtgaatcag gagatttatg
    68041 ccctcagaaa atttagagaa atatttagaa agaaataatg cgagttagaa aacgaaaagg
    68101 tgctgaggag cacttagcta ataacccaca ctatgtgata ttaaatccag aagatgccaa
    68161 gggccgttgg catgacgttt ttggaaatga ccgtcctatt catatcgaag ttggttcagg
    68221 aaagggcgga tttatcacag ggatggcctt gaaaaatcct gatattaact acattggcat
    68281 tgatattcaa ttatctgtcc taagctacgc cttggataag gtattagctt cagaagtacc
    68341 caatgtcaaa cttctgcgag tggatggatc aagtttaacc aactattttg aagatggtga
    68401 ggtggatatg atgtacctca acttttcaga tccttggcca aaaaccaagc atgaaaaacg
    68461 tcgtttgacc tacaaggatt tcttagacac ttacaagcgt atcttgccag aacacggtga
    68521 aattcatttt aaaaccgata atcggggctt gtttgagtac agtttagcta gtttttctca
    68581 atacggcatg accttgagac agatctggct tgacttacac gctagtaact atgaaggaaa
    68641 tgtcatgaca gaatatgaag agaagttctc taataaaggt caagtcattt accgagttga
    68701 ggcaaatttc tagtagtatt ttgtttcaaa atatgataac ataaaggagt tgatacagta
    68761 ttaacttctt tagtaatgga gaggtcgcat agtggcttag tgcgcacgct tggaaagcgt
    68821 gtagtcctta acgaggctcg ggggttcgaa tcccctcctc tccttttatc ctcttgatat
    68881 atcaagggtt tcggggtctt cgcccgtctt tcacccgtca aatttgagat tttgaaaaat
    68941 gtttttgacc tgatggtcat ttttttcttt taaactttct atctgatgag cgtaaacttt
    69001 gagtgtgatg ttgagatttt cgtgccccaa cagcttggat actgatatta aatcaacgcc
    69061 ctgcgctatc aaataagaag cgtaagtatg ccttagcgag tgattggtta gatttctgcc
    69121 agtcactctt tttataactt tgttcgttgc attatttgac gctccaaagc atacacgacc
    69181 gagtttatta tcctgataat agtcgctctt aaaatttctt agtatctcaa ggctattttt
    69241 atcaatcggt accttcctga tggactgctc gtttttggtc ggaccgaaat tttgagaaat
    69301 tgaataatca aaagttttat taatatcgat atagccattc tcaaaatcaa tgtctttcca
    69361 agtcaaccct tgaacctctg caaatcgtaa accggtgacg gctatgatat acgttgtcag
    69421 gtatgatggg tacttgactt tgcttttggc aaccttgata aaggcgaggt attctgattc
    69481 ttccatgaat ttctctgact cttctttagc gggtttttgc gatctaacaa tggccccatc
    69541 ggcaaaatta tccctaataa tgccatcacg aatggccatt ttacaagcac ccttgatttg
    69601 ataatgaaat ttatccagag tttgttgggc tacttttgcg ccaaagtcat taaggacttg
    69661 ctgataaaag gtgtgtgtga tactcttgag cttccgagtc ccaaaataat gttcgatgtg
    69721 cttaaaattt ttggtgtatg tctgccatgt ctttgcggta atgtgaggcc ttttatatat
    69781 gtctgcccaa cgtctgttgt agtctaaaac agtaatatct aaaaggtctg cggtcagcgt
    69841 atttaaatca atttctgctt gctgagcagc gacttttgca agtgtttttg ttttaaatcc
    69901 acgttttgat ttttctcttt ttttaccttg actgtcacga taggtgatgc gatactccca
    69961 cccagaacct aattttcgat aaaatgccat tgttttcacc tcatttttct gttaaaatgg
    70021 gtacaagaaa acgacctttt taatggttgt ttcttatacg gttttgcctc acgctctcct
    70081 cgccaaattt gagcgtgggg ttttttttat ttaaagaaat tattaacact tacatactga
    70141 gcctgcgtaa gcttagtttt taaggtttta acttctccgg tttgtatatt tcttaaggct
    70201 accgttgctt ttccaggtat ttcttcagaa gtggttgtgg cagtagtgtt aatggttcct
    70261 tttttctttc tagccccacc agccattccg ccgataatgg ttccaacgcc tggtgccaaa
    70321 actttaccta ttgctgcccc tcctagaaca ctactagaac gccctttttg agtagttttc
    70381 ccttttgtta ctgttttttc aataattcgt gacccatcaa attgaaggct aacaaactca
    70441 taaagctcag gagtttcaga ataaaaaccg atataatatt ttccatctat ggtttttcgt
    70501 atagccgttt gtgctcctag ttctaaattt agggcagggg gtaggattat tttgctctct
    70561 tgtgaggctt tttttcttag ttcgttagct ttaattgcac cgtctttagc tttccctgca
    70621 gctgttatgg caaattcttt taacttagct atatccatgc ttgtctcctt aactaattaa
    70681 aaactctaat tcttctttga tcatcacttc gtcagcgatt gaggtcagtt catacttttc
    70741 catgaattgg atgtagttga aatcctccat attatcccaa taggatagct cttcttttaa
    70801 gagatggtgt atcatacatc tatctgcttg tagctctgct ttttctttgt ttagtttgta
    70861 ataactcgca gtatgttctc tatgtcctag ttcatgatag atgactttgt gtttatatat
    70921 accgtcaaga taggtgtcaa tcgcaatgac gttgtgtttt ttattaaaca ttccaggggt
    70981 gtttgtaccc ctaccgtcaa agtacactaa atcgattcct ttttcctgac agactgtttc
    71041 tggtgtcatc atagagcagt cctctctatt ttctattttt gatgcgcgtt tccaatatag
    71101 atgtgataag gtctatatcc tcgtcgttga gttcgtgacc gtcgaagaag aaagtctctt
    71161 ctgcatcttt ttttagatca attgcgaccg aagcgtgccc atcttgcgca atcttaggat
    71221 tatcagttcg acctaatagg taatcggttg atacgtgaaa gtagtcagcg attagttgta
    71281 gtctttctgc tgaaggcttt ttatttttaa ttgtatagat tgaatttcta ctcaatccca
    71341 atttttcctc aagcaatccc aaggaaatac ctcttgattt tgcaagttct ttaattcttt
    71401 cgaatgttga aaacattgat ttgtcagcct ttctatgaga tgacaaaaaa tatctataaa
    71461 aaagcatgta aactacttga ctgattacaa actttagtct agaatataat ttgtaaagcg
    71521 aatataaaag cgaaacaaaa aacgaaaatt aaaactaaaa aaatat
//
LOCUS       DAUGJR010000004        60080 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUGJR010000004 DAUGJR010000000
VERSION     DAUGJR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60080
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.004"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            164..1396
                     /locus_tag="VH800_000249"
     CDS             164..1396
                     /locus_tag="VH800_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8361347.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFAGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLYVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            1564..2745
                     /locus_tag="VH800_000250"
     CDS             1564..2745
                     /locus_tag="VH800_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8361348.1"
                     /translation="MTKRIILTIFTFICFSVMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRVNA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSSKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(2897..4315)
                     /gene="sufB"
                     /locus_tag="VH800_000251"
     CDS             complement(2897..4315)
                     /gene="sufB"
                     /locus_tag="VH800_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEQ8361349.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(4308..4787)
                     /locus_tag="VH800_000252"
     CDS             complement(4308..4787)
                     /locus_tag="VH800_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEQ8361350.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(4774..6000)
                     /locus_tag="VH800_000253"
     CDS             complement(4774..6000)
                     /locus_tag="VH800_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8361351.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATLKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(6031..7293)
                     /gene="sufD"
                     /locus_tag="VH800_000254"
     CDS             complement(6031..7293)
                     /gene="sufD"
                     /locus_tag="VH800_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEQ8361352.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKISANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKDAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(7388..8158)
                     /gene="sufC"
                     /locus_tag="VH800_000255"
     CDS             complement(7388..8158)
                     /gene="sufC"
                     /locus_tag="VH800_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEQ8361353.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(8280..9449)
                     /locus_tag="VH800_000256"
     CDS             complement(8280..9449)
                     /locus_tag="VH800_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEQ8361354.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(9456..10217)
                     /gene="mecA"
                     /locus_tag="VH800_000257"
     CDS             complement(9456..10217)
                     /gene="mecA"
                     /locus_tag="VH800_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEQ8361355.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(10363..11202)
                     /locus_tag="VH800_000258"
     CDS             complement(10363..11202)
                     /locus_tag="VH800_000258"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEQ8361356.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(11268..13166)
                     /locus_tag="VH800_000259"
     CDS             complement(11268..13166)
                     /locus_tag="VH800_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEQ8361357.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRTGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGKEPV
                     DVSTSKKNKIVALETKISRRRTLLQLLFGKVIPLVEVGFLLWQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLILNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGGGAF"
     gene            13364..14932
                     /locus_tag="VH800_000260"
     CDS             13364..14932
                     /locus_tag="VH800_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8361358.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            14925..15665
                     /locus_tag="VH800_000261"
     CDS             14925..15665
                     /locus_tag="VH800_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361359.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     ITEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            15807..15923
                     /locus_tag="VH800_000262"
     CDS             15807..15923
                     /locus_tag="VH800_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEQ8361360.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(16149..17159)
                     /gene="gap"
                     /locus_tag="VH800_000263"
     CDS             complement(16149..17159)
                     /gene="gap"
                     /locus_tag="VH800_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEQ8361361.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(17507..19585)
                     /gene="fusA"
                     /locus_tag="VH800_000264"
     CDS             complement(17507..19585)
                     /gene="fusA"
                     /locus_tag="VH800_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEQ8361362.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(19952..20422)
                     /gene="rpsG"
                     /locus_tag="VH800_000265"
     CDS             complement(19952..20422)
                     /gene="rpsG"
                     /locus_tag="VH800_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEQ8361363.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFNAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(20443..20856)
                     /gene="rpsL"
                     /locus_tag="VH800_000266"
     CDS             complement(20443..20856)
                     /gene="rpsL"
                     /locus_tag="VH800_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEQ8361364.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(21064..23685)
                     /locus_tag="VH800_000267"
     CDS             complement(21064..23685)
                     /locus_tag="VH800_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEQ8361365.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKHNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESK"
     gene            complement(23676..24515)
                     /gene="purR"
                     /locus_tag="VH800_000268"
     CDS             complement(23676..24515)
                     /gene="purR"
                     /locus_tag="VH800_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEQ8361366.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(24782..25720)
                     /locus_tag="VH800_000269"
     CDS             complement(24782..25720)
                     /locus_tag="VH800_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEQ8361367.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(25710..26981)
                     /locus_tag="VH800_000270"
     CDS             complement(25710..26981)
                     /locus_tag="VH800_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEQ8361368.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQAGLYQQLTDIRDVLHRSLSDSRDRSDKRLEKINQ
                     QVNQSLKNMQESNEKRLEKMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNASFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            complement(26983..27615)
                     /locus_tag="VH800_000271"
     CDS             complement(26983..27615)
                     /locus_tag="VH800_000271"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEQ8361369.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(27608..28270)
                     /locus_tag="VH800_000272"
     CDS             complement(27608..28270)
                     /locus_tag="VH800_000272"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEQ8361370.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(28280..29152)
                     /gene="rsgA"
                     /locus_tag="VH800_000273"
     CDS             complement(28280..29152)
                     /gene="rsgA"
                     /locus_tag="VH800_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEQ8361371.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALEIGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(29576..30448)
                     /gene="rsmA"
                     /locus_tag="VH800_000274"
     CDS             complement(29576..30448)
                     /gene="rsmA"
                     /locus_tag="VH800_000274"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEQ8361372.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(30562..31152)
                     /gene="rnmV"
                     /locus_tag="VH800_000275"
     CDS             complement(30562..31152)
                     /gene="rnmV"
                     /locus_tag="VH800_000275"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEQ8361373.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(31124..31915)
                     /locus_tag="VH800_000276"
     CDS             complement(31124..31915)
                     /locus_tag="VH800_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEQ8361374.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD"
     gene            32200..33030
                     /locus_tag="VH800_000277"
     CDS             32200..33030
                     /locus_tag="VH800_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEQ8361375.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDSSERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            complement(33141..34079)
                     /locus_tag="VH800_000278"
     CDS             complement(33141..34079)
                     /locus_tag="VH800_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8361376.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDEGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVVLAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(34101..35015)
                     /locus_tag="VH800_000279"
     CDS             complement(34101..35015)
                     /locus_tag="VH800_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEQ8361377.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGNISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIADKDLEKAKALQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(35027..35689)
                     /locus_tag="VH800_000280"
     CDS             complement(35027..35689)
                     /locus_tag="VH800_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEQ8361378.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKYYFKSGLRLGLIELGIMTICLLDLF
                     LIRNQSGLVFQGFKVLCVAVLFLVVILFLYAYPQAVKRDLSLSTLFKRSFLLAGLFFP
                     WSFAFLAFICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(35846..36676)
                     /locus_tag="VH800_000281"
     CDS             complement(35846..36676)
                     /locus_tag="VH800_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8361379.1"
                     /translation="MTKKKLTASDILTTVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(36689..37576)
                     /locus_tag="VH800_000282"
     CDS             complement(36689..37576)
                     /locus_tag="VH800_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8361380.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTEFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(37679..38998)
                     /locus_tag="VH800_000283"
     CDS             complement(37679..38998)
                     /locus_tag="VH800_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8361381.1"
                     /translation="MNMKKLASLAMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(39047..39751)
                     /locus_tag="VH800_000284"
     CDS             complement(39047..39751)
                     /locus_tag="VH800_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEQ8361382.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLMAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            complement(40025..40159)
                     /gene="rpmH"
                     /locus_tag="VH800_000285"
     CDS             complement(40025..40159)
                     /gene="rpmH"
                     /locus_tag="VH800_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEQ8361383.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(40474..41388)
                     /locus_tag="VH800_000286"
     CDS             complement(40474..41388)
                     /locus_tag="VH800_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEQ8361384.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINRQNTPAVNSADVEPEEIKATQRLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(41400..42227)
                     /locus_tag="VH800_000287"
     CDS             complement(41400..42227)
                     /locus_tag="VH800_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8361385.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQRKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(42193..42552)
                     /gene="rnpA"
                     /locus_tag="VH800_000288"
     CDS             complement(42193..42552)
                     /gene="rnpA"
                     /locus_tag="VH800_000288"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEQ8361386.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            complement(43092..43832)
                     /locus_tag="VH800_000289"
     CDS             complement(43092..43832)
                     /locus_tag="VH800_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8361387.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(43836..45119)
                     /locus_tag="VH800_000290"
     CDS             complement(43836..45119)
                     /locus_tag="VH800_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8361388.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSIIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            complement(45116..46462)
                     /locus_tag="VH800_000291"
     CDS             complement(45116..46462)
                     /locus_tag="VH800_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8361389.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLEIYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLGDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            complement(46857..48302)
                     /locus_tag="VH800_000292"
     CDS             complement(46857..48302)
                     /locus_tag="VH800_000292"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEQ8361390.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVIAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            complement(48484..49194)
                     /locus_tag="VH800_000293"
     CDS             complement(48484..49194)
                     /locus_tag="VH800_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEQ8361391.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            complement(49325..49822)
                     /locus_tag="VH800_000294"
     CDS             complement(49325..49822)
                     /locus_tag="VH800_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEQ8361392.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVREDMAKIRASSLISDDVVINGAVYDVDTGKM
                     TQVME"
     gene            complement(50011..51372)
                     /gene="radA"
                     /locus_tag="VH800_000295"
     CDS             complement(50011..51372)
                     /gene="radA"
                     /locus_tag="VH800_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEQ8361393.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNA
                     VFS"
     gene            complement(51453..51899)
                     /locus_tag="VH800_000296"
     CDS             complement(51453..51899)
                     /locus_tag="VH800_000296"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEQ8361394.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            complement(52009..52776)
                     /locus_tag="VH800_000297"
     CDS             complement(52009..52776)
                     /locus_tag="VH800_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEQ8361395.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            complement(52894..54678)
                     /locus_tag="VH800_000298"
     CDS             complement(52894..54678)
                     /locus_tag="VH800_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361396.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLIQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTMTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            complement(54681..56387)
                     /locus_tag="VH800_000299"
     CDS             complement(54681..56387)
                     /locus_tag="VH800_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361397.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            complement(56380..56829)
                     /locus_tag="VH800_000300"
     CDS             complement(56380..56829)
                     /locus_tag="VH800_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8361398.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            57127..58143
                     /locus_tag="VH800_000301"
     CDS             57127..58143
                     /locus_tag="VH800_000301"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8361399.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            58176..59075
                     /gene="galU"
                     /locus_tag="VH800_000302"
     CDS             58176..59075
                     /gene="galU"
                     /locus_tag="VH800_000302"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEQ8361400.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(59174..59845)
                     /locus_tag="VH800_000303"
     CDS             complement(59174..59845)
                     /locus_tag="VH800_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEQ8361401.1"
                     /translation="MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
BASE COUNT        18234 a        12815 c        10874 g        18157 t
ORIGIN      
        1 cgttacactc cttttttaat gaggtttcaa ttagtttaat aaagattgtc attctctcat
       61 ggtagcgttt tattacatca ctactcttgt gaggtaagtc attaccttag acaaaaatat
      121 ggtataatta aaaaaataat acttgagtaa ggataatcta taaatgatca aacgattaat
      181 ttccctagtg gtcatcgcct tattttttgc agcaagcact gttagcggtg aagagtattc
      241 ggtaactgct aagcatgcga ttgccgttga ccttgaaagt ggcaaagttt tatacgaaaa
      301 agatgctaaa gaagttgtcc cagtcgcctc agtcagtaag ctcttgacaa cctatctggt
      361 ttacaaagaa gtttctaagg gcaagctaaa ttgggatagt cctgtaacta tttctaacta
      421 cccttatgaa ctcactacaa actatactat tagtaacgtt cctcttgata agagaaaata
      481 taccgttaaa gaacttttaa gtgcgttagt tgttaataac gccaatagcc ccgctattgc
      541 tttagctgaa aaaataggcg gaaccgaacc caaatttgtt gacaaaatga aaaaacaatt
      601 aagacaatgg ggcatttccg atgcaaaggt cgtcaattca actggcttaa ctaaccattt
      661 tttaggagct aatacttatc ctaatacaga accagatgat gaaaattgtt tttgcgccac
      721 tgatttagct attattgcca ggcatctctt attagaattt ccagaagtac tgaaattatc
      781 tagcaaatcc tccactattt ttgctggaca aaccatttac agttataatt acatgcttaa
      841 aggcatgcct tgttatcgag aaggcgtgga tggtcttttt gttggttatt ctaaaaaagc
      901 cggtgcttct tttgtagcta ctagtgtcga aaatcaaatg agggttatta cagtagtttt
      961 aaatgctgat caaagccacg aggatgattt agctatattt aaaacaacca atcaattgtt
     1021 gcagtacctt ttaattaatt ttcaaaaagt ccagttaatt gaaaataata aaccagtaaa
     1081 aacgttatat gtcttagaca gtcctgaaaa aactgtcaaa cttgtagccc aaaatagttt
     1141 attttttatc aaaccaatac atacaaagac caaaaatacc gtccatatta ctaagaaatc
     1201 atccacaatg atcgcacctc tatcaaaggg acaagtctta ggtagagcaa cccttcaaga
     1261 taaacatctt attggacaag gttatctgga tactcctcct tctatcaatc ttatccttca
     1321 aaaaaacatt tctaaaagtt tctttttaaa ggtctggtgg aaccgttttg tgaggtatgt
     1381 caatacctct ttatagaata acacaatgct ttttgtatga cattgactga cagagtactt
     1441 ctgcagtctt tttcattttt atttaagcaa actaggccaa tcctaacaat ttttcaaaaa
     1501 aacttcacat tgtattagca aagtgatata ctgaaaatgc attacattta aaggagtcgg
     1561 aaattgacca aaagaattat actaactatt tttaccttta tttgcttttc ggtgatgcct
     1621 cttgtccacg ccgaagatgt catggatatt acaaggcaag caggctacac agttagtgag
     1681 gttaatcgac caaaatcttc tattgtcgtt gatgcaaata gttcagatat tctttggcaa
     1741 gataatattg atattcctag ggatcctgct agtatgtcta agatgtttac gctttacatt
     1801 ttatttgaag agctcgctaa gggaaaaatt acgatggaca ctactattac ggcaactcca
     1861 accgatcaag ctatcgctaa catttatgag attagcaata ataatatcgt cgctggagta
     1921 gcttatccta ttcgtgatct tattactatg acagctgtgc cttcatcaaa tgcagcaact
     1981 gttatgattg ccaattattt atcaaacaat gatgcttctg cgtttatcga tcgtgttaat
     2041 gccacagcca aacaattagg catgactaac actcattttt caaacgctag tggtgcagca
     2101 gcacaagctt ttcaaggtta ttataatcct actaaatatg atttatctgc ttcaaatatt
     2161 acgaccgctc gagatttgtc caagttactc tatgccttct taaaaaaata ccctgaaatt
     2221 atctccttta caaataaatc tgttgtgcac actatggtag gaacgccata tgaagaagaa
     2281 tttcacacct ataaccactc tctcccagat aatcaatttg gtatgaaagg agttgatgga
     2341 ttaaaaacag gttctagtcc cagtgctgct tttaacgcca tgataactgc caaaagaggc
     2401 aaaactcgac tcattactat tgtcatgggg gtcggagatt ggtcagatca aaacggggag
     2461 ttttatagac atcctttcgt caatgccttg actgagaaag ggtttaaaga tagtaagacc
     2521 ttatccaaaa aagcacgcca aaaactcgaa aaattagtgc cacaaaccaa aaaagaaaca
     2581 tcatctaaac agcagcactt caaagccact aaaaagcaat cgtacttgga aagagtcgaa
     2641 gattttatga atcacaacca cactttcttg cttatttgct tagctatctt tataattact
     2701 atccttttac taagcctcgt tgtctttgca atgggacgcc aataatgaat tatcaaaaac
     2761 ctctgtcaaa gcacagaggt ttttgatatg ttatcttacg tgttcaaggc aactaaaaac
     2821 taaccacttg gggttagtac tacaactcat aaaatcctat ctcaaagatc tttcagatgg
     2881 ataagagaaa atgcaattaa ccgacagaac cttccatctc ataggaaatc aatcgattga
     2941 gttcgaccgc gtattccatt ggcaattctt tggtaaaagg ctccacaaat cccatgacaa
     3001 tcatctctgt ggcttcgctt tctgataagc cacggctcat gagatagtag agttgttctt
     3061 cagaaatctt agacactttg gcttcatgtt ctaacgccac ctgtgaatta tgaatttcgt
     3121 taaatgggat tgtatctgat ttagaaatat cgtccatcaa aatagtatca cattcaatat
     3181 gggaaacgga ttttttagat tgcttgttaa aggtcacttg gccacgataa tctactttac
     3241 caccagactt ggcaattgat tttgacacaa ttgatgatga tgtatgtgga gcattgtgaa
     3301 tcattttagc ccctgtatct tggtgttgac ctgcattagc aaaggcaata gacagcatgg
     3361 tgccacgcgc acctggccca tcaagataaa cagaagggta cttcatggtg gttttagctc
     3421 ctagattgcc atcaatccat tccactgttg catccgtaag ggcgcgtgca cgttttgtta
     3481 ctagattata cacattgtct gaccagtttt gaatggtggt ataacgcatg tatgcaccat
     3541 caagcgcaaa gatttcaacg atagcagcat gtaagctgtt acttgaataa gtgggagctg
     3601 tacatccttc aacataatga acacttgctc cttcatcaac aataatcaat gtccgctcaa
     3661 attgaccagt attttcattg ttaatgcgga aataagtttg caaagggata tctaccttga
     3721 cccctttagg aacataaata aaggtaccac cagaccaagc tgctgaatta agggctgcta
     3781 atttgttgtc tgttggcgga accagtttgg caaagtattg tttgaacaaa tcaggatatt
     3841 ctttgagggc ggaatcggta tctgtaaaga taatccctag cttttcaaat tcacccttca
     3901 tgttatggta aaccacttct gactcatact gagctgatgc cccagcaaga taagcacgtt
     3961 ctgcttctgg aattccaata cgatcaaagg tttcttttat tttttctgga acatcatccc
     4021 aagaacgagc tggcttatca gatgcttttt gatagtaaat gatatcatca aagttaatat
     4081 ctgataagtc tgctccccag gtttgcatcg gcattttatt aaaggtttcc aaggatttta
     4141 aacgaaactc caacatccac tcaggttcat ttttggcagc tgatagttcg cgaaccactg
     4201 cctcactcaa tccttttcct gtagaataaa tgggctctac atcatcgtga aatccaaatt
     4261 ggtagtcccc taagtcaatt ggctttggct ctactttctc atttatatca gacatttttc
     4321 ccttccttta cattttggtc cgtgaggtgc tgagcattgg cacttcgttt aatggcttcc
     4381 ttgagagcat tccaagctag ggtagagcat ttgatacgct gtggaaattt tgcaactcct
     4441 gccaacaatt ctgcttcacc tagctctttt tgagcaggat tttcctgtcc ttgtaccatc
     4501 tctgaaaaaa tatcagctaa cgcgagtgct tcttctttac ttttaccaat aacagcatct
     4561 gtcatcatgc ttgatgaagc tgtggaaatg gtacagccgt tgcctgcaaa agcaatatct
     4621 tcaattttat cttcgtcaaa cttaacggtc aaagaaatca catcaccaca agtcggatta
     4681 ttcagttgaa cagcctctac gccatctagt tgcccatgat gatgtggacg tttcgaatgg
     4741 tccgctacca cagccatgta tagatggttc agtttagaga gtgccattga aaaactcctt
     4801 tgcttttaga attgcttcga ctagacggtc acaatctgcc ttggtgttat agatataaaa
     4861 acttgctcta acagttgctg gtacacctaa ataactaaga agaggttggg cgcagtggtg
     4921 ccctgctctt actgcaacac cttcatagtc caaggctgtt gccaagtcat gaggatgcaa
     4981 atcatccaga ttaaaagaaa tcagaccaga tcttgcacta ggctggcttg gtccatatat
     5041 ggtaagcccc tcaatagctt ctaatttcgg caagacatag gctattagtt ctgcttcatg
     5101 cgcatgtata tcagccatgc ctagtctctg aaggtaagaa atggctgcgc ttagcccaat
     5161 agcaccagct atgtgaggtg ttcctgcttc aaacttccag ggcaattctt tccaagtggc
     5221 ctcttgttcg taaacaaaat caatcatttc tccgccaaat tcaagaggct ccacttgatt
     5281 caaaagctct tctttgccgt aaagaacacc caaacctgtt ggccccaaca tcttatgagc
     5341 tgaaaaagca aagaaatcac aatccaagtc ttgaacatca atagccaaat gtggaaccga
     5401 ctgggcaccg tcaacaacaa ggtaggctcc tttagcatgt gccagcttgg caatttcttt
     5461 aatgggattg atgcaaccaa gaacattgga gacatgtact aggctaacaa aacgtgtttt
     5521 tgtcgtcaat ttgtttgcca aatcgtccat gtcaagttgg ccatctttta aataaacata
     5581 gactaacctt gctcctgttt tttgacaggc ttgttgccaa ggaatgatat tggcatgatg
     5641 ctccataatc gaaatcaaca cctcatcttc tggcgtcaag acctgctctg caaaccgagc
     5701 aacccaattc aaactggttg ttgttcctct ggtaaagagc acttccttac ttgatttagc
     5761 atgaataaag tcagcaacct gctggcgact ggcctcatat ttgagcgttg cacgttcagc
     5821 caaggtatga actcctcggt ggacattagc attatcttct tgataatagg attgcaaagc
     5881 ctcaagaaca agcgccggtt tttgtgtggt ggcggcatta tccaaataaa caaggggttc
     5941 atcattgact tgttgattta agatttgaaa gtcttgttta atgtcttttg cgtctagcaa
     6001 tactaacctc tttctttttg gcagtaggtc ttaacgatta agcaatttct catctaaaac
     6061 cttaataatc tcttggcgga ctgatggaat aggaatttca gcgataaccg ctcctaggaa
     6121 tcctctaata accaatcgtt ctgctgtttc ttgatccagt cctcgactca tcaagtaata
     6181 catatcttca gggtcaacct gaccgataga agctgcatga cctgctgtta cttcattttc
     6241 atcaattaag aggattggat tggcatcggc tcttgcttgg tcagaaagca tcaaaacacg
     6301 gctttcttgt tgagcatcag ctcccttagc gtcttttaga atatgaccaa tcccgttaaa
     6361 cgttaaggtg ccacgttcca aaatcacacc atgctgtaaa atatgaccga ccgtacgttg
     6421 accatagttg gtcacgcgcg tgtcaatacc ttgtacctga cgaccacttg aggctgcaac
     6481 aactttcaaa tcagcttgtg agccctgacc aatcaaatca ctgtcaaaat cagcaatgac
     6541 attgccttca ttcatcacag ctaaggccca atcaatgttg gcatccttct ctaaacgtcc
     6601 tcgacggcta atataggttg tcactgaagg acctaagcgg tcgatagccg agaatttaat
     6661 ctggctgcct gcttgagcaa tcacttctac actgatatta gcgctgatct tttgagtggc
     6721 attgccaata gattcaaaac gctctaaata ggtgaactta ctttcttttc ctgcaatcac
     6781 tagaacatgc ttgttaaaag gaacgtcact gtcactatct tgtaagaaaa tagcttcaat
     6841 aggagttgtg atttccaagt gatcaggaac gtagagcacg gctgcgctat taaaataagc
     6901 agtgtggtag gcagctagtt tgtcttcatc aaaagctaat gcctgaccaa aatgagcttc
     6961 aattacttct gggatttcct caagcgccgt ataaaaatca ctgaaaacaa ctcccttgtc
     7021 aattaacgcc attggtaact gttctaagac tgtttgcgtg cctacctgaa caagctttgg
     7081 gttatctcca atagctataa aatctggaac actagctaga ctttcatttt ctgttaaggt
     7141 accatctcct agattccaac ggtgaaattt aaccctttcg atggttggta attccaaatt
     7201 tggaatggct tctaatgccg ctaaacgccg ttcttgcagc caagcaggct cagcgtgggc
     7261 ttgcgaaaaa gccactagtt tttcttttgt catctgtcaa tcctttgtct ctggttttta
     7321 aattggctgg gtatatagaa catcacctag ctttttgtag aaagctaaag taattgtctc
     7381 caaaaactta actttcttcc ttatactcga ttcccagatc ctgtgcaata cctgcgtagc
     7441 cttctttttc aagacgagta gccaaggcag catcaccaga taagacaata cgaccatcca
     7501 tcataacatg aactaggtct ggggtaatgt aattcaacaa acgttgatag tgggtgataa
     7561 tcatagctcc aaagtctttc ccacgcatct cattaacccc tttagagact acttttaggg
     7621 catcaatatc aagaccagaa tcaatctcat ctaacaaagc aaatttaggc tctaacatga
     7681 gcaattgaag aatttcattg cgttttttct ccccaccaga aaaaccttca ttgaggtaac
     7741 gctctgccat ctcttctttc atacctaaca aagccatttt ctcatcaagt ttggtgataa
     7801 aatctcgcac ggaaatctta tcctcatctg ccttaccggc attcattgct gcacgcataa
     7861 attcagcgtt ggtaatccct ggaatttctg aagggtattg catggcgaga aaaagtccca
     7921 gtctcgcacg ctcatcaact tctagatcga gaatattgac cccgtcaagc aaaatttgcc
     7981 cttgggtcac ttcgtagtta ggatttccca taatagctgc tgaaagggta gactttcctg
     8041 tcccatttgg ccccataatg gcagctactt ccccagtttt aagagttagg ttaacccctt
     8101 tcaaaatctc tttaccttct attgaaacat gtaaattatt aatctcaaga attgacatga
     8161 tacacccctt attttctctg tcatctatac catctcaaga aaagacagtg tcatttgcac
     8221 tgcttttttt ataatggtca ctgcatctat tatagcaaaa aaagccttac tcggcttttt
     8281 tagtgtttca aatccttctt ttctttccat ttcagaagca ttgcttgacg ataatcacta
     8341 ttaccaataa actttaacaa gttaaacaaa ggcgttcgct tttcacccca gatctccaat
     8401 ccttcaataa aaacttctaa accaaataaa agtccaagca tcaagaggac gccaccaatt
     8461 cgactagaaa catttaaaag taaagaaata agggaaaaaa gcatggtaat accataaact
     8521 actaagacag ctcctcgatg agtaaagccc attgataaga gtcgatgatg caggtgcatc
     8581 ttatccggct cgtagaattt ttgacctgat aaactacgtc gaataatagc cacgatggta
     8641 tccataatgg gtacaccaag aataataaca ggtgtcacca cagccacagc cgttgaattt
     8701 ttcaatcctt gaagagacaa aacccctatc ataaagccaa taaagagggc tcctgtgtca
     8761 cccaaataaa tcatagctgg atggtaatta taaggaaaaa atcctgcaat agcagaaatc
     8821 aagaccaaaa tggttaacgt caaaaagaaa tccttttgag gtaaaaagaa ataagataca
     8881 atagccatgg tcactaaact aataatagag accccactaa ccaaaccatc caaaccgtca
     8941 atcaagttaa tagcattagt gatggaaaca atccacagga ctgttaagaa taaggttaag
     9001 aaaggaccaa aaactaacaa cggccctcca aaaggaattt tgaagctatc aaatttaaag
     9061 tcggtaaaag cccagacaat cactgcacca attagaatac caaacatctt taatttagga
     9121 cttaactcat acaaatcatc taaaaaacca gtaagggtaa ttactgtagc accaatcacg
     9181 acaggtaaaa tataactgaa gtaggtctga ccaaaaaaca tggcgccttt agaagcaatc
     9241 ggaataagtc ccaaacttgc tactaaaaaa gacataaaaa tagctaatcc accactggtt
     9301 ggcatcggaa ccttattgac ccgtctggca ttgggattgt ctactgcacc cacacgaaag
     9361 gctaaaaagc gaacaagagg ggttaagaat aaggacatta acaaagcccc tatcagaaca
     9421 aggacataat ctattgtgaa tgaaaacata ctattttatc ccaactcaat cttttgtaat
     9481 tgctcaacag caccatcaag catcaattgt aagccatgct cttgtaaata agctcttgtt
     9541 tttgatccag ggtttgcatg ctcaatcaat ctcgcataca tgacgttcgc aaaataagat
     9601 ggttgttgct gaacatctaa taaaatagtc atatggtagc agttgctccc cttatataac
     9661 tctgaagctt ctatcgaaaa atcaatcgtt ttagcaaaag ccactgcctc tgtaatcgtt
     9721 gaaaaatcca atacataatg gacatagtct aaaggttctg actcatgatt agttgatgga
     9781 tcagccgcct cagactgatt agctagagtg gcttcaacaa catcttccat tatctcttca
     9841 attttttcca atttttcatg agctttgaca tctccctttt cacgcatgga ttgctccaag
     9901 ctcttgaaaa aatcttccgg agtcatttgg gacatatcac caaactctgc taaatcttca
     9961 agattaatat ctttatttat ctcagatttg gtaacaaaaa catctagacg gtccttgcgt
    10021 ggagtcactc gaaaactaag cataccacta tctttaaaat tatctggaag atcgagttcg
    10081 tccatcacag aatagaaaaa ctcttctgtt ttttcttgag gaatcaagaa atctttcaac
    10141 tccattcctc tttcttctaa atcgtccata ctaattgtta tttttagcgt tgtctcgcta
    10201 atttgtttca tttccattct caatacctcg cacgcgtagt cattttatta tactagaaat
    10261 gctgtaattt cgcaatttat gactaactcc tcgtctacaa aaggaaattt aaaaagcgac
    10321 agtccccaag gtctgtcgca acatcctaaa cgatatgtaa gtttaaaaaa caaatttaaa
    10381 gaagctataa ataagtaaaa ggcttcctaa cacaatacgg tatttcccaa aaatggtgaa
    10441 atcgtgtttc ttaacataat ctgtcaagaa cctaatcgcc aataaactaa ccacaaaagc
    10501 ggtcaagcta gccactaaaa gaataaggac ttgtgcaaaa tcaaggtgat ggccatcaag
    10561 gaaaaatttt acagccttta atccactata tccaaacatg gtaggaatgg ccaaaaagaa
    10621 ggtgaaatca gcggccactg ttcgactagt tcctaaaata atagctccta agatggtagc
    10681 ccctgatcga ctagtaccag gcacaatact taagacttga aaacaaccaa tgaagaaagc
    10741 tgttttgtaa gacattctag ctaattcagt gacagcaggt tcttgttgag catttcgttt
    10801 ttcaatccag ataaaggcaa tcccgtagac gattaaagcg atggcaatcg gaaccataaa
    10861 ataaaaatgt gcttcaaacc aattatcaag aggaaccgct attaaaatag aaggaataca
    10921 cgcaatcacc acttttagcc ataattgcca ggtaagctgt acttctcttg ctgttttccc
    10981 aggttgaaag ggattgagac gttcaaaata aatcaacata acagcgataa tcgcccctaa
    11041 ttgaataacg atattaaaca tttctataaa agccttatcc tgatttagtc ggataaattc
    11101 ctgcaccaaa atgaggtgac cagtgcttga aactggtaac cattctgtga ttccctcaat
    11161 gatgccaaag aaaatggctt ttagcaattc gataattaac atgttttctc cttattaacc
    11221 actcttattg tgattttcta aactgtgatt aatgccaagc agctttttta aaaggcaccg
    11281 ccgccgccac caccactaat cccgcctccg gaagagactg agaaatttga ggaagttgta
    11341 gctgaagaca agctagacac aaaggttggt gtcgtagcat acattaccat tgataattca
    11401 cctggtcgaa cagcttggta aacctcaggt aaggcaatac gatggacttt caaatagcgt
    11461 tccactttct tagcgtaacc aaataaggtg gcataaacca aaacacggtt ccaaacaacc
    11521 aaaccttcaa tagcaacatc ctcaaatttg tcaatgtctc gtatcatgtt tttaaagctc
    11581 tgccattgat gtaaccgaac acccccctca ggtgtttcaa tacccaattt cttgtattga
    11641 tctaacttca ggctaatgta aaagccaagg cacatcgtta gcaccattaa agcaaggtaa
    11701 atgagggcta acccactttc tttaatagcc aagtaaatca ataaaccact atttagaata
    11761 agcaacaaac aacctaatcc ctggacacta ttgctttttc gtttctctgc cggggtcatt
    11821 tgacgataag tatctggtaa gtttaacttt ttgatagttt ctaggacatt gtttgtaata
    11881 gctgccgacg cttttttcat cgccttaatc acctgctcag acgattgacg gacttcttgc
    11941 tcgagctttt tacctttgta cgttttcttt aattgtttaa tggtatcagc atcataatgg
    12001 tattgactaa acaattgatc caccggcaat gtcaccttgt ttccaaaagc catatctaag
    12061 aaggcagctt cctcatctgt cacacgatct aactgactga tttcaagata agctttccct
    12121 tcttctttcg ttaataaaag caccttttgg tcgatcagat ccaacaaggt agcttgaaca
    12181 agggcctcaa aggtcactcc tttagggatc aataatttct ggctttctga tgctgtaggg
    12241 gataaatagg caaaactctg tccataaatc gcttgtgtca acacaagagg cgaaagatct
    12301 tcagggactt cgtaactgtg atctgtatgg ttagccaaat gataacgatt gaattgtttc
    12361 tttaatcttg taaactgtat taactgccaa agaagaaaac ctacctctac cagaggaatg
    12421 actttgccaa atagcagctg taacaaggtc cttcgtctgg aaatcttagt ttctaacgct
    12481 acaattttat tctttttact cgttgaaaca tcaactggct cttttcccaa taatgctttt
    12541 ttatcccaat aagcatgcaa ttccagttgc cctgagacat tcttggcatt aatctgatag
    12601 cgactgttac cttcttttaa cacttgaggt ttcttttggt aatatcctct gtgagcccat
    12661 agattagaat cctgaatatc agttggggta gtgacggtca aactcacctt ttctaatgtt
    12721 ttgtcccaat cactaatcgg tgtccaattc agctctgcca cgtcttgata agctgttaaa
    12781 aggtggtgca gttgccagat aaccttgacg tcaaccttat caccagcttg gccagcatta
    12841 taaagtttta aacgatagcc atctccaagg tcactaaact cttgactaac aggtacctgt
    12901 tgaccattct gatatacctc aactttaggc ttttggtcaa tagcaaagcc cgctggcaaa
    12961 tgacctgtcc ggcccagcga aatatactgg ccgttataag aagtgtcaaa ttgataggtt
    13021 actttttgct caaaccgagc agtattttct tttgataaca gtaactgacc ttcatagttg
    13081 gtgatgctat agtctacatc agctgctttt attcgtatcc ctaaaagact gaagcagagc
    13141 acaagcgtca tcaaaatttt tttcatggca acatcctctt tctgccctca ttttaccata
    13201 ttttaaggag atgacaaaac ctaaaccaag tccttcatct tatttttaat cattattttg
    13261 aatatttttc catatttcaa cctattcact gataatatat tgaaatagga tgcaaattgc
    13321 tgtaaaatag gtctgaatac tatttttgaa acaggagacc tatatgaaaa agctaatcct
    13381 tagctgtttg gtcgccttgg cccttctgtt tggaggaatg agccgggctc aagcaaacca
    13441 atatttaaga gtcggaatgg aagcagccta tgctcctttt aactggactc aagatgacgc
    13501 ttcaaacggg gctgttccaa ttgaaggaac tagccaatac gccaacggtt acgatgtcca
    13561 agtcgctaaa aaagtcgcta aagctatgaa caaagaactt ttagtcgtta agacctcttg
    13621 gaccggttta attccagcat taacttctgg aaaaatcgat atgatcgctg ctggtatgag
    13681 tcctaccaaa gagcgtagaa acgaaattag cttctcaaac agctactaca ctagccaacc
    13741 tgttctagtc gtaactgcca atggcaaata tgctgatgca acaagcctca aggatttttc
    13801 tggagctaaa gtaactgccc agcaaggcgt ttggcatgtc aatctcttaa ctcaactaaa
    13861 aggtgctaag ttacaaacac caatgggaga tttctctcaa atgcgacaag cccttacttc
    13921 gggtgttatc gatgcctata tttctgaacg acctgaagcc atgactgctg aagctgctga
    13981 tagccgtttg aaaatgatca ctcttaaaaa agggtttgct gttgctgaat cagatgctgc
    14041 tatcgctgtc ggaatgaaaa aaaatgacga tcgtatggca actgtcaacc aagtgcttga
    14101 aggattttct caaacagatc gtatggccct gatggatgat atggttacca aacaacccgt
    14161 ggaaaagaaa gccgaagatg ctaaagcatc atttctaggc caaatgtggg ctatttttaa
    14221 aggtaactgg aagcaattct tacgtggaac tggaatgacc cttctgattt ccatggtcgg
    14281 aaccattaca ggtctcttta ttggattatt aatcggtatt ttccgtacag ctcctaaagc
    14341 taagcataaa gtagctgcct tgggacaaaa actctttggt tggttactca ctatttatat
    14401 cgaaatcttc cgtgggacac ctatgattgt tcaatctatg gttatctact acggaacagc
    14461 gcaagccttt ggtatttcga tcgaccgtac cctagcggct atttttatcg tatctatcaa
    14521 tacgggtgcc tatatgagtg aaattgttcg cggtggtatt ttcgctgtcg acaaaggtca
    14581 attcgaagca gcaactgctc ttggctttac tcacggacaa accatgcgta aaatcgtgct
    14641 accacaagtt gttcgcaaca ttttaccagc aacaggtaat gagtttgtca tcaatatcaa
    14701 agatacttct gtcttgaatg ttatctctgt tgtggaactt tacttctcag gtaataccgt
    14761 agccacacaa acctaccaat atttccaaac ctttacgatt atcgccatta tctactttgt
    14821 tcttaccttc acggtgacac gtatccttcg ttatattgaa cgccgtttcg atgccgatac
    14881 ttacaccact ggagcaaacc aaatgcagat tgcggaggtc tcaaatgtct aactcaatta
    14941 ttgaaatcaa aaatctcaaa aaatcttacg gcagcaatga agtactcaaa gatatctccc
    15001 tttctgttaa caagggagaa gtgatttcca ttatcggttc ttctggttct ggaaaatcaa
    15061 ccctcctgcg ctcgatcaat cttttggaag agccaagtgc cggtcaaatc ctctttcatg
    15121 gtgaagatgt ccttgctgaa cactacaact tgactcacta ccgtgaaaaa ctaggcatgg
    15181 ttttccaatc ctttaacttg tttgaaaacc taaatgtatt ggaaaatgct atcgtcgctc
    15241 aaaccaccgt cctcaaaaga gaccgtgcac aagccgaaca aatcgctaaa gaaaacctca
    15301 atgcggttgg tatgacagaa caatactggc aagccaaacc aaaacaatta tcaggggggc
    15361 aaaaacaacg ggttgccatt gccagagcct tatctgtcaa tccagaagcc atgctctttg
    15421 atgaaccaac atcagctctt gatcctgaaa tggttggtga ggtccttaaa accatgcaag
    15481 acttggcaaa atcagggttg accatgatta ttgttaccca tgaaatggaa tttgctcgtg
    15541 atgtttctga ccgtatcatc ttcatggata agggattgat tactgaagaa ggaagtcctc
    15601 aacaaatttt cgagaatcct acacaagatc gtaccaaaga atttttacaa cgcttcttaa
    15661 aataagataa aggatccaac tatttctatg ccagttgggt cttttttcaa ttcaaaaaga
    15721 atttgtcata aaatacttta ccagttaact attttatgct atacttattt ttgttaacgt
    15781 taataattta tatttaggag gataatatgg cagaaaaaac tgacttatcg tcagcttaca
    15841 gaagactgaa aagtcccaat attaaaacca gaaaacgtgc tctgaagatt attcacgagt
    15901 acaaacgtta cggtaaaaaa taagatttta ctttttatct ctccaaattt aagtcagaca
    15961 aaaaaaggct aagacacccc ttccatctta gcctttttgt atacagttta ttaagggaac
    16021 tattttaaaa tatcttttat gctagagtct agaatagttc aaaacgttaa aatcatacat
    16081 ttaaggtagt gtttaaagta tacgaaaaag aactcagcat aaaccaagct ctctttcgtt
    16141 ataactaatt atttagcaat ttttgcgaag tactcaagag tacgtacaag ttgagcagtg
    16201 taagacattt cgttgtcata ccatgataca actttaacca attgtgatcc gtcaacttcc
    16261 attactttag tttgagttgc gtcaaacaat gaaccgtatg atacgcctac gatatctgaa
    16321 gaaacgattg gatcttcagt gtaaccgaag ctatcgtttg aagcagcttt catagcagcg
    16381 ttgatttcgt caacagaaac gtttttgtca agagttacaa ccaactcagt tactgatcca
    16441 gttggaacag gaacacgttg tgcagcaccg tcaagtttac cgttaagttc tgggataaca
    16501 agaccgatag ctttagcagc accagttgag ttaggaacga tatttgcagc accagcgcgt
    16561 gcacgacgaa ggtcaccacc acggtgtggt ccgtcaagga tcatttggtc accagtgtaa
    16621 gcgtggattg tagtcataag acctttttga ataccgaatg catcgtgaag agctttagcc
    16681 ataggagcta aacagtttgt agtacatgaa gcacctgaga taactgtttc agtaccgtca
    16741 agaatgtcgt ggttagtgtt gaaaacaact gttttaacat cgtttccacc aggagctgtg
    16801 ataacaactt ttttagcacc gttagcatgt aagtgttttt cagctgcttc ttttttagca
    16861 aagaaaccag ttgcttcaag aacgatttca accccatcag ttgcccagtc gatgttttct
    16921 ggatcacgtt cagcagaaac tttgatgaag tttccgttta cttcaaatcc accttcttta
    16981 acttcaactg ttccatcaaa acgaccttga gttgtatcgt atttcaacaa gtgtgcaagc
    17041 atatttggat ctgtaaggtc attgatacga gttacttcaa caccttcgat gttttgaata
    17101 cggcggaatg caagacgtcc gatacgaccg aaaccgttaa taccaacttt aactaccatt
    17161 agtgatttcc tccttatgaa aatcaaaaga atattattta gagggaatgc tccctaccta
    17221 ttgtgaaaag attaacttac agtcatctgt aacaaccttt caacagaact attatataac
    17281 tatttcagaa aaaatgcaaa taaattagcc attttcataa agggcagctt ctttcttcta
    17341 gccttcaaaa cccaccaaat ataggaaagg gctttctttt ttctatgttc tattctgtaa
    17401 tttatctttt tattgggaaa gatttccaaa acttcaaact gtactataac gttctgttac
    17461 actaaaaaag aggttaggat agttatcctc aacctcttag tggtggttat tcacctttgt
    17521 ttttcttaat gatttcttct tgaactgact taggaacatc ttcatagtgg tcaaatacca
    17581 tcatgaatgt accacgtcct tgagtagcag aacgaagaac tgttgcataa ccgaacattt
    17641 cagcaagtgg aacataagca cgaacgattt ggctgttacc atgtgcttcc ataccatcaa
    17701 cgcgtccacg acgagctgtc acgtgtccca taacgtctcc aagattgtct tctggagctg
    17761 taatcgttac aagcatcatc ggctcaagga tagctggttg tgctgattta gctgcttctt
    17821 taagagcaag agatgctgcg atcttgaagg cagtttcaga tgagtcgaca tcgtggtatg
    17881 aaccatcgta aagtttagct ttaacgtcaa ccattgggta accagcaaga acaccgtttg
    17941 ccatagattc gatcaaccct ttttcaacag ctgggataaa ttcacgagga accacaccac
    18001 caacgatagc attttcgaat tcgaaacctt taccttcttc atttggtgta aattcaatcc
    18061 aaacatcacc gaattgacct ttaccaccag attggcgttt gaagaatcca cgagcttgtg
    18121 tagaagcacg gaatgtttca cggtaagata cttgaggagc accaacgtta gcttcaactt
    18181 tgaactcacg tttcatacgg tcaacaagga catcaaggtg aagttcaccc ataccagcga
    18241 taactgtttc accagtttca acgtttgttt caacacggaa tgttggatct tcttcagcaa
    18301 gtttttgaag ggcaacaccc atcttgtctt ggtctgcttt agattttggc tcaaccatca
    18361 actggataac tggttctgga acttcgattg actcaagaat aacttttgct ttttcatcag
    18421 tcaatgagtc accagttgtt gtgtctttca aaccaacagc ggcagcgatg tcaccagcgt
    18481 aaactgtttc aatttcttga cggctgtttg cgtgcatttg aaggatacgt ccgatacgct
    18541 cacgtttacc ttttgatgtg ttcataacgt aagaaccgct attaagaaca cctgagtaaa
    18601 cacggaagaa tgtcaaacga cctacgaatg ggtcagtcat gatcttgaag gcaagagctg
    18661 caaatggctc ttcatcagat gctggacgtt cttcttcagc atctgtatcc gggttaacac
    18721 ctttgattgc agggatgtca agtgggcttg gaaggtatgc gataaccgca tcaagcatca
    18781 attgaacacc tttgtttttg aaggcagaac cacaaagtac tgggaagaat tcaacgttga
    18841 ttgttgcttt acggatacca gcaatcaatt cgtcgttagt gatttcttca ccttcaaggt
    18901 atttcatcat caagtcttca tcagtttcag caactgcttc gattaatttt tcacggtatt
    18961 cttgagcttg ttctaagtat tcttctggaa tatcttcttc aagaatatct gtaccaaggt
    19021 cgttggtata gatttctgct ttcatcttga tcaagtcaat gataccacgg aaatcatctt
    19081 ctgcaccgat tggcaattgg attgggtgtg catttgcttg aagacggtca tgaagggttt
    19141 gtactgagta aaggaagtca gcaccgattt tatccatttt gttggcgaaa acgatacgtg
    19201 gaacaccgta ttcagttgct tgacgccaaa ctgtttcagt ttgaggctca acacccgatt
    19261 gtgagtcaag aacggttaca gcaccatcaa gaacacggag agaacgttgt acttcgatgg
    19321 tgaagtccac gtgtcctggt gtgtcgatga tgttaacgcg gtgaccatcc cattgagctg
    19381 ttgtagcggc agaagtaata gtgataccac gttcttgctc ttgctccatc cagtccattt
    19441 gtgatgcgcc ttcgtgcgtt tcaccgattt tatgaatttt accagtgtag taaaggatac
    19501 gctctgttgt agttgtttta ccagcatcga cgtgagccat gataccgata ttacgagttt
    19561 ttgcaagtga aaattcgcga gccatgtgtt tctcctattt ttttagttta ctctttcatt
    19621 atagcactat ttagcaaaaa cggataggca ggacctaccc gttatctaaa tatttgttgg
    19681 taaagataat acctattgcc tttataaggc ttggtatctt attcattgaa ctcaggctaa
    19741 acgctgtgtg aaaaagataa actttcctag agacaaaggt ttcttcgtca aatttcctat
    19801 tttcactttg cgttctatac gccttcgtat cttattaatt gagttcgagc tacaagccac
    19861 tgacaaaaag ataatagttc ctagaaactg aagtttctgc gtcaatttcc ctattttgtc
    19921 tagcatttgt ttgacgctaa aatatcttat attaccaacg gaagtgagca aaggcacggt
    19981 tagcttcagc cattttgtga gtgtcttcac gtttcttaac tgatgcacct gtgttgtttg
    20041 cagcatccat gatttcttta gcaagacgat ctttcatagt gtgttcacca cgagcacgtg
    20101 atgcgtttac caaccaacga agtccaagtg ttgtacgacg ttctggacga acttcaactg
    20161 ggacttggta gttagaacca ccgacacggc gtgcgcgtac ttcaagtaca ggcatgatgt
    20221 tgtccatagc tgtttcaaat acttcaagag cgtcatttcc tgttgcttct ttgatagcgt
    20281 tgaaagcatc gtaaacgata gtagcagctg taccacgttt accgtcaagc ataacacggt
    20341 tgataagacg tgttacgatt tttgagttat ataatggatc tggtaatact tcgcgtttag
    20401 gcgcttgatt tttacgactc attttctctt atcccccttc tattatcctt ttggacgttt
    20461 cgcaccgtat ttagaacggc cttgtttacg gtcagcaaca cctgcagtat caagtgcgcc
    20521 acgaacgata tggtaacgta cccctggaag gtcttttaca cgtccgccac ggataagaac
    20581 aacgctgtgc tcttgcaagt tgtgtccgat acctgggatg taggcagtta cttcgataag
    20641 gttgctcaaa cgtacacgag cgaatttacg aagggctgag ttaggttttt taggtgtcat
    20701 tgttccaaca cgagtagcaa cgccacgttt ttgtggggca gccattttag tttgaacttt
    20761 tttgtgactg ttgtaaccaa tgttcaaagc tggtgaatct gatttttcaa ttttagattt
    20821 acgtggttta cgtaccaact ggttaattgt aggcatctac attctcctgt gtttttttat
    20881 ttttggttga tatagcactt ggtgacagcc catatccggt gcactttttg caacaattgt
    20941 cagcacgtct ctgtacactt ttgagagacc aaaagtaaaa agtaccgtct aatataataa
    21001 cacagacggc acttcatgtc aaatagaatt tttcctttga tgcaattgct tatgacgaat
    21061 gcatcactta gattccttac ggaacctaaa tcctgtgagg ccgacagctg ccaacatgac
    21121 gactcctgct ttaagagctc tttgagtact ttcatcaaca tcagaaatga gattgctcgt
    21181 tgtagaagat cctgagccat aagatgtctt agatgagggc tgagtaatcg aagatgtgat
    21241 tttagacaca atggcattac ttgctaccat ttcagaggtt tggccaacaa gcgcttctgc
    21301 tacaagactt gtattttcag cagctaatct tgctgaagct tctaatagtt gtttcgtttc
    21361 tttaaccatt tcttgaacaa gcggagtagt atctatctta ctatatgata gcggttttac
    21421 gcccgtaaga ggtggagcta cttgcaaatc aggcacagta gctatatctt cgtctaagtg
    21481 gcgatattcc ttttcgttag ctaaggtttt aagcaaagtc aactggtgtt ctgtggtagc
    21541 aatagtagct tctagactgc tttgtttagc ttgtaaggct gctaaagctt cttgtgcatt
    21601 taacaaagat gaggtagttt tagccaaatc ttgcttagta ttatcaatgc gctcacgtat
    21661 cacttgaagg cggttaggat tcaatttaaa gtcccttaga tattgcaaat gagctttttt
    21721 agccaccagt gctgtcactc tggctgcggc ttgctctgct aaggcttctg tctggtgcag
    21781 tgcggctttc aacgatgcta gcttagctaa tgattgatca cgagtagctt cgagttgtgc
    21841 ttgttttgct ttagctgcta gtaattctgt tctcaaagaa cctttagtat catttaattg
    21901 tctcacttgg agatttaagc tgtctgactg cttaagtgtg cttgctaatt taccttgaag
    21961 ttgacttact ttagcttggg ctgccataat atcagcttct tgatgaatag ccgacaaacg
    22021 attttctaat gagcttactt ttcctttgat cgctgcaata gtatcagata cagtgcctac
    22081 tctttgggca taatcttttg tacttccaac ggcttttata ggggtcttat taaagcgttg
    22141 atggttagca atgttagact ctggaaacat tacaaagtgt tcattcaaag atcctacatt
    22201 gctggttgaa aatccaaggt aaacaggcgc attagggtta tgtttatcta cacgtaaaaa
    22261 gttaatagca tggccgtatg tatttccgtg taaatgatct gtaaagagca tatacttgat
    22321 actgtcataa ataccacgtt taataccatt cacagtatgc acatcgttaa aagcaccgat
    22381 attctcgtac atgttatcat catttcgaat gagccctgac gctccggcag agtcttcaat
    22441 aatagtttta tcatgaggcc caacaccata atgccctgat acccctggct gtccgtagac
    22501 aaatgatggt cttgtattac catgagtttt cttatagctg gtactaagta atcttgcaaa
    22561 ttcttgtgat cctgctgtaa cagtaactgg tggtagacct aattgtcttc ttacactatt
    22621 aatcatgtga gctgcaaact gcgctagctc attttgcact tctggtgtca aattatcggg
    22681 atcaacaaag cgattacgat ctgctggaat atcttggtat tgatttaatt gattacctgg
    22741 actagctttg gcaataattt gatctgcatg ctctttgtaa taattattgt aactagctga
    22801 tccaatataa ccactagctt ctaatttttt aagttcttca agaggatagc cttgcggtgc
    22861 tttcatggta ttattaccca caatgctatc ttgagtagac ggagctgagg atttaagacg
    22921 actaagttct gcctcttttt ctgctagagc agctttctga gctgccaact cttcagtcaa
    22981 ttgcttttta actttagctt tttgattttc taagtcagct ttagccttct ccaattctga
    23041 gcttaatgct tttgtattat cattagccgt ttgagctgct ttagtgatag catcaggatt
    23101 gctaatcata gcattgagct tagcaatatt ttgttcagac gttttgactt gttccactaa
    23161 atcttgagct cgagtagttt ctgctgaaat gctagctttt tgttctgaca atgcagtctc
    23221 ttttgaatgt tgatctgctt gagcattatg aagctctgtt tcagtagctg ttaactctct
    23281 ttgatgttcg gctccttggg ctaatagcgt ctcctcacta cttgcaagag tattagtgta
    23341 aatttcttgt gcagaggtta aagctttttg ttcattatct tgctgctctt ttaagtggtt
    23401 gatttcagca gtagtttttg tcagagcggt agcaagctct gtcagttctg ctttttgttg
    23461 actgagagtt ttttcaactg catcaatagt tgcctttgcc tcttgaattg tttctggttt
    23521 tggtaaacta tcgtcgtgag tattactcgc cttcgtttct cctgaggctc tatcatctgc
    23581 tttgacttgg tgagatacgc ctacactggc actcaataaa gcaattgttg aggttaaagc
    23641 aattttctgc ttaacttggt ttggcttcgt ttgttctaag tccattctct ctcctttttc
    23701 catttatcga aaatattacc aacttctaca acaacattgt tgtttttgac atcaatctct
    23761 gaaactttca gcaatgattt gaaggtcatt tgctcacgct ctgattgagc gttttctgca
    23821 aacacagcaa caccaactaa agtgctgtca aattctgtca agagactgat cattcctgta
    23881 atcgtccccc cgcccttcaa gaaatcatct acaatcaata cacgactatt gggtttcaaa
    23941 ctacgctttg acagaaacat cttttcaata cgatcactag aagcactcgc ataattgaca
    24001 gacactgtcg atccttctgt tatttttaaa tcacgtctaa caatgacaaa aggaacactt
    24061 aaaatattag ccactgcatt tgctaaagga actcctttgg ttgcaactgt catcacagcg
    24121 tcaatctttt ctcctttaaa ggcattggca ataatacgac caatattttg taaaatttta
    24181 ggtgtactca gcaagtctga caaatagata tagcctccag gtaagatgcg atcactctct
    24241 gataaccttt gacacaggtc ttcaacaatg gtacgcgctt ctgtttctga aatactgggg
    24301 gtaaaaatta cgcctccact tgctcctgta agtgtatcga tatcaccaat gttagcttct
    24361 tcaaaagctt tcttgataat agcgatatct tctgagatag aagattttgc ggcctcatat
    24421 ttagttgcaa aggtgtttaa actagttaat ttatacggat tgttaatcaa ataatttgaa
    24481 atgacaacca tacgttcact tcgtcttaat ttcatagttt ccccattttt atgtactttt
    24541 tgctattata ccataaagtt aataaaaaac gaacattcga ttaggaaaat attggttttt
    24601 ttgttcttat taatatcatg caagaattca atctaagata aactaatcaa cattcctact
    24661 gaaaggacat tctacttaat aaccataaca agagccaaaa acacttatga aaccatcata
    24721 agtgttaagc acatcaaaaa tcatcacaaa agcaaaggaa ctattactcg agaaacactg
    24781 atcaatagtt tggcttgtaa aaagaccgat tatccatggc aaaaatccga ttggtcatct
    24841 cgccctcgct aacacggcta agagctgttg tcatcatcat catattagca tcaatattgt
    24901 caatcatatg aataatttca gcttccatga tgcgtggacg taccggacta ccgtattcta
    24961 attgcccgtg atggcttaaa atcacgtgcc taaggacaat gacttcttct ttggtatcat
    25021 cgatttgtag ttctgaaatt acttttgtaa tttcttcgtt aatgagagaa atatgcccaa
    25081 tcaagttacc acgaacggtg tattctgtat tatctggtcc tgttaattct atgactttag
    25141 ctaagtcatg taacataata cctgcaaaca gtagactctt atttaagtca gggtagatat
    25201 ctccaatgct atctgctagt ctgaccatcg tagcagtatg gtaggcgagg cctgactcaa
    25261 aagcatggtg gtttgtttta gctgcaggat aagtataaaa ttctttatca tacttacgat
    25321 aaagagccct tacaattcgt tgccacgttg cattttcaat tttaaagagc atctgttcca
    25381 aatagtcacg tacttctgtc acactgacag gtgccttttc tttgaagtcc tttggatcat
    25441 tgggctcacc tgggcgaaca tttcgcaagg tgatttgatt aacctgaggg gtaccattat
    25501 acacctcgcg tcgccctttc ataaacacga ctttaccagc agtaaattct tcaacgttat
    25561 aaggttgggc atcccacaga tttcctgaaa tctcgccagt gtcatcctga aaggtaaggc
    25621 taataaaatc tttaccagct cttgtcttac gaacctctgc cgacttaatg aggtagaacc
    25681 cttcaaaaag ctggtctttt ttcatttgat taattttcat tattttcctc ttctaataag
    25741 ggcatgttca agagagattt tgttgcttgg tcttgataag tttcaacggt attcaaggct
    25801 cgaacaatgg catttgtcct tgttgaaatg agctgatcca gcgtattatt agctgtattc
    25861 atttgttttt gagccttggc aagcaggccg ccaaatttat cgaattctaa cttgacattg
    25921 cctaaaattt tactgatgtc atcagcattt ttttggatat taagggtctt gaaaccaaca
    25981 gataaggaat tcagcaaagc agacagggtc gaagggcctg caaccacaat attttcttcc
    26041 cgacgaaggc tatcaaagaa agacgcattt ctgaccactt ctgaataaag accttctgtt
    26101 ggtaagaaca taactccgaa attggtcgtc tctggggggt tcaagtactt tttatgaatg
    26161 tctttggcaa agcgtttgat agctgccaga agtgcttttc ggctagcctc gatggccagt
    26221 ttatcaccaa cttcgtaagc atcttctaat cggtaataat cttcaagagg gaattttgag
    26281 tcaatcggta ggtaaatata accgccttga ccatttcctg ggagcttaat cgcatattct
    26341 acgcgttcac tagaaccact aaccgttaca aattctcttt cgtactggct tgatgtcatg
    26401 atatcctcaa tgatttggcc tagttgaagt tcgcctaaaa tgcctcgtgt tttggtattg
    26461 gacaaaacct tatttaaagt acccacatct tgagccacgc tacgcatttc tcccaagcct
    26521 ttattgacac tttctagttg cttggataca gaatcgaaag aggcgtgcag acgatttttt
    26581 aaggtttctt ccaatttttc ttcaacgatc tggcgcattt tctccaaacg tttttcgtta
    26641 gattcttgca tatttttgag cgattggttg acctgctggt taattttttc taagcgtttg
    26701 tcagaccggt ccctactatc agacaaacta cggtgcaaga cgtcacgaat atctgttaat
    26761 tgttggtaaa ggcctgcttg ttgtcggttc atcagctgtg ttagctctaa caattgttgc
    26821 ttgttagctg tatccaactg gtaggtcatt tggtcagaca aattatccgc gttgccttct
    26881 agggtttggg caagctgatg ttgaaggccg ttgactttga acaacagata agcccctaaa
    26941 cctaagagaa ccaagaccaa aaggaacaag ataaggtcca tactaactcc aatctttact
    27001 ttgaataata atcaagtagc cacttggcaa actaactgta ataggttgat ggataaaggc
    27061 attactggaa tagattttct ttttgaaaaa attatcttgc gtcaactcaa atttagcacc
    27121 agtaatggtc aagtcagctt ctccttctgc cataaatgcc acataggtca tcccttcttc
    27181 ttgatggata aggtgctgac ctgccgggcg gtaggtaatc atattttgtt ggtcacgcaa
    27241 ggcgatttgt gccataaagg gagcaatacc agggtcgcta ggcaagaaaa tattggataa
    27301 gaggtggtcc attcgacccc caaaagcccc aaaaatggtc acttccgcct caggaaaacg
    27361 agcaaagacc tctttaaggg ctaattccgt atccgtatca tttttttctg gatgagcagt
    27421 aataaaaagc tctgccttct cttttatatc cgtaaacgct ttttgggaaa ccgaatcaaa
    27481 atcaccaaca gccatattca aaggaagccc attttctaat aaaaataggc tccctctatc
    27541 aataccgaca aaataatcaa aatcacggct gatataagag agatctcctc ccgcaaaaag
    27601 agcaacttta gacattcaag gccgtcctta aggtttggac ttggctcact aggtcactgg
    27661 ccttgaaaag gtaagaacct gccacaaaga cattggcccc tgcttcataa caagcacgaa
    27721 tggtcttatt gtctactccg ccatcaacct caatgtcaaa ggacaatcct ttttcatctc
    27781 gccatttggc tacggtagcc actttttcta aacattctgg gataaaggcc tgacccccaa
    27841 aacctgggtt gactgtcata atgaggactt ggtcaactaa gtctagcaaa ggttctaggg
    27901 ctgttgcagg agttcctgga ttaatcacta cccctgcttt catgccagct gccttgattt
    27961 tttgaagggc tccatgaata tgacgagtac tttctgtgtg aatggtcatg atatcagcac
    28021 cagcttgtgc aaaagcctca acatagcgtt caggatcaac caccattaga tggcaatcaa
    28081 agaccaattt actgtgcttt ctcatacttg ccacaacatc tgcaccaaaa ctgatgttag
    28141 gaacaaattg accatccata atatcaatgt gaacgtattc ggcatctgtt tcttcaatac
    28201 gagctagctc agaagcaaaa ttagcataat cagctgctag aatagatggg gcaattttta
    28261 gagttgacat ggagtagacc tactttcttt tgataacttt tttatatgtt tcacgacggt
    28321 tttcaatttc actgagaaat tgcaggtaat gctcataacg aactggccac aactctcccg
    28381 tttcaagcgc tgccttgaca gcacacttgg gttcgtgggt atgggtacag gatctaaact
    28441 tacactcatg gctcagccgg cgcagctctg gaaaagcctc gttcaaatct tcagcattag
    28501 caatatcata gtctaatgat gaaaaacctg gcgtatccgc gatttttccg ccatgggtat
    28561 tgtaaaaact cacagctcgg gtggtgtgac gaccacgccc tagactatct gagatttctc
    28621 ctatttcaag agccaattcg ggggcgattc ggttgagaag ggttgatttc ccaacacctg
    28681 tttgtcccat aaagacggta attttatcag ctagcaaagg cagcaattcc tcaagactgg
    28741 tcacaaaatc gtaaccgatt gcctgatact gtcgaccaat agccttaatc tcctcgggac
    28801 tatctaataa gtccatctta gagatataaa ccactggatg aatggctttg tgttcaagca
    28861 agatgagaaa gcggtctaga agattgctgt taaattctgg ttctttagca gacataataa
    28921 ccactgcttg atcaatattg acgataggag gtcttaccaa actgttttta cgaggatgaa
    28981 tcgctaaaat ataaccttca gagttgtcct ctgctgagaa atccacgata tctccaacat
    29041 aaggtgtctc accgcgcttc ctaaaattac cacgcgctcg cgtctgatat acctgtcctt
    29101 ctgactccac gtaataaaaa ccagccagag atttaatgat tttaccttgc aactgtgctc
    29161 ctttgcccta ctataataac tctattatat cagaaaaccg ctcccaaatc agcatttgag
    29221 tctaagtttc actcgcttta aaaactgtca agattctcta gaccactggc tatcatttag
    29281 gtcactgctt tttaaaaata gaatatttta tcaactaaaa atcagatcac tgatgatttt
    29341 ttgaggtagg aaacgatatg aattttaaga agacctttgc tatttacgaa aaagagtcta
    29401 accgtaccgc tatagtcacg ctcttgttaa ttgccctttt tttccggggt attaaaaaaa
    29461 ctagctctgc actgcgatgc cttaacggcc agcttcaata agaaaaatcc ccctgaactg
    29521 aacatctctg ttttgtctac aagggaattt ttttattgtc accgggggaa agcttttata
    29581 atccaacttc ttttaaagca tcagctaatt tgccaaaatc ttgaatcgac aaggcctcac
    29641 cacgaataga aggcttgata tctgctagtg ccagaccttt ttcaagttta gccttgatgt
    29701 cttcagactt cccaaaatgg ctagtcaagt tattccacag ggtcttgcga cgatggacaa
    29761 aactgagacg agacactctg aaaaagaaat cttcgtcctt aacctcaatc aaaggctggt
    29821 cgcgacgcac cattttgagg atagcactat cgacatttgg tgcaggtaca aagacggtgc
    29881 gcggcacaat gaaggcaacc ttggcagtca tgtaatactg caccgcaatg gacaaggaac
    29941 cataagcttt agtgtttggc tccgcagaaa tacgatctgc cacttcacgc tgcatcatga
    30001 ccacaaactc ttggaatgga attttgctct caatcaagtg catgagaata ggcgttgtga
    30061 tgtagtaagg tagattagcc accaccttaa tgggcaaatc aggattttta aactgcttga
    30121 tttgggtctg caaatcagct tttaaaatat cttgattgac cacttgcaca ttatcaaaat
    30181 cgcgcaaggt atctgccaaa atcggcacca agcggtcatc aatctcaaaa gccatcactt
    30241 cagcagcatt ttctgccaaa aattccgtca aagccccaat tccaggacca atctcgataa
    30301 cattgacatt ctgatcaatc tcagccgtgt caacgatttt ctgtaaaata ttggtatcgg
    30361 tcaaaaagtt ctgaccaaaa gatttcttaa aggtaaatcc gtgacgatca aggacagcct
    30421 tggtcacgct ataatctgca attctcatat attctcttct ttttatgatc actttctttt
    30481 tggcatttga accactagcc taaacttttt tgccaggaca cgccattcag ttaatggggc
    30541 tgttatattt tattgtactc tttactcctc atatgtctcc atcacttctt ccacttctgc
    30601 tagggtaatg ccaaataatt cgaggcgctt gagcagttgt ttgccgttgg cataaccgat
    30661 gcggagcttt tcacccaagt attccctgcg tttacggcta tctgacgcca ttaaaagccc
    30721 tagacgaatc aggtctgttt gacgaatgtc aaaataagac tcatcatcat attgctgagt
    30781 gacatgagca agtgcctttt ggagatcctc aaaattggca tgttcaaccc ctaaggaacg
    30841 acccttactc ttagaactcg gaaccgcctc gtttcggttt aaaaaggcat gacgagctgt
    30901 tggcacagca gccataatga gcttacgaat gcgctcacca ttataatctg ggtctgttaa
    30961 aacgataaca ccacgcaaat cgtttaggcg attgattcgt tctaaatctt cttcagtgat
    31021 agcagagcct ctagtctcat aggtatccac ctcgtaaaaa cggcgtaggt tagccgtgtc
    31081 gtccttgcct tctacaacaa gaacctcttg aatattaatt ttttcagtca agcttgaata
    31141 ccctctttgc attagcagtc gttgcttttg caacttcttc cacagtcatc ccccgtagct
    31201 ctgcgatttt atcaaccaca tagcgggtat aagctgtatg attttgtttg ccacgttttg
    31261 gaactggtgt aagataaggg gcatctgttt ccaccaaaat cttatccaaa ggcaagtgct
    31321 gcgctgcctc ttgaatatca agagcctttt tgaaagtgac cacacctgaa aaggaaatca
    31381 tcatgccaag ttcaatgaaa cgttcagcca tctctaatga ccctgagtaa gaatgcatga
    31441 tgcctccacg agggccaaca ccagctgctt tgatgacctc ataggtatct tccaaggcat
    31501 cgcgggtgtg caccacaaaa ggcaaatcat ggtcttttgc taattgcatt tggcgcttaa
    31561 aaacctctat ttgcacctct ttggggtcct ccatccaata atagtctaag ccaatttcac
    31621 ctaaggcaat cactttggaa tgtgataatt gagagacgat agcctcctca acagcctctg
    31681 aataagaacc tgcttctgtt ggatgccacc caatagttgc ataaatattg gcatatttat
    31741 tggctagagt tagtgcccca ctaatagtgg cctggtcaaa gccaaccaca ttatggtagg
    31801 ccacgcccat ttcttgagcc aaagtcaatt cttcagtttc gtgtccttga aattctgcta
    31861 cattcaggtg cgtatgggta tcaaaaatag ttagtttttc tactttattt gtcatgatgt
    31921 tattataaca taaagatctt aaccacatca gaaaacttgg tgagaacttc tgccgtttag
    31981 gttgatcgta aaaccctttg ctagctgaca cttgtctatt ttctactttt ttgacaaatg
    32041 acctttaata gtcggctcct acataagccc tcaaaaatac tacaacctac tcaaataaag
    32101 tgggttgaac aaatctgtat cacaaaaagg gtcgctacct tctgttagcg atctatgcta
    32161 tactagtagg tagttaaact gtaaggagtg tgctttgcta tgcctaaaaa ccaccgccta
    32221 attaccaaaa tcgaagcatc attggaacat atgaccagtt tagaaaaagg gattgctcat
    32281 ttttttatta caaccgatct gacacctcaa gagttgaccg catccgagat agttaagcga
    32341 ctacacatct ctcaagccgc cttgactcga tttgcaaaaa aatgtggttt tactggttat
    32401 cgtgcttttg cctttgatta ccttcacagt cttcaagaat cacaagagac tttccaatct
    32461 attcacttag aattgacaaa gcgcgtgctg atggactacg acgctcttat taataaaacc
    32521 tatgagctcg ttaatgagga aaaattactg aacttagcca agctgatcga ttcttctgag
    32581 cgagtctatt tctttggcaa aggatcttct ggactagtag caagagaaat gaagctacgc
    32641 tttatgcgac ttggtttaat ctgtgatgct tattcagaca ctgatggttt tacttgggca
    32701 aatagcctcg tcaatgaaaa ttgccttgtt tttggttttt ctttatctgg caaaacaaac
    32761 tctgtcatca cagcacttca tcaagctagt cagcgaggag ccaaaactgt cctcttaaca
    32821 acagataatc aaaccgaatt tgacgactcc ttagatatta ttcccgtatc atcaactcac
    32881 caactacatt atgggaatcg tgtgtcacca caatttcctc ttcttattat gatggacatt
    32941 atttatgctt acgttttagc gattgacaaa ccgcacaaag aaaaaatctt caaaaacact
    33001 attattgaca aagaaaataa cgacctttag actacaatag caaaaagggc gttgttttct
    33061 ttttaaaggg tcgtcattca cctcccccag tatacttaaa caagaactct tcacgtcata
    33121 tagactcaca gccactaaga ttagctactc gctaaattat tttcgatttt ctcaagagtt
    33181 ataaatgaac aagatcgctc attcttttgt ttaaaatggt agtaagctcc taatatacca
    33241 gcattatttc catgactagc aaacttcagc tgagttttct tggcaagact agaaaccaag
    33301 tagctatcaa gagctgtctt taatttatca gctaaatagt ctttttgcgc catgataccg
    33361 ccaccaagca ccaccacatt tgggttaaca acgtagcaga tattagcaat accttgtcct
    33421 aagtaatcca cctgcttact aatggctgct atacaaatcg catcacccgc tttagcctgc
    33481 tcaaaaatac gacgaccatc ccattggcta atgtcatcgc cataagctaa gaccacctct
    33541 tgaacaagag ctgtggtaga tgccagatcc tgaaactgac catctgacaa atgaaggtaa
    33601 ccaacttcgc aagctgaatg actactacca tgaaaaactt gggaattaaa caataaacag
    33661 ccaccgattc ccgtcccaat tgtcaagcaa agagccacag gataatcctt ggcactacca
    33721 gaaatagctt cggccagacc agcacagtta acatcgtttt ccacttcaca cggtaacccg
    33781 aaagtctctt caatctcttt tttaaactga gttccagcat agttaggaat ctgagggccg
    33841 gcataaaaga tttctccctc atcaggatta accattcctg cagaagaaat ggccactcca
    33901 gccagatcca tttggtcttg ataggtcttt accaagccct tgaccttttc caaaatagag
    33961 ggaccacctt tataagcctc agtggccatt tcctcttttt ccaacaggtc tcctgtttca
    34021 gaaatcaagc catacttgat agcagtacca ccaatatcaa ttgctaaata atgcttcatt
    34081 tgttatcccc tcgcatctta tcaaaaggtt tccttagcct gattaatcag agcagcagcc
    34141 cgttggcaaa taaccctatc ttcctcgacc aactcagcta aaggtgatcg aacagaacca
    34201 atatcaagac cctcattaat acgaagtact tctttaataa ccccatacat attgccgtga
    34261 gcagaaacaa ggacaccgat aatctcatta atagtatatt gaagggcctt ggccttttct
    34321 aaatccttgt cagcaataag ttggttcagc cttaaaaata attctggcat agccccgtag
    34381 gtaccaccaa tgcctgcagc agcacccatc aagcgccctc ctagaaattg ttcatctggg
    34441 ccattaaaaa caatatgatc gtccccacca atcgcacaga aggtttgaat atcctgcact
    34501 ggcatagatg aatttttaac gccaatcacg cgcttattag ccaacatagt cttataaagg
    34561 cttggcgtca aggcaacccc tgccagttga ggaatattat agatgataaa atctgtgtga
    34621 ggagcagccg aagaaatagc attccaataa tcagcaaccg catattctgg taaccggaaa
    34681 taaataggcg gaatagctgc aatggcatcc acgcccaaac gttctgaatg agctgccaat
    34741 tcaatactat ctttagtgtt gttgcaggca acgtgattaa taatcgtcag cttgccctta
    34801 gcgactgcca tgacattttc taacaccaat tgacggtcaa aaacgctctg gtaaatacac
    34861 tctccagaag agccattaat gtaaagcccc tgaacccctt tgtcaatata gtactgggtc
    34921 aaggcacgca cacgctcagg gctgatattc ccctggtcat cgtaacaagc gtaaaaggca
    34981 ggaataatgc cttggtattt cgtaagatct gtcatagtaa tgtcctttat tcaatgtcat
    35041 tattaagtgg gaatcgccta agaagagatt ccatgataat caagtagaga taagttagac
    35101 tactgatgcc gatgatagct agcaaagaca cgcctccaaa taacgttaac agagacaatt
    35161 gtaggctaaa tatcgtgaga caaataaaag ccaagaaagc aaaactccat ggaaaaaaga
    35221 gtcctgctaa taaaaagctt cgcttaaaca gcgtagatag ggaaaggtct cttttgacgg
    35281 cctgaggata agcgtacaaa aagagtataa ccaccaaaaa taaaacagca acgcaaagta
    35341 ctttaaaccc ttgaaaaact aggcctgatt ggtttcgaat taagaaaaga tctaagagac
    35401 aaatagtcat tatcccaagc tcaataaggc caaggcgtag cccactttta aagtaatatt
    35461 taaaatgaga gctataagta gtaacaagct gactaacttg accttctcgc caatccaaca
    35521 aactcgcata caaagccatt ttagcaaccc caatcgttag aaggggaagg caggacaaga
    35581 caaataagag attaaacacg agcaaatcaa acagtgctgc gctagccctc atccatttac
    35641 tatcaagctt gaagagagag tgtaaaagtc cctgtttttt cgatgtcaaa tcacaacttc
    35701 ctttctagaa atacgcttac aaacaaaagc taactctcct cttaaacgtt taacacatga
    35761 cttgcttccc atctgattta tctatgtatg cacctaaatt aataagcaac ctatagatta
    35821 agcttagcga cacgctttat ttagtctaac ctttcacagc acccatagta atgccttggg
    35881 taaatgattt ttggaagaca agaaagactg ttacaatagg cactgcagcc atggcagccc
    35941 ctgccataat caagccataa ttagtagcca tttcagcttg catagtggca accccaagtg
    36001 aaatcgttaa attttctcga gaggttaaca tcactaactg cataaaataa tcattccaag
    36061 tattgataaa ggtaaaaatc gctagcgctg caaagcctgg tttgacaata gggaaagcca
    36121 cattgaaaaa ggtacgaatt tcgccacatc catcaatctt ggcggattcc aataactcgg
    36181 ttggaatatt ttctgagaac tgtttcataa ggaaaacacc aaatggccag cccacaagag
    36241 gcaaaataac agccgccaaa gtgtcatgga ttcccataaa attaacaatc cgcacaagag
    36301 gcactagaac aacctgtttt ggcaaggcca tagcagcaat aaaaatcgaa aacaaaagcc
    36361 gctgtccata aaaccgcttt ttggccaaag catagccagc caacgaggag gttccacaaa
    36421 ccaagaacat ggtcgccacc gaaataaaga cactattcca caaccatttt aaggctggat
    36481 tttgcactac caaggcctta aaattttcaa tagtaggcgc ctttggccac cattgcggtg
    36541 gaatcataat ggtatcggct tgagccttaa atgctcctgt cataatccaa taaaatggaa
    36601 aaataaacaa aatggtcaaa acacatagca tcacagtggt taagatatct gatgcggtta
    36661 gtttcttttt cgtcatctta atatcctcct aatattccac atcattacct aaaattttaa
    36721 attgagcaaa gctgatgatt gcaatcatga ctgccaagaa tacacccatt gtgttggcat
    36781 agccgtattc agagagctta aaggcctttt catacaaata gtacatgagg gtactggttg
    36841 aataatttgg ccctccagac gtcaaaagtt gaatcaaagc aaaacattgg aaggaattaa
    36901 tggttgttat gacagcaata tataaggttg ttggcagcag acttggccac ttgatattcc
    36961 aaaacacctg aaattctgtg gcgccgtcca cacgcgcagc ttctaccaaa gagttatcaa
    37021 tatttcccat agcagcaata tatagaataa taggctgccc aacagatgtg gttaataaaa
    37081 taacaataat agccaacaaa gcccagtgct tatctcccag ccaactaata ttttgttcaa
    37141 tcacatgagc atattttaag acataattca aaatccctga cattggatca tagatccatt
    37201 tccaaaccac cgtcaccgca acacttccgg taacaacagg cagaaagaaa actgcccggt
    37261 aaaacgaacg cgccactaca tttttgtcgt aggttttagc cgccacaaag agggaaaaga
    37321 aaactacaac aggtaccgaa ccaataacaa taatcaaggt gttaataaga gacttcatga
    37381 aaatgggatc ttgaaacatc ctagcataat tagcaaaacc aacaaaggta aactctgtca
    37441 tggaataatt gaaaaagctc gtcacaaagc ccataatcat cggtatcaag acaaaaatca
    37501 caaagaaaac caagaccgga gctaagaaag cgtatgagat gagcgtctct ctcattttta
    37561 atttattgac gttcacttga aatacctctt ttttctgttc aacttttcta aaaagaaaag
    37621 cttctttcca gtgaccattt gacatgtgca ttgaaaagaa gccacttgtt aggaacactt
    37681 attgtgtttt tttgattgtc ttgtttgctt tttcagtgaa ggctttcaaa gcatcttctg
    37741 gcttttcatc accattagag acggcttgaa ccattgggaa ccaaagagtt ctcatttcag
    37801 caaacccatc aatcgtgtta tagtatggtg agtagaattt tgtccattca gcaatttttt
    37861 ccattcgttt gtctttgtaa agatccccat aagaagttct tacagggaaa gcacctgtac
    37921 gaacaacatt tttaggtccc cattctttat catcagcgat aaattggata aatgtcttag
    37981 aggcagcgac tttttgttca tctttgttat taaagaccgc aaaaccattt acgaggtatt
    38041 ctagttctgg tttgccatca tctgatggga atgggatttc aaggtaatcc actttactag
    38101 cttctaacaa tttagcttgg atgcctggtt gtgcaggcgc ccaaagaatg gtaaaggaag
    38161 tttggccatt cgcaaagttt tgaatatcag ctgaaccatc gtactgagag ccattcatca
    38221 ttaaaccatc tttaatccaa ttggaaatct tggtcatggc tttaatagag ttagcatcat
    38281 ctgtggtgta tttggttact ttgtcatcgg taatatgact actataaagg ttagcaaaga
    38341 aggcacgtgg tccttggtca ccaccttgac cattagcaaa gaaagaacct gggttatatc
    38401 ctttgtcctt caatgctttc aagacttttt caaaatcatc tgttgtccaa ccctctttca
    38461 caagatcaag gacgccagca tctttgagca tttttttatt caacgccatg tagaatggag
    38521 cagagctgat aggatacatg taagctgtat ctcctgcttt tgaggcttga atcaatttgt
    38581 cattgttaac atctttggta aactcttctg tgaacaagtc attcaagtca gccaatttcc
    38641 catttttacc atattgaatg atacgacctg gagcatcaaa gaggacatca ggagctgttc
    38701 cagcttcaat agcagttgtg attttctcag gaccagatgt aaaatcaatg gtttccaatt
    38761 ttaccttgat ttctggatta gctttctcaa aggcagcaat caatttcttc tcataggttc
    38821 ccacaccatc ttcagctttt tcttgcgtga agaccgggaa agcccaccat gtgatttctg
    38881 tcttagcagt atcagattta cttgcaccag cctctttctg gctctttccg ccacaagctg
    38941 ctagtcctaa aacagatgca ccaagcatcg ctaatgaagc taacttcttc atgttcatcg
    39001 taaaatctcc tttttttgat gtgtgtttct agtttgacaa ccactattag gatttgagcg
    39061 cttcgataaa acgctctgca atttccttag gccttgtgat ggcccctcca acaacaatac
    39121 ctgccacacc taagtcatta attttcttgg cttcttctgg ggaatgaatc tttccttcgg
    39181 caatgacagc aatgcctgct ttgcaaagag cttctatcaa tgccacatca ggacctgctt
    39241 cctgacggct atacggggtg tagcctgaca aggtggttcc aacaaaatca atgccagcct
    39301 gatgggccac tagtccttca tcaaaggtac taatatctgc catcaaaagc tgattggggt
    39361 acttttcctt aacttgtcga ataaagctag caatatccaa gccatcatgt cggtcacgct
    39421 tggtacaatc catagcaatc actgcaatat ttaaggcagc taattgatcc acttcggtca
    39481 tcgttgccgt aataaaaggc tcttgcggcg ggtaatcttt tttgatgata ccgataattg
    39541 gtaggtctgt tatggcttga atttctttaa tgtctctaac cgaattagct ctgatgccga
    39601 cagcaccagc ttcttgagca gcttttgcca tcagtggcat aataccccca gtctctgaat
    39661 agagaggctc acctggcaaa gcctgacaag aaacgataat cccacccttt aactgctcca
    39721 tgagcttttc tttggttggt ttatcaggca tagtttctac tccttgtgtt tcttagtttt
    39781 aataaaaata acgttcacaa agttattata acaaaaaata aagcgctttc aatagcaatg
    39841 agacttttag aatctacttt cattttttat attattttct attatttgga atgctctttc
    39901 atacaacaaa taaaaaggta aggagttgac accatactta tacattgcaa atttccgatt
    39961 agaaaacgtt aaaaaaccaa gagcctcgag cactcttggt ttactttagt tgtatttttt
    40021 gcaattaagc tgataatact ttacgtcctt tacgacgacg tgcagcaagc acgcgacgtc
    40081 cgtttttagt tgacatacgg tgacggaatc cgtgtttacg ttgacgacgg attttacttg
    40141 gttgataagt acgtttcaca gtgaatacct cctcatagat tttgtattcg tttagccggc
    40201 tatttgtgat atcagttact aaacatacta taatattcta tcttaaagag ggtctactgt
    40261 caagatttat tttcgttttt caacagtttc tctctcattt aagaggccgc tcatttcata
    40321 aagtgtctct tctttgacac tgttcctttg ccttaccgtt gaaaccttat caatagcaac
    40381 aataatcaat gagatcagta aaacaaacgg ttaagctggc catacaaaaa atcttcgata
    40441 gctaaactaa ctaccaaaga ttctttttag gatctaacgt tgaagactga ctaccacata
    40501 gcggttaggg tcattgcctt cagaataact atcaacccct tcaatggatg aaacggtttt
    40561 atgaacgatt ttacgctcac tgttactcat gggatccatg gtgtaatctt gaccagattc
    40621 caaaacgcgt ttggcaactt tttgcgtaaa gtcaatcaag gtttctgttc gatgttccac
    40681 ataatcatgg acattcaagg atactgaaaa attttttgaa tagcggtcgt gcaagaaatt
    40741 ttgagctaac aactgcaagg atttcaagac cttaccatgg taaccaatca cacgtcccgc
    40801 ctctggcgtt tcaatctgca aattgatttg gcgacgattg ttgctggttt caacggtagc
    40861 ttcgatatcc atttcataga taattttagt cacataatcg gacacttcct gagcagcttt
    40921 ttcaatatct ttgctgaaac catcattacc agcatcttgg ggcacttctg attcttcgac
    40981 tgggattgac ggttgttgtg cttttgtttc agtgactgtc tcagcaagat tagaaggggt
    41041 ttgcgctgga ctatcttcag acatgagagg aaccactttg gtatcttctg cttctaacct
    41101 ttgagtggct tttatttctt caggttctac atcagcagaa ttgaccgcgg gagtattttg
    41161 acgattaata tcctctggaa cacctcgagt ggctttttta tcagccttat aaaccgtctt
    41221 gtcgctgata ccttcgatat caacttgggc tggcttttta ccaaacccga ggaaaccttt
    41281 tttctctttt gaaatgactt tgatatgcgc tttaaggcgt gataacccta actcttgaag
    41341 tcctgtttcg atagcttctt cgactgtttt tcctgtaaat aataccataa cctaaactcc
    41401 tattttctct tcattgcttt tttacgagca cgacgttcac gaagacggcg ttctttttct
    41461 tcattggcaa gacgttgtct ttccgcaata atcttaaaag gattgtttaa taacagtagt
    41521 tgtaccactt gaaaggcatt ggagaccgtc caatagagca ctactccact agccaagtta
    41581 aagcccatga aaaagatcat tagcggcatc acataaatca taacagtcat catgacattt
    41641 ttttctttag ccgctagatt ggtcaaccaa gtggacaaga aagtgaagac agctgccaaa
    41701 actggtaaaa ggtacaaatg atcatgttgt gccaattcca cccacaagaa agtccctgtt
    41761 tttaagaaag atacccgtgt caaggcttgg aataaggcaa tcataactgg catctgaatt
    41821 aagaggggta agagactagc ataagggtta accccatatt ttttgtaaag ggcttgactt
    41881 tcttcagcca acttcatccg cgtttgtgtg tctttaccag cgtatttcct ttgcaattct
    41941 ctaagctcag gttggatgtc ttgcatcttc tggcttgatt tgatttgcat gttaaacaaa
    42001 ggcatgagca tgagacggat agtaagggta aaaagaataa tgccaacacc aattgaacca
    42061 tcaaaggaaa gccattgaat tgctctggca aataagtaaa ccaactggtc ccaaccacta
    42121 gatgattgtg ccgttacctc accacgacca caggccacta ataatagaac taaggggact
    42181 attcttgcaa ttttaatgtt tttcttcact ctcaaaacct ttctcaagca attgtgctaa
    42241 ctttaaaaca tgatgtaaat tttgttgaag ctcttgatac tccaaagact cgacaccctt
    42301 acgggcaatc accacgaaat cctctgactt cagctgatgc cctaatgcca tgataacatg
    42361 acgtatcttt cgtttgactg catttctggt gactgcattt cctatttttt taccgacaga
    42421 aatacccaca cggaagtggt cttggcctct atttaaatga taaatgacaa attttcgatt
    42481 tgctgtactt tttccatcct taaatatggc ttggaaatct ttctcacgct tgacacgata
    42541 ggtcttcttc aaaatttaac tccaatatct aaattattac cattatacca catcccctaa
    42601 aaaattaaaa agccctaacc ctttcagatt aagcctcttt ctgtactatt tctagttttt
    42661 gtgcttcaac tgcctcttgt cactccatct tttcgtagta tagttcttct ttcgacaaag
    42721 gaataacctt cagaaaacaa ccataaaaag tcagaatcca caagacgtca gctacttatc
    42781 cctgtattta cctatcaaaa aacccggcaa gccgggcttt aatactgatt ttacaatcag
    42841 ctaatgtgat atccaaacaa agacaactga catcgtcatt ttgtctgccg agccatcata
    42901 tcaaaaatac tatttgttta tggagagaga gaaaacaata ttttgattga attggggatt
    42961 gattgctcga taaactcatg acttcgtaaa tctttattta cactaattat tatagcgaaa
    43021 aatgtttcaa taagagcatc atttcctgaa atgttgcttt ttcgtcctaa aatgttattg
    43081 ctctcttaac tttagcgaag agcctcccac cgttcaaaca gacatttcat ttttaatcgt
    43141 gataccatac aagaatcacc attttcgaaa taaaggagct gcttactctt atcaattcga
    43201 acaaccttat ctagattcac aaggtaggat ctatggcaca aaaaaagttt cggtgctact
    43261 gcttgaatct cagatagatt accataaaac tctaatcttt ctgtctgagt ccataaacaa
    43321 actttgtgag gagttgtggc tgtagcaaag tataaaatat ccttataggg caattttaat
    43381 cttgtctgtg gagtctcaaa taaaaacatg tcctttgact cacgactaga catcatatcg
    43441 taagtatatc ggatacattc ttcgatttgt tctttaaact gtttttgacc acctgcttta
    43501 tcaataaaat ctagagcgga taccttatat ttaaaagaaa taggagcaaa ttctgaatga
    43561 gtggtgacaa acacaataac ggcattagga tctttttgtc gaatagctgc agctaattca
    43621 agcccacaac gagtatattc accaatttca atatctaaaa aatacagctg atggtctcct
    43681 ctttcttgga tactctcaaa taatttttga ggagtcgaga acacttcaag ctgattacat
    43741 ggtattctag tctcttttaa gatgcctact acgatagatt ctatgcgtgt ctgctggata
    43801 aaatcatcct caagaataaa aatgttcatc atactttatc tcatttctaa caattgtctt
    43861 aatcgataat ggtcactttt agtcgaaagc gttatttggg ggtaactatc taaaacagtc
    43921 aaaaagtggg ctgagttctg ctgctgagca tcaaagcgtt tggctatatc cacacgattg
    43981 gtttttgtgc tattttcaat aataaataat tgcttgttat cttgtttaaa gtatgcaata
    44041 gataaaaaag gacgtctact gcctttggct gtctcaatag cattgtccac tagtccagta
    44101 aaaagtacaa ttaagtcgat taacttaata ggtaaatgat cgataacatc tggaatctca
    44161 atataaagtt caatacccaa atactgagct tcaagcaatt tggaattcat gatactgcga
    44221 atcacagcct ctttgatatt gtctaaagaa gatatttcat aatttgtgcg catcatagaa
    44281 gttgccgatt gctgaataac cgtgtcataa actctagtaa tcagatctat atcaccacta
    44341 tcgatactat cttttagact aattaaaata ttttcagaat catgtttaac tgttctgatt
    44401 tctcggtaaa gttgctcaat cgattgattg taattttcaa gatacgcaat acgttcattt
    44461 tgtgcttgtg ttaatttttg tgacagctga tctttagcaa atcgatctaa tttcacaata
    44521 acccaaataa aaatagctaa ataaataaat actaaaatag accggtactg gaaatatagt
    44581 gcaagaaatc cgctttgcac agttaccaaa aaatgggcga aaaagtagta agaaaacatg
    44641 gcagtattca tccaaaatac ccactttttc atcttatctt cactgataaa ccttattaag
    44701 cttaagtcaa tactgaaaat gtagctaaac agataaaata ttggtaatac aaaaagataa
    44761 cataactcta aaagcttaag gttattatta atttgaccaa tgctaaatcc taagacagct
    44821 ggtaaaaaga aagatccgat gacgcgaaac agtaattcga caatcaagat agtaaagaaa
    44881 ccattaaaca tatgctcaaa taatttcttt ttcggagcac ttaacaaact aacaataata
    44941 aagaacagtt ggtcaatcaa aatgactttg tcaaatatca tattagcaat tacaaaacta
    45001 atgcctataa tgctaacccg tttccagctt agtttaatag cagaaacctt tgcaaaaatg
    45061 acccagctgt taataaagat ggtagcatag aataaagcca tactgtatat aaccatcatc
    45121 tatccacctc ctcctttggc atggtcaagg tttggctaaa ttccttatca aaacttttag
    45181 tccgcaagga taaataagga tactttttga gaatacgctg cgcattagaa aggccgatac
    45241 cacgttctga accttttgaa gaatagcctt cttcaaagat cttgttaatg tctacctttt
    45301 ttttagtcgt atttgtcaca acaaacatct gatagtcacc taacaaaaag taagcaattg
    45361 acatatgagg ttgttgtgct tcaagagctg cctcaatggc gttatcacaa aaaatagaca
    45421 tcaacaatag taagtccaac tcaggaatgt aagtctcttt tatattatct ggcacttcca
    45481 cattcaaatc aatacctgat ttttccgcac tgataatttt agctgacaat aagctcttaa
    45541 tcgatgagat attaattttc ctaagcttcg agatattata gtgtttatca tcccagtagt
    45601 cgttagcttc atgaaccgtt tgggcataaa tatcttgaat ctgagtaatg gattcactct
    45661 taatggcttg acctaaacgc tctatacggc tcaggtaatc actttgaaaa gctcttacat
    45721 ctcgatagag tttctcaaga tgtttcccat aaatctctaa gttagtcata taagcttgtt
    45781 gttctcttct caactcattt ttaaggtatt ctttagaact atgattaaaa taagatagaa
    45841 gataaactaa aagaagtata aacatcaaaa acaataactt ataaggtgtg ggaacaaaaa
    45901 gagaatgatg aaaatgtaaa aaggggtccg taaatcctaa aatgacaaaa atgtccacat
    45961 aataaaccaa aacaaaaatc agcaatgttt gatagaaatt atgcgatcgt ttcgaatatc
    46021 cggattggca tatcatcttg taatcttttc caatcatata attaataata gcaaaacttg
    46081 gaaaaatcag cagataagca agcaagtcaa agataatatg acccagataa ataccactcg
    46141 acaaaaaaag ataggggata acgattgtac ccataaatcg agatagcaaa tccaccaaaa
    46201 cactaggtgc aacagccaaa aaaagagctt tcaaagaaaa taattgcttg gtttcttgcc
    46261 ttaaaacaac taaaaataat agaggatcaa ttagcaatgg cgacaaatac gggaactgat
    46321 tgaaaaatag ggctaaagcc aaaatcgtta gttgtttcca aactggtaat gtgatatcag
    46381 atagaaagga aaaaatataa atttttgtca tataatagac aataattgat aataataaaa
    46441 acatatattc gctattagcc atttttttct cctttccaac tttattattt tagcatattt
    46501 tatgacaatg attacaatat tatttgatta caattgatta gctaagtgag tactaaacta
    46561 gtctctttca gtatatacca aaaaaatatt gtacactaat tgattcataa aaaccatttc
    46621 tttaaatcac actaatcaaa acctcaccgt ttgctgtcat tatcacgtaa gcatctcacc
    46681 acctctcttt caaatccaat ctccaaaata gaaataaact atactatttt ttactttacc
    46741 aaggtagcaa gctcagataa cgataaaaaa gactgaagaa cttaatcttc aatctttcgt
    46801 tgtcgtgact ttttaactcc ttaaagcgtt taaaaataaa ggtgaacgat acagccttat
    46861 agcatgtttt tgatgtgctc aatggattta tcacgtccca ataaataaat cgtatttggt
    46921 aattctgggc catgcatttc accagatact gcaatacgaa taggcataaa gaggtttttc
    46981 cctttgattc ctgtttcttt ttgaacagcc ttaatttgtg ggaaaatatt ttctggtttg
    47041 aagtcttcat ctgacatagc ttccaactta gccttgaaag cttgcaagac tgtcgaaact
    47101 gtttcacctg ctatcacttc tttttcggct tctgttaatt cagggaaatc agaaaagaaa
    47161 aggtcagtca atggaataat ctcatctgca gattttaatt gaggtttgta taattctact
    47221 agcttctcag ctttttctgt caaacggcct gcctcttcaa ggaatggttt gcagagggca
    47281 taaactgttt caaaatccgc atgtttaaga tactcattgc tcatccaatc cattttcttc
    47341 tggtcaaagg cagctggcga cttgctaagg cgattttcat caaaaagggc aatcagttgc
    47401 tcacgagaga agatttcctc ttctccgcca ggattccagc caagaagggc gatgaagtta
    47461 aagacagctt caggcatata accttttttg cggtaatctt caatgaattg gagggtattg
    47521 gtgtcgcgtt ttgataattt tttacccgtt tcagaattga tgataagagt catatgacca
    47581 aactctggcg cttcccagcc aagagcttca tagaccatca attgttttgg cgtattggca
    47641 atatggtcat cgccacggat aacgtgagaa atttgcatat catgatcatc aacaacaacg
    47701 gcaaagttat aagttggata gccatctttc ttttgaataa cccagtcacc accgatgtta
    47761 ccaccttcaa actcgatatc gcctttaacc atgtcagtcc atttgtaaat accggactca
    47821 ttaacagcaa gacggactgt tggaacgata cctgctgctt cacgctcagc aatgtactta
    47881 gctttttcgt cagctgacat accaataaat tcattgatat agcgaggcgt ttcgccagct
    47941 gcttcttggc gttcacgctc tgctgccaat tcttcctcag tcacgtaaga cttgtaggct
    48001 tttccttcag ctaacaattg atcaatatat tgttgataaa gtgctagacg ttcagactgg
    48061 cggtaatttt catgcgtttc tgggctttca tcccaatcca ttcctaacca ttttaggttt
    48121 tcaagttgag aacgttcacc atcttcaaca tgacgtttac ggtcagtatc ttcaatacga
    48181 atgataaaag tacctccgtg acgacgggca taaaggtaat taaatagggc tgtgcgggca
    48241 ttcccgatat gtaaaagccc tgttggactt ggtgcataac gcacacgaat tggtttagac
    48301 atgcttcttc tcctgttaca tatatcactc agaaacctgt ggcacgaaaa acaagcaaca
    48361 aatgatgatt tgagcttgcc aagacctttt cagacttctt ctaaaatctt tcttattata
    48421 gcatatttta cttgcttagg cgaaaaaaat cagccctaaa aagctgattt tatgttattt
    48481 tgactaattt gaactagttg gtagataacg tttaagagtc ccagcaaatt gctcaaggtt
    48541 aagactttgg atataaatct caccatgacc tctaaaggta ttaacaactc cttcacctgt
    48601 accaattgac tgcataaagc cattttctaa atgaatatca taatcaagtt ctctgctcca
    48661 tgctacaaca tgggcattat caatagtcat tgtgccacca tcaagtgtga ttttcttgat
    48721 agatccaaac gagttagcaa gtaaggtacc aaggccttca gttgtcatga caaaaagtcc
    48781 gccttgacca ccaaaaagtg cttttccaat attttgacgt tccattttgt actgtgctga
    48841 accatctagg gctagaaagg caccatcatt tagacgatat tgtttttcac ctagttctaa
    48901 agcaacaatc tgtcctggtg tattgggtgc taatgctaat ttaccatctc catttgacat
    48961 agcttgtgta atgaacattg attcaccaga aaccatggaa cggccgatgg ctccaactaa
    49021 ttttcctaaa ccagatccct taccattcaa tttggtattc aaggttacat tctcagtatg
    49081 ataaaccata cttccttgtt gtaagtaaac tgatccccca tgttccagat caatctcaac
    49141 tagtggaaat tgcatgtttt gatcaatcgt aaatctcatt ctattgtcga ccatcttact
    49201 ctccttgttt gtatgaataa cttgatacaa ttattataac gcttccctat ttctttgtct
    49261 aatattttca ataattttta aaaataaaaa agagctgaat tcagctctac aacttggcta
    49321 ctaactattc cattacttgt gtcatctttc cagtatccac atcgtagacg gcaccgttaa
    49381 taacgacatc atcagagata agagaggagg ctcttatctt agccatatcc tcgcggacac
    49441 tgtcttccac atcttggaag ggaaggaaat cttgccctga aacatccaca cctaagtgct
    49501 catgaatatg cttggcaaag ccttcattag taaaagtctg cgcgccacaa tctgtatggt
    49561 ggagaaccac aatctctctc gttcccattt gctgctgaga aataaccagc gaccgaatca
    49621 tgtcttcggt gacacgtccg ccagcattcc ttaaaatatg agcatctcct agagccagcc
    49681 ccagagcttg ggccacatgt agccgtgaat ccatacaagt cacaatcgct actttagtct
    49741 tgggttttaa gggcaaatga gctgtcccat gcaaggccac ataagcctga ttggcagcca
    49801 taaaatgttc aaaataagac atcaataaac tccttttgag aaacagcaga gctatttttg
    49861 ctgttagttt gtcttatctt aacatctttt atggaaaata gctggattaa cctcttagac
    49921 ggtcggtatc gttcgaaaag ttaaaaaaac aaatgattgg gatactttct tgacaaattt
    49981 cctcctcatt tgctcttagt ttctgatcct ctagctaaaa actgcattta aaacctgacc
    50041 aaccgtagtc actccgacaa cctcaatacc ttgagggata tcaatgcctt gcaaggcatt
    50101 tttaggagca tagaccttgg taaagccaag ctttgctgct tcattaatcc gttgctcaat
    50161 acgggtcact cgccgaatct cacctgttaa cccgatctcg cctaagaaag cttcttgagg
    50221 gctggttggt ttttccttat aactggatgc gatagccaca gcgactgcca aatcaatggc
    50281 aggttcgtct agtttgacac caccagccga cttgaggtag gcatcttgat tttgtaagag
    50341 taaaccacag cgcttttcta aaactgccat tattaggctt acgcgattga aatcaagtcc
    50401 cgtagtggtt cgtctggcat tgccaaaaac ggttggtgtc actaaagatt gcacctctgc
    50461 taagatagga cgacttcctt ccatcgttac aacgacagcc gatcctgttg ccccatctaa
    50521 gcgttcctct aaaaagactt gactaggatt taagacctct accaagccgc cagactgcat
    50581 ttcaaaaatg ccaatctcgt tagtggagcc aaagcggttt ttcacagccc gcagaatgcg
    50641 aaaggtgtga tgcctttccc cttcaaagta gagaacggta tccaccatat gttctaacat
    50701 acgaggccca gccaaggttc cttccttggt gacatgaccc acaataaagg ttgcaatgtt
    50761 gttcgtcttt gcaagctgca tcaattctgc agtgacttct ctcacctgac tgactgatcc
    50821 ttgaacacct gtaatatcag ggctcatgat ggtctgaatg gagtcaataa ttaaaaaatc
    50881 tggtttaata ttttcaattt ctgtgcgaat agcttgcata ttggtttcgg catagaggta
    50941 aaattcattg tcaatatcac ccagacgctc actccgcagt ttaatctgct ctgctgattc
    51001 ttccccagac acatagagaa ccgttccctt attagcgagc tgcgtggata cctgcaagag
    51061 taaggtggat tttccaatac ctggatcacc accaattaaa atcaagcttc caggaaccac
    51121 accccctcca agaactctat taaattcaga catgtcagtc tgtgttctgt gataactaat
    51181 attatccaca tcttttagtt taaccggtct ggacttttct ccagctagac taacacgggc
    51241 atttttgact tctttgacct ctacttcttc cacaaaagaa gaccaggccg agcaatttgg
    51301 acagcgccct aaatactttg gcgactggta gccacactcc tgacagataa aggttgcttt
    51361 tttctttgcc atagtaatct ccctccccta tacaagacaa acccactctt aaagaatagg
    51421 tctgctgtca taagcatttt tgttaaatcg ctttactgcc ctgtcgaacc aaaaccacct
    51481 gttcgttcac ctctggcttg gtcaccatca gcaattaaaa aaggcataaa aacaccctga
    51541 acgatcctct cacccacagc taatgtcaca gggtgatctg taatgttttg catttgtgca
    51601 aaaatatgtc cttcattagc ctcattacca taataatctg catcaatcac acctactgaa
    51661 ttaatcagga taatcccttt ttttcgtgga tttgacgaac gatcatagag gtaaagcacc
    51721 tcgccatctt gcatataggc cttaacccct gttggtacca acttaatctc ccctggggca
    51781 atggttacag cctcagcaac agacaggtca taaccagctg catgagtcgt ctcacgtttt
    51841 ggtagtaaat caggattagt aaagcttgaa acaagctcga aaccacgaat ttttgtcatt
    51901 atgataggta tatcctttca agtcaatcat atcctcttat tatagactat tcgtaaaaga
    51961 atagcaaaaa agcggtcaac tttaaacgga ccacttttaa tcatgccatc acatctcatc
    52021 cccacgataa ctaaagcgga tgtgggtgaa atcattatcc aaatccttgt ctgccataaa
    52081 agctttggca tcttttttca cttgaaccaa gtcaatacct tgcattttgg cagcatagac
    52141 acagccacaa tagcattggc ggtaaatatc atactcctca cacatttcaa cggatctgcg
    52201 ataaccgttg tttttcttga aatcacttgg caggtatttg gtggtgtaaa ccttttgcac
    52261 atcgatgccc acatcattaa tggtttgcga atttttatga ggactgatgg ttagggcact
    52321 ggcaaagtag tcaaaaccaa gttccactgc tttttgagcg gtcttgtcta gtcggtaatc
    52381 aaaacagaca cggcaacggt ccccaccttc tggttcctct tctaagcctc gcacttgtcg
    52441 aacgtactca ttggggacat agtccgcttc gagaaactga acagtattgc ctgttttagc
    52501 gttgaactcg gagacaaact gttgtgtcac ataagctctg cgatggtatt cgtccttagg
    52561 gtgaatatta gaattggcaa agtaaaccgt aatgtcagca aactgcgtca ggtattctag
    52621 ggtgtaagtg gagcatgggg cgcagcagac atgcattaaa atactggggc gcacggattc
    52681 cttctcccaa accttggcca tctgttgcat gaccctgtca taatttatct tttgattggg
    52741 attcatgtta gcgagaatct cttgtaaatc aatcattgtg gctactttct aattgttttt
    52801 tctcttgctt gctattatac catatcagaa aagaaagctt gactgcttta ttgttcacca
    52861 aaaaactccg ctaagacgcg gagctgatgc catctattca aagacaaatt gattgtgata
    52921 caattcggca taaaagcctt tttgatgcaa tagctcatga tgatttcctt gctcaatgac
    52981 cttgccatct ttcaacacaa taatgtgatc ggcatttaaa atggttttga ggcggtgagc
    53041 aatgacaaag ctagttcgac ctgccacgat agcttccatg gcccgttgaa ttttactttc
    53101 ggtaaccgta tcaacatttg aagtggcctc atccaaaatc aacacttcag ggtcagtcag
    53161 tagcgtccta gcaatagaaa tcaactgctt ttgacctgtt gaaaagacat tgtcatcatc
    53221 tgagacatag gtattgtacc cttttggtaa ggacatgata aagtcatgaa tatgggtcgc
    53281 acgcgcagca gtttcaacca tgtcttgact aatggtctga tcaccaaaac gaatattatc
    53341 cgtaatggtt cctgaaaaaa gaactgactc ttgcaacaca atccctacct tttgacgaag
    53401 actatccaaa tcgtagtcac gaatatcacg gccatcaaag gtaatcgaac ctgcatccac
    53461 atcgtagaaa cggttaatca agttcataat agtggtcttt ccagaacctg tcggtccaac
    53521 cacggcaatc attttgccct tgggtgcaac gattgacaca tctgataaaa ctttttgccc
    53581 aggaagatac ccaaaatcga cgtggttaat cgccactgct tcttttaagc tggtgaacgc
    53641 tggtgcattt tgtggacgaa cttcttcggt ttcatcaaac atttcttgaa tacggtgagc
    53701 accggtaaag gccagctgca attctcccca actagacgcg atttgcatca tgggttggta
    53761 atattgctgg gaatattgta caaaagtaac cactaaacca agcgctgccg ctgctggcat
    53821 agatttgtca ctgaggacaa ttgttgaacc gacaaaaatc acgatagccg tgttaataag
    53881 gctcattcca ttcatgactg gaaataattg tcctgagaac agacggcgtt tgaaggtggc
    53941 ttgtcgaacc ctttcattat gctttaaaaa ggctgtcatc gtatcttctt ggacaccttg
    54001 tacaataata gccttttgtc ctgaaatggt ttcatccata aaagcattta aagcactgac
    54061 ttcttgctgt tggatattgg tgtattttct tgccaaacgg atgttaatca ctaaaaaaat
    54121 gagagcaact ggggttgatg cgatggttaa caaagctaaa cggctatctt gcctaaacat
    54181 catccagacc aggccgatgt aaagggcaat attagtcacc acttgaatca aggattggtt
    54241 cagcgagttt tgaatattat ccaaatcact cgtgaaacga gaaagaatct ccccatcttt
    54301 atggcggtca aaaaaggcga cggttaaacg ttctaattta ccaaataagc ccttgcgcat
    54361 gcggttagtc gaatgtgaga caacacgtgt aagtaagaaa ctatatatta gattagctaa
    54421 aacagtaaag aaataagtca tcaaaagctt aaacatcacg gcattaaaag ctgataaatc
    54481 agggctaaaa tgtgtctggc cactcatctt agcaacgtaa taagcctgac cgatttttcc
    54541 caactcagtc aaggactctc ctaagaagac aggagctttt acttgtaaat aagttgctaa
    54601 gataacggca acagcaatga cagtaaatga gaaacgatag cgtttaaaat aaaaccagaa
    54661 aaaacgtgct gttttcatca ctactcctcc cttccttttt gtgtctcata aatttcacga
    54721 taaatcgcat tattagccac caactctgcg tgtgttcctt ctccaattaa ctgtccttgg
    54781 tcaaggacta agatcttatc tgccttaact accgatgaaa ttttttgagc aacaataact
    54841 gtagttgtac cttctaattt atgacttaag gcttcttgaa cgcgtttttc agattttgca
    54901 tcaagagctg aagtggaatc gtctaatata agaattttgg gatgattaat gacaccacgt
    54961 gcaatagaca gacgttgctt ttgtccgcca gacaagttac tacctcgctc ttcaacttgg
    55021 ctctcataac ggctatccat acgatcaata aattcttttg cttgcgcgat ttgagcggct
    55081 ttttgcatag catcaatatc agcttttgct gagccttggc gaaggttatc agctatcgtt
    55141 cctgaaaaga gaatagcctt ttgcaacacg atggaaaccg attggcgcag ggttgtttga
    55201 cttagggttt taatcggctt tcctcctaac aaaatttggc catcttgagg atcaaataag
    55261 cgagggatga gctgtgcaag cgttgatttc ccagatcctg ttgcaccaac gatgccgacc
    55321 atttgcccag gttcaatagc aaaagaaatg tgcttcaagg ttggctcatc atcattagga
    55381 tatgtaaaac taacatcgtc aaatacaatg cttcctgaga tggtttcttc cttttcattt
    55441 tcaaatgtca tggcaggttc tgtagacaat atttgcctaa ttctagccat agaaacaaaa
    55501 gcacgactaa cttgcatccc catggaacca accacaataa ttgaaaacat aatttgcatc
    55561 atataagtca tgaaagaggc aatattccca atcactgttg gatctgtttc gaccatggtc
    55621 gaaacaacat ttatagaaac ataaactgcc aaataagaca ccaacattaa agccggctgc
    55681 attagtgaaa aaccataacc aatagataaa tttaacgcca aaagatcatt ggacgtttct
    55741 ttaaatttag tgtattgttg ttgttcttgt acaaatgatt taaccacgcg aacgccacgg
    55801 agattttcct tagcgatgcg attaatctta tccattaacc gttgaaattt accaaaacga
    55861 ggacccattt gacgcatcac caaacccatg atgagggcaa ttaagataac cattacaaca
    55921 atgacccacc ataattgagg gaatgtctga actgccataa taaacgcgcc aataaaaagg
    55981 atcggcaaac gaaagagaat ttgaaacatc atcatgacta aactttggat ttgattgata
    56041 tcattagtta gcctaaccac aagattacca gcattaaaag cttcaatatt ggcatatgaa
    56101 aagtcttgga tttttcgaaa ggtcttctcc ctcatatcag cagatacacc ttgagctatt
    56161 ttagcagcta aaaccgtatt aatcgctcca gacattaacc ctaaaagggc aataataagt
    56221 aatggtttcc caacctcata aattttctct tgattatttt gaataacagc gcttagcaca
    56281 gatttaagat aatgtggttg caagagacta cttgcaacaa ccccaataac cataaaaaat
    56341 gagcctaaag cataccattt ataacgtaag attgcgtctt taagcatcgt tgtctccttt
    56401 ataagttagc atattttgct tgagctgttc aattactttt ttcgctgtca gcaactcttc
    56461 ttttgtaatt tcttttaaaa aatagtgctc gatatcctta cgacactccc gcaacaaagg
    56521 caatttatct ctaccaacct gcgctaacac tacttgctta taacgcttat ccacttggga
    56581 aggcatcaca ttgataaacc catttttgac catacgtttc actaaatgac tagcaactga
    56641 ctttgagata cgaagttgtt tttcaatatc tttgacaaat atttcttgat tttggtgttt
    56701 agctaaaaaa acaagaacat aaccttgagg acctgctaga tgctctacat catatttttt
    56761 tgcaatctca tcactaattt gttcgatttg atgtatcaat tcacgtaaat cacctatcac
    56821 ttgtgacatc tcttccctcc ttattttctt taatagtttc tatgataagt attttagttc
    56881 tctagataac tattgtcaat taaaatatct ttatttttaa aaataagttt ccgaacttaa
    56941 ataactaaaa agaacagggc aaagccatga caacagctca cctgatgaag cttattaaac
    57001 aacattatta atatagctag ctctcttggg aacgccttat tagccaagac catatacctt
    57061 ttctaataga gctaatcaag gtgttatgtt ataatagagt gactagctct tgaaggagaa
    57121 tttagaatga caaaacaaaa agtagctatt ttaggacctg gttcttgggg aactgccctt
    57181 tctcaggttc ttaatgacaa tggccatgac gtccgtttat ggggaaatat tcctgatcaa
    57241 attgaagaga taaataccaa gcataccaat agacactact tcaaagacat tgtgttagac
    57301 aaaaacatta cggcaactct tgatttaggt caagccctat cagatgttga tgcggtgctt
    57361 tttgttgtgc caactaaagt aacacgatta gttgctagac aagttgccgc cattttagat
    57421 cataaagtag tggtcatgca tgcctcaaaa ggtctagaac cagagaccca cgaacgttta
    57481 tcaactatcc tagaagaaga aattccagct cattttcgta gtgaagtggt cgttgtatca
    57541 ggtcctagtc atgctgaaga aactatcgtt cgcgatatta ctctcatcac ggcagcctca
    57601 aaagatattg aagctgcaaa gtatgttcag tccctcttta gtaaccacta cttccgactt
    57661 tataccaata ccgacgtcat cggagttgaa acagctggtg ccctcaaaaa cattattgct
    57721 gttggagcag gagctctcca tggacttggg tatggagata atgccaaagc agcggtaatt
    57781 actcgtgggt tagctgaaat cacccgtcta ggcgtcaagc ttggtgctga cccgttaacc
    57841 tacagtgggt tatctggtgt tggtgatcta attgtaacag gtacttctgt ccattcacgt
    57901 aactggcggg ctggagctgc ccttggacgt ggtgaaaaat tagaagatat tgaacgcaac
    57961 atgggtatgg ttatcgaagg tatcgcaaca actaaggtag cctatgaaat tgcccaagac
    58021 ctcggagttt acatgccaat tacaacagct atttataagt ccatctacga gggcgctgat
    58081 atcaaagaaa gcatcctcgg catgatgtca aatgaatttc gttctgaaaa tgaatggcat
    58141 taagccatgc gtcactaaaa taagaggagg tgctgatgac caaagtcaga aaagctatta
    58201 ttcccgcagc aggtttaggc acacgttttt tacctgcaac caaggccctt gccaaggaga
    58261 tgctacctat tgttgataaa ccaactattc aatttatcgt tgaagaagct ctaaaatcag
    58321 gtatcgaaga aattcttatc gttactggaa aatccaaacg ctccatagaa gatcattttg
    58381 attctaattt tgaattagaa tataatttac aggctaaagg aaaaatcgaa cttctaaagt
    58441 tagtagacga gaccacttct attaatcttc actttattcg acagagtcat ccaagaggat
    58501 taggagacgc agttcttcaa gcaaagacct ttgttggcaa tgaacctttt gttgtcatgc
    58561 taggtgatga tctgatggat attacaaatc caaatgtaaa accattaacc aaacaattga
    58621 tcgatgacta tgaagaaact catgctgcaa ctattgccgt catgagggtt cctcacgagg
    58681 atgtctctaa ctacggtatc attgctcctc aagcaaaagc agtaaaagga ctctatagtg
    58741 tggatacttt tgttgaaaaa ccacaacctc aagatgcacc tagtgatttg gcaattattg
    58801 gacgttactt gctcacacca gaaattttta gtattttaga aaaacaagaa cctggtgcag
    58861 gcaatgaagt tcaactgact gatgctattg ataccctcaa taagacacag cgtgtctttg
    58921 ctcgtgagtt taaagggaaa cgctatgatg ttggcgataa atttgggttt atgaaaactt
    58981 ctttggatta tgccctgaaa caccctcaag tcaaagatga cttgaaagcc tacatcatcc
    59041 aactgggcaa agcactagag aagacaaaac cataaaaata aggagggaaa atccctcctt
    59101 atttttatgg tttttaagtc atttcatcct actagccatc tgagaagtaa cagtgctaac
    59161 cactcactta tttttataaa aacccaagca ctaacacacc aaccaaaata ataccatagc
    59221 tcactaaagc caacattcgc ttggttttct tcactgttat cactctcatc ttagttggaa
    59281 aaactatact cagtaacgca ccacccacga caccgccaat atggcctgcc atactcacgt
    59341 ttggcataaa aagattcatc agtaaattga ctacaattaa cgtctggtat gacttgccca
    59401 aatctttcaa cgcttggttc ttacccaaaa aactcaatac tacaatagca gcaaaaagtc
    59461 caaataacga cgtcgatgct cctgcagcta ctgtttcagg agtcaaccaa aaagtaaagg
    59521 cattgcccat aacacctgat aaaacataaa gtaataaaaa acggcgtgag ccccagaggt
    59581 cttcgacgat ttgaccaaca aaatatagtg ttaatccatt gacaaaaaaa tgaccaaagc
    59641 cgatatgaat aaatatcgga gtcaccaatc gccacaactg gtctggcatt gcttttacta
    59701 gtaatccaaa catacctcca acttgataaa tagcttgagc accagttgct aaatgtccat
    59761 ataccacttg cattgctata aaaattaagc ctgttaaccc taaaaggaaa atagtaatag
    59821 gatatcgttt taataactgt gtcatctaag ataaacctcc taaacagcaa tatcataaat
    59881 cgtttgattt ggcaatcgta ttggcccgct gataagcttg attgctaaca acatccacta
    59941 ataaagcttg atcattttga cgttttaagt ctacatccat agttcgtaaa gactagaaga
    60001 gttctttgag aatctctttt ttcatcatct tcttatcata ccataaatta ggaaaaaggt
    60061 tcaaggctga caagaaacta
//
LOCUS       DAUGJR010000005        58231 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUGJR010000005 DAUGJR010000000
VERSION     DAUGJR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58231
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.005"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(21..359)
                     /gene="cadX"
                     /locus_tag="VH800_000304"
     CDS             complement(21..359)
                     /gene="cadX"
                     /locus_tag="VH800_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEQ8361402.1"
                     /translation="MKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(371..985)
                     /locus_tag="VH800_000305"
     CDS             complement(371..985)
                     /locus_tag="VH800_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEQ8361403.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLSK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFIAVVYLGLGMYILIENNSFDMLWAVLG"
     gene            complement(1278..1427)
                     /gene="rpmG"
                     /locus_tag="VH800_000306"
     CDS             complement(1278..1427)
                     /gene="rpmG"
                     /locus_tag="VH800_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8361404.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(1443..1625)
                     /gene="rpmF"
                     /locus_tag="VH800_000307"
     CDS             complement(1443..1625)
                     /gene="rpmF"
                     /locus_tag="VH800_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEQ8361405.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            1845..3125
                     /locus_tag="VH800_000308"
     CDS             1845..3125
                     /locus_tag="VH800_000308"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEQ8361406.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYSHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDIYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            3463..5211
                     /gene="aspS"
                     /locus_tag="VH800_000309"
     CDS             3463..5211
                     /gene="aspS"
                     /locus_tag="VH800_000309"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEQ8361407.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSNVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGNDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            5204..6145
                     /locus_tag="VH800_000310"
     CDS             5204..6145
                     /locus_tag="VH800_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8361408.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            6165..7043
                     /locus_tag="VH800_000311"
     CDS             6165..7043
                     /locus_tag="VH800_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8361409.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            7086..7958
                     /locus_tag="VH800_000312"
     CDS             7086..7958
                     /locus_tag="VH800_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8361410.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(7985..8293)
                     /locus_tag="VH800_000313"
     CDS             complement(7985..8293)
                     /locus_tag="VH800_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8361411.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(8381..10072)
                     /locus_tag="VH800_000314"
     CDS             complement(8381..10072)
                     /locus_tag="VH800_000314"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEQ8361412.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            10363..10800
                     /gene="argR"
                     /locus_tag="VH800_000315"
     CDS             10363..10800
                     /gene="argR"
                     /locus_tag="VH800_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8361413.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            10797..11149
                     /locus_tag="VH800_000316"
                     /pseudo
     CDS             10797..11149
                     /locus_tag="VH800_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623648.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            11136..13691
                     /gene="mutS"
                     /locus_tag="VH800_000317"
     CDS             11136..13691
                     /gene="mutS"
                     /locus_tag="VH800_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEQ8361414.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTNLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPS
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEVIDVMNMTPLQAMTTLYELKKLL"
     gene            13820..15802
                     /gene="mutL"
                     /locus_tag="VH800_000318"
     CDS             13820..15802
                     /gene="mutL"
                     /locus_tag="VH800_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEQ8361415.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKVELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLE
                     NEGQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            15813..17033
                     /locus_tag="VH800_000319"
     CDS             15813..17033
                     /locus_tag="VH800_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8361416.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYCFDETRPETHAFDHGKGLLASFQNYRQVFHDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLSFTFTQFYAIWLSVVLLTFGEMINVS
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFAVIALL
                     GIYFTVVSAKMKKV"
     gene            17035..17631
                     /gene="ruvA"
                     /locus_tag="VH800_000320"
     CDS             17035..17631
                     /gene="ruvA"
                     /locus_tag="VH800_000320"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEQ8361417.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
                     LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            17641..18201
                     /locus_tag="VH800_000321"
     CDS             17641..18201
                     /locus_tag="VH800_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEQ8361418.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLDDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVATFTSEEMADALENPSIIRHKLKLAATVNNAIA
                     VQKIQKEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            18270..19541
                     /locus_tag="VH800_000322"
     CDS             18270..19541
                     /locus_tag="VH800_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEQ8361419.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            19630..20766
                     /gene="recA"
                     /locus_tag="VH800_000323"
     CDS             19630..20766
                     /gene="recA"
                     /locus_tag="VH800_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEQ8361420.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDLKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            21057..21455
                     /gene="spx"
                     /locus_tag="VH800_000324"
     CDS             21057..21455
                     /gene="spx"
                     /locus_tag="VH800_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEQ8361421.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            21568..21837
                     /locus_tag="VH800_000325"
     CDS             21568..21837
                     /locus_tag="VH800_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEQ8361422.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            21834..22253
                     /gene="ruvX"
                     /locus_tag="VH800_000326"
     CDS             21834..22253
                     /gene="ruvX"
                     /locus_tag="VH800_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEQ8361423.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AKRMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            22265..22570
                     /locus_tag="VH800_000327"
     CDS             22265..22570
                     /locus_tag="VH800_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEQ8361424.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            22983..24542
                     /locus_tag="VH800_000328"
     CDS             22983..24542
                     /locus_tag="VH800_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEQ8361425.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSAAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKESHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            24639..26837
                     /gene="nrdD"
                     /locus_tag="VH800_000329"
     CDS             24639..26837
                     /gene="nrdD"
                     /locus_tag="VH800_000329"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEQ8361426.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEHEIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            27019..27165
                     /locus_tag="VH800_000330"
     CDS             27019..27165
                     /locus_tag="VH800_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361427.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            27194..28129
                     /locus_tag="VH800_000331"
     CDS             27194..28129
                     /locus_tag="VH800_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8361428.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTNLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            28138..28647
                     /locus_tag="VH800_000332"
     CDS             28138..28647
                     /locus_tag="VH800_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8361429.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSYAISKNITTILVTCDETNIASRAVIVANGGILEDSRGGTERY
                     WIEEQRGDK"
     gene            28647..29261
                     /gene="nrdG"
                     /locus_tag="VH800_000333"
     CDS             28647..29261
                     /gene="nrdG"
                     /locus_tag="VH800_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEQ8361430.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(29435..30166)
                     /gene="yaaA"
                     /locus_tag="VH800_000334"
     CDS             complement(29435..30166)
                     /gene="yaaA"
                     /locus_tag="VH800_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEQ8361431.1"
                     /translation="MLTFLIPTAKEMTIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEESAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(30208..31065)
                     /locus_tag="VH800_000335"
     CDS             complement(30208..31065)
                     /locus_tag="VH800_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8361432.1"
                     /translation="MIYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPGDKAYGLYHTAFLVPDRHSLGLVLNHFLTRSISLEGAAD
                     HGHSEAIYLSDPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKH
                     FLLAQDTRIRHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYYHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     RVNVILGQD"
     gene            31324..31590
                     /locus_tag="VH800_000336"
     CDS             31324..31590
                     /locus_tag="VH800_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361433.1"
                     /translation="MLRDLLKGTLRFGQLKSSIGSVSQKVLTAQLRAMEADGLVHREV
                     YAEVPPRVEYSLTETGLSLAPVIEAMSDWGQTYQEKHADLFEEG"
     gene            complement(31869..32582)
                     /gene="treR"
                     /locus_tag="VH800_000337"
     CDS             complement(31869..32582)
                     /gene="treR"
                     /locus_tag="VH800_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEQ8361434.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            32793..34817
                     /gene="treP"
                     /locus_tag="VH800_000338"
     CDS             32793..34817
                     /gene="treP"
                     /locus_tag="VH800_000338"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEQ8361435.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKVVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSSIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSD
                     APVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDVFTVTVEGSLPRQIKVNDKLAVAVKK"
     gene            34884..36512
                     /gene="treC"
                     /locus_tag="VH800_000339"
     CDS             34884..36512
                     /gene="treC"
                     /locus_tag="VH800_000339"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEQ8361436.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLLGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFENLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILADN"
     gene            36720..38615
                     /gene="pepO"
                     /locus_tag="VH800_000340"
     CDS             36720..38615
                     /gene="pepO"
                     /locus_tag="VH800_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEQ8361437.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(38781..39821)
                     /locus_tag="VH800_000341"
     CDS             complement(38781..39821)
                     /locus_tag="VH800_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEQ8361438.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKADEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(39955..40722)
                     /gene="rpsB"
                     /locus_tag="VH800_000342"
     CDS             complement(39955..40722)
                     /gene="rpsB"
                     /locus_tag="VH800_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEQ8361439.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            41026..44100
                     /locus_tag="VH800_000343"
     CDS             41026..44100
                     /locus_tag="VH800_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8361440.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLVYINSQLGSQPVTAEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSASIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(44131..45117)
                     /locus_tag="VH800_000344"
     CDS             complement(44131..45117)
                     /locus_tag="VH800_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEQ8361441.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS"
     gene            complement(45303..46844)
                     /gene="hutH"
                     /locus_tag="VH800_000345"
     CDS             complement(45303..46844)
                     /gene="hutH"
                     /locus_tag="VH800_000345"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEQ8361442.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACHIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAVGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(46855..48198)
                     /locus_tag="VH800_000346"
     CDS             complement(46855..48198)
                     /locus_tag="VH800_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEQ8361443.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFESLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(48418..49014)
                     /locus_tag="VH800_000347"
     CDS             complement(48418..49014)
                     /locus_tag="VH800_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEQ8361444.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     TATVALRQTTFTRLDGYHRILMSLDKPITLSDLSHAKEISLAPFQPYAFEGDTRIVSR
                     GTCQDINLMYDDQYQGQLLPVWSDTPFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVTEQEASLSDLKVCLNQTSPAQTPVAVWAGLWYKT"
     gene            complement(49036..50709)
                     /locus_tag="VH800_000348"
     CDS             complement(49036..50709)
                     /locus_tag="VH800_000348"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8361445.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDAR
                     QLVALKNKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGIPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLT
                     KIVTKVYGGKGINLSSAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(50727..51353)
                     /locus_tag="VH800_000349"
     CDS             complement(50727..51353)
                     /locus_tag="VH800_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formiminotetrahydrofolate cyclodeaminase"
                     /protein_id="HEQ8361446.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQDIITEIHAKSTALQASLLAAIDKDTEAFNLVSAVFDMPKETDEDKA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(51364..52263)
                     /gene="ftcD"
                     /locus_tag="VH800_000350"
     CDS             complement(51364..52263)
                     /gene="ftcD"
                     /locus_tag="VH800_000350"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEQ8361447.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYHKQILENHLLG"
     gene            complement(52352..54382)
                     /locus_tag="VH800_000351"
     CDS             complement(52352..54382)
                     /locus_tag="VH800_000351"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEQ8361448.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFEEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRFRPKDRIYGKPIDEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIKTRHSQGWISQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGNHDDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            54674..55939
                     /locus_tag="VH800_000352"
     CDS             54674..55939
                     /locus_tag="VH800_000352"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEQ8361449.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGTQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(55997..57529)
                     /gene="ahpF"
                     /locus_tag="VH800_000353"
     CDS             complement(55997..57529)
                     /gene="ahpF"
                     /locus_tag="VH800_000353"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEQ8361450.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHGSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(57550..58110)
                     /gene="ahpC"
                     /locus_tag="VH800_000354"
     CDS             complement(57550..58110)
                     /gene="ahpC"
                     /locus_tag="VH800_000354"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEQ8361451.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
BASE COUNT        17057 a        10637 c        12790 g        17747 t
ORIGIN      
        1 gaaagtagta aaaatagttg ttatcctagt tgattaaaaa aatctctgat ttcctcatct
       61 tttataaaat aatatataat tttcccctct cttctagtgt ccaagatgtt ttgattggct
      121 agtttacgaa gatggtggga ggcagatgcc atactgagat ttaataaaca ggctatatcg
      181 cagacacaga gttcttcgac ggcaaggaga taaaagatga tatttatctg tttattatcg
      241 gtaaattttg ataaaatacg aagtgatttt tggacttttt ccttttcaag gtagttcgtt
      301 gcggttgtaa cattttgttg atttataaca cccacttgac agatactatc ttttttcata
      361 attttttctc ctagcctaac acagcccata gcatgtcaaa gctgttgttt tcaatcagga
      421 tatacatccc caatcctaaa taaacaacgg caataaacca tctgctatat ttttccaaag
      481 tttctccaac agaagggact tgtgccaatt tttgggcaga aaaaaccaag agataaatca
      541 tgactagaaa ggtaagtaaa gccactatca aattcgctaa atttaaggta gtaaaatatg
      601 ggacaaagac accaatattg tcagcaccac aacttgcaaa agtaatcata gcgactagaa
      661 aaatcaggtt tttattatct ttgctcaaac cttctttggc aatagcttct ccatcagaat
      721 ctcctaaaag caaaactttg aggcctagga aaattggaat caaaccgagc aaacctaaaa
      781 tctctttact aggaatataa tctaagacaa atgcaaaaag caaacttagc aatattagac
      841 taacagagcc tagaaattgt cctaaataga tgttaatgat gtcttttctg ctttttcttt
      901 tggcaaaaaa taacattagg ataataagta agtctacggc tgtcccagaa tacaggatta
      961 ttgaagtaac aacattttga atcataaaac acctcattca aatatatttt tgaatgaatt
     1021 ttaacattaa actttgtaga tgtcaatttc agctacacca aaatatagat aagaagttag
     1081 tgtaccaaat ataaaaaagc cctgccatcc aaatgataac agggcttaac ttcaatatcc
     1141 aaatgatata ttcatctaaa aaaggtagag taaaaggtag agttcttatt gatttatatt
     1201 acaatgtaat gaacttcaaa aattcaaaaa tcgcttaaaa tcaatgtttt gacgtctaat
     1261 gacgtgtagt gaacccctta cttaacctct gtaaatgtaa cgtgtttacg taattttggt
     1321 gagtattttt tcaattgaag acggtctgga gtgttacgtt tgttttttga agtaaggtac
     1381 aagcgttcac cagattcttt atgttcaagt gtaatattta cgcgcatggt atctcccttc
     1441 tattatttag cttcgttagc tttagcgatt ttacgtcctt tgtagtatcc tttaagggat
     1501 acacggtgag aacgtgagta atctccagta gtttcgtcga attgtacaga tggagctgtc
     1561 aatttgtagt gtgtacgacg tttgtttttc ttcgcttttg acgtgtgacg tgcaggtact
     1621 gccattttct tgttcttcct ttcgatgtgt aagttttgat tttcatcaac ttcactatga
     1681 taacatatct tttttgtaaa gtaaagttac ttgacaaaac tttttatttt tacaatttca
     1741 tggtgaaaat actatcaaac taaagcaaat gatatatgct tgtttaaaat ataagaaaaa
     1801 atggtagaat gtttaaagag aaaactaatc aaagaggtaa acttatgaaa cttcaaaaac
     1861 caaaaggaac ccaggatatt ctgcctgggg atgctgcgaa atggcagtat gtggaatctg
     1921 ttgcgcgtga tacgtttagc caatataatt atggagaaat tcgtactcct atgtttgaac
     1981 actacgaggt aatctcgcgg tctgtaggtg atacgactga tattgtgacg aaggaaatgt
     2041 atgatttcta tgataaagga gatcgtcaca ttaccttgcg accagagggt acagctccag
     2101 tggtgcgttc ttatgttgaa aataaattgt ttgcgccaga ggtccaaaaa cccgtcaaac
     2161 tttattatat cggttccatg ttccgctacg aacgtcctca agctggtcgt ttacgtgaat
     2221 ttcaccagat tggggtagaa tgtttcggcg ctgctaatcc agcaacagat gttgaaacca
     2281 ttgcgatggc ctatcacctc tttgaaaaat tgggcattaa ggatgtcacc cttcatttaa
     2341 atagtttggg gagtcctgag agtcgtgcag cttatcgtca agccttgatt gactacttaa
     2401 caccaatgcg tgatcaatta tctaaagata gtcaacgtcg cttggatgaa aacccactgc
     2461 gcgtgcttga ttctaaagaa aaagaagata aactagccgt tgaaaaagcg ccttctattt
     2521 tggattactt agatgaggaa agtcaggcgc actttgaggc ggtcaaagat atgcttgaag
     2581 cacttgacat tccttatgtg attgacacca atatggtgcg tggccttgat tactatagcc
     2641 acactatttt tgaattcatc acgtctgtgg aaggttctga cttaactatc tgtgcgggtg
     2701 gacgttatga tagtttggta ggttattttg gtgggcctga gactccagga tttggctttg
     2761 gtcttggttt agaacgtctc ttgatgatta ttgaaaagca gggcattacc ttgccaattg
     2821 agacagagat ggatatttac cttgctgtgt taggtgatgg tgctaatagc aaagctttag
     2881 aattggttca agccattcgc cgtcaagggt ttacagctga acgagattac cttggccgta
     2941 agattaaggc tcagtttaaa tcagccgata cctttaaagc aaaattggta atgactttag
     3001 gagaaagtga agttgaagca ggcaaagctg tgattaagaa taatcgtagt cgtcaagaag
     3061 tggaagtcag ttttgaagat atgatgacaa actttgcgaa catctcagag caattattat
     3121 cttaatgatt ttattgtcgt cataagcttg tgttgatatg attgtttaga agataatcac
     3181 taaaacaggt gtaacttctc tttttagaag ggagttgcac ctgtttgttt tctgtaaggg
     3241 gattgattag ctttcttagt attctgtgag gacacttgat atgtcaaaat actgacggct
     3301 cagtattttt gctttatctt tagaaaaact ctttttaaat gggtggggtt tttaagggct
     3361 ttttgctata atagtaggga atgaattaat tgatttatat agtgaaagga attggaaacg
     3421 agcaggtttc acaggattct gtttgtttta gggaatttat ttatgaaacg tagcatgtat
     3481 gcagggcgtg ttcgcgaaga acacattgga acgacaatca cattgaaagg atgggtcagt
     3541 cgtcgtcgtg acttgggtgg tctcatcttt attgatttgc gtgaccgtga gggtgtgatg
     3601 caattagtca ttaaccctga ggaagtttcc agtaatgtga tggcaactgc tgaacgctta
     3661 cgtagtgaat atgtgattga agtggaaggt tttgttgaag ctcgacaaca agccaatgat
     3721 aagttggcga caggaatggt tgagttaaaa gtatctgctt tgaccatttt aaacacagct
     3781 aaaacgacgc cttttgaaat taaagatgac gttgaagtaa gtgatgacac gcgtttacgt
     3841 taccgttact tagatttacg acgtccagaa atgttagaaa acttcaagct acgtgcaaaa
     3901 gtgactcatt ctatccgtaa ttaccttgat gaccttgagt ttatcgatgt cgagacacct
     3961 atgttgacaa aatcaactcc agaaggtgcg cgtgactatc tggtaccaag tcgtgttagc
     4021 caagggcatt tctatgcttt gccacaaagt ccgcaaataa ccaaacagtt attgatgaat
     4081 gctggctttg atcgctatta tcaaattgtg aaatgtttcc gcgatgaaga tctacgtggt
     4141 gaccgtcaac ctgagtttac acaagttgac ttggaaacgt cattcctttc tgaacaagaa
     4201 attcaagaca tcgttgaagg catgattgct aaagtgatga aagagacaaa agaaatagat
     4261 gtaaccctac cattcccacg tatgagctac gatgtagcaa tgaatagcta cggctctgat
     4321 aaaccagaca cacgttttga aatgctttta caagacttga cagtaactgt caaaggaaat
     4381 gacttcaagg ttttctcaga agcaccagct gtcaaggcga ttgtggtgaa gggaaatgca
     4441 gatcgatact ctcgtaaaga tattgacaaa ttaactgagt ttgccaaaca atttggtgct
     4501 aaaggccttg cctgggttaa ggtgacagat ggtcaattgg caggcccagt agccaagttc
     4561 ttgacagcta ttgagacaga gttgtcaagc caattaaaac ttgctgagaa tgatttggtt
     4621 ttatttgtag cggatactct tgaggttgct aataatacat taggtgccct tcgtaatcgt
     4681 attgccaagg accttgacat gattgatcag tcgcagttta atttcctttg ggtggttgat
     4741 tggccaatgt ttgagtggtc agaagaagaa ggacgttata tgtcagctca tcaccccttc
     4801 actcttccaa cgccagaatc tgctcatgag ttagagggtg atttggctaa ggtacgggct
     4861 attgcttacg acatcgtttt aaatggttac gagcttggtg gtggtagcct gcgtatcaat
     4921 caaaaagaga tgcaagagcg catgttcaag gctcttggct ttaccgctga tgaagctaac
     4981 gaccaatttg gtttcttact agaagcgatg gactacggct ttcctcctca tggtggcttg
     5041 gcaattggtc ttgaccgttt tgtcatgttg cttgctggaa aagacaatat tcgagaagtt
     5101 attgccttcc ctaaaaataa caaagcctct gatccaatga cgcaagcacc tagtcttgtt
     5161 tctgaaaacc aattagaaga actcagtctt caaatagaaa gtcatgatta agaaaacaac
     5221 ctataagaaa aaagttaaat atgtcattag tagaggggcc aagaaagttg gcctactcca
     5281 cgctctaaga agtatttcaa gagaaaaata tgcagagaag atttcggctt ctctgcttta
     5341 tggcattctc tctagtattg ctgtgaattt tttcttccag cctgggcatg tttattcaag
     5401 tggagcaact ggtctagcac aggttttttc agctcttagt catcgtcttt taggctatga
     5461 ttttcccatc gcctttgcgt tttatttgat taatattcct ttgcttattt tagcttggta
     5521 taaaattggg catcaattta ccatttttac ctttatcaca gtcagcatga gttctttctt
     5581 tattcaaatc atgcctcaag tgacgctgac gactgatcct cttatcaatg ctatttttgg
     5641 tggtttggtt atgggaatgg gaattggtac aggtctcaaa tcacgtatct ctagtggggg
     5701 gactgatatt gtcagtttga cccttagaaa acgaacaggc aaggatgtgg gcagtctctc
     5761 attgatggtt aatggtgcaa ttttagcctt tgcagggatt ttatttggct ggcagtacgc
     5821 cctttattct atggtctcta tctttgtatc aagtcgtgtt acggatgcca ttttcaccaa
     5881 gcaaaagaaa atgcaggcaa ctattgttac cagccatcca gagcgtgtga ttcatatgat
     5941 ccataaacgt ctgcatcgcg gagtgaccag tatcaacgac gcagaaggga cttacaagca
     6001 tgaacaaaaa gcagttttga ttaccatttt gacatgtgaa gaatacccag aattcaaatg
     6061 gctgatgtta aaaacagacc cacaagcctt tgtttcagtg gctgagaatg ttagaattat
     6121 cggtcgtttt gtggaagatg attaagaaaa acacaggagg tgtcatgtca attgaccaac
     6181 gtttacagtt aaagaaattt tgctttatta ttttaggagc tgctatctac gcctttgctt
     6241 ttgtttattt ttacatggct aatcgcattg cagccaatgg tttagctggt ctcaccctag
     6301 ttggtaaggc actttttgag attgatcctt ctttgatagg ctatttgatt aatttgcctt
     6361 tggtcttgct gggagctaga tgttttggga aaagagccat ggtttacaca gtaacgggta
     6421 ttttatcact ttactttttt gtgtggctgt ttcaacgctt tcctttggtc gttgacttgg
     6481 accatgacaa tttagtcgtt tccttgatgg ctggaattat tggtggtcta ggtggcggtc
     6541 ttgtgtttcg caatggtgga accatcggtg gagcagatat tattgctaag ttattagaag
     6601 acaagttagg actacagctg aatcaagctc ttttaggcat tgatcttttt gtcatgattg
     6661 tctctttgac ttatatttcc ctgccgcaaa tgatgtatgc tctgattgct agctttatgt
     6721 atggtcaaat tgttcgcttg gtacaacaag gtggttattc agcccgtggc atttttatcg
     6781 tttcagaaca agcggagaaa attgcccggt tcatcatgga cgaattggga agaggagtta
     6841 cttatctaac aggtgaagga gcctactctg gtcgccgtaa aaaagtgatt tatgtggctt
     6901 tggggcgaag agatattagg gaattaaaag cttttttaac tcaggttgat cccaatgcct
     6961 ttatcactta ttttgatgtt aatgaagtca atagcccaga atttttaact attaaaagca
     7021 aataccataa aaagagaaaa taaatgagca ttagagttgc ctgcgaagaa tagtgaggat
     7081 aaaggatggc acatcacgat aaattgacta aactactaaa actgtttttg attgccctag
     7141 gtgtagccat ttataccttc ggttttgtta attttaacat ggctaatgct ttggctgaag
     7201 gtggtgtggc aggaataacc ttgattttac acgcgcattt tgggattaat cctgcttact
     7261 cttctctctt atttaatctt ccacttttta ttttaggggc aaagattttt gggaagcgtt
     7321 ctttggctct aaccatctat ggaacagttc tgatgtccgc ttttatctgg atgtggcaaa
     7381 aagttcctat cgaacttggc ttggaaaatg acatgatgtt ggtggctgta gtggcaggtc
     7441 tcttttcagg gattgggagt ggcattgttt ttcgctatgg tgcaaccaca ggtggaacgg
     7501 atattattgg tcgcattgca gaagaaaaat ttggagctaa gctaggtcaa actttgcttt
     7561 tggtggatgc tcttgtattg acagcttcgt tgacttatgt ggatttaaaa cacatgcttt
     7621 acactttggt ggcaagcttt gtttttagcc aaatgattag tgtggttcaa aatggtggtt
     7681 acactatccg tggaatgatt attattacca agcattcaga ggctgccgct caagctatcc
     7741 taaccgaaat caatcgtgga gtgacttact tgaaaggtca aggagcttac tctggtaatg
     7801 attacaatat catgtatgtg accttgaacc caactgaagt tcgggaagtc aaacgtattt
     7861 tagctggttt ggatccagat gcctttatct ccattattga tgtggacgaa gttattagct
     7921 ctgattttaa aattcgccga agaaattatg ataaataaaa atacaggtca aacagcctgt
     7981 atttttattt tggtccccca cttaagaaac taccaagcat aatagctgat atagcagttc
     8041 ccttgtaatg gctagctttt gtttttacca agcgactaag atcaaatatg cttttaggag
     8101 catcaaattg atgtgttaag atgtattgat tgataagtga gtcaattttt gtagctagga
     8161 gtgagctcat cccctctttt tcaagttgac tggcgagctc gaagatcgct tgacgaaaat
     8221 aatcatctgc ttgtattact tgttcgctat aaactttact aagagcatct aatatttctt
     8281 tttctgatgg catggcattc tcctgtaaca tattgtgcta ttattataat ataaaaaact
     8341 aagactgtca taaatgtgac agccttagta atgttattac ttacatttca tttggtgcgt
     8401 caacaccgag taagcgaagc gcttctttaa gaacagtagc agttgcatag cagagagcta
     8461 agcggttatc acgttctgag ttgtcgtcga gaatgcgagt gtgagcataa tatttgttaa
     8521 agctttgggc taagttaata gcaaatttag ccataataga aggctcaaag ttatctgatg
     8581 ttcgcttgat aatgcgtggg aaatcttgga taagtttgat aatttcccag ctttcagcat
     8641 cagctaaact gtaagtggtg gttgcagatg gcgtaaagtc agctttacgt agaatagatt
     8701 ggatacgagc gtgagcgtat tgaacataag gtccagtttc tccttcaaag gaaaccatgg
     8761 cctcaaggtc aaagtcatac ccattcatac gatctgtttt gagatcgtaa aacttgatgg
     8821 caccgacacc aacagcgtgt gcaacagctt ctttgtcagc aaggtttgga tttttcgctt
     8881 caatttgaga agctgcacgg ttaatggctt cagcaaccgt aggttcaaga agaataacat
     8941 tacctttacg tgttgataat ttagcaccgc cttttgtgac aagtccaaaa gcaacgtgtg
     9001 tcatatcatc tgaccaatcg taacccattt cttttagcac tgcttttaat tgtttgaagt
     9061 gagcagcttg ctcattacca acaacataaa cggatttagc aaagtcataa gtgcgtttac
     9121 ggtaaagtgc ggcagctagg tcacgggtaa tgtaaagagt agcgccatct gattttttga
     9181 tcaaggcagg gtgttcaata ccatattttt caagattaac aacttgggca cctttagatt
     9241 ctacaagaag gtttttagct tctaataagt caagaacctc atccattttg tcattataga
     9301 aggcctcacc gttgtaacta tcgaaggtga catgtaattg gtcataaagt cggttgaact
     9361 caagtaaact ttcatcacgg aaccattgcc ataattcagt agcttctttg tcgccatctt
     9421 ccaatttacg gaaccattca cgagcttctt catcaacggt gggatcagtt tcagcttcag
     9481 cattgatacg aacgtaaagt tttaagagtt catcaatagg atgtgcctga acagcagctt
     9541 catctcccca ttttttgtag gcaacaatga gcataccaaa ttgtttaccc cagtcaccaa
     9601 ggtgattgat ttttacaggt ttatagccca ttttggcaaa aatgtgagcg agactatcac
     9661 caataactgt tgagcggagg tgaccgattg aaaatggctt agcgatgttt gggcttgaca
     9721 tgtcaatagc aacatttcgc ccttgacctt cgtcttgctg agcatagtct gaacctgctg
     9781 taatcacttg ttcaaggacc tgtgaggaaa tcttagcttt atcaaggaaa aagttgatgt
     9841 aagggccgac agctacgact ttttcaaatt ggctctcatc aatctgttca gctaactcgc
     9901 tagcaatcat ttgaggggct ttgcgaagga cttttgctaa gctaaaagct ggaaaggcaa
     9961 ggtctcccat gtcagaattt tttggggttt caagcaagtt aaaaatagca tcttgttcta
    10021 attctggaac aactttagct atttcacttg cgattagagt tttagtatcc atacagcgtc
    10081 tcctaaaaat tgtttgtcac cctattctaa catatttctt taaaataaac gaggagagga
    10141 ttgataaatt atactgaaac tttcaaggaa atgaattgct tgaggttgtt gtttttctga
    10201 aaatgttata aaaagagaaa tgaggtttct tttcaacagt tttcaagtga aattctagtt
    10261 gaatttgata aaaaattgct gaaaatagct gggcgaagat gaaataatac actttttttg
    10321 ttataatttg agaggataat tatacaattg gggtgatata tcatgaataa aatggagcgt
    10381 caacagcaga ttaagcgaat cattcaagca gagcatattg gcacacaaga agatattaaa
    10441 aatcaccttc aaaaagaagg cattgtggtc acccaagcaa ctctatctcg ggacttaaga
    10501 gaaattggcc ttttgaaatt gagagatgaa caaggcaaac tctattatag tttgtctgaa
    10561 cccgttgcaa caccatttag tcctgaggtg cgtttttatg ttttgaaagt tgatcgagca
    10621 ggttttatgc tggttctcca taccaattta ggagaggctg atgttctagc taatttgatt
    10681 gacaatgatg ccattgaaga tattctagga accattgctg gtgcggatac cttgcttgtg
    10741 atttgcagag acgaagagat tgctaaacgc tttgaaaaag atttggctgc aggcctatga
    10801 ctagctatta agagtctttg acacaattga ttcttgctat ccatgaattc tagtatcgtt
    10861 gcttataaag aagtgcagca atagctgtct aagctccatg attttaaaaa gtaagcttat
    10921 cagatgaaac gctatcaaca agatgccctg cttttcaaaa aaaatagata aagaaaaggc
    10981 tgcgacagta tctgcaagca gggcaaaaga actagaagat aggctcagtc atcagccatt
    11041 aattgatgat tatcgagaaa agatgcaaga tgcaagtgat gtgattcagt atatcaccaa
    11101 acgtatagaa gatcagttaa acaaggagtt aacaaatggc aaaaactaac atttctcctg
    11161 gaatgcaaca gtatctggac atcaaaaaag attatccaga tgcttttttg ctttttagga
    11221 tgggtgactt ttatgaatta ttttacgagg acgctgtcaa agcagcacaa ctcttagaaa
    11281 ttggtttgac cagtcgcaac aagaatgcgg aaaatccaat tcctatggca ggcgtgccac
    11341 atcattctgc ccaacaatac attgatgtgt taattgagtt gggttacaag gttgctgtcg
    11401 cagaacaaat ggaagaccca aagcaagctg ttggggtggt gaagcgtgag gtcgttcaag
    11461 tcataactcc tggaacggtt gtggattcag ctaagccaga tagcgccaat aactttttgg
    11521 tagctgttga ctttgatggt tgccgttatg gattggctta tatggatgta tccacaggtg
    11581 aattttgcgt gacagatttg gcggacttta cgagtgttcg tagcgaaatc caaaacctca
    11641 aggcgaaaga agtcttacta ggttttgatt tatctgaaga agaacagacg attttggtca
    11701 agcagatgaa tttgctgctt tcttatgaag aaacggtcta tgaagataaa tctttaattg
    11761 acggccaatt gacaacggta gaactgacag cggcaggaaa actcttgcaa tacgttcaca
    11821 aaacacaaat gcgagaactc agccacttgc aagcattggt tcactatgag atcaaggatt
    11881 atttgcagat gtcgtatgcc actaagtcaa gtttagattt ggtagaaaat gctaggacta
    11941 ataaaaaaca tggaagtctc tattggctgt tagatgaaac caagacagct atggggatga
    12001 ggcttttgcg ctcatggatt gatcgacctt tggtttctaa agaagctatt ttagagcgtc
    12061 aagaaattat tcaagttttt ctgaatgctt ttattgagcg aaccgattta agcaatagtt
    12121 taaaaggtgt ttacgacatc gaacgcttat ctagtcgcgt gtcttttggc aaggcaaatc
    12181 cgaaagattt acttcaattg gggcatacct tagctcaagt gccttatatc aaagctatct
    12241 tagagtcttt tgacagtcct tgtgttgaca aacttgtcaa tgatattgac agtttgcctg
    12301 agttggaata cttgattaga acagccattg atccagatgc accagcaact attagtgaag
    12361 gaagtattat ccgcaatggt tttgatgagc gcttggacca ttatcgtaaa gtaatgcgag
    12421 aggggacagg ctggattgcg gatattgagg ccaaagagcg tcaagcaagt ggcattaata
    12481 acctaaaaat tgattacaat aaaaaagatg gttattattt tcacgttacg aattcaaatc
    12541 ttagcttagt tcccgagcat tttttcagaa aggcaacttt aaaaaattct gaacgttatg
    12601 gaacagcaga attggctaag attgaaggtc agatgttaga ggctagggaa gagtcatcta
    12661 gtttagaata cgatattttt atgtgtattc gagctcaagt tgaaacctat attaatcgtt
    12721 tacagaaact ggctaaaatt ttggcaacgg tagatgtttt gcaaagttta gcagtcgttg
    12781 ctgaaaccaa tcattatatc cggccgcagt tcaatgataa tcatgtgatt acaattcaag
    12841 aaggtcgtca cgcggttgtt gaaaaggtta tgggagtgca ggaatacatt cccaatagta
    12901 tctcttttga ccaacagacc agtattcagc tgattacagg tccaaatatg agtggtaagt
    12961 cgacttatat gagacagctg gccttaacgg ttatcatggc ccagatgggt tcatttgtgg
    13021 ctgctgatca tgttgattta cctttatttg atgcgatttt tacgcgtatt ggggctgctg
    13081 atgatttgat ttctgggcaa tcaaccttta tggtggagat gatggaagca aaccaagcaa
    13141 tcaaacgcgc aagtgacaac tctcttattc tatttgatga actgggacga ggcacggcaa
    13201 cttatgatgg tatggcttta gcccaggcaa ttattgaata tatccatgat agagttggtg
    13261 ctaagaccat atttgcaacg cattatcatg aattgacaga cttgtcaact aacttgacaa
    13321 gtctagtcaa tgttcatgta gcaacgcttg aaaaagatgg cgatgttacc ttccttcata
    13381 agattgctga gggaccggcg gataaatctt acggtattca tgtggcaaaa atagcaggac
    13441 tgccaaaatc cctattaaag agagcagacg aagttctgac ccgtttagaa acacagtcac
    13501 gatctactga gataatatca gtcccttcac aagttgagtc aagcagcgct gttagacagg
    13561 ggcaattatc cctttttggt gatgaagaga aagctcatga gattaggcaa gcactggaag
    13621 ttattgatgt catgaacatg accccgcttc aagcaatgac aactctttac gaattgaaaa
    13681 agttgttata gtctttcagc tgaaaatgaa aaagatgctt tctatattga aggcatcttt
    13741 ttgttctgtc aaaaacggtc cgaggccttc ggctatttat taagtgtgtt ataatagtcc
    13801 ataagaatgc gaggaaatta tgacaaacat tattgaatta ccggaagttc tcgccaacca
    13861 aattgcagct ggtgaagttg tagaaaggcc agcgagtgtt gtcaaggaat tggttgagaa
    13921 tgctattgat gctaaaagta gccagattac cgttgaaatt gaagagtctg gccttaagat
    13981 gatacaggtt acagacaacg gtgagggaat gtctcatgaa gatttacctt taagtctgcg
    14041 tcgccacgct actagtaaaa ttaagagtca gagtgatttg tttagaatta gaacacttgg
    14101 cttccgtgga gaggctttac cgtctgttgc ctctatcagt aaaatcacga taaaaacagc
    14161 aacaaaagaa gtcactcacg gttctcttct tatagctact ggtggggaaa ttgagacact
    14221 tgaagcgatc tcaactccta ctggaaccaa aattaaggtt gaaaaccttt tttacaacac
    14281 gcctgctcgt ctcaaatata tgaaaagttt acaggcagaa ttagctcaca ttgtagatgt
    14341 ggtcaaccgg ttgagtttgg cacatccaga agttgctttc acactgatta gtgatggtcg
    14401 ccaattaact cagacatcag gaactggcga tttacgccaa gcaattgcag ggatttatgg
    14461 tttgaatact accaaaaaaa tgctggctat ctctaatgct gatttggatt ttgaagtttc
    14521 cggctatgtt agcttgccag agttgacacg cgccaaccgt aattacatga cgattttggt
    14581 taatgggcgt tacatcaaga atttcttgct taatcgagca attcttgatg gttacggttc
    14641 taagctcatg gttggacgtt tcccaattgt tgtgattgat attcagattg atccctattt
    14701 ggccgatgtc aatgttcacc ccacaaaaca agaggttcgt atttcaaaag agcgtgaatt
    14761 aatggcttta attagcacgg ctatttcaga gagtcttaag gaacaagatt tgattccaga
    14821 tgctctggaa aatttagcca aatcaagcac acgacatttc tctaaaccag agcaaacaca
    14881 acttccttta cagtctaggg gactttatta tgatcctcaa aagaatgact tttttgtcaa
    14941 agagtcggct gtctcggaaa aaatacctga aactgatttt tattccggcg ctgttgacaa
    15001 cagtgtaaag gttgaaaaag tagagctgtt accccactca gaagaagtta taggaccttc
    15061 ttcggttaaa cacgcaagtc gtccccagaa tacctttacc gagactgatc atcctaatct
    15121 tgacttaaaa aacagacaaa agttatctca aatgctaacc cgtttggaaa atgaagggca
    15181 atcagtgttt cccgaattgg attattttgg tcagatgcac ggaacttatc tctttgctca
    15241 gggaaaagat ggtttattta taattgacca acacgctgcc caggagcggg ttaaatacga
    15301 atattatcgt gataagatag gtgaggttga cagtagttta cagcaattgt tggtgcccta
    15361 tttgtttgag ttttctggtt ctgatttcat taacttacag gagaaaatgg cactcttaaa
    15421 tgaagttggt atcttcttag aagtttatgg gcacaatact ttcattttga gggagcatcc
    15481 tatctggatg aaagaagaag agattgcatc tggtgtctat gaaatgtgtg acatgttact
    15541 tctaaccaat gaggtatcta ttaaaactta ccgagcagag ttagctatta tgatgagttg
    15601 taaacgatct atcaaggcaa atcatagctt ggatgattat tcagcaagaa atctgctact
    15661 gcaattggcc caatgtcaaa atccttataa ctgccctcat ggtagacccg tattgattaa
    15721 ttttagtaag gcagatatgg aaaaaatgtt ccgtcgaatt caagaaaatc acactagcct
    15781 gcgagagcta ggaaaatatt agagaggatg agatgcaaga gtttttaaac cttcctaagc
    15841 agattcagct gaggcaactg gtacgctttg tgaccattac cttaggcagt agtatctttc
    15901 cctttatggc catgtattat acgacttact ttggtacgtt ttggacaggc ctcttaatga
    15961 tgattaccag tttgatggga tttgttggaa ctttatacgg tgggcatctg tcagatgctc
    16021 ttggtcgcaa aaaagtcatt atgattgggt cagtaggaac aacactaggc tggtttctga
    16081 ctattttagc taatttgcct aatgcggcta ttccttggtt aacctttgcg ggtattttat
    16141 tggtagagat tgcttctagt ttttatggtc ctgcctatga agctatgttg attgatttga
    16201 ctgatgagag taatcgtcga tttgtttaca ccatcaatta ttggtttatc aatattgccg
    16261 tcatgtttgg tgcagggcta tctgggcttt tttatgacca tcatttttta gccttgttag
    16321 tagccttatt actcgtcaat gtactttgtt ttggcgttgc ttactactgt tttgatgaaa
    16381 ctagaccaga aacacacgct tttgaccatg gtaaaggatt actggcgagt tttcagaact
    16441 accgtcaggt gtttcatgat cgtgcctttg tcttgtttac cttaggtgcc atcttttctg
    16501 gtagtatctg gatgcagatg gataactatg tgccagtcca tttgaaactg tattttcagc
    16561 caacggctgt gttaggtttc caagtaacta gttctaaaat gttatcatta atggttttaa
    16621 ctaatacatt gctgattgtc cttttcatga cagtagtaaa taaattaacg gaaaaatgga
    16681 aactattacc tcagcttgtg gttggttctt tactatttac tctagggatg ctcttgtcat
    16741 ttacctttac gcagttctat gctatctggt tatcagttgt tttgttaact tttggggaaa
    16801 tgataaatgt ttctgctagt caagtcctac gtgctgatat gatggatcat tcccaaatag
    16861 gatcttatac aggttttgtg tcaatggcac aacccctagg tgctattttg gctagtctac
    16921 tagtatctgt cagccatttt acaggtcctt taggcgtgca atgcttattt gcagtcattg
    16981 ctttgctagg gatttatttt acggttgttt ctgcaaaaat gaaaaaggtg taatatgtac
    17041 gattatatta aaggtcaatt gaccaaaatt acggcaaaat acattgtcgt tgaagctaat
    17101 ggattgggct acatgattaa tgttgccaat ccttatagct ttacagatag tgtcaaccaa
    17161 ttggtaacca tttatctgca tcaagtgatt cgtgaggatg ctcacctgtt gtttgggttt
    17221 cacacggaag atgaaaaaga tgtttttctg aaattaattt ctgtatcagg tattggtccg
    17281 acaacagctc ttgctattgt ggcagttgat gataatgagg gacttgtgaa tgccattgat
    17341 aacagtgaca ttaagtacct aatgaaattt cctaaaattg gtaaaaaaac agcgcagcaa
    17401 atggttcttg acttagctgg caaatttgtg gaggctccac aagagactgg tcataccaaa
    17461 gcgcgcagca ataaagcagg caatactcaa ctggacgaag cgattgaagc cctccttgct
    17521 ctcggttata aagcaaaaga gctgaaaaaa attcgtgcct tctttgaggg gacctctgag
    17581 acggcagagc aatacatcaa atcagcattg aaactgttaa tgaaagggta ggtgtttcac
    17641 atgaaacgtt gctcatgggt tcctaaggat aaccagcttt actgtgatta ccacgattta
    17701 gaatggggtc aacccctgga tgatgataga gatttttttg aattgctgtg ccttgaaagt
    17761 taccagtcag gcttatcctg gctgactgtt ttgaaaaaac gccaagcttt cagaactgtt
    17821 tttcatcatt acgacattgc atcggttgca acctttacct cggaggaaat ggctgatgct
    17881 ttagagaatc catccattat ccgccacaag ctaaagctag cagcaactgt caacaacgct
    17941 atcgcagtac agaaaattca aaaagagttt ggtagttttt caacttatct ctggaatttt
    18001 gttgggggaa agccaattaa caaccttgtc aatcaagaga atcttgttcc tgctcaaaca
    18061 gaattatcta ttcgcttagc taaggattta aagaaaagag gatttaaatt tttagggcct
    18121 acaacggttt attcttttat gcaagcatcg ggtctggtaa atgaccatga agaggcttgt
    18181 gttttcaata gaatcttcta attcttcgtg aattggaaga ttttttgata aaatgagatc
    18241 agattacgaa tagataagta ggtagggaaa tgaaagctga actgattgca gtaggtaccg
    18301 aaattttgac tggtcaaatt gtgaatacca atgctcaatt tctgtcggaa aaaatggcag
    18361 agctaggtat tgatgtctat tttcaaacgg ctgttgggga caacgaggag cgtttacttt
    18421 cagtgattac aactgctagt cagcgtagta acttggtaat tttatgtggt ggccttggtc
    18481 caacgaaaga tgatttaacc aaacaaactt tagcaaagta ccttaggaaa gacttggttt
    18541 atgatgagca agcttgtcag aaactagatg acttttttgc taagcgcaag ccttcatcac
    18601 ggacaccaaa taatgagcga caggcacaag tgattgaagg gtcaatccct ttgccaaata
    18661 aaactggtct tgcggttggt gggttcatca cagtcgatgg tattagttat gttgtcttac
    18721 cgggtcctcc aagtgaattg aagccgatgg taaatgaaga attggtacca cttctgtcaa
    18781 aacaatacag tacattgtat tcaaaggtac tacgcttttt tggtattggg gaaagtcagt
    18841 tggtaacagt cttgtcagat tttattgaga atcaaactga tccaaccatt gctccgtatg
    18901 ctaagactgg cgaagtgact cttcgcttat caacaaaaac tgaaaaccaa gctctggcag
    18961 ataaaaagtt aggtcagcta gaagcgcagc tactatcccg aaaaactctt gaaggtcaac
    19021 ccttagctga tgtcttttat ggctatgggg aggataattc cttagcgcgt gagacatttg
    19081 agctcttagt aaaatatgat aagacaatta cagcagcaga aagtctaacc gcgggattat
    19141 ttcagtcaac tttggcgagt tttccaggag cttctcaagt attcaatgga ggctttgtga
    19201 cttatagcat ggaagaaaaa gcgaaaatgc taggccttcc tttagaggag ttgaaatcgc
    19261 atggcgttgt tagtgcttat acggccgagg ggatggcgga gcaagcaagg ttattgactg
    19321 gtgctgatat tggggtaagt ttaacaggtg ttgccggacc agatatgttg gaggaacagc
    19381 ctgcaggtac agttttcatt ggtcttgcca ctcaaaataa ggtagaatca ataaaggttt
    19441 tgattagcgg gcgaagtcgt ttggatgtgc gctatatcgc tactttacat gcttttaata
    19501 tggtccgtaa aactttatta aaacttgaga atttgctata atgttattta gtagctatag
    19561 taggatatgg tttacaatta tgtagattaa tcctgctgac gatggtttgt taaaaaagag
    19621 gagaaagtat tggcaaaaaa attaaaaaag aatgaagaaa tcactaagaa gtttggtgac
    19681 gaacgtcgca aagcccttga tgatgctttg aaaaatattg aaaaagattt tggtaagggt
    19741 gcagtgatgc gattaggaga acgtgcagag caaaaagttc aggttatgag ttcaggaagt
    19801 ctagctcttg atattgcgct tggagctggt ggttatccta aaggacgtat catcgaaatc
    19861 tatggtccag agtcttccgg taaaacgact gtggctttac atgctgtagc acaagctcaa
    19921 aaagaaggtg gaatcgcagc ctttatcgat gccgagcatg cgcttgatcc agcttatgct
    19981 gctgcgcttg gggttaatat tgatgaactc ctcttgtctc aaccagattc tggagaacaa
    20041 ggacttgaaa ttgcaggtaa attgattgat tctggtgcgg ttgatctggt tgttgtcgat
    20101 tcagtagcag ctttagtgcc acgtgctgaa attgatggtg atattggcga tagccatgtc
    20161 ggattgcaag cacgtatgat gagtcaggcc atgcgtaaat tatcagcttc tattaataaa
    20221 acaaaaacta tcgctatctt tattaaccaa ttgcgtgaaa aagttggtgt gatgtttgga
    20281 aatcctgaaa caacaccagg tggtcgagct ttgaaattct atgcttctgt tcggctggat
    20341 gtgcgtggaa caactcaaat taaaggaact ggtgaccaaa aagatagcag tattggtaag
    20401 gagaccaaaa tcaaggttgt taaaaacaag gtcgctccgc catttaaggt agcagaagtt
    20461 gaaatcatgt atggggaagg tatttctcgt acaggggagc ttgtgaaaat tgcttctgat
    20521 ttggacatta tccaaaaagc aggtgcttgg ttctcttata atggtgagaa gattggccaa
    20581 ggttctgaaa atgctaagcg ttatttggcc gatcacccag aattgtttga tgaaatcgac
    20641 cttaaagtac gtgttaaatt tggtttgctt gaagaaagcg aagaagaatc tgctatggca
    20701 gtagcatcag aagaaaccga tgatcttgct ttagatttag ataatggtat tgaaattgaa
    20761 gattaaaaag agcccttcag ggctttttaa aatgtatttt taaaggttag taggactact
    20821 gttcataggt gtgtgggtga atagaaacca tcatttaaaa agatgtgaga gagcagaact
    20881 taggttaact gatataaaat taaaataact aataattcaa gggaatacag gtgaaaaacc
    20941 ttattttaca aagataatat ctttaaaatt aaaaaaatag gtccaaagac ctatatttat
    21001 agataagaaa ctgtgctaca ataaagctat cacgaaatag aaagtgagtc agcaacatga
    21061 ttaaaattta cacgatttca agttgtacga gctgcaagaa agccaaaact tggctaaatg
    21121 cccataagct tgcttataaa gaacagaact taggaaaaga accgctaact aaagaagaaa
    21181 ttttagcaat tttatcaaaa accgaaaatg gagtggagag cattgtttca tctaaaaatc
    21241 gttatgccaa agctctcgat tgcgatattg aagaattaag tgttagtgag gttattgatt
    21301 tgattcaaga taacccgcgc atccttaaaa gtcccatttt gattgatgat aaacgtctgc
    21361 aagtaggcta caaagaagac gatattcgtg cttttttacc tcgctctatt cgtaatattg
    21421 aaaatactga agcacgatta cgtgctgcac tctaaaagct cttgtagagc tttttttaaa
    21481 taccttcttc gcttgaaatt cttgtttatt taatagaaat aagctataat aaagcatagc
    21541 acttaatttt agaaagaagg tgtaagtatg ggatttacag atgaaacagt ccgctttaag
    21601 ttggatgatg gcgacaaacg acaaattagt gaaacattaa cagcagtcta tcattcactt
    21661 gatgaaaagg gttataatcc aattaatcaa attgttggtt atgtcttgag tggggaccca
    21721 gcttatgttc ctcgttataa tgatgctcga aatcagattc gtaaatatga acgtgatgaa
    21781 attgtagaag aacttgttcg ctactattta caaggaaatg gaattgatgt taaatgagaa
    21841 taatgggact tgatgttggc tcgaaaacgg ttggtgtagc tattagtgat cctcttggct
    21901 ttacagccca aggacttgaa attatcaaga ttgatgagga aaaagcagaa tttggcttta
    21961 cacgtttaga agagcttgtt aagcagtacc aagttgaaca gtttgttatt ggattgccaa
    22021 aaaatatgaa taacaccaat ggtccacgtg ttgatgcaag tataacttat ggaaaccaca
    22081 tagagcacct ctttggactt ccagtccatt atcaagatga acgattgacg actgttgagg
    22141 caaagcgtat gcttattgag caagctgaca ttagtcgtgg taagcgaaaa aaagtcattg
    22201 ataaattagc tgcacaactc attttacaga actatttaaa tcggaatttt taaggagata
    22261 aaaaatgaca cataatcatg aaaatgacca ccaacacgaa gttatcacac ttgtggatga
    22321 acaaggaaat gaaaccttgt ttgaaatttt attaacaatt gatggtcgtg aagagtttgg
    22381 taaaaattat gttctcttgg ttccagcggg atctgaagaa gatgagtctg gtgaaattga
    22441 aatccaagcc tattcattta ctgaaaatga agatggtact gaaggggatt tacaaccgat
    22501 tcctgaggat tcagatgctg aatgggatat gattgaagag gtatttaata gttttctaga
    22561 tgagaactaa attgttagtg acactatgtt aaaaagtagc cgtgagggct atttttttaa
    22621 tgttattttc gaataaataa gcaggaggtg ataatgataa aagaattaaa tgataaattt
    22681 attaataatt ataaggctaa acctttgcat atatttagag aattattaca gtatgtgaaa
    22741 atatatcaga aattgactaa ataaaagatt ctgttatact tgttttataa tattctttga
    22801 cgataatatc atttttcaac ttactttgtt tatgtactgt cactttgcta tgtgcaatac
    22861 aaagtcatgt tatttatctc atactaaaaa ataatggata atagctatgt tagactagtg
    22921 atatgaagaa atattgcttt tattgaatcg ttagagaata tgatatttca aggagaaaaa
    22981 tagtgatcga gttaaacgat gaattcatcc gaaaagagac gatagaactg gccaacgatg
    23041 gcccacgagt acacaccact caatatgaaa ctaaagtacc tcggcttcat aaatgctatc
    23101 tgcttttctt tagcattatt atcagttctt taacaattgc agtacctttt ttaacagatg
    23161 cagccaatgg tcttcagtcc caaaacttat atataggaat gatgttaacg aaggggcaac
    23221 ttccctatag tgctgctttt acaacaggag ggctctttta ctttgttatc attgcattaa
    23281 gttattattt gggatcgaca ctttggctag tctttgttca ggtgttttgt ttttacttat
    23341 ctggtttata tctttataaa ctcattaatt atatgacagg ctttcaaaaa gtggctttaa
    23401 ctttttcaat tagctactat ttattatctg ttagtcttgg ttttggggga ttgtatccta
    23461 ctcaactggc tatgccattt atattaatat cggcttggtt tttaactaag tattttgcct
    23521 gtttagtgaa agatgaggca tttattcttt ttggctttgt aggtgctctt gcaatgctaa
    23581 ttgacccgag tacccttatc ttttggtctt ttgcttgtgt gacagttttt tcttataata
    23641 taagccaaaa gcatcttgca agaggttttt atcaactgct agcttcgatt tttggaatga
    23701 ttttagtttt ttacacagca ggatatttca ttttgaactt acaagtgcta aatccttatt
    23761 tatcacaaac gatgatttat ccttttactt tttttaaatc aggaaactta tcgttgcttt
    23821 ttggactggc tattcagttg ttcttcgctt tggggcttgg tcttttgacg ggaatggaga
    23881 atgtcattag gcgatttaaa aacaattctg atagggtcgt caagtggcta tttgtcatgg
    23941 tcattctaga atctatactt gtggctatat tttcacaaga ctatcgcccc tatcatcttt
    24001 tacctctttt accttttgga ttaattttga ctgctattcc tgttggctat cagtatggta
    24061 taggattagg tcagagtagt catcgcagac gtcatggtaa aaatggtgtt ggtcgagtaa
    24121 tgatgattta tcttaagaga cacttttatt tgccaatttt aattgtaggg acaatactaa
    24181 tctgttctac ttattgtttc attagtagta ttcctcttaa tcaggagcgt gatcatattg
    24241 ctagttattt agaacagaaa ctaaataaaa ctcaatctat ttatgtttgg gatgatactt
    24301 ctaaaattta tttggacagt aaagctaaat ctgtttctca atttagttct cctgacatca
    24361 atacgcaaaa agagagtcat cgaaaaatat tagaagatga actattagaa aataaggctg
    24421 cttatatcgt tgttaatcgc tataaaaacc tgcctaaaat cattcaaaaa gtattatcta
    24481 ctaattacaa agtagataaa cagataacga caaaaagttt tattgtttat cagaaaaagt
    24541 aatttaatat caatatattg tgttcgagca aaaaacttga cacaatatat tgattttttt
    24601 agttgtcgtg atataatagt tccgtaagga gatttgatat ggtaagttta gaagaagaca
    24661 aggtgactgt tcaacctgat attaaagtga ttaaacgaga tggtcgcctt gttaattttg
    24721 atagtacaaa aatctatagt gctttattaa aagcaagcat gaaagtaact cggatgtcgc
    24781 cacttgttga ggctaaatta gaggctattt ctgatcgcat tatagcagaa attattgagc
    24841 gttttccaac taatatcaaa atttatgaaa tccaaaatat tgtagagcat aagcttcttg
    24901 cagctaatga atatgctatt gcaaaagaat acattaatta tcgtactcag cgtgactttg
    24961 cacgttcaca agcaacagat atcaattttt ctattgataa attaattaat aaagatcaaa
    25021 cagttgttaa tgaaaatgct aacaaagata gcgatgtttt taatactcaa cgagatttaa
    25081 ctgctggaat cgtagggaaa tcgattggtt taaaaatgtt accttcgcat gttgctaatg
    25141 ctcatcaaaa aggagatatc cattaccatg atttggatta cagtccttat acaccgatga
    25201 cgaactgctg tttaattgac tttaagggca tgttagccaa tggctttaaa attggtaatg
    25261 ctgaagtgga aagtcccaag tctattcaaa ctgcaacagc tcagatctca cagattattg
    25321 cgaatgtagc atcaagtcag tacggcggat gcacagctga tcgcattgac gagtttttag
    25381 ccccatatgc ggagcttaac tttaaaaaac atatggctga tgctaagaaa tggatcgttg
    25441 agactaagag agaaagctat gcttttgaaa agactcaaaa agatatttat gatgcgatgc
    25501 agtctttgga gtatgaaatt aatacgctct ttacgtctaa tggtcaaaca ccatttactt
    25561 ctttaggatt tggtttgggg acgtcttggt ttgaacatga gattcaaaaa gctattttga
    25621 ccattcggat taatggtctt ggtagtgaac atcgcacggc tattttccct aaattaattt
    25681 tcacggttaa acgtggcttg aatttagaac cagattcacc aaactatgat attaagactt
    25741 tggctttaga atgtgcgact aagcggatgt acccggatat gttatcttat gataaaatta
    25801 ttgatttgac aggatctttc aaatctccaa tgggatgccg ctctttcctt caaggctgga
    25861 aagatgaaaa tgggcaagat gtgacctcag gccgtatgaa tcttggggtt gtcaccctca
    25921 atttacctcg cattgccatg gaatcaaatg gcgatatgga taagttttgg gagctgttta
    25981 atgagaggat gctaattagt aaggatgctt taatttatcg tgtcgaacgt gtcacagaag
    26041 caaaaccagc aaatgctcct attctttatc aatatggtgc ttttggaaag cgtttggaga
    26101 agacagggaa tgtaaatgat ctctttaaga atcgtcgtgc aacagtctct cttggctata
    26161 ttggtcttta tgaagtggcg tctgtttttt atggtggtca atgggaaggt aatccagatg
    26221 ctaaagcttt taccttgtca attgtcaagg caatgaaaca ggcctgtgag gattggtcag
    26281 atgaatatgg ttatcatttc tctgtttatt cgactccatc agaaagtttg acagatcgct
    26341 tttgtcgttt agatacggaa aaatttggca ttgtgacaga tattacggat aaagaatact
    26401 atacaaattc ttttcactat gatgtgcgta agagtccgac accttttgaa aaattagatt
    26461 ttgaaaaaga ttatccagaa gcaggtgctt caggtggttt tatccactac tgtgagtatc
    26521 ctgttttgca acaaaatcca aaggccttgg aagcggtttg ggactatgct tatgatcgtg
    26581 tggggtattt gggaaccaat acgcctattg ataaatgcta taattgccaa tttgaaggcg
    26641 attttacccc aacagaacgt ggttttactt gcccaaactg tggcaataat gaccctaaaa
    26701 cagttgatgt ggtcaaacgt acatgtggtt acttggggaa tcctcaggcc cgcccaatgg
    26761 ttaacggtcg ccataaggaa atctctgcgc gtgtaaaaca tatgaatggt tctactataa
    26821 aatacccagg cctgtaaact caagctgggg gagagccctt ttgatggaaa tatgatatgc
    26881 ttaaaaggtt gcttcatgca agcaatcttt tattgtttaa tggtttctta gcaattgtga
    26941 gataagaata actaatccaa aatgactaat tagctgttag caatcggact ataagaagaa
    27001 agagataagg aagaaataat gggaaaatat caattagact ataaaggaat gcagcaggta
    27061 gaacgctttc atgagaagca ttctaaaaaa aagacggata aaaaatcccg cgttcaagaa
    27121 cttaaggctc ggtttttaga gaagtcaaaa aaacaggata actaaagtat ccagtaaaga
    27181 aagaaggttg agtatgctta atattgggat tgtgggacta ggtgctattt cacaaaaagc
    27241 ctatttacca tatatgagac agctgagtga cattacttgg catctatcaa cgcggaatgc
    27301 agcagtacgt cagcaggtcg gtcagttatt tggtcacgct attctttaca gtgatgtcaa
    27361 ggagttgtca aaaacaaact tagatggggt ctttattcat gcggccacat cggcccacgc
    27421 agagttggct agtttatttt taaatcaggg gatcccagtc tttatggata aacctatagc
    27481 tgacaattac ctgatgacaa agaacctcta tgacttagcc aaagaaaatc agacttttct
    27541 gatggcagga tttaacaggc gttttacacc tcgtgtcaag aagttgtcaa gtttgtcaac
    27601 taagcgtaaa gtggctgttg aaaaaaatga cttgaaccgg ccaggagata tgacttttaa
    27661 gctctttgat ttctttatcc atcctttaga tacagcctta ttcttgacag aagggacctt
    27721 actaaaaggg cattttcaat atcatctgga agcaggctta ctgagtcaag ttatggtaac
    27781 cttgatgacc gaaagcatga cgactacagc ttctatgaat ttacaatcag ggagtcgccg
    27841 tgaggtaatg gaagttcaac gggctgaaga aacttatcat ttagagaact tagacgagtt
    27901 atctatttat aaaggtactg aaaaaagggt gcttggcttt gcttcttggg acactacctt
    27961 gcacaaaaga ggttttgaaa caatgatcga tgccttttta gaagctatta gcacaggcgt
    28021 caatcctgtc agccctgagt ctagtctttt aagccactgg atttgtcaac agattgctga
    28081 ctctcagctt tcttatggag agttaacggt agagttgcct aaggattagg aattgatatg
    28141 gaaataagac gaccgacttt aaaagataaa gacgctgtat tgtcaatgat taacgaattt
    28201 ttagagcaga aaagtgctac agatgggtta tggcatttta acgtcaatga ctttaactat
    28261 gaaacatggt tggaagattc cttgcgacag gaaatgggtt tgtccagtca aggagtgcct
    28321 gctattcaat acgtcgcatt tgatgagaga agtcaggcta tcgggttctt aaatcttcgt
    28381 ttacggttaa atgagagatt acttgaaaaa ggtgggcata ttggttactc tgtccgtccc
    28441 agccagcgtg ggaaaggtta tgccaaggag atgcttaaac aagctgtcag ctatgcgatt
    28501 tccaagaata tcacgacaat tttggtaact tgtgatgaga ctaatattgc aagccgagca
    28561 gttattgtgg ctaacggcgg tatcttggaa gatagtcgag gtggaacgga acgttattgg
    28621 attgaagaac aaagaggcga taagtgatgg cagaaaagtg ttggaataat cctaagccaa
    28681 aggaatggca ggcagaggag ttaagtcaag gccggattat tgactataag gcttttaact
    28741 ttgttgatgg tgaaggggtt cgtaattccc tttatgtgtc tggttgttta ttccattgca
    28801 aggggtgtta taatgctgcg acttggtctt ttaaggcggg aatgccttat acgcaagaac
    28861 ttgaagagca gataatgacg gatttggcac agccttatgt tcagggactg acacttttag
    28921 gtggagaacc ctttttgaat acgggtatct taattcctct gattaagcgt attcggcgtg
    28981 aattgccaga aaaagatatt tggtcttgga cgggttatac ttgggaagaa atgatgcttg
    29041 aaacaccaga caaactggaa atgctgtcct taattgatat tctggtagat ggtcgttttg
    29101 atatcacaaa aaagaacctc atgttgcaat ttagaggctc ttctaaccag cgaattatcg
    29161 atgttcaaaa gtctttggct gctaaagaag tgattatctg ggataagtta aacgatgggg
    29221 accaaacctt tgaacaaatt agtcgggagg atttgcttta agaagctgac ttatccacat
    29281 gatttttttg aaaaggtcat gtgaaaacag gtcctttaag ggtgaattgg ggagaaagta
    29341 attgttattc cctggttttc cccacattat cctcatagtt atccacaggt tgtgtataag
    29401 ttgtagaatt gtgaataaag actaaaaaag aggcctaggc ctcttttttg atatagacaa
    29461 attcatgatc tgttgatagg tctggatggt agtaaaaacc agcaaagaca aggcttttaa
    29521 ggctgtcaac agtttggcaa ttattttcca tacaggcagt gagaaatgca cctcgtgcct
    29581 tttttgaaat ggtggaatgg gttttgaatt ggccctcttt ttctgccata aacttgggac
    29641 ttatccacaa ttgtttacag tctttggaaa agacatcgtc aaattcactg gataaaaggg
    29701 aaatcacttg gggatgctct ttggcaaact gattataaca gggccgccag taagacttga
    29761 ggctttgtcc ttcaattttt attctggtgt gaaaatcatg gcggtgctct gcgataggat
    29821 gattagcggg aatgataccg taaaaggatg aggtgatgta aacctgctgg gtgaggtaag
    29881 cctgttcttg ggtagtgagc ttatcgcgct tgatatggcg gtacataagg ccattgaaca
    29941 gttggtaggc agggtaagcc aagctttgtt gagaggccat gtcttgccag cgttgctgtt
    30001 cttttttagc tgactcttct ttgatacgat atgatttggc caagtcctcc gtggtcatag
    30061 ctgccatgat ttttaaaatg gcttggctgt cttgtggaag gaggtgtggg tgagattcct
    30121 tagggatcgt catttctttt gcggttggaa ttaaaaaggt tagcatagtg ttattgtagt
    30181 aaagttactt gctttctgtc aagaaaacta gtcttgtcca aggatgacgt tcacacggat
    30241 accttcctcg tcttctgtcg tgaaagaaga agaatcttct tgtaaaatag ctaggccgtg
    30301 taatcttgct tttttgagag tggctgaaaa aagcaggggc gtctcaatgt gaatggtcaa
    30361 gaaggctaag cctggagcac cttcttggtg ttttttgagg taaggggctg accagtgatt
    30421 gaatgcaagg tgatgatagt agttccctga agcaatccag ctagcacttg gaatggtcat
    30481 tttatcgcct aaatcaaaaa ccttttgata gagaagtgaa gaagccagag catttttgac
    30541 actcagatgg acatggcgaa tgcgtgtgtc ttgagctagt aaaaagtgct tggggatatc
    30601 tgtcaactgc tccaatatgc ttttggtatc cgtgggctca gtcacaccaa taatttgacc
    30661 attgtcgcgg atatcccaat gctcaacagc tttgtcatga taaatttcaa tcccattacc
    30721 ctcaggatcg ctgaggtaga tagcttcgct atggccgtga tcagctgctc cttctaaaga
    30781 gatacttctg gttaagaaat gattgagaac aagtcccaag ctatgacgat caggaactaa
    30841 aaaggctgtg tgataaagac cataagcttt atcgcctggt aaaggtgttt gtcgtaactc
    30901 taagataacg gttttaccgt ctgtagtcaa ttgacgagat gtcgtgtctt gtgagagaac
    30961 ctgtaaaccg ataatacttg tgtaaaaggt tgtcatcttt gctagatcgg taacatttag
    31021 agaaaccgtt cctaaagaga tggttgagtt gtaagggtat atcatcctat tacctccaaa
    31081 aactaattaa atctatcata atcaatcagt ttcaaaaaga aaagtaggca caaataagtg
    31141 gtataggcac taaaaagtaa ctcatttgtc agccctatct tgtttctgtt ctctctaata
    31201 gtctataatg ggttataagt tacaaaaaga tactaagagg agctgctgcc tatgctgaaa
    31261 aaaagaccgg cttgtcccgt agaaacaacc ttatcggtaa tcgggaataa atagaaatta
    31321 ttaatattaa gagacttgct aaaggggacc ttgcgttttg ggcagttgaa gtcctcaata
    31381 ggttcggtca gtcaaaaggt acttactgcc caattaaggg ctatggaagc agacggattg
    31441 gttcatcggg aagtgtatgc agaagtgcca cctcgggtgg agtattcctt aacagaaact
    31501 gggttgagct tagctcctgt tattgaagcg atgtcggatt ggggccaaac ttaccaagaa
    31561 aaacatgccg atttatttga agaaggctag aggaaagagt tgtccgagca gactgagact
    31621 tagagaagct gagagttttt aaaaaatgat attatcacat tctttacagt ttgataaaat
    31681 tacttttttt ctacaaaaag acttgcgctc atctcacgaa tatgataata taatatcaag
    31741 tctgtttgag aaaacagaag ctcaggtcaa gtaagtgcac acttacaata acacagttga
    31801 taatggggaa actcagagtc aagaaaaaga aaagcaagcc ttgcattttg caaggctttt
    31861 ttctgtcttt attttggtct gcgccgagca aaatctaaaa atttaaattt ttccagttta
    31921 tggcgactct cggtgaattg gaattggtta ttattggaaa ggtagacttt ggatttgacg
    31981 gaaacaacat gttggtctga tccaaggtca agtaaaattt tatcacgatc ggttatttgg
    32041 tcaatggtaa cctctttgag ggcaaagtca atggcgagat ggagttcctt ttccaaatat
    32101 tgataaatag aatgctctgc gatttccctt gtcattattg gcaccaaagt tttactaagg
    32161 taatcaatgt ctaagacgga agccacaccc tcaacaacgc gttggcgtgt aacacgccag
    32221 accaagctgt ttttgctaaa accggtcaat tttgaaagtg tctcatccac aatcagttta
    32281 tcaatggcaa tgacgttggt cttagaatct agatttgagt aagagacgag ttcctgataa
    32341 ctagttagtt ctgagatagg gaacatgatc tgatgatgtc taatcacttg ggtgccacgt
    32401 ccttgttttt tgaggataag acctgccttt gtgagaagtg agagagcctt gcggacggta
    32461 tctcggctag cttggtattg ttgactcaat tctatttcag taggtaaaaa atccccttct
    32521 ttgtaaaagt ctttgtttat ttttgtttcg aggtctttat aaatacgttc atactttgtc
    32581 atagggtaaa ttacctttcc atttgtctat ttttttacag acaacacctt ttattttacc
    32641 aaaataatgg cttttttggc acaaacaact tgtagacaaa tttgcaatcg attacaataa
    32701 aggtgtcagt tagattctat ctaagaattt gaatatttca ttttgacgtt gcttgttaaa
    32761 agcaactaga acaaaggact aggggatgtc acatgggaaa atttgaacag gatgctaaga
    32821 gtcttctaac tgctattggt ggtaaagaaa acatcaaggt tgtcacacac tgtgcaacgc
    32881 gtatgcgttt tgttttgaat gataataata aggcaaatgt caaagagatt gaaaaaatct
    32941 ctgtagttaa agggacattt accaatgctg ggcagtttca ggtaatcatt ggtaatgatg
    33001 ttccagtttt ttataatgac tttacagctg tttctagtat tgaaggggtg tctaaagaag
    33061 ctgccaaatc agcagctaaa agtaatcaaa atgccttaca acgggtgatg accatgttgg
    33121 ctgagatttt cacacctatt attccggcga ttattgttgg ggggcttatt ttaggtttcc
    33181 gtaatatttt ggagagtgtg ccttttgaat ttcttgggca gcaggtcgaa aaagggaaat
    33241 tagtttttga tgcagctggg gatcctgttt ggaatacgat tgtgagggta tctcctttct
    33301 ggtcaggggt taaccatttc ttgtggttac caggggaagc tattttccac ttcttaccag
    33361 ttgggattac ttggtctgtg acgcgtaaga tgggaaccac tcaaatttta gggattgtcc
    33421 ttggtatctg tttggtgtca ccacaattat tgaatgccta tgcggtggca ggaacgcctg
    33481 ctgctgagat tgccaaaaac tgggtttggg attttggttt ctttaccatt aatcgtattg
    33541 ggtatcaggc acaggttatt ccagcccttt tagctggtct gtcccttgct tatcttgaaa
    33601 ttttctggcg taaacggatt ccagaagtgg tttcaatgat ttttgtgcca ttcctttctt
    33661 tgattccagc tttgatttta gcgcatacgg tattggggcc aatcggttgg actattggta
    33721 aagggatttc ctttgttgtg ttagctggat tgactggtcc tgttaaatgg ctattcggtg
    33781 ctatctttgg tgccttgtat gctccgctag ttattactgg tttacatcac atgacaaatg
    33841 ccattgatac ccaattaatt gctgatactg caactcgtac aactggtttg tggccaatga
    33901 ttgctctttc aaatatcgct caagggtcag ccgtttttgc ttactattta atgaatcgtc
    33961 atgaagaacg tgaggctgaa atatcgcttc ctgcagcaat ttctgcttac cttggggtaa
    34021 ctgagcctgc cttatttggg gttaatgtta aatacgttta tccctttgta gccggaatga
    34081 ttggctcagg tattgcgggt ctcttatcaa caacctttaa tgttcaggca aattctattg
    34141 gtgttggtgg tttaccaggt ttcatggcta tcaatgtgaa gtacatgatt ccattcttca
    34201 tctgtatggc agtagccatt gtggtgccga tgtttttaac cttctttttc cgtaaatcac
    34261 atatcatgac taagacagaa gatgaagcta aactacctga gacacccgtt tcggatgctc
    34321 ctgtagcaac tgctccacat aagactatgc aaggaacagt tatcacttta acaagccctt
    34381 taacgggtga agttaaagcg ttgtctgaag ctgttgatcc tgtctttgca cagggagtta
    34441 tgggccaagg tgctcttctt caaccgacag aaggggtgtt agtagcgcct tgtgatgctg
    34501 aagtatcggt cttgttccca actaaacacg ctatttgttt ggtgacgact gaaggtttgg
    34561 aattattgat gcatattggc atggatacgg ttaacttaga tggtcaagga tttgaagctt
    34621 tggtgaagca aggtgatcag gttaaggctg gacaaacatt gattcaattt gatatagcag
    34681 caatttctga agctggatac gccactgaaa cgcctcttgt ggtgactaat caagatgttt
    34741 ttacggtaac tgttgaaggt agtttaccgc gtcagattaa ggttaatgat aagttagcag
    34801 tagcggtgaa aaagtaggtt tactaagaga aaacgttcag gaactgagat cagttcctga
    34861 aactatttta gggaggaaaa ctcatgacaa ttgataaaaa gaaagtcgtc tatcaaattt
    34921 acccaaaatc ctataaggac acgactggaa atggtgtggg agacttgcta gggatcattg
    34981 ataaattgcc ttacttacaa gaactaggaa tagatatgat ttggttgaac cctttctacc
    35041 ctagtccaca acgagacaat ggctatgatg tttcagatta tacggcggtc aaccctgatt
    35101 ttggaacaat ggctgatttt gaaaatttgg taaaagctgc taaggagcat cagattgagt
    35161 taatgttgga catggttttg aatcactgtt ccacagacca cgagtggttc caaaaagctt
    35221 tagcaggaga cccttattat caggatttct ttatcttgag agatcagccg actgattggg
    35281 tttccaaatt tggtgggaat gcttgggcgc cttttggaga tacaggcaaa tactacttac
    35341 acttgtttga tgtgacacag gctgacttga attggcggaa cccacatgtt cgtgaggaat
    35401 tggctaaagt ggttaatttt tggcgagata aaggagtgaa ggggttccgt tttgatgtga
    35461 ttaacctgat tgggaaagat gaagagctgg tggattgtcc ggtcaatgat ggtaagccag
    35521 cttatacgga tcgtcctatt actcacactt atcttcatga tctcaatcaa gccagttttg
    35581 gtcaggatga ttcgtttatg acagtagggg aaatgtctgc aacgactatt gacaactgtc
    35641 ttttatacac ggctcccgaa cgtgaggagc tatccatggc ttttaatttc caccatctaa
    35701 aagttgatta tgagaacggt cagaaatgga ctattatggc ttttgatttt gcagcgctgc
    35761 gagacttatt ccatgcttgg ggtgaaggca tgagtcaggg caatgggtgg aatgccttgt
    35821 tctacaataa ccatgatcaa ccacgtgccc tgaatcgttt tgttgatgta acacatttcc
    35881 gaaacgaagg tgcgacgatg ttagcagctt ccatccattt gtcacgagga acgccttaca
    35941 tttatatggg tgaggagatt ggcatgcttg atccagactt tgatagtatg gatgattatg
    36001 tggatgtgga aagtctcaat gcttactcaa gcttattagt ctcaggtaaa agtgcagaag
    36061 aagcctttgc cattatcaag gccaagtcaa gggacaatgc cagaacacca atgcaatggg
    36121 atgctagtga acatgctggc tttacgactg gtaagccttg gttagaggtt ggcaaatctt
    36181 atcgagacat caatgtcgaa acagaaaaag agggacgtat ttttcctttc taccaacgct
    36241 tgattgcttt gcggaaggaa ctccctatta ttgctgaagg ggactatcgg gctgctttta
    36301 aagatagtca ggctgtctat gcctttgaac gccatttagg tgaccagtgt ttgcttgttc
    36361 tcaatcattt ctatgctgat gaggtcgaac tggaattacc tccacgttat caacatggac
    36421 aggtcttaat cagcaactat gagaaagttt ctatttgtga aaaagtgata ctgaaacctt
    36481 atcagacact tgctatctta gctgataact aactaaaagc ctgaggttag gcctcaggct
    36541 tttgctgatt gtcacgaaaa aagaagtttt ctcatatatt tatttttaaa ctcttatttt
    36601 ttctaaataa aaacaattga gataagttat tttagctaaa ttttggtaca atggaaaaga
    36661 ttataagtag agtttaagat aaagattcta caaatttaaa atgatataag gagatacgaa
    36721 tgacaactta tcaagatgat ttttaccagg ctgtgaatgg aaagtgggct gaaacagcag
    36781 ttattccaga cgacaagcct cgaacaggtg gattttcaga cttagcagat gaaattgagg
    36841 cattaatgct agacactaca gatgcttggc tagctggaga aaatatccct gatgatgcta
    36901 ttttaaaaaa ttttgtgaaa ttccatcgtt tggtggctga ctacgctaaa cgtgatgaag
    36961 ttggagtaag tccaattctc cctttaattg aagaatatca gtccttaaaa tctttttcag
    37021 aatttgttgc taatatagcg aaatatgaat tggcaggttt accaaatgaa tttcccttta
    37081 gtgtggcacc agactttatg aatgctcagc tgaatgtgct ttgggcagaa gcaccaagca
    37141 ttcttttgcc agatacaaca tactacgaag aaggcaacga aaaagctgag gaattgcgtg
    37201 gtatttggcg tcagtcgcaa gaaaagcttt tacctcaatt tggtttttca acagaagaaa
    37261 tcaaggatct tttggataag gtaattgagc tagataagca attggccaag tatgtcttgt
    37321 ctcgtgagga aggctcagaa tatgccaaat tataccatcc ttatgtgtgg gctgatttta
    37381 aaaaactagc tccagagctt cctttggata gcatttttga aaagatttta ggccaagtac
    37441 ctgacaaggt tattgttcct gaggaacgtt tttggacaga atttgcagcc acttattact
    37501 ctgaagccaa ttgggattta ctcaaggcta atttgattgt ggacgcggct aatgcttaca
    37561 atgcttactt gacggatgat attcgtgtgg aatcaggcgc ttattcgcgc gctctttcag
    37621 gaacacctca agctatggac aaacaaaaag cagcctttta tttggcgcaa ggaccgttta
    37681 gccaagcgct tggcttgtgg tatgctggtc aaaaattctc cccagaagct aaggctgatg
    37741 tggaaagtaa ggtagcacgc atgattgagg tttataagtc tcgtctagaa acggctgatt
    37801 ggttagcacc agccacacgt gaaaaagcca ttactaaatt aaatgttatc acgccacata
    37861 ttggttaccc agaaaaatta ccagaaacct atgctaaaaa agtgattgat gagagcttgt
    37921 cattggttga aaatgcacag aacttggcta aaatcacgat tgctcacact tggagtaaat
    37981 ggaacaagcc agttgaccgt agtgaatggc atatgccagc ccacttagtc aatgcttatt
    38041 atgatcctca gcaaaatcag attgtctttc ctgcggcaat cttacaagag ccattttatt
    38101 ctttagatca gagttcttca gccaattatg gaggaattgg tgcagtcatt gcgcatgaga
    38161 tttcacatgc ctttgacacc aatggtgctt cctttgatga acatggtagc ctaaatgatt
    38221 ggtggacaca agaagactat gctgccttta aagagcgcac agataagatt gtggcgcagt
    38281 ttgacggctt agagtcacat ggtgctaagg tcaatggtaa attgacagtt tcagaaaacg
    38341 tcgctgatct aggtggggta gcttgtgctt tagaagcggc acaatcagaa gaagacttct
    38401 cagcccgtga cttctttatt aactttgcga cgatttggcg tatgaaggcc cgtgaggaat
    38461 acatgcaaat gctagctagc attgatgttc atgctccggg tgaactgcga acaaatgtca
    38521 ccttaaccaa ctttgatgct ttccatgaga cctttgatat taaagaaggc gatgctatgt
    38581 ggagagctcc gaaagaccgt gtgattattt ggtaattagg tagttgataa accttcaaat
    38641 gcctgtgatt ataaaaatga ctgattctgt gaaacacagg atcagttttt tgcttcctta
    38701 ttggtgtccg ttttgacaca acaaaaagac aaccctcagg aaagaaggtt gcctttttta
    38761 gacttatcag aaataagtga ttagttgtta agggcagcag ccatagtagc tgcaacttct
    38821 gattcaaagt cgttagcttt tttctcgata ccttcaccaa cttcaaaacg tgcaaaagca
    38881 atcgctttag cgtttactga gtcaaggtaa gcttcaacag ttttgctgtc gtccatgatg
    38941 taaacttgtg caagaagagt gtaagcttgg tcaactttag tgttgtcaag catgaagcgg
    39001 tccattttac ctgggatgat tttgtcccag atcttttctg gtttgccttc agcagcaagt
    39061 tcagctttga tgtctgcttc agcagcagta atcacatcgt ctgataattg agcttttgaa
    39121 ccgtatttca agaatggaag agctggttta tcaaccattg cacgagattc gttgtcaagt
    39181 tcgatagcgt ggttcaattg agcaagttca tctttgatga attgtgcatc aagctcagtg
    39241 tatgaaagaa cagttggttt cattgcagcg atatgcattg atacttgttt agcaagagca
    39301 tcgtcgccgc cttcgacaac tgagataacc ccgatacggc caccattatg ttggtaagca
    39361 ccgaagtgtt gctcatctgc tttttcaatc aaagcaaaac gacggaatga gattttttct
    39421 ccgatggtag cagttgcatt aacgtaagct tcagcaagag tttcacctga aggcataaca
    39481 agtgcaagtg cttcatcgtt gttagctggt ttgccttcag cgataacttt agcagttgcg
    39541 tttaccaatt caacgaattg agcattttta gcaacaaagt ctgtttcagc gttaacttca
    39601 acaacagcag caacgttacc atgaacgtaa acgcctgtta aaccttcagc ggcaacacgg
    39661 tcagcttttt tagctgcttt agccattcct ttttcacgaa gaagttcaac ggctttgtcc
    39721 atgtcaccat ctgtttcaac aagtgctttt ttagcgtcca taacgccagc accagatttt
    39781 tcacgtaatt cttttacaag cttagctgta atttctgcca tgtgtagtat cctccaaatg
    39841 atatttgttt tggtttcaaa aaacgagaca gagcggtttg ctttctgccc cgtttggttt
    39901 tcgattgtta aagacaaaca aagtttgcta taagagttag gaactctgtg ctaattaagc
    39961 gttgtcgcct tcgacaactt caacgatttc ttcgattgaa tctgcttgag tgtcagcttc
    40021 aaaagcaacg tctgcatctt caccttgacg gccttcgata atagcgtcag ctaatttagc
    40081 agtgattaat ttaacggcgc ggatagcgtc atcgttagct ggaatgatga tatcgatatc
    40141 atctggatca gcgtttgtat caaccatcgc tacgactggg ataccaagtt ttttagcttc
    40201 tttaacagcg atttgttctt tatgtgggtc aacaacgtac attacgtctg ggatacgagg
    40261 catatcttcg ataccgccca agaatttttc aagacgagcg cgttgtttgt taagaagtgc
    40321 aacttctttc ttaggaagaa cgtcaaaggt tccttcttct tccatacgtt tgatttcttt
    40381 caaacgagcg atacgttttt ggatagttcc ccagttggta agcgttccac ccaaccaacg
    40441 gtggttgatg aagtattggc ctgcacgcgt tgcttcgtca gcaactgctt cagcagcttg
    40501 ttttttagta ccaacgaaca agatgacagc atcgtttgct gcagcatcac gaacaaattc
    40561 gtaagcttgg tcagctaatt ttacagtttg ttgaagatcg ataacgtgga taccgttacg
    40621 ctctgtgaag atgtatttag ccatcttagg gttccagcga cgagtttggt gaccaaagtg
    40681 aacaccagcc tcaagaagtt gtttcattga aattactgcc atgagtagtt tctcctttat
    40741 aaaatgtttt ttcctcttcc agacttcgac ttgcaggcta acctatcggc aacaagccca
    40801 caattggtct agaatgagta tttgccgtct acacgacctt actatagtat caaaaaaaga
    40861 ggttaaaagc aaggagaaat gctatggatt cccttatttt tgagatgact agcttctttg
    40921 tttattggta agtgttaaga caagcttttg ctcattttgg gtgacacttg ccaaatcgtt
    40981 ttatttaaga tatagtgaat ttgactaatt tttggaggcg ttttcatgac gaagggtatt
    41041 cgatttcaat tgcttggcag tccccacatt tttcttgatg acaaagaaca attttttgcc
    41101 tttgccaaag caaatgctct cctttattac ttagtggtta atggatctgt tagccgcgag
    41161 gtggcggcga gtctactttg ggaaaataag aacacgcaaa cagcgaaaaa gaatttacga
    41221 aacgctatct accaggtcaa taaagtcttg caagctgatg tgattatttg tcccaatcgc
    41281 aacctgctgg ttttgaataa aacacttgat atcaaaacag atattaacct ttttctggct
    41341 gatccgctag ctcacttaga actctaccaa ggggagtttt tgcagggctt ttaccttaaa
    41401 agtggtgagg aatttgatct ttgggtttca aaaatgcgta tgcagtatga acaggtatac
    41461 ctaaaagcgt gttaccaaaa aattgaagaa aagctctctt tagatgccat tgaagatgtc
    41521 gaggaacatt taaaacagct tattgaacgt gatgaatttg aagagaaaaa ttatcagctc
    41581 ttgatgaggc tttatcagca ggggaattgt cctggtaagg tcatcgaaac ttattatcag
    41641 ttggctaatg tgttggataa ggagctaggg attcagccaa gtttgcaaag ccaacagatt
    41701 tatcaggaag tggtcgctaa agatcgtaat gaacgcaaaa tcaagcattt tttgcgcaac
    41761 agtaatcatt ttttggggcg gattgatgag attaagcagc tggaaaacta ttttgccaac
    41821 tgtttggcct gccaagaggt aggagctctg ctcttaattg gtgatacagg gattgggaaa
    41881 cgaaccctag ccagacaggt cttagccaat caaacccaaa cgtttcaaat tgtcacagct
    41941 aaatgttttc gtgaagaggc tatggattcc ttattgcctt ggcgtaatat cttagatggc
    42001 ctgggagatt tggtgattca aaaccgctta ttgaccacca aagcttggaa ggctgctctt
    42061 aaacgctgtt ttcctgtggc aaccattttt caagaagata acaaccaacc ctttatcaag
    42121 gaccacacca gcttgttggt ttcctttatt gttgatattt tacaacattt ggcagaaatc
    42181 aaggcgctgg taatccttat tgaggattgt cactggatgg atgaggatag tttgaccttg
    42241 ttgcaacggg tcatgaatca attggtccac tatccgattg cttttgtctt gaccaagcat
    42301 ctaggaacga ctcctgagct cggtctttgt ttgaatgctt tgatgagtca agggcgttta
    42361 gaaagcattt gtttggagcc ttttaatcgg caagaaagtt tggtttatat taacagtcaa
    42421 ctgggtagtc agccagtgac ggcagaagaa atggagcacc tctatcaagc cagccaaggc
    42481 aaccctttct ttttgtcaga atacactcag gccctactgc gtcacgaaaa atttgtgcct
    42541 ttaacgcctg ccattaaggc taagttgggt cttaaactag ctaatctaag tagtcgtgat
    42601 gacgcattgt taaactattt gtcttgttgt cggaggccta tccctctaaa taccctcgct
    42661 caattgatgt tactgccttt agaagaagtg atcgagatgg tggataatct ggggcactac
    42721 tatattttgg tagaagaaag cgtaggagag gaagtgttga tttcatttcg tcagcggatt
    42781 attcaactct atagttatga ccgtttatct ttgtcaaaaa ggcgtttatt gcacggacaa
    42841 attgccaaac ggttagaaga tttactgcct attttgacac caagccctca cttattagat
    42901 gacattgctt accattatca ggaatcacgg caggtgatta aggctttgga atacaacctt
    42961 aactatctag atgctacctt gccatttcag catgagctgt ttcccattta ttcaaagagt
    43021 attggctcct tggaaaagtc agatcgtgac catcaacgct taatggaaga gcagtttgat
    43081 aagattcgtc aaagcattgc ggatttggaa ctgacctatg ataataaccg tgatttccag
    43141 cagttgctta ttcgtttttc ttaccttgaa ggccgttatg atattcgaac agggaggtat
    43201 caagaaggga ttaaacacat tcaaaaggtc atcgctttgg caaccgagct aaaacagccc
    43261 tccttcttgc tagaaggcta tcgccagtta attcattact gtatccaagt ggaaaacaag
    43321 ccagaaatgc gttattacac tagtctttca ttggaggcag cggttgctgc taatcatttt
    43381 gaggccattg cgattagttt gcggttaaac ggtctctatc atttgattat tggggagtta
    43441 aatgaggcag agcgtctgct tcaacagtcg attgacttct tcaaggtgac gccaggcttg
    43501 caagctaact atgcgattca gattgctgct gccttagatt atttggggga gattgcccag
    43561 attcgctatc agtttgaaaa ggccgttgct tatcaaaaac aagccattgc cttgaccgaa
    43621 aacaagccag ctgagttatc ggcgagtatt ttttatattg gattagggat ttcctacttt
    43681 tatttagctg attttgaaca agctgagcaa atcttgagtt tggctaagga agctttggtc
    43741 aatcatagtt atccttggaa agaaacgcaa cttgaaattt acctggctat gattcaatgg
    43801 aaaaagggca attatcagcc agccttgacc ctacttgatt acagagaaac cttgatgtct
    43861 aggtatcgca atccgcgtga taagggcttg gttttctatt tgatggctgt ggtcaagtac
    43921 caattgatat ttcaaggagc taccctaagt cagcaggaaa aagaaatggc agaccacctg
    43981 ttgtcagaat cctttgagta ttattatgag attgctagta ctaacctcaa cccttaccga
    44041 gattgtcatt tggtgagtga gttgaacgat ttgcgtcaac aattatctgc taaaagctaa
    44101 ggaaaaccct ctgaagtgaa tcagagggtt ttagctatgt tgtgccataa tctgtacgag
    44161 gtaaaagata aaggtggctg ctaaattggc ggtgtggtta tcaatatcgt gtggtggtga
    44221 aacctcaacc acatcaaagc caactaattt tccgctagct gcaatgtgtt gcaaaactaa
    44281 gacggcaaga tttgggtcaa caccgaggga ctggatagca ctaaccccag gcgcagcacc
    44341 aactgagaaa caatccatgt caatggtcag gtagaccctt tcttgccctt ctaagaaacg
    44401 gtcaatggct cggcagacct tttgatggcc catttggtag atgtcttgac ctgttaaaaa
    44461 ttgaatgccc ttggattttg ccacaaagtc aaataggaaa aggttgttat tatgttcttg
    44521 aatgcctaaa acgaagtatt taaagaggcg tttgtcagca accgcatcgt caaacatctg
    44581 tcgaaagcct gtccctgaat tagggcctgt ttggtcgtaa ggccttaaat caaagtgggc
    44641 gtccatattg atgacagcta ggtcatcact tggggatagg ctttggcgta ggcctaagta
    44701 gtggccgtag gcggtttcat ggccacctcc taagacgatg ggtttgagat tgaggtcaca
    44761 catccgtttg atggctttgc ttaaactgtt ttgcagttgt tccaaagagc gattggggcc
    44821 gtcaatgtta cccacatcgt aaaccataac ttggtttcct aaatgccaag ggaatttggc
    44881 gagctgggtt cgtatggcag ctggactttc gaccgctccg acacgaccat tattgatata
    44941 aaccccctta tcacttttaa agccaatcaa ggcaaaatgt gtcccttcaa atggggttag
    45001 tgagctgtcg ttaaggtcaa ggaaagtcat gaccatgccc catttggcag tatataagtc
    45061 atcgtcgatc ccaccatgat aatagctagt ggtggatggg tagtaatctt ctagcatgcg
    45121 cgtcatctcc tttaggatta tgatagcaaa ataaaactta cagtcaacac tttcttggcc
    45181 tttgtcactg gtttttagga atagcagagc aataaaatcg tctgcttttg gtcccggtta
    45241 gttagtctaa agaggccatg acctctgcca cagcccctct agttaaagaa gtaccttatt
    45301 cactaaaatt ggatactcaa ctcaactgcc tgctcaaccg cttcgaggaa gcttgggtct
    45361 tcaatgactg ctgatgcctt gtttagttca tcgtagattt cgatgtgttt atcgtgttcg
    45421 ataaagttga cttccttgcg gaagagatcg taggcaacct tagtcccttt acctagttca
    45481 tgattttcag gtttgagatc aagggcttgg caggctgcca tgatttcagt agccacgatg
    45541 cggcgagaat ttttaaggat ttcaaaggcc ttgcgagcag cggtggtgcc catgctgaca
    45601 aagtcttctt ggttctcaca agatgggata gaatccacac tggctggatg tgccaaaacc
    45661 ttgttttcag aagcaagaga ggcacaggcg tactgggtaa tcataaagcc tgaattgaga
    45721 cctgggtatt tgacaaggaa ggatggcaat ttgctgagct ggctattgac caaacgttcc
    45781 acgcggcgtt cagaaacatt tccaatttca gaaatggcga tgcctaagaa gtcaaatggc
    45841 tgtgccattg gttctccgtg gaagttacct cctgaaataa cgtggccatc tttacagata
    45901 attggattat ctgtgacaga attgatttca atgtcaactt tggatttgac ataggcgata
    45961 ctgtctttgc tagccccatg aatttgaggc atgcagcgca aggtgtaagg gtcttgcaca
    46021 cgagattgag tagctacggt tgtgttttgg ctgccttcaa ggaggtttcg gatattgcgg
    46081 gctgttgcca actggccgct ttgtgggcga atggtgtgaa ggttttcttc aaatggacta
    46141 gtaatcccgt tatgcacttc aagggatagg gcaccagcta ggtctgacag tttcaataat
    46201 tgaatggcgt cataggttgc aagggcaccg actgcagtga gaacagttgt tccgttgata
    46261 agggcgagtc cttctttagc ggctaaagaa atcttgtcaa taccagcttt atcaagagct
    46321 tcttgaccag aaagaagctc tcctttgtag taagctttcc ctagaccaag cataggaagc
    46381 accatgtgag caagcggcgc caaatctcct gaagccccta gagacccttt ttcaggaatg
    46441 taaggatgaa cccctttatt gagcagttcc aacagttttt caatggtgga tagacgaata
    46501 ccagaatacc ctttgactag tgaattgata cggatcagca tgatagctct cacggcatct
    46561 tctggcaatg ggtcaccaaa tccactagca tgggtacgaa tcaaattttc ttggagttga
    46621 actgtatctt ctggtgagat gctcacgtta caaagggatc caaaaccggt ggtcaccccg
    46681 taaaccaccc gtttttcact gacaatgtca tcaacaattt tacgagaggc attcacagct
    46741 tcaatagcac tatcatcaat gtgacaggct acgccttggc gagcaatcgc aatcacgtct
    46801 tcgatagtaa ggctttcgcc atctaaatta atcactcttg tcatagtttt tctcctagat
    46861 ttgttcctta gggggcattt ggtccatttg gtggttacgt ccgtgcataa ggtagtacac
    46921 actacttgca atgatgacac caactgcacc ataaacaaag ttcattgggt tgtcacccca
    46981 aatcataact aaactaacga taactgcaag aattgggata atagggccaa atggtactcg
    47041 gaagatcaca ttagcatcgg gatcgtcctt ccgtaatttc ataacggcta gtgctgttgg
    47101 aatgtattgg aagaagcgga aaacaacact gagttttgct aagctttcaa atgagccagt
    47161 aagcaggagt acaatggcaa ttgctcctga aaccaagata gcaacgagtg gcgcgccatt
    47221 ttgattttgc ttggcaatag cagctggtaa gagcccttca tcagcaatgg cagcaccgta
    47281 acgtggcacc atgatggatt ctcccatgtt aagacctgta atggaaatta aagcaccgat
    47341 tgagaccatc caagcgccag cagggcctat cattttaaca aaggcatctt gaacaggtgc
    47401 attggtcatc atgatttgag agccaagcat ggcaatggtt ccaccgataa tcagcatata
    47461 taagacagag acgatactga ttgatcctaa aagagcacgc ggtacatttt tttcagggtc
    47521 acgcatttcc ccagcgacaa tagagagggt ttcaaaaccg ataaagccat agaagatata
    47581 aacagcagta ttggagatag cccctaagag gttagtccct ggttccaact gaacaaatgg
    47641 ggtaaagtta ggaagcccgt ttttgatgaa gaaaagggta caggcacaaa aggcaacgat
    47701 tggaattaac ttagcaatgg tggctgtgat ggtgacaatt ttagaggttt tcaaaccagc
    47761 gatattcatc aaagatagta agatgattaa cccaatacta agtggaatgt gccaaccttc
    47821 aaaggcaggg aaagtaatga taaacattct ggcaaaccca gctgccatgg ctgcccaagc
    47881 gaagatggta acggtccaac caaggaagcc aacgttaaag ccaataaaat caccaaaagc
    47941 tcgtttggaa tattggaagg ctccgccgtt tttcccaaaa taaccagaga cttctgcaaa
    48001 acaaactgcc aacatgatgg tcaaaatagc tgttccaaac ataacagcga tggatgcagg
    48061 gccaaggccc ttataaatgg ccctaggtaa gagaaaaata ccagagccga taacggcatt
    48121 gatcccgtaa agagtggcac cgctcaagct aaactttgcc tgttctcttt cttgttcgtt
    48181 catgtgattt gacgccataa taatgctctc ctttttgttt gcaaattgcg ttcaaatata
    48241 atggataagg tcgctaggaa atgaggagat agtcggttta ggaggatcct tcttgcacct
    48301 aacgatagtg atgagctatt ggttagcgat gagaaatagg tagccttttg taatgatgtg
    48361 tagtgatttc attggagaag aataggcatg agtagtgtga tgcctatctt tatcccacta
    48421 agtcttatac cataagcctg cccaaacagc tactggagtt tgggcggggc ttgtttgatt
    48481 gaggcaaact tttagatctg aaaggctggc ctcctgctcg gttaccaaca agtgattggc
    48541 ttcaagctct tgattcgcct gattggtcac agaataagtc agtttgctta gggcataaag
    48601 cagttgacag tccgctttag gtgcctcaaa tggtgtgtca gaccagacgg gtaataattg
    48661 cccttggtat tggtcatcat acattaaatt gatgtcttgg caggttccac gactgacgat
    48721 tctggtatcg ccttcaaacg catagggttg aaaaggagct agggaaatct ctttagcatg
    48781 actcaaatca cttaatgtga tgggcttgtc taggctcatt agaatcctgt gatagccatc
    48841 aagtcgggta aaggttgtct gtcgtagggc tacagttgca gttgagagac gataagagaa
    48901 ttctctcttt ttgtaatctc catcttcggg ataaaggaac aattggttgg tttcaccgcc
    48961 agaccagtca gtttggaggt aatcagaggg cgctttgatg gttacctttg tcatttgttc
    49021 tctccttatt tccaattaga atagtcctgt gatgttgccc tcctcgtcaa tatcaattgt
    49081 ttcgctggca ggtacttttg gaaggccagg catggtcatg atagcacctg ttagggcaac
    49141 gataaatcct gctcctgcgg acactttaag gttgctaata gtcactgtaa agtcagttgg
    49201 tgcgccaagt tttttggcat cgtctgagaa ggaatattgg gttttggcca tgcaaattgg
    49261 gtagttgcca aagccgaggc gttctaagtc agccagttca cgtttggctg ctgagctcaa
    49321 gttgatgcct ttaccaccgt aaactttggt aacgatttta gtcagtttgg tttcaatgct
    49381 atcgtcttcc tcataaacaa agcggaattg attgtcttgc tcggctagtg tcacgacttt
    49441 ttcagccagt tcacggccac cagctccgcc atttgcccaa acatcagaaa tcacaacgtc
    49501 aacgccacgt ttgtcgcagg catcatagac agcttgtaat tcggcatcgg tatcaagcgg
    49561 gaatttattg atcgccacga caactggaag gccatagacg tcttggatat tagccaaatg
    49621 tttgtcaagg ttaggtaaac catccacaac ggcctgaaca ttttcagtag ccaggtctgc
    49681 ttttggcaca cccccatgca ttttaagggc acgtatagtg gctactagga caacggctgc
    49741 tgggcgaagg cctgacatgc ggcatttgat gtcaatgaat ttttcagctc caaggtcagc
    49801 gccaaatcca gcttcggtaa cggcataatc accatatttc aaggctagtt tggtggcgag
    49861 gacactatta cagccatggg cgatattagc aaatgggcca ccgtgaatga gggctggtgt
    49921 gtgttccagg gtttgcacga gattaggatg aatcgcatcc ttgagcagag cggctagggc
    49981 accaccagct ttcaagtctt tagctgttac aggttcacct tggtagttgt aaccgatgat
    50041 gattttttca aggcgggctt tgaggtcaga aatattttcg gataggcaca ggattgccat
    50101 gatttcagag gcgacggtaa tgtcataacc atcttcacga ggaatcccgt tgaccttgcc
    50161 ttgcaagccg tcaacaatat gacgaagctg gcggtcattc atatccacca cacgtttcca
    50221 agtgatacgt ctggaatcaa tgcctaggct attgccatgg tgaatgtggt tatcaatcaa
    50281 ggcagctaat aagttgttgg cgacaccgat ggcatgaaag tcccctgtaa agtgaaggtt
    50341 gatgtcttcc attgggacaa cttgcgcgtg gccaccgcca gcagctcctc ccttaacccc
    50401 aaaaacagga ccaagagaag gttcacgaag ggcaataact gctttttttc caatggcaga
    50461 aagagcatct accaatccaa cagaagtggt ggttttgcct tcaccagctg gtgttggtga
    50521 gatagcagtg acaagaatga gtttgccatc aggtttgttt tttaaggcga ccagttgacg
    50581 ggcatcaatt tttgccttgt acttaccata gagacagagc gcctccttgt caatccctaa
    50641 ttgatcggca accttactga taggttccat agtgacagag ttggctattt caatatctga
    50701 taaaaccata gttgctcctt tacttgttaa acaatatcga gaattttcgt gtagatgtca
    50761 tctgccaaat gacagccctt gtctagtaag gcttgtcctt tttggcgata gtcggtaaca
    50821 aagtcttcat ctttgatgcc agacagatta atcaaaacat tcaaccaagc gccttgtaaa
    50881 cctgctttta agtttaaagc agcaactcct aagtcgctag cagcatttgt attagactta
    50941 ccgacagctg ttgcagtgat ctcaagtgct tcgaccatga gggtcatcat ctcaaaaggt
    51001 gattgtgcag ctgttttcaa ggccttttgc atggcagttc gtctagcagc cttgtcttcg
    51061 tcagtctctt ttggcatatc aaaaacggca gaaaccaggt tgaaggcttc ggtatctttg
    51121 tcaatggctg caagcaagct agcttgtaga gcggtgcttt tagcatggat ctctgtaata
    51181 atatcttggt agtcagcgta ttttttctta ccaagagtca attcacagac catcttggtt
    51241 aaggaaatgc cattagcgcc agagagagca gcagcagaac caccacctgg agcaggggca
    51301 tctgagccaa ggactttagc gaaatctgtt aagcttaaat caactaaacc catagagaac
    51361 ctcctaacct agcaaatggt tttcaagaat ctgtttatgg tagtcaaagt cctcaacttg
    51421 taagtagtat tcagccacat cgattaaggc cttggctggc gctaagccga tgacttcaga
    51481 accaataaca ttcacaccgt agcgacgcgc ttcaaatttg atggtttcaa aagtacggta
    51541 aagagaacat ttttcaaagt taaccatgtt catggaaact tgggcaatat gacggtcttc
    51601 taacatgaca ccgatagcct tacaatattt gtagccacca cctgaaccgc ggataatttt
    51661 cgcaatttta tgagcaatgt cgatattgtc agtatccaaa ttaacattga aagcaaccaa
    51721 tggcatgcga gcaccaacgg cagttacccc agcagttggg tgaatcttac gatctccgta
    51781 gtcaggtgcc caatcctctt ccaacagttt ttctggcatg ccttcgaatt gtcctttacg
    51841 gactttggcc aggttttgac gttctgggcg tgtggcagaa tcttcataaa ggaagattgg
    51901 gattccaagt tcacggttaa tccgttctgc gacttgtttg gaaatctcaa cacattcttg
    51961 tgtagtgatg tctttgatcg gaacgaatgg gcagacatcg gttgctccca tacgagggtg
    52021 ttcgccatga tgtttggtca tatcaatgtt ttcagaagcg tatttcacca gttggaaagc
    52081 tgcttcttga atagactggt catctccaac caaggtaaac acgctccggt tgtggctcgc
    52141 atcagaagag tagtcgagaa gggtcactcc aggaatactt ttggccgtcg ctaccaaacc
    52201 atcgataaca gcctgatttt ggccttctga gaagttggga atacattcaa caattttcgc
    52261 catgtttaat ctccttttat gtcattgaat tactcattaa gggaataggt tatctacttt
    52321 agataacgct tacattttta gctagcagtt attagtgaaa taattgatct actgctgaag
    52381 tcacaaggtc atcatcagcc aagtatggga tagtgatgtg atcagtacct gcatggagac
    52441 gattatactc aatagcggtt tcaatagcgt gctcattgcg agcccaattg cgacgagcaa
    52501 caccacccat ggtgtcccaa gcaatagcag atttaataat ctcatcaatg cgttcgctgc
    52561 catctaaaac aagtccgaaa ccaccattga tggctttacc aataccagtt ccgccaccgt
    52621 tatgaagagc cactaaactc ataccacgcg cagcgttacc agcgtaacat tgcaccgcca
    52681 tatcacaggt cacattggaa ccgtctttaa tgtttgaggt ttcacgaaat ggtgagtcgg
    52741 taccagacac gtcatggtgg tcacgaccaa tcatgacagg accaatcttg cctttgcgga
    52801 ccaattcatt aaatttaagg gcgatagtca cacgaccgat acagtcttgg taaaggatcc
    52861 gggcttgggt accaactacg agttgatttt tctcagcatc acgaatccag ttgtagttat
    52921 cacggtcttg atagcggcgg tcaggatcga tagcttccat ggcagctttg tcagtggcca
    52981 ccaagtcatc gtgattacca ctcaagcaga cccaacggaa aggtccatag ccatagtcaa
    53041 aaagcatagg tcccatgata tcttccacat aggatggcca gataaatccg tctttgtcgt
    53101 tacgaccatt cttagaaatt tctgtaatac cagagtcgta aacagacttc ataaaggcat
    53161 tgccgtagtc aaagaaatag gtgccatttt cagttaacgt cttaatagct tcaaaatgcc
    53221 gtgccaaggt atcatcaacc atttggtgga aggtatcttt atcttctgcc aagagccggg
    53281 ttctttcgtc aaagctaata cctactgggc agtagccacc gtcataaacg ttgtgacaag
    53341 aggtttggtc agacaaaaga tcaacatgaa tctgcttgtc attgacgtac tctaaaagat
    53401 caacgatatt accatggtaa gcaatcgaag tggactcctt agcatctatg gctttttggg
    53461 ctaattgcag agcttcttca gggctttcgg caatttgact gatccagcct tgagaatgac
    53521 gggttttaat ccgagattgg tcaacttcag caataatggc aactgcttta gcaatttcag
    53581 cagccttacc ttgtgcccca ctcatgcctc ctagaccaga tgagatgaag agtttaccgg
    53641 tcaaatcacc gtcatcagcc actccaagtt tgagacgacc agcatttaag agggtattaa
    53701 acgttccatg aacgattcct tgtgggccaa tatacatcca accacctgcg gtcatttgac
    53761 catagttggt gacacccatc tcttcagcga tttcccagtc tttcatgttg tcgtattcac
    53821 ccaccaaaag gccattagta ataatcacac gaggcgcttc aggtttggat ttgaaaagac
    53881 caactggatg accagactca accaccaagg tttgttcatc agtcatgact tctaggtatt
    53941 ttttaatcaa acaatattgc atccagttgg cacaaacaga accagtttct ccatatgtga
    54001 ctagttcgta agggtacaag gcaatttcaa aactcaagtt attgtcaatc atgacctgca
    54061 tggccttggc agctgtacaa tttcccttgt actcgtcaat gggtttgccg taaatgcggt
    54121 cttttggtct aaagcggtag ccataaatac ggccacgggt tttgagttct tccaaaaatt
    54181 ctggaatgac ttcttcgtgg aacttcgtag gtacatagcg tagggcattt ttcaaggcga
    54241 tttcggtctg agcctgggtc aatcgaaaac ctctgtctgg tgctcttcgg ataccttctt
    54301 caaacacagt cttttccggt aaaacatcgt ctaacttaac agtcatagcg gcagctatgt
    54361 cagtttcact gtaaaatgac atagaaaact cctcctcaac tcctttttat tgtcgagatt
    54421 agtctaactt agtctagtct ataaaaagtc aaccacgctt tgaaatgcga aaaaagtcta
    54481 aaaaaaaatc aaaacctcat tttttgacta aaatttgacg cttaatcagt acacttgagg
    54541 tatgacagat aaagtcagtc agaggttaat tgttgttacc aaagttgcaa agatcgcaac
    54601 tattgagtgg gtgagggggg actagtaatg gctattaatc agttgacaaa cgatgttaaa
    54661 aaaggaggtt tttatggttg ctgatgtctt attaacacat tttaatcaac tattttgtct
    54721 aaatgatcca ggtcatcctt taactggtca agaaatgaaa aaagccacta tcgttgaaga
    54781 tggctatata gccatcaaag acggcctcat tgtggctctt ggttctggtg aaccagatgc
    54841 tgagcttgtc ggtacacaga ctattatgcg ttcttataaa ggtaaaattg caacgcctgg
    54901 tattattgac tgtcataccc atttggtcta tggtggcagt cgtgaacatg aatttgccaa
    54961 gaaattagca ggggtgtctt acttggatat tttagctcaa ggtggtggta ttttaagcac
    55021 ggtgagggcc actcggtcag ccagctttga caacctttat caaaaatcca agagattgct
    55081 agactacatg ttgcttcatg gagtgactac tgtcgaagcg aaaagtggct acggccttga
    55141 ttgggaaaca gaaaaacgcc aactggatgt tgttgctgct ttagaaaaag accatcccat
    55201 tgatttggtg tctacgttta tggcagccca tgcgattcct gaagaataca aagggaatcc
    55261 taaggcttat ctcgatgtga ttatcaagga tatgcttcct gttgttaaag aggaaaatct
    55321 ggcagaattt tgtgatattt tctgtgaaaa aaatgttttt acagctgatg agtctcgcta
    55381 tctgttaagc aaagccaaag aaatgggctt caagcttcgt attcacgcag atgaaattgc
    55441 gtctataggc ggagttgatg tcgcagcaga gctcagcgca gttagtgcag agcatttgat
    55501 gatgataaca gatgatggta tcgctaagtt gattggtgct ggtgttattg gtaatttgct
    55561 tccagccacc acctttagtt tgatggaaga cacttatgcc cctgctcgca aaatgatcga
    55621 tgctggcatg gccatcaccc tctcaacaga tagtaatcca ggcagttgcc cgactgctaa
    55681 catgcagttt gtgatgcaat taggttgttt tatgttacgt ttaacaccga ttgaagtctt
    55741 aaatgctgtt accattaacg cggcctactc tgtcaatcgt caggagagag ttggtagttt
    55801 gacagttggt aaagaagcag atattgccat ttttgatgcc ccaaatattg attacccatt
    55861 ttatttcttt gccaccaact tgattcacca agtctataaa aaaggacaac tcacagttga
    55921 ccgaggtcgt attctttaaa aaatttaaaa aagaagcttt gagcgttagc tcaaaacttc
    55981 ttttaaatat gctgttttat tgacgaatca agtagtcaaa ggcaccgatg gcagcagtag
    56041 caccagaccc catggaaata atgatttgtt tataagctga atcagtacag tccccagcag
    56101 caaagatacc aggaatattg gttgacccat gtttatccac aatgatttct ccgcggtcgg
    56161 ttaggttgac accactatct ttgagccaag ctgtgtttgg aacaagacca atttgaacaa
    56221 agaccccttc aaggtcaagg tgtttgtctt caccgctatc acgctcagtg tagttaagac
    56281 ctgtaacatg gtcctctcca acaatgtcct tagtagcaac atttttgatg atggtcatat
    56341 tgttagtctt agctgcgcgg tcttgaagca ctttgtcagc tttaagttca ggcaagaatt
    56401 ctaaaacgta aacgtgttta gcaagaccag ccaagtcaag ggccgcttct aatccagagt
    56461 tcccaccacc gataacagca acatctttgc cttcaaagag aggaccgtca cagtgagggc
    56521 agtaagtcac ccctttatta cggaattcat cttcaccagg aacattaatg ttacgccatt
    56581 tggccccaag agctaagata gcagttttgg cttgtagaac cgcaccatta gctagagtaa
    56641 cctcgatgtt ttcttttttc tcaatagaag tagctagttg tgctttgata atatcaacat
    56701 cataagactt agtatgggcc tccacttcgg ccattaattt tggtccttca gtgtaaaggg
    56761 taccaatcat gttttcgatg ccgaccgttt ccatgacctg accaccaaag gtttcagcaa
    56821 gtaaacctgt ttttagtcct ttacgagctg catagatagc agcgctattg cccgcagggc
    56881 caccaccaat aacaaggaca tcatagaggc ctttatcagc aaaggcttcc tcagaaagtg
    56941 ggccagcgat ttgttctaag agttgctcaa tggtagcgcg accagaagtg aattcttccc
    57001 cgtctaaaaa gacagtaggg acagacataa tgccttttgc tttcacttca tcttggaaca
    57061 tgccgccttc taccatagtg tgtgaaatct tgtcgttcaa gacggacata atgtttaaag
    57121 cttgaacaac atctgggcag ttatggcagg ttaagctgac ataagtttca aaatgcaacg
    57181 gacggtcaat ggccttgatg cgatcaataa catcttgatc cacttttgga gcacgtccag
    57241 atacttgcaa gagagcaaga ataaaggacg tcaattcgtg gcctaaagga agaccagcaa
    57301 agacaacccc actaccgtga ccttttttcg caaccttaaa gcttggttgt cggtctaaag
    57361 tgatgttttc aatagaaata cgctcagaca tagcagctat ttcttccaca aagtctttga
    57421 ctttttgaga ctgctcattg tcaccaaggg aaacttgcaa aacaagatca gcttctaaca
    57481 gggtgaggta ttgggcaagt tgttctttaa tatcaggact taatgccata gctttcctcc
    57541 taaaatttat taaattttac caactaaatc aagacttggt gtcaaagttt cagcgccttc
    57601 tttccattta gctggacaaa cttcacctgg atgtttacgg acgtattggg cagcgtgaat
    57661 tttatcaatc aaggtgctag cgtcacgtcc aataccatca gcattaattt ccatcatttg
    57721 gataatacca tctggatcaa cgataaatgt tccacgttga gcaagtccgt cttcgccaag
    57781 cacttcaaag gcttgtgaaa taaggtgtga agggtcacca atcatagggt atgtgatagt
    57841 gccaaccaca tctgaatcat catgccaagc tttatgaaca aaatgagtat cagtagagac
    57901 agaataaact tctacaccaa gagatttcag tgtttcgtat tgctcttgaa ggtcaccgag
    57961 ttcagttggg caaacaaatg aaaagtctgc tgggtagaaa caaaaaactg cccattttcc
    58021 tttaacgtct tcatttgtaa cagtgatgaa ttttccatcg tgataagctt gagctgaaaa
    58081 ttcagcaatt tcttttccaa ttagagacat atagttgtcc tcctttttta tagttttata
    58141 cttgtattat aaaagaacaa caagattatg tctactcaga aacccttgat tttactggga
    58201 aatcagcgat tattttctga caattaagtt g
//
LOCUS       DAUGJR010000006        54732 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUGJR010000006 DAUGJR010000000
VERSION     DAUGJR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54732
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.006"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            185..1420
                     /gene="arcA"
                     /locus_tag="VH800_000355"
     CDS             185..1420
                     /gene="arcA"
                     /locus_tag="VH800_000355"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEQ8361452.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1520..1948
                     /locus_tag="VH800_000356"
     CDS             1520..1948
                     /locus_tag="VH800_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8361453.1"
                     /translation="MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            1988..3001
                     /gene="argF"
                     /locus_tag="VH800_000357"
     CDS             1988..3001
                     /gene="argF"
                     /locus_tag="VH800_000357"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEQ8361454.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3171..4664
                     /locus_tag="VH800_000358"
     CDS             3171..4664
                     /locus_tag="VH800_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEQ8361455.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4681..6012
                     /locus_tag="VH800_000359"
     CDS             4681..6012
                     /locus_tag="VH800_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEQ8361456.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPEGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            6032..6982
                     /gene="arcC"
                     /locus_tag="VH800_000360"
     CDS             6032..6982
                     /gene="arcC"
                     /locus_tag="VH800_000360"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEQ8361457.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7295..8287
                     /locus_tag="VH800_000361"
     CDS             7295..8287
                     /locus_tag="VH800_000361"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEQ8361458.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLGF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKQHIGEVQTSVWPQEVRDSYDNIL"
     gene            8410..8949
                     /gene="rsmD"
                     /locus_tag="VH800_000362"
     CDS             8410..8949
                     /gene="rsmD"
                     /locus_tag="VH800_000362"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEQ8361459.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8939..9430
                     /gene="coaD"
                     /locus_tag="VH800_000363"
     CDS             8939..9430
                     /gene="coaD"
                     /locus_tag="VH800_000363"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEQ8361460.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9417..10454
                     /locus_tag="VH800_000364"
     CDS             9417..10454
                     /locus_tag="VH800_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEQ8361461.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10811..10891
                     /locus_tag="VH800_000365"
                     /pseudo
     CDS             10811..10891
                     /locus_tag="VH800_000365"
                     /inference="COORDINATES: protein motif:HMM:NF019884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10868..11844
                     /locus_tag="VH800_000366"
                     /pseudo
     CDS             10868..11844
                     /locus_tag="VH800_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            12268..12912
                     /locus_tag="VH800_000367"
     CDS             12268..12912
                     /locus_tag="VH800_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEQ8361462.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRASKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12916..13995
                     /gene="rlmN"
                     /locus_tag="VH800_000368"
     CDS             12916..13995
                     /gene="rlmN"
                     /locus_tag="VH800_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEQ8361463.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(14077..14703)
                     /locus_tag="VH800_000369"
     CDS             complement(14077..14703)
                     /locus_tag="VH800_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEQ8361464.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEIGLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            14931..15458
                     /locus_tag="VH800_000370"
     CDS             14931..15458
                     /locus_tag="VH800_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEQ8361465.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            15600..15803
                     /locus_tag="VH800_000371"
     CDS             15600..15803
                     /locus_tag="VH800_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEQ8361466.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            15808..16779
                     /locus_tag="VH800_000372"
     CDS             15808..16779
                     /locus_tag="VH800_000372"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEQ8361467.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            16789..17178
                     /locus_tag="VH800_000373"
     CDS             16789..17178
                     /locus_tag="VH800_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEQ8361468.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRTKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            17361..19202
                     /gene="typA"
                     /locus_tag="VH800_000374"
     CDS             17361..19202
                     /gene="typA"
                     /locus_tag="VH800_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEQ8361469.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSVTKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            19324..19575
                     /locus_tag="VH800_000375"
     CDS             19324..19575
                     /locus_tag="VH800_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEQ8361470.1"
                     /translation="MFYLIMAVSIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            19945..21303
                     /locus_tag="VH800_000376"
     CDS             19945..21303
                     /locus_tag="VH800_000376"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEQ8361471.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            21303..22385
                     /locus_tag="VH800_000377"
     CDS             21303..22385
                     /locus_tag="VH800_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEQ8361472.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            22386..23534
                     /locus_tag="VH800_000378"
     CDS             22386..23534
                     /locus_tag="VH800_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEQ8361473.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMHDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQTPPSPETVLEQAHG"
     gene            23746..25110
                     /gene="ftsA"
                     /locus_tag="VH800_000379"
     CDS             23746..25110
                     /gene="ftsA"
                     /locus_tag="VH800_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEQ8361474.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            25134..26453
                     /gene="ftsZ"
                     /locus_tag="VH800_000380"
     CDS             25134..26453
                     /gene="ftsZ"
                     /locus_tag="VH800_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEQ8361475.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            26456..27127
                     /locus_tag="VH800_000381"
     CDS             26456..27127
                     /locus_tag="VH800_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEQ8361476.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIGEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            27139..27795
                     /locus_tag="VH800_000382"
     CDS             27139..27795
                     /locus_tag="VH800_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEQ8361477.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSSIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            27800..28054
                     /locus_tag="VH800_000383"
     CDS             27800..28054
                     /locus_tag="VH800_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEQ8361478.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            28054..28845
                     /locus_tag="VH800_000384"
     CDS             28054..28845
                     /locus_tag="VH800_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEQ8361479.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRVA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            28855..29613
                     /locus_tag="VH800_000385"
     CDS             28855..29613
                     /locus_tag="VH800_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEQ8361480.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            29886..32687
                     /locus_tag="VH800_000386"
     CDS             29886..32687
                     /locus_tag="VH800_000386"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEQ8361481.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNTKENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGTVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEYESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGVAFIVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(32952..33254)
                     /locus_tag="VH800_000387"
     CDS             complement(32952..33254)
                     /locus_tag="VH800_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEQ8361482.1"
                     /translation="MRLINTTSSHPELIKNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(33305..33760)
                     /locus_tag="VH800_000388"
     CDS             complement(33305..33760)
                     /locus_tag="VH800_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8361483.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(33888..36170)
                     /locus_tag="VH800_000389"
     CDS             complement(33888..36170)
                     /locus_tag="VH800_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8361484.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYIGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            36468..36698
                     /locus_tag="VH800_000390"
     CDS             36468..36698
                     /locus_tag="VH800_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEQ8361485.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            36825..37511
                     /locus_tag="VH800_000391"
     CDS             36825..37511
                     /locus_tag="VH800_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8361486.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            37511..38245
                     /locus_tag="VH800_000392"
     CDS             37511..38245
                     /locus_tag="VH800_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361487.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVMFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            38394..39803
                     /locus_tag="VH800_000393"
     CDS             38394..39803
                     /locus_tag="VH800_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEQ8361488.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKNLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            39981..41675
                     /locus_tag="VH800_000394"
     CDS             39981..41675
                     /locus_tag="VH800_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8361489.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            41883..42737
                     /locus_tag="VH800_000395"
     CDS             41883..42737
                     /locus_tag="VH800_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEQ8361490.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            42890..44230
                     /locus_tag="VH800_000396"
     CDS             42890..44230
                     /locus_tag="VH800_000396"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEQ8361491.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            44208..44423
                     /locus_tag="VH800_000397"
     CDS             44208..44423
                     /locus_tag="VH800_000397"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEQ8361492.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            44423..45295
                     /locus_tag="VH800_000398"
     CDS             44423..45295
                     /locus_tag="VH800_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEQ8361493.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            45288..46115
                     /locus_tag="VH800_000399"
     CDS             45288..46115
                     /locus_tag="VH800_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HEQ8361494.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            46102..46572
                     /locus_tag="VH800_000400"
     CDS             46102..46572
                     /locus_tag="VH800_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8361495.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            46594..48255
                     /gene="recN"
                     /locus_tag="VH800_000401"
     CDS             46594..48255
                     /gene="recN"
                     /locus_tag="VH800_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEQ8361496.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDILNSLTRKYGGNVNDVLDYYDNIVKEY
                     QLLTGDDLSSGDLEAELKSLEKQLVAAASELSVSRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            48427..49368
                     /locus_tag="VH800_000402"
     CDS             48427..49368
                     /locus_tag="VH800_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8361497.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLNEL
                     DELDEENEEDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLR
                     SLSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAH
                     YEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYSRKLGMAVAK
                     RKIALPQTGEGFSYYPVLLGLMILGLTPIMIPKKINN"
     gene            49584..50435
                     /locus_tag="VH800_000403"
     CDS             49584..50435
                     /locus_tag="VH800_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8361498.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            50428..51270
                     /locus_tag="VH800_000404"
     CDS             50428..51270
                     /locus_tag="VH800_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEQ8361499.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            51248..51835
                     /locus_tag="VH800_000405"
     CDS             51248..51835
                     /locus_tag="VH800_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEQ8361500.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTEKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            51934..52209
                     /locus_tag="VH800_000406"
     CDS             51934..52209
                     /locus_tag="VH800_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEQ8361501.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(52299..53441)
                     /locus_tag="VH800_000407"
                     /pseudo
     CDS             complement(52299..53441)
                     /locus_tag="VH800_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051793.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(53565..53831)
                     /locus_tag="VH800_000408"
     CDS             complement(53565..53831)
                     /locus_tag="VH800_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEQ8361502.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            complement(53843..54223)
                     /locus_tag="VH800_000409"
     CDS             complement(53843..54223)
                     /locus_tag="VH800_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEQ8361503.1"
                     /translation="MTIEEILDFHNVELAYFDNELWPRPGIYIDEIKVVFVNRALSDE
                     SKKKVIFHELGHIEHDSGQYQRRHEEFELQANRHMIRCLLEDEFDKVEDKHEFNYLSF
                     MQRHNLKTTTDEVMVIDEYYTLIG"
     gene            complement(54227..54574)
                     /locus_tag="VH800_000410"
     CDS             complement(54227..54574)
                     /locus_tag="VH800_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361504.1"
                     /translation="MFITFERIKELAKKQGLSINSLEEKMGYSRNTIYALKRNKPGSE
                     KLQEIADYFHVSTDYLLGRTDNPAIAKDNQEYTSEDLRKMAKNAKTFDGKPLTESDIE
                     AIQNIIEIYLKGR"
BASE COUNT        17278 a         9473 c        11397 g        16584 t
ORIGIN      
        1 acaagtaaac gaatacaaat ctataaaaat aaaaacaacg ctcaaaaaat gtaagcgatt
       61 actcaaaata gctgtgagaa ataccctatt tttatctttt ttaaggagta cactaggaat
      121 ataagcaaga gttaagaatc ttgacggtga attcacaaaa accaattaga aagaggtaat
      181 tcttatgact gctcaaacac caattcatgt ttattctgaa attggaaaat taaaaaaagt
      241 gttgctccac agacccggta aagaaattga aaatcttatg ccagactact tggaacgctt
      301 gttgtttgat gatattccat tcttagagga tgcccaaaaa gaacatgatg cttttgccca
      361 agctttgcgt gacgaaggta ttgaagtctt gtaccttgag accttagctg cagaatctct
      421 tgtcactcca gaaattcgcg aagctttcat cgatgaatac ctaagtgaag ctaatatccg
      481 tggaagagct actaaaaaag ccattcgtga attgttgatg gctatcgaag acaatcaaga
      541 attgattgaa aaaaccatgg caggagttca aaaatctgaa cttccagaga tcccagcatc
      601 tgaaaaaggc ttgactgact tggttgaatc caattaccca tttgccatcg acccaatgcc
      661 aaacctttat ttcacacggg acccattcgc aactatcggt acaggtgttt ctcttaacca
      721 catgttctca gaaacccgta accgtgaaac cctttatggt aaatacattt tcactcatca
      781 cccaatttat ggtggtggca aagtgcctat ggtttatgac cgtaatgaaa ccactcgcat
      841 tgaaggtggg gacgaacttg ttctttcaaa agatgtgctt gcggttggta tttctcaacg
      901 tacagatgct gcttctattg aaaaattgtt ggttaacatc tttaaacaaa accttggctt
      961 caagaaagta ttggcctttg aatttgcaaa taaccgtaaa tttatgcact tagacactgt
     1021 ctttaccatg gttgactatg acaaattcac cattcaccca gaaattgaag gcgaccttcg
     1081 tgtttactct gtcacttacg acaatgaaga acttcatatc gttgaagaaa aaggtgattt
     1141 agcagaactt cttgctgcta accttggtgt tgaaaaagtt gaccttatcc gttgtggtgg
     1201 tgacaactta gtagcagcag gtcgtgaaca atggaacgat ggttctaata ccttgaccat
     1261 cgcaccaggt gtggttgtgg tttataaccg taacaccatt accaatgcca ttcttgaatc
     1321 taaaggcttg aagttgatca agattcacgg aagtgaattg gttcgcggtc gtggtggacc
     1381 tcgttgtatg tcaatgccat ttgaacgtga agatatttaa taagctatgg taaaggtggt
     1441 tataggtcag aagccttttt aaagggcagc tagtgtttat cttcgcttct gtgtctttgt
     1501 ccttcaatga aattttgtca tggcagataa atttgatgcc aatgacgaaa caagaacggt
     1561 ttatgcagtc gtttatgaca atgaccagcc cgtttcaaca ggacaatttt tagctgaaac
     1621 gaaaatagaa gcacgattga cacgcattgt aaccttagca gattattgtg gttgcggtta
     1681 tggtgccaaa gtcactgaag cgctcgaaac ttataccaga cgagaaggct tttaccaact
     1741 aaccattcac agtgaactga cagcacaaac cttttatgaa aacctaggtt atcagtccta
     1801 tggtcccaag tgtttagaag atggtgagta ttgtcagtcc cttgcaaaaa ccattcttaa
     1861 atgggagaag aatatggaca tagcaatgct aattgcgatt gttggtggtc tattaggctg
     1921 ctatctctat ctcacaaaaa ataattaatc aaaacagatt acagttaaca ctcgaaggag
     1981 acaatagatg acacaagtat ttcaaggacg tagcttccta gcagaaaaag attttacacg
     2041 cgctgaatta gaatacctta ttgatttttc agcacatttg aaagatttga aaaaacgtgg
     2101 tgtgcctcat cactacttag aaggtaaaaa cattgccctc ttgtttgaaa aaacatcaac
     2161 tcgtacgcgt gcagctttta caacagcagc cattgaccta ggtgctcacc cagaatacct
     2221 cggtgccaat gacatccaac ttggtaaaaa agaatcaaca gaagacactg ctaaagtatt
     2281 gggtcgtatg tttgatggga ttgaattccg tggctttagc caacgcatgg ttgaagaatt
     2341 ggcagaattc tcaggtgtgc cagtttggaa tggtttgact gatgaatggc acccaaccca
     2401 aatgcttgct gactatttaa cagtgaaaga aaactttggc aaacttgaag gccttaccct
     2461 tgtttactgt ggtgacgggc gtaataacgt tgccaattcc cttcttgtga ctggtgctat
     2521 ccttggtgtt aatgttcata tcttctcacc aaaagaactt ttcccagaag aagagattgt
     2581 gacattggct gaaggctatg ctaaagaaag tggcgctcgt atccttatca cagaagatgc
     2641 tgacgaagct gttaaaggcg cagacgtgct ttacacagat gtttgggtat caatgggtga
     2701 agaagacaaa ttcaaagaac gtgttgaatt gcttcaacca tatcaagtca acatggacct
     2761 tgttcaaaaa gcaggaaatg acaagcttat cttcttgcac tgcttgccag ctttccatga
     2821 cacaaatacc gtttatggta aagacgttgc tgaaaaattc ggcgtgaaag aaatggaagt
     2881 cactgatgaa gtcttccgca gcaaatacgc tcgtcatttt gaccaagctg aaaaccgcat
     2941 gcacactatc aaagcggtta tggcagcaac ccttggtaac ctctttattc caaaagtgta
     3001 ataaggactg gtactcctta actcatttca catatcaatg tgaccccttt aatttaacaa
     3061 tttaactact taaaaacgta ctttaactac atgacaagtc gttctggttt tcgcgtcctt
     3121 gaccggaact agaacggctt atttttatga aaaggtaaga ggtaatcatt atgacagaag
     3181 aaaaaaaacg gggttttaga attccttctt cttacaccgt tctttttatc attatagcca
     3241 tcatggcagt gttaacttgg tttattccag ctggcgccta cgaaaccgct aagggcggtg
     3301 gtgttatttc aggaacctac aaaacagtag catccaatcc tcaaggattt tttgacatct
     3361 tgatggctcc cgttcgaggc atgttaggtg ttgaaggcac tgatggtgct attcaagtgt
     3421 ctttctttat cttaatggtt gggggctttt taggagttgt caacaaaaca ggtgctcttg
     3481 acacagggat tgcgtcagtg gttcgtaaaa acaaaggtag agaaaaaatg ctgattgcta
     3541 ttttaatccc tttgtttgct ctaggtggaa cgacctatgg tatgggggaa gaaaccatgg
     3601 ccttttaccc acttttaatt cctgttatga ttgcggttgg ttttgacagt attgttgctg
     3661 tagccattat tttgattggt tctcaaattg ggtgtctagc ctccactatt aacccatttg
     3721 caactggtgt agcagctgat gctgctggtg tcagcattgc agatggaatg atttggcgtg
     3781 ttatccaatg ggttattctt gtcggcatgt ctatttggtt tgtttacaat tacgctagta
     3841 agattgaaga agacccaagt aaatcattgg ttgcagacaa ggaagaagag cataaggaac
     3901 tcttccagtt gcaaaattct ggagaagact taaacaagcg ccaacgaaac gttttgacca
     3961 tttttacttt gacctttgtc attatgattc ttagtttgat tccgtgggaa gattttggca
     4021 tcaaattctt tactaatatc aatacttggt taaccacaat gcctatctta gggggagtta
     4081 ttgggaaaac catgggagca tttggtactt ggtatttccc agaaatcacc atgctcttta
     4141 tcatgatggg tgtcttagtt gctattgttt atcgtatgag tgaagaagac ttttttagct
     4201 cttttttgac tggtgcaggt gaatttttag gtgttgccat gatctgtgct attgcacgcg
     4261 gtattcaagt tatcatgaat ggtggtatga ttacagccac tatcttacac ttaggtgaaa
     4321 caagtctttc tggtttatct tctcaagttt ttgtgatatt agcttatatt ttctacctcc
     4381 caatgtcctt cttgattcca tcaacatcag gacttgctgg ggctacaatg ggaattatgg
     4441 caccgcttgg acaattctca aatgtccctg ctcaccttgt tattacagcc ttccagtcag
     4501 cttctggaat cttaaacatg atttctccaa cttcagcaat cgttatggga gcacttgcgc
     4561 ttggtcgcgt tgaccttggt acttggtgga aattcattgg taaatttatt gtaatggtga
     4621 tgcttgtaag cgtgctatta cttgtagttg caacattctt ttaacagata ggaggttcct
     4681 atggaatcct atatcacacc taaacatcaa gaggcctgtg tagctgccat taaacagatc
     4741 gtttcttacc cttctgtttg tcatgaagga gaaaatggca caccttttgg acaggccatt
     4801 caagatgttc tcgaagcaac cttagactta tgtcaaggtc ttggttttca tacttatatt
     4861 gatcctgaag gttactatgg ctatgctgag ttaggtgacc aaaaagaggt cttggctatt
     4921 ctttgccatt tggacgttgt tccagaagga gatcgtcagt tatggaagac agatcctttt
     4981 gactgtgttg aggcagacgg ctgtttattt ggtcgaggca ctcaagacga taaaggtcct
     5041 actatgatgg cgctatttgc caccaaagcc ttgatagatg caggcgttac ctttaataaa
     5101 cgcattcgtt ttattttcgg aacagatgaa gaaactttgt ggcggtgtat gaatcgctac
     5161 aatgatgtag aagaacaggc tacctttggg tttgctcctg attcaagttt ccctttaacc
     5221 tatgccgaaa aaggcctact tcaggcaaaa ttagtgggga aaggttctga taaactgtca
     5281 cttgaaatcg gacaagccta caatgttgtt cctgcaagag cctcttatca aggtgataag
     5341 cttgaggctt tacaaaaaga actagataag cttggctttg agtacgtcgt caaagaggga
     5401 gaattaacgg tttatggtct cgcccaacat gctaaagatg ctcccgatgg catcaacgct
     5461 atgattaggc ttgccaaggc tttagtggtc cttgaaccta acaaaaccct tgattttctt
     5521 gctaatgtca ttgatgaaga tggcagagca cttaatattt ttggcagaat cgaagatgaa
     5581 ccttcaggca aattaagctt taatgccgca gggcttacct taaccaaaga caaggcagaa
     5641 attcgcctag atattcggat tccagttttg gcagataagg aaaaattagt ccaacaatta
     5701 agccaaaaag cacaagaata cggcctaacc tatgaagaat ttgattattt ggccccatta
     5761 tatgtgccat tagacagtga attggtaaca accttgttat ctgtctatcg gaaaaaaaca
     5821 ggtgatcaaa gccctgccca atcatcagga ggggcaacct ttgctagaac aatgaagaat
     5881 tgtgttgcct ttggtgccct tttccctgat gctgttcaaa cggaacacca agaaaatgaa
     5941 catattgttt tagcggatgc ttaccgcgct atggatattt atgcggaagc tatttaccga
     6001 ctaacgcgat aacaagatat gaggagtaat tatgacgaaa caaaaaatcg tagtcgcact
     6061 tggaggaaat gctattcttt caacagatgc gtcagcaaaa gcacaacaag aagccttgat
     6121 ttccacatca aaatcactgg ttaaattaat taaagaaggt catgaagtca tcgtgaccca
     6181 cggcaatggc ccacaagttg gtaatctctt gttacaacaa gcagcagcag attctgaaaa
     6241 gaatccggct atgcctttgg atacttgtgt tgccatgaca gaaggtagca tcggtttttg
     6301 gttagttaat gccctcgata atgaattgca agcccaaggt attcaaaaag aagtggcagc
     6361 tgttgtcact caagtgatcg tggatgccaa agacccagct tttgaaaacc caacaaaacc
     6421 aattggtcca tttcttaccg aagaagatgc caaaaaacaa atggcggagt ctggtgcaag
     6481 tttcaaagaa gatgcaggtc gtggctggcg taaggttgtg ccatcaccaa aaccagttgg
     6541 tattaaagaa gccaatgtca tcagaagtct cgttgattct ggcgttgttg tggttagtgc
     6601 tggtggtggc ggtgtgcccg ttgtggaaga tgctactagc aagaccctga ctggtgtgga
     6661 agctgttatt gacaaggact ttgctagtca aaccctttca gaattggtgg acgcagacct
     6721 ctttatcgtt ttgacaggag ttgataatgt ttacgtcaac ttcaacaaac ctgaccaagc
     6781 caaattggaa gaagtgactg tctctcaaat gaaagaatac atcacacaag accaatttgc
     6841 accaggtagt atgttaccaa aagtggaagc tgccattgct tttgttgaaa acaaaccaaa
     6901 tgctaaagcc attatcacat cgctcgaaaa tattgacaat gtactatcag caaacgctgg
     6961 aacacaaatt atcgcagggt aatcaagagg atttttagtt ctgtttaaaa gactcattta
     7021 atggtatttt ctgaagagta cgactgacat aaagagttga tactgttttt aaaggaaaag
     7081 agtgtgccat aataaaaaac aataatagta ttagaaaagg ctaattttat tgagaattag
     7141 ccttttcttt tagctttgat aggtgtataa taaccatact attttttatt tttcaaaata
     7201 ttagaataaa caaaagtgga caacgtataa agagaactgc taagtcgttg agctcattag
     7261 tcccaaaaag attaccaaaa aagaaggaag aactatgaag aaaagtttta ttcatcaaca
     7321 agaggagatt tcctttgtta agaatacgtt cactcagtat ttgattgcta agttagatgt
     7381 tgttgaagtg caaggaccca ttttaagtcg ggtcggggac ggtatgcaag ataatttgtc
     7441 cggtactgaa aatccagtat ctgtcaatgt cttgaaaatt cctaatgcaa cctttgaagt
     7501 tgtgcattca ttagcaaaat ggaaacgtca caccttagcc cgttttgggt ttaatgaagg
     7561 tgaaggcctt gttgttaata tgaaggctct ccgacctgat gaggattcac ttgaccaaac
     7621 ccattctgtc tatgttgacc aatgggactg ggaaaaagtc atccctgatg gcaaacgtaa
     7681 tctcgcttac ctcaaagaaa ccgttgaaac catttacaag gtcattcggt taactgaatt
     7741 agctgtagaa gctcgttatg atattgaggc tgttttacct aagaaaataa ccttcattca
     7801 taccgaagaa ttggtagcta aataccctga tttgacgccc aaagaacgtg aaaatgccat
     7861 tactaaagaa tttggagcag tctttttaat tggtattggc ggggttttac ctgacggtaa
     7921 accacacgat ggccgcgctc ctgactatga tgactggaca acagaaactg aaaatggcta
     7981 tcatgggctt aatggtgata ttttggtttg gaatgaccaa cttggttcag cctttgaatt
     8041 atcctcaatg gggatccgtg tggatgaaga ggccctaaaa cgtcaggtgg aaatgactgg
     8101 tgaccaagac cgcttaggct ttgattggca caaatctttg ttgaatggac ttttccctct
     8161 aacgattggt ggaggaatcg gtcaatcacg tatggtcatg tttttgttgc gtaaacaaca
     8221 tattggagaa gttcagacct ccgtttggcc ccaagaagtt cgtgatagct acgataatat
     8281 tttataagta atcacatcat tttgctaagt tttccacttg tataagagac tttaaataaa
     8341 tgatcagaaa tattgaaaaa agaaatcatt tttaaggttt agagctagaa atttgctata
     8401 ataaatgtta tgagagttgt atcaggtgaa tttggtgggc gtcctttaaa gacgctcgat
     8461 ggaaagataa cacgccctac ttcagacaaa gttagaggtg cgatttttaa tatgatagga
     8521 ccttacttta atggtggtcg tgttttagat ttgtttgcag gttcaggtgg attagccatt
     8581 gaggctgttt ctcgtgggat gtctgctgca gttttggttg agaagaatcg taaagcgcaa
     8641 gctattattc aagacaatat tataatgact aaagctgaga atcggtttac cttgttaaaa
     8701 atggaagctg agcgagctat tgattgcttg actggtcgat ttgacttagt ctttttagac
     8761 cctccttatg ccaaagaaac aattgtggca actattgaag ctttagcagc taaaaactta
     8821 ttgagtgaac aggttatggt tgtctgtgag acagataaaa cagtcttgtt gccaaaagag
     8881 attgcaacgt taggtatttg gaaagaaaaa atttatggaa ttagtaaggt aacagtttat
     8941 gttaactaaa ataggacttt atacagggtc atttgatcct gttacaaacg gtcatctcga
     9001 tattgttaaa cgggcaagtg gcctatttga tcaaatatat gttgggattt ttgataatcc
     9061 taccaaaaaa agctatttta aactagaagt tcgtaaagca atgcttactc aagctctggc
     9121 tgattttaca aatgtaattg tagtaacttc gcacgaacgt ttagctattg atgtagctaa
     9181 agaattacga gtaactcact tgattagagg cttgcgaaat gcaactgact ttgagtatga
     9241 agaaaatttg gaatatttta atcacctttt agctccaaat attgaaaccg tctatttgat
     9301 atcaagaaat aaatggcagg cccttagctc tagtcgtgtg agagagctaa ttcattttca
     9361 gtcttcctta gaaggtttgg ttcctcagtc ggttattgct caagtggaga aaatgaatga
     9421 aaagacttaa aaaaatcaaa tggtggttag tgggtctgct agctttaatc tctttgttgc
     9481 tagcgttatt ttttccgcta ccttattata ttgaaatgcc tggaggcgct tacgatattc
     9541 ggactgtctt acaagtcaat ggcaaagaag acaaacgaaa aggagcttac cagtttgttg
     9601 cagtgggcat tagtcgtgcc agcctcgctc agctattata tgcttggctg acaccgttta
     9661 ctgaaattag tacagcagaa gatacaacag gcggatacag cgatgctgat ttccttcgaa
     9721 ttaatcaatt ttacatggaa acatcacaaa atgcagctat ttatcaagct ttatccttag
     9781 ctggaaaacc agttacatta gattataaag gcgtatatgt tttagacgta aacaacgaat
     9841 ctacttttaa aggaacgcta cacttagcag atactgtaac aggtgtaaat ggtaaacagt
     9901 ttactagttc agcagaactt attgactatg tttctcacct aaaactaggg gatgaagtta
     9961 cggttcagtt tacgagtgat aataagccta aaaaaggagt tggccgtatt atcaaactga
    10021 aaaatgggaa aaatgggatt ggcattgcct tgactgatca tacaagtgtc aattcagaag
    10081 acacagtgat ctttagtact aaaggagtag gaggacctag tgctggtcta atgtttactc
    10141 ttgatatata tgatcaaata actaaagaag atttacgcaa gggccgtaca attgcaggta
    10201 caggaactat tggcaaggat ggcgaagtag gagatattgg tggtgcaggt cttaaagtag
    10261 ttgcagcagc tgaagctggt gcagatatat tttttgttcc gaataatcct gttgataagg
    10321 aaattaaaaa agttaatcca aatgctataa gtaattacga agaagccaaa cgggcagcca
    10381 aacgactaaa gaccaaaatg aagattgttc ctgttacgac tgttcaagag gcactggttt
    10441 atcttcgcaa ataaaataac tatgaatgta ttatattcaa ttatattcac gctattaact
    10501 cataaaaaac ggttgaacca gatagacaga tccttgacca gtcttttggg ttcaatcatt
    10561 ttttacataa aacatatcta acttgacagc gtaaaaaaga tgttataaaa gtctagtggt
    10621 aaaaaggcaa tagagaattg agtaaacttt agtcgattat ctggaaatag agcatactaa
    10681 aaacacctag tgaaaattga tttttttcac tagctcatcc aagaacttgc gcagataatc
    10741 atgagtccat tccatgactc tattattctg gaaagccttg caatagacaa gttaacgtta
    10801 taacaactaa attaaaaact tgagattgaa aaatccccat aaacttattt tacaaggagg
    10861 taaggctatg gtaaccatta aacaagttgc tgaagaagca ggtgtttcta gatcaacagt
    10921 ctccaggtat atttctcaaa aaggatatgt atctgatgat gcaaggcata aaatcaaagc
    10981 agcgatagca aaattacatt acactccaaa tgtcttggcg cagtcattga agacgaaaaa
    11041 aatcaactag tcggtttatt attaccagac atttccaatc ctttttttcc gaggttagca
    11101 agaggagcag aagaatattt aaaagaaaag gggtatcggg ttatgctagg aaatatttca
    11161 gacagcgaag ctcttgaaga agaatacgtc catgtccttc ttcaaagcaa tgctgctggc
    11221 attattacta cccatgactt tacaaagcgg tatcctactc ttgctattcc agttgtagtg
    11281 gtagatcgtg ttgaccaaga gacccagtac ggtgtctttt cagataatag ggcagggggc
    11341 ttattggcgg ctcagactgt ctggcaagca ggggcaaaag aagttttgtt aataagaggt
    11401 ccgctggata atgctgaaaa cattaatgag cggtttgaag ctagtttttc ttaccttcaa
    11461 aaacaagacg tgactatgta tgtgtgtgat agtcagaatt ttgattttga aagtattcag
    11521 ctagaagcta gttacaacct caagtgttac ccaacaatag acagtattat agcaccttct
    11581 gatatccatg ctattgctta tattcatgaa ctgcattctc aaggtaaaaa gattcctcaa
    11641 gatgttcaaa taataggtta tgatgacatt ttaatgagtc aatttattta tccttcttta
    11701 tcgactattc atcaatcctc ttatttgatg ggccgttatg ccgccgaatt agtttatact
    11761 attgctagtc aattaactgt gaaagcaaat cggattaaat tgcctgttca ctacgttgag
    11821 cgagaaacaa taaggaaaag ataagtaata atattagtcc agattttagc aggtatgatg
    11881 aagatttatt gggatttacc ttctacttta aaagaagtta tctgtcatta ctttcatcgc
    11941 tatcagtcaa aatgcattct tatgcaactc ttaaccttaa gcttaatgtc tttttgataa
    12001 catagaggaa tgttacacga tgatgatgca ataaagccta aatatagtaa ttgtcgtgat
    12061 tttatagcta gtgagtaatg agatagcaag tctctcattt acttacaaaa gtcaaaaaat
    12121 agtgtataat ggttgagtta cagataacac tgcaaaaaag ataacaagtg tccataatta
    12181 tctaagacta taaaggcgat atagacagat ataaaaaaga tgacgaatca gttatcactg
    12241 gacaattaac cgatttagtt acaactaatg gatttttcag aaaggtgtca aatgaaaaaa
    12301 gaaatttcgc cagaaatgta caactataat aaatttccag gtcccaaatt tattcatttt
    12361 gaagagcaag ttaaggctga aggcattgat ttgttactct tagaagatgt taagaacgct
    12421 tttgatacga ctagctttgg tcaacgttat acagaagttc tcctaaagta tgactatatt
    12481 gttggcgatt ggggaaatga acagcttcgt cttaaagggt tttataagga tagtgacgat
    12541 atcaagaaaa cgaatcgcat ctcacgttta gaagattata ttaaagaatt ttgcaatttt
    12601 ggttgtgctt attttgtttt agaaaatctt catccacaag atattaaatt tgaagaggag
    12661 cgccaaccaa gacgaaagaa atcacctaaa tcaaaatcaa atcgtcgcaa gccaaactat
    12721 tcaaatcagc agcccgcaac acctaagagc aaatcgaagc gggcatcaaa agaaaagcaa
    12781 cctgaaaacc aagcgtttac cagtcaaaaa cgtcgaagta atactaagca taaagaaaag
    12841 tcaaaacgta atcagactag tcaacttaat accaaaatta gtcattttat catcagaaag
    12901 aaagataaat aatccatgaa accatcgatt tatagcttaa cacgcgatga actgatcgcg
    12961 tgggcagttg aacgcggcca aaaacagttt agagctactc aaatttggga ttggctctat
    13021 aaaaaaagag ttcaatcttt tgaggagatg acgaatattt ctaaagattt tgtttctatt
    13081 ttaaatgata gtttctgtgt caatccttta aaacagcgag ttgtacaaga gtcagctgat
    13141 ggtacagtaa aatatttatt tgaactgccc gatggtatgt taattgaaac agttttaatg
    13201 cgtcaacatt atggtcattc tgtttgtgtg acgactcaag ttggctgtaa cattggctgt
    13261 actttttgtg ctagtggatt gatcaaaaag caacgtgatc taaacagtgg ggaaattaca
    13321 gctcaaatca tgttagtcca aaaatatttt gacgatagaa agcaaggtga gcgggttagc
    13381 catgttgtcg taatgggcat tggtgaacct tttgataatt acaaaaatgt catgtgcttt
    13441 cttcgcgtca tcaacgatga taatggctta gcaattggtg cccgtcatat tacagtctct
    13501 acctcagggt tagctcacaa gattcgggat tttgcaaacg agggagtaca ggttaactta
    13561 gcagtctcgt tgcatgcacc aaataatgat ttacgttcaa gtattatgcg agtaaatcgc
    13621 tcttttccgc ttgaaaagct cttttcagct atagaatact atattgaaaa aacgaatcgt
    13681 cgtgtcactt ttgaatacat tatgctaaat gaagttaacg atagcattaa gcaagctcaa
    13741 gaattagcag acttaactaa aactattcgt aagttatctt atgttaactt gattccgtat
    13801 aatcctgttt cagaacatga tcagtatagt agaagtccta aagagcgagt tctagcgttt
    13861 tatgatgtgc taaagaaaaa tggagttaac tgtgtggtgc gtcaagagca cggaacagat
    13921 attgatgcag cctgtggcca gttacgttct aaaacgatga aaaaagatcg cgaaaaggtt
    13981 acagcgacaa aataaagccc aaaaaatatc tttgattgac aatgcttgat gacaaaatat
    14041 tcctagtcac taaaatgact aggtttttta tctggcctaa aaatgctcta gaagcacaat
    14101 ccaaaataat ccaaaactaa gataaggaat aaaaggtatg cgcttgatgc ctaatagtaa
    14161 gcaagcagta atacctgcta aactagcaag ttgaattagc caaatcaacg acgttagatc
    14221 caatactaaa gctaagctag caaggtagaa aaaatcgcct gctccaattg aaaaaggtct
    14281 taaatgagct aataaaccta gtagcagtaa tatcaatgat aaataattga tcgaataaaa
    14341 caggagtaga cttacaaagc taaaaagcca caagataaaa gggtattctt gagaacgcca
    14401 atcaaataaa ctaaataata aagaaaagag taacaagtaa cagtaactag cactaaccca
    14461 atgtaccata ctagcccata agataattat tagacctatc tctaagctaa agaagatttt
    14521 ttggctagtt ataaaatggt tttggaactg ccgaaaaacg cgtttggcaa aagttagttg
    14581 gtcacaaaca atgacagtct gtttacttag ctgctcttga ccattatcag gaaaataaag
    14641 tagtaaacag taaaaaagat gggtcaataa gatgcccgaa catatactaa aaaaagctat
    14701 catacttatt tattcgaaaa gaaatcaaat acttgcaatc tttccttaat cattgtagaa
    14761 tatagatata aaacgataat gattctaatt aagtgtctaa tcatccaatt aggattattc
    14821 cgttattgtc gaataggatt aggtccttaa ccctttctta tgtttatcac gttagggtta
    14881 gttccctctc cattcttgcc ctttaagctg aaaagtaagg agatgttatt atgacaaaca
    14941 cactcgttga aaatatttat gcttcagtaa ctcacaatat ttctaaaaaa gaagcatcaa
    15001 aaaatgaaaa aactaaagct gttttaaacc aagctgtcgc tgacttatct gtggctgcat
    15061 ctattgtgca ccaagtacac tggtatatgc gtggtccagg tttcttgtac cttcacccca
    15121 aaatggatga attacttgat agcttgaatg ctaatttaga tgaaatgagc gagcgtttga
    15181 tcactattgg cggagcgcct tattctaccc tagctgagtt ttctaaacac tctaaattgg
    15241 acgaagcaaa aggtacttac gataaaaccg ttgctcagca tttagcaaga ttggtcgaag
    15301 tttaccttta cctcagcagc ctttaccaag ttggtttgga tattaccgat gaagaaggcg
    15361 atgctggaac aaacgatttg tttacagcag ctaagacaga ggctgaaaaa accatttgga
    15421 tgctccaagc agagcgtgga caaggcccag cactctaatt gattatgcct taggataaaa
    15481 gaagtcaatg ataaaattgg cttctttttt atggaatcat cgattcattt tcagaaacat
    15541 agaaagcgat tccatacttg tcttgaaatc tgccgtagaa tttgctaaaa tctacttata
    15601 tgaaaacact atatgatgtg caacaattgc taaaaaactt tggcattttt gtttaccttg
    15661 gcaaacgtct ttatgatatt gaaatgatga agattgaact tcagcgtctc tatgatagcg
    15721 gcttattgga taagagggat tacttaaatg cggagttaat tttgcgacgt gagcatagat
    15781 tagaattgga aaaagaagga tagacaaatg agtcaaaaat tactggggat tgatttaggt
    15841 ggtaccacca ttaaatttgg aattttaaca gcagcaggag aagtccaaga aaaatgggca
    15901 attgagacta atattttaga aggaggcaaa catattgtcc ctgatatcat cgcttccatc
    15961 aaacatcgct tagacttgta tggtctaagc agtgctgact ttgtgggaat tggtatggga
    16021 tcaccaggag cggttgaccg tgatactaat acagttactg gggcattcaa ccttaattgg
    16081 aaagaaaccc aagaagtcgg ttccgttgtt gaaaaagaat tgggcattcc ttttgccatt
    16141 gacaatgatg ccaatgtggc tgcccttggt gaacgttggg taggtgctgg tgaaaataac
    16201 ccagatgtcg tcttcatgac acttggaaca ggtgtcggtg gaggcattat tgctgatggt
    16261 aacttgattc atggtgttgc aggagcaggt ggtgaaatcg gccacatgat tgttgagcca
    16321 gaaaatggct ttgcttgtac ttgtggctca cacggctgtt tggaaacagt agcttcagca
    16381 acaggagttg tcaaagtggc acgtttactg gcagaagcct acgaagggga ttcagccatc
    16441 aaagcagcta ttgacaatgg tgaaggtgtt accagtaaag acattttcat ggcggctgaa
    16501 gcaggggatt cctttgctga ttctgttgtg gaaaaggttg gttactacct tggccttgct
    16561 tcagcaaata tttccaatat cttgaatcca gactcagtgg ttatcggtgg gggtgtgtca
    16621 gcagcaggag aatttctacg ctcacgtatt gaaaaatact ttgtgacctt cactttccca
    16681 caagtgaggt attcaactaa aattaagatt gcagaacttg gcaatgatgc tggaattatc
    16741 ggtgcagcta gccttgctcg acaatttatc acaaaatagg agggggatat gtctccaatc
    16801 acacttatct tatggttact tcttgtcggc attgttggtt attatacatg gaactatttc
    16861 tcttttcgaa aaatggcaaa gcaggttgat aacgagactt ttaaagacgt gatgcgtcaa
    16921 ggtcaattga ttgatttacg agagccagcg gcttttagaa ctaagcatat tttaggagct
    16981 cgaaattttc cagcgcaaca atttgatgct gctattaagg gactacgcaa ggacaaacct
    17041 gttcttattt acgaaaatat gcgtccccag taccgtgtgc ctgcggtcaa aaaacttaaa
    17101 aaagctggct ttgaagacgt ttatgtctta aaagacggta ttgattattg ggatggcaaa
    17161 gttaaacaaa caacctagtt aagagtaacg tggagttaag gggaataaag gcagtcactg
    17221 tctcaaaaac cttaattcct ttttttgctg tatccagact tgctgaaagt ctgaaaacat
    17281 ttacaattga ttaaaaccag ttttttaaaa cattttgtgt tatacttatc tagttaaaat
    17341 atatttactt agaggaacaa atgactaact taagaaacga tatccgtaac gtagcgatta
    17401 ttgcccacgt tgaccacgga aaaacaacac ttgtagatga attattaaaa caatcccata
    17461 ctcttgatga gcgtaaagag cttcaagagc gtgccatgga ttccaatgac cttgaaaaag
    17521 aacgtgggat tacaatcctt gcgaaaaata cggcagtagc ctataacgat gttcgtatta
    17581 acatcatgga taccccagga cacgcggact tcggtggtga agttgaacgt atcatgaaaa
    17641 tggttgacgg ggttgttctt gttgtggatg cctacgaagg aacaatgccc cagacgcgtt
    17701 tcgtattgaa aaaagcactt gagcaaaacc ttatcccgat cgttgtggtg aacaagattg
    17761 acaaaccttc agctcgtcca gcagaagttg tagatgaagt gcttgaatta ttcatcgaac
    17821 ttggtgccga tgatgagcaa ttggaattcc cagttgttta cgcatcagct attaatggaa
    17881 catcatcatt atcagatgac cctgctgacc aagagcatac tatggcaccg atctttgata
    17941 cgattattga tcatattcca gcgccagttg ataattcaga tgagcctttg caattccaag
    18001 tgtcactttt ggactacaac gatttcgtag gtcgtatcgg tatcggtcgt gttttccgtg
    18061 gtactgttaa agtgggtgac caagtaactc tttcaaaact tgatggtacc actaaaaact
    18121 tccgtgttac aaaactgttt ggtttcttcg gtttggaacg tcgtgaaatt caagaagcta
    18181 aagcaggtga cttgattgct gtttcaggta tggaagatat ctttgttgga gaaaccatta
    18241 caccaactga ctgtgtggaa gctctgccaa ttcttcgtat tgatgagcca acacttcaga
    18301 tgactttctt ggtcaataac tctccttttg caggtcgtga aggtaaatgg atcacgtcac
    18361 gtaaggttga agaacgtctt ttagcagaat tgcaaacaga cgtgtcactt cgtgttgacc
    18421 caacagattc gccagataaa tggacggttt cagggcgtgg agaattgcat ttatctatcc
    18481 tcattgaaac catgcgccgt gaaggctatg aacttcaagt atcacgtcca gaagttatca
    18541 tcaaagaaat tgatggtgtc aaatgtgaac cgtttgagcg tgttcaaatt gatacaccag
    18601 aagaatatca gggtgcaatc atccagtctc tttcagaacg taaaggggat atgcttgata
    18661 tgcagatggt tggtaatggt caaacgcgtt tgattttctt gattcctgca cgtggtttga
    18721 ttggttattc aacagagttt ctttcaatga cacgtggata tggtatcatg aatcatactt
    18781 ttgatcagta tctaccggtt gttcaaggag aaatcggtgg ccgtcatcgt ggtgccttgg
    18841 tttctattga aaatgggaaa gcaacgacat attcaatcat gcgtattgaa gaacgtggaa
    18901 ctatctttgt caatccaggt acagaagttt acgaagggat gattgttggt gaaaactcac
    18961 gtgataacga ccttggtgtt aacattacaa cagctaagca aatgacaaat gtccgttcag
    19021 tgactaaaga tcaaactgca gttatcaaga cgcctcgtat cctaacgctt gaagaatcat
    19081 tagagttctt gaatgacgac gaatacatgg aagtaacgcc agaatctatc cgcttgcgta
    19141 aacaaatctt gaataaagct gcgcgtgata aagctaataa aaagaaaaaa tcagccgaat
    19201 agcttttgaa gttaaactaa ctaaataaaa tagcaaaaag atatttaaga aaagtcattt
    19261 tttaaaggtc tttttgcgtt tacaagttcc tatggaatat aaaccaaaat aaaggaggac
    19321 ggaatgtttt accttattat ggctgtctcg attatatctt attatctata catggctcct
    19381 aaaagtgtcc gtaacaccct tgggatgatt ggtttagttg gcttggttgc tctgcttatt
    19441 gttttagcgg gcttgagttt tatcaaaatc atgcaaaccc ctcctgaatt ttttattggg
    19501 atgggaatgg tggcattggg ctattttgct ttaaaagatg tgcgtaaaat gaccaaaaaa
    19561 ccgagagtta aataaaaata cttaaataaa aatacttaaa gattgatgat tttggttttt
    19621 atacgataaa aggactgatt tgttttagac aatatcagtc cttttttaat agttcatttt
    19681 ttctgaaaga aagcttttag ccgattttca ttgagtgtgc aactaaaaag agatgcttgg
    19741 tagtgacagt taagacctct gactagtatt ttatcttatt ttacttaaaa aaacgtatca
    19801 ataatctcac aaatatgggc atgatgtttg tatattggaa acggattcta attctaaact
    19861 caagaacggt atttttaaaa tgttgaaaaa gcatctaaat aaaggtaaaa tagaaatcaa
    19921 atagaatgga tagtgtgagc ttagatgaaa gtgataagta attttcaaaa caaaaaaata
    19981 ttaatattgg ggttagccaa atcgggcgaa gcagcagcaa aattattgac caaacttggt
    20041 gctttagtga ctgttaatga tagtaaacca tttgaccaaa atccagcggc acaagccttg
    20101 ttggaagagg ggattaaggt catttgtggt agccacccag tagaattatt agatgagaac
    20161 tttgagtaca tggttaaaaa ccctgggatt ccttatgata atcctatggt taaacgcgcc
    20221 cttgcaaagg aaattcccat cttgactgaa gtagaattgg cttatttcgt atctgaagcg
    20281 cctattatcg ggattacagg atcaaacggg aagacaacca caacgacaat gattgccgat
    20341 gttttgaatg ctggcgggca atctgcactc ttatctggaa acattggtta tcctgcttca
    20401 aaagttgttc aaaaagcaat tgctggtgat actttggtga tggaattgtc ctcttttcaa
    20461 ttagtgggag tgaatgcttt tcgccctcat attgctgtca tcactaattt aatgccgact
    20521 cacctggact atcatggcag ttttgaggat tatgttgctg ctaaatggat gattcaagct
    20581 cagatgacag aatcagacta ccttatttta aatgctaatc aagagatttc agcaactcta
    20641 gctaagacca ccaaagcaac agtgattcct ttttcaactc aaaaagtggt tgatggagct
    20701 tatctgaagg atggaatact ctattttaaa gaacaggcga ttatagctgc aactgactta
    20761 ggtgtcccag gtagccacaa cattgaaaat gccctagcaa ctattgcagt tgccaagtta
    20821 tctggtattg ctgatgatat tattgcccag tgcctttcac attttggagg cgttaaacat
    20881 cgtttgcaac gggttggtca aatcaaagat attaccttct acaatgacag taagtcaacc
    20941 aatattttag ccactcaaaa agctttatca ggttttgata acagtcgctt gattttgatt
    21001 gctggcggtc tagatcgtgg caatgaattt gacgatttgg tgccagacct tttaggactt
    21061 aagcagatga ttattttggg agaatccgca gagcgtatga agcgagctgc taacaaagca
    21121 gaggtctctt atcttgaagc tagaaatgtg gcagaagcaa cagagcttgc ttttaagctg
    21181 gcccaaacag gcgatactat cttgcttagc ccagccaatg ctagctggga tatgtatcct
    21241 aattttgagg ttcgtgggga tgaatttttg gcaacctttg attgtttaag aggagatgcc
    21301 taatgcctaa gaagatttta tttacaggtg gtggaactgt aggtcatgtc accttgaacc
    21361 tcattctcat accaaaattt atcaaggacg gttgggaagt acattatatt ggtgataaaa
    21421 atggcattga acatacagaa attgaaaagt caggccttga cgtgaccttt catgctatcg
    21481 cgacaggcaa gcttagacgc tatttttcat ggcaaaatct agctgatgtt tttaaggttg
    21541 cacttggcct cctacagtct ctctttattg ttgccaagct tcgccctcaa gccctttttt
    21601 ccaaaggtgg ttttgtctca gtaccgccag ttgtggctgc taaattgctt ggtaaaccag
    21661 tctttattca tgaatcagat cggtcaatgg gactagcaaa caagattgcc tacaaatttg
    21721 caactaccat gtataccact tttgagcagg aagaccagtt gtctaaagtt aaacaccttg
    21781 gagcggtgac aaaggttttc aaagatgcca accaaatgcc tgaatcaact cagttagagg
    21841 cggtgaaaga gtattttagt agagacctaa aaaccctctt gtttattggt ggttcggcag
    21901 gggcgcatgt gtttaatcag tttattagtg atcatccaga attgaagcaa cgttataata
    21961 tcatcaatat tacaggagac cctcacctta atgaattgag ttctcatctg tatcgagtag
    22021 attatgttac cgatctctac caacctttga tggcgatggc tgaccttgta gtgacaagag
    22081 ggggctctaa tacacttttt gagctactgg caatggctaa gctacacctc atcgttcctc
    22141 ttggtaaaga agctagccgt ggcgatcagt tagaaaatgc cacttatttt gagaagaggg
    22201 gctacgctaa acaattacag gaacctgatt taactttgca taattttgat caggcaatgg
    22261 ctgatttgtt tgaacatcag gctgattatg aggctactat gttggcaact aaggagattc
    22321 agtcaccgga cttcttttat gaccttttga gagctgatat tagctccgcg attaaggaga
    22381 agtaaatggc aaaagataaa gagaaacaaa gtgatgacaa gctcgttttg acagagtggc
    22441 aaaagcgtaa cattgaattt ttaaagaaaa agaagcagca agctgaggaa gaaaaaaaac
    22501 tcaaagagaa attattgagt gataaaaaag cgcagcagca agctcaaaat gcttctgaag
    22561 cggttgagct taaaactgat gagaaaactg atagtcagga aattgagtca gaaacgacgt
    22621 caaaacctaa aaaaaccaaa aaagttagac aacccaagga aaaaagcgcg acacaaatcg
    22681 cttttcaaaa atccttgcct gttcttttgg gggcgctctt actcatggcg gtgtctattt
    22741 ttatgatcac tccttatagc aaaaagaaag agttttctgt aagaggaaac catcaaacga
    22801 accttgacga attaatcaaa gctagcaaag tcaaagcatc tgactattgg ttaacgctgt
    22861 taacttcgcc tggtcagtat gaacgaccga ttcttcgtac tattccatgg gtgaaatctg
    22921 tacatctctc ttaccaattt cctaatcact ttctatttaa cgttattgaa tttgaaatca
    22981 tcgcttatgc acaagttgaa aacggttttc agcctatttt ggagaatgga aaacgtgtgg
    23041 acaaggtcag ggcatcagaa ctaccgaaat ctttcttgat tcttaattta aaagatgaga
    23101 aagcgatcca acagttagtt aagcaattaa cgacattacc taaaaaatta gtcaagaata
    23161 tcaagtcagt gtctcttgca aattccaaaa cgacagcgga tttactactt attgaaatgc
    23221 atgacggtaa tgtagttaga gtaccgcagt cacaactcac attgaaactt ccctattatc
    23281 aaaaattgaa aaaaaacctt gaaaatgata gtatagtgga tatggaagtg ggaatttata
    23341 ctacaacaca ggagattgaa aatcaacctg aagttcctct tacgcctgaa caaaacgcag
    23401 ctgataaaga aggagataag cctggtgaac atcaggaaca gacagacaat gattcagaaa
    23461 cgccagcaaa tcagagtagt cctcagcaaa caccaccatc cccagaaacg gtcctcgaac
    23521 aggcccatgg ctagctaata tctaagttga aaaagcaatg aaaacgttag aaattcaacg
    23581 attctaaccc ataatgaatt gcctaaaaaa aattaagttt atataacaaa aaacgtaaaa
    23641 tgataacatt ttacgttttt ttatggtata atattttctg aatgattctg ttttttagca
    23701 gtttttagaa tagcaaaagt ttggaaagta agtgaggtca agtgaatggc tagaaatggc
    23761 ttttttactg gtttggacat tggaacaagc tcgataaaag ttttagtagc agaatttatt
    23821 tctggtgaga tgaacgtcat tggtgttagt aatgttccaa gtaccggcgt aaaagatggc
    23881 ataataatcg atatagaggc agctgcgact gccatcaaaa ctgcggtaga acaagcagaa
    23941 gaaaaagcag ggatgacaat tgaaaaggtt aatgttgggc taccggcaaa ccttcttcaa
    24001 attgaaccaa cacaaggaat gattcctgtc ccaagtgagt ctaaagagat aaaagatgag
    24061 gatgttgata gcgttgttaa atcggcttta acaaaaagta tcacaccaga acgagaggtt
    24121 atctctttag ttccagaaga gttcattgtg gatggctttc agggcattcg agatccacgt
    24181 ggtatgatgg ggattagatt agagatgcgc gggcttattt atactggacc aagcaccatt
    24241 ttacataatc tgcgtaaaac ggtagaaaga gcaggcatta aagttgaaaa catcattatt
    24301 tctccgttag ctatggctaa aaccatttta aacgaaggtg agcgcgagtt tggagctact
    24361 gtaattgata tgggaggtgg acagacaact gtcgcttcta tgcgagcaca agaattgcag
    24421 tataccaata tatatgccga aggcggcgaa tacattacta aagatatatc aaaagtatta
    24481 aaaacgtctt tggctattgc agaagcactt aagtttaatt ttggtcaagc ggagatatca
    24541 gaagctagta taactgaaac agtaaaagtt gatgtggtag gtagtgaaga gcctgttgag
    24601 gtaactgaac gttatttatc tgaaattatt tcagcgcgta ttcgtcatat tttagatcgt
    24661 gtgaagcaag atttggaaag aggtcgttta ctagacttac caggaggcat tgttttgatt
    24721 ggtggcggtg caatcatgcc tggagtggta gaaattgcac aagaaatctt tggagtaact
    24781 gtaaagctcc atgttccaaa ccaagtcggt attagaaatc caatgttttc aaacgttatc
    24841 agtttggtag aatatgttgg tatgatgtct gaagtagacg ttttagcaca aactgcagtt
    24901 tcaggagaag aacttttgcg acgcaagcct atcgatttca gtggccaaga atcttattta
    24961 ccagattatg atgattcaag aagaccagaa tcgaccattg gctatgaaca acaagcgtca
    25021 caaacagcat atgattcaca agttccgagt gatcctaaac aaaaaatttc agaacgtgtt
    25081 cgtggcatat ttgggagtat gtttgattaa aagtaataaa gtgaggaaat aaaatggcat
    25141 tttcatttga tactgcatca attcaaggtg caattataaa agtaattgga gtcggcggag
    25201 gtggcggaaa tgccattaat cgtatgattg atgaaggtgt tgctggtgtc gagttcatcg
    25261 cagcaaacac agacattcag gcattaagct catcaaaagc tgaaacggtt attcaactag
    25321 gccctaaatt aactcgtgga cttggtgctg gaggacaacc tgaagtagga cgtaaagctg
    25381 ctgaagaaag cgaagaaatt ttaacagaag ctcttacagg agcggacatg gtatttatta
    25441 ctgccggtat gggtggtggc tctgggacag gggctgcacc ggttattgct cgtatcgcta
    25501 aaagtttggg agccttgaca gtagctgttg ttactcgccc gtttggtttt gaaggtaaca
    25561 aacgtggtaa ttttgctatt gaaggtatcg aagaactacg tgaacaagtt gatactttgt
    25621 taattatttc aaataataac cttcttgaga ttgttgataa aaagacacct ttattagaag
    25681 cacttagtga agctgataat gttttacgcc agggagttca agggataacc gacttaatta
    25741 ctagtcctgg ccttatcaat ctcgattttg ccgacgtgaa aacagttatg gcaaataaag
    25801 ggaatgcctt gatggggatt gggattggct ctggagaaga gcgcattgtt gaggcggcgc
    25861 gtaaggcaat ctattcaccc ctattagaaa cgactattga tggtgcacaa gacgttattg
    25921 tgaacgttac aggaggtctc gacatgacac ttacagaagc tgaagaagcc tctgaaattg
    25981 ttgggcaagc tgctggtcaa ggcgttaaca tttggttagg aacatctatt gatgatacta
    26041 tgaaagatga catccgtgtg actgttgtag caactggagt gcgccaagaa aaagccgaac
    26101 aagtttcagg ttttcgtcag cctaggactt ttacccaaac caacgcgcag caagtagcgg
    26161 gtgcacaata tgcatcagat caagcaaaac agtcggttca accagggttt gatcgtcgct
    26221 caaattttga ttttgacatg ggggagtctc gcgagatacc aagtgcacaa aaggtaattt
    26281 ctaatcataa tcaaaatcaa ggttctgctt ttggaaattg ggatttgaga cgtgataata
    26341 tttctcgtcc aacagaaggt gaattggata accatcttaa tatgtcaacg ttctcagcta
    26401 acgatgacag tgatgatgaa ttagaaacgc ctccattctt taaaaaccgt taataatgga
    26461 tttactgaca aataaaaaga aaatttttga gactatccgc ttatctacag aggcagcaaa
    26521 taggactaat gatagtgttt cagttattgc tgtaacaaaa tatgtggata gtacaattgc
    26581 aggtcagctt atcgaagcag gaattgagca cattgccgaa aaccgtgttg ataaatttct
    26641 tgaaaagtat gatgcgttaa agtatatgcc agtaaagtgg catttaattg gtaccttaca
    26701 acgtcgtaaa gtcaaggaag ttatcaatta tgttgattat tttcacgctc tagattctgt
    26761 gagattagct ttggaaatca acaagagagc tgaccatcct gtgaagtgtt ttctacaagt
    26821 taatatttct aaagaagaga gtaaacatgg ttttaacatt tctgagattg atgaagcgat
    26881 tggagaaata ggtaagatgg agaagataca gttagttggt ttaatgacta tggcaccagc
    26941 aaatgccagt aaagaaagta ttataactat ttttcgacaa gcaaatcaat taagaaaaaa
    27001 cttgcagtta aaaaaaagaa agaatatgcc ttttacagaa ttgagcatgg gcatgagtaa
    27061 cgattatcca attgctattc aagaaggctc aacttttatt cggattggta gagctttctt
    27121 tcactaatgg agaataagat ggcttttaaa gatacattta acaagatgat ttcttatttt
    27181 gacacggatg aggttaacga agttgaagaa gatgttgcag catcaactga taacgttatt
    27241 ccaagatcac aacaatcagt cagagcaagt agtcatccaa aacaagaacc tagaaacaat
    27301 cacgtacaac aagatcatca agcgagatcc caagaacaga caaggtcaca aatgcatcca
    27361 aaacatggca cttctgaacg ctattatcag cagtctcagc caaaagaagg ccatgaaatg
    27421 gttgacagaa gaaaacggat gagcacttct agtattgcaa atcgccgtga gcagtatcaa
    27481 caatcaactt gttcagatca aacaactatt gccttaaagt atcctcgtaa atatgaggat
    27541 gctcaagaaa ttgtggatct tttaatagtt aatgaatgcg ttttgattga ttttcagttt
    27601 atgctagatg ctcaggctag acggtgttta gattttattg atggtgctag taaagtgctc
    27661 tatggtagct tacaaaaggt cggctcttca atgtacttac tggctccgtc aaatgtatcc
    27721 gtcaatatag aagaaatgac tatcccacat actacacaag atattggctt tgattttgat
    27781 atgaaaaggc ggtaaataaa tgatattaat actatctatt cttcttcgtc tgatcaaagt
    27841 ttacacttat ttattgattg cttacgcatt aatgtcatgg tttcctgggg catatgattc
    27901 aaaaattggg cgtttgatta gtggtatcgt tgaaccaatt ttaaaacctt ttagagcatt
    27961 taatttacaa tttgccggtc ttgacttcac tatttttgtc gtcattatta gtttgaattt
    28021 tttagctcaa gttttggtcc gtgtgtttat ttaatggtta gtcatagtaa gatttatcag
    28081 cattttcacc aagaagaata tccttttatt gatagaatgt ctgatatgat taatagagtt
    28141 gaagattact atcttttaga agttactgag tttttaaatc ctagagaagt gatgatttta
    28201 aaaagtttga ttgctttaac agatctaaaa atgttcgtat caacagatta ctacccaagc
    28261 gaatatggtc gtgtcattat tgcacctggt tactatgact tagaacaaag tgattttcaa
    28321 atagctttag tagagataag ttatcaggca aagtttaatc agttgacaca tagtcaaatt
    28381 ttaggaactt taattaatga attaggagta aagcgaaatt tatttggaga tgtttttgtt
    28441 gaaatgggat atgcccagct catgattaag cgggagttat tggattattt tttaggaaca
    28501 attactaaaa tagctaaaac tagtgtgaaa ttaagagaag ttaactttga tcagttaatt
    28561 aggtctattg ataacagcca gaccctggat attctagttt ctagttttcg attagatggt
    28621 gtagttgcta ctatcttaaa aaaatctcga acgcaagtta tagcattaat tgaagcaaat
    28681 aagattaagg taaactatcg agttgctaat aaagcttcag ataatctagt cataggggat
    28741 atggtgagta tcagaggtca cgggcgtttt actcttttag cagataatgg agtgaccaaa
    28801 catggcaaac aaaaaataac actaagtaaa atgatacata aataaggaga tacaatggca
    28861 cttacaacgc tagaaattaa agataaaact tttaagacaa aattccgagg atactgtgaa
    28921 gaagaagtca atgaattcct tgatattgtt gttgatgatt acgaagctct tgtacgtaaa
    28981 aatcgtgata acgaagcaag aattaaagat cttgaagaaa aattatctta ctttgatgaa
    29041 atgaaagagt cacttagcca gtctgtaatc ttagctcaag aaacagctga aaaagtgaaa
    29101 gcaacggcta atgcggaagc aacaaacttg gttagtaaag cgacttatga tgctcagcat
    29161 ttattagatg aatctaaagc taaagccaat caaatgttgc gtgatgcaac tgatgaggct
    29221 aagcgagttg cgattgaaac agaagaacta aagcgtcaaa cacgtgtgtt ccaccaacgt
    29281 ttaatctcat ctattgagtc acaattaagc ttatcaaatt cacctgaatg ggatgaactg
    29341 ctacaaccga ctgcaatcta tcttcaaaat tctgacgatg cttttaagga agtcgtgaag
    29401 accgttctta atgaagacat tcctgaatct gatgatagtg cctcttttga tgcaacacgt
    29461 cagtttactc cagaagagtt agaagaattg caacgtcgtg ttgatgaaag caataaggag
    29521 ttagaggctt accaacttga ctctcaatct gattctacga ctgagccaga ggtaaatctc
    29581 agtgaaacac aaacgtttaa attaaatatc taaataaaga aaaacaagat gatttgctta
    29641 taatcacagc aagcgggaga tgatgagagt ctcgtattcc ctaagtatta tcattatcat
    29701 tttctaaaat tttcgctgaa ctacagtaag cgaggaggtt tgttcacctt acgagcaaag
    29761 agggagcggt aagtcttatg atatattatc gctctgaact aaggtggtac cacgagcttt
    29821 cgtccttttt gagacgaggc ttttttcgtt atagtcgcaa gtttgtttaa aaggagtttg
    29881 aaataatgaa attaaaagag acacttaatc taggaaaaac agcctttcca atgcgcgcag
    29941 gtcttcctaa taaagagcca caatggcaag cagcttggga acaagcagag ctttacaaaa
    30001 aacgtcaaga attgaatgca ggtaagcctg cctttcatct tcatgatgga cctccatacg
    30061 ctaacggcaa tattcacgtt gggcatgccc ttaataaaat ttcaaaagat atcattgtgc
    30121 gttctaagtc catgtctggc tttcaagcgc cttatgtacc tggttgggac acacacggcc
    30181 ttccaatcga acaagtcttg gctaagcaag gaatcaaacg taaggagatg gatttagcag
    30241 aataccttga gatgtgtcgt caatacgctt taagtcaggt tgataaacag cgagatgatt
    30301 tcaaacggtt aggtgtttcg gcagactggg aaaatcctta tgtcactttg gacccacagt
    30361 ttgaagctga tcaaattcgt gtttttggag cgatggctga aaaaggttac atctatcgtg
    30421 gtgctaaacc tgtttattgg tcatggtctt cagaatcggc cttggcagag gctgaaattg
    30481 aataccatga catcgattca acctctttat actacgccaa taaagttaaa gatggtaaag
    30541 gtatccttga tactaatacg tatatcgttg tttggaccac aacaccattt accgttacag
    30601 catcacgcgg tttgactgtt ggtcctgata tggattatct tgtggtgaaa cctgctggtt
    30661 cagaccgtca atatgttgtg gcagaaggtc ttttggatag ccttgctgga aaatttggct
    30721 gggaatcttt tgaaacttta gctagccata aaggagctga tttagagtac attgtgacag
    30781 aacacccatg ggatactgac gtagaagaat tggttatcct tggtgaccat gttacccttg
    30841 agtcagggac agggattgtc cacacagcac caggttttgg tgaggatgac tacaatgttg
    30901 ggacaaaata caaactggaa gttgctgtga ctgttgatga acgtggccta atgatggaaa
    30961 atgcaggtcc agatttccac ggacaatttt ataacaaggt aacgccgatt gtcattgata
    31021 aacttggtga tcttttattg gcacaagaag tgatcaatca ctcttaccca tttgactggc
    31081 ggacgaaaaa accaatcatc tggcgtgctg taccgcaatg gtttgcttct gtttctgatt
    31141 tccgtcaaga tattttggat gaaattgaaa aaacaacctt tcatccatca tggggtgaaa
    31201 cacgccttta caatatgatt cgtgatcgtg gcgactgggt tatttctcgt caacgtgctt
    31261 ggggagttcc gcttcctatc ttctatgccg aagatggcac agctattatg actaaagaag
    31321 tgacagatca tgtggctgat ttgttccaag aaaatggatc aatcatttgg tggcaaaaag
    31381 aagctaaaga cctattacca gagggcttca ctcatccagg gtcaccaaat ggcgagttta
    31441 caaaagaaac tgatatcatg gacgtttggt ttgactctgg ttcttcttgg aatggagtca
    31501 tgaatactaa agaaaatctt tcctatccag cggatctata cttagaaggc tctgaccagt
    31561 atcgtggttg gttcaattca tccttaatta catctgtggc tgttaatggg catgctccat
    31621 ataaggctat tttatcgcaa ggctttgttc ttgatggtaa gggcgaaaaa atgtctaaat
    31681 caaaaggcaa tatcatttct cctaatgatg tggctaaaca atatggtgca gatattcttc
    31741 gactttgggt agcttctgtg gataccgata atgatgtccg tgtttctatg gagatccttg
    31801 gtcaagtctc tgaaacttac cgtaaaatcc gtaacaccct tcgcttcttg attgctaata
    31861 catctgattt caaccctgct acggatacag tagcttatgc agatttagga actgttgata
    31921 agtacatgac aattgtcttt aatcagttgg tagcaacgat tactgacgct tatgagcgtt
    31981 atgactttat ggctatttac aaagcagtgg tgaactttgt tacggttgat ttatcagcct
    32041 tctatcttga ttttgctaaa gacgttgtct atattgaagc tgccaatagc ttagaacgtc
    32101 gtcgcatgca gacagtcttc tatgatatct tggttaagat taccaagtta ttgacgccaa
    32161 tcttgcctca cactactgaa gaaatctggt cttatctaga gtatgagtca gaagcatttg
    32221 ttcaattggc agaaatgcct gtggcagaaa ccttctcggc tcaagaggat attttagaag
    32281 cttggtcagc tttcatgact ttgcgtactc aagctcaaaa agctttggaa gaagcgcgaa
    32341 atgctaagat tatcggtaaa tcattggaag cccatttgac catctacgct agtgaagaag
    32401 tgaaaacctt attgactgct ttagacagcg atattgcttt gcttttgatc gtgtctcaat
    32461 taaccattgc tgacttggca gatgcgcctg cggatgcagt ggcatttgaa ggtgttgcct
    32521 ttatagtaga acatgccata ggtgaagttt gtgagcgttc acgtcgcatc gacccaacta
    32581 ctcgcatgcg ttcttacaat gcatttgtct gtgatcacag cgctaaaatc attgaagaaa
    32641 atttcccaga agctgtggct gaagggtttg aagagagtgg caaataagtc ttatcaagac
    32701 ttgaagtgac actgagtaag aagacaacca tcgggtctta ggacctgatg gttttttagt
    32761 agagctgatt acgtccatta gccagcttta acgagagaca aagtaggaga aatttagact
    32821 acttttttaa tttcttttaa gaaaattgct ggcttcatat aaggactatt aagatagagt
    32881 tcacctttcg ctaataaaaa aacttagctc ttttagaagg gctaagtttt gtctgaatag
    32941 ctggctgctg tttatacaga agtttgaaat gaaatttcaa taaggttatt cgtgtgaagt
    33001 gtttttgatt gtccaggaat aacaatttta ggatcaattt tacgttttaa aaaaaattcg
    33061 cgaatgatat caagttcatc ctccttgatg gcacggtatt tatttgaaat aagtagttcg
    33121 taatgttttg gtgcttgggt aaaaatgaca tctgtatttc ctgctgagta tacttcgact
    33181 aaataggcat cggtgttttt tagctgattt ttgatgagtt ctgggtgact gctagtggta
    33241 ttgatgagtc tcataaatgt cctccttagt attcctgtac ctattatagc actaatttaa
    33301 agccttagtt agtagaatga tgcttttttt gccattcctt gactccccat tgatggctct
    33361 ctcgttttaa tttagcaatt gcctcgatag gagaaaacca acctaagtta ttaaaatctt
    33421 ctaagggctt agaaacggct tgaaatgcag ttacttcata aagataggca ggatggtaga
    33481 agtgggtatc acgatggcga gagtagaaat attcatctgc ctgaccgtaa tatgaaccaa
    33541 tagtagcaga aaaaccaagt tcttcaatca gttcacgctc tagggcctga agctgacctt
    33601 cacctgcttc aatttcacca ccaggtaaaa accaggaacc attaggagct tgaacaagaa
    33661 taatttttgt ttgttcgtga ttgggaatga tagcatagac accgtaacgt gtgacatagt
    33721 ctttatgtgc atttttatgt ccaaatgttg gaatcatcat tttatttacc tttccttttt
    33781 cttcattata ctaaattttt gctaattatt cttatcaatt tgtttagttt aataaaaaat
    33841 tgatagaaaa agagagagtc tccttataga aactctctta gctaacgtta atcgagagac
    33901 tcttcgttaa gaaaagaatc tccctcttta acagctttaa tcgtgatatt ttcactgttt
    33961 gtcatcagtg cacgtaactg tttttcagtt gggtgttcta aataatagtc tgtaatggca
    34021 tcttcgatat aatcttgaat agtacgacgg agcggccgag cgcccatttt aggatcatag
    34081 cctaaatcta ctaatttttc tttgaccttt tgtgtcacat caagatgaat cccattatag
    34141 cctaagcgct cattaacatc ttccagcatt aaatcaacga tatgcagcaa atgctcttta
    34201 gataaagctt tgaattcaat aataccatcg aaacgattca taaactctgg gctgaagaag
    34261 ttgcttaatt caccaaggac agaacttgtc cgtccttctc tagcagcacc aaatccgaca
    34321 gaagcttcgc ttttacctgt tccggcatta gaggtcatga taataatggt gtccttgaag
    34381 ctgactgttc gtccttgacc atctgttaaa cggccatcat caagaacttg taagaacatg
    34441 tgcatgacgt caggatgggc tttttccacc tcatctaaga gaataagtga atatggattg
    34501 cgacgaactt gttcggttag ctgtccagct tcttcatagc cgatataacc tggaggagcc
    34561 ccgactaatt tggcgacagc gtgtttttcc atgtattcgg acatgtcaaa gcgaatcata
    34621 ttgtttgtcg aaccaaagag ttcaatggct agttgtttag acaattcagt tttaccaacc
    34681 ccagtcggtc caacgaataa gaaagaacca atagggcgat ttggagttcc taatcccaca
    34741 cggttacgac gaatagcctt agcgatttta tcaacagcat cgtcttgccc gatcacgtgt
    34801 gctttcagat cattggctaa gtttacgagt tgagactgtt ccttttcttt taagtcccca
    34861 actggaatat tagttttttg ctctacaata gcttcaatgg ttttttcagt aatgatggga
    34921 atatcttgct catcgacttt ttgagcctgc atttctttgt attttgtaat ttgatcgcgg
    34981 aaataagctg cgcgttcata gtcttcgtct cgagtagctt gcgccttgag attctcagct
    35041 tcaataagac gtttgtcaat ttctttagga tcaacaaagt tgagggttag attcattttg
    35101 gaaccagctt cgtccagaag gtcaatagcc ttatcaggaa gaaaacggtc ttgaatatag
    35161 cggttagata aatgagcggc agcttcaata gcggctgggc tatatttgac atgatgatag
    35221 tcttcgtatt tcggttggat accttttaaa atcgtgatgg tttcctcaac agaaggttca
    35281 tcaactttaa cgggttgcat acgtcgttct aaggcagcgt ctttttcaat aatacggtat
    35341 tcatttaatg tagtagcacc aacgagttgc aactcaccac gggccaaggc tggttttaaa
    35401 atattaccag catccatatt gccgtctcct gcagaaccag caccgacaat ctcatgaatt
    35461 tcatcaataa agagaatcac atccttgcga ttgcgaattt cttccattaa tttttgcatg
    35521 cgctcttcaa actgaccacg gatacctgtt ccctgaacga ggctaaccac atcaagacga
    35581 atcacttgct tgccttggag tttttgagga acagtaccat caataatttt ttgagccaaa
    35641 ccttctacaa cagcagtttt accaactcca ggctcaccaa ttagcacagg attattttta
    35701 gtacggcggt tgaggatctc gataacgcgt gtaatctctt cgtcacgacc aataacagga
    35761 tcaatattac catttcttgc aatatctgtg acattaatcc caaactcttc taacaagccc
    35821 tttgcttgct gatttggtgt ttgtggctga gcaggtcgtt gtccgttgta gttaccacca
    35881 tagcgtcctc cgccatttcc attttgccct gcctgagtag gtggggtatt tggaagatta
    35941 ccaaaagctc taaaattatt caaatcacca aaaaagtcat caaagaaagg acttgtggat
    36001 ctatcttgtg ctctatatcc tggggttagg ccatttaaaa tagaattggc aggatcggat
    36061 ttcatgattt gataacaatt ttgacagaga tcaacctgtc tttgttttcc attaacactt
    36121 gtataaagat gaatagtaga ttcgtttaaa ttacaatttt gacacagcat aatatacctc
    36181 cgagggttta tctaaaagtc aaagtcattt agtcaaaaat ggtcaaactt tatattcata
    36241 ttatagcacc acggcttggg aaatcaagta aaaagtttat cgctttagcg ttagctttta
    36301 gagagtaaca tgacagagta actttattaa gtttccaatg agcaaatgtt taaaatcatt
    36361 gaaaagagta aaaaaagtaa aatatcaata aatatattac tttccttgtt agtttccctt
    36421 gttttgtgtt aaaataagag ggataaaaaa cgaataggag aaacgaaatg gaatcacatt
    36481 tggtgagaat catcaatcgt ttggagttga tggtgacaga tggcggtaat ctcaagcgaa
    36541 attttgaacg cgatggtgtt gttgttgcag aagttgcctt ttcaaatgat cctgaaaatg
    36601 gacctgtttt cacattgcgt gatgttgaag cgcgtgagtc atattccttt gatagcattg
    36661 acttgattgc aatggaaatc tacgatttat tatattaagc ttgacatagt aaagagactt
    36721 gcctgaggca ggttttttta ttgtcaaaaa gtattgtatt aatattcatc agatggtata
    36781 attatcttta ttgtaatgaa cctaggactt atgaggagat ataaatggat ttgtcatttt
    36841 tgcccaaata ctgggcctac tttaactacg gtgtacttgt caccattatg atttcagtca
    36901 gcgttgtctt ttttggaacc cttattggtg tcttggtaac cctgattaag cgtagtcatg
    36961 tgaagccgtt gacctgggtc gttaatcttt acgtttggat ctttcgggga acacctatgg
    37021 tggttcaaat catgattgcc tttgcttgga tgcattttaa caatatgcct actattggtt
    37081 ttggggtttt agacttggac ttttcaagac tacttcctgg aattattatc atttcattga
    37141 atagcggtgc ttatatttca gaaattgtta gagcaggtat tgaggctgta ccaaaagggc
    37201 aattagaagc agcttattca ctaggtattc gtcctcaaaa tgccatgcgt tatgtgattt
    37261 tgcctcaggc ctttaaaaat attttgccag ccttaggaaa tgaatttatt accattatta
    37321 aggatagtgc tcttttacaa accattggag tgatggaact ttggaatggt gcccaatcgg
    37381 tggtaacggc tacttattct ccaatttccc ctttactggt ggctgctttt tactacttaa
    37441 tggtcacaac agtgatggca cagttattgg cagtcttaga acgtcacatg gcgcaaggag
    37501 gtaatcattg atgactgagg ctattatttc aattaaagac ttgcacaagt attatgggca
    37561 caatgaagtg cttaagggaa ttgatttaga cattatgcca ggagaggttg tggtgattat
    37621 tggcccttct ggttctggaa aatcgacctt acttcgaacc atgaatcttt tggaagtacc
    37681 aactaaggga cagattaggt ttgaggggat tgatattacc gataagaaga atgatatttt
    37741 cagcatgcgt gaaaaaatgg gaatggtttt ccagcagttt aacctctttc ccaatatgac
    37801 tattttagaa aatatcactt tatcgccaat caaaactaag ggaatggcta aagcagaggc
    37861 tgacaaaaca gccttgagct tgttggacaa agttggatta tcagaaaaag ccaaggctta
    37921 tcctgctagt ctttctggtg ggcaacagca gcggattgcg attgcgcgtg gactggctat
    37981 ggatccagat gttttactct ttgatgaacc aacttcagct ctagacccag aaatggtggg
    38041 tgaggtcttg gctgtcatgc aagatttggc taaatctggg atgactatgg ttattgtgac
    38101 tcatgaaatg ggctttgcta aagaagtcgc agaccgtgtg atgtttatgg atggcggcgt
    38161 tattgtggaa gaaggaagtc ctaaccaact ttttgatctg actaaagaag aacgtacaaa
    38221 agattttttg agtagagtat tataaatctg ttctatgaat tataaaagga agtcctaaat
    38281 gatttaggac ttccttttat aatttgctaa ggcattttat aggagattac ttttcttttt
    38341 gttaaaataa aaagaaatag ttgcattatt tgcatagaag aaagggatct gttatggttt
    38401 cagtgatgtg gtttcgtaga gatttaagga ttgatgatca aaaagcttta gctcatgcta
    38461 ttgctagtca atcaccaacc ttatgtgtgt ttcaatttaa caaggagcaa ttaaatctgc
    38521 tacatagtcg gaatcaatct agttttatta ctagcgtttt ggcttttaga aagttattaa
    38581 aatgtgaagg tattgactta tatctaatgt atggagactt aatgacctgt tttgagcaat
    38641 tattgacaca attaaaagac tggacagatg tgtattttaa ctatgatgaa tctggatatg
    38701 gtcgtttacg tgatcaaaaa gcagcacaat ttttcaaaaa aaatgggatt gctgttcata
    38761 cctaccaaga tcactattta catggtagtc aagagatcat taaccaatca ggtcagcctt
    38821 ataaagtttt tacgccctac tataggattt ggcaaaatta tccgaaagag actcctatta
    38881 aagtagaact atcgcaaggc aggtggttaa atcttgagac accagatgat gttttaagga
    38941 ctgttgagag ttttaaagat gaaaaatatc aggatgttgc aacttttgat gaagcgtcaa
    39001 aacaactaaa tcgatttatt caagaccaat tagcagctta tcacgctaat cgagattttc
    39061 cagcgcagct agggacgagt cggttgtctc cttttttaag aataggagct attggcattc
    39121 gcacggtata tcacgctgtg cgtcaagcac caaatagtct agggcaagct acttttttaa
    39181 aagaattagc ttggagagac ttttacaata tggtctatgt ggcttatcct gatcagaaaa
    39241 ctcagcctat ccaaaaagcc ttttctcaaa tcgaatgggt taataatcct gactggtttc
    39301 agttgtggaa agaaggtaaa acgggttacc ctattgtcga tgctgcaatg cttcagttac
    39361 aaaagacagg atggatgcat aatcgtttac gaatgatagt agcttctttt ttaactaaag
    39421 atcttttatg tgattggcgt ttaggagagc agtattttca acaacaacta attgattatg
    39481 atgctgccag taatatcgga ggatggcagt gggctgcttc cactggaaca gatgctgttc
    39541 cttattttag aatatttaat cctgttactc aaggtaagcg ctttgatcct aaaggcgagt
    39601 ttattaaagc gtatttgcct caactagaac acgttccaga gaagtatctc cacgaaccgt
    39661 ggaagatgcc aaaaaacctt caagagagtg tgtcctgtat tattggcaca gactatcctc
    39721 aaccaattgt cgatcatgct aaacaacgtg aacaagctat tgcaaagtat gagtgggcaa
    39781 aagaaaaagc aaaaatagaa tgactgttct cattataaga gtttaaacaa aaagttatca
    39841 tgaattaaga ttatttaatt taaaaaataa gttgacttta tttagattat ttgatactat
    39901 tcagttgtct cccttagaga aagcgatttc ttgttttgga gctgattttt accatttggt
    39961 cttagaatag gatgagtaat atgacttaca acgaggtata tcaagaatgg ttgcacaata
    40021 atgatcttag tgatgatatt aaagcagatt tagcagccat aaaagacaat gaggctgaga
    40081 ttcaagatcg tttttacaaa acacttgaat ttggaacagc agggctaaga ggaaaacttg
    40141 gagcaggcac caatcgcatg aatacctata tggttggtaa ggcagcacaa gctttagcta
    40201 atactattat tgatcatgga cctgaagcgg ttaaaaaggg cattgcggtt agttatgatg
    40261 ttcgctatca atctagaaca tttgcagaat taacatgctc tattatggca gctaacggta
    40321 ttaaggcgta cctttataaa gggattcggc caacaccaat gtgttcgtac gctattcgtg
    40381 ctttgggatg tatttctggt gttatgatta cggctagtca caatccccaa gcttacaatg
    40441 gttacaaagc ttattggcaa gaaggttctc aaattttgga tgacattgcg gatcaaattg
    40501 cacaacacat ggctgcacta actcagtatc aggaaatcaa acaaatgcct tttgaaaagg
    40561 ctctggacag tggacttgtt acttatattg atgagagtat tgaagaagca tataaaaaag
    40621 aagtgcttgg tttaacgatt aatgatactg acattgataa gtcagtccga gtagtctata
    40681 cccctttaaa tggtgttggg aatctaccag tgcgtgaggt tttaagacgc cgcggttttg
    40741 aaaatgttta tgtggtacct gagcaggaaa tgcccgatcc tgattttaca acagttggct
    40801 atcctaatcc cgaagtccct aaaacttttg catattcaga aaaattaggt aaggcagttg
    40861 atgctgatat tttgattgca actgatccag attgtgaccg tgtggcttta gaagttaaaa
    40921 atgcagtcgg tgactatgtt tttctcaatg gcaataaaat cggagcgctt ttatcttact
    40981 atatcttttc acaacgattt gacttaggca atttaccggc taatcctgtt ttagtgaaat
    41041 ccattgtaac aggagacttg tcacgggcta ttgctagcca ttatggtatt gaaaccgttg
    41101 aaacattgac tggttttaag aatatttgtg gcaaggcaaa cgaatatgat gtgacgaaac
    41161 aaaaaaacta cctgtttggt tatgaagaaa gtattggttt ttgctatggc acttttgttc
    41221 gtgacaaaga cgctgttagc gcctctatga tgattgtaga aatggcagct tactacaaga
    41281 aaaaagggca gaatttacta gatgttttgc agactattta tgcgacattt gggtattata
    41341 atgaacgtca aattgccttg gagcttgagg ggatagaagg acaaaaacgc attgcgagga
    41401 taatggaaga tttcagacag acaccaatag ctagtgttgc agagatggcg ttagacaaga
    41461 caattgattt tattgatggc tatcaagatt ttccaaagca aaactgtctc aaattttatt
    41521 tggatgatgg ttcttggtat gcacttagac catcaggaac agagcctaaa ataaaatttt
    41581 atttatatac tattggccaa acacaagaaa atagtgcaac aaaattagat gctattgaag
    41641 cagcgtgtcg cacaaaaata aatcaggtta attaaacatc aaaaatggat aacactttta
    41701 cactattttt ccatataaac aactacaaaa ggaggtgaga cttttaggca ccttcttttt
    41761 cttgtaggtg ccactaatca atttaatcga ctcaaaccaa tactaaaaaa taagtaagag
    41821 tataaagaac aggcatctat ttttttgtta taatagaaaa atgaaattaa agggagatgt
    41881 caatgacaga actaattgat ggtaaagcct tagctcaaaa gatgcaacaa gagttagcag
    41941 ctaaagtcaa caatctaaaa caaaaaaaag gaattgtacc aggcttagcc gttattcttg
    42001 taggtgatga tcctgctagt caggtgtatg tccgtaataa agagcgtgca gctcttactg
    42061 taggttttaa aagtgagacc gttagattat cagaattcat ttgtcaagaa gagcttattg
    42121 cagtaatcga acgttacaat gcagataaca ctattcatgg tattttagtg cagctacccc
    42181 tgccaaatca tattaatgat aaaaaaatta ttctcgccat tgatcccaaa aaagatgtgg
    42241 atggttttca cccgatgaat acaggtcacc tttggtcagg acgtcccttg atggttcctt
    42301 gtactccatc agggattatg gaattgcttc gagaatataa tgttaacctt gaaggtaaac
    42361 atgccgtcat tattggcaga tcgaatatcg ttggaaaacc aatggcacag ctcttactgg
    42421 acaaaaatgc aacagtcacg ttgacacatt caagaacacg tcaattagaa gaagtatgtc
    42481 gctgtgcaga tgtgttgatt gtggcaatcg gacaaggtca tttcataaca aaacaatata
    42541 taaaagatgg tgcgatagtg attgatgtag gaatgaaccg tgatgataat ggcaagctaa
    42601 ttggagatgt ggcctttgat gaggtggcag aagttgcagc gaaaatcacc cctgtaccag
    42661 gaggtgtcgg tcctatgacg attgctatgt tgctagagca aacttatcaa tctgctctcc
    42721 gtagtactca taaatagtta taattagaca attcaacata agagaatata agaagtcagc
    42781 aatggcttcc ttttttgttt ttctgctcac tatttattca gaaaaatggt ataattgcat
    42841 tagtatgcaa agggactatg tcaggtccaa ctaagtgaaa ggtggcttga tggcagatta
    42901 tttaaccgtc actcatttga cgaaatattt aaaattaaaa tttgaccgtg acccttattt
    42961 ggaacgggtt tatctgactg gtcaagtgtc caattttcga aaacgaccaa ctcatcaata
    43021 tttttcctta aaagatgaaa gtgctgtgat tcaagccacc atgtgggcag gagtctataa
    43081 aaaactagga ttcgacctag aagaaggcat gaaaattaat gtaattgggc gagtccaact
    43141 ttatgaacct agtggctctt actctatcgt gattgaaaag gcagagccag atggtatagg
    43201 tgccttggct ttgcagtttg aacaattaaa gaaaaaatta acggcagaag gttattttga
    43261 gcaaaaacac aagcagccct tgccacagtt tgtatcaaaa attggggtca ttacaagtcc
    43321 tagtggtgct gtgattcgag atattatcac aaccgtttca cggcgttttc caggggttga
    43381 gattttatta ttcccaacta aagtacaagg tgatggagcc gcccaagaag tagtggctaa
    43441 tattcgaaga gccaatcaaa gagaggattt ggacttgctc attgtcggcc gtggaggtgg
    43501 ctcgatagaa gacctttggg ccttcaacga ggaaatagtg gttcaggcta tctttgaatc
    43561 gcaacttcca gtgatttcga gtgtgggtca tgaaacagac acgactttag cggattttgt
    43621 ggcagatcgc agagcagcca caccaacagc agcagcagag ttagcaacgc ctattacaaa
    43681 aacagatctt atgtcttgga tagtagagcg gcaaaatcgt tcctatcagg cctgcttgag
    43741 gcggattaag caacggcaag agtgggtgga taaactctcg caatctgtta tttttaggca
    43801 accagaacga ttatatgatg cctacctgca aaaaattgat cgccttagca tgaccctgat
    43861 gaatacgatg aaagatcgtc tgagttccgc caaagaaaac aaggttcagt tggaccatgc
    43921 cttggccaat agtcaattac agacaaaaat cgagcgatac caagaccgtg ttgctaccgc
    43981 taagcgttta ctgatggcta atatggctag tcaatatgat agtcagctgg ctcgctttga
    44041 aaaagcacag gatgctttgc tatcactgga tgccagccga attatcgccc gtggttatgc
    44101 aatgattgaa aaaaatcaag cactggtagc ctctgtaagt cagataacaa agggtgatca
    44161 gttaaccatt aagatgcgtg atggacaatt agatgtagag gtaaaagatg tcaaaaacga
    44221 aaacatttga agaaaattta caagatttag agactattgt gaacaaactt gaaaatgggg
    44281 atgtcccttt ggaagaagct atttcagaat ttcaaaaagg aatgcttctc tcaaaagaac
    44341 ttcaaaagac cttacaagcg gcagaaaaaa cactcgtcaa agtgatgcaa gctgatggca
    44401 cagaagtaga tatggatgat taatggacaa attagctaga attgacgaag ccattcgtcg
    44461 ctactataag acgactagta acggtgtatc tgaagagttg attgatgcta tcttgtattc
    44521 tgttgacagt ggtggcaagc gcattcgccc acttatctta ttagagatga ttgagggatt
    44581 tggggtatcg ttacagaatg ctcattttga tttggctgca gctcttgaaa tgattcatac
    44641 aggaagtctg attcacgatg atttgccagc catggataat gatgattacc gacgtggcag
    44701 actgaccaat cacaaacaat ttggagaagc cacggccatt ttggcgggag acagcttatt
    44761 tttagacccc tttgggttaa tagctcaagc tgaattaaat agtgaggtta aagtagcctt
    44821 aatccaagaa ctttccctag cttcaggaac ttttggcatg gttggtggtc agatgttaga
    44881 tatgaaaggg gaaaatcaag cattaagtct tcctcagttg tcactgattc acctcaataa
    44941 aaccggaaaa ttattagctt ttccttttaa agcagcagct cttataacag aacaggctat
    45001 gactgttcgt caacaactag agcaagcggg aatgctcatc gggcacgcct ttcagattag
    45061 ggatgatatt ttagacgtga cagctagctt tgaagatctt ggaaaaacgc ctaaaaagga
    45121 cttattcgca gaaaaagcta cttatccaag tttactgggg ttagaagcct cttaccaact
    45181 gctgacagag agtttagatc aggctttgac gatttttcag acactagaaa gcgatgtagg
    45241 ctttaagcct caaataatta caaaactgat agaagggtta cgacttaatg cctaaagaaa
    45301 gagtagatgt gttagcctat aagcaaggat tatttgagac cagagagcaa gctaagcgtg
    45361 gtgtcatggc aggcttagtg gtctctgtga ttaatggcca acgctatgac aagccaggtg
    45421 acaaaattga cgatgggact gagttaaaac ttaaaggtga aaaactcaaa tacgtcagtc
    45481 gtggtggatt aaaactggaa aaggggctgc acgtttttgg tgtatcagtt gctaatcaaa
    45541 ttgggattga tattggcgct tcaacaggtg gttttaccga tgttatgtta caagatgggg
    45601 ccaaactagt ctatgccgtc gacgttggga ctaaccagtt ggtatggaaa ctcagacaag
    45661 atccacgagt aagaagtatg gaacagtata actttcgtta tgctcagcca gaagacttta
    45721 atgagggaca gcctgtattt gccagtattg atgtgtcctt tatttctctc agcttgattt
    45781 tgccagccct gcataacgtt ttgtcagatc agggacaggt tattgctctc attaaaccgc
    45841 aatttgaagc tgggcgcgag cagattggta aaaaaggcat cgtcaaggac aaacagattc
    45901 atgaaaaagt gattcaaaag gtcatggatt ttgcctcagg ttacggattt acagttaagg
    45961 gacttgattt ttctcctatt cagggtggtc atggcaatat cgaattttta gctcatcttg
    46021 ctaagtcaca gacacctgaa acgttagccc cgcatttgat tcagaaagtt gttgccaagg
    46081 cacataagga gtttgagaaa catgaaaaag agtgaacgac ttgaattaat caaaaaaatg
    46141 gttttgacgc atccaattga gacgcaacat gacctcttaa gattattggc agagcatggg
    46201 ttagaattaa cccaggctac tatttcaaga gacatgaatg aaattggtat agtaaagatt
    46261 ccttctggca gtggacgtta catctatggt ctttctcaag atagtggaaa aaagatcgtt
    46321 caaggaccta gatcgataaa gagcactatt ttagctgtat ctgacaaaac aaaaggttta
    46381 gaacaacacc tctatttaaa agtcgtacct ggcaatagta aattaatcaa acgttattta
    46441 ttagcagatt tttcaaaagc tatttttagt cttattgctg atgatgatag tttattgtta
    46501 attgcaaagt ctccttcaga agcagatatg atacgccaag aaattttgct ttggatgcag
    46561 ggtataacct agaaaaaaat aggggagaaa gtgatgttat tagaaatttc tattaaaaat
    46621 tttgctatta ttgatgaaat ttccctaaat tttgaaaatg gtatgacggt tttgacgggt
    46681 gaaactggag caggaaagtc tattatcatt gatgctatga atatgatgct tggtgcgcgt
    46741 gctagtacag aagtgattcg tcgtggagct aataaagcag aaattgaggg gttcttttcg
    46801 gtagatgcta ccccagaact ggttgcgtgt ctggaatcat caggtattgc tatggaagaa
    46861 gaactgatta ttcgccgaga tatctttgcc aatggcagaa gcgtgagccg cattaatggt
    46921 cagatggtta acctagccac cttaaaacag gtcggacagt ttttggtaga tattcatggg
    46981 caacatgacc aagaagaatt aatgcgacca cagctccacc agcaaatttt ggacgctttt
    47041 ggtgataagg cttttgagca attgaaagag aattatcagc ttatttttga tcgttataaa
    47101 agcttgcgtc gccaggttat tgacaaacaa aaaaatgaaa aggaacacaa agatcgtatt
    47161 gatatgttgg cctttcagat agcagaaatt gaagctgctg ccttgagtcg aggtgaggac
    47221 gaccggttaa atcaagaacg tgatcgctta atgaaccaca aacaaattgc tgataccctg
    47281 accaatgcct acgtcatgct agataatgac gatttttcaa gtctatccaa tattcgctct
    47341 agcatgaatg acttactatc aattgagcag tttgattcag agtacaaagg gatgtcgact
    47401 tcgatttctg aagcctatta tattcttgaa gaagtgagca agcaattatc agataccatt
    47461 gaccaactgg attttgatgg tgggcgatta caggaaattg aatttcgctt ggatatactc
    47521 aatagcttaa ctcgtaaata cggtggtaat gtgaatgatg tgcttgacta ctacgataat
    47581 atcgtcaaag aataccagct attaacagga gatgacttgt cttcagggga tctagaggca
    47641 gaattgaaaa gcttggaaaa acaattggtt gctgctgctt cggagttaag tgtctctcgc
    47701 catcaattgg cggagcaatt agaagctgag attaaagctg aacttaagga actttatatg
    47761 gaaaaagcag atttcaaagt tcactttacc acatcaaaat ttaatcgtga tggtaatgaa
    47821 agcttggaat tttacatctc tactaatcca ggcgaaggat tcaagcccct tgtcaaggtg
    47881 gcttctggag gagagttatc acgccttatg ttagccatca aggctgctat ttctagaaaa
    47941 gaagataaga cgagtattgt ttttgatgaa gtagatacag gtgtttctgg tcgcgttgcg
    48001 caagccattg cccaaaaaat ttataaaatt gggcgacatg ggcaagttct cgctatttca
    48061 cacttacctc aagttattgc tattgctgat tatcagtatt ttatttctaa agaaagtaaa
    48121 gaagagtcca ccgtttctaa ggtaaggtta ttaactcctg aagaacgtgt ggaagaaatt
    48181 gctagcatga ttgcaggaac agatatgaca caagctgctc ttacgcaggc tcgtgaacta
    48241 cttgccaaac attaagatta tgtttggtat ttgatatttt cataattaga tgacattgat
    48301 tttttaggtg ctaaaataat cattgtgcta gaccattttt cctctgttaa tctggcttgg
    48361 tttgccttga caaacctctg agaaatagta gaatagataa gagaatttta agctgagggg
    48421 atagaaatga ctagtaaaaa agcgtgttta tcaagcatca ttgtgttagc aagtttaacg
    48481 tgtggaaatg atactgttag tgccaatcat ctctcagcaa ctggagataa gtttgatgat
    48541 tgctcaacac ttgttgaaaa agatgtggcc cctaaagatg aacttgagat gttagcatgg
    48601 tcctcgtctc aaacaactga tgatgctgac agagactatg aagattttct cgatgatgat
    48661 tcttttattt ctcaaaatga aactgataag atgtttgaga atttaactga tgataggtta
    48721 ttaaatgaat tagatgaatt agatgaagaa aatgaagaag atgaagaaga tacaattgag
    48781 ccagagcaaa atgtaataat gcctagtgac gatgagctat ttgatttaac tgatgctgtt
    48841 gagacacgcc ttactgtttc tagtgctccc catttagagg ctgaattgcc gaaaccacat
    48901 ttgaggagcc tatcagatac agcactgcgg tctggtgaaa ttagaggaca tttagataac
    48961 aaactggacg ctttgtctgt aacagctaca aagttagcat taacgatggc tcaaaaattt
    49021 gatttgacaa cgcatgtcta ttctataggt gaaagcttta gtgaagtatt agctgctcat
    49081 tatgaagaca gaaaagcaga atcagctttt tctaagaaaa agagatttca ccttcctatt
    49141 gctactccag atgttgttat agaggagtta aggcgcctag tctcttctat tggaagttca
    49201 aaagaagatg tttcagttcc ttatagtcgg aagctaggta tggcagttgc aaaaagaaaa
    49261 atagccctgc cacaaacggg agaggggttc tcttattatc cagttttact tggtttaatg
    49321 atattaggat taacgccgat tatgatacca aagaagataa ataattaggt aataagttat
    49381 tgtagttgta aaagacgggg caaatgttca agcgtgaaaa ggttgacttt tgcctcgttt
    49441 tgtatctcgt tattgctaag gcattttctt cgagcagcta gtgctcgcca tacctatcta
    49501 ccgagtgatt attcaatagc actaccagtt ttgctttatt tagtaaggag tgttagaata
    49561 aagaggtgag aaactagttt agaatggaaa aatacatggg aactataaaa attgttacag
    49621 attcatcaat aactattgaa ccagaattaa ttaaagcttt agatattact gtagtacctt
    49681 tatctgtcat gattgatagc aaattatatt ctgataatga tttaaaagaa gaaggtcatt
    49741 ttttgagcct tatgaaggct agcaaatccc ttcccaaaac cagtcagcca ccggttggtc
    49801 tctttgctga aacttacgaa aatttggtca aaaaaggagt aactgacatt gttgctattc
    49861 acctctcacc agctttatca ggtactattg aagcttcccg tcagggggct gaaatcgctg
    49921 aggcacctgt tacagtttta gattcaggat ttactgatca agccatgaaa tttcaggtcg
    49981 ttgaggcagc aaagatggca aaagcgggtg ctagtttgaa tgagattttg gctgctgttc
    50041 aagctatcaa atcaaaaaca gagctctaca ttggtgtatc taccttagaa aatttagtaa
    50101 aaggaggtcg tattggtcgt gtgacgggtg ttttgagctc gctacttaat gtcaaagttg
    50161 ttatggcact taaaaatgat gagttaaaaa cgcttgtcaa aggtcgaggt aataaaacat
    50221 ttacgaaatg gttagatagt tacctcgcta aaaatagtca tcgcccgatt gcagagatag
    50281 ctatttctta tgctggtgaa gctagcctgg cattaacctt aaaagaaaga atcgcagctt
    50341 attacaacca ctctatttcg gttttagaaa caggctctat catccaaaca catacaggag
    50401 aaggagcttt tgcggttatg gttcgttatg aataatcgtc atttatttag tgggatattt
    50461 ttctttgtta ttagtttatg tctggccttt ttattgctaa atattattat ccctaagtca
    50521 aattcacgtt tgaaaaagag tgattttctg aaaaaagaac aagtagctat ccaatatgtt
    50581 gctataggag attcattgac agaaggagta ggtgatctaa ctcatcaagg tggttttgtt
    50641 cctttgttaa cgaatgatct cagtgaatat tttaaggcta atgttaatca tcaaaattac
    50701 ggcgtatctg gtgataccag tcaacaaatt cttgatagga tgataaaaca aaagcagata
    50761 cagttatctt taaaaaaagc agatataatg acgttaaccg ttggtggtaa tgatgttatg
    50821 gcagttattc ggaagaattt agcggatttg caagtttcta gttttagaaa gccagctcgt
    50881 cagtatcaaa aacgattaag acagattatc gagttagcca gaaaagataa taaagatctt
    50941 cctattttta ttttaggcat ctataatccg ttttatttga attttccaga actaactgat
    51001 atgcaaaaag tgattgatga ctggaatacc aaaactaagg aggttgttgg agaatacgat
    51061 cgtgtgtact ttgtgccaat aaatgacctc ttgtataaag ggataaatgg acaagaagga
    51121 attgttcatt cttcaggaga tcaaactaca attgtcaatg atgccttgtt tactggggac
    51181 cattttcacc caaataatac tggctatcaa atcatgtcaa atgcagtaat ggagaaaatt
    51241 aaaaagcatg aaaaaaaaat caaaccttaa ttggtggaag tggagcttct tatgtctgct
    51301 tgcttttaat accgcctttt tgatggttat tgcaagtcgt ctcattcaag taagagaacc
    51361 tgagtcagaa ctgattgcta aaaaaccagt taaaaatatc aaaattggta catttgttac
    51421 aaccagagaa cagcttaacg aaactgtagc aagttatctt aaagattatc agactgaaaa
    51481 aatgtcttat aaattttatg cgacatcttc ttctattttg tttgaaggaa cttatcaatt
    51541 attagggtat gaagtccctt tatatatcta ttttcaacct catcgtctag aaaatggagc
    51601 tgtccaacta caggtgatct ctttttcagt gggaactctg ccactcccag aaaaagatgt
    51661 tttgcagtat ttgaaatcaa gctacaaatt gccaagcttt gttaaagtga tgccaaatca
    51721 atcagctatc gttgttaatt tacaagatat ccaaaatgat gctaaggttt atttaaaagc
    51781 caagaaaatt gatttattta atgatgaaat cagttttaac atctataaga aataagctca
    51841 aataacgtta aatacttgac ctaatcgctt tttttagata tgataatatc tgttaaagca
    51901 ttaagcttac taattatttg gaggatttgt taaatggcta acaaacaaga tttaatcgca
    51961 aaggttgcag aagcaactga attgactaaa aaagattcag cagcagcagt tgatgccgtg
    52021 ttttctacaa tcgaagcttt ccttgctgaa ggtgaaaaag tacaattgat cggttttggt
    52081 aacttcgaag tacgcgaacg tgcagctcgt aaaggtcgta acccacaaac tggtgcagaa
    52141 attgaaattg cagcttcaaa agttccagcc ttcaaagctg gtaaagctct taaagacgct
    52201 gttaaataat tgcatagata aaagcccatt gtatcaagcg ttccagcctg tgcagtgggc
    52261 ttttttgtgt tcaggggggt aaaaaagggg taaaaaattt aatagttttc cataatatca
    52321 gctacacttg atttcatttt ctttgtgaca tgcgtataaa tttgggcagt agttttagcg
    52381 tctgcatgtc ctacacgttc catgattgat tttagcggca cgttattctc tgctagacgg
    52441 ctaataagag tgtgacggaa gatgtggcta gtaagttttt ttgtaattgg gtcttccaat
    52501 ctttcattag ctttttttaa agctaagttg aatgagttag tctgaattgg aacaccgttt
    52561 tttgttgtaa aaaggtatcc catatctcta tatctatgat ttgtattttt ttctagttcg
    52621 ttcataaatt ctaactcttg tagaatttca agttctctac ttgtcatgat ggtttcacga
    52681 taagaagcta atgtctttgg tgctgtcttt tccccgttac gatatccttc tgtatgatca
    52741 aatgttccgt gcaactgcaa tattcttgac ttagattcgt agttgcacgg ctcaatgctg
    52801 acagcttcac cgatacgaca accgttcaaa ctgataaact cagccaacaa accaagacgg
    52861 taagtgctag gtcttctgta caattctttc aataatggtt taatttcatc ttcttcaaga
    52921 tatttttctt cagccttttt ccagtcttca agagttttct ttacccttgg gagtttagca
    52981 cgtcttgcag gattatctta gataatatcc aaaccaacag cataatcaaa tgctaagttt
    53041 agcatagact tattacgctc ttttttattc ctagagcaat ctaggttatc gagataattc
    53101 tgaacgtatt taggatcaat attcactact ttaacaccta ttccaaaagt ttcccttatc
    53161 tcttcgatgt tacccctcag agaagctaca gacgaccttt taagttcttt cttataaaac
    53221 gcccaccatt catctaaaag ttccgtgaaa agtaactcag aggcctttaa ttgcgctatt
    53281 ttttctgtta ttttttgttc aaggattttt cgagctgctt tataagctct tgaattatcc
    53341 ttctccatag taacggatac aggtttccat gttccagtgt aaggatcttt ataattttca
    53401 cgaaatttga atttaccgtt atcagtttct tctatccaca tttgtttttt acctcatttt
    53461 ttgttaaaat gagtataaga aaacgaccta tttaatggtt gtttcttata ctagatccgc
    53521 ctcacgctcg caccgaccaa agttgaacgt gtggcttttt tattttactt gattttctca
    53581 aataccattg tagcttgtat tctatctccg ccaccaaatc ctttactgcc accatttgat
    53641 gtggtaatag tgtgtaggcg atatcctttt tttgcttgct tattaataac attttcaagt
    53701 tcagttaaat ttcctgagcc tgttcctata agcttttctt ttagtgtaac ttgtagcaca
    53761 acatattcat aattttcgcc agaagcagtt gaaacagtac tagcttcttt tacattgtcc
    53821 aaaaatccca tgataatctc ctttaaccta ttaaagtata atattcatca ataaccatga
    53881 cttcatcggt cgtggtcttt aaattatgtc tttgcataaa agacaagtag ttaaactcat
    53941 gtttgtcttc tactttgtca aattcatctt caagcaaaca cctgatcata tgtctatttg
    54001 cctgcaattc aaattcttca tgacgccttt gatattggcc agaatcatgt tcaatatgtc
    54061 ctagttcatg aaaaataact ttcttttttg actcatcgga taatgctcta ttaacgaaga
    54121 caacttttat ttcatcaata tagattcctg gacgtggcca tagttcatta tcgaaataag
    54181 ctaattctac attatggaag tctaaaatct cctcaatagt catagactat cttcccttca
    54241 agtaaatttc aataatattt tgtattgctt caatatctga ttcagtaagc ggcttaccat
    54301 cgaacgtttt ggcgtttttg gccatttttc gtagatcttc agaagtgtat tcttggttat
    54361 cttttgcaat tgcagggtta tcagtgcgac caagcaagta atctgttgag acgtggaaat
    54421 agtctgcaat ctcttgtaat ttttcagaac ctggtttgtt tcgttttaaa gcatagatgg
    54481 tatttcgact ataccccatc ttttcttcta gagaatttat tgaaagacct tgttttttag
    54541 caagttcttt tatcctttca aatgttataa acactgattt atcaaccttt ctggaggatg
    54601 acaaaaaata ttttaaagaa tttcaataaa aaccgttgac tttttacgga gaatactcta
    54661 aaatagtttt tgtaagatag ttagttagta aaaaacgaag ttaaacattt tacaaatctt
    54721 tttaaagtag tt
//
LOCUS       DAUGJR010000007        54237 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUGJR010000007 DAUGJR010000000
VERSION     DAUGJR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54237
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.007"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(294..657)
                     /locus_tag="VH800_000411"
                     /pseudo
     CDS             complement(294..657)
                     /locus_tag="VH800_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1078..1611)
                     /locus_tag="VH800_000412"
     CDS             complement(1078..1611)
                     /locus_tag="VH800_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEQ8361505.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1691..2467)
                     /gene="recX"
                     /locus_tag="VH800_000413"
     CDS             complement(1691..2467)
                     /gene="recX"
                     /locus_tag="VH800_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEQ8361506.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2582..3937
                     /gene="rlmD"
                     /locus_tag="VH800_000414"
     CDS             2582..3937
                     /gene="rlmD"
                     /locus_tag="VH800_000414"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8361507.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIISKWYKQGYRADAVIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            4602..5957
                     /gene="rocA"
                     /locus_tag="VH800_000415"
     CDS             4602..5957
                     /gene="rocA"
                     /locus_tag="VH800_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEQ8361508.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRRLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLEVVDFTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQDDSQSVFAIPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(6058..8763)
                     /locus_tag="VH800_000416"
     CDS             complement(6058..8763)
                     /locus_tag="VH800_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEQ8361509.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKKYHFGQRFPKEVYQEAQEYLARLSQ
                     SFQIIDTSGQVRPEAEILGTSIAFDYDLPKRSFREPYFAIKVRLRLPITLPAMSWKTL
                     ALKLGNETTPSETVSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPNHDQPFYADQGTIKLNIISNTAQVAELEIQQTFAIPISADKLLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(8778..10064)
                     /locus_tag="VH800_000417"
     CDS             complement(8778..10064)
                     /locus_tag="VH800_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEQ8361510.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANEKGHQTDHTQMNPWIWERKYEIDCLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCTKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            10197..11237
                     /locus_tag="VH800_000418"
     CDS             10197..11237
                     /locus_tag="VH800_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8361511.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            11288..12982
                     /locus_tag="VH800_000419"
     CDS             11288..12982
                     /locus_tag="VH800_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8361512.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDTPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKISEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGNKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLAVAKEEGLDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQPGYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVAELVERVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            13006..14448
                     /locus_tag="VH800_000420"
     CDS             13006..14448
                     /locus_tag="VH800_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8361513.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDAIPVISPSWSPEWYYDPYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(15059..15937)
                     /locus_tag="VH800_000421"
     CDS             complement(15059..15937)
                     /locus_tag="VH800_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8361514.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            16133..17083
                     /locus_tag="VH800_000422"
     CDS             16133..17083
                     /locus_tag="VH800_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8361515.1"
                     /translation="MIRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            17093..18019
                     /locus_tag="VH800_000423"
     CDS             17093..18019
                     /locus_tag="VH800_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8361516.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            18100..19545
                     /locus_tag="VH800_000424"
     CDS             18100..19545
                     /locus_tag="VH800_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8361517.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            19851..20456
                     /locus_tag="VH800_000425"
     CDS             19851..20456
                     /locus_tag="VH800_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEQ8361518.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            20446..22170
                     /locus_tag="VH800_000426"
     CDS             20446..22170
                     /locus_tag="VH800_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8361519.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADKVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESVADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDYLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            22170..23654
                     /locus_tag="VH800_000427"
     CDS             22170..23654
                     /locus_tag="VH800_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8361520.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDCILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLIYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            23584..27090
                     /locus_tag="VH800_000428"
     CDS             23584..27090
                     /locus_tag="VH800_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEQ8361521.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWITAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYADGKDYDRLHEEHSDWLLYGSET
                     VSAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLQVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKASTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSLVKKAFSMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            27228..28106
                     /locus_tag="VH800_000429"
     CDS             27228..28106
                     /locus_tag="VH800_000429"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8361522.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            28341..29096
                     /locus_tag="VH800_000430"
     CDS             28341..29096
                     /locus_tag="VH800_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEQ8361523.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQASALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            29149..29487
                     /locus_tag="VH800_000431"
     CDS             29149..29487
                     /locus_tag="VH800_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8361524.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            29489..29794
                     /locus_tag="VH800_000432"
     CDS             29489..29794
                     /locus_tag="VH800_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8361525.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(30229..31302)
                     /locus_tag="VH800_000433"
     CDS             complement(30229..31302)
                     /locus_tag="VH800_000433"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEQ8361526.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(31358..32110)
                     /locus_tag="VH800_000434"
     CDS             complement(31358..32110)
                     /locus_tag="VH800_000434"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEQ8361527.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(32352..32422)
                     /locus_tag="VH800_000435"
     tRNA            complement(32352..32422)
                     /locus_tag="VH800_000435"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32388..32390),aa:Thr,seq:ggt)
     gene            32589..32843
                     /locus_tag="VH800_000436"
     CDS             32589..32843
                     /locus_tag="VH800_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEQ8361528.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            32861..33256
                     /locus_tag="VH800_000437"
     CDS             32861..33256
                     /locus_tag="VH800_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEQ8361529.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            33541..33860
                     /locus_tag="VH800_000438"
                     /pseudo
     CDS             33541..33860
                     /locus_tag="VH800_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264372.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            33857..34420
                     /locus_tag="VH800_000439"
     CDS             33857..34420
                     /locus_tag="VH800_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8361530.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTQLTAAETAQLIIQKMTHIKEN"
     gene            34422..37070
                     /locus_tag="VH800_000440"
     CDS             34422..37070
                     /locus_tag="VH800_000440"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEQ8361531.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDDWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEDAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFNSNINYIKCFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            37224..39632
                     /locus_tag="VH800_000441"
     CDS             37224..39632
                     /locus_tag="VH800_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEQ8361532.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKTKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGVSHFLS
                     AKDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSA
                     SFYF"
     gene            39765..40493
                     /gene="cas5c"
                     /locus_tag="VH800_000442"
     CDS             39765..40493
                     /gene="cas5c"
                     /locus_tag="VH800_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEQ8361533.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            40493..42388
                     /gene="cas8c"
                     /locus_tag="VH800_000443"
     CDS             40493..42388
                     /gene="cas8c"
                     /locus_tag="VH800_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEQ8361534.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QIQYDSFHKQLNNWIDYCEEGDVKKFLTFVQQFILKPEFLTLILDSLIGPDYQHNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEEDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            42393..43241
                     /gene="cas7c"
                     /locus_tag="VH800_000444"
     CDS             42393..43241
                     /gene="cas7c"
                     /locus_tag="VH800_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEQ8361535.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTL
                     EILEGL"
     gene            43243..43917
                     /gene="cas4"
                     /locus_tag="VH800_000445"
     CDS             43243..43917
                     /gene="cas4"
                     /locus_tag="VH800_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEQ8361536.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            43914..44939
                     /gene="cas1c"
                     /locus_tag="VH800_000446"
     CDS             43914..44939
                     /gene="cas1c"
                     /locus_tag="VH800_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8361537.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSSVLVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            44950..45243
                     /gene="cas2"
                     /locus_tag="VH800_000447"
     CDS             44950..45243
                     /gene="cas2"
                     /locus_tag="VH800_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8361538.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   45392..45686
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45459..45489
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaa"
     gene            45846..46556
                     /gene="ccdA2"
                     /locus_tag="VH800_000448"
     CDS             45846..46556
                     /gene="ccdA2"
                     /locus_tag="VH800_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEQ8361539.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            46569..47192
                     /locus_tag="VH800_000449"
     CDS             46569..47192
                     /locus_tag="VH800_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEQ8361540.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            47235..48341
                     /gene="msrB"
                     /locus_tag="VH800_000450"
     CDS             47235..48341
                     /gene="msrB"
                     /locus_tag="VH800_000450"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8361541.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKSDMEAKGYGYLLSSVE"
     gene            48429..49169
                     /locus_tag="VH800_000451"
     CDS             48429..49169
                     /locus_tag="VH800_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8361542.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            49166..50899
                     /locus_tag="VH800_000452"
     CDS             49166..50899
                     /locus_tag="VH800_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8361543.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSS
                     KKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLVLRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMH
                     ELMADDTQENE"
     gene            50972..52051
                     /locus_tag="VH800_000453"
     CDS             50972..52051
                     /locus_tag="VH800_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEQ8361544.1"
                     /translation="MSLATDYFSRQTPIVEKLMAYGFEKRDNGYFYNERFMEGEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEATP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            52065..52781
                     /locus_tag="VH800_000454"
     CDS             52065..52781
                     /locus_tag="VH800_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEQ8361545.1"
                     /translation="MVEFVADQSFWELFPGAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(52947..53420)
                     /locus_tag="VH800_000455"
     CDS             complement(52947..53420)
                     /locus_tag="VH800_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8361546.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            53562..>54237
                     /locus_tag="VH800_000456"
     CDS             53562..>54237
                     /locus_tag="VH800_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8361547.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYT"
BASE COUNT        16282 a         9944 c        11764 g        16247 t
ORIGIN      
        1 gctatttagt aactttggtt aaagtaatcg aactaacttg gttgattgta ttttaatgat
       61 aaaaagctta aatttgttgt ataacaaatt taagcttttt attgtttatt tttaattgca
      121 gattggggtt taaaagacac tttacaatgc tctcaagtca tgtgttgttg taggttgtat
      181 gcatatatta caaatcccat tataaaagaa attgtttaat taatggatag taatggatgg
      241 tatggagatc ttaatgtggt tttaatggta attttagcag ttatagtaag acaaaaggtg
      301 acttggaaaa gtttatgcag acgattctta actcccacaa tatcttctgt cagattttat
      361 tagacttctt ctcagtgtca tttttgtctg ttttacgaac gtgcaggcta ttcaattgct
      421 tcttagtttc taaaggatta aaccgagtat aagcgtagcc attatctgcg aaaaaacctg
      481 aagacgacga gaatagacat taatcgtttt aaggataatc tcagggttat ggacggtttt
      541 caagtttcca agaagatgat tgaggccgat ggtatcgttt tgtcttgaat gattccttat
      601 tttagtggtt tcattttcaa tacacgacgt caagcgtcct acatactttg ataaaattct
      661 acctaaaaga ggtgtcttgt cagttttggt tacaacatca agtgccaaaa gactttgcga
      721 cttaacaaga cacttctact ttaacgcaaa gaaaaagtag tgagtactct ctttcgtcgg
      781 agatttcctc gctactaaac ttagtatttt ttgatacttt ccttaggtag tgcttaaggc
      841 agcgactttc tttggaattc catgccttat ttttgagatc ctaggctcaa aaatgccaag
      901 tggcgtcaac attaacattg acgccacttt taccacaacg aaaaacatct gttttggctc
      961 actccacacg cagaaatagg aaattggatg tcaaatcagc agagctgttc atgctttttg
     1021 agcctaaaac tgagtttgtc tgcgttctga gcactccttg ggagtgctgg acaactctta
     1081 acgattcttc agttcaagat aacgtttgta ccaaatagtg atataggcct tggaaaatgg
     1141 tcctttttca tgattaatcc aatcaaccaa tattttgaca ttttctttta ggataaagtc
     1201 catatcggct gaatactgca tctctttttt atgaatctcg tattcatcaa catcaagtaa
     1261 tctcttttca ccatccgcaa agactttgac atctaaatcg taatcaatgt atttaagggc
     1321 ctcagtgtcc atcatgtatg gactagctaa gttacagtaa taagagacgc cattatctcg
     1381 aatcatggct ataatgttaa accagtattt tttatgaaag taaacgattg caggttcgcg
     1441 ggtcacccat cgtctaccgt cactttctgt gacaagagtg tgatcattaa ctccaatgag
     1501 ggcattttca gttgttttta gtaccatagt atcgcgccaa gtacggtgca aactaccatc
     1561 atgcttataa ctttgaattg taataaagtc gccttcttta ggtaatttca tgccttacca
     1621 actttctaca attaaactta tcctctatag tctatcataa atgtgtgaaa aaatcacttc
     1681 ttttgtcagt ctataaataa tttcttaact tgcaattaat gtcgtcgctg ttgtagcctt
     1741 ttcggtagag agcctgatag agcttttgct ttaaggtata accatcatat ttgcgactga
     1801 gtttacgata ttgtttgtct aattctttgt caagaagatc ttctatttct tgattatctt
     1861 ggtcaaaatt aaggtgattg aggctatgtt tagctagatc gtatgaaaag cctttggtca
     1921 gtaatgcttg ggtgatttta tctttcaagg cttttggtgg caatttttct tgatatttgt
     1981 caaagagttt ttggcttact ttttgagcga gttggctaaa gtcagtttga gataagatag
     2041 gatcaatgtc atgacttgca atgccttttt gtaataattt ttgttttaag acttggggac
     2101 ctttatcacc atttaactga ttttggcgaa tgtaggtatc agccaatttg gtgtcgtcta
     2161 tccattgttc ttcttggagt tgagtgatga tgtcagcaat aatgtgttct tcaatctcat
     2221 gcttgcgcag gtaatcagca acttgcttgt tgctgcgttg ttgaaaggaa agaaaataaa
     2281 gggctaaatt tttgccgtag gacagttggg caaaatgttt catgtcttca agctgatcat
     2341 tgtcaaggac tttatcttta ctcaacataa accgaacaat agtatcttct gttacataaa
     2401 gggattcgtc attatccaat tcgataaggt agaggcgttt tttcttttca attttagtga
     2461 ttttcatact ttgattatat caaaaatggt aaaatagaag acgaaaatac tgctaaaaat
     2521 gtgttgcttg tgagtgcttt tggtggtgag attaggatac tagaggaagt aaggggaaga
     2581 gatggtcgta aaggttaaac agaaaattcc tttaaaaatt aagcgaatgg gaattaacgg
     2641 tgaggggatt ggtttttatc agaaaacttt ggtatttgtc cctggtgctt taaagggaga
     2701 agatattttt tgccaaatca cggcggttaa acggaatttt gcagaggcca aactgttaac
     2761 ggtaaacaag gcttctaaga atcgtgtcaa accagcttgt tctgtttatg aaacttgtgg
     2821 tggttgccaa atcatgcatc tagcctatcc taaacagcta gatttcaaag atgatgtgat
     2881 taggcaggcc cttaaaaagt tcaaaccaac tggctatgaa caatttgaga ttagaccgac
     2941 tttaggaatg aaaaagccag atcactatcg ggccaaattg cagtttcagc tgcggtcatt
     3001 tggcgggacg gtcaaggctg gtttattttc ccagggaagt catcgcttgg ttcctattga
     3061 caattgcttg gtacaggatc aactaacgca agatattatc aataagatta cgcagttagt
     3121 ggacaagtac aagttgccca tttacaatga gcgcaagatt gctgggattc ggacgataat
     3181 ggttcgtaag gcacaggcta gtgatcaggt acagattatt gttgtgagta gcaaagaagt
     3241 taggttagcg aatttcattg gcgaattgac taaggcattt cctcaggtta aaacggttgc
     3301 cttgaatagt aatcgttcta aatcgagtga gatttatggg gacgaaacgg aaattctatg
     3361 gggacaagag gcgattcatg aagaagtttt agactatgga tttgcgttat caccgagagc
     3421 tttttaccaa cttaatccac agcagacaga agttttgtat ggtgaggtgg tgaaggcctt
     3481 ggatgtaggg agcaaagatc atattattga tgcctattgt ggggttggct cgattggctt
     3541 tgcttttgca gggaaggtca agtctgtgcg ggggatggat attatcccag aagcgattga
     3601 agatgcacaa aaaaatgcca aagccatggg ctttgacaac gcttactatg aggcagggaa
     3661 ggcagaggat attatttcta aatggtataa acaaggttac cgcgcggatg ccgtcattgt
     3721 ggacccgcca agaactggtt tagatgataa attattaaaa acgattcttc attaccagcc
     3781 taaacagatg gtttatgtgt cttgtaatac ctccactttg gcccgcgact tggtgcagct
     3841 aacaaaggtt tacgatgttc actatatcca aagtgtagac atgttccccc atacagctag
     3901 gaccgaggct gtcgtgaagt tacaaaaacg tgtatgattg agtggcaata acaactcaag
     3961 ttttataagc tcaggtaatg ggtttgagca atagcttgac atagtaggga tgtcaaaaac
     4021 ggtttactaa gcatagtcat attattgata actctatgtt tattttagaa acattcatgg
     4081 ttaaaaaagt ttgttagttt gtcactaagt agggtctatt tgaagagcaa gtacacacag
     4141 acaatattag gataattggt tgttgaaaaa aagctgtttt ttgctataaa ttagaaaact
     4201 gagtggtcag gaggttacat taccagaagt tattttagta tgctaatatg aacgatgata
     4261 tagaggattt atcctgattt aatcttttaa gctgtaagaa acctttgcaa aaactgtagg
     4321 ctgtgtgagt ctttatgtgt tagatattaa agataaatgc aacacttttt tataatgaga
     4381 tcaacaactg ataaatctga gttgataacc agtaaaatga tcggaatgta gaaaagttac
     4441 ttaatcaagc ttttcgtaat ttaactgtta gaatgacaga acttatgata aaataaagaa
     4501 tatgattaaa atgaaaaagc tcagtttatc tattacggag ttcgaaatga aaagaaaatc
     4561 gagatgtgat aacatatttt gaacgagaag gagaaggata aatgttagaa gattttcttc
     4621 aatttttagg atttatattt ttagatatta ttgaaattat gttaacgtta aagcttttta
     4681 gctttgtaag tgcaattccg cttcgcctga aaaatatttt ttatttatca cttagtatgg
     4741 ttttgtttca agtagttttt tgggctttct ttccagacca tttcattctt gatgttgtga
     4801 tgttggctca gtttcttttc tttgcgctta tagccctata ctatggtaaa tcaataaaag
     4861 ctaagttttt aatgttttat gccttttttc cactagtgtc tattagtttg gttaagcgat
     4921 ttattgtatt ttttgttatg ccattgtttg gtatgcctta ttcagttgtt aaacataata
     4981 cactactgat ttacagcatt acttgtttta gtattttttt gatttatcgc tgcattcaag
     5041 tttttcattt cgatttttca acctggcgcc aatattttca atcacataga gctagtaaac
     5101 tattagtgtt tactaactct tcgatggctc tatattactt gtgtgtccaa gggatagatg
     5161 tgatgtcgcc ttctttatca ggacttgcta caacgactgc tcgttcaatc atagtgctct
     5221 tttatttcat tttgtttctt actttattaa ttcatttaga gcgttatgta aaacaaaact
     5281 ctattgaggc aattgtgcaa caaaaagaat atcgtgagct gattaattat agtcagcacc
     5341 ttggattgct gtatcaagat attcaagagc ttaggcggct attaactacc gtgtctagtc
     5401 gtcttaagat tggaatcgaa caaaatgata tctctattgt gagacttact tatgaaggta
     5461 tcttgaatgc tgaaaagaat aatgctaaag atgacagact tgatttaact tgtttagata
     5521 aattacaagt tgaagcaatc agacatattg ttttagctaa attaattgag gcaaaaaata
     5581 agaagcttaa ggttgaggta tcgatcccta attgtattgc aacgtttttt ctagaagtag
     5641 tagatttcac taagctattg tcatttttgt tagataatgc tatagaaatg agtttggaga
     5701 caaagcaacc ttgcttatca atagcatttc tggatcaaaa ccataaactt gtcatagtca
     5761 ttcaaagcag tactaaacaa ggacaagatg atagtcaaag cgtgtttgct ataccggctt
     5821 tgaaaaaaag agatgactgg caatttgact taaggaatgt cacgaccatt ttaaatcgtt
     5881 atgactatct cacaattagc tcgcagattc atgatggcat tttaacccag ttaatagaaa
     5941 tagctaagcc tgactgatgt taaaggtatg aataatcact caaaatcaac ttaagagtct
     6001 gagacaatag tcccagactc tttttgaata tgttaatcta ttactaatga taatagttta
     6061 ttgtttcttc caagctagag ttaaaatttc cgctttgcca agttggctgg gtgtgctttg
     6121 cttgctgtct ttttctaaca aattagtgac cttggcattg tagtttggca ggcttaggct
     6181 aaagtcacaa gttttatcgt ttgagagatt atagctgcgc gtgataaggg cattgtctgc
     6241 taagcgacgt ttgaaagctg tgagggcaac ttggtcgttt gtacccgtca aatagctata
     6301 ttctgcggct aatgttccct cgtgttggtt tgtttgtgtg gtaataacag ggacttggcc
     6361 ttcttgagct cgccagtagc tggcaaattg tgtttgctta gtgatgcttt caaaactata
     6421 agaaaggctg tgtttgccaa gacactgggc ttcaggtgtt gggaagtaac cccagtcgcc
     6481 catttcgcca acagaacgta agagagtgat ggcaatggtg ttggtatctg gtaagatctc
     6541 atattcgttg aggccatagt taccaatagt gactccattt tcaccatcaa agagactcac
     6601 aaagcattct tggtgctgtg ggttacttgg attcttccaa aaggtggcat ctggatgatt
     6661 tggacgtttg acagtttcaa aaatactgtc agctagatga tggtctgttt taaggtgcgt
     6721 tgggaatagg acgcgcaagc gatgattagt catttggtta tcaaaacgtg tggtgaattg
     6781 gaggcgagga ttatttttct ccatgcggat aagggttgtt aaggttagct cagccttttc
     6841 ttgtgaacgt cttgcttggc gttctgtgat gtcaatgaca gcctccatct cagcctgtaa
     6901 gagcttatct gcggagatag gaatggcaaa ggtttgctgg atttcaagtt cagcaacttg
     6961 agcggtgttg ctaatgatgt taagcttgat ggtcccttga tccgcataga aaggttggtc
     7021 atgatttggc tggcgagaaa tatattcatt tccaatatcg ccacaatctt caaaccgcaa
     7081 caggtcttga tagattagtc cagattgttt atcggtgatg gttagacgac catcggtttg
     7141 tatcataact tttagaaacc cattttcaag gcactgatta ctgtcatcgt agagggaaac
     7201 ggtttctgaa ggagttgttt catttcctag ctttaatgct aaggttttcc aagacatggc
     7261 tgggagagtt attggtagcc gtaatctcac tttgatggcg aaataaggtt cgcggaagga
     7321 tctcttgggc aaatcgtagt caaaagcgat gcttgtgcct aaaatttctg cttcgggtct
     7381 cacttgtcca ctagtgtcaa taatttggaa agattgggag agtcttgcca aatattcttg
     7441 agcttcttgg taaacctctt taggaaagcg ttggccaaaa tgatattttt tccaggtcag
     7501 gctgagctca gcaacacttg ttttggaatg gccgctggta ttaaataaga cgaagggttg
     7561 gctatccatt ggaaaatccc tggtatcaat ggcgtcagca atttgcttag cagcttcttt
     7621 tgctaaatag tgtccgactt cataggcttt ttcaaagcgc gtcatcattt cccgatgaac
     7681 gctatcaaca ctacaaccac agatagaatc atgagggtga ttttgcatga gggttttcca
     7741 agcgtaacgc agttggtcgt gagggtaggt acttgttacc tcataagcca ttgctgctaa
     7801 gggttcggtg atgttttcga gttggcgaga gactctggta ttagcctgtt tgaggtaaat
     7861 acgagcagaa gccgtgttag ctagggtata ccagccatcg gtttcttgac tggtaatctc
     7921 tccttggacg gttgaaaggt tctctggtaa atcatctgcg agatcagcca agtaatcttc
     7981 aaagcaggaa tgcacaaatt cgtagtcagg atagagttgg ttggctaagg cgattgcctt
     8041 ggtgacatca agttgtacgg gttgatgatc acacccgttc atcatcagaa ggtgcttggt
     8101 tgaggcgaag cgttcggcat cagcaagttt tttatcccaa aaaagacgcg cctcagcttc
     8161 tgttgtcggg atctcattgc cattgctgta ccagttggcg aagaggagtc caagaatacg
     8221 actgttatct gggccttgcc aactgatttc agagaattgg gagctgtatt tttcactggt
     8281 atccacctga ttgttaaatc cagttggacg aatgccacga ccaaaggcag cagcttgtag
     8341 gccggctttt aacatcagct gtggtgtttg tcccatattt ccaaaggtat caggaaaata
     8401 accaagtggc acactagcgc cccatctgtc acaatcttcc ttaccaatca gcatattgcg
     8461 cacattggat tcactgctgg tcaaaaaatc gtcctgtaag atatagaaag gtccgatacg
     8521 gagttttccc gaagcaatgg cttgtctaat ctcaggttct cgttcggggc gtacttttaa
     8581 ataatcatct aggataatgg tttgcccatc caaatgaaaa ctatgaaaat caggatccgt
     8641 ttgaaaaact tctaacaggt catctattaa gttaatcaga cgcatgtggt gttgttcgta
     8701 agccatgtac cactcgcgat cccagtgact gtgtgaaata atatgtactt ttttagttgc
     8761 catagtggcc tcactttcta aggagcaata ctaaagccca gatagtcaag aagtagttca
     8821 cagaacatca tgttagccca agagaaccac tcacgagtgt attgataagg atcattgaca
     8881 tcgaaaccct cgtgcattaa gtgggtacca gcatctgttg ccacaagcaa atcaagcatc
     8941 tcttttttac tgtcttggtc aagagcggtc aatccttgta aggcaagggc gatatgccag
     9001 atataatttt ctggtgtatg ggaagaaccg atgcctgctg ctgcatttcc ctgataataa
     9061 taagggtttt cttggctgag aatggtgcgg cgcgttgcca gatagatagg gtcatcttta
     9121 gtgcaaaaac caaggtaagg tgcagcaagg aggcttggaa tattagcatc atccatgatg
     9181 gaaaactgtc ccagaccatc cacttcataa gcgtaaatgg tttctccctt gctgttttga
     9241 acaagggcat ggtctgcaat acccgattga atagcttctt tcagctgctt ggcacgagta
     9301 gctactggtt cattgtgaaa aaggttgtta tataaatctt ctagatagga aagcacaacc
     9361 actgcaaaca tatttgaagg aatgaggtaa ccatattgac aagcatcatc acttggtcta
     9421 aagcctgacc aggtcatccc tgttggtgcg acaggacttc cttttccagc atgtgttagg
     9481 gtatcttctt tgcgccaagt atcgcgttca aacaagtaag gggactgggc gtggtcttgc
     9541 tcaactgtcc ataggtcaag aatgagttct accccacgat gaaaatcgtc attaaactga
     9601 tcggtgcttc ctgtttcacg atagagcaga taagccagtt gaatagggta gcaaaggcaa
     9661 tcaatctcat atttgcgttc ccaaatccaa gggttcattt gggtatgatc tgtttggtgt
     9721 cctttttcgt tagcttcttc gttgaaggca ttggcatagg gatcgataca aatgtagcgg
     9781 aattggcgtt tgaccagacc ggcaataatc tttctaattt cttcatcttc cttggcgagg
     9841 aagaggtaag gtttcatttg cgcagtggaa tcacgtaacc acatggcagg aatatcgcca
     9901 gttaaaagaa agctagtgcc atcttcgtag gtttttaggg ttgtctctaa ggtattggta
     9961 aagctggttt tgaaattaag agcccaatca gggtgttggt ctccacaaag gctttccacc
    10021 ttggccataa attggctgac gctagttggg attggtcgtg tcatgtcata tcctccaaaa
    10081 tgatatatca tttatcttcg gtttcattat aaatgataag ttaaactttg tctataggtt
    10141 tttgaaaagg tttacaactc ttttttgaca tgttatactg ataacaggag taaagaatga
    10201 caaaattatt atacaaaaag atatatcatt tcattaaaga gcagatagca tcaggtcgtt
    10261 tgcaaattgg tgaccgccta cctactgaaa aagaattgtc agaacagttc tcggttagcc
    10321 gtatcacttc taagcgagcg cttgtagaac tggagcaaga aggcttgatt acgagaagtc
    10381 gtgggaaagg aagcttcgta gctaaaaagc aagtgacgtc ccctgaagcg aataaggatt
    10441 tattgttgat tcttcctttt gcttctgatt atgaattggg agattatgct aagggaatta
    10501 tgacctccat tgctgaaaca ggttaccgtc tcatggttca attggccagt acagtaaggt
    10561 tagacaccct gtcagactat gctgggatta tttattatcc tgaagatgtc aatcacagta
    10621 ttgatttcct gttttactgc gaccatcatc acattcctct agtcttgttg gataaatctc
    10681 tagatctttt tcagtttccg tctgttgtag cggataataa aggcggtgcc tgtcaattga
    10741 ctcagcactt gattgagcaa ggctgtgacc agattagttt tgtggcaaca ggctcttttg
    10801 gagaagtatc atccgttaga gaccgttatt tgggttactt agcggcaatg gcagaatcgt
    10861 ctctaaaatc ccattatttt cctaagacag agactgaaac aacagatgct tatttggacc
    10921 gtttggtgaa aaccttatcg gagacgacag ccactaaaag ggggcttgtc gtggaaaacg
    10981 attggttggc tattcagctg attcaaaaaa tcacacaggt aggcttatct attcctgatc
    11041 aagtcgctat tgtaggcttt gataatagtc aagcctcccg tttgttgagt cccaaattaa
    11101 gcacagcagc tcaagatttt taccaaatgg ggcaagaagc agctaaagtc ttgttgcaga
    11161 ttattcatga gccagaccaa gcagtggtgt cttgccagtt acctgttcaa gtatttatca
    11221 gagaaagtag tcactaaaaa agacgttact agcatgagct ggttagctca ggtaaaggag
    11281 accagaaatg accatttatc acgccttaaa ggattatcaa gaagtcatga caagaggaga
    11341 ctatcttgtc tttgacacgc cattgacttg ccgatttatt ggccgttttt tccgctttga
    11401 aaatcaaaaa gccctgctgg cagaattggc aacgtcaaag tattttcagt ggattgaaga
    11461 aggccaagca gaggtgacga tgaaacactt ttttaaccgt cagctggcta aggatgcctt
    11521 taccctgaag atttcagaag ataaggaaat cattattgaa agccaaaacc ttagaggttt
    11581 tcgttacgcc caagaagctt tgcttaaagt catgaccttc aaaggggata aactttattt
    11641 gcccattgtt tctgtcaagc acagcccttc ttttgctatg cgggggataa ttgaaggctt
    11701 ttacggaaca ccgtggacac gagaagagcg gttagattgc ctgcgtttta ttggaaataa
    11761 aaggatgaat acttacatgt atgctcctaa agatgatgat taccaacgaa aactgtggcg
    11821 cgatctttat cctgaggatt gggtgactta tttcaaagag ctacttgcag tagccaagga
    11881 agaagggctt gatttttggt atatgattag tccggggctt gattttgatt ataccaagga
    11941 agctgactat cagttgctct atcaaaaatt gcaacaactt ctagcgttag gtgtttgtca
    12001 ttttgggctt ttgctggatg atattgacta ccaaattgta gatgctgttg agagacgatt
    12061 caaaaagact gcctatgccc aggcccactt ggcaactgag gttcatcact ttttaaacca
    12121 acaacatgcg gcgccagaat tggtgatctg tccgacagaa tacgacaacc accatgattc
    12181 tatctatttg caagagctgt cagaaaggat tcctaaagaa gtcgcctttt tctggacagg
    12241 cccaagcacg ctagcgagtc aaatctcgca agcagatatt gaaactatgg cagcagtata
    12301 tcaacggcct atcattattt gggacaatat tcctgttaat gattatcaaa aagatccaga
    12361 acgtctcttt ttaacccctt ttgccaatcg ctcgccattt ttatgccagc caggctatca
    12421 ggtcaagggg attgtttcta accctatgat tagttgggaa ttatctaagc ttaccttgac
    12481 agatatgagc cattatctgt gggatgctaa ccgttatcag cctagtcatt cttggctaga
    12541 aaccttaaca gactatacag aagatactga attagcctta gctttacagg catttgcttg
    12601 gcataatggc aatcgtcatc tgcacaggga ccttcctttt gaagtggaag aagctctcct
    12661 ggctaaggat gtatcaacgt tatcagcttg ggtagctgaa ttggtcgaac gtgtcaatac
    12721 gttgagaaag ctagataagc cagcgtttca acaagctatt gctccttggt ttgaacgggt
    12781 ggccaaagac caagattttt ggcaggctat gttaaatcag gagcctcagt tggaaacact
    12841 ctatgctgac ttacaagaag ataaacaccg tattggaagt gacattccaa gtcgttacta
    12901 tcgcatctac tatcaacagc aagataaact aacagctaat caaggtcaag ttacccaagc
    12961 aagaccggaa gactatgctt agcatacgag ctagaaagga atgatatgtt agcatttcca
    13021 aaagagtttt ggtggggagg agccacctca ggccctcaaa gtgaggggcg ttttgctaag
    13081 cagcaccgca atctctttga ttattggtat gaagaggagc ctgacttgtt ttacgattac
    13141 gtgggacctg atacggcttc ggatgcctat catcagattg aatctgattt gaccttgtta
    13201 gcttcactag gtcacaattc ttaccgtacc tccattcagt ggacacgttt gattgatgac
    13261 tttgagcaag cgacgattaa tcctgatggc cttgcctatt ataatcgagt gattgatgct
    13321 tgcttggcca atggtattcg tcctgttatt aatttgcatc attttgacct gccaattgcc
    13381 ctctatcaag cctatggtgg ctgggaatca aagcatgttg tggacttatt tgtcgccttt
    13441 agcaaggttt gttttgagca gtttggtgat cgggttaagg attggtttgt ccacaatgaa
    13501 cctatggtcg ttgtggaagg ctcttattta atgcaatttc attaccctgc tatcgtggat
    13561 gggaaaaaag cagtccaggt cgcctataat ctagccctag ccacagccaa ggttattcaa
    13621 gcttacaggc gaggtccagc agaacttagt gatgggcgta ttggaaccat tctcaatctg
    13681 acgccagcct acccagctag tcaatcagaa gcggatatgg ctgctgcgca ttttgcagaa
    13741 ctttggaaca atgacttgtt tatggaagct gctgttcatg ggaaattccc agaagaattg
    13801 gttgcggtat tgaaaaaaga tggggttttg tggcaatcaa cgccagaaga gttggctctt
    13861 attgctgaga atagagtgga ttatttggga ttgaattttt accaccctaa gcgcgtgaag
    13921 gctcctgatg ccattccagt gattagccca tcttggagtc ctgaatggta ttatgatccc
    13981 tacctgatgc ctggccgccg catgaacgtg gataaggggt gggagatcta tcctgaggct
    14041 gtctatgata ttgccatcaa gatgcgagac cattacgaca atattccttg gttcttatct
    14101 gaaaatggtg tagggatttc aggagaagac cgttaccgtg atgaaactgg tcagattcaa
    14161 gatgattatc gcatccaatt tttgaaagaa catttaacct atctccacaa aggaatagaa
    14221 gcaggctcga attgttttgg ttaccatgta tggacaccaa ttgatggctg gtcttggctc
    14281 aatgcctaca aaaaccgcta tggccttgtg gaaaataata tccataccca agtgcgacga
    14341 cctaaagctt cagcttattg gtttaaaaaa gtagctactc ataaccgctt gatttcatta
    14401 gaagtaatgg aggagtttgg aggctctgct tctcacctca gtgattgaac gtgtgaacgt
    14461 ctcctttgag acaagtgaat aatgatgtta ccaatgatta aacaagggcc tttttcctca
    14521 tgttaagagg atcgaggctc ttgtatttct ttggaaagtg ttggtatttg ccgaactaga
    14581 tataagcgtt ctgtctggtt tagcatcaac tacccatctt gtttaatttg actcttcaat
    14641 tctttagagt atcttggcta aggatgcttg tttttcatct tggtatttta ggattttctt
    14701 tcatattttt gggccagata aaagtccctt atggtttcta gtgactgttt gttatgtcac
    14761 tgtccacgat aaggggacta tatgagtgag ttattaagtg aggctttgct tattggcgat
    14821 aactagcata gcttctaata gctcgagcat taactgatga ccaattcctt taacagaagc
    14881 gtcagcaaca atgacatcaa caaagggacc aggcatcagg ctgtgttcat cagcagagag
    14941 tcatttaggc agaaagccag tatcgttgta gctaatcagc aatcctttta ggatgtcttt
    15001 gtagatgtca gaggcgatta gggacaatag gggataagag ggatttagcg gtccatggtt
    15061 aggcctcctt gtgttcttgg taaaaatcaa tggcagctcc cagaagatta gcttcgtttt
    15121 taaagtgaca aatagctaat tggggtctaa ggtcggagat ttcgacggct tggtagagtt
    15181 tgtctagttc agcttcaatc gctgacagta gaaagtcagc ttgggaaaca ccacccccga
    15241 ttaaaatcag ttgaggatca aaggcgtgtt gaatgttaaa aataccgatg gctaaacttt
    15301 ggagaaagac ctgcctttct ttgagtgcta ggggatctcc ttgttctgcg agggcaagga
    15361 cagctttgcc agtataatct tttccgttat tgacgattgc actatagcgc ttggccatat
    15421 ttaccactgt ccctaactga ctaaaggttt ggtagcggtc gttcatgatc atgaaaccaa
    15481 actcgccccc aaataagtgg gcaccatggt aaatcttgcc atcaatgacc aagcttcctc
    15541 caactccagt accaagaacg agcatggcta ggctactagc gccttttcct gcccctaagg
    15601 tagcttcagc taaggcggca caattggcat cattttcgat agaaataggg taatgtagcc
    15661 gttcttctaa ggcctcttgt attttaaaat ggtgaatgta gggaatagcg ctggcgcctt
    15721 cgataacccc cttttcttta ttgactgccc caggtgaact gatggcaata cctgagaaat
    15781 ggtaagcaga gtaacgagca acttcttggt cgagtaattg gtaaaacttt tccagactag
    15841 agggagtggg aaagctgctt tgctggctta attggccatt gtgacagagg gcaaatttaa
    15901 gggaagtgcc tcctatatca atacataaca agctcatgag gtgttctcct ttattatagt
    15961 agaatagacg atcatgtctc atcttagtat gacagattta agcaacaacg aaaaggcttt
    16021 ctaagtgatt ctatactttg tgttatcata cctataattt gttgctttca aataatgaaa
    16081 gcgcttgata tactgtaact ataacgtgat taacacaaag ggaggttggg aaatgataag
    16141 acaaaccaac aaaaagacat ccttttggaa aaatgtgatt aaataccggg ccttattatt
    16201 aatggtatta ccaggtttca tctggttcat ctttttcttt tatattccag ttttagccaa
    16261 tgtggttgct tttaaagatt ttcattattc agcagggggc tttatggaaa gtttgaagga
    16321 gagcccttgg gttggtttgg ctaacttcaa atacctcttt gcttccaaag atgcttggtt
    16381 gattaccaga aataccattg cttacaatgt gattttctta ctctttaatg ttttctttgc
    16441 gattgctttt gccattatca tgagtgagtt acgaaataag agaacggtta aggtctatca
    16501 caccatgtcc ttattgcctt atttcttatc atgggtggtt attgaatact ttgtttctgc
    16561 ctttttaaat acggataaag gtttcattaa tcagctcttg accggaagtg gagcagatcc
    16621 aatcaagtgg tattccaatc ccacttggtg gcccttgatt ttacttttca tgagtgtctg
    16681 gaaggggcta ggctacaata gcattatcta ctatgcttca gtcaaaggga tttctgatac
    16741 ttattatgaa gctgctatgg tggatggtgc aagcaaatgg caacaaatta ggaacatcac
    16801 cattccacaa ttattgccaa tgatgtctat cttattgatc attaatattg gtaatatttt
    16861 taaatctgat ttcggacttt tctacgttat tcctaagaat tcaggcccac tttatgacgt
    16921 gaccagtgtg ttagatacct atgtctacaa tgccttgact gctacaggag atattgggat
    16981 ggcatcggca gctagccttt atcagtcagt agttgggacc agcatcttgt tagtcaccaa
    17041 tgcgattgtt cgtcgcatgg accctgatgc agccttgttt taggaggaaa acatggagaa
    17101 aaagaaaaaa gtcgaaaagg ttaatgttag aacctttgat cgaaaaacca atgctatctt
    17161 taatattctg attggtctgt ttgccatctc ttgtatcatt ccttttatct tcgtgattat
    17221 tatttccttc actgatgaaa gttacttgat taatcatggg tatagttttt ttccagatgt
    17281 ctggtcaact aaggcttacc agtatatttt tcaaggagcc atgtcccata gaatcatgag
    17341 gtcatttggg atatccgtgt ttattacagt ggtgggaacc tttattaaca cgaccatgac
    17401 atcaacctat gcttatgcga tttcaagacc ttatttccca tacagacgtt tttttactgt
    17461 ttatgcactt atcaccatgc tctttgcacc agggatggtt gctaattact tggtggtcag
    17521 caatctcctt catttgaagg atacggtttg ggccttgatt ttaccaatgg ctctgggccc
    17581 atttggcatc ttggtcatga gaacgttctt taaaaagaca gttccagata gcattattga
    17641 gtcggctcgt atggatgggg ctagtgaatg gatgattttt atgaaaattg tcttaccatt
    17701 agctgttcca gggattgcca ccatcagttt attttctgcc ttaacttatt ggaatgattg
    17761 gtttaacgcc ttgctttatg tgcaaagtga gaatctttac ccaatgcagt acttactgat
    17821 gaaaattcag agcaacctac aggccttggc acaaaatgct ggcatgagtg cacaaatggc
    17881 agatagctta gcatcgctgc caaaagaatc agttcgtatg gctatcgtgg ttattgcaac
    17941 cttgccgatt gccttgactt acccattctt ccaaaagtac tttgtcggtg gtttgaccat
    18001 tggtggggtg aaggaatagg acttaaggaa ctggtcacaa gaccagattt tatctaatca
    18061 ttagtaacaa aagaaaacat tttttaggag gcttcactta tgaaaaagtg gcaaaaaatc
    18121 gtgtgtgtga ctggaactgt gcttgcagcg tctagtttag cagcctgcga aagcaagtca
    18181 gcatcaaagg atagtgatgt caaattattg atgtaccaag ttggtgacaa acctgataac
    18241 ttcgatgaat tgatgacaat tgctaacaag cgcatcaaag aaaaaacagg tgcaacggtt
    18301 gaccttcaat acatcggttg gggggactgg gatgataaaa tgagtaccat cattgcctct
    18361 ggtgaaaact acgacattgc ttttgccaat aattatgtgg tcaatgcaca aaaaggtgct
    18421 tttgctgatt tgacaacgtt aatgccaaaa tacgctaaga aaacgtataa aaacttagac
    18481 ccagcctata ttaaaggaaa tactattgac ggtaaactct atgccttccc agtagatgcc
    18541 aacgtttatg cccaacagat gctttctttc aataaagaac tagtggacaa atatggcctt
    18601 gacatttcaa acattaagtc ctatgcagat gctgaaaatg tcttgaaaca attccacgaa
    18661 aaagaaccaa atacagcagc ttttgctatt ggtcaagtct ttagtatgtc aggtgactat
    18721 gactacccat taaccaaaac ccaacccttt gctgtgaaaa ttgatgaagg caagccaacc
    18781 atcattaatc agtatgaaga tgagtccttt aaaaacaatc tccgcttgat gcacaaatgg
    18841 tataaagaag gtttgattcc aacagatgca gcgaccaata cagaaggtta tccccttgaa
    18901 ggaaacactt ggtttatgcg tgaagaaacc caaggtccta tggactatgg cgatactatc
    18961 ttgaccaatg ctgcaggaaa agacatcgtg tctcgtccat tgactaaacc gctaaaaacc
    19021 acatcacaag cacaaatggc aaactttgtg gtatcaagcg tatctaaaaa caaagaaaaa
    19081 gcagttgaag tcctttctct tcttaatagc gatcccgaat tgttaaatgg gcttgtttat
    19141 ggtgtcgaag gcaaagcttg ggaaaaaatt ggcgacaaga aaatcaaact gctcgatggc
    19201 tatcaaccaa aaatgcacat gggtgcttgg aatactggta acaataaaat cctttacact
    19261 caagaatctg ttactgacga catgattgct aaacgtgacc aatcaatcaa ggatgctaaa
    19321 gaatctccaa tccttggttt cactgttgac acaaaagtta tcaaaacgga attgtcaaat
    19381 atttcaaatg tcatgaaccg atataaagca agtatcaata ctggtacagt ggatcctgac
    19441 gaagcccttc caaaacttct tgcagacctc aaaggtgctg gttgggacaa ggtgcaaaaa
    19501 gaagttcaaa aacaattgga cgactttgta gctaaagaca agtaaggcat tcattttctt
    19561 gattataagt tgagggctgg gaaatctcag ctcttttctt ctgatgagtg gaaaaaacgg
    19621 atcatcaaat aagtggaagt tataaaggga gaaaaattaa tgtcaataat gttactactc
    19681 ttagtaaagc ggtttccaaa agcctataaa gtgtgctata ttagaagagt ctaaactatt
    19741 aatcagagta aaactaatac cagcatctta ctgggggtgc taaaactagt ctcgtagctg
    19801 ctggtccctg aaactgctat aagtgttaac aagaaaaaga ggactatcat atgaatggca
    19861 ttgaaaaaac ctgcttttta atttggaaaa tgatccaatt gaccctcatt tttcatctct
    19921 tgtccttagc tggactgatt gtgtttgggg tggggccagc ctggcaaacc attgtcaccc
    19981 tatttttaaa aacacctcaa gaagaaaacc actattcttt gaaaagggct gttcaacttt
    20041 ggaaatctta tttcaaagaa gctaatctaa gatttggtct ttttgccctg actttccttt
    20101 ttttaacctt taatttgcat tgggcagtac agtttccatc cttgttttgg tttaccgtgt
    20161 ctttcttgat tgtaatagcc atggtttggc taaccatgac ctatctttac atggtttttt
    20221 atgcagtgag ctatgagatt aacctttgga ataatatgaa attagccttt atcagcgtct
    20281 ttttaagttt caaatccttt ttactcatgc tgagtgtttt gttgggaatt accttagtga
    20341 cttggcaata caaaggtctt tatctctttt taaccttcgg agctctagtc ttttgcttgg
    20401 actttgtcac taaggctaat cgtcgactag tagatggagt gattgatgag tgttaaaaca
    20461 ttgggaaggt atgtgactaa ccactttaag cagggttttt tgattaatcg actgatgaaa
    20521 ttatatagcc tgctaattgt aagttttttc actttagcag ctattggctt gagcagttat
    20581 tctattagta gtacttataa aagggtggat gctgaggcgc agatgcgatt ggaggagact
    20641 ctaggtagat tgcagtcaca aaacgatatt accctacggg ttttagacca gttggttggc
    20701 cgttcagaag attaccataa tctctatcaa tacatgacgt taaccccaaa ccaatatttt
    20761 tcaaacgttt ttgaagactg ggaaaaagga aaagacacgg tcctattttc tgaagaggtg
    20821 aggcgtcttt ttgacttgta ccctgatgtg acttctatga ccctactgct agaggacagt
    20881 agtgcttatc tgtacgccga taaggtcatt aagacgggtc gtttgcttta tagcaagcct
    20941 gaaaaagtaa ccggaaatgt tttagttcgc tctattcgaa atccagaatc aggagatgtg
    21001 acaggtcgtc tttacctgac ctttgacaaa ccaccgactt tggtagagac acagcaggat
    21061 cactatttag ctacttttgc ttttgattac tatggccgca aactcttcca tcaaggaggt
    21121 cggagatttc ctcatttaga ggctgaggtt aaaaaggcta tcaaggcaga tcgggcagct
    21181 gatcttagta atcttagcaa ggcttatcgg atgcagtaca atcgctcggg agacctcttg
    21241 gcttatgtgg ctgtcagaaa atcctattta ttagcggaag ctgtcaggac agtttttgtg
    21301 tatggccttg tttctctact tttagcttgg ctgttattgc agttgctctt tagggttttc
    21361 cgaaattata tccagcaggt ttctgaaatt acggatactg ttgaaatggt tgcagcaggc
    21421 gatttgtctt taaccatcga caacagccac atggaattgg aactgtatca tatctcagaa
    21481 gccattaatc agatgttggc cagcattaaa gcttatattg acgaagttta tgtgttagag
    21541 gtagagcaac gagatgccca aatgagagct ctgcagtctc aaatcaaccc tcatttttta
    21601 tacaacacgt tagagtatat tcggatgtac gcccttagtt gtcaacaaga agaattagca
    21661 gatgtcattt atgcctttgc gagtctgctt cgcaacaata ttagccaaga taagatgacc
    21721 accttaaaag aagaactggc tttttgtgaa aagtacattt acctttatca aatgcggtat
    21781 ccagatagct tcgcttatca tgtaaaaatt gatgagagtg ttgctgactt agccattcct
    21841 aaatttgtca ttcaacctct cgttgaaaat tattttgtgc atgggattga ttatagtcgc
    21901 catgacaatg cactaagcat caaggcttta gatgagacgg attatctctt gattcaggtg
    21961 cttgataatg gacgtggtat tagtcaagag cgcttagcag atatggaaaa aaggcttcaa
    22021 gagcaccaaa caacaggcaa tagctctatt ggtttgcaaa atgtttacct ccgtctcttt
    22081 catcattttc gagacagggt ttcttggtcc atggctaagg agccaaatgg tggctttatc
    22141 attcaaatta ggattagaaa ggatgcttga tgtataaggt actattagtt gacgatgaat
    22201 acatgatttt acaagggctc accatgatta ttgattggca ggcacttgga tttgaagtgg
    22261 ttcaaacagc aagatcaggc aaggaagcct tagcctattt gactcagtac ccagtggatg
    22321 tcatgatttc agatgttacc atgcctggaa tgacaggact ggatttaata gaagcagcta
    22381 aaacctatca tcctcagcta caaaccttga ttttatctgg ttatcaagaa ttctcctatg
    22441 tgcaaaaggc tatggaatta gaaaccaagg ggtatttgtt aaaacctgtt gataaggcag
    22501 aattacaggc taaaatgaaa caatttaaag actggttgga tgcccagcag gcagaatcaa
    22561 tccggcaaga agcctatcat gacagccttt tgaccctttg gcttacagat gaattgagtg
    22621 agaaagaatt tcagcagtta agtcaaggct tgccagcggc tgctttaact ggttttacag
    22681 tgctgtattt ggactgtcaa gagtggcaag cagccatcga tgcttatttt gaacgagaag
    22741 gtcagccttt ttatctcaaa aaagaagaag ataagaaggt ttatctggct gtcctacttg
    22801 gtaaaactga tcaagccaag gcgtttacct atgatctaca aaagcgattc tcaagaaaca
    22861 tgcatcaact tattttggga gaaacagttg atgactggga aaatgtttat gaaagctaca
    22921 atcaggtgct taagagcctc ttttacaatt gtgaagtgtc accaattaga gcaaaagata
    22981 agtccaaaat tgaactacca gagtcccgtt tgcagttctt tgcttttaac aaggcgttga
    23041 tgattgggga cgaacctaca atcttgtcta aattagaagc tatttttgac gagatgaaga
    23101 ccttgaactt ttcaccagag gatgtgaagc atgtttcgtt cttgttgttt tctgacattt
    23161 atcgtcaatt tcccatttta gataaaatga cttatctgtc catggtaaaa actattcatg
    23221 acagccaatc cattgattgc attttgaggg aactaaaaaa agtgttggat gtcaccaatc
    23281 agaacaattc ccctgaaaaa cgctattcag atttagttag tgaaaccatt gattgcattc
    23341 gcaaggaata ccatcaagaa ttaactctta aagctatcgc tgataggtta catgtcaatg
    23401 gggtttattt agggcaatgc tttaaaaatg aaaccgagcg tagttttacc cagtacttaa
    23461 atcatgttag gattcaaaaa gcgcaacagt tattgattta caccaaccaa tccatcaatg
    23521 aaattgctta tgaaacaggt tacaatacca atcattattt tatcaagatg tttaaaaagt
    23581 tgaatggttt atcgccaaaa gagttcagag atcgttacaa ggacaattac caagccatca
    23641 agggcgacca gtaacgtcaa acaggagatt gatatgacac cagatagcaa ggagcagaca
    23701 gtgactggct accaatacca ctatattgat caagaaggaa gaaagcagcc ctttaatcaa
    23761 ggctggcgtt ttcttatggc agatgtggcg tgtgctcagg acccttcttt tgatgattcg
    23821 aactggcagg tgattcattt accacatgat ttcagtctta cgcagcctta cacaagaaat
    23881 ggtgaagctg aaagtgctta taaattaggt ggtgtcggtt ggtatcggca ttatctcgtg
    23941 ttagatgagg ttttagctgg ttgtcatgtt gccattactt ttgagggttc ctatatggaa
    24001 acggaaattt atgttaacgg gcaattcatt ggcaaacact taaatggcta tcaggaattt
    24061 acttatgata tctctgatgt tgtgactttt ggagctgaaa atcttctggc tgtccgggtt
    24121 gaaaacaagg ttcccagttc tcgttggtat tcaggcagtg gtctttatcg tgaagtgagt
    24181 ttgtctgttc ttccccagct tcattttgtg gcagaccagg tagcaatgac cttggctgat
    24241 actgctgtgc aggagaaagg gcaacagaaa gttgatttac gctttgccct caatcagtct
    24301 attcagactt gccactacca attgagcctc tgtttatggg aacaatcaca ttgctcaaaa
    24361 gacaagaaac tcctttatca agaaacagaa gtgcctctag ctgatttggc tttccaaaga
    24421 cagtatggtc ttacactgtc tttggaagaa ctccaattgt ggtcaccaga taatcctcac
    24481 ctctacgatt tagaactcac tctttactat caaggtcagg tcattgattg cttttgcctt
    24541 gaaactggtt ttcgtcagct gacttttatg gccaatcagg ggctttttgt gaatggcaga
    24601 gctgtcaaat taaagggagt ttgtttgcat catgaccaag gaggcctagg agcttgtgct
    24661 tacgaagatg ccctagccag acaattagtc ctgttgaaag acatgggggc taataccatt
    24721 cgtagcaccc ataacccaag tagtcccaaa cttaggcaac tagccaatcg tctcggcttt
    24781 tttgtgattg aagaagcctt tgacacctgg acctatgcca aaaatggaaa cgttaatgac
    24841 ttttcaaact atttccatca gactatcgga actgaaaatg caaactatct tcaaagagtg
    24901 aggtcacctg aaacgagctg ggcccagtat agtattgagg ccatggtctg gtctgccaag
    24961 aatgacccgt cagtgttgat gtggtcgatt ggtaatgaat tgatggaggg tttttcagcc
    25021 gatgtcagtc attacccaga gctgacaaga caaatgtgcc aatggattac tgctattgac
    25081 acctcacgtc ccattacctt tggggacaat aaattaaaag aagctgactt ttgctggcat
    25141 gaggaagtgt cgcaaatggc aactcttctt agtcaattag accatcctca gggactcatt
    25201 gggttaaact atgctgatgg aaaagactat gataggcttc atgaggagca ctctgattgg
    25261 ctgttgtatg gttctgaaac agtctcagcc attaccagca gggcttatta taaagagaca
    25321 aaaaaagttc ttgactccgg ttatcaccta acctcttatg atcatgctaa ggttgattgg
    25381 ggtgccttcg ctagccaggc ttggtatgat accattaccc gtgattttgt tgctggcgaa
    25441 tgcgtttgga caggctttga ttatttagga gaacctaccc cctggaacaa gatcgacagc
    25501 ggtgttgtag gcctttggcc ttctcctaaa aatgcctact ttggcatttt agacacggca
    25561 ggctttccaa aagatagcta ttatttttac caaagtcagt gggcgcaggg gcagaccacc
    25621 ttgcacctgt taccagtctg gcagaaggac cagctttgtt tcgatgagca gggattggtg
    25681 gaggttgtgg tttatagcaa tgctgccagt gtgcaactga tgtttgaaga tgagcagggc
    25741 aacttaacag attatggaag gaaggcattt catacttata gcacgccaac gggacacact
    25801 tatcagcttt accaaggagc tgacgctgct aagaatcctc acgagaacct ttacctgact
    25861 tggcgagtgc cctatcaaaa agggttgcta agggcagtgg cctacgacat ttctggtaaa
    25921 agcattccaa aaaccagtgg acgttctcag gttagaacct atggttcagt ggcaaagcta
    25981 tcttggaaag cctttgaagc acctattgac gctccttggg aattgcttta tctggattta
    26041 tcactcttgg atagccgagg tgaattggtc agccatgctc aagattggtt gcaggttcaa
    26101 gtagaaggac cagcccgttt gttggctctt gataatggga atccgactga ccacacccct
    26161 tatcaggagc ctctgcgcca ggcatatggg ggaaaattat tagccatttt agccctcact
    26221 ggagaggcgg gacacattaa ggtcacggca aaagcctcgc agcaacttag cagtgttttt
    26281 cagacacaag tagcctgccg tgcccccaaa gaacacttag tgacactacc tttagagaaa
    26341 tatcagttta aaaagagccg actgacaagt caacaagaaa ttggtcaatc ttgtctaaag
    26401 accacacaat tcctttctgt tttggagaac aaagacaccc agcaaaaagc aggtaaggct
    26461 agcacacctc acattcttat cactagttac cagcactatt tatctctgcc cttgcaggtt
    26521 tgttctcagg catttgattt taaaaaaggc gacgatatct tcttgcctca gtggctccaa
    26581 gtcaaagatg cccaaggttc tcttgtgaaa aaagcttttt caatgacgtg gtacctaaaa
    26641 gagaaaatct ttgccaagcc tattcttgtc acaggctatg tttcttgttt tgggcaatca
    26701 ataccggttg aggcaaggct taacctagca caagctagca aaagacggca ccaggatctc
    26761 agtttagtcg ccaagcaatc cctggccgca agtcaaaaaa ggctaactta ttgctaccaa
    26821 tatgatacgg tgcaagccat aggagccatt agcttgcaaa atcacacagg cacatctctt
    26881 agtgtttctg tggcaatcag ttatggtagt cagagctcta ttaagcaaga aaccttgatg
    26941 ctagctgata gccacttgag ccagttagaa gaggttattt tcttcgatga tattttgact
    27001 gttttgtatc tggcagtgac ccttgaagtc attgaaggac ctgacctaac tgaagacagt
    27061 attcaaattg gcctttggga tttagcatga agcatgagta aaagaagact tctttggcac
    27121 caggtctgat gaattctgta aaataaggta taataaaaaa caaataggcg tcctttatta
    27181 cgtgaaaggc gcctttacaa ggttgaaatg gaaagtgaga tttctaaatg tcagaacgtt
    27241 tatcaggcca caccctgttg gtctctttgc ttgctacccc tattcgtcat agtttgtctc
    27301 ccaaaatgca caatgaagcc tatgctaaac tggggctgga ttatgcctac cttgcttttg
    27361 aagtagggac agagcaatta gcagatgccg tgcaagggat tcgtgcctta ggaattcgtg
    27421 gctccaatgt gtctatgcca aataaagaag ctattttacc cttattggat gacttgtccc
    27481 cagctgctga gttggtcggt gcagtcaata cggttgtcaa taaggatggt aaaggacatc
    27541 tcgtggggca tattacagac ggtataggag cgctcagagc cttggctgac gaaggagtgt
    27601 cggtaaagaa caaaatcatt accctagcag gagttggtgg ggctgggaaa gctatcgctg
    27661 tccagctcgc ttttgacggc gccaaagagg ttcgtttgtt taaccgacaa gctacacgtc
    27721 taagtagcgt tcaaaagctt gtgacaaaac tgaaccagct aacaaggact aaagtaaccc
    27781 ttcaagactt ggaagatcag actgccttta aggaggccat cagggaatct catctattta
    27841 ttgatgctac aagtgtagga atgaagcctt tagaaaatct aagtttgatt accgaccccg
    27901 agctcattcg cccagacttg gtggtctttg acatcgtgta cagcccagca gaaaccaagt
    27961 tactagcctt tgcccgtcaa catggcgccc aaaaagtcat taatgggcta ggaatggtgc
    28021 tttatcaagg agcagaagct tttaaattaa tcactggtca agacatgcca gttgacgcta
    28081 ttaaacctct tttaggtgat gagtaacact ttttaagtaa gcttaattat gatatattaa
    28141 taagagatgg agcagtcatc atgggctgct aaaattcttt ttgcgagagc tgtttttaag
    28201 agcaaaaagc ttatttgaag agccttatcc ctaacgtgat acaagtcata gttcctttga
    28261 ggtctgccag ataacctacc gtttttttag aaaagaagct cttataaaag gaaaagttca
    28321 atgaataaag gagaatagca atggtaacaa aggaagttgg gcatgacttt ttagcacgtc
    28381 taggaaaaaa acgcttaaga cctggcggtg ttgaggcgac aaactggttg attgaacaag
    28441 gacaattctc tcaggattgt cacgttttag aggttgcctg caatcgctgc acgacagcaa
    28501 tagagttagc taaaaccttc ggttgtcaga ttgatgccgt tgacttaaac cccaaggttg
    28561 tcaaagaagc acaagaaagg gttgctgttg aggggttaac ccgtcacatt acagtatccc
    28621 aagccagtgc tttatcacta ccatttccag ataaccattt tgatattgtg attaatgaag
    28681 ccatgttaac catgttgaac gcccaagcca aggagaaggc actcaatgaa tattggcgtg
    28741 tgttaaaacc aggcgggcga cttttgacac atgacgtagc ttatgaagat ccaaaaacaa
    28801 gacaagtact tgacgagtta cgtcaaacga ttcatgtcaa tgttgctccc ttgtcactaa
    28861 caggttggca agccttatat caagaacacg gtttttctca agtgacttat caccatggga
    28921 aaatgtcttt gatgacacct cgtggaatga ttaaggatga aggtcttatg aacaccctga
    28981 acattatgag acgaggcctt aagaaagaga acagacaaca gtttttaaag atgcgtcgtt
    29041 tttttaccag aacaggcaaa aatctctgct atattgctgt aaaaagtgta aaataaacct
    29101 tagaccaacc tgtccataca actaaacaga ccatagagga gttcgaagat gtcttatatc
    29161 aataatattg agcacgcgaa ggttcttgat ttgacgcaag aagtaatgat tgagcaagat
    29221 caaatgttaa gtagaacact agtccaaagg caagacctag gaataacagt tttttcctta
    29281 gataagggcc aagaaattgg gcgacactca tcaccaggag atgccatggt tactatctta
    29341 agtggcttag cagaaatcac cattgatcaa gagacctacc gggttgctga aggtcaaacc
    29401 attgtgatgc cagctgggat tcctcatgcc ttatatgcag tagaagcctt tcaaatgctt
    29461 ttagtagtag taaaaccgga ggcttaacat gattgaaaat ctctctcaat tggtgcaata
    29521 tcatgatcat caggtggcta gccgatcctt gagccgtcta ctgggattat ctcaatctat
    29581 tgttttatat gccatggccc aaggagaaag cattagtcaa gagactagtc caagagataa
    29641 agtaatactt gttttagaag gtcagctcat tttcgattta gaggatcaaa aacaggtcct
    29701 aactcaagaa agtctcatag ccatacctgc ccaaaaagtc catcatttag aagctaaaac
    29761 cgattgtaaa ctattacaag tgcttttaga ttaagggctt attgtcaact gtattgggtg
    29821 gcctatggaa aagcaaaaga gaaggtgacg ctcatcttct ctttttacgt attcaaagcg
    29881 atgacaatac gaattttaaa gcttggcttt ctcatctcca gattaagccc tttagcttgg
    29941 tttattttag aattcactaa aaaaacctta atgagtttcc tatctcctta taggtttctc
    30001 attaaggctt tttagacgaa ataattgaac gacaggcaaa agaaagatct ttttacgagt
    30061 gataccgttc tcctatagtt ccataaatcc tctttttgat gttgctgtta gttattctta
    30121 gctaaaagtt atattgttat caagacttgt ctgtagtaac atgttttagg agttccagga
    30181 taccgttatt ctcttagcaa gcttaactag ctagagtgga gtcactattt ataataaact
    30241 gtcgagcttc tcgacaaatt ggtgatcgtc tttgttaatg gctagggtgg taaaaccggt
    30301 ttctgtgggt aatataaaga taatatgttg ctcagaattc ttcttatctg ttttaaagac
    30361 gtcaaagagg gatgtcgcag agacatcagc tctttcaagt gttgttggta actggtaacg
    30421 ttcaaaaact tgaaggaggc tatccaagtc ctcttttggc aagagtcctt tggaaacagc
    30481 cagtttagca tcaaccacca taccgatagc aatggcttca ccgtgatggt aaaaatcatg
    30541 gtggcagagc gattcaatcg cgtggcccaa ggtatgccca aaatttaaag acatgcgcaa
    30601 accattttca aattcatctt gttcaacaat ccgtttttta ttggaaatgg attggtaaat
    30661 cagacgttca agtccctgct tatcggtttc tttttgaaaa tcacgtaact gctgaaaaag
    30721 cggtctatca tgaatgaagc cgattttgag catctcactg atgccgcagg agaattcccg
    30781 ttgcggtaag gtctccaaaa aggtggttga aataatgata gcttctggag ggtaaatgct
    30841 gccaatcata ttggttagac ctttaaaatg gactccaact ttgcccccga tactgctatc
    30901 cacctgacta agtaaagtcg ttgggatttg aatgtaggga ataccacggt aataggttgc
    30961 agcgacaaaa ccacccagat ccccaacaac accaccacca atagtaacaa tcatatcttt
    31021 tttggaaaaa ttttcagcga tgagctggtc gtagatagca ctgacacgtt ccaaggattt
    31081 ggattgacct cccggagggc agacatggac aaaagcgttg tattgctgag caaattcttc
    31141 aaagagagtc tgatacaagt ggtagaccgt ttgatcggtg ataaacaaga gtttacgctg
    31201 cttgcgctca ccaaggcaat ctgctaaggt ttttaaaaca tggtcggtaa acaggatatc
    31261 ataatccttg acccgagaat ggacatgaag tgtttgtggc ataagcactc ctttcatcag
    31321 tactaggtaa cagagataac gcagtgatat ttagagctta atcttgccaa agttcctgcc
    31381 ccaactgttc taattgctta taatcaattt gctgggcagc atctgacagc gcatggtcgg
    31441 gatcaggatg aacctccatc atgatgccat tggcaccgac agccttcgct atcttagcag
    31501 caggtaagag taaatctcgt ctgcctgtcg aatgagatac gtccacaata atcggtaaat
    31561 ctgtcttttg ttgaataata gggactgcca taatatcaag catatttcta gtctccacat
    31621 cgtagccacg aacgccacgt tcgcataaga taatgttaga ttttccagtg tcttgtaagt
    31681 aggaaagggc gcccaaatat tcctcgatag tagccatcaa gcctcgttta aacaaaatag
    31741 gcttatcgat gtgtgacaag gtttttaaaa attcaaaatt ttgcatgttg cgggcaccaa
    31801 cctgaatgac atcgagatag tcataggctt cttctaattg gcgctcggac atgatttcac
    31861 tgaccgatag taagccaaat tcctgacaaa cctcatgcaa gtaacgaatt ccttgcaggc
    31921 caaggccttg aaaagaagca gcagatgttc ttggtttata ggcgcctcct ctaaaatagt
    31981 tgtaaccaag ttttttggca cttgaagctg ctaatctaat gtgatcataa gattcaatgg
    32041 aacaaggtcc aacaataaaa ttattcttag aacaagtctt attttgaaag tcagacataa
    32101 tgtcaatcat tcgtttgatt cctttactaa ttctgtatgg cgtgctctat gggataacgt
    32161 cttatttagg aatacaaaat ctcgttgtta tccatgaagc acccttagcc tgtgaaatga
    32221 taccataaac aagatgaaat agcaagtaaa ccctagattg tctatgttct tagtcatttt
    32281 tattaaaaaa ggcttactag ctataaaaaa atactgccct aaatcttatt aggacagtat
    32341 ttttttatag atgccaccac cgagaatcga actcggaacg aagcattacc attgctttat
    32401 tataccattt aactacagcg gctacctttt tataatacta taagttatta attgatgcaa
    32461 gcttttctta aaaatatttc cttaattgtt tatcatcaaa atgagggtac cagttattaa
    32521 taacatggca caagaggcct gccttatggt ataatggtaa agataatttc agaaagagga
    32581 agccaagcat gtcttatgaa aaagaatttt taaaagattt tgaagactgg gttaaaactc
    32641 agattcaagt caatcagcta gccatggcaa ccagtcaaga agttgcccaa gaagatggcg
    32701 atgaaagggc taaagatgcc tttattcgtt atgaaagtaa gttagacgcc tacgaatttt
    32761 tactaggtaa atttgacaat tataaaaatg gtaaagcctt tcacgatatt ccagatgagt
    32821 tatttggagc aaggcattat taagaaggag acacgaaata gtggcaaaac aaaaaaatcg
    32881 taaaaaagca ttgaaattag aaatgaagcg taatggcttg ttaaaaaaag caggtcaagt
    32941 ttttgataag gcagttgaaa gtgttgaaac agctgtggat aaaaccattt ctgctggtaa
    33001 aaatcttgtg gaaaaaggca gccaaacagt tgaaaacctg acagcaagca aggaaagact
    33061 tactcttgat gagtttgcag ggcagccagt tgtagctggt atccgctctg accttgtcga
    33121 aaccctatat gcagaaggca tccattcagc gcaagctttt aaggagtgga cagaaaaaga
    33181 cctccttgct cttaagggca ttggtccagc aacggttaaa aaattggtcg aaaatggtgc
    33241 aagctttaaa aaatagtcat cttctcgttg cttaatggct ataaatttgt tagaatatta
    33301 gcaatcagag gtgcattgag ttggtctgtt acagagagcg gtggtgttga gaaatccgca
    33361 cagatgtcaa ggctagtagc tgaggatcag aaatcagata tgaaaagtag cagacccatt
    33421 ttatggtctg aaacagtggt ggtaccgcgg aaatcgtaac acgaaattcg tccctgtcta
    33481 ggttatctag gcagggatta tttggtttca tttgaaagaa gatgatggct tattgttaaa
    33541 atgttgttag aagtatataa tagaaaaact ttgcccaaag tggaaacaga acggctgcta
    33601 ttacgtcaac gaaaagggga caaggcattg ttccagaagc ggcttcagct ctgattgaaa
    33661 ttggttttac cttacttgat ttgcataaaa ttgagctggg ttgctacgac tacaacaagc
    33721 aaagtcaggc agtggctcgc aaattaggct ttaccttaga agccaatgcc cgtgaccgta
    33781 aggacgttca aggtcgccgc tgtggcgaca tgcgttttgg gttactgaga agtgagtggg
    33841 aggagcagaa acaaaaatga accttatcat cattggtgct caagcgtcgg gcaagatgac
    33901 cattgggcaa gaagttgcca ggcagacagg catgactttg tttcataatc acgattctat
    33961 tgactttgtt ttacggttta tgccttggtc tcaagagagc actgccttga ttgaacgtat
    34021 ccgttttgct ttttttgaaa cctttgctaa gacaggtcaa gacatgattt ttactattgt
    34081 aattgacttc aatgatccaa atgatgtagc aatgcttgaa aagattcagg ctgtttttca
    34141 gtcttatgac caagaggttc tctttgtcga attaaaaaca gatatagagg aacgtcttaa
    34201 acgcaatcgc acagaaaatc gtctcaaaca taaacctctt aaacgcaaca tcgagtggtc
    34261 agaacaagat attcaatcca cgatggcata tgctgttttt aatccagaag aaccacccaa
    34321 aacgctcacg cattaccaaa aaatcaataa tacccagctc accgctgctg aaacagcgca
    34381 gcttattatc caaaaaatga ctcatatcaa ggagaactaa gatgacagaa ctatcaccta
    34441 aatacaatcc tgccgaggtt gaggcaggtc gctatcaaaa atggcttgat gcagatgttt
    34501 tcaagccatc aggagaccaa aaagcaaaac cgtattctat cgtgattcca ccgccaaatg
    34561 tgactggtaa gttgcacttg ggacatgctt gggacacaac acttcaagat attatcattc
    34621 gtcaaaaacg catgcagggc tttgatacgc tttggcttcc agggatggac catgcaggaa
    34681 ttgcgacaca ggctaaggta gaggagcgtc tgcgcgagca ggggatttct cgttacgacc
    34741 ttggtcgtga caaattccta gacaaggtct gggagtggaa agacgaatat gccactacga
    34801 ttaaagagca gtggggcaaa atggggcttt ctgtggacta cagccgtgag cgcttcaccc
    34861 ttgatgaggg cttgtcaaaa gcagttcgca aggtttttgt tgacctctac aaaaaaggct
    34921 ggatttaccg tggtgaattc atcatcaact gggatcctgc tgccagaact gccctttctg
    34981 acatcgaggt tatccacaag gatgttgagg gagctttcta tcacatgaac tatatgttgg
    35041 aagatggctc acgcgccctt caagtggcaa caacgcgacc agaaaccatg tttggagacg
    35101 ttgccgttgc cgtaaaccca gaagatcctc gttacaaaga tttgattggc aaaaatgtta
    35161 ttttaccaat cgtgaataaa ttgattccaa tcgtgggtga cgagcatgct gaccctgaat
    35221 ttgggactgg agttgtgaaa atcacgcctg cccatgatcc taacgatttc gaggttggtc
    35281 aacgccataa tctaccacaa gtgaatgtca tgaacgatga cggtaccatg aatgagttag
    35341 ctggcgactt tgcaggcatg gaccgttttg aagctcgtca agctaccgtt gctaaacttg
    35401 aagaacttgg cgccctagta aacatcgaaa aacgtgttca ctcagtaggt cactcagaac
    35461 gttcaggtgc agtcgttgag cctcgtctat ccactcaatg gtttgtaaaa atggatgagc
    35521 ttgctaaaca agctatggac aaccaagaaa cagatgaccg agtagatttc tacccaccac
    35581 gtttcaacga taccttcctc caatggatgg aaaatgtcca tgactgggta atctctcgcc
    35641 aattatggtg gggtcaccaa attcctgctt ggtacaatgc agaaggtgag atttacgttg
    35701 gcgaagaagc accagaaggt gatgactgga ctcaagatga agatgttctt gacacttggt
    35761 tctcatctgc tttatggccg ttctcaacta tggggtggcc tgacacagat gtagaagatt
    35821 tcaaacgtta tttcccaacc tcaaccttag taacaggtta tgacatcatt ttcttctggg
    35881 tgtcacgtat gattttccaa tcgcttgaat ttaccgggcg tcagccattc caaaatgtcc
    35941 tgattcacgg tcttattcgt gacgaagaag gacgcaaaat gtctaaatca ttggggaacg
    36001 ggattgatcc gatggatgtc attgagaaat atggtgccga tagcttacgt tggttcctct
    36061 caaacggctc tgccccagga caagacgtgc gtttctcata cgaaaaaatg gacgcctctt
    36121 ggaatttcat taataaaatt tggaatattt ctcgctatat cctcatgaat aatgaagggt
    36181 tgacattgga agatgctgaa agtaatgtgg ctaaggtagc tgcctcagaa gctggaaatg
    36241 tgactgacca gtggattctc cacaatctca atgaaaccat cgctaaagtg acagaaaact
    36301 ttgacaagtt tgagtttggt gtggcaggac acattcttta caactttatt tgggaagaat
    36361 ttgccaactg gtatgtggaa ttgaccaagg aagtgctgta tagcgacaac gaagctgaaa
    36421 aagttatcac gcgctctgtc cttctttata ctttggacaa gattttacgt ctccttcacc
    36481 caatcatgcc atttgtaaca gaagaaattt acgctcaata tgcccaaggt tctattgtga
    36541 cggtggacta tcctgtggtt cgcccagctt ttgaaaatga agctgcgcat aaaggtgtgg
    36601 aaagtttgaa agacctgatt cgtgcagttc gtaatgcgcg cgctgaagtt aacgtggcac
    36661 catcaaaacc aatcaccatt ttggtgaaga cagcagatag tgaattagaa gactttttca
    36721 acagcaatat caactacatc aaatgcttca ctaaccctga aaaattagaa atcagctcag
    36781 ccattgctgc gccagaactg gctatgacca gcatcatcac aggtgctgaa atctacttgc
    36841 cactagcaga tttgcttaac gtggaagaag aacttgctcg cctagataaa gaactggcta
    36901 aatggcaaaa agaactggac atggtcggca aaaaactcgg caacgaacgc tttgttgcca
    36961 acgccaaacc agaagttgtc caaaaagaaa aagacaaaca agctgactac caagctaagt
    37021 acgacgcaac ccaagaacgg attgcagaga tgaagaaaat taaatcatag tgtttagaac
    37081 gcagttgaaa aactgtgttc ttttcttact aatagagata ttagattgaa gtttaattat
    37141 gagaaaaacg ctttctttat ttaaagagtt atgttacaat actattacaa tcatcgtaca
    37201 aatagtgtta ttttgagagg catatgagaa tgattttagc acactatgac tgtaaaaaag
    37261 ataaaaagca atctttagat gagcatttat ggcatgtggc ctgttctagt cgacaggaag
    37321 catctataat tggtcaagga gatgtgcttt ttttaattgg tctttaccac gacctgggca
    37381 aagctgatcg aacctttcaa gataaattat taaataatcc aaatcggcat gttgatcact
    37441 cttatgcagg ggcaaaatac ttatgttcta ttattgggcc tcatctaaaa aaccgagggg
    37501 ttgataaaaa tgagagaatg acattcaacg aaatggtggg gtatgtcatc tctgctcatc
    37561 atgggatgta tgatttatgc tactattttg acgatgctga atattatggc tttaataagt
    37621 ttaaaaatcg tatcaataga gacttagatg gttatcacta tcatgaagat attaaagggt
    37681 acgctctaaa attagaaaaa aaattatgtg attatggcta caaagattta agggagctta
    37741 ttgataaagc ttttgataat taccaacaag ccatgtcttc cttaaactgg caagataaga
    37801 gtgagtggga ttattatcag tcttgtatgg tgagacttta cttgtcactc ttaaaaaacg
    37861 ctgatatttt ggacacagta aatgcctatg gccttaagat aagtcctatg gataaaacag
    37921 agcgatcctt tctaaaacac tcctatttag cggccattga acaaaaatat gctagctttg
    37981 gacagccaaa caatcagttg aacactattc ggacagaaat cgctgagcgt gttaaagaaa
    38041 gaggtaaacg agattccaag gggatttatc gcttagattt accgacagga gctggcaaga
    38101 ctaatcttag tatgcgttat gcgtttcacc aattagttca tcacgacaaa tcaaggtttt
    38161 tttacataac gccctttctt tcggttcttg agcaaaatgc ttccgaaatt agaaaagtta
    38221 caggtgacct tggcgttcta gaacaccatt ccaatgtggt gaaacaggct aatgaagatg
    38281 atgatgataa ggacagttta ttgtcagctt atcttagtga tagctgggac agtcaagtag
    38341 tcttgacttc tatggttcaa tttttccaaa cacttttcaa aacaaaatca gctaatctga
    38401 gacgtttttc aagtttgatt aatagtgttg tgattctaga tgaagttcaa tccctgccta
    38461 ttgaagtcac cactttgttt aatttaacga tgaatttttt aaataaagtt atggatacaa
    38521 ccatcgttct ttgcacagcg acacaacctg cttatgattc ttcagagatt gaccatcgta
    38581 tctgttatgg agggaacttg ggagaattag ctgaaatagt tgagttaacg attgaagaaa
    38641 aacagatttt ttcaaggaca gagcttagaa aatttgatga tagtgatcag aaagttcact
    38701 tgactgatgt tattaacctt attctaggtg aggaaaactc agttcttgct atttttaata
    38761 cgaaaaaaac ggttcataac tgctatacta tgctaaaaga catgactgat agaccggtct
    38821 atcagctttc gacaaatatg tgtgcgcagc atagacttga cttgattgct aagatcaaaa
    38881 cggagttaca aaataatatc cctattattt gtattagcac gcaattaatt gaagcaggtg
    38941 tagatgttga ttttcatcgc gtcattcgtt cctactcagg gattgattct attgttcagg
    39001 ctgctggacg gtgtaaccga gaaggcaaac gagataaagg gcaagtcact cttgtcaatc
    39061 tgaccaatga agaggaaaat atttctaggc tgacagaaat aaaaactaaa aaagaagcca
    39121 cagaatctat tcttcataag attgggtctc caattgatat ctcaacttta aaccgtgact
    39181 tttttgagta ttattatgcc aataatcagg gactgatgga ttatcctttg gaagacaacc
    39241 tatcaatcta cgactattta agccttaata tttatcagac ggcaaataaa aagttcaaag
    39301 gtaagttaaa acaagctttt aaaacagcag gagccaaaat gaacctcatc aataatgata
    39361 tgataggaat tctcgtacct tatggcgaag ctgagaaaaa attggcttat ttagaagaat
    39421 taggtgtgtc acatttttta tcagcaaaag attatcaaac gataaaatca ttactaaaag
    39481 agttacaacc ttttacggtt aatgtccgcg agaacgatcc tctctttgag acaacaaaat
    39541 cttatctaaa tggtcagatt ctggttttga cgtcggagta ttatgacacg gaaagaggag
    39601 ttaaatacga ttcagctagc ttttacttct aactcaaaac gaaagaagat taacaaaagg
    39661 ttgttagagg accttgttaa cctgccaatc atcattagta attattatca atttagacta
    39721 tttaataaaa ttagattaca aaaaaacaga aggaggaaag tagcttgtac agatctagag
    39781 acttctacgt gagagtaagt ggtcagcgag ctctttttac aaatccagcc acaaaagggg
    39841 gatcggaacg ctcatcctat tcggttccga ctagacaggc actgaatggt atcgttgatg
    39901 ccatctatta taagccgacc tttactaata tcgtcacaga ggttaaggtt attaaccaga
    39961 ttcaaaccga attacagggt gtcagggctc tgttacatga ttatagtgca gatttaagtt
    40021 atgtatccta tttgagtgat gttgtttatc tgatcaagtt tcattttgtt tggaatgaag
    40081 atagaaaaga tttgaactca gatagacttc cagctaaaca tgaagccatt atggagcgtt
    40141 ctattcgtaa agggggacgt cgagatgtgt ttttgggtac aagagaatgt ttagggcttg
    40201 tagatgatat cagccaagaa gagtatgaga ctactgtgtc gtattataat ggtgtcaata
    40261 tcgacttggg aatcatgttc cattcctttg cctatccgaa ggacaaaaag acaccattaa
    40321 aatcatactt tacaaagact gtgatgaaaa atggagtcat tacgtttaaa gcacagtctg
    40381 aatgcgatat tgttaacacg ctttctagtt atgcttttaa agcaccagag gagataaaat
    40441 cggttaacga tgaatgcatg gagtatgatg ccatggagaa aggagaaaac tgatggattt
    40501 ttttacttct ctcttgaaga cttatgaaaa agcagagcta gcagacttgg ttgatcatca
    40561 aaaaagaaat aatgagccgg ttttactgcc gatttatcat acgagtttaa agtcaaatgg
    40621 taaaaatatc atttcagtga aacttgacaa agatggccag tttcacaagg cagaatttat
    40681 ggcagataag caaatgatta tttttcctgt aacggctgat tctgttgcta ggtcaggtag
    40741 tcatcctgca ccgcatcccc tagtcgataa atttgcttat tatagtgctg aaatggggca
    40801 gattcagtat gattcttttc ataagcaact gaataactgg attgattatt gtgaggaggg
    40861 tgatgtcaag aaatttttaa cctttgttca gcagttcatt ttgaagccag aatttctaac
    40921 attgattctt gattctttaa ttggtcctga ttatcaacat aatcaattaa aagtcacatt
    40981 ttgtgatgcc actggaaaag aaaaattaat tgatttatca gcttgctttt tagaattttc
    41041 aattgatcag ttccagggct ttaaaaatga atcggtttcg acatttaaag ccttacacca
    41101 atcctatatt tcttttgttg aagccaatcg tgaaaatctc ggtatttgta atattagtgg
    41161 acgagaggaa cagcttaccg ataagcatag aggtttgatg gggaatgcta aaatcatctc
    41221 tgttagtaat aaaagagaag cttataaagg acgttttaga gaacgcgaag acgtttttag
    41281 tgttggctat gaaacttccg aaaagattca tttaatgctc aagtaccttt tagaaaataa
    41341 aaataccagt acttggttag ggtcttctca atatttaatc aactggttca gcgatgattt
    41401 aacaaatgat agtcggttgg atattgtatc accaatcttt gatgatggac ttgaagaaga
    41461 agatgatgac gatacgcctc ctgttataac attagcaact gaagacaata aaagaattgg
    41521 taaatcattc atcaagggac aaaaattatt tgctaatgat gccacttact acgttgctat
    41581 tttgaataaa accagcaatg ggcggattgc tttaaaatat tttcgtcagc ttcaagcgtc
    41641 ccaattactc accaatctta acaagtggca ggaaacatac agttgggagt cgcgatctaa
    41701 gtttgggaaa agtcgcttaa gaacccctac ttttcatgac atccttaatg tgtcctacgg
    41761 ggttgatagg gatcgcttcc ttgaattaga taatgataac ttcaaaagtg atcaaattca
    41821 aaagttagtg gcaagtttga ttgatggtaa accgatgcca cagtccattg tcaaaaagtt
    41881 aggtaacaat gttaaagaac gacatcgtta ccgtaagcac tggtatcaag ttgagcaggt
    41941 ctgcttagca attttacaca aacaaaatgg ggaggaattt tcaccgatgc tagatcatac
    42001 caatcaaaat cgttcctatc tttttggacg attattagca atttttgaat taatcgagac
    42061 cttgcgttat ggcttggatg gaaacaataa cgaccgtatt accaatgctg aacgttattg
    42121 gacagcctat actggacaac caacaaaatt gatgatgtta ttggaaaata aaattaagcc
    42181 ttacgaagaa ccattgaaat taaatcgtcg tggcagttgg atgaaattag aaaaagaaaa
    42241 agaagagatt ttagaactgt taaatcctct gttagaaaca gaaacaatgg aaaaaccctt
    42301 agattaccgc tttatttttg ggtattatgc tgagaaaaac tattactata caaaacaaaa
    42361 cacggaagta acagaaagtg aggagtaaaa agatgttgga acacaaaatt gattttatgg
    42421 taactcttga agtgaaagaa gcaaatgcaa atggtgatcc cttaaatgga aacatgcctc
    42481 gtacagatgc caaaggatat ggtgtgatga gtgatgtctc cattaaacgt aagattcgta
    42541 atcgtttgca agatatgggg aagtctattt ttgtgcaagc taatgagcgt attgaagatg
    42601 attttcgttc actggaaaaa cgcttttcgc aacattttac agctaagaca cctgacaaag
    42661 aaattgaaga aaaagcaaat gcattatggt ttgatgttcg tgcttttgga caagttttta
    42721 cttatctgaa aaaatcaatt ggggtgcgtg gaccagtttc catcagtatg gctaagtcct
    42781 tggagccaat tgtcatttcc agccttcaaa ttacgcgtag taccaatggt atggaagcta
    42841 agaataatag tggccgctct tctgatacga tggggacaaa acattttgta gattatggtg
    42901 tgtatgtact taaaggttct atcaatgctt attttgctga aaagactggt ttttctcagg
    42961 aagatgctga ggctattaaa gaagttttgg ttagcttgtt tgaaaatgat gcgtcgtctg
    43021 cacgtccgga aggctctatg cgagtttgtg aagtcttttg gtttacgcat tcaagcaaat
    43081 tgggaaatgt ttcaagtgcg cgtgtctttg acttgttaga gtatcatcaa tcaatagaag
    43141 aaaaaagcac ttatgacgct tatcagattc atctaaatca agaaaaattg gctaaatatg
    43201 aagcgaaagg gttaacgctt gaaatcctag aaggactcta gtatggtcta tgccgaagat
    43261 gattatttaa tgctgtcagg tattcagcat ttccaatttt gtaaacgtca atgggcgttg
    43321 atccatattg agcaacaatg gcttgataat gaagcgacag cgcatggaca ggttttacat
    43381 actaaagcag ataaccctta cattaaagaa aaacgaaaag agcttttggt ctcacgtgct
    43441 atgcccattt cttctgcaga acttggactt tcaggaatta tggatgttgt ggaattttat
    43501 aaagatgatc aaggtgtgtc tttgagggga aaacgtggga aatggttacc aaaagttgtg
    43561 gaatacaagc gcggaaaacc taaaaaagat accagagata ttgtccagtt ggtggctcag
    43621 accatgtgtt tagaagaaac gctagactgc gacattaacg aaggttgtct ttattaccat
    43681 agtgtcaatc aaagagtgat tgttcctatg acatcagctt tgcgtcaaga agtgaaggaa
    43741 ttagccgcag agatgcatga ggtttatcag agtcaaatgc tacctaaagc agcttatttt
    43801 aaaaactgtc agctttgttc tttagtcgat atttgtaagc ccaggttgag taaaaaaaca
    43861 aggagtgtgt cgcgttacat caatgaggct atgaccagtg aggagatgga cctatgaaga
    43921 agttgctaaa taccttgtat ttgacgcaag aagattttta tgtcactaaa gagggcgata
    43981 acattgttat caagcaagaa ggtaaggttc tcaaacggtt tccgtttcgg attattgacg
    44041 gtattgtctg tttttcttat ttgggtgtgt cgtctgtttt ggtgaagtta tgtacggaga
    44101 atcagattaa tttatcgttt catacaccac aagggcgttt ttgtggtcgc tatattggtt
    44161 caaccaatgg gaatgtgttg ttgcgtagag aacattatcg tttatctgat cgtgaggaat
    44221 ctttggaata cgcaaagcgg tttattttgg ctaaaatttc caactcaagg aaatacttgc
    44281 tacgctttaa acgagatcat cgtcaacaga ttgataccaa gctttttgag gctgttaatg
    44341 acgaattgat atgggcttta gagatggttc aggcagcaga taataaagac tctttaagag
    44401 ggattgaagg ccaagctgct aatcagtatt ttcgcatatt taatgacctg gtgttgacgg
    44461 acaaaaaaac gttttacttc caaggtcgga gtaaacgacc acccttagat tgtgttaatg
    44521 ccctcttgtc ttttggttac agtttactga cctttgaatg tcaatctgcc ttggaagctg
    44581 tcggattaga cagttacgtt ggtttctttc acacggatcg tcctgggcgt gctagtttag
    44641 cgcttgattt agttgaagag ttccgctcat atattgtaga tcgttttgtc ttttcattaa
    44701 ttaataaagg acaacttcag aaaaaacact ttgaggttaa agaaaatggt agtattttat
    44761 tgacggaaaa tggcagagct atttttattg atttgtggca gaagcgtaag catactgagg
    44821 tagaacatcc ttttacaaaa gagaaagtaa aacttatgtt attaccctat gtacaagcgc
    44881 agcttttagc taaggctata cgaggagatt tagaaagcta tccacctttt atggtttagg
    44941 agatgttata tgatggtttt agtcacttat gatgtaaata cggaaacacc tgctggtaga
    45001 aaaagattgc gtcatgttgc caaactctgt gtggactatg ggcaacgtgt tcaaaattct
    45061 gtttttgaat gttctgtgac acccgcagaa tttgtggata taaagcaccg cttaacacaa
    45121 atcattgatg agaaaactga tagtattcgc ttttatttat tggggaaaaa ttggcagagg
    45181 cgtgtggaaa cacttggtcg ctcagacagc tatgacccag ataaaggtgt cttattattg
    45241 taaaaatctc ttgtgcgaag ctagctttca cagaaacacc ttgcttgctc gcgcaaaaat
    45301 aacttaaaaa agaagcgaaa tggagataaa aaggcttaaa acacctctat gtgtgccatc
    45361 cgtttctcta taaactgtgt catttggcgc agtctcaccc ttcatgggtg agtggatcga
    45421 aataaaaagc atatcacgaa aatcaccaat tacatcaggt ctcacccttc atgggtgagt
    45481 ggattgaaat aagtcatttt ctgcttctgc taggtttgct ttagtctcac ccttcatggg
    45541 tgagtggatt gaaatttttt actttgatta catcccgcaa tgtcacagcg tctcaccctt
    45601 catgggtgag tggattgaaa ttgtccgcat accttgattt gagcgagtaa actcgtctca
    45661 cccttcatgg gtgagtggat tgaaagatga acccgatctc tcttttaatg aggtcgggtt
    45721 tttacatgcc tttagtcaac catttatctg atagcgtatc aaattcaagt ttttgcatgt
    45781 tctagtctat ggtttgcgcc actagctttc ggtaaactaa gggtaactta agagaggagt
    45841 tatttatgac actatcactt gtattaatgg tatcggtttt tggggcaggc ttgttatcct
    45901 ttttctctcc gtgtatcttt ccggtccttc ctgtctattt aggcatttta ctggatgcag
    45961 atgattcaaa gacgattact atatttggta aaaaactcta ttggtatggc attgtcaaaa
    46021 ctttagcctt tatttttggt ctatctacta tttttgtgat tttaggttac ggggctggtt
    46081 ttttaggaaa tatcctttat gcggtatggt ttcggtactt actgggagcc ttggtcatta
    46141 tcttggggat tcatcagatg ggcctcatta ccattaagag cttacaattt caaaaatcac
    46201 tgactttcca taataacaag aatcgcaacg gtttgttcaa tgcatttatc cttggtttaa
    46261 cctttagctt tggttggacg ccttgtgtgg gacctgtttt gagttctgtc ctagcattgg
    46321 tggcttcagg gggaaatggt gcctggcaag gtggcgtttt gatgattatt tatactcttg
    46381 gattgggcat tcctttccta ctcatctctt ttgcgtcagg cattgttttg aaacagttta
    46441 acaagctcaa accccacata cttttactga aaaaagtagg aggcgttctg attatagtca
    46501 tgggaatctt gcttatgaca ggaaccttaa ataacttagc acaacttttt ggataaagga
    46561 gaaacacaat gaaaaaagga ctattagtaa caactggttt ggcttgtctc gggctactaa
    46621 ctgcttgctc aacccaagac aatatggcta aaaaggaaat aactcaggac aagatgagca
    46681 tggcagctaa aaagaaagat aagatgtcaa catcaaagga caagtccatg atggcagata
    46741 aatcatctga taagaaaatg accaatgatg gtcctatggc gcctgatttc gaactcaaag
    46801 gcatcgatgg taagacctat cgcttatcag agttcaaagg taaaaaagtt tatttgaaat
    46861 tttgggcctc ttggtgttca atctgtctat caaccttggc agataccgaa gacctggcta
    46921 aaatgtcaga taaagactat gtggtcctaa cagttgtctc gccaggtcat caaggggaaa
    46981 aatcagaagc agactttaaa aaatggttcc aaggaacaga ctataaggac ttaccagtct
    47041 tgttagatcc ggatggcaag ctattggaag cttacggtgt cagatcttac ccaacagaag
    47101 ttttcattgg aagtgatggt gttcttgcta aaaaacacat tggttatgcc aaaaaatcag
    47161 acatcaaaaa gacccttaaa ggtatacatt aggaaggacc agctgatagg cattagaaaa
    47221 aaggagttga gtttatggaa cataaatgga aattatggct atttatcgtt ggagtggtct
    47281 tgttaatagg cggagcttct gttctcattc agaaaggtca agccaaggct tttagtcaag
    47341 gcaagcctca actaccagct aaaaaagtca aatccactaa agtagatccc aatgcccctg
    47401 ttgatcaaaa agtgatttac ctggctggag gctgtttctg gggcgttgaa gaatattttt
    47461 cacaagtgga tggcgttcta gatgcggtgt caggctatgc caatggtaga ggcgatacca
    47521 ccaactacca gttaattcat cagactggtc atgcagaaac cgttgaagtg gcctatgatg
    47581 cgaaccgtat tagcttgaaa gaattattac tgcatttttt ccgaattatt gacccaacca
    47641 gtcttaataa gcaaggaaat gatcgcggta gtcaataccg aactgggatt tactatactg
    47701 acaaagcaga tttagctatt attgatgagg tcttcaaaga aaaagctaag gattacaaga
    47761 aaaaaatagt ggttgaaaaa gcaccattga aacactttat taaggcagaa gactaccacc
    47821 aagattacct caagaaaaat ccaaatggct actgccatat tgacatcaac caagcgactt
    47881 atcctgtgat tgatgaaagc aagtacccaa aaccaagtgc cactgagatc aaggaaaaac
    47941 tatctgcaga cgaataccga gtgacgcaaa aaaacgaaac tgaaaaagct ttttctaatc
    48001 gctactggga ttcttttgat gcaggaattt acgtagacgt tgtgacagga gaaccgcttt
    48061 tctcttcaaa agacaaattt gaatcaggtt gtggttggcc aagctttagc cgccccatca
    48121 gcccagacgt tgtccgctac aaggaagata agagtttcaa tatgacgaga acagaagtgc
    48181 gcagccgttc agggaattct catctggggc atgtctttac tgacggacct aaagaccaag
    48241 gcggccttcg ttactgcatc aatagcttgt ctattacctt tattccaaaa tctgatatgg
    48301 aagctaaggg ctatggttat ttattatcat ctgtagaata gggttaggcc taaaaatctg
    48361 atataataga agaaagacta gtatgagagg gccatgcaag gccctttata aagataagga
    48421 gacaccgtgt gtactcattg ttaattgtag aagacgaata ccttgtgcgc cagggtattc
    48481 gttctttggt tgattttagc cagttcaaga ttgatcgggt caacgaagca gaaaatggcc
    48541 agttggcttg ggacttgttt cagaaagagc cttatgatat tgttttgacg gatatcaata
    48601 tgcccaaatt aaatgggatt caactagcag aactcattaa acaggaatcc ccccaaactc
    48661 atctggtatt tttgacgggc tacgatgatt ttaactatgc cttatctgct ttgaaattag
    48721 gggcagatga ttacttgctc aaaccctttt ccaaggcaga tgtagaagac atgttaggaa
    48781 agctccggaa aaaattagaa ctttccaaga aaacagaaac cattcaggaa ttggttgagc
    48841 agcctcaaaa agaagtatca gcaatagcaa tggctattca tgagcggttg gcagattctg
    48901 atttgaccct aaaaagcttg gctcagcagc ttggttttag ccctaattac cttagcgtct
    48961 tgattaaaaa agagttaggg atgccctttc aagattatct ggtacaagaa cggttgaaaa
    49021 aagccaagct tctcttgtta accagtaatc ttaaaatcta tgaaattgca gagcaggtcg
    49081 gttttgagga catgaattat ttttctcagc gctttaagca actggtaggc gttaccccaa
    49141 gtcagtataa aaaaggaggc caggcatgaa gcgttatccc ctactggtcc agttgatttc
    49201 gtatgttttt gtgatcgtaa ttgccctcat taccacgctt ggtttgcttt attaccagac
    49261 gagttctcgt aatatcaggc aactaattga acgtgatacc cggcagagca ttcggcaaag
    49321 ttcccaattt attgacgctt acatcaagcc tcttaaagaa acaacttcgg tgctggcgaa
    49381 aaatacggaa attcaagcct ttgctagtca aattcatcaa gaaaatgaca aacaggttct
    49441 tcagctcatg aagatggttc ttgcgaccaa ttccgattta caagcagctg ttctggtgac
    49501 taaggatggt cgaacggtgt ctaccaattc tcagttgacc atgaaaacct ccagtgacat
    49561 gatggcagaa ccctggtata aagcagccat agaccgtcaa gccatgccaa tcttaacccc
    49621 agctcggcaa ttatcccttt cttctaaaaa agaatgggta gtttctgtga cccaagaggt
    49681 agtagatagg gctgggcata atttaggtgt gctaagactt gatattgcat acccgaccat
    49741 taaagcgtct ttagatcagc ttcagctagg ccgccaaggc tttgccttta ttgtgaatga
    49801 taagcatgaa tttgtttacc atcccaaaaa gagtgtttac agttcttcta aggagatggc
    49861 tgcgatgaaa ccttatttag cgattcagaa tggttacact aaggacaaga catcttttgt
    49921 ttaccaaaaa ctcattccta acagtcaatg gactttagtg ggagtggcgt cactggatca
    49981 gttgcaccgg gtgcagcgcc aaattttttg gtcctttctt ggaacagggc ttctagcctg
    50041 tctgatttgt ggctttgcaa ctgtcttagt cttacgcaga tggattcgtc ccattcaaca
    50101 attgcagcaa gttattcttg ctattcaaaa aggagatcgt cagttacgtg cccaagaaac
    50161 gggttctcca gaattgacag accttgccca acagtttaat gcgctcttag atcaaattga
    50221 tagcttgatg gttgccgttg cggataagga aaaggcgatt gggcagtata ggttacaagc
    50281 cttggctagt cagattaacc cgcattttct ctataacacc ttggacacta ttatttggat
    50341 ggcagaattt aatgacagca agcgcgtggt agaagtgacc aagtctctag ctaagtattt
    50401 tcgtttggcc cttaatcagg ggaacgaata cattcgtttg gcagatgaac tggatcacgt
    50461 tagccaatac ctctttattc aaaaacagcg ctatggagac aagctaagtt atgaagtgca
    50521 aggcttagat gtctacgcag actttgttat tcctaagctt atcttacagc ccttagtaga
    50581 aaatgctatc taccatggca tcaaagaagt cgatcgcaag ggcatgatca aggttacggt
    50641 atctgataca gctcagcatc tgatgttgac tgtttgggat aatggtaaag gcattgaaga
    50701 ctcttcactg accaatagtc agagcttgtt ggctagggga ggtgtgggcc ttaaaaatgt
    50761 tgaccagcgg ttaaaacttc actatggtga aggctaccac atgaccattc atagccagtc
    50821 agaccagttc actgaaatac aattaagcct tcctaaaatg catgaattaa tggcagacga
    50881 cacacaggaa aacgagtaag gttacaggaa gtgcatgtca gccatttccc taagttaggg
    50941 tattggagat aggaacctta gaaaggatat catgagttta gcaactgact attttagccg
    51001 acagaccccc atagttgaaa agctaatggc ttacggtttt gagaagcgag acaacggtta
    51061 tttctataac gaacggttta tggaagggga atttgaggcg cagcttagga ttgatgaggc
    51121 tggcaatatc tgggatcggg ttattgattg tgacttggag gaggattatt tgcctttaca
    51181 acaagcagcc tggcaaggaa cctatactgg gcaggttaga gcggcctatt tggaactttt
    51241 ggagcgctta tcagtagcct gttttgaagc cactcctttt cagtcaatgc aagctaatag
    51301 acttgctaag catatcacca aagaatggtc tgacccaatg gactatcctt ttgaaaagca
    51361 cccagacctt gcaacctatc gggtaggggg caaatggtat gctatgattt tttctctctt
    51421 ggctgataaa ttagaccaga taccagagag attagtagga cagacatgtg aagtgatgac
    51481 tgtcaaagtt aatcccaagg ctttccctca gttactgcag caagaaggca tttacccagc
    51541 gtatcacatg tcaaagaaaa actggattag tattattttg gatgataagg taacagatga
    51601 taagctttgg acgttagtga ctcaaagtcg tcaactagtc aacccaaacg gtctttctaa
    51661 tcctaatggt cctgattatt gggttattcc agctaatttg aaatactatg acattgatgc
    51721 agaatttgca gccaatgatg tgattttatg gacccaaaaa gctggtattg ccgtgggaga
    51781 ctacgtgctg atttatataa cagccccagt caaatccatt cgctatgtct gccaagttct
    51841 agaaactgat atacctaacg agggttatcg taaaaatcct aacattgaca aactcatgcg
    51901 tctccgaaaa tgccaacagt acaaggatgg tctcttgtct tttgacctta tgaaaaaaca
    51961 tggcgtagct gcagtgagag ggccaagacg attaagccct caattaattg catttttaaa
    52021 ggaaaaagag tattttaaag agaacaacta aaggagaata agagatggtt gaatttgtag
    52081 cagatcaaag tttttgggaa ctttttccag gtgccaaact aggtgtcgtc ttattaaagg
    52141 atgttcagaa ccaagcagag tcaccagaag atgtcaaaca gctcttagca gacagccatg
    52201 agttagcaaa agcttattta acagcagaca attttagtga taatcaggtg gttcaagtct
    52261 accgcaaggc ctatcaacac tttaaaacca aaaaaggagc tcgctctagc attgaagccc
    52321 ttctcaagcg ggtgtcaaat ggtcaaagca ttccgtctat taacccacta gtggatattt
    52381 ataatgcggc tagtctacgt tttggtttac ctgctggagc cgaagatagt gacagtttta
    52441 tcggagattt gcgtctgacg ataacagatg gtggtgacga cttttacttg attggggatg
    52501 ctgacaacaa cccaaccttg ccaaatgaac tctgttataa agatgatatt ggagcggttt
    52561 gtcgttgcct taactggcga gatggcgaac gcaccatggt gacagaacac accaaaaatg
    52621 catttctgat tatcgaagct cttgatcaag aaggtcaaaa tagattgcaa gaagctctga
    52681 aattcattga aggcagcgca aaaatgtacc ttcatgcaat cacttctgtg catgtgttgg
    52741 ataaagacaa tccacacgtg ccacttttta cagaaaacta gattagtagg atgagctgtg
    52801 taaaaataga aggttaacaa aaagcgagta aacgaatgtc ctgtcattta ggttttcgtt
    52861 tactcgcttt ttgatgagat tttactgctg tcctagcaaa aggtgaggat gaggtcgtat
    52921 atcacataga ggttttctgt taagccttat ttgttactaa agaagaatgg tggcgtgtaa
    52981 tgactaaggg tttcgtaaca ggccttagct tgctcattgt cttcacagac aatcaagcaa
    53041 gtatcatcac cacagaccgt tgctacaatt tctggaattt gcatggcatc taaaatggag
    53101 ccaaaggatt gggctagtcc aggtaacgtt tttaaaataa tttgatgttg aactatcttt
    53161 aacatgacca aagcgtcttc catgtaaaaa cgaagacgat gttcccagcg ggtttgtgaa
    53221 atggctaacg cttcatagtg tgtgtcgttt ccagaagtta ctttgaccag gttcaattcc
    53281 ttcatgtcac gtgatagggt agcctgagtg atcgtgatgc catttttttg caaccgttct
    53341 tgtaattctt gctgtgtatg tatagttgtc tcagagatga gggaacgtat gagttggtga
    53401 cgcgtctctt tcttattcat tgttataatc ttcctttaac gtaattgata acaatccgag
    53461 tatagcaaaa agaggagaag gtgtaaagtt tttgatgaac cgcttacaaa atggcttttt
    53521 tatggtaaaa taaagatgat gtttagaaaa aggagatttg tgtgattcga agagaagatt
    53581 atcaatacct tagaaaacta aacgattttc gctacttttc tattgaacaa tttgacaaaa
    53641 ttgtagggca gatggaattc cgaaaagcta aaaaggacca tatccttttt tttgagggag
    53701 ataaaagaga taagcttttt ctagtgacct ctggttattt caaggtggag cagtccgatc
    53761 aatcaggaac cttcatgtat acggatttca tcagacacgg caccattttt ccttacggtg
    53821 gcctctttac agatgattat taccattttt cagtggtagc catgacagac gtgacttatt
    53881 tttactttcc agtcgattta tttgaagatt attcgcttga aaatcgtcta caaatgaaac
    53941 acttatatag taagatgtct aagctgctcg agttacatga gttgagggtc cgaaacttga
    54001 ttacatcaag tgctagttct cgtgtgattc aatctctggc gattttgctg gttgaaatgg
    54061 gtaaagacag tgatacctta ccttttcaat taacaacaac agatattgct caaataagtg
    54121 ggacgacaag agaaacagtt agccatgtgc ttagagattt gaagaagcaa gaattgatta
    54181 ccataaaagg taagtatttg acttatctag ataaagacta ttttttacaa tacacaa
//
LOCUS       DAUGJR010000008        51922 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUGJR010000008 DAUGJR010000000
VERSION     DAUGJR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51922
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.008"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..197)
                     /locus_tag="VH800_000457"
     CDS             complement(<1..197)
                     /locus_tag="VH800_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361548.1"
                     /translation="MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIIT
                     EKIGDSGQALVIANGSLIFLIV"
     gene            complement(199..936)
                     /locus_tag="VH800_000458"
     CDS             complement(199..936)
                     /locus_tag="VH800_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361549.1"
                     /translation="MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGNIYCADKEISTFSDKEATNFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVILLKDGK
                     LHMEIDKKDCGESFYDVISQALSDRGE"
     gene            complement(933..1466)
                     /locus_tag="VH800_000459"
     CDS             complement(933..1466)
                     /locus_tag="VH800_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361550.1"
                     /translation="MDKTDFRNISAFVPQDSPIFDGDVMYNILLGRESVTEKQVIEIC
                     KRVSLYEDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRVLVTHRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDY
                     CDLYDSYMNKYQEEEVK"
     gene            complement(1468..3093)
                     /locus_tag="VH800_000460"
     CDS             complement(1468..3093)
                     /locus_tag="VH800_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEQ8361551.1"
                     /translation="MIKRNELKLEYQQHQFYEYFNSIFDYDILDTSIRETSEVLRKKT
                     HKLFYSEFENQLFETIMFLSMKTLVLDINHFSKEIENKSEAYEQYIQQIREENGINHF
                     FDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIKSCFNISEPLSNVAFSLGDSHS
                     KKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNIPSFSLPKSLVKADYCWQL
                     GVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDLHMENVIVSGGDLYLIDVETFFQRK
                     LNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNSAPNVSGISGKGGKRKKGKYEL
                     INKNRGDMKLVKVDYFQEDGFNIPTLNGKVVEPLDYANEIISGFRECYIFLLSQRSKI
                     KEIVEGFPELKSRVPFRNTSDYGKFLQASTNPKYLFSEKKRKNLFSILYETKHIEHFI
                     VDNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNLGDTTSLFDSITILNDERLKFTCE
                     LLEIVLKKPIKNWEREKGKSYQFLSISSEHYLL"
     gene            complement(3176..3331)
                     /locus_tag="VH800_000461"
     CDS             complement(3176..3331)
                     /locus_tag="VH800_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEQ8361552.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(3834..5240)
                     /gene="lacG"
                     /locus_tag="VH800_000462"
     CDS             complement(3834..5240)
                     /gene="lacG"
                     /locus_tag="VH800_000462"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEQ8361553.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDG
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(5328..7025)
                     /locus_tag="VH800_000463"
     CDS             complement(5328..7025)
                     /locus_tag="VH800_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8361554.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKACVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHTTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKAQFEN"
     gene            complement(7025..7342)
                     /locus_tag="VH800_000464"
     CDS             complement(7025..7342)
                     /locus_tag="VH800_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8361555.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(7366..8349)
                     /gene="lacD"
                     /locus_tag="VH800_000465"
     CDS             complement(7366..8349)
                     /gene="lacD"
                     /locus_tag="VH800_000465"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8361556.1"
                     /translation="MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEG
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(8353..9282)
                     /locus_tag="VH800_000466"
     CDS             complement(8353..9282)
                     /locus_tag="VH800_000466"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEQ8361557.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNEFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            complement(9330..9845)
                     /gene="lacB"
                     /locus_tag="VH800_000467"
     CDS             complement(9330..9845)
                     /gene="lacB"
                     /locus_tag="VH800_000467"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8361558.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(9880..10308)
                     /gene="lacA"
                     /locus_tag="VH800_000468"
     CDS             complement(9880..10308)
                     /gene="lacA"
                     /locus_tag="VH800_000468"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8361559.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTT
                     LAVVKEVNASDDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            10755..11528
                     /locus_tag="VH800_000469"
     CDS             10755..11528
                     /locus_tag="VH800_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8361560.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
     gene            12189..12476
                     /locus_tag="VH800_000470"
     CDS             12189..12476
                     /locus_tag="VH800_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HEQ8361561.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            12466..12801
                     /locus_tag="VH800_000471"
     CDS             12466..12801
                     /locus_tag="VH800_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8361562.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKIIHYHSTKGYTLSKDYIVLYHIEGEENRIVIDYLLPT
                     QSDYIKLFK"
     gene            12953..13423
                     /locus_tag="VH800_000472"
                     /pseudo
     CDS             12953..13423
                     /locus_tag="VH800_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988074.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            13469..13906
                     /locus_tag="VH800_000473"
     CDS             13469..13906
                     /locus_tag="VH800_000473"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8361563.1"
                     /translation="MEKSTKNDFSVRKIKLDSETISILQEWKAISQKEKTQLAVAPLS
                     IKSDFIFTYCTREGSIEPLHADYINNILSKVIKQHSLKKISPHSFRHTHATLMIEIGV
                     DPVNTAKRLGHASSQMTLDTYSHATAVGEDKSIKQFANCLKNN"
     gene            complement(14026..14418)
                     /gene="rpsI"
                     /locus_tag="VH800_000474"
     CDS             complement(14026..14418)
                     /gene="rpsI"
                     /locus_tag="VH800_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEQ8361564.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(14439..14885)
                     /gene="rplM"
                     /locus_tag="VH800_000475"
     CDS             complement(14439..14885)
                     /gene="rplM"
                     /locus_tag="VH800_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEQ8361565.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(15103..15309)
                     /locus_tag="VH800_000476"
     CDS             complement(15103..15309)
                     /locus_tag="VH800_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361566.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(15306..15812)
                     /locus_tag="VH800_000477"
     CDS             complement(15306..15812)
                     /locus_tag="VH800_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361567.1"
                     /translation="MFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGG
                     VAFVLTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLSMGASIFYRHY
                     LDAKEADE"
     gene            complement(15948..16808)
                     /locus_tag="VH800_000478"
     CDS             complement(15948..16808)
                     /locus_tag="VH800_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8361568.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(16905..17423)
                     /locus_tag="VH800_000479"
     CDS             complement(16905..17423)
                     /locus_tag="VH800_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEQ8361569.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            complement(17427..18173)
                     /gene="rlmB"
                     /locus_tag="VH800_000480"
     CDS             complement(17427..18173)
                     /gene="rlmB"
                     /locus_tag="VH800_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEQ8361570.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(18220..19017)
                     /locus_tag="VH800_000481"
     CDS             complement(18220..19017)
                     /locus_tag="VH800_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361571.1"
                     /translation="MTTMQKTISLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAM
                     TNSVDVDTKAQTNQSANQEIDSTSNPFRSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLLGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(19213..19626)
                     /locus_tag="VH800_000482"
     CDS             complement(19213..19626)
                     /locus_tag="VH800_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEQ8361572.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(19619..20962)
                     /locus_tag="VH800_000483"
     CDS             complement(19619..20962)
                     /locus_tag="VH800_000483"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEQ8361573.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNIYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKTIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAVQGIKLLDTKDGVRWLRD"
     gene            complement(20990..21220)
                     /locus_tag="VH800_000484"
     CDS             complement(20990..21220)
                     /locus_tag="VH800_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361574.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(21699..22280)
                     /gene="cysE"
                     /locus_tag="VH800_000485"
     CDS             complement(21699..22280)
                     /gene="cysE"
                     /locus_tag="VH800_000485"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEQ8361575.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTVRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(22289..23041)
                     /locus_tag="VH800_000486"
     CDS             complement(22289..23041)
                     /locus_tag="VH800_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEQ8361576.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLIFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(23034..25166)
                     /gene="pnp"
                     /locus_tag="VH800_000487"
     CDS             complement(23034..25166)
                     /gene="pnp"
                     /locus_tag="VH800_000487"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEQ8361577.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGDSTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDVDLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAIDRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            complement(25447..26178)
                     /locus_tag="VH800_000488"
     CDS             complement(25447..26178)
                     /locus_tag="VH800_000488"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEQ8361578.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTARVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDYNH"
     gene            complement(26188..27566)
                     /locus_tag="VH800_000489"
                     /pseudo
     CDS             complement(26188..27566)
                     /locus_tag="VH800_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            complement(27593..27877)
                     /locus_tag="VH800_000490"
     CDS             complement(27593..27877)
                     /locus_tag="VH800_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8361579.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            complement(27870..29930)
                     /locus_tag="VH800_000491"
     CDS             complement(27870..29930)
                     /locus_tag="VH800_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8361580.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKASKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQKKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKSVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(30282..30551)
                     /gene="rpsO"
                     /locus_tag="VH800_000492"
     CDS             complement(30282..30551)
                     /gene="rpsO"
                     /locus_tag="VH800_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEQ8361581.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     QHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(30709..30864)
                     /locus_tag="VH800_000493"
     CDS             complement(30709..30864)
                     /locus_tag="VH800_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361582.1"
                     /translation="MTMLGYRLSAEVRGSAILPLLAGYLIRQAIAQVYSDLKTASWLF
                     GLASSVA"
     gene            30990..31259
                     /locus_tag="VH800_000494"
     CDS             30990..31259
                     /locus_tag="VH800_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8361583.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTYRIADLDALTQLRPLRYAAH"
     gene            31360..31974
                     /locus_tag="VH800_000495"
     CDS             31360..31974
                     /locus_tag="VH800_000495"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8361584.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(32008..32550)
                     /locus_tag="VH800_000496"
     CDS             complement(32008..32550)
                     /locus_tag="VH800_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8361585.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(32681..33109)
                     /locus_tag="VH800_000497"
     CDS             complement(32681..33109)
                     /locus_tag="VH800_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8361586.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(33219..37616)
                     /locus_tag="VH800_000498"
     CDS             complement(33219..37616)
                     /locus_tag="VH800_000498"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEQ8361587.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYEPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            complement(37871..39727)
                     /locus_tag="VH800_000499"
     CDS             complement(37871..39727)
                     /locus_tag="VH800_000499"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEQ8361588.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSIASMDDIPKEVLEDIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHMTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            complement(39925..41184)
                     /gene="rseP"
                     /locus_tag="VH800_000500"
     CDS             complement(39925..41184)
                     /gene="rseP"
                     /locus_tag="VH800_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEQ8361589.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPTSLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSRAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(41257..42051)
                     /locus_tag="VH800_000501"
     CDS             complement(41257..42051)
                     /locus_tag="VH800_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEQ8361590.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(42064..42813)
                     /locus_tag="VH800_000502"
     CDS             complement(42064..42813)
                     /locus_tag="VH800_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEQ8361591.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            complement(43032..43397)
                     /gene="yajC"
                     /locus_tag="VH800_000503"
     CDS             complement(43032..43397)
                     /gene="yajC"
                     /locus_tag="VH800_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEQ8361592.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELLAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(43513..43887)
                     /locus_tag="VH800_000504"
     CDS             complement(43513..43887)
                     /locus_tag="VH800_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEQ8361593.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            complement(44002..47499)
                     /locus_tag="VH800_000505"
     CDS             complement(44002..47499)
                     /locus_tag="VH800_000505"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEQ8361594.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGLQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGHYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDRDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPGNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKAS
                     DDKVPNKATLIDAVAQYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLVDAEQAGVTAIAKPKGVQFTKEGLTIEGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGIALLLLAISLLMKRQKD"
     gene            complement(47697..49310)
                     /locus_tag="VH800_000506"
     CDS             complement(47697..49310)
                     /locus_tag="VH800_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEQ8361595.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDYYIWRDEPNNLMSIFSGSAWELDEASGQYYLHLFSK
                     KQPDLNWENAQLRQKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFATDLAGAQ
                     VIIANTDVDTVLETKHLQPWDAFCLKLKA"
     gene            complement(49439..50572)
                     /gene="ugpC"
                     /locus_tag="VH800_000507"
     CDS             complement(49439..50572)
                     /gene="ugpC"
                     /locus_tag="VH800_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEQ8361596.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLDIAIPEG
                     QAKMLEAAGYKGEKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(50870..51718)
                     /locus_tag="VH800_000508"
     CDS             complement(50870..51718)
                     /locus_tag="VH800_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEQ8361597.1"
                     /translation="MELKDYFPEMQVGPHPLGDKDWMSIKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLYETSQFIYLNHQQALPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
BASE COUNT        15577 a        11159 c         9332 g        15854 t
ORIGIN      
        1 acaatcaaaa aaatcaatga cccattagcg ataactagag cttgaccact atccccaatt
       61 ttttctgtaa tgattttatc tgagataaaa tttagaaaag ctataaaaat acttaataaa
      121 ccaatcgtag ctagaaaata gatacgatat aacgaaaaat tttttttaat gttagatttt
      181 gtaattgacc aaatcatatt actctcctct atcggataaa gcttgactaa ttacatcgta
      241 aaacgactct ccacaatctt ttttatcaat ctccatgtga agtttcccat ctttgaggag
      301 tataactctg tcagcataag aagctgataa aacgtcatga gtaaccatta aaatagttac
      361 cttttctgtt ttattgattt cactcaaaat catcattgtt tcctcagaag atttcaagtc
      421 aagtgctcca gttggttcgt cagcaaaaat aatctctggt tctttaatga ttgctctgat
      481 aatactgacc ctctgtcttt gacctccaga aagttgatac ggatatttct tcaactgttc
      541 atataaatta aatctttttg catagctatt tatcaaatca tcaatctttg aagaatcaat
      601 attttttaga gacaaagcaa cagaaatatt ctccctaatg gttagactat ctaacagcat
      661 ataatcttga aaaacaaaac caatatcatt ttttctaaaa ttagttgcct ccttatcaga
      721 gaatgtgcta atctctttat ccgcacaata aatattccca ctatcaattt tatcaataat
      781 tgaagtaaca tttaaaagcg tcgttttccc actaccgcta cgccccatga cagctacaaa
      841 ttctcctttt tccacaatca aattgatatg gtctagagca taattcagtt gattgggata
      901 ttttttgcaa acatctttta atactaattg tttcatttta cctcttcctc ctgatattta
      961 ttcatatacg agtcatataa gtcacaataa tccttattat ttttgtacaa ataatgatgg
     1021 tttccatagt caataatttt gccattatcc attattaaaa tcttatcagc tttttcaact
     1081 gtattaagtc tatgggtaac caaaaccctc gtacaatgta aagcctcaac atttttttgg
     1141 attattcttt cagtttttac atctaaagct gatgtaggtt catcaagaac taagattcta
     1201 ggggtagtta ctaactctct tgctagagaa attcgttgtt tttgcccccc agatagtgat
     1261 ggattgtctc gaaaaagtgg ggtatgaaac ttcattggca tactcctgat atcctcatat
     1321 agtgataccc ttttacagat ttcaataact tgtttttctg taacagattc tcttcctagc
     1381 aaaatgttat acatcacatc cccatcaaat attggagaat cttgaggtac aaaagccgat
     1441 atattcctaa aatcagtttt atcaatttta gagaaggtaa tgttctgagg agattgataa
     1501 aaactgataa gatttgccct tttccctctc ccaattctta atcggttttt tcaagactat
     1561 ttcaagcaat tcacaagtga acttcaatct ttcatcgttc aaaatagtta tactatcaaa
     1621 taacgaggtt gtatctccta gatttccaat taatgtccct acagaattat agacgtttcc
     1681 tctggtatcc attgaaaagt aaggaatatc accattcatc aaatctttaa tttcattatc
     1741 aacaataaaa tgttcaatat gttttgtctc atatagtatc gaaaataaat tcttcctctt
     1801 tttttctgag aaaagatatt ttggattcgt agaagcttgc aaaaattttc catagtcgga
     1861 agtatttcga aatgggactc tgcttttcaa ttctggaaaa ccttctacta tttctttaat
     1921 ctttgaacgt tgtgatagaa gaaatatgta gcactctcta aatcctgaaa tgatctcatt
     1981 agcatagtca agaggctcta ccactttccc atttaatgtg ggaatattga acccatcttc
     2041 ttgaaaatag tcaactttta ctaacttcat atctccacga tttttattta tcagttcata
     2101 ttttcctttt tttctttttc caccttttcc acttattcca gaaacgttag gagcgctgtt
     2161 tttctcaaat tgtacaggaa ataaaccgtt tgaaagtgat gtctcataaa ttctctgata
     2221 ggtgtctaca gtaatccctt caaaattctg attttgtaca ttcaactttc tttgaaaaaa
     2281 tgtttcaacg tcaattaaat ataaatctcc gcctgaaaca atcacatttt ccatatgtaa
     2341 gtccgtaata gaaaatattt cagaaaatgc tgctaaaaca ccatacttaa agtaaatttt
     2401 cgctacttca tctttattgg aacttgtata agctacacca agttgccaac aataatctgc
     2461 tttaactaag cttttaggaa gactgaatga gggtatatta ctagatttca ataaactagt
     2521 aagttctaac aagatactgt gtgaatgata acttttaggc ttgtagtaaa cagatttctc
     2581 tttaaacgca attttaacga ctgtttgctt tttagagtga ctgtcaccaa gtgaaaaggc
     2641 aacattgctt aggggctcac taatgttaaa gcacgacttt atctcagata agtcttctaa
     2701 aaatctatca aataataaag aatatgattc ctctatcagt cctacttctt tattaatttg
     2761 ttttagcaaa tacggatacc tgtcaaaaaa atgatttatt ccgttttctt ctcttatctg
     2821 ctgtatatac tgctcatatg cctctgactt attttcaatt tccttggaaa aatgatttat
     2881 atctaaaact agtgttttca tcgaaaggaa catgatcgtt tcaaataact gattttcaaa
     2941 ctcactataa aataacttat gtgtcttttt ccttaacact tcactggttt ctctaataga
     3001 agtatctaat atgtcatagt caaaaattga gttaaagtat tcgtaaaact gatgttgctg
     3061 atactctaac tttaattcat ttctttttat cattttttcc taccactact taaaaatcct
     3121 gcctagactg agtctaaaca ggaaattttt agtctgcttg tccagattgt tttaattaac
     3181 aacaaacaaa tactgagttc ggacagtcat cagtaatagt tgcaaaccaa ccggaacctt
     3241 ttttaccacc agctacttcc ataagttctt tttcagaaac ttcttcgata gcattagtca
     3301 aaatatcctt tgaatttttc ataaaactca ttctcctttc tatcagtatg tagtgactat
     3361 tttctacact tttattgtaa ataatacgtc ttcattttca atgagtaaaa agtgcaaaaa
     3421 tgactttttt catatttttt agtaagattt ttgagatgtc acataagagg tcactttata
     3481 acaaatagcc ctctgatata aaaaacaaaa ctcgttcttt acagctattt tacaatctaa
     3541 tcgcttctcg ttataacatc aatctctaat cagaaaatgg ttactttact tatttaatca
     3601 ggtcaggagt ttgaatgaca gaagtcaaat atctgaaaaa ggatgttaaa taaaactttc
     3661 aaaacccatt ttcatcaact aaaaacactt ataacccgat cttacaacta atggattacc
     3721 atcaacagca aataatacta tgcttgaaaa atgtcaacat catctacttt ttgtgactat
     3781 aattcagtaa acgaacatga cgtgtaaaaa tgtattaaag aagtatctca aaatcattca
     3841 atcacttgag tttctgctac ttttttatac cagtaggcac tcttcttagg ataacgttct
     3901 tgagtttcaa aatcaacata gaagagaccg taacgttttt catagccatt tgaccatgaa
     3961 aagacatcca tcagtgacca cataaagtat cctttaacat ttgcaccatc agaaatagca
     4021 tcagaaataa cttctaagtg ttttttcaca taatcgatac gtccaccatc atagacagta
     4081 ttatctacaa actcatcttt gtagccaaga ccattctctg taatgtaaat tttcttgtaa
     4141 ttaggataat cggctttgac acgcatgatt tgatcatata agccttgtgg gaagataatc
     4201 cagtcccagt ccgtttttgg aacatcaacg ggtgcttttc ttcgaccaac acccttgatt
     4261 tggtatttag agctgccttt ttcacccttg ccattgtgaa tgatttcagt ctcaccatca
     4321 aaagcttgca tccaatcact catatagtag ttaataccaa ggaaatcatt caaatctttt
     4381 gcggcgtcta gtgcggcaaa atcttcttcg cgaagatcaa gttcaccgcc attcacctca
     4441 aggatatggt taacaccttc cattgtttta tctgaatact taccaagata agtagcatca
     4501 aggataaatt tattatggat gatatcttca agttcagctg ctctaacatc atcaggattg
     4561 ttagcgtcaa atggatactt agttggaagt gcatggacaa caccaatttc acctgaataa
     4621 ccactatctt taaagagttt gactgcacga gcatgagaga ccatcatgtt atggtgtgat
     4681 tggaaaactt tagcaagatc atattggata cctggaggga atttaccaac taagtattgg
     4741 ccatcaccaa taggcccaat ttcgttaaat gttgtccaat agttaacttc tgagaattct
     4801 ttaaaacaaa attctgcata atttacaaaa tgttcaatgt tctcacgatt gaggaagtca
     4861 ccatccgagt ggagagcttc tggggtatca aaatggtgaa gtgtaacaaa aggctcaaca
     4921 tgacgcttat gacactctgc aaaaagattg tggtagtatt ctactccttt agggttaact
     4981 tctccttttc ctgttggaaa aatacgagac caggcaatag agatacggat gccgttgaca
     5041 ccaaattctt cactaagttt caaatcgaca gggtaacgat tataaaaatc acttgctggc
     5101 tcagctgtgt accaatagtt gtcttctaag tatttatccc aagctactgg tcctttacca
     5161 tctgtgtggg tagcgccttc agcctggtaa gcagctgtag caccaccaaa aataaaatct
     5221 ttaggtaatg ttttagtcat ctcagtttct ccttgaatat ctttcaaaaa taaagttccc
     5281 aaaacaattt ttgtgtttga gaactttacg acatttaaac tgttttctta attttcaaac
     5341 tgtgctttta caaaatcaag agctccttga ccatcacggg tcaatttgat gtattgagcc
     5401 ccttctgttt tagctaattt aatatcaagt ttatcagttt ccactttcat atcttcatag
     5461 ttagaagcta cttgaggtgc aaggataaca agttgatatt gtggtaaaat ctcacggtga
     5521 gcaccataac ttcctgctgc tgcagtgaca ggtgcaccat attctttagc tgctttattc
     5581 aaagcatttg caagcaaacc acttgtacca ccaccggcac aaagaacgag aacattagtt
     5641 tgatcagtga tttctttggt ttctttagct gctgattttt caagaatagc atcagctttt
     5701 ttagtatcaa agtttgctgc tactttttct ttgagggcat ctgatgaatt cgtacctgct
     5761 gcttcttcag caagaatttg ctcatcatat actttcaaga atgggtagta gatgatcaca
     5821 tcaacgacaa ttaacaaagc tgccaaaatg aatgctagaa cttggaagtt tgtaccaaga
     5881 atgagaccta atggagctgg tgtagtccaa ggtaagtttg cagtgaaact gttcattcca
     5941 agtgtgtcaa tgaagaattt gaaaatccat acgttgacaa tcggtgccaa gataaatgga
     6001 ataaagaaaa ttgggttcaa aacaagtgga gcaccaaaca aaatgggttc gttaacacca
     6061 aagaatgttg gaacaactga tgcacgtcca atggctttgt tacgttttga ttttgttaac
     6121 cacatgaaca tgaatggaac gacgagagtt gcaccagtac cacccatggt aacgatgaac
     6181 atttgagtcc ctgaagtcaa aatcttgtca gcatgttcac cagcttgaag taattgaagg
     6241 ttggtttcag catttgcgta agtaatcgct gcaatggctg gttcaacaat agatggtcca
     6301 tgaataccaa caaaccagaa gaaagcaaat gcaccgaaga taatagtgat tccaacataa
     6361 ccatctgctg cttggaacaa tggtgcaaga agtttaccaa ttgactcggc aacgttaacg
     6421 cctaaagtag tatgaacaat caattcaatc acataaagaa gtacaactga taatgtaaat
     6481 ggaatcaaat ctttaaaaac ttgagatata tttggtggca cctcttctgg catgcgaata
     6541 gtaacattgt ttttcacaca ggctttatag acatttacgg taataaaagc tgcgatgaag
     6601 gccgttaaca aaccttttgt tcccataaat ccagttaaga aaccaccgtc ttttgctgga
     6661 tttgctgcca taagtaaaaa acctacaata gcagcaagca tggttgaaat aaagttgatt
     6721 tggttagtgc taggcaatga gcggttcatt gaatcggtta atgcttttgc agtcgtacca
     6781 gccacaaaca aacctaaaat acccattgag tagttgtatg gcgtcatcaa gagattctca
     6841 atatccttac tccaatggaa gccccatgca tttggaacat aggcaatcaa gataaagata
     6901 cttgaaaaca agataacagg cataccagcg ataaaaccat cacgaatagc gcgaagatag
     6961 atgtttcgag aaattttctc gaagaaaggt ttccctttct caatctgagc aattaatcca
     7021 ttcattattt tgctcctctc ttataaagtt caatcatgtg tttcattaaa tcttgtaata
     7081 aaatggtcgt cattaaatga tcttgaccat gcattaaagt gacactataa gctaagtcat
     7141 ctccagctgc ttctttttgt agtagacttg tctgagcatt gtgagcatca ttcaagcagt
     7201 cactacctgc agcgattaat tcttctgctt tagcataatc tccttcttgc gctgctttaa
     7261 gcgcttccaa aaattttgaa cgggcatcac cagcataggc tacgatttca aaacctaaaa
     7321 gagtagtttc ttctctattc attgtagttt cctccgaaaa taatgttaca ttttttcagt
     7381 ccaaggactt gcagttttat ctagtacttt gtttaattcg tcaatatttt taaaaccttc
     7441 tgtacgcaac cattcacgag ctgcttgtgg tccttcttcg atatagactt ttacagatcc
     7501 tgcccaggta gcacgtccac ataagacacc gttgaattta gcacctgatt ctgctgcaaa
     7561 caccaaagta tcttggaaca atttggcaga aacaccagca ctcaaataaa tgtatggtaa
     7621 atcagtagaa gcttcttggt cacggaaagc ttgagctgct tcttcttttg taaagagaac
     7681 ctcaccatct gcaaagcctt ctacaaattt catatttact ggaacttcaa ctttcaacac
     7741 gtcaactcca aagcgctctt ttgagaaaac tttcattgct tcgttaactt tatgagcttt
     7801 aacttttgca aactcagggc ttgcattgtc agcaattttc tcatcataag ttagaatttc
     7861 taagtagaat ggaatatctt ctgcacggca ttcagaacca atacgttcaa tgtaagcttt
     7921 tttctgctcg ttaacatctt gatctccatc aatatcatag taaagaagga atttaactgc
     7981 ttctgctcca gcttctttaa tacgttttgc agaccaaaca tctaaacaat caggtaagcg
     8041 actagttgtt gttgcatcgt atcctgtttt ctcatatgcc aacaacaagc ctgcttcttc
     8101 tgaacgaaca cgacttgctg gcaagccata ttcaggatca agtagaattg aggatgcaaa
     8161 tggtgttagt tcttcagaaa ctaaactttt aagctcttca atttgttcta ctgttggctc
     8221 ttttgtttga tgttgagcca tcatacgttt gagagctcca cgttggtcaa aagctaaggc
     8281 agaaataaca ccatctacac ttagtttttc catgcttttg cgtttgtttt cagttaaagt
     8341 aattgtcatt ttttatacct ctttgacttt aatagattga tataacttat cgtaatttgc
     8401 catgttaaca tgcccagttg ttttttcttg cgcatttaac atccctaaga catttgcttt
     8461 tgttaataaa gctcgatcat cttcatcatt cgctaaacct gaagcaatac ctgccactgt
     8521 agaatcccct gaacctacag cgcttacaat tttgatttta ggaatgtcaa cgttataaaa
     8581 cgtatccttg tgctttgcaa atacaccatc agcaccaaga gaaacgatta tccattcaat
     8641 tccatcaaat agttcatctt gtaagacttc ttttaaggca tcaaaatctt ttgtcatttc
     8701 tttacctaga agttgagaaa gttcttcaag attaggtttg ataactgttg gtttactatc
     8761 accttttagt actgcttcta gagcatttcc agaacaatcc agaaccgttt tcttaccatt
     8821 aagattggca atcttgatta acttctgata gtaatcatct ggcataccag caggcaaact
     8881 gcctgagagc gtcactacgt caacatcatt cagtaaatac ttaaaatgat gagtaaatcc
     8941 atcaatttca tctacactta acatcggtcc tttttctaaa atctccgttt gattaccttc
     9001 gtgtaaaatg gctatacaag ttctagtatc acctgaaatt ttatagaagc gacttaaaat
     9061 cgaatcagga agatgattaa tgataaaatc accgctttct ccacctacac aacctgtagc
     9121 tttgactgtc tcaccgaatt cattaagaac tcgggaaaca ttcaagcctt taccaccggg
     9181 tgtctttgta acgtctacaa ctcgattgac agtatcgcat tttagctcat ccaaagggta
     9241 ggagacatca atagctggat ttaaagtaac tgttaaaatc acaatagctc ctttttctat
     9301 atatatccct atagtaattt attcaaatat tagtcgtgat attcaccacg gtcccatttt
     9361 tctaggaatt catcaaagaa gtgtgggttg ttttgatctt ggctagcatg ttgcaagcta
     9421 tccatttttt caatccattt tttattttct tcagttggtt tgtattccgc ggccaagaaa
     9481 gcatcgataa tatcattcat caataaacca ccgataattt ttccaccaaa accaataacg
     9541 tttgcgttta gctcttcttt tgagtagata gcagatgtca tatctctaac gagtgctgaa
     9601 cgaattccag gaactttgtt tacagcattt gtgataccaa caccagtacc acagataaca
     9661 acacctagtt ctgcttcacc acttgctact gcttcaccaa cttttttacc aaaaattgga
     9721 tagtgtgtgc gaacattatc atacgtacca caatcaataa ctttatgacc ttgtgatttt
     9781 aggtaatcca caacagcgat tttttcataa gtaacaatat ggtcacaacc tacagcaatt
     9841 ttcatttttg ttctccttgt tttaacctat ttcaatcaat tagcacattt tattaagcat
     9901 gtcgacacga acttgatgac gtccaccatc atatttacct tcgacaaagc ctttgataat
     9961 gttctttgca attcctggag cactaatttc agaaccaagc gtgatgattc gagcattgtt
    10021 gtgtcctctt gtcatgtatg ctgagcgctc atctgatact tcagctgcca ccattccttt
    10081 gattttagta gctaccatga aagaaccaac accatatgca tcaatgacaa tacctaagtt
    10141 atcatcggat gcattaactt cttttacaac agctaaagtt gtatctacaa agtcacgtac
    10201 ttcgttttca ctaacatcaa cgacttcgta tttaccttct ttaaggtaat ctttgataac
    10261 ttctttaagt tcttgacctg ctttgtcagc accgataata attgccattt tatttctcct
    10321 atgatttaga ataagtaaat gtggaaaacc tacgtagata gttaattaac gatttgcaac
    10381 atcttttgaa ataacgcttt cattatttct atgacctaat catacaccca ccaaacataa
    10441 aagtcaacat ttttttgttt tatttttata aaaaataaac aaaatatgtt tatttttttc
    10501 atttttacgt tattatccta atgtttcttg tgtttctttt tcatttcata aatcccttta
    10561 acagccactc gtaacctatc atatattacg aaacccttat ctctatttat tgtaaacgtt
    10621 ttatttaaaa cattttctat tttgttaatt tttgtttttt ctaatgttta tgtttgtttt
    10681 gtttgatttt tttattgata ttatgttatg atacctttaa tagttatacc ctaagacact
    10741 gataggagat aagaatgaaa aagaaagagc gtcatgaaaa aattctcgat atcttaaaag
    10801 ttgacggttt tataaaagta aaagatatta tcgatgaaat gaacatctca gatatgaccg
    10861 ctagacgaga tctcgataca ttggcagata aaggattact tatcaggacc catggtggtg
    10921 ctcaatattt ggattattct tcagcaaagg acgaaggtca cgagaaaaca cacactgaaa
    10981 agaaggtctt acagactacc gaaaaaaaac aaattgcaca aagagctaaa aacattatta
    11041 aagatggcga aactgtcttt ataggtccag ggacaacatt agagcatcta gctgtcgaat
    11101 tgaaaaatag aaatatcaga gttattacaa atagccttcc tgttttttta attttgcacc
    11161 cgagcactac tattgatttg attttaattg gtggtgaatg tcgtgaaatt actggtgctt
    11221 ttgttggtgc tattgccatt aataacctag aaacattaac attttcaaaa gcttttgtca
    11281 gcgcaaacgc agtttacaat aattctattg cgacgtacag tgatctcgaa ggagaagttc
    11341 aaagggttgc attgaataat gctgttgaga aaatccttct agttgatagt accaagtttg
    11401 aaagttatga cttctataat ttttaccaac tagatcaagt ggacttaatt gtgactgata
    11461 aaaatgtgac aactgatatc atagaaaagt acaagaaatt ctcaaaaatc ataatcgctg
    11521 acaagtaaag gacctactca tattaaaaag cacttcaggg tttagatata tcccctgtca
    11581 agtaaacagg gagcatatct gaaagtagtg tttgtgttat aaagaagttt cttgctaact
    11641 tattttctgt tttttttcag acttatcagt cttgtactgt tcctttttct gatgaataac
    11701 gtggaaatag gcagacagct atatatttca cctctagaat ggttgccatt actgtcatca
    11761 agacatgctt gttctttatc gtatggagta aagctttctt ttagccatca acatacctct
    11821 taagtagatt ttggttcgtt accatgtcta cttaagaggt gtcttcaaag cgctttaaaa
    11881 cgttgctata acagtatatt aacgttttga gaattgtgaa gctttacgag cttttttaag
    11941 acctggtttt tggttgatat tctgatatac ataaagatac ttataaaatc aacctattcc
    12001 tggttcaatc aatcaaaatc tattaattat atacaaatat cttattccca acggtatcaa
    12061 taaggtatca aaaataagtt tcggagctta tcaaataatg aaaatctgtc tcaattaccg
    12121 agtctttttt attgactttt ttgtatatat gatataatta aataagttac ataaaggggt
    12181 tacataaaat gactacagta aaaaaaaaca gagcggttac ctttcaagct aataaagaat
    12241 tggtaagcga agcaatgaca gtattaaaca aaaaaaattt aaccttatca tctgctttaa
    12301 gattattcct acaaaatgtc gttgtcacaa acgaggttga cttattgacg gaagaggagt
    12361 tagagaaaga aaaacttttc aagcaatttc aagctgaaat caacaaaaat attgaggatg
    12421 ttcgtcaagg gaagttttat acctctgagg aagtgagggc tgaacttgga ctataagaaa
    12481 tatcagatta tctatgctcc tgatgtttta gagaagctaa aagaaattcg tgattatatt
    12541 tctcaaaact attcctcaac atcaggtcag cgtaaaatgg agcaaatcat tagcgacata
    12601 gaaaaactcg aggttttccc agaagttggt tttgatgccg atgaaaaata tggttcaaaa
    12661 atcatccatt atcacagcac taaaggttat accttaagta aagattatat tgtcctatac
    12721 catatcgagg gggaagaaaa taggatcgtt attgattact tgcttcctac tcaaagcgac
    12781 tatataaagt tattcaaata acacgttaaa agccttagca gtcttgctag ggcttttttg
    12841 gtagattacc aattaactag gagcaaaatg agttcgggct gtttagtaga tattccacaa
    12901 agaagccaaa gactacgaag ctaggctaat ctaccttaag gcttcaggaa acttggagga
    12961 gttcaccaag ccaactcata aaacttatag cgagatattc gagaaatggt atcaagccta
    13021 tcaagatacg gtagagccaa ccacggcttc tcgtactctt gatctgtttc gacttcacat
    13081 tctgccagtc atgggagaat tgcccattaa caaaacctcc cctttagact gctagaactt
    13141 catcaccgat aaagcaaaga cctttaagaa tatcaagcaa atcaagtcct acactgaaaa
    13201 ggtctttgat tttgccatca agatgaaact gctcaagcat aaccctatgg ctgaaatcat
    13261 tatgccaaag cggaaaaaga cacgaataga aaactattgg acggttcaag aacttcagga
    13321 gtttttagcc atagtacttc agaaagagcc ttacaagcac tacgcactat ttcggctact
    13381 agcttatagc ggcagctatg cgctcttaaa tgggctaata tagacactaa gcgtcaataa
    13441 gagcctagga cgattagacg gacaggcaat cgaaaaaagc actaaaaatg atttctcagt
    13501 aagaaagatt aagctagaca gcgaaactat ttctattctg caagaatgga aagccatcag
    13561 ccaaaaagaa aagacacaac tagcagttgc acctctttca attaagtctg actttatatt
    13621 tacatactgt actagagaag ggagtattga accacttcat gcagactata ttaacaatat
    13681 cttatcaaag gtcattaagc aacatagtct taaaaaaata agtcctcaca gcttcaggca
    13741 tacccatgca accctgatga ttgagattgg agttgaccca gtaaatacag ccaaaaggtt
    13801 aggacatgct agtagtcaaa tgactcttga tacatacagt catgctactg cagtcggaga
    13861 agacaaatca atcaaacaat ttgctaactg tctcaaaaat aactaaataa acgtattaaa
    13921 ccaagtcaaa agttttccga aacggtatca aaagcaaaaa acgacaaaaa aagcaccttg
    13981 caagagactt gcaaaatgct tgtaatcgtt gatgtaaagc tgttcttaac gttttgagaa
    14041 ttgtgaagct ttacgagctt tcttaagacc tggtttttta cgttcaacca tacgtgcgtc
    14101 acgtgtaaga aggccagcgc gtttcaatga atcgcggaag tctgggtcta cttgaagaag
    14161 cgcacgagcg ataccatgac ggatcgcacc tgattgtcca ccgtaaccac caccaacaac
    14221 gttaacgaaa acgtcgtatg aaccttcagt tgatgtaact gcaaaaggtt ggttgatgat
    14281 caaacgtaag tcagcatgtg ggatgtattc ttctacatct tttttgttaa cagtgatttt
    14341 accagtacct ggaaccaaac gaacgcgtgc aacagcgttt ttacgacggc cagtacctgc
    14401 atattgtgct tgtgccatta tttaatgctc ctttcctctt agataagtcc tgagatgtca
    14461 agtacttctg gttgttgtgc tgcgtgagta tgctcaccgc caacgaagac tttcaatttc
    14521 ataccttgtg cacgtccaag agtgttatgt ggaagcatgc ctttaactga tttttcaatc
    14581 aagcgaactg cgtttttaga gcgaagttca ccagcagtga ttgatttcaa accacctggg
    14641 tacattgagt gagtgtagta aactttatca gttgcttttt taccagttaa tttaactttt
    14701 tcagcgttga taacgataac aaaatcacct gtatcagtat gtggtgtgaa agttggtttg
    14761 ttttttccgc gaagtacgct agcaactact gcagaaagac gtccaagtgg cacatcagtt
    14821 gcgtcaacaa cgtaccattt gcgttcaact tggcctggtt tagccatgaa agttgttttg
    14881 ttcatgattt ctcctatacg aattcgtaat atttgtttac aaggtgatgg gtgttccgtc
    14941 ccatcgaagg tatttggaag gttccggggc ctttcaaatg gggtaaacaa taccgcctac
    15001 tatgatatca aacttaagag gctccagtca agtgctttag ctgattttat tggattattt
    15061 tttctttcga tttaggagaa tggcagagct gctctgctgg tgttaacgag aatcatcagc
    15121 ttcccaaaaa aggtcatcta aagtcttatc aagcactcga caaatggcaa tgcaaagatt
    15181 aatcgttggg ttgtaatcac ctttttcaac agccgcaatg gtttgtctgg agacgcctac
    15241 caaatctgct agagcttgtt gagacaaatc tttgcctgca cgcgctgctt ttaatttgag
    15301 gttcttcatt catctgcctc tttagcatcc agataatgac gatagaaaat actagctccc
    15361 atactaaggt tacaatatgt cgtttgaact gccaaccctc cccaaagagc caatgtaaag
    15421 aggaagcttg cagataccag tccctctgtg aatcggctaa taaagagtga cagccagata
    15481 accacaatca taaaccaaaa cccaatagtg tatcctttga gaagaatctg tttttggcgt
    15541 tcatcatatt tgggcaactt ctgatcgtcc cttaccttag aatctagtac ttccttgctg
    15601 tctagtctcg tttggagctt tttcgctgtc tttagccccc ataccaacaa tatgagaaag
    15661 ctagtcaata caaaagctac gcctccaact aagtaacgtt gaaaactggt cttagccagt
    15721 aatgttgcta ctatcacaac tagatccatc actgctgtta tgacaatgaa accccattgt
    15781 gacttagcga gattttgttt gctatcaaac atgattcgtt tctcctttaa atctttatat
    15841 gacataatat aaattatttt ggatattttg tcaaatatat tttacataat tgattgactt
    15901 aagcagcaaa aaaggattga ggatttctct tcaatcctta taagggatta acgggaattc
    15961 tgcccaatca caaaaactgc cagggtgtta ggaccaacgt gagctgagat aactggtcct
    16021 agtggcatca taagaacatc gctaatattc tcatgcgcca gcagctcttc tcgtaacttt
    16081 tcggcactac cctgatcgct tgtataagag acaataaccg tcgaatccgc aatatctttt
    16141 tccacttgag ccaccatttc tttgatggct ttttggcgtc cccgaatttt tgcaatgggc
    16201 accaatttcc cttcctcatc aatccacaaa agaggtttga tactggctaa actgcctaga
    16261 aaagctgaac cttttgacag acgcccacca cgcatcaaat gaaaaagatc atctactaag
    16321 aaataggtgc gcagtcgagg gatcactgct tcaacaatat ctttagtctc cagtaaattt
    16381 ttgccactat ctctggcttc tgctgctaaa atggttagat agccttctcc tcctgcagca
    16441 gccaaggtat caacaatttc aatcaccgca tcgggataat cttctcgaac aagatcgcgt
    16501 gccattagag cgctttgata ggtacccgat aaaaccgaag aaaaagcaag ataaagcagt
    16561 gctttgttgt tcctagcatg ttcacgaaaa accttctcaa actctcccac attaatctga
    16621 ctggtttgag gatgactgcc agctttcatc tttttcaaaa ggtaatcact actaatacgg
    16681 ttaggaccga ccgtttcata aacctctcca tcgcacaaaa tcgttaatcc tataaggaca
    16741 atatcatgat cttctgccca ggtttgattc aaatcagcgg ttgaatctgt cattattgta
    16801 aaggtcattc ttacttctcc tcatccagtt ttttagtttg ataatcaaat aattattgtt
    16861 ttattttatc aaaaaaaccc gcacttggcg agtcgtaatt ctcattatcg atctaactga
    16921 gacataaaat ccttcaattg aataagctgt ccttggtcaa aaggccgcag tttaggcgtt
    16981 ttgagatcaa tatctctaga cattttatct aaatcagctt tgacagtatg aactctttgc
    17041 tctaattctc ttgcagtgac acgaagagct ccttgagaaa aaatcgtcca ttgttcattt
    17101 aaatcactcg tagctacttc taccatatgt atagccgtat ttaactctgc tgccatgcgc
    17161 tcaatgtagc tatctgctgt ttcgtcttcc tctgtaaata ccactgagat ataatactgg
    17221 tcatatcgtt gccttaaccc cggtacatat tgggcatcaa aaacacaaat aatattaata
    17281 ttctcaaaat gggcataatg attaagtttt gttaaaagtg tgttacgtgc ctgatcaagc
    17341 tgatttgtct taaacaactg acgggttgat tgccaaaagg caatcatatt atacccatct
    17401 actaataata tccgtttttt cataatttag cgcctatttc ggaaaacttc atacatgaga
    17461 atagctgccg ctacgctagc atttaagctc tgtacgtgac cattcatagg aatcgtaatc
    17521 atttcatcaa cttgcttttt gatattggta gagatgcctt taccttcgtt accaatgact
    17581 aaagcaagtt taccattagt gttccagcaa tcagacggtg ttccattcat gtctgtgcca
    17641 aaaatccaga atcctcttgc tttcaattta tctagagttt gactaaggtt agttactctc
    17701 gctatcggaa tatgttcaac agcacctgta gacgtctttg aaaccactgg agtcacacca
    17761 acagaacgat gtttaggaat aatcactcca catacatttg tagcatcagc tgtccgtaaa
    17821 atcgatccta aattatgagg atctgtcaga ccatctaaaa taagaatcaa aggatttgct
    17881 tcttgctctg ctatttcgag gatctcatca acatcagtat aggcaaaagc tgatactctc
    17941 agaacaaaac cttgatgcac agctccatca gtcatttgtg acaaggtttt tttaggcgtc
    18001 catgaaatag cgaccttttt ttgtgtcgct aagcttttga tgttatccac tttctttcct
    18061 cttaaatcct cttggatata aagcttattt cctgtatttg cttgaaggct ttctgtaacg
    18121 gcatgaacac catagacgat atcgtttgtt tcaatagtat ctttatcttc catgagttta
    18181 ttataccatg aatgcttcaa aataaatgca tagactcttt tattttcgtc tagatacttt
    18241 ttgaatagct ataaataaac ctgcagctaa actgactact agacctaata agacccaagg
    18301 gaatcctctt tttgaagtag gttttacttc ctctttgtcc actagcattt ttgtcttgtt
    18361 gctaccgttt ttttggctat tactagcagt tggtgtaagt ttctcatttt tagtagatcg
    18421 ctttaaggaa gttgatcgat gattagtagc tgatctgaaa ggatttgaag tagaatctat
    18481 ttcttggtta gctgattgat ttgtttgagc ttttgtgtct acatcgactg aattcgtcat
    18541 tgctttagaa gtatcctttt gttgcatatt agttggtgtt tttctagctt tgttttgatc
    18601 aaaatgaaca gttcctgatt gaccagttac tgccttttct tgagtatgaa cggtgacagt
    18661 tacatgatag tcaccactct tttgtccagt taaatcaaac caagctgtaa aacgacgctg
    18721 ttgcgctgcc atagtatata cccaactatt aatagtatta tcactagcgt ctttaagtgt
    18781 tatcgttgcc tgagttggtt gtctgacagg ttgatctgtg gtgactgtag catcaatata
    18841 aggttctgtt ccacgcatac tggcttcaac actgacctga ctaatagttg attcagctat
    18901 aacattatca gtgtgctgat cttgtgcata cacagatatg gctttgccag aagtccccag
    18961 caaaccaata agtaaagcta gtgataataa gctaattgtt ttttgcatag ttgtcataat
    19021 aaatatctcc tctttaaatt aatcttaccc tctcattata aactattcga aaatgatttc
    19081 attattttta tgtctttttt gttacaaatg tatctttttt atatcattat gtctttttga
    19141 tgtcataaaa agacttaatg gctctctacc tttacttcag acctatgaaa ataagagtct
    19201 cctaggggac tcttatgagg atatcaattg ttgcttttct acatactcaa tacaccatct
    19261 gatcaattct tctaaccgct ctttttggcc catcatatca agataaccca taatggcttc
    19321 aaaacctgtc gacatacgat aggtaataat atcggcattc ttagctttag tatggctatt
    19381 ggtattgcga ccacgcttat agatgtcttc ttctttttcg gtcaatagct gcgcttctaa
    19441 catagcctga atcaagttgg cttgtgcctt agcagaaaca tatctcgttg ctaaacggtg
    19501 tagctggcta ggtttcgttt taccttgaaa aatgagatga cgacgaacat agtaggaata
    19561 aaccgcatcc ccttcaaagg ctagggcaat gccattaatc aaattcacat caactggatt
    19621 agtcacgcag ccacctcaca ccatctttgg tatctagcag cttgatgcct tgaactgcta
    19681 actgatctcg aatggcatca gctgtggcaa aatcacgatt cgcgcgtgct tcttgtcgct
    19741 tggcaatcaa ggcttcaatg tcaacctcaa gcacctcttc ttcaaagata atgccaaaaa
    19801 cagctaacat tttctcaaaa gcgcttttaa caggttctgt ataggagcca gaattaatcc
    19861 acttggccat gtcaaatacg acggtaatcc catttgctgt attgaaatca tcgtccatag
    19921 cgtcttggaa agctattaca aactgtttta gctcttgctc atctgcagtt tctgtcagcg
    19981 gttgttgcaa ggtgttttta agatacttca gattgatttc cgcatcatga atagtctttt
    20041 cagtgaagtt aattggtttt cggtactgtt gtgtcgcaag aaagaatcgc aaaacctgac
    20101 catcaacggt ttgtaacatg tcatgaacgg tcacaaaatt acctagtgac ttggacattt
    20161 tttcgttatc aacagtgaca aacccattgt gcatccaata gttagcaaaa gtcttgcctg
    20221 ttttggcctc agattgggca atttcattgg tatgatgagg aaattccaaa tcagctccgc
    20281 caccatgaat atcaatggta tcaccaagaa tttcagtagc catcacagaa cattcaatgt
    20341 gccagcctgg acgaccaaac ccccaggggc tatcccaaga aacctcacct gccttagctg
    20401 atttccaaag agcaaagtcc agtggatttt cttttaaagc tgtctcagca tctgttcgac
    20461 cactggctcc aacttcaagt tctgacaggg ttttattagc tagcttggca taatgctctg
    20521 acttttccac gcggaaatac acatctccat ctgcttcgta agcaaaatct ttttcaatga
    20581 gactttcaac aaatgaaatg atttctgcta tataatccat aacacgagga ttttgtgtgg
    20641 ctggcttaac accaagtgcc ttggtatctt ctataaaagc tgcaataaag cgatctgaca
    20701 attctttagg agaaacacct gcttgagtag cagccttgat aattttatca tcgacatcgg
    20761 taaaattgga aatgtaattg acctgatagc cagtatactc aaaataacgt cgaatggtgt
    20821 caaaagcgac cgctgatcta gcatttccaa tatgaatata attatagacc gtcggtccac
    20881 aaacgtatat attgactgta ttttcagtca aaggtacaaa cttgcggagc gaacgggtca
    20941 tggtatcata aattttaatc atgtaaactc cttattcaat agtctggcat tagttgtcat
    21001 cttgatatcc taagtctttt tctgaaatgc tgttccacct tttcaacaat ttaatattaa
    21061 taaccaaacc tattaaccaa aatagggtca aaatgaagta tataatcgct ttaaccatgt
    21121 cttgtctcag taaaaagatt agactagcca ccagtgtaat actagaaaca agaatagaca
    21181 aactcataat gacatacagc ccaactctta ttttattcat gaggctcctt tattaacgaa
    21241 aaaccttcac aacctgtgaa ggcttcagaa agtagacaaa cccactttta tgctcaaaaa
    21301 gcatgaatag atctgctgat ttgacatcag gtttcctatt tctgcatgtg gggtgagcca
    21361 aaacagctgc tttttgttgt ggtaaaagtg gtatcaatac tgacagtgat gcccatacag
    21421 atttttgaga ccttaggctc aaaactaagg catggaattc caaaggaagt cgctgccgta
    21481 agcaccacct gagaaaaagt atcacaatag actgtttctt cagtctaaga cttgcttagt
    21541 tgatgctctt ttacgtgttt tttgtatttt gtaacattcc catatcacta cactcagcaa
    21601 ccaaactgat agggctagct aagttcaaca ttactctact agaaagtccc aaaatatttt
    21661 atcggaagtc atcagtgctt ctttttgtta ttttccgatc attttgacaa ctgataagag
    21721 acctctcgtt gtttttgtaa actttgaatt tgacgattat ctttttgccc atgcactcgt
    21781 actatcttag ctggcacacc tacaactgtc acgtcttcag gaacatctga taacacaaca
    21841 gctgctgccc ctactttagc atttgctccg atgtcaatag gtccaatcac ttgggcatgt
    21901 gccgaaatta aggcaccttg tcgaaccgtt ggatgacgct tgccacaatc ttttccggtt
    21961 ccacctaggg tcaccccatg ataaagcatc acaccttttt caacaattgc tgtctctcca
    22021 ataacaagac cagcaccatg gtcaatgaag actccaggag cgatttgtgc tccaggatgg
    22081 atttcaattt gtgtccaaaa tcgccaaaat tggctatgca ttctggctag taatttaaaa
    22141 tgatgtcgcc aaagaaaatg agacaaacga tgagcagcta gggctttgat gcctggataa
    22201 gttaggataa cctcaagact attacgagca gctgggtcta gagctttaac aatagctata
    22261 ctttctttcc accaacccat actaactcct acgacttatc taattctgac caatcaacaa
    22321 gaatttgttg gtcatcaaaa ggattgatgg cgacaccgaa cgtttcatca agctcgtttt
    22381 caccatttct tggttgataa atatcatcaa tcgtccaagt cagaatcact ccttcagctt
    22441 tcctgaaaag gcctccaaaa tcgtcttggt tgtaccattt cgcaaagctt tgaagatttg
    22501 aaaaggcggg aacatagctt tttccttcag gcgttgacat ggtaggaaaa aggcggtcgt
    22561 aatggttatt atctttagga taaacaaagg caggaacaag gtaaaccttt tccatcgtat
    22621 ctgccgccac attgtcatca ctcataagcg tatttaacac agtggtgtaa tggttcataa
    22681 attgaatcat atcactgctt ttgaaaatgg tagaattccc aaaatctccc tttttcttaa
    22741 ggttaaagat aagacctgct gcaccagatg taatgacttc ttctagcact gcaagagctg
    22801 aacgctccag ccaatactga ctttgagcac tcttttgttc ttctttaaag cgagccatat
    22861 cttccttatc ggtaaaaaca ggggtaacct tgacaccttc gacttctatc acgtagggtt
    22921 ctttagcagc ccagacagga aaattatgga aagcgttgac aagcgcaagg ctatccaaaa
    22981 agttatcagg cgcattgata aaagctctta agcgaatatc taattcattt gatttagtca
    23041 tgtttttctt cttttttctc tggttttggt gggcgtggaa tcaaagcttt cattgaggca
    23101 tccacacgac ccttctcatc aatcttaatg accttaacat caacgtcttc acccacttca
    23161 aggacatctg acacgttggt cgttctcgtc caggcaattt cagaaatgtg aacaagagca
    23221 tctgtcttgt caaagaggtt gacaaaggca ccaaatttct caatacggac aaccttagca
    23281 tggtaaactt cgcctacctt agcttcacga acaagacctg caataatttc tttagtgcgg
    23341 tcaatggcag cttggtcact tgagtagata gagacatttc cttcgtcatc aatatcaatt
    23401 ttgacacccg tttcggcaat aatcttgtca atagtttcgc cacctttacc gataaccact
    23461 ttgattttgt ctacgtcaat cttgatggtg tcaattttcg gtgcagttgg ggctaactca
    23521 ggacgtggtt cagcgatagt tgcttcaatc acatcaagga tttcaaagcg agctttttta
    23581 gcttgtgcaa gagcttcttc taggatttga ggggtaattc ctgcaatctt aatatccatt
    23641 tgaagggctg taatcccttc acgagttcct gccactttaa agtccatatc tccaaagtgg
    23701 tcttcaagac cttggatatc ggtcaagact gtataattcg tcccatcgga aatgagaccc
    23761 atggcaatcc ctgccacagg cgctttaatc ggcacaccac cagccattag ggcaagggtc
    23821 ccagcacaga tagaagcctg agaagacgaa ccgttagatt ctagaacttc ggcaactaaa
    23881 cgaatagcat aaggaaactc ttctaagctt ggcaagactt gttcaagagc gcgttcacct
    23941 aaggcaccgt gtccaatttc acgacgacca gcagctccgt aacgacccgt ttcaccaact
    24001 gaatattgcg ggaaattgta gtgatgcaaa aagcgttttt tgtactctgg ggccagacca
    24061 tcaatgattt gagtttctcc cattggtgcc aaagtcaaaa ctgacaaggc ctgcgtttga
    24121 ccgcgcgtaa aaagacctga tccatgtact tttggcaaga agtcaaccac agcatcaagc
    24181 ggacgaattt cgtcaatctt acgaccatca ggacgaatct tgtcttctgt aatgaggcgg
    24241 cgcacctcag catgctccat ttgttcaagg atttctgcca cgtcacgcat aatggttgct
    24301 aggttttcgt cttctgcgta acgctcttcg tattcagcct taaccatttc tttaacggct
    24361 tctgtggctg cttcacgcgc ttttttctct tcaacttgaa cagctttttg cagttgagca
    24421 ttgtacttag ccacaatatc agcttgtaag tctacatcaa cctgtaacag ttcaacctca
    24481 gctttttctt taccaacaac tgctacgatt tgttcttgga aggcaattaa ttcttgaata
    24541 gcttggtgac cttttaaaag agcctcaagc atgatgtctt ctgataattc tttggcacca
    24601 gactcaacca tattgatggc ttctttgcta ccagcaacag ttaattctaa gagtgatgct
    24661 tccatctgtt ctttatctgg gttaatgatg aactcgccat caatatagcc aacttgaaca
    24721 cctgcaatcg gtccattaaa tggaatatct gagattgaca aggccagaga tgagccaaac
    24781 atcgctgcca ttggagcgct agcattttca tcataagaaa ggacagtgtt aatcacttgt
    24841 acttcgttac gaaaaccttc ggcaaacatg ggacgaatcg ggcggtcaat caagcgagct
    24901 gtcaaggtcg catctgttga agggcgtccc tcacgtttca tgaaacctcc tgggaattta
    24961 ccagcggcat acattttttc ttcgtaatta acttgaaggg ggaagaaatc acccgttgcc
    25021 attttcttag acataacagc tgcggtcagg acagttgagt cgccataacg aacaacggtt
    25081 gccccattgg cttgcttagc gacttgacca acttcaacaa caaggggttt ccctgcaaat
    25141 gttgttgtaa aggtttgttt tgacatatat tctcctttta attttcagag gggtaaagag
    25201 gtacctgttc tctgcttaga ttcagttgtt atacgttgtt ttgctacaaa aagcaacctg
    25261 ccacgcttgt cacacgctcc tctttgtatc aaacgacgta tctgctacat tttaccataa
    25321 aatactagaa atttcactgt cagatcgcaa tctcttgaaa tgtccttgaa aaatattaaa
    25381 cgaaacttat actctttaac aaagcaaaaa aaagcaggtt ggtatgcctg ctttcgtctc
    25441 ctaatattaa tgattgtaat cctctaaaat tttaaagccg aggctggtac tgtctttcag
    25501 aaacatttgc acggtttcaa gggaatagtc ttctaaatct tttccttgaa gaggcaactt
    25561 ggcaatcaaa tcagtggtac aagtgataat gtccacgcct agctgatcag cttgatagat
    25621 attataagtt tcacgaggac tagcccacaa caattcgacc ccttcttttt gacgacaaat
    25681 gcgtagagct tcttccatga ttggcattgg gtcaacgccg gtatctgcaa tacgaccagc
    25741 aaaaacagac acaatagctg gaactcgagc ggttaaatga tcaaccacag cttgagtctg
    25801 ctcaattgta aaaatggctg tgacgtttaa cttaatgcct ttggctgaca acttttgaat
    25861 gaggggacag gttgattctc ctgttgaagt ggtgactgga attttcacat agacattgtc
    25921 acctagactg gcaattttct cagcttcctt ttccatgctt gcgagatcat ccgcaaagac
    25981 ttcaaaggac actgggtagt ctgtaatttt ggcaagcact tctttggcaa agccaatata
    26041 agaactgatg cctgcttttt tcatcaaact tggattggtt gtaaagcctg tgaccaaacc
    26101 tgtttgtaaa tcctttaaca tggtctctaa gaccgcaccg tctgaaaaga ctttaacgtt
    26161 tagttttttt gtcatcatat cctcctttta gatttctact gaaacattat tgatggcttc
    26221 ttgagatttt gacagaaagt ttggaagcac caatacaata gcaagcacag caaccaccaa
    26281 gtaaataccg atttgaccaa tcgacgttcc taagcggccc agtaaaatcc ctaaaacacc
    26341 gaaatccaca tctccaaagg tcgtgtttga aaaaccaagt ttaccaagta caggtagaag
    26401 catggctggc aagaaggcga gtaataagcc attagcgaag caccaatcat cgcaccgcga
    26461 cgaccacctg ttgaatttcc aaaaatctct gctgttgcac cgcagaagaa atgaggcacc
    26521 atacctggga taatcaggac accacctgca actcctaaaa tcaacatccc aagtaagcca
    26581 ccaacgaaac ttgacgcaaa accgatgata acagcggttg gcgcataagg gaagaatacc
    26641 gcacaatcca cggctggaat agcatttgga attaatttgt tagcaatacc ttggaaggct
    26701 ggaatcaagt cagccaaaat catgcgaaca ccggcgtaga caattgccac accaaccgca
    26761 aaggtaagac cactcttaat ggcaaaaata aatgggtttt gacctgctgc taattcttct
    26821 gctactgaag cattcctcaa aacagaagcc actgttgcca ccaagtagaa aatcaccatg
    26881 ataagtcctg ttgaaatggt ggtgttgcgc aagaaactcc atttttcaga aatctgaagg
    26941 tcttcggtat ctttactgtc tttgccaacc ttgctaccaa cccaggcaga aaggtaatag
    27001 cccaaactac caaagtgtcc catagcgatt tcatctccgt cagtcacttt cagagtatac
    27061 tgttgaccaa tggctggcga aatagctgac caagctccca agaggaaccc atctaagata
    27121 atcaaaagac ttcctttgaa accaacagct ccaagcacgg cggacaagag acaagccata
    27181 aagaagctgt gatgtcctgt taagaaaatg tatttgaagc gggtaaaacg agcaaaagcc
    27241 aaattgagca ataacccaac caccaagatg gacatagttt ccacacccag aatcttttga
    27301 gcgacagaag tgacggcttc gttatttggc actacgccag tgatgctaaa accgtgctca
    27361 atgagtttgg caagagggtc caaattggtc acaataacac ccgcccctgc aacaagcata
    27421 aggtatccca aaatcggccc caaggttcct gtcaacacct tatgagcagg tgttttcaaa
    27481 gccaccaacc ctgcaaaggc aatcaagccc attaaaaatg caggttcttt taaaatatct
    27541 cgaataaatg ataataatgc ttccatagta tcttcctatt tcctttaaag gcttattcct
    27601 tgccactcat ttccttgaga accggaacca aatcttcttc aattttttta cgattggtat
    27661 agcttttaac gatacaaacc ttggcatcct ctggaaaaat atctttaaat tctttaacgg
    27721 taacaaacaa atctgcaccc tttccaacag ccgcattgga atcacaggat tctgcatcca
    27781 catcaatacc caaactagag gcgatagctt ctactttcat gcgaagtaac aagctactac
    27841 caataccgtt tccacaaacc gttacaattt taatcatgtg attcgtctcc tttttcaatc
    27901 atatggctaa tcagactcat tatttcctca gtattcttag cctcaattaa ttgctcaata
    27961 tgttcatcat catctaaaat caacgacagt tcctgcaaag ccttcaaatg tgaactagaa
    28021 tccacagcag acaaaacaaa aatcaattgc acttgcttgt ctggatcacc ttcttgcttc
    28081 aaatcaaagc tgacaggttc ttttagttgt aagagagaca tgcctaactg ccgcgttcct
    28141 ttttcaggcg ccgcatgagg aacagccacc ttaggggcta aaacaatata ggccccaagc
    28201 tcattgaccg aatcaatcat gccatcgata taagatgttt caatcatctg gtgttctagt
    28261 aaaggctgag cagccaaacg aatcgcttcc tgccaatccg aaacagcatc agcctgccta
    28321 ataaaatctg ctgttaacaa gtccaatagt cctagacctc ctttttcaat cgttaaatgg
    28381 ttaccaatca ggtaacggga taaatcacta acaagtcctt ctttattagt aatcgtggta
    28441 tgtttatgaa taatactcaa cagatcatcc aaagcgaatt gctctgacaa gggaagatga
    28501 aagtcatcac agaccatctt tttcaacatc attttttcaa caggtcccat caaagcttgc
    28561 gtcacataaa caggtttagc acagtcaaaa gctactgttg aaaaaatcaa atcaaaggat
    28621 gctggatcca acaactttat tttgtccagc tggtgaatcc taataaactg tagctgtgga
    28681 aaaagttcct tcaaggttgc ctccaacatc agagacgaac taatgccatt agggcaaaca
    28741 gataaggcta ccagctgatt gcttggcctc ttcttagggg cctgcaacca tctcccaaaa
    28801 tgaatggtaa aataagcaac ctcatcttca ttaactgatt tccccaattg tttttctaga
    28861 ggagaaaggc tgcgcttgac caagtaaaag agagattcat aatcttgttt gatttgttcc
    28921 ttcaaaggat tggtcaagtt aatgtcgtag taaagtcggt aataagctgg caaaaggtga
    28981 ctgtataggt tctgacgaag ttctggggta tcggtgatag acaatcccgt gttaaccgcc
    29041 accgaattga tgatttcctc cataatgtca taaataggtt gctgaaagac taactctaag
    29101 tcaccttgga tacaaccaag taacctagat tgaaccaaat atttttcttc ggttagactg
    29161 gggaagttga ccaataactg gtccaccatc gtttcaacag ctggcgaagc taaaggaaaa
    29221 gtatccactg cttcagccct tacgttccgt gaaaatggtc gatgagcgag aaggcagaaa
    29281 aaataaatca aatccctcaa tttctccgaa ataaaagtta agtggttctc cctgctcagt
    29341 tcctccaacg ttgctgccat cacctttttc tggtcgggca aaccaagttc atgcaataag
    29401 taactgaaca cccaaggtcc agatgtgact tgcaaaagag aactgaccgc tgattctaag
    29461 agacgccgca aggctaaggg ttctccttca aaaaaataac catcctggcg attgtaagct
    29521 aaagttacct gaaaagcttg tacccgatca cgcaccaagt ttaaatcagc aataacagaa
    29581 tttctgctga gccgtaacaa gctttccaag tggttaatgg agataaattc tttagccatc
    29641 atgatgtaaa tgataatcat atccagacgc tcatcttgaa agagatagtc gtctaaggta
    29701 ggtagcatgc gattcaacaa gtccttttca gtaaggtctg gcggataaac cagctgcctg
    29761 tccagagcaa taaggggtaa ctgatagagt gacaacgtgt cattgatttt agcaatatct
    29821 gccagtatat gacgtttgct tgcctttaaa atggattcaa atgcctccag tgaatgtcct
    29881 ttatatttag aaaagagttg atagtttctg atgagctcat gagatagcat gtcatctcct
    29941 cctataatgt cagtataaaa tgaagcgttt tcattttcaa gataaattga gtccaattgt
    30001 ctcatgtcat ttttgactgc aattggactc aacaggtgat atcattgtaa caagttcctc
    30061 aaaaggtggt caaaaatagg caaatctggg aattgattcc ctttttcttc atgatacaac
    30121 aaaagatacc tcatcactga gatacctttt gttgttaaat aaaatcatca actgctaaaa
    30181 aaacagtctt agaccattct agccaaatgt gtaagttaac aaacaacatg tcaaaaatga
    30241 aaaagcccac tgcataagca gaggactttt taaacttgaa attaacgacg aagtccaaga
    30301 gattggatca actcacggta acggttaaca tctgtacgac gtaggtatgc caacaagtta
    30361 cgacggtgac caattttttt catcaatcca cggtaagtag cgtggtcttt tttgtgttgt
    30421 ttgatgtggc tgttcaagtg gttgatttcc caagtaagaa ctgctacttg aacttcaact
    30481 gaacctgtat cgccttcatg acgtgcatat tgagcaatga tttcattttt tttctctttt
    30541 gagattgcca taatatattc tccttttttt gcttaatccg agtcttagga ttggcactcc
    30601 taaaaccaag aaaaagttgg tttgtctttc gaccactcta ttctagcaga ttcataatat
    30661 taggtcaacc gttatcctat tattctaagc tctcacatcc aaaccacctt aagcaacaga
    30721 actagcaagg ccaaatagcc aagaggctgt ttttaaatca gaataaacct gtgcgattgc
    30781 ttgcctaata agataaccag ctaaaagagg taagatggct gatccccgca cttcagctga
    30841 taagcggtaa cctagcatag tcattcattt ctttccaaca aagtgttcac tgataatatt
    30901 aattgctcta gtattaacaa acccaatccc taatccatga acacagctta ttaaccgatg
    30961 cgacctgcct ttatgacata ggtcaagagt tgacacaaaa tgtttgccaa caaaacatta
    31021 cctataccgt caaagagcgc tttgcttcct atacccttga agcgcaagcc aaccaagagg
    31081 ttcatctaaa ccttacatta ttagcaaacc gttttggaac aagcgatcgc catcttaagc
    31141 acgtacttaa gcagcccatt tttcagagga ttatcgaacg catctgcttc aaaacctatc
    31201 gtattgccga tttagacgct ctaactcaat taagacctct gaggtatgca gcccattaac
    31261 ttataatagc aatcactcta accactatct gacttttctt taaaaaagaa atgatttgtg
    31321 atatagtaaa tccagttaaa aaaaagtaaa ggagtagaca tgtctgcaca agataaatta
    31381 attaaaccta gtcatctgat taccatggat gacattattc gtgaagggaa tccaacttta
    31441 agagctgtcg ccaaagaagt gagcttaccc ttgtgtgatg aggatatcct attaggagaa
    31501 aagatgatgc aatttttgaa gcattctcaa gatcctgtaa tggcggaaaa acttggtctt
    31561 agggccggtg ttggtctagc agctcctcag attgatgtgt caaaacgtat catcgctgtg
    31621 ctcgttccta atcttcctga taaagaagga aatcctccta aagaagccta tagctggcaa
    31681 gaagtcctgt ataatcctaa aatcgtttct cattctgttc aagatgcagc cctttctgat
    31741 ggcgaaggtt gtttatctgt cgatcgtgtt gttgaagggt atgtggttcg ccatgctcgt
    31801 gttacagtag actactatga taaagaagga caacagcatc gcatcaaatt aaagggatac
    31861 aacgctattg tggttcaaca tgaaattgac catatcaatg gtgttttgtt ctacgatcgg
    31921 atcaatgcta aaaacccctt tgaaaccaaa gaagagctct tgattttaga ctaacaaaaa
    31981 aaggcccttt agcctttttt tgttagtcta aatagccgct aaaagagcct ctgcctgaga
    32041 tagcaagttt gcttttgtct cttttgaaat ctcaagcctt cctgttcccc aggcatcagg
    32101 attcacagtt gcttttgtaa actctcctgc tactgaagtt cggataaacg gcaatagtgc
    32161 tttaaactga tcaaatactt gatcatgccc gccatttgca actgaagaga ccgtaaccac
    32221 cttaccgcca atagcagatg ggcccgtcgg atcagacaaa tcaagagcac gagacaacca
    32281 gtctagcagg tttttaacag aacctggaat agagaagttg taaactggtg taaaaatcca
    32341 gatagcatcc gctgactgaa cagcttgacg agcgtcaaca actggtaaag gtgcattagc
    32401 ttcgatatct tgattcaaaa caggaacgtc tttccaattt aagtaagata caactgcttg
    32461 atgttccaga gctttttgtg cttgagccgc taattgatgg ttaaaagacc cttcacgaag
    32521 cgagccaaca ataaataaaa tatgtttcat ctctttgccc tcttttttta aagatcgttt
    32581 taaagctttc taaaagtggt atttcattga tacttctttt tgaaatttat cactatgtag
    32641 taattatatc ttctctaaga agagctgtaa agagatttgt ttataattgt ttgaactttt
    32701 tgagaagttc aatcagacaa agttgttctt tttcagtcaa aacagcaaag gcttcttcca
    32761 cccgtgcgac gtgtttaggc aaaacagctt caatcaagcg agtaccctta tctgttaagg
    32821 taaccacata ggctctttta tccgttttgt ctttgcactt gctaatccag ccattgcgtt
    32881 ccatattatt tagtacaaca gtcatattcc ccgaagtcgc taacaaagaa tcaatcaagt
    32941 gattgattcg catacagcct ttagtatata gtacttcaag cacactgaac tgcgtggctg
    33001 ttaaatctgc ctttttaaaa atatcagccc caaaagcatc tagcgttcgc tgagctttac
    33061 gaaacaccac catggctttc aaagcggtgt tcttatctaa atgactcatt tgatttcctc
    33121 gctttatacg gtatgtcaca gtttagtatc agagagatta gaaagtgatc ttgtccctct
    33181 tcttttatga ctttgcatat tactatcatc atgataatct agaaaaagtc atcaaaaaga
    33241 cttaattgat tatcttctgg catatttcct aaaataccca tctcatccat tttctcaacg
    33301 agcgttgacg atgccccgcc tcgtttacgc aattccattt tagagaggaa ttcgccttct
    33361 tgacgagctt taacgatttg cttggccacg ttttcaccca gaccttctag cgctataaat
    33421 ggagggataa gggtatctcc tttgatttgg aattctatag catcactttt gtaaaggtct
    33481 aatttgccaa acttaaagcc gcgttctaac atttcgttga caatctccaa ggttgtaaag
    33541 aggtcatttt ccacattggt ggcttcatta tttttacgtt ttatagtaat atcttccatt
    33601 cttgctttaa cagcatctaa accaccactc atggttttta attcaaaagc cttcgcacga
    33661 atagagaaat aagcacaata atacataatg gggtggtgca ccttgaaata agccacccga
    33721 agggccatca aaacataagc tgccgcatgg gctttaggga acatgtactt gatttttcca
    33781 cacgattcaa tgtaccagtc gggcacattg ttttctcgca tggcatcaat atagccatta
    33841 cgttcttcct cagaaatttt tagccataat cccttacgca cacgctccat aatggtaaag
    33901 gccatttttg gttctaagcc tgcgtgcatg aggtaaacca tgatgtcgtc acgacaaccg
    33961 ataacggttt ttagggttgc aatgccttct ttaatcaaat cttgtgcatt accaagccaa
    34021 acatcggttc catgagatag tccagacaac tgcaaaagct ccgcaaaagt ggtcggatgc
    34081 gtctcattaa ccatgccgcg aacaaagttg gttccaaatt ctggaatgcc tagcatacca
    34141 gtcggtgtcc caatttgttc cggggtaacg cccaaaacct ctgtcccaga aaagagagcc
    34201 ataactcccg gatcatcagc aggaatagta ataggatcaa tgcccgataa atcctgaagt
    34261 ttacgaatca tggtcggatc atcatgccct aggatatcaa gtttcaagac gttttcatca
    34321 atatcatgga agttaaagtg agttgtctgc caagaagccg ttacatcatc ggctggatat
    34381 tgcacggggg taaaatcata aacatccatg taattaggaa taacaacaat ccccccaggg
    34441 tgctgcccag tcgttcgttt cacaccagca gcacctgctg ctagacgatc cacctcagca
    34501 tcacgataga acttgccata gtcgcgttca tagcctttga caaatccata agctgttttt
    34561 tctgctacgg taccaactgt tccagcacga aaggcgtatt cgtcaccaaa aatatctcgg
    34621 acatccaaat gggcactggg ctggtcatca ccagagaagt tcaaatcaat atcgggcacc
    34681 ttatccccat caaacccaag aaaggtctca aagggaatgt cttgcccatc tttttgataa
    34741 ggggtgccac atttcggaca gggtttatta ggcaaatcat agccagatcc aactgaccca
    34801 tctgtgataa attcagaatg ttggcaggac gggcaaacgt agtgaggcgg cataggatta
    34861 acctcagtaa tcccaatcat ggtggcgaca aagctagacc ctacagatcc cctagaacca
    34921 actaggtagc ctcgctcatt tgaccggtta acaagcattt gggaagcgag ataaatcaca
    34981 gcaaaaccgt tccccaagat agaggttaac tctttttcaa tgcgtaaatc aataatatct
    35041 gggagaggat taccataaat ttcaaaggct ttttgatagg ttaattcggc aaccgtctct
    35101 tcggccttat caatatacgg ggtgtaaaga tcgcccttaa ccacttccac ttcctcaata
    35161 cggtccgcaa aatcctgagt attttgcaca actacttgat aagcgaggtc ttttccaaga
    35221 aaggcaaact catccagcat ttcattggtt gttctaaagt gcgctttagg tagaggagca
    35281 ggctgtgccc cttccccacg gccgattgtt ctattaatca tggcaccctg accaagacta
    35341 cgcacaataa tttcacggta aatctcttct tcaggctcta gataatgcac attcccagtg
    35401 gcaagcacag gtttcttagc tcgtttccct acttcaatga ggtcacgaat cacctgctca
    35461 atacctgctt gatctttgat taattcacgg acaaccaatg gctggtaaat ggctggtggc
    35521 atgatttcga taaaatcata atacctagcc aaatcaaccg ctgcatcaat tcctttagtc
    35581 agaacggcat caaaaacctc gccgtcagaa caagctgtac caagtaacaa accctctctg
    35641 tgagcatcta agacggttct tggaatacgc ggcacccctt caaaatattt gatattggaa
    35701 aggctgacca acttaaacat atttttaaga ccaacctgat tttgcacata gatagtcgca
    35761 tgcttaatcc gcgctttttt gtaagaatcc tcagccacca aatctgtatt gagttgcaaa
    35821 agatttttga tgccatgctt ttctctggca tcttttagaa aaataaacaa aagacgtcct
    35881 gtggcttccg cgtcgtaatt ggccatatga tggtggtcta gactcacttg gaaacgcttg
    35941 gtgagcggtc ccaaaccgtg acgcttgtac tcaggataca agtttctagc aaattctaag
    36001 gtatcaatca caggctgtgt gattttgggc aagtcgtggc gttcataatt ggcgttcata
    36061 aagcccacgt caaaactggc gttgtgggca accaagatac tatctttgca aaagtcctga
    36121 aaagctttta ggacagtaac caatggcttg gcgccctgca aatgcttatc ggtaattcct
    36181 gtcaattcgg tggtaaaggc tgaaagagga tgcccaggat caatgaattc atcaaactgc
    36241 tctacaatat ttcctttaaa cattttggaa gccgcaatct gaatcaggtc attattcata
    36301 gcagatagac ctgtggtttc cacgtcaaag accacatagg tagcttcgtg caaatccata
    36361 tcaacaggtt cataagaaat aggcaccttg tcctcaacaa tattggcttc taggccaaaa
    36421 atagccttaa tcccagcttt gcgagcccta tggtagccat gaggaaaact ttgcacatta
    36481 gcatggtcgg tgatagcaat cgccttgtgt ccccacttgg ctgccgtatc aatcaagctt
    36541 tctactgtcg gtaaggcatc catggtagac atattggtgt gggcatgaag ttcgacccgc
    36601 ttttgccctt ctggcatcag gtctttgcgc tcatgacgga caatttcttt gacctgctgg
    36661 acattcatgg tgagactctt cgtaaaagga ttggtctcaa tattcccttg tacccgtaac
    36721 caagctccct tagcaatcat atcaaattta cggagctcct catcgtcttt agcccatttt
    36781 tggagagcaa acgaggaggt atagtctgtc attttaaagt tgatgatatg gcgacctgtc
    36841 ctagtcgttt tacgctccac gtcaaaaacc ataccctcaa agacaatccg gttttcttcg
    36901 gtctcaatct caatcattgg tgtgatggtt gctttttcaa accctgcctg acgcttagct
    36961 gctcgttcct tgtagtcaaa cttaggagca ggtgtggctt cctcaactgg tggcatcatg
    37021 gcttcaagag atttttgggc ttccaaatta tcctgcacag cctttttcac aagagcctga
    37081 cgactggaaa caaaattctt ggtcaaatgc tcagtcattt cctgatctga caccatatct
    37141 atggtcaagg tgccaaagcc aaaggcttct aattgcttga ccagattagg cagatgattg
    37201 tttctaaaat gatcgttatt cacaaaacct ggcgctgcaa taatgagttt gtcatcctca
    37261 taagtcactt tgagctttga gaaagaagat ttaaaactag cactattaca cggtgcatgc
    37321 tcaaaagctt cttggtaata agcttgaagc agatcatctg aataatccac ctgagcagct
    37381 tggatgtcaa aggttacctt aatgtcagcc gcctcaaaag ttcttatcaa acgatcatgc
    37441 aattcacgat aagttgcaat cggtaaaacc gctgcaaagg caaaatgaaa ttcccacaag
    37501 cgtgacaccg aatgtacctt tacctcgata atatcagcag atgaaaaggc acttgaacgt
    37561 ctcatgtcaa gtggcatttc tatctggtcc atcaatttag cgaataaatc tgacataatt
    37621 ttctcctgat tttactaggc tttattttat cacaattcaa gatgattttc gagttttaga
    37681 tggaaagaaa agcagggctt tcttctgacg ttctttggct aatttattcc aagtgatagc
    37741 tcagttgagg tcattttttt tgccaatctt ttatcgccaa gcgcttttgg taaagcaaaa
    37801 gccactctgt atcagacaag ttcacagcaa aaagaggcca ctctaaacag gcagcctctt
    37861 catttctttt ttagtgttct tttgttaaaa tttcaagggt ttcgatgagg ttttctgcat
    37921 taacttcaat gctgtcacct gttgccttga ttttaatttc cacgatacct tcagcggctt
    37981 ttttaccaac agtgacacga attggcaaac caatcaaatc gctatcagag aatttcgaac
    38041 cgacgcgttc attacggtca tctgtcaaga catcataccc tttagccatc aagtcagctt
    38101 ctaacttcgc cgtcaagtct tgggccactt gatctttgac attaactgta atcaaatgca
    38161 cgtcaaatgg ggctaattct ttagggaagt taatacccca agcataacgg taatcgcctt
    38221 ttggtgtctt gttcacaaag agacgggcat gctgttcaat gacagcagac aaaatgcggc
    38281 taaccccgat accataacaa cccatcacaa ttggaactgt tctgccattt tcatcaagaa
    38341 tcgttgctcc catgctgtct gaataacgag tgcccaactt gaagatatga ccgacttcga
    38401 taccacgcgc aaactggaga acaccatgac cgtccggaga catttcccct tctttgactt
    38461 cacgaatatc tacatattca gcctggaagt cacgtcctgg attgactcct gtcatatgga
    38521 aaccatcctt gttagctcct gcaacggcat tggtaaggtt ttgcactttg cggtcagcca
    38581 caatacgact accttgtgcc aagttgacag gcccaagtga gccaaaacct gcaccaaaga
    38641 aagcacgggc ttcttcttca ctagctggct ctaaaaaatc agcagctaga tagtttttta
    38701 atttaacggt attgatatgg tcatttccaa ctagcaaagc aacaacaggt tcattatctg
    38761 ccacaaaaag caaggttttg atggtttgtg tttcatctac tgaaagaaaa gcagccactt
    38821 catcaatcgt tttgcaatgt ggtgtctcaa cttctgccaa ggcatcttca gcagctactt
    38881 ttgaggacgg tttgtattcg ttagttgcca tctcaaggtt ggcagcgtag cttgattctg
    38941 ttgaataagc aatagtatct tcacctgaaa tcatccaagc agccaattct gccttaatat
    39001 cttctaagac ctcttttgga atatcatcca ttgacgcaat agacttgtca agaaccaccc
    39061 agcgatcaag atccgtacga gctggtgtaa tggccataaa ttcttgggaa tctttccccc
    39121 ccatggcacc gccatctcca ataatccctt tgaaatctaa accagctctg gtaaaaatag
    39181 cttcgtaagc ttgacgataa tcttcgtagg tcacatctaa atcttcatag ttgtgatgga
    39241 aactatagcc gtctttcata ataaactcac gggtacgaag caagccatta cgcggacgtt
    39301 tttcatcacg atacttagac tgaatttgat aaaggtttaa gggcaattgc ttgtaagatt
    39361 tgaccgcatc acgcaccaaa gtcgtaaagg tttcttcgtg agttggaccc aagataaagt
    39421 ctgagttatc acggttttta agcttataga ggtcctctcc ataggtctca taacggcctg
    39481 attcacgcca gagatcagct gtcaaaagag ctggcgccaa catttcaaca gcaccgatct
    39541 tttcaaactc ttcacgcatg atggtcttga atttctcaat ggtacgattt gccagtggta
    39601 aataagcata gataccagca gaaacttggc gcacataacc ggcacgcacc ataagcgcgt
    39661 ggctgataac ctgggcatca cttggcattt cgcgcaaggt tgggataagc agtttacttt
    39721 gtttcataga ttattccgtt ttaatacatc cccttatcct caaacccttc tggaaacatc
    39781 aagtaagagt gaagcgggat tattcaataa tttgaatgtg tattcctttc attttgagta
    39841 agacctcaac ccttgcaaat cttagggttg aggtcttttt cgatctttaa catgataagg
    39901 tcagcttaag atgacctatc ttgattagaa aaagacgcgc atgatatcat tccatgtcac
    39961 agcaatcatc aatacgacca tgatagcaac cccagctagg gtgatatagg cctctgtttc
    40021 ttgcttgata ggcttgcgac gaatggcttc aatgatattc atcaagattt ttcccccatc
    40081 aagtgcagga atcggaatca ggttaaagat ccctaaattg atcgaaagca ttgccataag
    40141 agataagact gactctaagc cgttttgagc agcctgattg gacatgtcat acatggcaac
    40201 aggtccacct aatttattga gactaaagcc agtgatcaat cctttcaaag cattcaaaat
    40261 agtaaacgcc ctactccaag ctaattctag accgcctaag agcttatcct taaatcctgt
    40321 tttcagactc gccttaactc ctatcgtgta tgtctttgca tgcttttgtg gtttcacagc
    40381 caccgttttt aagcgctgat gtgacttgta ggtgacctta atggtctgtg acgggcctag
    40441 atcccgtgtt gcaaggtcta cagcctcagt gagatcattc cagctagtca ccttgtaacc
    40501 attaattgcg acaatttggt cattatctcg aagaccagcc ttagctgctg ctccattttc
    40561 ttgaacacgg acatgattgc tactaaaatc tggcatccca ccttgtaaaa agaccaagag
    40621 gataaaaacc acaatcccta aaataaaatt attcatggga cctgcaaaat tggtgattaa
    40681 acgtccgcca atactagcat tttgatattg aacatcaagc ggagcaattc ttatctcagt
    40741 accgtcttct tcaacaatag tagcatcgtg agcgacctta tatgtcttgg tttcttctaa
    40801 aactaagcca gtaatactca gctgatcttc taagtcatag cctgtaacat gcattgggag
    40861 actcgttggg tctaacttac tttgagacaa gttgatgcgc ttaacaaaac cttgctcatt
    40921 aagggttaaa cttgttggag tacctgtttt gatctcagtt ttgtcatcac cccaaccagc
    40981 cattcgcaca taaccgccca agggtaacat cctcaaggta taaagagttc ctccttggtc
    41041 aacatgagaa aaaattttag ggcccattcc aatggcaaat tctcttacta gaatgcctga
    41101 ttttttagca aaatagaaat gtccaaattc atggacaatc actaaaatac caaaaataat
    41161 aataaaggtt attattccta acatagattt cctttcagtc tattgctttt ttgagttttg
    41221 tcgcgttgtt gcgactccaa acattacctc ttaagattaa aataaaccaa agagatgcat
    41281 gatgggaaaa acaaaaatca tggaatcaaa gcggtctaaa ataccaccat gtcccgggat
    41341 aagcttacct gaatctttga caccaaagtg acgtttgaga gcactttcaa ccaaatcacc
    41401 aaattgggca aaaatggaaa aaagagcgac caaaaccaac atggtcaaaa agtgatgtgg
    41461 cgcataaaca gacctatcaa tcaccataaa gataaaagac acaaggactg cacaagcgat
    41521 ccctcctaaa ctaccttcaa tggttttgtt tggagaaact gtaggcaata gtttgcgtct
    41581 accaaactga cgcccaatca gatatgctcc aatatcagtg gcccaaacga taaataaggc
    41641 caaaaagacc ttgtcaattc ctgacaggcg agcattgatc aaatgttgaa aaccaatccc
    41701 aacataaaaa ctagttgcaa tcggaaaggc cgcatcatca aatgaataag ctctgctatt
    41761 taaaacagta cctgccaaaa tgaaaaaaac cattaagctg taaaaagcaa cattcgcatc
    41821 aattggtaaa aaagtgaggt aatggtccat cggaactgcc aatacaaagg cggctaacat
    41881 ggcaaaaaca ccttcaaaag aaaagacttc taatcttttc attttcagta attctgatac
    41941 cccaatcatg gccaaaacgc ctacaaataa ttggaatggt aggtttccta ttatgagaaa
    42001 aggtaggaaa atagctactg ctactccccc ccaaacaaca cgttctttca taactatctc
    42061 cttttagacc ttgccaaaac gacgttggcg gcggttataa tccgcaatgg cctttagtag
    42121 ctctgccttt ttaaaatcag gccacaagac tggtgtgaaa taaaattcac tgtaagctga
    42181 ttgccaaggc aagaaattgc tcaaacgcag ctcaccactg gtgcgaataa tcaaatcggg
    42241 gtctcggtag agatatggca gatggtctgt catcaagtaa ttagcaatca aatcctccgt
    42301 aatatctcct ggatttaatt tggcatctaa gacatcttga gcaataaagc gaacagcact
    42361 ggtaatctca gcacgtcctc cataattgag agcaaaattc aaaattaaac ccgtattacg
    42421 ttttgttttg tcgatggctg catttagcgc tgccaaggta tcttcaggta aacgactagt
    42481 ctctccaatc atttgaatct ttacattgtt ctcatgaagc acaggcacat atttgtcaaa
    42541 gaaggttact ggtaaattca tgataaaaga cacctcatct tggggtctgg accagttttc
    42601 tgtcgaaaag gcatagactg tcagaacttt aacccccaac tcagatgcag taatcgttac
    42661 ttcttgtaaa gcatccatcc cagctttatg cccaaacact ctaggtttta gtcttttttt
    42721 ggcccaacgt ccattaccat ccatgataat tccaatatgc tttgggatac tccccaaaac
    42781 tttttttgtt gatttcgctt ttaatccaaa catgtttttt ccttattgat aagcatactt
    42841 atctcatatt ttatcatatt tcacgccttt tggcttgttt tttatcaatt agatcttatc
    42901 ttcacaaaat gttcacctat cctctgatag atgtgtcagc ttttcatgaa cctgttagca
    42961 tcagaataac tgtttcaatc cagggatcaa aacaaaaaag tttggcatat ttcatccaaa
    43021 ctttccccgc cttaatggct ttcaatggca ctgtcagtgt cagtgctatc tactgtctca
    43081 acagcaggct cattaacaac actggtttct tctgtttcaa ccagtgtcgt ttctgtagta
    43141 gcttttgtta caatacgctt aatagctaat agctcaaatg tcaaaaagac gccatccaca
    43201 tctaacacaa tctttttagc tgttgtatcg acttcgtcaa caatcgcaaa catgccacca
    43261 atcgttacga cttcgtctcc tttttcaata gcgtttaact gattttggcg ttcttgcgct
    43321 tgtttttttt gttgacgttg cataaaccaa atcaatccaa gcatcactac aaacattaaa
    43381 attgttggaa atcccataat gtctcctttt tattctataa aagtcatgtc ttactatatc
    43441 aaaaatcaag cggtatagca agactagacg ttacctgatg tcttctttaa acgagacgct
    43501 aagcgcagtg ctttactcac gagtcaaaaa agctaagatg tcatctggtg tcaaacttga
    43561 atcacataca gccctttggt gctgatcgta actaaccagc aaagctggaa ctgtcactaa
    43621 ttggtagttc tcacgaaagg cagcaagctc agcagcatca gcagcgtttt cgctatccac
    43681 aaaatagact tctttttgat tatctgttgc tacttgtgcc aacttgggag caaagcggcg
    43741 acaataagga cagctcgaac gtcctaaaaa gacaatcatg tctttgccac tagcgatagc
    43801 tgatgtgact tctgcaacac tcgacggtat aaaattcgca acgatttctt caaatgtcat
    43861 ggatgtctcc ttctcttttg gtctcatgat acactaaagt agcaattttc tcaatcacaa
    43921 ggtcttttca cagctcagag cttttatagc cgtcaaaaag aatccgcaaa cagcaatctt
    43981 tttgtctcta ttaacaccac cctaatcttt ttggcgcttc atcaacaggc taatagccaa
    44041 taaaagcaga gctattccag ctgctaataa gccttttgag gaggcttcac ccgtttttgg
    44101 gagcttttgg tttgttttag ctctttttgg tctagtcatt aatgatttgt ctaggtcttt
    44161 tgagccatct ggtgttttgg tttgatgatt gtctgtctga ctcttttgct gagagggatt
    44221 agccgttttt gaggatactt tgaggaccag ggcagttagg ccttcaatag tcaagccttc
    44281 tttggtaaac tggactccct taggcttagc aatggcagta acaccagctt gctcagcatc
    44341 aacaagcact tgggctccta gcaaatagcg gtaggcttga ggtaaaacta ccttgcgggt
    44401 cttgttgtct gcattgacaa agacagcata gcgatctcca tttgatgcca ctgtttggta
    44461 acccatgatg aggtcctctt gttgaatacc atcttgtcct gcttgggtga tcaaggtcac
    44521 atcccgatct acctcagctt tggttgcttt tgtaaaggca tctgttgagc gacgcaacgc
    44581 aattagtccc tgtgtatagg cttttgtttg gttgctaatc gggtgagcta tggaatctgt
    44641 tgcctttgcc cagtcaaaat gattgaccgc atcagacgaa tcataagaat cgtggatgaa
    44701 gtaagggtat tgcgctacag catcaatcag agtcgcctta tttggcacct tgtcatcaga
    44761 cgcctttgtc ttgtagtcgg gatttagaag ctgcttggtt cgtccatatt cctgaccaga
    44821 atggataaag gcagtccctt gagcagttaa aatcatggta tttcctagac gaatacgctt
    44881 gtgaatctct tcttcagcca ctttaggatc cttattgatg gatttggcaa tgacatcatg
    44941 taaggtcagg ttgtcatggg ctgcaatata ctgcactaca tctcctgggg catctgcttc
    45001 aaagttacca ggctgtgctt tgatcgtttt gaataaacct tctagatttt ttgcgccacc
    45061 agtaataaag gctgctgtgc cttcatttgg aaaacctgac ttgagggtat ttctgatatc
    45121 atcagagaaa acaccgaccg tattggttgc tttcatccaa tcttgatctg ccgcaatttc
    45181 ttttttcccc tcatcacctt ggtaggtacg ccagccttcg ccaatcataa tggtatttgg
    45241 attaatggct ttggctgcct taaaggcttg ctcaatagct gccgcatcat ggtcacccat
    45301 catgtcgaaa cgaaaaccat ctaccttgaa ttcacgagtc agataagtaa tcgaatccac
    45361 caagatacga cgactcatgg catgtgtcgt tcctagacga cctccgccaa aactctctct
    45421 agctgtacca tcagcattca taaaatgata gtagttgggt tccaaatctt caaagagata
    45481 ggttctagcc gtgtggttat aaaccacatc aaaaataaca cccataccac gtttgtgaat
    45541 ctcattgaca aggtttttaa gctctgcgat acgtaaagca gggtcattag gatttgccga
    45601 atacatgcca gaaagggcaa agtagtgttg tgggtcataa ccccagttgt aattattgtc
    45661 tgaagacgtg taggctgttg agcggctctt gtccagctca ttggcataaa aataactcaa
    45721 aaccggtagc aattgaacgt gggtaacccc caagtctttg agatagtcta gctgttcaac
    45781 gaaagctgaa aaagtcccaa aagggtgtgt taacttgcct tctagagcct tatctgacgt
    45841 aaaatctcgc acatgtgctt catagataat agcgtcttca cgctttttaa agttgttaat
    45901 tttggcaaaa tcaaggcctg ttggtcctag tttgcttgga tcaataaagg cagcttttgc
    45961 tgttttgatg tcatcagtag cagtcgcatc attccaggca gcgagagatt tggcgtaagg
    46021 atccaaaacc atgacttttt cctgaccgcg cgtgatttca taaaggtaat agtagcctgt
    46081 gtaatcacta atgcccttga cactgtcaga agttagatga gctctccaaa cacccttgtc
    46141 cgacttggtc aaatcagctt gaccaaccac ccttgtctga tcttgtttat cataaacgac
    46201 aaccttaaca gtatcagcac ttggagacca tagcgctaaa tcaacagaac catccttagc
    46261 tagggtagct ccaagttcac catcgtaagc atagagttta tcttttaatt gccaggattg
    46321 gcgagcgact tggctaactt ctccaaatgt aaccgtgtag actgcacctt gcgccttaaa
    46381 atcacccttt aatgtcatta cagacttatc cctgtcaagt gtcaactcat caattgcaac
    46441 agttttccct gctttgtcag tgatcttgat gttttgtttc accgcatctt catcaagccc
    46501 atctaaggtc gtaaaaatgg ctttaatctc atttggcgtg gtttgttcag ctcctttgag
    46561 actaacctga tcaatataat aaggattgtt gtaaactttt gggtcagtgt ctttgacaaa
    46621 aacctgagta tgattgtcta actctttaaa tagataatct tttggttgca ctttaatagc
    46681 atctcctgtc ttacttttat caaggattaa aaatccgatt tcgttagctc cttcttttaa
    46741 ggggacatca acataagctc cataatgccc tttatgtgac aagtcaagtc catttggcca
    46801 gtcggtcgtt ggggttttga catctttaaa ggtccagaca gctaagttat cgtagtgtcc
    46861 cgattgattg tggtagttga ttcgaaggta accttttttc aaaggtcgat aagcgtgcgc
    46921 atggtaattc tcgtctatcc aaacttcatt catttttggc gtgagaagcg agatgtgctg
    46981 gtcctttgaa agattctctc cagctttatt attaatgaga taagacactt gctggcggtg
    47041 tttagctgct agtggcacat ctagataata gccatagtca tcttttttcg cttttgtcat
    47101 ggtgatagca ccatttggcc aatcctttga aggttgatcc acatctcccc acacccaaag
    47161 tcccaagctt cctagcgact caccagctgg caatgtttta aaatgcatac gcaaatgatg
    47221 ctcagcaata ctagcaggat tagctgacga gctgtctaaa actggttttg cctccttgct
    47281 agacgattga agaccatcac cagatttagc attgccatct ccttgttgag cttcatcgcg
    47341 ggctagtcca acaatggttt tagcagcaac ttgatgtgtt aagatactag gggtgcaccc
    47401 taacacgaca gtcccagttg cagcgattac aaaacctatc ccccactttt ttaacagata
    47461 ttgatagcgc tttgatcctt ggttgacttt ctttttcata agacctccat ttagtataac
    47521 attcaaacaa gactatctta tcacattgcg caagcgcttg caagacatgc cgcacttcaa
    47581 cttagaacac agctcaaaca atgactatca ccccttaata ggatctcaaa aattaaacag
    47641 ccaaaacgag tttccactcg cttggctgtt gggtaaactc aaatcacata cagctgctag
    47701 gccttcagtt tgagacaaaa ggcatcccaa ggttgtaagt gcttggtctc taataccgtg
    47761 tccacatctg tattggcgat gatcacttgt gcacctgcta agtctgtggc aaagacttgc
    47821 tcctcatcag acacattgac aacaatcaca tacgtctctt ctccaagctg acgctgataa
    47881 gcaaacactt tatcagctgt tggcaagagg tgataatccg cttcaactag ccagtcttgc
    47941 tccttacgca aggcaatcaa tttttggtag gtgtaaaaaa tagagtctgg atcagcaagg
    48001 gcatcggcca cattgatgtc ttggtagttg gggttgaccg gcaaccaagt ctcttttgct
    48061 tcagaaaagc cagcatgtgt gtccttagac cactgcatcg gcgttctagc attgtctcgt
    48121 cctaccttac ggatgctatc catcacacgc gcagctgaca ctccatttcc catagcttcc
    48181 ttagcatagt taagggactc aatatcatta acctcggtta agtctttaaa aggataattg
    48241 gtcatgccaa tctcttctcc ttggtaaatg taaggggttc ctcgcatcaa atgcagtaaa
    48301 atagctaaag ccttggctga tttttctcgg taagtgctgt cattgcccca aatggataag
    48361 acccgtggca agtcatggtt attccaaaaa agcgaattcc agccttctcc taactttaat
    48421 tctgtctgcc acttgctaaa aatagctttc agagcaggca cgtctaattc tttggcataa
    48481 tcccacttgg gagcgtcagg tttatgttga agacccacat gctcaaattg gaagaccatg
    48541 gataactctt tgttttcagg gcgagaatac tggcgagcaa tttcaggcgt tgctccccaa
    48601 gtctcaccga ctgtcatcac gtcatggttg ccaaaggttg cttgattcat ttctttgagg
    48661 taatcgtgta agcgcggccc gttacccgtg atctccaagt caggaacctt cccaatcagg
    48721 tcaatcacat ccatacgaaa accaccgatg cctttggcaa tccagaaatt catcatatcg
    48781 taaatttttt ggcgcagctg agcattttcc cagttcaaat caggctgttt cttgctaaac
    48841 aaatgcaggt aatattgtcc tgatgcctca tccaattccc aagcagatcc tgaaaaaata
    48901 gacatgaggt tgtttggctc gtcacgccaa atatagtaat cacgctcagg actattggga
    48961 ttttctctag cttcaacaaa ccaagcatgc tcatcagacg tatggttgac caccaagtcc
    49021 atgataatct taatgcctcg ctcattagct gctgctaaga gctcatccat atctgccatg
    49081 tctccaaaaa catcagcaat cgcttcatag tcagagatgt cataaccatt gtcatccatt
    49141 ggactttggt aaacaggaga taaccaaatg gctgtaatgc caagtttttg caagtagtcc
    49201 agttgactgg taatgccttt taaatcacca ataccattgc cgctggtgtc tttaaaggac
    49261 cttgggtaaa tctgataaat cgtagcttta tgccaccagt gtttcttcat tattcttctc
    49321 ctattaatca ttcattcatc ttttatttta acgttttttc tctttttgtg caatcgtttg
    49381 cgcaaataac atgataaaaa ggctggaacc caaccttttt atgaatatcg cttatacctt
    49441 aacgaatagc ttgttcggta tctctgtcaa agaaatgccc cttagccaca ttaaaggtca
    49501 agctaacttg ctcccctgga ctatggaaat cacgcgcatc tacacgagaa gcaaactcag
    49561 tttgtccaag cttgacatag agcatcgtct cagagcccag taactcagaa accaaaactt
    49621 ctgctgtgac agttgcactt ggataagtat catgcacgat ttgtctacta gaaatgtctt
    49681 ctggacgaat accaaaagtg actttttccc ccttgtaacc agcagcttca agcatttttg
    49741 cttgtccttc tggaatagca atgtcaagac catcttcact cacaatgcgg ccatctttaa
    49801 cttccacttc aaaaaagttc atggcagggc ttccgataaa accggcaacg aatttattag
    49861 ctggaaggtt gtacaattct tgtggcgagc cgacttgctc aattttacca atcgttccat
    49921 taccttgagg gtttttagtg gcactcatga taacgatacg gtctgccaaa gtcatggctt
    49981 cggtttggtc atgggtaacg taaatagttg ttgagccgat acgacggtga attttagcaa
    50041 tttcagcacg catagacaca cgaagcttcg catccaagtt tgacaaaggc tcatccatca
    50101 agaatacctt agcatcacgg acaatagcac gccccatggc aacacgctga cgttgaccac
    50161 cagacaggtc agccggttta cgctctaaaa attcggtcaa accaagaatc tgcgcagctt
    50221 ccttgacacg acggtcaata tcatcttttt tgtacttacg taatttcaaa ccaaaggcca
    50281 tgttatcata cacagtcatg tgtgggtaaa gggcgtagtt ttgaaagacc atggcaatat
    50341 cacggtcttt aggagacttg tcattcacca cttcgccacc gatttttaac tctccttcag
    50401 aaatgtcctc aagacctgca atcatacgaa gagtagtcga tttaccacat cctgaaggtc
    50461 caacaaagac gataaattct ttgtctttaa tgtctaagtc aaaatcttca acggcataat
    50521 gagtagtatt tgggtatttt ttatagatgt gatttagatt taattcaacc atgtgtaact
    50581 cctatttgaa cagcaaacgt tctagctgac tgcaaagcta gaaaccactg atatctttta
    50641 tatgatgctt ttattataac aaaaatagcg ctttcaaaac agagacaaag cgaccaaact
    50701 tctttgggca acttgcacaa tagcagggct agtcaagtcg taaagaccca taaaacaaga
    50761 aaaccatgta aacacaggcc ggtcacagga gccaaaacaa gctgaacgat ctatcattct
    50821 ccctatcagc tacagtccag gcagcaaaaa agaaagccct gtgcctttcc taatatttca
    50881 acaaaaagag atgagcaaag gctaaatcat ccaattgctt caagtggagt cctgattgct
    50941 gagcaaattt atcaagtttg tattgcaagg agttacggtg aatatacaag cgctgcgctg
    51001 tctgcaccag attgccgtgt tctgaccata gcgcgtgaac cacatcggcc atatcacttt
    51061 gaggacttag gaattggtga aactgacgcg tcaatgccaa aaaagtgtgg tgcgacagca
    51121 aagaccacag catcagtcct gaaaatgtta ataattttct gcctgattgt tgccttaaat
    51181 aggccgttaa cagctgacat tcctcctcaa aacactctct caatgtaccc gcagctacct
    51241 gataccaggc atttccaaca aacatggtta aggccaaacc aaaatcactt tctagcgttg
    51301 gcaggagatc ttcaagccag cgcaagacct ttattgagat tgcttgtcgg cataaaaatg
    51361 ccgtttgggt tgcactgata ggcaaaatga cttcaagccc tgcaatcatt tgttggagca
    51421 actcaactaa gtcatctggt aaagcctgct gatgattaag gtaaatgaac tgagaagtct
    51481 catacagctg agggggattg ccctgatgat caagcaaata ccgctgccaa ggtgacccta
    51541 gcggctgcaa gacctcacac tgacccagcc ccacctcaag taataagcgc tctttttcgg
    51601 ataaacatga tttgggaaaa tgcacatatt ggtccccttc tttgatactc atccaatctt
    51661 tatctcctaa cggatgaggg cctacttgca tctctggaaa atagtctttt agctccatag
    51721 ccattccttt catgacggtc tttaaaccat tataacacat gactctttat cacacagttc
    51781 ggtttgttgt cagcacgatt ttgtattttc tgccttttta atcattaaag ctaaataatg
    51841 gttattcatt tttagcaaga acattcaatc aaatggctat ttatcggaag attaatttaa
    51901 tttattggaa gattaattta tg
//
LOCUS       DAUGJR010000009        50927 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUGJR010000009 DAUGJR010000000
VERSION     DAUGJR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50927
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.009"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            200..937
                     /locus_tag="VH800_000509"
     CDS             200..937
                     /locus_tag="VH800_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEQ8361598.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYETPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            976..1476
                     /locus_tag="VH800_000510"
     CDS             976..1476
                     /locus_tag="VH800_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8361599.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            1491..2180
                     /locus_tag="VH800_000511"
     CDS             1491..2180
                     /locus_tag="VH800_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEQ8361600.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASSAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            2358..2600
                     /locus_tag="VH800_000512"
     CDS             2358..2600
                     /locus_tag="VH800_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEQ8361601.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            2778..3572
                     /gene="racE"
                     /locus_tag="VH800_000513"
     CDS             2778..3572
                     /gene="racE"
                     /locus_tag="VH800_000513"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEQ8361602.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            3569..4555
                     /locus_tag="VH800_000514"
     CDS             3569..4555
                     /locus_tag="VH800_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEQ8361603.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRHQSPLSLITFIIDMINQETQREIKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEADWPGYIATQPKG
                     ENGFGYDPVFIVGETGHHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            4534..5055
                     /locus_tag="VH800_000515"
     CDS             4534..5055
                     /locus_tag="VH800_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEQ8361604.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVV
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            5052..5513
                     /locus_tag="VH800_000516"
     CDS             5052..5513
                     /locus_tag="VH800_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8361605.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            5510..6256
                     /gene="xerD"
                     /locus_tag="VH800_000517"
     CDS             5510..6256
                     /gene="xerD"
                     /locus_tag="VH800_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEQ8361606.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLIGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPMTLEKYYKS"
     gene            6256..6957
                     /locus_tag="VH800_000518"
     CDS             6256..6957
                     /locus_tag="VH800_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEQ8361607.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEDLEQDLLEKIEEYSRFKAVSQ
                     ALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKNNHTVI
                     ERDDYKIEDMMASIKQRLEKENVIRLSAIFEECQTLNEVISIFLASLELIKLHVVFVE
                     QLSNFGAIILRKEKK"
     gene            6954..7505
                     /locus_tag="VH800_000519"
     CDS             6954..7505
                     /locus_tag="VH800_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEQ8361608.1"
                     /translation="MTYLSQIEALLFIAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            7628..8350
                     /locus_tag="VH800_000520"
     CDS             7628..8350
                     /locus_tag="VH800_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8361609.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKSRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            8347..8610
                     /gene="yidD"
                     /locus_tag="VH800_000521"
     CDS             8347..8610
                     /gene="yidD"
                     /locus_tag="VH800_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEQ8361610.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            8788..9336
                     /locus_tag="VH800_000522"
     CDS             8788..9336
                     /locus_tag="VH800_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEQ8361611.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      9445..9568
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            9647..10210
                     /locus_tag="VH800_000523"
     CDS             9647..10210
                     /locus_tag="VH800_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8361612.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            10212..10865
                     /locus_tag="VH800_000524"
     CDS             10212..10865
                     /locus_tag="VH800_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8361613.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILLIGLSRIYLGVHYPSDILAGFVLGFGILHFIYPFYKQKRFEWRFLLKQD"
     gene            11158..12078
                     /locus_tag="VH800_000525"
     CDS             11158..12078
                     /locus_tag="VH800_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEQ8361614.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            12117..12671
                     /locus_tag="VH800_000526"
     CDS             12117..12671
                     /locus_tag="VH800_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8361615.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADF"
     gene            12804..14138
                     /locus_tag="VH800_000527"
     CDS             12804..14138
                     /locus_tag="VH800_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEQ8361616.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            14216..15007
                     /gene="pflA"
                     /locus_tag="VH800_000528"
     CDS             14216..15007
                     /gene="pflA"
                     /locus_tag="VH800_000528"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEQ8361617.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            15138..16073
                     /locus_tag="VH800_000529"
     CDS             15138..16073
                     /locus_tag="VH800_000529"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEQ8361618.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            16149..16802
                     /locus_tag="VH800_000530"
     CDS             16149..16802
                     /locus_tag="VH800_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEQ8361619.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNRVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDFVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(16847..17884)
                     /locus_tag="VH800_000531"
     CDS             complement(16847..17884)
                     /locus_tag="VH800_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8361620.1"
                     /translation="MLFMVNKKRRPLLKSQRHLLRLYTSLILLLVSLMGLALSLGESH
                     LSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(17845..18897)
                     /locus_tag="VH800_000532"
     CDS             complement(17845..18897)
                     /locus_tag="VH800_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8361621.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(18887..19819)
                     /locus_tag="VH800_000533"
     CDS             complement(18887..19819)
                     /locus_tag="VH800_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8361622.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAVTTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEDKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEIIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(19845..20627)
                     /locus_tag="VH800_000534"
     CDS             complement(19845..20627)
                     /locus_tag="VH800_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361623.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(20873..22318)
                     /locus_tag="VH800_000535"
     CDS             complement(20873..22318)
                     /locus_tag="VH800_000535"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEQ8361624.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            22406..24040
                     /locus_tag="VH800_000536"
     CDS             22406..24040
                     /locus_tag="VH800_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEQ8361625.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEERAIHLFVAVLFQTLLLALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            24208..24837
                     /gene="upp"
                     /locus_tag="VH800_000537"
     CDS             24208..24837
                     /gene="upp"
                     /locus_tag="VH800_000537"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEQ8361626.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            25061..25651
                     /locus_tag="VH800_000538"
     CDS             25061..25651
                     /locus_tag="VH800_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEQ8361627.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            26143..26418
                     /locus_tag="VH800_000539"
     CDS             26143..26418
                     /locus_tag="VH800_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEQ8361628.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            26667..27302
                     /locus_tag="VH800_000540"
     CDS             26667..27302
                     /locus_tag="VH800_000540"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEQ8361629.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQDILTTREPGG
                     VAISEHIRELILDINHTAMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            27320..28195
                     /locus_tag="VH800_000541"
     CDS             27320..28195
                     /locus_tag="VH800_000541"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEQ8361630.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHINAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            28214..28453
                     /locus_tag="VH800_000542"
     CDS             28214..28453
                     /locus_tag="VH800_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
                     /protein_id="HEQ8361631.1"
                     /translation="MGKRSLSKDLPVATKVAAHKGKKAFEENTAFATDLMKEVSRLIT
                     QNQLEMTFVNSVFLLDQHVVLIPFSAEEHMDFYNC"
     gene            28858..29181
                     /gene="yabA"
                     /locus_tag="VH800_000543"
     CDS             28858..29181
                     /gene="yabA"
                     /locus_tag="VH800_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEQ8361632.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            29186..30049
                     /gene="rsmI"
                     /locus_tag="VH800_000544"
     CDS             29186..30049
                     /gene="rsmI"
                     /locus_tag="VH800_000544"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEQ8361633.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQADSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            30076..30468
                     /locus_tag="VH800_000545"
     CDS             30076..30468
                     /locus_tag="VH800_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361634.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(30515..31144)
                     /locus_tag="VH800_000546"
     CDS             complement(30515..31144)
                     /locus_tag="VH800_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEQ8361635.1"
                     /translation="MIKEFCAENLTLLPTLDAGQISRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDRIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGITAENCQSLSQLTGTAIVHGTKII"
     gene            31443..31799
                     /locus_tag="VH800_000547"
     CDS             31443..31799
                     /locus_tag="VH800_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEQ8361636.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGN
                     VLQVGYRKPYQELDLG"
     gene            complement(31873..32700)
                     /gene="xth"
                     /locus_tag="VH800_000548"
     CDS             complement(31873..32700)
                     /gene="xth"
                     /locus_tag="VH800_000548"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEQ8361637.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPNSNRRSPGFTDEERQGFTNLLARGFTDTFRHVHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            32934..34115
                     /gene="lctO"
                     /locus_tag="VH800_000549"
     CDS             32934..34115
                     /gene="lctO"
                     /locus_tag="VH800_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEQ8361638.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDYLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            34378..39321
                     /gene="scpC"
                     /locus_tag="VH800_000550"
     CDS             34378..39321
                     /gene="scpC"
                     /locus_tag="VH800_000550"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEQ8361639.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPT
                     ITNHAQQQAQHLTNTELSSAESKSQDTSQITLKTNREKEQSQDLVSEPTTTELADTDA
                     ASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFD
                     EDWENFEFDAEAEPKAIKKHKIYRPQSTQVPKETVIKTEETDGSHDIDWTQTDDDTKY
                     ESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDIMGSAESLFIKAIED
                     AVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDP
                     LATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVD
                     FKDIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKHG
                     ALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVS
                     KAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIA
                     GASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNI
                     DGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKDKTLRYDTELLTDHVDPQ
                     KGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRF
                     RDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGK
                     HFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNN
                     QDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTL
                     LGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDP
                     ETNRFKPEPLKDRGLAGVRKDSAFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQA
                     DGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKE
                     TLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKG
                     LKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGDYQ
                     YVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVRE
                     EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVED
                     RAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYY
                     NNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQ
                     ITAHFDHLLPEGSRVSLKTAQDQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRI
                     EGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKSTTSAT
                     AKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            40092..40799
                     /locus_tag="VH800_000551"
     CDS             40092..40799
                     /locus_tag="VH800_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEQ8361640.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVIL
                     TGIAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            41042..43039
                     /gene="metG"
                     /locus_tag="VH800_000552"
     CDS             41042..43039
                     /gene="metG"
                     /locus_tag="VH800_000552"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEQ8361641.1"
                     /translation="MKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEVF
                     YLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHEE
                     VVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGHE
                     VEWVSEESYFLRLSKYDDRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRTT
                     FTWGVPVPSDPKHVVYVWIDALLNYATALGYRQANHANFDKFWNGTVFHMVGKDILRF
                     HSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRYY
                     LMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGTA
                     FDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGDK
                     AQLASVMAHLAASLRLVAHVIQPFMMETSAAIMAQLGLEPVSDLSTLALADFPANTKV
                     VAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDAV
                     EIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKFYPNEQELVGKKLQIVAN
                     LKPRKMMKKYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            43534..44547
                     /gene="nrdF"
                     /locus_tag="VH800_000553"
     CDS             43534..44547
                     /gene="nrdF"
                     /locus_tag="VH800_000553"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8361642.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            44551..45039
                     /gene="nrdI"
                     /locus_tag="VH800_000554"
     CDS             44551..45039
                     /gene="nrdI"
                     /locus_tag="VH800_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8361643.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVSKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            45006..47186
                     /gene="nrdE"
                     /locus_tag="VH800_000555"
     CDS             45006..47186
                     /gene="nrdE"
                     /locus_tag="VH800_000555"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8361644.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYSDGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(47389..48141)
                     /locus_tag="VH800_000556"
     CDS             complement(47389..48141)
                     /locus_tag="VH800_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEQ8361645.1"
                     /translation="MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLIYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            48582..49148
                     /locus_tag="VH800_000557"
     CDS             48582..49148
                     /locus_tag="VH800_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361646.1"
                     /translation="MKWSGFMKTKSKRFLNLATLCLALLGTTLLMAHPVQAEVISKRD
                     YMTRFGLGDLEDDSANYPSNLEARYKGYLEGYEKGLKGDDIPERPKIQVPEDVQPSDH
                     GDYRDGYEEGFGEGQHKRDPLETEAEDDSQGGRQEGRQEGRQGHQEGADSSDLNVEES
                     DGLSVIDEVVGVIYQAFSTIWTYLSGLF"
     gene            49422..49673
                     /locus_tag="VH800_000558"
     CDS             49422..49673
                     /locus_tag="VH800_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361647.1"
                     /translation="MPEKKVLPVLSIVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLVLAALAVAVVAYAYYDPTVIPY"
     gene            complement(49767..50399)
                     /locus_tag="VH800_000559"
     CDS             complement(49767..50399)
                     /locus_tag="VH800_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361648.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDEQSSTQKPVKFDLDGPQQKI
                     KDYSGNTITLEDLYVGSKVVKIYIPQGWWVYLYRQCDHNSKERGILASPILEKNITKT
                     DPYRQYYTGVPYILNLGEDPLKKGEKLTFSFKGEDGFYVGSYIYRDSDTIKKEKEAEE
                     ALQKKEEEKQQKQLEESMLKQIREEDHKPWHQRLSESIQDQWWNFKGLFQ"
BASE COUNT        15905 a         9715 c        10479 g        14828 t
ORIGIN      
        1 gtctacttcc tgtcactttt actaaagaca agaatacaaa aatgagatag ttagtagtac
       61 taacagtaaa agaggtttgt ctattttaaa aatagtatca aaaaaaggtc ttttaggttt
      121 aaaacattga actgacccca aattgaccat ctaagaagtt gatgctttca aatgctgtcg
      181 cgtatggtat aataggcgca tggttattac atcaaaagca aatcaactaa ttaagcaaac
      241 aaaaaaatta ttgcaaaaaa agcatcgaaa acagtcctat ttgattgagg gctggcacct
      301 ttttgaagaa gcccaaaaat caggacaagt ttttcgccac atctttgttt tagaggaaat
      361 ggtggagcgt ctagcaggtg agcaagaact cgttattgtt agcccacaag tgctcaagga
      421 gttgactgac tctcctagtc cacaaggcat tgttgctgag gtggagatac ctaagttagc
      481 ctttccatca gattacaaag ggaaatattt ggttttagag gacgtccaag acccaggaaa
      541 tcttgggacc atcattcgta cagcagacgc tgcacggttt gatggggtct ttctttctga
      601 aaaatcagca gatatttaca accaaaaaac cctacgttcc atgcaaggta gccattttca
      661 tttaccaatt tggcgaacag atgtctatca gctttgtcga gagctccaag agtatgaaac
      721 tcccatccta gcaacaactc tgtcaaagaa atctgttgat tataaaagcc tcacacatca
      781 tgaaaggtta gctttggtgt tgggaaatga aggccagggc attagtgctg aaatggcagc
      841 cctagcagac caactggttc atattacaat gcctggtcag gcggaaagtt tgaatgttgc
      901 cgtagcagca ggaatcctca ttttcagctt gatttaagct aatatgatat aataaccaag
      961 tgaggtaatt atgttatgca ttatacagaa gataaagaat atatggaaca cgtcggtcat
     1021 ttgatcgctc atcctcgctt tcaaaaattg agtcatattg ttcagcacca acattcaacg
     1081 cgtcttgaac attctatcaa tgtttcttat tcaagttata aattagccaa gcgattcggt
     1141 tgggatgcta aaagtacagc cagagggggc ttacttcatg atttctttta ttatgattgg
     1201 cgcgtgacca agtttaataa gggtcatgcc tgggttcatc ctcgtattgc tgtacgaaat
     1261 gcgaaaaagt taacagaact caataaaaaa gaagaggata tcattctaaa acacatgtgg
     1321 ggagcgacca ttgcttttcc gcgttacaag gaaagttata ttgtgacaat ggtagataaa
     1381 tactgggctg tcaaggaagc agtgacgcct ttgagacaaa aatggtctaa tcgacggttt
     1441 cttcgccgca agaccctcca aagtcataat cgttaagtaa aggagttatt atgaacgatc
     1501 acgttattta tacacaatca gatgtgggat taaatcagtt ttttgctaaa atttatagtc
     1561 tagtgggaat gggagtgggt ttgtctgctt ttgtttctta tttgatgctt tatccattta
     1621 gagaaaattt aatctctatt cttgttaatc agccgatgat ttactatggt gctgcgatta
     1681 ttgaacttat tttagttttt gtagccagta gtgcagcacg aaaaaacaca ccagctgcat
     1741 tgcccatttt tcttatctat tctgcgctaa atggctttac cctaagcttt attattgtgg
     1801 catacgctca aacgacagtt tttcaagcat ttctttcttc agcagctgtg ttttttgcca
     1861 tgtcaatcat tggtgtcaag actaaacggg atatgtcagg tcttagaaag gctatgtttg
     1921 ctgctttgat tggtgttgtt gtggctagtc tgattaatct ttttattggt agtgggatga
     1981 tgagttatgt cattagtgtg atttccgtgc taattttctc aggtctcatc gcatcagata
     2041 atcaaatgat taagcgcgtt tatcaagcaa caaatggcca ggttggtgat ggctgggctg
     2101 ttgctatggc cttaagcttg tatttagatt ttattaactt atttatcagc cttcttcgta
     2161 tttttggaag aaatgattaa cattaaaaag tgagtataac tactcacttt ttaatgttaa
     2221 caggataagt aaactgtaag gaagaaattc gagatagata taagatgagg ctgctaaaag
     2281 acctagtgtt aatttgtaaa ctctttcttt ttttggtata ctattaagga ttaaatacga
     2341 ggagaatata gatagatatg tcaacagcta tttggatttt attacttatt gttgcccttg
     2401 gggtaggtgt ttttggtggg atttttattg cccgtaaaca aattgaaaaa gaaattggtg
     2461 aacacccacg tttaacacca gaagctatcc gtgaaatgat gagccagatg gggcaaaaac
     2521 caagtgaagc aaaaatccaa caaacttatc gtaatatcat caaacaatca aaagcagccg
     2581 tatccaaagg caaaaaataa aagctaattg ttatagggga aacctttgtg atagttagaa
     2641 gtgaacagtc tttgatctca atgttcagta gcacttgtct tatcagttag atttgtcaac
     2701 tgttcagggt ttaaaaagaa actcagttgg ctatttccaa ctgagttttt catatcgtca
     2761 gtaaggaagt aaacataatg gatacaagac caattgggtt tttagattct ggtgtgggag
     2821 gtctgaccgt cgtttgtgaa ttgattcgtc agctccctca tgagaagatt gtatatattg
     2881 gtgattcagc aagagccccc tatggtccta gacccaaaaa acaaattaag gagtatactt
     2941 gggagctagt caattttttg ctgactcaaa atgttaaaat gattgttttt gcatgcaata
     3001 ccgcaacagc ggtggcttgg gaagaagtaa aagcagcttt agatattcct gttttaggag
     3061 ttgtcttacc gggggcaagc gcagctatta aatcaacgac aaaaggccag gttggggtca
     3121 tcggaacccc aatgacagtg gcttcagaca tttatcgcaa aaaaatccag ctattagcac
     3181 catctattca agtaaggagt cttgcttgcc cgaagtttgt accgattgtg gaatcaaatg
     3241 agatgtgttc gagtatagct aaaaaaatag tttatgacag tctagcacca ttagtcggta
     3301 aaatagatac ccttgtacta ggatgtactc actatccctt gttacgacca attatccaaa
     3361 atgttatggg gccatctgtt aagctgattg acagtggagc agaatgcgtc cgagatatct
     3421 ctgtcttatt aaactatttt gacattaacg gtaattatca tcaaaaagct gtcgaacacc
     3481 gcttttttac aacagcaaat cctgagattt ttcaagaaat tgcctcgatt tggctgaaac
     3541 aaaaaataaa tgtggagcat gtcaccttat gagtgaaaaa atttacgaat acaaagatga
     3601 aaataactgg tttatcggaa agatgactgg tcataattta atatcgggct ggggagtcaa
     3661 acacacgaca atcaaaaaaa tagatgacct tttagacggt attgccgcaa cgttagattg
     3721 ggaaaatcct aaaggttacg atgtttcggt ggtgcgtcat cagtctcctt tatctctcat
     3781 cacctttatt atcgacatga taaatcaaga gacccagcgt gagattaagg taactcccca
     3841 tgcaggcacg attttattaa tggaaaatgc gaaactgctt gcagtttatc tcccagaagg
     3901 tggagtttca acggctacat tttttgcgac tagtgaacag ggatttgggg atattatttt
     3961 aatcgctaca cgaaacgagg gaaaaaccaa agagttccgc aatctgtttg gccagctagg
     4021 ttatcgtgtg gaaaatctta atgattatcc agaattgcca gaagtagcag aaactggtac
     4081 tacttttgaa gaaaatgctc gcttgaaagc agaaacgatt tcacgcctca caggaaaaat
     4141 ggtattagca gacgattcag gactaaaagt tgatgccttg ggtggtttac ctggtgtttg
     4201 gtcagctcgt ttctcaggac cagatgccac agatgccaag aataatgcca aactcttaca
     4261 cgaattagct atggtgtttg accaaaagaa gcgctcagct caatttcata cgactttggt
     4321 agtggctgct cccaataaag atagtttggt tgtggaagcc gattggccag gctatattgc
     4381 tacgcagcct aagggagaaa atggttttgg gtatgatcct gtctttatcg tcggagagac
     4441 tgggcatcat gctgcagaat tagaggctga ccaaaaaaat cagttgtcgc atagaggtca
     4501 agcagttcga aaattaatgg aggtctttcc agcatggcaa gcaaaacaat catagtaatg
     4561 agtgactctc atggtgaccg agatatcgtt caagccatta aagacaagta tcttggtcaa
     4621 gttgatgcta ttttccataa tggggattct gaattaaaca gctcagatcc tatttgggct
     4681 ggtatttatg tcgttggcgg taattgtgac tatgatacag gttaccctga tcgtttagta
     4741 actcaattag gcacagttac gattgcccag acacatggtc acttgtacca tattaatttc
     4801 acttgggata aactggacta ctttgctcaa gaagtagtag cagatatttg tctatatgga
     4861 cacctacacc gtccagctgc ttggcaagtt gggcaaaccc tctttatgaa tcccggatca
     4921 gtaacacaac ctcgcggaga aattaacgag aaattatatg ctcgtgttga actaactgat
     4981 actcaaatta aagttgatta ctttaccaga gatcataaac tttacccatc actgtctaag
     5041 gaatttaaac gatgatcgca aaagaatttg aaacattttt aatgagtcat ttagataatt
     5101 atcttatccc ggaacaagac ttggctattt ttatcgacac acataatgca gaccatgtga
     5161 tgttactatt ggtgagcaat ggtttttcta gagttcctgt tatcacacgg gagaaaaaat
     5221 atgtgggaac cattagcatc tcagatatta tgatgtacca atctaaaagg cagctgacag
     5281 attgggaaat gagtcaaaca gatattggcg agatggttaa taccaaaatt gaaaccatta
     5341 gcattacttc tagcctaaca gaaattatgc acaagttaat tgatttccca ttcttaccgg
     5401 ttgtagatag agcgaatcgc tttgttggga ttattacgcg aaaatctata ttaaaggctg
     5461 tcaacagtct tttacatgat tttacagatg attacacgat tataaaaaaa tgaagagtta
     5521 tattgaacct tttattgcta gcaaggcttt atctcaaaat agtcaaaaag cttatcgata
     5581 cgatttgcaa cagttttgtc aactgattgg tgaacgtgtc aatcaagaca aactattact
     5641 ttatcaaaat agcatagcta acctaagttt atctgcaaaa aaacgcaaat tatcaacagc
     5701 taatcaattc ttatattact tgtatcaaat aaagtattta aatagctatt ttcgattaac
     5761 agacaccatg aaagtgatgc ggactgagaa gcagcaagct gctattatta atactgatat
     5821 tttctatcaa aaaacccctt ttgtgtgggg gcaattaatc agcttattaa tattggagct
     5881 gggtttaact ccgagtgaag tagctggtat tgaagtagct aacttggatt taaattttca
     5941 aatgttgacg ctaaagacta aaaaaggtgt gcgtgtatta cctttatcgc aaatactaat
     6001 ccctttttta gaacaacaac tcgttggcaa agaagtctat ctttttgaac atcgaggcat
     6061 ccctttttca agacaatggt tttttaatca cctaaaaacc tttgttcgaa gtattggtta
     6121 tgaaggattg actgctcaaa aattacgaga gcaatttatt ttgaaagaaa aactagctgg
     6181 taaatcgata atagaactta gcgatattct tgggctgaaa agccctatga ccttagaaaa
     6241 atactacaaa tcataatgga tataaaactt aaagattttg aaggtcctct tgatttactc
     6301 ttacacttgg tatcacagta caaagttgac atctacgagg ttcctattgt tgaggttatt
     6361 gagcagtacc ttaattatat tgaaacctta caggtaatga aacttgaagt ggctggtgac
     6421 tacatgctga tggcaagtca gctcatgtta atcaaaagta gaaggctatt accaaaggtg
     6481 gtagaacaca tcgaagaaga tttagaacaa gatctgttag aaaagatcga agaatatagt
     6541 cgctttaaag cagttagtca agcgttagcg aagcaacatg accaaagggc aaaatggtat
     6601 tcaaaaccta aacaagaatt aatttttgaa gatgctatct tacaggaaga taaaacggtg
     6661 atggatctat ttctagcttt ttcaaacata atggcagcta aaagagcagt tttaaaaaac
     6721 aaccatacag tcatcgagcg tgatgattat aagattgaag acatgatggc ttctattaaa
     6781 cagcgactgg aaaaagaaaa cgttattaga ttatcagcga tttttgagga atgccaaaca
     6841 ttaaatgaag ttatcagtat atttttagct agtctagaat tgattaagct tcacgtggta
     6901 tttgtagagc agctctctaa ttttggggct atcatactac gaaaggagaa gaaatgacgt
     6961 atttgtcaca gatagaagcg ctgctattta ttgcaggtga agaaggatta agtttgcgac
     7021 atctagcgtc tatgttatca ttaacgccaa cagctcttca acagcaatta gaaaaactct
     7081 ctcaaaagta tgaaaaagat caacattcta gtctttgctt gatagaaaca gctaatacct
     7141 acaggctagt aactaaagaa ggttttgcag aactcttgcg tgcttatgcc aaaacaccaa
     7201 tgaaccaaag tttatctcgt gcgagtttag aggtcttgtc tattgttgca tacaaacaac
     7261 ctattacacg aatagaaatt gatgacattc gaggggtaaa ctccagtgga gctttgagta
     7321 aattattggc atttgatctc attagagaag ctggcaaaaa agatgtggtt gggcgtcctc
     7381 atttgtatgc gacaacagat tattttctgg actatatggg aattaatcat ttagacgaat
     7441 tgattgaagt atctgccgtt gaaccagcag atgaagagat tgctcttttt aggacacaag
     7501 actgagtttt gcttgtcatc aaatagcaaa tggcgtttac aaaaggattt gttttaaggc
     7561 gttttagttg aaaaaaaagc cttaaactag ggacaacaaa aagttgctca aaagaaagaa
     7621 gaatataatg cgaattaaca aatacattgc ccatgcgggt attgccagtc gtcgtaaggc
     7681 tgaagaattg attaagcaag gcttagtaac cttaaatggt caggttatta cggatttagc
     7741 aaccactgta aaatcgggag acgtggttga aatagaagga agtcctattt acaacgagga
     7801 aaaggtttac tatttgctta ataaacctcg tggcgctatc tcaagtgtgt cagatgacaa
     7861 aggccgtaaa acggtactgg atttactacc tcaggttaaa gaacgcatat accctgttgg
     7921 acgattggat tgggacacat caggggtcct tattttaacg aatgatggtg attttacaga
     7981 tactatgatt catcctagaa atgaaataga caaggtttat ctggcgcgtg tcaaaggtat
     8041 tgcaacgaaa gaaaatcttc gtcccttaac tcgaggaatt gttattgatg gtaaaaagac
     8101 caaaccagct cgctacaata ttgttcgtgt agaagctgat aagagtcgat cgatcgtaga
     8161 attgactatc catgaagggc gaaaccatca agtgaaaaaa atgtttgagt ctgtggggct
     8221 tctggttgat aaattatctc gtacacgttt tgggaccgtc gacttaaagg gactaagacc
     8281 aggagaagca agacgcttaa ataaaaaaga aataagtcaa ctgcataact tagctaatac
     8341 gaaaaaatga tgaaaaaact attaatagta tctgttaaag cttatcaaaa atacatttct
     8401 cctttatctc ctcctagttg tcgctacaag ccaacctgtt cagcttatat gttaactgct
     8461 attgaaaaac atggtactaa gggaatatta atggggatag caagaatatt aagatgtcac
     8521 ccttttgttg ctggtggtgt cgatcctgtt ccagaagatt ttagcctaat gagaaataaa
     8581 aacacgtcta aaaacgctga aaaggcatga ctttatcaaa aaatggcttg acattgatag
     8641 ctgaagtgtt ataatggaaa ataagcattc gttggtttaa atcaaacctg ttatgattta
     8701 agttagcgag tcaccatcaa ccacattgtt tgctgagcat gactccgagc agtgtggttt
     8761 tttaaattaa aaagagtaaa tgagattatg acgacaaaag aacttatcaa caaaaacgac
     8821 aaagtaaaaa aggctcgcaa tcatattgtc ctgtttcaac cccaaattcc acaaaatact
     8881 ggtaatattg ctagaacatg tgctgcaact aatgcacctt tacatattat taaacccatg
     8941 ggatttccta ttgatgaccg caaaatgaag cgtgcaggct tggattactg ggacaagtta
     9001 gaactgcatt tttatgatca tttagaacag tttatcaatc aatgtcacgg acagcttcac
     9061 ctgattagca agtttgcagt taataattat tctcaagcta cttatgctga tggcgattcc
     9121 cattatttct tgtttggacg agaagataca ggcctgccag aagattttat gcgagaacat
     9181 gctgaaaaag cacttcgtat tccgatgaat gatgagcatg tacggagttt aaatgtctca
     9241 aatacggttt gtatggtgat ttatgaagcc cttagacaac agggctttca agggttagag
     9301 ttaaagcata cttacgaaca cgataaacta aaataatgga ctttttaaaa gcgtcagttt
     9361 ttggcaacat gcgttgtcag tagctgacgc ttttaaaaat ttagtcaaag ctattgctat
     9421 ctaggtttaa atctgctatg ctagaagtgt cttcagggca gggtgtgatt cccgaccggc
     9481 ggtgactagt aactagaagt ccgcgagcgc aagctgatgt ggtgtaactc cacaaccgac
     9541 agtatagtct ggatgagaga agaccgggct ttttgtgtag gcttatttta gctacacaat
     9601 aacgacggaa cttctttcaa tttgaaaaaa ttggaggaat tttttaatgt caaaaacaca
     9661 taaaatgatt atgattggta tactttctgc gatatcattt ctattgatgc tagttagctt
     9721 tgccattatt ccaggcgcag cttttttaaa aattgaattt agtattattc ctgttttatt
     9781 tggtttaatg attatggact taaagagtgc ttacttaatt ttgttattga ggtccttatt
     9841 gaaactcttt ttgaacaatc gtggggttaa tgattttatt ggtctcccaa tgaatattat
     9901 cgctatcgct ttatttgtga cggcttttgc cttagtttgg aaccgtcaaa aaacgcttag
     9961 tcaatatgta tttgctagct tactaggcac agggttatta acgtttggca tggttgttct
    10021 taattatact tttgccattc ctttatatgc tatatttgca aatattgata tcagagctta
    10081 tattggtgtt actaagtata tgatgactat ggttattccg tttaatcttg ttgaagggtt
    10141 gatatttgca attacctttt attttgtgta tattgcaagt aaaccaattt tagaaagata
    10201 cttacactaa tatgatgaca aacaaacaaa ctcacttttt aatagcttct tttgcattgc
    10261 taatctttgt tataataggc tatacggtca aattttttcc tgaacgtttg gcacttctag
    10321 ataatactat tcaagcagag attagaggca accttcctat agtgctgacg caattcttta
    10381 ggggtgttac tgtatttgga aatgtcatga cacaagtttt gttagttatt gtgtcggtcc
    10441 tagttttatt ctttatgaag tggaaaattg aagccttgtt tatcttgtca aatggtgcca
    10501 ttgcagcatt tttgattacg actctcaagc tcttttacca aagaccaaga cctgctattg
    10561 agcatttggt ttatgctggt ggctattcgt ttcccagtgg ccatgcgatg ggtagcatgc
    10621 tgatttttgg tagcctattg attatttgtt atcagaggct acattcaaaa ctattacaat
    10681 ttgtgactag catgatcttt ataatactaa ttttattaat tgggttatct cgtatttatc
    10741 taggagtaca ctacccaagt gatattttag caggctttgt attaggattt ggtattttgc
    10801 actttattta tcctttttat aagcaaaaac gatttgaatg gcgatttctt ttgaaacaag
    10861 actaattttt cttgagaaga cataggctta tttaaatcat ttagaataac attggcaagc
    10921 atcaccccct tgattgccag tgttatttta gttttagtta gatgatgtga gctgatgatt
    10981 agtaaatatg tttagataaa aaacgattaa agtgctatgt aacgtcagaa aagacgtgat
    11041 ttttgttgat ctgtaatcat taagtaagct gatgtagaag tagtgaattc taatgactga
    11101 gctatctttt gcatagatga ctatcttgct agtaatgatt tgtgctacaa tagaaacatg
    11161 aaaaaaagat atcagacatt aaatgagcat taccgtcaac tatttggcgc aaaaatgttt
    11221 aaagttccga ttgatgccgg ctttgattgt cccaatcgtg atggaacggt agctcatgga
    11281 ggatgtactt tttgcacagt atcaggttct ggagatgcta ttgtagcacc agatgctcca
    11341 attaaagagc aattttataa agaaattgat tttatgcacc gtaaatggcc tgatgtcaat
    11401 cgctatttgg tttattttca aaactttacc aatactcatg atacagttga tgtgattcgc
    11461 gaccgttacg aacaagctat taacgaacct ggagttgttg gtattaatat tggcacacgg
    11521 cctgactgtc taccagatga taccattgct tacttagcag aattatcaga acgcatgcat
    11581 gtgacagtgg agctaggctt acagacaact tatgaagaaa cttctaggct aattaacaga
    11641 gcacattctt atgatttgta taaagaaacg gtgaggcgac taaggcatta ccccaacatt
    11701 aatattgtct cgcacttgat taatggattg ccaaaagaaa ctcatgacat gatgcttgaa
    11761 aatgtgagac gctgtgtaac agacaatgac attcaaggaa ttaaattgca tttgctgcat
    11821 ttgatgacca atactagaat gcaaagagat tatcatgaag gacgcttaaa gttgttgagt
    11881 caaaaggact atgtttcgat tatttgtgac cagctagaga ttatccctaa gcatattgtg
    11941 attcaccgta ttacaggaga tgccccacgc gatatgttga ttgggcccat gtggagtcta
    12001 aataagtggg aagtattgaa tgccattgat aaagaaatgg aaagacgagg aagctttcag
    12061 ggctgtaaag ttgactaatt tgtctcattt tgacggattt ggataggaga aaagtgatgc
    12121 taaaacgccc cattcatctc tcgcatgatt ttttagcgga ggttgtggat aagtctagtg
    12181 tggttgttga tgccacgatg ggtaatggaa atgatactgc ctttttggca caattagcta
    12241 aaaaggttta tgcttttgat gtgcaagaac aagctattag aaaaacaagt gagcggttag
    12301 cgcagctagg attatcgaac gctgagctga ttttagcggg tcatgaagcg gttgatcagt
    12361 atgtgacaga gccggtgcgc gcagcgattt ttaaccttgg ttatttgccc agcgcagata
    12421 aatctattat taccttacca aataccacac tccaagcttt atcaaaacta ctaacgttat
    12481 taatggtagg tgggcgtatt gctattatgg tctattatgg gcatgatgga ggcagtttgg
    12541 aaaaagatgc tttattagat tttgtcaagc aattagacca aagaaaggtt tctgcaatgc
    12601 tttatcagcc tcttaatcag gtgaataccc cacctttttt aatcatgttg gagaaattag
    12661 cagactttta gctcttatcc ctgtgtcaag tctactagaa gttctgcgat tatttcggtg
    12721 gaaaaagaag aaatcccata ggctttggct ataaatgtga tataatgaag tcactatatt
    12781 atttttttag gagttacatt aacatggaag accctgtgag tcagccctta gtgattcaat
    12841 ttttattgtt agttgtttta accttgttaa atgctttttt ttcagccagt gaaatggcct
    12901 tagtttctct caatcgttct cgggtggaac aaaaagcagc agacggtgat aaaaaatacg
    12961 ctcgtttgtt gcgggtttta gaggaaccta atcatttttt atcaacgatt caagttggga
    13021 ttacctttat tagtttacta tcaggagcaa gtttatcagc ttctttgggt aaggtgatct
    13081 caggttggct aggtaattca gcgaccgcaa ggacagctgg tactatcatc tccttggttt
    13141 tcttgactta tgtctctatt gttttaggag aattgtatcc aaaacggatt gccatgaacc
    13201 tcaaagacaa gttggcgatt gtttcagccc ctattatcat tgggttaggg agactggtta
    13261 gtccctttgt atggctctta tcagcttcta ctaatttact gagccgactt acccctatga
    13321 cctttgatga tgcagatgag caaatgacac gtgatgaaat cgagtatatg ttatcaaaaa
    13381 gtgaggcgac ccttgatgct gaagaaattg agatgttgca aggagttttc tcacttgatg
    13441 aaatgatggc gcgtgaagtc atggtcccaa ggaccgatgc tttcatgatt gacattaacg
    13501 atgatccgct tgaaaatatt caggaaatct taaaacaaag tttttcacgc attcctgttt
    13561 atgatgtgga taaagataaa attatcggtc tcatccacac taagcgtctc ttggagtcag
    13621 gtttccgcca gggatttgat cagattaaca tgcgaaaaat gttacaagaa cctctttttg
    13681 ttcccgaaac catttttgta gatgatctct tacgccagct gcgcaatacc caaaatcaga
    13741 tggctatttt gctagatgaa tatggtggtg tggcaggact tgtgactttg gaagacttgc
    13801 ttgaagaaat cgtcggtgaa atcgatgatg aaaccgataa agcagaacaa tttgttcatg
    13861 agattggaga caatacctat attgttgttg gtactatgac tttaaatgag tttaatgact
    13921 attttgatac cgaactagaa tcagatgatg tagataccat tgctggtttt tatttgacag
    13981 gtatcggaac cattccaagc caggagcaaa aagaagccta cgaaatagat aacaaagaca
    14041 aacatttagt tctaatcaac gataaagtca aagatggccg tattacgaaa ttaaaattaa
    14101 tcctgtctaa tatagaacag attattgagg aagactaggc tccatgccta gtctttttga
    14161 tgaaaagtgt tataatgaaa atgtaaaaac gtttacaagt aatgaaggag atgcaatgac
    14221 tgagaaagat tatggacaag taacagggat ggtgcattcg acagaaagtt ttggttctgt
    14281 agatggtcca ggcattcgtt ttatcatttt cttgcaaggc tgtaaattac gttgccaata
    14341 ttgccataat ccggatactt gggagatgga aaccaacaat tcaaaaatca gaacagtcaa
    14401 tgatgtcttg aaagaagccc ttcagtacaa acatttctgg ggaaaaaaag gaggaattac
    14461 cgtatctggt ggtgaagcta tgcttcaaat tgattttatc actgccttat tcatcgaagc
    14521 taaaaaatta ggtatccata ccacactaga cacctgtggc tttacctata gaccgacacc
    14581 tgaataccat caggttcttg ataacttatt ggcagtgacc gatttgattt tattggactt
    14641 aaaagaaatt gatgaaaaac aacataaaat tgtcacgcgt cagcctaata aaaacatatt
    14701 gcaatttgct aggtatttat ccgacaagca gattcctgtc tggattcgac atgtcttggt
    14761 tccaggcttg actgatattg atgatcattt gacacgattg ggtgagtttg tcaaaacctt
    14821 gaaaaatgtc gataaatttg aagttttgcc ttaccatacc atgggagaat tcaagtggcg
    14881 tgagctaggt attccttatc agttagaagg tgttaaacca ccaactaagg aacgcgttca
    14941 aaatgctaaa aatctgatgc agaccgaatc ttacacagaa tatatgaatc ggattcatca
    15001 gtcataagag ctgttatagg gttgaggttt cttcaacttt ttaaagtatt ataagcagat
    15061 cttttgtaat cttcctttga ttttaggggg taattttgct aaaataaaat gaataaacaa
    15121 aatgaggtag aatgattatg tcaaaaattt tagtttttgg tcatcaaaat cctgatacgg
    15181 atgctattgc atcatcttat gcttttgatt acttatccca aaaagcgttt ggtttggata
    15241 ctgaagtcgt agctttagga acacctaacg aagaaacagc ttttgccctt gattattttg
    15301 gtgttgaggc accacgtgtg gtagagtctg ctaaagcaca agggtctgaa caagtgattt
    15361 tgacagacca caatgaattc caacaatcca ttgcagatat ccgtgaggtt gaggtatatg
    15421 gtgtggttga tcaccaccgt gtggctaatt ttgaaactgc aaatccttta tacatgcgtg
    15481 tggaaccagt aggatcagcc tcatctattg tttaccgtat gtttaaagaa aatggcatcg
    15541 aggtgccaaa agcgattgca gggatgctct tgtctggttt gatttcagat accttgttgt
    15601 tgaaatctcc aacaactcat gtgtctgatc accttgtcgc tgaagaattg gcagagctag
    15661 cagaagtgaa cttggaagac tatggaatgg ctcttttaaa agcaggtaca aaccttgcaa
    15721 gcaaatcaga agtagaattg attggtattg atgccaaaac atttgaatta aatggcaatg
    15781 ctgtgcgcgt ggcacaagtg aacactgttg acattgcaga agtcttagaa cgtcaagaag
    15841 ctattgaagc agccattaaa gatgccatgg ctgcagaagg ttattcagat tttgttttga
    15901 tgatcacgga tattgttaac tcaaactctg aaattctagc tattggagca aacatggaca
    15961 aggttgaagc agcctttaac ttcacccttg acaacaatca tgccttctta gcaggtgccg
    16021 tttctcgtaa aaaacaagtg gttccacaat tgacagaaag ttttggagct taatgaaaag
    16081 acgctttaaa aggacttgat ttttttgacc aagtcctttt gtcactcttc tatgttataa
    16141 tagaaggtat gataacagta tttcattcag ataaactcac cagacaacct ttctttcaag
    16201 accttatcaa ttatctcgac cagcatgatc acgttatatt acgagagatc aaaaaagcct
    16261 ttcctaatgt gacaggtatt gacaaggcca tcgaaagcta tgttcaagct ggctatattc
    16321 gccgtgaaaa taagcgttat ggcatcaatc ttcctttggt gagttctgat cagcagctgg
    16381 ccttagacac tatgcttttt gtggacacct gttcagctat gtatgaaaat attttagcgg
    16441 ttgtttttga gactcagcta acaaaccaaa ccaatcgcgt gatgatcaag gaaaagacca
    16501 acatcacgag agacgatttg accctggcta attattttta ccgtctcaaa agaggtgaga
    16561 agccatcagc tgagcagatg gacttgtatg acctcttggg ggatgtgaat caggaatatg
    16621 cccttaaata tatgacaact tttttgctta aattcacgcg caaagacttt gtgatgcaaa
    16681 aacgtcctga tatatttgtg gaagctctgg ttacacttgg ttacctaaaa caagtggagc
    16741 ctacaacata ccagctgcta atgaccttgg ataaagaaag tttaaccttt atagcaccat
    16801 agaaaagagc taggaacaag gactgttctt agctttttga gtgcttttat tttgtttttg
    16861 ccattaagta aagaaaataa ggggctccga taagcgacac taaaatccct gtctggatat
    16921 tactgccaac cagatagact cgtcctactg tatctgcaac aagaagtagg atcattccga
    16981 ttaaaatact aatgggtatt gttattttat gattactccc taccaagtat gtactaaagt
    17041 gtccagctat taagccgata aaactaatat taccaaccaa aagaacactc aaagcaccta
    17101 agccagctgc taagacaagt atcaaacgac gcttacggtt taaagggagt cctagcccaa
    17161 tagcagtatt atcagctaat cccataatat taaggaaatg ggcttgacta taagtcaata
    17221 gccaaaaaca caataacaaa ggagcgatga cactcagagt aggccagtcg tctcctatca
    17281 attggccgct aagccaattg atgaccaaat cgactttgta gcgattaata tgaccaacaa
    17341 gagcaaccat tagacttgaa agcatggtag taacagctac accagtaaga attaaccgtg
    17401 taggatcaat ttgtccttgt tttgtcaaag atagccaata aacgctaaag gttgttacaa
    17461 tagcaccaag catggcaaat aaaggcaagt aatggctgat atgagcttgc tcaaagaaag
    17521 aaaaggagac cacaatagcc aaagagatac ctgctcctat agtaatacct aatacaccag
    17581 agtcagctaa gggatttcgt gttaaacgtt gtaataatag ccctgataaa gcaagagaac
    17641 cgcctcctag acaagcagct agaattcttg gcagacgaat gttaataacg atgaaagata
    17701 tggcatggct agattttccc aaaaacacat ggacaaggtc caaaaaagat agatgagatt
    17761 ctccaaggga caaagctaat cccataagac ttacaagtag caggatcagg ctagtatata
    17821 accttaaaag gtgtctttga gatttcaata gcggcctcct cttcttatta accataaaaa
    17881 gcatggaaaa ccaattaagc taaccaatgc cccaagaggg gtttcataag gcggattgag
    17941 attacgacaa gcaatatcaa cccataccat gaaactagcg ccagaaactg cacaaagcgg
    18001 caaaaggtat cggtaatgat gaggtgtaaa atgtttcata agatgaggaa tgactaagcc
    18061 gataaaagaa atgcttccag caatggctac agctgctgat gataaaataa gaaccaaaat
    18121 cataaagact gcactgatca agttggtttt ttgcccaaga gcttttgcct gagactcact
    18181 tagactaagg acggtcaggt gataagataa tagctgggct aaacaaagac taagaataat
    18241 aagaggagca atatagccga tcatttgcca attgaccccg acaagacctc ctgcttgcca
    18301 gccgataaca gcatttgcca gatgatagta attggtaata ccttgaccta atgctgatag
    18361 cagtatggaa accatagctc ctgctaagac aaggcggagc tgatggtagc ctttgccaga
    18421 ttgataagaa aggccaaaga ctaaggttgc tgccaggcta gaccctaaca acgaaagcag
    18481 aataatgagg gaatagtgca agtgaggtac aaacgcataa gccagtacca aggctagtcc
    18541 tgctccagca ttaatgccta aaaggccagg ctcagcgata ggattacgtg tgattgcttg
    18601 catgatagtt ccagaaacag ctaacgcaga gccagttaag gtagcaccaa aaagtctcgg
    18661 taatcgtata gcgagtaaaa cattggcttt atggccgttt tgctttccaa ataaaataga
    18721 gttaagatcc tgatgtgata aagcaacggc tccaaagcgc agatgacagt aaatagcaac
    18781 acataagcta aaactaagta gcacaaagac aagccaaaag atatgtgact tagtgattat
    18841 ctgcgttttt tttaagcaaa aacgctcgag acacaaaaag ggatgcttag ttttcacttg
    18901 ataagattgc ctctcgtaaa gtctctaatt gatattctaa agaaagagga tcagtaaagt
    18961 aaaaaacatt ggcattgact ttgatcacat ggtgtttttt cacagctgga atggattgcc
    19021 atagcttgct ttcatataga gcagaaccag tcttatcatc ttctgcagca acgacgacat
    19081 aatcaccaat atagtctggc aagacttcct gcgacaatga caggtaacct tgtttaaaaa
    19141 cttcagtctt cactttttca ggagcatcat aatggaaagc ttgatggata atctctccgc
    19201 cacgtcccca gtctttacca aaaaggtaaa cgtctttttc ataaagcccc ataatagtaa
    19261 aggttgcttt gtcacctgta acggccttga cttctttttc ataagctgct gttttagttt
    19321 tccaatcttt taaccacttc ttggctttgt cttctttgtt aaagatgcgg ccgaagtcag
    19381 ataacacttg taaataatca cgtttgcggt attcaatcga gataacaggc gcaatttctg
    19441 ccaattgttt aatattttct tctgtagagc caacaacaat gaggtcaggc ttaagcgttg
    19501 taacggcttc taaatcagtt gcagcaactt gctttgcttt ttttacagtc tttgctaaga
    19561 tggggttttt cttgtcataa gaagtaaccc cgactagatt catatctaat tttttgaggt
    19621 aaccagtgta agttgaagcc agactgacta ctcgcttagg ctgtttagga atatctccgt
    19681 aataagtcac accagcaatt tgaggcatag gcgataaact ttttgaggcg gtgttagaat
    19741 gattagttgc ttgattacca caggcgatta aggtaatagt tgtcaaacag agtgttaata
    19801 gtagagttaa ttttttcatg tatgctaatt ctcctagaat aaagttattg aagctgataa
    19861 gtcagcacta taggacagtt gtggatagga tcatcaacca gtaccggttt gatttggaag
    19921 atgtcttgaa tgataggtga agtcataaca tctgctatag taccagtata atggatcttg
    19981 ccatgtttca tagcaatcag atgatccgaa tagcgggctg aaagattgag gtcgtgaaga
    20041 accataacaa tagtcttgcc ggcatcctta tttagggatt taacgagctc taggatttct
    20101 agttgatgat ttaaatctaa ataagtagtt ggctcatcta aaaaaatagt atcagtgcct
    20161 tgggctaatg ccattgcaag ccaaaccctt tgacgttgcc ccccagaaag agcatcaaca
    20221 ggttgatcag cataggccat gacattggtg gcttgcatag cccaatgaat ggcttttttg
    20281 tcagctggac taagatttcc aaagtaagat tgatggggaa aacgtccgta agaaaccaat
    20341 tcgtaaacag ttatgccgtt agttgcttct tgaacttgag gtaaaagagc tagtttttta
    20401 gcaacctctt tagtttctaa tgtggcaatg ttttgcccat ttaaatatac aactccctgt
    20461 tttggtggta ataatcttgt cagtgctttt aataaactag acttcccaca gccattggcg
    20521 ccaataatgg tcgtaatttt accttcagga atataaaacg ataatttatc gatgatggta
    20581 cgctgttcat aggcaattgt gaggtcttca gcactaattg ttgtcatatg gttgcctcct
    20641 ttctaaaaag agtcaaaggg ttgatgaaag tgcacattaa agtgttcatc tgcccatttt
    20701 aaaatagttg agaagtagct tattttctca aaatcttcac tattatagca tagaaaaaag
    20761 gcttaacaaa gccttttttg atgtgatttt taggatgtat taaaaaagaa atattagttt
    20821 agaatgatta aaaacaatag cgataatcat tctaaactaa cgtcaacata ctctagaggt
    20881 agtgtttggc gattgctaaa tcaccagcat aagctacttg ttgtccttta acaatttgat
    20941 aagcatctgc gcctttccca gcgataatca cagcatcttt tgctccttgg caaagagaca
    21001 tggctttttg aatagcttgc tcacggtcac taataatctc tactgggcgt gcgatatggc
    21061 tggcaatttc ttttgaaata tcttctggat cctcgaaatt agggtcatca gcagtgagaa
    21121 tgacggtgag gtttggatgc tgatgaatca ccctaccaaa atcagctcgt ctgctctcgc
    21181 ctttatttcc tggtgcacct aaaatcaaca ttaatttgcc tgtctgatgt tcttccacaa
    21241 cgctgagtaa tttttctaag ctgtcaccat tatgggcata atcaacaaaa actttagcat
    21301 gatttgtcat agtgaggact tccatacggc ctgggacgcg agtcttagcg ataccttttt
    21361 gaatatcagc taggctagca cccaaacgaa ggcaggcaag tccagctgcc atagcatttt
    21421 cttggttaaa atggccaatt aattgaatgt cataatggcc agctaattgt cctttagctt
    21481 caaaggagaa ggcttggcta gtggtgatct ggttgtcaga caagggacca taaaacacat
    21541 gctcttgatc cgctacctga tccgctagaa atgaaaaatg atccatcccg ctattgatca
    21601 caacagctct gctattctcc attaaaagac gcttatgata gaaataatct tcaaacgttg
    21661 gatgctcgat tgggccaata tgatcaggac taatatttag gaaaacccca acatcgaacg
    21721 taagcccata gacacggtca acgaggtaag cctgactaga aacttccata atcaagtggg
    21781 tcatgccatt agtcacacac tcagccatca tagcaaaaag atccaagctc tcaggagttg
    21841 tgagttgtga tttgaaaaag gtcttgccat ctaaggtggt attcatggta gaaaacatgg
    21901 caggtttata ggattctttc aacatgtggt aggcaaaata agcagccgtc gtctttccct
    21961 tagtacctgt aaaagctagt agtttgagct tttcttgagg gttgccatag aaagccatgg
    22021 caattagact catagctttt ttgatatcag tgaccaaaac aacgggaata ccaagctcgt
    22081 aatctacctc tgaaatatag agttgtaatc cgttagtgat tgcttcttta aggtagtcag
    22141 ctttgaaagt tgccccttta gcaaaaaaaa gggtcttgcc atctacttga cggctatcgt
    22201 aactcaagcg ctcaaaacta aagccttgat aatggtagtg gtatccgtcg gcatcaagaa
    22261 cctcacgaaa attatggtct ttttttaaaa tgtctaataa ttgttcaatg gttatcatac
    22321 ccttatttta tccttaaagt tcttgtttta caagtcacaa gcaaaagttt ataataaagc
    22381 taatagaaac taggaaagaa tagatatgtc gacagaaaaa aaacaactga cacaagaaga
    22441 attgatggtt cagggagcag cctggtccac agctggtaat ttcattagcc gacttttggg
    22501 agtgttatac attattccct ggtacatttg gatggggcaa tacgcgattc aagccaacgc
    22561 tcttttcaat atggggtata atgtttatgc ttatttttta ttgatttcaa ccacaggact
    22621 caatgttgcg attgctaagc aggttgccaa gtacaattcc atgggacaaa ctgagcatag
    22681 ctatcaatta atccgaagta ccctaaaact catgcttggt ctgggcctta ttttttcagc
    22741 cattatgtat ctgggctctc ctttatttgc gagcttatct ggtggtgatg acacacttgt
    22801 tcccattatg cacagccttt ctttagcagt ttttattttt cctgtaatga gtgtgattcg
    22861 aggcatcttt caaggccaca ataatatcaa gccttatgca gttagtcaga ttgctgagca
    22921 actcattcgg gttatctgga tgcttttgac cacctttttt atcatgaagt tgggttctgg
    22981 tgattacgct tcagcagtga ctcagtcaac ttttgcagcc tttatcggga tggtggctag
    23041 tatgggtgtt ctggggtact atctttggaa acagggactt ctagcagcta tttttagtaa
    23101 gccagatcat actgtttcta ttgatatcaa gggcttgttg cttgaaacct taaaagaatc
    23161 catccccttt atcgtaacag gaagtgccat tcaagccttt caattgattg atcaatggac
    23221 ttttgtcaat acgatgactc tttttacaga ttatagccgt tctcaattgc ttgttttatt
    23281 tggttacttt aacgcaaacc cagccaaaat tacaatggtc ttaattgcag tagcagcatc
    23341 tattggtggt gtaggtattg ccttgttaac tgaaaattat gtcaaaaaag acatgaaagc
    23401 agctgctcgt ttaatcatta acaacattga aatgttagtg atgtttttgt tacctgctct
    23461 tactggggca attattttag caagacctct atattctgtt ttttacggag ctagcgagga
    23521 gcgtgccatt cacctctttg tggcggttct ctttcaaacc ttgctactgg cgctttacac
    23581 cctcttttca ccgatgcttc aagctctttt tgaaaatcga aaagcgattt actactttgc
    23641 ctatggtatc ttgattaagt tagttttaca gataccgctt atttatttgc tacatgctta
    23701 tggtccttta ctagcgacga cgattgcttt agtggtgccg atttatttga tgtatcgacg
    23761 cctatatcag gttactcatt ttaaccgcaa actgttgcaa aaacgtttat tattaacctt
    23821 aattgaaacc ttattaatgg gactggtcgt gtttgtggcc aactggctat tgggctatgc
    23881 ctttaaaccg acaggccgct tgaccagcct tctttacctc ctcattattg gtggcttggg
    23941 aatgacggtt tacacggcac tcaccttgct gacgcatcaa ctggataaat taattggtag
    24001 caaagctagt cgccttcgtc agaaattagg ctggcattaa tataatgaca ccaagaacga
    24061 tttcgtgagt gcttatcgaa atcgtttttt tcttaatgat ctcgcttagt aaaggtagct
    24121 gataaaaaat caggatttcc caagcaaact actgatattt ttggtataat gataaaagtg
    24181 taaaaaaata gaaggaagta tatcaacatg ggaaaatgtc aagttatttc gcatccgctt
    24241 atccaacaca aactttcaat cttacgtcgt caaaccacat caactaaaga ttttcgtgag
    24301 ttggttaatg aaattgcgat gctgatggga tatgaagtgt cacgcgacct tcccttagaa
    24361 gatgtcgaca tccaaacgcc agtctcaaaa acggtccaaa aacagttagc tggtaaaaaa
    24421 ttagctattg ttccgattct tcgtgctggt attgggatgg ttgatggctt gttaagtttg
    24481 gtaccagctg caaaagttgg ccatatcggc atgtaccgta atgaagaaac ccttgaacct
    24541 gttgaatacc tcgttaaact accagaagat attaaccaac gacaaatttt ccttgttgat
    24601 ccaatgttgg caacaggtgg ctcggctatc ttagcagtgg attcgttgaa aaaacgtggc
    24661 gcagcaaata ttaagtttgt ctgtttagtt gcagcaccag aaggggtgaa aaaacttcaa
    24721 gaagctcatc cagatattga tatcttcaca gcagcacttg atgatcattt aaatgaacat
    24781 ggctatatcg tgccaggatt gggcgatgct ggtgatcgtt tatttgggac aaaataaaag
    24841 agacaaccat caaatagtag cctttttagg ccaatcgttc ttgattttgt ttaaaaaatc
    24901 agagagattt ctcttcttta aaggaaaagc aagtttatga tttgaccttt attgaccaaa
    24961 atattataat aaagacaatc agtaaaaaag agatgaccta gtgggttgcc gtctctcaaa
    25021 atgacgctac taaaaaccct tgtagattgg agaatgtatt atgattcctg ttgttattga
    25081 acaaactagc cgtggagaac gttcttatga catttattca cgtttattaa aagaccgtat
    25141 tatcatgtta acagggcctg tcgaagacaa catggccaac tctgtcatag cgcagctctt
    25201 attccttgac gcgcaagaca acactaaaga tatctaccta tatgtcaaca caccaggtgg
    25261 ctctgtctca gcaggcttgg ctattgtcga taccatgaac tttatcaagg ccgatgtgca
    25321 aactattgtc atgggtatgg cagcttctat ggggacagtc attgcttcat caggaacaaa
    25381 aggcaaacgc tttatgttac caaatgcaga gtatatgatc caccagccaa tgggtggtac
    25441 aggtggtggc acgcaacaaa cggatatggc tatcgcagca gaacatctct taaaaacacg
    25501 tcaccgttta gaaaaaatct tagcgcaaaa tgctggaaaa acgattaaac aaatccataa
    25561 agatgctgag cgtgattatt ggatgagtgc tgaagaaacc ttggcttacg gtttcattga
    25621 tgaaatcatg gaaaacaacg aactaaaata aagaggatct ctgcaaaagt attctagaaa
    25681 cttctaggat gctttttctc ttagaaagga aaataatgat acagcctact gcattaaaac
    25741 agcttcaaga gttaaaacgt cagttcagat ccctttgcaa ccaattatga gatagtttga
    25801 ggatgatcct tagcagctgt gtgcaagaag ttatgacgat ttcataaagg atgacctagc
    25861 cagtctttct tcgtctcttt tacttaaagt gtggtataat cagattatgc tagccaaaac
    25921 taaaaaaggc attgccatta aaggtgttgt agatcggctt atcctagatc tcataacaat
    25981 gctgtagtac cacccttacc ttgctactaa aggcgctgtt gaagcacaaa ttgacttgca
    26041 aaggatcttg actgataata tgtccggtgg aatcgccaaa gcagcaaaaa gaccaagacc
    26101 cttatttggt ctctaccaaa atataataga aaaggattta gaatgtttca aaaacaagaa
    26161 cgtattggac tcgtcgttta cctgtattat aaccgagatg ccagaaagtt atcaaaattt
    26221 ggtgatttat attaccattc caagcgctct cgttacctca ttatttatat taataaaaat
    26281 gatttagaca caaaattaga agaaatgaga cgtttgaaat gtgttaaaga cattagacca
    26341 tcagcttttg atgatattga ccgccaattt gtaggtaacc ttcatcgcga cgaaacaaac
    26401 aaccatcaaa agggttaaca accccctagt tactgattag cgtttcagat ttagttagct
    26461 tattaaagta agaaggtttt gacagatgct cacactactt caagacaatg agacaactag
    26521 agcattagtg aataactgag ttgactgtca cttctttaat aagaacggat aggattggtc
    26581 ctaaaataga gcactgcaaa gatatgccag tgctttttag ctcatttttt gataaaatag
    26641 aactactaaa aagtgaagga aataagatga tcacaggaaa actcataacc gttgaaggtc
    26701 cagatggcgc agggaaaacg actgttttag agcaactcat tccactgtta aaacaaaaag
    26761 tggctcagga tatcttgaca acaagagagc ctggaggtgt tgccatttca gaacacatta
    26821 gagaacttat tttagacatc aaccatactg ctatggaccc taaaacagaa ctcttacttt
    26881 atattgcggc tcgaaggcag catttggtgg aaaaggtact accagctctt gaagcaggcc
    26941 agttggtttt tattgatcgt ttcatcgata gttcagtagc ttatcaaggt gcgggacgcg
    27001 gtttgatcaa agcagacatt cagtggctca acgagttcgc aacagatggt ttagagcctg
    27061 acttgaccct ttattttgat gttccttctg aaattggttt agcacggatt aacgcgaacc
    27121 aacaaagaga agtcaatcgt ttagatttgg aaacaataga gatacatcaa cgagtacgaa
    27181 aaggatacct agccttagct aaggagcatc caaaacgtat tgtcacaatt gatgcgacta
    27241 aaccattgaa agaagttgtc tctgtcgctt tggaacatgt cttagccttg cttttagcct
    27301 aggataaggg agggtaggaa tggatttagc gcaaaaagct cctaacgttt atcaagcttt
    27361 tcagacaatt ttaaagaaag accgtctgaa tcatgcttat cttttttcgg gtgattttgc
    27421 taatgaagaa atggctcttt ttttagctaa ggtcatcttt tgtgaacaga aaaaggatca
    27481 gacgccctgc gggcattgtc gctcttgtca attgattgaa caaggagatt ttgccgatgt
    27541 gacggtattg gaaccaacag ggcaagtgat taaaacggat gtggtcaaag aaatgatggc
    27601 taacttttct cagacaggat atgaaaacaa acgacaagtt tttattatca aagattgtga
    27661 caaaatgcat atcaatgccg ctaatagctt gctaaaatac attgaggagc ctcagggaga
    27721 agcttacata tttttattga ccaatgatga taacaaagtg cttccgacca ttaaaagtcg
    27781 gacacaggtt tttcagtttc ctaaaaacga agcctatctt taccaattgg cacaagaaaa
    27841 gggattatta aaccatcagg ctaagctagt agccaaactt gccacaaaca ccagtcatct
    27901 agaacgtctg ttgcaaacga gcaagctttt agaactgata actcaagcag agcgttttgt
    27961 atctatttgg ctgaaagatc agttgcaggc atatttagcg ttgaaccgtc tggtacagtt
    28021 agcaactgaa aaagaagaac aagatttagt tttgaccctt ttgaccttgc tcttggcaag
    28081 agagcgtgcg caaacgcctt tgacacaatt ggaggctgtc tatcaggcta ggctcatgtg
    28141 gcagagcaat gttaattttc aaaacacatt agaatatatg gtgatgtcag aataagtgca
    28201 attggaattc gttatgggga aacgaagctt gtcaaaagac ttgcccgtag cgaccaaagt
    28261 agcggcgcat aagggcaaaa aagcttttga agaaaatact gcctttgcaa cagatttgat
    28321 gaaagaagta tcacgattaa taacacaaaa tcaacttgaa atgacgtttg ttaatagtgt
    28381 ctttctctta gatcagcatg ttgtcctaat tcccttttca gcagaagagc acatggattt
    28441 ttacaactgt taaaagattt agcggtcgat tttaggtcaa gaagtgagct gccccagatt
    28501 aacagccaag aagatttcat tttctatgga ggctatggac cgtgtggcag gccactgtgc
    28561 tgctttcgtt tttgggaaaa tttctgacag tatctattaa aatactaaaa agtcaagggt
    28621 tatcattgac tttgggtaaa gcaacaagcc cttatggccg tttgctttgc tgtctctatg
    28681 atgaaggtgt cttttaccaa taaagcaaga aaaaattccc tgaatatggt accatagtag
    28741 agacaagtga tggccctgca acagtagcag ccgttgatat atttacagat cccattaagg
    28801 tgcggttaaa agaccagttg accttagtca cttatgcttt agaggaggtt aaagtaggtg
    28861 aataaaaaag aattattcga tgcttttgat ggattttccc aaaatttaat ggttacttta
    28921 gctgaaattg aagccatgaa aaaacaagtc caatcactag tagaagaaaa cacgattctt
    28981 cgcctagaaa atacaaaact acgggaacgt ttgagtcacc tagaacatga aacggtagct
    29041 aaaaatcctt ccaaacaaag gaaggatcac ttagagggaa tttatgatga agggtttcat
    29101 atctgcaatt ttttctatgg acaacgtcgt gaaaatgatg aagaatgtat gttttgcaga
    29161 gaattattag atagaaagta agggcatgca ggttcaaaaa agttttaaag acaaaaaaac
    29221 aagcggaacc ttgtatttgg ttccaacccc aattggcaat ctgcaggaca tgacctttag
    29281 agcagtggca acgttaaaag aggttgattt tatttgtgca gaagacacaa gaaacacagg
    29341 tcttttgcta aaacactttg atattgctac caagcaaatc agctttcatg agcacaacgc
    29401 ctatgagaag attcctgatt taattgattt attaatatca ggacggtcac tagctcaggt
    29461 gtctgatgca ggaatgccat cgatttctga tcctgggcat gatttggtca aggctgctat
    29521 tgatagtgat atcgcagtcg ttgctttacc aggtgcctca gcagggatta cagctttgat
    29581 tgctagtgga ctggctcctc aaccccatgt tttttatggg tttttaccca gaaaagcagg
    29641 gcaacaaaag gctttctttg aggacaaaca ccattaccca gagacacaaa tgttttatga
    29701 atcaccctat cgcatcaaag ataccctgac caatatgttg gcttgttatg gtgatcgtca
    29761 agtggtgctt gtcagagaat taaccaagct ttttgaggag taccaacggg ggtcgatttc
    29821 agaaatcttg tcctaccttg aggaaacacc cctcaaaggg gagtgtctgc tgattgtggc
    29881 tggagcccaa gcagacagtg aggttgagct gacagctgat gttgacttag tgtctctagt
    29941 gcaaaaagaa attcaagcag gagccaagcc aaatcaggct attaaaacaa ttgctaaagc
    30001 ttaccaggta aatcgccaag agctttacca acaatttcat gacttataag tcatcgtaga
    30061 ttaggagaaa aacaaatgac agaagatcaa gcaactatcc ttattttagg agtatacgga
    30121 atcatattgg ctgtattctt attatcagct ttattatgcc ttatcgctaa ctggcgactc
    30181 tttaaaagag caggttacaa aggatggtat agtctcattc ctttctatgc aggttttgtc
    30241 aaacacaaaa tcacttttgg agaagataat aaatggtttt actttattgg ttgggtcatt
    30301 gctatttatt attactatgt gcacttttgc tatgtccgtg cttttggtgg atcaaagggt
    30361 ctagcagtat ttggcttgtt tttcccaggc attgcttctt tgatagtggc ttttggaaaa
    30421 acttatacca cacaagaatg ccaccctgtg ccacatcttt taaactaaga gaaaaaagac
    30481 catcaattgg atttattgat ggtcttttag gtgtttaaat gattttagtc ccgtgaacaa
    30541 tggccgttcc agtgagttga ctcaagcttt ggcaattctc agcagtgatg cctcccccaa
    30601 tcatgatttc aatgcgttta ttggcatagg tcacaagact tttaagctgt tccacattgt
    30661 ctgtaatagg agtagcttca ggtgagccat gagttagcac acgcacaaag ccataatcaa
    30721 tcagttggtc aagcgcttgg tgctggtgat cagtcggaat ccggtcaaaa gccatgtgga
    30781 aaaccagtgg caagccttgt gtagcaggca gtaattgctc gatagcgtcg gtatccagtt
    30841 gattttctgt ggtcagcaag cctaagacta gcgcatctga gccagcttca acagctttta
    30901 agatatcttc ttccatagct tttagttcga ggtcgttata gacaaaatcg ccaccgcgag
    30961 gtcgaatcat ggtcgctacg ctaatctttt tatcgtgtaa gagctgacag gcttctttga
    31021 tgacgccata agatggcgtg gtccctccga cagctaggtt atcacagagt tccacacgac
    31081 tgatttgacc agcatcaagg gttggcagta gtgtgaggtt ctcagcacaa aattctttaa
    31141 tcatttttag atctccttta tcagtaatat tatagcacga atgaagctag tcatcaggaa
    31201 acatttttgt caaatcatgg acattatgct atactcacta gtattaaaag taggccaaaa
    31261 cagcagcaaa tactttgaaa aaagattgct atgttctacg gcaatatcag tctttaccaa
    31321 cgaactctca agaagaaaag aaagacaaag cttagcattt taaaaaagcc cccttttttt
    31381 tgtgaaatga tgaccaaaaa caggcgcctc acgcctaaaa cagttacact aaaggagaac
    31441 aaatgattac gatttaccaa tacccaaaat gtagcacctg ccaaagagcc atggctgaat
    31501 taaagcaact ggttagtgac tttgaagcca ttgacatcaa agctaatcca cccaaagctc
    31561 aggacctcaa acattggatg gaaacatctg gttataccat caaaaatttc tttaatacca
    31621 gtggtaacag ctaccgcgaa ttgggactta aagataaaat agaccagctt agccttgata
    31681 aagctgctga acttttagcc acagatggta tgttgattaa acggcctatt ctgattaagg
    31741 acggtaacgt cttacaagtt ggctatcgca agccatatca agagttggat ttaggataat
    31801 gcgacaaagt ctcaaaaaag gacaaggcaa cattataacg ccttgtcctt ttttgggatc
    31861 tgtttttaga aattagagat caatatctag taaaattggc gtatggtctt ggcgttcccc
    31921 agaagaaatc atttcagaac gcttaacctt atccacaagt cggtttgaag ctagccaata
    31981 gtcaattctc caaccggtat tattgatttt gctggttttg ctacgttgtg cccaccaggt
    32041 ataaacatga ggaatatcgc cgtgcacgtg acgaaaagta tctgtaaagc ctcttgctaa
    32101 taggttagta aagccttgac gttcttcgtc ggtaaaacca ggagaacgtc gattgctgtt
    32161 tggatttgcc aaatcaatct ctttatgggc aacattgtaa tctcccgtag ccaaaacagg
    32221 cttttgagca tccagttcag tcaaataatc agcgtatttg tggtcccaaa tttgacggtc
    32281 atctaaacgt ctaaggccat caccagcatt aggcgtgtaa acctgtgtga cgaaaaagtc
    32341 ttcaaattct agggtaatga tacggccctc agcatccatt gttgttgggg caccaatttc
    32401 tggaaaagta atgacagggt ttaacgtgtt tttgtacagg aacatggtgc cagcatagcc
    32461 tttcctagca ggctcaactg aagaacgcca cacatgcaaa tagtttggaa agtaactaag
    32521 tagggtctcg atatgttttt tggtaggccc cttagcagat aatttagttt cttggatggc
    32581 aataatatcc gcatcttgag cgactaaagt gtctaaaaca gcgcgtgata aaagcgcacg
    32641 aggggactct cctgtgagag cagcatttaa ggaatcaatg ttccatgaaa tcagtttcat
    32701 ttggtttctc tttctaacag atagtcttgt tgttattgta acaaaaaacg aaacgataag
    32761 cgactttggg cacctagccc ccataaaaca gtctagccaa atgaagcata gcagcgtaag
    32821 aacaagacaa ggaggtgatc agtgagcata tcgtttgaca gttaagagta ggattactat
    32881 aatagaagca taaatgtaag cgctaacaaa ataaaaaata taggagaatg tcaatggcac
    32941 aaaaaacagt catcaccgaa gaaacaaccg attttgttat ggatttcaaa acaagtagcg
    33001 ctgagggaaa tgttgatttt attaacgttt ttgaccttga gaaaatggca caacaggtca
    33061 tccctaaagg agcctttggt tatattgcta gtggtgctgg tgataccttt accctccatg
    33121 aaaatattcg ctcatttaat cataaattaa ttgtccctca ctccctcaaa ggggttgaaa
    33181 atccgtcaac agagattacg tttgatggtg attacttaac ctctcctctt attttagcac
    33241 ctgtagcggc tcataaactg gccaatgaac aaggagaagt agcgtctgct aaaggattga
    33301 aggaatttgg aagtatctac accactagtt cctactcaac aactgacctg ccagaaatca
    33361 gtgctgcctt aggtgggaca ccccattggt ttcaatttta ttacagtaaa gacgatggca
    33421 ttaatcgtaa tattatggat cgtgtcaaag cacaaggttg caaagctatc gttttgacag
    33481 cagatgcaac agttggagga aaccgcgaag ttgataggcg aaacggtttt gtttttccgg
    33541 tcggtatgcc aattgttcaa gaatatttac ctgatggtgc aggtaaaaca atggattatg
    33601 tctataaatc agctaaacaa gcgcttacct caaaagatat tgaatatatc gcaacttact
    33661 caggcctgcc tgtttatgtc aaaggaccac agtgtgctga ggataccttg cgggcattgg
    33721 acgcaggagc atcaggtatc tgggtaacca atcatggtgg ccgtcaatta gatggtggtc
    33781 cagctgcttt tgattcctta caagaagtcg ctgaagcagt tgatcaaaaa gttcctattg
    33841 tctttgactc aggtataaga cggggtcaac atattttcaa agctcttgct tcaggtgctg
    33901 accttgttgc cttggggcgt ccagcgattt acggcttggc tatgggagga agcattggta
    33961 ctcgtcaggt ctttgaaaag ttaaatgacg agttaaaaat ggttatgcaa ctggctggga
    34021 cacaaactat ccaagatgtt aaagccttta accttcgcca caatccgtat gattcatcga
    34081 ttccatttga tcaaaatgcg ctacgcttag attagaacag acaaaaacct ccgctatcat
    34141 gtcacaaata gtagaggttt tacactgcaa aaagaggtat gaaaatccaa taacatagtt
    34201 acaaggtttt cgtttacccc ccactaatag attaaaatga aagacttctt acattaatag
    34261 aaatttctgt tgcttttctc agaaaaatgt ggttaaataa tcaaatatta ttaacgaaaa
    34321 atgagttaat gattaacatt aaactggttt tagttaaaac atttaggagg gtatcaggtg
    34381 gagaaaaagc aacgtttttc ccttagaaaa tacaaatcag gaacgttttc ggtcttaata
    34441 ggaagcgttt tcttggtgat gacaacaaca gtagcagcag atgagctaag cacaatgagc
    34501 gaaccaacaa tcacgaatca cgctcaacaa caagcgcaac atctcaccaa tacagagttg
    34561 agctcagctg aatcaaaatc tcaagacaca tcacaaatca ctctcaagac aaatcgtgaa
    34621 aaagagcaat cacaagatct agtctctgag ccaaccacaa ctgagctagc tgacacagat
    34681 gcagcatcaa tggctaatac aggttctgat gcgactcaaa aaagcgcttc tttaccgcca
    34741 gtcaatacag atgttcacga ttgggtaaaa accaaaggag cttgggacaa gggatacaaa
    34801 ggacaaggca aggttgtcgc agttattgac acagggatcg atccggccca tcaaagcatg
    34861 cgcatcagtg atgtatcaac tgctaaagta aaatcaaaag aagacatgct agcacgccaa
    34921 aaagccgccg gtattaatta tgggagttgg ataaatgata aagttgtttt tgcacataat
    34981 tatgtggaaa atagcgataa tatcaaagaa aatcaattcg aggattttga tgaggactgg
    35041 gaaaactttg agtttgatgc agaggcagag ccaaaagcca tcaaaaaaca caagatctat
    35101 cgtccccaat caacccaggt accgaaagaa actgttatca aaacagaaga aacagatggt
    35161 tcacatgata ttgactggac acaaacagac gatgacacca aatacgagtc acacggtatg
    35221 catgtgacag gtattgtagc cggtaatagc aaagaagccg ctgctactgg agaacgcttt
    35281 ttaggaattg caccagaggc ccaagtcatg ttcatgcgtg tttttgccaa cgacatcatg
    35341 ggatcagctg aatcactctt tatcaaagct atcgaagatg ccgtggcttt aggagcagat
    35401 gtgatcaacc tgagtcttgg aaccgctaat ggggcacagc ttagtggcag caagcctcta
    35461 atggaagcaa ttgaaaaagc taaaaaagcc ggtgtatcag ttgttgtagc agcaggaaat
    35521 gagcgcgtct atggatctga ccatgatgat ccattggcga caaatccaga ctatggtttg
    35581 gtcggttctc cctcaacagg tcgaacacca acatcagtgg cagctataaa cagtaagtgg
    35641 gtgattcaac gtctaatgac ggtcaaagaa ttagaaaacc gtgccgattt aaaccatggt
    35701 aaagccatct attcagagtc tgtcgacttt aaagacataa aagatagcct aggttatgat
    35761 aaatcgcatc aatttgctta tgtcaaagag tcaactgatg cgggttataa cgcacaagac
    35821 gttaaaggta aaattgcttt aattgaacgt gatcccaata aaacctatga cgaaatgatt
    35881 gctttggcta agaaacatgg agctctggga gtacttattt ttaataacaa gcctggtcaa
    35941 tcaaaccgct caatgcgtct aacagctaat gggatgggga taccatctgc tttcatatcg
    36001 cacgaatttg gtaaggccat gtcccaatta aatggcaatg gtacaggaag tttagagttt
    36061 gacagtgtgg tctcaaaagc accgagtcaa aaaggcaatg aaatgaatca tttttcaaat
    36121 tggggcctaa cttctgatgg ctatttaaaa cctgacatta ctgcaccagg tggcgatatc
    36181 tattctacct ataacgataa ccactatggt agccaaacag gaacaagtat ggcctctcct
    36241 cagattgctg gcgccagcct tttggtcaaa caatacctag aaaagactca gccaaacttg
    36301 ccaaaagaaa aaattgctga tatcgttaag aacctattga tgagcaatgc tcaaattcat
    36361 gttaatccag agacaaaaac gaccacctca ccgcgtcagc aaggggcagg attacttaat
    36421 attgacggag ctgtcactag cggcctttat gtgacaggaa aagacaacta tggcagtata
    36481 tcattaggca acatcacaga tacgatgacg tttgatgtga ctgttcacaa cctaagcaat
    36541 aaagacaaaa cattacgtta tgacacagaa ctgctaacag atcatgtaga cccacaaaag
    36601 ggccgcttca ctttgacttc tcactcctta aaaacgtacc aaggaggaga agttacagtc
    36661 ccagccaatg gaaaagtgac tgtaagggtt accatggatg tctcacagtt cacaaaagag
    36721 ctaacaaaac agatgccaaa tggttactat ctagaaggtt ttgtccgctt tagagatagt
    36781 caagatgacc aactaaatag agtaaacatt ccttttgttg gttttaaagg gcaatttgaa
    36841 aacttagcag ttgcagaaga gtccatttac agattaaaat ctcaaggcaa aactggtttt
    36901 tactttgatg aatcaggtcc aaaagacgat atctatgtcg gtaaacactt tacaggactt
    36961 gtcactcttg gttcagagac caatgtgtca accaaaacga tttctgacaa tggtctacac
    37021 acacttggca cctttaaaaa tgcagatggc aaatttatct tagaaaaaaa tgcccaagga
    37081 aaccctgtct tagccatttc tccaaatggt gacaacaacc aagattttgc agccttcaaa
    37141 ggtgttttct tgagaaaata tcaaggctta aaagcaagtg tctaccatgc tagtgacaag
    37201 gaacacaaaa atccactgtg ggtcagccca gaaagcttta aaggagataa aaactttaat
    37261 agtgacatta gatttgcaaa atcaacgacc ctgttaggca cagcattttc tggaaaatcg
    37321 ttaacaggag ctgaattacc agatgggcat tatcattatg tggtgtctta ttacccagat
    37381 gtggtcggtg ccaaacgtca agaaatgaca tttgacatga ttttagaccg acaaaaaccg
    37441 gtactatcac aagcaacatt tgatcctgaa acaaaccgat tcaaaccaga acccctaaaa
    37501 gaccgtggat tagctggtgt tcgcaaagac agtgcctttt atctagaaag aaaagacaac
    37561 aagccttata cagttacgat aaacgatagc tacaaatatg tctcagtaga agacaataaa
    37621 acatttgtgg agcgacaagc tgatggcagc tttatcttgc cgcttgataa agcaaaatta
    37681 ggggatttct attacatggt cgaggatttt gcagggaacg tggccatcgc taagttagga
    37741 gatcacttac cacaaacatt aggtaaaaca ccaattaaac ttaagcttac agacggtaat
    37801 tatcagacca aagaaacgct taaagataat cttgaaatga cacagtctga cacaggtcta
    37861 gtcacaaatc aagcccagct agcagtggtg caccgcaatc agccgcaaag ccagctaaca
    37921 aagatgaatc aggatttctt tatctcacca aacgaagatg ggaataaaga ctttgtggcc
    37981 tttaaaggct tgaaaaataa cgtgtataat gacttaacgg ttaacgtata cgctaaagat
    38041 gaccaccaaa aacaaacccc tatctggtct agtcaagcag gcgctagtgt atccgctatt
    38101 gaaagtacag cctggtatgg cataacagcc cgaggaagca aggtgatgcc aggtgattat
    38161 cagtatgttg tgacctatcg tgacgaacat ggtaaagaac atcaaaagca gtacaccata
    38221 tctgtgaatg acaaaaaacc aatgatcact cagggacgtt ttgataccat taatggcgtt
    38281 gaccacttta ctcctgacaa gacaaaagcc cttggctcat caggcattgt ccgcgaagaa
    38341 gtcttttact tggccaagaa aaatggccgt aaatttgatg tgacagaagg taaagatggt
    38401 atcacagtta gtgacaataa ggtgtatatc cctaaaaatc cagatggttc ttacaccatt
    38461 tcaaaaagag atggtgtcac actgtcagat tattactacc ttgtcgaaga tagagctggt
    38521 aatgtgtctt ttgctacctt gcgtgaccta aaagcggtcg gaaaagacaa agcagtagtc
    38581 aattttggat tagacttacc ggtccctgaa gacaaacaaa tagtgaactt tacctacctt
    38641 gtgcgggatg cagatggtaa accgattgaa aacctagagt attataataa ctcaggtaac
    38701 agtcttatct tgccatacgg caaatacacg gtcgaattgt tgacctatga caccaatgca
    38761 gccaaactag agtcagataa aatcgtttcc tttaccttgt cagctgataa caacttccaa
    38821 caagttacct ttaagataac gatgttagca acttctcaaa taactgccca ctttgatcat
    38881 cttttgccag aaggcagtcg cgttagcctt aaaacagctc aagatcagct aatcccgctt
    38941 gaacagtcct tgtatgtgcc taaagcttat ggcaaaaccg ttcaagaagg cacttacgaa
    39001 gttgttgtca gcctgcctaa aggctaccgt atcgaaggca acacaaaggt gaatacccta
    39061 ccaaatgaag tgcacgaact atcattacgc cttgtcaaag taggagatgc ctcagattca
    39121 actggtgatc ataaggttat gtcaaaaaat aattcacagg ctttgacagc ctctgccaca
    39181 ccaaccaagt caacgacctc agcaacagca aaagccctac catcaacggg tgaaaaaatg
    39241 ggtctcaagt tgcgcatagt aggtcttgtg ttactcggac ttacttgcgt ctttagccga
    39301 aaaaaatcaa ccaaagattg ataacaaagc gcaaagagac aacaaatcat cccttttaac
    39361 agtctgacct ttctttgaga ttgagctggc agatgatcat ttcttaacaa aagttaaaga
    39421 gttgagcaaa gtaaggaaca gacataaaga ccataaaagc aagccagttt ggcttgcttt
    39481 tatggtgtta ttgtcgtgtg ctacgatgac taaaaaagaa caacgaacaa tgacctcgaa
    39541 tcaccaaaag gacttgattt gatagcttcc ctatgctata ctaagcctat tctttcaaga
    39601 aggactcctt ttgtggaaaa gactgaaaaa aaggacacta atctatccaa aaactccaga
    39661 tgagtagctg caaacgatgc ctttgctgtg atcaaggtgg taaagcagac tgacttgtca
    39721 ctatctgagc aggtgtcaaa aaaagaagct ttggctttgt cattcaacat actgagcttc
    39781 agtctttcag aacggagaca cccccagttt tgtactcaaa aagcataaac agctctgctg
    39841 atgtgacatc tgatttctac gtgcgcagtg agccaaaaca gctgctgttt gctatggaaa
    39901 aagtggcgcc aatcgagatt tttgagaccc taggctcaaa aataaggcat agaattccaa
    39961 aggaagtcgc tgccgtgagc acaacctaag aaaaactatc ccaaaagact ttttctgcaa
    40021 tttgaaatac tgaatttcag tattttttct tttgtaacta agagcaatga atgaggtaaa
    40081 aaaaggcaac aatgtcaaaa aagaaacgaa aacactatca ggtttatgag ggattacgct
    40141 gtgctatgac gctttgtttt atcagtggct atgtcaatgc ctttacctat atgacccaag
    40201 gaaaacgttt tgcaggtgtt cagacaggca accttttgtc atttgccatt cgcttgtcag
    40261 aacagcaact gaaggaggca ctgcaatttt tacttcccat gatcgttttt atgcttgggc
    40321 agtcctttac ttatttcatg caccgctggg ccactaaaaa agggctccac tggtacttat
    40381 tatcaagtgt tatcttaaca gggattgctt ttggaacggc cctattcacg ccttttcttc
    40441 cttccaatgt tacggtagca gctttagcct tttttgcctc tattcaggtt gatacgttta
    40501 aaaccttacg aggagctagc tatgctaatg tgatgatgac aggaaatatc aaaaatgccg
    40561 cctatttact aaccaaaggc ttgtacgaaa aaaatcacga actaacacat atcggacgca
    40621 acaccttaat agtcatcttg gcttttgctg ttggggtggt ttgttcgacg ttgctttgca
    40681 tagcttatgg cgagtatgct ttgatgccta ttttaatgcc tttactctat gtcaattacc
    40741 tgttggctca ggaattttat cacattcaaa ccaaaatcaa accgattaaa agaacttaat
    40801 ggacttgtgg agaaagaaag ttcatttagg gtaagttttt actcaccctc ctttgattga
    40861 ctggttttgc tgccccttaa aatatgatat aatagaccat tgatagctgt tacttaacag
    40921 aaggctgata aaaaaggttc cattagcctt gagggttgaa tttaaacagg aaaaaacgaa
    40981 atcctacact atgcatctca atcgtacttt catttgagta tggttctgaa aggaaactat
    41041 gatgaaaaaa ccattttaca ttacgacacc catttattac ccatctggga aattacacat
    41101 tggttctgcc tatacaacta ttgcttgtga tgtcttggca cgctacaagc gcctgatggg
    41161 ccatgaggtc ttttacctca caggactaga tgaacacgga caaaagattc aaaccaaggc
    41221 aaaagaagct ggtattacac ctcaaaccta cgttgataac atggcaaagg atgtcaaagc
    41281 cctttggcaa ttgctagata tttcctatga cacatttatc cggacaacgg acgattacca
    41341 cgaagaggtc gttgctgctg tctttgaaaa attgctggcg caagatgaca tttaccttgg
    41401 cgaatactct ggttggtatt ctgtctctga tgaggaattt ttcactgaaa gccaattaaa
    41461 agaagtcttt agagatgaag acggtcaggt tattggaggg attgccccat caggtcatga
    41521 ggtcgagtgg gtctctgaag aatcctactt cctacgcctt agcaaatacg atgatcgtct
    41581 tgtggccttc tttaaagagc gacctgactt tatccaacca gatggtcgta tgaatgaaat
    41641 ggtgaaaaac tttatcgagc caggcctaga agatttggct gttagccgta ctacctttac
    41701 atggggtgta cctgttccat cagacccaaa acacgtggtt tatgtctgga tcgatgccct
    41761 cttaaactac gcgacagctc ttggttatcg tcaagctaat cacgctaact ttgataagtt
    41821 ttggaatgga acggttttcc acatggttgg aaaagatatc ttgcgttttc atagcatcta
    41881 ctggccaatt ttactcatga tgcttgattt accaatgcca gaccgcttaa ttgcccatgg
    41941 ttggtttgtc atgaaagacg gtaaaatgtc taaatcaaaa ggcaatgtgg tctatccaga
    42001 aatgttagtt gagcgctttg gacttgatcc tcttcgttat tacctcatgc gttctttgcc
    42061 agttggttca gacgggacct ttacccctga agattatgtg ggtcgtatca actatgagtt
    42121 agccaacgac cttggcaatt tattgaaccg taccgttgcc atgatcaaca agtattttga
    42181 cggcacggtg ccagcttatg ttgacaatgg aactgccttt gatgctgact taagtcaact
    42241 gattgatgct cagctagcag actaccataa gcacatggaa gcggtggact acccacgcgc
    42301 cttggaggct gtttggacca tcatcgctcg taccaacaaa tacatcgatg aaaccgctcc
    42361 ttgggtgctc gctaaagaag atggtgacaa agctcaacta gccagtgtca tggcacactt
    42421 agcagccagc ttgcgtctgg tcgctcatgt gatccaaccc tttatgatgg aaacatcagc
    42481 tgctatcatg gcccagcttg gtttggaacc tgtttctgat ttgtcaacac ttgctctagc
    42541 agattttcct gccaatacaa aggttgttgc caaagggaca ccgattttcc cacgtcttga
    42601 catggaagct gagattgact acatcaaagc ccaaatgggt gacagctcag ctatttccca
    42661 agaaaaagaa tgggtccctg aagaggttgc gctcaaatct gaaaaagacg tcatcacatt
    42721 tgaaaccttt gatgctgtgg aaatccgtgt ggcagaagtc aaggaagtgt caaaagtgga
    42781 aggttcagaa aaattgctgc gctttagagt agatgcagga gacgggcaag accgtcaaat
    42841 cttgtcaggt attgccaaat tttaccccaa cgaacaagaa ttagtgggta aaaaactaca
    42901 aattgttgct aacctgaaac cgcgtaaaat gatgaaaaaa tacatcagtc aagggatgat
    42961 tctatcagca gagcatggag atcagctaac ggtcttaacc gttgattcct ctgttccaaa
    43021 tggaagtatc attggctgat gctgacctat tattcaaaaa acctaagcaa gaacatgtgc
    43081 ttaggttttt ttgattgcct tcaagaaaga cgaataacga gatgggtgat atgacatcaa
    43141 aagcataact atcctaggac ctgtcctagt aagattgctg tgcttttgac aagtgaacag
    43201 agaggtctta aaactatatc ttgtcataaa aaagattgca aaacactata tcttgtgtta
    43261 ttatggtttt tataaaagtt aagcatactt aactttagcc aaacaaaaga ggacactaga
    43321 gcgtgtccca caagacagtt gagcccttcg cttttttagt agagtaggag tgctcaagtc
    43381 aaaaagagac atcccatcaa accattgctg tttagcaggt ctttttgtgt tgctcaaaaa
    43441 aacaattcct gtctgtttgg cgtctagtga tgacttaggc ttagcgctac tagacttttg
    43501 tttgaaaaat acctcaagcc ttgaaggaga caaatgaccc aacattatta tgaacgttcg
    43561 caatccccaa ttgaatacgc cctatctgaa acacaaaaac agttgcgctc catcaattgg
    43621 aattacctta atgatgacaa agatttagaa gtgtggaacc gtgtcactca aaatttttgg
    43681 ttgcctgaaa aggttcctgt ttctaatgat ttaaattctt ggcgctcctt gggtgaggat
    43741 tggcaacagc tcatcacaag gacctacact gggttgacct tactagatac agtacaagca
    43801 acggttggtg atgtggcaca aattcagcat tcacaaaccg accacgaaca agtcatctat
    43861 acgaactttg cctttatggt ggggattcat gcccgctctt acgggacgat tttttcgacc
    43921 ctttgcagca gcgagcaaat cgaagaagca catgaatggg tggtctcaac acagagcttg
    43981 caagaccgtg cccgtgtctt gattccttac tatacgggtg atgacccttt gaaatcaaaa
    44041 gtagcagcag ctatgatgcc aggatttttg ctgtatggcg gcttttacct tcctttttac
    44101 ctatcagcac gtggtaaaat gccaaacaca tctgatatca tccgcctgat tttacgcgac
    44161 aaagttattc acaactatta cagcggttac aaataccaac aaaaagtagc acgtcttagc
    44221 ccagaaaaac aggctgaaat gaaggccttt gtctttgact tgctctatga actcatcgac
    44281 cttgaaaaag cttacttgag agaactgtat gcaggctttg atttggcaga agatgctatc
    44341 cgttttagcc tttataacgc tggaaaattc cttcaaaatt taggctatga gtcgcccttc
    44401 acagatgaag aaacgcgcgt ttcaccagaa gtatttgctc agctatcagc gcgtgcagac
    44461 gaaaaccatg actttttctc aggcaatggc tcatcttatg tgatggggat caccgaagaa
    44521 accacagatg acgattggga gttttaagaa atggcagagc tgattattgt gtatttttca
    44581 tctaagtcca ataacaccca tcgcttcgtc caaaaattag gcctgcctgc tcagcgcata
    44641 ccagtagata ataggccact tgaagtttcc acccattacc ttttgattgt gcctacctat
    44701 gcagctggtg gctcagatgc caaaggagcc gtttctaaac aagtgattcg ttttttgaat
    44761 aatcctaaca atcgtaaaca ttgtaaggga gtgatttctt ctggaaatac caattttggc
    44821 gatacctttg ccttagcagg ccctatcatt tctcaaaaat tgcaggtccc cttattacac
    44881 caatttgaac tattaggcac tgctacagat gtcaaaaagg tacaggcgat ttttgcccgc
    44941 ttaaagcatc acacacacga caagcaaaaa caaaccaaca acctgattac agaaaggaca
    45001 cacccatgtc acaaaccaat gcgtcatacc tctcattaaa tgcactgacc cgttttaaaa
    45061 aaccagacgg cagctaccat tttgatagcg ataaagaagc tgttaggcgc tacctggaag
    45121 aacatgtctc tcccaatcaa atggctttta actcactaga agataagcta gcttacctca
    45181 tcaatgaagg gtattatgag caggccattt ttgatgccta tcctaatgac cttatcaagg
    45241 aggcctttca ttatgcctat caacaaggct atcgcttttt aaatctcatg ggcgctatga
    45301 aattttacca gtcctatgcc ttaaaaacct tggacggtaa gcagtatcta gaaacatttg
    45361 aagaccgtgc tgtgatgaat gcactctttt tagctgatgg agatcaaacc tttgtctttg
    45421 acgtgattga tgccatcttg caccgacgct ttcaaccagc taccccaacg tttttaaatg
    45481 ccggaaaaaa acgccgtggc gaatacattt cgtgctatct tcttcgtgtc gaagacaata
    45541 tggaatctat ctctcgcgcc attagcacca gcttgcaact ctcaaaaaga ggaggcggag
    45601 tcgccttgtg cctcaccaac ctcagagaaa tcggagcacc gataaaaggg attgaaaatc
    45661 aggcaacagg catcgttcct gtcatgaaac tactagagga ctctttttcc tatgccaatc
    45721 aactaggtca gcgccaagga gcaggtgcgg tttaccttca tgcccatcac cctgaggttt
    45781 tgaccttttt agacaccaaa cgtgaaaatg ccgatgagaa aattcgcatt aagtccctag
    45841 cattgggact tgtgatccca gatattacct tccagttagc caaagaaaac aaagacatgg
    45901 cactcttttc accctatgat atcaagcgtg cctatggcaa ggacatgtca gacatctcca
    45961 tcacagagga atacgataaa ctgctagcca atccagccat caaaaagacc tacatcagtg
    46021 ctagaaagtt ctttcagtta attgcagagc tacattttga gtcaggctac ccttacctct
    46081 tgtttgatga cacggtcaat aagcgcaacc ctcatgccaa aaaaggcaga atcgtcatgt
    46141 ctaacctgtg ttctgaaatc gctcaagtta gcaccccaag cactttcaaa gaagatttga
    46201 gttttgaaac cattggagag gatatctgct gtaatttagg gtctatcaat attgcccagg
    46261 ctatggcaga tgcgccacac tttgaacagc tcatcacaac gagcatcaga gcacttgatc
    46321 gtgtctctag agtgtctgac ctgaattgtg cgccttctgt tgagacaggc aatgcagcca
    46381 accatgcagt aggattaggc gccatgaacc tacatggttt tttggcaacc aaccacatct
    46441 actatgatac aaaagaagcc gttgacttta cagatctgtt tttccatgcc atggcctatt
    46501 atgcttttaa agcctcttgc caattagcca aagaaaaagg cgcttttgca ggattttcgt
    46561 tatcaaccta ttcagatggc acttattttg ccaagtattt gcaagaagat gccaagccac
    46621 aaacagccaa ggttgccaca ttgttgcaag attacggctt cacgttgcca acggtggcgg
    46681 attggcaagc cctagtagca gatatcaagc agtttggcct agccaatgcg cacttgctag
    46741 cggttgctcc gacaggctcc atcagctact tatcatcctg cactccgagt ctacaaccag
    46801 tcgttgctcc tgttgaggtc cgaaaagaag gtagcctggg caggatttac gtccctgcct
    46861 atcagattga ccaggctaac tatgcttact atgaacgtgg tgcctatgag gtcggcccaa
    46921 aagccatcat cgacgttgta gctgctgccc aaaaacacgt tgaccaagcc atctcattga
    46981 ccctgtttat gaccgatcaa gcgaccacac gtgacctgaa ccgctcctat atccaagctt
    47041 ttaagcaaaa ttgtgcatcg atctattatg tgcgagtgag gcaagacgtc ctagcaggca
    47101 gcgaacagta tgacgaggat agtcttgtga cagctcctgg agctagtgat gagaccacca
    47161 cagagtgtca aagctgtatg atctaacagc tactagaaag ctctcgtgtc ctatcacatg
    47221 cataggatca gtgcactcga cctttcaaga caagcaagca tcagctcttg cttgtctttt
    47281 tttggcctca aagcccgtta gtctgctgct atgcgaggct tttttgagca tcagaacgtc
    47341 aaaaaaaagg acatggagtc ctttttttgg cgatcggtgt tgaggccgtc acaaactgcc
    47401 cttgaaatac gcttctatgt ggagcttttt ttggtcctgt gacacgtaag ctccaacgac
    47461 ctccagctga cagcctcttg gaaacaagag ctcaacctct gaaggcacag ccgaataagg
    47521 ctcgacaaag gctgccttgg cccctttttt gacacagatg cgcacctcca ccggtcgatg
    47581 ggtcatggcg ccgtttttca aggctgtcgt gctcataaaa ctgtgcttgg tgtagcgtgt
    47641 accaagcttg atcttacaaa ggatatgagg gtcaaactga tggttacggt agtaagacgt
    47701 gagatcagca tgtgaaacac cgatatcacg caaaaacgtc tcgtatacat agcggtatac
    47761 tacaatgttc cacgggatga ctagccggtg agtcgcagca tcgagctggg ccacctgatc
    47821 ccttagctca ggcgtgagtt ggctgagctc acctttggct ttgtctaggc tggtgttgat
    47881 agggcctgcc tgctgacagg tataagcagc catcgcctct tgctcagccc ttgggtagat
    47941 gagacccttg ccccatcgct ttttaatcag tgtctcagcg cccttttgat ccgaaaaggt
    48001 aaaataagca ggcgtcccct cacaaaccgc ccgctcatag tgctcacaga caaaaagctc
    48061 gaccaagccc tcagtttgcc agatcagact aaaacagcta agaagaagga caatagccag
    48121 ttgatagcgc ttttttagca tagttccccc tgacaccagc ccaaaaggct gacccttccc
    48181 ctagaccttt tggctagctc ttgacaccac cagtttctca gacaggctaa tctttttgtc
    48241 atctctttct ccctaaacag actctcttat catgatatta tgctattatg agcgatttgt
    48301 caatccatag caaccgtttt ttagttagat aagtaagctt ttgacctaga ggcagacaag
    48361 agtggcagta cctcccgttt gctgtggtgg ctaataagga ctaacacaaa atctcaaacg
    48421 ctttcaaaaa cagctcctaa gcttaaaaaa gctgatgaac agatttgttg aacttaagag
    48481 agattgccat gattttctaa tcatttgatg tttaaaatga taaaaacatg aacttgaaat
    48541 gaaataatga gaggagtaaa ctagaaccat atcaaaaaat aatgaaatgg agtggtttta
    48601 tgaaaacaaa atcaaaacgc tttttaaacc tagcaaccct ttgcttggcc ctactaggaa
    48661 caactttgct aatggcacat cccgtacagg cggaggtgat atcaaaaaga gactatatga
    48721 ctcgcttcgg gttaggcgat ttagaagatg attcagctaa ctatccttca aatttagaag
    48781 ctagatataa aggatattta gagggatatg aaaaaggctt aaaaggagat gatatacccg
    48841 aacggcccaa gattcaggtt cctgaggatg ttcagccatc tgaccatggc gactatagag
    48901 atggttatga ggaaggattt ggagaaggac aacataaacg tgatccatta gaaacagaag
    48961 cagaagatga ttctcaagga ggacgtcaag aaggacgtca agaaggacgt caaggacatc
    49021 aagaaggagc agattctagt gatttgaacg ttgaagaaag cgacggtttg tctgttattg
    49081 atgaagtagt tggagtaatt tatcaagcat ttagtactat ttggacatac ttaagcggtt
    49141 tgttctaaaa aatatttttt atagtacaat tttttagcaa attgttttga aaaagaacac
    49201 tttataaata gttcatattt atggtataat acctaattca agtattttta aatggttggt
    49261 gaattcttgg ctgataaaat tctttattag tgttgagcag tcccactgtt ttaaaacaat
    49321 tttctgctat aattgggata atccctttag tagtcaggcc acctctgata ggggtggctt
    49381 ttttgggttt tagtgacccg tgtgttgaga aaggagcatt tatgccagaa aagaaagtgt
    49441 tgcccgtcct aagcatagtg gtgagttttg tctgcctgct tgatcatatc ttcttttttg
    49501 ctacttatag ttatctctac ttaccgcttg tagcaagtag tctagctctt atcggtctgg
    49561 tgcaaaacaa aggcaggcaa aaggtgtggt cgctagctgg actcgtccta gctgctctag
    49621 ccgtggcagt agtggcctat gcctactatg acccaaccgt catcccctac taaccttaac
    49681 cactccttcg cacgcaatca acagcacaaa aagcacccct gacaggtgct ttttgtgctt
    49741 tagccaacct atagcctcgt aatccctcac tgaaacagtc ccttaaagtt ccaccactga
    49801 tcttggatgc tctcacttaa ccgctgatgc caaggtttat ggtcttcttc tcttatctgc
    49861 tttagcatgc tttcttctag ctgtttttgt tgcttttcct cttccttttt ttgaagtgct
    49921 tcttcagctt ctttttcttt ttttatagta tcagagtctc tatagatata gctaccgaca
    49981 taaaatccgt cttctccttt aaatgagaaa gttaattttt ctcctttctt caaaggatct
    50041 tctcctaagt taagaatata aggtactcct gtataatatt gacgataagg atctgttttt
    50101 gttatatttt tttcgagaat aggactagct aaaattcctc gttctttact gttatgatca
    50161 cattgtctgt aaagatatac ccaccatcct tgagggatat atatttttac tactttacta
    50221 ccaacatata agtcttctag agtgattgtg ttgccactat aatctttaat tttttgttga
    50281 ggtccatcca aatcaaattt tactggcttt tgtgtactac tttgttcatc ctccgctctg
    50341 acgctactag ttaccccgat ggcaaagagt gccagtagca aagttaatgt ctttttcatt
    50401 tcgttctctc cttttgctca ttttttaaga caaggcttat tataccaatt cttgcgctaa
    50461 aaagataggg attgattggc tgaggcgatc ggagaagtcc tagatttctc tgagtggctg
    50521 ccactcactt aatgtttcac tattttattg ggatatgcta atacttcaag atatctttat
    50581 atcgtctata gtcaagagcc tatttgacac tttatctcta tgtaaataat ttgcacactc
    50641 tgttaagtgc tctttttggt cgcttatcct cttttaaagt tgttttatgt cagttgaaaa
    50701 cgatgtttct tgagtaacct aacttacctg atatctcgta tcgtgatacg ttatttatca
    50761 atattatgaa atagaacaac gatattaggc attcttttcg attaacttcg aatagcttaa
    50821 taaatgttta tcatctgcaa tttttagcat aatttaaaga aatacgactg tatcttgata
    50881 ggtactgttt tttgatgtct ttaacaatat attctcaaat tttcaag
//
LOCUS       DAUGJR010000010        46495 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUGJR010000010 DAUGJR010000000
VERSION     DAUGJR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46495
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.010"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            143..685
                     /locus_tag="VH800_000560"
     CDS             143..685
                     /locus_tag="VH800_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361649.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            809..1588
                     /locus_tag="VH800_000561"
     CDS             809..1588
                     /locus_tag="VH800_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEQ8361650.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFVTNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            2387..2983
                     /gene="recR"
                     /locus_tag="VH800_000562"
     CDS             2387..2983
                     /gene="recR"
                     /locus_tag="VH800_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEQ8361651.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            3084..4130
                     /locus_tag="VH800_000563"
     CDS             3084..4130
                     /locus_tag="VH800_000563"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEQ8361652.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            4321..5712
                     /locus_tag="VH800_000564"
     CDS             4321..5712
                     /locus_tag="VH800_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEQ8361653.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            5792..6487
                     /locus_tag="VH800_000565"
     CDS             5792..6487
                     /locus_tag="VH800_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEQ8361654.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLFVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYFGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLALAFSKEK"
     gene            6735..8279
                     /locus_tag="VH800_000566"
     CDS             6735..8279
                     /locus_tag="VH800_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEQ8361655.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            8586..10205
                     /locus_tag="VH800_000567"
     CDS             8586..10205
                     /locus_tag="VH800_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8361656.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            10333..12333
                     /locus_tag="VH800_000568"
     CDS             10333..12333
                     /locus_tag="VH800_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEQ8361657.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTIQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(12357..12635)
                     /locus_tag="VH800_000569"
     CDS             complement(12357..12635)
                     /locus_tag="VH800_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEQ8361658.1"
                     /translation="MTTKKAYMYVLECVDKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(12625..13401)
                     /locus_tag="VH800_000570"
     CDS             complement(12625..13401)
                     /locus_tag="VH800_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEQ8361659.1"
                     /translation="MIKAILKEGERIDQLFSSDVGIIQNKDVFSYSIDSVLLSRFPKM
                     PSKGLIVDLCSGNGAVGLFASTRTKAAIVEVELQERLADMGQRSIQLNQLEDQVTMIC
                     DDLKNLLNHVPRSGVDLMLCNPPYFKSHESSKKNVSEHYLLARHEVTTNLEEICQVAR
                     HALKSNGRLAMVHRPDRFLEIIDSLRANGLAPKRVQFVYPKLGKSANMLLIEAIKDGS
                     IEGMTILPPLVVHKENGEYTDHIFEIYFGAASKGKPNHDH"
     gene            13519..14259
                     /locus_tag="VH800_000571"
     CDS             13519..14259
                     /locus_tag="VH800_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEQ8361660.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKLAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRIDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            14459..15121
                     /locus_tag="VH800_000572"
     CDS             14459..15121
                     /locus_tag="VH800_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEQ8361661.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            15102..17345
                     /locus_tag="VH800_000573"
     CDS             15102..17345
                     /locus_tag="VH800_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEQ8361662.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVFFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
                     FLTYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGRTS
                     WHLETVR"
     gene            17416..18456
                     /locus_tag="VH800_000574"
     CDS             17416..18456
                     /locus_tag="VH800_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEQ8361663.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFDQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKIDAARDLIHDLRLSGEDDIKLIAIMLGQFRLFLQLTILARDVKNEQQL
                     VISLSDILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            18553..19158
                     /locus_tag="VH800_000575"
     CDS             18553..19158
                     /locus_tag="VH800_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEQ8361664.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQTLINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIVNWKKVSELYQAAK"
     gene            19325..19552
                     /locus_tag="VH800_000576"
     CDS             19325..19552
                     /locus_tag="VH800_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361665.1"
                     /translation="MLRKKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGERQQTA
                     DLKMRKRLEKLFKNRYLKNLKRLSKLLWMQI"
     gene            19537..19785
                     /locus_tag="VH800_000577"
     CDS             19537..19785
                     /locus_tag="VH800_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361666.1"
                     /translation="MDADLAQMDVLGLYYDDNHLSLVNTVKAYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            19782..20372
                     /locus_tag="VH800_000578"
     CDS             19782..20372
                     /locus_tag="VH800_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEQ8361667.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSIPDMQEYSLVYSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTAYYLQVLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLIALYSSGL
                     GGATQASEEVNGLGYVQLVQLPYVINEWYRGNLNMI"
     gene            complement(20486..21706)
                     /locus_tag="VH800_000579"
     CDS             complement(20486..21706)
                     /locus_tag="VH800_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8361668.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(21713..22741)
                     /gene="queA"
                     /locus_tag="VH800_000580"
     CDS             complement(21713..22741)
                     /gene="queA"
                     /locus_tag="VH800_000580"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEQ8361669.1"
                     /translation="MNTNNFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            22943..23647
                     /gene="nagB"
                     /locus_tag="VH800_000581"
     CDS             22943..23647
                     /gene="nagB"
                     /locus_tag="VH800_000581"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEQ8361670.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDV
                     EAEAKRYNQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIEDVPKQAISMGIASIMKSEMIVLLAFGQEKADAIKGMVFGPITEHLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            23766..24482
                     /locus_tag="VH800_000582"
     CDS             23766..24482
                     /locus_tag="VH800_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8361671.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            24777..25739
                     /locus_tag="VH800_000583"
     CDS             24777..25739
                     /locus_tag="VH800_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor"
                     /protein_id="HEQ8361672.1"
                     /translation="MTKILTALDDKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            25752..27557
                     /gene="pepF"
                     /locus_tag="VH800_000584"
     CDS             25752..27557
                     /gene="pepF"
                     /locus_tag="VH800_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8361673.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFA
                     GHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFILLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMEKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            27933..29129
                     /locus_tag="VH800_000585"
     CDS             27933..29129
                     /locus_tag="VH800_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEQ8361674.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            29195..29902
                     /locus_tag="VH800_000586"
     CDS             29195..29902
                     /locus_tag="VH800_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEQ8361675.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            29965..31020
                     /gene="prsA"
                     /locus_tag="VH800_000587"
     CDS             29965..31020
                     /gene="prsA"
                     /locus_tag="VH800_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8361676.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            31407..34025
                     /gene="alaS"
                     /locus_tag="VH800_000588"
     CDS             31407..34025
                     /gene="alaS"
                     /locus_tag="VH800_000588"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEQ8361677.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYDPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAEIV"
     gene            34386..34601
                     /locus_tag="VH800_000589"
     CDS             34386..34601
                     /locus_tag="VH800_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361678.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            34598..35359
                     /locus_tag="VH800_000590"
     CDS             34598..35359
                     /locus_tag="VH800_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEQ8361679.1"
                     /translation="MKKKKNSFLRLLKMSLLSSLAGGIIGGMVGAFLGYHGGRLDHLT
                     FLKDDVINLIILLNRLVVVTDLTLSFVFLTQLKKETAVYNTIEEDDISENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            35378..36073
                     /locus_tag="VH800_000591"
     CDS             35378..36073
                     /locus_tag="VH800_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8361680.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTSIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(36165..37321)
                     /locus_tag="VH800_000592"
                     /pseudo
     CDS             complement(36165..37321)
                     /locus_tag="VH800_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(37459..38772)
                     /locus_tag="VH800_000593"
     CDS             complement(37459..38772)
                     /locus_tag="VH800_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEQ8361681.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(38747..39706)
                     /gene="nrdF"
                     /locus_tag="VH800_000594"
     CDS             complement(38747..39706)
                     /gene="nrdF"
                     /locus_tag="VH800_000594"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8361682.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(40039..42198)
                     /gene="nrdE"
                     /locus_tag="VH800_000595"
     CDS             complement(40039..42198)
                     /gene="nrdE"
                     /locus_tag="VH800_000595"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8361683.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFSAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKDLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(42218..42436)
                     /locus_tag="VH800_000596"
     CDS             complement(42218..42436)
                     /locus_tag="VH800_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEQ8361684.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            42829..43092
                     /locus_tag="VH800_000597"
     CDS             42829..43092
                     /locus_tag="VH800_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEQ8361685.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            43097..44830
                     /gene="ptsP"
                     /locus_tag="VH800_000598"
     CDS             43097..44830
                     /gene="ptsP"
                     /locus_tag="VH800_000598"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEQ8361686.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            45015..46442
                     /locus_tag="VH800_000599"
     CDS             45015..46442
                     /locus_tag="VH800_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8361687.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVSFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
BASE COUNT        14266 a         8180 c         9646 g        14403 t
ORIGIN      
        1 ttgatggttg ttatgaatac catgctaaaa tattctattg attatttatc agcaacaagg
       61 tatcgtttaa aaataccaaa agatacaggt gtcttgatag ttattggttt ttaaggtata
      121 ctatttttga aaaggagata aaatgactaa aaaaccaaca caactaatag cttatacctc
      181 tattttggtc gcatttgcga ttttgattcc gataatcatg cctcttaagc ttattattgg
      241 accagcttcc tttactctgg cgagccatgt tcctttgttt ttggctattt ttatgtcgat
      301 tccagtagca attttggtcg ctcttggtac cacattaggt tttttattag ctggactacc
      361 tttaattatt gttttaagag cactctctca tttattgttt gctattttgg cagcgtggtg
      421 gttaagtaga aaaccacaac tgatgacatc ggcagtaaaa tgttttagtt ttgcgttttt
      481 cattaatgtc attcatggct tggctgaatt tttagttgtc tatattttaa cagcaaccac
      541 agcaacttct atgtcttatt tttggtctat gctaggcttg attggcttag gttcgcttat
      601 tcatggcata ttggatttct atcttgcttt agttctatgg cgttttttag caaaaaactt
      661 aaaacttccc accataaatg cctaagacta aaatagagat agttatatga taatgacgag
      721 ccctttcttg ttgaaagggc ttgcattttt taggaaaatt gatatactaa agtgtgtgtt
      781 tgtgaataca gtaacaaaag gagatatcat gaaaacacca gaacagattt tagaagcaac
      841 tattcatatt ggggaacata aggttaccaa aacttttttg gctaaatcta tcttaggctt
      901 tattggtgga gcgatgatta gccttggtta tttactatac gtgagaattg ccgccagtgg
      961 tttagaaact tttggtgctt tttccagtat cgtaggagct tgtgcttttc cgattggtct
     1021 aattattatt ttaatggcgg gtggagaatt aattacaggg aacatgatgg ctgtttctgc
     1081 agctttgttg gccaaaaaaa ttaagtttag cgagcttgcc aagaattggc ttatcattac
     1141 cttgtttaat gtgattggag ctgtttttgt agcttttgtg tttggtcatt ttctaggctt
     1201 aacatcagct ggtattttta aagaagaagt gattgaggtg gcccatgcta aaatagcagc
     1261 gagccctttg caggcactag tatcaggaat tggttgtaac tggtttgttg gtttggcctt
     1321 gtggctatgc tatggggcaa atgatgctgc tggtaaattc cttggtactt ggtttcctgt
     1381 catgaccttt gtagcccttg gttttcagca tagtgtagca aatgcttttg tcattcctgc
     1441 tgctattttt gaaggaggag caacatggtt ggattttgtc actaatttta tttttgtcta
     1501 tagtggtaat attatcggtg gagccatttt tgttagtttt ttatatttta aagtttacta
     1561 tcatccgcaa aagagtaaaa ctcaatgaga aaatattttt ttagactgag ggcgtcctat
     1621 tctcagtctt ctttttataa tttatggtaa aataagaagc gaagtttaaa aaatttagct
     1681 aaataatggt tagtttattc cctaaaaaag gagtattccc aaaaaatccg taaaaagaat
     1741 ttgccatggg agtagttccc aaaataatgc agatcattta gttgtctttc aaaaatagcc
     1801 ttgatagggt aaaaagtgga cagtgatgca gcaacagatt catcaggcgt acaaactgtc
     1861 ttatggtttg tgcttagaga tttcttaata atgcttttgg taatacactt ttagtgaaga
     1921 aagtgtagca tgaaagctta aagataacca tgagttcgct ttatgcacta ttgttgagaa
     1981 aaatagcata gtcaattgag taaacatcat ttctgcatgg aatgaaacaa ttcctataaa
     2041 cttatatcat aaggatggtt tgcggtttct aaaaaagtaa catgaatcaa aaaacaaaag
     2101 ccaaatatcc caaggccaag gtaacaagtc gagtaaaaaa gtttttactt ggctaatcca
     2161 aacggttctg tcacgattca cgctaaaatt ggaactgttg agacttgtat cacagacaat
     2221 tcagatcaga ccttagtaac ttacaactta aatgtagtag cttataatac aaataacgaa
     2281 gataatattg cggttgctgt tatgtatcca catattacga atatatcggc aaagatgtga
     2341 gagcgcttta tgtggcgata tatggaaaac aataaaggag aacttagtgc tttatccaac
     2401 acccattgca aagttaattg acagttactc taaacttcca ggaattggta tcaagacggc
     2461 gacgagatta gccttttata ctattggaat gtcaaatgaa gatgtcaatg attttgctaa
     2521 aaacttatta gcagctaaaa gagaactgac ctattgttcg atttgtggaa accttaccga
     2581 tgacgatcct tgtcacattt gcacagacac gagtcgtgat cagacgacca ttctggtagt
     2641 agaagatgct aaagatgttt ctgccatgga aaaaatccaa gagtatcatg gctattatca
     2701 tgtgcttcac ggcttgattt cgcctatgaa tggtgtgggg ccagatgaca tcaaccttaa
     2761 aagtttaatt acccgtctaa tggatggtaa ggtgagcgaa gttatcgtag ctaccaatgc
     2821 cacagcagat ggggaagcaa cgtccatgta tatttcacgt gtcttgaaac cagccgggat
     2881 taaggtaact cgtttggcaa gaggtctcgc agtaggttca gatattgagt atgctgatga
     2941 agtaacatta ttgagagcta ttgagaatcg tactgaactt taatgatcat gttggtgcct
     3001 ttactcgcaa agagaggttt tgaaaaggct acatcttttt gttataataa aaaaacattc
     3061 aattcagata agaaaggtta gctatgtcca aacaaacgtt agttctatta tacggaggcc
     3121 gctcagcaga acgtgaagtc tcagtgcttt cagcagagag tgtgatgcga gcagtcaact
     3181 atgataagtt cttagtaaaa acttatttta ttactcagat gggccaattt atcaaaactc
     3241 agcaattttc agaaaagcca tcggaatcag aacgcttgat gacaaatgag acgatagagc
     3301 taactcaaaa aataaaacca agtgatatct atgaagaagg tgcagttgta tttcctgtat
     3361 tacatggacc tatgggagaa gatggctcta tccaaggttt cttagaagtg cttagaatgc
     3421 catatatagg gactaatgtc atgtcttcta gcatagctat ggataaaatt actactaaac
     3481 gtgtcttaga atcaattgga attccacaag ttgcctatac tgtttatatt gacggacaag
     3541 atttggaggc ttgtttagtt gaaactttag caagacttac ttttcctatc ttcgtaaaac
     3601 cagctaatat gggttcttct gtggggattt ccaaagccca aacaaaagta gaattaagaa
     3661 aagcgattca gttagccctg acctatgaca gtcgtgtctt gattgaacaa ggcgtggttg
     3721 caagagaaat tgaagttggt ctccttggaa atgataaggt taaatcaact ctaccaggag
     3781 aagtaatcaa ggacgttgat ttttacgact accaggcaaa atatgttgac aataagatta
     3841 cgatggccat tccagcagat gtagaccaga gtattgtgac agaaatgcgt tcttatgctg
     3901 aagtagcctt taaagcctta ggtggttgtg ggttgtcccg ttgtgacttt ttcttgaccc
     3961 aagatggaca ggtttacctt aatgaattaa acaccatgcc aggctttacc caatggtcta
     4021 tgtatccact cttatgggaa aatatgggat tggcttatcc agatttgatt gaagagctgg
     4081 tgacactggc acaagaaatg tttgaccagc gtgagagcca cctgatttaa acctatgaga
     4141 tgaataaaca ttgacttgga tggaacggca aacatcgtca agatgtgacg ttcgtccttt
     4201 ttttgttgct ctttatagta gagtcattaa gggagtttga cattttagaa atttttctaa
     4261 tgttttgtgc tataatagat aggacatcgt aaatactagt gttcttagaa agaaaacaaa
     4321 atgaaattaa ccttacacga agtggctaaa atagttgacg cccaaaataa tgtgtctgac
     4381 ttagacgacg ttcctctgca tcacattgaa tttgatagcc gaaagattac aaaaggagac
     4441 ctctttttac ccttaaaagg tcaaagggat ggtcatgagt ttattgattt agcctttcaa
     4501 aatggagctg tcgctacttt ttcagaaaaa gaattgccgg ggaaacctca ccttcttgtt
     4561 gaagactgcc taaaagcttt tcaaaagcta gcccattatt atattgataa gatgcgcgtg
     4621 gatgttattg ctgtgacagg ctcaaatggt aaaacttcca ccaaagatat gataggagct
     4681 gtcctatcaa ccacttacaa aacttacaaa acgcaaggaa attacaataa tgagattggt
     4741 ttgccttaca ccgttctcca catgcctgac gatacggaaa aaattgttct tgaaatggga
     4801 caagatcaca tgggagatat tcgtcttctg tctgaaattg caaggcctcg tattgcagtt
     4861 ttaaccttag tcggcgaagc tcatttagaa tattttggaa gccgagacaa aatagcccaa
     4921 ggcaaaatgc agattgttga cggcatgaat tcagatggga ttttaattgc tccgggagat
     4981 ccgattattg acccatatct tccagaaaat cagatggtta tccgttttgg aaatcagcag
     5041 gaaattgacg ttactggtat tcaagaagac aaagatagct taacgtttac aacaaatgtg
     5101 ttagcaacac ctgtgtccct acctctacca ggaaaataca acgcgaccaa tgctatggta
     5161 gcagcctatg taggaaaact attggcagta acagacgagg atattatagc tgctttacag
     5221 actgtgacgt tgacaggtaa tcgtacggag tggaaaaaag cagccaatgg tgctgatatt
     5281 ttgtcagatg tctacaatgc caacccaaca gccatgcgtc tgattttaga aacatttgct
     5341 aacatagcaa agaaccccgg aggaaaaaag attgcagtgc tagcagatat gaaagaactt
     5401 ggaaaggatt cagtgatact tcattctcag ttaattgaca gcttaacatc aggtaatatt
     5461 gatcagcttg ttttttatgg ggatcatatt aaagaattag cacggttggc aagtcaggtt
     5521 tatcctgctg agcaagtaca ttatttttta aaaactgaac aagaagacca gtttgaagcc
     5581 atggcacaat atgttcaaaa cattcttaat ccctttgatc aaattctttt aaaaggcagc
     5641 cactcgatgt cgctagaaaa gttagtagat cgattagtga ctgacaagaa ttgtgacagc
     5701 tatcagcctt gatttttata aaactttcag agaaaggctt gttctctcat gaagattaag
     5761 gtataatgaa aaaatataga aagggacgat tatggatttt tttgcaattg accccatcgg
     5821 actgcctcat acctcactta tcttttactt gtcgtcactc ttgatagcgc ttttgtttgt
     5881 ttttttgact tttcaagcat ataggttaaa atcttatcgt tattttttct tgtttttaca
     5941 gttatctcag gtgattggct tatacacatg gtacgtgtta agggggtttc ctttagatga
     6001 agctttgccg ttgtatcatt gtcgcatcgc tatgttagct atcttttttc tacctgatcg
     6061 taacaagttt aagcaattat ttatggtttt ggggataggt ggaacattcc ttgcactttt
     6121 atcgccagat ctttatccgt ttagattatg gcatgtagca aatgtctcgt tttattttgg
     6181 tcattatgct ttgttagtga atggtttgat ttacctcttg cgtttttacg atgccagtca
     6241 gttaagactg ctatcagtag tacgctattt agcaactgtt aactttcttc ttctgttggt
     6301 cagtttagcc acgaaaggaa attatggttt tgtgatggat attccagtga ttcatacgcg
     6361 tcatttgcta cttaattttg tgatcgttac aagtggcttg acttttatgg ttaaaataac
     6421 cgaatatttt taccttaaat ttggtgaagc tcaacagctg gcacttgctt tctctaaaga
     6481 aaagtaggtc gttgaaaaag cacttaaaat cagctataat aagaagagtc tgggatgatt
     6541 tccaggctcg atttttaaaa aaaagacact cattgatagc ccaagataag ttataatacc
     6601 agttttgaag aactttagag gctaatcgta tatggagaaa cccaatgtag cccaactctt
     6661 ttgataaaca agtaatacct aacgaaaata actcagagaa aagctctgcc attttactat
     6721 acaaggaaaa aagaatgtca cttacagaag aaattaaaaa acgccgtact tttgccatca
     6781 tttctcaccc ggatgctggt aagacgacta ttactgagca actattatat tttggtggtg
     6841 aaattagaga agcagggaca gtaaaaggca aaaaatcagg tacgtttgca aagtccgact
     6901 ggatggatat tgaaaagcaa cgtggtatct ctgttacttc atctgttatg caatttgatt
     6961 acgcgggtaa acgtgttaat attttggata cacctggaca tgaggatttc tcggaagata
     7021 cataccgtac cttaatggct gtggatgcgg ctgtcatggt tgtagattcg gctaaaggta
     7081 ttgaggcgca aacgaaaaaa ctttttgaag ttgtcaaaca tcgtaatatt cctgtcttca
     7141 cctttattaa caagttagac cgtgatgggc gtgagccttt agaactcttg gaagaattag
     7201 aagaagtttt agggattgct tcttatccga tgaactggcc gattggtatg ggacgcgcct
     7261 ttgagggctt atatgattta cataataaac gtttagaact ctataaggga gacgagcgtt
     7321 ttgcaagtat tgaagacggt gatcagctgt ttgccaataa tcccttttat gaacaagtca
     7381 aagaagatat tgaacttctt caagaagcag gtaatgactt ttcagaacaa gctattcttg
     7441 atggtgacct aactccagtc ttttttggct ctgcccttac gaactttgga gttcagactt
     7501 ttcttgatac tttcttggag tttgccccag aacctcatgg tcacaagact acagaaggta
     7561 atgttgttga ccccttagct aaagattttt caggttttgt ctttaaaatt caagctaaca
     7621 tggaccctaa acaccgtgac cgtattgctt ttgtgcgtat tgtttctggt gaatttgagc
     7681 gcggtatggg agttaatttg acacgcactg gcaaaggcgc taagctctcc aatgttactc
     7741 aatttatggc agaatcacgg gaaaatgtga cgaatgctgt tgctggggat attatcgggg
     7801 tttatgatac aggaacttat caagttgggg ataccttaac agttgggaaa aataaatttg
     7861 aatttgaacc cttaccaact tttaccccag aaatcttcat gaaggtttct ccgaaaaatg
     7921 ttatgaagca gaaatccttc cacaaaggta ttgaacaatt agtacaagaa ggagcaattc
     7981 agctttataa gaattatcag acaggcgaat acatgctggg tgctgtgggt caactgcagt
     8041 ttgaagtctt taaacatcgt atggaaggtg aatacaacgc tgaagttgtg atgacaccaa
     8101 tgggtaaaaa gactgttcgc tggatttcag aagatgattt ggatcaacgc atgtcttcaa
     8161 gccgaaacat tttagctaag gatcgttttg accaaccagt tttcctattt gaaaatgatt
     8221 ttgcccttcg ctggtttgca gacaaatacc cagatgtcac tttagaagag aaaatgtaat
     8281 tgaaacatga ttttcaacag tctaacgttt tggagatcaa tttactgagc aactttttaa
     8341 aagaaatgag tggctagtta tctcttttgc agatttaaga ttctatcaaa aaacgatatc
     8401 ttcacaactg taagcatatt tatgatttag cggataatcg tgaaagcgtg ttattgctta
     8461 tattagcctt atttcctatc tttttgattc taattgtgtt acactagtta ggttgttaat
     8521 caaacgacga aaattaaaag gtttataagg cagcttcgca ctgccttttt agaaaagaga
     8581 aacaattgaa atttacagaa tttaacttat cacaagacat ccaatcagct gttgttaccg
     8641 ctggttttga gaaagcatct cctatccagg aaatgacgat tcctctcgca ctagaaggga
     8701 aggatgttat tggtcaagca caaacaggaa ctggtaaaac agcagcgttt ggtctaccaa
     8761 ccttgaataa gattcgtact aacgaaaata tcatccaagc attggtcatt gcaccaacgc
     8821 gtgaattggc tgtacaaagt caggaagaat tgttccgttt tggacgtgaa aaaggggtta
     8881 aggttcgctc tgtttacggt ggatcaagta ttgaaaaaca aatcaaagcc cttaaatcag
     8941 gtgcccacat tgtcgtggga acaccgggtc gcttgttaga tttgattaag cgcaaggctc
     9001 ttattttaga tcatgtggaa accttaatcc ttgatgaagc agatgaaatg cttaacatgg
     9061 gattcttgga agacattgaa gctattatta gtcgtgtccc agcagaccgt caaaccttgc
     9121 tcttctccgc aacgatgccg gcacctatta aacaaatcgg ggttaaattc atgaaagacc
     9181 ctgaacatgt tcaaattaag aacaaagaat taacaaacgt caatgttgat caatactatg
     9241 ttcgtgtgaa agaacaagaa aaatttgata ctatgacccg tctgatggat gttaaccagc
     9301 cagaattatc catcgttttt gggcggacta agcgccgagt tgatgaaatt acacgtggct
     9361 tgaaacttcg tggtttccgt gccgaaggaa tccatggtga tcttgaccaa aataaacgct
     9421 tacgtgttat ccgtgatttc aaaaacgacc aaattgatat tcttgttgcc actgatgtag
     9481 cagcgcgtgg ccttgatatt tcaggagtta cccacgttta taactacgat attacccaag
     9541 atccagaaag ttatgttcac cgtattggtc gtacaggtcg tgccggtaaa tctggtgagt
     9601 ctatcacttt tgtctcacca aatgagatgg gctacctctc aatgattgag aacttaacga
     9661 aaaaacagat gaaacctctt cgtccagcaa ctgctgaaga ggcctttcaa gccaagaaaa
     9721 aagtagccct caagaaaatt gaacgcgact ttgcggatga gactattcgt tcaaactttg
     9781 ataaattcaa aggcgatgct gtccaattgg ctgccgaatt cactcctgaa gaattagctt
     9841 tatatatttt gagcttaacg gttcaagatc cagatagctt accggaagtt gaaattgcac
     9901 gtgaaaaacc attaccattc aaatatgtgg gtggtggtca cggcaataaa aatggcaaag
     9961 gtggtcgtgg acgtgacaac cgtaaccgtg gtgatcgccg tggcggctat cgtggtgacc
    10021 gtaacagaga tgagcgtgat ggtgaccgtc gtcgtcaaaa acgtgataag cgtgatggtc
    10081 acgatggcag tggcaaccgc gatttcaaac gtaaatcaaa acgtaatagt aaagactttt
    10141 tcaataaaga gaaaaaatca agtgctaaaa atactggttt tgtgattcgt cacaaaggtg
    10201 aataagctta aagagagttg atgagagtca gctcttttta attttctgaa aaagttgctt
    10261 ttataatgga atctgttata atggtttcag ttatttttgt gataattttt aaaaaattag
    10321 gaggagtata agatgtctga tagccatctt actgcctttg acaaagcttc aaaagcaggt
    10381 tttattattg ctttaggtat tgtttatgga gatattggaa caagccccct ttatacgata
    10441 cagtctctag ttgaaaatca aggaggggtt aatcaggttt ctgaatcctt tattttagga
    10501 tcaatctctt taattatttg gacactgacc ttaatcacaa caatcaagta cgttttgatt
    10561 gctctaaaag cggataacca ccatgaaggt gggatttttt ctttattcac cttggtacgt
    10621 aaaatgtcac cgtggctcat tattccggcg atgattggag gtgcaacact tttgtctgat
    10681 ggggctctta cacctgcggt aacagttact tcagctattg agggcttgaa agccgttcct
    10741 ggtctgagtc acatctacca aaatcaaacc aatgtcatta tcacaactct agtgatttta
    10801 atagtcttgt ttggtattca gcggtttgga acaggtttta ttggtaaaat ttttggacca
    10861 gttatgttta tctggtttag ttttctaggt gttagtggtt tttttaatac gttggggcat
    10921 ctggaaattt tcaaggctat caatccttac tatgctctgc atttgctgtt tagtcctgaa
    10981 aaccatcgtg ggatttttat cttggggtcc atttttcttg cgacaacagg agctgaagct
    11041 ctttattcgg atttaggaca tgttggtcga ggaaatattt acgtgagctg gccctttgtt
    11101 aagatgtgta ttgtgttgtc ttactgtggc caggctgcgt ggattttagc gaataaacac
    11161 tcaggtattg aactaaaccc tttctttgct agtgtgccat cacaattaag agtttacctt
    11221 gttagtttgg caaccttggc agctattatt gcctcacagg ctcttatttc aggctccttt
    11281 accttggttt cagaggccat gcgtttgaaa attttccctt tgtttcgtgt gacttaccca
    11341 ggggcaaatt tggggcaatt gtatattcct gtcattaact ggattttatt tgcagtgacc
    11401 tcttgtactg ttttggcttt tagaacatca gcccacatgg aggcagctta tggtcttgct
    11461 attaccatca ccatgttgat gacaacaatc ctcttaaagt attacttaat caagaaagga
    11521 acgagaccca tcttggctca tttagtgatg gctttctttg cccttgtaga attcattttc
    11581 ttcttggctt cagctatcaa atttatgcac ggtggctatg cggttgttat cttggcactt
    11641 gcaattgtct ttgtcatgtt tatctggcat gcgggcacac ggattgtttt caagtatgtg
    11701 aaatctctta atttgaatga ttacaaggag cagattaaac aacttcgtga cgacgtttgt
    11761 tttgacctct accaaacaaa tgttgtctac ctatccaatc gtatgcagga tcatatgatt
    11821 gaccggtcta ttttatactc cattttagac aagcggccaa aacgcgctca agtttattgg
    11881 tttgtaaatg tccaggtaac tgatgaacct tatacagcta agtacaaggt agatatgatg
    11941 ggaacggatt atatggttcg agtcaacctt tatcttggtt ttagaatgcc acagactgtg
    12001 ccacgctatt tgcgcacgat tgttcaggat ttgatggaaa gtggccgttt acccaaacaa
    12061 gaacaggaat ataccatcac acctggtcgt gatgttggtg attttcgctt tgttttaata
    12121 gaagaacggg tctccaatgc acgtcaattg agtaactttg aacgctttat tatgcagact
    12181 aaggcaagca ttaaacatgt taccgctagt ccaatgcgtt ggtttgggct tcaatattca
    12241 gaagtaaccc ttgaagtggt tcccttgatt ctatcagatg tcttgaagtt accaatcaaa
    12301 gaattggtgc ctgtggaaga cagtgaagca taaaaaaatc attgagatga taagtctcaa
    12361 tgatttttct tttctttttg atgagtagca atataggcca atttctggct tcttgttttt
    12421 cgttttttaa agagtgcttc agcgctcatc gcagcctctt tgctatcaaa cacttcgtaa
    12481 taaagtaaag aaacaggtaa ccggtagcga gtatatttag ccccctttcc tgcgttatgt
    12541 gtagctaagc gttttttcaa atcagttgta taaccagtgt agagggtttt atcaacacat
    12601 tctaacacat acatataagc ttttttagtg gtcatgatta ggttttcctt tggaagcagc
    12661 accaaaataa atctcaaaaa tatgatcagt gtattctccg ttttccttgt ggacaactaa
    12721 aggaggtaaa atagtcatcc cttcaataga accgtctttg attgcttcaa taagtaacat
    12781 attagctgat ttacctaatt taggatagac aaattgtacc cttttagggg caagaccatt
    12841 agctctaagg ctatctataa tttccaagaa tcgatctggt cgatgaacca ttgccagacg
    12901 accatttgat ttaagggcat gacgggctac ctgacaaatc tcttctaaat tagtggtcac
    12961 ttcatgacga gccagtaaat aatgttcaga gacgttcttc ttagaacttt cgtgactttt
    13021 aaagtaaggg ggattgcaga gcatcaaatc aactcctgaa cgtggcacat ggtttaggag
    13081 gttttttaaa tcatcacaaa tcatggttac ttggtcttcc agttgattga gctggataga
    13141 gcgttgtccc atatcagcaa gccgttcttg taattctact tcaacgatgg ctgccttggt
    13201 tctagtgcta gcaaataagc caaccgcccc atttcctgag cacaaatcca caattaaccc
    13261 tttggaaggc atcttgggga agcgggataa gaggacgcta tcaatagagt aactaaagac
    13321 atccttgttt tgaataatgc caacatcact tgaaaagagt tgatcaatac gttcgccttc
    13381 ttttaagatt gcttttatca tacctgttat tttaacataa aataggcttg aggtgaatgt
    13441 ttgaagagtg attttgactt tcgaaaagtc agctttcgtg atacaataag taagattatt
    13501 ctattaaagg agaagcctgt gttttacgct tacttacgcg gtttagtagt ctttttatta
    13561 tgggttgtca atggcaatgc ccactaccat catgaagaaa agatgttaga tgcttctgag
    13621 aattatattc tggtagcacc ccatcgaacc ttttgggatc cagtttacat ggcatttgca
    13681 gcacgtccta agcagtttat ttttatggct aaaaaagagt tgtttgcaaa tcgtctcttt
    13741 gcttggtgga ttaaaatgtg tggtgctttt cctattgatc gtgacaaacc gagtccagat
    13801 gctattcgtt accctgttaa tatgctcaaa aagagcaatc gttctcttct tatgtttcca
    13861 agtggaagta ggcattcgca agaggtcaaa ggaggggtcg ctgtgattgc taaattggct
    13921 aaggtcaaga ttatgccagc agcctatcag gggcctatgt cggtcaaggg attactagcg
    13981 ggagaacggg ttgacatgac ttttgggaat cccattgacg tctcagatat taaacgcatg
    14041 aatgatgaag ggattgctga ggtggcaaac cgtattcagg cagagtttga tcggattgat
    14101 gacgagttgg cacctttcca accaggcaaa gcaaggaacc ctttaactta tctctaccgt
    14161 ttaccattag gattggtttt ggtggtggta ttattattaa ccatgttatt ttcctatatt
    14221 gctagttttg tttggaatcc agataaacat cgccattaag aacatgaggg ctaacatgtg
    14281 cctgaaataa gaagtgattg agattagtct tctattgaaa gaagccgcta atgcttaatc
    14341 acttttttca tttctaaaaa agatattcga tgataccctt aactctttta agcacaaaaa
    14401 atgacaatac tactatactt ttggatatca tttacgaata aaaagatgag gtaaaaaaat
    14461 gttagacgaa ttattaatta aaggaaaatc gtttttgaga gagcggtatt ttctgccata
    14521 cctaattagt cttttattag gactttttct aatactaagc ttcagttttt tgttctgggg
    14581 aaataggcag agcaaggcag ccgttcctgc tttgagagaa atatcgcctg tgaaacagca
    14641 ggttagtgaa gaaaaaaagg aaattcaaga agatagcagt attttagtgg atttaaaagg
    14701 cgccgtacaa aaagagggag tttataagct aactgctagc agtcgtgtgc gagatgtcat
    14761 tgaactagct ggaggcctaa cttcagaagc tgataaacat gctattaatt ttgcagaaaa
    14821 actaactgat gagcaagttg tttatgtacc taaacaagga gaagagattt ctgtgctacc
    14881 aagatcatta gtttctggta aaaaagaaac tgccagcaag gatcagtcaa aggttcatat
    14941 taataaggcc agcttagaag aactacaaca tatcccaggt attggtgcta aaagagctca
    15001 ggatattatt gatatgagag ataagttagg tggttttaaa gcgttagaag atctccgtca
    15061 ggtttcgggg attggcgaaa aaacgctcga gaaattaaaa gatgacattt tcttggacta
    15121 agctagtgcc cctgtcaaag attcaatttg cttttttaat cttggttttc ttttatcaaa
    15181 tccatagccc tagctggtta acgtttctcc ttagccttag tttgatttgc ttacttgtca
    15241 agcgtttgtc taaaaaagaa tttctcggtg tctttgccat ccttagtttc tgtgctttgt
    15301 ttttgctgta tcagaaacag cagttggttc aaaaactgga aattcagcca gtacaaataa
    15361 cctctgtagc attagttcct gatagtattc ggattaatgg tgatcaatta gctgttcttg
    15421 gacgtcacgg gaaacattct tatcagttat tttaccgttt gaaaagccaa gcagaagccc
    15481 aattgttcaa gaaagagcac cgttggttag tgatgcacgc aaaagtgaca ttggaaaaag
    15541 ctgaggaagt tcgaaatttt aaaggcttta attatcagac ttttttgact tatcaaggaa
    15601 tttacaggat agggaaggta gagcaaatag aacagcttga agtgatttca cccgagtcaa
    15661 tatgtgacta tttgtcctct ttaagacgac gagccattgt tcattgccag cagcattttc
    15721 caagacctat gtctcactac ctgacgggcc tcctttttgg ttatttagat aagtcgtttg
    15781 gtgagatgac agattattat agtcagttgg gtatcattca tctctttgct ttatcaggga
    15841 tgcaggttgg cttctttctc acttgtttta gaagggtgtt gctattactc gcagttcctt
    15901 tggaatggat aaaatggata gagcttcctt ttgcttgctt ttatgccgcg ttgacaggtt
    15961 atagtatttc tgttattcga agcctcgtgc agtcgcagtt gcgtcattta ggaataaaag
    16021 gattagacaa tctggcttgt acttttttac ttgtcttttt atgggatgct catttcttaa
    16081 tgactgttgg tggcgtatta acgtttagct atgctttttt gttaacagtg gttactgttg
    16141 aagaattatc aggagctaaa agacagttgg tacaagtctt gaccatttcc ctaggaatat
    16201 taccattttt gctcttttat ttttccagtt ttaacccaat gtcaatggtc ttaacagggc
    16261 tcttgtctta tctctttgac ctttttattt tgccccttct ttgtctggtt ttttgtctat
    16321 cccctttggt gactgtctca atatgtaacc atctttttat tttattagaa aaagtcattc
    16381 aatttctcgg aaatactttc aatagttccc ttgtttttgg aagcccgacc agttggcact
    16441 tgcttatctt ggtgattagc ttcgctattt tttatgatta tcggcaggtg cgacaacgag
    16501 ttatcacttg cggtttggtt atagcgttga cacttttgtc tgtcaaatat cctttgacca
    16561 atgaagtgac ctttatcgac attggccagg gagatagtat tttggtgagg gagtggacag
    16621 ggaaaaatct cttaatagat gtaggtgggc gccctttctt ttcttcaaaa gagcactggc
    16681 gacgaggaca tcacgtagct aatgctcaga aaaccttaat tccttactta aaaagtagag
    16741 gtattcacac aattgaccaa ctattagtaa ctcacgcaga tactgatcat atgggggata
    16801 tcgaagtggt tgccaaagct attcggataa aggagatttt gactagtcaa ggcagtttaa
    16861 gccatccaag ctttgttagg cggctaaggc gtttaaaatg tcacgttagg gttttagcag
    16921 ctggagacca gttgcctatt atgggaagtg tcttacaggt actctaccct tggcagttag
    16981 gggacgggaa aaataacgat tctttggtac tttatggcag gctcttaaat cgaacttttc
    17041 ttttcacagg tgacttggaa aaagaggggg aaaacgagat cataaaacgt tatcctcaac
    17101 taagagtaga ttatttaaaa gcaggtcacc atggatcaaa tacctcttct agtgcagctt
    17161 ttttagacca tattcagcct aaagtggcct ttatttctgc tggaaaaaat aaccgttatc
    17221 agcatcctca cagagaaacc ttagcccgtt tggaagacag acaaatcact tattaccgaa
    17281 cggatacgca aggagctatt cgtttgactg gtcggacaag ctggcatctt gaaacggttc
    17341 gttagttaaa attccagcct gacgaagaaa caagcagtcg ctttcctttt aggagaaaga
    17401 tgatataata aaagcatgat tgcgatagaa aagattgaaa aactgagtaa agaaaatttg
    17461 ggtcttataa cccttgtcac aggagatgac attggtcagt atagccagtt gaaatcccgc
    17521 ttaatggagc agattgcttt tgataaggat gatttggcct attcttactt tgatatgtct
    17581 gaggccgctt atcaggatgc agaaatggat ctagtgagcc tacccttctt tgctgagcag
    17641 aaggtggtta tttttgacca tttgttagat atcacgacca ataaaaaaag tttcttaaaa
    17701 gaaaaagacc taaaggcctt tgaagcctat ttagaaaatc ccttagagac tactcgacta
    17761 attatctttg ctccaggtaa attggatagt aagagacggc ttgttaagct tttgaaacgt
    17821 gatgcccttg ttttagaagc caaccctctg aaagaagcag agctaagaac ttattttcaa
    17881 aaatacagtc atcaactggg tttaggtttc gagagtggtg cctttgacca attacttttg
    17941 aaatcaaacg atgattttag tcaaatcatg aaaaacatgg cctttttaaa agcctataaa
    18001 aaaacgggaa atattagcct aactgatatt gagcaagcca ttcctaaaag tttacaagat
    18061 aatattttcg atctgactag acttgtccta ggaggtaaaa ttgatgcggc tagagatttg
    18121 attcatgatt tacggttatc tggagaagat gacattaaat taatcgctat catgctaggc
    18181 caatttcgct tatttttgca gctgactatt cttgctagag atgtaaaaaa cgagcaacaa
    18241 ctagtgatta gtttatcaga tattcttggg cggcgggtta atccttacca ggtcaagtat
    18301 gcgttaaagg attctaggac cttatctctt gcctttctaa caggagcggt gaaaaccttg
    18361 attgagacag attaccagat aaaaacagga ctttatgaga agagttatct agttgatatt
    18421 gctctcttaa aaatcatgac tcactctcaa aaataggcgt tggaccgctt tccaagagat
    18481 aatcaaatta gttgaaagct cttatttttt gcgataagat agacgtatca taaaggaaaa
    18541 gaggacagga aaatggctat tattttacca gaacttccat acgcgtatga tgctcttgaa
    18601 ccacagtttg atgcggagac aatgactctt catcatgata aacaccatgc cacttatgtc
    18661 gctaatacca atgcggcttt agaaaaacac ccagagatcg gagaaaatct ggaggaacta
    18721 ttggcagatg tcactaagat tccagaagat attcgtcaaa ccttaattaa taatggtggc
    18781 ggacacctaa accatgcgct tttctgggaa ctattatcac ctgaaaaaca agacgtcact
    18841 cctgatgttg cacaagccat tgatgatgct tttgggtcat ttgacgcctt taaagaacaa
    18901 tttacagcag ctgctactgg acgttttggt tcaggttggg catggttagt tgttaataaa
    18961 gaaggacaac tcgaaatcac atcaaccgct aaccaagata ctccaatttc agaaggcaaa
    19021 aaaccaattc tagcgcttga tgtgtgggag catgcttact acttgaatta tcgtaatgta
    19081 cgtccaaatt atatcaaagc tttctttgaa atcgttaatt ggaaaaaagt atcagaactt
    19141 taccaagccg ctaaataaga aaagggtttc caatctcaaa aagagattgg ttttttaagt
    19201 gcttttgtga ataacagtgt ggggacatca ttttttagaa aagataaaaa tagtttgtct
    19261 ttttaatgta attccttgat ttttagctaa atttagctag aatagaatgg ataggagatt
    19321 ttaggtgtta agaaagaaga aaactaccat tgtagggatt attttaggaa tgatgatagt
    19381 gaccttactt gtcggctgtt tgactggtaa aaagaaaggc tttcctccta aagcaggtga
    19441 gcggcagcaa acggctgact taaaaatgag aaaaagatta gaaaaactgt tcaaaaaccg
    19501 ttacctgaaa aatctaaaga ggctaagcaa gctgttatgg atgcagattt agcgcaaatg
    19561 gatgtcttag ggctctatta cgatgacaac catttgagtt tggtcaatac ggtcaaggcg
    19621 tatttaaagg aatttggcat tggtgaatcc caaattgcct tttcctacaa agacctcaat
    19681 tcaggcagga ctgctgccat gaatgaccat cagccaatga ttgcaggaag cacctataag
    19741 ctgccattaa acatgctggt ggtagataag gcaaattatc catgacagag cgttttgaca
    19801 ttacagaaac tgattatgaa tatgatcagg aacatcatgc ctatgttgct cagttcaatg
    19861 gtgccatgtc tattccggat atgcaagaat attccttggt gtactcagaa aacacgccag
    19921 cttatgctct agcagaacga ttgggtggca tgaataaggc ttaccaatta tttgaccgct
    19981 acgggaaggt atccggggct attacgacca ttgatcgtaa tggcaataaa atcaccaccg
    20041 cttactattt gcaagttttg gattacttgt ggcagcatca ggataaatat aaggatatct
    20101 tgtactacat tggtgaatct ttccctgatt tgtattacaa gacttatttg cctcatgtaa
    20161 aggtttatca aaaaccgggt tatgtcagag aagccttaaa tgtaggtgcc attgtttgcg
    20221 aagagtctcc ttatttgatt gctctttatt catctggttt gggtggagca acacaagcat
    20281 cagaggaagt caatggcctt ggttatgtgc agcttgttca gctaccatat gtaattaatg
    20341 agtggtatag aggcaatctc aacatgatct aatactcagt tgacattagt ctgatagtag
    20401 acatacttac tgatgacagt cactaaaata agttgttgct cattaaaaaa gcttggcctg
    20461 tttcttcagg tcaagctttt tgagattaat gctgtgtttt tgaggtctta ttgtcacctc
    20521 ttgtttcttg ataatggtga agcaattttt tgaatttttt aacggcagcg cgtgttagct
    20581 gcttagatga tttgccattt ctgctgtaaa tgggattgtg cttatccctt tgctgttcta
    20641 aatcgggaac tagaaaagtt gcatcaggac tattaattgc tttttcaata aaagccggat
    20701 caaaaagcag aatagggtca atatcaagca gacggtgcaa gtcatcgttt tggttgccat
    20761 aattgaaaga agaaccattg acaatactat ttcgcgttag gttatcagga tctagtgcta
    20821 ctaaaaattg tccagattct gacaaaataa actctgagtg aaaatgaatt aaaatcttat
    20881 agttggcttg aggaatattg tctgtataga ctgcctgatg attgccatta gcatctaaaa
    20941 tactagcaac cttattatgg tatctagaag attcataaag agcataatcg tcatcttcta
    21001 gagtagccaa atatttggct aaggcatccg catcggtttt ccctttattc ccataatgtg
    21061 agcgaaccca ctccgtttgc tgggttgata tgaggtaacg gagttgatga attttccgat
    21121 taaaacggct ataaggaatg tgttcgagat taacataata agcctgaatc agggtagata
    21181 attggtccca aaaaggatct gttggcgata gctttggact taattgtgcc aatacttgct
    21241 gtgtttgttt tgattgtcct gtcaactcgt ctggcatctt taaatacgtc aagagcagtt
    21301 gtaaccgttt ttgagcttct tgaggcgtct gtgccatctc ctcttgttgc cagagctttt
    21361 gaaagtcagg tgatcctatc aggcgaatgc gactataaag ttgttcgaaa tgataagagt
    21421 ttcctctaac agcgagttgt tcaaggtatc ctttttggat ggctttatag gaccatccgt
    21481 ccttatcgag ctttcgaaca taatcaagca agtcgtggcg taatttaata gcttctgaaa
    21541 gctggagttc tcgtaattta ggatagtttt ggtaaaaagg tgccactaaa tcttgataaa
    21601 gtttgtgttc tttttcaaag gcaatccgct gatagtcttt ctgccaaaaa ctgacgcaaa
    21661 aagtcagaaa catcaagaag aatagccatt ttccaagtaa tttcataggt ttttagttga
    21721 caaacatggc atcgccaaag ctaaagaaac gatacttttc gtcaaccgcg tgtctgtaag
    21781 cttcaaggac aaagtcacgc cctgcaaagg ctgatactag catcacaagg gttgattttg
    21841 gaagatggaa attagttgaa aaagcatcaa ctaccttgaa ttggtagcct ggtttaataa
    21901 aaatattggt ccaacctgaa tcagcttgaa tgtccccttg gaacttacct ccgatggttt
    21961 ccaacgtacg aatagaggtg gttcctacag cgacaacacg accgccagct tgtttgacgt
    22021 ctcttagggt ttgcgctgct tcttctgaga gggaataaaa ttccgaatgc atatcatgct
    22081 catcgaggtt atccacggaa acaggtctaa aagtcccaag ccctacatgt agggtcaaat
    22141 aaaccaaatg tacccctttg gcttcgattt ttttgagcaa gtctgttgtg aagtggagac
    22201 cagcagttgg ggcggccgca gagccatttt ctttagcata aacggtttgg tatcgctcag
    22261 catcctctaa tttttcgtga atataaggag gcaatggcat ttcgccgagg ctctctaaaa
    22321 cttctaagaa aatcccatca tagctgaatt caacaattcg tccaccatgt tctaattcgt
    22381 cgataatggt ggctttgaga cgcccatctc caaaattgac ttggctacca accttgagcc
    22441 gtttggctgg cttggctaaa acttcccatt gatctccttg tgtattttta agcaaaagca
    22501 attccacatg accatgagta tcgggttttt ctccataaag tctggcaggc aagacacggg
    22561 tgttattcat gacgagggca tcccctggat ttaattgatc aatgatatgg tcaaaatggc
    22621 tatcaaccat agttttttga cggtgatcaa taatcaatag ttttgaactg tctctttttt
    22681 cgagtggggt ttgggcaatc aattcttctg gtaactcaaa atcaaaattg ttagtattca
    22741 ttgggactcc tttaaagcca ctagtaaatc tcttcctagt aactctttca tgtaagataa
    22801 atcttttcta ttatatcact tgtcgtctaa cccgtcatct ttaatctttc atcagaaagt
    22861 aaaggatagg cttgacaaaa attggtatat accatataat aaaaacacga aaggtctata
    22921 ccaattagaa aaggagaatg acatgaaaat tattcgggtc caagatcaga ttgaaggtgg
    22981 gaaaatcgct tttaccttat tgaaagatag cttagctaag ggagctaaga cgttaggatt
    23041 agcaacagga agttcaccaa ttagttttta ccaagaaatg gtcaaaagtc ctttggattt
    23101 ttcggactta acaagtatta acttggatga atatgtcggt ctttcagtag agagcgatca
    23161 gagttatgat tattttatgc gtcaaaacct ttttaatgcg aagcctttta aaaagaatta
    23221 cttgcccaat ggtttagcaa ccgatgtcga agcagaagct aaacgatata accaaatcat
    23281 tgcagagcat ccgattgatt ttcaagtgct tgggattggg cgtaatgggc acattggttt
    23341 taacgaacct gggacctctt ttgaagaaga aacgcatgtg gtggatcttc aagaatcaac
    23401 cattgaagcc aatagtcgtt tctttacaag tattgaggat gtgccaaaac aagctatctc
    23461 tatgggaatt gcctccatca tgaagtccga aatgattgtt cttcttgcct ttggacaaga
    23521 aaaagctgat gcgatcaagg gaatggtttt tggaccaatc acagaacacc tcccagcaag
    23581 tattctccaa aaacatgatc atgttatcgt cattgtggat gaagctgctg cgtcacaatt
    23641 agactaacct aaccagtcgt taaaccttgt aagaacaaaa atgaggagat agtcaacttc
    23701 atttaagaag aagtcttgta acttctattt cttttgcaag ggtaaattta tgttacacta
    23761 ctaatatgcg tttagataaa ttattagaag gtacaaaagt tggctctaga agtcaagtga
    23821 agaaactgat taaggctcaa ggggtttggg ttgatcacat gcctgccaga aatggtcgac
    23881 aaaatgttga tcctggcttg caactgattg aggtgactgg acagcgagtg acgcatccta
    23941 aacattctta cattatcctc aacaagccat caggggtggt ctcagctaag aaagatacta
    24001 actatttaac cgttattgat cagcttgctg aagaagataa aagtccagac ttgtatcctg
    24061 ttggcagatt ggatagagat accgaagggt tggttttact cactgataat ggtcccctag
    24121 ggtttcggat gttgcaccct agtcatcatg tttctaaaac gtatcttgta accgttaatg
    24181 gcttgttagc agaagatgcc tcagattttt ttgcagctgg tatttgtttc ccaacaggtg
    24241 aacaatgcca accagctcaa ttgactattc ttaaagccga tacagaccag tcacaggcta
    24301 gtttgaccat ttcagaagga aaatttcacc aagtgaaaaa aatgtttttg acctatggtt
    24361 tgaaagtgac ctctctgaaa cggacgcact ttgcaggact ggaactcggt catttagcca
    24421 gcggagaata tcgttatcta acagcgtcag aaaggcaact cattaaaacg tatctggact
    24481 gagcaaaaca tgctttcaaa aagaagctat tcttgcttaa tcaataaagt gtccattgac
    24541 tattatagtc atgatgagtc cgacttttgc tatgtttagt catcttgttg ttacaaaatc
    24601 aggtaagcaa aaagattcaa ttcccactgt ctccttaacc tgaagcgtta taaaaaccct
    24661 tgtgttaaac tctcataaat tggaaatggg agtgtttttt gatggctaaa aaaactaaag
    24721 ctacttaaag tttggtactt agttttcgaa taataaggtg gaagatctaa taggaggtga
    24781 caaaaatatt aaccgcttta gatgataaga atcagctcat ttcgctagta actcagccta
    24841 tttcaacgaa accgcctttt cgttgcccag cttgcaaatc tcctgttcgc ttgcgtcagg
    24901 ggacaattag acgacctcat tttgcccatg tacaactagc tcattgtcaa ttccaagcag
    24961 aaaatgaatc tgaggaacat ttgacgttga aggcaaaact ttacaccagt ttagtccgaa
    25021 cagaagctgt ctgtattgaa aaatatcttc ctgagctgca acagatagca gacctttggg
    25081 tgaatgataa gttagcctta gaaattcagt gcagtccctt gccagttgag cgtctaaaga
    25141 aacgcaccaa agcctatcaa gaaaaggggt atccggtacg atggttactg ggaagaaaat
    25201 tgtggcttaa cactcactta actgctttgc aaaaacagtt tctttacttt tcatctagtt
    25261 tgggctttca tttgtgggag ctggatgcag ctgcaaatct gctacgtctc aaatatttaa
    25321 tccatgaaga cttatttggt aaggtaagtt acctaaccaa aaccatttct ttagaccaca
    25381 atattatgga aatgtttcgg ttaccctatc agcaagaaat cctttattct tatcagaaaa
    25441 aaatgactgt gaacctatct aaaagaatac aaagagctct tttagctaga cacccgaaat
    25501 ggctacgacg acaagaaaag gcttacttat caggctataa tttacttatg ttaacaactg
    25561 atgcttttta tcctcaatgg agaccagttc aatcttccag cggtttttgt caaattaaag
    25621 gaaatcttcg cccttattat gaaagtttta aagtctatta taaaaaagaa aaggataaga
    25681 aggtgcaaac gcttttttca ccaaaatatt atgttaaaat ggatagtaat agaaaatgag
    25741 aaggagatgt tatgactgat aatcgcagcc atttagaaga aaaatacact tgggatttga
    25801 gcactatttt tgcaacagat aaggattggg aagctgaagt cagtgactta gctactgaag
    25861 ttgaggcatc taaaggtttt gctggtcatt tgctggattc tagtgctaat ttgttaaagg
    25921 ttacaaaaac atatttagaa ttggctcgtc gtgtggagaa agtctatgtt tatgctcaca
    25981 tgaaaaatga ccaagacact actgttgcca agtatcaaga ataccaagct aaggcttcag
    26041 gcttgtatgc aaagtttagc gaagtctttt cattctatga tccagaagtg atgatgcttc
    26101 atcaagaaga ctatcaggct tttcttactg aaacccctga gttgaaagtg tacaaccatt
    26161 tctttgacaa attattccaa gcccgcgaac atgttcttag tcaagcagaa gaggaattat
    26221 tagcaggagc tcaagaaatt ttcaatggtg cggaagaaac ctttagtatt cttgataacg
    26281 ctgacattgt ctttccagta gttaaaaatg ataaggggga agatgttgaa ttaacccatg
    26341 gtaacttcat tagcctaatg gaatctaagg accgtagcgt tcgccaagct gcttatgaag
    26401 ccatgtatag tacttatgaa cagttccaac atacttacgc taaaaccttg caaaccaatg
    26461 tgaaagtgca aaactataag gcgcgtgttc ataaatacga ttcagcacgt caagctgcca
    26521 tggctgctaa ctttattcca gaagctgttt acgacacttt attagaaacg gttaataaac
    26581 atttgccact cttacaccgt tatttgaaat tgcgtcaaga ggttcttggt ttagacgatt
    26641 tgaagatgta tgatgtttac acaccattat ctgaaacaga tctagccatt ggttatgatg
    26701 aggctttgga aaaggctgag aaggttttgg ctgtttttgg taaagattac gcagatcgtg
    26761 tgcatcgtgc ttttaccgaa cgttggattg atgttcatgt caataaaggg aagcgctctg
    26821 gggcttattc aggtggttcc tatgatacca atgcctttat tctgttgaat tggcaagata
    26881 cacttgataa tctttacaca cttgtccacg aaacaggcca cagtttgcat tctactttca
    26941 ctcgtgaaac acagccttat gtgtatgggg attatagtat cttcttggca gaaattgcat
    27001 ccacaacgaa tgaaaatatt atgacagaag ctctcttaaa tgaggttcaa gatgagaaag
    27061 aacgctttgc cattttaaac cattacctcg atggtttccg tggaacagtt ttccgtcaaa
    27121 cccaatttgc tgagtttgaa catgccattc atcaagctga tcaaaaagga gaagtgttaa
    27181 caagtgaata ccttaaccag ctatacgctg atttaaatga aaaatattat ggtttaagta
    27241 aaaaagataa tcattttatt cagtatgaat gggcacgtat tcctcatttc tattacaatt
    27301 attatgttta ccaatatgca acaggttttg cagctgcaag ctatttagca gataagattg
    27361 tgcatggcac acaagatgat atcgatcatt acttggccta cctcaagtca ggaaattctg
    27421 attacccact tgaagtgatt gctaaagcag gcgttgatat ggaaaaaggt gattatttgg
    27481 aagccgcctt taaagtcttt gacgaacgtc taacagaact tgaagtactc gtgtccaaag
    27541 gcatacacaa aagctaaaat cacaaaagtc aaggacaaaa agagtttagg attgatagaa
    27601 atggagattc acagttggtg tgaatctcca tttctatcgg tcattttctt tttatatttt
    27661 agtggattat cagtcctgaa aagcaggctt cattgacctt agtttgacgg tttctttttt
    27721 gtctttttta ttgtgtggtc actcacttaa ataaaaccaa tagttgagta aggcgcttca
    27781 gattaacgct attctattgt tttagagata acgttcgcat aaaacatatt tttattatat
    27841 ttgacatttt ataaaagaga taatagaatt aaaatactaa catttatgtt ttttaaaaaa
    27901 taaacgttcg tataataaaa aaggagtttt tcatggaaaa aacaaaacgt tatatcattg
    27961 caacagcagg gatacttctc cacttaatgt tgggatcgac ctatgcttgg agtgtttatc
    28021 gtaatccaat tttacaagag accggttggg accaagctcc tgtcgctttt gccttttctt
    28081 tagctatttt ttgtttaggt ttatctgctg cttttatggg aaatttagtt gaacaatatg
    28141 gtcctcgtct aaccggaacg gtgtcagcta ttctttatgc ttctggaaat atgctgactg
    28201 gtttagcgat tgatcgtaaa gaaatttggc ttttatatat tggttatggt gttattggtg
    28261 gcttaggact tggagcggga tatatcacac cgatatcaac tattataaaa tggtttccag
    28321 ataaaagagg catggcaaca gggtttgcta ttatggggtt tggttttgcg tctttattaa
    28381 caagtccgat tgcccagtgg ctaattgaaa cagaaggttt ggtagcaaca ttttaccttt
    28441 tagggctgat ttatctaata gttatgcttt ttgcttctca attgataata aaaccaactg
    28501 ctgctgagat agctatacta gataaaaaaa gattacaaaa taacagttat ttaatcgaag
    28561 gaatgaccgc taaagaagca cttaaaacaa aatcatttta ttgtctttgg gtaattttat
    28621 ttatcaatat cacatgtggc ttaggactta tctcagttgt tgcgccaatg gcacaagatc
    28681 taactggtat gagtccagaa atgtcagcaa ttgtggttgg tgctatgggg atttttaacg
    28741 gtttcggtcg tttagtgtgg gctagtttgt cagactatat tggacgccgt gtgacagtaa
    28801 tacttttatt tttagtaagc ataattatga ctattagttt aatatttgca catagttccc
    28861 taattttcat gataagcatt gccaccctta tgacttgtta tggtgcgggt ttttctctca
    28921 ttccgcctta tttaagtgat ctttttgggg caaaggaact ggctacatta catgggtata
    28981 tattgacagc ttgggcaata gctgcattaa ctggacctat gttattatct atcactgttg
    29041 aatggactca taattatctt cttaccttat gtgtttttat tgtcttatac attttaggat
    29101 taatggtagc attaaggtta aagaaatgat gtcctataaa aaatttaaaa gtaaacccta
    29161 gcaaagccta gggttttttt atataattag gtttatggtt aaatcataca gtaaaacagc
    29221 aaatcataat atgcgtcgtc ctgttgtcaa agaagagctt gttcattata tgcgaacacg
    29281 gcagaagcaa accacaggtt ttttagcaga gttagagcaa ttcgcaagac aagaaaacat
    29341 tcctattatt cagcctgagg tcgtggctta tttcaggttt ttattgcaaa gcttacagcc
    29401 aaaacacatt ttggagattg gcacagccat tggtttttct gcgcttttaa tggctgaaaa
    29461 tgcaccagat gcgacgattg tgactattga tcgtaatcga gagatgatcg attttgctaa
    29521 agcaaatttt gctaagtacg acagtcgcca acagatccgc ctgttagaag gagatgcagc
    29581 agatatatta tctacacttg aaggaaattt tgactttgtg tttatggatt ccgccaaatc
    29641 caaatatatt gtctttctac cagagatttt aagactgcta aaagtcggtg gtgtagtcat
    29701 tttggatgat gtctttcaag gaggtgacat tacaaaaccg atcgaagata ttcgacgagg
    29761 tcagcgtact atttatcgtg gcttacagtc tttgtttgat gccaccttaa ctcatccaaa
    29821 cctaacaact agcctggtcc ctcttagtga tggattatta atgattcgta aaaatcaagc
    29881 agatattgta ttaccagatt aagtaacatt gataaattta tgttataata aattagttaa
    29941 agataaaaag gagctcagaa gtaaatgaaa aactcaaata aactcattgc tagtgttgtg
    30001 acattggcct cagtgatggc tttagcagct tgtcaatcaa ctaatgacaa tactaaggtt
    30061 atttcgatga aaggtgatac aattagcgtt agtgattttt acaatgaaac aaaaaacaca
    30121 gaagtatcgc aaaaagcgat gctaaatctg gtaattagtc gtgtttttga agctcaatat
    30181 ggtgataagg tttcaaaaaa agaagttgaa aaggcgtatc ataaaacagc tgaacagtat
    30241 ggcgcttcat tctctgctgc tttggcacaa tcaagcttga cacctgagac ttttaagcgt
    30301 cagatccgct cttcaaaatt agtagaatat gcggttaaag aagcagctaa aaaagaattg
    30361 acaacacaag aatataagaa agcatatgaa tcttatactc caacaatggc agtcgaaatg
    30421 attactttag ataatgaaga gacagctaaa tcagtcttag aggaactaaa agccgaaggc
    30481 gcagacttta cagctattgc taaagaaaaa acaacaacac ctgagaaaaa agtgacctat
    30541 aaatttgatt caggtgcgac aaatgtaccg actgatgtcg taaaagcggc ttcaagtttg
    30601 aatgagggtg gcatatcaga cgttatctcg gttttagatc caacttctta tcaaaagaag
    30661 ttttacattg ttaaggtgac taaaaaagca gaaaaaaaat cagattggca agaatataag
    30721 aaacgtttga aagctatcat tatagctgaa aaatcaaaag atatgaattt ccaaaacaag
    30781 gttattgcaa atgcattgga taaagctaat gtaaaaatta aagacaaagc ttttgctaat
    30841 attttggcgc aatatgcaaa tcttggtcaa aaaactaaag ctgcaagtga aagttcaaca
    30901 accagcgaat catcaaaagc tgcagaagag aacccatcag aatcagagca aacacagaca
    30961 tcatcagctg aagaaccaac tgagactgag gctcagacgc aagagccagc tgcacaataa
    31021 gtaggatttt attgactaat cagttaaaaa aacttataat aatttagtta agaattgttt
    31081 atcaaggatt agatacagaa aagtgacggt tgctgcgagt cattgataat tagataaaca
    31141 tgctacttaa ctttacaaca attgatatcg taaattaaga atgacaagtt cattgaatag
    31201 aggtggtacc gcggttttcg ccctctgtga gatggacttg ttttgtattg aggactattt
    31261 gaaatcaacg aaaggaatag agtagactag gctgccaggc ttatagctga tctcctagca
    31321 agaaagaaga gctgtgtcaa ctggtgtgat tacattacta gcttcagcat aacactgttt
    31381 ttcttactct ttgtatctaa atttttatga aagaattatc gtctgcacaa atccgccaaa
    31441 tgtggttgga tttctggaaa tctaaaggac attgcgttga gccttcagct aacttggttc
    31501 ctgtgaacga cccaacgctt ctttggatca actcaggtgt tgcaaccttg aaaaaatatt
    31561 ttgatggttc agtgattcca gaaaatccac gtattaccaa tgcacaaaaa tcaattcgta
    31621 ctaatgatat tgaaaatgtt ggtaaaacag cacgtcacca tactatgttt gaaatgcttg
    31681 gtaacttctc aattggagac tatttccgtg atgaagctat tgagtgggga tttgaactct
    31741 tgacaagtcc agactggttt gatttcccta aagacaagct ctacatgact tattacccag
    31801 atgacaagga ttcgtataac cgttggattg cttgtggcgt tgaaccaagt cacttggtgc
    31861 cgatcgagga taacttctgg gaaatcggtg ctggtccttc aggtccagat acggagattt
    31921 tcttcgaccg tggtgaagat ttcgatccag aaaatatcgg acttcgcctc ttggctgaag
    31981 atatcgaaaa cgatcgttac atcgaaatct ggaacatcgt tctctcacaa ttcaatgctg
    32041 acccagccgt accacgttca gaatacaaag aattaccaaa caaaaacatt gatacaggtg
    32101 ctggtcttga acgtcttgca gctgttatgc aaggggcaaa aacaaacttt gaaactgacc
    32161 tcttcatgcc aatcatccgt gaagtagaga agttgtcagg taaaacttac gatccagatg
    32221 gcgacaacat gagtttcaag gttatcgctg accacatccg tgcgctttca tttgctatcg
    32281 gtgatggtgc gcttcctgga aatgaaggtc gtggttacgt tcttcgtcgt cttctccgtc
    32341 gtgcggttat gcacggtcgc cgtcttggca tcaacgaaac tttcctttac aaattggttc
    32401 cgactgttgg acaaatcatg gaaagctact acccagaagt gcttgaaaaa cgtgatttta
    32461 tcgagaaaat cgttaaacgt gaggaagaaa catttgctcg tactatcgat gcaggtagcg
    32521 gtcacttaga ttcattgctt gcgcagctta aggctgaagg taaggatact cttgaaggta
    32581 aagatatctt caaactttat gatacttatg gattcccggt tgaattgaca gaggaattgg
    32641 cagaagatgc aggctacaag attgaccacg aaggctttaa gtcagccatg aaagaacaac
    32701 aagaccgtgc gcgtgcagct gttgttaagg gtggttcaat ggggatgcaa aatgaaaccc
    32761 tagctggtat tgttgaagaa tcacgattcg aatacgacac atatagtctt gaatcaagtc
    32821 tttcagtcat catcgctgat aatgaacgta ccgaagctgt ttcagaaggt caagcccttc
    32881 ttgtctttgc tcaaacacca ttctatgctg aaatgggtgg acaggttgct gacacaggta
    32941 gaatcaaaaa tgataagggt gacacagttg ctgaggttgt tgatgttcaa aaagcaccaa
    33001 atggtcaacc tctacacact gtaaacgttt tagcatcact ttcagttgga acaaactaca
    33061 cacttgaaat caacaaagag cgtcgtttgg ctgttgagaa aaaccacaca gctactcact
    33121 tgctccatgc agctcttcac aatgttatcg gtgaacacgc aactcaggct ggttcattga
    33181 acgaagaaga attcttgcgc tttgatttta ctcactttga agcagtaagc aatgaggaac
    33241 ttcgtcacat tgaacaagaa gttaatgagc aaatttggaa cgctcttaca atcacaacga
    33301 ctgaaactga cgttgaaacc gcaaaagaga tgggagcaat ggcgcttttt ggtgagaaat
    33361 atggtaaagt ggttcgtgtg gttcaaattg gtaattattc tgttgaactt tgtggtggaa
    33421 ctcacttaaa taattcttca gaaatcggtc tcttcaagat tgtcaaagaa gaaggtattg
    33481 gttcaggcac tcgtcgtatt attgcagtta ctggtagaca agcttttgaa gcttatcgta
    33541 accaagagga tgccctaaaa gagatcgctg ctactgtaaa agctccgcaa ttgaaagatg
    33601 cagcagctaa agtacaagct cttagcgact cgcttcgtga tcttcaaaaa gaaaatgcag
    33661 aacttaaaga aaaagcagca gctgcagcag ctggtgatgt ctttaaagat gttcaagaag
    33721 ctaagggcgt gcgcttcatt gctagtcaag ttgatgttgc agatgcaggg gcacttcgta
    33781 catttgctga taactggaaa caaaaagact actctgatgt gcttgttctc gtagcagcta
    33841 ttggtgagaa ggttaatgtc cttgttgcaa gcaaaaccaa agatgtccac gctggtaaca
    33901 tgatcaaaga attggcacca attgtagcag gtcgtggtgg aggtaaacca gacatggcta
    33961 tggcaggtgg tagcgatgca agtaaaattg cagagctgct agcagcagtt gctgaaatag
    34021 tgtaaatcca taaaaaacca agttatttag aacttggttt tttatatttg aaatgactac
    34081 catcataacc tttttgacta ttatcgttgt caaaaagaaa aagatatgtt acaattatag
    34141 taacaaatag acatgaggag gtgttagaga aaatgacaca tggtatcaaa cttaagaggc
    34201 agatttgctt atgggcaagt atcctgactc ttttcatttt aagttatcat cttatcaggg
    34261 taatctggtt tggagtaccc ttgagttatc tggttttggg ctttacagga ctagccttgc
    34321 tgttgaatac tttttcttat tttagaaagt aagttataag ttaaaggaga atgaaggaga
    34381 tggcaatgga ggttattctt aaaaatcggc tcaaagaatt acgagctaga gatggaatta
    34441 atcaaacgga aatggctaaa ctggcaggag tatcgaggca gaccatcagt ctcattgagc
    34501 gtaacgagta caccccatca gttataattg ccatgaaaat tgcaaaggta tttcaggaac
    34561 cagttgaaga ggtgtttcgt ctagtggagg tcgaggaatg aaaaagaaga agaatagttt
    34621 tttacgcttg ttaaaaatgt cattgctatc aagtttggcg ggagggatta taggtggcat
    34681 ggttggagcc tttttaggtt accatggagg gagattagat catctcacgt tcctaaaaga
    34741 tgatgtgatt aacctgatta tcttattaaa tcgtctagta gttgtcacag acctcacact
    34801 ttcttttgtt tttttaacgc aactgaaaaa agagacagct gtttataaca caattgaaga
    34861 ggatgatatt tctgaaaatg gttaccgtca gctgaataaa aagcatgctt ataccatgtt
    34921 attgattgcc gtagcttcta ttttatccat gtgcaatgtg ctacttggtc tgaccttaac
    34981 taatgattca cagcatgcca tgctggccat tccgcttctg gatatccttt tattattaat
    35041 ggtcattcct tttcaagctt tagccatgaa acgttacaat gccattcggg gaaccgatgt
    35101 tccttatttt ccaaatttga aagaattaaa acataatatc atggctctag atgaggcaga
    35161 gttacaagcc tatcataaga catcgtttga aagtgtgttg tcattaaatg gagtcatcat
    35221 cccttccttg tatgtgattt tattttttgt ctatctattc actggtcaag tggagttaac
    35281 agccatctta gttttggtgt taattcagct ctatttactc gttaagagtg caacaatgac
    35341 cagacaattt taccgttagc ctaaaaggag actgtttatg aaaggattca ttaattattt
    35401 aaaaatagca gtgctcatta ttctggctat ggttttcaat gtccttccga tgattttatt
    35461 gcaaaagcaa cacgatattc ctatggtact taattgggga attggtattt tctacttggt
    35521 tattgttgga agtgtcctta ttgtattatg gcgtctttat caagctaagc aagacacctc
    35581 tattaaacag caaaaaatga gattggttga ctggggttat ttagcattat tttggttaat
    35641 catccgtgtg atagctattg taggtaccct tgttaaccag ctatggtctg gtcaacaagt
    35701 gagtgctaat gatgctgcaa tacatacctt agctagactt atcaaaggtg gtttcccgct
    35761 ttatactgcc ctatttgtac ttgtgatagc ttttatcgct cctattatgg aagaactagt
    35821 ctttagagga tttcctatga ttgatctctt caaaggaaaa tcacttaagg tggcaggttt
    35881 agtgacctct cttgtttttg ctttaccaca tgccaccaat agtgttgaat ttatcatgta
    35941 cagctgtatg ggcatttttc tctttgttgc ctatcaaaga cgaggaaact taaaagatgc
    36001 tatcttgtta catattttta ataacttgat tgaagtcatt ttgttaatgt caataggctt
    36061 aggagtcata taataaaaag cttcggatgg atgaactgca ccccaaaagt tggacaaaaa
    36121 aactaacatt tggttggact tgtcaagaaa aaatagacat aaagttaagc taatgagtaa
    36181 ctattttttt caaattcaac aggtgagaga taccctaaag ctgaatgcag acgtttgggg
    36241 ttatagtaag tctcactata tttaaaaatc tcaagctgag cttgcttaat agttgcgaaa
    36301 tgagcatcat tgacaagctc tctttttaat gttttataaa aggattccat gagtgcatta
    36361 tcgtatggat taccttttcg attcatactg gacttacatt ttttctgtct aagtaggtcc
    36421 tgaaatcatg ctccggtata ttgagaaccc tgatctgtat ggacgattac cccttcttta
    36481 ggcttttctc tattataagc ttgattgaaa gcttctgtta ccaacttgtc ttgcatacgt
    36541 tagcccattg cccaaccaac aacctttcta ctataaacgt ctatcaagac agacacataa
    36601 agtattcctt cttgtgtagg aatgtaggtt aggtctccta gccataattt attcttacca
    36661 gtcgcttgga aacattgatt aacaagattg ggacgagttc atgaagaacg tcgacggtta
    36721 tagtatttat attgatatcg acttccttta gcatagagac ctagctgatg aaggagtcta
    36781 ccaacacgtt tataattgac atggatgcca cgtctacaaa gttcttgggt aattcgtaca
    36841 cttccgtaac gctctttatg ttcatagaaa atggctttaa tcatttcctt taaagcttca
    36901 ttctcaacat gccttgaaga gggacgacgt tttaaataag catagaaacc tgaacgggag
    36961 acttgaagag tttgacaggt gtgatgacta ttcaagctaa cactattttc cttcagaagc
    37021 tgaaatttta tttccggttt ggcttcaaaa agacctggaa cttttttaga agagctaatt
    37081 cctcctgtag cagtttgtgc tctttttcaa gtttttttgt cttaaattga gcatgacgaa
    37141 gtgcgctccc atgtcctggg aacgcacttt ctccatattt ttcatattct tgaatccatt
    37201 gataaagact attgggatga atttctaaag ttgaactaac catttttaca ggctgctctt
    37261 cctcaaggat gagttttaca gcagagagtt tgaaggcttt atcaaaggtt tttcttggca
    37321 taatgacttt tcctcgtttc cacttaattt tgtgtctact ttattatacc aagtccaact
    37381 ttgcttaaaa tataatgtcc aacttttggg gtgcagttca ttcatccgaa gctttttatt
    37441 aaaaaagtaa ttaactaatc atttaaggat gaaacgataa aactgatagc taaaataaaa
    37501 aatgaggtta gctaatgcta aagggataat cattagtaac gattggcctg taatttcaac
    37561 cagaaaaact ggtgccgcca agggtatctt attgatcaca cctaaaaaga ttgttgcacc
    37621 aaccataatg gctaacgtat ttgatagaga caagggaata aggtactgac taaggatagc
    37681 tagtagtaag ccactagcac ctccaagcat catagaagga gcaattttac ccccttttgc
    37741 tccagaagca aaaactaaag agatagcgac agctttggca acaagtagcc agctaatata
    37801 gctcagatgt ggttcttcat ggagaaaaaa gagtaatcca gctttgccat ttcctaaaat
    37861 ctctgggaag aaaatgctga gtcctgcgat aaggctaaaa gcgatgagaa ctttcggaat
    37921 aaaccactga cttttggcat cagccttagg aaggtgtttc aaaagatgtt tgtaagcgtg
    37981 agcaaagagg gaaaggataa gaccagccag gacggaccca ataagggttc ctagcgtcca
    38041 atgttgctga ggcattaggt attgaatctc atgtcggcct tgtaataaag caactgtttc
    38101 cacagccaca tagctcgtta ggcaggcagc gtatatattt ttaagggacc aacggttaag
    38161 aatagcttct aagataaata aaatagtggc taagggagca ttgtagacag caccaagggc
    38221 agcgccagaa gcgcaggcta ataaaagttt ttgatcggct tttgacaagt tgcatctttg
    38281 gctccaaaga gacgtcaagg taacagcgac ttcccgtgaa gctccttctc ggccgacagg
    38341 agctcccata gatacggtcg ttaattggag ccaaccatgc caaaactgtg tccagggact
    38401 aaatgagatg tcatcttgaa tgatttgctg aatagattga atgtcctttc cttttttagc
    38461 caataggtgc cacccaagac ctgcaagaag tccagcaaag aggagtgaaa gagctcgtct
    38521 ttgtggtgga acactagcaa tcatagtgct aaaagaacct tgactgaatc caaaactgag
    38581 ggactgaatc aggtgaatgg cttttgttaa gataaaagca acaaggccag ctgttaaacc
    38641 tgttaaaaag aggtaaaagg tcaagagtaa aaagtgtcgt ttcataagac tattataaca
    38701 aaagttaaga aaagagactg atagattatc agtctcgtga gcactattag agtccataat
    38761 tataatcgtc atcagacata gcttctacag aaccaagaag atagccattc cctacctgtg
    38821 agaaaaagtc atggtttgat gttcctgttg aaataccatt cataacaatt gggttaacat
    38881 cgtttgcagt atctgggaat aaaggatctt gtcctaaatt cataagagct ttgttagcat
    38941 tgtagcgtaa aaaggtcata acttcctcag tccaccctac gccatcataa agcgttttgg
    39001 tgtatttttc ttcattttca tacagctgat aaaggaggtc atacatccaa tcacgaaaat
    39061 tctcttgctc atcttctggt agttcgttaa aaccaagctg gaatttgtaa ccgatataag
    39121 taccatgtac agattcatca cgaataatta gtttaatgat ttcagcaaca tttgctagct
    39181 tattatttcc caaatagtaa agaggggtga aaaagccaga ataaaaaagg aaagtttcga
    39241 gatatgttga ggcaactttc ttttgtaagg catctccatt agcgtaaatg tcattgataa
    39301 tacgtgcttt ttcttgaaga aactcattat tattagtcca ctcaaagatc tcttcaattt
    39361 cttttttggt gtttaaggtt gaaaagatag acgaataaga tttagcgtga acagattcca
    39421 tgaattgaat attgtttaag acagcttctt cgtgaggagt gcgaacatca gcacgaatag
    39481 cttcgacacc agtttctgat tgcatggtat caagtagggt taatcctcca aaaaccttgc
    39541 caacaagatc tttttcttga agagaaagtt tgcgccaatc gtctaagtca tttgataaag
    39601 ggatacgggt atcaagccaa aattgttcgg tcaacttttc ccaagttgac ttgtcaatga
    39661 cgtcttcgat ttcattccag ttaattgctt cataatatgt agtcatagaa aaatgatctc
    39721 ctaaagagta gtaaagtgcg ttaaggatat cgagataaac cagtagaacc gaccaaagtt
    39781 ctaccggtaa taataagttt aaatagattc aaaagggtaa cgaatgagtt agtgagtggt
    39841 ttaggcagat cgcctaaagc gattgcccaa gaagtaatag atgttttagc atcattaggg
    39901 catatcgagg aattacgaca cggagtaagg aaagtcgata atactttcct tacgtagtta
    39961 gtgagtggtt taggcagatc gcctaaagcg actgccgtag aagtaataga tgctttagca
    40021 tcattacttc ttaaccaatt aaatgacaca agattcacat tggtttgcgc ccacttcttc
    40081 cccatcatcc gtaaaggtac ggatatagta gatagattta atgcctttat tgaaagcgta
    40141 gtttcgtaag atggataaat cacgagtggt ttgtttgctt tgtgttttcc actcataaag
    40201 ctccataggc aactcactac gaaggaatag agttaatgac aagccttggt ccacatgttc
    40261 ggtcgcagcg gcatagacat caataacttt gcgcatgtcc atatcgtaag cagatgtata
    40321 gtaaggaatg gtatccgtag acaaaccatt tgcaggatag tagattttac caattttctt
    40381 ttcttgacgc tcttcgatgc gttgtgtgat tgggtgaata gaagcagagc agtcattgat
    40441 ataagaaata gagccatttg gagcaactgc tagtcggttt tgatgataaa gaccatcttt
    40501 ttgaacggcg tcgcgaagag cctcccaatc tgaagcttgc ggaataaaat ggtctttgaa
    40561 cagatctttc accaaatcag attttggaac aaagtgtcct gtaacgtatt tatcaaagta
    40621 actaccatta gcgtacttag agttctcaaa gccaacaaag gtagtttggc gctcacgagc
    40681 gatgttattg gattcgacca aggtccaata attcaggagc ataaagtaaa tatcagtaaa
    40741 ctcgatggat tctggactgc catattcaat atgatgttga gcaaggtaag aatgtagtcc
    40801 catagctcca aggccaaaag tatgagcttg gctattgcca tgtttaatgg ttggaacagc
    40861 ttcaatgctt gatgaatcag taacaaaagt tagggcacgt gtcatggtct taatagaacg
    40921 gccaaagtct ggtgaggtca tcatgttcag gatattagtg gaacctaagt tacatgaaat
    40981 atcagttccc atttctacaa actcttgcgc atcattgata aggctaggtg tttgaacttg
    41041 taaaatttca gaacacaagt tgctcatgat gatttttcca tcgataggat tagctttatt
    41101 agctgtatca atattgatga tataagggta accagattct tgttgtaatt ttgaaatctc
    41161 tgtttcaaga tcacgagctt taattttagt cttagtaatt ttagggttcg ccactaactc
    41221 atcgtacata ttggtaatgt cgagatagtt aaagggaatg ccatattctt tttcaacatt
    41281 gtaaggacta aagagataca tgtcctcgtt tttacgagct aattcgtaga atttatcagg
    41341 aacggtaatc cctagtgaca aggttttaac acgcaccttt tcatcggcat tttctttttt
    41401 agtagataag aaagcaatga tatcaggatg aaaaacattt aggtaaacaa caccagctcc
    41461 ttgacgttgc ccaagttgat ttgaataaga aaaactatct tcaaataatt tcataacagg
    41521 aacaactcct gaggctgcac cagcatagcc tttgattggt gcgccagctt cacggaggtt
    41581 agacaaggta atcccaactc ctccaccaat acgggataat tgcaaagcag agttgataga
    41641 acgtccgata gagttcatgt catcagttac ttgaatcaag aaacaagaga ccaattcacc
    41701 acgacggctt cgaccagcat ttaaaaagga aggagtagcc ggttggtaac gttggttaat
    41761 catttcaacg gctaaatctt ttgctaagtc ttcttgacca tctgcaaaat acaaagcatt
    41821 aaacaagaca cggtcttcaa ggttttctaa ataatgctct ccatcatttg tttttaaggc
    41881 gtattgctgg tagaacttgt aggctgccat aaatgattta aagcgaaaat tttctgattt
    41941 gattatgcta tctaattcag taataaattc agggcggtat ttctgaataa aagctgattc
    42001 aatgtaatca tttgagatta aatactcaat tttttccgta atggaagtaa aagacatggt
    42061 gtttggcagc acattttcag cggaaaaagc ttttaaagct tctttgtctt tatgaagtgg
    42121 aattttacca ttaacaggac ggttaatttc attatttagg cgaaaatatg aaatatcgcc
    42181 aagatctttg agactcatat tatttttcct tgtcttatta aatcaattct tttaactttg
    42241 caggttggaa gccagaaaat acgaggttat ctgcttcgat aacaggagca gatgtgaagc
    42301 caagactttt cacataatcc actttttcag gatgttcatc gatattaatt tcctggaagt
    42361 tggctccgtg ttgttctaaa aatttcttag tcattttgca ctgcatgcaa ttatttttgg
    42421 aatatactgt aatcatgtct tgtccttcta aaattagtaa tggttccatc ttaaatggaa
    42481 ttactataat agcatataaa aaataaagct aaaaagcaag ctataaactt atctgaaaca
    42541 caacatattg tgttgaaata aaaaacagaa acctaaatat tgtgtcaatc tggattctta
    42601 tggttagagc tctagcgttt tggtgataga agttaagcag ttttaataaa gcattaaagt
    42661 ctgaaaaata aattgtgaaa aacgtgaaaa taaaagaaaa taatttcaca ttttttgtcg
    42721 tttaaatatt taatcttgaa aataaaaaag cattgtgcta taatcggttg ttgtaagggt
    42781 tatcatgtga tggctcaaaa atacacaact taaaaggaga accatactat ggcttcaaaa
    42841 gactttcaca ttgttgcaga aacaggtatt catgcgcgtc cagcgacttt gcttgttcaa
    42901 acagctagca aatttgcttc agacatcact cttgactaca aaggtaaagc agtaaatcta
    42961 aaatcaatca tgggtgttat gagtcttggt gttggtcaag gtgcagatgt tactatctca
    43021 gctgaaggtg cagatgctga agatgccatt gcagcaattg aagaaacaat gactaaagag
    43081 ggattggcat aagactatga cagaaatgct taaaggaatt gcagcctcag acggcgttgc
    43141 tgttgctaaa gcatatctac tagttcagcc ggatttgtca tttgagactg ttacagtcgc
    43201 agatacaaat gcagaagaag ctcgccttga tgttgcactc caagctgcac aagacgagct
    43261 ttctgttatc cgtgaaaatg cagtagaaag cttaggtgaa gaagcagcag ccgtttttga
    43321 tgcccatttg atggttcttg ctgatccaga aatgatcagc caggttaaag aaacgattcg
    43381 cgcaaaacaa acgaatgcag aaacaggtct taaagaagtg actgacatgt tcatcaccat
    43441 ctttgaaggc atggaagata acccatacat gcaagaacgt gcagcggaca tccgcgacgt
    43501 tgcaaaacgt gtgttggctc accttttagg tgtaaaactt ccaaatccag ctacaatcaa
    43561 tgaagaatca atcgttatcg cacacgattt gacaccttca gatactgctc aacttaacaa
    43621 acaatttgta aaagcatttg ttacaaatat cggtggtcgt acaagtcact cagctatcat
    43681 ggcacgtaca cttgagatcg ctgcggtact tggaacaaat gatattacaa aacgtgttaa
    43741 agatggtgat gtgattgccg ttaatggtat cactggtgaa gtgattatcg atccaagcga
    43801 agatcaagta cttgctttta aagaagctgg tgcggcttat gccaaacaaa aagcagagtg
    43861 gtctctcctt aaagatgcgc acactgaaac agctgatggc aaacactttg aattggctgc
    43921 taatatcggt acgcctaaag acgttgaagg tgttaatgac aatggtgctg aagctgttgg
    43981 cctttaccgt actgagttct tgtacatgga ttctcaagac ttcccaactg aagacgaaca
    44041 atacgaagct tacaaggcag tgcttgaagg catgaatggc aaacctgttg tggttcgtac
    44101 gatggatatt ggtggcgaca aggaacttcc ttactttgac cttccaaaag aaatgaatcc
    44161 attccttggt ttccgtgctc ttcgtatttc catctctgaa actggggatg ccatgttccg
    44221 cacacaaatg cgtgcgcttc ttcgtgcctc tgttcacgga caacttcgta ttatgttccc
    44281 aatggttgcg cttcttaaag aattccgtgc tgcaaaagca gtctttgacg aagaaaaagc
    44341 aaacttgctt gcagaaggcg ttgcggttgc tgatgacatc caagttggta tcatgattga
    44401 gattcctgca gctgctatgc ttgcagacca atttgctaag gaagttgatt tcttctcaat
    44461 tggaacaaac gaccttatcc aatacactat ggcagcagac cgtatgaacg aacaagtatc
    44521 atacctttac caaccataca acccatcaat attacgtttg atcaacaatg tgatcaaagc
    44581 agcgcacgct gaaggtaaat gggcaggtat gtgtggtgag atggcaggtg accaacaagc
    44641 tgttccactt cttgtcggaa tgggcttgga tgagttttct atgtcagcaa cttcagtact
    44701 tcgtacgcgt agtttaatga agaaacttga ctctgctaag atggaagaat atgcaaatcg
    44761 tgcgcttaca gaatgttcaa cagcagaaga agttcttgaa ctttctaaag aatacgtttc
    44821 tgaagattaa agggttaaag agttggttta aaccagctct tttttgctag ctaaaaatac
    44881 aattactttt tggtgtgaaa tcatttgagt tatcaaataa ttatcagaat tttcagatat
    44941 ttagtatagc caaatcttga attatatcgg aaaagtgata gaataagatt actatcataa
    45001 aaggagataa aacgttggca aaacaatata aaaatttagt gaacggtgaa tggaaactat
    45061 cagaaaacga gattaccatt tacgcaccag caacaggtga agagttagga tcagttccag
    45121 cgatgacgca ggcagaggta gatgctgttt acgcttcagc taaaaaggct ctatcagatt
    45181 ggcgcgcttt gtcttatgtg gaacgtgcag cttaccttca taaagcggct gatattttag
    45241 tacgtgatgc tgaaaagatc ggcgcgattc tttcaaaaga agtagccaaa ggtcacaagg
    45301 cagctgtcag tgaagttatt cgtaccgctg aaatcattaa ttatgcagca gaagaagggc
    45361 ttcgtatgga aggtgaagtt cttgaaggtg gtagcttcga agctgcaagt aagaagaaga
    45421 ttgctattgt tcgtcgtgaa ccagttggtt tagttcttgc catctcacct tttaattatc
    45481 ccgttaactt ggcaggttct aaaattgctc cagctcttat tgcaggaaat gttgttgctc
    45541 ttaaaccacc aacacaaggc tctatttctg gtttgttact agcagaagct tttgcagaag
    45601 ctggtattcc agcaggtgtc tttaatacca ttacagggcg aggttctgtt atcggtgatt
    45661 atatcgttga gcacgaagcg gttagcttta tcaactttac aggttctact ccaattgggg
    45721 aaggaatcgg taaattagcg ggtatgcgac caattatgct tgagcttggc ggtaaggatt
    45781 ctgctatcgt tttggaagat gcagatcttg ctttagcagc gaaaaatatt gtagccggtg
    45841 cttttggtta ctcaggccaa cgttgtacag cggttaaacg tgttcttgtg atggacaagg
    45901 tggcggatca attggcggct gagattaaaa cacttgttga aaaactaagt gtcggaatgc
    45961 ctgaagacga tgctgatatt acaccattaa ttgatacatc agctgctgat tttgttgaag
    46021 ggttgattaa agatgcaact gataagggag ctactgcttt gacagccttt aatcgtgaag
    46081 gcaatcttat ttcacccgtt ctctttgatc atgtgacaac tgacatgcgt ttggcatggg
    46141 aagagccgtt cggcccagta ttaccaatta ttcgtgtaac cactgtagaa gaagccatca
    46201 agatttctaa tgagtctgaa tatggtttgc aagcttctat ttttacaact aatttcccaa
    46261 aagcttttgg cattgctgag caattagaag ttggaactgt tcaccttaac aataaaacac
    46321 aacgtggaac agataatttc ccattcttag gcgctaaaaa atcaggtgca ggggtacaag
    46381 gagttaaata ttctatcgaa gctatgacaa ctgttaaatc tgttgtattt gatatccagt
    46441 aataaaaaaa ataaacaaaa agttaggtta acttaacttt ttgtttattt tttta
//
LOCUS       DAUGJR010000011        41529 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUGJR010000011 DAUGJR010000000
VERSION     DAUGJR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41529
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.011"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(399..650)
                     /locus_tag="VH800_000600"
     CDS             complement(399..650)
                     /locus_tag="VH800_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361688.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            complement(729..2330)
                     /locus_tag="VH800_000601"
     CDS             complement(729..2330)
                     /locus_tag="VH800_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8361689.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTAD
                     TDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKGPEKA
                     TDKTPEPNRDAPKPIQPPLAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAY
                     THNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAE
                     SSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQD
                     LKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKIT
                     SGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDW
                     QRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGT
                     ISYRTFTAEQASLLTYVVGDKLPRP"
     gene            complement(2432..3820)
                     /locus_tag="VH800_000602"
     CDS             complement(2432..3820)
                     /locus_tag="VH800_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8361690.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKC
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            complement(3817..4470)
                     /locus_tag="VH800_000603"
     CDS             complement(3817..4470)
                     /locus_tag="VH800_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8361691.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            complement(4564..5781)
                     /locus_tag="VH800_000604"
     CDS             complement(4564..5781)
                     /locus_tag="VH800_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361692.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            complement(5794..6468)
                     /locus_tag="VH800_000605"
     CDS             complement(5794..6468)
                     /locus_tag="VH800_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361693.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            complement(6455..7723)
                     /locus_tag="VH800_000606"
     CDS             complement(6455..7723)
                     /locus_tag="VH800_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8361694.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            complement(8146..8430)
                     /locus_tag="VH800_000607"
     CDS             complement(8146..8430)
                     /locus_tag="VH800_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEQ8361695.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            complement(8577..8873)
                     /locus_tag="VH800_000608"
     CDS             complement(8577..8873)
                     /locus_tag="VH800_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEQ8361696.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            9117..9353
                     /locus_tag="VH800_000609"
     CDS             9117..9353
                     /locus_tag="VH800_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361697.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPAAHGPCD
                     DIHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            complement(9629..10558)
                     /gene="prsA"
                     /locus_tag="VH800_000610"
     CDS             complement(9629..10558)
                     /gene="prsA"
                     /locus_tag="VH800_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8361698.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTTAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(11038..11343)
                     /locus_tag="VH800_000611"
     CDS             complement(11038..11343)
                     /locus_tag="VH800_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEQ8361699.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQKQINSLD"
     gene            complement(11345..12541)
                     /gene="speB"
                     /locus_tag="VH800_000612"
     CDS             complement(11345..12541)
                     /gene="speB"
                     /locus_tag="VH800_000612"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEQ8361700.1"
                     /translation="MNKKKLGVRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            13481..14323
                     /locus_tag="VH800_000613"
     CDS             13481..14323
                     /locus_tag="VH800_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8361701.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            complement(14564..15379)
                     /gene="sdaB"
                     /locus_tag="VH800_000614"
     CDS             complement(14564..15379)
                     /gene="sdaB"
                     /locus_tag="VH800_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEQ8361702.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            15743..16252
                     /locus_tag="VH800_000615"
     CDS             15743..16252
                     /locus_tag="VH800_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEQ8361703.1"
                     /translation="MSTDHQLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGYSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            complement(16334..17422)
                     /locus_tag="VH800_000616"
     CDS             complement(16334..17422)
                     /locus_tag="VH800_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEQ8361704.1"
                     /translation="MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(17479..18147)
                     /locus_tag="VH800_000617"
     CDS             complement(17479..18147)
                     /locus_tag="VH800_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8361705.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGEIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIEQLAEAINRENA
                     NSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAVHH
                     RKSI"
     gene            complement(18160..20577)
                     /locus_tag="VH800_000618"
     CDS             complement(18160..20577)
                     /locus_tag="VH800_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEQ8361706.1"
                     /translation="MTETKSPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWKALESDFAGERGEDIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            complement(20787..22091)
                     /locus_tag="VH800_000619"
     CDS             complement(20787..22091)
                     /locus_tag="VH800_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8361707.1"
                     /translation="MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            complement(22101..22409)
                     /locus_tag="VH800_000620"
     CDS             complement(22101..22409)
                     /locus_tag="VH800_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8361708.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            complement(22437..22757)
                     /locus_tag="VH800_000621"
     CDS             complement(22437..22757)
                     /locus_tag="VH800_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8361709.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            complement(23045..24025)
                     /locus_tag="VH800_000622"
     CDS             complement(23045..24025)
                     /locus_tag="VH800_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEQ8361710.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRQQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            complement(24041..24787)
                     /locus_tag="VH800_000623"
     CDS             complement(24041..24787)
                     /locus_tag="VH800_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8361711.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLDVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKVITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            24913..25686
                     /locus_tag="VH800_000624"
     CDS             24913..25686
                     /locus_tag="VH800_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEQ8361712.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLVDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            complement(25923..26099)
                     /gene="secE"
                     /locus_tag="VH800_000625"
     CDS             complement(25923..26099)
                     /gene="secE"
                     /locus_tag="VH800_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEQ8361713.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(26113..26265)
                     /gene="rpmG"
                     /locus_tag="VH800_000626"
     CDS             complement(26113..26265)
                     /gene="rpmG"
                     /locus_tag="VH800_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8361714.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            complement(26314..28650)
                     /locus_tag="VH800_000627"
     CDS             complement(26314..28650)
                     /locus_tag="VH800_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8361715.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPATALQRSRAYEGSPKSRPAWLQKLEAVLPSPQRPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            complement(28689..29069)
                     /locus_tag="VH800_000628"
     CDS             complement(28689..29069)
                     /locus_tag="VH800_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8361716.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            29645..30646
                     /locus_tag="VH800_000629"
     CDS             29645..30646
                     /locus_tag="VH800_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8361717.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHSVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLTCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            complement(30735..32375)
                     /locus_tag="VH800_000630"
     CDS             complement(30735..32375)
                     /locus_tag="VH800_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361718.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDKSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            32622..34118
                     /locus_tag="VH800_000631"
     CDS             32622..34118
                     /locus_tag="VH800_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8361719.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMTSVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGVMWLSIGSPRNAPYLPYLGNISRTYEAYQ
                     EKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISDL
                     VVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVKEKPKNKKGLNRS"
     gene            complement(34746..35060)
                     /locus_tag="VH800_000632"
                     /pseudo
     CDS             complement(34746..35060)
                     /locus_tag="VH800_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535316.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(35321..36952)
                     /gene="groL"
                     /locus_tag="VH800_000633"
     CDS             complement(35321..36952)
                     /gene="groL"
                     /locus_tag="VH800_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEQ8361720.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPATPAPAMPAGMDPGMMGGF"
     gene            complement(36988..37278)
                     /gene="groES"
                     /locus_tag="VH800_000634"
     CDS             complement(36988..37278)
                     /gene="groES"
                     /locus_tag="VH800_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEQ8361721.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            complement(37456..39900)
                     /locus_tag="VH800_000635"
     CDS             complement(37456..39900)
                     /locus_tag="VH800_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8361722.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKDIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            complement(39900..40361)
                     /locus_tag="VH800_000636"
     CDS             complement(39900..40361)
                     /locus_tag="VH800_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEQ8361723.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            complement(40557..40760)
                     /locus_tag="VH800_000637"
     CDS             complement(40557..40760)
                     /locus_tag="VH800_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEQ8361724.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            complement(41280..41350)
                     /locus_tag="VH800_000638"
     tRNA            complement(41280..41350)
                     /locus_tag="VH800_000638"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(41316..41318),aa:Cys,seq:gca)
BASE COUNT        11470 a         8472 c         8015 g        13572 t
ORIGIN      
        1 ttttttatat tttttgaacc taatttatct tttgtcacta acttaattag attttttaca
       61 tgcaattcaa tgtttttgac tgatttcagt ttttaagttt gactgttatg gtacaaccat
      121 taaaaattct atcatacttc agtcaattta caccaacatt agctcttgaa aacgtttcta
      181 cgatgttttt tatgaactgg ttaacttgtc ttttttcgtt ggctattttg agaaaacagg
      241 gctttgggtt ctattttgct tttaatttta gccatgtgac tctcacatca taaggagtgt
      301 ttggcttttt gatgacatca tggctctcaa aagaccaaaa aacttccaat aacttagctc
      361 gtgctctaaa ttattggaag attatttgac ctattactct aatctcgcaa attgtcctct
      421 aatgcgtcaa agatacggtt tagagcaaag ataataaaga aacagacact tcctaacatg
      481 gcaacactcg ctattcccat aaacgtattt tccatgctag gctggcccaa aagaccaatg
      541 ccataactga gtatacttaa gagtaaacag gctgtaccta gttttaggag gtagccatta
      601 cgaacacgtt tttttgtttt ttgactcggg gtggtcactt tctttatcat ctgatgaacc
      661 tcattctaag ttgacgctgt ctctttttga gattggtcaa caggcaggta gcttcttggt
      721 tgtgggggtt atggtcttgg gagtttgtcc cctacgacat aggtcaacaa actagcctgc
      781 tcagctgtga acgtccgata ggaaatggtg cctagtccca taacatttga ctctgaaatt
      841 aagatagaac catcttcttt gatttgctct acaacagcaa cgtgaccata ggttgcatct
      901 gctcctgctt ggcctggtgc aaatgagacg acatagccca ctttaggttt atgggtggtc
      961 acaaaacctg gcttgcgctg ccagtcgcca ccgttaccca tgtacctgtc gacttgataa
     1021 cctagctctt tgacacgatt ataggcgtac caagtgcatt ggccaaagct gtaggtctct
     1081 gacttgtagg tcaaaacgtt ttgtggctga cttcttttat aacctacggg cacttcgcta
     1141 aattgtgtcc cggaagttat cttgagatgt tctggaatct caggtgtgct tccatgatca
     1201 tctatccatt ggtctagttt ggtcatgata tctgctcgtc tttgcccact gccacttgta
     1261 tctgtaaagt aaaccccacc atcaatcaag gtatccaact ggcctagtga ccattttttt
     1321 gctttgaggt cttgtctttc aaaggtttgg tttttgttgg caatgatggt gtcttctacc
     1381 atgtgacgaa tagcaacctc atcgctgtat tttttggcat tgtttgggtt gaagtcaaag
     1441 gcgccataac caaacatatt ggctcctttt tctttagcaa ctccctgagt acctagtgag
     1501 ctttctgcca ttgcaatagc tacgatagct cgaacgtcta gtcctgttag tttttcccat
     1561 tctaataaac gctttccgtt taagcgttct ttatcatagt gaatacctag actgttcaaa
     1621 aaaccatcta gctgttcagc agtaatccca taacggcgtg acaacaggtt gtgagtgtag
     1681 gcagagtcac ctgtccagtg tctcacgtaa gccgctgatg agcgactgct tggttttagc
     1741 ttgctcaggt ctttgtcact ttctctccaa ggtataaaga caggagcagc tgctaaagga
     1801 ggttggatgg gttttggagc gtcacgattt ggctctggtg ttttatcagt tgctttttct
     1861 ggtccttttt caggtgtttt atcaggtgtc tgatcttttt gctgatcagg tgatggggta
     1921 ggtcggccgt ctttgttttg tgactctttt tgagacgact ggtctttggg agatggggtg
     1981 gattgatcac tgctgtctgg ttgcttggtg tcgtttttgt ctttatttgg tttgtcagta
     2041 gcttcagatg atgcctgatc ggtctgctta gtatcatttg aagggggggt tgggtgagtg
     2101 tgtgatggct tatggtcttt ttgggtgtcg tgctgcgacg ctgtttcctt gctttttttg
     2161 tctttttttg gtgtttcact ctcgtcatcc gtatcagtat ctgctgtagt aggctgatca
     2221 gtggatgatg tgctattacg caaggaggta tcagcaacaa ctaatggcac tgcactgttt
     2281 aagagtatgg tacttaatag tgttactgct aacaatttcc ttttcttcat atatgatttc
     2341 tctcctcttt tttatacttg cctaaacaat gatgggtaaa ggtcaaggct tggttaatga
     2401 ttgatgactt ttgtcgtcct actagtatgg atcaatcgtc atgatgggat ggaaaatcaa
     2461 tcgtaaatac catccatctt tgatcaagaa caacaaagcg ataagccaga tgatgctgat
     2521 caagaatctg gtgggtgata aacagcccca atcctgtacc accgtctttc ctgttacgac
     2581 tataatctgg tcgataaaac ggttggaata actgtttcat ctgctgttgt gtcaataatg
     2641 tctctgcttc atttttaatc actagttggt tgtcttttag ttgaatcatc acttggccgc
     2701 ctgatttggt atagtgaaag gcattgtcaa taatattttt aatcgccttt agtagatata
     2761 ctttattggc tttgacgaat tgttcttcaa gattgatagt cactttgagg tgttttagtt
     2821 ctgataagac gagaaagact tccatttctt cttctaggct gctttttagt gaaaacagtt
     2881 cttgattttg agaagctagg gtttcaatct tagataaaga taaaatggat tgaaccagtt
     2941 gggcttgccc ttcaaggacg tctcggcact ttcgcaaata tttgtcacga tctgcaaagt
     3001 caccaacatt atagagcatt ccatcaatca ttccgataac actagtgatt ggtgtcttta
     3061 gctcgtgcga tgtcatgcgt aaaaactcag atttctctct ttctgaatca gaagcttttt
     3121 catactcttt ttgcaaggat ttgatgctcg ttgaaagact cgcatacaaa cggttaatat
     3181 cactagccaa cattgctatt tcatctttgc cgtgaatggt acacgttaag tttggttcta
     3241 ggttgaccat ttttttggcg gtttgtgaca tgctaaggat acgccggcta gaagtcctac
     3301 tatataagta ggcgacaata ctccctacgg tcactgaaaa aatcaatagt gacgggtaga
     3361 ggtcaaggag aactttgcta gcatctgtta cgggttgaag tgaagattgc ccaagcaatg
     3421 tcattttttt tccatcgcgt agggttactt tttgactcat caccttaaca ttagaataag
     3481 agttgtcaaa ggtggtgacg atattaacat tttgactgtc tttgctttca ctgacgccgt
     3541 ctaggagctg caaggaagga tagagcagtt ggttatcact gtctactaag ctgtaccaaa
     3601 tattatcttt gttgattttt tttgttagga tatctctaat ctcggttacc gttttgcctt
     3661 tgatttgctt gcttgtttgg tcaaattcac acttaacttc tttgtctttg actttggtgt
     3721 aataaattgg cattgcaaaa taaagcacta acaaaataga ggtaaccact acaataatta
     3781 agccattgat gaccaaaaag gtttttttga ttagtctcac tcacgctctc ccaataaata
     3841 gcccatgcct gtaattgtct tgaggggaat acccgtcatt tttttacgaa ggttcttgat
     3901 gtggttgtca aggacacgcg tgtccagttc agaatagccc catatgtcat ccatcaattg
     3961 gtctctggtg acaatttttt ggtgacgttt tgctaaataa tcaataatgt catattcttt
     4021 tttggttagt ttgaccaatg ttccttgcca atagacgcta tgttcggtct catcaacaag
     4081 taagtctccg atttggcgct tttcatctgg agtagagacg cgtaatacat tttcgatacg
     4141 tttgattaaa atgagtggtg aaaatggttt ggtcacataa tcactaatca aatggttgaa
     4201 gcttacaagc tgtgtgtact cgtcatctaa tgccgttagc ataataatag ggacatctga
     4261 tgtctttcga attgttttta gcacttctaa gccacttaag gaagggagca tgatgtctaa
     4321 aataatcaga tcataagacg ttgtctgcca cttgtctaag gcagcttggc catcaaatac
     4381 acaatctgga tcatagttat tcgcttttaa aaactcacaa atcacttgac tgatggtatc
     4441 atcatcttca actactaata ttttaaacat aacttccctt tctagattgg cgtttagtgt
     4501 atcaagcagc taaggatgac atcaaagggt catccttttt gacttttatg cttgtttggt
     4561 tgattattca aatcgcaatg cttcaattgg gtctagctta gacgctttaa tggctggtaa
     4621 tagtccaaag acaatcccta taatacaaca aaacgctaaa ctcaagacaa ctgagaacaa
     4681 ggataggata tagggatatt cgagtgatct tgtgatgatc aatcctgata ccatccctga
     4741 aataacccct atcacaccac ctagcaaggt tagaatgacc gcttcaatta aaaattgttt
     4801 taaaataagc ttacgtctag cgccaagcgc ttttttgatc ccaatttctc tcgttctttc
     4861 ggtaactgat actagcataa tgttcatcac accaatacca cctacaataa gagagatact
     4921 agcaatacca gctaataaca caaaattaga tttgtttagg ttgtctagtt ggcgttcaaa
     4981 ttctttaagg ttcatgacac caaacatata atctgattta gggatcgttt gattgagcat
     5041 atcactgaca cgctttgcta caggtttgag gtcatctgcg cgataggtct ggatcgtgat
     5101 ctcaggtgtc gcatccacta caccattaat attataccac tgatgtagcg ggatataagc
     5161 aattttctca gtcccacttg tgaggccact ttgttctttt gattcaaaca ccccaatgac
     5221 cctgaaggga tttcccatca cttcgacaaa ttttccaagg ccatcgtctt ttggaaatag
     5281 tgactcatac aagctttttt caaggtaaat cacctgtttt tggtcaataa agtctttgtc
     5341 tgaaaagtca ctgcctttaa taaatgtcat gcgtctcact tcagctacgt tttttgtgat
     5401 ggcagaaatc tttgcagatg atttttggcc tagatggtag actttgtcat caataccata
     5461 tgagatcagg gcatttttga cgcctttgac ttgctgtatt ttgctaagct cttcttcagc
     5521 cataaaagga agatagtctg gttttttagc atttgacttg tctggaaatt tagggtcaat
     5581 actacttttt ttgttaaaca caatgttaat agtgttattg ctgccaccaa tcaactgtct
     5641 tttggtattt tcggtattac cttcgatgat tgaaaagatt gcgataatgg caccaatacc
     5701 gataataatc cctagcattg tcaaaattga ccgcatcttg tgtgataata tagagcttaa
     5761 agctgcaata atatcttcca ttattttccc cctttactct atatcggaat gttctatatt
     5821 accatctctt aggatcaccg tctttttgca tagggcagct acttcaggct cgtgtgtgat
     5881 gataataatc gttttgccgt tatcattgaa ttgtttaaat aggtccatga tttggacgct
     5941 ggtttttgtg tctagtgcac ctgttggctc atcaccaagg ataaaactcg ggttagtgac
     6001 taaagctctt gcaatcgcta cacgctgttt ttgcccacca gatagctcca tcggtttaaa
     6061 ttcactacgt tcttctagtc ctactagctt taacatctct agggctcgtt tgcgacgctc
     6121 ttttttagga acattcatat aagtcaaggg taattcgaca ttttgacaag ctgttagctt
     6181 gggcatcagg ttaaaatttt gaaaaacaaa gccgattttt tgattacgca aatcagcaag
     6241 ttcattatca gataaggatg acacgtctct gccttcaatg gcatatgagc cagagccagg
     6301 cttatctaaa cacccaatga tattcatcaa tgttgacttt cccgaacctg atggtcccat
     6361 gatggctaaa aagtcaccct cgttaacttc taaatcgatt ccttttaaaa tcgcaaattc
     6421 ttcagttcca agatgatagc tttttcgaat atctttaagg tttaacaata cttcctacct
     6481 ccataccgtc tttcatgcca ggaagcggct gagcaatctt atcttgcata gtcaagccac
     6541 ttgttacctc aacataacct tttgagaagg gcttagtctt gatttcttgt tttttgacct
     6601 tgtttttatc aactttccac acataggttt ttccattttc tgccattgta aaggtttctt
     6661 tcaatacgat cttgccagct tctggaacat tgttgagcac attaacatag gtgtgtgagc
     6721 caatgagtgg ctgcttgtct gattggtcaa gttcaataac ataagggaat tttgcttggt
     6781 ttggattatc ttgttggtca ttgccacctt ggccttgacc ttggcctttt tcctctgctt
     6841 tgaggttgcc aacttgggtt acttttccag tccatttttt agagttgtct ttgcggtcaa
     6901 tcacttcgac tttttgaccg atttttaact tgtcacggtc aaattcacta atgttacctt
     6961 tgactaacat ttttgatttg tcgataattt ccataaaagt ttcattttct tttttggatt
     7021 ttgattgatt tggcaaatca gtatttagac taacaatggt tcctgcggtg tctgacttaa
     7081 cggtgtcata ctctagttta cctttttccg ttgtggcagt agcattagct ttatcgagtt
     7141 cgatttgagc ggttttgaca tcgctatctg ctgttttggc atcgcttagt gcttgggata
     7201 cactgtcttc tgcgctgcga atttgctcta gtaagctctc atctggtgca gtgttgtagc
     7261 gagattttag ggtgttgatt tcattgacct tgcgattgta ggtttcccac ttcaatgctg
     7321 cattggtttt agcaacttgg agctgattgg ctttggtttg aacatcaaat tctgaacttt
     7381 gagccgttaa ccgctgtgac gtttcatagc taaacaaggg ttgtcctact ttgacaacat
     7441 cgcctttttt aacaaagacc tctttgactt ctcctttact tgagtcgatt ttgactttgc
     7501 tgctgttgtt agctgttact tcgccagcta aggtcaagct gatatctttt ccttgttcca
     7561 tggcttcttt tatggttaag gcttttactt tgttgacact agagacaatt tcttgttgtt
     7621 gatggttcat tatcaagtag ctaccaccaa ccacacaggt caacactcca gcactcaaca
     7681 aggctaattg tttgcgcgtc attttttttc ttaactgaaa catactttct cctcaatagc
     7741 tattttttct ttttatacga tttttatggt tataccatac caacgttatc ccttttgaac
     7801 ggtcactagc aagacctact agtcatgatg acgcttaaca ccaacgatta atccgatgac
     7861 caacagtaag atgacaggta taatggatct tttttcattt tagcacttcc tttttggtag
     7921 cttgaaacac gacaaactgg ctattttagc gttcttttct tgtttttgga aaacaaaaat
     7981 catataaccg ttcgctcaca taagcacggg tatatgattt tgtacatttg cgagttagtg
     8041 tgtttggcta tttaggcatt atgataagtg agttaccatc ttaggcagac tgcctcatgt
     8101 catgcgtaac gtttgcgagt caccttatgc tctttgttgt aacccttagt ttttagcagg
     8161 agcgcctgat ccaccagcat cttttgattc catgccttct tcgtttcctg caggaatctg
     8221 aatcacgttt ccatcttttg tggtgtattc tgtaacttct tcgccatcaa ccacttttgt
     8281 ttttttgcta actgcgtcgt ctttgatgtc agacattttg atttctttaa cttcttcttt
     8341 tttagaatct ttttttgtgc cacaagctgt taaaaagcat gttgctgcta atgctaatgc
     8401 aggaatgact aatacttttt tgaatttcat gatgaaatgc tccttttgtt ttgatacctt
     8461 tagtttaaca gacgcatcta ctgtttttct aacgattatc tgttttttat ctgttttttt
     8521 gagattggct agcttttttt gtcctgtcat cgtagtatct gtgacgttag cgatggttac
     8581 atatgcttgt acatgatagg ggccaagtct aagatatcag ctagtagttg gttatggtca
     8641 ccgatcatat caaagaggag gtcttcagat aggacaccgc acgggatatc atcccaaggt
     8701 tggtttgcaa gccgaaacca ttcgtcacta ctgtaaaaat ttctaagtgt ggcatattcc
     8761 tcataatgct ctttaaaggc atctagggct tctatgagat ttgctagctt tgggctaaag
     8821 gcctcatagg tttgttccat tttttcaacg attaactgat cttgctttgt catgggttgc
     8881 tcctttgctg gttattacct ttattttaca ccgaaatgct agcaattgtc atgaaaaaac
     8941 ctctatttga taaaagcata catcatccaa aaaatgtgct cactcaataa atatagggtc
     9001 atcattttta tttaaagatt gttttgtgac cttgattttt aatctttttc tccttaaaat
     9061 gacattattg acactcttgt ctgttaaggt gactatcatt agataaggag gccaagatga
     9121 cccatcgttt ttttctcacc cctctttcaa ccctctggcg ccgtctgaga ccaaagcgtt
     9181 actccaaaaa agttttggct gatgagccta ctagctatca gccaccggca gctcatggcc
     9241 cgtgcgacga tattcatcag ttgcttgagg acaagagctt atcagacgat tatctgattg
     9301 ctacttctgc gatgagacac ctctggtact gggggtatag tcagattggg tagttagagt
     9361 ttctgactcc caatcagcta tgttaacgga ctatcactga taacattcac gctaagcctc
     9421 attctagcta ggcttagcgt gaattttttt tgctgactgg tttttaaata ttaaagactc
     9481 tatccttatt tggatagagt ctttagcttt atgacattgc cctagaccat cagtatagga
     9541 cacgtttcca ttatcggtgt tttgaaaagg ggagtgatgg ctagggctgt ctttttaagc
     9601 aaccttaggg aaataaactg gcaaccctct atttttgggc aggttgtttt tggttaggtt
     9661 ttgcaaactg ggctaagata ttggcaaatg ctttgtcttt gattttgaca tttgctttat
     9721 caagagcttt agcgatgact ttgttttgga agtcagggtc ttttaatttg ccagtcacga
     9781 tgatgtcttt caagcgtttt tggtacgctt tccagtctgc ttttttagtt gcttttttgg
     9841 tgactttgat gatatggtag gtgcgttttg aggtggctgg atcaagcgct gtgatgattt
     9901 ctgatctgtt cccttctttg aggcctgatg cagctctaac tacttctgct ggtagggttg
     9961 tttcgcctga gtcaaacgta taggttgttt ttttatcggc tgcagtggtt ttttctttgg
    10021 caatagctgc aaagtctgcc ccttcagctt tgacggcttc aagcgctgct ttggcatcct
    10081 cttctttttc aaactgcatg atttctgcgg tcatggttgg ggtataagcg tcataggcct
    10141 gacggtagtc tttttttgag atggtttcgt ttttggcttg ttctttgacg gcatattcga
    10201 ctaattttgt gaggcgaatt tgttttttat aggtttctgg cgttaagcct gattgtgcta
    10261 ggactgtctt aaaggatgta ccgtattggt ctgcggtttg tttataggct ttttcaacct
    10321 ctttgtcaga gactttgttg gcatattgtg tctcaaaaac gcggctaatc accaagctta
    10381 acatggcttt ttgtgcgagt tctgtgtttt tggtctcatt gtagaagtca ctgacagtga
    10441 tggtgtctcc tttcatcgag acgagtttgg tgttgttgtg tgatgattga caagctgata
    10501 aggtcacgac tgtcgccagc gttaccactc ctgtaatgag tttattcatt tgtttcatgt
    10561 ccttttgagc ctcttttctc attaataatt actgttatct tatatcatta gtcttaaacg
    10621 tagcttaatc ttgctttttg gtgttgctgc tcgttgtgac tgttcgttag aaagccactg
    10681 tctttaggat aggttaggtt gtggtgtttg gctgtagtca tgtatgaaca gaatctgacg
    10741 ttggctattt ttgagtgttg ttttcttgcc acggtatggc tagaataact ctcaaaaatc
    10801 gtaaaaggac tgagtcccat ctctacagaa ctcagtcctt taccttggca tcttagggaa
    10861 gtcatcatta gtaggcgttg atgacctcct ttatcaatgg gtgacttttc gatggaaaca
    10921 gtctgctcca tgagacaaac acttgcttag gtcggcgtga aacttaaaag gtagtggtat
    10981 tttagaaaca cggtcgtctt aaacgagtgg tgagggggca aaagctactt tgaccgatca
    11041 atccaaagag ttgatttgtt tttggtaagc ttctatcata ctcctgacat tatcatggtt
    11101 gaggtctagg ttattatcaa aagaatagcc taaaatggtg tgcgctctgg tgtctcctga
    11161 tacgatgata aatccagcag gagacaaagc atagatgtat agctcaccac ctgagtgatc
    11221 tgtgtctgat ggatagctta actgctgcac gcgcataggg gtttttgttt gtgtgttttc
    11281 ggcacaaaag gtttcagcta tgcggcgtgc ctcaggttct gttctaacga aatgcatttc
    11341 catactaagg tttgatgcct acaacagcac tttggtaacc gttgaagccg cctgcgccgc
    11401 caccagtacc aagagctgaa gggtttagtg cgtcaagacg gaagaagccg tcagagactc
    11461 caccccaacc ccagttaaca tggtagaagt tacgtccgtc agcaccatcg ataacaaagg
    11521 catgtccgcc tactttaccg acaccttggt agtatactgg ttggttttga gataattctt
    11581 tgtcaatttg tgcttcccaa tcttgtttgc taaagtcgcc acggttgatt tggtgaacag
    11641 attggttgta gccaaagttt tctttcaagg ctctttgaac acgagagcta cctgcagaac
    11701 cactagatgg accataatcc atgtctactg aaataccaac atcagccatc aattctgaaa
    11761 tcgccatttt ttgaacgtta gattctcttc cgctataagt aggtaagatg ttgttccagt
    11821 tgtattgtct agtagagata gctgcaaaca agttcttagg atggttgaaa tatgggttat
    11881 ttgagcttag tgtgtaagtg tagtctttca accctttgtt agggtaatta tgatatttca
    11941 taatttgagc agttgcagta gcaacacatc ctgtagctgc atgttgacct acaaaagatt
    12001 gttcacctgg ttttactttt tcaataacag gtgtcaatag gttgtaaggg ttaccttgat
    12061 tgtaatgaat gccttttgaa tcaaggagag atttaacaac tggttgttta atctcagcgg
    12121 taccagcata agtagtgtct aattttttgt tttctttgat ttgttcgaca taactttcca
    12181 tgaaggaagc aatgttttct ttaccgttag cgtcaaatga tccgctggta gagtatccta
    12241 gaatttctgg agaacgttta tctcctgaaa cgataacaaa tcctccagta gaaatattgt
    12301 aaacatacat attagagcca gaaagttctc cacctaagtt aactttgtca agcttaatat
    12361 cttctgcgct tcgtgcacct gctttgatag ctgctgattt ttggataaat gtgatagcgc
    12421 tatcttttgc ttctttttcg ttacgagcaa agttttgatc ggcaaatact gggttagcaa
    12481 gaacaaatcc acctaatgct aaaagactta ataatctgac acctaatttc tttttattca
    12541 ttttttttat acctctttca aaataagtta atctactgca tttgctttta acggtacatt
    12601 ggacacacct ccttacttag ctgaatcgta tggttatcat acgatgtcgc tgataccatg
    12661 aatggtaata gacaataaca cggttagttg acactgacaa cccaacccaa ttattctcat
    12721 ctcatgtgag cctaattggt tttggtcaaa agacgctatg agtcgttgca cttatcatct
    12781 tttggttgat ctcttatctt ctgccgtatc tactaggcag actgataggc aagatcagct
    12841 agcaaacaat aggttgtgct tgacagtttt ttagatgata tgggaccgtt ctcattttgt
    12901 taataactga ttctgtgata aggatcgtga tagggtccac aacaccaagt gaaagtcctt
    12961 tgtctttttt tgggttgtcc attagttgac tcgtaggctt tttcctggct gatttatctc
    13021 atttttactg acaattagcc ttttagttac tattgtggct agtagatgct catttcagtt
    13081 gacaagaaac ttaaaaatac tgataatata aacaaaatga ttcttttgtt tgtcaatgct
    13141 tttattgact tctcattttt atctactacc attttgcaaa aggaactaca aaaatagtaa
    13201 caataaccac atagtaggcg cctcctttta accttatggc tatatcatag ctgcttattt
    13261 tgctaaccca ttattttgtt acgtattagg tacacacgta acgtattttt aacatctatt
    13321 agattagaaa ggtttaacat atgacagttg ataaaactat cgcatctggc tattgacctt
    13381 atgcacctat cataagcgac tatcatccga aacattcaac ttgttacgta ttaggtacat
    13441 gcgtaacgta tttttgacat caactaggaa ggcttgacat atggaaattg gtgaaaccgt
    13501 tgaattcatt aggcattcaa aaaacatttc gattaaacaa gtttgtggtg attatctcac
    13561 taggcaaacc tattatcgtt ttattaaaaa taatcttgac atttcttcga aaaagttact
    13621 ttatatctta gacaacttga atgtcaatgt tgatgagttt ctctttatta gtaataactt
    13681 taaacaatac aaagaattta ttgatatgga tacggcaaaa cattattttg aatgccgaaa
    13741 catagaaggt ttaaatcata tccttgattc ttataaagat agtaagtcaa caaaggaaaa
    13801 gaaccttttt gccttggtca aggtgttatt agcaactctt actgaggaag actgtctgac
    13861 agagcggact tatttgtcaa actatcttat taatattgaa acttggagtc actatgagac
    13921 tgtgcttttt aataattgta tgtttatttt tgagtcttgc tttattgaga tggtgttttc
    13981 aaaagttatt ttgaacctcg ataaatacaa taccctaagg tattatggga atgaatcgat
    14041 tcggatgttt gtcaatatgt tgattttgtt tattcagcga caagagtatg ataaagcttc
    14101 tgagattttg gcaaaaattg aagattatca gctaaatgat gattgcttat atgaacggtg
    14161 ttgtgtgtct ttttttgatg gcattattgg cctcataaat ggtaaagagg gggctgagca
    14221 aaagtgtgtg cagatcttgg agatcttcca attacttaat tgcaaaacga tccatcatat
    14281 gtttcaaacc tacctagaag ccattaaaca taaactgtcc tgaggctctt taaaaagcta
    14341 acgctcttat ggtgttagct ttttgatttg gtatcttaat aaatggtgta gtttatctca
    14401 acagctccag ggcgattttt tcaatttgct ttttactttt tgacaaatca taaaaagcaa
    14461 tgacgacaat cattgctttt tctagtattt ttactttcta tagtcattgc tttttttgat
    14521 gtaaaaagct aggcctagtg agcagaggtc tagccttttg gtattatttc tgagtaggtg
    14581 taccgttatg gtagttaatg gtgtagccat tagctgtgtt gtaaactaat actttctcgt
    14641 tgatggtatt atcagaagat tgcattgata ccacgacagc tcttggaatc aactcgtctg
    14701 cgttatagat tggagcagct tcataataaa gatagccatc acgatttgct tctaaccatt
    14761 cttgagctct ttgttcggta tagcgcatgc cgcctttttg gtcacgacct cctacatttt
    14821 gggtacgtgt ccctgtaacg gcattgactc tgagtgcatc tccaccgaga ctatctgcaa
    14881 tgagatgact tctattccag aaatctccga cataagatag accatttaac cattcaattt
    14941 tatatttgac atgattaggg tttccagtcc agcctgcggg gttttgattt ttaccgaaag
    15001 attgtctaac accgtagcta ccttcaacat tggcataagt caatgtacct ctagcagtac
    15061 gcgtccttcc taactcatct aatttgctat agagaatatc tcctgcttta ggaaagagtg
    15121 ctggagtgat ctgactagta cctaaggttt tgtaatagtt gggactgtca ttgaatgtcc
    15181 aagctaatgc ttcgtttagg tacttgcttg cgccatcatt tagaacaaca tcatttgaga
    15241 cctgtgtttg tcgtgccagt gcagtatttt caagtgtgac tgttgttaca gccattgtgg
    15301 ctgatacaag agctaccatt gaaaatttta ctagccgaca ttttttagaa aaaacccgtc
    15361 ttgatccaag tagattcata tgcttgtcct cttttctaat ttcgctcact aaccatagta
    15421 tacgcttact taactagttt atcaatagtt tttttaaaaa atatgaaaat taaaggagat
    15481 agtaaggaga aaaaagaagg cgttgtcttt ttgttttgcc atactaatat catttttgaa
    15541 ataggtgctg tgtgtcacct agaggtggtg attgtattta ggcctaggta agatggttac
    15601 tttactatcg tttctttgac ttttaccaag taggggattt cagtagtcaa cacctcttaa
    15661 aaaagaacta ttccctcttt agctgttgta gaggtttctt aaaatctttt atgttacaat
    15721 aaagaaaaaa aggaggtttc acatgtcaac tgaccatcaa ttacgagaag tttcttatca
    15781 attactggct gagcgagggg tttctttaga agctattgca gagctggtgc tttttttgca
    15841 gaatgattat attcccaatt tgaccatggc agaatgttta gagagcgttg aggcggtgct
    15901 tgcaaaacga gaagtgcaaa atgctattat cactggggta gaattggata aattggctga
    15961 agccaaccag ctgtctgagc cactccttag tatcttgaaa accgaccaag ggctgtatgg
    16021 gattgatgaa atcctggcct tatccattgt taacctctat gggtctatcg gttttaccaa
    16081 ttatgggtat ctggacaaga caaaaccggg aatagttgac aaactcaacc acaaagatgg
    16141 ctactcctgc catacctttt tagatgatat tgttagcgcc attgcggcag cagctgccag
    16201 tcgtattgcc cacaatgacc ccgctaaaag tgctattacc aaccaacaat aagcaaaaca
    16261 agtctaggaa gtgactccct agacttgttt ttttgaggtt atctggcaaa taagaaatct
    16321 ctttttggtt agcctatcga ctcgtaacat aggcatcaac agcaaccaaa gccgctgcta
    16381 catcttctgg actgataaca aatggcattt gatggatggt ttcgcctgcc atggttgctt
    16441 gacggccaat ttttaagaaa tcctcttgag tagccgtgtc taaatgcatt tctttgaggg
    16501 ttgttggcat gccaatagct tggtaaaagt cgatgtagcg gtcaatttct tcacgcgaac
    16561 gattttccaa gaagagttgg gtcaacgtgc cataggcgac tttttcacca tgggtaaggt
    16621 gatgaatagc acctgtcagc gctgtaaagc cattgtgaat ggcatgtgca gcagccagac
    16681 ccgcactttc aaaaccaagc ccactaagaa gtgtattggc ttcaatgaca ttttccaagg
    16741 ccggggtcac gacttgtctg tcacagctag ccatcgcttt taggccatct gcaaacaagg
    16801 tctgctcaca ggctttggca atggcaactc ctgccaaggt ttgattgcca cctgccatgg
    16861 tgtctccatt tttttgcata acagcacgcg cctctaccca tgttgctaac ccatctgcaa
    16921 tccctgacgc caataagcgt tttggtgcct gacagatcac ttgtgtgtca accaatacaa
    16981 gatctggatt ctttgaatag aaaatgtatt tttcaaaggc tccttcatcg gtgtaaataa
    17041 ccgataaggc tgaggttggg gcatctgttg aagcaatggt tggggcaata atcaccggaa
    17101 cagcaagtaa gtcagcgata gccttagcac tgtcaatggt ttttccacca ccaagtccaa
    17161 taataacatc attgccattt tccttggcaa tggcaaccac gcggctgatt tcattatctg
    17221 aggcttcgcc attaaaggct acgtgaacag gagtcatgcc attatctatc aaatagcttt
    17281 caaatctttc tccgacgatg ccatacacca cgtcatcaca cagtaaaatg gggctatccc
    17341 ctagttgttt tagggtttta acattggtaa acaaggcatt tttaccttga atgtaacgag
    17401 atggacttgc aaatactttc atcgttgaac tcctttatct gtgattccta atgatgtgat
    17461 tactactgat gctatttctt aaatgctctt gcggtgatga acggcttccc aatccttgcc
    17521 aaaatcgtca accgcttttt gaatagatgg catggcaaat cctgcttcaa acacatctgg
    17581 gccagcagtg atggcttgtg ctcctagagc aaaggattta ttaacctgag ccacattttt
    17641 aaagcttgct gccaaaatct tactattagc attctcgcgg ttaatagctt ctgctaattg
    17701 ttctatgaca gcttctggat caatattaag attttccata cggttatagt aaggagccaa
    17761 ataatcagcg ccagcttcaa tggctaatag tccttggaag gtcgtataaa tagcggttgc
    17821 tgtgatgtga tagccttcgg ctttcaaggt tttaatggct gcaaggccct ctgtggttac
    17881 aggtactttg acatacacac tatctccaca ttgcctgcgg atttcagcag catcttttaa
    17941 gatgccttcg taatcttggg cgatcacttg aacatgaata gaagccttgt caccgataat
    18001 agcacggact tctcgaatcc gttcaaagaa atcaatctca ccttcttttt tggcaataga
    18061 agggtttgag gtcacacctg cgagaggcaa aatgtgatgc cattttttaa tagcttctaa
    18121 atctaaagtg tctaacatgt attccatact tattttctcc taaagtgtgt gttctgtacg
    18181 ttcaataatg tcatcttggg ttgcttttga gagcacattg aagaaagctg agtagccggc
    18241 aacacggaca atgaggtcgc ggtgcttttc aggatgtttt tgggcatcaa tcaaggtttc
    18301 acgtgacacg acattgtact ggatatgata accgtgtagg cgattaaaga aggtacgaag
    18361 taaggccatt aatttcagtt tgtcttcttc tttggccagg gtttgtgggt taactttttg
    18421 gttgagtagc actcctccga caatctcatc tgttggtaat ttagcaacag atttcaatac
    18481 tgaagtcggg ccttttttgt ccatgctgtg ttctggtgaa cagccttctg ctagtggtgt
    18541 gcctgcatgg cgaccgtctg gtgtcgccaa ggtccctttt ccttgtccga cattggctga
    18601 gattgatgat gtcccagaat agcggatacc tccgattggg ccacggccat accgggtatt
    18661 tgggtatttg gcaatttcat caatgtaggt gtcgtaagct tcgacgacta aactatctgc
    18721 gtagtcatca tcattaccat attttggtgc gtcattgatg agcatttggc ggatgtcttc
    18781 tccgcgttct ccagcaaagt cactttcaag ggccttccag agttcctctg gggtcaagcg
    18841 accttcttca aacactaatt ttttcagcgc tgctagggag tctgataggt tggcaatacc
    18901 aacttgaagg cctgagatat agtcgtaaac agctccgcct tcttttaagg tcttgccacg
    18961 accgatacaa tcatctgtca aggctgagca aagaatatct ggtacttcac gttcaagacc
    19021 gaggtcaatg gcattttcaa caatgacgct catgcgggta atttcgcgca gggtggcatc
    19081 ccatgctgct tttaattctt cataagaggt catgtctttg aagtgaccgt gtccttttgc
    19141 aaagcgcttg cctgatgctg ggtcaatccc gtcattcatg gtaatcagca agattttagg
    19201 gaagttgatg taactcatcc ccgtgcaacg gtagccccat tttccaggaa ctgctgtttc
    19261 cacacagcca atggctgagt aatcataagc atcttcttct gagacacctt ttttgatgaa
    19321 agatggaatg atgatttcat cgttgttcat ggctggcata ccaaaaccaa gtttcatgac
    19381 ctcgatacat tcgttcataa aggtattgtc taggcctttg tggtaacgaa cagtcaagtt
    19441 aggttgtggc aatttggttt gagccacact ccgtaggaca aggtaagaca gtgggttgac
    19501 cgcatctttt ttatcgcgtg tttgaccgcc gattgtcacg ttttggtaaa gtggactacc
    19561 tgctgatgag aaggtgtggg cttggctccg tactttatta atggtcaagg tcttaatcca
    19621 gaggttggtc aaacgttcaa caattgtgtc ttctgtttca cggccagcct ccaaatcagc
    19681 tttgacataa ggatacatgt actggtcaaa gcggccataa gatagggaat gcccatttga
    19741 ttcaatttgc aaaatacact gaatgaacca gacagattgc acagcctctg caaaggtttt
    19801 cgctggttcg taaggtactt tatcacaaat gcgcgcgatg tctaacaatt ctgcttgacg
    19861 ttctggttta gccgtttttg ctagttctct agccaacttg gcatagcgtt tagcataagt
    19921 tttgactgca tcaatgacaa taaaaacaga gtcgtaaaaa tggtatttgt caatgttttc
    19981 aggaatggtc aaatcaagcg cagctttggc agctcgtgcc cgttcttcaa atccctttaa
    20041 gccatgctcc aagagttttt ggtaattaac cgctaaatga gcatccccag agttcatctt
    20101 gccttccatg ccaaagaaac ctgtttccat gtacacttgc acttcttctg gtagcaagac
    20161 accgcagcga gcacgcaggt tattgttttc ccagaatggg gcaatgtctc ggagctgttg
    20221 cttggtttct tcggtaatgt agaagacatc cccatctcgt ttttcaaaaa gatcaagttc
    20281 gttgaggaca aattccagag tgtattctgg gaaaatcggt gcatccttgt ttgaagaggc
    20341 ttggttacca gcaatgaggc tttcatcctc aatatagatg gtcatgtttt ccaaaatagt
    20401 ttgaagcatg taagcgcgtt tgaggtttgc tggcttattt tggtgttttt gataggcttc
    20461 agtggctaaa atagcacgct cagcatcaat ataaggtttc ttgtctaaca cagcttcacg
    20521 atagtgagtc attctgtctg ttaaatgtcc aaaataaggg ctttttgttt cagtcatgcg
    20581 gggtctcctt ctttcttacg aaattataaa cgtttctttc gtaactattt tatcatatat
    20641 taggactttt gcgtatcctt aaccataaga agagatagtc actttatttt gcactattgt
    20701 gcaatatagg cctgataagt cgttcttctt tttctaaaaa accacctcta actggagatg
    20761 gtctcaagaa tttggtggac gctaaatcat gactcttcac tagcttgttc attttgataa
    20821 gccatattat cttggatttt aaagaatggg aagtacacca acgttgacat gatgagtata
    20881 agaatttgca caatagctcc ttgccagcca ccaaccatga accctgagat aatggctggt
    20941 gttgaccacg gaagggtcac tcctgcaaag ggctgcatga aaccaatagc aatggcgcca
    21001 taaactgtga gagctgccaa gaccggaacc aagataaatg gcaagaacat gactggattc
    21061 atcacaattg gaaaaccaaa gacgactggt tcattaacat taaagagggc tgggaaggct
    21121 gcaaccttgc ctaaagcctt gtattgtttg gatttagccg caaagatcat agctaccact
    21181 aaaccaaagg taatgccaga acctgataga atcaagaaag agtctaaaaa ttgttgggtt
    21241 acaatatggg cacccttgtc tagggataac tcacctgctg ccatcaaggc cttattggca
    21301 tctagatttg ataagagaag agcagtgaca attccattga ccacagattg cccatgcacg
    21361 ccaaaccacc aaagaaagga aataaagaag gcaataccta gtgcgccata aagagaaccc
    21421 gttaaccctt gcagcggtac ctgaatgaca tcataaatca tttcaataaa ggtgccacca
    21481 cctgttactg acttggcaat aatatacaca agcattgaca aggtaaagat cacaaaggct
    21541 ggaatcatgg cttcaaactg tttggcgatg gcttgtggca cttgatctgg cattttaatg
    21601 acgatatgac gacggataaa tgttgtgtaa acagctccga ccgttaaacc aatcacaata
    21661 gcaccaataa tcccttgacc accaaaccaa accttactga tagcatctcc aatagcttca
    21721 ccttctgctg gaacataaga tgatctcaat aaaataaaga aggctgacaa ggatagaacc
    21781 cctgaaggga gaggttcaac acctgagttt ttagcataag aatagccaat tgcaaaacag
    21841 gaaatcaacc ccataatagc aaatgttcca tggtaaacct gcataaaggg ttctgtccag
    21901 tcagcaccaa acacactagc aatggcatca ttaacccctt ggaaaggaat ctgcccagca
    21961 atcaggaaaa gactccccac aacggtcaaa ggtaaaatgg ctaacatacc gtcttttaag
    22021 gcaatgatgc cgcgcatatt cacaaatgtc atgattggct tgatgatgtt ttgcatattc
    22081 atttttgcca tgattgactc ctattcttta acaaggctaa gggctaaatc aagcaccttg
    22141 ttgccgtcta acattccata atcagccatt gggataactg caatagggat atcattgtct
    22201 ttacaaatag cttctgattt atccagagta taggcaacct gtgggcctaa aagtgccaca
    22261 tcaagtaatg gtgcatagtc cgctaatttc ccttgagcat aggcttcaat ctgacaatca
    22321 atgccttttt tttcagcagc tactttcatg ttgttcacca acataccggt tgaaaatcct
    22381 gctgcacaaa acaatccaat tttaatcatg tcaatctcct ttttagtcat gaaaacttat
    22441 ttagttgcca attctttacg aaggtcaata atctctttga tgagattaat ttctgtaatg
    22501 gtcgtcatca agtgatcctg tgagtgaaca aaaagagctg taatctctga cttattacca
    22561 ctagcttctt gggcaagaaa ctgggtctgt aaattgtggg cttctaataa ggcatcatct
    22621 gctaaggcca tttctttttc actagtggca taatcgtcct ctttagcaca tttcagagct
    22681 tggtagatat gttgtttggc atcgcctgca tttaaaatta agcccataat gatttggtct
    22741 ggtacaataa cttgcattgg tgtctccttt ttttcttttt catgtgatgt aacggcaatg
    22801 agtctttttt tcgaaggtga tgttattgtg tttgtaatcg tttacatttc gttggtaagt
    22861 ttattgtatc atttttgttt ttagggtcaa tatattttgt gctatatttt ggttaatgca
    22921 cttttgtgcc aatacattaa ctgcacattt gagcaatctc tgttttatca acacatcaaa
    22981 caaaaaaagc cctgaccgtt tggtcttggg cctctataaa tatcatagta tttttgaatt
    23041 tctattaaag aagaacgtta ttaagatcaa tatcttcatc taacgctaaa acagctagca
    23101 tggtctcttt atccgtcact agataattga taaaacctgc ttttaaggct gccaatattg
    23161 ccttagcctt gtgtttacct gttgcaacag ccattgtttt ggggacacgc ctcaactgtt
    23221 ctagtgaaat accaatagtt cgatcctgta ggccagtgta aactggctga cctgcctgat
    23281 caaagaaacg gcaacaaact tcaccaacgg ctttttcata tttgagttgg tcatgatctg
    23341 agctggttaa taaatcacgc cattggctct gctcaaggct attaggctcc ccaccaattc
    23401 ctactaaggc aagatctaac tggtcccagc ttgttaaaat gtcgttaaag tatttagatt
    23461 gtaagattcc cttagccaag tgtttgtctt cttgaatgac catagcgttc ataaaagcgc
    23521 tattaccatg aaagatgcga gccaagcggt aaaccagggt attgacatgg tatttggcat
    23581 taatatggct aggtcctcct gccaaaggat aaataaacac atctttcatc gcttttggat
    23641 ttaactcatc catcaagcaa gaaagagtcg ctccccagga cagaccgatc ttatcgccat
    23701 ctttaacaac atgtctaaaa acctcagctg ctgttttagc aacatttgtc aaggtatcca
    23761 ttggggtatc ttcaacctgg ttgggcacaa ggtctagttt ttccaagcca tactgctgtc
    23821 gcacgtattc ttctaaagca aataaatcag catcatagtc ggcaatttca atccgaacaa
    23881 tgccttcttc cttggctttt gctaacatcc gacaaaccgt tgttcggtag atattcattt
    23941 cctttgaaat caaggtttgg ctcttgcctt gaacataatg caagtaagcc accttggcaa
    24001 ggagccgtct gcgttcttct ttcatctagc cacctatttt ctaagaaaca aaatcaagaa
    24061 caagaccact agcacttaat aactcttgtg tttgcttgtc tagtgcttgg tctgtaatga
    24121 cgcgattgac atcagctaat gacaactggt gtaccagact ggtttttgaa aacttgctgg
    24181 aatcggtcag aatcaccact tcctcagcag catctgccat gtaacgcacc ccttctgagc
    24241 gcatcatgtc cttgcccata aagccaagat ctttgttgaa accgtctgtt ccaacaaaga
    24301 cacgattgac atgaaaaagg gatatcattt ctttcaataa aggaccaaca gtcacctctg
    24361 aattgggctg gtaataaccg cccagtaaaa tgatttgaca gctactatat tgacgaatgt
    24421 agttggcaat gaagcacgaa ttggtaatga ctttaatatt tcgtttggtc tggcaaagca
    24481 cttctgccaa aagggcacag gttgagccag attcaatcat aatggtatcg ttgtcttgta
    24541 ccaattcagc tgctttttct gcaatccgtc gctttatgtt gtaattgtag gacaagcgta
    24601 cattgaggtc atcgccactg tttagcaccg catagccatg ttcccgtcgc aacaagccct
    24661 tactttcaag cttatcaagg tcttttcgaa tggttacttt cgaaacgtct aattgctctg
    24721 ataaactgtt aacatctatt tttttcttct gggaaaccag ttgaataata cgttctaatc
    24781 gattcatcat tcacctccct ttcattgtac cagttatttt cttaaaagaa aagggatatt
    24841 tactttcatt cgtaattgat ttatttacgt ttatctggta tgatagtttt acaacgaaag
    24901 gaattcacac ttatgactga tcgcggtatt gttttcaaca tccaacattt tagtattcat
    24961 gacggtcctg gtattcggac aaccgttttt ttaaaaggtt gccccttgag atgtccatgg
    25021 tgtgccaatc ccgaatccca acaaaaagcg cctgagcaga tgttaacaag tgatgggctt
    25081 aatactaaaa tagttggaga ggaaaaaacc gtggacgagg tgatcgaaga agtccttaaa
    25141 gaccttgatt tctacgaaga gtcaggtggg ggcatgaccc tgtcaggggg ggaaatcttt
    25201 gctcagtttg actttgcctt agccctgtta aaagcagcca aagcagcagg tcttcacacc
    25261 gcaattgaaa ccaccgcctt tgccaaacac gagcaatttg tcacccttgt tgactacgtg
    25321 gactttatct ataccgattt gaaacattat aatcagctca gacaccaaaa agtgactggg
    25381 gttcgtaatg acttgattat caagaatatt cattatgcct ttcaagctgg aaaagaaatc
    25441 gtcttgcgca tccctgttat tccccaattt aatgattccc tagacgatgc taaagccttc
    25501 tcagagctct ttaatcagct tgagattgac caagtgcaac tgttaccttt ccatcaattt
    25561 ggagaaaaca agtacaaact tctaggtagg gagtatgaga tggctgaggt caaggcttat
    25621 catcccgaag atttagcaga ctatcaggct gttttcctca accataatat tcattgctat
    25681 ttttaatgtg ctaagcaagt gaggccaggc tgtttatgcg ttgactctgt tacaagctaa
    25741 tttagtgcac ttggtttgga gatcgttgct acattgcctt tacctttatg cttttttaaa
    25801 gctcaaacca gtatgggctt taaaaaagct taccaatcag attattgata ctacaaaaaa
    25861 ggctgggaat actcccagcc taggcttttc caagcaagct tatcatttct accaatcttg
    25921 acctagaata aattaatcag tgctaataca ctctttgcta agagctgatc aaagatgtag
    25981 ataatcaccg taaagaaagc tgtgtactca agaactgaga taaaatcttt ccaacgttgt
    26041 ttacgatttg gccatgttgt gtcttttaag actttaaaag tcccgctaat gaatcccatc
    26101 aggctctcct ttttaacgtg tttctttgtg taaggtatat gttttgcagt atttgcaaaa
    26161 tttatttact tctagacgtg ttggtttagg cgtgctactc actccgatag agtagttacg
    26221 actgccacat tcgacacacg ctagactcgc ttttttctgt gccataacgc ctccgtaact
    26281 attattttaa cacgatctct aaaatactgc aagctatcta aaatagtcaa caatctcttt
    26341 ccaaatagat tgggctttat cacgtaaccc tgactgatcg actgcttttg atagtgattg
    26401 cgaagcttct tgtgctgatt ttcttaaacc atcaataata gattgagtat caactcctga
    26461 ttgattacct gtttcattga ctccataaac agctgaaata ccattttgag cgtaggcatt
    26521 atctacatga aattggctgc ccttggtata aggcaaaatg taagatgcct gagtgctaaa
    26581 aatagctgag gccgtgcctg cacttgaatc cgttagataa tgattttcat cggtctgatt
    26641 aaatcctacc cattgactaa taacaacatc tggcgtataa ccaataaccc actgatcgcc
    26701 tgctaagtcg ggattgaagt tggtttctgt cgtccctgtt ttaccagcta gtgtatagcc
    26761 atatacgtta gcattgactg ctgttccatt tgaaaaggta cctagcatca tggctgtcat
    26821 cttatctgca acagactggc tgacaacacg tttagcctta tcagtaaagg ttttaagcac
    26881 ttcacccctg gcattttcaa tccggttaat caagtgcgca ggatggatta ctccattatt
    26941 ggcaaaggca gcatatgcct gagccatctc caatggattg gttgtcacgc tgccacctaa
    27001 agctaccccc aactcttttt tggcagagct catatctaac ccaaatgttt taccataggt
    27061 aaaggcttta tcgattccga tatcgttcaa tgtagaaact gctggaatat tataagagtt
    27121 tgctaatgct tgatacatag gaacatcttc tgattcataa tttccataat tatgtggctg
    27181 atagccatcg aaatcttgaa cggtatttgg tagttctttt tcaattgacc atcctgaagc
    27241 aacggctggc gcgtaaacca cgagtggttt gattgttgat gcgggactac gttttgcttg
    27301 agtcgcatag ttaaaacttc tgaaagtcgg attttcacta ctattcacac gaccaatcag
    27361 acctctaaca cctcctgttt taggatctaa agcaacacta gctgcttgag cagagctacc
    27421 gtcataagct gaaacaggaa atagttcatc gttgttaaaa gtcgtctgca tgccagtttg
    27481 gtaattttga tctagctcag tgtaaacttt gtatccatta ttaacaatgt ctttttctga
    27541 aagaccataa gttgctattg cttcactaat aacagcatca aagtaggatg ggtatttgta
    27601 gtcatctgtc ttaccaacat aagtatcagc taagcgattt tttagcccta ctgctctagc
    27661 ttgctgagct tttgtttggg taatcttttt ggcatcaacc atcgctccta aaacagtatc
    27721 tctacggtga gtagcatttt ttagagaatg gtaagggtta tatatttcag gtcctttgag
    27781 catacctgct aatgtggcag cttcatccag tgttaagtta gcagctgtgg ttccaaaata
    27841 tttttgactg gcatcttcaa ctccccaaac tccatttcca aagtaggagt tgttaaggta
    27901 catagtaaga atatcttttt tactgtattt tttggtcaac tctaacgcca aaaaaaactc
    27961 tcgggccttt cgtttaattg tctgatcttg tgagagataa gcatttttag ccagttgctg
    28021 tgtaatcgtt gagccacctc caaagcggcc cgccgtaact accgccaata agaagcgttt
    28081 aagattaata ccgctattac tgtaaaaagt cctatcctca gtggcaataa cagcattctc
    28141 aagatcatct gaaatagcgt tgagctcaac ataactccct ttttgaccag ataaactgcc
    28201 tgcatactct cctttgtgat cataaataac cgttgtagcc ttcaaggcat cttgtaaatc
    28261 agatacttta gctgtttttg ataagtaaaa caagtatgat cctaagagta agacaagagt
    28321 tccaatcaga atcattagca gttttccgat gtgatagcgg cgccaaaaac gccgaattgg
    28381 acgttgagga gacggcaaaa cagcttccag cttttgcaac caagcgggcc gacttttagg
    28441 gcttccttcg taggctctac tgcgttgcag agctgttgca gggtcttgtt ctgagttttt
    28501 ggtagctgat gagtccaaat gattggcatt tggcgaatac tgcttttgat tgtgttgtgg
    28561 cgttaaacgc gttttttgat gcattaagaa ttgtttttcc tgatatgctt taggaaaaaa
    28621 tttcttttgt aaaagttcta gaaatctcat aacgttatta taccactatg atcttaaagt
    28681 aaccttgatt aggtcatcga aatatgcttt gaataagcca caccatccac ttgaaagagt
    28741 agtccttgtg gtccaccgtg atgtgcaaat tccgtttgaa tcgattttcg agcagggtat
    28801 ctgccattaa agcgctcttt aatcattttt tccatcacag gtatgttcca aacgtctcga
    28861 aatagacaat ccatttgaac aactgcatct aatgtgagcc ccaccaatgc taatcggcgc
    28921 tccatctcgt caaaggctcc attaatctga ctttcaatgt cttgtccaac attgccgaca
    28981 caatagttta aataatagaa atctcctgct tctacaaggc ctgtatgccc tctatcttcg
    29041 ttaacatcat aacgtctaat tgttttcatt gtttttcctc tattttacga ttatgttttt
    29101 atcacaatta taacaatttt tcttaatatt ttatattaaa aacctttggt tgacttcttt
    29161 tacgatagag aaatacctat cataaggcca aactaatccg tatttttccg atacgtcgtt
    29221 caacctcatg gggttgtttt gaaagaacat acctgtttga ctcatcgtct taggtaacta
    29281 tgtgttgata agttttatct tgctattttt tatgactgtt ccaacttcgc aacacgttag
    29341 ttgttttcta tttctgcgtt agcacctagt ttcatatcat ttctgttaca aactctatca
    29401 agaggtctta tttaagacac tttcttatta gatggattag caaaataacg tttttacctt
    29461 tttgagtggc acgttttgat tagaaacatg ctataatagc attgaattcc ttgcattaat
    29521 caggagctca cattaaacat agaaggacgg gtttaaccaa tgaataaatt ccaagctttt
    29581 aaagaaacct tatccgcaga aagtctaaaa gccatttacg atgagactcg cttggaggta
    29641 gctaatgacg agcgtgaagg tactgaagct ttctctgctg ctcttgccac ccaaatggct
    29701 atcaaccttg ttgaaaaata ccataactgg ctcaatgaag acaacaaata aaccatcaaa
    29761 ggggtttact gtcacactga aaaatccctt tgaagaattg acggtcaaag cattattaga
    29821 ggaacaattg ttaattcccc gtaaaattag gcattttctg agaactaaaa aacatgttct
    29881 tattaatggt cattctgtta actggcaaag ttgtgttaaa tacggtgatc aggtcaaact
    29941 tttttttgat cacgaagatt atcctgaaaa gattatcgtg atggggcagg ccgaaaaagt
    30001 aacctgcctt tatgaagatg agcacatcat tattgttaac aaacctgaag ggatgaaaac
    30061 acacggcaat gatccaacag agttggcgct gctcaaccac gtgtctgctt acacgggaca
    30121 gacctgctat gtggttcatc gtctggataa ggaaacaagt ggggccattt tatttgctaa
    30181 aacacctttt atcttaccaa tccttaatcg tcttttagaa aaacgagata tccatcgaga
    30241 atatttggca ctagttcacg gatccttaga cagtcctagg gtaacttacc atcatccaat
    30301 tggtcgtcat cgacatgacc gcagaaaacg tgttgtcgat ccgataaatg gcaagaaagc
    30361 tattactgag gtaactctag tcaaaaactt ccacaaaacg gcaagcttac tcacttgtca
    30421 attacaaact ggacggactc atcaaattcg agtccattta gcccatcaag gtcatgtttt
    30481 atttggtgat cctttgtatt ccaatggaaa aaaagattgt gctcgactga tgctccatgc
    30541 ttatcaatta cgtttgaaac accctctaac ccaagaagac atttgcgtgc aagctaaatc
    30601 agctacattt gacgcagtct taaacgctca aaaggctagg aaataatctc ctagcctttt
    30661 gagtttatct gttttcatag cactgtattt gagcgataac attgtttcta ctgttctttg
    30721 tggctttgca tcctttatgg ttgcttttgc aaagttactc ccgaaagtgg cttggtataa
    30781 tcaaattcat gtgttaatgc tgcctgccac accactggag aggctgtttt accagatatt
    30841 ttgaaaccat aagcatattt gacatttgca ccccccaatc ctccttctgg aactaaggcg
    30901 cttatgtcac ttccaggatc tggcgtataa agataaaaac cattgccttt gtcttcaact
    30961 ttactaattt tagctgtccg agtttcttta gaacggttgc ctttttgatc ttcaacttta
    31021 gtcgtaattg ttccatctga tgctagagac atatggatgc tcaaaccatt ggcttggcct
    31081 gtccacgttc ccaaaataga ctcaggaaag acagatggcg ctttgagttg attgtcctct
    31141 ttaacaacag taatattttt ggagccggac tggctgataa ggtaatgctg tccaactttt
    31201 tttacagtca cttttccagt caagtcttga ttaatatgtc cagaggtatg ctgctcagga
    31261 tctgttgact tgtcatacaa aaattcgtag gtagctgtga aatcaagcac gtaagttgtt
    31321 ttacccactt gagtcattgt tgtcaaaagg atagatggaa tattgagacg gctggctttt
    31381 cttgtatctg tctgaaattt cgcttttatg gactctttca atcccctata aaatgcgttg
    31441 ctagaccctg cctcaaagac gctacgtaag ttagatgagt cttgacctgt actgaggtag
    31501 tgcatcagct gatcaaaagc tgatactaat agctcccctg ccttgtcctc ttctaaaaga
    31561 tctgtaacta aaatctccag ggttgctcct tcttcaacat cagctagagc atatttttgt
    31621 gatcttaact caccatctgg gaatgttgtt ttcatataag cttgtgcgtt ttctgtaaca
    31681 gggtaatctt ctacttgtaa ttgaccatct tttaatgtgc caatatggtt atcatcgaag
    31741 taaagatctc cttgcttagc attgcttgtt accaaaaaag ttctaaaaga cacactcaaa
    31801 tctagcacgg gattatcacc atcatatgat ttgttgactt taatgtttcg cccgttgtgt
    31861 ttgcctctga tacttgcggt atattctgcc gttggtagcc gatcaagctt gactgagaac
    31921 tgttctgaat cagaaacagc aacttttttt tgatttaaaa gaacgtctgc ttgaggcaca
    31981 ttcgttttta tcgttaaatc catgggtttt atggcaatcc gataatcagg aaaaatccaa
    32041 aaacgacgac caacagactt tacttgaacg gcactatctt gactagcggc ttttaaatcc
    32101 tgcttttttt gcctcaattc tttctgacta taccttctaa acttagtata catcgcctcg
    32161 tcatttgtga tctgctcatt agtatcatcc cagactagat atgctttgat attctcaaaa
    32221 actggtcctg attgggccga tcgagcttta agataggcat taatacaatg atttttagag
    32281 tagtaaaagg caccaccgat caggaataaa aaaaggctag ttgcagctat tatagttatt
    32341 tgttttagtt tcttatgatg aaatggtttg gtcatcaaca gaccccaact ttctatgttt
    32401 ttctttacta ttatatcata aatggctaat ggattttcga agaaacctag atagttcact
    32461 gcctatacat ttttaggggc cgttaagcca aaattcaaga gagaattctc ataatattta
    32521 gatagctaac aatttcaaaa cacttcataa aagacttgaa tttttaaaaa gagcatttta
    32581 taatgtctgt gaaagcgtta tcgtttacta ggaggattcg catgataaac aaaaaaatat
    32641 cacttggagt tttaagtatt ctgacagcct tttcgcttca aagtgttagt tatgcttgta
    32701 ctggttttat tattggcaaa gatttaacca aagacggttc tcttctttat ggtcgaacag
    32761 aagatcttga gccacaccat aataaaaatt tcattgtacg tctagcaaag gacaatcctg
    32821 ctggcgaaaa atggaaagac ctctctaatg gttttgagta cccgttgcct gagcattctt
    32881 atcgctatag tgcgattcct gatgtaacac ctaacaaagg cgtttatgac gaagctggtt
    32941 ttaatgagtt tggcgtctct atgtctgcaa cagtatcagc ttcagctaat gatgccatcc
    33001 aaaaaattga tccttacgtc aaaaatggct tagcggaatc atctatgacc agtgtcattt
    33061 taccaagtgt caaaacagcc cgtgaaggtg tcgcattgat cgctaaaata gtcactgaaa
    33121 aaggagctgc tgaaggaaat attgttacct tggctgacaa agacggcatc tggtacatgg
    33181 aaattctctc tggtcaccaa tacgttgcca tcaaattccc agatgataaa tacgctgttt
    33241 ttccaaatac cttctatctc ggacatgtcg atttcaatga taaggaaaat acgattgcct
    33301 cagaagatgt ggaaaaagtc gctaaaaaag ccaaatctta taccgaagtt gatggtaaat
    33361 ttcatattgc caaatcttac aatccaccac taaacgatgc caaccgctct cgctctttct
    33421 cagggattaa atcacttgac cctgattcaa aagtaactta taaagacagc aattatgagt
    33481 tgctccaaag cactgataag accttcagtc tagaagatgc gatgaaactg caacgtaatc
    33541 gttttgaggg gctggatctt aaaccacttg atcagatggc attagacggt aagggtaaac
    33601 caaaatccaa aaaagctgtt aaaggttatg cttatcccat atcaaatcct aatgtcatgg
    33661 aagctcatat tttccaactg aaaaaagaca tccctgctga attgggtggt gtcatgtggc
    33721 tatctattgg cagtcctcgt aatgcccctt acttgccata ccttggcaat atcagtagaa
    33781 cctatgaagc ctatcaagaa aaaagcaccc aatataacga taagtcatgg tattggacgg
    33841 tgtcacacat taatgatctc gtggctgctc atccaaaacc atttggaact aaagtgattg
    33901 atgagatgaa aggcttggaa aaaacctgga tagccgaaca agacaaaagc accaaagaaa
    33961 tcagtgactt agtcgtcagt gaccccaaag ctgctcaaga aaaagctgat aagatttcac
    34021 tagatcgcgc tgaaaaaacc ttcaaacgct taaaagctat tgaagccaag ttggttaaag
    34081 aaaaacccaa aaacaagaaa ggcttgaata gatcataata ccataaccca aaaaagcttg
    34141 tatcaacaag tttctccata actagagctg aagtcaaaaa ataaggtctc acactttgtg
    34201 aaaccttatc ggtataggag gggtgaataa gatgggaatc gggttgagat agcattagtt
    34261 taagacgata cttctacaac caaatactta tcctattaag gaatgacatt agtatactag
    34321 ataagactta aagaaacctt aagccaaaaa aacaacaaga aacctctttc accccttttt
    34381 tcttatacta tactaaaagg tggtgaatct ggtgatagca acggttagag actggggcaa
    34441 tatgtgtgtc aaacataacg atatgatttt atgactccat agacaacacg ataacttccc
    34501 aggatgggtc cagccagaag gtaaagtcga gccctgcgaa tctttctttg aagcggcttt
    34561 atgagaacta aaagaagaga tagatctgac agctttaaac cttcaattaa agggtatttc
    34621 tagctttatc cagcctgaca aaaaaagagg gctatgtcta ttatgacttt ctatgtgaat
    34681 cctttgaagg agagctactg acagagtcgc gtgagggact cccaaaatag catgccatag
    34741 cagacttaga catgctggat atgccaaaag atatccgtga acatctcctt cttatcagtt
    34801 gatgctagtt gagcatgaag taactgcttc aagccatcac tatcttgaat tgtgttgtca
    34861 cgatgaaaat catggacagc atacataaac tcatcaatgg gcatgttact ttcatccaaa
    34921 atcagcataa atgtcgatat ggttaagtcc gtctcccctt tttcgaaacg cgacagctga
    34981 gaggttgata taccagcctt tgcgacatct tttaatcgta atccctttga ttctctaaag
    35041 gttttttaaa atctctccaa aatgattcat cacagacctc caacacccat atatgggaat
    35101 aacttttcat tgactccatg atagcacatg acaaagaaaa acaatgtatt ttccaataca
    35161 ttaaaagtct gtaaccacaa agattggcat tttatatcac aactaaaaaa acaaagatgg
    35221 gatatcatga gtcgaaatcc aatctttgtt cttttttcat agtaagaagc agacctttag
    35281 tctcaacttc tttttcataa tccttaatgc tatagagagc ttagaagccg cccatcattc
    35341 ctggatccat acctgctggc attgctggcg ctggcgtagc tggttcaggt ttattagcaa
    35401 caactgcttc tgttgtcaaa ataagactag ctacagaagc tgcattttga agcgctgatc
    35461 gtgttacttt gacagggtca atgattcctg ttttaatcat atcaacccac tcacctgttg
    35521 cagcattaaa tcctgttcct gcagggctgt ttttcaactt gtcaataact acggagcctt
    35581 cgtacccagc atttaaagca atttgacgta caggctcttc tagagcacga agcacaatgt
    35641 tacgtccagt agcatcatcg ccctcaagct caagagctgc tactttttca ataaccgtaa
    35701 taagtgctgt tccaccacca gcaacgatac cttcttcaac ggctgcacgt gtagcattta
    35761 gagcatcctc aatgcgaagt ttcatttctt ttaaagctgt ctctgttgga gctcctactt
    35821 tgataacagc tacaccacca gctaatttcg ccaaacgttc ttgtagtttt tcacggtcaa
    35881 agtcagaagt tgttgtttct aattgcgatt taatcagtgc aatacggtta gcaatagctt
    35941 ctgaacttcc tgaaccttca acaattactg tgctatcttt atcaactgta atcttagcag
    36001 cctgtccaag ggctgtcatt gtagcatctt ttaattcaag tcctagatcc tctgtaatca
    36061 ctgtaccacc tgtcaagata gcaatgtctt caagcatagc tttacgacga tcaccaaatc
    36121 ctggcgcttt gacagcaacc acattgaaag taccacgaat cttgttcaag acaagggttg
    36181 gaagtgcttc accatccaca tcatctgcaa taatgagtaa tggacggttg gttttaagaa
    36241 cttcctcaag tagtggcaaa atgtcttgga tgtttgacac ttttttatcc gtgattaaga
    36301 taaatgggtt ttcaaggtct gcaaccattt tttcattgtc tgtgaccatg tattgagaca
    36361 ggtaaccacg gtcaaattgc atgccttcaa ccacttcaag ttctgtttcc atacctcgag
    36421 attcttcgat ggtaatcaca ccatcgttgc ccacacgctc catagcttct gagatatact
    36481 ctccaacttt ttcagagcgt gatgatactg cagcgacctg agcaatagct tccttgccag
    36541 atacaggttg agcaatggct ttcaaggctt caacagctgt tgctgttgct gtttcaatgc
    36601 ctcgacggat accaattgga ttagcacctg ctgtcacatt ttttagtcct tcatgaacaa
    36661 tggcttgtgt caaaactgtt gcagtagtcg tcccatcacc agcaatatca ttggttttag
    36721 aagccacttc agacaccaat tttgctccca tgttttcaaa atgatcttct aattcgatct
    36781 ctttagcaat ggttaccccg tcattagtaa ttaagggaga accaaaagct ttttcaagaa
    36841 caacattgcg ccctttagga ccaagcgtta ctttgacggt atctgctaac atatcaactc
    36901 cgcgcaccat ggcagcacgc gcatctgctg aaaatttaat atcttttgcc atattcaatc
    36961 cttctttcta tttagagatt tgtcgtttta ttttgtaaca atagcaatga tgtcagattc
    37021 acggatgata gaaactttct catcatctac ggttacttct aaatcatgcc cattttcaac
    37081 taaaacctct tgacccactg aaactgaagg tagcacgcta tcacctgtaa tagtgcgaac
    37141 acccgtttca ctgacagcga ggactgtcgc ttttcgtgtt gactctttat gagtgcctgc
    37201 aaggacaaaa ccaccgactg tctgctcttt ttcatcatca aatcttacga ccacacggtc
    37261 acctaatggt tttaacatga aattttcctc caataaaaga atctttagta aagttagcac
    37321 tcatgttcat cgagtgctaa ctttatattc tattttatca cttggtcaaa aatagtcaag
    37381 aaaaaagaag ttatttttgt aagaataacc tctttttttg gtgacatcaa ggatgatcca
    37441 ccttttatat ggaaattaag ctatgtgaaa cgttaatttg ccatgtgata atccaatttt
    37501 tagcgtatgc ccacttgtca attctcgaga aagaataagc tctgatagct tatcttctat
    37561 ctcagtttgc agcgttcgac gtaatggtct tgcccccata tgctcatcat agccgacctc
    37621 ggacaaatgt ttcaaggcca aaggctgaat tttaagggta ataccttttt ctgccaatgt
    37681 agtaatcagg ggctgtacca tgattttaac cacatcgcgc atgttatctt gggtcagact
    37741 atgaaagacc actttttcat caatacgatt gataaattct gggcggtaag tttttcttaa
    37801 ttcttctaaa atacgtttct ccatagcttg atggtcttgg tgaatgtctt tgaccccaaa
    37861 accgaccgtt ttatcatcgc gcagggctgt tgcgccaaga ttgctggtca tgataataat
    37921 agtatttgaa aaatcgacct tacgcccacg actatcagtc aatataccat catctaatac
    37981 ttgaaggaga acgttaaaaa tatcaggatg tgctttttcc acttcatcaa aaagcaagac
    38041 tgaataaggt ttatttctaa ctttctgtgt cagttcacct ccttcatcat agccgacata
    38101 accaggaggt gctccattaa gcctagacgc tgcgaatttt tccatgtact cagacatatc
    38161 aaaacgaata agcgctgctt catcatcaaa gagaacttct gcaagggcct ttgctagttc
    38221 tgtcttacct actcctgttg ggccaagaaa cataaatgat ccaataggac gttttcctgt
    38281 tcgaatacct gactgattac gacgaatggc tcttgaaata gccgtaacag cagcatcctg
    38341 accaatcaca cgcttatgca gttctttttc taaattgagg tattttttac tatcagcttg
    38401 cgtcagtttt tcaagtggaa ttcccgataa cttactcaag gttgccaaaa tatcatcttc
    38461 tgtcaccggt gttggttttc tcatctgacc ttttgcttct ttagctaaga ggcgagatac
    38521 ttttttcata tcaccattga taagagcttg gtctattggt gttaaagtct caggtgctga
    38581 ttttttcacc atgttttgca cagcagcact agcttcatct agtaaatcga tagctgaatc
    38641 agggagattt ttactggtta aataacggtg tgccattttt acagctgttt taactgcctc
    38701 atttgatatc gagacattat ggtaggtctc ataagataat tttaggccca tcaaaatctg
    38761 ataagcatct tctgtattag gttcttcaat taatatttta gcaaaacgac gcgaaagagc
    38821 tgcatctttt tcaatatgtt tttggtattc ttcttgagtt gttgctccaa ccatatgaag
    38881 agtgccgcgc gataatgctg gttttaaaat gttagccgca tcaagtgtac tgtcaatacc
    38941 actgccagaa cccataatag tatgtagttc atcaacaaaa agaataatct gaccatcagc
    39001 ttcaatatca tcaatgattt gattcatgcg ctcttcaaaa tccccacgaa aacgggttcc
    39061 tgctaccaca ctcatcatgt ctaattctag gacacgcatc tccttaagtt cataaggaat
    39121 agcgccattt gcaatccgtt gagcaaggcc ataagcaagc gcagttttac caacacctgc
    39181 atcacctacc aagacaggat tgtttttcgt tttacgactt agtacctgaa tcatacgaga
    39241 tacttcttgg tcacgtccaa tcaccgattc taacaaacct tgtcttgcca tttcagtcaa
    39301 atctcttgtg aaatcactca actcaccagc tgtacttggt ggcttcatca tatctgaaaa
    39361 ggtcccttgt gttttcgttt ttttaggctt acgtagttcg tgaatagcct tgatcatttc
    39421 cttactgtaa cctgcatgac gttctattgc ttttcgcaag tcagctaatc gcggctgccc
    39481 attgccgtta tcttttatct gatagccagc tatttctaac aaacgactcg ccataatatc
    39541 tggattcaat aaaatagcaa ataagacatg ctcagagccg acttcttgat ccctagtgat
    39601 ttggctaata gcctgcgcaa aagctaacaa gttagtcaaa gttttagatt gaggtctgaa
    39661 gtctacacga gacaactgtt ctttaggggt tttgcccatg gctaaaatag ctgcagcttc
    39721 atattcttct atggcgactt gggcatcata ttcacttaaa atcatatttg ctaaagaatt
    39781 atctacagct accatagcta acaaaacatg ccaagtttcc aggcaatggc tatcaaagcg
    39841 agcagcttgg aactgcgcct gtctaaaaat gtcttgcatc ttcgttgaat acataatcat
    39901 taattgcttc cctttctgtc aattcgttgc aataagcgat agagcattcg tgcacgaata
    39961 gttgaaccat cagttcctaa aacatcatca gacgccacag ccaaaatgat atttccctca
    40021 cgctctgtca ataagtgttc gtcaaaaagc aattgtatcg agtccgtgaa aacttgctca
    40081 ctgatacagt cttcaatagt tgccattaaa ttgccaatca gatggtgttt gtctgaaaaa
    40141 tgaaccttgg caatacgaat atagcctcca ccacctcgtt tactctctac ttcatagcct
    40201 cgactctccg taaaacgggt tttaatgaca tagttgatct gacttgggac aacttgaaac
    40261 gaatctgcta gcatggaccg cttaatttct gctattcctg acttagctaa taattcttta
    40321 atatactctt caatgctgtc tgaagtattt ttggttggca tgctgtcact cctttgcttg
    40381 cgggctactc taaaaactta gtagcaccac gtcaatacat tttgactaaa actgactatt
    40441 attataacaa atacaagacc ttaaacgcaa ctcttaatca ttaaaggtaa ctggtagaaa
    40501 tcaaaaaagc agttgctgtt tccaacatct gcttctcttt agttacttta accagattag
    40561 gccaatttag tgatattgac tgcttgaggt ccacgttgac cttcttcgac gtcaaatgcc
    40621 actttttgtc cttcttctaa cgttttaaaa ccattagttt ggatggctga aaaatgtgca
    40681 aagacatctt gaccgttttc agttgaaata aaaccaaaac ctttttcagc attaaaccat
    40741 tttactgtac cttgtgccat atacatccac ttcctttcta aaaatcattt gtaaaaatag
    40801 agagaaataa agatgttgaa acacaaatac taactcaaaa actaatttac tcactaagag
    40861 taacacattt tataacactt gtcaataaca tgcttaaaaa cattaagaat atagttgcat
    40921 tgtaatgggt ggttacttta taaagctgac tatggtaagg taaacaagta gagattcaac
    40981 tctactcgct ctcacatcac cgtgtctatc gttaaggtgc acggcagttc aactaacttt
    41041 taacgcatat cgtttaaggg ggtaagaact ctgaccttta tttgcaatcg tttaccaatt
    41101 ttggccatag tatttttcat acctaataat caggctctaa aagacatctt cgggaaattt
    41161 gaccgacttt tgaccgactt tatttctttt tttctctttt tttatcctgc cgcaaaaaat
    41221 aaaaaccttg atttaacaac gttttcacga agttaatcaa ggcttgtttt gtatataaaa
    41281 ggcggtagac ggatttgaac cgacgatcaa gcttttgcag agccgtgcct taccacttgg
    41341 ctataccgcc acaacaaaga ttattttacc ctaattccac aaatccgtca agcactattt
    41401 gcacaagaca tatccaatta atataacagc cattccctga tctcatgcca aaataggtta
    41461 caatattagc gattaggtaa ccataatatt aagttgcctt aacggaatca aaaaagtttt
    41521 ttgtaaacg
//
LOCUS       DAUGJR010000012        41089 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUGJR010000012 DAUGJR010000000
VERSION     DAUGJR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41089
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.012"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            18..98
                     /locus_tag="VH800_000639"
     tRNA            18..98
                     /locus_tag="VH800_000639"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VH800_000640"
     tRNA            105..175
                     /locus_tag="VH800_000640"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VH800_000641"
     tRNA            187..259
                     /locus_tag="VH800_000641"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VH800_000642"
     tRNA            268..339
                     /locus_tag="VH800_000642"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VH800_000643"
     tRNA            359..442
                     /locus_tag="VH800_000643"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            702..887
                     /locus_tag="VH800_000644"
     CDS             702..887
                     /locus_tag="VH800_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361725.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWLEP"
     gene            1300..2139
                     /locus_tag="VH800_000645"
                     /pseudo
     CDS             1300..2139
                     /locus_tag="VH800_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
     gene            2208..2651
                     /locus_tag="VH800_000646"
     CDS             2208..2651
                     /locus_tag="VH800_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEQ8361726.1"
                     /translation="MGILEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2655..3374
                     /locus_tag="VH800_000647"
     CDS             2655..3374
                     /locus_tag="VH800_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361727.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEAETDDEKGGHGHA"
     gene            3367..4182
                     /locus_tag="VH800_000648"
     CDS             3367..4182
                     /locus_tag="VH800_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8361728.1"
                     /translation="MLDILFYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4222..4605)
                     /locus_tag="VH800_000649"
     CDS             complement(4222..4605)
                     /locus_tag="VH800_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8361729.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEGHYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWEGITINQENWDLTPFLKHL"
     gene            complement(4656..5912)
                     /locus_tag="VH800_000650"
     CDS             complement(4656..5912)
                     /locus_tag="VH800_000650"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEQ8361730.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSIDNHNIVEILVAAKISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6004..8316
                     /locus_tag="VH800_000651"
     CDS             6004..8316
                     /locus_tag="VH800_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8361731.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGIVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLFNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8580..12146
                     /gene="rpoB"
                     /locus_tag="VH800_000652"
     CDS             8580..12146
                     /gene="rpoB"
                     /locus_tag="VH800_000652"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8361732.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGTVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQQ
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12237..15878
                     /gene="rpoC"
                     /locus_tag="VH800_000653"
     CDS             12237..15878
                     /gene="rpoC"
                     /locus_tag="VH800_000653"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEQ8361733.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDRLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVIPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16030..16395
                     /locus_tag="VH800_000654"
     CDS             16030..16395
                     /locus_tag="VH800_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEQ8361734.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16488..17426
                     /gene="tadA"
                     /locus_tag="VH800_000655"
     CDS             16488..17426
                     /gene="tadA"
                     /locus_tag="VH800_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEQ8361735.1"
                     /translation="MVQALAKAILAKAEQVHAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17410..18396
                     /locus_tag="VH800_000656"
     CDS             17410..18396
                     /locus_tag="VH800_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEQ8361736.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18398..18724
                     /locus_tag="VH800_000657"
     CDS             18398..18724
                     /locus_tag="VH800_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEQ8361737.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18699..19127
                     /locus_tag="VH800_000658"
     CDS             18699..19127
                     /locus_tag="VH800_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEQ8361738.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19132..19368
                     /locus_tag="VH800_000659"
     CDS             19132..19368
                     /locus_tag="VH800_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8361739.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEMTLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19361..19795
                     /locus_tag="VH800_000660"
     CDS             19361..19795
                     /locus_tag="VH800_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEQ8361740.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19779..20105
                     /locus_tag="VH800_000661"
     CDS             19779..20105
                     /locus_tag="VH800_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8361741.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20203..21156
                     /locus_tag="VH800_000662"
     CDS             20203..21156
                     /locus_tag="VH800_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8361742.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21215..22411
                     /locus_tag="VH800_000663"
     CDS             21215..22411
                     /locus_tag="VH800_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEQ8361743.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22598..22906
                     /locus_tag="VH800_000664"
     CDS             22598..22906
                     /locus_tag="VH800_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361744.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLPLIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(22989..23759)
                     /locus_tag="VH800_000665"
     CDS             complement(22989..23759)
                     /locus_tag="VH800_000665"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEQ8361745.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLA
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL"
     gene            complement(23807..24874)
                     /gene="pepA"
                     /locus_tag="VH800_000666"
     CDS             complement(23807..24874)
                     /gene="pepA"
                     /locus_tag="VH800_000666"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEQ8361746.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
                     IIPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEEAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKCY"
     gene            25330..25623
                     /locus_tag="VH800_000667"
     CDS             25330..25623
                     /locus_tag="VH800_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEQ8361747.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25620..25937
                     /locus_tag="VH800_000668"
     CDS             25620..25937
                     /locus_tag="VH800_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEQ8361748.1"
                     /translation="MIRPTSYESLATLIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25955..26581
                     /locus_tag="VH800_000669"
     CDS             25955..26581
                     /locus_tag="VH800_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEQ8361749.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDENLARLNAELAKEGFSERLEPIVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIEFDESAVVGEAFDPAKHWKG"
     gene            26733..27128
                     /locus_tag="VH800_000670"
     CDS             26733..27128
                     /locus_tag="VH800_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8361750.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27388..28029)
                     /locus_tag="VH800_000671"
     CDS             complement(27388..28029)
                     /locus_tag="VH800_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEQ8361751.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIERRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYEVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28049..29026)
                     /gene="dusB"
                     /locus_tag="VH800_000672"
     CDS             complement(28049..29026)
                     /gene="dusB"
                     /locus_tag="VH800_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEQ8361752.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(29013..29885)
                     /gene="hslO"
                     /locus_tag="VH800_000673"
     CDS             complement(29013..29885)
                     /gene="hslO"
                     /locus_tag="VH800_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEQ8361753.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIISDKA"
     gene            complement(30032..31525)
                     /gene="rofA"
                     /locus_tag="VH800_000674"
     CDS             complement(30032..31525)
                     /gene="rofA"
                     /locus_tag="VH800_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEQ8361754.1"
                     /translation="MIEKYLESSIESKCQLIVLFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSHDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQYCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRDLNHKHFHLFCHYVEQSLRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
     gene            31788..34061
                     /gene="cpa"
                     /locus_tag="VH800_000675"
     CDS             31788..34061
                     /gene="cpa"
                     /locus_tag="VH800_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus tip adhesin"
                     /protein_id="HEQ8361755.1"
                     /translation="MKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSM
                     VGAKTVFGLVESSTPNAINPDSSSEYRWYGYESYVRGHPYYKQFRVAHDLRVNLEGSR
                     SYQVYCFNLKKAFPLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKLRAVMY
                     NGHPQNANGIMEGLEPLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLS
                     LMRQALKQLIDPNLATKMPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPP
                     TPGDPPMPPNQPQTTSVLIRKYAIGDYSKLLEGATLQLTGDNVNSFQARVFSSNDIGE
                     RIELSDGTYTLTELNSPAGYSIAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVE
                     AYNDFEEFSVLTTQNYAKFYYAKNKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTT
                     GEVKYTHIAGRDLFKYTVKPRDTDPDTFLKHIKKVIEKGYREKGQAIEYSGLTETQLR
                     AATQLAIYYFTDSAELDKDKLKDYHGFGDMNDSTLAVAKILVEYAQDSNPPQLTDLDF
                     FIPNNNKYQSLIGTQWHPEDLVDIIRMEDKKEVIPVTHNLTLRKTVTGLAGDRTKDFH
                     FEIELKNNKQELLSQTVKTDKTNLEFKDGKATINLKHGESLTLQGLPEGYSYLVKETD
                     SEGYKVKVNSQEVANATVSKTGITSDETLAFENNKEPVVPTGVDQKINGYLALIVIAG
                     ISLGIWGIHTIRIRKHD"
     gene            34054..34611
                     /gene="sipA"
                     /locus_tag="VH800_000676"
     CDS             34054..34611
                     /gene="sipA"
                     /locus_tag="VH800_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase-like pilus assembly factor
                     SipA"
                     /protein_id="HEQ8361756.1"
                     /translation="MTRADFRTSNSSGELNKLSFSDKEAIKPLLIGLVKKIALILIGG
                     YLLFHFVFGFMIIKRNDMAPSVKAGDAILFYRLSQTYKVEEAVVYEDSKTSITKVGRI
                     IAQAGDEVDLTEQGELKINGHIQNEGLTFIKSREANYPYRIADNSYLILNDYYSQESE
                     NYLQDAIAKDAIKGTINTLIRLRNH"
     gene            34644..35666
                     /gene="fctA"
                     /locus_tag="VH800_000677"
     CDS             34644..35666
                     /gene="fctA"
                     /locus_tag="VH800_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus major pilin FctA"
                     /protein_id="HEQ8361757.1"
                     /translation="MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSN
                     ALIPNTDFTFKIEPDTTVNEDGNKFKGVALNTPMTKVTYTNSDKGGSNTKTAEFDFSE
                     VTFEKPGVYYYKVTEEKIDKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGS
                     KVPIQFKNSLDSTTLTVKKKVSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKG
                     GQAPVQTEASIDQLYHFTLKDGESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQD
                     GAVKNIAGNSTEQETSTDKDMTITFTNKKDFEVPTGVAMTVAPYIALGIVAVGGALYF
                     VKKKNA"
     gene            35676..36389
                     /gene="srtC1"
                     /locus_tag="VH800_000678"
     CDS             35676..36389
                     /gene="srtC1"
                     /locus_tag="VH800_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus polymerization class B sortase
                     SrtC1"
                     /protein_id="HEQ8361758.1"
                     /translation="MIVRLIKLLDKLINVIVLCFFFLCLLIAALGIYDALTVYQGANA
                     TNYQQYKKKGVQFDDLLAINSDVMAWLTVKGTHIDYPIVQGENNLEYINKSVEGEYSL
                     SGSVFLDYRNKVTFEDKYSLIYAHHMAGNVMFGELPNFRKKSFFNKHKEFSIETKTKQ
                     KLKINIFACIQTDAFDSLLFNPIDVDISSKNEFLNHIKQKSVQYREILTTNESRFVAL
                     STCEDMTTDGRIIVIGQIE"
     gene            36411..37058
                     /gene="fctB"
                     /locus_tag="VH800_000679"
     CDS             36411..37058
                     /gene="fctB"
                     /locus_tag="VH800_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus minor pilin FctB"
                     /protein_id="HEQ8361759.1"
                     /translation="MKKSILRILAIGYLLMSFCLLDSVEAENLTASINIEVINQVDVA
                     TNKQSSDIDETFMFVIEALDKESPLPNSVTTSVKGNGKTSFEQLTFSEVGQYHYKIHQ
                     LLGKNSQYHYDETVYEVVIYVLYNEQSGALETNLVSNKLGETEKSELIFKQEYSEKTP
                     EPHQPDTTEKEKPQKKRNGILPSTGEMVSYVSALGIVLVATITLYSIYKKLKTSK"
     gene            complement(37245..38567)
                     /locus_tag="VH800_000680"
     CDS             complement(37245..38567)
                     /locus_tag="VH800_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003627959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEQ8361760.1"
                     /translation="MTCPVETEDITYRRKKIKGRRQAILAQFEPELVHHELIGDSCTC
                     PDCHGTLTEIGSVVQRQELVFIPAQLKRINHVQHAYKCQTCSDNSLSDKIIKAPVPKA
                     PLAHSLGSASIIAHTVHQKFTLKVPNYRQEEDWNKLGLSISRKEIANWHIKSSQYYFE
                     PLYDLLRDILLSQEVIHADETSYRVLESDTQLTYYWTFLSGKHEKKGITLYHHDKRRS
                     GLVTQEVLGDYSGYVHCDMHGAYRQLEHAKLVGCWAHVRRKFFEATPKQADKTSLGRK
                     GLVYCDKLFALEAEWCELPPQERLVKRKEILTPLMTTFFDWCREQVVLSGSKLGLAIA
                     YSLKHERTFRTVLEDGHIVLSNNMAERAIKSLVMGRKNWLFSQSFEGAKAAAIIMSLL
                     ETAKRHGLNSEKYISYLLDRLPNEETLAKREVLEAYLPWAKKVQTNCQ"
     gene            complement(38530..38757)
                     /locus_tag="VH800_000681"
     CDS             complement(38530..38757)
                     /locus_tag="VH800_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8361761.1"
                     /translation="MSSQDKVIKTQAKTIETMANELALLREQVAYLTQKLYGKSSEKA
                     MPMTGQLSLFDQDQLPEEADDLPSRNRRHYL"
     gene            complement(38808..39158)
                     /gene="tnpB"
                     /locus_tag="VH800_000682"
     CDS             complement(38808..39158)
                     /gene="tnpB"
                     /locus_tag="VH800_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEQ8361762.1"
                     /translation="MTIRLNDLGQVYLVCGKTDMRQGIDSLAYLVKSQHELDLFSGAV
                     YLFCGGRRDRFKALYWDGQGFWLLYKRFENGKLAWPRNRDEVKCLTAVQVDWLMKGFF
                     ISPNIKISKSHDFY"
     gene            39388..40217
                     /locus_tag="VH800_000683"
                     /pseudo
     CDS             39388..40217
                     /locus_tag="VH800_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936782.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
     gene            complement(40411..41076)
                     /locus_tag="VH800_000684"
     CDS             complement(40411..41076)
                     /locus_tag="VH800_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361763.1"
                     /translation="MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKKLVDSDKNIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPTEITYEHHY
                     WDGTVRSETRNNTQWHYDWKSQQTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEDNYKNKWDKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
BASE COUNT        12654 a         7275 c         8657 g        12503 t
ORIGIN      
        1 aaagtttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tgtaaacctt gttttttgtt
      481 ttgatcttaa gctgtagcta cgtagtacaa tctcttatat tactgataag gtctatttaa
      541 tgcgcaagat ttgtggtatg atgaatatga ttgagtattg atgctttatg ggattaccgg
      601 taaggttttg aaaaaggttt gtcactacta ggtgcttttt taactataga aagacagtta
      661 tggattgatg tattgtaact aatgttggag gttaatggtg gttgagtttt gagatattta
      721 cactgataat cgggtggaaa ctggtcgggt atcgggtaat ggagtgtggt tcttcgttta
      781 agcaaggaga ttatcgtttg gtggttcata tttgcttgtt aaatgttagg gatgagatgc
      841 tgagtcagca aggccatgaa gataaagctg actggctaga gccttgagat gtgacgtttg
      901 gtggaagtcc tttttggtga gatggcacag catatagtaa tattagatcc tgaggaagaa
      961 ttgggacttt cattaggctt gactggggta tgacctcact ttacaattca tttcgatgat
     1021 gggtttgatg atacgttttt agttcaagac tttgtagagt tggagaattt ggttctttat
     1081 gaagaagaag tgcaggtaat tcgttgagcc agtcgtgaag atattttagg tatgattgat
     1141 gaaggttcgt ttattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggc
     1201 caatataaag tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt
     1261 atatttgata gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga
     1321 gcttctgtaa aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac
     1381 gatttatcga tggtcatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata
     1441 gatgacaata agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat
     1501 gatgtttata agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc
     1561 gtttacttgg aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct
     1621 gttactatca gagcattaaa tcagatggct ccttactctt agccgaaaag atatgatgga
     1681 tattggtata ccgattggta gtgatgtgcc ttattgcttg ctttcaggtt gtgcccaagt
     1741 cactggtaaa ggtgaagtgg tttgtcgcat tttggggctg ttatcgtctt gggtggtttt
     1801 ggttaaacca gattttggta tctcgacttg aacatttttt ctagatatta attgtaaaat
     1861 catttcaaga gtgtctacta ctcatttggt tgcggcgatt gaagcgggta actataatga
     1921 tgggatattg actgaaatga acaatttgct ggaagatatt ttcattgcca agcgaccctt
     1981 tattcaaaaa ataaaagaga aaacactgca agctggtgct gctaatgctt tgatgacagg
     2041 aagtggaccg actgtttttg ctttgtgcca aaccgaaaaa caaactataa tagtttaaaa
     2101 ggactttgca aggaagtttt taaggtgaga atgttgtaat attttgttgg gattgcttct
     2161 ttggaagctt catgttataa ttaactggtt aatgaaagag gagatttatg gggattttag
     2221 aaaaaaaact tgataactta gtaaatacta ttttattaaa agcagaaaat cagcatgagt
     2281 tattatttgg agcttgtcaa agtgacgtta agcttactaa tacgcaagaa catattttaa
     2341 tgttactatc tcagcaacgt ctcactaata cagatttggc taaggcatta aatattagtc
     2401 aggcggcagt aactaaggct atcaagagtt tggtcaaaca agacatgtta gcaggaacta
     2461 aggatacggt tgatgctagg gtgacttatt ttgaattaac cgagttagct aagcctattg
     2521 cgtcagaaca tacccatcat catgatgaaa ccttaaatgt ttacaaccgt ttattacaaa
     2581 aattctccgc gaaagaatta gagattgtag ataagtttgt aacagttttt gctgaggaat
     2641 tagaagggta atccatgaga tacatatcag tgaaaaatct ctcctttcaa tatgaaagtg
     2701 agccagtttt agaagggatc acttatcatt tagatagtgg agaatttgtc accatgaccg
     2761 gtgaaaatgg tgctgcaaag tcaaccttaa taaaagcaac cttaggaatt ttacaaccaa
     2821 aggctggacg agttactatt gctaaaaaaa ataaagacgg taaacaatta agaattgctt
     2881 acttgccgca gcaagtagct agctttaacg ctggttttcc atccaccgtt tacgagtttg
     2941 tcaaatcagg tcgctaccca cgtagtggtt ggtttagaca tttgaacaaa cacgatgaag
     3001 agcatgtgca agcaagctta gaagcagtcg gcatgtggga aaaccgtcat aagagaattg
     3061 gtagtttatc aggtggtcaa aaacaacgtg tggttattgc ccgtatgttt gcttctgacc
     3121 ctgatatttt tgtgctagac gagccaacaa cgggaatgga tagcggtact actgatacct
     3181 tttatgaact gatgcaccac agtgcacatc aacatgggaa atccgttctg atgattaccc
     3241 atgacccaga agaagtgaag gcttatgctg atcggaacat tcatttagtc agaaaccaaa
     3301 aacttccttg gcgttgtttc aacattcatg aagctgaaac agatgacgaa aaaggaggtc
     3361 atggtcatgc ttgatatttt attctatgat ttcatgcaac gggcggtaat ggcggtagtt
     3421 gccattagta tttttgctcc gattttaggt attttcctta ttttacgtcg tcaaagtttg
     3481 atgagcgata cccttagtca tgtttctttg gctggggtag cgcttggggt agtccttggt
     3541 atttcaccaa ccatcactac tattattgtt gtggttttag ctgctatttt gttagaatac
     3601 ctgcgtgtag tttacaaaca ctacatggag atttcaacgg cgattttgat gtcacttggc
     3661 ttggccctat ctctgattat tatgagtaag tcgcatagtt catcaagcat gagtttagaa
     3721 caataccttt ttggatcgat catcacgatt agtatggaac aagttgtcgc cttgtttgct
     3781 attgctgcga ttattttaat cttgaccgtt ctcttcatta gaccgatgta cattctgacc
     3841 tttgatgaag atactgcttt tgtagatggt ttgcccgttc gcttgatgtc tgttctattc
     3901 aatatcgtca ctggggttgc tattgctttg accattccag cagcaggagc acttttggtt
     3961 tctaccatta tggtcttgcc agcaagtatc gcaatgagat tgggtaaaaa ctttaaaaca
     4021 gttatcttac tgggaattgt catcggtttt agcggtatgt tatctggtat tttcttatct
     4081 tatttctttg aaacgccagc tagtgccact attaccatga ttttcattag tattttcctc
     4141 ttagttagtc taggtggaat gcttaaaaaa cggttatttt aataagaaaa atcctcacat
     4201 gtttaacatg tgaggattta tttataaatg ctttaaaaag ggggtaaggt cccaattttc
     4261 ttgattaatg gtgatgccct cccaaaagct atcattagtt aaacgaggaa tcaaatgaag
     4321 gtgaaaatga gtcccctcat ccatcaactc cttgtcattg ctgacgctag taacgcctga
     4381 aatgggaagg tgctgctcta gcttagcaac tagagcggct tgtaagtcga tgagatcata
     4441 gtgcccttcc tttggtagtt gtgtcagact agtgtaatgg tctttggaaa tcagtaaaag
     4501 gtgccccttt tggataggat cgatatcaaa aacaaccttg aaatattgac tttgagtcag
     4561 tagctgattt gctttgagct gatggcaaaa gatacattct gtcataggta catctcctta
     4621 tgaaaaaacg agccagagct cgtttaatcg gttatctagt aagtgagaac agcgtatttt
     4681 ttcttaccgc ggcgaataac ggttaattga tcatcaattt tatcatcatt acttaattgg
     4741 taatctaaat cttgaacgcg gtctccgtta atgtagattg ctccattttg cacgtcttca
     4801 cgcgcctggc gttttgatgg ggaaatctta gcagctacta aaatctcgac aatattatga
     4861 ttgtctattg attgaacgtg ataatttggt acattgctca atccttgttt taattcattg
     4921 gcagaaagat ttttgatgtt tccagcaaat aactgctcgg taatgttaag agcttgttta
     4981 taagcttctt cgccatgaac caaggtaacc acttcgcgtg ccaaggtttt ttgagcgaga
     5041 cgctcgtgac gagcggcatt aaattgagtt tcaatttctg caatctcatc tagagataag
     5101 aaggtgaaga ttttcaagaa acgcactgca tcatcatcca tgacatttaa ccagaattgg
     5161 tacatctcgt aaggagacgt cttatcggca tcaagccaga cagcattacc ttctgattta
     5221 ccgaattttt tcccggttga gtcagtgatg agtggtacag tcatgacgtg cccagtttta
     5281 tcagcctttt tgcggagcaa ttcagtacca gctgtcatat taccccactg gtcagagccg
     5341 ccaatttgta aggttacatt atgcttgtca ttgagttcgt agaagtcgta gccctgcatg
     5401 atttggtaag caaactcagt gtaagaaatg cctgtttcaa tgcgtttttt aacagagtct
     5461 ttactcatca tgtagttaac ggtgaagtat ttaccgacat cacggaggaa gtcaataaag
     5521 ctgatttgcg agaaccagtc gtagttgttg acaagctctg ctttattatc accattttca
     5581 aaatcaagga aagtagacaa ctgcccttta atcttgtcac tccactccaa aactgtttct
     5641 ttggtttgaa ggctgcgctc tgcatcttta aaggaaggat caccaattaa acctgtggca
     5701 ccccccacaa gagcgtaagg tttgtgccct gctagttgca agcgacgaga tgttaagata
     5761 gccactagat ggcccagatg aaggctgtca gcggttggat cataaccggt ataataggat
     5821 acttgccctt ctgttaatgc tttgacaagg gcttgttcat cagtcgtttg aaagaccaag
     5881 ccacgagctt tgagttcttc aaaaatattc ataggctttc tccattttca ttatagtttc
     5941 gaatcattat atcaaaaaac gctactgcta tgcaagcttt atcaaagttt ggtataatga
     6001 taaatgaggt attttatggt gaaatggaac acgaaacaaa agcgtataag tcatcaaaga
     6061 ttaggtctct tggatttggg gccggtgcta ttacgtacgt tgagactact gtctaacttt
     6121 ttttatattg ttatcttcct ttttggaatg atgggatttg gtatggcatt tgggtatttg
     6181 gctagtcaga ttgaatctgt taaggtacca agtaaagaaa gtttagtcaa acaagttgaa
     6241 tcattaacga tgatttcgca aatgaactat tctgataata gtttaatttc tactttagat
     6301 acggatttac ttcgaacacc agtagctaat gatgcgattt cagagaatat caaaaaagct
     6361 attgtatcaa cagaagacga acattttcaa gaacataaag gtatcgtgcc aaaagctgtt
     6421 tttcgggcaa cattggcttc tgtattggga tttggagaag ctagtggagg ttcgacctta
     6481 acacagcaat tagtcaagca acaagttttg ggagacgatc ccacatttaa gcgcaagtct
     6541 aaggagatcg tttacgctct tgccttagag cgttatatgt ccaaagacaa tatcttatgt
     6601 gattatctta atgtttcacc ttttggccgt aacaacaagg gtcaaaatat tgctggtgtt
     6661 gaagaagctg cgcgtggcat ttttggcgtt tctgccaaag atttaacggt gccacaggca
     6721 gcatttttgg cgggtcttcc gcagagtcct attgtttact ctccttattt gtcaacggga
     6781 caactgaaat cagaaaagga catggcttat ggcatcaagc gtcagcaaaa tgttctcttt
     6841 aacatgtacc gtacaggtgt tctgtctaaa aaagaatacg aggactataa ggcttatccg
     6901 attcaaaagg attttattca accgggaagt gcaatagtaa ataatcacga ttacctttat
     6961 tacacggtgt tagcggatgc taagaaagcc atgtatagct atttgattaa gcgagataag
     7021 gtgtctagtc gtgacttgaa aaatgacgag actaaggctg cttatgaaga gagagcctta
     7081 acagaattgc aacagggtgg ctataccatc accacaacca ttaataagcc tatttacaat
     7141 gcgatgcaga cagcggcagc tcagtttggt ggcttgttag atgatggcac tggtacagtt
     7201 caaatgggaa atgtcttgac agacaatgcg actggtgctg tgttaggttt tgttggtggt
     7261 agagattatg ctctgaatca aaataatcat gctttcaata cagttagatc gccaggttct
     7321 agcattaaac cgataatcgc ttatggtcct gctattgatc aaggtttaat ggggagtgct
     7381 agcgttttgt ctaattaccc aacaacttac tcgagtggcc aaaaaatcat gcatgctgat
     7441 agtgaaggaa cagccatgat gccacttcaa gaggccctaa atacttcttg gaacatccca
     7501 gctttttgga cacagaaatt actgcgtgaa aaaggtgtcg atgtcgaaaa ttatatgaca
     7561 aaaatgggtt ataagattgc agactactcg attgaaagtt tacctctagg gggcggtatt
     7621 gaagtctcgg ttgctcaaca aaccaatgct taccaaatgc tttcaaacaa tggcttatat
     7681 caaaagcaat atattgtaga taagattact gctagcgatg gtacagtcgt ttacaaacat
     7741 gaaaataagc caattcgtat tttttctgca gcaacagcta cgattttaca agaattgttg
     7801 agaggtccga ttacttcagg cgctacgact actttcaaga accgtttggc ggctattaat
     7861 ccgtggcttg ctaatgctga ttggattggt aagaccggaa caactgagaa ttatacggat
     7921 gtttggctag tcctgtctac tccaaaagtt actttaggcg gttgggcagg acatgatgac
     7981 aatacctcat tagcgccatt aacaggatat aacaataatt ctaattatct tgcctattta
     8041 gctaatgcca ttaatcaggc cgatcccaat gttattggag tagggcaacg cttcaactta
     8101 gatccaggag tcattaaggc gaatgtcttg aagtcaacag gtttacaacc aggaactgtt
     8161 aatgtcaatg gacatacttt ttctgttggt ggagaaatga ccaccagtct atggtcccaa
     8221 aaaggaccgg gggctatgac ttaccgattt gctattggtg gcacggatgc cgattatcaa
     8281 aaagcctggg ggaacttcgg gttcagaaaa aattaggttg ccatttatcg ataaaaaggg
     8341 tataatagta ataactattt gtcgtccaat ctagctgaaa tattgtccag ttaggaagaa
     8401 cagcagttaa atcacactga taaagtcaga tttagctgct ctttttgtgt ctatttttag
     8461 aaaagatagg gtttgtaacc tatatttaaa tattctaaaa attaacattt agggcaaatg
     8521 ataacttagt tgcgatttgc tgaaacagca aagcttaaat agaagaagga gctaaaaact
     8581 tggcaggaca tgaagttcga tacggaaaac accgtacacg tcgtagcttt tcaagaatca
     8641 aagaagttct tgatttacca aatttgattg aaattcaaac tgactcattc caagatttcc
     8701 tcgattcagg tttgaaagaa gtatttgaag atgtacttcc tatttcaaac tttacggata
     8761 ctatggaact tgaatttgtt ggttacgaat ttaaagaacc taaatatacc cttgaagaag
     8821 ctcgtatcca cgatgcaagt tattctgcac caatctttgt taccttccgt ttggtcaata
     8881 aagaaactgg tgagattaaa actcaagaag tcttctttgg tgatttccca atcatgacgg
     8941 aaatgggtac ctttattatc aatggtggtg aacgtatcat cgtttctcag ttggtgcgtt
     9001 ctccaggtgt ttatttcaac gataaagttg ataaaaacgg taaagttggt tacggatcaa
     9061 cagtgattcc taaccgtggg gcttggttgg aattagagac tgactcaaaa gacattgcct
     9121 acactcgtat tgaccgtacc cgtaagattc cattcacaac cttggttcgt gcccttggtt
     9181 tctcaggtga tgatgaaatt gttgatatct ttggtgaaag cgaccttgtt cgtaatacca
     9241 ttgaaaaaga cattcacaaa aatccaagtg attctcgtac agacgaagcc cttaaagaaa
     9301 tttacgagcg tcttcgtcca ggtgagccaa aaactgcaga tagctctcgt agtcttttga
     9361 ttgcgcgttt ctttgatgca cgtcgttacg atttggctgc ggttggtcgt tacaaagtga
     9421 acaaaaaact taatatcaag actcgtcttt tgaaccaaat cattgctgaa aaccttgtgg
     9481 atgctgaaac tggcgaaatt ttggtagaag ctggaactga gatgactcgt agcgtcatcg
     9541 aatccatcga agaacacctt gacggtgatt tgaacaagtt tgtttacaca ccaaatgatt
     9601 acgctgtggt tactgaacca gttgtccttc aaaagttcaa ggttgtgtca ccaattgatc
     9661 ctgatcgtgt agtaactatt gttggtaatg ccaatccaga tgataaggtt cgtgcattga
     9721 cacctgctga tattttggca gaaatgtctt acttcttgaa ccttgctgaa ggtcttggaa
     9781 aagttgacga tattgaccac ttgggtaacc gtcgtatccg tgccgttggt gaattgcttg
     9841 ccaaccaatt ccgcatcggt cttgctcgta tggagcgtaa cgtgcgtgag cgtatgtctg
     9901 ttcaagacaa cgatgtgtta acaccacaac aaatcatcaa tatccgtcct gtcacagcag
     9961 ctgtcaaaga attcttcggt tcgtctcagt tgtcacagtt catggaccaa cacaacccat
    10021 tgtcagagtt gtctcacaaa cgtcgtttat ctgccttagg acctggtggt ttgacacgtg
    10081 accgtgctgg ttatgaggtt cgtgacgtgc attacacgca ctatggccgt atgtgtccga
    10141 ttgaaacacc tgaaggacca aacattggtt tgattaataa cttgtcttca tttggacatc
    10201 ttaataaata tggtttcatc caaacacctt accgtaaggt tgaccgtgcg actggtacgg
    10261 taactaacga gattgtttgg ttgactgccg acgaagaaga cgaatacaca gttgcacagg
    10321 ccaattcgaa actaaacgaa gatggcactt ttgctgaaga aatcgttatg ggtcgtcacc
    10381 aaggtaataa ccaagaattt tctgcaagtg ttgttgattt cgttgacgtt tcccctaaac
    10441 aggtagttgc tgttgcgacg gcatgtattc ctttcttgga aaacgatgac tccaaccgtg
    10501 ccctcatggg tgccaacatg caacgtcagg ctgtgccatt gattgatcca aaagcaccat
    10561 atgttggtac tggtatggaa tatcaagctg cccatgactc aggcgctgcg gtgattgctc
    10621 agcaaaatgg taaagttgtc ttttctgatg ctgaaaaagt ggaaatccgt cgtcaagatg
    10681 gctcgcttga tgtttaccac attaccaaat tccgtcgttc aaactcagga acagcctata
    10741 accaacgcac ccttgttaaa gtaggagaca ttgttgaaaa aggtgatttc atcgctgatg
    10801 gaccttctat ggaaaatggt gaaatggctc ttggacaaaa cccagtcgtt gcttacatga
    10861 cttgggaagg ttataacttt gaggatgccg ttatcatgag tgagcgcctt gtgaaagaag
    10921 atgtctacac atctgttcac ttggaagaat tcgaatctga aacgcgtgat acaaaacttg
    10981 gccctgaaga aatcactcgg gaaatcccaa atgttggtga agaagccctc aaagaccttg
    11041 acgaaatggg cattatccgt atcggtgctg aggttaaaga aggcgacatc ttagtaggta
    11101 aagtcacacc taaaggtgaa aaagaccttt ctgctgaaga acgtttactt cacgccatct
    11161 ttggggataa atcgcgtgaa gtgcgtgata cctcacttcg tgtccctcac ggtggtgatg
    11221 gtatcgttcg tgatgtgaaa atctttacac gcgctaacgg cgatgaattg caatcaggtg
    11281 ttaatatgct tgtgcgtgtt tacatcgctc aaaaacgtaa aatcaaggtc ggagataaaa
    11341 tggccggtcg tcacggaaac aagggtgtcg tttcacgtat tgtaccagtt gaagacatgc
    11401 cataccttcc agatggaaca ccagttgaca tcatgttgaa ccctcttggg gtgccatcac
    11461 ggatgaatat tggtcaggtt atggaacttc accttggtat ggctgctcgt aatcttggta
    11521 ttcacattgc aacacctgtc tttgacgggg cttcatcaga agacctttgg gacactgttc
    11581 gtgaagctgg tatggatagc gatgctaaga cggtccttta tgatggtcgc accggtgaac
    11641 catttgacaa ccgtgtatcc gttggtgtca tgtatatgat caaacttcac cacatggttg
    11701 atgataaact tcatgcccgt tctgtaggac catactcact tgttacccaa cagccacttg
    11761 gtggtaaagc tcaatttggt ggacaacgtt ttggtgagat ggaggtttgg gcccttgaag
    11821 cttatggtgc atcaaatgtt cttcaagaaa tcttgaccta caagtcagat gacgtcacag
    11881 gacgtttgaa agcctatgaa gcgattacta aaggtaaacc aattccaaaa ccaggtgtac
    11941 cagaatcctt ccgtgttctt gtaaaagaat tgcaatcgct tggtcttgat atgcgtgtgc
    12001 ttgacgagga tgataatgaa gtggaacttc gtgatcttga tgaaggtgaa gacgatgaca
    12061 ttatgcatgt tgacgatctc gagaaggcac gtgaaaaaca agctcaagaa actcaagaag
    12121 tttctgaaac aactgacgaa aaataagcaa tcaattctta ttaaataatt atttactggt
    12181 ctggggcaaa ggccccagga actggtaaag tcatcaaagg cagaaaggta aaactagtgg
    12241 ttgacgtaaa tcgttttaaa agtatgcaaa tcacattagc ctcaccaagt aaggtccgtt
    12301 catggtctta tggtgaagtt aaaaaacctg aaacaatcaa ctaccgtaca ttaaaaccag
    12361 aacgtgaagg actctttgac gaagtcatct ttggtccaac aaaagactgg gaatgtgcgt
    12421 gtggtaagta caaacgtatc cgttataaag ggatcgtttg tgatcgctgt ggggttgagg
    12481 taactcgtgc taaagtacgt cgtgaacgta tgggtcacat tgagttaaaa gctcctgtat
    12541 cacatatctg gtatttcaaa gggattccat ctcgtatggg attgactctt gatatgagtc
    12601 ctcgtgccct tgaagaagtg atctattttg cggcttatgt ggtcattgat ccaaaagata
    12661 caccgcttga accaaaatca ttattaacag aacgtgaata ccgtgaaaaa ctacaagagt
    12721 atggtcatgg gtcatttgtc gctaagatgg gtgctgaagc cattcaagat ctcttgaaac
    12781 gtgtggactt ggcagctgaa atcgctgaat taaaagaaga gttgaaatct gcttctggtc
    12841 aaaaacggat taaagcagtt cgtcgtttag acgtccttga tgcctttaac aaatctggaa
    12901 ataaaccaga atggatggtt cttaacatcc tgccggttat tccaccagat cttcgtccga
    12961 tggttcaatt ggatggtggt cgttttgcgg catcagactt gaatgacttg taccgtcgtg
    13021 tgattaaccg taataaccgt ttggcacgtt tgttagaact taatgcccct ggcatcattg
    13081 ttcaaaatga aaaacgaatg cttcaagaag ccgttgatgc tttgattgat aatggtcgtc
    13141 gtggtcgtcc aatcactgga ccaggaagtc gtccattgaa atcattgagc cacatgctta
    13201 aaggtaaaca agggcgtttc cgtcaaaact tgcttggtaa acgtgtagac ttctctggac
    13261 gttccgttat cgctgttggt ccaaccctta aaatgtatca atgtggtgtc ccacgtgaaa
    13321 tggctatcga gctttttaaa ccatttgtaa tgcgcgaaat tgttgccaaa gaatatgctg
    13381 gtaacgttaa agccgctaaa cgtatggttg aacgtggcga cgaacgcatc tgggatatct
    13441 tagaagaagt tatcaaagaa cacccagtcc tacttaaccg cgcaccgact cttcacagac
    13501 ttggtattca ggcttttgaa cccgttctta ttgacggtaa ggcacttcgt cttcacccac
    13561 ttgtgtgtga ggcctacaat gccgacttcg atggagacca aatggccatt cacgtgccac
    13621 tttcagaaga agcacaagct gaagctcgtc ttttgatgct tgctgcagag cacatcttga
    13681 accctaaaga tggtaaacca gttgttactc catctcagga tatggttctt ggtaactact
    13741 atcttacgat ggaagatgct ggtcgcgaag gcgaaggtat gattttcaag gataaagacg
    13801 aagctgtgat ggcatatcgt aatggttatg ctcatcttca tagtcgtgtg ggtatcgctg
    13861 ttgacagcat gccaaacaaa ccttggaaag acaatcaaag acataaaatc atggtgacaa
    13921 ctgttggtaa gattctcttt aacgatatca tgccagagga ccttccttac ctccaagagc
    13981 caaacaatgc caacttgaca gaaggaacac ctgataaata cttccttgaa cctggtcaag
    14041 acatccaaga agtgattgat cgcttagaca tcaatgtgcc atttaagaag aaaaacctcg
    14101 gtaacatcat tgcggaaacc ttcaaacgtt tccgtacaac agaaacatca gccttccttg
    14161 accgcttgaa agaccttggt tactaccact caacccttgc tggtttgaca gtgggtatcg
    14221 ctgacattcc tgttattgat aataaagctg aaatcattga tgctgctcac catcgtgttg
    14281 aagaaattaa caaagccttc cgtcgtggtt tgatgacaga tgatgaccgt tatgttgccg
    14341 ttacaacaac atggcgtgaa gctaaagaag cccttgaaaa acgtctgatt gaaacacaag
    14401 atcctaagaa cccaatcgtt atgatgatgg actcaggagc tcgtggtaac atctcaaact
    14461 tctcacagct tgctggtatg cgtggtttga tggctgctcc taacggacgc atcatggaac
    14521 ttcctatctt gtcaaacttc cgtgaaggtt tgagcgtttt ggaaatgttc ttctcaaccc
    14581 acggtgcacg taaagggatg accgatacgg cccttaaaac agccgactca ggttacctta
    14641 ctcgtcgttt ggttgacgtt gcccaagatg ttatcattcg tgaggacgat tgtggcactg
    14701 atcgtggtct tcttatccgt gctattacag atggtaaaga agttaccgaa acgcttgaag
    14761 agcgtcttca aggtcgttac acacgtaaat cagtcaaaca ccctgaaact ggtgaagtct
    14821 tgattggtgc tgaccaatta atcactgaag acatggctcg taagattgtt gatgcaggtg
    14881 ttgaagaagt gaccattcgt tctgtcttta cctgtgcgac tcgtcatggt gtctgccgtc
    14941 actgttatgg tatcaacttg gcaactggtg atgctgttga agtgggtgaa gcagttggta
    15001 ctattgctgc ccaatctatc ggtgagcctg gtactcagct taccatgcgt accttccaca
    15061 cgggtggtgt agcctcaaat accgatatca cccagggtct tcctcgtatt caagagatct
    15121 ttgaagcacg taatcctaaa ggggaagcgg tcattactga agtgaaaggg aatgtcgtcg
    15181 agattgaaga agatgcgtca actcgtacca agaaagtcta cgttcaagga aaaactggca
    15241 tgggcgaata tgtcatacca tttacagcac gtatgaaagt tgaagttggc gacgaagtta
    15301 atcgcggagc tgcccttaca gaagggtcaa ttcaaccgaa acgtctcctt gaagtgcgtg
    15361 ataccttgtc agttgaaacg taccttcttg cagaagtaca aaaagtttac cgtagccaag
    15421 gggtagaaat cggagacaaa cacgttgagg taatggttcg ccaaatgctt cgtaaagttc
    15481 gtgtcatgga tccaggtgat acagacctcc ttccaggtac acttatggat atttctgatt
    15541 tcacagatgc taacaaagat attgttatct ctggtggtat tcctgcgaca tctcgtcctg
    15601 ttcttatggg tattactaag gcttcccttg aaaccaattc cttcttatca gctgcatcct
    15661 tccaagaaac aactcgtgtt cttacagatg ctgctatccg tggtaaaaaa gatcatcttc
    15721 ttggtcttaa agaaaatgtt atcattggta aaatcatccc agctggtact ggtatggctc
    15781 gttaccgtaa cattgaacca caagcgatga atgagattga agtgattgat catacagaag
    15841 tctcagcaga agccgttttt acagcagaag cagaataatc tcatgaaagg gtccttaggg
    15901 gctctttttt gtctgagttt gttggcagta aaaagcattg acaatcagtc ttagtcccaa
    15961 tgagcagatg tttttcaaaa tacttatgat ttagctataa taatgcataa gaggaatggg
    16021 taatgtgtta tgtatcaagt aattaaaatg tatggtgatt gggagccttg gtggttcatc
    16081 gatggatggc aagacgatat tatagatgag caacaattta gtgactggca agaagcgctt
    16141 gattatttta atcaagaatg gcagcgcatg aaagctattt ttcctagtta tcatagtcaa
    16201 aagaatttgt tagctacttt ttgggaaaaa gaagataaaa gatggtgcga ggactgtgac
    16261 gaagatttgc agcagtttca ttctctttta ctccttaaaa ataaagatat tgtaccaagc
    16321 aataattata tccctgaatt tgaacaacga aatgattcac cacaggtagc ttatctttgc
    16381 aagttaaacc tttaagtgtt tgttaaaaac aaaataagtt aaaagaaaat atcacttctt
    16441 ctgatatttt ctttttttgt ttacgaataa atgagtaagg aggaattatg gtacaagcat
    16501 tagcaaaagc tattctagca aaagctgaac aggttcatgc acaagatatt tatattttgc
    16561 caagagcaga tcaatatgat ctttttttac gaataggaga tgaaaggaga ttagttgatg
    16621 tttatcagag cgatcggatg gctcctctta ttagtcactt taaattcgtt gcaggaatga
    16681 tagttggtga aaagagacgt tgtcaggtgg gttcatgtga ttataagctt agtaaagata
    16741 agcagttatc tttgcgctta tctagcgtgg gtgattatcg cgggcaagaa agcttagtga
    16801 ttcgtctgct tcatcatcaa aataaaagtg tacattattg gtttgatgga ttgacaaaag
    16861 tagccaatca ggttggcggt agagggttgt atttatttgc aggaccagtt gggtctggga
    16921 agacaacctt gatgtaccag ctgatttcga attatcatca agaagcacag gttattagta
    16981 tagaagatcc tgtagaaatt aaaaatcacc aaattttaca attacaagtg aatgatgata
    17041 ttggtatgac ttatgacaat ttgatcaaac tgtctttacg ccatcgacca gatattttag
    17101 ttattggtga gattcgagat agtcaaacag caagagccgt tattagggct agtctaacag
    17161 gtgccatggt tttttcaacg gttcacgcta aaagtatctc gggtgtttat gcaagattgt
    17221 tagaacttgg tgtaacgaaa gcagaactgt ctaattgctt agcattaatt gcttaccaaa
    17281 ggttacttaa tggaggagca ttgattgact ctactcaaaa cgaatttgaa tattattcct
    17341 catcgaactg gaatcaacaa attgatcagc ttcttgaggc aggacatctc aatcccaagc
    17401 aagctaagct tgaaaaaatt atctagtaaa catcagcata aattcattca attactagct
    17461 aatcttttat ctacaggatt tagcttcgca gaggttattg cttttttaaa aagaagccag
    17521 ttgcttcagc tagattatgt tcttaaaatg gaagagtctt tattaaaagg acaaggctta
    17581 gcagatatgt tgtcgggttt aggtttttca gatgctattc ttactcaaat tagtttagct
    17641 gatagacacg gtaatattga aacaacatta gtagcgattc aacattactt gaaccaaatg
    17701 gcaaggatca gacgaaaaac tgttgaagtt atcacctatc ctcttattct tttacttttt
    17761 ctttttgtga tgatgctagg gttgagacgc tatttagtcc ctcaattaga aactcaaaat
    17821 cagataactt actttcttaa ccattttcct gccttcttta taggtttttg ctcaggtctt
    17881 attttgttgt tcgggatggt atggctacga tggcgatctc aaagccgctt gaaactctat
    17941 agtcggctaa gccgttatcc ttttttaggt aaactgttaa aacaatactt aactagttat
    18001 tatgctagag aatggggtac gttaataggt caaggtcttg atttgatgac tattttagac
    18061 attatggcca ttgagaaatc ctcactaatg aaagaattag ctgaggacat cagaatgagt
    18121 ctgcttgaag ggcaagcctt tcacattaaa gtagctacct accctttttt taaaaaagaa
    18181 ttaagtttaa tgattgaata cggtgaaatc aaatcgaaac tgggggctga gttggaaatc
    18241 tatgcccagg aaagctggga acaatttttt agtcagcttt atcaagtgac acaacttatt
    18301 caaccagcta tttttttagt agttgctgtg acaatcgtca tgatttatgc ggcaatccta
    18361 ttaccaattt accaaaatat gggaggtatt ttttaagatg attaatcaat ggaacaactt
    18421 acgacacaag aagctaaaag gatttactct tctagaaatg ttattggtga ttcttgtcat
    18481 cagtgttttg atgctattat ttgtgcctaa tttaagcaag caaaaagaca gggttacaga
    18541 aacaggtaat gccgctgttg ttaaattagt ggagaatcaa gcagaactat atgaattatc
    18601 tcaaggctca aaaccaagtt tgagccagtt aaaggcagat ggtagtatca ctgagaaaca
    18661 agaaaaagct tatcaagact attatgacaa acataaaaat gaaaaagccc gtcttagcaa
    18721 ttaaagcttt tactttgctt gaaactttac taagtttgtc agtgatgagt ttcattatat
    18781 tgggattgtc tgtaccagtg acaaaaagct atcaaaaagt agaagagcat ctgtttttta
    18841 gccattttga acatttgtat cgacatcagc aaaagttagc catattacag caaaaacagc
    18901 gcgtcttgga tatttcttca acaaaaattg ttacagaagg taatagccta acagttccta
    18961 aatcaataac agtgaatcat ccttatcggt tagttattga tcagatggga ggcaaccatt
    19021 ccttagctaa aattattttt gacatgactg atcgacgctt taaataccaa ttttatctag
    19081 ggagtgggaa ttatcaaaaa acaagtcaaa gcttacatag cccttgaaag tatgatcgca
    19141 acaggcatcc tctttagtat tgtcattctc gtcttaagca gtttacagca gagtcaggct
    19201 gctctaacgt actatcgaaa gcagcaagaa aagcttaatc tagccttgat ggcagtacaa
    19261 actagaacta aagagatgac attgaatggt tgtcatatta ctattttacg tacggataga
    19321 tacattagta ttcacgatga cgaaggagaa gtgatgaaga ttgagtaaac aattaagtaa
    19381 cataaaagct tttacccttc tagaggcgtt aatagcctta ctcgtgatat cagggtcttt
    19441 attggtttat caaggtttga cccgaaccct ccttaaacat agccattatc tagcccgtca
    19501 tgatcaagat aattggctct tattttctca tcaattgcga gaggagttaa gtggagcaag
    19561 gttttacaaa gtagctgata ataaactata cgttgaaaaa ggaaagaaag tactagcttt
    19621 tggccaattt aaaagtcatg attttcgaaa atcagctagt aatggaaaag ggtatcaacc
    19681 catgttattt ggaatatcac gtagtcatat tcacatagag cagtcacaga tttgcattac
    19741 tttaaagtgg aaaagtgggt tagaaaggac tttttattat gcctttcaag actaatctca
    19801 aagcaggcat ccttttgtat gctatgttta tggctagtat ttttttgctg gttttacagg
    19861 tttacctttc tcaagtgaca gctctacaca aggaatacca agctcaaact gactatgtta
    19921 aagcccgact gatagcagaa atagtttatc aagatcatag atataaagct tctaatcctg
    19981 tcttttttaa aggtggtcaa gtcatttgtc gagagcgaaa agagagatgg atgttaattg
    20041 ttaagttaga tcagcaacga cagtatcagt ttgaatacct taaacccaaa caatatagtc
    20101 aataaatagt attgttgtca taaatcctta aaatgatcca atatatagta attaaaggtg
    20161 acacttcttt tcatttcaag tgtaatttgg tatgataagg ttatgacttt tgaaaaaatt
    20221 gaagaagctt atcagctgct cttagagaac tgtcaactaa ttgaaaatga tctaaaaaca
    20281 catatatacg atgccattgt tgaacaaaac tccttttatt taggggctga gggagctagt
    20341 cctcaagttg ctcaaaatag tgataaactg aaagccttgt gcctgacaaa agaagaatgg
    20401 cgtaaggcct accagtttct ttttattaag gcagctcaga ctgagcaact ccaagccaac
    20461 catcagttca caccagatgc tattggcttc attctgctgt atcttttgga acaattgagt
    20521 gataaagata gcttagaggt acttgagatt ggaagtggaa cagggaacct agcccaaacc
    20581 cttctcaaca acacgagcaa gagccttgat tatgtaggga ttgaacttga tgatctcttg
    20641 attgatctgt cagccagtat tgctgagata atggattctt cagctcattt tattcaagaa
    20701 gatgcggtaa ggcctcaatt actaaaagaa agtgacattg tcatcagtga cttaccagtt
    20761 ggttattatc ctaacgatga tattgccaaa cggtacaagg tggctagttc agataagcat
    20821 acctatgccc atcatttatt aatggaacag tctttaaaat acttgaaaaa agacggtttt
    20881 gcgatttttc tggcaccagt caatttattg acgagccctc agagccagtt gttgaaacag
    20941 tggttaaaag attatgctca ggtggtgacc ttgattacgc taccagattc tatttttggt
    21001 catccctcaa atgccaagtc cattattgtc ttacaaaaac aaacagacca cccaatggaa
    21061 acctttgtct atccaattcg ggatttgaag cttgcagaga atattcatga ttttatggaa
    21121 aatttcaaaa aatggaaact gagtaatgtc aattaattga ttttttgtta taataaaaaa
    21181 gcatcacaga aaacgatttc aagagaggtt aaaaatgtca aagacaattg caattaatgc
    21241 aggtagttct agtttaaaat ggcaacttta tcagatgcca gaagaagcag tgttagcaca
    21301 aggaattatt gagcgtatcg gtctcaagga ttctatttca acagttaagt acgatggcaa
    21361 aaaagaagag caaattcttg atattcacga tcatacagaa gctgttaaaa tcttattgaa
    21421 cgatttgatt cactttggaa tcattgcagc ttatgatgaa attacaggag ttggacaccg
    21481 tgttgttgct ggtggtgaac ttttcaaaga atccgttgtg gttaatgaca aagttcttga
    21541 acagattgaa gaattatccg ttttagctcc acttcacaat cctggagcgg cggcagggat
    21601 tcgtgccttc cgtgatattt tgccagatat taccagtgtt tgtgtgtttg acacgtcatt
    21661 tcacactagc atggcaaagc atacttacct ttacccaatt cctcaaaaat attatacgga
    21721 ctacaaggtt cgtaaatatg gggcgcatgg gacaagtcat aaatatgtag cgcaagaagc
    21781 tgctaaaatg cttggtcgtc cattagaaga attaaaacta attactgctc atattggaaa
    21841 tggtgtctca attacagcta attaccacgg taaatcagtt gatacctcga tgggctttac
    21901 accacttgct ggtcctatga tgggaacacg ttctggtgac attgacccag ctatcattcc
    21961 ttatttaatt gagcaagacc cagagttaaa agacgctgct gacgttgtta atatgttaaa
    22021 caaaaaatca ggtcttagtg gggtgtcagg catttctagt gatatgcgtg atatcgaggc
    22081 tggtttacaa gaagataatc cagatgctgt tttagcttac aatatcttta ttgatcgcat
    22141 taaaaaatgc attggtcaat attttgctgt tttgaatgga gcagatgctt tggtctttac
    22201 agctggtatg ggtgaaaatg caccattgat gcgtcaagat gttattggtg gcttaacatg
    22261 gttcggaatg gacattgatc ctgagaaaaa tgtttttgga taccgtggtg acatttcaac
    22321 tcctgagtca aaagtgaagg tgcttgttat ctcaacagac gaagaattgt gcatcgcgcg
    22381 tgacgttgaa cgtttaaaaa atacaaaata aaagagacta agtctcaata gattaaccaa
    22441 gtaaggtaac actttacttg gttttttatg aggtttatct gttggttatg gtgcctaggt
    22501 attagttctg atcagtctcc ttgctttttg taatcttgtg ctaggcgatt tggatgtcag
    22561 ccttatttag aagtttttaa ttgcttcaac gcttttcttg tatgtgttta tagagcccaa
    22621 tgatctaaaa gactatttga taacggttta tgatgagcgt aatcgtgcga ttcgaaaaca
    22681 gacacaagtt tactgctttt acctgatgat tgttctattt gttgccttat tctttttctt
    22741 cccttgctta accattcgag atcttgtttc ttataagcta cctttgattt ttgcttacct
    22801 ttacttgatt atcagaagtc tggtggctaa gaaaatggag gcactaggga aaataacaac
    22861 taatagtcaa aaacctccgt ttgatacgag tcaggttctt tgttagatga cttgtctaac
    22921 ggttgagttt cctgtctggt caacggaggt gtttgtattg ttgtctgatt tgtattgggg
    22981 cacttatttt acaagctttt agctttatcg atggttttgt caatggcaga gctgacagta
    23041 gctgtgaggc caaggcgttc taactccatc agaccagcaa tagttgtgcc accggggcta
    23101 caaatagcgt caatgaaatc gtgcggactt tgagaactgg tcttgagatt gctggcgcta
    23161 gccaatactg tttgagtaac aatctccagc gcctttgctt taggtatgcc attcttgacg
    23221 ccagccttag ccaaagcctc aataaagaga taaatatagg caggacttga ccctgctaaa
    23281 gcggtaaagg tgtcaaaatc cttttcacta atatcaaatg tgctaccaaa gctatctgtt
    23341 aagtctcgaa cacgtgcttg taattcctgg gacaccaaag catttcccgt taaagcggta
    23401 ctgctttgga gaatttgtgc attcatgttt ggcatgatac gtagcagcgg aaggtcttgt
    23461 cctacgaatg ttgctagtcg ttgaagggaa atgcctgctg ccatagatat aataggctgt
    23521 ttgaagtgaa gcggtttgag taccgtttca aatagttgag gcttgatgcc taaaataaca
    23581 agatcaacct ggtcaataag gtcttggtgg gacatagcat aaggcagtgc taactgctcc
    23641 gcaatttcct tggaccgttc taaagatgat cctgaaatga taagttcatg gggtgtttgt
    23701 ttaaggcctt tgatgatagc gctagccatt ttgccaacac caataatgcc aattttcatt
    23761 ctgttgctcc ttgtgggata ttatggttaa tcaggctaat gctagtttag taacatttaa
    23821 tcaagtcaac ggttgagcga tccagttttt tgataatggc ttgtaagaag gcttgggctt
    23881 ctacgaaatc atccatagcg tagagggttt gatgagagtg aatgtagcgt gcacagactc
    23941 cgatggttgt tgatgggaca ccaccatttt gaaggtgtgc agcacctgca tctgtgcctc
    24001 ccttgccaca atagtattgg aaattgacac cagcttcctc agcagtagtc agtaagaagt
    24061 cgcgcatatc tttgagcatg acatggcctg ggtcgtagaa acgcaacaag gtaccatctc
    24121 cgattgttcc aggattgcca taaatatcac cagcaggcga acaatctact gcgaaaaaga
    24181 gttcagggtc gaacttggtg gttgagacgt gggctccgcg cagaccaact tcttcttgaa
    24241 cgttagcacc tgcaattagg gtgttgttaa ggtcttgtcc ttttaacgct tcaagcattt
    24301 ctgttatcat gagaacgcca tagcgattgt cccaagcttt tgaaataata tttttttgat
    24361 tggctgttag gattgtttca gattgaggga taataatatc acccggtgta ataccaaatc
    24421 tttcagcttc tgccttatcc gtaaagccac catcaaacac aatatcttcg atatgtggta
    24481 gactagcaga gccatttgcc ccacgtaaaa aatggggagg taccgatcct gaaataaggg
    24541 gaataacttg gccagtgcgt gtgtaaaggg taaaccgttg tgaactgaca acaagtgggt
    24601 tccaaccacc gataccaacc acgcgtagcg ttccgtcaac tttgatatca ctgaccataa
    24661 aaccgacttc gtccatgtgc gcagctacta aaatacgggg ggctttttca gctttactat
    24721 ctctgatacc aaaaatgcca ccaagcccgt ctgtttcaac acggtcaacc agcggggtta
    24781 ttttggtgcg taggtagtca cgaacgctat gttcatagcc cgcaatgcca tccagttcgg
    24841 taacttcttt gatttttgag aataagtctg tcatttttca tctccattta aaaggtttca
    24901 gaccagttca acgcggtcat ctccttatat tctaccactt tttaagtaag aatgggtttc
    24961 acagaaaaga aaaatcccag agactagaga tctctggaag aagtgtttgt cttttggcga
    25021 taacctgttt ttttaggcag caaggaaatc attaaaatga taaagcacaa gctggttaat
    25081 aagaatagta gggcgcttag gatgcgaaaa gactcttcac tagcgaaaag taaggataat
    25141 ggagtcataa ggagaacctt ccattttagg ttaatcagtg atttttatag cgtggttaaa
    25201 ttaataataa accacaccta atcaacgtac ctttagttta gttgttttta ctatttttgt
    25261 caatacataa cagtagaaat ctttagtttt cttatttcag atcgtccaat ttgatctttt
    25321 tatgataaaa tgagggatat gagtaaaaag aaaataggta tgatttcagg tatctttgga
    25381 tttagtttag ctattggcct aggaatagtt atcaaagatt attgccaaga caggcagcgt
    25441 cgacaaatga caagggattt acgcaccttt ttttcacctt taggacaaat cgaagtttta
    25501 tatatcaatc cttgtcaggt caaacaagat tatatttcag gtggggttgt tatgtcaaac
    25561 ggcaaacagt accaattcac ctatcacagt cgacaaatta gttttgagga ggacaaggga
    25621 tgatcagacc gacttcttat gagtcattag cgactcttat tgaaaaagaa gataagctgg
    25681 tgttattttt tacggcagac tggtgtccag actgtcaatt tatttatcct attatgccag
    25741 aaattgaagc agaacttaca gatatgactt ttgtttgtgt taatcgtgat cagtttatag
    25801 aggtagcaca aaagtggaat atttttggta ttcctagttt tgtcgtgatt gaaaaaggtc
    25861 aggaagtagg gcgtctggtt aacaaaatga gaaagacaaa aactgagatt atgcattttt
    25921 tagctgctta tcaataagaa aagaggaaga ataaatgatt tttgcataca ataaagaaca
    25981 agttggcgat gtcttgatgg ttatcttaca agacaccaaa gatatcaaac gtcaagtaga
    26041 acgaaaaggc aaagtagccc gtgtttttgc agaagaaagc ggcaaaaccc ttgcttggaa
    26101 tatctttgaa gcgtcaagct tgattactat tgaaggcaat ggacagattt ttttgacaga
    26161 cgagaacctt gcaagattaa atgcagagct tgctaaggaa ggattttcag aaaggcttga
    26221 accgattgtg ggacctgttt ttgtggttgg tcaaattgtt gagatggtgg ctcatccaga
    26281 tagcgaccat cttaatatct gccaagtggc tattggtgaa gatcaaacgg ttcaaatcgt
    26341 agcgggcgca ccaaatgctg cacttggttt aaaaacgatt gttgccttac caggtgctat
    26401 aatgccaaat ggtagtctga ttttcccagg aaaattgcgt ggtgaagaaa gttatggtat
    26461 gatgtgctct cctcgtgagt tagccttgcc aaatgcaccg caaaaacgtg gcattattga
    26521 atttgatgag tcagctgtgg taggagaagc ttttgaccca gccaaacatt ggaaaggtta
    26581 gaaaaaccag ctgaaataag actgtattta actaaatgac cagaaaaaaa ggattaggag
    26641 cccttaatcc ttttttctta tgttttcaaa aacgtttaaa atgaaactta ttttaccaca
    26701 atttttacga ataataagat aaggaggtca gtatgtataa taaagtgata gcaatcggtc
    26761 gtttggtagc taaaccagaa ttggtaaaaa cagctacgga taagcatgta gcacgtctct
    26821 ctttagctgt taatcgaaga tttaaaaatg cttctggaga gcgagaagct gattttattt
    26881 cagttgttgt ttggggaaag ttagcagaaa ctctggtttc ttatgctagc aaaggtagtt
    26941 tgatgtctat tgatggcgaa cttaggaccc gcaagtatga taaagatggg caagtgcatt
    27001 atgtgacaga agttctctgc caatcatttc aactgcttga aagtcgtgct cagcgcgcta
    27061 tgagagaaaa taatgttact aatgatctag ttgatttagt cttagaagaa gatactcttc
    27121 ccttttgata gaggataatg cttctcatca gggttcagct gattactgaa atatatgatg
    27181 aggtgatatc cgaacaacaa aagtgtgact agatacttct gataaaaata aaaaaacacc
    27241 ttacgagtat gaacaaagtt tcaagtgcta gatgttggaa ctttgttcat cataggaata
    27301 gtagggtgtt ttttagtgta ttacttcttt ttgttgctag tgttaaggtt tacttgctta
    27361 caagcggtta tcaggccact agaactctta taataaatgg agctctttga gtttggtgtc
    27421 aatcattttt aagacagtcg ccaaatcttg tgggttttga acgaagtcaa gggaattgcc
    27481 atcaattttc atttttggag agacctcgta gtcttcgtac caggttgggt attcaccgtg
    27541 gacttgatgg taatattgct caagactagg attgccgtcg acctgctcaa aacttcggcc
    27601 acgtctttca atgcgctcaa gcattttgtc aaaagacaca tcaatgtaga tgagaagatc
    27661 agggcgtttt ttaggcatgc cttctagttc ttctaacatg ttggcgagaa gttcctgata
    27721 gatgtcaagt tctgtcttag tgacattgcc atttttgtag ttaagtttta agaagagttc
    27781 gtcttcaaaa atagagcggt caagaatgtt gttatcggct tgataagctt ctttgatgga
    27841 cttaaatcgt ttattcaaaa aataaatttg aagtaaaaag gcgtattttt tagggtcttg
    27901 gtagtagagg tctagcacgg ggttattatc aacagcttcg taaaaaacgt cagttcctaa
    27961 atgctctcca agtgcagcag caagcgagct cttgccagcc ccaattgttc cagctagtac
    28021 aatcaacatg cgtctccttc taatatcatt agcgtactgt ttcgaagatg gcttcaacct
    28081 cagctagagt ctcagcgcgt gaaacagcac cacgaacttt ggcagcacct gctgttccgc
    28141 gaagatagtg tggtgctaag ccccgaaatt cccgaacagc aatggtttca cctttgaggt
    28201 taatcaggcg tttaaggtgg tctttggcga tgtctaattt tttggcaaag ggaagatctg
    28261 gcaattcttg accagtttca aagaaatgat tgatttgggt aaaaagataa ggattgttca
    28321 tggctgcgcg gccaatcatc acggcatcta caccgatttc ttcaatcata aatttggcgt
    28381 cttgcaccga acgcacgtcc ccatttccaa taaagggaat cttagtgata gccttagaaa
    28441 ctcgggctaa tgtctcatgg tcgcaggttc ctgtatacat ttgttcacgg gtacgaccgt
    28501 gcatggcaag agcagataca cctgccgact cagcggcaag ggcattttca acagcaagtg
    28561 aactatccgc ccaacctgta cgcattttga cagtcagtgg aatatctaaa acagacgtga
    28621 cttccttgac aatgtggtaa atcttatcag ggtcacggag ccacttggca ccagcctcgt
    28681 ttttgacaac tttattaaca gggcagccca tattaatatc aacaatatcg gccttggtat
    28741 tggtttgaat gaaatcagct gcacgtttca acccttctgc gtcaccacca aataattgaa
    28801 tggacatagg gtgctcattt tcatcaatat ggagcatgtg aagggtcttt tcattgttgt
    28861 aaagaagccc tttttcggaa atcatttcca taaccaccaa accagcacca aattctttgg
    28921 cgatggtacg aaaggcagaa ttggtcacgc cagccatggg agcaaggaca gtgcggtgag
    28981 ggatttccac atcaccaatc ctaaaggaag aattaagctt tatcactgat aatggcctcc
    29041 aaatcacttt cattaaattg gtacttggta ccacaaaatt ggcaaacaat ctcagcaccc
    29101 ttatcttcgt caatcatggc ctgtaaatct gcttttggca aagtcattag ggctgcttca
    29161 aaacgttctc tagaacagtc acactgaaaa ctcagaggtt cttcagaaag acgcttgtaa
    29221 ggttcatctc catagatggc ctccaaaagg gcatccacat gatttttgga agctagtagg
    29281 tgagaaatgg caggcatttc ttgcaggcgt ttttcatagc gagcaatctc ttcttcagaa
    29341 gcgcctggta gcacctgcac cataaagcca ccagcaacct taaccttatc attttcatct
    29401 aaaagcacat taagtccgat tgcagatggt gtttgctctg attcggttaa gtagtaggca
    29461 aaatcctcac caatttcccc agtaataaga ggcgttgttg aggtgtaagg gttacctgtg
    29521 ccataatcaa taatcgtcac aaaatgacca ttccccataa aaggcccaac aaggacttca
    29581 cctgttgcgg tctttttaat atcgacacca gtattttgaa tgtaaccttt cacatgtcct
    29641 ttggtatctg ccacagagat aatgtgtcca aaagaagaat caccaatcac tttgacggtg
    29701 attttactat cgcctttttg attagccgcc aaaatctggt tggcgatcaa ggtacggcca
    29761 agcgcaacag tagacgatga cagcgtgttg tgtttttctt gagctaatgc aaccgtctca
    29821 gtgctatcaa ggacataagc cctaaaagcc cctgattgtg ctattgattt aattatttta
    29881 tccataactt agattatagc ataaagtgta aaacttgtat tgacaggatt gcttgaaaaa
    29941 tcaatacaga tagacagtaa aaaatcccag agaatgactc gggattaagt taaggtgtgg
    30001 tctaaagtcg cgcaatgtgg tgacatggcg cttatgttaa ttgcttggtt aaatcagctt
    30061 ggaatttttc ctctttaact tgatacatca attcttggat agacagaatc gattcatcaa
    30121 aagatatttc agcaacagca attccttttg taagttcatg gtgaacaaaa ggaatcagtt
    30181 gactgtgagt gatgaccaaa tctggcttta aatcaggaat ttgataaaca ttatcttgca
    30241 atagataata ggaatgaaaa tcaatgcttt tatccgagaa ataccttgga aaagaatccg
    30301 ttaggagatg agcattgata aaattactgg ctacgaaaac aacaactaaa ggaggttgga
    30361 tatttcttag actttgctcg acatagtggc aaaaaagatg aaaatgctta tggttcaagt
    30421 cacgcttacc aggaagtttg gccatccact cttcgacaat taactttaag gacgtataga
    30481 gtttttggtt tcctttatag tacggagaaa cgaataagtt ggtctcagga ataaaatgtt
    30541 gcagattaaa caagaatgat tttgaaaaaa acataagagc ttttactaaa ctagcctttt
    30601 gctcttttag gttaggtaaa agagtgatga taggatttaa aagcaggcga aaagtatcat
    30661 tttcttcaaa aagttgacaa tattgtctga tatgctcagg tgtccattgt aagctcgcaa
    30721 aagaattatt agcggtgata taaattaaat agaggtagtc caaatctcct gctgaaaagt
    30781 ttagttggca gtaagtttcg ataatatcat ggctactttt tttcaaagaa tcgtagacaa
    30841 aaagtttttt taattgttga aaaattctgg tttggggaat agttaccgaa aattgatgcc
    30901 gcttccacga taaagctaat aaaatgtcat agaaagaaaa cgattccgat aaccaaggag
    30961 aggttttaag gtgggtggaa ctatgggata aaaagctatg aatagtgttt ttgtcttgct
    31021 gcgtcaagtc ataaacttta atgccaaact tactatatag cagagcgatg aggtaacgga
    31081 tgcgatattc ctcaccgaca atcttgttct tagagagttt taattcaaag tttcttaata
    31141 aaggaatcaa tgcttcgcgc atccgataag ctgaggagtt tgataaaaaa tgacttcttg
    31201 caaaatccgt aaggggacga gagtgggaac cattttttat taaaaaggct agtaattgta
    31261 agacattaga tgatgcatag agttggtaaa gataagtttc tttaaaagga tgtgtaaatt
    31321 ggcaagatat catccttttt tggatggtca tagacagact accagggaaa aaggcattca
    31381 gttcctcaca ataatggttt agttgtaaaa aggttaagcc agttttttct gctacctcag
    31441 ttattggcaa ataagatgtc ttaaaaaaca agacaattaa ctgacatttt gattcgattg
    31501 atgattccaa gtatttttct atcaaggaaa gggacctctc ttcctacact tagaaagcca
    31561 aataagtctt tgataagtgt attctcctat ttcaattcta tctaagctaa aaatagaagt
    31621 caaatctaat ggtttttggt aaaaagtcga aaccttttga aatagcttta aagcaatatt
    31681 ttctcaaaaa atcattttca aaaacactaa tttggtgaaa aacttagtac gaatatattt
    31741 ctttgacttc aatagaatga tatgatgtca cattgagagg agagaaaatg aaaaaaacaa
    31801 ggtttccaaa taagcttaat actcttaata ctcaaagggt attaagtaaa aactcaaaac
    31861 gatttactgt cactttagtg ggagtctttt taatgatctt cgctttggta acttccatgg
    31921 ttggtgctaa gactgttttt ggtttagtag aatcctcgac gccaaacgca ataaatccag
    31981 attcaagttc ggaatacaga tggtatggat atgaatctta tgtaagaggg catccatatt
    32041 ataaacagtt tagagtagca cacgatttaa gggttaactt agaaggaagt agaagttatc
    32101 aagtttattg ctttaattta aagaaagcat ttcctctcgg atcagatagt agtgttaaaa
    32161 agtggtataa aaaacatgat ggaatctcta caaaatttga agattatgcg ataagcccta
    32221 gaattacggg agatgagcta aatcagaagt tacgagctgt tatgtataat ggacatccac
    32281 aaaatgccaa tggtattatg gaaggcttgg aacccttgaa tgctatcaga gttacacaag
    32341 aggcggtatg gtactattct gataatgctc ctatttctaa tccagatgaa agttttaaaa
    32401 gggagtcaga aagtaacttg gttagtactt ctcaattatc tttgatgcgt caagctttga
    32461 agcaactgat tgatccgaat ttggcaacta aaatgccaaa acaagttccg gatgattttc
    32521 agctaagtat ttttgagtct gaggacaagg gagataaata taataaagga taccaaaatc
    32581 ttttgagtgg tggtttagtt cctactaaac caccaactcc aggagaccca ccaatgcctc
    32641 caaatcaacc tcaaacgact tcagtactta ttagaaagta tgctataggt gattactcta
    32701 aattgcttga aggtgcaaca ttacagttga caggggataa cgtgaatagt tttcaagcga
    32761 gagtgtttag cagtaatgat attggagaaa gaattgaact atcagatgga acttatactt
    32821 taactgaatt gaattctcca gctggttata gtatcgcaga gccaatcact tttaaggttg
    32881 aagctggcaa agtgtatact attattgatg gaaaacagat tgaaaatccc aataaagaga
    32941 tagtagagcc ttactcagta gaagcatata atgattttga agaatttagc gttttaacta
    33001 cacaaaacta tgcaaaattt tattatgcaa aaaataaaaa tggaagttca caggttgtct
    33061 attgctttaa tgcagatcta aaatctccac cagactctga agatggtggg aaaacaatga
    33121 ctccagactt tacaacagga gaagtaaaat acactcatat tgcaggtcgt gacctcttta
    33181 aatatactgt gaaaccaaga gataccgatc ctgacacttt cttaaaacat atcaaaaaag
    33241 taattgagaa gggttacagg gaaaaaggac aagctattga gtatagtggt ctaactgaga
    33301 cacaattgcg tgcggctact cagttagcaa tatattattt cactgatagt gctgaattag
    33361 ataaggataa actaaaagac tatcatggtt ttggagacat gaatgatagt actttagcag
    33421 ttgctaaaat ccttgtagaa tacgctcaag atagtaatcc tccacagcta actgaccttg
    33481 atttctttat tccgaataac aataaatatc aatcccttat tggaactcag tggcatccag
    33541 aagatttagt tgatattatt cgtatggaag ataaaaaaga agttatacct gtaactcata
    33601 atttaacatt gagaaaaacg gtgactggtt tagctggtga cagaactaaa gatttccatt
    33661 ttgaaattga attaaaaaat aataagcaag aattgctttc tcaaactgtt aaaacagata
    33721 aaacaaacct cgaatttaaa gatggtaaag caaccattaa tttaaaacat ggggaaagtt
    33781 taacacttca aggtttacca gaaggttatt cttaccttgt caaagaaaca gattctgaag
    33841 gctataaggt taaagttaat agccaagaag tagcaaatgc tacagtttca aaaacaggaa
    33901 taacaagtga tgagacactt gcttttgaaa ataataaaga gcctgttgtt cctacaggag
    33961 ttgatcaaaa gatcaatggc tatctagctt tgatagttat cgctggtatc agtttgggga
    34021 tctggggaat tcacacgata aggataagaa aacatgacta gagctgattt cagaacttct
    34081 aattcatctg gagaacttaa caaactatca ttttcagata aagaagcaat aaagccctta
    34141 ctcataggac ttgttaaaaa aatagccctt attcttattg gcggctatct actttttcac
    34201 tttgtttttg gatttatgat tatcaaaaga aacgatatgg ctcctagtgt aaaagcagga
    34261 gatgctattt tattttatcg cttatctcag acttataaag tagaagaagc agttgtttat
    34321 gaggactcta aaacatctat aacgaaagtc ggtcggatta ttgctcaagc aggtgatgaa
    34381 gtggacctga cagaacaagg tgaattaaaa attaatggcc atattcaaaa tgaaggacta
    34441 acttttataa aatcaagaga agctaattat ccgtatcgaa ttgctgataa tagttatttg
    34501 atactcaatg attactatag ccaagagagt gagaattacc tacaagatgc aattgctaaa
    34561 gatgctataa aaggcacgat taatacactt attcgattaa gaaaccatta agctaaaggc
    34621 ttatttaaaa aaggagagaa acaatgaaat tacgtcactt actattaacg ggagcagccc
    34681 taactagttt tgctgctaca acagttcacg gggagactgt tgtaaacgga gccaaactaa
    34741 cagttacaaa aaaccttgat ttagttaata gcaatgcatt aattccaaat acagatttta
    34801 catttaaaat cgaacctgat actactgtca acgaagacgg aaataagttt aaaggtgtag
    34861 ctttgaacac accgatgact aaagtcactt acaccaattc agataaaggt ggatcaaata
    34921 cgaaaactgc agaatttgat ttttcagaag ttacttttga aaaaccaggt gtttattatt
    34981 acaaagtaac tgaggagaag atagataaag ttcctggtgt ttcttatgat acaacatctt
    35041 acactgttca agttcatgtc ttgtggaatg aagagcaaca aaaaccagta gctacttata
    35101 ttgttggtta taaagaaggt agtaaggtgc caattcagtt caaaaatagc ttagattcta
    35161 ctacattaac ggtgaagaaa aaagtttcag gtaccggtgg agatcgctct aaagatttta
    35221 attttggtct gactttaaaa gcaaatcagt attataaggc gtcagaaaaa gtcatgattg
    35281 agaagacaac taaaggtggt caagctcctg ttcaaacaga ggctagtata gatcaactct
    35341 atcattttac cttgaaagat ggtgaatcaa tcaaagtcac aaatcttcca gtaggtgtgg
    35401 attatgttgt cactgaagac gattacaaat cagaaaaata tacaaccaac gtggaagtta
    35461 gtcctcaaga tggagctgta aaaaatatcg caggtaattc aactgaacaa gagacatcta
    35521 ctgataaaga tatgaccatt acttttacaa ataaaaaaga ctttgaagtg ccaacaggag
    35581 tagcaatgac tgtggcacca tatattgctt taggaattgt agcagttggt ggagctcttt
    35641 actttgttaa aaagaaaaat gcttaaatta ttattatgat agtaagactg attaagctcc
    35701 ttgacaagtt gataaacgtc attgttcttt gtttcttctt tctttgttta ttgattgcgg
    35761 cacttggaat ctacgatgct ttaacagttt atcaaggagc taatgctact aactatcaac
    35821 aatataagaa aaagggtgtt cagtttgacg atttattagc tattaattct gatgttatgg
    35881 catggctgac tgttaaagga acgcatattg attatccaat tgtacaggga gagaataatt
    35941 tagaatatat caacaaatca gtagaaggag agtactcctt atcaggaagt gtttttctag
    36001 attatcgtaa taaagtaact tttgaagata aatactcatt aatctatgca catcatatgg
    36061 ctggaaatgt tatgtttggc gaattaccta actttaggaa aaaatcattt tttaataaac
    36121 acaaagaatt tagtattgaa accaaaacaa agcaaaaact gaaaatcaat atttttgcat
    36181 gtatccaaac agatgctttt gacagtttac tgtttaatcc aattgatgtt gatatttcta
    36241 gtaaaaatga atttttaaac catatcaagc aaaaatcggt acagtatcgt gaaatattga
    36301 caacaaatga aagtcgtttt gttgccttat caacctgtga ggatatgaca acagatggta
    36361 ggattatcgt tattggacaa attgaataat tgtaagagaa aggaggtcat atgaaaaaat
    36421 ctatattaag aattttagct attggttatt tacttatgag tttttgtttg ttagactccg
    36481 tagaggcaga gaacctcact gcaagcatta atattgaagt tattaatcaa gttgatgttg
    36541 ctaccaacaa acaatcctct gacatagatg aaacgtttat gtttgtaatt gaagcgttag
    36601 ataaagaaag tcctttacct aattcggtaa ctacttctgt taagggaaat gggaaaacat
    36661 catttgaaca gttgactttt tcagaagttg gacaatatca ttataaaatt catcaactgt
    36721 taggtaagaa tagtcaatat cattatgatg aaacagtata tgaagttgtt atttacgtat
    36781 tgtataatga gcaaagtggt gctttagaaa ctaacctagt ttctaacaaa cttggagaaa
    36841 ccgaaaaatc ggagcttatt tttaaacaag aatatagtga aaaaacaccg gaacctcatc
    36901 aaccagatac aactgagaag gaaaaacctc agaaaaaacg taatggtatt ttgccatcaa
    36961 ctggtgaaat ggtgagttac gtatctgctt taggaattgt cttagtggct accattactt
    37021 tgtattctat ttataaaaag ctaaagacaa gcaaatagat tcaattttaa gcagagtaat
    37081 tctccttgag gatttaggaa agatatgtaa gaaaaaccaa aaattccttt acttaatgat
    37141 aaaggaattt tttattgccc cacgacagca aattgttcgt aagcgtccaa taacaaggta
    37201 tattgaaaac ctccaaagtt tctaattgac tctggaggtt ttgattattg acaatttgtt
    37261 tgtacttttt tagcccatgg caaataagct tctagcactt ctcttttagc gagagtttct
    37321 tcattaggaa ggcggtctag aaggtagcta atatattttt cggagttcag tccatgtcgc
    37381 ttagccgttt caagcaaact catgatgata gctgccgctt tggctccttc aaaactttga
    37441 gaaaacaacc aattttttcg gcccatcact aaggatttga tagctctctc tgccatattg
    37501 ttagacagaa caatatggcc atcctctaaa acagttctaa aggttctttc atgcttgaga
    37561 ctataagcga tagcgagacc cagcttcgat cctgaaagga caacttgctc gcgacaccaa
    37621 tcaaagaagg tggtcattaa tggcgtcaag atttctttgc gtttaaccag acgctcttga
    37681 gggggtaact cacaccattc agcttctaag gcgaacaact tgtcacagta aacaagtcct
    37741 ttacgcccta gagaagtctt atcagcttgc ttcggggtgg cctcaaagaa cttccgcctc
    37801 acatgtgccc aacaaccaac aagcttggca tgctctaatt gacgataagc cccatgcata
    37861 tcacaatgca cataacctga gtaatcgccg agaacctctt gagtaacgag gccgctacgc
    37921 cttttatcat gatggtaaag ggtaatccct tttttctcat gcttaccaga caaaaaagtc
    37981 cagtaatagg tcaactgagt gtcactttca agaactctat aagatgtctc atccgcatga
    38041 atgacctctt gacttaataa gatgtcacga agcaagtcat aaagaggctc aaaataatac
    38101 tggctagact tgatatgcca gttagcgatt tccttgcgac taatggacag tcctaattta
    38161 ttccaatcct cttcctgtct gtagttagga actttaaggg tgaatttttg atgaacggta
    38221 tgggcaataa tagaagccga accaaggcta tgagctaatg gtgccttagg aacaggcgct
    38281 ttgatgatct tgtcactgag gctattatcg ctacaagttt ggcacttata agcgtgttgc
    38341 acatgattta tacgtttcaa ttgtgctggg ataaagacta attcttgacg ttgaaccacc
    38401 gagccaattt ctgtcaatgt tccatgacaa tccggacaag tacagctgtc accaattaat
    38461 tcgtggtgaa caagctcagg ttcaaattga gctagaatag cttgacgtct tcctttgatt
    38521 ttcttgcgtc tataagtaat gtcttctgtt tctactgggc aagtcatccg cttcttctgg
    38581 taattggtcc tggtcaaaga gactgagttg accggtcata ggcatagctt tttcagaaga
    38641 tttcccataa agcttttgag ttaaataagc cacttgttca cgcaggaggg ctagctcatt
    38701 agccattgtt tcaatggttt tggcttgtgt tttaatgact ttatcttgtg aactcatggt
    38761 cttcctcctg atattttctt cattatacct gaagaaaagc catgagttca atagaaatca
    38821 tgactttttg aaatttttat gttaggacta atgaaaaatc ccttcataag ccagtccacc
    38881 tgtacagctg tcaagcattt gacctcatcc ctatttcttg gccaggctag tttcccattt
    38941 tcaaagcgtt tataaagtaa ccagaaacct tgaccatccc agtaaagcgc tttgaaccga
    39001 tcacgtcgcc caccacagaa gagataaaca gcacctgaaa agagatctaa ctcatgttgg
    39061 gatttgacaa gataggctag ggaatcaatg ccttgtcgca tatctgtttt tccacaaacc
    39121 agataaactt gtcctaggtc atttagccga atggtcatcg ttcagtacct tatccaaaat
    39181 gctttccaac aagtcctgat tgagtgcttg aaataaacta agttccagtt ttccaaggcg
    39241 aactttaagc aagatatcat ttctgttttt ttctcaaatc gacgagattg gggaacttcc
    39301 aaaggaacaa tagggtgtga tatttaaatt atcctccgat agactagttt tactaacagt
    39361 atactggagg attgagaatc acggtagata ccctgttatt ggacgcttac attattttta
    39421 ttgggaacag ccatttttct ttaccctacg ttaagtagtc agtggaatgc tatcgtgatc
    39481 gtcaattgtt atcaacttat cacaaacaag tgactcaaaa gaagccctca gaaatggagg
    39541 aggtgtggca aaaggctaag gcgtataacg ctaggcttgg gattcagcct gttccagatg
    39601 ctttttcatt tagggatggc attcatgata aaaactacga aagcctactt caaattgaaa
    39661 acaatgatat tatgggatat gttgaagtgc cctctattaa agtgacgtta cccatatacc
    39721 actatacgac agacgaggtg ctaactaaag gagcaggtca cttatttgga agtgccttac
    39781 cagttggtgg tgacgggact cacacggtta tttctgctca tagaggcctt ccatcggcag
    39841 aaatgtttac taatttgaat ttagtgaaaa agggagatac tttttacttt cgtgtgttaa
    39901 ataaagtatt ggcttataaa gttgatcaga tactaactgt tgaaccagat caagtcacat
    39961 cactttctgg agtcatgggg aaagattatg ctactttggt tacctgcaca ccatatggtg
    40021 ttaacaccaa gcgtctattg gtccgaggtc atagaattgc atatcattat aaaaagtatc
    40081 aacaggctaa aaaagcaatg aaactcgtgg ataaatcaag aatgtgggca gaagtagtgt
    40141 gtgctgcttt cggggtggtt atagctatta ttttagtgtt tatgtattcg cgagtaagtg
    40201 ctaagaaaag caagtgatag ttaaataaga gattgtaata gaaactggtg gactttgccc
    40261 accagttttt tggggtacgg tggggatatc gtacagaaga gctccttcgg ttactttaag
    40321 tataataaaa gaaataaaaa gagtctgagc aatcatgttg tcttagactc tgactgtatt
    40381 atgcaaaaga tgatggactg gcagcttcat ttactcaccg aattcccctt tataacttgg
    40441 gaatgatgct gctaatgggt tgttttgttt aatacctgct ataaacggta atttatccca
    40501 tttatttttg taattatctt caagctcagt tttaaacttc caaaccattt tatgagaaaa
    40561 ataagtgtgt gattgacggc cataggtatc tactaaaacg tgagaaaatt ttccgtcgtt
    40621 ttttagtttg taaaatttat ctagagaagg actccaacca gtataaccag ggaatttatc
    40681 aaattcttga ttaaaatttg tttgttggct tttccaatca taatgccatt gtgtattatt
    40741 gcgtgtttca gaacgaactg taccgtccca ataatgatgc tcataagtta tctctgtagg
    40801 agcttttaca cccttaggaa gaaaaactga gaaatcaggg taaacccatt gttctttagc
    40861 tgaattaaag gttacagtcc attcaatatt tttatcgcta tcgaccaatt ttttagtata
    40921 gtcgacatag ttatcaacat agtaatttcc ctgccagtaa aggtgcactt tacctttctc
    40981 atcaatgtta tcatgggcat gtactgattt atacgaacta aacagcatcg aagctgctag
    41041 tagtgaagtg aagagatatt tattacatcg tttcatatca tgaaaaacc
//
LOCUS       DAUGJR010000013        41054 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUGJR010000013 DAUGJR010000000
VERSION     DAUGJR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41054
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.013"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..174)
                     /locus_tag="VH800_000685"
     CDS             complement(<1..174)
                     /locus_tag="VH800_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8361764.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVD"
     gene            complement(243..314)
                     /gene="shp3"
                     /locus_tag="VH800_000686"
     CDS             complement(243..314)
                     /gene="shp3"
                     /locus_tag="VH800_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEQ8361765.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            394..1245
                     /gene="rgg3"
                     /locus_tag="VH800_000687"
     CDS             394..1245
                     /gene="rgg3"
                     /locus_tag="VH800_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEQ8361766.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1498..5037)
                     /gene="smc"
                     /locus_tag="VH800_000688"
     CDS             complement(1498..5037)
                     /gene="smc"
                     /locus_tag="VH800_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEQ8361767.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQCTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEVALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLIRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGANRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5038..5730)
                     /locus_tag="VH800_000689"
     CDS             complement(5038..5730)
                     /locus_tag="VH800_000689"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEQ8361768.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6174..6983)
                     /locus_tag="VH800_000690"
     CDS             complement(6174..6983)
                     /locus_tag="VH800_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8361769.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(6987..8339)
                     /gene="vicK"
                     /locus_tag="VH800_000691"
     CDS             complement(6987..8339)
                     /gene="vicK"
                     /locus_tag="VH800_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEQ8361770.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWIEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8332..9042)
                     /locus_tag="VH800_000692"
     CDS             complement(8332..9042)
                     /locus_tag="VH800_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8361771.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9204..10238)
                     /locus_tag="VH800_000693"
     CDS             complement(9204..10238)
                     /locus_tag="VH800_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8361772.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFTLDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISHHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10294..11541)
                     /locus_tag="VH800_000694"
     CDS             complement(10294..11541)
                     /locus_tag="VH800_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ8361773.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLKKADFAVL
                     SSGTTGKAKLFWRRLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(11498..12646)
                     /locus_tag="VH800_000695"
     CDS             complement(11498..12646)
                     /locus_tag="VH800_000695"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEQ8361774.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNTVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLSGASDQGIRPRLSSKVLSKVPPILGEG
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13041..13190)
                     /locus_tag="VH800_000696"
     CDS             complement(13041..13190)
                     /locus_tag="VH800_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEQ8361775.1"
                     /translation="MQLLDNVYGTLRSFAFMRPAKSSNDTSLADALQAGTDMAFILVR
                     GINYQ"
     gene            complement(13391..14176)
                     /locus_tag="VH800_000697"
     CDS             complement(13391..14176)
                     /locus_tag="VH800_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361776.1"
                     /translation="MAKLRCMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFCLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESADS"
     gene            complement(14178..14996)
                     /locus_tag="VH800_000698"
     CDS             complement(14178..14996)
                     /locus_tag="VH800_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEQ8361777.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGSSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(14998..15990)
                     /locus_tag="VH800_000699"
     CDS             complement(14998..15990)
                     /locus_tag="VH800_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8361778.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQYYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHEFSLDIQYDSSRYQTADIIQKTMADFAVRDVKMTDVDIEDIVRRFYRKEL"
     gene            complement(16131..18074)
                     /gene="thrS"
                     /locus_tag="VH800_000700"
     CDS             complement(16131..18074)
                     /gene="thrS"
                     /locus_tag="VH800_000700"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEQ8361779.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKTTHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(18496..19830)
                     /locus_tag="VH800_000701"
     CDS             complement(18496..19830)
                     /locus_tag="VH800_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8361780.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGNGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19832..20830)
                     /locus_tag="VH800_000702"
     CDS             complement(19832..20830)
                     /locus_tag="VH800_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8361781.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20961..21962)
                     /gene="ccpA"
                     /locus_tag="VH800_000703"
     CDS             complement(20961..21962)
                     /gene="ccpA"
                     /locus_tag="VH800_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEQ8361782.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22136..23221
                     /locus_tag="VH800_000704"
     CDS             22136..23221
                     /locus_tag="VH800_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8361783.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLVKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23270..23935
                     /locus_tag="VH800_000705"
     CDS             23270..23935
                     /locus_tag="VH800_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8361784.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SIGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23946..24323
                     /locus_tag="VH800_000706"
     CDS             23946..24323
                     /locus_tag="VH800_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8361785.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24468..25394
                     /locus_tag="VH800_000707"
     CDS             24468..25394
                     /locus_tag="VH800_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8361786.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25605..26288
                     /locus_tag="VH800_000708"
     CDS             25605..26288
                     /locus_tag="VH800_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEQ8361787.1"
                     /translation="MEWIKLIGIVIIVLGFILKCDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQALTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26288..27214
                     /locus_tag="VH800_000709"
     CDS             26288..27214
                     /locus_tag="VH800_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEQ8361788.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27264..27911
                     /gene="pcp"
                     /locus_tag="VH800_000710"
     CDS             27264..27911
                     /gene="pcp"
                     /locus_tag="VH800_000710"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEQ8361789.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28027..28746)
                     /locus_tag="VH800_000711"
     CDS             complement(28027..28746)
                     /locus_tag="VH800_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEQ8361790.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28752..29219)
                     /gene="smpB"
                     /locus_tag="VH800_000712"
     CDS             complement(28752..29219)
                     /gene="smpB"
                     /locus_tag="VH800_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEQ8361791.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29222..31555)
                     /gene="rnr"
                     /locus_tag="VH800_000713"
     CDS             complement(29222..31555)
                     /gene="rnr"
                     /locus_tag="VH800_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEQ8361792.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPIRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNIDRLTQSALMEINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKIIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYNQPSQEKRDHFAQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVSSVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31649..31885)
                     /gene="secG"
                     /locus_tag="VH800_000714"
     CDS             complement(31649..31885)
                     /gene="secG"
                     /locus_tag="VH800_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEQ8361793.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31931..32077)
                     /gene="rpmG"
                     /locus_tag="VH800_000715"
     CDS             complement(31931..32077)
                     /gene="rpmG"
                     /locus_tag="VH800_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8361794.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32074..33267)
                     /locus_tag="VH800_000716"
     CDS             complement(32074..33267)
                     /locus_tag="VH800_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEQ8361795.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPVRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33389..34891)
                     /locus_tag="VH800_000717"
     CDS             complement(33389..34891)
                     /locus_tag="VH800_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEQ8361796.1"
                     /translation="MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLAIIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISELGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYKLLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHAFRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
                     QAATKKANRRSVGRSHKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35081..35674)
                     /locus_tag="VH800_000718"
     CDS             complement(35081..35674)
                     /locus_tag="VH800_000718"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEQ8361797.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR"
     gene            complement(35671..36498)
                     /gene="mutM"
                     /locus_tag="VH800_000719"
     CDS             complement(35671..36498)
                     /gene="mutM"
                     /locus_tag="VH800_000719"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEQ8361798.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRL"
     gene            complement(36670..37536)
                     /gene="rgg2"
                     /locus_tag="VH800_000720"
     CDS             complement(36670..37536)
                     /gene="rgg2"
                     /locus_tag="VH800_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEQ8361799.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37625..37693
                     /gene="shp2"
                     /locus_tag="VH800_000721"
     CDS             37625..37693
                     /gene="shp2"
                     /locus_tag="VH800_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEQ8361800.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38607..38876
                     /gene="stcA"
                     /locus_tag="VH800_000722"
     CDS             38607..38876
                     /gene="stcA"
                     /locus_tag="VH800_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEQ8361801.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPILKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39224..39622)
                     /locus_tag="VH800_000723"
     CDS             complement(39224..39622)
                     /locus_tag="VH800_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEQ8361802.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRDVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     gene            complement(39715..40710)
                     /locus_tag="VH800_000724"
     CDS             complement(39715..40710)
                     /locus_tag="VH800_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361803.1"
                     /translation="MRQIQSIRLIDVLELAFGVGYKEETTSQFSSDQPSQVVLYRGEA
                     NTVRFAYTNQMSLMKDIRIALDGSDKSLTAQIVPGMGHVYEGFQTSARGIFTMSGVPE
                     STVPVANPNVQTKYIRYFKVIDDMHNTMYKGTVFLVQPQAWKYTMKSVDQLPVDDLNH
                     IGVAGIERMTTLIKNAGALLTTGGSGAFPDNIKVSINPKGRQATITYGDGSTDIIPPA
                     VLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQSLNEHEAMVNVEPLSHVVKDNIKVI
                     DEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVGSWLEPATALPSVEMSAEDRLKS"
BASE COUNT        12364 a         8727 c         7200 g        12763 t
ORIGIN      
        1 gtctaccaaa atttttttat gtttatattc atccagaact cctatgttgt gatttagata
       61 ttcaaataat tcatctgata tagaatgttc aactggatta ccaagcaatg cagaatacat
      121 aaatttcatc ctcctacgtt taattagttt actactaaca taaagtacaa gcattacaca
      181 gagctaacca ttacctataa gtctttagat actctaaaga cttaagtgta cacctaagta
      241 acttacccac caacaataat gataatatcc attgctaaaa ttaaaatcgg caaaaatttt
      301 gaaattttct tcataagcgg acttcctttc agtttttatt tattgtacaa taaaaaaaaa
      361 cggaattgat ttttgttggg aaagtgggaa aatatgaaat caaaacttgg tgccacactt
      421 agaaaagttc gaaaaggaaa gcaaattagt ctgtgcttcg tggcagatga acacctttca
      481 aaatcacaaa tctctcgttt tgagcgcggg gagtcagaga tatcgtgtat ccgactgatc
      541 aatattctag acaaattaca cattactttg gatgagtttc ttattttaca tgatgaagac
      601 tataccaatt ccgaaacatt tgctaacctg gtacagtata ttcgtaagca atattcatca
      661 caaaatatca ataatatagc atgtttactt tccgacactt ctgattacac tctgaattct
      721 tttgagaaaa caatggtaaa gtccatttta cacacaatgg attcaagcat cattccatca
      781 gatgatgaat tacttcaact aacagattat ctctttaaag ttgaaaaatg gggctactat
      841 gaaatccttt tgttgggtaa ctgtgtacga acaattaact acaactccta cttcctattg
      901 acaaaggaga tgttaaataa ttacatttac tcttcacgga acaaaactaa taaacgaatt
      961 gtcactcagc ttgctataaa ttgtttcatt cttagtatca ataaggagga attttctaat
     1021 tgctcctatt taattgatga gataaaaacc ttgttagata atgaattaaa cttctatgaa
     1081 cagacagttt ttctctatgc aacaggttac tttgaattta agcgccaatt agaaactgga
     1141 gttgaaaaga tgaaacaagc catacaagtt cttgatattt taaatgaaga caagttaaaa
     1201 ttacattacg ctgaccattt tgataaacta gtcaacaaag attaagtaaa atcattcttt
     1261 accttttaac gaaacgccaa tcaagggtgt ctcaataaaa aatcatctac tctgacaact
     1321 tttctctttt acctatcgac agctaaaaag ccttggaaac tgctatttcc aaggctttct
     1381 ttgtactcta ttgtatcaat tagcttattc cgatttctgt tgctattagt ttaatcatga
     1441 aatctcctaa cttatggccg aacatccaaa aaaacagaag gaactccctt ctgtttttta
     1501 attggtcatc tcttgagctt cttttaattt tacagataca attttagaga cccccgattc
     1561 ctgcatggta attccataaa tactatctgc tgcagccatt gttcctttac gatgggtcac
     1621 gacaataaat tgactatctt tgtcaaagcg attgaggaaa tccccaaagc gcttaacatt
     1681 tgcttcatca agagccgctt ctacctcatc taaaatcaca aacggaatcg ttttaacacg
     1741 tataatagca aacaataaag ccagtgctga caaagctttt tctccgcctg acatcaagtt
     1801 aagagattga attttcttac caggaggctg cacagaaatc tctataccag cagacaagag
     1861 gtctgtttcc gttaaaacca aatcagcaga acccccacca aacatctgag taaaggtttc
     1921 tttaaaactt ttttgaattg cctcaaaagt cactttgaaa cgagccttca cttcgctatc
     1981 catactatta atagtctcta gcaaaagatt tttagctttt gtcagatctg tcttttgact
     2041 tgttaaaaaa gtcaaacgct catgcacttc ctcatactga ttaatagcat cactattaat
     2101 tggtcctagt gcacgaatag tcttttgtaa atggtgtaat ttttctttgg cactttctaa
     2161 gtgatcaata ctatttgtta cctcctttgc gtctgctagt gtcatttgaa aatcttctga
     2221 taaactttta gcataggctc gtaagcgatt agccacttgc tctaaatgtg tctctaactt
     2281 ggtttgacga cgaataaatg tgtcattttt ttcgctttct ttggttattt tttctgctgt
     2341 ttcttctaag cgggcctcat agtcctctat ttcaaatctt aattggacta aacgtttttg
     2401 agcaccagac ttatgctctg tggcatcttg taactgtttt tgccactggg gtagtctttg
     2461 aatgctgtct tgacttacgt tattgtttag tatgctttca agtttgagaa tattttgctg
     2521 gcattgcttc agctgagttc ttagacgaga ttgattagct tgctcaaatt tcttttcatt
     2581 aagtaaatct ctttcttgca aacgagcttg agataaagct tggtgaatgt tttgtgtttt
     2641 ttgcctaatc aaatctttgt tttctttgat atcatcaata tcacaagtta aggcattttt
     2701 tttcttagca atagctgtta atgcttcttc aatacgagct tgttctgcca ataaagattc
     2761 atcagaatga gtcgtctgac tttggtcaag ggcagctaac aaagcctttg aatcttcttg
     2821 tttttcttgc aattgctgat aagccatttg agctctttgt tcagctaagc gtgcctggtc
     2881 accggctaat ttcaattgtg tcagttcttc tttttttgct atcaaatcgc tttgcaaggc
     2941 agctacttct ttttcagtta tttttaattg ctcaactaat cgcgttaatt cctcactgat
     3001 ttgttctaac tctggtttga taaaagttgt attgctttgt ctattagctc ctcctgaaaa
     3061 agaaccacct ggtcgtaatt ctgttccatc aagagtaaca attcttacct tatatcctaa
     3121 taagcgcgct gcaatattag cttgatcaat agtttcaaag atagcagtac tagataaaag
     3181 attttggata atagctgaaa gactatcatc atagcgaatc aatgattctg cagttcccag
     3241 ataaccttca caagtcgcca attgacgatg atagtgttct gataatgatc tagcctttat
     3301 agtagttaaa ggtaaaaaag ttgctcgtcc ttggcgattt tttttcaaat aagcaattgc
     3361 tctttttgct gcagcttcgt ctgttacaat aatatgctga ctattagcac ctaatgcaac
     3421 ttcaagagct gtttggtaat cagaatcaaa agaaaggtgt tcactgactg cacctatgat
     3481 ccctccaagc tttttttgtg attgaaggac agctcgtact cccgcataga attgactatg
     3541 acttttttga atagattcta agctagcctt acgagcttct tttccttttt tttgatccaa
     3601 caagtcaaat agtctttctt gattcagttg gtaatctctt tctaattcct gaacgcgttt
     3661 atcaccttct tgataatttt ggagcaacat ttcgacttgc tctttttgag ctttataatg
     3721 agcttgagct ttttgagact cgtcattaag ttgatcaagc ttagtaacaa gtagctgata
     3781 ttcttgagcc ttatgttgac gagcctgttt ttctttgtct aaatgggctt ttaaagctgt
     3841 cagctgattt gataaggccg cctctttttg catcaataat acaaactctt ctcttagagt
     3901 ttccattaat tggtcgggat cacttgaaaa acgctctaat gcattgctca attcgtttaa
     3961 ctgttgtttg acatcacaaa gttgttgatc aatatgcaat aattgttctg tacactgctt
     4021 ttcttctgct tgaaaaccat ccaattgttc ttgtaactgt tcgagatgtt ttttggcttc
     4081 tgcctttttc tctgcttctt ggccactttc tagcttaacc aattcaattt gcttttccaa
     4141 gtcagctatt agcttggtta attctaataa tgttgtttgg gtttgatctg actcttgact
     4201 aagaacctgc tttttttgct tgaatttttg gtaatcttct tccatagatt gacgcttagc
     4261 gtaataagat gctaagtctt gttgtaaagc agctaaagct tcagtatctt tagtctgtct
     4321 ttcttgagct atatcaatat ctttgactag aatatctagt tgtagttgct tacgattggc
     4381 atcaagttct aaaaattgtt tagctacttt agcttgcttt tcaagtggtg ccaactgcgt
     4441 gtctagctca taaataatat cctctagacg gtctaaatta tcttgagttt gatttaattt
     4501 aatctgagtt tcttttttac gtgttttata ttttaaaaca ccagctgctt cttcaaaaat
     4561 ggcgcgcctt tcttcaggtt tactattgaa aatttcctct acgcgacctt gagaaataat
     4621 ggagaaagaa tcacgaccaa gccctgtatc cataaacaaa tcatgaatat cacggagcct
     4681 taccttgcga ccatcaatca gatagtcact atctccattt cggtaaatat gcctttcgac
     4741 acggatttct ttcttggcag tttttataaa atgatcggaa ttatcaagaa caaccgctac
     4801 cttagcatag tttagaggat tacggttttg tgtcccagca aaaatgacat ctggcatctt
     4861 gcccccacgc agatttttag cacttgattc tcctaaagcc caacgtaaac tttctgtaat
     4921 attactttta cctgaaccat ttggtcctac gactgcagtt actcccttat caaattcaat
     4981 tttagtcttg tccgcaaagg acttgaaccc ttccaactca atttctttta aaaacatcta
     5041 aacctcacta agttgggcaa gggcattttt agcagcatct tgctccgcta attttttaga
     5101 cttacctaaa cctttactaa ggacagcacc attaacaact atcgatacct caaattgttt
     5161 agcatgggca ggtcctttct cactaatgac ttgataatca atagccacat caccttttgt
     5221 ttgcaaaaac tcttgaagac aagttttata gtctttaacc ctttcaaaat tccctttttc
     5281 cacctgagga atcatgactt gtttcaagaa gcgacgtact gcatcaatcc ccttatctaa
     5341 taaaagagca cctaaaaagg cttcaaataa gtctcctaaa atagtatcac gacggcgacc
     5401 acctgacttt tcctcacctt ttcctagttt gatataagcg tcaaaagaac aaaatcgtga
     5461 aaaacctgcc aagctttcct cacgtacaat catggaacgt aacttagaca tatctccttc
     5521 tgtcttttta ggatactttg caaataaata ctctgaaata atcaattgta gaacagcgtc
     5581 tcctaaaaat tccaagcgtt cattatgtga aacgtttagg agacgatgct cgttagcgta
     5641 agaggtgtgg gtaaaagctg tttctagtaa agtcaaatca ttaaattgaa tatcaaaaga
     5701 tgttgagagt aactcttcaa gctgtttcat aaaaaatccc tttcatattt gtcagtagac
     5761 cttatttagt ataccaaaaa tccacctaga aaaccgactc taagtggatt tttcgtgatt
     5821 tattaaacat cttaaatacc cgtcaaagga aactttctca tacaatcaaa agactctaca
     5881 ctatctgagg ggaatttccc actacagtcc cactacagat agtatagagc tatttttgtt
     5941 tttagtctga acaactaaaa aactacctca tctttataat cctcaacacc tttgataaat
     6001 agatcagaca agccaaaact acaggctaat ttaagtctat tgatgctcta aaggatgacc
     6061 aatgagagtt cgttgaactc agaagacaat acgctttaag acatcaaaaa atagccctga
     6121 ctggtatatc accaatcagc gctactttgc atattctctt ttagtttctt atctcaaata
     6181 tcagttaatg gacaagcagt atctggagag gtatcatgga ccgtaaagtc tgtacctact
     6241 gctaaatctg ccatagccag ttgattgacc atcgtcatat gcgctaactc tttgatgtta
     6301 ttttctttac tcagatgacc taggtatatt tttttggtat tgtaccccag gcttctaatc
     6361 atggctcccg ctccatcttc atttgataaa tgtcctaaat cagataaaat acgctgcttt
     6421 aagctccaag gataagagcc tgatctcaaa atttcaatat catgattgga ttcaatcaag
     6481 tagccatctg cattttcaat aatacctgtc atcctatcac tgacatatcc tgtatctgtc
     6541 aacatcacaa aagacttatt atctttcata atccgataaa attgaggatc aatagcgtca
     6601 tggctgactc caaaactttc gatatcaaca tctccaaagg tcaaaacttt atccctttgg
     6661 aaaatatgtt tttgtgaggc atcaagctta cctagcatat tgcactcatc catcagctgc
     6721 catgtttttt cattagcata gatatccaaa tggtatttgc gggccataac gcctacaccc
     6781 ttaatatggt cagagtgctc atgggtaatc aaaatagcat ccaaatcctc aggtttgcgg
     6841 tcaatttcag caagaagact ggtaattttc ttaccagtaa gccctgcatc aatcaataag
     6901 cgttttttag gtgtttctaa ataaaaacaa tttcctgtgg acccagatgc taaaatactg
     6961 tatttaaaac cactctcatt cattaattag tctacatctt cctcccattc ttcatagatg
     7021 gctgcatctt tttcataagg caagacaata gtaaaggtcg atcctttacc atagtcactc
     7081 ttagcccaga taaagccatg gtgctgcttg atgatttctt tagcaatggc aaggcctaga
     7141 ccggtccctc cttgggcacg acttcttgcc ttgtctacac gatagaaccg atcaaaaata
     7201 agaggcaaat ctgttttagg gatacctagt ccttggtctg aaatggaaat aattaattgg
     7261 gtatctgttg ttttcatacg gactgtaatt tttccaccat ctggagaata cttaatggca
     7321 ttgttcaaaa tattctcgat aacctgtgtc attttatcat tatcaatttc aatccagaca
     7381 gaggtaatag ggtaatctct tacaatttca tagacttttc ctgtacctgt atgctgattt
     7441 ttaaccaaat caaatctgtt taaaatagaa gttataaaag cagtaaaatt agtcatctct
     7501 actgctaatt gggttacttg attatcaatc cgagacaggt ttaaaagatc tgaaatcata
     7561 cgcatcatcc gattagtttc atcaagagaa acttttatga aacttggagc aatatcttct
     7621 ttaagtgcac cttcatcaag agcctccaag taggatttaa ccgaagttaa aggggtcctt
     7681 aattcatgac ttacattaga gacaaaaaga cggcgttcac gttcttcttt ttcctgttct
     7741 gtggtgtcat ggagcaccac aaccaagccc gaaataaaac cactctctct cctattcaac
     7801 gcaaagcgca agcgtaatga gacaaactca cccatatcat ttcggctatt aacagttacc
     7861 actggtgttt tggataccaa atcacggtag gtatatgaag tatcaccttc taacaaatct
     7921 gtaatgtttt tctttagtgc ctcttcttta cttaaattta attgcttgcg agctgtctcg
     7981 ttaatcatga tgattttacc agaccggtct gtagcaagta caccatctga catataagcc
     8041 aaaatacttg ccaagcgatt tttttcttgg gcaagatttt catgcgtcaa gcgaaaaaca
     8101 tctgacaggt catttaactg gtctgaaagc tccattaact caatgtctgc tttttcgtcg
     8161 attatatcag tatagcgacc attaatcaag tctcggattt tatggctcat catccgaata
     8221 atacgtgcat ttcggtaatc acgcaccgca agatggataa agtaaaaagc aacaaaaaca
     8281 agtaagataa ggatcgctaa ttcaaatgtg gataagtttc caatgatatc tctagtcata
     8341 agatttcatg tagtacccaa caccacgtct tgttaaaata tactcaggac gacttggtgt
     8401 gtcttcaatt ttttcacgga ggcgacgaac agtcacatca accgtgcgca catcgccaaa
     8461 ataatcatat ccccaaacaa tttccaataa gtgttctcgt gtcatcacct gccccatatg
     8521 gttagctaga tgatgcaata gttcaaattc acgatgggtc aactctacct cttgaccatg
     8581 ttttttagca acaaacgcat ctggtaaaat ctgtaaatta ccaatggtca gttcctgtgt
     8641 acctgaagaa gcattttctt ctgcaacagc cgtttcaata gtttcggtac gacgcagatg
     8701 agccttgaca cgcgccagca attcccgatt agaaaagggc ttggtcacgt aatcatcagc
     8761 cccaatttca agtccaataa ccttgtcaaa ctcactatct ttagccgaca acataataat
     8821 cgggacatga ctggttttac gaatttcctt ggctacttca agaccgtcca actcagggag
     8881 catcaaatca agaataatta aatctggctt ttcttcttca aaaattgtta ccgcttcgcg
     8941 tccatcaaaa gctgtaacaa tgtcataacc ttcttttgtc aaattaaact taataatgtc
     9001 agaaatcggt ttttcatcat ccacaataag tatttttttc atgtctatac ctcagaaagt
     9061 tcttgtaatt gatattacaa tttgtgattt ttgtggttaa taaaaaatca caaaactata
     9121 tttttctaaa ttatttctac ctgattatac caaaaattca gcctaattga caatgacgac
     9181 taccgttaca aatagagtac tttctaaaac caacccttta taggatgaat ttgacgtttg
     9241 aattgcttag ctgatttttt gactctggca aaactactct tgttgtggta agcaaaaagt
     9301 cctttggcat taaaataaga gaacataaag tcatcttttt gagctctaaa ccactggcga
     9361 aatactcttt ttggcgatcg aaatccttta agggtgtctc ttctaaactg aggatcgtga
     9421 tggctaatcg gatcaacatc taaatcccaa tgtctaggac catctgtgcc atagttaaaa
     9481 gatgcaccat tgacaattcc tttttcggtc actacttctg catcaacttc attaagaaaa
     9541 aagcctgtgc tatctagagt aaattcggta tgaaaccaaa gaagtacttt tatattatag
     9601 gaaacttctt gacttggaaa aatgacttta ttatcttcaa atcttagttt attatgtaac
     9661 ctggcagaat ccatcaaggt ataatctggt gcttgccgcc acaaacaagg ccctttttta
     9721 gacctcaaaa aaagggccag agcttgggcg tctgtcatct caatcatttt ataatggttt
     9781 ctgatagatt gagcttgttg actagagatg acataacgaa attgatgcaa acgcttttca
     9841 agctcacctg cttggcttag tgttttgcca ggaaaagctt gatcaactaa gctagccaac
     9901 tctttccaaa acatatgatc tggcaataga gatggatgga atcgggtgag tagcgtttga
     9961 gtttcatgca actgaccact tagctcaaat ggcatctcta ccaaatcaag aagaaacgtt
    10021 agtaactgct tagctgattg gttttctttt tcaataggcc atattaccca gaaagttgga
    10081 gaaccaagtc gattatcaat gataggctct ttagctatag cacgaaatgc ttggtttgat
    10141 aaacctgcgt tttgatagca tttcaaggcc tgatagcgat ctaagatagc ttgtttcatg
    10201 gccttctcct catctttttt gaccatatta taacacatct aaagctgaat cgtcacttgt
    10261 atctcactat aagcaaaacg aaacctgaag tggttaacta agccactgtt tgggtatttt
    10321 atttaaaaga acttctcgat taattttacc attatctttt aaaggcaaac aatcaatcac
    10381 aagatagtac ttgggaagtt gtccagagtt taaataaaga gctaaaaagt ctttaatagg
    10441 tgctaggcaa tccttcttag tcaaaactaa tactaatatt agggtttcgt tttctccttt
    10501 tcctatcttt aaagcgtgcg cttctttgac gtttggcgct tggtgagcga gttcaactag
    10561 gctaggcagg tggcatttca ctcctcgttg attaacccag tcatcttgtc gcccttctaa
    10621 aattaaaccc gctgggctca tttttcctaa gtctgaaaca ctgtatggtt gtgacattcc
    10681 ttctacacta taaggagtct ctacaaaaat ttccttatct ttgaaactga tagacacatc
    10741 aggaaagggc tgtcctacca aaccattaat tttgacagca gctctgccat tacaccacgt
    10801 tataaaagat aattcactag ccccgtagaa aatgacaatt tcaagctgag gaaatttttt
    10861 gtaataatgt cttagtaatt cttgtgatat catttgcgaa gaggtcaata agtgagtcgc
    10921 agtcatgttg ttcttagtca aataaggtag caagcgattt aggtaggtcg gtaaaaggta
    10981 aaggtgactc accttttttg cttgccataa gcttaaccac gttttcaaag acagcttttg
    11041 gcttaaaacc agacatcccc cggcccatag ttgagctaat gctaagttaa gattgccagt
    11101 aaaactaaaa ctaccatgta agaatagaca actattacca gtcataccaa acaccttatt
    11161 ttgataatca aaaagtctcg tccaagttga tagacgacgc caaaataatt ttgctttgcc
    11221 agttgttccc gaactcaaaa cagcaaaatc agctttttta agaagctcac catcgacgtg
    11281 ttttatttgc tgctgaaatg tacctgagat attagggtgt aaaatgatag gacaactgcc
    11341 ttcttttaat cctcgtaaaa aagagagtaa ctgattaaga tagcgactat gactgatgat
    11401 atatggtaca ctgtctttta ttgtctgatc ctttattaaa accgcttgcc atagctcttg
    11461 ataagtcaag cttatctgat cggctacgat agctttttta tttgggcatt gctttgccca
    11521 atattctagc tttgtcagca tgactaaact ccttatgata ttttagtaaa acagcaaacc
    11581 cttggccacc agctgctgct atagcagcta ttccatagcg tccattttta atctctaaag
    11641 ccctcattaa gtgcaatatt ataatggctg ctgaggcacc atagggatga ccataagcta
    11701 atgcaccacc aaatatatta tagcggtcca ataaatctgg ataatgggtt tcaaatagac
    11761 catcaataac ggcaaaggct tcgttccatt caatcgctgt catatctgcc atccctagac
    11821 catgtttttc caaaaggact tgactagcct taatcaccat taaagggcta cgctgtgggt
    11881 ctcctgctac ttctaccaca tcaatcagtt taaaagctga aggctgacta cttagctgta
    11941 aaaaggcagc agcatcatgg gttaggcagg cattggctgc actaatcacg tgaccttctc
    12001 ctaagatagg gggtaccttt gacaacacct tacttgacaa gcgcggtcga ataccttgat
    12061 cactggctcc tgacaggtct agaataagat cagctaacag ggcttgctcc tggcaataac
    12121 tagccttttg atgacttctc aatgtccagt gattcaaata ctcctttgta aagccatgct
    12181 ctcttgccac tcgttctgcc ccttcaatca tcgcaaaagg gctgatacta tctggagaaa
    12241 actgagctac cttgtaggct ccttggcgcc aatcagctga agcatatacc gattcaggtt
    12301 gtaaggagct gctttcaatc cctcccacta aaaggttgct tgccatacct gccttgattt
    12361 tagcataacc cacggaaaga gctgcaccag ctgatgcaca ctgcatatca accgtcaaag
    12421 cagagacaga ttctcctaaa tgagaataca gggtcatcaa gcgcccaata ttaccacccg
    12481 ttccgacggt attgccacaa atcacttggt caatgggaac tggatactta ttttgtaaag
    12541 cgttgatgag ctttgctcca aggatttctg gttgttcttt agcaaattgt ttccctacta
    12601 aaccgatagg ggttctaagg cctgcagcaa tataaacatc cgtcattata ttgacctcct
    12661 ttattttcga tgtccttaaa tggttattgt ataattattt ctgatggttt tcttttttga
    12721 actaataact gctaaaaata cacctaaatt aatttagaga atctctttag tctcgctagt
    12781 gtgctatcaa taaaatctat aaaattctct aacgtcattg aaatgtcaag tcccacaact
    12841 attgtcgtag aagtcactta ctttgttgct ttaacattca aactgtaacc tttgtttttg
    12901 atacagggtg actttattat actggaaaac cattcctaag aaaagaaaat cttatataga
    12961 ataaagaatt agacaccata aaaaagctaa gctgtgacac ttaacttttt tatggtattg
    13021 acaaaccttg tctttactat ttattgatag ttaatgcctc taactaaaat aaaagccatg
    13081 tctgtaccag cctgcaaggc atctgctaag ctggtatcgt tactagattt ggcaggtctc
    13141 ataaaggcaa aagatctcaa agttccataa acgttatcta gcaattgcat gcaaccactt
    13201 gaaacatatc tgcttatgtt attttaccgc ccttaattta gaccaatctg ctgatgatgg
    13261 ttccaaccaa tgcctacgct tggtaaacca tcacaaaaaa aggcagccgt ttttacaaca
    13321 gctgccttcc ttcattatct aggttttcat attctgacct aaacgatttt caatttgttt
    13381 aagagtctct ctaggaatct gcactttcat aagcatccag gccccatttc caaagcttaa
    13441 gcgacaaggc caaaaccagt aacgacacca ctaccaagcc tccaatatta aagagcaggt
    13501 gttgacctgt taaaaaataa gaagcagggt aataagctgt aaaagcaaag ggaatgataa
    13561 aactgattaa ccaccgcaaa aaggaatggt aaatggacat agggtactta gaaaagtcat
    13621 tgaacatgta aaaaatatag ataactgccc cagactgctt ggtccaaaaa gaaatgctgg
    13681 cggtcgcaat ttttaaagag gtgtaaatca aggtcgcaaa aggaataacc aaaataaaca
    13741 aaagcacctt aggaagagtc catacgatac taccagccgt ggtcactaat aagataaccc
    13801 caaccaataa ttcacccagg gcatccactt gaaaggtctc aactaaaaca tgaaacaaag
    13861 gactaattgg tctggtgagg tacttgtcaa attctccttt gcggacaagc cgttgcccta
    13921 aagcccaaag attgtcaaaa aagaggtgat caattccctt tggaatcaaa caaaagccat
    13981 aaataaaggc aatttgttca aacgtccagc cttctaaaga agggatatgt tggaaaagta
    14041 ccgataaaaa gagcagatta agtccctgag tgagaaaaac acctagcact cccaccacaa
    14101 aatcaacctt gtattccata atttgtttga ggtattgttt gataaaaata gcgtgcatac
    14161 atctcaattt tgccatctca ccctccttga atcgttaaat ggtactgaac ctttttccag
    14221 atgacttgcg ataagactac catcaccagt aaccaaaaga tttgcaaact tagggccacc
    14281 attatctgac taaggctgta tttcccaatg acaatcataa ctggcgtgta aaccaaagag
    14341 gaaaacggta gaaaactaag cactatagaa accattttag gaaaaaaagc caatggaatc
    14401 aaactgcctg acataaaggc aaccaaggca tttttcaata aattagaccc ccaaaggttt
    14461 ttaaagacaa atgctgaaga gccaaaacaa atgttgaaat aaaaattgat taaaaaagct
    14521 aataaaaggc taactaaata cagacaactg ctggctagga cttgcaagat agacagcccc
    14581 gccatgactt taataccaga taagaccatt aaaaaaggaa agccgacact cattagcaca
    14641 atccagcgaa aaccaatttc cataaagagg taagaggctg caaaatgaac tggtcgaagc
    14701 aggcgcatga tgatagaacc atctttcact tcttcgccaa tcataaagga gctgtctgat
    14761 ttggtcagta aagtggtcac aaaactcatg ataatgtaaa aggtcatgtc agacagagta
    14821 aaaccattga ttaaggattg cttagacgaa tcaaaaacag ccttccagag gtaataagcc
    14881 acaaaagccc ccatgacatc tccaatacga tacaaaaaga aattaacgcg ataggttatt
    14941 aattcctgaa ttcctgcact gagaaagggt ctataacgtt tccaaaatga ccacatctta
    15001 aagctccttt cggtagaaac gacgaacaat atcctcaata tctacatcag tcatcttcac
    15061 atccctgacc gcaaaatcag ccatggtttt ttgaataatg tccgcagttt gatagcgcga
    15121 actgtcatat tgaatgtcta aactaaactc atgccgttcc actgtgatgt caggtaagcc
    15181 cataaactgt gagaccacct gctcctgccc tggcttcaac tcaaaagaca gactcttcat
    15241 ttttccaaag ctttgcttta attgggtcac cgttccatca aagatttctt gccctttatc
    15301 aatcatgata atccgatcac agagctgttc aatatcactc aaatcatggg tcgtcagtaa
    15361 aatagttgtc tcttcttctt gattaatttg agtaatggca cgccgaatgt tgtccttcac
    15421 agaaacatca agtccaatcg ttggttcatc taaaaacaat actttaggat tatgcaacaa
    15481 ggaggcagca atatcagctc gcatccgctg accgagtgat aaggtccgga caggatcctt
    15541 aataaactca ttcaggtcca aaacctcatt taaaaaatcc atgcgcttgc gaaaggcttt
    15601 ttcaggtaca tcgtaaattt cttttaaaac gacataggtc tcttgcaagg ccaaatccca
    15661 ccatagttgt gttcgttgac caaaaacagc tccaatgtct ctcacataat attgacgatt
    15721 atcttgtgga atctttccgt taatgcgaca gtaacctgat gtaggcttta aaatacctgt
    15781 taacatctta atcgttgttg attttcctgc accattggcg ccaataaaac ctaaaatttg
    15841 ccctttgggt acctcaaaag ataagtcctt aaccgcctca aagatttctc tttggggatg
    15901 aacaaacgac ttcaaggctc cctttaatcc tggctcttta atggttttgg aaaaattttt
    15961 ttgaaggtgg gacacttcta tcatgaccat ttaccattcc tcgtttctgt tatcgtctta
    16021 tcaccgttac taaacaattt attataacac cataaaaaag acggtgcaac cgtttgctta
    16081 attttttaag aaagaaaaag aagcccataa ggacctcttt ttgccattga ttaagcttgt
    16141 gcatctggac gtgacttgcg agcaatgtct gccaagatgt tttccacaaa ttcttccaca
    16201 gattcggtgt gagtcgtctt gctaccatag cggcgaacat tgactgattt gtcttccatt
    16261 tctttgtccc caacaattaa ttggtaagga attttgctgg tttgagacgc acgaatcttg
    16321 tactgcattt tttcattgcg gtcatcgaca tctgcacgaa caccacggtc acgaagggtt
    16381 tttgctactt cccaagcata gtcaatgtgg gcttcatttg aaattggaat cacggttact
    16441 tggtgaggtg ccaaccaagt tgggaaagca cccttgtaag tttcaataag gatagcagtg
    16501 aaacgttcca tagttgagat aacaccacgg tgaatcatga ctgggcggtg ttcttcgcca
    16561 tcagcaccaa tgtatttgag atcaaagcgt tctggcaaca agaagtccaa ctgaatggtt
    16621 gatagggttt cttcgttacc aagagctgtt ttcacctgaa tatcaagctt aggcccataa
    16681 aaagctgctt caccttctgc ttcaaagtaa tctacaccca tctcatcaag tgcagcttta
    16741 agcatacttt gagcattttc ccacatctca tcattgtcat aatatttatg agtatcgtta
    16801 gggtctcggt atgacaaacg aaaacgataa tcagtcaagt tgaagtcagc ataaacatca
    16861 atgattaatt gaagggcacg ttgaaattct tcctggattt gctctggtgt tacgaaaatg
    16921 tgaccatcat tcaaggtcat ttcacgtacc cgttgaagtc ctgatagggc acctgatttt
    16981 tcgtaacggt gcatcatgcc aagctcggca atacgaatag gcaattcacg ataagaacgc
    17041 acatgatttt tatacacttg aatgtggtgt gggcagttca ttggacgaag aacaaactcc
    17101 tcaccatctc ccatatccat tacagggaac atatcttctt gataatgatc ccaatgacct
    17161 gatgtcttgt acaattctac agaagcaagt ggtggtgtgt aaacgtgttg gtagcctgat
    17221 gctaattctt tatctgtgat gtagcgctca agtgtacgac gaatagtcgc tccatctggt
    17281 aaccaaaatg gcaagccttg gccaacttct tggctaatca tgaacaagtc aagctcttta
    17341 ccaagcttac ggtgatcacg ttctttagct tcttctagac gagtcaagta agctttgagg
    17401 tcttttttat caaaccaagc tgttccatag atacgttgca tcatgttatt gtcgctgtta
    17461 ccacgccagt aagcacccgc cacattgagc aagtggaaga cttggatacg gcctgttgat
    17521 ggcacatgag ggccacggca aagatccaca aattcacctt gacggtaaac cgtcaagcca
    17581 gcaccagcat gctcattaat caattctacc ttgtaaggat catctttgaa caattccaaa
    17641 gcttcttctt tggtcacttc ttcacggata catgggtaat tttctgtcac gattttttgc
    17701 atttcagctt cgatacgtgg caaatcttcg tttgaaattt ggccttcagc attatctgta
    17761 tcatagtaaa agccttctgc aatggcaggg cccacaccca aatgaagatt tgggaacaag
    17821 cgttttgcag cttgggcaaa taaatgggct gcagagtggc gaagcacctc ataagcatct
    17881 ttgtggtcag gtgtcacgat ttcaatactg ccatcttctt caatggcacg agtggtgtca
    17941 atgagttgat cattgaactt accagctaaa gcttttttag ccaatgattt gctgatggac
    18001 tcagcaatgt caaacgttgt tacgccagat tcaaattcac gcacggcgcc atctggaaaa
    18061 gtaatcttaa tcatttgctt tctcctttaa gtcagttaag atttccacta aaacatggat
    18121 agtaagacaa attagggaca agaggttagt gaatagctca ataccaccac gtagaagaac
    18181 aataccttat tcacgaatct accctcccta gtccttaaaa acaaggctaa tcccctccaa
    18241 aacaaaaaaa ctgaccgcat cccaaaggac gcaatcagcg tggttccacc ttaatttatg
    18301 caggacaaaa aacatgcctt gcacctctag tggcgataag ggggccaccc ttttatgttt
    18361 gcataaaaac caggaaggag tatcagatta gctatccttg tgctctttcc accaaccagc
    18421 actcgcttaa aagattctgt ccaatctaac ttgtcttcaa gataattata gcaagttttc
    18481 aaaaatttac aagtcttaat ccagaaaatc tttgatagca tggaccagct tgataggagc
    18541 cttgactact tttactgagg tgatagctgt gaccttagca gcacgtttag gcaagtgaat
    18601 agcaccttgc actaatttta gagaactact tttaccagaa tgattaagat aaagactcag
    18661 cttttgagct tctttgctat ttctagcaat taacgtatct aaatagaacg tgtaaataga
    18721 ttttccaaag tgctgtgctg agatttcata acgttttttt gctaataacc gtttatccat
    18781 aactggtgtt tttagtatgg catcaataat agcatcagtt aaatctgttt cagcgtaata
    18841 aagagtgcca aacattttat cagtcaccac atcatctaaa taaggattgc catgagcaat
    18901 aataggagtg ccactagcca aactttcaat ataggtcaag ccctgagtct cactagttga
    18961 tgctgagata aagaaatcac aagccttata gtacagagca accttatcat gaggcaccat
    19021 gcctgtaaag gtcacgtgtt tgtcaacctc taactgcatc gccaagtgtt tcaaatcttg
    19081 caaatagggg ccatttccta caataataag ctttatcttg gcattttcag ccaaaatagc
    19141 tggcatctga ttgatgatag cttgaatatt tttttcataa gaaatccgtg acaaactcaa
    19201 taacatggtt tcatcaccag caatgcccaa ttctgctttt aagttggtta cttcttctgc
    19261 tgtgatgtca tcacgaatat atttttccaa aggaatgcct gttgggataa cccgcttagg
    19321 gatagtaact tcgtaacctt ctagaagatt gaggacaatc ctacttgggc agataacccc
    19381 atccaaatcc ttcaaatagc ccctaagaag aggtttgacc atacttggtc gaatgatttt
    19441 tccgttggca atataactca cgtagtcctc atattgggta tggtaagtat ggacaacagg
    19501 aattcgcaaa gctttgccta tcattttccc taataagcct aagctaaact cagtttgcgt
    19561 atgaataata tcaagattat agtgttttgc aattttgtat gacgaaatga ggccacgata
    19621 aaccacacgt ctatccgtaa atgacacaaa aggaacactt ggcagtcgaa taatggtcgg
    19681 gtcttcaaag cgtttgacat ctctatcagt agtggtgaaa atataaactt cgtgaccttc
    19741 tttttctagc tcttctttta acgtacgaat actagtagcg actcctgaaa cttgtggaaa
    19801 ataggtatct gtgaatagac ctatacgcat cttataactc cattactttt ttatagacat
    19861 ctactaaggc atggccaacc gtttctaggc gacgactctg ggcaaccttg taaccagctt
    19921 caactttgtt gctggcacca gaaaagactt ttttcagagc ttctataaaa cctggtatat
    19981 cggttgctaa ttccgcacta ctttgatcaa cccatccgta gtaaactggt atatcacgta
    20041 aaacaaggtg ctggcgactg gccaaggctt ctaagacaac aatgccttct gtttcttcac
    20101 gacttggaaa gaaaaaggca tctgcaccag tcatggcacc ttcataaaca tcccctttaa
    20161 tgtatcctgg gaaaataaga tttttcgggt ggttaccatt gaccatttgg cgaacttgag
    20221 caggaatgac ccatttgttg gtctcgccaa accagataaa acgaacatct ggcatagctt
    20281 gggcaacttt gacaaagtca tcaattcctt tcctcagaaa aaataatcct gctcccataa
    20341 ccactttttc accctcttta atgtcaaagt agcgacgaaa agctgcttcc tttttaggat
    20401 ctgctccgta ctgctccaaa tcaatcccat ttgacactgc aaaaataggt gacttcactc
    20461 cataactctc aatcaaagac ttagaatata gggtaggggt aatgatagca tctgccttat
    20521 tgtaaaagtg acaaaggtat tttttaaacc aaggagataa tagatttgaa aaaataaaag
    20581 aatttctaaa atcttcttct gtagaatgcc catgcatgat aaccttctta ccagcttttt
    20641 gtgcttttat catcagcagc caacttttta aaccataggt attgagatga accaaatcat
    20701 aagtttctct tggattagtc gtaaaatgtt gaccaacaag tgacaaggct ttagcctgat
    20761 gcttaatcgc tcgaccaatt cctgattttc ttagataatt ttctgcttct aaatacaata
    20821 agactttcat aagttctatt atagctcatt ttatagtatt tttcactaag acatgcaaaa
    20881 atcagcccta aggctgattt tagtattgaa gaaacagtct attgtgatac tttttgttag
    20941 atggtgctca taattcacag ttacttagtt gtcccacgtt ttttaatacc atgattcaaa
    21001 agaatttctt tttcttccaa ctcttctttg ttcatgattt tagtcaacat ccgcatgcta
    21061 acagcaccta agtcataaac aggttgactg atagaactca aattgggacg agtgtattga
    21121 accactggtg aatcgttgct ggtgatgatt tcaaagtcct ctggtacgcg tttacctgct
    21181 tcaaacaagc cgtttaaaag gcccgctgcc aattcatctt cagccacata agccgctgtt
    21241 gctcctgagt taatgacgcg ctgcgccaat tcaaatcctt ctttataaga atagttcgct
    21301 tcaaaaacaa ggccttcttt gaagtcaagc ttattgtgct tcaacccttc tttgtaacct
    21361 gctaagcgca ctttaccatt gatatcatca atgagtggtc ctgacacaaa agcgatacac
    21421 ttatgatttt cagctaaaat atcaacaacg tttgacaccg cagctctata gtcaatgttg
    21481 acgcttggta attgatgatc aagatctaca gttcctgcca aaacaactgg agtacgagag
    21541 cgtgaaaact cggcccggat tttttctgtc aagtgatgcc ccataaaaat aataccatcc
    21601 acttgcttgg caaaaagggt attgacaaca ttaacctcct tgtcatcatc ttcatcactg
    21661 gaggcaagca caatattata tttgtacata gcggcgatat cgtcaatacc cttagctaag
    21721 atagaaaaat aactatttgc aatatttgga atcacaacgc caacggttgt tgtctttttg
    21781 ctggcgagac cacgcgcgac agcattggga cgatagtcaa ggcgatcaat aacttctaaa
    21841 actttcttac gtgtattttc cttaacattt ttattgccat taacaacacg actaacggtt
    21901 gccattgaaa caccagcttc acgggcaaca tcataaattg taatggtatc atctgtattc
    21961 attttttatc ttcctttcta tttgaaaatg acgctttcaa aaagtatttt agcatgattt
    22021 gtaaccactt tcaagtgtta taggttaatt tttgaaaaag ttttcaaaaa ttaactcgaa
    22081 gcttgatttt ttaagctttt tttgaaaaaa tagtaagtag aaagaaggtt agcctatgac
    22141 aaaattagac caaatacgtt tgtatcttga ccaaaaggga gctgaattgg cgattttctc
    22201 agatcctgtt acgattaact atttaactgg attcttctgt gacccacatg aaagacaact
    22261 gttcttgttt gtctaccatg atttagctcc tgtgcttttt gtacctgccc ttgaggtggc
    22321 cagagctagc caggccatat catttcctgt gtttggttat gttgactctg aaaatccttg
    22381 ggaaaagatc aaggccgttt taccaaatac agcagccaaa accatttatg ctgaatttga
    22441 ccaccttaac gtcaataagt tccatggctt gcagactatc ttttcaggac aatttaacaa
    22501 tctaacccct tatgtccaag gcatgcgcct cgtcaaatca gctgatgaaa tcaataaaat
    22561 gatgattgcc gggcagttcg ctgataaggc tgttcaagtt ggttttgaca atatttcctt
    22621 agatgctacc gaaacagacg tcatcgctca aattgagttt gaaatgaaaa aacaaggcat
    22681 tcataaaatg agctttgaca ctatggtctt aactggaaat aatgcagcca atccccatgg
    22741 cattcctgga acaaataaca ttgaaaacaa tgccctactt ctctttgact taggtgttga
    22801 gaccttaggc tacaccagtg atatgaccag aactgtggct gttggtcagc cagaccaatt
    22861 taaaatcgat atctacaatc tctgcctaga ggcacaacta gcggctattg actttatcaa
    22921 accaggtgta acagctgctc aagtagatgc tgctgctcgt caagtgattg aaaaggctgg
    22981 atatggtgag tacttcaacc accgcttggg acatggtatc ggcatggatg tccacgaatt
    23041 tccctccatt atggctggca atgacttggt ccttgaagaa ggtatgtgct tctctgttga
    23101 acctggtatt tacattccag gaaaggtcgg tgtgcgcatc gaagactgtg gccatgtcac
    23161 taaaaatggc tttgaagtct ttacccatac tccaaaagag ttgctttatt ttgaaggcta
    23221 agcctctacc atctggttaa acaaaccctc gcgaaaggaa ggtattcgta tggatcaaac
    23281 cattcatcac caaatacagc aagcactaca ctttagaaca gccgttcgtg tttataagga
    23341 agaaaagatt tctgatgagg atttagccct tatccttgat gctgcttggt taagcccttc
    23401 ttctattggc ttagaaggct ggcgctttgt cgttttagac aacaagccta ttaaagaaga
    23461 aatcaagccc tttgcctggg gagcccagta tcaactggaa acagctagtc actttattct
    23521 tttaatagcc gaaaaacatg caagatacga tagccctgct atcaaaaata gccttttacg
    23581 gcgtggtatc aaagaaggtg atggtctcaa cagccgccta aaactctatg aatctttcca
    23641 aaaagaggac atggatatgg cagataatcc tcgggcactc tttgattgga cagctaaaca
    23701 aacctatatc gctcttggta atatgatgat gacagctgct cttttgggca ttgatacttg
    23761 ccctattgaa ggctttcatt atgataaggt caatcatatc ctagctaagc ataatgtgat
    23821 tgatttagaa aaagaaggca ttgctagcat gttatcccta ggctatcgtt tgcgagatcc
    23881 caaacatgct caagttcgta agcctaaaga agaagtgatt tcagtcgtta aataaggaga
    23941 ttaaaatgaa agcattacat acctgtatcc gcgtcaaaga ccttgaccag tcggttgctt
    24001 tttacacaag tgccttccct tttaaggaaa actatcgtaa agattttcca gatagtcaat
    24061 ttactcttgt ttatctggct ttagaaggag aaagttatga attagaatta acctacaatt
    24121 atggtcatgg cgactacgac ttaggaaatg gctatggtca tattgccctt ggctctgaac
    24181 attttgaagc agaccataaa aaacatcgac aagcaggttt tccagttacc gatatcaaag
    24241 aactggctga caaatctgcc cgctattatt tcattcagga tccagatggc tacaaaattg
    24301 aagtcattga tttaaacaac taatactatt aacaacagaa gctttaaagc ttctgttgtt
    24361 ttatttttta acctgacgat tgggacaatc tcattattaa cagagttttg aaatatctca
    24421 gcttttgtgt tacaattgcc ctaaaattcc atttgaaaga aaagtctatg acactactat
    24481 ctatcattgt cccctgcttt aatgaagaag caaacattct cccttatttt gaagaaatgc
    24541 atcaactaga aacgtccatg accaaccaac ttgcttttga atacattttt attgatgatg
    24601 gttctaagga taacaccttg ggtattttgc gtgagctagc tgctcgcttt ccaaatgtgc
    24661 attatctgtc tttttcacgc cattttggca aggaagctgg gctcttagct ggactaaaag
    24721 aagccaaagg caattacatt actgtgatgg atgtggatct gcaagatcca cccgaacttt
    24781 tgccaattat gtacgctaag ctaaaagaag gttatgacat cgttggcacc aggcgccaaa
    24841 atagacaagg agaaccacta attcgttcaa tgtgttcgaa tctattttat ggactgatca
    24901 aacacttatc agatactgaa atggtcaatg gagttcggga ttatcggtta atgaccagac
    24961 aagtcgttga tagcattctt gagttgggag aggttaatcg tttttcaaaa gggatctttt
    25021 cgtgggttgg ttatcgtatc acctatctta gttttgaaaa ccaaaaacgc aaatatggaa
    25081 aaagtcgttg gcatttttgg gagttgctcc gatattcttt agatggcttt atcaactttt
    25141 cagaaatgcc gttaaccatt gctacctgga cagggacttt cagctttttg atttctattt
    25201 tcgccatctt atttatcatt atcagaaaga tactctttgg tgatcctgtc tctggttggg
    25261 ccagcactgt ctctattatt ttattcatgg gaggcattca gctcttttgc atgggtatta
    25321 ttggaaaata tatttcaaaa atattccttg aaactaaaaa aaggcctctc tatattatca
    25381 aagaaaaaca ttaaattaaa acatttttct catcaatcgt ttcctactcc ttctgtgcgc
    25441 gaagctttct ttttaagccc gttataccaa atgataatga cctttccaaa atagtatcac
    25501 cctccttaac actttaagta gaaaaggaac tattaggttg agcctttttg caaatcctag
    25561 cgactaatgt tataatcgtc atactattga aaaaggagtt ctttatggag tggattaaat
    25621 taatcggtat tgtgattatc gtattagggt ttattttaaa atgtgatgct atcgctaccg
    25681 tagttgttgc aggacttgtt accgcgctgg tttcaggaat ttcgtttatt gattttctag
    25741 atattttagg aaaagaattt accaatcaac gtttgctaac cattttcttc atcactttac
    25801 cgcttatcgg cttgtcagaa acttatgggc tgaaacaccg agctactcag ttgattcaac
    25861 gtgttcaagc ccttaccgtc ggccgtttat tgactctcta ccttattatt cgagaattag
    25921 caggtctctt ttcgattcga ctagggggac atccacagtt cgttcgaccc ttgattcaac
    25981 ctatgggaga agctgctgct aaagccaaca ttggagaaga gttgaccgat gcagaaaaag
    26041 atgacatcaa agctatggca gctgccaatg aaaactttgg caatttcttt gcccaaaata
    26101 cctttgttgg cgcaggaggt gtcctactta tcgctggaac tttagaacag cttggctatg
    26161 atggtaacca agctaaaatt gcattttctt ctattttaat tgctattatc tctattatta
    26221 tagttgctat ttacaattac ctctttgaga aaaaaatgga acgtcaacat cagaaaggag
    26281 ataactaatg gctaacattg caaaccttgt tttagaaacg atatatatcc ttatcggctt
    26341 gcaactgttt cacacagcct actgcacctt taaagataaa accaaccctg tctattttgg
    26401 gacagctctg ttctggggat tgctgggtgt taccttcgtt ggcggtgcct ttttgcctaa
    26461 taaagttatc ggttttatcg tgattgtcct agctctttta accttgttta agcaagttcg
    26521 tattggaaca ttaccagcct ttaatgaaca aaaagctgaa gaaagtgctc accgcattgg
    26581 taactggatt ttcttaccag ttatgttaat ggctatgatt tctctacttc ttgccttgat
    26641 ccttcctgat ttcagtaaaa gtgccattgg gattgctggt atcttagcca ctattgctat
    26701 tttaataatc actaagcaaa aaccatctgc tcttttagct gaaaataatc ggatgaacca
    26761 acaagtgtcc acaagcggta ttttgccaca gctcttagga gctttaggag ctatttttgc
    26821 agctgctggt gttggtgatg tgattgcttc tctcattcgg gagattgtac ctgctgatag
    26881 ccgcttcttt ggcgttctcg cttatgtgct tggcatggtt atttttacta tgattatggg
    26941 aaacgctttt gctgccttta ccgttattac aaccggtatc ggtgttcctt ttgtttttgc
    27001 tttaggagct gaccctatta ttgccggtgc tttagctatg actgctggtt tttgtggtac
    27061 cttattaaca ccaatggcag caaactttaa tgccttgcct gttgctttga tggagatcaa
    27121 agatcgaaat gcagttatca aaaagcaagc tcctatcgcc cttgttttaa ttattagtca
    27181 cattgcctta atgtatttac ttgcttatta ttaacttttt tgctaagtta gtagcgtcag
    27241 ttattcattg aaaggacatt attatgaaaa ttcttgtaac aggctttgat ccctttggcg
    27301 gcgaagctat taatcctgcc cttgaagcta tcaagaaatt gccagcaacc attcatggag
    27361 cagaaatcaa atgtattgaa gttccaacgg tttttcaaaa atctgccgat gtgctccagc
    27421 agcatatcga aagctttcaa cctgatgcag tcctttgtat tgggcaagct ggtggccgga
    27481 ctggactaac gccagaacgc gttgccatta atcaagacga tgctcgcatt cctgataacg
    27541 aagggaatca gcctattgat acacctattc gtgcagatgg taaagcagct tatttttcaa
    27601 ccttgccaat caaagcgatg gttgctgcca ttcatcaggc tggacttcct gcttctgttt
    27661 ctaatacagc tggtaccttt gtttgcaatc atttgatgta tcaagccctt tacttagtgg
    27721 ataaatattg tccaaatgcc aaagctgggt ttatgcatat tccctttatg atggaacagg
    27781 ttgttgataa acctaataca gctgccatga acctcgatga tattacaaga ggaattgagg
    27841 ctgctatttt tgccattgtc gatttcaaag atcgttccga tttaaaacgt gtagggggcg
    27901 ctactcactg actgtgacgc tactaaacct attttaaaaa aacagagata tgaactaact
    27961 ctgttttttt gtgctaaaaa tgaaagacct agggaaactt ttcatcggtc tttctcaatt
    28021 gtcatcttaa tctaatacta cttctaacat cagcgggtat agtttgccag taattaagaa
    28081 acgttgttga tctaaatgag caatcccatt caaaacatta aggtcagggt aatgggactt
    28141 atcaagattt aaggctttta acaaaggact aatatcatag gtggctacca cctttccaga
    28201 atcaggttgg agtttgacaa tagtattggt ttgccaaata ttggcataga gataaccatc
    28261 tacatactct aattcgttaa gcattgagat ggggacactt tctatagcaa ctagtacggt
    28321 atccaataaa gcaaaatctt tggggtctcg cttttgcaaa aaagcatttc cactagtcat
    28381 ccaaagacac tggttttcct tatcataggc taatccccag ccatctcctt caaatggata
    28441 ggcccctaaa caattgcagg tagccttatc aaacttgtag gctacaccct ctttataggt
    28501 tagtaaccaa aaataatcct caacaactgt tagcccttct gcaaaaactg tatctggaaa
    28561 agctattttt tctgaaaaga tctcttgagt aaggtcatac acccctactt ttgagaaacc
    28621 ataacgaccg gcactaagta atatatgatt gttgttgagt tgttctaatc cctgcgtgta
    28681 taagttgcta tcataagaat aagttcgtaa caaacgaact tgtcctttag ttatcataat
    28741 actcattcac cttaccttgc attgtagtgt ttcatttgtt ttttaatatc tctttcctga
    28801 tcacggcgtt taatggtttc gcgtttgtca tactcgtgtt tccctttagc tagaccaatc
    28861 agaactttag caaagccatc cttgaggtaa actttgagag gaactaaggt catgccagat
    28921 cctttaagtt catttgctag atgcgtaatc tcacgttttt tgagcagcag tttgcgggtt
    28981 cgttcaggat cagcgttcca aatattacct tgttcaaaag gtgcaatatg cacgttgacc
    29041 aaccacgctt ccccattctt aatttgggca aagccatctt tcagttgaat acgagctgca
    29101 cgaacacttt taatctcagt tcccgttaag acaatccctg cttcaacggt ttcaacaatg
    29161 tgataatcat gtctagcctt tttattttgc gccagtatat gaccttcacc ttttgccata
    29221 gttaactcct tttacgactc ttcttttttg cttgttcttt gtaaaatggt tttttagacc
    29281 cttttttagt tttacccttg gtttttgcct tggctacttc tttaggttct tttttctttg
    29341 tccctttaga tgattttgag gatttacggc gatctcgtcg actagcttta tccgacatct
    29401 tgattttttc aaccacatca aagtcgctag gtaaatactc aaagtcaatg tcaccagttt
    29461 ccttgtcagc cttaaccaat ttcacacgaa taggttgacc gaccttaaag accttacctg
    29521 atttttcacc ttgaaggctt agcgttcttt cattaaagtg atagtattcc ggtaagctag
    29581 tgatatgaac caaaccttca atcgtatttg gcaattctac aaaaaaacca aatttaacga
    29641 cactggaaac gataccgtca aattcttcgc cgacatactc tgccatatac tcagcttttt
    29701 tcatggcttc aaccacgcgt tcagcatcaa tagcacgacg ctctaactgt gaagaagatg
    29761 ttgctaattc tggaatgatc tgagcaaaat ggtcgcgctt ttcttgacta ggttgattgt
    29821 actcacgaac catgcggtga accaataagt cagggtaacg acgaatcgga ctggtaaagt
    29881 gagtgtaata ttctgcggcc aaaccgtaat ggccatgatt atgttcagaa tacctcgctt
    29941 gttgcatgga acgtagaagc atcatgttga gcacttctgc tcctggttga ccttcgactt
    30001 ttgccataaa ggcttgcaag gcttcctgag aaatcttgtt ggctgttcct tgaatgtgaa
    30061 taccaaaggt gctagcgtaa tcaataaatt gttgaagttt ttcggccttt ggttcttcgt
    30121 gaatacggta gataaacggt aacttagctt ttgcaaaatg ctccgcaaca cactcattgg
    30181 ctgctagcat aaaggattca atcatccgct ccgcaatgcc cctttgacga agcaccacat
    30241 caaccggcat tcctttgtca ttaacaataa tttttgcttc ttgcgtatca aaattcaagg
    30301 cgcctcgttt tgaccgcata gcttccaaaa tcctatgcaa agccaccatg agggtcacat
    30361 catcagcaat gctagcgaat tcttggagcg cttcttcatc tcctgcaatc atgtcattga
    30421 ccgtactata cgtcattcgg taagttgtct taatcactga ttgacagatt tgataattga
    30481 ccacatgccc ttgagaatta atttccatca aggctgactg ggtcaaacga tcaatgttag
    30541 ggttcaaaga gcagatgcca tttgacaaac gctctggtaa catcggaacc acacgatcgg
    30601 tgacatagac agaagtgcca cgggcgatag cttccttatc aagggcagat ccttctgtca
    30661 cataatatga gacatccgca atatgtaccc caagttcata attcccgtta tccaatagct
    30721 taatatggat agcatcatct aagtctttgg cgtccgcacc atcaatagta atggtggttt
    30781 cttgacgcaa atccacacgg cctattaaat ctttagcagt tggtgcttct gaaatagcat
    30841 tggcctcagc taaaacttct gctggaaatt ctgacacgat atccatcgat tcaaggactt
    30901 ctaggacatc aattccaacg tctccttgat ggcctacgat atcacgcaca ctggctacaa
    30961 aataatcgtg cccgcgtatc gggtatttat caatatcaac cttgatgatt tcagtgcctt
    31021 taagcacaac aggttctttt ttgatataga ttttttgttg aatcttttgg tttttggacc
    31081 tgatataacc agcatatttt ggtttgtcat catctaaaat aaaggttcca acagctgttt
    31141 ttaaagaacg gtcaacaata gcaacgacct tagcttcagc cgctgtgcct ttgagacggt
    31201 ctgctggctt tttaaccact acttcgacag tatcaccatc aatagcatac ccaacatcat
    31261 tacgaccgat aaacatgtca tcttcattct catccacatg taagaaacca aagcctgctt
    31321 tattggcacg aaaaacaccc tgaacagtag gttctttttt cttttcacgc tcttttctaa
    31381 gagccagact gccatcatct gaaaaccgta acaggctctg actttccatt ttggaaatgg
    31441 ttttaataag gctgggaaaa tgcttagctc cagccatctc caaggccgca gccaagtcgt
    31501 tcacattgga cttgccatgc tccttgaggt aagtcataat tctttctttc atcataccta
    31561 atttctattt ctgttttgtt tgttggagga tatcaatccg tttcgctgat aaaaaaatga
    31621 gctagactaa ctctgtcaag ctcactcctt atttacttga taaaatggca agcacaagtg
    31681 caatcgctag ccaaaaaaat actagaactg ctgtgaatcg ttgcatgaat gcttcaaagc
    31741 cacgagcttt tgtacgttca aacaaggctt ctgaaccgct gctatcaaaa acattgctac
    31801 ttgggttttt ttgaggttgc ataaaaatag caatcacaag caataccgac agtactagca
    31861 atatcgtaag tagtaagttg tacatgttat ttcctccact attgtcatga ccattctaac
    31921 acaattctta tcaagtttca acatgcaggg tcacttttct ctccttgggg cagtatttgg
    31981 gaacttttat tttttccgga tgactgcttt tatttttact ggttagataa ttgttactgc
    32041 cacactcact acattctaaa ttaattttta ctctcacaca atatccttaa ctttaatata
    32101 ttttcgaaat ataatcaaac tccatattaa attaacaaac acaatcaaac tagtcacata
    32161 aaaaacagaa cggtagccta acactacagc cacatttgat ccaataaaag ggccaatgac
    32221 ttgaccaagg ttactaaaca tttgattata ggcaaatact ctagaaatac cttcttttgg
    32281 tgttaactta gttagtaaag agttaatact tggcatcaaa gcgcccacac caaacccata
    32341 agcaaagcgt agtactccta attgaaaact ggtctgcgct aaggcactgc taaaatacat
    32401 gataaagcta taacacaaag cggctaacaa taaccgatga ttgccaaatc gatctcctaa
    32461 ttttcctaag taagaactgc taaataagct agaaaacccc atggccgaaa ctaccaggcc
    32521 tgaagtaaac attaagttgt gagtttgacc aagatgacga atatacaatg ataaaatggg
    32581 ggccactgat tgagctgaaa tttgaataat catactagtc acaaataaac caagcataat
    32641 ctggggactt tttacctgtt ttaaaatgac ttttgtaggt atcatctcaa agcgcctaac
    32701 cggcttaaac tcttctttaa cataaacagc tgtcattaaa gaacataaaa ataatatcac
    32761 accaactaat aagaaaactt gtcgaattcc taatagctct gccaaaattc cccctagtaa
    32821 aggaccaatt aaagcgcctg ctgtcactcc tgttgctaat gtgcctaaag cataacctga
    32881 ctcctctttt ggggcttggc tggcaatcaa ggcagtggca tttggcacat agcccgcaaa
    32941 gacacctgtt aataatctca aaatgagtaa ccaaaacaca ttaggaataa tagctaaacc
    33001 acccattgta aatgtcataa caaaactggc tcgcagcatc ataggttttc ggccataacg
    33061 atcagccaac ttcccccaaa caggagcaaa taaagctgaa gcaagtgccg tcacagcaac
    33121 tgccagacca gcatagtatt ctactaattc tgtcggagta cctaaatttt ccacatatag
    33181 agccataaaa ggcataacaa gtgaaaagct tgccccagta aagaagttac caagccaagc
    33241 cacttttaga ttttgtcgcc agttcactgt cgttaccgct ttatcactaa tagatcatca
    33301 tcttctttcc attgggcctt tgattattat aacacatttc tgccaaaaac agtgtcccat
    33361 aatagtgcta agtctcatct gatagccttc atcgtttacg taaactaccc agtaaacctc
    33421 tgaccagttc tcgcccaatt gttctaaccg tcgtactaat aaacgcatct gttgcttttt
    33481 cgacgactgt tttgtgggaa cgcccaacag aacgccgatt agcttttttg gtagctgctt
    33541 gcgccttgat ggcttcttta gcttcttttt cgcgttgtgc tgtcgctatc gcttcttggg
    33601 ccagtcggtt gtcttctaaa accttagcag ctaatttttc ataagcagat tcacggtcaa
    33661 tggactgact atatttactg gcaaaaggtg aggactgcac aagctgctga ctctctatct
    33721 ctgacaaaac agcaaagcta ctcttaggcg gcatgatata ggcacgttca acgatggatg
    33781 gttgtccctt atcattcaaa acagaaatca aggcctcacc gacttctagt tctgtaatca
    33841 cccttgccac atctaagtca ggattttgtc ggaaagtatc cgcagcgaca cgaaccgcct
    33901 tttgttcttt cggtgtataa gcgcgaaagg catgctgaat acgatttcca agctgagcca
    33961 aaaccgtttc tggcaaatca agtgggtttt gagtcacaaa gaaaatccca actccctttg
    34021 aacgaataag tcgcacaatc tgttcaactt tttccaagaa aactttaggg gcatctttga
    34081 agagcaagtg agcttcatca aaaaagaaaa ccatcttagg tttgtccaaa tccccaactt
    34141 ctggcaataa tttgtacagc tctgataata accaaagtaa gaaggttgtg taaagggtag
    34201 gagattgaaa aagcttagtc gctgacaaaa tgttaatggc tccataaccc gaagcaacat
    34261 ctaattgcat caaatcagcc acatctaaag caggctctcc aaaaaattgg tgggcccctt
    34321 cttgttccaa agtcaagaga cttctttgga tagccccgat agattgctta gcgatattac
    34381 cgtaatggct ggagtagtct gaggcatggt caccaacttc ttttaagata gcctgcaagt
    34441 ctttcaaatc aatcaaaagc caacctttct cgtcggcgat tttaaagacg atgtttaaga
    34501 cacctgtctg ggtatcatta agattcaata aacgcgacaa catcataggt cccagctcag
    34561 aaatcgttgt ccgtaagggt tgaccgtttt gaccaaaaac atcccacatt cttacaggaa
    34621 aggcctgagg ctggtaatca cttaccccga ttatggctaa acgcgcagcc aatttatcag
    34681 tcacctctcc tgctttagta agattagaca ggtctccttt gatatctgcc aaaaagactg
    34741 gcacaccagc taaacttaat tgctctgcta gcacttttaa ggtcacagtt ttacctgttc
    34801 cagtcgctcc agcaatcaaa ccgtgacgat ttagcatccc taattgtaag gctatcggtt
    34861 gattgccttt tgcaattgtc attgtagtca taggcttcct cttttttgat gatcatactt
    34921 atcgatatgt gtttacccat aagttaaagt gtttagaagg gtctcactct taatactatt
    34981 ataacatata acccttgatg cgctaattta aaagggacca gctagtttta gacagaaata
    35041 gcttgatttt gacagctatg atacgaatct ctcagcttag ctacctcgga ttggctaata
    35101 acaacaacgc agattgtact tgctttatta aggctgcaat atccccacta ttatcaatca
    35161 ctagactggc atagggcttt ttttcctcta ttggtaactg actggctatt cgctgccttg
    35221 cttttccttt gtctaaacga tttctagcca ttaagcgctg caattgtgtc tgagcatcta
    35281 cataaaccag ccaaatcgca tcaaaccagt cttggtagcc caattccatt aaaaggggaa
    35341 tatccatgaa aaaaatggct tggctctgtg ctaagtggtc acgcttagcc gccaattctt
    35401 ccttaatgat ttgattttga atggctgagg atgttgccat attatctggg tttgaaaaaa
    35461 gcatttctga cagctttgtg cgatctaact caccatctgc ttttaaaatc tgattcccaa
    35521 aagcttctct aagagcctcg taaagacgac cgcctttttc ttgcaagtca tgaaccactt
    35581 gatccgcatc aatcacctga taaccagctt ttctaatgac cttaaccaca gtcgattttc
    35641 ctgatgcaat gcctcctgtg atgccaataa tcatagtctt tttttctggc attttggaca
    35701 aatgtgcgtc ccccttcctc caacttttaa tttgacaata gcctgtccac aacgaggaca
    35761 cggtttccca gtttgaccat aaacctgcaa atagtcctgc atggtgccat cagctcccaa
    35821 agcattacgg taagtacgga cggtcgaacc gcccttttca attcctaaag ctaggattcg
    35881 tatggtttca tcatgcagcc gttttatctc cgccttattc aacctagaag acgcagtttc
    35941 tggatgaacc ttagcagccc aaagtacctc gtccacataa atattcccta aaccagcaac
    36001 caaggtctgg tctaaaagat gtggttttat gggtttttgg gaggatagca gagcagcctc
    36061 aaaggttttt aacttaaagg tctctttctt tggttcaggg cctagttttc gtttggcaaa
    36121 aaacgctgat aattgagatt ttgctatcaa atcaaaggtt ccaaatttac gcacatcttg
    36181 gtaaaccaag gtcgaaccat ttttcaattc aaaaaagaca tgaaagtgtt tgttatcagg
    36241 gacctcatct ggaaaaagca aatatttgcc ttccatccgc aaatgtgata ccaacactaa
    36301 ttgccccaaa tcaattaata aatattttcc ccgacggcca actgactgaa tgatttgacc
    36361 aggtagggtc agggcaaacg tctctaagtc ggttttaacc atttttggca ctttaagcgt
    36421 aacagccaca atttcttggc caagcactaa agtctcaagt cctcgtcgga ccgtttcaac
    36481 ttctggtaat tctggcataa tccgttattt aaaggacagc tagacccttt gctcctacaa
    36541 agaataaact cagtataaaa aagtcactca atagactcag gtctaggcta ctgactgcgt
    36601 ttcaaaaaac acagctgtcc ttctcctttc ttatttctta ttttacgaac acatctgata
    36661 gaaagcaact cataaatctg cctcagacca gtcctcatcc cccttacctc ccagcactat
    36721 ttgacggtaa tgttccttat aactataata caatgagtcc tctccaagat acttaaaaat
    36781 ctgcaaggcc tgccgcatgt cctcttctcc agacatttct tcctgcttta atttataata
    36841 cccatgcaca tataagaaaa cagtcttttc ataaaaattg agctcgtctc gcagcaaaag
    36901 atcaattttg ttaatcaaat agcgactatg ttcaaagcaa gaatggtcaa tactgataat
    36961 gagacaatta atggataact gagtcactaa cattttattg gttttatttt gttccgaata
    37021 agcaaaagat gctaccattt ccttagtcaa taaaaatagg gtattgtaat tcatgaagcg
    37081 cgagcaattc cccagaagaa tgatttcata atatccccac tgttccactt taaataaata
    37141 atctgtgagg cgagtcaatt cttcttgact aggtgcaatt gaggagtcaa tagaaaaaag
    37201 aatagcttta atcatcgttc gttcataatc tttatgggca taatccttca acagtttggt
    37261 caatttaacc acgtttttct cagcataaca ttttctcgcc tgacttaaga gcgtgaaaaa
    37321 atgcgtatgc gtcttggaat gagccgaaac aaattcgtca atcgtaatat tcagtttatc
    37381 caaaagatta agcaagcgac tgcaggtgat ttctgattcc cctcgttcaa atcttgaaat
    37441 ttgtgacttg gacaggtatt catctgctaa aaaagaaatg ctaacctgct tacccttacg
    37501 taatcgcctt aaggtttttc cgagttcttt ttccattttt cccactttca caacaaaaaa
    37561 ttaaaatctg ctaaatccat tatataatac aagtacaaaa tagaaaatca gaaaggagac
    37621 agtcatgaaa aaagttaata aagctttgct ttttacattg atcatggata tcctgattat
    37681 cgttggtgga taacctttcg cttaaaaaca atccactttt gggaaaccct tatatttagt
    37741 ttgtaacagg aaaactaata aatattaaaa agagtgttag cgacctagcg gcagctttac
    37801 tcttaagtgc gtttgctgcc attgacagca aggtcaaggc tgatgaaaca gcaggggcat
    37861 accgttatga tgtgtctgga caaaacactt actatcaaac tatcagctcc attaaccagc
    37921 aacgacctgg tgccactctc gacgaatgag gtgattatta tggaaccctt acttcattta
    37981 cttcccaaag tcgtaccagt acttatacac ttggtagaca aagccaacgt atcatggtta
    38041 acagtgatat tacagttacc tatactctta aagacaattt ggtagccctt cataaggaat
    38101 ataaaacctt tgtcaaaaaa atattacaga taaaccgatc accagtgact acgacaaggc
    38161 taaggttatt tataaccatt taatcaacga atacacttac gccacaaaat aacttagcac
    38221 caattgcaaa accgtaagca gcatcaacaa tcatactcct aaagctcttt atcgtgacaa
    38281 gtgtggtgtt tgtcaagctt atgccgtcat gtttaaagat atggcagaag ctgcaggctt
    38341 atcagcttgg tatgtgataa aaaaggattg aatgagcacc atgcttgaaa catcgttacc
    38401 attcatggtg ttaattccta cgttgatgct acctggaatg attcagcata caccacaagg
    38461 tatttccttg ctggaaaaga cgtgaggaat actgagtacc gtttagatag ccagtacaac
    38521 cacttggcta atgctatttt aaataccagc taccaaaaag gctaaactaa caacaactac
    38581 atttttcaaa tagaaaggcc taaacaatga ccaaaaaaca gttttatctt atcttagcta
    38641 ttagcatact gtgttttatt cttgccgtca gccctaaacc accaattctt aaacacacta
    38701 ttgaaaggaa aaggactgcg atgaccatag gccactcaaa acaaaaccct cacaaaaaag
    38761 aagcccttaa acacaaaaaa aacaaaaata aggctctttt tcttccaagt ggggacagcg
    38821 ctatcaaatc tgttattagc atgacagtta gactcctgtt agatgaccaa tcttagctct
    38881 cctaaaatca gtggacacta ccatttcggt agtgttcttt tttaagctaa tctcatcacc
    38941 acgctttctt caagctaaaa aactgatcat gaaagagcaa ccccatcacc ctaacagccc
    39001 actttgcccg cactttctta aaaagttagg agaaaacgat ataccaatta ttttctgatc
    39061 ccagctccct atcattaaca agatgtgtag cacggaccta catacaggta agctagagtc
    39121 attctcgcta tttcggacaa aaagaggccg gtagttccct gacctcttct ttatttatct
    39181 tgtaacactc ctcttcttag cgagacttac tagcacataa ttcttaagca ctcttatcat
    39241 ttagactagg aataacacca tctgaatgaa gcaaatgatg cgtcagatct gccagagtat
    39301 catctccata agtaatccct gtttggtgct gtttctgatg aaaatcagat gactccttaa
    39361 ctttagcagt cacctgctgg tcacttggat gaaaattaat ttctctcttg gcttcagccg
    39421 caactggctc gaggaacaac ttattgacat cacggtcttc ctccaaatga ttaaggatag
    39481 cagcatcatc ttctaacgaa agaaccttct tgggtaacaa aaaggggtta tttagccttg
    39541 gctcagtaac gacttccttg gctactcgtg atagtttatt attgtcttcc tcaggtatca
    39601 aacggttagg caatcgatgc aattcttccg gctgtgaggc gctcacagct acttcagaag
    39661 aaacctccaa gccctttcct gtttgcctgt ctaaagcaac cggcaaatta ttaactaact
    39721 ttttaacctg tcctcagcgc tcatttcaac actaggaaga gctgtcgctg gttctagcca
    39781 gctaccaact tctgctggtc ttaccttaac atcgctggca ggcttctcct tctcatcttc
    39841 attaggtcta aaaggctcaa accgccctgt tgatttttca tctatgacct ttatattgtc
    39901 ttttactaca tgagacagtg gttcgacatt taccatagct tcatgctcgt taaggctctg
    39961 gtctcgtttg aatttaccag gaataccagg agtcggtgtt ccgacagatt gatcggcttc
    40021 agtaggctct tttacggagc cttttttcca taaaactgct ggaggaataa tatccgtaga
    40081 gccgtcccca taagtaatcg tggcctgcct cccctttgga ttaatagata ctttaatatt
    40141 gtctgggaaa gccccactac ctcctgtggt taaaagggca cccgcatttt taatgagagt
    40201 tgtcattcgt tcaataccag caacgccaat atggttcaag tcatctactg gtaactgatc
    40261 aacagatttc atggtgtatt tccaagcttg cggttgaaca agaaaaacag ttcctttata
    40321 cattgtgtta tgcatatcat caatgacttt gaaatacctt atatatttgg tttgtacatt
    40381 agggttagca acgggaacag tgctttcagg aactcctgac atcgtaaaaa tccctctagc
    40441 agaagtttga aagccctcat aaacatgacc cataccagga acaatctgag cggtcaaaga
    40501 cttatcagaa ccatccaaag caatgcgaat atctttcatc agagacatct gattggtata
    40561 ggcaaaccta accgtgttag cctcacctcg atacaaaacc acttgggagg gctgatccga
    40621 agaaaactga gaggttgttt cttccttata gccaactcca aaagccaact ccaaaacgtc
    40681 tatcagacga atggactgaa tctgccgcaa ctgtactact caaactgact agtaaagtag
    40741 ccgcacaacc aactaataaa ctgctcgttt taactttaac atctcttaac atcatcatgt
    40801 tcctttcatt attttttatt taggaattcg acatactata ttttctcata ttagtctaac
    40861 aaaaaactcg taattctata taaatcatat aaaatgacga gctttggcaa agatgagtat
    40921 agcaggatgg aaaacagatt atttctgaaa cttcaaaggt atcttcttgt cacgaactat
    40981 tctttaattg aatcggttac actaaactag tcccattatt taaaaacaaa ctttaaatat
    41041 tattcatttc actt
//
LOCUS       DAUGJR010000014        40688 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUGJR010000014 DAUGJR010000000
VERSION     DAUGJR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40688
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.014"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            56..1252
                     /locus_tag="VH800_000725"
     CDS             56..1252
                     /locus_tag="VH800_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8361804.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            1754..2602
                     /locus_tag="VH800_000726"
     CDS             1754..2602
                     /locus_tag="VH800_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8361805.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(2938..3834)
                     /locus_tag="VH800_000727"
     CDS             complement(2938..3834)
                     /locus_tag="VH800_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEQ8361806.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            4132..4884
                     /locus_tag="VH800_000728"
     CDS             4132..4884
                     /locus_tag="VH800_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEQ8361807.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            4869..5819
                     /locus_tag="VH800_000729"
     CDS             4869..5819
                     /locus_tag="VH800_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEQ8361808.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADATVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(5997..8324)
                     /gene="pflB"
                     /locus_tag="VH800_000730"
     CDS             complement(5997..8324)
                     /gene="pflB"
                     /locus_tag="VH800_000730"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEQ8361809.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            8533..9627
                     /gene="dinB"
                     /locus_tag="VH800_000731"
     CDS             8533..9627
                     /gene="dinB"
                     /locus_tag="VH800_000731"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEQ8361810.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVKKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNVKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(9720..10202)
                     /locus_tag="VH800_000732"
     CDS             complement(9720..10202)
                     /locus_tag="VH800_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361811.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(10293..12746)
                     /locus_tag="VH800_000733"
     CDS             complement(10293..12746)
                     /locus_tag="VH800_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEQ8361812.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFALQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(12804..13397)
                     /gene="lepB"
                     /locus_tag="VH800_000734"
     CDS             complement(12804..13397)
                     /gene="lepB"
                     /locus_tag="VH800_000734"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8361813.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(13408..14310)
                     /locus_tag="VH800_000735"
     CDS             complement(13408..14310)
                     /locus_tag="VH800_000735"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEQ8361814.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            14467..14775
                     /locus_tag="VH800_000736"
     CDS             14467..14775
                     /locus_tag="VH800_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361815.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            14778..15323
                     /locus_tag="VH800_000737"
     CDS             14778..15323
                     /locus_tag="VH800_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEQ8361816.1"
                     /translation="MLSLLIVLILTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLNYFDNQWTKCLSGGLAFLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLTRL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            15472..17811
                     /locus_tag="VH800_000738"
     CDS             15472..17811
                     /locus_tag="VH800_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEQ8361817.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSTDLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADGSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG"
     gene            17815..18315
                     /locus_tag="VH800_000739"
     CDS             17815..18315
                     /locus_tag="VH800_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8361818.1"
                     /translation="MESYEHFYAKLSQPFRKTPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSALLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            18396..18710
                     /gene="trxA"
                     /locus_tag="VH800_000740"
     CDS             18396..18710
                     /gene="trxA"
                     /locus_tag="VH800_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEQ8361819.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(18762..19349)
                     /locus_tag="VH800_000741"
     CDS             complement(18762..19349)
                     /locus_tag="VH800_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361820.1"
                     /translation="MEIGQQIIRYRKQQALSQEKLAEKVYVSRQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSNGKLLDEIEKREE
                     RATLPYQKPLIVTVFFLITVAFAFASRFMFTWLFH"
     gene            complement(19425..20549)
                     /gene="mutY"
                     /locus_tag="VH800_000742"
     CDS             complement(19425..20549)
                     /gene="mutY"
                     /locus_tag="VH800_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEQ8361821.1"
                     /translation="MWDNETIASFRRTLLEWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            20747..21040
                     /locus_tag="VH800_000743"
     CDS             20747..21040
                     /locus_tag="VH800_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361822.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKINLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            21213..21503
                     /locus_tag="VH800_000744"
     CDS             21213..21503
                     /locus_tag="VH800_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEQ8361823.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            21525..22016
                     /locus_tag="VH800_000745"
     CDS             21525..22016
                     /locus_tag="VH800_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8361824.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            22181..22420
                     /locus_tag="VH800_000746"
     CDS             22181..22420
                     /locus_tag="VH800_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEQ8361825.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(22553..23209)
                     /locus_tag="VH800_000747"
     CDS             complement(22553..23209)
                     /locus_tag="VH800_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEQ8361826.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQKAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(23342..24286)
                     /locus_tag="VH800_000748"
     CDS             complement(23342..24286)
                     /locus_tag="VH800_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEQ8361827.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            24489..27317
                     /gene="uvrA"
                     /locus_tag="VH800_000749"
     CDS             24489..27317
                     /gene="uvrA"
                     /locus_tag="VH800_000749"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEQ8361828.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEITASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKGKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGDGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            27432..28505
                     /locus_tag="VH800_000750"
     CDS             27432..28505
                     /locus_tag="VH800_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8361829.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDASEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYLSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSRFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            28540..29001
                     /locus_tag="VH800_000751"
     CDS             28540..29001
                     /locus_tag="VH800_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEQ8361830.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            29097..29654
                     /gene="efp"
                     /locus_tag="VH800_000752"
     CDS             29097..29654
                     /gene="efp"
                     /locus_tag="VH800_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEQ8361831.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            29700..30089
                     /locus_tag="VH800_000753"
     CDS             29700..30089
                     /locus_tag="VH800_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8361832.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            30082..30534
                     /gene="nusB"
                     /locus_tag="VH800_000754"
     CDS             30082..30534
                     /gene="nusB"
                     /locus_tag="VH800_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEQ8361833.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSGAPSANKS"
     gene            complement(30675..31640)
                     /locus_tag="VH800_000755"
     CDS             complement(30675..31640)
                     /locus_tag="VH800_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8361834.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(31645..33084)
                     /locus_tag="VH800_000756"
     CDS             complement(31645..33084)
                     /locus_tag="VH800_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEQ8361835.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTHGQTGIQVVEGQAFGHYYEMRY"
     gene            33326..35209
                     /locus_tag="VH800_000757"
     CDS             33326..35209
                     /locus_tag="VH800_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8361836.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKHGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLSAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            35440..38427
                     /locus_tag="VH800_000758"
     CDS             35440..38427
                     /locus_tag="VH800_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8361837.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KGLPSIDSLHYLSENSKKEFKEELSKAGQESQKVKEILAKAQQADKQAQELAKMKIPE
                     KIPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLF
                     WKELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDVEHDSIPKVDKKEDTAGVERSIQVFEEIGKLIGPKGVDKSRLF
                     IMDSTYMADKNPLIERGAPYINLLLVQVYGSQGEKGGWEPVSNRPEKTMEERWQGYSK
                     YIRPEQYMIGFSFYEENAQEGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKT
                     GGVKGGIFSYAIDRDGVAHQPKKYAKQKEFKDATDNIFHSDYSVSKALKTVMLKDKSY
                     DLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNKFKKLAQLD
                     LIGLSRITKLDRSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLKVSGLTGLK
                     ELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLSTISNHVGS
                     NEQTVKFDKQKPTGHYPDTYGKTSLRLPVANEKVDLQSQLLFGTVTNQGTLINSEADY
                     KAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATDKEETYKVD
                     FFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFDGQLGSETDN
                     ISLGWDSKQSIIFKLKEDGLIKHWRFFNDSARNPETTNKPIQEASLQIFNIKDYNLDN
                     LLENPNKFDDEKYWITVDTYSAQGERATAFSNTLNNITSKYWRVVFDTKGDRYSSPVV
                     PELQILGYPLPNADTIMKTVTTAKELSQQKDKFSQKMLDELKIKEMALETSLNSKIFD
                     VTAINANAGVLKDCIEKRQLLKK"
     gene            38691..39575
                     /locus_tag="VH800_000759"
     CDS             38691..39575
                     /locus_tag="VH800_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8361838.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIART
                     IAYFKAFEADLAGMAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTALLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            39670..40623
                     /gene="manA"
                     /locus_tag="VH800_000760"
     CDS             39670..40623
                     /gene="manA"
                     /locus_tag="VH800_000760"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEQ8361839.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
BASE COUNT        12325 a         7206 c         8627 g        12530 t
ORIGIN      
        1 tatattctgc tttttttgta aaatgtttat gaaaatagag aggagttcat tttcaatgga
       61 agaaaaattg tttaacaaac attttgtggc catcacagta ataaacttta tagtctatat
      121 ggtctactat ctttttacag ttattattgc ctttgtggcg actagagagc taggagctca
      181 gactagccag gcaggattgg caacagggat ttatattcta gggactttat tagcccgttt
      241 gatttttgga aagcagttgg aggtgtttgg tcgtcgtttg gttttaagag gaggtgctat
      301 tttttacctc ttaacgacct tagcctactt ttatatgcca acgattagca tgatgtactt
      361 ggttcgtttc ttgaacggat ttggttatgg tgtagtatca actgcgacaa ataccattgt
      421 aacagcctat attccagctc gtaaaagagg agaaggaatt aatttttatg gcttgtcaac
      481 cagtctagca gcagctattg gcccttttgt aggaaccttt atgttggata atcttcatat
      541 tgattttcgc atgattattg tcttatgtag cgtcttgatt gggtgtgtgg ttgttggtgc
      601 ttttgctttt ccagtcaaaa acatgtcttt aaatgcggag caattggcta aaaccaaatc
      661 gtggactgtg gatagtttca ttgagaaaaa agccttgttt atcactgcaa tcgccttttt
      721 aatggggatt gcctatgctt cagttttagg atttcaaaaa ttatacacgt ctgaaattca
      781 tttgacaaca gtaggcgctt atttctttgt ggtctatgcc ttaatcatta ccatcactcg
      841 tccagcaatg ggacgtttaa tggatgctaa aggcgataaa tgggtcttgt acccaagtta
      901 tcttttttta gcaatgggac tcttcttgct aggtagtgta tcgtctggag gaagctattt
      961 gctttcagga gccttgattg gctttggtta tggcactttt atgtcttgtg gtcaagccgc
     1021 ctccatacaa ggagtggatg agcaccgctt taatacggct atgtctactt atatgattgg
     1081 tcttgattta ggtttaggtg ctgggcctta cctcttgggc ttgattaaag atttggcact
     1141 tggtagtggt gtggcttcct ttaggcactt attctggtta gctgctgtga ttccactgat
     1201 ttgtaccttg ctttacttgt taaaaacaaa gacaagacag gttgtgtctt aaggacaaga
     1261 aaaggagttt agtcttatac ttaaatacaa acgtatctta acagctgtag atagttccta
     1321 tgagccggga ttagctgtgg gtaaagccat tactatagcg ctttgaaata atcctagttt
     1381 gctattggta catgtcaata aaaatgactc gcaaaagcca ttcgtgaaag agaaaatgtg
     1441 gccttatttt tagtaggtac aattggatta agcacgttta gatacatgac aattggatta
     1501 acatcagaat ataggctttg tcatgttaag attgatctgt tgatagtgag agctaataaa
     1561 aaatgttata atactatgaa ataaagtgat aaagataagg ccttttatgg tccttttctt
     1621 taccgctttt attattgtgt gaaaataaca cttaatgatc attttattta ttattttatt
     1681 acctttacat tcatcaataa gcctgttaaa atggtatttg ttatatttta ttatttggag
     1741 gaaaccagaa aacatggaaa tgacatggac tgtgaaatac atcacagaat ttatcgcaac
     1801 ggcttttttg attattttgg gaaatggagc tgttgctaac gtcgacttaa aaggaacaaa
     1861 aggacataac tcaggttggt tagtgattgc ttttggctat ggcttaggag ttatgatgcc
     1921 agctttgatg tttggtaatg tatctggaaa ccatattaat cctgctttca cagttggact
     1981 agcagtatca ggcttgttcc catgggctca cgtcttacaa tacgttgtgg cacaattact
     2041 tggagctatc tttggtcagt tggtagtggt aatggtttat aaaccttact ttatgaaaac
     2101 tgaaaatcca aatcatgttt taggctcatt ctcaacgatt tcatctcttg ataatggtca
     2161 aaaagacagt cataaagcct cttatatcaa tggtttctta aacgaatttg taggttcatt
     2221 tgttcttttc tttggtgctt tggctttgac taaaaactac tttggggtag agttagttgg
     2281 taaattgatt gaagcaggct acgaccaaac aactgcagca acacaaattt caccatacgt
     2341 gacaggctca ttggcggttg ctcacattgg tattggtttc ttagttatgg tcttggttac
     2401 ttcattaggt ggaccaactg ggccagcact aaacccagcg cgtgattttg ggcctcgttt
     2461 gttacaccac ttcttaccaa aatcagttct tggtcaagcc aaaggtgatt caaaatggtg
     2521 gtatgcatgg gttcctgtag ttgcacctat cttagcggcg atagtagccg tagcagcgtt
     2581 taaatacctt tatatcagat aaaaaaagaa ctaaagcttc ttttagactc aagacaagct
     2641 cgcttaagga acttgtcttt tttatatgag ttaagcgaaa tctaatacaa acttgactgt
     2701 cttgtatagc gtattttgta aattttatta gacttcttgt aaaaagcctc tcctcagata
     2761 agatgactaa tgcctctaaa cggtgttaca aataaacgag gcatctctaa cttcctttat
     2821 ctggtgttga aactattttg cacggactaa atcactgata gagtcaaaaa acaatttttc
     2881 atttttgttg taaaatatta aaaacgtctc tggttagtga ttcccagaaa cgttatctta
     2941 tctatttgtt tgttgcttat gagaggtaaa ggaggaacga atcagcattc caccagtgaa
     3001 gaaaacgata gcgatgacca gaagtttcaa gctattaata tctaaattcg ttaagaaaaa
     3061 cacagctagt aaaacgccaa taataccacc agaaacaatt ccagcaaaac catcccaact
     3121 gacacggttt gctttgataa actggctact agaagctgtc ataatcatag ctgcatctag
     3181 catcataaca ggcatagcaa ctgttgggct aagacccatt aatgaaaaga aaatcaattc
     3241 tggagcataa ttgcctaacc ccatagtcat caagactcca acgataaaat taaaaccaat
     3301 tccaacaaaa agccagatgc catggaggcc atgaatggtg tctgaaaggt gttctcctgg
     3361 atggtagatt attctaatga tcatgattat agctgctatg attaaaagac taccaaggat
     3421 tcgttggaca gttggagcat gccagttttt tgtaatatga gtcccaaaat aagctccaat
     3481 aaaggctgct gcagccatag caagtaaagt tagaacctca acttttacga caaaaataaa
     3541 gcaaagagat tgaatgagca ccggaagcac atgagctacg gtcatagtgc caggcaattg
     3601 tctatcgtca gtgactaatt tagttaactt aaagcacgtt gtggtagtag caaaagaccc
     3661 tatcccaagg gtgtcaaggg catctgttag caggccaatc caaaaccccg tccaaaagcg
     3721 tttaaaagga ttgatcttat tttttttaag atgttttact aacataaaga aaataaaaag
     3781 cattgccgaa actagcaaag cttgtatcag tctaaggata agcatttcgt tcataaagac
     3841 tagtttacaa aaaaaaacct tagccgtcaa cgtgatttac ttcattaaaa catgccacta
     3901 tgcttagaag agctttagtt cgatgtattt tgttaaaatt aagctaaaat attaatattg
     3961 catgaaaggg gacgccttcc tttttccctt actgagctta gctgttattg tagtgaatgt
     4021 ttaaaaggct agtttgtcgc tctttatcaa aaatctagta ggatgaatac gtataatttc
     4081 ttgtcaaata gaggaatttt gtctataata gcagaggatt aggaggaaat tatgacttta
     4141 atggaaaata ttacctttaa aactccagta ttacgcgtta atgatcgcga ccttaatatt
     4201 gcattttatc aaaataattt agggcttcgt ttagtatctg aagaaaatgc gattgctatc
     4261 ttttcatctt ggggagaagg gcaggaatgt tttgtaattg aagagtcacc ttcagttaga
     4321 acgcgtgcgg tagaaggccc taaaaaggtt aatacgattg tcatcaaaac aaatcaacct
     4381 aaagaaatcg aacaattatt agctcatgga gcacattatg acgctctttt taaaggtcaa
     4441 aatggctatg cctttgagac tatttcccca gaaggagacc gattcttgtt gcatgctgaa
     4501 caagatatta aacatctcca aggtactgat ttaccatcgc ttgaaaaaga tgcgactttt
     4561 aaaggtttaa ctcaatttaa gtttgatatt attgttttaa atgttattag tgaagaacgc
     4621 tcaaaagctt tttatcggga tctgtttagt gatcagttac ctattactat ggattttatt
     4681 caagaagaag gtcccgattt ggcaattgat ccccatattg cttgggattt agaaatttta
     4741 gaatttcaag tctcaaagga ctatgatatg aaggtcctaa aagcaacttt agaagaagac
     4801 gggcacaagg tctacattga taaaaaacac aaagtattgg tcctttctga tccaagtcag
     4861 atcgaagtat ggtttacgaa atgactttgg cggtcattaa atgtattgaa aaccatcttc
     4921 acaaaaaagt atacaaaggg gccagtctgg ctctctttca atctggtcga tggcaagaat
     4981 accatatcgg aacaattgat ggaagacgac cagttgatgc taacttagtt tatgacttgg
     5041 ctagtgtttc aaaagttgtt ggtgtggcca caatatgcaa tattttattg aataatggta
     5101 cgttagcatt agatgatccc ttaaaggtat attatcctag tattgctgat gcgactgtca
     5161 ctattcgaca gttattgact cataccagtg gtcttgatcc ttatattcct aacagagatg
     5221 ttttaaatgc acaacaatta agaaaagcac ttaatcatct tactcaaaaa gaaaataaaa
     5281 acttttatta cacagatgtc aatttcctct tgttaggctt catgttagaa gagctcttta
     5341 gtgaatcttt agaccagata tttgacaaga ctatctttac tccctttggg atgtatcata
     5401 cgtcttttgg ccctcgtcca gaagctgtac caacattaaa gggtgtgagt gatggagaag
     5461 ttcatgatcc caaagcaaaa atcttaaaaa aacattctgg atctgcgggg ctattttcaa
     5521 ctcttgcaga tttagaaagt tttagcaatc attatcttaa tgatccattt tcagattgtc
     5581 tgtggcgcaa ctacagccaa caaacaattg agcggtcact agggtggaat ttagatggcg
     5641 attggattag tcatacaggt tacacagggc cgtttctaat gcttaataaa aaagagcaaa
     5701 cggcagctat ttttttgacc aaccgtactt acgacgagga tgataaaagt aaatggttaa
     5761 aagaacgtca gttgctttac aatgcactaa agcatgatct gacaaccccc gtatcgtaac
     5821 gtctaaaggg gcagttttag tgatcttatt actgttttta aagtttcttc taaaatagcc
     5881 atttcatttg tctgatgcga ttagagtgat tataagtgaa aaaagaatag ccatctcatt
     5941 ttgaatcaaa tgagatggct gttctttttt ataagttatt gatcatttag atactactat
     6001 ttacttgaaa tagcttcagc agcatcgtcc atggaaagca cttcgtggaa gacacgttgt
     6061 gtcaattcag ttttttgttc tggtgtaagg tatttggtgt tgacacagta accagagata
     6121 cgtacgataa cgtcttcgcc gttcatgatt ttgtcataaa catcgttaag gtccataacg
     6181 ttcaagttaa cgtgctgacc accattttca aagtaaccgt caagcactgt taccaagttg
     6241 tcaacttgtt cgtcaaatgt tttaccaaga gcacgaggtg atacttgagt agtcaatgag
     6301 ataccatcgt tagcatgtga gaattccagt ttagcaagtg agttaaggtt ttgtaaccag
     6361 ccaccttttg ctttgttaga tgggttagca cctggtgaga agaattccac ttggctagtg
     6421 ttaactgtac catcttcgtt taagaagacg ccgcggtgaa ctggagagtt accagtttgt
     6481 ttagagtaag caacgtttga agtgatggta agaagtgata ctgaagcctc agcattcttg
     6541 taaagtttgt ggcttgcaag acgtgtgtgg taagcttcca tcaaccattt cgcgatgtca
     6601 tcaacacggt cgtcatcttc accgtaacga gggaagtcac ctgttacttc gtagtcatag
     6661 atgtagccat tttcatcgcg gatagtttta acagttgcgt atttaatagc tgacaaggta
     6721 tcaactgtgt tagcgaaacc acagataccg aatcccatgt tagcacgttg gtgtgttggc
     6781 aagaaggcca tttgaactgc ttcgtagttg tatttatcag tcatgtagtg gatgatgtta
     6841 agcgcatcta cataagtatc tgtcaaccag tcaagagatt tctcaaagtt agccataact
     6901 tcgtcgtact caagaacttc tgatgtgatt ggttcaacaa cgttaaacac tttgtagtct
     6961 ctgtgaacat catcgtaacc accgttaaga ccagtaagaa gggctttaag aacgtttaca
     7021 cgagcaccga agtattggat gttatgacgt tgttcttcat tttctgggtc aagtggtgac
     7081 acacaacatg aaatacatga catttcacca taaccttctt tagccattgt tgtcacacct
     7141 tcatattgga tagaagagtg cttgtggctc attttcatac agtagcgacg gaatgtttct
     7201 ggcagttggt cagtccaaag aacagtcaag tttggttctg gagagttacc aatattatca
     7261 agcgtgttca agaaacggta gtccatctta gttacacggt gacgaccatc gttacccata
     7321 ccagccatag aagttgtgat gaatgttggg tcacctgagt aaagcgcatc gtaagctttc
     7381 gtacgaccaa attttacggt acggagttta aggacaaaat catcaacaaa ttcttggatt
     7441 tctgattctg taaaggtacc gcgagcaagg tcacgttctg caaagatatc aagaacgatt
     7501 ggcacacgtc caagagaagt agcagcaccg ttgatcacac gacatacagc catgaaagcg
     7561 atgtttaccc attggatagc ttctttaacg ttttgtgctg ggcgacgaac atcaactccg
     7621 taaaggtcac caagtttaac cacttcacca agagcttggt attgaaggtt aacttcttcg
     7681 cgaagacgaa tggattcttc atcgatttca gtgatagcat tccagtcatt gactttttct
     7741 tgcatcaagt agtcagcacc gtaaagagca agacgagcgt aaacaccgat gatacgtcca
     7801 cgtgagtaag catctggaag accagttaca gtgtgggcat gacgagcgcg acgaatattt
     7861 gaagtataag cgcggaagat accgtcgtta acagttgtca catacttagt aaagatttca
     7921 tgtactgctg ggtctggttc atagccgttt tctttaaggg tcgtttccgc catacggata
     7981 ccaccttttg gcatgaagtt caatttgaac aattcatcgt tttgaatacc ataaattaat
     8041 tcattttctt tatcgatgaa accagcagga atgtcagcaa ttgaagttgg acgagtatcg
     8101 tatgggaaac gtgtagcttc atagtgtgct tttgtttctt cgataacttt tttgatgtga
     8161 agtgaacgtt cagtagcacc agccaagaaa gattcatcgc catcgtatgg ggtgtagtta
     8221 gcttgtacaa aacgtgagac acttgctttt tctttccagt cagttccttt aaagccttcc
     8281 caagcttttt cgaaaacatc tgtattggtt ttaacagttg ccataaattt ctccttaaat
     8341 tctagtaaca aagcgatctg ttacatttac aattctaagt ttaacacata ggaaacgttt
     8401 tcccaagcaa aattcttgac aaaattaaga ttcttttata atacagattg ttgaaacagt
     8461 cacaaactgt attagaatgt atttttttgg ctttagatag cctaaaaggt ataatagaga
     8521 aaggagggac ttatgcttat ttttccactg attaatgaca cgtcacgaaa aatcatccat
     8581 attgacatgg atgccttttt tgctgcagtt gaggaaaggg ataaccctgc tttaaaagga
     8641 aagcctgttg tgattgggaa agatccaaga gaaacaggtg gtcgcggagt tgtttccact
     8701 tgtaattacg aagcgagaaa atatggcatt cattcggcca tgagctctaa ggaagcttat
     8761 gagcgttgtc ccaaagccat ttttatttca ggaaattatg aaaagtatcg aacagttgga
     8821 gaccagatcc gccgtatttt taagcgttat actgatgtgg tagagcctat gtccattgac
     8881 gaggcttacc ttgatgtgac tgataataag ttggggatta agtcagccgt caaaatagcc
     8941 aagctgattc agcatgatat ctggaaagaa gtaggattga cctgttcagc aggtgtgtct
     9001 tataacaaat ttttggctaa attggctagt gattttgaaa aacctcatgg cctcactcta
     9061 gtcttgaaag aagatgccct gtgcttttta gccaaactcc ccattgaaaa gtttcatggt
     9121 gttggtaaaa aatcagttaa aaaactgcat gacatgggga tttatacagg acaggatttg
     9181 ttggcagttc ctgaaatgac cttgattgat cattttggtc ggtttggttt tgacctttac
     9241 cgtaaagcga gaggcatcag caattctcct gtcaagtctg atcggatacg caagtcaatt
     9301 ggcagtgaga gaacctacgc taaactgctt tatcaagaaa cagacatcaa ggcagagatc
     9361 agtaaaaatg ttaagcgcgt ggccgctctc ttacaagacc ataaaaagtt aggcaagacc
     9421 attgtgctca aagtgcgtta tgctgatttt accaccttga caaaacgtgt caccttgcca
     9481 gaattaacca gaaatgccgc acaaattgag caagtagctg gggatatttt tgacagctta
     9541 agcgaaaatc ctgctggtat ccgcctgtta ggggtaacca tgaccaattt ggaggataag
     9601 gtagctgata tttccttgga cctataggag aaagagtgct ctatccgtcc gcctcatttt
     9661 ggagaaaaaa gaagctgatt agggatttcc ctaatcagct tctttggtcc attattttat
     9721 tacagcatag cttggtctgt atcatcacct ttttcgttaa gggttttagc cttgtaaaaa
     9781 gcaaagccat aaagagcagc ttgtataagg ataaggatag ttccaaccat tgacatggtt
     9841 gttgtgaact ggttaaccaa gccgataaca gaaaggataa ggcctaagat ataaggaata
     9901 taactaaccg ttagaccttg ttttaattta gataagtttt gagcacaaaa gacaatgata
     9961 gcaataatag caaggacatt taagacagat aagaaaatca taaatggtgt catgctgctt
    10021 tgtagctgtg ccaattgctc agttgttaat tgggcccgaa atgcttcatt cttgagttgg
    10081 ctttgtaagt agaaaatccc tgcaaatccc attaatgaca gtacaactcc aagcccgttt
    10141 agaataataa tggcaatagt agacgttttg agtgcctgac gcactttttc ataagaaatc
    10201 atataatcct cctagagtcc ttaatccgaa attgtacaat gtgtttaata caaaaatatt
    10261 ataccataga ttaatcaaaa atgtccgttt ttctaggatt ttttctggaa aaagagggca
    10321 atatctgatt ctgtaagccc tatcatcgaa tcgatagtcg aataattctc aggtgttaac
    10381 ctaaaatcat cattatctga ctgagagttc tcagtggggt tagagtttgt tgattgagag
    10441 gaagattttt gagagtcgtc ctcaagggtt gccgtattag aaaaaaggga ggtctgctct
    10501 tttgatttta gctcttggtt aggttgagag gaggctaagt cggattgttc ttggaagcgt
    10561 tcgatcaagt aggtttggcg tttatcgcct tcgtgtttaa tagcatactc aaaggcagta
    10621 tattctccca acagaattaa cttactttta gaccgagtaa tggccgtgta aatcacattt
    10681 cgttgcaaga gtcggccgct ttggcgtgtg ataggtaaaa tcaccacttg aaactcactc
    10741 ccttgcgatt tatgaatgct catggcatag gccagggtta attttagcca ttcatttcta
    10801 gggtacgtga cttcgctacc gtcaaaatct aagattaatt cgtcttgctt agattcggtg
    10861 tatttagcag gaatcaaatc tgtaatataa ccaatatctc cgttaaagac attcaactga
    10921 gcatcgttga ctaagtgcag gactttatca cctttacgaa aatgcgtatc attgaacaga
    10981 aattctgttt gtccttgcaa gggattgaga agttcttgca tgagttgatt aagatgattg
    11041 atgccagctt gtcctttgta cataggtgct aaaatttgaa tttcctcagc agggatgcca
    11101 cttttaatag cagataggac aattttttga atcatgtcag ggataaaggc tgcttgggct
    11161 tcaaaataag aacggtcagc ttttttatca cgaaagtcag cagctaagat tcctcgacgc
    11221 atctggtctg ccaaattgac aatagtagat tcttgggatt gacgaaatat cttttgcaag
    11281 gcgatttggg gcaggctatt gacttttaaa agatctgaca ggacttgacc gggtccaacc
    11341 gaaggaagct ggtcactatc tccgacaata atcacttgag ttgttgagtt aatagctcct
    11401 aacaactggt tggcaagcca ggtatccacc attgaaaatt catcgacaat cagcaggtcg
    11461 cagtctagat aatcctccat ggcttggtaa tcgttgtcgc cattgaggcc taagtgcctg
    11521 tggatggttg cgctaggaag tccagtcaac tcattcatgc gacgtgcagc ccgacctgtt
    11581 ggagctgcta acaagatagg aaggtctttt ttatccaaat caatctgatg caggttcgcg
    11641 taagcctgca aaatgcctcg aataacagtt gtttttcctg ttccgggacc acctgttagg
    11701 agaaagacct tgctggttaa agccttagta atggcttctt gctgcacttg gtcataggtg
    11761 atggcaaagt ctttttgaac ggcttggatg gttgtttgaa tggtatcatg actaaatgac
    11821 tgacttaaag gagtatctaa gagacgagag atgttgttag caatcccttc ttcagcaaaa
    11881 taaaggctag catcaaacag tttggtgtca ctgtttttga ttttgccctc tatgattaac
    11941 tcgcttagtt gttcagccac agcagcagga tcacattcta cttgacgtgc atcttcaagg
    12001 agtgtgatgg caaagtctaa taattgtcgt gcttggacat aagtatctcc tcgattgatg
    12061 gattcttcca agagacagtg aaggagggct gcacgaaaac gtttcggaga gtcgctttca
    12121 atccctaagt tttcagcgag agcatctgcc attttaaacc caaaaccttg tagatcttcg
    12181 actaactgat agggattttc tttaacaagg tcaagagcct cttctttata cttttcaaac
    12241 gcttgaaggg caaaacggtt gctaaggcca agttcgacga gaccagcaat cagttgctct
    12301 gtgccgtaat tcaattttag tttagcgaca aaggcttgac gattagcctt agataggcca
    12361 gagatagttt ctaatttgct tgggtcttct aaaatatggt caatggtatt atgaccatat
    12421 agcgcaatga ttttctccgc tgttttttta ccaatcccct taaaatggtc gctagagaaa
    12481 taattaacca aaccagatga actaggtttg attttttggt aacggcttag tttgagttgc
    12541 tgtccatatt tagggtgctg ggtcaattcc ccccaaaagg tgtagtcatc tccttcaata
    12601 atgtcagcca tcgttcctgt gataatgatt tcaaagtcgt caatgtcact gtctgtatcc
    12661 tcaatggcaa ggaggagaat tttaaagaaa ttagcctggt tttcaaaaat gatacgatca
    12721 acagtacctg taaaaacgta ttccatagta actctttcta tttatacaag ataactgaaa
    12781 acctgcccaa aggcaggttt tttctaatta aaaacggtca ttttattgag tggccaaaaa
    12841 cgagctttca cttcaccgat aaggttttct tttttgaaac taccaacttc gcgactatcc
    12901 ctggaaacaa tacgatcatc accaagaaga aggtattctc cttttggaac actcatctca
    12961 aagcgtgttt gtccctcaga attagttgta aaagcatcag atgtttctgc taactgttgg
    13021 aatagggtat tataggcgta agttttttgg agtttatcgt ttttaaattg ttttagatac
    13081 tcagccaaat acggctcaac tgttttttta ccattaatat aaagtgtgtc atcattataa
    13141 gaaatggtat cgcctggcaa tccaataact ctttttacga tttctttctt ttgtccgttt
    13201 tcttcttcct gagcaactac aatatcaaag cgatcaattc tagcttgatt aaaaacgata
    13261 aggcgttcgc catgagctag agttgggtcc atagaatggc cgtctacttt aacagcctgc
    13321 cacaaaaaaa gacgagatag accaaagaga attaaaaaga gagtgaatgg gccccattct
    13381 ttaataaact gtttcatatg attcctttta tttagtgaga agcgcttgcg ctttgtgagt
    13441 gttggcgaag tgaagtttag cactatattc taagctagac ataccataag cggctaagag
    13501 ttggctagca actttatctg aagctgaacc agcaccgctt gggagttggt aacctaaatc
    13561 ttgacctaat tgatcgagat tgtctaaaaa tagatttcta gcaatgatag agctaacagc
    13621 cacagccaaa tagtgacttt ctgccttttc ttgaaaggtt agaggatttg ggaaatggtt
    13681 tttttccttt tttagatgct tttcataatt tgattggcta gtgaaagcat caataacaat
    13741 ttgtttaggt tgaatgcctt tttgtaacaa caaaaaaata gcttggttat gaagagcaac
    13801 tttgatagaa atggcattat atggtttact tttaccaacc aattcgttat attttttagg
    13861 tgataggaga agtgattgat gaggtatttg tttctctaac agaggcgcaa tctgttgaat
    13921 ggttttatcc gataattttt tagaatcatc aaccccaagc tttttcagga aggaatgatc
    13981 tttaggatcg acaaaacttg ccacaacagc aatcccacca aaataagagc cattacccac
    14041 ctcatcactg ccgattatag gtatatcttg gctattgttg cttgcttcaa aaactgtctt
    14101 agctactgga agattaagct cttgagctaa agcatttgca ccgtttccct ggagaactaa
    14161 ttttccggat ttgtacagca aaacagtaac cccatttttt ttagcagcaa aggctacata
    14221 ggtattttgg ctactgatgg tgtagggggc tagctgtttt tttaaatgtt tactcagtat
    14281 agcatctatt ttcaaaacta aggtattcat aataattatt ttaacataaa atagttgact
    14341 atggttaatt cataagttta tttaacaaag aaaacagaga ctcgaatgtt tagacgggtt
    14401 agggcaatgg tgttgactat tttacgaaag tttcatttta cggtataatg ctaatgaggt
    14461 gaccctatga aaagtattaa tcgctataaa ttcacctttg gtgaaaaaac attaacattg
    14521 acaactgaca aagacaatct ctttatggaa gaagttgagc gggtagctaa agaaaagtat
    14581 caggctctta aaaatcattt accagaagct gatgacgaga ctatcgctat tttaatggct
    14641 atcaatacct tgtcaacaca attaagcaga gagattgcca ttgaaaaaat ggaagctgaa
    14701 attttagatt tacgtcaaaa aaccttggtt ggtcttcaag aaaaagctaa tcaaatagat
    14761 gtgaatgagg tttaatcatg ttatctttat tgatagtgct tattttaact tggaattttt
    14821 atattggtta tagtagaggt attattcttc aatcgtttta tgtcttagga gccctacttt
    14881 ctcttttggt agctaatcga ttttatattg gattagccca taagctaacg ctttggattc
    14941 cttattctaa cccggtagaa ggaacatcag tctttttctt taaatcagtt gatatctttg
    15001 ttttagataa ggtttattat gcaggccttg ccttttttat cattttctta ttggggtatg
    15061 cattgagtcg ctttcttggg atttttgttc atttcctttt gctaaattat tttgataacc
    15121 agtggacaaa atgtttgagt ggcggactag cgtttctagt atcgcttctt tttttgaaca
    15181 tgttactgtc tatttttgca acggtcccta tgcctttttt acagcactat ttgcactcta
    15241 gttttcttac tcgtttggtg atcgaacacc ttccaccatt gacaataatt attcaaaaat
    15301 tgtggattca agccattatt tgatatcgtt ttgtgactaa tataagaacc tggagtgagt
    15361 ttcaccttta ggttctttat ttacgagaaa ctgtttagaa ataaagagaa cgcatgggaa
    15421 cttagtgact ttcttgcccc attttccatc attttaggta taatgaagag tatgaataac
    15481 aagattttag agcagttaga atttaacaaa gttaaggaat tgctattacc ttatctcaag
    15541 acagaacaat cacaagaaga attattagag ctggagccga tgacggaggc tcctaaaata
    15601 gaaaaaagtt ttaatgaaat ttctgacatg gaacagattt ttgttgaaca tcactcattt
    15661 ggcatagtca gcctaagttc aatctctgag agtttaaaac gcttagagct ttcaactgat
    15721 cttaatattc aagaactttt ggctatcaaa aaagttttac agagttcttc ggatatgatt
    15781 cacttttatt ctgatttgga taatgtttct ttccaatctt tggatcgttt gtttgaaaat
    15841 ttggaacaat tccctaatct gcaagggtct tttcaagcta tcaatgatgg tggtttttta
    15901 gaacattttg cgagtccaga attagagcgt atccgtcgtc aattaacaaa tagtgaacga
    15961 cgggttcgtc agattttaca ggatatgctt aaggaaaaag cagagctttt atcagagaat
    16021 ctaatcgcta gtcgtagtgg acgaagtgtc ctaccagtaa aaaatactta tcggaatcgt
    16081 atttctggtg tggttcatga catctcttct tcaggaagta ctgtttatat tgagcctcgt
    16141 gctgtagtta cactaaacga agagataacg cagcttagag ctgacgaacg ccacgaagaa
    16201 ggtcgtattt tacacgcatt ttcagacttg ttaagacctc atgtcgccac tattagaaat
    16261 aatgcatgga ttcttgggca tcttgatttt gtaagggcta aatatctttt tatgtctgat
    16321 aataaggcga cgatacctaa gatttctaat gacagcacgt tagcattaat caatgttcgt
    16381 catcctctgt taagtaatcc tgtggctaat gacttacatt ttgatcacga tttaactgca
    16441 attgtcatca ctggtcccaa tactggtggt aagacgatta tgctaaaaac actcggttta
    16501 gcacaattaa tgggacagtc tggtttgcca gtattagcgg ataaaggtag taaaattgca
    16561 gtatttaaca atatctttgc agatattggc gatgagcaat ctattgaaca aagtctatca
    16621 actttttcta gtcatatgac gcacatagtc agtattttaa acgaggctga ccacaatagt
    16681 ttagttctct ttgatgaact aggagcagga acggatcctc aagaaggtgc tagtttggcc
    16741 atggctattt tagaacacct taggttaagt catatcaaaa cgatggcgac cacgcactat
    16801 ccagaattaa aagcttatgg gattgagaca aattttgtag agaatgcgag catggaattt
    16861 gatgcagaaa cgcttagccc cacatatcgc tttatgcaag gagttcctgg acgctcaaat
    16921 gcatttgaaa ttgcttctcg ccttggttta gctccattta ttgttaaaca agctaagcag
    16981 atgacagatt ctgactcaga tgttaaccgt attattgaac agttagaggc acagacactt
    17041 gagacacgta gaagactgga tcatattaaa gaagttgaac aagaaaacct caaattcaat
    17101 cgtgcggtta agaaactcta taatgaattt tcacatgaac gcgataaaga gttagaaaaa
    17161 atctatcaag aagctcaaga aattgtagat atggctttga atgagagtga tactatctta
    17221 aaaaaactca atgataagag ccaattaaaa cctcacgaaa ttatagatgc taaggcacaa
    17281 ataaaaaaat tagcacctca agttgattta tcaaaaaata aagtcttaaa taaggctaaa
    17341 aaaatcaaag cagctcgtgc ccctagaatt ggtgatgata ttatagtgac tagttatgga
    17401 cagcgaggta ccttaactag tcaattaaaa gatggccgtt gggaagcaca agtgggaatt
    17461 atcaaaatga cattaacaca agatgaattt agcctcgtta gagtccaaga agaacagaaa
    17521 gtcaaaaata aacagattaa tgtggttaaa aaggctgatg gttctggacc aagagctcga
    17581 cttgatctta gaggtaaaag atacgaagaa gcaatgcaag agttagatca ttttattgat
    17641 caagcattgc ttaacaatat gggacaagtt gatatcattc atggtattgg tacaggcgtt
    17701 attcgtgagg gagtgacaaa atatcttcgt cgtaataagc atgttaagca ttttgcttat
    17761 gccccacaaa atgcaggggg atctggtgcc acaattgtaa cgttagggta aatgatggaa
    17821 tcatatgaac acttttatgc caaactatct caacctttta gaaaaacccc acagttaata
    17881 attcttttaa atgttttact aaaaataatc acaggagtga tgtacatact ttatccatct
    17941 tttctgatat ttacgctttg gcaagggatg acatttcaat tatggttaag gttattaatt
    18001 attcctgctg ttggctttat agctttgtct tacattagga aacgctttga ttttccacga
    18061 ccgtatgaaa aatggaatat taaaccttta attgataagg atacaaaggg aaggtcaatg
    18121 cctagcagac atgttttttc agctacgatg attagtatgt gtttgttacg atattatgtt
    18181 tactttggaa tagtttgttt aatattatcg gctttattgg caatttgccg tgtgatagca
    18241 ggtattcact atcctaagga tgttattgta ggttacctta ttggcttgat gttagggctt
    18301 tgtttattga tttagcgagt tcgtagcaaa tagtttcaaa aacaactaaa ttcttgtaca
    18361 ataggcttat cattaagatg aaatggagaa aaaagatggc attagaagta acagatgcta
    18421 catttgtaga agaaactaaa gaaggtttag tactcattga tttttgggca acttggtgtg
    18481 gtccatgtcg tatgcaagca ccaatcttag aacagttatc tcaagaaatc gatgaagatg
    18541 aactcaaaat tttgaaaatg gatgttgatg aaaatccgga aactgctcgt cagtttggta
    18601 ttatgtcaat tccaacattg atgtttaaaa aagacggaga agtggttaaa caagttgcag
    18661 gtgttcatac taaagaccaa ttgaaagcta ttattgctga attgagttaa ctaaaataaa
    18721 gcccagcgtc acgctgagct ttattttatg acctactaac ttcaatggaa taaccatgta
    18781 aacataaaac gacttgcaaa agcaaaagca acagtaatga ggaaaaatac agtgacaata
    18841 aggggtttct gataaggaag tgttgctctt tcttctcgtt tttcgatttc gtctaataat
    18901 tttccatttg aaacagctag gatttcctta taaggttgca catcatattt tttcttaaaa
    18961 cgttccacac gattagcata agtcatagta attatcgata ataaaacaaa aatgccaagt
    19021 cctagccact ctaagaaata gactaatgga taacttgaaa tcattaatag tatcatcaat
    19081 gttaccatta ctttggtatc tcgtttaaaa ttctttttat caacctgagt gatggtatat
    19141 ttcattttct caatgtctcc tttaatgagt tggtctaagc tcacttgaaa aatttgactt
    19201 aggagtaaga ggctatggat gtctgggtaa gttttgtcat tttcccagtt agatatgctc
    19261 tgacggctta catagacttt ctcggctaat ttttcttgcg agagcgcttg ttgtttacgg
    19321 tagcgaataa tttgctgacc aatttccata aatatcaccg aaaaacttta cagcggcgta
    19381 aaggaattgt aaacaaaaag tgaaccgtta tagttcactt gcgattaagc atttttctgt
    19441 tttaagtagg tctctagcat tttcttttgt ggtgttgcaa agggataaag agaaaagtcc
    19501 tcaattgcta cccactttag gtgaggagca ttaggtaaat ctgttgcttt gaccaccccc
    19561 tctatgagtt ctattgtcca cttctggtga ctaaaagtgt gcttaatatt tggaaagtga
    19621 ttatcagtcc attgtggctt taattgatat tctctttcga aagtttcatt ttgggtttgc
    19681 cagattatgg ggttggattg attgtcatca aataaatcta attgttgaga aagaggtgat
    19741 gtttcgataa taggaaatga ccaaaatcct cctagaagtc tccctttagt atttttctcc
    19801 agtagatact ggccattttg gttacgaatg acaaaagcct gaattcgcat tggtttaggc
    19861 tttttctttg gattttttat ggggtattta ccataagtac cattcaaata agcagcgtta
    19921 aagaaacgaa tagggctttc atcaggccta ggtgtcttag cggattcgat gtctgtacct
    19981 agatccataa gtgcctggtt aaaatcaccg ggtctgtcag ggtcaattag tatttccata
    20041 atagcttgaa aaattttacg atttttaggg tcaccgatat cataattaac ttcaaacaaa
    20101 cgagccatga cacgcatcac attgccatca acagcaggct ctggtaagtt gaatgagatg
    20161 ctggcgatag cacctgcagt ataaggacca atccctttta atgaagcaat atcatcataa
    20221 gtgtgaggaa atatgccacc aaaatcaacc atcacttgct gtgcagcctt ttgcatatta
    20281 cgcacccgag aataatagcc tagtccctcc catgccttta gtaattgttc ttcaggagcg
    20341 tctgccaaat cttttatttg aggaaaccac tctagaaaac gtttataata agggattacc
    20401 gtattaactt gtgtttgttg caacatgatt tcagaaaccc aaatataata tggattagta
    20461 gttcttcgcc aagggagatc acgtttttct tggtcatacc actctaaaag tgtgcgacga
    20521 aaagaagcga ttgtctcatt atcccacata ttaataccat aatcttttaa ttcaatcatg
    20581 ttgttattgt aacacaggag tcttaaaaag agtaaaaaaa gattttaggt atttgcgaaa
    20641 aagaaaagga aatattataa taatattagg tttacctcat ctaaatgttg atttagaata
    20701 actgaaatta acgatagaag cagacaggtt ttaatttgga ggggacatgt tccagaaatt
    20761 aaagaatctt attgatcggt attcgtggtt cgtttttata atgatgattc ttgtgttatt
    20821 tcttaactat atttatccat ttgatccttc tttgagcgga ctacagttgg aatggctgat
    20881 catgacgcaa gtttttcctg gattaggtat cgtatgtgcc atggttgcta ttatttttaa
    20941 aaagattaac ctttttgttt tggccctaat tttatatttt gcactttggt taaaactttt
    21001 ccttgctttt tcttttttca cctatttttt aggagtctga ctaagtgcca atttttaaaa
    21061 ctcgtgaaag aaaatgtttg acaaaactta gtcaagtaga aaaagttcct tgcttttaat
    21121 tgactattag tgtacaataa gattctgtga gtatacctca cttactcact ccaaaagtag
    21181 tgagtcatta gaccaaaagg aggaaaatat caatggctaa atacgaaatt ctttatatca
    21241 ttcgtccaaa cattgaagaa gaagctaaaa acgctttggt agcacgcttt gactctatct
    21301 tgactgacaa cggtgcaact gttgttgaat caaaagattg ggaaaaacgt cgtcttgcat
    21361 acgaaatcaa cgatttccgt gaaggacttt accacatcgt taaccttgaa gcgactgacg
    21421 cagcagctct taacgagttt gaccgtcttt caaaaatcaa tggtgacatt cttcgtcaca
    21481 tgatcgttaa acttgacgct taattccaac taagagggta gtttatgatt aataatgtag
    21541 tactagttgg tcgtatgacc aaggatgcag aacttcgtta cacaccaagt caagtagctg
    21601 tggctacctt cacacttgct gttaaccgta cctttaaaag ccaaaatggt gaacgcgagg
    21661 cagatttcat taactgtgtg atctggcgtc aaccggctga aaatttagcg aactgggcta
    21721 aaaaaggtgc tttgatcgga gttacgggtc gtattcagac acgtaactac gaaaaccaac
    21781 aaggacaacg tgtctatgta acagaagttg ttgcagataa tttccaaatg ttggaaagtc
    21841 gtgctacacg tgaaggtggc tcaactggct catttaatgg tggttttaac aataacactt
    21901 catcatcaaa cagttactca gcgcctgcac aacaaacgcc taactttgga agagatgata
    21961 gcccatttgg gaactcaaac ccgatggata tctcagatga cgatcttcca ttctagtcag
    22021 aatggattga acgaatacga aattatttga gttcgggcta aaaatttaga acttagaatt
    22081 tagatcaact ccctaggaaa tcaagatttc ttgccagttt tctaaaattc agtcgttttt
    22141 taagagccct taacatcata atttataaag gagaaaatac atggctcaac aacgtcgtgg
    22201 cggattcaaa cgccgtaaaa aagttgactt catcgcagct aacaaaattg aatatgttga
    22261 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtggaaaaa ttcttcctcg
    22321 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcaa tcaaacgtgc
    22381 tcgcgttatg gctcttatgc cttacgtaaa cgaagactaa taaacaaaca gtccatttcg
    22441 gactgttttt tagttgacta ggactagtct aggcgtatag gtgagttttt tctaaaagag
    22501 agaatgatag taaacgaaaa tccttgcgta gacagcaagg atgaaatgat tgttatttgt
    22561 taacaggtga catagtgttt tgaatgttgt atttgcgttg taggtaatag cgtaaagcaa
    22621 gggaaacacc accaataatg agcaaggcaa gaggaggcaa ctgtgggtta agagaggttg
    22681 gtaaaaaggc agttgcagag tacaaggcaa tccaaatcaa catggctaat gataaggctg
    22741 cgatgatttt gaaccaactt ggacgaaggc tcttatcttt tccgagatga cggtaaataa
    22801 agtaataagt agcgtacatg gatgctcctc caccaaaacc aagtgccagt aaggaaatca
    22861 atcctgtaac tgtagcgttt gtgttgaaga aggtcatgat gccatttaaa agggcaacaa
    22921 ttccgatgaa tagcaaagag gtatctagcc acatcaacca aggattggtg tttttgtcag
    22981 tttctgctgc tttttgacta gggtcttggc taaaagaagc tgcccaagca gtcggagtgc
    23041 ctaatagatt tcgagcggtg actccttttt tctggttttc gagaatagct ggaatggctt
    23101 cttcgagaat cagcttaatg tcctcatcag acttgccgtc ttggattaat ttgttcgtag
    23161 cggtgtggat aaattcttga ttttttttgg taagttcttg taattccatg ggaatccctt
    23221 ctttatatgg gttagttaaa gtaagtcaat gatattagtt agtgtcaaat gagactttgg
    23281 agccagtcgt ctgacacaga gttttgtcag gtcttaaccg cattctgcag cttactccac
    23341 tctagaacca tttttttcta ataaagtaaa tcacaacaaa ggaactaagg agcatagcaa
    23401 tcaaggtgat ataccaaaaa gcatgttcta ggccatttag tggtaaccag ttgttttgga
    23461 aattcatacc ataggcggag aaaatcacag ttggtatatc taaagccatg gtcatcaagg
    23521 ccagtgtttt cataatggtg ttctggttat tgttgataat agaagcagtg gtttcggtca
    23581 tggcattcaa gacattttca taaatgccag ccatctcaat cgcctgttgg gtttcaatca
    23641 aggtatcttc tagcaaatcc tcgtcctcaa tgtatttctt gagagagctt gttgagctgg
    23701 ataatttctt gacgatgcgt tcgttgaatt tcaaggaagc ctttaagtag acaatggatt
    23761 tttcaagttc catcatgtcg ataagttctt catttcgagt agctgcttca agctgagctt
    23821 ccaaacgttc gctttggcga tcaatggtcc tcaaggcagt cagaaagagc tcggcgttgc
    23881 gatatagaat ctgaaaaaca aaacgtgtct tcatgaaggt atagaaattt ttgacccggc
    23941 ggttgtgaaa atgatcgaaa agggtcatgt catgcagaca agttgtgata acagcatttt
    24001 ccgttacaat aatgcctaaa ggcatagtaa tatagtaact tttattgtta cgttcttcgt
    24061 atatcgggac gtctacgata attagggtat aatcatcttc tacggcaata cgtgaggttt
    24121 cttccacgtc caaaggggcg cgcaagtcag aaatatcaat gttaaattga tcggcgatct
    24181 tcatagactc ttcttgggaa gggttaacca gtttaatcca agctcctggc tcgaatgttt
    24241 ctatttcttt gaattcaatt gccgatgaaa gaaacatttg tttcatgaca agccctcctt
    24301 tttgatgatt aactggtaga gattgacatc aaaccttgat aataaagtct tctcaaggat
    24361 tttctgaaaa attctcaata cttatctatt ataccaaaat tcgcaaagtt tggggcaata
    24421 ggttatcaga aatttttgtt ataatataag aaagctcgat gaggagggtg cctttaggca
    24481 cattcaagat gcaaaataaa ataataattc atggggcaag agcccacaat ttaaaaaata
    24541 ttgacgtgga aattccacga gacaaattag ttgtcgtgac agggttatca gggtcaggaa
    24601 aatctagtct agcctttgat actatttatg cggaagggca acgtcgttac gtagaaagtt
    24661 tatcagctta tgctagacag ttcttgggta atatggaaaa accagatgtg gattccattg
    24721 acggtcttag ccctgctatt tccattgacc aaaaaaccac cagtaagaac cctcgctcaa
    24781 cggttggtac ggttacggaa atcaatgatt atttacgtct actatatgcg cgtgtgggca
    24841 caccttactg tatcaatggg catggtgcta tcacggcgtc ttctgcagaa caaattgtag
    24901 agcaggtctt agccctccct gaacggacac gcatgcagat tttagctcct gttgttcgtc
    24961 ggaagaaggg gcaacacaaa acagtttttg agaaaattca aaaagacggc tatgtccgtg
    25021 tgcgcgttga cggggatatt tttgacgtga cagaagtgcc agagttgtcc aaaagtaaga
    25081 tgcacaacat tgaggtggtt attgaccgtc tggttaataa ggatggtatt cgtagccgtt
    25141 tatttgattc ggttgaagca gctttaaggc tgggagatgg ctaccttatg attgacacta
    25201 tggatggcaa tgaactgctc ttttctgagc attattcctg tcctgtctgt ggatttacgg
    25261 ttcctgaatt agaaccaaga ctcttctctt ttaatgcgcc gttcggctct tgtccgacct
    25321 gtgatgggct aggcattaag ttggaagtgg atttggactt ggttgttcct gacccaagta
    25381 agtctttgag agagggagct ttggcgcctt ggaatcctat ttcctccaat tattacccaa
    25441 ccatgcttga gcaagctatg gcaagttttg gggtggatat ggatacacct tttgaggcct
    25501 tgactgagga agaaagagat ttagtgcttt atggttcagg tgatagagaa tttcattttc
    25561 actatgtgaa tgattttggt ggtgagcgta acattgacat tccttttgaa ggtgttgtaa
    25621 ctaatgttaa tcgccgttat cacgaaacta atagtgatta tacgcgcaat gtgatgcgtg
    25681 gttatatgaa cgaattgacc tgtgcgactt gtcatggtta ccgtttgaat gaccaagctt
    25741 tgtgtgtgca tgtgggtggc gaagaaggac ctcatattgg tcaaatttca gaattatcga
    25801 ttgccgacca cttgcagtta ttggaagaat tggaactcac agaaaatgaa agtaccattg
    25861 ctaaaccgat tgtcaaagaa atccatgacc gtctgacatt cttaaataat gtgggactga
    25921 attatctgac cttgtcacgg gctgctggga ctttatcagg tggtgaaagt caacgaatca
    25981 ggttagcaac acaaattggt tctaacctat caggggtgct ctatatcttg gatgagcctt
    26041 ctattggatt gcatcaaaga gacaatgacc gtttgatcga gagcctgaaa aaaatgcgtg
    26101 atttgggtaa tacgttaatt gtggtagaac acgatgaaga caccatgatg caggcagact
    26161 ggctgattga tgtgggaccg ggggcaggtg agttcggtgg agaaattact gcctctggaa
    26221 cgccgaaaca agtggctaag aataaaaaat ccatcacggg tcaatatttg tctggtaaaa
    26281 aattcattcc agtgccttta gagcgccgtt ctggtaatgg ccgattcatt gaaataaaag
    26341 gagcagcgca gaataatctt caaagcctcg acgtgagatt cccactgggt aaatttattg
    26401 cggtcacagg ggtatcaggc tcagggaaat caaccttggt taatagtatt ttgaaaaagg
    26461 ctgtcgccca aaaattaaac cgtaatgctg ataagcctgg taaatatcac tctatttctg
    26521 gtattgaaca tattgaacgc ttgattgaca ttgaccaaag tccgattgga aggacgccac
    26581 ggtcaaatcc agccacctat acgggtgtct ttgatgatat tcgagacttg tttgcccaaa
    26641 ccaacgaagc taagattcgt ggttacaaaa aaggccgttt ctcttttaat gtcaaaggtg
    26701 ggcgttgtga ggcttgttca ggtgatggga ttatcaaaat cgaaatgcac tttttgccag
    26761 atgtttatgt gccttgtgag gtttgccacg gcagacggta taattctgag acgcttgagg
    26821 tgcattacaa aggaaaaaat atcgcagaag tccttgatat gactgtcgat gatgccttgg
    26881 tatttttctc tgctattcct aaaatcgctc gaaaaattca aacgattaag gatgttggac
    26941 ttggttatgt gaccttaggt caaccagcta ccaccctctc tgggggagaa gctcaacgga
    27001 tgaagttggc tagtgaattg cacaaacgct cgacaggtaa gagcttgtat atcctagatg
    27061 agccaacgac tggtttacac acagatgata ttgcaaggct attaaaagtt ttggaacgct
    27121 ttgtagacga tggtaatacg gttcttgtga ttgagcataa tttggacgtt atcaaatctg
    27181 ctgaccatat tattgactta ggaccagaag gtggtgacgg aggtggtcag attgttgcca
    27241 cggggacacc agaagaggta gctcaagtta aagaaagcta tactggtcat tatttgaaag
    27301 taaaactaca acaataggat taggagttcg tttgagctcc ttttaatctt ttaaatgctc
    27361 tcaaatcatg gtaaacttaa agtagttttt tcatgctaca atattctcaa aagttaccaa
    27421 aggagttcgc gatgtcagga tttttagaac aacgattagg tcactgccta aggcagatgg
    27481 cagagaaggg gctagaggct cttctagtca cccatttaac caatagttat tacttgacag
    27541 gtttttctgg aactgcagca actgttttga taacggccaa acgtcgtgtt ttgatcacag
    27601 attcacgtta taccttgctt gctaaagcta gtgttgaggg atttgatatt atcgaaagcc
    27661 gcacgccgct taaggttgtg gcagaattgt tagaggctga tcaaatagat tgccttggtt
    27721 ttgaggacca ggtatcgttt tctttttacc aggccatgca agcagaactg tcaggaataa
    27781 ccttgcttgc tcagtcaggt tttgtggagc atttacgtct tattaaggac gcctctgaaa
    27841 tcgataccat tgctaaagcg tgctcgatct cagacaaagc atttgaagat gctcttgatt
    27901 ttattaaacc agggacaacc actgaacgtg acctggctaa ttttttagat tttcgtatgc
    27961 gtcagtatgg tgccagcggc acatcatttg atatcattgt agcttcaggc tatctctctg
    28021 ccatgcctca tggacgcgcc agtgacaagg ttatccagaa taaagagagc ttgaccatgg
    28081 actttgggtg ttactacaat cactatgtta gtgatatgac gaggaccatt catattggcc
    28141 aagttactga tgaagaacgt gagatttatg ctcttgttct tgctgctaat aaggctttaa
    28201 ttgctaaagc tagcgctggc atgacttata gtgactttga cggtattccg cgccaactca
    28261 tcactgaggc gggttatggc agtcgcttca cacatggcat tggtcatggc atcgggcttg
    28321 acatccatga gaatccattt tttgggaaat ctgagcaact tctccaagct ggaatggtgg
    28381 taacagatga gccaggtatc tatttggata acaaatatgg tgtccgtatt gaagatgact
    28441 tggttatcac aaaaactggt tgtcaagtct tgaccttggc acccaaagaa ttaattgtat
    28501 tgtaaaagaa tggttcagga aaggattagg ggagaagcaa tgacaaatcg tttatcatgg
    28561 caagactatt ttatggccaa tgcagagctg atttccaagc gctctacctg tgatcgcgcc
    28621 tttgtgggag ctgttttggt aaaggataac cgcattattg ccacaggtta caatggcgga
    28681 gtttctgcta cggataactg caacgaagcg ggtcattata tggaagacgg acattgtatt
    28741 cgcactgttc atgctgaaat gaatgctttg attcaatgtg cgaaagaagg aatttcaacg
    28801 gacggaactg aaatttacgt gactcatttt ccttgtatta actgcactaa ggcgcttttg
    28861 caggcgggga ttacaaagat tacctataaa gcacattacc gtccgcaccc ctttgccatt
    28921 gaactgatgg agaaaaaagg ggttgcctat gtgcaacatg atgtgcctca aattgtttta
    28981 ggaggcgata aggaacaata gaaagtgtac ctaaaaggac ggtcataaaa gatttgagcc
    29041 aaggccactt ttgtggtaaa atgaagtgat aaatatttta gtaagaggta ataataatga
    29101 ttgaagcaag taagcttaaa gcaggtatga catttgaagc agaaggaaaa ttaatccgtg
    29161 tccttgaagc tagccaccac aaaccaggta aaggaaacac tatcatgcgt atgaaactac
    29221 gtgatgtgcg tacaggttct acttttgaca caacttaccg cccagatgaa aaatttgagc
    29281 aagccatcat tgaaactgtc ccagcacaat acctatacaa aatggatgac actgcttact
    29341 tcatgaacac tgacacttat gatcagtacg aaattccagt tgctaacgtt gagcaagaat
    29401 tgctttacat tcttgaaaac tcagacgtga aaatccaatt ttatggaagt gaagtgattg
    29461 gggtaacggt tccaacaact gttgaattga ccgttgcgga aacacaacca tctattaaag
    29521 gagcgacagt gacgggttca gggaaacctg caactcttga gacaggactt gttgttaacg
    29581 ttccagactt tatcgaagct ggccaaaaac taatcattaa cactgcagaa ggtacttacg
    29641 tttctcgtgc ttaatccttt gtcaaaacag attagtctaa aaaagagaaa ggaaatgcta
    29701 tgacaactga atatatcggt gaaatcgtca tttcaccacg agtgcttgag gttattacgg
    29761 ggattgctac gacacaagtt gagggcgtcc actcactcca taacaagaaa atggcagata
    29821 gctttaacaa agcaagtctt ggtaaagggg tttatctcca gacagaagaa gatggaagtg
    29881 ttacagcaga tatttatgtt tacttgcaat atggagtcaa ggtcccgact gtatctatga
    29941 atattcaaaa aacagtcaaa tctgctgtgt acgatatggc agaagtgcct atttctgcag
    30001 ttaatatcca tgttgaaggt attgttgcgg aaaagacacc aaaaccagat ttgaagtcac
    30061 tttttgatga ggatttcttg gatgactaac agctttcaaa attcaagaag agatttgcgt
    30121 gaacgtgcct ttcaggcttt atttaacata gagatgggag ctgagttatt ggcagcttct
    30181 cagtttgcct atggttatga taaagtaaca ggggaggacg ctcaagtatt ggagctgccg
    30241 atttttttat taagtcttgt gacgggtgtc aataatcata aagaagagtt ggataacttg
    30301 atatcaactc atttgaaaaa aggttggtcg ttagaacgct tgacactaac agacaaaacg
    30361 ttattacgac taggtctttt tgaaatcaag tattttgacg aaacaccaga tcgtgttgca
    30421 ctaaacgaaa tcattgaagt agctaaaaaa tattctgatg aaacctctgc taaatttatt
    30481 aatggcttac ttagccaata tgtctcggga gctccttcag caaataaatc ataataagtc
    30541 ggagcaatct taggattgta tccgattttt tcaatttatg tacgaatatt aaaagacaaa
    30601 caagcatact ctcgcatcta gaaagagtaa gcttgtttgt cttttagagt aattagtgat
    30661 tggttatgtt ttgtttaaat acttgctcct ggaagtagcg taatcggtaa aatatagtct
    30721 ttactggttt tttctttttt aatttttttg atgagtattt cgacactcaa tttagcaatc
    30781 tcatcaatag gttgacgaat ggtcgctaat tgaggaacat attgctggat aaatgtcgtt
    30841 ccatcataac ctatgacttt catatcctct ggaatagtaa tgtgaagttg tttggctact
    30901 ttcataatga ggatagcagt taaatcatca gaaacgaaaa ggccatcagg ttttcgggtt
    30961 gccaaaatgg atttaatttc catttcgcgt ctaacaggag ataggttatt tggtaatttg
    31021 atgatttctg cacttcgttt gagctggtag ttaaacccta gctggcgcaa ccctgtgggc
    31081 gaatcagaat tgtcattacc tgtaatcatg acaatgtttt gacaaccgtg tttttgcaaa
    31141 gtttgtgcgg ctaatttacc accttcaaaa ttatctgaag aaataaccgg gatatttggc
    31201 gctagattac ggtcaaaagc tacaatagga gcttcgacac gctcataatc ctcaattccc
    31261 aaattatgac tggaagaaat aatgccgtcc acttgattgg ccgcaagcat ttctaaatat
    31321 tcgcgttctt tgacgggatt atgttcacta ttgcaaataa tagttttgta gccctgttta
    31381 aacaattcaa tttccaaatg ttcaattaat tcagcgtaaa agatattgct aatgttgggg
    31441 aagataagcc caatgagttg ggttgattta ccttgcaaac ttctagcgag attgttaggc
    31501 ttgtagccca attcacgcat ggccttattc accttattca ctgttttttg ggaaaggtag
    31561 ccttttttgt tgattactcg cgaaacagtt gttggactga cacccgccaa ggctgccacg
    31621 tctgttaatt ttgcgaccac ttgcctaata cctcatttca taataatgtc caaaagcttg
    31681 tccttctact acttggatac ctgtttgtcc gtgggttggg aaaacccgac tagttaggac
    31741 tttttgccct tggttaataa agatttcaag aatggaattg tccacataga cattaagtgt
    31801 aacatggcct tgtgggattt ggcaagagcg caccgtacca tagtcttggg catattgaac
    31861 ccctgcccga cttcggtcaa tgcttaactg tccttttgtt gtatccactt tcaatcttag
    31921 gccattccct ttttggtcgg caaataggag caggtcaagc tttttttggc ctggaatcgt
    31981 caattccaat tcataacagt tagaactgtc tattttatta tgaaataatt ctgctggccc
    32041 tcgaagattt tgtagggctg aaacaggtgt ttgatagaga attccgtctt taatccttaa
    32101 ttctttcact aaactaagag ctccttgata gtcataacga tctgtcggat aatcaatatc
    32161 tggtaaccca atccaagaca cggctagaac cctgccatct ggactactaa aggcttgagt
    32221 ggcataagct tcaaaaccaa agtcaagatt ttgaagggcc cctccaccca gcaattggcc
    32281 agtttctgga ttgaagcttt caaaaatttt ataggtattg gggtagatat tttgataatc
    32341 taaatcagct ttagccagtc cttgtgggct gaaaatcaaa acaggcttgt catcgacaaa
    32401 cacaaggttg gggcattcaa tcatgtattc cgtaccagaa tcgtcaaagt ccaaatcggc
    32461 tataaatcgc cagttgtcca catgattgtc cacagctttg taaagtttga tttttccttt
    32521 gccatctaaa ccttgggcgc caataatagc atagaattga ccttgataag aaaaaagctg
    32581 aggatcccga aaatgttctg taacatcatc gggctgttca atcaaaacct gtggtatttt
    32641 ggaaatattt ccttgtttat ccatccatgc gccaacctgt aatggtgttc tgacccaatt
    32701 ggcatcgcga acattaccag tgtaaaagag gaagagcttg tcatcaatag catatgcaga
    32761 acctgagtaa gccccatgac tatcgtgagc gtggtctggc agaaggcggc tccttgtttc
    32821 cgtaaaatgg acgaggtctg tggatgtcat gtgtacccat tgtttcagac catgcgcagc
    32881 gccataaggc cagttttgat aaaaaagatg gtagcgaccg ttgaaataag aaaacccatt
    32941 ggggtcattg agtaatcctg tcttaggttc gacatgaaat tggctgtgcc atggggattg
    33001 ggccattttt tcagtaatag cttggtagtc ttttgagctc cactctttgt aagggcggta
    33061 gcgaatagct tgtggtagat ccatcaaaat ctccttgttt tatagtcgtc ttcaagaata
    33121 tactaaacgt tttctgttta aaaatcaaga atttaaagca tataaaataa aaatatgtta
    33181 aacgcttgac ataaaaaata ttagtgataa aatgatagtc aagaagtgaa gcggattcac
    33241 tagcgttggt cctgcacatt cttagccaca aagctggcag aatggatgag ggactaacac
    33301 caaatgaaaa aggagacttt taggcatgga taatcgtcag attgcagctg aagtgattga
    33361 ggctttaggt ggccgagaaa atgtgagaag tgttgcccac tgtgcaactc gccttcgcgt
    33421 gatggtttat gatgaaggaa agattgataa ggaaaaagca gaagctattg acaaggttaa
    33481 aggagctttc tttaactctg gtcaatatca gatgattttt ggaactggta ccgttaataa
    33541 catttatgac gaagttgttg ctcttggttt acccacgtca tcaaccagtg agcaaaaggc
    33601 agaagcaggc aaacatggca atatcttcca acgggcgatt cgtacgtttg gagatgtctt
    33661 tgttcccatt attccagcta ttgtagcaac gggtctcttt atgggggttc gtggtttggt
    33721 gacccagcca gctattatgg atttatttgg ggtgcatgag tacggggaaa attttctcat
    33781 gtacactcgt attctaacgg atacagcctt tgtctacttg ccagctttgg tggcttggtc
    33841 agcctttagg gtctttgggg gtaatcctat tatcggtatt gttttaggat tgatgctggt
    33901 ttccaatgag ttgcctaatg cttgggtagt tgcctctggt ggagatgtta agccgctaac
    33961 cttctttgga tttgttcctg ttgttggtta tcaaggtacc gttttacccg ccttctttgt
    34021 tggtctggta ggagctaagt tggagaaatg gttgcacaaa aaggttccag aagctttgga
    34081 cttattggtc acaccgtttt taacgtttgc tattatgagt accttgggac tatttgtgat
    34141 tggaccagtt ttccattctc ttgaaaacct tgttctggct gggacacagg ccgtcttgca
    34201 tttgccgttt ggcattgcag gcttgattgt tgggggaatc caacaattaa tcgtagtgac
    34261 tggtattcac catatcttta acttcctaga agcgcagctg attgccaata ccggaaaaga
    34321 tcctttcaat gcttacctaa cagcagcaac agctgctcaa gctggagcta ccttagctgt
    34381 tgctgttaaa accaaatcaa caaaactaaa aggtctggcc tttccatcaa ccttgtcagc
    34441 tcttttaggg attactgaac cagctatttt tggggtcaac ctccgttatc caaaagtctt
    34501 tgtttcaggt cttattggtg gtgccttagg tggttgggtc gctgggctct ttggcattgc
    34561 aggaactggt tttgggatta cggtcttacc aggaactctc ctttacttga atggccaatt
    34621 attacaatac cttgtgacta tgcttgtcgg tcttggggta gcctttgcaa ttgcttatac
    34681 ttggggttat caagatagag aaacccttcc gttaccagct gtcgaagttg atcaaacggc
    34741 tgatcagcca gccttagcag aggaaacttt atatagtcct ttgaatggaa cagttgtaga
    34801 cttatctgcg gtttcagacc ctgttttttc atcaggtgct atgggtcaag gcttagcaat
    34861 taagccagaa gataataccc tatactcacc agttgatggt aaagttgaaa ttgtctttga
    34921 aacaggtcat gcctatgcta taacgtcaag tcaaggagca gaagtgttac ttcatattgg
    34981 tattgatacc gtgtcgatgg caggagatgg ctttgaatct cttgtagcag taggtcaggc
    35041 ggttaaaaaa ggtgatcttc ttggacactt tgatcctagc aagattgcag aagctggact
    35101 agatgacacc accatgatga ttgtgaccaa tagcgctgac tatcaaagcg tggacattct
    35161 tgctcaagga catgttttga ttggtgatca agtggcactt atcaaataag gacaaaagag
    35221 ctaactaagc agctcttttg tcctgccatg gatggcaggt tggcaaaaaa atgagaaaag
    35281 cctaaaaacc ttaaatttgt gttattttac ctatactttg taccttgttt tttttaataa
    35341 agtgttgtta tacttaaggc gaactatagg aatgcgctta catggatggt atatcaactg
    35401 ggaagccatg acttagtacc aaaaataagg agtgtccaaa tggataaaca tttgttggta
    35461 aaaagaacac tagggtgtgt ttgtgctgca acgttgatgg gagctgcctt agcgacccac
    35521 catgattcac tcaatactgt aaaagcggag gagaagactg ttcaggttca gaaaggatta
    35581 ccttctatcg atagcttgca ttatctgtca gagaatagca aaaaagaatt taaagaagaa
    35641 ctctcaaaag cggggcaaga atctcaaaag gtcaaagaga tattagcaaa agctcagcag
    35701 gcagataaac aagctcaaga acttgccaaa atgaaaattc ctgagaaaat accgatgaaa
    35761 ccgttacatg gtcctctcta cggtggttac tttagaactt ggcatgacaa aacatcagat
    35821 ccaacagaaa aagacaaagt taactcgatg ggagagcttc ctaaagaagt agatctagcc
    35881 tttattttcc acgattggac aaaagattat agcctttttt ggaaagaatt ggccaccaaa
    35941 catgtgccaa agttaaacaa gcaagggaca cgtgtcattc gtaccattcc atggcgtttc
    36001 ctagctgggg gtgataacag tggtattgca gaagatacca gtaaataccc aaatacacca
    36061 gagggaaata aagctttagc caaagctatt gttgatgaat atgtttataa atacaacctt
    36121 gatggcttag atgtggatgt tgaacatgat agtattccaa aagttgacaa aaaagaagat
    36181 acagcaggcg tagaacgctc tattcaagtg tttgaagaaa ttgggaaatt aattggacca
    36241 aaaggtgttg ataaatcgcg gttatttatt atggatagca cctacatggc tgataaaaac
    36301 ccattgattg agcgaggagc tccttatatt aatttattac tggtacaggt ctatggttca
    36361 caaggagaga aaggtggttg ggagcctgtt tctaatcgac ctgaaaaaac aatggaagaa
    36421 cgatggcaag gttatagcaa gtatattcgt cctgaacaat acatgattgg tttttctttc
    36481 tatgaggaaa atgctcaaga agggaatctt tggtatgata ttaattctcg caaggacgag
    36541 gacaaagcaa atggaattaa cactgacata actggaacgc gtgccgaacg gtatgcaagg
    36601 tggcaaccta agacaggtgg ggttaaggga ggtatcttct cctacgctat tgaccgagat
    36661 ggtgtagctc atcaacctaa aaaatatgct aaacagaaag agtttaagga cgcaactgat
    36721 aacatcttcc actcagatta tagtgtctcc aaggcattaa agacagttat gctaaaagat
    36781 aagtcgtatg atctgattga tgagaaagat ttcccagata aggctttgcg agaagctgtg
    36841 atggcgcagg ttggaaccag aaaaggtgat ttggaacgtt tcaatggcac attacgattg
    36901 gataatccag cgattcaaag tttagaaggt ctaaataaat ttaaaaaatt agctcaatta
    36961 gacttgattg gcttatctcg cattacaaag ctcgaccgtt ctgttttacc cgctaatatg
    37021 aagccaggca aagatacctt ggaaacagtt cttgaaacct ataaaaagga taacaaagaa
    37081 gaacctgcta ctatcccacc agtatctttg aaggtttctg gtttaactgg tctgaaagaa
    37141 ttagatttgt caggttttga ccgtgaaacc ttggctggtc ttgatgccgc tactctaacg
    37201 tctttagaaa aagttgatat ttctggcaac aaacttgatt tggctccagg aacagaaaat
    37261 cgacaaattt ttgatactat gctatcaact atcagcaatc atgttggaag caatgaacaa
    37321 acagtgaaat ttgacaagca aaaaccaact gggcattacc cagataccta tgggaaaact
    37381 agtctgcgct taccagtggc aaatgaaaaa gttgatttgc aaagccagct tttgtttggg
    37441 actgtgacaa atcaaggaac cctaatcaat agcgaagcag actataaggc ttaccaaaat
    37501 cataaaattg ctggacgtag ctttgttgat tcaaactatc attacaataa ctttaaagtt
    37561 tcttatgaga actataccgt taaagtaact gattccacat tgggaaccac tactgacaaa
    37621 acgctagcaa ctgataaaga agagacctat aaggttgact tctttagccc agcagataag
    37681 acaaaagctg ttcatactgc taaagtgatt gttggtgacg aaaaaaccat gatggttaat
    37741 ttggcagaag gcgcaacagt tattggagga agtgctgatc ctgtaaatgc aagaaaggta
    37801 tttgatgggc aactgggcag tgagactgat aatatctctt taggatggga ttctaagcaa
    37861 agtattatat ttaaattgaa agaagatgga ttaataaagc attggcgttt cttcaatgat
    37921 tcagcccgaa atcctgagac aaccaataaa cctattcagg aagcaagtct acaaattttt
    37981 aatatcaaag attataatct agataatttg ttggaaaatc ccaataaatt tgatgatgaa
    38041 aaatattgga ttactgtaga tacttacagt gcacaaggag agagagctac tgcattcagt
    38101 aatacattaa ataatattac tagtaaatat tggcgagttg tctttgatac taaaggagat
    38161 agatatagtt cgccagtagt ccctgaactc caaattttag gttatccgtt acctaacgcc
    38221 gacactatca tgaaaacagt aactactgct aaagagttat ctcaacaaaa agataagttt
    38281 tctcaaaaga tgcttgatga gttaaaaata aaagagatgg ctttagaaac ttctttgaac
    38341 agtaagattt ttgatgtaac tgctattaat gctaatgctg gagttttgaa agattgtatt
    38401 gagaaaaggc agctgctaaa aaaataaaca aagtaacttt cttagatagc aacattcaga
    38461 ttaaattaac aaaatgtgac tatgataaag gtttgctgga attgattaac caaaagacta
    38521 aaaatctgag atgaatagtc ccagattttt agtcttttat aggttttgat gacataaagc
    38581 taaataatcg ttagactacc agaaagtggc gcttgtccgt gagacatggc tgtcttgata
    38641 agagcctgtg tcatcataaa gataaaaaag aacaagaaaa aggagaaaac atgggaaaat
    38701 tatatggaag cattgaagct ggtgggacaa agtttgtctg tgccgtgggt gatgaggagt
    38761 ttacagtggt ggataaaaca caatttccga ccaccacacc agaagaaacc atcgcgcgaa
    38821 ccatcgctta ttttaaagct tttgaggcag atttggctgg aatggcgatt ggttcttttg
    38881 gaccaattga tattgatccg tcgtcagaga cttacggtta tatcacaacc actcctaaat
    38941 caggctgggc taatgtggat ttgttaggac aactttcggc tgcttttaag attccttttg
    39001 atgtgacaac agatgttaat agctctgctt atggtgaggt gcttgctcgt cctggtgtgg
    39061 aaagtttggt ctattacacc ataggtactg gtattggggc gggagctatt caacatggcc
    39121 actttattgg gggtttaggt catacagaag cgggtcatac ctatgtcatg ccccatcctg
    39181 atgatatggc caagggattt ttaggtgttt gcccttttca taaagggtgt ctggaaggga
    39241 tggcagcagg tccaagtatt gaggccagaa cgggagtgag aggtgaacgg cttgatcagg
    39301 aagctgatgt ttgggacatt caagccttct acattgccca agcagcgctg caagcaacta
    39361 tgctttaccg tcctcaagtg attgtttttg gcggaggtgt catggcgcaa gaacatatgg
    39421 tgttgcgcgt gcatgataaa ttcactgccc ttttaagcgg ttatttgcca gtccctgatt
    39481 tgacagacta cattgttact ccagctgttg ctgataatgg ctccgctact ctgggaaatt
    39541 ttgctttggc caagttggct gcacaaggaa aatagggtct gtttttgcct gcttgtctag
    39601 taaaagaaag cgcagtcagc tagaacatgc tataataaac agagattaac atcagaagcg
    39661 aggaatatta tgtcagaacc attatttcta aaatcaacca tgcacgacag gatttggggt
    39721 ggcaccaagt tgagagatgt ctttgcttac aacatcccaa gtgacaccac aggtgagtat
    39781 tgggctattt ctgctcatcc taatggtgtt tcgacagtta ctaatggacg ttatcaagga
    39841 caacctttaa acacattata tgcgcaagag ccggccttgt ttgggaatcc aaaggaagaa
    39901 gtttttccac tgttaactaa gattttagat gctaatgact ggctaagtgt ccaagttcat
    39961 cctgatgatg cttatggacg tgaacatgaa ggagaattag gcaagacaga atgctggtat
    40021 attatttctg ccgaagaggg ttctgaaatt gtatacggcc atcaggccaa gtccaaagaa
    40081 gaccttcgtg ccatgattga agcaggcgct tgggatgatt tgctgactcg tgtcccagtc
    40141 aaagcaggcg attttttcta tgttccaagt ggcaccatgc atgcgatcgg caagggaatt
    40201 cttattttag aaacccagca gtcatctgat accacttatc gggtttatga ttttgaccgt
    40261 aaggacgtta atggtaatct tcgtgacctt catattgaaa agtctattga tgtcttaacg
    40321 attggtaagc cagaaaatag cgtgccagcc actatggttt tggataatat ggtagcaaca
    40381 actttagtct caacaccatt tttcactgtt tacaaatggg taactagtca aatggttgac
    40441 atgaaacaag ctgcgcctta tcttttagtg agtgttttaa aaggtcaagg aaaactctat
    40501 gtggaccaga aggcttatga gctagaaaaa ggcatgcact ttatcttgcc taacgatgtt
    40561 aaatcgtggt catttgatgg tcaattagaa atgattgtga gtcaccccaa tcaactcgtt
    40621 taataccatg gtatcaatat gagaaaaaag gataaaatta tgactctctg tttctctgat
    40681 aactttac
//
LOCUS       DAUGJR010000015        37604 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUGJR010000015 DAUGJR010000000
VERSION     DAUGJR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37604
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.015"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..227)
                     /locus_tag="VH800_000761"
     CDS             complement(<1..227)
                     /locus_tag="VH800_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361840.1"
                     /translation="MTIDEALQNLRDNFNKIMNVLKNDWKALLFLAIAIFGMMVTVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRA"
     gene            complement(224..394)
                     /locus_tag="VH800_000762"
     CDS             complement(224..394)
                     /locus_tag="VH800_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361841.1"
                     /translation="MKRYIEVKDEWKSATDHLNDFIDKNKYAKVTVVGYQVVQLSPYG
                     RDLTYILAEVEE"
     gene            complement(391..627)
                     /locus_tag="VH800_000763"
     CDS             complement(391..627)
                     /locus_tag="VH800_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEQ8361842.1"
                     /translation="MIEELVHKPKHYNHGEIDLIESWYKTYPWDQFVAIMESHIDKYI
                     KRHRYKGNATQDLEKALEYTKRLIEYWLIESVEE"
     gene            complement(869..1225)
                     /locus_tag="VH800_000764"
     CDS             complement(869..1225)
                     /locus_tag="VH800_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361843.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADKEEADRVYRSVKYYKKL
                     NRLPPPDVLEWFQRIYTTKEMIMLIKQSYRLKQKKTDEDDKIYEKWMFKNYGDVKLVK
                     KIKRTDALERARRMGL"
     gene            complement(1222..1662)
                     /locus_tag="VH800_000765"
     CDS             complement(1222..1662)
                     /locus_tag="VH800_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEQ8361844.1"
                     /translation="MVKFIIPIEPKPQKRPRFSRWSGAYEDGDMMAWRKQVTDYVKNN
                     YEGPYFDDGLKVDVTFYLKAPELVSKKPSERAKDKTKQKYQDYINELLYVPKKPDLDN
                     LEKAVYDSISKSEVVWTDDNIIVEHTTRKLYSPNPRIEVKINEL"
     gene            complement(1662..1865)
                     /locus_tag="VH800_000766"
     CDS             complement(1662..1865)
                     /locus_tag="VH800_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361845.1"
                     /translation="MANRYRQRIYAVYDGDSFVDVGTKHELAERLGVTADTIVFIASP
                     AHKKRRPDGRHAEFIGYEDELEE"
     gene            complement(1871..2296)
                     /gene="ssb"
                     /locus_tag="VH800_000767"
     CDS             complement(1871..2296)
                     /gene="ssb"
                     /locus_tag="VH800_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8361846.1"
                     /translation="MINNIVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGER
                     EADFINCVIWRQSAENLANWAKKGALIGVTGRIQTRNYENQQEQRVYVTEVVAESFQM
                     LESRNSQQQSGQDNSSQNDNSQPFGNSNPMDISDDDLPF"
     gene            complement(2289..2963)
                     /locus_tag="VH800_000768"
     CDS             complement(2289..2963)
                     /locus_tag="VH800_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEQ8361847.1"
                     /translation="MRKSESITEYAKAFCKAQLEVKQPLKDKDNPFFKSKYVPLENVT
                     EAITKAFANNGISFSQDPTTNAENGYIDVATLVMHTSGEWVEYGPLSVKPTKNDVQGA
                     GSVITYAKRYALSAIFGITSDQDDDGNEASKPNKTNQSQKPTNKTSKGTSFQTPKISN
                     IQVETYKSDLSDIAKATNQNVKELTKWLTDTLKVKSLEDLRTEQIVSTDDLINKLKKR
                     AGQKND"
     gene            complement(2964..3446)
                     /locus_tag="VH800_000769"
     CDS             complement(2964..3446)
                     /locus_tag="VH800_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEQ8361848.1"
                     /translation="MAYLYELEGIAAYLESLDLDDETFQNTLDSIDFQSDLENNIEYF
                     VKMLKNAQADVEMYKAEKEAFYKKQKQAEAKVEKYKETIRRAMELSQKKKVDAGMFKV
                     SLRKSKKVEILDETKIPLDYMQEKIEYKPMKSEISKALKSGIDISGVELIETESLQVK
                     "
     gene            complement(3468..3722)
                     /locus_tag="VH800_000770"
     CDS             complement(3468..3722)
                     /locus_tag="VH800_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361849.1"
                     /translation="MVGIRINGELVTFDSNFRDALIFTIDCLRGSEEPMLKQTYQTFK
                     DYTDEDLMDYIETEFDVWPELIVNRKIDSKWSTKQHILDD"
     gene            complement(3703..4056)
                     /locus_tag="VH800_000771"
     CDS             complement(3703..4056)
                     /locus_tag="VH800_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361850.1"
                     /translation="MVMPLDELEKRIFCYLPIGSNMMVNSKEICRTFDIKDPKTLRDI
                     IHGMVMKGYLIGSSRRKGGGYYLIDNDDERAEAISSLESQVRKEQKRINILKNGNLNE
                     FVEIANEVRNGWNQN"
     gene            complement(4197..4979)
                     /locus_tag="VH800_000772"
     CDS             complement(4197..4979)
                     /locus_tag="VH800_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ8361851.1"
                     /translation="MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTV
                     CPDCHREELDNQNALHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRADTAKH
                     KEMLYWAKTMANDWFSGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTD
                     LLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPAEIRKIYGERIASRIRKGCDKSHIMEFDGMEDERMKLWN"
     gene            complement(4966..5796)
                     /locus_tag="VH800_000773"
     CDS             complement(4966..5796)
                     /locus_tag="VH800_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEQ8361852.1"
                     /translation="MADNKKYYYLKLKENFFESDEAIILESMPDGYIYSNILLKLYLR
                     SLKNDGLLMFNNLIPYNAQMLATITRHQIGTVEKAIQIFRDLQLIEILDNGAIYMTNI
                     QNFVGKSSTDADRKRIEYAKAKQLGQISMKCAEKSPPEIEIELDKERELDKKIDINID
                     KELEVEEEIKDSSSAANVNNLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVK
                     EAITRAADNSKRSFGYVNSILRNWRQNGILTMVKVEEEQRQFQSRKSKQEEVSEYDTW
                     "
     gene            6010..6471
                     /locus_tag="VH800_000774"
     CDS             6010..6471
                     /locus_tag="VH800_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361853.1"
                     /translation="MIALVHSIYYNMVKIKLSDCYISRVDKGYDWMYDFSISNLSNVS
                     VIIKKIELYNKDGKLISDNGFNPFQKYEADMQNEADDYYGLSMPNYYMPLDYQWESSP
                     FKSDTEVYPSSRENFSYYLDEKPVKIKITTDKRIHQFRKYQLFFPHFDNNS"
     gene            6602..6811
                     /locus_tag="VH800_000775"
     CDS             6602..6811
                     /locus_tag="VH800_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361854.1"
                     /translation="MGPNYFHVQFKLGEKVSYNTPSAEGREVIPIKGAEVTKMIFADG
                     NELLSVIHNETVDVYASFPIVLEYH"
     gene            complement(6921..7121)
                     /locus_tag="VH800_000776"
     CDS             complement(6921..7121)
                     /locus_tag="VH800_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361855.1"
                     /translation="MTRFAIQRLREEKKMSQEELANKSGVSRTTISLIETDKSTTVKL
                     STLQKLAVALDVPIGYFFKHNV"
     gene            7195..7581
                     /locus_tag="VH800_000777"
     CDS             7195..7581
                     /locus_tag="VH800_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361856.1"
                     /translation="MFDYFKLYIIVLETFVETKPDDAYSLFDNLSLNSEFVKFSKDLD
                     KNIVISGTLEVIDNLLDDCLIKGKRRPTKDITFYFFDGVTTTGYLYLQSLKDNNFSSR
                     LKNVLKEEGIPLTPTSITRTIAKLTL"
     gene            complement(7570..7779)
                     /locus_tag="VH800_000778"
     CDS             complement(7570..7779)
                     /locus_tag="VH800_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361857.1"
                     /translation="MRPKKYPYSQKNYPAPKLHNVIETDNQFLIDDKRIHYVIEDSVK
                     TKTLGDGYVEVTLSIIAKSFTKSQG"
     gene            7833..8432
                     /locus_tag="VH800_000779"
     CDS             7833..8432
                     /locus_tag="VH800_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361858.1"
                     /translation="MDLLKNTNFLIPLISAIVSVSSIFISNWLGYRSQIRKLKFDEEK
                     EIYLTLYVPLIKWMNSQSFNNKSYYWLVAFPRYTTNAQDFLTGLLLKNFEKLPVSVAM
                     RYSEYTLNSATSLHFYRNTEYDYDYETFAKKASELFDLIIEQLLTEGTILSQKLSLPN
                     LSKSTLENFLADKKNYIGPRFLSLETHNKPLRPERPLPF"
     gene            complement(8462..8620)
                     /locus_tag="VH800_000780"
     CDS             complement(8462..8620)
                     /locus_tag="VH800_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361859.1"
                     /translation="MNWKKLMLGNLEHTFTSHDGKEKTSIEFEGGLLPALLVLGGITW
                     LAAWFITK"
     gene            8977..9801
                     /locus_tag="VH800_000781"
     CDS             8977..9801
                     /locus_tag="VH800_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8361860.1"
                     /translation="MKLGEIIKNFREEKKLSMDRFAEKSGLTKGYISMLEKNEHPKSK
                     KPIIPTEETLLKVAKGMGVDIDFVLSKLDSDQEIQINISPKNMLNMDNPSTPTTPKVE
                     LIPSTLQKINSTSSQLEHSRQIIVLDTAETLLEQQKEIKNNEDTIAELFSYNYYDHAA
                     SAGTGQYLNDVQVEKIELPVDYDADFVIPVYGDSMEPKYHSGDYVFVKLSVELTDGDI
                     GVFEYYGDAYIKQLLINDEGAFLHSLNSKYEDIPIDRDSDFRIIGEVVGSYSGNHS"
     gene            9837..10730
                     /locus_tag="VH800_000782"
     CDS             9837..10730
                     /locus_tag="VH800_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P63C domain-containing protein"
                     /protein_id="HEQ8361861.1"
                     /translation="MENEVLHATHEGKLVLDNTTLDVAVLNNGQRIITQAGVFKALDR
                     PSRGNTRVIGIPTFMDAKNLQPLISKDLRGVINKIEYRDLNGRIQLGFDANILPLVSD
                     LYLKAREIGAIKSEAQMRTAQKAEMLVRSLAKVGVTALVDEATGYQYERERFELQKIF
                     KAYISEELLKWQKMFPDDFYMEIFRLNGWSYDVQSIKRRPGVVGKWTNELIYKRLPDG
                     VLEELKRRTPKTKKGQYKARFFQTLTPDIGHPDLNAQIYKVLGIMRISSNWKDFKEKF
                     NVMTSREDGIIELDLEFDEDK"
     gene            10851..11939
                     /locus_tag="VH800_000783"
     CDS             10851..11939
                     /locus_tag="VH800_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ8361862.1"
                     /translation="MKIKSYKKENGETAYKFLLYAGYVNGKRKYIRREGFKTKQAARE
                     TLISLQAELDKPKSSMTFGALTDQWLKEYEKTVQCSTYLKTERNINKHILPKLDKVKI
                     GDINPLLIQRLTEEWCNDLKYGGKILGLVRNILNLAVRYGYINNNPALPITPPKIKRK
                     RKMNNNFYTLDQLKQFLELVEKTDNIEKIALFRLLAFTGIRKGELLALTWDDLNGNTL
                     SINKAVTRTQVGLEIDVTKTKSSDRLISLDDETLEILLELHETFPTSTLMFQSESGGI
                     MTPSLPRKWLLQIIKGTDLPQITIHGFRHTHASLLFESGLSLKQVQHRLGHGDLQTTM
                     NVYTHITQSAIDDIGTKFNQFVTNKQLD"
     gene            12302..12922
                     /locus_tag="VH800_000784"
     CDS             12302..12922
                     /locus_tag="VH800_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEQ8361863.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(13179..15443)
                     /gene="glgP"
                     /locus_tag="VH800_000785"
     CDS             complement(13179..15443)
                     /gene="glgP"
                     /locus_tag="VH800_000785"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEQ8361864.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLGRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(15478..16971)
                     /gene="malQ"
                     /locus_tag="VH800_000786"
     CDS             complement(15478..16971)
                     /gene="malQ"
                     /locus_tag="VH800_000786"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEQ8361865.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(17086..18105)
                     /locus_tag="VH800_000787"
     CDS             complement(17086..18105)
                     /locus_tag="VH800_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8361866.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            18351..19598
                     /locus_tag="VH800_000788"
     CDS             18351..19598
                     /locus_tag="VH800_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8361867.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKENDYLTKLQQFDKDIAATK"
     gene            19872..21233
                     /locus_tag="VH800_000789"
     CDS             19872..21233
                     /locus_tag="VH800_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8361868.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            21233..22069
                     /locus_tag="VH800_000790"
     CDS             21233..22069
                     /locus_tag="VH800_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8361869.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            22227..23024
                     /locus_tag="VH800_000791"
     CDS             22227..23024
                     /locus_tag="VH800_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8361870.1"
                     /translation="MTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHI
                     SNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLV
                     CLNEDSTEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAA
                     LKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLID
                     ESLDQFFVNSSQKLCCPRFSPKKGQVILETIEWAKKRQPDKKHNLLV"
     gene            complement(23140..23955)
                     /locus_tag="VH800_000792"
     CDS             complement(23140..23955)
                     /locus_tag="VH800_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEQ8361871.1"
                     /translation="MPDKKQFPISYISHCLSPRAMFASRAQFTWWQNLLIIVFLNALI
                     MIPVTLHYANMTTYPLERIVTKSLSPITDKTYQALTQGKIEKDTFQGQSLIRRDGELV
                     LAVLPTKVDLEQLASESTRQIIVTKKEWRFVTPDGKELRAHVRGQQQSLADLTTVKAV
                     KDFVNQQWYDSNKASVLGFLLLTFVLMVCVGTLIVIGLGAFFLTLTKRSRLFMIRNFS
                     EGLGLMVNCLAWPSLLAIALSFFIQDPVLIMNCQVFGTLLMLTWVFYKTQFRD"
     gene            complement(23977..24837)
                     /locus_tag="VH800_000793"
     CDS             complement(23977..24837)
                     /locus_tag="VH800_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8361872.1"
                     /translation="MRKTYVSISMKRKRFFTQLLTYLYLISLVIVILFPILVTVSSAF
                     RPGNTTAFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTGYA
                     YSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVRPMIAVQSLWAFMGPFGDF
                     MLAKFLLRAQENYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKNFV
                     SGLTSGGTKG"
     gene            complement(24834..26141)
                     /locus_tag="VH800_000794"
     CDS             complement(24834..26141)
                     /locus_tag="VH800_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8361873.1"
                     /translation="MVENQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLEL
                     LEIVVLGIPALTGLYSLGSVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKLVA
                     HQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVI
                     ANQSFIRGKRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVD
                     FGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADLYEAATVDGATVLQK
                     FRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYK
                     LTTQTSPQFSMASAVTLIISVIVISVSLITFKKFKAFDMEERS"
     gene            complement(26216..28351)
                     /locus_tag="VH800_000795"
     CDS             complement(26216..28351)
                     /locus_tag="VH800_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclomaltodextrin glucanotransferase"
                     /protein_id="HEQ8361874.1"
                     /translation="MRELHIKTYKLLTKSAVLLGLISFPLTVSAADNASVTNKADFST
                     DTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQGIIAKIKDGYLTDMGISAI
                     WISSPVENIDSIDPSNGSAAYHGYWAKDFFKTNQHFGTEADFQQLVKVAHQHHIKVVI
                     DFAPNHTSTAEKEGTTFKEDGALYKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNINPKVDQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFVFGEWFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKVL
                     ENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGVPNIYYGTEQ
                     YATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALAYGTTEQRWISDHVLVFE
                     RKFGNHVALVAINRDQTNGYTITNAKTALPQNSYKDKLEGLLGGQELIVGADGTISSF
                     ELGAGQVAVWTYEGEDKTPQLGDVDASVGIAGNKITISGQGFGNSKGQVTFGEISAEI
                     LSWSDTLITLKVPTVPANYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTV
                     PGEQLYLMGDVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKK
                     DSIGNVLWTSPETYSIKTGHEAQTITIKK"
     gene            complement(28377..30080)
                     /locus_tag="VH800_000796"
     CDS             complement(28377..30080)
                     /locus_tag="VH800_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEQ8361875.1"
                     /translation="MNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGP
                     KYGYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNRGDWEKGDSYVNMGW
                     LEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTPIFQSISNHKYDISDYYAIDPQF
                     GTKYDLQELIDLAHKMGIKIILDAVFNHASSDAVEFQDVLRYGKESKFFDWFMTHDEH
                     PSMDLVNYETFAGCNYMPKWNTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHD
                     FWRRFRQAVKAEKADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTS
                     KQLAEKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFIFMGI
                     PCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQQPALQEGAISID
                     YDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILTSNGVTKNKKQLLQDGYIVFS
                     N"
     gene            complement(30246..31505)
                     /locus_tag="VH800_000797"
     CDS             complement(30246..31505)
                     /locus_tag="VH800_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8361876.1"
                     /translation="MSWNWKKTSVLGTLSLASVLPLTACVSGGGKGVKETDGKTIVVS
                     VDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPTGASPDVFLAPFDRV
                     GGLGTEGQIAEVTLGNSKEFDDTVKKLVTIDGKTYGAPDVIETLVTYYNKDLVPQAPK
                     SFTELEVLQKDSKFAFASEPGKSVGFLAKWTDFYYGYGLIAGYGGYIFGDKGTKPSDL
                     GLGNDGTVEGLNYAKQWYGTWPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFK
                     DAGVNFGVMEIPTLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFY
                     DKTQEIPANLTARNYASKEGNELTKAVISQFESAQPMPNIPEMAEVWEPGANMFFNVA
                     SGKEEASKAAKEAAKTIKEAIEQKYAE"
     gene            complement(32120..33103)
                     /locus_tag="VH800_000798"
     CDS             complement(32120..33103)
                     /locus_tag="VH800_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8361877.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(33134..34384)
                     /gene="dltD"
                     /locus_tag="VH800_000799"
     CDS             complement(33134..34384)
                     /gene="dltD"
                     /locus_tag="VH800_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEQ8361878.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(34377..34616)
                     /gene="dltC"
                     /locus_tag="VH800_000800"
     CDS             complement(34377..34616)
                     /gene="dltC"
                     /locus_tag="VH800_000800"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEQ8361879.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(34634..35890)
                     /gene="dltB"
                     /locus_tag="VH800_000801"
     CDS             complement(34634..35890)
                     /gene="dltB"
                     /locus_tag="VH800_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEQ8361880.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYRENANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRHFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(35887..37425)
                     /gene="dltA"
                     /locus_tag="VH800_000802"
     CDS             complement(35887..37425)
                     /gene="dltA"
                     /locus_tag="VH800_000802"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEQ8361881.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(37437..37580)
                     /locus_tag="VH800_000803"
     CDS             complement(37437..37580)
                     /locus_tag="VH800_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEQ8361882.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT        11692 a         7437 c         6307 g        12168 t
ORIGIN      
        1 ctagcacgtt taagctgctt ttgtgtcctg cttagctgtg tacgtagtcc tgtgatttgc
       61 gactcgtaat attgtcgtgc gtcgcgatag ctaaaatacg acacggttac catcatccca
      121 aatattgcga ttgcaagaaa caatagtgct ttccaatcgt tttttaggac attcattatt
      181 ttattaaagt tatcacgtaa attttgcaac gcttcatcta tcgtcattct tccacctctg
      241 ccaaaatata agtcaaatct cttccgtaag gagaaagttg tacgacttga taaccaacaa
      301 ctgtcacttt tgcgtacttg tttttgtcga taaaatcgtt caggtggtct gttgcacttt
      361 tccattcgtc cttaacttca atatatctct tcattcttcc acgctttcga ttaaccaata
      421 ttcaatgaga cgctttgtat attcgagtgc tttttctaaa tcctgagtcg cattgccttt
      481 gtatctatgt cgtttaatgt atttatcaat gtgactttcc atgattgcga caaactggtc
      541 ccatgggtac gtcttatacc acgactcaat caaatcaatt tctccgtgat tataatgctt
      601 tggtttatgt actaattctt ctatcatcac tccacctctc tcaaataatt tactatcgtt
      661 ttacacacgc tctcatttgg caatattctg cgttctaaga gcgcttttaa ttgccaagta
      721 taaatgccta tcttatctgc taaaacgtca tcagacatct ttattttgca tctgtgagct
      781 attaacagct ctgatatatc gtaaggcaac agattatcgt aagatctagg tgtatattta
      841 atatcgttat gccactgtct gtgtcttttc atagacccat tctccgagct ctttctagtg
      901 cgtccgtgcg tttgattttt ttaacgagct taacgtcacc gtagttttta aacatccact
      961 tttcgtaaat cttgtcatcc tcatctgtct ttttttgttt aaggcggtaa gactgcttga
     1021 ttaacattat catttccttt gtcgtgtaaa ttcgttggaa ccactccaat acatcaggtg
     1081 gcggtaatct gtttagtttt ttatagtatt tgacagatct atagactctg tcagcttctt
     1141 ctttgtctgc gatggtaatg ttatcgtcta aaaacgcttt aattgacggc tccatttgtt
     1201 tgtaaaaatc atctactagt gtcataattc gtttattttt acctcgattc tgggatttgg
     1261 gctatacagc ttacgtgtag tgtgctcgac aatgatgttg tcatctgtcc acacaacctc
     1321 tgattttgat atgctgtcat atactgcttt ttcaaggttg tccaaatcgg gcttctttgg
     1381 cacatataag agctcattta tataatcctg atacttttgt ttagtcttat ctttggcacg
     1441 ctctgacggc tttttagaca ccaattctgg tgcttttaga taaaaagtaa catcaacttt
     1501 taaaccgtcg tcaaaataag gcccttcgta attgttttta acatagtctg tgacctgctt
     1561 ccgccatgcc atcatatctc catcctcgta agctccactc catctgctaa agcgtggacg
     1621 tttttgcggt tttggctcaa tcggtattat aaacttaacc actactcctc caattcgtct
     1681 tcgtatccta taaactctgc gtgtctgcca tctggtctcc tctttttatg agctggcgac
     1741 gctataaaaa ctattgtgtc agcggtaaca ccaagtcttt ctgctagctc atgctttgtg
     1801 ccaacatcta caaaagagtc tccgtcgtag accgcatata tcctttgtct atatctgtta
     1861 gccatatcat ttaaaacggc agatcatcgt ctgaaatatc cattgggttt gaattgccaa
     1921 acggttgact gttatcgttt tgcgaagagt tatcttgacc agattgttgc tggctatttc
     1981 gactttccaa catttggaaa ctctctgcaa caacttccgt cacatagaca cgttgttctt
     2041 gttggttttc gtagttacgt gtctgaatac gacccgtaac tccgatcaaa gcaccttttt
     2101 tagcccagtt ggctaaattt tcagcagact gtcgccagat aacacagtta atgaaatctg
     2161 cttctctctc cccgttttgc tctttaaatc tgcggtttac cgcaagtgtg aacgtagcta
     2221 cagctacttg actcgctgta tagcgaagct ctgcgtcctt ggtcatgcga ccaactagca
     2281 caatgttgtt aatcattttt ttgccctgct ctctttttta atttattaat caaatcatca
     2341 gtcgatacaa tctgttctgt gcgtaaatct tccagtgatt taacttttaa ggtatctgtt
     2401 agccattttg ttagctcttt gacattttga tttgtggctt ttgcaatatc gcttaaatca
     2461 gatttataag tctctacttg gatattgctg attttcgggg tttggaagct tgttcctttt
     2521 gacgttttat ttgttggttt ttgcgattga tttgttttgt tgggtttgct agcttcattg
     2581 ccgtcatcat cttgatcgct tgttatccca aaaattgctg atagtgcgta gcgttttgcg
     2641 taagtgataa ccgaaccagc gccttgtaca tcattttttg ttggtttaac acttaaaggt
     2701 ccgtattcca cccattcgcc actcgtgtgc atgactagcg ttgcgacatc gatataaccg
     2761 ttttctgcgt ttgttgttgg atcctgcgaa aaagatatcc cgttattagc aaaggctttt
     2821 gtaatcgctt ccgtcacgtt ttctagaggc acgtatttgc ttttgaaaaa ggggttgtct
     2881 ttatctttta gcggttgctt tacctctagc tgagctttac aaaaggcttt agcatattct
     2941 gttatacttt ctgatttcct catttacttt acctgcaaac tttctgtttc gattagttca
     3001 actccagata tatcaattcc agatttcaaa gctttcgaga tctcagattt cattggtttg
     3061 tattcaattt tttcttgcat gtaatcaaga ggaatttttg tttcgtccaa aatctctact
     3121 tttttgcttt ttcgcaaaga caccttaaac attccagcgt caactttttt cttttggctc
     3181 aattccattg cacgcctgat tgtctctttg tatttttcca cttttgcttc tgcttgcttt
     3241 tgctttttgt aaaaagcttc tttttcggct ttatacattt cgacgtcagc ttgagcattt
     3301 tttaacattt tgacaaaata ctcaatgtta ttttctaagt ctgattgaaa atcaatgctg
     3361 tcaagcgtat tttgaaaggt ttcgtcgtct aaatctaaac tttccagata agcggcgatt
     3421 ccctcaagtt catataaata agccatgtta tttcctcttt ctgtatttta atcatccaaa
     3481 atgtgttgtt tagtggacca cttgctgtca atcttgcgat taacgattag ctctggccat
     3541 acatcaaatt ctgtctcgat gtagtccatc aagtcttcgt ctgtgtagtc tttaaaggtt
     3601 tgataagtct gttttagcat aggttcttcg ctgcctctaa gacagtcaat cgtaaagata
     3661 agcgcatctc taaaattgct atcaaaggtt acgagctcac cgttaattct gattccaacc
     3721 atttcgcacc tcgttagcta tttctacgaa ttcgttcaag tttccgtttt ttaaaatgtt
     3781 tatccgcttt tgttcttttc taacttgact ttcaagtgag ctgatagctt ctgcacgctc
     3841 atcatcgttg tcaattagat agtaccctcc gccttttcga cggctagaac ctatcaaata
     3901 gcctttcatt accattccgt ggataatgtc tctcaaggtt ttcgggtctt tgatgtcaaa
     3961 tgttcgacaa atttcctttg aattaaccat catgttactt cctatcggca aataacaaaa
     4021 tattcttttt tctaactcat ctagtggcat taccatatta aatctctcct aaaacgtgac
     4081 ttttgagcac tctctccacg ctctcaattc ttcaattttc tttgttcgga catcttcatc
     4141 tagcgccatg atttttgccg catgttcctc ggatagcccg aaaaatgttg ttagtgtcaa
     4201 ttccatagct tcatcctttc gtcctccatg ccatcaaatt ccatgatatg acttttgtcg
     4261 cagccttttc tgatacggga tgcaattctc tctccataaa tttttctaat ttcggcaggt
     4321 gtcagattgg tagtaatgat tgtgtttgtg cgcttgttaa gcaagctgta aataatgctt
     4381 gtggaccagt cactaacttt ttcggcacct agatcatcta gcaccagata atcgacatct
     4441 tttagcttat ccatccaaaa tgcttccttg ctaaagtctc gctttatctc tgacagtaag
     4501 tcagtgacat ttacaagcaa gcctaatttt ttcgttttat cagacaatcc cctaatgatg
     4561 ctataagcta aatgactttt gcctcgtcct gctttgccag tcatgatgat gtttccctta
     4621 ccaccactaa accaatcgtt agccattgtc tttgcccaat aaagcatctc tttgtgttta
     4681 gccgtatcag ccctaaaatt gtcaaatgat gcattttcca actcgtcgtc cataattgat
     4741 aattttttga gatagtacag tcgcttgttt tcaagctctc tctcatattg cttttggacg
     4801 tgcaaagcgt tttgattgtc taattcttct ctgtgacaat ctggacatac tgtcaaacca
     4861 gtcttgagga ctgtgatgta tctacaacca tgtttttcac agacagcatc ttctttcttg
     4921 gtgttttgtt gataagatat agcgatttta gcaagtgcgt cttcgtcacc aagtatcata
     4981 ttccgatacc tcttcttgtt tagattttct agattggaat tgcctttgtt cttcttcaac
     5041 tttaaccatc gtaaggattc cgttttgtct ccaatttcgc aatatagagt taacgtatcc
     5101 aaaagaacgt ttagaattgt cagcagctct cgttatcgct tccttaacaa catccacttc
     5161 catttttgtg atggtgatat agtctgacaa ctgttcaaac tgattcggag ataagatgcc
     5221 aatttcttgt tgaaaataat cagatataat ttttaagtta tttacattag cagcagaaga
     5281 tgaatctttt atctcttctt ctacttctaa ctctttatct atatttatat ctatcttttt
     5341 atctaactct ctctctttat ctaactctat ctctatctct ggtggagatt tctccgcaca
     5401 tttcatggag atttgtccaa gttgtttagc ctttgcatat tcaattcttt ttctgtcagc
     5461 atctgtgctt gatttaccaa caaaattttg aatatttgtc atatatatcg caccgttatc
     5521 gagaatttcg attaactgta ggtctctaaa aatttgaata gccttttcga cagtgccaat
     5581 ctgatgcctt gtaattgtgg caagcatttg tgcgttgtaa ggaataagat tgttaaacat
     5641 taataagcca tcatttttta aacttcttag atataacttg agcaaaatat tgctatagat
     5701 atagccgtca ggcatacttt ctaaaatgat tgcttcatca ctttcaaaga aattttcctt
     5761 taattttaag taataatact ttttgttatc tgccatttat ctcccttctt caaaaatagc
     5821 tttcacattt cttatctttt aacgtctcaa taattccatc taaaacatct gatcggtttt
     5881 taagctcatt gtactctttg acagatattg tgataaaatc tttgttatct tttgtagtat
     5941 cgctatatcc gagcaggtaa gcgaccgata catcaaaatg atctgctagt aattgcgcta
     6001 attgttgctg tgattgctct tgttcactct atctactaca acatggttaa gataaaatta
     6061 tctgattgtt acatttcaag agtagataaa ggttacgatt ggatgtatga ttttagtatc
     6121 agtaacttat cgaatgtttc agtcattatt aaaaaaattg aactttacaa caaagatgga
     6181 aaactaataa gcgataatgg cttcaatccc tttcaaaaat acgaagctga catgcagaat
     6241 gaagctgatg attattatgg attgtcaatg ccgaattatt atatgccatt agattaccaa
     6301 tgggagtcat cgccatttaa gtcagatact gaagtatatc catctagtcg agaaaatttc
     6361 tcttactatt tagatgaaaa gccagttaaa atcaaaatca caactgataa gcgtattcat
     6421 caattccgaa aatatcagtt attctttccc cattttgaca ataatagtta agatagcgat
     6481 attcgttaat aaaattaaga taagtgctgc cgttagtagc attttttctt ttctcctttt
     6541 attagttttg ttcctcctgc gtgctataat aaagctatca ttacgaaagg aggaaaaaag
     6601 catgggtcct aattattttc atgtccaatt taagttaggc gaaaaagtat cgtacaacac
     6661 gccttcagca gaaggaagag aagtcatccc tatcaaaggt gctgaagtta cgaaaatgat
     6721 tttcgccgat ggtaacgaat tgttaagcgt tattcacaac gaaaccgttg acgtttacgc
     6781 tagcttccca attgttcttg agtatcatta attcgttatt tctaaaccag caatcgcccg
     6841 ctactgcgtt tgttggtttt tcttttccgt aaaaaattcg atttgcttgc atagtgtcct
     6901 ttccagtttt gtttaacacg ttaaacatta tgtttaaaaa aatatccaat aggtacgtct
     6961 aaagcgactg ccaatttttg aagagtgctt agcttaaccg tagtagattt atcggtttca
     7021 ataagagata tagtagttcg tgagactcca gatttattgg ctagctcttc ttgagacatt
     7081 ttcttttctt cacgcaatct ttgaattgca aacctcgtca ttcccccacc tcctttctat
     7141 ctgtttttag ttcctccaat ctgctataat atgggcagaa aggaggtgaa tgtgatgttt
     7201 gactatttca aactttatat aattgtcttg gaaaccttcg tggaaaccaa accagacgac
     7261 gcttatagct tatttgataa tctaagtctt aacagtgaat ttgtaaaatt ctctaaagac
     7321 ttagataaaa acattgtaat atcaggcact ttagaagtaa ttgataattt acttgatgat
     7381 tgcttgataa aaggaaaacg tcgcccaaca aaagatatta ctttctattt tttcgatggc
     7441 gtaacaacaa ctggttactt atatcttcaa agtcttaaag ataataattt ttcgagccgt
     7501 ttaaagaatg tccttaaaga agaaggtatc cctcttacac caacttctat cacaaggact
     7561 atcgccaaac taaccttgtg attttgtaaa actcttggca attatggaaa gtgttacttc
     7621 aacatagcca tcgccaaggg tttttgtctt tacagaatct tcaataacat aatgaatcct
     7681 tttatcatct attaagaact gattatcggt ttcaatgacg ttatgaagct tcggcgctgg
     7741 ataatttttt tggctatacg gatatttttt ggggcgcatc tattccaccc cctttctgtg
     7801 gtataattta aataaaatga ttggagaaaa tcatggattt attgaaaaat accaattttt
     7861 taattccgtt aatttcagca atagtctctg tttcttctat ttttataagc aattggcttg
     7921 gttatagaag tcaaatcagg aaattaaaat ttgatgaaga aaaagaaata tacctaaccc
     7981 tctatgtacc gttaataaag tggatgaatt cgcaatcatt caataacaaa agttattatt
     8041 ggctagtggc gttccctaga tatacaacaa atgcacaaga ttttctgaca ggcttgttgt
     8101 taaaaaattt tgaaaaatta ccagtatcag ttgctatgag atactctgaa tacaccctaa
     8161 attctgcaac ctctttacat ttttatcgta acaccgaata cgattatgat tatgaaacat
     8221 ttgccaaaaa agcatctgaa ttatttgatc tcattattga acaattgcta acagaaggga
     8281 caatattatc ccaaaagcta agcttaccaa acttatccaa atccacttta gagaactttt
     8341 tggcggacaa gaaaaactat atcggtccca gatttttatc actagaaacc cataacaaac
     8401 ccctaagacc tgaaagacca ctgccatttt aactcccccc tttccgcccc ttgtgggctt
     8461 tttattttgt aataaaccaa gctgctaacc aagtgatacc acctaacacc aacagcgctg
     8521 gcaataagcc accttcaaat tcgatgcttg ttttttcttt gccatcatga ctagtaaacg
     8581 tgtgttctaa gttgccaagc attagctttt tccaattcat gcaacctctc ctttcattct
     8641 tgcggagata cagccaatgt gctaaactaa acttaccccg ttagggggag aggacttctt
     8701 agccctctaa ttatcctcac cactctattg agtagtgaat cttaagctta aaccaaagaa
     8761 tcttgatttc gacttctagt tctttgcgtt taggcttttt gtttagccta gatttcatca
     8821 gctgtacctc ctttcgtttt gcttaatccc ttaagcttga ttatagttta acacgttaaa
     8881 cattcattgt caagcgtgtt aaacaaaaat attgaattat tttttgttgt gttgtataat
     8941 gtattaaaca atcattctag gaagaggttt ttaacattga aattagggga aataataaaa
     9001 aatttcaggg aagaaaaaaa gttatcaatg gataggtttg ctgaaaaatc tggtcttact
     9061 aaggggtata tttcaatgct tgaaaaaaac gagcatccga aatctaaaaa accaattatc
     9121 cctacagaag aaactttgtt aaaagtagca aaagggatgg gggttgatat tgattttgtt
     9181 ttgagtaaat tagattccga tcaagaaata cagattaata tttctcctaa gaatatgtta
     9241 aatatggata atccctccac tcccaccacc ccaaaagtcg aacttatccc atctactcta
     9301 caaaaaataa actctacttc ttctcaacta gaacacagta gacagataat tgttttagat
     9361 acagctgaga ctttattgga acaacagaaa gaaattaaaa acaacgaaga tactattgcc
     9421 gaattatttt cttacaacta ctacgaccac gcagcttcag ctggtacagg tcagtatcta
     9481 aatgatgtac aagtagaaaa aattgagtta ccagtcgatt atgacgcaga ctttgttatc
     9541 cctgtttatg gtgattccat ggaaccgaag tatcactctg gggattatgt atttgttaag
     9601 ctatccgtag agcttacaga tggcgatata ggcgtctttg aatactatgg tgacgcttat
     9661 atcaaacagc tacttataaa tgacgagggg gcatttctgc acagtttaaa tagcaagtat
     9721 gaagatatac cgatagatag agatagtgat tttaggatta ttggtgaagt tgttggaagt
     9781 tattcgggaa atcatagcta acgaagctac ggttgtgaat gagtttagga gaaaatatgg
     9841 aaaatgaagt tttacatgca actcacgagg gtaaattagt cttagataat acaactcttg
     9901 atgtagcagt tttaaataac ggtcagcgaa tcatcaccca agctggtgtt tttaaagcat
     9961 tggacagacc tagtagaggc aatacccgtg tgatcggaat acctactttt atggatgcaa
    10021 aaaaccttca accattgata tcaaaggatt taaggggtgt gatcaacaaa attgaatata
    10081 gggatttaaa tggtaggatt caattaggtt ttgatgctaa cattttaccg ctagtatcag
    10141 atttatattt aaaagctaga gaaattggag ctatcaaatc agaagctcag atgagaactg
    10201 cacaaaaagc ggaaatgtta gttcgctcac ttgcgaaagt tggtgttact gctttagtag
    10261 atgaagctac tggttatcaa tatgagagag aacgttttga gcttcaaaaa atatttaaag
    10321 catatattag tgaagaattg ctaaaatggc aaaagatgtt tccagatgat ttttatatgg
    10381 aaatttttag attgaacggg tggagctacg atgttcaatc aattaaaagg cgtccaggtg
    10441 ttgttggtaa atggacaaac gaattgattt ataaaagact gcctgatgga gtgttagaag
    10501 aattaaaaag aagaactcca aaaacaaaga aaggtcaata taaagctaga tttttccaaa
    10561 ctttaacacc agatatagga catcctgatt taaacgctca aatttataaa gttcttggga
    10621 ttatgagaat ttcatctaac tggaaagatt tcaaagagaa atttaatgtt atgacatcta
    10681 gagaagacgg tataattgaa ttagatttag aatttgatga agacaaataa aaaaagcccc
    10741 acgctctcaa agtttggcga ctctgagcgt gaggcaagac agtataagaa acaaccatta
    10801 aaaaggtcat tttcttgtac ctattttatc aaattgaaag atggtatgca atgaaaatta
    10861 aatcatataa aaaggaaaat ggtgaaactg cttataaatt tcttttgtat gccggttatg
    10921 ttaatggaaa aagaaaatat attaggcgag aaggtttcaa aactaagcag gctgcaaggg
    10981 aaaccttaat tagtttacaa gctgaacttg ataaacctaa atcaagtatg acatttggag
    11041 cattgacaga tcaatggcta aaggaatatg aaaaaaccgt tcagtgcagt acctacttaa
    11101 aaacagaaag aaatattaat aaacatattt tgccaaaact tgataaagtg aagattggag
    11161 acatcaaccc actacttatc cagcggctta ctgaagaatg gtgcaacgat ttaaaatatg
    11221 gaggaaaaat tcttgggctt gttaggaata tcttaaatct agctgttaga tacggatata
    11281 tcaataacaa tccagctttg ccaattacac ctccaaaaat aaaaaggaaa agaaaaatga
    11341 ataataattt ttatacactt gatcaactta aacaattcct tgaactagtt gaaaaaactg
    11401 acaacattga aaaaatagcc ttgtttagat tattagcatt tactggaata cgaaaagggg
    11461 agcttctggc actaacttgg gatgatttga atggtaatac tctatcaatt aataaagctg
    11521 tcacacgtac tcaagttgga ctagaaatag atgttacgaa gacaaaatcg agcgatagat
    11581 taatcagctt agatgatgaa actttggaaa ttttactaga acttcatgaa acttttccta
    11641 cttctactct tatgttccaa tctgaatcag gtggaattat gacgccaagt ttaccacgaa
    11701 aatggctatt gcaaattatc aaagggacag acttaccaca aatcacaatt catggtttca
    11761 ggcacactca tgcaagctta cttttcgaat caggtctatc cttgaaacag gtgcaacata
    11821 gattagggca tggagattta cagacaacta tgaacgtata tactcacatc acgcaatcgg
    11881 caattgatga cattggaact aaattcaatc aatttgttac taacaagcaa ctagattgac
    11941 aactaattct caacaaacgt taatttaaca acattcaagt aactcccacc agctccatca
    12001 atgcttaccg taagtaatca taacttacta aaaccttgtt acatcaaggt tttttctttt
    12061 tgtcttgttc atgagtttcc gttatcccta tagccatacc atcacgctta ccgatactcc
    12121 atcaatacca ctcaaaacct tgtcatatca gatctttttg accatttttt tcatgaatat
    12181 ctaaaaaaaa gaatcaaaat agtactaaat tccccatagc gcatgcgcta tggggaatca
    12241 tagctatatc ttgtttataa tttatgatat aatacagcaa aaatagttta ggaaataaca
    12301 tatgacaaaa aaacacttac taacacttct tctcatctct ttttttacta gctttttggt
    12361 agcttgttca acaacgaaag ataaagagcc tcaaccgtct gattcagaaa tcattactcc
    12421 ccgactacac caagccgctc atcaagataa acgcgctaac tttgaaaaaa ttaaacttgc
    12481 gactgttgat tcctcattta caggagggac aagccttgaa gaacttattt cactctttgg
    12541 agagcctagc caacatgatc caaaaacagc aggcgaagta acaatcgacg cttatacttg
    12601 gcagtttgat caagttactc tcactgttaa tctttatcaa aatagtagta ttgttaaaac
    12661 catctctaat tttacctttg caagagagtt aggcttatcg caaaaggaat accaacaatt
    12721 acaaaaagga atgtcttatg aagacgttaa aaagatctta acagaacctg ataattatag
    12781 ccaagcgtca tctagtgatc atcaaacttt gcaagcgatt tgggttagtg gcttaaagac
    12841 agatacaagc ggagctaata tttctctcgt ttttgaaaat aatcagttaa cagaaatgtc
    12901 tcaggtagga cttgaagaat aaaaaatgag taatatattt tgctaaaaag attgatttcg
    12961 gtgtacatcg aaatcaatct ttttatatca ttttaataaa aaactttagt gtagtttctt
    13021 ataattacct ccatagatcg ctaaacagac ttgctttacg cttaatgtaa taattaacct
    13081 aagtctgaag taaaatcata agacagcaga aactactgtc ttataattta gtttaagcat
    13141 gttacggtac cgctacccca cattgcaatt attatttttt atcgtgaatg ccaaatatct
    13201 tcgttatact gctcaatggt acggtcagat gagaagaatc cagcttttgc gatgttatgg
    13261 accacttttg tcatccataa atcttggtct tcatagtctg ctaacatttt ttctttcact
    13321 tcaatgtact cttcaaggtc aatcaaagtc atgaaccagt cttttgaaat caattcttta
    13381 taaagacgac caagacgttc ttcgttgcca aatgctagca attctggact gataataaag
    13441 ttcactgctg ctttaatagc agggtggtta tcatagtaat cttttgctac ataagaagca
    13501 gtcgcataaa ggttgatgat ggtgtcagaa tctttaccaa aggtatagat attctccatg
    13561 cctgcaagct cagcgatttc tacgttagca ccgtccattg taccaagtgt taaagcaccg
    13621 ttaagcatga atttcatatt accagttcca gaagcttctt tggatgctag tgaaatttgc
    13681 tcagaaatat cagttgctgg aatcaagtgc tctgctactg tcacgttgta attttcaact
    13741 agatgcacat taaggtatgg gcttacttca gggtcattgt taatcaattc agacaagcaa
    13801 aggatcaagt gaatgatgtc ttgcgcaata atgtaagcag gcgctgcttt acctccaaag
    13861 ataacagtga ttttacgttt tggaaggttg ccttttttaa tttccaaata tttgtgaatc
    13921 acgtaaagag cattcatctg ttgacgtttg tactcgtgga aacgtttgat ttgggtatca
    13981 ataatagaat gttcatcaag ctcaatgtct ttattgtctt taaggtaacg tttaagagct
    14041 aatttgttgt tgaatttgat ttcagccaat ttagcatgaa cagctttgtc atctgcaaag
    14101 gccatcaatt tttctaattt tgttgcgtca gtcaagtact catcgccaat aagttcttta
    14161 atgtaatcag ccaagtcttg gttagcaaat tctagccaac gacggaaagt aatcccgttg
    14221 gttttgttgt tgaatttttc tgggtaaagg tcatagaaag cttttaattc gctgtttttc
    14281 aagatttctg tgtggagtgc tgctacccca ttgacacttg ttgcaaaatg aatatccata
    14341 tgggccatgt gcacacgacc tgattcgtca ataatttgaa cagctggatc agacacttct
    14401 gaacgaacaa gagcatccaa tttttcaatg atggttacca agtgtggcac tacttcgttt
    14461 aagtaagcag ttggccattt ttcaagggct tctgcaagaa tagtgtggtt agtgtaacca
    14521 accatatttt tcacaacagc taccgcttca tcaaagtcaa agccatgttt ttcagtcaag
    14581 agacgaatta attctgggat gaccattgat ggatgcgtgt cattaatttg cacgtaagcg
    14641 tagtctgcaa ggtcatgaag gtttgaacca cgttcgatag cttcatcaat gattaattgc
    14701 gctgcatttg acaccataaa gtactgttgg taaatacgga gcaattcccc atttttgtca
    14761 gaatcgtctg ggtagaggaa caaggtcaag tttttagcaa tttgcgtttt atcaaaagaa
    14821 atgccgtctt tgattaaccc gtaatcaacg ccctcgatat caaacaagtt aaggtagttt
    14881 ttagtgtcgc gtttgtaacc caaaacatca atacgatcaa gacgagattt caaggtgaag
    14941 ttcttaaaag gcacatcgta agaaatgtct gttggaacca accatgagtc atcttcaatc
    15001 cagaagtttg gctcagcttc ttgctcattg tgtttgaaga cttgcttaaa caacccacaa
    15061 tgatagttta aaccaacccc ttcaccatta atcccaagag atgcaataga gtcaataaaa
    15121 catgaagcaa ggcgtcctaa accaccatta cctagtgatg gttctaattc aacatcttcg
    15181 acttctgcga tagacttgcc agcagctgcc aattcttctt tgatgtcctt gtaaattcct
    15241 aggttaatca ggttgtttga tagtaattta ccaatcaaaa actctgctga gatatagtaa
    15301 actttgcgtt tagcagaatt tttagccttg tggctagctt cttctttgac aaagtttaat
    15361 aatgatagat aaatctcttc attgctggct tgcgtaagtg attttcctag tttagtttca
    15421 acatattctg taaagcgtgt catgtcttcc tcttttcaat aatgtaacat ttaaatatta
    15481 tcttgcgcga ccataaagat ctgttaaata aataaggtaa tctttgtgat cttggttcaa
    15541 ttcaccgtca agcatacgcc attgccaatt acctccaatt gtatttggca tattcatacg
    15601 actcttacca tctttatcta ataaatcttg gatgcaaaga atggctgtat cacaaacaga
    15661 agcaaagatt gttcttagca tggcttttgt aatactttca tctgcatgtt tgtgaagata
    15721 gttatttaca aagtgtactt gttcttcact aagattgtca taccatccgt taaccacctc
    15781 gttatcatga gtccctgtgt aagcgacaca attacggtca tagtaatgtg gtaaatctat
    15841 actttgactc gttatatcaa ataaaccaaa ttctaatatc ttcatgccag gaaagcctgt
    15901 tgatgctaat agctgctctg ctttttcatc aatataaccc aggttttctg cgatgatagg
    15961 gagctctcct aaggcctcac gaaccgcaga aaataatgct atacctgggg ctgaggccca
    16021 atggccattt ctagcagttt tatcaccagc aggaatttcc caaaaatctg agaagccttt
    16081 aaaatgatcg attcttagct gatcatatag tttgaaactt tcttgaatac gataaatcca
    16141 ccatgcaaaa ttagactttt catgagcaga ccaattgtag gttggatttc cccacagctg
    16201 accatcttca ctaaagccat ctgctggtac acctgcaata aacaatggct ttttatcact
    16261 atctacttta aatagctcag gcatcgtcca aacttctaca ctgtccgcag aaacataaat
    16321 aggcatatca ccaataattt ctatcccttt atggttagcg taagttttca aggctgacca
    16381 ttgttggtaa aagaagtatt gacagacttt atgataggta atcttttttg caagtaactc
    16441 acggtaatta ttaagtgagt cttcttggcg tttaatgaca gtttcgtcgt cccaatcttg
    16501 taaggcttta ttgttaaaat attcttttaa agccataaat tcagcaaaat cagttaacca
    16561 gctagaagct gtttcaaaag cttctaattt acacacattt tcttgttcag caacaaaagc
    16621 tctcactgct ttttctaaaa gtggacgtct aacttgaaaa agctgagcat agtctactgc
    16681 ttcaggattt gtgccgaatg taatatcaca caaatctgct gcttctaaaa gttcatcatc
    16741 tactagcaat tcaaaatcaa tgaaatgtgt gttcccagca atagctgaaa atgactgata
    16801 aggagaatct ccaaaactcg tcgttgttaa aggcagaatt tgccaatagg tttgtttcgt
    16861 ctctgctaga aaatcaacaa attcaaaagc tgattttcca aaagtgccta tcccaaattt
    16921 cccaggcagg gaactaatat gcattaagat accgcttgca cgtttgttca tgatttttct
    16981 ccttgtgaaa tctattcatg atgagattat aacgcaagcg cttgcgtaag tcaaccagtt
    17041 tcctaaaaaa agtaacattc cttaaaaatg ctactttttt tgttcttaat gactaatatc
    17101 acggacgctt tctctttgtt ttaaactaaa aggaacaaaa atagtctgac taagattctg
    17161 ttcattggaa ttgataatat caagtaattg cttaaaagac atttttccaa gattttcaac
    17221 atttatatca aatgtcgtta aataagggtg aattaattta gcgtaattag aattattaaa
    17281 agtgataatt gacatatcat ctggcacttt tatatcataa aaagataata actgtaccat
    17341 acgaatagcc agaacatcac caacaacaac caaggcagtt gctttaaagg aagatatagt
    17401 ttccatcaat atttctacgc taacaggatc cttacgatca aataacagca ttggctttgt
    17461 ttttaaagat cgcttaaaac aacccttcaa atagccaaga taacgctcag aagttacttc
    17521 tgatagtaaa tcatctgtta taaataatat gttgtgatgg cctttttgat aaaggtgttc
    17581 tactgctgtt ttagccatta gctgattatc attatcaata taagtggttt tattagtgtc
    17641 accttgtgga gcacctacaa tgacaaatgg taagttattt gtcatcaaat attttttgac
    17701 aggatcatct tgatcagaat aaagaataat aaaaccatca actcgttttt gaagatgcat
    17761 cagtttcact tgctctatca ggtcatcaag agatatacct gtagcaatcg acacagtaaa
    17821 atgagattct ttagcttcgt tagtaatagt cgacaaaatt tccataaaga aaggttcact
    17881 taatctatcg ctagttgtaa taggaggaaa aacaagtcct atattgtgtg tcaaaccact
    17941 cgctagaatc tgtgctgcga catttggaac atatcccaaa tctgccatcg cttttctaac
    18001 cttctctttt gtcttcatag aaatagatcg attatctttt aataccctac tcaccgtcga
    18061 agggttaaca cctgcctttt gagcgacatc ttttattgtt accatattaa cctcgttact
    18121 atatttacca aagataaacc ttatcatggg tttgtcatgt atttcgtttc cattatacaa
    18181 ttatctttca aaaaatcaac ttcaatcaag attcccttgt cattttaact caaattctct
    18241 aaactatttt tttaaaaaaa acgacctttt ttttaaaaaa aggcttgact ttttctgcaa
    18301 gcggttgcat aatattaagt gtaagaaata tatcttagga ggaaatagct atgaaatcat
    18361 ggcaaaaagt tatcgtcggc ggagcaagtt tgacacttgc aagtaccttg ttagtgggat
    18421 gtggatcagg ttcaaaagat aaaaaggaag ctggcgctga ctcaaagact attaaacttt
    18481 gggtaccgac tggctctaaa aaatcatatg cagataccat tgcaaaattt gaaaaagatt
    18541 ctggttacac cgttaaagtg gttgaatcag aagatccaaa agcacaagaa aaaatcaaaa
    18601 aagatgcctc aactgctgcc gatgtctttt cacttcctca tgatcaactt ggtcaacttg
    18661 tagaatctgg tactattcaa gaagttccag aaaagtacaa taaagaaatt gctgctactt
    18721 ctactgatca ggcgctcgtc ggtgcacagt acaaagggaa aacatatgct ttcccatttg
    18781 gtattgaatc acaagttctt ttctacaata aatcaaaatt agctgctgaa gacgttactt
    18841 catatgatac aattactaca aaagcaactt ttggtggtac ctttaaacaa gctaacactt
    18901 acgctactgg tccattattc atgtcagttg gtaacacttt atttggggaa aacggtgaag
    18961 atgtaaaagg tactaactgg ggcaatgaaa aaggcgctgc tgttcttaaa tggatcgcag
    19021 accaagcttc aaataaaggt tttgttagct tagatgctaa caacgttatg tctaaatttg
    19081 gtgacggttc agtagcttcc tttgaatcag gaccgtggga ctatgaagct gctcaaaaag
    19141 ctatcggtaa agaaaacctt ggtgttgcta tttatccaaa agtaactatt ggaggcgaaa
    19201 cggttcaaca aaaagcattc ttgggtgtaa aactttacgc agtcaaccaa gcaccagcta
    19261 aaggtgatac aaaacgtatc gcagctagct acaaattggc atcctacttg actaatgctg
    19321 aaagccaaga aaaccaattc aaaactcgta acattgtccc agccaacaaa gaagttcaat
    19381 cttcagaagc tgttcaatca aacgaacttg ctaaaaccgt tatcactatg ggttcttctt
    19441 cagactacac tgtcgtaatg ccaaaactta gccaaatggg cacattctgg actgaaagtg
    19501 ctgctattct tagtgatgcc ttcaacggta aaatcaaaga aaacgactac cttactaagt
    19561 tgcaacaatt cgacaaagat atcgctgcaa caaaataata tgatctcatg tcatcactgc
    19621 tatactaaaa caagcacaag gtaagtactt ctaaaaagtt ctttccactt accttatgaa
    19681 gagtggaact aggctccatc acattttatt caagcttagt ctcactctta cttgtttttg
    19741 ttttactagt agcttagtgc tacttaaatt tttaactctt taaaagttta cgtaacactt
    19801 agctatttca tcctaacaag agattgaatc tgaactacca ctctagtatc ctaaaataaa
    19861 ggagaatcta tatgactcag tcaaacttga caccaaatat atctgtaata gaagccttaa
    19921 aaagaggcag ttgggatatt aaactttcga gtattatcat gggatttgcc aactttgcta
    19981 acaaacagtt tatcaaagga atcttatttt taataagtga acttatcttt ctagtagctt
    20041 ttgtctccca aatcatccct gctatccgtg gccttgtcac tcttggtact caaactcagg
    20101 gaatgactac aaaaactatt gatgggatta acatccaagt tgctgttgat ggcgataact
    20161 ctatgttaat gcttattttt ggtttagcat cactcatttt ctgcctagtc tttgcttaca
    20221 tttactggtg taatctcaaa agtgctcgta acctttatct tttcaaacaa aaaggtcaga
    20281 agataccaag cttcaaagaa gatcttgcca cacttacaaa tggtcgcttt catatgactt
    20341 taatggctat cccactgatt ggtgtgcttt tattcaccat tcttcctttg atttacatga
    20401 tctgtttggc ctttaccaat tttgatcata atcacttgcc tccaaaatct ttatttgatt
    20461 gggtgggact tgctaacttt ggaaatgttt taagcggccg tatggcagga accttttttc
    20521 ctatcttctc atggactttg atttgggctg tttttgccac agtaactaat ttcttctttg
    20581 gtattattct tgctttgtta atcaatacca aaggattaaa gtggaaaaaa atgtggcgaa
    20641 ccatctttgt tatcaccatt gcagttccac aattcatctc attattgatt atgcggaact
    20701 tactcaatga cgaaggccca ctaaatgctc ttctcaataa aatcggcttg attaatggct
    20761 cactgccatt tttatctgat cctctttggg caaaattctc aatcattttt gtcaacatgt
    20821 ggatcggtat tccatttacc atgctgattg cgactggtat tatcatgaac cttccaagtg
    20881 aacaaattga ggctgctgaa attgatggcg ctagcaaatt ccaagtcttc aagtctatca
    20941 cgttccctca aattctcttg atcatgacac caaacttgat tcaacaattt atcggaaata
    21001 tcaataactt taacgtcatt tacctcctta ctggtggtgg tccaacaaat tcagaatact
    21061 atcaggcagg aacaacagac ttgctggtca cttggcttta taaattaacc gtcacagctg
    21121 ctgactacaa tttagcttct gttatcggta tcttaatctt tacagtttca gctatcttta
    21181 gcttacttgc ttatacaagg acagcatcct acaaggaagg agcggctaaa taatgaaaaa
    21241 caaacgtcga tttcaacttg gacttgttta tgctacttta atcatcctct caatcatttg
    21301 gctcttccca atcgcttggg ttattcttac tagcttccgt agcgaaggaa ctgcttacgt
    21361 caattatttt attcctaaga cttttacatt aaatcactac attaatcttt ttactaatga
    21421 aacctttcct tttggaaaat ggtttatgaa tactcttatt gtagccactt ttacatgtat
    21481 tatttcaacc ttcataactg ttgccatagc ctactctctt agccgaatta agtttaagtt
    21541 tcgcaatggc tttttaaaac tagcccttat tttaaatatg ttccctggtt tcatgagcat
    21601 gattgccatc tactatatct taaaggcctt aggtttgacg caaaccctaa cagcacttgt
    21661 ccttgtttat tcctcaggtg cagcccttgg tttttacatt gcaaaaggat tttttgatac
    21721 cattccttat tcacttgatg aatcagctat gattgatggc gctactcgta tggatatttt
    21781 ctttaaaata acccttcctt tagcaaaacc aatcattgtc tatactgccc ttcttgcttt
    21841 tatggggcct tggattgact ttatctttgc acaagttatt ttaggtgatg ctacaagtaa
    21901 atataccgtt gctattggac tattttcaat gcttcagcca gataccatta acaactggtt
    21961 tatggccttc actgctggtt ctgtcttaat tgccgtccca atcactctcc tcttcatgtt
    22021 tatgcaaaaa tactatgttg aaggcatcac aggtggttct gttaaataag ttacaacata
    22081 ccaaaccttc taagggcaag ccctttagga ggtttttgat aaataaggcc gtagataatc
    22141 atattagtcc tcacatttat cttcagatca gccaaatgta ttaatgattc cttgactttt
    22201 accatgaatt cggatataac aaaatgatga catctaaaat taccattaaa gatattgcac
    22261 gagaagccgg ggtttctgtg gcgaccgtat cttacgtgtt aaaccagcgc aatgatcaaa
    22321 aaatcagcga agaaacccgc aataaagtgc tacatattag taaccttctt aactatacac
    22381 ctaatcaggc agccaggtca ttagtcacac aacaatcaaa cagtgttgtc ctgtattaca
    22441 aatatgcaga tagcatttta gctagggctg aacaactgca taccattagc tttctatccc
    22501 gcctattgca tgagcaggac tatcagctgg tttgcctaaa tgaagatagc actgaaaaat
    22561 ttgactgggc agaccttatt ctgaccttgg acgttgataa tgataccttt tacaaaattg
    22621 gaaagcttaa tttcaaaccc ttaattgcca ttgatagctt tgttaatgat cccctcttct
    22681 ttcaaattaa tacagattat gctgctctca aagatcaggc taatcagttt tttaaggatg
    22741 aaccttatac cctgctttcc ttgcctatca ctaatcgtga gcgatatgag catgtttctg
    22801 ccttctttcc aagtttgcac attgtaaacg acctaagaga gctaacctac tttgaaaagg
    22861 aaaatctttt actcattgat gagagtttgg atcaattctt tgtgaactct tcgcaaaaac
    22921 tctgctgccc acgtttttcc cccaaaaaag ggcaagttat cttagagacc atcgaatggg
    22981 ccaaaaaacg ccagcctgat aaaaaacata accttctggt gtaacgcctg agaattaacc
    23041 tatcttgact aattccttgt aactcaaaac cttgcctctt tagataaaga agcaaggttt
    23101 tttgatgtct aatctaataa cagggcctga cttgtctcat caatctctaa actgtgtttt
    23161 gtagaacacc caggtcagca ttaataaggt accaaatact tggcaattca taatcagtac
    23221 tggatcctga ataaagaaac taagagcaat cgccagtaga ctcggccaag ccaaacaatt
    23281 aaccatcaat ccaagtcctt cagagaagtt tcgaatcata aatagtcgtg atcgtttagt
    23341 cagagtcaaa aagaaagcgc ctagaccaat cacaataagg gtacccacac acaccatgag
    23401 aacaaacgtc agcaaaagaa aaccaagtac actggcttta ttactgtcat accattgctg
    23461 attgacaaag tccttcactg ctttaactgt tgtcaggtca gcgagtgact gctgctggcc
    23521 tctaacgtga gcacggagtt ccttgccatc aggggtaaca aaacgccatt ctttttttgt
    23581 cacaataatt tgtctggttg attctgatgc caattgctct aaatcgacct ttgtcggtaa
    23641 aacagccaaa accaattcac catctcgtcg aatcagagat tgaccctgaa acgtatcttt
    23701 ctcaatcttt ccttgggtca atgcttgata ggttttgtct gtgataggcg acaaactctt
    23761 agttacaatc cgttccaagg gatacgttgt catgttagca tagtgtaacg taactggaat
    23821 cattattaag gcgttcaaaa aaacaataat aagaagattt tgccaccaag taaactgagc
    23881 tcggctggca aacattgccc taggagaaag gcaatgtgaa atgtaagaaa taggaaattg
    23941 ttttttatct ggcattaaac attactcctt gtcaggttac cctttggtac caccacttgt
    24001 taaaccggaa acgaaatttt tctgtaggaa gaaaaagaga actgaaatag gcactgcaat
    24061 cagaatagct cccgcagcaa ataaggttac cttgggattt ctagcatcat tcgtaataaa
    24121 cgattgaaga ccaactgcta ccgtataatt ttcttgcgcc cttaaaagga atttagccaa
    24181 catgaagtct ccgaaaggac ccataaaagc ccataaggat tgtactgcaa tcattggtcg
    24241 cacaagagga aggacaattt ggtagaaggt cctaaagtgt ccagaaccat ctaacttagc
    24301 agattcgtcc aagtcataag gtaccgtgtc aaaataaccc ttcatcaacc aggcattcat
    24361 aggaatacca ccaccgacgt aaatcaaaat caagaaccag tattggttta aggcattaaa
    24421 gagccacgcc ataacaaagt aagccgttaa agccgccatg gtaggaacca tctgtacgac
    24481 taggaaaaag attaaacttt ttttgcgtcc aaagaaattg taacggctat acgcataacc
    24541 tgtcaaagtg atgactgtta cttgtatgag catggtgaag aatgccacga tcaaggtatt
    24601 ccaataccat cttaagtata aggtatcttg aaagagtgtt ttaaagttag acaaggtcca
    24661 tggcccatca aaatgaaaac taaaggctgt ggtatttcct ggtctaaaag ctgaactgac
    24721 cgtcactagt attgggaata aaatcacgat cactaaggag attagataga gataagtcaa
    24781 taattgggtg aagaaacgtt tgcgtttcat ggatattgaa acataggtct ttctcatgat
    24841 ctctcctcca tatcaaaagc tttaaatttc ttaaaggtaa tcaacgatac cgaaatcact
    24901 attacagaga tgattaaggt cactgccgac gccatcgaaa actgaggcga ggtttgtgtg
    24961 gtcaacttgt aaatccaaga aatcagaata tcagttgtcc cagctccgcc ccccacagta
    25021 ccagggcccc cattattaaa cagataaata atagagaaat tattgaagtt aaaggtgtac
    25081 tgagagataa aggttggtgc tgcaaccgca aaaatcattg gcatggtgat atggcggaat
    25141 ttctgtaaga ctgtcgcacc atcaacggtt gctgcttcgt ataaatcagc tggaattgcc
    25201 tgtaaaatac ctgataccaa aatatagata tagggaaatc ctagccaacc ttgcaccata
    25261 ataacagcca cttttgtcca gaaggggtct gtcttccagg acacaattcc gaagtcaacg
    25321 aaaggaagga atttctcgat gaaaggaaga acctgaacat tcatggcccc aatggaatca
    25381 ttaaagaaat taccaaaact cataatagag ataaatgctg gaacagccca tggtaacaag
    25441 aatatcacac caaagagacg ttttcctctg ataaaggatt gattagcaat aacagccgtt
    25501 gcaattccaa taacaatttg aagacttgtc gctgctaatg tccagatcag cgtccatgac
    25561 aaaacagatg taaatgctgt tttgaaggtg cttaattcta agatattaag aaaattcttc
    25621 aaccctaccc aatccaataa acgatacgga ggaatatgcc taaaatcgta attggtaaaa
    25681 gcaatcagca aggtcactaa aactggaaaa ataatagcga aagccattgc taaataagcc
    25741 ggaatgatga gcaagtaagg aaatcctttt tcataaatcg cttcaagggt ctctttagcc
    25801 gtcaccggaa ccttcttgcc ttcattcatt tgatgtgcaa ctaatttagc atctctcata
    25861 gcaaccaaat gaaaaatacc aaataagact agagtaatta attgcatggc ccccttaatt
    25921 aacataaata aggagtgatc ttgcattgga acacttccaa gactgtaaag acctgttaaa
    25981 gcaggaattc ctagaactac aatttctagt agctctagga agaaaacaac taataagact
    26041 ccccctttaa cgatttgttt attgtatagt tgtcccaaac ctgggataac agatagccac
    26101 atggctttat taggcttctg ttgtctttgg ttctctacca ttttttattc ctcttctcat
    26161 aaatgattta aggttatcct ccttatcata ctaacttcct tttaagctga ctaatttatt
    26221 tttttatagt aatggtttgt gcttcatgac ctgtctttat actataagtc tcaggacttg
    26281 tccataaaac attcccaata ctatcttttt taacaagttt gactgctatt tctttattga
    26341 ttggtagatg agtatcaaag aaccagtttg ggtacttggc aatggtctga gtgttattaa
    26401 atagaggacc aacagcattc ttagcgtcat ttgcccccat ctcaaaaaca tcacccatga
    26461 gatatagttg ttcccctggt actgtcttaa aatcattgat gagtaaacga acaggaattt
    26521 gtttatcagt caatacttca aaggcttggt aactattgct ggtttgctta tcggcagttg
    26581 tcactgaaat gttataataa tttgctggaa ccgtcggtac ttttaaggtg ataagggtat
    26641 ctgaccaaga aaggatctca gcagagattt ctccaaaagt cacttgacct ttagaattac
    26701 caaaaccttg acctgaaata gtaatcttat ttccagcaat acccactgaa gcatcgacat
    26761 ctccaagttg tggtgtcttg tcctctcctt cataagtcca tacagcgact tgccccgctc
    26821 caagttcaaa gctactaata gtgccatctg ctccaactat taattcttga ccgccaagaa
    26881 gaccttctaa tttgtccttg tagctatttt ggggcaaggc tgttttagca ttagtaattg
    26941 tataaccatt cgtttgatct ctattaatag ccactagtgc gacatgatta ccaaatttac
    27001 gctcaaatac caaaacatga tcactaatcc aacgttgttc agttgttcca taagctaaag
    27061 cttgattttg ttttcttaaa ggagctagct tactaatcac tttataggct tgtgactctt
    27121 tattaaaact tggcatatca ccacgattat taggatcttt atcacctgtt gcatactgct
    27181 ctgtaccata ataaatatta ggcacacctc tagatgttaa aagcaaagca taggcttgat
    27241 taacagcagt ttgattatta gccacttttg ttgcgaagcg ttccatatca tgattatcaa
    27301 taaaggtcac ctggtctgtc acttcattag tcacctgatc tctattttca agaaccttgt
    27361 aaaaatctcg catggtaaac gttgaaaaac ctgtatacaa ctgtctaata gcattggcaa
    27421 atctaaaatc taaaagcccc atcccactat tgttagcaaa tgtcgtcata tcataatcat
    27481 cgtcggtatg tcccgagaac cattccccga aaacaaagac attatgtttt tcatagatat
    27541 gactcaacca atttttttgc caaccttgtg acatatgttt aacagcgtca actcggatac
    27601 catcaacacc caggtctaac catttatcaa tagcttcttt catgtactgg tcaactttcg
    27661 gattaatgtt atttaaatca gctagtccgt acattgaatg ataaatagaa ttttcataag
    27721 tactaaaatc ggtccaagat tcatgattaa aaatcttgtc tttatcatct gaaaatttac
    27781 caactaattt accgttttta tataaagcgc catcttcttt gaaagttgtg ccttcttttt
    27841 cggctgtaga cgtatgatta ggagcaaaat caataactac cttaatatgg tgttgatgag
    27901 ctactttgac tagttgttga aagtctgctt cagtgccaaa atgctggttt gttttaaaga
    27961 agtccttagc ccaataccca tgatatgcag cacttccatt agaaggatca atactgtcga
    28021 tattttcaac aggagaagaa atccaaatgg cagaaatccc catatctgtc aggtaaccat
    28081 ccttaatctt ggcgatgatt ccttgccaat cacctccatg gtatttttta aggtcatttt
    28141 tatcaaaaac atcagtctta ccattattag aggtattacc atcgttaaaa cgatctgtta
    28201 caatctgata aatcgtatct gttgaaaaat ctgctttgtt ggtgacagaa gcattatcgg
    28261 cagcagaaac agttagtgga aatgaaatta agccaagtaa aacagcactt ttcgttaata
    28321 acttataagt tttgatatgt aattctctca tcgctttttc cttttaaaat aaccttttag
    28381 ttactaaaca caatatatcc atcctggagt aattgttttt tgtttttagt taccccattg
    28441 cttgtcaaaa tctgtcctcc ttccttaata gaataagcac tctcaccatt gttaagaaca
    28501 agtgaaatgc tttgctcacc taagctgcgt ttcagaatga ggcagtcttc gtcataatca
    28561 atgctaatag ctccttcttg aagagctggc tgttggcgaa gagcaataat cgcttttact
    28621 ttgctaaaga aatccttgtc ccgctcagca tcatcccaag gaaaaccgcg acgcgaatca
    28681 gggtcgtaac ccccttccat tgccacttct gtcccataat acaagcaagg aatgcccata
    28741 aagataaaga gcaatgctaa agcagctaac aatttatctt tggaaccctt aacttgagtg
    28801 aagaaacgat gcgtatcatg agaatccaaa agattcaagt tcatgcgatt gacttgccaa
    28861 gtgtttcgca tcaaaatgtt gcttaatttc tcagccaatt gttttgatgt catggtttca
    28921 aaagcaaagt aatccaaaca ggctttggtg aaagcataat tcattatccc atcatactga
    28981 tcccctgcca aataaggata ggcatcatgc cagttctccc caattaaaat ggcatctgct
    29041 ttttccgctt taaccgcctg acggaaacgt cgccaaaaat catgagatac ttcatcagaa
    29101 acatctaggc gccaaccatc gatacaaaat tctttaatcc agtatcgccc aatctcaatc
    29161 agatagtctt gcacgtctct atttgaggta ttccatttgg gcatatagtt acatccagca
    29221 aaggtttcat agtttactag gtccatggat gggtgttcat catgagtcat aaaccaatca
    29281 aaaaacttag actctttacc gtatctcaag acatcctgaa attccacggc atcactgctg
    29341 gcatggttaa agacagcgtc tagaataatc ttgattccca ttttgtgagc taaatcaatc
    29401 aattcttgca aatcatattt agttccaaat tgtggatcaa tagcgtagta atcactaata
    29461 tcatatttgt gattactaat ggattgaaaa attggcgtta aatagatgac agtaatccct
    29521 aaatctttga ggtaatctaa tttttctgta attcccttta aatctccacc agcaaaactt
    29581 ttaggagtcg gtttttctaa ccaacccatg ttgacataac tgtcaccttt ttcccaatcc
    29641 ccacggttaa agcgatcaac aaagatttga taaaaaaccg cgtcttttgt ccaaggaatg
    29701 acttgatgaa catcaacagc attgatataa ggcatttgga agaaattata aaacccattt
    29761 gaaaaatcgt aactagtagt taacccatct tcactaaaat aataggtttg accttcttct
    29821 tcaattttaa aaatgtaggc caacctcaca tcgtctaatg ttaaagtagt ttcataataa
    29881 gcatgcgtat ggtctgtata ggcaactgac atttccaatt cttcttggaa ttcatgataa
    29941 ccatatttag gcccgtggac caaattaaca gtaatacctc tatcttcttt ggccacgcgt
    30001 aatcggatga caagttcctt ttgagatatg gcaaagcaat acctcgaatc aggaatatgg
    30061 agcattccgg caacattcat ttctacctcc attaataaag tattgacgat tacttctttt
    30121 tctttaaaac gaaaaaatag cagagcgact catacttcta tatttttagt atctgtttca
    30181 tcttcatcaa actaacagaa atagaagctg ggcgtacttc tttatcccag cctcccttct
    30241 ttgccttatt cagcgtattt ttgttcaata gcttccttaa tagtttttgc tgcttctttt
    30301 gcagctttag atgcttcttc cttaccagaa gccacgttaa agaacatatt tgcacctggt
    30361 tcccaaactt cagccatttc tggaatattt ggcattggtt gtgcgctctc aaactgacta
    30421 atcacagctt tcgttaactc attaccctct ttagaagcat agttacgtgc tgttaagtta
    30481 gctggaattt cttgtgtttt atcatagaaa cgtttttggt tttcagcatt ggtcacataa
    30541 tcaaggaatt tttgagcagt cgtttttcct ttagaatagt ttgaaataac ccaagcttta
    30601 ccacctgcga acggttggta ttttttacca tttgtcaaag taggaatttc cattacccca
    30661 aagttaacac cagcatcttt aaaggagcta gctgcccatg gaccatcaat aatgacacca
    30721 gcttttttag aaataaattg ttcagtgata aaatcaccag cttttttagt gtcttgcatt
    30781 ccttgaggcc aagtgccata ccactgtttc gcgtagttta acccttcaac agttccgtcg
    30841 ttacctaggc ctaaatcact tggtttggtt cctttatcac caaagatata accgccataa
    30901 ccggcaatta aaccataacc ataatagaag tctgtccatt tcgccaagaa acctacagat
    30961 tttcctggtt cagaggcaaa agcaaactta gaatcttttt gtaagacttc taattcagta
    31021 aagcttttag gtgcttgagg cactaaatcc ttattataat aagttaccaa agtttcaatt
    31081 acgtctggtg caccataagt tttaccatca atggttacta atttcttaac cgtatcatca
    31141 aactctttgc tgtttcctaa agtaacctca gcgatttgac cttcagttcc taagccacct
    31201 acacggtcaa aaggtgctaa aaagacatct ggtgaagctc ctgttggacc atccgttgat
    31261 agcttatcaa gagtatccat cataccttct tttttgactt taacggtgac tttatgttct
    31321 ttttcaaact cacccttaat actcttaatg taatcaacat atccctcatc aacagagact
    31381 acaatagtct ttccgtctgt ttccttaacg cctttaccac caccacttac gcaagcagtt
    31441 aggggtagca ctgaagctaa ggataaagtt ccaagcacag atgttttttt ccaattccat
    31501 gacataacat gttcctcccg aaatggtttt ttcttaaaca caaatcaaat catctatcta
    31561 ctctcatcat attagcaaat aaaagataac ataaggcatt taaaattaat aacagtaata
    31621 gtttcgaaac ttaaacgttt aagttaagtt tatcgtaatc gctttcattt gtcaataact
    31681 tttttacttt tcttttcttt taagatcata tcagtagttt tcctgctaat tgaaaacaag
    31741 gcatttactg tcacacaagt ctgtcctttc tttttttcta caactttatt tcgtcagcgt
    31801 aaataaaaca aaagctctat aatctcttga atgggtaaat ccactgtaga gattatagag
    31861 ctttttgaat atcaaaaaag tcccataaga tttataatga aaagcaacca aactctcatt
    31921 agaaagactc ttatggaaca tatcaatcat accttacaac acatcggaat taaagacaaa
    31981 aatatcactc taaacaatgt tttgaaggat gaatctccta ctgagctcgt tactacttat
    32041 cagaaaggta gataggaaat cctgatgaag agtgtgtcca agggattatc aattaggtct
    32101 tagattacaa aatagtaatt caggtatgct ctactgtttt caacactagt tctgcaattt
    32161 gttttcgagc ttgcttagct tctcttattg gaaaaataac atacgcatga atcatttttt
    32221 ctgcaataat cagctgatta gcaattcgtt gtcttgttaa ttgatcatgt aaagacataa
    32281 tgtctgggta aaaaatctct tttgtcccaa caaaggtcgt tatttcaggc aaatcctcat
    32341 aatcaccata caaaggactg acataaggaa gttgcatatt accttgacca cctgcccata
    32401 gttcacctat atcacgaaga cgacgagcat ctaggtaagc ttcttctgct tcaaaatcct
    32461 tgtaggcttg atttttaaaa ctaacatcta accaaggaga tataagaatt aattgctttg
    32521 gctggggtgc tgttttagta tctcgtatat acttagcaaa cgccaaagcc atacccccac
    32581 cagaagaatc accaatgaca ctaacttgac tcggtccatt agacaagcaa aattgctggt
    32641 aagcttcaac taatttagga tagacatctt gataagtagc atacggtact ttaggaaagt
    32701 taggaaaaac aaccttggca ttagtcagct gtataagatg cttaaccgtc ttaaaatgaa
    32761 gtttttcggg tcgtcgtaaa tagacactgc cataaagata ataaataaca ggctgatgac
    32821 tttgcttttg atcattaatg ataaaaactt gcatcccgtt cacatcgtat tcttgagttg
    32881 aaaaacctac tatctcttca ggattatcta gatgataagg gatattacga ttacgctgcg
    32941 tctcaacccc cttataatta tcaacttttt tagataactt atactttcta taagcaaaca
    33001 ttttctcaac caaccaactt gaaaaggagc gcttttgacc atattcaact atcaaaatac
    33061 ctagtatcac tccaaaaaaa atcaccacag caataatgac cacttattat cctcgttttc
    33121 taatattatt ttactattgc aagtctttcc tatttgccca aattttacta taaaaataag
    33181 ggttcatttt atagttgggc actggctgct tcgtttctag aaatggttgc actttcttat
    33241 caaaagctaa ccagccattc caaccgagat ggatggtatc ttgcataaag taggactcac
    33301 caccatcttt tgagaagtca gcaatgcgat gaaatccttg tgactttaac tggaatttta
    33361 ttttacgaac tgccgcttga tacttatctt gatttaagcc ggtataatcc gcccaagctt
    33421 tattaacagg agttataaca aagagtacat ctgtttttcg tttagcaaat tctgataata
    33481 aaagctgaaa atcattgtat tctggtgacg ccaggtaact ataattaact tggaaattct
    33541 tataaagatt gtatttaggt gctattcgtt tacgataaaa tgtattttta atcccaaaac
    33601 ggttgttggt tgttgctaat tggcctctct tagttgctaa tgcattcaat tgtttatacg
    33661 aaaatacttt aggtaatccc ttaacgcgag gcaaaattct tttttcatag ttagtagatt
    33721 tgcctaaaaa actaaaaagg gactcttctc tcaatgctac ttgatgttga catttcaaaa
    33781 tagctctgtc taaccgacta agagacttac ccttacttac ttttttcaat aagtttgatt
    33841 tagacacacc agggttaagc tcaagcaaac gctttgctgc aaactgtgat tctttatcag
    33901 ttctagcttt tagtaaaaat tcaatcactt gagtgttaga caagtacatc tgaaccgcac
    33961 taggattaat cccttgagca gtaaaccatt gaggagatac tacaaagatg gcttttttct
    34021 tttgcatttc attggtaatt tgttgcatac cataataatg cgacaaagat gctgatcctc
    34081 tcttaccaat taaaaatggt ctatagctcc gcttgtagcg ctctgcaagc accgaagggt
    34141 gcatactatc cattcgactc cattcgctag aaccaaaaaa aggcacaaaa cgacaagtct
    34201 catctgataa agcttgtctt ttaatcaaac catttttaaa agaactatct gtgatcgcaa
    34261 cggcatttgc tttttcctga gctatggaat gatcaagttg tgtaggaaaa ctaaaaatag
    34321 taatcactac taaaacaaag gcaataagaa gaggacctag aattaaccag agtctcttaa
    34381 gcatgttgca attcctctac accttgaaca atcttagtta ctgtgttcca atcatcacga
    34441 ccaaattctg aaataggtac tttaatattg aacgttgact ctaactcaac aatcaattcg
    34501 actgtcccaa gactatccaa cacacctgca tcaaacaagt cttcgtccat catctctgaa
    34561 acatcttcca taaacaaacg gtcaaacaat tcaattacag tttcttcaat agacattttt
    34621 atacttcctt ttattaatgt agtggtctgt taaaccaaag gtcatttaaa aaaccagaga
    34681 ataacagaag tgaaaacatg acaacgtgga aagttaccac gatacataag acatggaatg
    34741 ccctgctttg aaagaggggt gataagcctt ttttcttacg gtgacggttg atttcttttt
    34801 tcttacgaat ccaagcatca ttaataataa gtcctatacc atggaaaagc ccataagcga
    34861 tataatacca ggttaagcca tgccaaaatc ccatgactag catattaacc agataggcaa
    34921 cacctgaagt gacatttcgg tttttaaagg ttttatgctt aatcaataga tgaaccaatc
    34981 gcataaacac ataatctcta aaccagaagg acaaactcat gtgccatcta ttccaaaaat
    35041 ctttcaaact tgcagataag aaaggcatgt taaagttttc tggtgttcga atacccaata
    35101 ggtaggaaat accaatcgca aacatcgaat aaccagcaaa gtcaaaaaag agattcaagc
    35161 catatacgta cataaccaga atagtttcct tattaaagta gccaccaacc atcaaagcct
    35221 tattttcaag gagaggaagt aagatgccac ccaaacaata ggaaatgata tgcttgtata
    35281 gaaaacctaa catgagatac atgactgcct tattgagcat tgcaaaataa tcatcacgtt
    35341 caggaagttt atgataatct tcctgaaaat gtctgaagcg atcaatgggg ccacttgaga
    35401 aggtggggaa gaaaatcatg aagcgaataa aatccggtaa acgaacctct tggagagtcc
    35461 cgtcacgcat ctcaataatc attccaatac ttttaaaggt caaatatgaa atccctagaa
    35521 aactaaagag tgtttgagaa gaaggacctg ttaggggagc aactttgacc cagataaggg
    35581 ggaataaggc catcgcaata gctaagtaaa acactcctgc actattagca ttctcacggt
    35641 atttctggta agcaaaaaca ctgatgattt gccacaaaag ataaaagaga aaagcaacta
    35701 attgttgata atgatctcct ccaaacataa agagaataaa taccaaactc accaaggttt
    35761 cataagtgct taagcgcttt tgtttaaaaa tcccaatgat gactggtaag aaagccaaaa
    35821 taagatagac aaagtaaatg gggttaccgt aaggttccat gtagggaatg tggctaaaaa
    35881 acatcatcat cggttattga cctcattaat caaagtttta atatctatct taccatttgg
    35941 agttaatggt agactatctc gataaagaaa cttagaaggc atcatataac tcatcatatg
    36001 atccttaaca gaggctttga tagctttggt taactccaat tccctatcaa aacgctcttt
    36061 aaccccatct ttgacaacga tataggccaa gagattttga accttatgtt ctttattgta
    36121 ccttggaaca gccacagccg atgctaccat tggtgattga ttcaactgtt gggaaacatc
    36181 ttctagttca atacgataac cagcatattt aatctgaaaa tccaaacgcc caccatacaa
    36241 caaaatatta tcttctgtca gtgagccaat gtcccctgta tgataagcag gctgtccttt
    36301 aaaagtaaag aaagcttctg cggttttctc aggattgttg aggtaacctt ttgacacagc
    36361 aggccctgta acaataattt caccctgctc ccctgaagat aactccttac catcttcatc
    36421 aataatatag gtcggagaat ctggtttggg gtagccaatc ggcaagcggg tataattatc
    36481 caccatttct ctggtaattt caatagcgga taaggctaca gtcgcttctg ttggtccata
    36541 ggcattgata atcttggcac tcgggaaacg ttcaaagagt tttcgagccg tagaaacggt
    36601 taattcttcg ccatcaaaat aaaaatgcgt taaagctggc atcttagcct ggcaaaaatc
    36661 atcgctaagc atggccatat cagcaaatga aggagtcgat gtccaaatgc caactggaag
    36721 ttgcgcaatc gttgtaaata actgtttaaa gtctgccacc aattcttttg gaagtgcaaa
    36781 taaggttcca cctaaagcca aggtaggtgc ccagtacatg acagaaaggt caaaggaata
    36841 gggtggctgc gccagcattt gtggctgttt aggtacatca aatgctgcat cttcgatcat
    36901 ccagttggta aagctcaaaa gattgtcatg tgaaatttgc accccttttg gttggcccgt
    36961 tgttccagag gtgaaaataa tgtaataatt atcatctcct ttaacagaat gtgttcgctc
    37021 atagggcatt tctgctaatt ttgctgactc aatctctgat agtgagacaa gggaaatccc
    37081 ttcaatagta agagggaatt cctcaatagc aatgattaaa ctgggctttg caatctcaat
    37141 aatcgctaaa atacgttctg gtgctgaatg cacatctact gggatatagg catgaccaga
    37201 tttggttaaa gctacaaaag tagctaacat atcataagtt tgcgccccaa aaaccaaaac
    37261 tggagatttt gccagtaaag ctaagctatc tataaatgca gcaatgctat cagaatctct
    37321 tttgagttgt ccgtaagtgc ggcgttcccc taaacaatca taaactggaa aatcagcctg
    37381 tgtctgagca aactgctcaa tactgtcaat catatcctta atcatcagtc aatctcctaa
    37441 aattcattat aaataaagtt actttgacca tgtcctagat aaccaaagaa atagaccagc
    37501 aacattaaaa tcagataaaa taaaattgtc ttgccaataa aaacagcaat tcctctcatt
    37561 cttgatttgt tttttatcat actttacctt cttgtattag tgaa
//
LOCUS       DAUGJR010000016        34868 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUGJR010000016 DAUGJR010000000
VERSION     DAUGJR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34868
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.016"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            71..949
                     /gene="mvk"
                     /locus_tag="VH800_000804"
     CDS             71..949
                     /gene="mvk"
                     /locus_tag="VH800_000804"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEQ8361883.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYASLDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            931..1875
                     /gene="mvaD"
                     /locus_tag="VH800_000805"
     CDS             931..1875
                     /gene="mvaD"
                     /locus_tag="VH800_000805"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEQ8361884.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGILQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDQWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            1868..2875
                     /locus_tag="VH800_000806"
     CDS             1868..2875
                     /locus_tag="VH800_000806"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEQ8361885.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKEIHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEN
                     D"
     gene            2868..3857
                     /locus_tag="VH800_000807"
     CDS             2868..3857
                     /locus_tag="VH800_000807"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEQ8361886.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(4087..5364)
                     /locus_tag="VH800_000808"
     CDS             complement(4087..5364)
                     /locus_tag="VH800_000808"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEQ8361887.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(5351..6526)
                     /locus_tag="VH800_000809"
     CDS             complement(5351..6526)
                     /locus_tag="VH800_000809"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEQ8361888.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDLAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASISYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            6735..7574
                     /locus_tag="VH800_000810"
     CDS             6735..7574
                     /locus_tag="VH800_000810"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEQ8361889.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDRTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            7654..8151
                     /locus_tag="VH800_000811"
     CDS             7654..8151
                     /locus_tag="VH800_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEQ8361890.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRVIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            8171..8341
                     /locus_tag="VH800_000812"
     CDS             8171..8341
                     /locus_tag="VH800_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361891.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            8471..9700
                     /gene="clpX"
                     /locus_tag="VH800_000813"
     CDS             8471..9700
                     /gene="clpX"
                     /locus_tag="VH800_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEQ8361892.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            9710..10309
                     /locus_tag="VH800_000814"
     CDS             9710..10309
                     /locus_tag="VH800_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEQ8361893.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            10457..11200
                     /locus_tag="VH800_000815"
     CDS             10457..11200
                     /locus_tag="VH800_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361894.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(11258..13357)
                     /locus_tag="VH800_000816"
     CDS             complement(11258..13357)
                     /locus_tag="VH800_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8361895.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVN
                     QTTAKKGISLTITDDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQNDQ"
     gene            13736..14419
                     /gene="rpiA"
                     /locus_tag="VH800_000817"
     CDS             13736..14419
                     /gene="rpiA"
                     /locus_tag="VH800_000817"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEQ8361896.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKNFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPTAG"
     gene            14496..15707
                     /locus_tag="VH800_000818"
     CDS             14496..15707
                     /locus_tag="VH800_000818"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEQ8361897.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     AAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGDPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSVSFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLSHLK"
     gene            15726..16166
                     /gene="arsC"
                     /locus_tag="VH800_000819"
     CDS             15726..16166
                     /gene="arsC"
                     /locus_tag="VH800_000819"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEQ8361898.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAYGLANQAVAEKDIINAMLADPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYIKEDGESVNPIEVKGEKDVIDD"
     gene            16150..16959
                     /locus_tag="VH800_000820"
     CDS             16150..16959
                     /locus_tag="VH800_000820"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8361899.1"
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            17622..18335
                     /gene="deoD"
                     /locus_tag="VH800_000821"
     CDS             17622..18335
                     /gene="deoD"
                     /locus_tag="VH800_000821"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8361900.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYACELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            18328..19116
                     /locus_tag="VH800_000822"
     CDS             18328..19116
                     /locus_tag="VH800_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEQ8361901.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(19195..20100)
                     /locus_tag="VH800_000823"
     CDS             complement(19195..20100)
                     /locus_tag="VH800_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8361902.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            20322..20858
                     /locus_tag="VH800_000824"
     CDS             20322..20858
                     /locus_tag="VH800_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361903.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKVPTGEFE"
     gene            21135..21827
                     /gene="pyrF"
                     /locus_tag="VH800_000825"
     CDS             21135..21827
                     /gene="pyrF"
                     /locus_tag="VH800_000825"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEQ8361904.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYVQG
                     PDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGAVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            21885..22514
                     /locus_tag="VH800_000826"
     CDS             21885..22514
                     /locus_tag="VH800_000826"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEQ8361905.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIKAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            22711..24165
                     /locus_tag="VH800_000827"
     CDS             22711..24165
                     /locus_tag="VH800_000827"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEQ8361906.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPRDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LSMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            24283..25146
                     /locus_tag="VH800_000828"
     CDS             24283..25146
                     /locus_tag="VH800_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8361907.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHQSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYHAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            25175..25825
                     /locus_tag="VH800_000829"
     CDS             25175..25825
                     /locus_tag="VH800_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8361908.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            25958..26611
                     /locus_tag="VH800_000830"
     CDS             25958..26611
                     /locus_tag="VH800_000830"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEQ8361909.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            26743..28011
                     /locus_tag="VH800_000831"
     CDS             26743..28011
                     /locus_tag="VH800_000831"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEQ8361910.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(28069..28710)
                     /gene="plsY"
                     /locus_tag="VH800_000832"
     CDS             complement(28069..28710)
                     /gene="plsY"
                     /locus_tag="VH800_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEQ8361911.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            28845..30794
                     /gene="parE"
                     /locus_tag="VH800_000833"
     CDS             28845..30794
                     /gene="parE"
                     /locus_tag="VH800_000833"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEQ8361912.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKIAYAWTDGEL
                     EDLRREFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            30885..33344
                     /gene="parC"
                     /locus_tag="VH800_000834"
     CDS             30885..33344
                     /gene="parC"
                     /locus_tag="VH800_000834"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEQ8361913.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            33422..34489
                     /locus_tag="VH800_000835"
     CDS             33422..34489
                     /locus_tag="VH800_000835"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEQ8361914.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            34553..34783
                     /locus_tag="VH800_000836"
     CDS             34553..34783
                     /locus_tag="VH800_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEQ8361915.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
BASE COUNT        10895 a         6314 c         7226 g        10433 t
ORIGIN      
        1 cattttctaa tcatttagtg taaaatagta aggtaaaagt ttagaagaat tagtaatgaa
       61 aagacaaaaa atgaacgaaa acattggata tggtaaggca cacagtaaga tcattttgat
      121 aggtgagcat gctgttgtgt atggctaccc agctattgct ttgcctttaa cagatattga
      181 ggtggtttgt catatttttc cagctgataa gccattggtc tttgattttt atgatactct
      241 atcaacagcc atttatgctt ccttggatta tttgcagcga ctacaagaac caattgctta
      301 tgagattgtt tcacaagtgc cacaaaagcg tggtatgggg tcttcggcag ccgtttctat
      361 tgcagctatt agagccgttt tttcttattg tcaagaaccc ctctcggatg atttgttgga
      421 aattttagtc aacaaggcag aaattattgc ccacaccaat cctagtggtt tagatgccaa
      481 gacatgcctt agtgaccatg ccattaagtt tatccgaaac attggctttg aaactatcga
      541 aatcgcctta aatggttatc ttatcattgc agatacaggg attcacggtc atacacgtga
      601 ggccgtcaat aaggtagcac agtttgagga aacgaatttg ccctatctgg ctaaactagg
      661 agctttgaca caagcccttg aaagagcgat taaccaaaaa aataaggtgg ctatcggtca
      721 gctcatgaca caagcgcact ctgctttaaa ggccattggc gttagcatca gtaaagctga
      781 ccaacttgtg gaggctgccc taagagcagg tgctttaggc gctaagatga caggcggtgg
      841 cttgggtggc tgtatgattg ccctagcaga taccaaagac atggccgaaa aaatcagtca
      901 cagattaaaa gaagaaggag ccgtaaacac gtggatccaa atgttataac cgtaacatcc
      961 tatgctaaca ttgctattat caaatattgg ggaaaagaga atcaagctaa gatgattcct
     1021 tcgacctcta gcatttcttt gactttggaa aacatgttca ccacaaccag cgtttccttc
     1081 ttaccagata ctgcaaccag tgatcagttt tacattaacg gtatcttgca aaatgacgaa
     1141 gaacatacca aaatttctgc tatcattgac caatttcgcc aacctggtca ggcttttgta
     1201 aagatggaaa ctcaaaataa tatgccaaca gctgcaggtt tatcatcaag ttccagtggc
     1261 ttatcagcct tggttaaagc ctgtgaccaa ttatttgaca cccagctaga tcagaaagct
     1321 ttagctcaaa aggctaagtt cgcctcagga tcatcttctc gttctttttt tggcccagtc
     1381 gctgcttggg acaaagatag tggtgctatt tacaaggttg agactgactt gaaaatggcc
     1441 atgattatgc tggtcttaaa tgctgcgaaa aagccaattt ctagccgaga gggcatgaag
     1501 ttatgccgcg atacctcaac tacatttgat caatgggtag aacaatcggc aatcgattac
     1561 caacatatgc ttacctatct caaaactaat aattttgaga aagttggtca gttaacagaa
     1621 gctaatgcct tggccatgca tgccacgaca aagacagcca atcctccttt ttcttaccta
     1681 acaaaagagt cttaccaggc tatggaggct gtgaaagaac tgcgtcaaga aggttttgct
     1741 tgttatttta ccatggacgc aggtccaaat gtgaaggtcc tatgtttaga aaaagacttg
     1801 gctcaactag cagaacgact tggcaagaac taccgtatta tcgtttcaaa aacaaaggat
     1861 ttaccagatg tctaattatt gtgtgcaaac aggtgggaaa ctatacctca caggcgaata
     1921 tgctatctta acaccaggac aaaaagcctt aattcacttt attccattga tgatgacagc
     1981 agaaattagc ccagcagccc atattcaatt agcttcagat atgttttccc ataaagcggg
     2041 catgacaccc gatgcctctt atgcactgat tcaagcaacg gttaaaacct ttgctgatta
     2101 tctaggacag tcaattgacc aactggagcc attttcccta attataacgg gaaaaatgga
     2161 gcgcgatggc aaaaaatttg gcattggttc aagtggtagc gtcaccctct taaccttaaa
     2221 ggccttatcg gcctattatc agattacttt aaccccagag ttactcttta aactagcggc
     2281 ttataccttg cttaagcaag gagataatgg gtctatgggg gatattgcct gtatcgctta
     2341 tcagacttta gtcgcctata cctcctttga ccgagaacag gtcagtaatt ggctgcagac
     2401 catgccctta aaaaaacttc tcgtcaaaga ttggggttac catatccaag tcattcaacc
     2461 agccctgcct tgtgactttt tggttggctg gactaaaata cctgctattt caaggcagat
     2521 gattcaacaa gtgacagcga gcattacccc agctttctta agaacaagtt accagctaac
     2581 gcaatcagct atggtagctt tgcaagaagg tcataaggaa gaactcaaga aaagtttagc
     2641 aggagcaagt catctcctaa aagagattca tccagctatc taccatccta agctagtaac
     2701 cttggtagct gcttgtcaga agcaagatgc tgttgctaaa tcttcaggtt ctggtggtgg
     2761 agattgtggc atcgcgcttg cctttaatca ggatgctaga gataccctta tttccaaatg
     2821 gcaagaagct gatatcgcat tactttatca agaaaggtgg ggagagaatg actaaccgta
     2881 aagatgatca catcaaatat gctctcaagt accaatcgcc ttataatgct tttgatgaca
     2941 tagaactcat acaccattcc ttacctagct atgatttgtc tgatattgat ctcagtactc
     3001 attttgctgg gcaagacttc gactttccct tttacatcaa tgccatgaca ggaggaagtc
     3061 aaaaaggcaa agctgtcaat gaaaaattgg ccaaagtagc agcagcaaca gggattgtca
     3121 tggtgacagg gtcttatagc gctgctttaa aaaatcctaa cgacgattcc tatcgtttac
     3181 atgaggtggc agataacttg aaactagcca cgaatattgg tctagataaa cctgtggcgc
     3241 taggacaaca aacggttcaa gaaatgcagc ccctcttttt acaggttcat gtgaatgtga
     3301 tgcaagagtt gctgatgcca gagggtgagc gcgtctttca tacctggaaa aaacacctcg
     3361 ctgaatacgc tagtcaaata ccagttcctg tcattctcaa agaagttggt tttggcatgg
     3421 atgtcaatag tatcaagcta gcacatgacc taggcattca aacctttgat atttcaggta
     3481 gaggaggaac ttcatttgct tacattgaaa atcaaagagg gggagaccgc tcttacttaa
     3541 acgattgggg acaaaccact gttcagtgct tactgaatgc acaaggactg atggaccaag
     3601 tggaaatctt agcttcgggt ggtgtcagac accccttgga catgattaag tgttttgtct
     3661 taggagcacg tgcagtggga ctctcacgca ccgttttaga attggtcgaa aaatacccaa
     3721 ccgagcgtgt gattgctatc gttaatggct ggaaagaaga attaaaaatc attatgtgtg
     3781 ctcttgactg taaaactatt aaagaattaa agggagtcga ctacttacta tatggacgct
     3841 tgcagcaggt caattaggct tcatcacctc tacaatagtg tcacctacta caaagatgat
     3901 agagcttttt tagaacataa tataaaatat ttataaatac ctcatcaaac tcagaataga
     3961 gtagatgagt aaatagagta tgttatggag actatttcta agacttgtat gtatagaaat
     4021 aaagattaaa cacccatgta aaccaattgt ttacatgggt gtttgcctta tattagttgt
     4081 ttaaatctaa gactgtctta gctgggataa gtaaaaatgt gctttttcta gatttattgg
     4141 tttatcagct agtaaagcat taactaaagg agcaatttcg tcttgggttg cccccgccaa
     4201 aagagctaat gatttcgcat gtagtttcat gtgaccagct tggatgccag atgaggtcag
     4261 agcttttagt gcagcaaagt tttgagctaa ccccacagat gcaatcaatt gggctaatgt
     4321 tttggcatca ggttgattaa gaagatcatg tgcgatagaa acagtagggt taagcccgat
     4381 agatcccccc ttactagcaa taggcatagg gagggtcatt tggccaagca gaacttgttt
     4441 atcttggtca aaatgccact gactaagtcc ttgatagcta ccatttcttg aggcataagc
     4501 atgggcccct gcttcaatag cacgccagtc atttcctgtg gctattacca ctgcatcaat
     4561 gccattaaaa atacctttat tatgagtagt agcccggtaa ggatctactt gagctagtcg
     4621 gctggctagc tctatttttt gagctaactg tagggatttt gttttatcgt gatctaaaag
     4681 gcgcacggga atctcacaac tagtagtaac aagcgactct gttgcgtaat tagataaaat
     4741 cgccattaga caatgcccct tagacagtct tgttaaatca ggaacaagag cttccatcat
     4801 agtattgacc atatttgctc ccatagcttc ttgggtatca acagtcagat agaaaatcaa
     4861 aaattctcct ttttcttcca aatgaatggt tctagcgcct ccacctcttt taacaatgga
     4921 aggataagct ttatttgcca atgcaattag cttttttgtt ttatgaagga tggcggcttt
     4981 agcgttatct atttggtcga tatcgtaaag aacaatttga ccaatcattt gtcggtttag
     5041 ggtttgagct ttaaaaccac ctgagcgttt gattagtttt gctgcgaaag atgctgcagc
     5101 aacaacagaa ggttcttccg tgacaaaagg catctgataa gttgaaccgt tgacaagaaa
     5161 atcaggagct atgctaaagg gcaaagccaa tcgtcctaag acattttcag tcatttgatt
     5221 agctgtttgg ataggcaaaa gaacgtctgt tttgagttga tttaagtttt cagcattaag
     5281 tagtttaaat ttttcgataa gttggaggcg ttcttcgaat gttttctttg aaaaaccgct
     5341 ccagttaaga ttagtttttg tcattggtat gatagatcct tcgatgctcc ttgatggctg
     5401 ttagagcaaa ttttccagtt aagtaaatgt caaaattggc attaccatta tcatctaatt
     5461 ggacttgttc gtagaaaagg tcttcgtatt tagaaacaga aagacgtgtt cgttgatcca
     5521 gtaaagcttg tcgattagtc attaacattt tatcgtaccc agcaactaac tgaccggaat
     5581 aaaattcact tacggcaccg gaaccatagc taaaaaaacc aattttatct ccagattgta
     5641 atactttact attttcaagt aaagataaca atcctagata aagtgagcca gtataaatat
     5701 ttccaatttg tttgctataa ctaatagaag cttgaaaggc ttctattagt ttttccctgt
     5761 gttcaggagg tactgtgtta tccataatgt tatttagacc ttttagggct aacttgggaa
     5821 atggaatatg gaaacaaact gcagcaagat cagataactg aaggttttct cttttctgat
     5881 aagcttgcca cgtggtttct aagcaattga gatattgctt ggtagagtaa ataccatcaa
     5941 cataaggtgt gaaactatag ttaggcctcc aaaagtccat aatatcccta gtttgagcca
     6001 cattatcttc atttagagca agaatacgag ggttagcagt taccaaaaga gcaatactac
     6061 cagagccttg agtcgattcc ccaggagatc ctacaccgta tctagcaata tcactagcaa
     6121 taacaaggac acgagaatct ggcttagaag ccacatgcag tttagcatag tctagagcag
     6181 cagttgcgct atagcaggct tgttttactt caaaggaacg tgcaaaaggc tggataccaa
     6241 ctaagtgatg tacatagata gctgatgcct ttgactgatc agtactcgat tcagttgcca
     6301 aaataaccat atcaatctta gctcgatctt cgtcggttaa aatttgatct gctgcagaag
     6361 cagctaaagt aataatgtct tcagtgattg gtgccacact aaaagactca atgagtagcc
     6421 cttgactaaa ttttgctgga tccacttggc gtgcaagcgc taaatcttcc aatttcaaga
     6481 catattgact ggttgcaaaa ccaatcttat caattccaat tgtcatattt gtccttcttt
     6541 tagttatttt tatagtctta cccattctat cacattttac tgcaaaatta gactgataaa
     6601 gttatttgtt ttatccttta atagttaaaa tgttcatgac cacatgaagt ttttcgaatg
     6661 tttatttatt ctggtatttt ttggtaaaat tagttagaat agtatgaagt atgcttacag
     6721 aaaggttatt agagatgaca aaagctgacc agatttttaa agctaatatt caaaaaatta
     6781 taaacgaagg atcattgagt gagcaagcac gtcctaaata taaagatggt cgaacagctc
     6841 attctaagta tattactggg gcgtttgctg aatatgattt agctaaagga gagtttccca
     6901 tcacaacttt acgacccatt ccaattaaat ctgctataaa ggaattattt tggatatatc
     6961 aagatcagtc taacagttta gatgtgctag aagctaaata taatgttcat tattggaatg
     7021 aatgggaagt tgaccagaca cgtactattg ggcaacgtta tggtgctgta gtcaaaaaac
     7081 atgatatcat ctcaaaaata ctaaagcaat tagcagaaaa tccttggaat cgtcgtaatg
     7141 tcatttctct ctgggactat gaagcatttg aggagacaaa agggttgttg ccatgtgcct
     7201 ttcaaatcat gtttgatgtt agacgtgtag gggaagatct ttatttagat gctagtttga
     7261 cgcaacgttc taatgacata ttagttgctc atcacatcaa tgccatgcaa tacgttgcct
     7321 tgcagatgat gattgctaaa cattttggat ggaaaatagg taagttcttt tattttgtta
     7381 acaatttaca tatttatgac aaccaatttg atcaggctca agaattgcta aaacgacagc
     7441 cagttgctag tcagcctaag cttgttttaa atgttccaga taggactaat ttctttgata
     7501 ttaaaccaga tgattttgaa ttacaaaatt atgatccagt gaagcctcag ttgcactttg
     7561 accttgctat ttaaacttta tttagatttt ttgtgagcat tttgttcata aatttggtaa
     7621 aataaataga gtttaaaatg aaggaaataa ttaatgacaa aggaaattat tgctatttgg
     7681 gcagaggatg aagcagggct tattggtgtt gcgggtaagt taccatggta tttaccaaaa
     7741 gagttagaac attttaaaaa gacaacgcta catcaagcaa tcttaatggg ccgtgtgact
     7801 tttgaaggaa tgaattgcaa aagacttcct caacgtcaaa cccttgtcat gacaagaaat
     7861 agagattatc aagtagatga ggtgttgaca atgactagta ttgaaaaagt cttggagtgg
     7921 taccatgcgc aggataaaac actttatatc attggtggga ataaggtttt agaagcgttt
     7981 aatggttatt tcgatcgtgt cataaaaaca gttatccatc atcgttttaa aggagatacc
     8041 taccgaccaa atctagattt tagtcatttc acgcaagaaa gccaaacgtt ctatgctcga
     8101 gacgctaaaa atccttatga ttttaccgtt actgctttaa aacacaaata gtctgaggag
     8161 atgataagcg atgcaacgta gtatttttgg agtatttacg gcttttttgt gcgtgatttg
     8221 tgttctttgt gccattccag cttttaaaaa gaatcgttat ggcttagcaa gtctgttctt
     8281 attaaatgcg tttactaatc tggttaatag tattcacgcc ttctatggta cattgttttg
     8341 agatgcgact tgcaaagaca gcactggtga agatttagct atcaagcaag aatcaccaaa
     8401 aaccaataca acacattgac taatattaaa attcagtaaa agataagaga aagtaagaga
     8461 attataagaa atggcaggaa gtagaactaa cgatattaaa gtatactgtt cattttgtgg
     8521 taaaagccag gatgacgtta aaaaaattat cgcaggaaat aatgttttca tctgcaatga
     8581 atgcgtagct ttatcacaag aaattataaa agaagaattg gctgaagaag tccttgccga
     8641 tttgacagaa gttccaaaac caaaagagct ccttgatgtt ttaaatcaat atgtggttgg
     8701 tcaagatcgt gctaaacgtg ctttatcagt tgctgtgtac aatcattata agcgtgtctc
     8761 gtttacagaa agtcgtgatg acgatgatgt ggatttacaa aagtccaaca ttttgatgat
     8821 tggaccaaca ggttcaggaa aaaccttctt agcacaaact ctggctaaaa gcctcaatgt
     8881 accatttgct attgcagatg caacttcttt gactgaagca gggtatgttg gagaagatgt
     8941 ggaaaatatt ttactcaaac tgattcaggc tgctgactat aatgtcgaac gagcagagcg
     9001 tggtattatt tatgttgatg aaatagataa gattgctaaa aaaggtgaga acgtatctat
     9061 cacacgtgat gtatctggtg aaggtgtaca gcaagccctt cttaaaatta ttgaaggtac
     9121 ggtagcaagt gttcccccac aaggtgggcg gaagcaccct aatcaagaaa tgatccaaat
     9181 tgatacaaaa aatatcttgt ttattgttgg cggggctttt gatggcatcg aggagatcgt
     9241 taaacaacgt ttaggtgaaa aagttattgg ttttggtcaa aacagccgta aaattgatga
     9301 caatgcttct tatatgcaag aaattatttc agaagatatt caaaagtttg ggcttattcc
     9361 agaatttatt ggccgcttac cagttgtggc agcccttgaa caactaaaca catcagattt
     9421 gattcaaatt ttgacagaac caagaaatgc cctggtcaag caatatcagg ctcttctttc
     9481 ttacgatggc gtcgaattgg catttgataa ggaagcctta gaagccattg ccaataaagc
     9541 cattgaacgt aagacaggag cacgtggtct tcgttctatt atcgaagaaa cgatgcttga
     9601 catcatgttt gaaattccaa gccaagaaga tgtcacaaaa gtgcgtatca ccaaggctgc
     9661 tgtcgaaggc aagtcaaaac ccgttttaga gacagcttaa ggagaaataa tggctgaaga
     9721 acaagtctta aatacccata acgcatcaat tttattgagc gctgccaata aatctcatta
     9781 cccccaagat gatttgccag aaattgccct cgctggacgt tcaaatgttg gtaaatcaag
     9841 ttttattaat accatattgg ggcgcaaaaa tttggcaaga acctcaagca agccaggaaa
     9901 aacccaacta ttaaattttt tcaatattga tgacaagctt agatttgtgg atgtccctgg
     9961 ttatggctat gccaaggttt ctaaaagtga acgggccaaa tggggaaaga tgatcgaaga
    10021 atacttaacc agcagagaca atctgcgtgc agtcgtgagt ttggtggatt tacgtcatgc
    10081 cccttcaaaa gaagatattc agatgtatga ctttttgaag tactatgaca ttcctgttat
    10141 tgttgtggca accaaagcag ataagattcc tcgtggcaaa tggaacaaac atgagtctgt
    10201 ggtcaagaaa gctttgaatt ttgacaaatc tgatactttt atagtatttt cttcggtaga
    10261 acgtattggt atcgatgatt cttgggatgc tattttagag caggtctagc gataggtgtt
    10321 gatttatcta tgctaaaaca ttctcagtag agggtgtttt tcttatcgaa aacataaaaa
    10381 atcatagtta ggtttaccga ttttacttga cgccttaatg atgacatgct agtattttat
    10441 attaaggaga tgagtcatga cacaagtagc ccaagggcgc tctaaaggaa agtcattgtt
    10501 atgccatcaa tgcaatgccc tttttgtatt tattattttt cttatcttgc ttgctgtact
    10561 ttttggtgtt cgatatcgta atagctctat tgaaggtatc tggcgaacaa caagcattga
    10621 tcagaagtta ggcgatgatt ttgctaaacg tcttactggt ttgcatcaga gccctcttat
    10681 tgatgatagt ttattaacgt catctcagat gatactaaca gttaaaaata acaacgttga
    10741 cttgagtttt agtgttcaag ttgaacgaga catttttgtc aaacgtttag ctgcttatca
    10801 ccaaaatgaa ttattaaaga cattaaagga aaatcattta gttgttggtg acttgagtag
    10861 taaagaacgc caaattattg agaatagtat gccagctagc catgaattag aaatgatttt
    10921 agatcaagct tttgagaaat tagcttctca gatcggaggc aaatataatc aaaaaacagg
    10981 acatttatct gctgttgttc tcaaaggaaa agttaatcgt attttgcaca ccattgatat
    11041 caaagaagaa gtagcagcgg gacatacttc tttttcaaaa ggattactca cacctaatgg
    11101 ttattttgat tacaccagat ttggaaagaa acttgagtta ttaggcgatg aaaaaattat
    11161 ttttaaaaaa gcgctaaaaa aaagtccgtc aagtgtataa cgtagtcaca agacggattt
    11221 tttcatgttt tgaaaattat tcaattgaag aagtttatta ctgatcgttt tgcctaatca
    11281 ctagttgtcc ttcttttagg attgcctgaa gttttttgac ttctggatgg tcaagataat
    11341 aatcagttat acggtcacga atttcctgtt cgataatacg tcgtaatgga cgagctccca
    11401 tagcgtgatt gtaccctaaa tctatcaaat gagctttagc gtcatcagta atcgttaaac
    11461 taataccttt ttttgcggtg gtttgattta cttcagctag cattaaatca acaatttctt
    11521 ctaaactttc tttttgcaga tgattaaatt taatgatact attaaaacgg ttcaaaaact
    11581 ctggtctgaa ataaggtgca atgcgatcca taatgttaga ctcagaagtt tccgtatctt
    11641 gttggccaaa accggcattt gatgtagcaa taataacggt atttttaaag ttaatagtat
    11701 ttccttgtcc atctgtcaat cgtccatcat ctaatacttg tagaagaagt gtaataattt
    11761 gaggatcagc tttttcaatt tcatctagta agacaatagc ataagggtta cgacgaacac
    11821 gctcagttag ggtattatta ttatcatcgt agccaacata accagccgtt gtcccaatca
    11881 attttgacac agcagtgcga tcgttatatt cggacatatc aagtcgaata atagcatctt
    11941 tggaaccaaa taaatcaagt gctaattgtt tagctaactc tgttttacca acaccagttg
    12001 gacccacaaa aaggaaagaa cctattggac gtttaccatc atcaaaacct gcccgatttc
    12061 gtcgaatagc acgtgctact gctgcgacag cctcatcttg tccgatgaca tggcttttta
    12121 agcggctgct aattcctttg agcctttcta aatcattagt ccccatgtta gagacaggaa
    12181 taccagttaa gcgctctaca gactctgcga tatcattgac tgtagcagtg acattttggc
    12241 tttggttatg ttgctcaatt tgcttttgta atgtttcaat ccgtgttttt gctgctaaag
    12301 ctttttcaaa gtcttctttg gcgacagctt tttcttgact ctctttttgt ttagctattt
    12361 cagtttcgag tgtttttaag tcagtgaccg ggtgttgcgc agctaaatga gcagctgtca
    12421 tatccagtaa gtcaattgct ttatctggca ggctacgctg tgggatgtat tgaatagaat
    12481 aatcaacagc agcttttaga acattatcag gaagggtaat atggtggtgt tgttcataaa
    12541 gattacgaat acccattaaa atgtgaaaag tatcttcagc tgatggtgca ttcactttaa
    12601 cttcattaaa gcgacgagca agagcagcat tttttaaaat agtattgcgg tattcgtctt
    12661 gagtagtagc accaatcagt gttaattctc ctcgtgacaa ggctggttta agaatatctg
    12721 caagtccctt tgagcctgaa tcactgcttg tggcaccagc accaactatt tgatgaattt
    12781 catcaaaaaa taagatgata ttcccagctt cttttacttc ttgaatcaag ttttgaatgg
    12841 tctcttcaaa ggaaccacga tactgtgtac cagcttcaag actagaaata tcaattgata
    12901 cgatttcctt gtttttaata gcagctggga catctccatt aacaatggct tgagctaaac
    12961 cttcaatgac tgcagtttta ccgacaccag catctccgac aaggacagga ttatttttag
    13021 ttcgtcgtgc caagatttca gcggtatctt gaatttcttt gttacgacca atgacggggt
    13081 caagatgccc ttgacgagct tcttgtgtta agttagttcc gagttgagtc aatacactat
    13141 cagctttagg tgttaacatt tgagaatttg ttgctttggt tgtcgctaca gggagttgtc
    13201 ctgtttgacg atagtgttgg aattcttcgg gagttatttc gcgaccgtta acgagatagc
    13261 ggggattttc gctacgataa ccacccatgt ttgccattaa ttgattgaaa atatcatcca
    13321 tatttacaaa aggatcttta ccagaaaaat gtgtcatatc agttacctcg caataaaaaa
    13381 tagactataa gatgtttgta agcagtcgca gaatcgttgt taggatttca catgatagga
    13441 aatcctttgc taataaaatg attcagacat tatttttact catcttatag tattattata
    13501 atcaaaaggt cagtaaaggt caaacaaaaa acacttgatt ttcaaaaagc taaataaaca
    13561 cgaaaagtaa gtgcttatat gatgacttta gaataaatca taagttttaa aaagatcatc
    13621 ctattctata gcacttaggc tgtcaatgag agaaaaacaa atgttttcat taacaagttg
    13681 gcgctttcat ggtataataa agtgctaaga cgcaattcta ttataagggg gaatcatgga
    13741 agcactcaaa aaaattgccg gtgttaccgc tgcgcaatat gtgactgatg gcatgaccat
    13801 tgggcttgga actgggtcaa cggcttacta ttttgttgag gaaattggcc gtcgcgtaaa
    13861 gcaagaagga ctgcaagtgg ttggtgtgac tacgtcaagt gtgactagca agcaagcaga
    13921 agtcttgggc attcctttaa aatcgataga tgatattgat agcattgacc tcaccgtaga
    13981 tggtgctgat gaagtggata agaatttcaa tggaatcaag ggtggcggcg cagccttact
    14041 aatggaaaaa attgttgcaa caccaacaaa agaatacatc tgggttgttg atgcttctaa
    14101 aatggtagag catctgggtg cctttaagtt accagtcgaa gtcgttcaat atggtgctga
    14161 tcgtttgttc cgtgtctttg aaaaagctgg ttacaaaccg tcttttcgta tgaaaggtga
    14221 tagtcgtttg gtgacagaca tgcaaaacta tattattgat cttgatttgg gttgtattaa
    14281 agatcctgtt gcttttggtc acctgctaga tggaacagtt ggtgttgtgg aacacggtct
    14341 ctttaatggt atggttgata aggtgattgt tgctagtaaa gacggcgtta ctgttttaga
    14401 agcgcctaca gcaggctagt cttagcatat aacagcgtta atatatttta taggtattgg
    14461 ggagtcaacc gtaacctccc ctagattgga gacttatgtc aaaatttaat cgtattcact
    14521 tggttgtttt agactctgtc ggtattggtg cagcaccaga tgctgacaaa ttctttaatg
    14581 ctggtgtagc tgatacagat tctgacaccc tcggtcatat ttcagaagca gcaggcttat
    14641 cggttccaaa tatggcaaaa attggacttg gaaacatttc tcgtccaata ccactaaaaa
    14701 ctgttccaac agaagacaat cctactggtt acgtgaccaa attggaagaa gtatctcttg
    14761 gaaaagatac catgacaggc cattgggaaa ttatgggctt gaacattacg gaaccttttg
    14821 acactttctg gaatggtttc ccagaagaga ttttaactaa gattgaagaa ttctcaggcc
    14881 gcaaaatcat tcgcgaggcc aacaaacctt attcaggaac tgcggttatt gatgattttg
    14941 gtccgcgtca aatggaaaca ggtgagttga ttgtttacac ctcagcagac ccagtgcttc
    15001 aaattgcagc ccatgaagac attattcctg tggaagagct ttacaagatt tgtgaatatg
    15061 ctcgctccat cacgcttgaa cgccctgccc ttttaggccg tattattgcg cgtccttatg
    15121 taggcgaccc aggaaacttt acacgtacgg ctaaccgtca tgactatgca gtgtctcctt
    15181 tccaagatac cgttttgaac aaactggctg acgcaggtgt cccaacttat gccgttggta
    15241 agattaatga catctttaat ggttcaggta ttacaaacga catgggacat aataagtcga
    15301 acagccatgg tattgacacg cttattaaga ctcttcaatt acctgagttt actaagggat
    15361 tctcctttac taacctcgtt gattttgatg ccaactttgg tcatcgtcgt gacccagagg
    15421 gttatcgcga ctgcttgcat gaatttgaca atcgcctacc tgaaatcatc gcaaatatga
    15481 aagaagacga tttgcttctc atcactgctg accatggtaa tgacccaacc tatgcaggca
    15541 ccgaccacac tcgtgaatac attccattgc ttgcctactc tgtatccttt actggaaatg
    15601 gtcttattcc acaagggcat tttgcggata tttcagcaac tgttgcagaa aattttggag
    15661 ttgatacagc catgattggg gagtcattcc ttagtcactt aaaataagaa agttagtaat
    15721 tgataatgga agaaatcacg atttatcata atccaaactg tggcacttca cgtaatgttc
    15781 ttgccatgat tcgccatgca ggtattgagc ctactattat tgagtatttg cagacgccac
    15841 ctaatcggga gactttaatt gagctcttac aatcgatggg aatctctgca agagaactct
    15901 tgcgaaccaa tgttcctgaa tttgaggctt atggattagc aaatcaagca gtagctgaga
    15961 aagacattat taatgccatg ttggcggatc caattttgat caatcgtcct attgttgtga
    16021 ctcgcaaagg agtaaaactt tgccgtcctt ctgagacctt actggatatt cttcctgttc
    16081 ccctgcctag tccttatatt aaagaggatg gcgagagtgt gaaccctatt gaggtaaaag
    16141 gagaaaaaga tgtcattgat gactaaaatt aacgaaacaa aagacttttt agttactaaa
    16201 ggaattgaaa ctccagaatt tggattaatt ctgggttcag gccttggtga acttgctgaa
    16261 gaagtagaaa atgctattgt tattgattat gcagatattc caaactgggg caagtcaacg
    16321 gttgttggcc atgctggaaa gttagtttac ggagatttag ctggccgtaa agtgctcgcc
    16381 ttacaaggac gtttccattt ttacgaagga aatccgcttg aagtggtgac tttccctgtt
    16441 cgtgtcatga aagctctggg atgtgaaggc gttcttgtca caaatgcagc tggtggtatc
    16501 ggctacggcc caggtacctt gatggcaatc acagaccata tcaatatgac cggaaataac
    16561 ccactaatcg gtgaaaactt ggacgagttt ggtccacgct ttcctgatat gtctgatgcc
    16621 tatactaagg tttatcgcaa taaggcacat gaagtggctg aaaaaatgaa catcaaacta
    16681 gaagatggtg tttatatggg cttgactggt ccaacttatg aaacaccagc agaaatccgt
    16741 gctttcaaag tattaggagc agatgctgtt ggcatgtcaa ctgtaccgga agttattgtg
    16801 gctgctcatt ctggacttaa agtgcttggt atttcagcta ttacaaactt tgcagctggt
    16861 ttccaatcag aattgaacca tgaagaagtt gtggaagtga cccaacatat caaagaagat
    16921 ttcaaaggtc ttgttaaagc tattttagcg gagttgtagg acgaacaaaa tcaactggag
    16981 cattattaca ggaatgttat tttatgtcgt cagtttggca catctgttcg caataaaaaa
    17041 atcaaaaaat aatcacggag tgtgagttcc atgaatgttg aactcagatt ctagcttttc
    17101 taactaacat aaccaacgaa gggaaagaga cgtattcggt ttaaattgag tatggactcg
    17161 aacatttctt cgtattaatt tttaaataat aaaggaaaga gagttagtcc tttcttattt
    17221 gaactcgatt tttagctctc ttctattcaa tatcaattat gaaaggaatg gggttgtatt
    17281 caattgaata cgggcggaaa gctcggaaac tagataaact aacttttgag ctcacacatg
    17341 gcgttagttc cctaaatttc agtcgctttc tgtccgccct ctgaccttct acaaaataaa
    17401 aggaaaggta gggctaactg tattcattga attgaatacg ggcggagaac tgtttttctt
    17461 ccttataaaa aataaaaaaa taagaaaggt gagggctgag ttcattaatt tgaattcggg
    17521 ctaaggactt ggtcaaaaag ataagttgtc tagaaaatca ggattttctg ccaacttcct
    17581 attttgccat cgttctttta acgccctcag tatcataatt tatgtctatc catatttctg
    17641 ccaaaaaagg cgatattgct gataaaattc ttctacctgg agatcctttg cgcgcgaaat
    17701 ttatcgctga aaatttccta gaagatgcag tgtgttttaa cgaagtgcgt aacatgtttg
    17761 gctacacagg aacttacaaa gggcaccgcg tttctgtcat gggaactggt atggggatgc
    17821 cttcgatctc tatctatgct tgtgaattaa tcgttgatta cggtgtcaaa acattgatcc
    17881 gtgttggtac tgcgggtgcg attgacccag aagttcatgt gcgtgaattg gtgcttgccc
    17941 aagcagcagc aaccaactca aatattatcc gtaatgactt cccagaattt gatttcccac
    18001 aaattgctga ttttggttta cttgacaagg cttaccatat cgccagagaa atgggagtaa
    18061 caactcacgt tgggaatgtg ctttcttctg atgtctttta cactaacatg cctgagcgta
    18121 atatggctct tggtaaattg ggtgttaaag ccatcgaaat ggaagcagca gctctttact
    18181 atttagctgc tcagcaccat gtcaaagccc ttggaatcat gacgatctca gataacttga
    18241 atgatccaac cgaagatact acagctgaag agcgccaaac aactttcact gatatgatga
    18301 aggtcggctt ggaaacctta attgccaatg actaataatc aaacactaga catccttttg
    18361 gatgtctatg cttataatca cgcctttaga attgctaaag ccttgccaaa tatccctaaa
    18421 actgccctct atttactaga gatgttaaaa gagcgcagag aattgaacct tgcctttcta
    18481 gcggaacatg cagcagagaa tcggaccatt gaagaccagt atcactgttc attatggctt
    18541 aaccaatcgc ttgaagatga gcagattgcc aattacattt tggatttaga agttaaagta
    18601 aaaaacggtg ctattattga tttcgtcagg tcagtgtcgc ctattcttta ccgacttttt
    18661 ctcagactaa tcacgtcaga aattccaaac ttcaaggctt atatttttga tacaaagaat
    18721 gaccaatatg atacctggca ttttcaggcc atgttggaat ctgatcacga ggttttcaag
    18781 gcttacctgt ctcaaaagca gtctcgcaat gtgacgacca aaagcttagc agacatgttg
    18841 acgttgacct ccttacctca ggaaatcaag gacttggttt ttttgttacg acattttgaa
    18901 aaggctgtcc gtaatcctct ggctcatttg attaagcctt ttgatgaaga ggaactgcat
    18961 cgcaccactc atttttcttc tcaggctttt ttggaaaaca ttatcacctt ggcgactttt
    19021 tctggtgtaa tctaccgacg tgagcctttt tactttgatg acatgaatgc cattattaaa
    19081 aaggagttga gcctttggag acaatctatt gtctgatatt tatcaaaaaa cacgataact
    19141 tgaccgatac aggtcttact accgtgtttt ttagtatgac gattgaaaaa gacattaatc
    19201 aaaggttact tcttcgagaa ggtattcgat aaaacgttcc cccattttgg acaagttggc
    19261 tttttcatgc ttgataaaaa caatgtcaat ttcgtcaggg acatctagcg ggatagccac
    19321 aatctggtca ccatttagat tgctatttag aataccactg gcaacggtgt agccatctaa
    19381 accaatcatt aagttaaaga gggtggcacg gtcactgacc acaattgatt tgttgtgggg
    19441 catctgggac atcatctctt ctgaaaaata aaaggagttg tgaatccctt ggtcatagct
    19501 caggtaagga aaatctctca agtcgtccat gcttaatagg cttttagttg ctagaggatt
    19561 tgatttgctg acaaaaatat gaggctgtgc cttaaataat ggagaggcgg tcaaatgatt
    19621 gtcatcaaat aatttggtca agacatctcg gttatagtcg ttgataaaga gaacaccaat
    19681 ttcagatcga aagtttttga catcatcaat gatttcccaa gttcttgtct cgcgcaaaaa
    19741 gagttcatac cgagtcatgt cggtccgctt gaggagtgag acaaatgcat tgactacgaa
    19801 ggcataatgt tgagatgaaa cgctaaagag ctctcggcca gtattgtggt ttttatagcg
    19861 gtcttctaac agtgatgttt gctctataat ttggcgagca taagataaaa attccacccc
    19921 atcttttgtc aaggtgatcc ctttaggatt tcggttgaaa atggtaatgc ccatctccat
    19981 ttccaaatcc ttgaccgcat tggatagact tggttgtgtg ataaataatt gcttagcagc
    20041 ttcattcata gagccgcact caacaatttt gataatataa tgcagttgtt gaattctcat
    20101 aagtacagtc tagctcaaaa aaaataaaga cgcaagcaca aacgtcatca tgggtttaga
    20161 actttgaaaa agcgctggag tcttttctca atatggccta ggataaatat gattcaattt
    20221 tgagagttga atctatcaat ttcattgccc ttttattttt cttgtgttat attaatagta
    20281 ttaacaaata ggtatttttc taatcaaagg gtggtggtcg tgtgaatgtt actgaacaaa
    20341 atagtcatca aatcttaatc caaaagttat tggtcagtat ccactatttg actctttttc
    20401 gagatgaact gaagcttgta gaacgaactc cttctatact tggaggggaa tttccagctc
    20461 atttagtaca gtctgagttg ggagatattg ttgcggccat tgataccttg gatatgcagc
    20521 aacgcttgat tgagtctacc ttttggtatg aagaatcagc ttttaagttg atgaacaaaa
    20581 ctttggatat tgtcgataat tggattaaag gagtggatca tctgatagat ttatgccagt
    20641 ccaaagaagt ctttcaaatt attattggag ataaacgcat tcgagttttt ggggtcttaa
    20701 gtgatgtttt ttcatcttta aaagtgagtg ctttgtcact taaggaagct cctattccgg
    20761 atgtgctcta tgaacatatc cagagggtta atcttgaaga agaagctttt ataaaatatt
    20821 accaaagccc taaggtaccc acaggtgagt ttgaataaat gattgggtaa aaatgataaa
    20881 atgagttgac gtaagtatac aaaaaaagat atagtaggaa agatgtgttc aaataacaaa
    20941 aagttttgac atcttgtttt aaaaaagcta taatagttta aatttagaca cctttaagtg
    21001 agtccagaga ggcaaacaag gtatacaaga taaaaaaagg gaattccctt ttagtttgct
    21061 gtagcctcgc ttctttggta gcgaggcttt ttggtgctta atgagatatt gacacattat
    21121 agaaaggata agttatgaaa gaagaacgcc caattattgc tttagacttt tcatcatttg
    21181 aggagactaa agcattttta gacttatttc cagcagaaga aaaactatac gtgaaaattg
    21241 gtatggaatt atattatgtg caaggaccag atattgttcg gtatatcaaa tcgttagggc
    21301 ataatgtatt tttggattta aaattacatg atattccaaa tactgttcgt gctgctatgg
    21361 cagttcttaa agaattagat attgatatgg caactgttca tgcagctggt ggtgtagaga
    21421 tgctaaaagc agctcgagaa ggactaggtc aaggccctac cttaattgcg gtaacgcagc
    21481 taacttcaac cagtgaagac caaatgcgtg gtgatcaaaa tattcaaacg agtcttttag
    21541 agtctgtttt gcattacagc aagggggcag ctaaagctca gctagatggg gcggtttgtt
    21601 cggcacaaga agtagaagct atcaaggcgg tgacgcctac gggatttact tgcttaactc
    21661 ctggcattcg tcctaaaggc agtaatattg gcgatcaaaa acgagtgatg actccaaacc
    21721 aagcaagacg cattggaagt gattatattg tggtagggcg accaattacc caggcaaaag
    21781 acccagtggc tgcttaccaa gccataaaag ctgagtgggc aggctaacag ataagattag
    21841 gaaaccaaca cttgtctgtt aaagaagaaa aaggagaata agaaatgaca ctagcaagcc
    21901 aaattgcaac tcaattactt gatattaaag ctgtttattt aaagcctgaa gaccctttta
    21961 cgtgggcatc tggcattaaa tcacctattt acactgataa tcgtgtcacc ctttcttatc
    22021 ctaagactcg tgatttaatt gagaatgggt ttgtggaaac tatcaaggct catttcccag
    22081 aagttgaggt catcgctggt acagctacag caggtattcc tcacggtgcc attatagcag
    22141 ataaaatgac tcttcctttt gcttatattc gcagtaagcc aaaagatcat ggagcaggca
    22201 accagattga ggggcgtgtg cttaaaggcc aaaaaatggt tatcattgaa gatttgattt
    22261 caacaggtgg ttcggtacta gatgcagccg cagcagccag tcgtgaggga gctgacgttc
    22321 tgggagttgt tgcgattttc acttatgagt taccaaaagc tagtcagaat tttaaagaag
    22381 ctggtatcaa gttgattacg ctttctaatt atactgagct aattgcagtt gcaaagttgc
    22441 aaggctatat tactaatgat ggtttacatt tacttaaaaa atttaaagaa gaccaggtaa
    22501 actggcaaca ataaggaact atcagccagg tttattttta atgaaaaaat ctctttagcc
    22561 ccaattcaaa atgttatgtt ttgattgttt tgtctacatt ccttacacat cacattctaa
    22621 tttctaacct tttaatggtg gttttctttt atttgtgttt taataaaaaa gaatgtttta
    22681 ggattcatat cttagaaagg aagagtagct atgacttatc aagatgcgac ggctatggct
    22741 attgctgttc agactggtca gaccacacca ctagaattag taacccaggc tatttataag
    22801 gctaaaaagt tgaaccctac cttaaatgct attacctcag aacgctttga agcagcccta
    22861 gaagaagcca aacaaaggga tttttcaggt ctgccttttg ctggtgtgcc tcttttttta
    22921 aaagatttgg gacaagaatt aaaaggtcac tcatcaacct caggttccag attgtttaaa
    22981 gagtatcaag cgactaaaac ggatttattt gtgaaaagat tagaagcttt aggctttatt
    23041 attttagggc gctccaacac gcctgaattt ggctttaaaa atattagcga tagcagtttg
    23101 cacggaccag tgaatttacc aagggataat acacgaaatg ctggtggctc atctggggga
    23161 gctgctgctc tagtgtcatc aggaattagt gcgctagcaa ctgctagtga tggtggtggt
    23221 tctattcgaa ttccagcctc gtttaatggc ttaattgggc tcaaacctag ccgtgggcgc
    23281 atgcctgtcg gacctggttc ttatcgaagc tggcaaggag cctcagttca ttttgccttg
    23341 accaaatccg ttagagatac tagaaatcta ctctactatt tacagatgga acaaatggaa
    23401 agccccttcc ccctagccac cttaacaaaa gatagtattt atcaatcgct acaacgtccc
    23461 ttgacaattg ctttttatca acggttaagt gacggtagcc cagtatcttt agatactgca
    23521 aaagctttaa gacaagcagt aacttggcta agagaacaag ggcatcagct agttgaattg
    23581 gaagagtttc ctgtaaatat gacagaagtg attcgtcatt attatattat gaatagtgtg
    23641 gaaacggctg ctatgtttgc tgatattgaa gacacttttg gacgtccgat gaccaaagac
    23701 gatatggaaa ccatgacctg ggctatttac caatcaggta aagacatccc agcttggcgt
    23761 tactcacagg tccttcaaaa atgggatacg tacagtgcaa ccatggctag ttttcatgag
    23821 acttatgacc tgttgttgac gttcacaacc aacacaccag ctcctaagca cggagaactt
    23881 gtcccagatt cgaaactcat ggctaacttg gctcaagctg aaattttcag cagtgaagag
    23941 caattcaatt tggtcgaaac catgtttggt aagagtctgg ctattaatcc ttacacagct
    24001 ctgcctaatc taactggcca gccagctatt agtttaccta cttatgaaac taaggaaggt
    24061 ctctcaatgg gcattcaact aattgcagcc aaaggtagag aggacctatt attaggaatt
    24121 gcagaacagt ttgaggcagc aggattattg aagattcctc aataataatc ttataaaaca
    24181 gtttaactat tatagattaa ctttttaaag agattgagtg ctcactgata acacaactta
    24241 atcaaaatgt tatactattc ttatcttaat aaaggagtta ctatgaagaa atcagttaca
    24301 ttactgtcta tcggacttgc cagcctttta ttggcagcat gtgcgccaca tcaatctcaa
    24361 aaatcaagtt gggacactat caaagaaaaa ggggtgttaa aagtagctac cccaggaacc
    24421 tatcagccaa cttcttttta caacgataat aatgagttag taggttacga agtagatatg
    24481 gtcaaagaaa tcggtaaacg acttaacatt aaagtcaagt ttgttgaaac aggatttgac
    24541 caagccttta cctcagttga tagtggtcga gtggatattt ctttgaacaa ctttgacatt
    24601 accccaaaac gtcagaaaaa atacaatatc tctacgcctt ataaatacgg ggtaggaggc
    24661 atgattgtcc gtgctgatgg cagctcaaac atggctaaaa aagatcttag cgactggaaa
    24721 ggaaaaaaag cagccggcgc ttctggaaca gaatacatga aagtagcgca aaaacaggga
    24781 gctgaactgg tgacctacga taatgttaca ggagatgttt atctaaacga tgtggctaac
    24841 ggtcgaacag atttcatccc aaatgattac ccagctcaaa aattatttgt ggattacatg
    24901 ttatctcaaa atccaaatct aaatgtcaaa atgagcgatg ttcagtacaa cccaaccgaa
    24961 caaggaattg ttatgaacaa aaaagacgat agcctcaaga aaaaaataga tgctgttatt
    25021 aaagacatga taaaagatgg tagcttgaag aaaatctctg aaacctacca tgctggtcaa
    25081 gatctgacaa aaccttttgg caaagacaaa aaaattcccg tcattgatac gaaagacgtt
    25141 aactaatact tgatgttaaa ggagtcctaa ccacatgatt aatatcccat taatgaaaga
    25201 tagtttagga tttgtgttat cgggattacc ttataccctt ggtatttcgt tgctcagttt
    25261 ttttacgggt ctgtttttag gtttaggcct agcccttctg ggaaggtcac gtcagccgtt
    25321 gattcattat cttgttagag cgtacatctc tattatgcga ggtgtgccga tgatcgtggt
    25381 gctctttgtt ctttatttcg ggttgcctta ttatggttta gaattgccag ctttactttg
    25441 cgcttatctt ggtttttcta tggttagcgc tgcctatatt tctgaagttt ttcgctcttc
    25501 tatagaagct attgacaagg gacaatggga agcagctaag gctttagggt tgccatatgc
    25561 tcttatggtt aagaaaatta ttcttcctca agcctttcga attgcagttc ctcctttagg
    25621 aaatgtcatt attgatatgg ttaaaagttc gtcgctagct gccatgatta ccgtaccaga
    25681 tatttttcaa aatgccaaaa ttattggcgg tagagagtgg gattacatgt ccatgtatat
    25741 tttagtagcc tttatctatt ggcttattgc ttttttgtta gaacgttacc aagaattctt
    25801 agaaaataag ctagcacttg tttaatatcc tgtaaaaaac gaatattaac cctggaaata
    25861 tcatattttc agggtctttc tatttaaaat gtggtaaact agatagaaaa ggacatcgta
    25921 tttaacttag aaactgacgt gattagaaag gaatcttatg gctcattcaa tttggcatga
    25981 gaaaatcaaa tcatttttgc cggagcatta ctacggtcgc atcaatcact ttttagatga
    26041 agcctatgct tccggtcttg tctatcctcc acgagaaaat gtctttaaag ccttacaagt
    26101 cactcctttg gaagaaacca aagtgttgat tttaggacaa gacccttatc atggccccaa
    26161 acaggcccag ggcttatcat tttcagttcc agaagagatt tctgctccgc catcccttat
    26221 taatatttta aaagaattag cagatgacat tggtcctcgt gaccatcatg atttaagcac
    26281 ttgggctagt caaggggttc tgcttttgaa tgcttgctta acagtgccag caggccaggc
    26341 taatgggcat gcaggcttaa tatgggagcc atttacagat gctgttatta aagtgctgaa
    26401 tgagaaagac agccctgtag ttttcatttt gtggggagct tatgcaagga agaaaaaagc
    26461 cttcattact aatccaaagc accacatcat cgagagccct catccaagcc ctttgtcatc
    26521 ttatcgtggc ttttttggca gcaaaccctt ttcaagaacc aatgctattt tagaaaaaga
    26581 gggcatgact ggcgtagatt ggctaaaata agccagccat ttcaactaaa tagcttaatc
    26641 tagacatttt gataccttta ataagtgaaa tgagtgcagt agatttttcc tattaaagaa
    26701 cgtaaggtct tatggttaaa acagataaat aaaggagaaa acatgatact catcaaaaat
    26761 ggacgcgtta tggacccgaa atcgcagaga gatcaagtgg cagatgtctt gattgatggt
    26821 aaacagattg taaagatagc ttcagctatt gaatgccaag aagctcaagt gattgatgct
    26881 agtggtctta ttgttgcccc gggtttggtc gatattcatg tgcattttag agaacccggt
    26941 caaacgcaca aagaagatat tcacacggga gccttggcag cagcagcagg tggtgtgact
    27001 acggttgtca tgatggctaa taccaatcct gtcatttcag atgtcgaaac tttacaggaa
    27061 gtgctagcta gcgcagctaa agaaaagatt catatttaca ccaatgccag tgtcacccaa
    27121 gcctttaatg gaaaagacgt gactgatttt aaagctttgt tggaagcagg agcagtaagc
    27181 ttttcagatg atggtattcc cttagaaagt tctaaagttt taaaagaagc ctttgatttg
    27241 gctaatgcca accaaacttt catttctttg catgaggaag atcctcagtt aaatggggtt
    27301 cttggtttta atgaaggtat tgctgaggag cattttcatt tttgtggggc aactggtgta
    27361 gcagaatata gtatgattgc aagagatgtc atgattgctt atgacaggca agctcatgtt
    27421 catatccaac atttatctaa agcagaatcg gttcaagtag tggcttttgc tcagcagttg
    27481 ggtgctaagg taactgctga agtgtcccca caacattttt caacaactga agatctctta
    27541 ttgatcgcag gtaccagcgc caagatgaat cctccccttc gtacacaaag agatcgctta
    27601 gctgtcatag aaggcttgaa atcgggtgtt atcacagtca ttgccactga tcatgctcct
    27661 catcacaagg atgaaaaagc tgtggatgat atgactaaag ccccatctgg tatgacagga
    27721 cttgaaactt ctttgtcatt aggtttgacg catttggttg aaccaggtca tcttacactt
    27781 atgtcactat tagaaaaaat gacgcttaat ccagctttgc tttatggttt tgatgcgggt
    27841 tatttggcag aaaatggtcc agcagatttg gttatttttg cagacaagca agaacgtctg
    27901 atcactgaga attttgcttc taaagctagt aattccccat ttattggtaa caaactcaaa
    27961 ggtgtcgtga aatacactat tgcagacgga gaggttgttt accctaatta acaaatgagt
    28021 taaaacaaaa aagcttgact ttcagagaaa gtcaggcttt tagtaaattt attttttagg
    28081 cacttgtttg cttaaattta gcccccaagg tattagattt tcagtatgat gtttgatacg
    28141 actaatgtta tctttgtgtc ttataataat aatgaacgca agtaatatca caataaaagt
    28201 taaaaagtag tcataatttg gtaaaagaaa atgaatggca ggaaatgtta aaacagataa
    28261 cacaccaacg atagctgaaa ccacactagc taaagatatc atactaaata aatagagaac
    28321 taaaacaaag atagatgcta aaaaaaagag atataacgga gcaaagccta gcaatacacc
    28381 agcacttgtt gctacggcct taccaccttt aaagttggca aaaataggaa aagtatgccc
    28441 taaaactgcg aaaaagccga tagcaatgga tgaaattgaa gtcataccaa aaataattgg
    28501 taacaatatt gaaagtgtcc ctttaaacat atcaatagct aaggtagctg ttcctgcctt
    28561 gacacctaaa atccgaaaag tatttgtggt tccagtattt cctgatccat gctctcgtaa
    28621 gttgatgtgg taaaagtact gtccaatcca tagtccagtt ggaatagaac caagtaaata
    28681 ggcaatggta ataaaaagta gtaatttcat aatccttatt ataacatatt catagattgg
    28741 agaactagat ctggaaaaga attcggaaaa aattagcaaa ttattttgca aaattggtaa
    28801 aaaacttgta agataaaaaa gatgaaactg tctggaggtc ggtgttgact aagaaagaaa
    28861 ttacaattaa taattataat gacgatgcta tccaagtcct agaagggtta gatgctgttc
    28921 gcaagcgtcc agggatgtat atcggttcaa cagatgctac gggattgcac cacctgattt
    28981 gggaaattgt tgataatgct gtcgatgagg ccttgtctgg ttttggagat gatattaagg
    29041 ttgttatcaa taaagatggc tcggtcagtg tggcagatag cggacgtgga atgccaacag
    29101 gccagcatgc catggggatt cccaccgttc aagttatttt tacgattctt catgcaggtg
    29161 gtaaatttgg tcagggtggc tacaaaacgt caggtggttt gcacggtgtt ggctcctctg
    29221 ttgtcaatgc tttgtctgcc tggttagaag tcgaaatcac aagagacggg tcagtgtatc
    29281 gtcagcgctt tgaaaatggt gggaaacctg ttacaaccct taaaaaagtt ggcacagctc
    29341 ctaagtctaa atcaggaacg gttgtaacct ttatgcctga tgataagatt ttttcaacta
    29401 ttgactttaa gttcaatacc atttcagaac gattgaaaga atctgctttt cttttgaaaa
    29461 atgtcaagat gagcttgaca gatcttcgtg gagatgaccc gattattgaa gagtttcatt
    29521 atgaaaatgg ggttcaagat ttcgtcgaat acctcaatga agataaggaa accttgacac
    29581 ctgttattta catggaaggt caagaccaag actttcaagt cgaggttgct ttgcagtata
    29641 acgatggttt ctccgacaat atcttatcct ttgtaaacaa tgtgcgcacc aaagatggtg
    29701 gaagccatga aacgggacta aagtcagcta ttaccaaagc gatgaatgac tatgctcgta
    29761 aaaccaatct cttaaaagaa aaggataaaa atctagaggg ctcagattat cgagaaggac
    29821 tctcagcagt attatctatc ttagttcctg agcagcactt gcaatttgaa ggacagacca
    29881 aagacaaatt gggaagtcct ttagctagac ctattgtaga gagcattgtt tctgaaaaat
    29941 taaccttctt tttactcgaa aatggagaag tagcttctca tctagttcgc aaagccatta
    30001 aagctagaga tgctcgcgaa gctgctcgaa aagcgcgtga tgactcacgt aatggtaaga
    30061 aaaacaaaaa agacaaaggc ttgttgtcgg gaaaactaac cccagctcag tccaaaaatg
    30121 ccaagaaaaa tgaattgtat ctggtcgaag gagattctgc gggaggttca gccaaacaag
    30181 gacgagaccg caaatttcag gctattttac cattacgtgg caaagtttta aataccgaaa
    30241 aagctaagat ggctgacatc ttgaaaaatg aagaaattaa cactatggtt tataccattg
    30301 gagctggagt gggagctgac tttaacctcg aggatatcaa ctatgataag attattatca
    30361 tgaccgatgc tgataccgat ggggctcata ttcagactct tttgctgact ttcttttacc
    30421 gttatatgcg accgttggtg gaagcaggtc acgtttatat tgcgcttccc ccgctttaca
    30481 aaatgtcaaa aggtaaaggc aaaactgaaa aaattgctta tgcttggact gatggtgaat
    30541 tggaagatct gcgcagagaa tttggcaagg gggctattct tcaacgctat aaaggactgg
    30601 gtgaaatgaa tgctaaccaa ttatgggaaa ccactatgga ccctgaaacc agaaccctta
    30661 ttcgtgttac tattgacgac ttggcaagag cagagcgacg tgtttctgtg ttgatgggtg
    30721 acaaagcagc cccacgccgt cagtggatcg aggataacgt caagtttacc ttagaagaaa
    30781 atacggtgtt ttagtcatac aagtttctca cagataatta caagtgctaa agacgattgt
    30841 tttttaggta attaataaat aatgaaaaag aaagctattt gaatatgtca aacattcaaa
    30901 acatgtccct tgaggatatt atgggagaac gcttcggccg ttattccaag tatattattc
    30961 aggaacgggc acttcctgat attcgagatg gattgaaacc cgttcagcgt cggattcttt
    31021 attcgatgaa taaggatggc aatacttttg aaaaaggtta ccgtaaatca gccaaatcag
    31081 ttggtaatat tatggggaat ttccacccac atggggattc ctctatttat gatgccatgg
    31141 tacggatgag tcaagattgg aagaaccgtg aaatccttgt tgaaatgcac ggaaataatg
    31201 gttcaatgga tggtgatccg cctgcggcta tgcgttatac agaagctcgc ttgtctgaaa
    31261 ttgcgggtta tcttcttcaa gacattgaga aaaatacggt ctcttttgct tggaactttg
    31321 atgacacaga aaaagaaccc accgttttac cagcagcttt tcctaactta cttgtcaatg
    31381 ggtcttctgg tatttccgca ggctatgcga cagatattcc accgcacaat ttgtcagaag
    31441 tgattgatgc tgttgtgtat atgattgatc atcccaaagc tagtttagag aaattaatgg
    31501 agtttttacc aggaccagat ttcccgacag gaggcattat ccaaggagct gacgaaatca
    31561 aaaaagccta cgaaacaggt aagggacgtg tcgttgttcg ctctaggaca gaaatcgagg
    31621 aacttaaagg tggtaaacaa caaattattg tcactgagat tccttatgaa gttaacaaag
    31681 cagtcttggt caaaaagatt gacgatgtgc gtgttaacaa taaagtccca ggcatcgtag
    31741 aagtacgcga tgaatctgat cgcacaggtc ttcgcatagc tattgagttg aaaaaagagg
    31801 ctgatagcca aaccattcta aattatttgt tgaaatacac agaccttcaa gttaattata
    31861 attttaacat ggttgctatt gaccacttca caccacgtca agtaggactt caaaaaatac
    31921 tatcaagcta tatcagtcac cgtaaagata ttattattga gcggtctaaa ttcgataaag
    31981 ccaaagctga aaaacgcctc cacattgttg aaggattgat tcgtgtcttg tccatcttag
    32041 atgagattat tgctttgatt agatcgtctg acaataaggc tgatgctaaa gaaaatctga
    32101 aagtcagcta tgatttctct gaggaacaag cagaagcgat tgtaaccttg cagctttatc
    32161 gtttaactaa taccgatatt gttactctcc aaaatgaaga aaatgattta agagacttaa
    32221 tcacgaccct ttccgctatt atcggtgacg aagcaaccat gtataacgtc atgaaacgtg
    32281 aattaagaga ggtgaaaaag aaattcgcca atcctcgttt atcagagtta caagcagaaa
    32341 gtcaaatcat tgagattgac actgccagct tgattgcaga ggaagaaact tttgttagtg
    32401 tgacacgggg cggatacctc aaaagaacca gcccacgatc cttcaatgcg tctagtttgg
    32461 aagaagttgg caagagagat gatgacgaac tcatcttcgt taaacaggcc aaaacaacag
    32521 aacacctttt gttatttaca actttaggca atgtcattta ccggccaatc catgaattga
    32581 ccgatttacg ttggaaggat atcggtgaac atttatcaca aaccatttca aacttcgcga
    32641 cagaagaaga gattctctac gctgatattg tgacttcctt tgaccagggc ttgtatgtgg
    32701 ctgtcacaca aaatggtttt atcaaacgct ttgatcgtaa agaactaagt ccttggcgaa
    32761 cttataaatc taaatcaacc aaatatgtga agctaaagga tgacaaagac cgcgtggtta
    32821 ccttgtcacc agttattatg gaagacctcc tattagtgac taaaaatggt tatgctttgc
    32881 gattctccag tcaggaagtg cctattcaag ggttgaaatc tgctggtgtt aaaggcatta
    32941 acttgaaaaa cgatgacagc cttgcctcag cctttgctgt gacaagtaac tctttctttg
    33001 tcttaactca gaggggttct ctcaaacgga tggctgtcga tgatattcct cagacaagtc
    33061 gtgccaatcg tggactattg gtcctacgag agttaaaaac caaacctcat agagtttttc
    33121 tggccggagg cgttcaatca gatacttcag ctgagcagtt tgatttgttc actgatatac
    33181 ctgaagaaga aactaatcaa caaatgcttg aagtcattag taagactggt caaacctacg
    33241 agattgcttt agaaacgctt tcgttatcgg aaagaaccag caacggctcc tttatttcag
    33301 acactatttc ggatcaagaa gtactggtag ctagaacacg ttaaaaagag tgaaaactct
    33361 ttttaatttt atgataaatt tagaatatta atacaaaaga atagaataaa cttgaaaatt
    33421 attgaaaaaa agttacaata gaaaaaagca gaaaagaggt acgatgatga caatagcaat
    33481 tgattgggac aacctaggat ttgaatatca taagttgcca tttcgttaca tttcttatta
    33541 caaaaatggt caatgggata aaggtcaatt aacagaagat gccaccttac atatctcaga
    33601 aagcgctcca gcgcttcatt atggacaaca agcttttgaa ggcttaaagg cttatcgcac
    33661 caaagatggc tctattcaac tatttagacc agaccgtaat gcagtgcgtt tacaagccac
    33721 agcagaccgc ttgttgatgc cacaagtatc aacagagcaa tttattgatg cagctaagca
    33781 agtggttaaa gccaatgaag actttgtacc accttacgga acaggtgcaa cgctttacct
    33841 gagaccgtta ttaattggag ttggagatat tattggggtt aaaccagccg aagaatatat
    33901 tttcaccatt tttgccatgc cagtaggaaa ctatttcaaa ggtggacttg ctccaactaa
    33961 ttttattgtt tctgaagcgt ttgaccgcgc cgctccttac ggaacaggtg ctgctaaggt
    34021 gggaggaaac tatgcaggaa gtttgctacc aggtaaggcc gctaaatcag caggcttttc
    34081 tgatgtgatt tacttagatc cagcaaccca tactaaaatt gaagaagtcg gagctgcaaa
    34141 cttttttggc attactgcaa ataatgaatt tgttacgcca cttagtccat ccatcttgcc
    34201 atctattacg aagtattcac tcttacaact agctgaagaa agacttggta tgacagtaat
    34261 tgagggtgat gttccaatta atgaattgga taaatttgtg gaagcaggag cttgtggaac
    34321 agcagctgtt atctctccaa ttggcggtat ccagtacaag gataacttac atgtctttta
    34381 cagtgaaaca gaagttggtc ctgtgacacg ccgtttatac gatgagttgg tcggcattca
    34441 atttggggat attgaagcac cagaaggttg gattgtaaaa gtagattaaa atagagcttg
    34501 ctcttgcaag cttttttgat tttgtgtaaa atagacaaag tgaggtaaag tgatgagtaa
    34561 aaaagataaa aaaattgaaa tccaactgat tgatcacaaa gttatggtta atgagactaa
    34621 gattgatggc tatcaattac aaattggtaa acgtgtggtt ggagaaattg cagaacttga
    34681 tgagaaattt gctgtcttaa aaaatgatgg agtagattgc ttcttcaaaa cgctcgaaca
    34741 agcggttgaa aatatcattg aaaactacaa tttgaaccat taaaattaga caaaaacact
    34801 tgccagctta caaaaactat gatagaatag tttttgttgt tacggaaaga tagcgaagag
    34861 gctaaacg
//
LOCUS       DAUGJR010000017        33688 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUGJR010000017 DAUGJR010000000
VERSION     DAUGJR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33688
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.017"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..376
                     /locus_tag="VH800_000837"
     CDS             <1..376
                     /locus_tag="VH800_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8361916.1"
                     /translation="ALSYGITNLFPLYVCFFFFVYISNASKITINIVEKMGIIFVISA
                     IIGATVLAMYLTWTPVGSSTVLGVQSRYLIGIIPLVLLLFSSQQQKFKQIEDILSDKL
                     AIHVSLLFILAMLMSTIFRYYH"
     gene            470..1693
                     /gene="pepT"
                     /locus_tag="VH800_000838"
     CDS             470..1693
                     /gene="pepT"
                     /locus_tag="VH800_000838"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEQ8361917.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSVPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKDRPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            1734..2222
                     /locus_tag="VH800_000839"
     CDS             1734..2222
                     /locus_tag="VH800_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEQ8361918.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(2209..2406)
                     /locus_tag="VH800_000840"
     CDS             complement(2209..2406)
                     /locus_tag="VH800_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEQ8361919.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            2455..2931
                     /locus_tag="VH800_000841"
     CDS             2455..2931
                     /locus_tag="VH800_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8361920.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            2946..3626
                     /locus_tag="VH800_000842"
     CDS             2946..3626
                     /locus_tag="VH800_000842"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEQ8361921.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWI
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    3650..3773
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            3788..4318
                     /gene="infC"
                     /locus_tag="VH800_000843"
     CDS             3788..4318
                     /gene="infC"
                     /locus_tag="VH800_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEQ8361922.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            4360..4557
                     /gene="rpmI"
                     /locus_tag="VH800_000844"
     CDS             4360..4557
                     /gene="rpmI"
                     /locus_tag="VH800_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEQ8361923.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            4616..4975
                     /gene="rplT"
                     /locus_tag="VH800_000845"
     CDS             4616..4975
                     /gene="rplT"
                     /locus_tag="VH800_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEQ8361924.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(5266..7476)
                     /locus_tag="VH800_000846"
     CDS             complement(5266..7476)
                     /locus_tag="VH800_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEQ8361925.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIA
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPKNKE"
     gene            7584..8747
                     /locus_tag="VH800_000847"
     CDS             7584..8747
                     /locus_tag="VH800_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEQ8361926.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            8744..9430
                     /locus_tag="VH800_000848"
     CDS             8744..9430
                     /locus_tag="VH800_000848"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEQ8361927.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            9524..10690
                     /gene="aroC"
                     /locus_tag="VH800_000849"
     CDS             9524..10690
                     /gene="aroC"
                     /locus_tag="VH800_000849"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEQ8361928.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            10751..11092
                     /locus_tag="VH800_000850"
     CDS             10751..11092
                     /locus_tag="VH800_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEQ8361929.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADVSASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            11313..12665
                     /gene="gorA"
                     /locus_tag="VH800_000851"
     CDS             11313..12665
                     /gene="gorA"
                     /locus_tag="VH800_000851"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEQ8361930.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEM
                     AVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTG
                     VTLNDKGYIETDVYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(12753..14021)
                     /locus_tag="VH800_000852"
     CDS             complement(12753..14021)
                     /locus_tag="VH800_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8361931.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(14051..14491)
                     /locus_tag="VH800_000853"
     CDS             complement(14051..14491)
                     /locus_tag="VH800_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8361932.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITISRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTTPSHNETTPTAPETPSATEGTQIPNATGAEDANTGLPTNP"
     gene            14726..15868
                     /locus_tag="VH800_000854"
     CDS             14726..15868
                     /locus_tag="VH800_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8361933.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKNAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKSLS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            15880..17094
                     /gene="thiI"
                     /locus_tag="VH800_000855"
     CDS             15880..17094
                     /gene="thiI"
                     /locus_tag="VH800_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEQ8361934.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGTGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            17132..18424
                     /locus_tag="VH800_000856"
     CDS             17132..18424
                     /locus_tag="VH800_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEQ8361935.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    18529..18603
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            18638..18952
                     /gene="rplU"
                     /locus_tag="VH800_000857"
     CDS             18638..18952
                     /gene="rplU"
                     /locus_tag="VH800_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEQ8361936.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            18964..19290
                     /locus_tag="VH800_000858"
     CDS             18964..19290
                     /locus_tag="VH800_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEQ8361937.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            19318..19611
                     /gene="rpmA"
                     /locus_tag="VH800_000859"
     CDS             19318..19611
                     /gene="rpmA"
                     /locus_tag="VH800_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEQ8361938.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            19958..20872
                     /locus_tag="VH800_000860"
     CDS             19958..20872
                     /locus_tag="VH800_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8361939.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            20869..21327
                     /locus_tag="VH800_000861"
     CDS             20869..21327
                     /locus_tag="VH800_000861"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEQ8361940.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLLICLWKEEDYGN"
     gene            21317..22207
                     /locus_tag="VH800_000862"
     CDS             21317..22207
                     /locus_tag="VH800_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8361941.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            22603..23124
                     /gene="pyrR"
                     /locus_tag="VH800_000863"
     CDS             22603..23124
                     /gene="pyrR"
                     /locus_tag="VH800_000863"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEQ8361942.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            23140..24399
                     /locus_tag="VH800_000864"
     CDS             23140..24399
                     /locus_tag="VH800_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEQ8361943.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            24460..25395
                     /locus_tag="VH800_000865"
     CDS             24460..25395
                     /locus_tag="VH800_000865"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEQ8361944.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            25439..26521
                     /gene="carA"
                     /locus_tag="VH800_000866"
     CDS             25439..26521
                     /gene="carA"
                     /locus_tag="VH800_000866"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEQ8361945.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            26747..29923
                     /gene="carB"
                     /locus_tag="VH800_000867"
     CDS             26747..29923
                     /gene="carB"
                     /locus_tag="VH800_000867"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEQ8361946.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSPLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            30130..31401
                     /locus_tag="VH800_000868"
     CDS             30130..31401
                     /locus_tag="VH800_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8361947.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGIVLWKQQRNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNRDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGATYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            31401..32111
                     /locus_tag="VH800_000869"
     CDS             31401..32111
                     /locus_tag="VH800_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361948.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            32123..33343
                     /locus_tag="VH800_000870"
     CDS             32123..33343
                     /locus_tag="VH800_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361949.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGKGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
BASE COUNT        10677 a         5634 c         7087 g        10290 t
ORIGIN      
        1 cgcattaagc tatggtataa cgaacctttt cccgctttat gtgtgtttct tcttttttgt
       61 ttatattagt aatgctagta aaataactat taatattgta gaaaaaatgg gtataatctt
      121 tgttatttca gcgattatag gtgcaactgt attagctatg tacctgactt ggacaccagt
      181 agggtcctca actgtcttag gtgttcaaag tcgttatctg ataggaatta tcccattagt
      241 gttgcttctt tttagtagtc aacagcaaaa gttcaaacaa atagaggata tcctttctga
      301 caaactggct attcatgttt cgcttttgtt tattcttgca atgttaatga gtactatttt
      361 tagatattat cattaaactc ttaattagag gctttaaaaa acttagcttg aataagtatt
      421 ttaaagcctt ttatgctata attaaattga gaaattattg aggtggccta tgaagtacga
      481 taacttgtta gatcgattta taaaatatgt caaagtgaat acaagaagcg ttccagacag
      541 tgagactact cctagtacgg agagtcaaga agcatttgcc ttaacgattt taaagcctga
      601 aatggaggca attggtttgc aagatgttca ttataatcca gttaatggct atcttattgg
      661 aactctgcct gccaataatc caaccttgac gcgtaaaatt ggttttatag cccatatgga
      721 tacggctgat ttcaatgctg aaaatgttaa tccgcagatt attgacaatt atcaaggagg
      781 ggacattaca cttggcagtt ctaattataa gttggatcca aaagcatttc caaatcttaa
      841 taattatatc ggtcaaacat tgattaccac tgatgggact acacttttag gggcagatga
      901 taaatctggt attgctgaaa tcatgacagc aatagaattc ttgacatcac aaccacaaat
      961 agagcactgt gacattaaag tggcttttgg ccctgatgaa gagattgggg tcggagctga
     1021 taagtttgag gtggctgatt ttgaggtgga ttttgcttat actatggatg gcggtccttt
     1081 aggcgaattg caatatgaaa ctttcagcgc tgcagctcta gaagtgactt ttttaggcag
     1141 aaatgttcat cctggtacgg ctaaggatca aatgattaat gcccttgagt tagcaataga
     1201 ttttcatgag aagctacctg ctaaagatcg gcctgaatac acagatggtt atcaaggttt
     1261 ctatcactta acgggactaa ctggaacagt tgaagaggca cgcgcatctt acattattcg
     1321 tgattttgaa gaagcatcat ttgaagctag aaaagtgaaa gttgaaaata tagctcaatc
     1381 gatgaatgct cagctaggaa caaaacgtgt cttggtagag cttaatgacc aatactacaa
     1441 tatgaaaaaa gttatcgaaa aagatatgac cgctattgag ttagctaaag aagtaatgga
     1501 agagcttgct atcaagcctg taatcgaacc catacgtgga ggaacagatg gctctaaaat
     1561 ttcatttatg ggtattccca ctcctaatat ttttgcaggg ggtgagaata tgcacgggcg
     1621 ttttgagttt gttagcttac aaacgatgga gagagctgtc gatgtcatta ttggacttgt
     1681 ttgcaaagcc taattatcat ggaattgata tttagtggaa ggggcttata aaaatgatta
     1741 aactatttgg taaaataagg tatcactggc agccagagtt gtcttggtct attatttatt
     1801 ggtctattgc gtttgcacct atttttgtag gtttatcttt gttgtatgag cgcactgaaa
     1861 tacctagtcg ggtttttatt ctatttgcta tttttgctgt cctagttggc attggattac
     1921 atcgttattt cattattgaa aataatggta ttttaagaat cgtatctttt aaattgtttg
     1981 gtccacgtaa gctacttatt tccactatta ctaagattga ggtgaccaaa tcaacacttt
     2041 gtctgcacgt tgaagataaa agttatctct tttatatgcg caaatggcct aaaaaatatt
     2101 ttcttgatgc cttagcggtt aatccatact tccaaggaga agttatatta agtgataact
     2161 ttattaaatt agactatttt gaagtttatc agcatgataa aaaagccctt actcgagggt
     2221 aagagcttta gttgggcaag atttgacagc taaaatagcg tccttatctg aaggacaaat
     2281 tgactgactt gtttcagatg agcttgaaaa tgtgacgata ccattgtcat gataatcaaa
     2341 aagtgatgaa taggtttggc atagaccaca agcgatgcat ttttctggaa tgatagatac
     2401 tttcataact attattctaa tatgattttg ttaaattaac aaggggggac gatcatggct
     2461 aaagaaccat gggaagaaaa aattgttgat gatactatag ggacacgaac acgtaaatca
     2521 agaaatgctt tcattagcac gccttggttg actgctttat taagtgtatt ctttgtcatc
     2581 attgttgcta tactttttat tttcttctat acatcaaata gcggtagtaa tagacaagct
     2641 gaaacaaatg gtttttatgg agcatccact cataaaaaaa caaggaaagc ttctaacgct
     2701 aaaaaaacat caagtagttc aacaactaca gacacaacac cttctagcga agaaacactt
     2761 gcttctagtg aaggaactgg cgaaaccctt actgtattgg caggtgaggg ggcagcttct
     2821 attgcagctc gtgcaggtat ttctgtggag cagttacaag cacttaatcc agagcacatg
     2881 actcaaggat attggtatgc caatccagga gatcaagtca ctattaaata attgaagagg
     2941 aaaaaatgaa agcaattaaa attgcgattg atgggccagc ttcaagtgga aaaagtacag
     3001 tagccaagat tattgcaaaa aatcttggct atacttatct agatactggt gctatgtatc
     3061 gctcagcaac ttatatcgca ctgacacatg gctatacggg taaagaagta gcccttatct
     3121 tagaggaact tgagaaaaat cctattttct ttaaaaaagc aaaagatggc tcccaattag
     3181 tttttcttgg ggatgaggac gtgaccttag ccattaggca aaatgatgtg actaacaatg
     3241 tttcttggat ctcagctttg ccagaaatta gagaagagct ggttcatcaa caaagacgca
     3301 ttgcacaagc tggtggcatt atcatggatg gtcgtgacat tggaacggtt gttctcccag
     3361 atgcggaact aaaaatcttt ttagtggctt ctgtcgaaga gcgggcagag cgccgctata
     3421 aagaaaacct agaaaaagga attgaatcag attttgagac gctaaaagaa gagattgcag
     3481 ctcgtgatta caaggatagt catcgtaagg tttcacctct aaaagcagct gaagatgccc
     3541 ttatttttga taccacaggt gtttctattg atggcgtggt gcaatttatc caagaaaaag
     3601 cagaaaaaat agttgacatg tcctagagcc tatgttagaa tagtaacaat gagaaaagta
     3661 gaagtgagag cttctcgcct tgcgacttag gttgtctggc cctaacatgt caaattccta
     3721 tggaatatta tgtgtgcggg cttgatttat caagtccgct ttcgtttttc tctaaaaaaa
     3781 taaagaggtg aagatcatag ctaaaaagga tctattcatt aatgatgaaa ttcgcgttcg
     3841 cgaagttcgt ctcgttggtc ttgaaggtga acaattaggt attaaaccat tgtctgaagc
     3901 gcaatcattg gctgatgctt caaatgttga tttggtttta atccagccac aagctgttcc
     3961 tcctgttgcc aaacttatgg actatggaaa gttcaaattt gagtatcaaa agaaacagaa
     4021 agaacaacgt aaaaaacaaa gcgttgtgac tgtgaaagaa gttcgtctca gtccagttat
     4081 cgataaaggt gactttgaaa caaaacttcg taacggtcgt aaattccttg aaaaaggaaa
     4141 taaagttaag gtttctattc gtttcaaagg acgtatgatt actcataaag agattggtgc
     4201 caaggtacta gctgactttg ctgaagcgac tcaagatatt gctatcattg agcaacgagc
     4261 aaaaatggat ggacgccaaa tgtttatgca acttgcacca atttcagaca agaagtaatt
     4321 gtcacagttt cattatatct ttaagaggag aatactaaaa tgccaaaaca aaaaacacac
     4381 cgcgcatcag ctaaacgttt taaacgtaca ggttcaggcg gtttgaaacg cttccgcgcc
     4441 tttacatcac accgtttcca cggaaaaact aaaaaacaac gtcgtcatct tcgtaaagct
     4501 ggtttggtta gctcaggaga tttcaaacgt atcaaagcaa tggttactgg tctttaattt
     4561 taaaggcagt agacatttac gagtattata agaattattt gaaggagaac tattaatggc
     4621 acgtgttaaa ggtggcgttg tttcacgcaa acgtcgtaaa cgtattttaa aattagctaa
     4681 aggttactat ggagcaaaac acatcttgtt ccgtactgca aaagagcaag tgatgaactc
     4741 ttactactat gcataccgtg atcgccgtca gaaaaaacgt gatttccgta aactatggat
     4801 cactcgtatc aatgcggctg ctcgtatgaa cggtttgtca tactcacaat tgatgcacgg
     4861 tttgaaactt gctgaaatcg aagtaaaccg taaaatgctt gctgatttag cagtagctga
     4921 tgcagcagct ttcacagctc ttgctgatgc agccaaagca aaacttggca aataagaaac
     4981 gctataccta aaaaataact ttctattacc tatagaaagt tataaagaaa caaaaatgaa
     5041 ggagacgatg gacgtcttct ttttattata ctcaatataa taaaaagcag tttcccatgt
     5101 tttattacca gtaatgtggg atatttagat ggtagcaagg agttttatag ctgatttgtt
     5161 ttctttaggt ctaattagca tattttgatt actgataaac ttgaatatcg ccaataaaaa
     5221 agaagcaaaa ttattatttt gcttctagtc agatcattaa attgattatt ctttattttt
     5281 ggggttatcc tcttttagtt cagaagttgc cgcgtcagct tctacgggat ttagttctaa
     5341 gtaagatggt gctttaaaaa gtttctgagt tgatttatga ccatttttac tgtataaact
     5401 tgttgactct gatccgagtt ttgctgaaat atctttcagt tgttttaact gcttagtgta
     5461 gataaactgg ttaggatcaa tagcttttag accattttga gtatcaaagc gcaggagatc
     5521 acccgtttga atagcgtcgc tagctgctag ttgttgagca acagcagagc gaatttcctt
     5581 agttttggct atagtcattt catcgggatt agtgatttct aaacctgttt gcgtgttgta
     5641 cagacgtcca ctatagttag tgtattcagg agtcatataa gtcccagatg ttcgttgtgc
     5701 cacaatctgg ctattttgag gtgataataa atcttgtcct aattgaacaa actgactagt
     5761 gtcaatacca agtatgtgga gtaaagtagg aagagcatcg atttcaccgc caaaggtttc
     5821 tttgatacta ccattcgtat aacctggaat atggatcata tacgggactc gttgtagcat
     5881 agcattatca tattcagacc aagtttcaga atctttacca agaagtggag caagactaga
     5941 attacgagaa tttgaaatac cataatgatc accatataaa acaaaaatag aattgtcgta
     6001 caaaccagtg gctttcaagt aatcaaaaaa agatttaagg gcagcgtcta aataattggc
     6061 agtagcaaag taaccattga tcgtttcatc gtctgttttg gctaaaggaa aaccttcttc
     6121 actactttcg ccttttagac tagtataagg atagtgatta ctcacagtga taaacttggt
     6181 ataaaaaggt tgttgcatct gttcaagata ttttatggaa tccttaaaca tgtacttatc
     6241 atttaaccca tattgaaaag agttcttact attttgttta gagaagtagc tagaatcaaa
     6301 aaaataatta tagccccatt gtttataagc attattgcga ttccagaaag ttccaacgtt
     6361 accatgaaag acagcgctgg tatagccacc tttttgggct aaaatacttg gagtagcaaa
     6421 ttgtgtattt tcaccaccgt agttcaccat aaaagaacca ctatttaaac caaataagga
     6481 attctccatc atggtttcag catcagaagt tttacctgct ttaacctgat gaaaaaagtt
     6541 agggaatgct aaggtagcat ttgagtgata aagtgagttg ataaaaggcg ttacctcata
     6601 ttctttatct ccttctttta gtttataatc tattaagaat tgttgaaagc tttctaaatg
     6661 aagaacaata atatttttgc cttttccaat tccaaaatac tgaggatcag gtgctgcata
     6721 atgtcctttg acataagttt taacatcaat taattcttct gcagtagctc catttcgttc
     6781 tttttgagct tgataggttt gattgccgct atagagggta aacgctggta gtcctaaagc
     6841 tctcacaata taagtatttg aaaagccacg tgttaatagt tccggacgat caatttctgc
     6901 taaaaaaaga ttaatagaaa gcaatagact agataaagcg gtgatggcaa atgctgcgcg
     6961 cttgttaaaa ggacgttgat catttttgat ttttttagcg atagataaac taattagaat
     7021 aataaaatca agaatataga taatatccca gatgcgtaaa aggtttaaag cagagtcccc
     7081 taatccagcg gagactttac tactagctag catggcactc actgtaataa agtctgaaaa
     7141 ttctcggtaa tatatagaat ttgatatcaa gagaatgtta aggataatat aaaccaccca
     7201 agaacagata taaaaggctc gggtattctt aacgtaaaga gcaaccccca aaagtaaaaa
     7261 agctagtggg attggattga taatagttag aaagacttgg tatatatttc ccaaatctag
     7321 tgaaaagtct gtatgatatg cccacagggt ctttatccag taacaaaaga gtagagtaat
     7381 tataaaaccc aatcttgtgt tgataaaacc tgtgataagt gttttaaatt tcttcacagt
     7441 agcaacttcc ttatcgtttt ttcctaaaga tgtcatctcc aaataaaatc tcagattaaa
     7501 ttataccaaa aatgtgaagc taatgcttgt tgtaagttca aatttagtag gattttttat
     7561 cagattttgt tataataaaa actatgaata aactctatat tgattctttt gtcgaaaaga
     7621 agctgacagc aggggtacaa ttattagatg aaaaagattt ttctaatata aaggaaaaaa
     7681 atcagttggt tcaactggtg accaagtcca atcgtcccat tggaacagca tatatctcta
     7741 agcaaaataa aggaattggt tggtatctag gaccagaaaa aatcgacttg tctatctctt
     7801 attttgttag tctattttca gttgctaagg ccaaaagaca agattttgct caatcggacg
     7861 agaccaatgc ttatcgcctt tttaatcaag aaggagacgg ttttggtgga gtaacaattg
     7921 atctttataa agattttgca gtcttttcat ggtacaatgc ctttgtctat gacaaaaaag
     7981 aaatgattat ggaggctttt caacaggttt ttcctgaagt caaaggagct tatgaaaagt
     8041 gtcgctttaa aggtccagat actgaaactg ctcatctgta tggtgagctg gcacaagaaa
     8101 ccttttcgat tttagaaaat ggcatagcct atcaagtctt cttgaatgag ggcttaatga
     8161 caggtatttt tctagaccag catgatgtta gaagagcact agtagatggt ttagctatgg
     8221 gcaagtccct tcttaaccta ttttcctata cagctgcctt ttctgtagca gctgctatgg
     8281 gtggtgctat cgagaccact tctgtggact tggctaaacg atcgagagaa ttatcactag
     8341 ctcattttga gcataaccag ttaaacttag cctcacatca ttttgtggtg atggatgttt
     8401 ttgaatactt caaatatgcc aaacggaaaa aattaatctt tgatgtgatt gtgattgacc
     8461 caccaagctt tgctagaaat aaaaaacaaa ctttctctgt gagcagggac taccacaaat
     8521 taatcacaga ggccttggac atattgagtc ctaagggaac tattatagct tcaacaaatg
     8581 ctgctaatat gactgttagc cagttcaaaa agcaaattat caaaggattt ggaagtcgtc
     8641 gtcctgagtc tatgactctc cagcagcttc cgagtgactt tactatcaat aaagcagatg
     8701 aaagaagtaa ctatttaaag gtatttacta taaaggtacg agaatgagaa ttgtagcacc
     8761 agtcatgcca agacattttg acgaggctca agccattgat atttctaaat atgaagatgt
     8821 taatttaatt gaatggcgag cagactttct tcccaaggat gagattgtcg cagtagcacc
     8881 agctattttt gaaaaatttg ccggaaaaga aattatcttt acccttcgga ccgttcaaga
     8941 aggggggaat attacccttt caagtcagga gtatgttgat attatcaaag aaatcaatgc
     9001 tatttataat ccagactata ttgactttga gtattttacg cacaagtcag tatttcaaga
     9061 aatgcttgat tttccaaatc ttattttgtc ttatcacaac tttgaagaga ctcctgaaaa
     9121 tttaatggaa gctttttcag aaatgaccaa gttggcaccg cgtgtggtta aaattgctgt
     9181 gatgccccag agtgaacaag atgttctaga tttgatgaac tataccagag gctttaagac
     9241 gctcaatcct gagcaagaat ttgcaactat atctatgggg aaattaggaa gattgtctcg
     9301 ttttgcggga gatgtcattg gctcttcctg gacatacgtt tcattagatc atgttagcgg
     9361 tccaggtcaa gtgactctca atgatatgaa acgtattatt gaggtcttag aaatggatat
     9421 ctctaactag tgaatggtct aaaaatatta tttctacaat agttaagaaa tgatgttttt
     9481 agattaatgt ttttaaaata agtggaacca aaaaggagaa aaattgcgtt atttaacagc
     9541 aggagaatct catgggccat ccttaacagc tattattgaa ggtataccag caggattaac
     9601 tcttcatcca gcggatattg atcacgaatt acagcgacgt caaggaggtt atggccgtgg
     9661 tgccagaatg tctattgaga ctgatcgggt tcaaatatcc tcaggagttc gtcatggtaa
     9721 aacaacaggg gcccccatta ccttaacggt aattaataag gaccaccaaa aatggctaga
     9781 tgtcatggct gtaggagaca ttgaagagac tctcaagtta aagcgtcgtg ttaagcatcc
     9841 tagaccagga catgcggatt tggtaggagg tattaaatat cattttaacg atttaagaga
     9901 tgctttagag cgttcctcgg ctagagaaac aacgatgaga gtggctgtag gcgctgttgc
     9961 taaacgtatc ttagctgaac ttggaattga tatgttacat catatcttaa tatttggtgg
    10021 tataacgatc acaatacctt ctaagctctc ttttagagag ctgcaagaaa gggctctcca
    10081 ttcagaatta tctattgtta atccaaagca agaagaagaa attaaaacgt atattgataa
    10141 gataaaaaaa gaaggggata ccattggtgg tattatcgaa acgatagttc aaggggtgcc
    10201 agcaggtctt ggatcttatg tccaatggga taaaaaatta gatgccaagc tggctcaagc
    10261 agttctttcc attaatgctt ttaaaggggt ggaatttgga gctgggtttg atatgggatt
    10321 ccaaaagggc tctcaggtaa tggatgaaat cacctggaca cctacccagg gctatggtcg
    10381 tcaaacaaac cacttaggtg gctttgaagg tggcatgacc acaggacaac ctcttgttgt
    10441 taaaggggtt atgaagccca ttcctacttt gtataaacca ctcatgtcgg tagatattga
    10501 tagtcatgaa ccttataaag caacggtgga acgctctgat ccgacggcct taccagctgc
    10561 aggggttatc atggaaaatg tggtggcgac ggtgcttgcc aaagagattt tagagacttt
    10621 ttcttctact accatgtctg aattgcaaaa agctttttcg gactatcgtg cctacgtcaa
    10681 gcaattttag atagcgagat actggctttt atggtatcat acaggtatta atgaacaaaa
    10741 ggagactgtc atgtcacaag aaatttatga ctatgctaat caacttgaaa gagcagttcg
    10801 tgctctgcca gaataccaaa aagtgttaga agtaaaagag gccattcaag cagacgttag
    10861 tgctagcgaa ctgtttgatg agtttgtcgc tatgcaagaa aaaatccaag ggatgatgca
    10921 atcaggccaa atgccaacgg ctgaagaaca aacaagcatt caagaactta gccaaaagat
    10981 tgaagctaat gaccagctaa aagcttattt tgaagcgcag caggccttat ctgtttacat
    11041 gagtgatatt gagcgtattg tatttgctcc gttgaaagat ttagtcaagt aagccaatta
    11101 agataggaaa aaaacagatt gctggcagct cgtcaggatc tgttttttag tgtttatttt
    11161 ctttgtatca gaaagttgag cctctttctt atttgtgata tagtcaaata aagtgaccaa
    11221 aatagcaggc cagtagtggc tttaatgaag gcaagttgtc tgctaactgg ctgtgctaaa
    11281 acatcagtat tagaaagtaa aaggtgataa aaatggttat tccttatgat tatattgtta
    11341 ttggtggagg gagtgcaggt attgcttctg cgaacagggc agccatgcat ggggccaaag
    11401 tattgttagc tgaaggtaaa gagattgggg gaacctgtgt taacctaggc tgcgttccta
    11461 aaaaagtcat gtggtatggc gctcaagtag cagatatttt agggacttac gctaaggatt
    11521 atggatttga ctttaaagag aaagcatttg attttaaaca attgaaagca aatcgtcaag
    11581 cttatattga tcggattcat gcttcttatg agcgaggctt tgagcagaat ggtgttgacc
    11641 gtatttatga ttatgctgtt ttcaaagatg ctcatacggt agaaattgca gggcagcttt
    11701 ataccgcacc gcatattttg attgccacag gaggacatcc tgtttttcca gatattgagg
    11761 gggcacaata cggtatcagc tcggacggct tttttgcctt agatgaggta ccaaaacgta
    11821 cggctgtggt tggggcaggc tatattgctg tggaacttgc tggtgttttg catgctttgg
    11881 gatcgaagac ggatttgttt atccgtcacg atcgaccttt aagaagtttt gacaaaacca
    11941 ttgttgatgt cttagttgat gaaatggcag ttaatgggcc gcgtttacac actcatgcag
    12001 aagtggcaaa ggttgtcaaa aatactgatg agtccttgac cctttacctc aaagatggcc
    12061 aagaagttga ggttgaccag ctcatttggg ctatcggtcg caagcctaat ctagaaggtt
    12121 ttagtcttga caaaactgga gtgacgttaa atgataaagg ttatattgag acagatgtct
    12181 atgaaaacac gtctgtcaaa ggtatttatg ccgtgggaga tgttaatggg aaactggctt
    12241 taactccagt tgctgtggca gctggacgtc gcctatcaga gcgtcttttc aatggcaaaa
    12301 cagacgagaa attggactac caaaacgttg ctactgtgat ttttagtcac cctgttattg
    12361 gctctgttgg cttgtcagaa gaagcagcag tcaaacagta tgggcaagaa gcagttaaaa
    12421 catatcaatc acgttttacg tctatgttta ctgctatcac taaccatcgc caaccttgtc
    12481 tgatgaagtt ggtaacagtc ggagataccg aaaaaatagt tggtcttcac ggaatcggat
    12541 acggggttga cgaaatgatt cagggctttg cagtagccat caaaatggga gcaaccaagg
    12601 cggattttga taacaccgtt gctattcacc caactggctc agaagaattt gtcaccatgc
    12661 gctaaaaaat gtagcctaag gcaataaaaa atgatgttaa cagtttttga ggaaagtctt
    12721 ctaaactgct agcatcgttt tttgttaggt gattagggga atatgttttt aaagatattt
    12781 gcgttgctca gacaatattg ccttacctcg gagataaaat aaagtgaccc tgtaacaaca
    12841 aagagttcat cagatgttac ggaaccttgt aaccagtctc tgtaatcttt tacctgtggg
    12901 tatttatcag gataatcctc taaaagattt gcttcaggga aatcaaaagt cgtgacagat
    12961 acttcaaaag tatctagttg agccagcaag tcggctaaag gcttacgttt gagacctgca
    13021 aagagaatat gaataggacg tttgggaaat tcttcttgca gtagagactt taatttagca
    13081 atggaatctg gattgtgagc gccgtctaat agaagattag gttgaataaa ttcggaccgg
    13141 ccaggccaag ttgttgcctc aattcctttt tgaatcgttt ttggagatat tttaggaaag
    13201 gattttctaa gtaattgagc tgtcataatg gctaaacagg cattcgcttt ttgatgttga
    13261 cctaatagtt tgagacggag tttggttaaa ttcaagttat cgtgttgaaa ggaaaacgtc
    13321 ttttctgaag gattgagcaa aaaatctttt cctaattgat ataagcgtga accggctttt
    13381 tgggtaactt gttgaaagac ttgactagcc tcctgctcaa gttgaccgat aataacgggt
    13441 tctttagctt tgataacttc tgctttttgg tgagcaattt ctgctaggct ataacctaaa
    13501 cgttcttggt gatcaaaact aatagaaggg catacgacgg ccagagcatg aaaaacattg
    13561 gttgcgtcgg ttttcccacc aatccctgcc tcaataatgg caatatcaac aggtttaaga
    13621 ttggcaaagt agcaaaacat tatgagcgtc actaactcaa actcggtagg tctatcccaa
    13681 tttgtttcaa gagacatttt agtgagaatg ggtctaatca cgctcacaca ttgcgccaat
    13741 tctaggtctg aaatgggctg gccattaagg caaatccgat cgtgaaaaga gataataaaa
    13801 ggagatgtaa aggttccgac ctgataacca gaagttgaca ggatatgctg taagtaggct
    13861 gtcacagagc ccttgccgtt agttccaaca acgtgaatag cagggaattt gtcttgtggc
    13921 cggcctagtg cctcaagtaa ccaagccatt ctggccaaat cggtcttgcg accattagcc
    13981 ttaaaggtat gaatccagga aatgctatca taggtagtca ttactatttc ttgtccttct
    14041 aacaatgctt ttaagggttc gtaggaagac cagtattagc atcttcagct ccagttgcat
    14101 taggaatttg cgtcccttca gtggctgatg gtgtctcagg agctgtagga gttgtctcgt
    14161 tgtgagaagg tgtggtagaa gatgacggaa gagttgtctt attatcatct gtggtttctg
    14221 aagtacctgt atggttttga ttaccctgag aagactcttt ttcaataatc ttgacaatgg
    14281 tattactcga ttctttgggt gtatcattag aggtcttatc tggtacaggc tgcagtgctc
    14341 ttgaaatggt aatggttgcc acgatgatac tcaaaatact accaataagt gcaatggatt
    14401 tttggaaagc tgtaaaacct gttttaatat gctcggtagg gacacctcct gatttacgag
    14461 gtttttgttg acgggaataa cgtgatgaca tatttttctc ctttaaaatc atcgtaatgc
    14521 caagattaag gaggaggaaa cagaagtcct agctcctctt taacacttca tctatcagta
    14581 taatctagaa aaaaagtgaa gtcaacggtt taccttatgt ctaggacaag gaagtccttt
    14641 gggcttattg taatacgaat attcttgatt tcattttagc tattttgtga tagaataaag
    14701 tattgagtaa aaatgaaggt gacacatgat ttattttgat aatgcagcca caaccatacc
    14761 ttatggagag gctcttaaaa cttaccaaga agtagcaaca aaaatatatg gcaatccctc
    14821 aagtctgcac caattaggga caaatgcgtc tcgcatttta gaagcttccc gtaaacagat
    14881 tgctggtttg ttgggtgtta agtcagaaga aatctttttt acgtctggtg ggactgaaag
    14941 tgctaattgg gctattaagg gaattgcttt tgaaaaaaac gcttttggca aacatattat
    15001 tatctcagcc attgaacacc ctgccgtgag tgaaagtgtc aaatggcttc tcacacaagg
    15061 attcgaagtt tcttatgctc cagtgacaac acagggagtt gttgatgtga atgctttagc
    15121 tgagctgatt agaccagaca ccatcttaat ctcgattatg gctgttaata atgaaatggg
    15181 agctatccaa ccgattagag ccatttcaaa cctattggct aaccaaccaa cgatcacctt
    15241 tcacgttgat gctgttcaag ccattggtaa aataccactc tgtgattata tgactaatcg
    15301 tgtggatttg gcttcttttt cagggcacaa atttcatagt gttcgtggtg ttggcttcct
    15361 ttataaaaaa gcaggcaagc gactcaatcc tctcttgtca ggcggcggcc aagagcagga
    15421 gttacgttca accactgaaa atgttgcagg aattgctagc atggccaaag cattaagaat
    15481 agtcactgaa aaacaagtga gcgtcttacc taaactaaca gcgatgcgag atgtgattta
    15541 caaatctttg tccgcttacc cagatgtgac agtattttca gctcaagaag gctttgcgcc
    15601 caatattttg acctttggga ttagaggggt tcgaggagaa gttattgtcc acgcctttga
    15661 aaaatatgag atttatattt cgaccacaag tgcatgttcg tccaaagcag gtaagccagc
    15721 aggaagccta gtggctatgg ggattcctgt aaaaactgcc cagacagccg ttcgtattag
    15781 tctagacgat gacaacgata tgggacaagt agagcagttt ttgaccatat tcaaacagat
    15841 ttatgataaa acacagaaag ttaggtaaga ttaggtaaga tggactattc agaaattatg
    15901 gttcgccatg gtgaactatc aactaaaggg aagaatcgca tgcgattcat taacaaactt
    15961 aaaaacaata ttcaagacgt actggctcct ttcccagcca ttactgtccg ttcagatcgt
    16021 gataggaccc atgtgtctct aaatggcaca gattatcagc ctattgtaga agctttaaag
    16081 ctggtgtttg gtgttcaagc tctatctcct gtttataaac ttgaaaaaag tgtccctctt
    16141 ttggtaacag ctgttcaaga tatcatgact tctctttatc gtgatggact gacgtttaag
    16201 attgccacta agcgtagtga tcacgcgttt gaattggata gtcgtgagct taacagtctt
    16261 cttggtggag ctgtttttga ggttttacca aatatccaag cccagatgaa acatcccgat
    16321 gtgactctca aagtcgaaat tcgtgatgaa gcagcttaca tttcttatga agagattaag
    16381 ggaacaggcg ggttaccggt aggaacgtca gggaaaggga tgctgatgtt atcgggcggt
    16441 attgattcac cagtagctgg gtatttagcc cttaaacgtg gccttgatat tgaagttgtt
    16501 cattttgcta gccctccgta caccagtcca ggtgccttgg ctaaagccca agaccttact
    16561 cgtcgattaa ctcgttttgg tggaaatatc caatttatcg aggttccttt tacagaaatt
    16621 caagaagaaa ttaaaaataa ggcaccagag gcttacctta tgacattaac ccgccgcttt
    16681 atgatgcgca tcacagatgc cattcgtgag caacgtaagg gtcttgttat tgttaacggt
    16741 gagagcctag gtcaggttgc tagtcaaacc cttgaaagca tgcaggccat taatgcggta
    16801 acatcaactc caattattag accagtcgtg acaatggata aacttgaaat tatcgagatg
    16861 gctcaggcga ttgatacttt tgacatttct attcaaccgt tcgaagattg ctgtactatt
    16921 tttgcaccag accgtcctaa aaccaaccct aaactaggta atgctgaaaa atatgaagaa
    16981 cgctttgata ttgatggtct tgtccagcgt gctgtgtcag gaattgttgt cacagaaatc
    17041 acacctgaaa tcgtcaatga tgaggttgaa aatctcattg atgctttact ttaaaagaaa
    17101 agatcaagtg taaatctttt agtagtcagt aatgatacta ttgaaaagcc tctataaggg
    17161 cttttttgct gcaatgaagg aggaaaattt tgaggcaaga tgttataata gagaaaaagg
    17221 agggtgtgtc ttgattaaaa ctatgcaata caaaaaaacg atggcaacag ttgttgctct
    17281 tatcgtcgca cttttgctat ttggcttgat ttatgattta cttggggttc aaaaaaatga
    17341 gctagcagct caaaaatctg ctcagccaaa ggtcaaaaca gcgcgtgttg tagctaatgg
    17401 cgacatttta attcatgata ttctctacat gagtgctaga aaagctgacg atacctatga
    17461 tttcactcct tattttgaat atgttaagga ctggattagc ggtgctgact tagctattgg
    17521 agattatgaa gggaccatta gcccagatta tcccttagca ggctatccct tattcaatgc
    17581 tccagaagag attgcaggtg ctctgaaaaa tactggctat gatgtagtcg atttagccca
    17641 taatcatatc ttagattccc aattagacgg tgcccttaac actaaaaagg tttttcatca
    17701 attaggtata gacagtattg gcatctatga caaggatcgt tcaaaagaat ccttcttaat
    17761 taaaaatgtc aatggtatca aaattgcaat tttaggttat tcttatggtt ataacggcat
    17821 ggaggccaca cttagccaag aagactatga gaaacacatg tctgatttag atgaagctaa
    17881 gataaaaaaa gaacttcagc tagctgaaaa aaaggctgac gtgaccattg ttatgccaca
    17941 aatgggaaca gaatatgcct tagaaccgac agcagaacaa aaagaacttt accacaaaat
    18001 gattgattgg ggagctgacg tcgtcctagg aggccatccg catgttattg aaccttcaga
    18061 gacagttata aaaggtaggc aaaagaaatt cattatttac tctatgggaa attttatttc
    18121 aaatcagcgg cttgaaaccg tagatgatat ctggactgag cgtggcctat tgatggacct
    18181 tacttttgag aaaaaagata acaaaacaaa aattaaaaca gttgaggccc atccaaccat
    18241 ggttttagcc aaaggtaaag gcattgtggg taaagaaggt tttgaactat acaattatcg
    18301 aacaatggtt ttagaagatt ttatcaaagg tggaaaatac cacgacaaga ttgatgagga
    18361 aaccaaagca aaagtagcac ttgcctatca ggaaattaat gatttagtta acctgaaatg
    18421 gtaacgtttg gtggtttagc atctaacgat aaaaaataga gattaaactt aatttttcct
    18481 tgataaaaag cagttatggt gctaaaatag taacgttgac taaatgcaca tcctgtgcaa
    18541 ccgcgcgaaa atcgttgtca agtagaccaa gtctcacgat tccaggcgag tcttcacaga
    18601 gggaaacctc aaacaaaaat tttataggag gtgcatcatg agcacatacg caatcatcaa
    18661 aactggtgga aaacaagtta aagttgaagt aggtcaagca atctacgttg agaaaattga
    18721 cgctgaagct ggcgcagaag tcacttttaa cgaagttgtt cttgtaggtg gtgacaaaac
    18781 tgtagttggt actccagttg ttgaaggagc tactgtcgtt ggaactgttg aaaaacaagg
    18841 aaaacaaaag aaagttgtaa ctttcaaata caaacctaaa aaaggtagcc accgtaaaca
    18901 aggtcatcgt caaccttaca ctaaagttgt catcaacgca atcaacgctt aatttactag
    18961 cttatgatta aagcaatttt tactcgccaa aaaaatggtc aactgagcag tgttacactg
    19021 acaggtcatg ctggtagtgg taaacatggc tttgatattg tttgtgcctc tgttagtact
    19081 ctagccatta actttgttaa ttctcttgag gtgttagcag attgccaagc attagtagat
    19141 cttaatgatg ttgaaggtgg gtatatggct attacaatac caccacatga caacaaggag
    19201 gaagttcaat tattatttga atcttttctt ctaggaatga ctagtttggc gaaggattct
    19261 tcgaaatttg tcaacactca ggtcatctaa atttaattta agagaggaaa caacattatg
    19321 ttaaaaatga atcttgctaa cttgcaactt ttcgcccaca aaaaaggtgg aggttctaca
    19381 tcaaacggac gtgactcaca agctaaacgc cttggtgcta aagctgctga cggtcaaact
    19441 gtttcaggtg gatcaatcct ttaccgtcaa cgtggaactc atatctaccc aggtgtaaac
    19501 gtaggccgtg gtggagatga cacacttttt gctaaagttg aaggtgttgt acgtttcgaa
    19561 cgtaaaggac gcgataaaaa acaagtttct gtttacccag tagctaaata attgtttaac
    19621 atcgcattat ataaggcttt ccaggtgtct ggaaagccga ttttttattt tgctactcat
    19681 ttgctaccca tattctaaaa gccgatgtag gaagagagct tgtcagcagt tttatctttt
    19741 gaggatttag taacatgagc gtagatattc atggtagttt ggatagtttc acgaccaagt
    19801 gtattggatt ttcttctatc ctactaaaga ttgtagttgc ttatttagag caatagttct
    19861 aattgtaaaa agtcagcata ataaaacaat gtcataagat gttgttataa cgggctttat
    19921 ggtataatta aggatactca ttttaggaag gaaagcaatg aatattcaac aattacgcta
    19981 tgtggtagcc atcgctaata atggaacttt tcgagaagct gcctctaaat tgtttgtcag
    20041 tcagcctagc ttatcagttt ctatcaaaga tttagaggcg gaattagggt ttcaaatttt
    20101 taatcggact acttcaggaa cagtcttgac aagtcaagga ctagtttttt atgagaaagc
    20161 tttagaagta gtcaagtctt ttgattcttt tgaaaaaacc ttttctcaag ctgatctgga
    20221 tcaaaatgaa ttttctattg ctagccaaca ttatgacttt ttgccacctc ttattacagc
    20281 tttttcgcaa caatacgatg gtcatcgtgt ctttcgtatc tttgaatcaa caactattca
    20341 aattttagat gaagttgctc aaggaaacag tgaaattggt attatttact tgaatgtaga
    20401 caatcaaaaa ggtctctttc agcggatgga taagctgggc ttagaatatg tttctctaat
    20461 tccttttact actcatattt atctttcaaa aacgcatcca ttggctaatc gcgaagcgct
    20521 ttatttgaac gatattcaag gattacctgc ggtaaggttt acccaagaaa gggacgagta
    20581 tttgtattat tctgaaaatt ttgtggatac tagtgaatgc cctcgtattt ataatgtgtc
    20641 agatagggca accttgaacg gtattttaga gagaaccaat gcctttgcga caggatcagg
    20701 ttttctcgat catcggagtg ttaatgggat taaagtgata cctctagctg atcatattga
    20761 caatcaaatg atttatgtca aacgaaaaga taaaaacctt tctgttgctg gggccacttt
    20821 tgtgactatt ttaaaagact attttgataa aagaaggaag gccttaacat gaaaaaacga
    20881 ttgtttgtgc ttagcttgat cctccttgta gctttggatc aacttagtaa attttggatt
    20941 gtttctcata tagcgcttgg agaagtgaaa ccctttatcc caggtatcgt cagcttgact
    21001 tacttgcaaa acaatggggc tgccttttcc atattgcagg accagcaatg gttctttgtt
    21061 gtcataacgg ttttagttat cggttatgct atttattacc ttgctactca tccccattta
    21121 aatatctgga aacaattagc tctcttgctt attatttctg gtggaatcgg gaattttatt
    21181 gatcgtttgc gtttagctta cgtgattgat atgattcatt tagactttgt ggattttgcc
    21241 atttttaatg tggcagattc ataccttacc gttggtgtca tattattatt gatatgttta
    21301 tggaaagaag aggattatgg aaattaatgt gataacatcg gggcaacgct tggataaggc
    21361 actagctgat ttaagtcccc tgtcacgtgg tcaagccaat gaccaaatta agcaaggcct
    21421 tgttttagtt aatggtcagc aaaaaaaggc taaatatacg gttcaagcag gagatgtgat
    21481 ttgttttgaa ctccctaaag aagaagtctt agagtaccaa gctcagaata ttcccttgga
    21541 cattatctat gaagatgatg ctctcgccat tattaacaag ccacagggaa tggtagttca
    21601 cccttcggcg ggacaccctt caggaacaat ggttaatgcc ttgatgtatc atatcaagga
    21661 tttgtcctca atcaatggtg tggttcgtcc aggaattgtt catcggattg ataaggacac
    21721 ctccggtctc ttaatggtag ctaaaacaga tgcggctcat caagccttag cagaagaatt
    21781 gaaggctaaa aaatctctca gaaaatacct cgccattgtc catggaaacc taccgaatga
    21841 tcgcgggatg attgaagctc ctataggtcg tagcgaaaag gaccgtaaaa aacaggctgt
    21901 tactgcaaaa ggcaaagaag cagtgacacg ttttacagtg ctagaacgtt ttggcgatta
    21961 cagtctagtg gaattacaac tggaaactgg tcgaacgcac caaattcgtg ttcatatggc
    22021 ctatattggt catcctgttg ctggggaccc tttatatgga ccacgtaaga cactatcagg
    22081 tcatggccaa tttcttcatg caaaaacatt gggattaacg catcctatga caggaaaaga
    22141 aatgatattt actgttgaag ctcccgaaat ttttcaaaag gtgttaaagc tgctaagaaa
    22201 aaaataaaca gcgaggagta gccattattt ttagtcttat atctttgtgt aaagttttta
    22261 acattataaa aaatactaaa aagcatttac gataagccag gaaatatgag aagtctttta
    22321 tgttattggg atatgcaaca tatctgttag agatctttat ttaaactcct taaagaaaag
    22381 agatattcca aatagatgct aggtattgtc ttttttactt gtttttcttt tctttttttg
    22441 ctatactgat tgaaataaaa tattccttta aaacagtcct gtgaggctgt caaggagacg
    22501 gattaaaaac atgcatcatg atacttaatt gtgctatatt ttgctgaatc tccttgtttc
    22561 caaggagatc tttttatttg aatttttaga ggaggtttca acatgaaaac taaggaaatt
    22621 gttgatgacg tgaccatgaa acgcgccatt acccgtatta cttatgaaat tattgaacgt
    22681 aataaacaat tagacaatgt ggttttggca ggcatcaaaa cgagaggtgt ttttctagct
    22741 cgtcgcattc aagaaagact gcatcaatta gaagggttgg atttaccaat tggtgagtta
    22801 gacatcaagc cttttagaga tgacatgaga gttgaggaag acacaactct gatgtcagta
    22861 gatattacag gcaaggatgt gattttgatt gatgatgtgc tttatactgg tcgtaccatc
    22921 cgcgcagcca tcgataactt agtgagttta ggtcgaccag cccgtgttag tctagctgtt
    22981 ttggtggatc gtggccatcg ggaattaccg attcgcgcgg attacgttgg gaaaaatatt
    23041 ccaacaagca gtgtagaaga aattgttgtt gaggttgtcg aagtcgatgg ccgtgatcgt
    23101 gttagcatta ttgacccaac ataagaaaga ggttttactg tgaaagatgt catttatgat
    23161 gtggaagaag tgccaaaggc aggtatgtta gttggtttgt cctttcagca cttatttgct
    23221 atgtttggtg cgactgttct ggttcccatt ctagttggaa ttgacccatc agttgctttg
    23281 ttatctagtg gtttaggaac ccttgcccac ttatcagtga ccaaatttaa aattccagcc
    23341 tacatgggct caagttttgc ttatatagca gctatgcagt tactgatgaa gacaaatggt
    23401 attggtgctg tagctcaagg ggctatgaca ggaggtctcg tttacctgat tgtagctttg
    23461 attgttaaag ctattggcaa tgattggatt gataacatct taccaccgat tgtggttggt
    23521 ccgattgtta tggtcattgg tctaagccta gcttctacag ctgttaatga tgtcatgcta
    23581 aaaaatggga actataatct gacttatctt gttattgggt tagtcacctt attatcagtt
    23641 atttttttca atatttatgg taagggaatt gttgctattg taccgctttt attagggcta
    23701 ttagttggtt atgttgtagc ccttttagtg ggtgttctca ccggtcaaga aattgttgat
    23761 tttaccaatg tggctcaggc caaatggttt agtatcccat cagtggaaat tcctttctta
    23821 acctacgggg ttaaattcta cccaagtgcc attttaacta tggcacccat tgcctttgtt
    23881 acaatgacag aacattttgg acacattatg gtcttaaata gtttgacaaa aagagattat
    23941 ttcaaggatc caggacttga aaagacttta actggtgatg gttttgcgca aatcattgcc
    24001 ggcttcttag gggcacctcc ggtcacttct tatggtgaaa acatcggtgt aatggctttg
    24061 aataaaatat tctcggtcta tgttattgca ggtgccgcag tgattgccgc tctcctcagt
    24121 tttatcggta aggtatcagc cttaattcaa tctattccaa caccagttat tggaggtata
    24181 tcagttgcct tgtttggtgt gatagcttct agcggtttga aaatcttgat tgaatccaaa
    24241 gttgatatgg ataataagaa aaacttattg attgctagtg ttattttggt ctctgggatt
    24301 ggaggattga tgcttcaagt aaatggtctt caaatttcag gtgtcgcttt ctcaacactc
    24361 cttggcatca tcttatatca ggtacttcct gaaaaatagg aagaattgtt gttagaccac
    24421 ttacatagtc atcagtcgtt agtgataaag gggataatca tgtcagttgt aaataatcgc
    24481 gttgcactta ccaatttagt ttcaatggaa gcattaacca ccgaagaagt tttaggtctt
    24541 atcaaccgtg gttcagaata taaggctggt aaagttgtta tttcggatca tcaaaaggat
    24601 cttgttgcca atttattctt tgaaaactcc acccgaaccc ataagtcttt tgaagtggct
    24661 gagaagaaac tcggcttgac agttcttgat ttcaatgctg atgcaagtgc ggttaacaag
    24721 ggagaaagtt tgtatgatac tgtgttaacc atgagtgcac ttggaacaga catctgtgtg
    24781 attcgtcacc cagaagatga ttattacaag gaattagtag aaagtccaac tattacagct
    24841 tccattgtca atggaggaga tggttctgga caacacccga gtcaatgttt acttgactta
    24901 ttaaccatct atgaagaatt tggacgcttt gaaggcttaa agattgcgat cgctggtgac
    24961 ttaactcact ctagggtggc aaagtccaac atgcaaatcc tcaaaagatt aggagcagag
    25021 ctttatttct atggacctga agaatggtat tcagaagcct ttaatgctta cggcacttat
    25081 attgctattg accagattat taaggaattg gatgttctta tgttgctgcg tgtacagcac
    25141 gaacgtcatg acggccatca gagtttttca aaagaaggtt accatcaagc gtttggattg
    25201 acacaggaac gttaccaaca attaaaagat tctgctatta ttatgcatcc agctccagtt
    25261 aatcgggatg tggaaattgc agatagtttg gtggaagctc ctaaagcgag aattgtatct
    25321 cagatggcta atggtgtctt tgttcgcatg gctattattg aagccatttt gaatggtaga
    25381 aataaaaact catgatgaaa gattaaagca tgtttagaag gtaggaaaag gtaggaaaat
    25441 gacaaaacga ttacttattt tagaagacgg cactattttt gaaggagaac cctttggtgc
    25501 tgatattgat gtgactggtg aaattgtctt taatacagga atgacaggct accaagaatc
    25561 catcactgac caatcctaca atgggcaaat tttaaccttt acctatcctt tgattggaaa
    25621 ttatgggatt aatcgagatg actatgagtc catttcaccc acctgtaaag gggttgttgt
    25681 gtctgaagtc agtcggttgg caagtaattg gcgcaagcaa atgacgctag atgcgttctt
    25741 gaaaataaaa gggattccag ggatttcggg aattgatacg agagctttga ccaaaattat
    25801 tcggcaacac ggtaccatga aagctacgat ggcagatgat ggagatagta tccagcattt
    25861 aaaagatcaa ctgcgtgcaa cagtcttacc gactaacacc attgaacaag tgtcaactaa
    25921 aacagcttat cctgcaccag ggatcgggaa aaatattgta ttggttgatt ttggtttaaa
    25981 acattctatt ttaagagaat tttctaaaag acaatgtaat atcaccgttg tccctttcaa
    26041 catcactgca gaagaagtgc tccaactaaa tccggatggc ttgatgctat ctaatggccc
    26101 aggaaaccca gaagatttgc cagaggcttt agacatgatt cgtggggtac aaggtaagat
    26161 tcctattttt ggtatttgta tgggacatca actctttagt ctagcaaatg gtgctaagac
    26221 ttgtaaaatg acctttggtc atcgtggctt taaccatgcc gttagagaaa ttgcaacggg
    26281 aagaattgat tttaccagtc aaaaccatgg ttatgccgtt gaacgtagta gtctacctga
    26341 tactttaatg gttacgcatg aagacattaa cgataagacg gtcgaaggag tgaaacatag
    26401 agattttcca gctttttcag tccaatttca ccctgatgcg gctccaggac ctcatgatgc
    26461 cagctactta tttgacgaat ttttggaaat gattgattct tggagatgta cgagtaaata
    26521 gtaaatcagt tgcaatttca cgactatatc acctcttgtt actctattta ttaacattta
    26581 cagtaatatt atttaatgtt gctctgtgag gcaacaaata gagaaaggaa ggcaaggaga
    26641 acacaagtaa ataatttagt aaaaagttag gttttcaaag agataaagct cttattgaga
    26701 agtgctgact ttaccgcttc ttgtggtatt cttggtatca ttaattatgc caaaacgaaa
    26761 agatattcaa aaaatcatgg ttatcgggtc tggcccgatt attattggac aagctgctga
    26821 atttgattat gcagggactc aggcctgttt ggctctaaaa gaagaaggct acaaagtcat
    26881 acttgttaat tcaaatcctg caacgattat gacagataaa gaaatcgctg ataaggtata
    26941 tattgagcct ttgactcttg aatttgttaa tcgtatcatt cgaaaagaaa ggccagatgc
    27001 catactgcca accttaggtg gccaaacggg cctcaatatg gcaatggcgt tatctaaagc
    27061 tggtattctt gatgatttag agattgaatt gttaggtact aagttatctg cgattgatca
    27121 ggcagaagac agagaccttt tcaaacaatt aatgcaagaa ctagaccaac ccattccaga
    27181 atctacaatt gttaaaacag ttgatgaagc tgttacattt gctagagata tcggttatcc
    27241 agtcattgtg cgcccagctt ttactcttgg tggaactggt ggaggaatat gtagtagtga
    27301 agaagaactt tgtgaaatta ctgaaaacgg cctaaagtta tcaccagtca cacagtgttt
    27361 gattgaacgc tcaattgctg gcttcaaaga aattgaatac gaagtaatgc gagatagtgc
    27421 tgataacgcg ctggttgttt gtaatatgga aaactttgat cccgtaggga ttcacacagg
    27481 agattctatt gtatttgcac caacacagac cctttctgat attgaaaatc aaatgttacg
    27541 tgatgctagt ttaaaaataa ttcgagctct gaaaattgaa ggtggctgta acgtccagtt
    27601 agcactagat ccttatagtt tcaaatatta tgttattgaa gtaaatccta gagtgtctcg
    27661 ttcctctgcc cttgcttcaa aagcaacagg ttatcccatt gccaaattgg ctgcaaagat
    27721 tgctgttggc ctaacacttg atgaaatgat taaccctatc acaggcacta cttacgctat
    27781 gtttgaacct gcccttgatt acgttgttgc taaaattccg cgttttccgt ttgataaatt
    27841 tgaacatggt gaacgccaac tgggaactca aatgaaagca acaggtgaag tcatggctat
    27901 tggccgtaat ttggaagagt ccttactaaa agcctgtcgt tctttagaaa ttggtgtttg
    27961 ccataatgag atgacaagtt taagtaacat tagtgatgaa gagttagtga ctaaagtgat
    28021 taaagctcaa gatgatcgac ttttttactt gtcagaagca atacgacgag gttatagtat
    28081 cgaagaactt gagagcttga ccaagattga tttatttttc ttggataaat tacttcatat
    28141 tgttgaaata gagcaagaat tacaaatgca tgttgaccat ttggaaagcc tcaaaaaagc
    28201 aaagcgttat ggattttcag atcaaaaaat tgcagaaatt tggcaaaagg atgaaagtga
    28261 tatcagagcg atgagacatt ctcatagcct gtatcctgtc tataaaatgg tagatacttg
    28321 tgcagctgaa tttgatgcta aaacccctta tttttattca acatatgagt tggaaaatga
    28381 atctgttcag tcgaataaag aatcaatttt agttttaggt tcaggcccta ttcgtattgg
    28441 tcaaggggtt gaatttgact acgcaacggt tcattctgtt aaagccatcc aaaaagctgg
    28501 ctatgaagcc attatcatga attcaaatcc ggagactgta tctacagatt tttcggtatc
    28561 agataaatta tattttgaac cgttaacctt tgaagacgtc atgaatgtga tagatttaga
    28621 gcagcctaag ggagtaatag ttcagtttgg aggacaaact gctattaact tagcacaagc
    28681 actttctgag gcgggtgtta caatattagg aacacaagta gaggatttgg atagggctga
    28741 agacagagat ttatttgaaa aggcgttgaa agagcttgga atcccacaac cacaaggtca
    28801 aacggcaact aatgaagaag aagctttaga ggcagctaaa aaaattggtt ttccagtctt
    28861 agttagacct tcttacgtac ttggtggccg ggctatggaa attgttgaaa acaaagaaga
    28921 tcttagagaa tatataagaa cagcggttaa agcaagtcct gaacatccta tcttagtgga
    28981 ctcttatatt ttcggtaagg agtgtgaagt ggatgccatt tcagatggaa aatcagtctt
    29041 aattcctggt attatggagc acatcgaaag agcaggtgtt cattcaggag attcaatggc
    29101 agtttatccg ccacagcaat tatctaagca aattcaagaa acaatagctg agtatactaa
    29161 acgtttagcc attgggttaa attgtattgg tatgatgaat gttcaatttg ttattaaaaa
    29221 tgaacaagtt tatgttattg aagtgaatcc acgcgctagt cgtaccgtac ctttcttatc
    29281 aaaagtaaca ggtattccga tggctcagat tgctactaag ttgattttag gtcaaacatt
    29341 aaaggatcta ggatatgaag atggtcttta tccccaaagt ccactggtgc atatcaaagc
    29401 gcctgtgttt tcatttacaa agttggcaca ggttgatagt cttttaggtc ctgaaatgaa
    29461 atcaactgga gaagtaatgg gttcggatac tagtcttgaa aaagcacttt ataaagcgtt
    29521 tgaagccaat aattctcatt tatcagaatt tggtcaaatt gtctttacta tagcagatga
    29581 tagtaaggca gaagctctaa gtctagcaag acgatttaag gcgattggct atcaaattat
    29641 ggctactcaa ggtacagcag cttactttgc tgagcaaggc ttaagcgcgt gtttagttgg
    29701 aaaaattggt gatgctgcca atgacatccc gacactcgtg cgacatggtc acgttcaggc
    29761 aattgttaat acagttggaa ttaaacgcac agctgataaa gacggacaga tgattagaag
    29821 ttcagctatt gaacaaggag ttcctttatt tacagcttta gataccgcaa aagctatgtt
    29881 aacggtttta gaaagcagat gctttaacat cgaagcgata taaaaattaa aaaaatcatt
    29941 tttaagaaaa cttaaaaatg atttttttag attataatga caaaagtttc agtaagctat
    30001 taatttgtca tagcatataa gtcattatct tgtggcttgt tttcgactaa gggctaagaa
    30061 tttcttgaca acaatataaa aaggtcatat acttgtctta tacaaatagt acaaaagagg
    30121 aggatagaaa tgtctaaaag aggaaaaatt aaaataacaa cgaaaacaaa gcttattaca
    30181 gctagtgtta taacgctagt attaattata actggaatag tcttgtggaa acaacaacga
    30241 aatacgctaa cagctgatat cgctaaagaa ccttactcta ctgttagtgt aactgaaggg
    30301 agtattgctt cttcgacttt actatcaggt actgtaaagg ctttatcaga ggaatatatt
    30361 tattttgatg ctaataaagg aaatgatgca actgttacag ttaaagtagg tgatcaggta
    30421 acgcagggcc agcaattagt tcaatataat acaacaacag ctcagtcagc ttatgatact
    30481 gctgttagga gtcttaacaa gattggccga caaattaatc atcttaaaac atacggagtt
    30541 cctgctgtta gtacagaaac taatagagat gaagctaccg gtgaagagac gacaacaaca
    30601 gttcaaccat cagctcagca aaatgctaat tataaacagc agctgcaaga tttaaatgat
    30661 gcttatgcag atgcacaagc agaagtaaat aaagcgcaga tagcgttaaa tgatacagta
    30721 gttatcagta gtgtctctgg aactgttgtg gaagtaaata atgatattga tccttcttca
    30781 aagaacagtc aaacacttgt tcacgtagca accgaaggac agcttcaggt gaaaggaaca
    30841 ttgacagagt atgatttagc aaacgttaag gttggtcaat ctgtaaaaat taagtctaaa
    30901 gtttattcta atcaagaatg gactggaaaa atatcatatg tttcaaacta tccaactgag
    30961 tctaatgcag gttcaacaac gccagcaggt agcactggag cgggaagttc tacaggagct
    31021 acctatgatt acaagattga tattataagt cctctcaacc agcttaaaca aggcttcact
    31081 gtttctgttg aggttgttaa tgaagcaaaa caggccttag ttcctttaac ggctgttatt
    31141 aagaaagata aaaaacacta tgtttggact tatgatgatg ctactggcaa agccaaaaaa
    31201 gtagaggtga cacttggaaa cgcagatgca caacaacaag aaattcataa aggagtagct
    31261 gttggtgaca ttgttattgc caatccagat aaaaatatca aaccggataa aaaactagaa
    31321 ggggttattt caataggtac caacacaaaa ccggaaaaag attctcaatc aaagaataaa
    31381 aaatcagggg tggataaata gtgtcgcatg aaaaaaaaca attaatgcaa ttatcaaata
    31441 ttgtgaagag ctatcaaaat ggggatcaag ttcttaaagt tttgaaaggt attaatttaa
    31501 cagtatatga gggtgaattt ttagctatta tgggtccgtc tggttcggga aaatcaacac
    31561 taatgaatat tattggttta ttagatcgtc caacatccgg agattacaca ttacataata
    31621 ctaaaataga aatccttaat gatcgtgaat tagcaaaagt acgaaatgat gaaatcggct
    31681 ttgtctttca acaattcttt ctgttagcta aattaactgc attacaaaat gttgaattgc
    31741 ctcttattta tgctggtgta aacgtctcaa aaagacgtga acaggctaag caatttcttg
    31801 aaaaagtagg acttggacga cgtatcaaac atctaccgtc agaactgtca ggaggtcaaa
    31861 agcaaagggt ggctatcgca cgagctttag taaatgaccc atctattatt ttagcggatg
    31921 aaccaacagg tgcactagat actaaaacag gtcagcaaat tatggaactc ttgacagagt
    31981 taaacaaaga aggtaaaaca attattatgg ttactcatga accagaaatt gctgattttg
    32041 caactcggaa aattattatt cgtgatggtg atatcacaac ggatactaca gctagtgttg
    32101 ttattgacta ggaggaaaaa taatggaaaa ttggaaattc gctcttagct caatttgggg
    32161 gcataagatg cgctcaatcc tgacaatgtt gggaattatc atcggtgtag cagcagttgt
    32221 gattattatg gggttgggaa atgctatgaa aaatagtgta acaagcacat tttctagcaa
    32281 gcaaaaagat attcaactct attttcaaga aaaaggagaa gaagaagacc tgtatgccgg
    32341 attgcacacg catgaaaata atcacgaagt gaagccagag tggttagaac aaattgttaa
    32401 agatatcgat ggtattgatt cttattactt taccaattct gctacttcta ctatttcgta
    32461 tgaaaaaaag aaagtagaca atgcttcgat cataggggta agtaaagatt attttaatat
    32521 aaaaaactat gatatcgtag ctggtcgtac actaacagat aatgattatt ctaatttttc
    32581 gcgtatcatt cttttagata cagtattagc cgatgaccta tttggcaaag gtaattataa
    32641 gtcagcttta aataaagtgg taagtttatc tgataaagat tatttagtta ttggtgttta
    32701 taaaactgat cagacgccag tttcttttga tggattatca ggcggcgctg tcatggcgaa
    32761 tactcaggta gcttcagagt ttggcaccaa agaaatagga tctatctaca ttcatgtgaa
    32821 cgatattcaa aacagtatga acttaggaaa tcaagcagct gatatgctaa ccaacatatc
    32881 gcatattaaa gatggacagt acgctgtccc tgataatagc aaaatcgttg aagaaatcaa
    32941 tagtcagttc agtatcatga caacagtcat aggttcaatt gcagcgatct ctcttttagt
    33001 gggaggaatt ggtgttatga atattatgtt ggtatctgtc acagagcgaa ctagagaaat
    33061 tggtttacgt aaagcacttg gtgcaacacg cctgaaaatt ttatcacaat ttttgattga
    33121 atccgttgtt ctaacagttc ttggaggctt gataggatta ttattagctc aattaagtgt
    33181 aggggcttta ggaaatgcga tgacattaaa aggagcttgt atttctcttg atgtggcctt
    33241 aatagcagtt ttattttctg cctcaatagg tgtctttttt ggaatgttgc cagctaataa
    33301 agctagtaag ttagatccaa ttgaggcatt acgttatgaa tagaatagtt cgtatcaatt
    33361 aatctataga cgctgactag tttaacgtct gattatacct agtttttgta ttagcacagt
    33421 agttatatca ttgaagtgtt agtgcatttt ttgaggtgat aatatctagc aaagctatca
    33481 ttggtatgat gatgtggata gcgtataagt gatacatctc ttatttctag ctgaacttcg
    33541 gttcggctag gaagttgtca ggcaatgagt tgtttaaaat aaaggagatt agttcaatga
    33601 catttttatc tgatttgata tcattaatga caaaaatcag attatcttgg gtaataaagg
    33661 cgggtatttt tcaattatta tttgtaac
//
LOCUS       DAUGJR010000018        32836 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUGJR010000018 DAUGJR010000000
VERSION     DAUGJR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32836
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.018"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            134..295
                     /gene="sagA"
                     /locus_tag="VH800_000871"
     CDS             134..295
                     /gene="sagA"
                     /locus_tag="VH800_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEQ8361950.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            517..1467
                     /gene="sagB"
                     /locus_tag="VH800_000872"
     CDS             517..1467
                     /gene="sagB"
                     /locus_tag="VH800_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEQ8361951.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1464..2522
                     /locus_tag="VH800_000873"
     CDS             1464..2522
                     /locus_tag="VH800_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEQ8361952.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNDPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSDALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQVLPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2542..3900
                     /locus_tag="VH800_000874"
     CDS             2542..3900
                     /locus_tag="VH800_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEQ8361953.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3875..4546
                     /locus_tag="VH800_000875"
     CDS             3875..4546
                     /locus_tag="VH800_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8361954.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4543..5226
                     /locus_tag="VH800_000876"
     CDS             4543..5226
                     /locus_tag="VH800_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEQ8361955.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLVALSYQDFLDV
                     LLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGTVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5249..6172
                     /locus_tag="VH800_000877"
     CDS             5249..6172
                     /locus_tag="VH800_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361956.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6181..7308
                     /locus_tag="VH800_000878"
     CDS             6181..7308
                     /locus_tag="VH800_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361957.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLETKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSFLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            7305..8423
                     /locus_tag="VH800_000879"
     CDS             7305..8423
                     /locus_tag="VH800_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361958.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALISFSSLLLKPTKL"
     gene            8994..11726
                     /locus_tag="VH800_000880"
     CDS             8994..11726
                     /locus_tag="VH800_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEQ8361959.1"
                     /translation="MINKKCIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERPYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGCVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      11891..12006
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            12004..12504
                     /locus_tag="VH800_000881"
     CDS             12004..12504
                     /locus_tag="VH800_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEQ8361960.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12698..14656
                     /gene="ligA"
                     /locus_tag="VH800_000882"
     CDS             12698..14656
                     /gene="ligA"
                     /locus_tag="VH800_000882"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEQ8361961.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPYQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            14670..15692
                     /locus_tag="VH800_000883"
     CDS             14670..15692
                     /locus_tag="VH800_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8361962.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     GQELEE"
     gene            16085..16282
                     /locus_tag="VH800_000884"
     CDS             16085..16282
                     /locus_tag="VH800_000884"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEQ8361963.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16317..17033
                     /gene="atpB"
                     /locus_tag="VH800_000885"
     CDS             16317..17033
                     /gene="atpB"
                     /locus_tag="VH800_000885"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEQ8361964.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17051..17545
                     /gene="atpF"
                     /locus_tag="VH800_000886"
     CDS             17051..17545
                     /gene="atpF"
                     /locus_tag="VH800_000886"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEQ8361965.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRLQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17545..18081
                     /locus_tag="VH800_000887"
     CDS             17545..18081
                     /locus_tag="VH800_000887"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEQ8361966.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSQAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18097..19605
                     /locus_tag="VH800_000888"
     CDS             18097..19605
                     /locus_tag="VH800_000888"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEQ8361967.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19621..20496
                     /locus_tag="VH800_000889"
     CDS             19621..20496
                     /locus_tag="VH800_000889"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEQ8361968.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20658..22064
                     /gene="atpD"
                     /locus_tag="VH800_000890"
     CDS             20658..22064
                     /gene="atpD"
                     /locus_tag="VH800_000890"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEQ8361969.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVADTVRGFKEILEGKYDELPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22077..22493
                     /locus_tag="VH800_000891"
     CDS             22077..22493
                     /locus_tag="VH800_000891"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEQ8361970.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22759..23016
                     /locus_tag="VH800_000892"
     CDS             22759..23016
                     /locus_tag="VH800_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEQ8361971.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23081..24352
                     /gene="murA"
                     /locus_tag="VH800_000893"
     CDS             23081..24352
                     /gene="murA"
                     /locus_tag="VH800_000893"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8361972.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24356..24544
                     /locus_tag="VH800_000894"
     CDS             24356..24544
                     /locus_tag="VH800_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8361973.1"
                     /translation="MTNGLKYVLEQMLLLFIIAALACLFLAIGLMIGYSFMGDGQSPW
                     HILSMDKWAELVNKFTGK"
     gene            24580..25119
                     /locus_tag="VH800_000895"
     CDS             24580..25119
                     /locus_tag="VH800_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEQ8361974.1"
                     /translation="MLTRKKRKRVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFK
                     PAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKP
                     YLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVP
                     NVQAGLTVDYRTGQIAINL"
     gene            25402..26445
                     /gene="pheS"
                     /locus_tag="VH800_000896"
     CDS             25402..26445
                     /gene="pheS"
                     /locus_tag="VH800_000896"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8361975.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGDERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            26655..29060
                     /locus_tag="VH800_000897"
     CDS             26655..29060
                     /locus_tag="VH800_000897"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEQ8361976.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPADGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGNLDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTSIKLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            29170..29547
                     /locus_tag="VH800_000898"
     CDS             29170..29547
                     /locus_tag="VH800_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEQ8361977.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            29540..29926
                     /locus_tag="VH800_000899"
     CDS             29540..29926
                     /locus_tag="VH800_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEQ8361978.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            29999..31075
                     /locus_tag="VH800_000900"
     CDS             29999..31075
                     /locus_tag="VH800_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8361979.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GISNKTITTAVLMQTFFLSFLGSGLGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMI
                     CFALLGTLFSVFNIIRIDPLKAIG"
     gene            31085..31753
                     /locus_tag="VH800_000901"
     CDS             31085..31753
                     /locus_tag="VH800_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361980.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYRMQDGEL
                     CQER"
     gene            complement(31855..32772)
                     /locus_tag="VH800_000902"
     CDS             complement(31855..32772)
                     /locus_tag="VH800_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEQ8361981.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQSDYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRTVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
BASE COUNT        10089 a         5585 c         6850 g        10312 t
ORIGIN      
        1 gatagttgtt gtgttacaac agtacaattg agctagcctt gtccttgttg tgttaacttt
       61 atttttaaaa taaggttaaa aataaacgac tcgcgttctt atcagttact tattagataa
      121 ggaggtaaac cttatgttaa aatttacttc aaatatttta gctactagtg tagctgaaac
      181 aactcaagtt gctcctggag gctgctgttg ctgctgtact acttgttgct tctcgattgc
      241 tactggaagt ggtaattctc aaggtggtag cggaagttat acgccaggta aataatctat
      301 ttagcatctc tatgtgatag tgatattaag gtaatgagtt tgctagcaac taagttatct
      361 ttggtaactt ctgattatag atgaatggca tagaggtgtt agaaaacatg agacaaaagt
      421 aatcttcttg atgctaacgt ctcaggtaat tagcaggtac tagatagtac ctgctaatta
      481 ctatatgttt agtaaaatga gataggaaag atagttatgt cattttttac aaaggaacaa
      541 caacctaaag agaattgtcc gccaataact gttgaaaaag caaggcaatt gtttgaattt
      601 aatacaaacc acttgtcctt atcggattac catcatcaaa cggtgctaaa aacgtcaaag
      661 cagctagttg ctcaacattt aatgcctaat gcaaccgata atcttagtca acattttttg
      721 atgaactata aagctaataa taattattta ggcttccaag ctagtattgt cgactttttt
      781 acagattctg ccgttgctaa tttttcaagt agttacgttt atgaaagtca ggaaaagata
      841 attcgtttac caaaacctac caagatatca actgctctgt cgacatgtat tataaaacga
      901 agaagtcatc gtcaattttc agatagacaa atgcctcttc aagatttatc aaacattctt
      961 tattatgcat gtggtgttag ttcacaagca tcaattagag atggagcatc agataagatt
     1021 acactcagaa actgtgcttc aggtggaggt ttatacccta ttcatttagt tttttatgct
     1081 agaaacatca gtaaattaat agatggtttc tatgaatatc taccctatca gcatgcacta
     1141 aggtgttatc ggcatagctc tgaggaaaac gttagagatt ttgcggaata cggtgctatt
     1201 aatgctgaaa attgtaatat tattattatt tatgtctacc attacatgaa aaatacacgt
     1261 aaatatggga atcaggcgac tgcctatgct tttattgaat caggagaaat agcccagaat
     1321 attcaattga ctgcaactgc cttaacttat ggaagtattg atattggtgg ttataataag
     1381 gaatatctcc aagaattatt agatttagat gggctaggag agcatgtgat tcacatgaca
     1441 ctcgtaggaa ctaaggagtc tcaatgaaat atcaacttaa tagtaatgtt cgtgtcgtga
     1501 catttcaaga tacattttgt tttagaaaag gaatctggga ctttaatgaa gccattctag
     1561 atttgacaca agaacctcaa aatttaaaga tagtttatca agaaatagtt tcacagttgg
     1621 ttaagggagt agccattgat actgaaactt atgaaaatac tttagaacct gagacgttcg
     1681 ctaatttaat ggaagtcatt tcaggcttgt attacaatga tatgctgatg cttgaggatg
     1741 actacaatct tgaagaaaat gtcatgaaaa ttttaatggg taatttccgt tttatggcgc
     1801 aagcaggtca tatggtaagc aatgatcctg ttttgtttat cagtgattcg acttatgtta
     1861 atgaatctgc tgagttgcta gctgaacaac tgcatttaca attgcaagtg gctagtgatg
     1921 acttaaaaat gttaattcag cagacagatg ttagttcgcg tttagatgct ttggagcatc
     1981 gccgtaacat gaattgttta tcagatgcct tgtgcgatta ccaaagtatt attatttgtc
     2041 aagaacgctt gaatattatg atgttgcgac acttgaatga agttagcgta gctatgaaaa
     2101 aacaattagt gattggtttt gtagatggac cattcttgca cacttgtact ttgaatcctc
     2161 cccatagtgc tgactttgat agcttagaaa gaagagtttt ggcacgttta caagactcaa
     2221 ctctctatca acattttgct aatcaggttt taccagccac acaagatgtg agccaggcct
     2281 atttaccatt gttaaatgtt ttaatgaatt tagtcgttag cgaagctttc attattgctc
     2341 aaacaggtag ttctaaattt gagggacgtt tattaagcat ttacttaccg acgcttgaga
     2401 ttcaggtcca agatattttg aaaatgtcta attcacagac acaaggagct ttggcaaaat
     2461 taaagtatga ggatcagcag atatcaacac gtgagattgt taaaaaactc cttgacgagt
     2521 aacctataag gagaatctat tatgttatac tattatcctt cttttaatca tatttttgat
     2581 gaattaaaaa gtttaagtgg caatcgaaca ggtatcttaa atcaatctca agttccagtt
     2641 tgcaaccatc ctcacgatgt ttacttaaaa agtattactg gccaaatgcc agattatcat
     2701 aaacaattta taggtgagtt gagtcaagtt agttatcaca ttattggtta cggcagttac
     2761 tatgaagaag cacttatcaa gtatttagga gaaagtattg aacgctatgc tactgtaatt
     2821 gccggagact tactatcaga tcggattgtc tatgcttctt ataatgagtt aaaactgtta
     2881 cataaagtga tgcctttaga atacttgcaa gtgtttaccc aagaacagat cgcattatct
     2941 tgtgacttgc aaatgatgat gtgcgataaa atggtaactg agaacgatgt attgggctgg
     3001 gttaaatgtc ccatgttctt tgaggacgca gagatgtatg ttccagctca aatgctttgt
     3061 gttgggtata aaacaaatga gactgtagga gaaagacgga taataccagg attttctacg
     3121 ggaacagctt ctcacaaaac gttagaagcg gctatgtgca acagtttgat tgaatacatc
     3181 cagatcgatt caatgatgct tagctggtat actaagaagc cttgccccaa gattattgtt
     3241 gatgatcctg atattgaagt gattttagaa gaagctagac tgggaaaaga cagtctatac
     3301 gacattattc ctattgatat gactgtagga gaagataatc ctctttatac gtttggaatc
     3361 attctcaaaa ataaatatga tgaagggcct tacctcttgt ttggagtgca ggctgggtta
     3421 gatcctaaac atgctttgct aagagggatc atggaagctt cagctattag ctatagttac
     3481 tactataatc ttttatatca aaaagcttcc cttgcaaata ttgaatgcga agaacctttg
     3541 tttttagatt tagatagtaa tgtcttctat tatgcacatc ccaaggacca agaccataaa
     3601 tggaaggcct ttgaaccttt gatttcagga gaagttctgt taagtgattt ggaagatcat
     3661 tctggtaaag ataaaaaaga agatttgaag actttattag cttatgctaa gaaagtcagt
     3721 cctaatgctg tctttttaga tattacacct cctgaagctc tagaaaaagg ctggtacgtc
     3781 acgcgagttc tgatgccaga acttcttgaa atgtgtatac cagcatttcc ttttgctaat
     3841 catccacgaa tgagacagtt tggaggtgta acaaatgcct ttgtccatcc aatgccttaa
     3901 tctttgtttt ttgttggtaa ctttttgtcc ttcaattcct atgcaagcta tttttggaaa
     3961 ggaagatagt ggttatgcat ttaatttaat tggttttcta agagcaactc tgatttatga
     4021 cattttggct ttggtaagta tttatgtttt gtcacctcaa ataaccttgt ctcttgaaag
     4081 tattgatagt aagacgttct ttatgggact tgtattttgc gtcttgatag tactgattga
     4141 actcgttttc ttacatggtt tacgttgttg gcaaaaaaag caatggcttc ctgcaacttt
     4201 ctcgtttgta ggaacgacaa atgattggtc taagattggc tatcctttat tactagcttt
     4261 atttgaagag acgatttatc gttttttgtg gtttaatata ttagcttttc aatggcattt
     4321 accaacaatt attgttttaa ttgtaactag tttttgctat gctttaaatc acttattgat
     4381 ggggaaatcc attttttatg ctaagttggt aacaggcatc atttatggta gtatttacat
     4441 gctgactagt caattgtggt tggttgtgat aatgcatgta ggaggtaact tgctagttga
     4501 gtgtcttagc catcttcaaa caaaaaagaa gaaggaggtg acatgatgct attggttttg
     4561 ctgtcgtttt taggtctaac tactctttgg ttgaccagtt atcgaagacg ttgtttggct
     4621 agatggcatc ttcaatggtt agtggcctta tcctatcaag attttttaga tgtcttactg
     4681 agtctgtttc aatttgtcgt tattatactt gttttattct tttactcagc tactattaat
     4741 ctaggagagg ttctgacctt tttgacacaa actagctggc attggcagat tctttgttat
     4801 ttagtgttat atcttatggc catcatagag atgacgcttt tagttttaat tcttatcttt
     4861 gatgttttgc tccagaaaga cagtcgattg ctctttaaaa aaataacttg gctgcctttt
     4921 agacaagata aaccagtctt aagtatactt ttactaggca cagttattct agtagacagt
     4981 ctcttttatt tgggcttgct tatattatta ggagaacagt cgctaacaag tttagcaacg
     5041 cttattttag gttatgggat agtcaaggct tgtcgctatt caggttggtt aaatgtacta
     5101 ttagcttttt gtcttttcac tatagttgga ctatgggcag ttacggcaac tttattatat
     5161 ggttggctag taggtgcgat gatattaacg gtgacttatt tgatgattag ttgcaaagag
     5221 tattagcaat attaaaaagg agtgatatat gagttttgta caattaacaa atgttgtcaa
     5281 gtcctacaaa aacggcaaga aagctgtcaa tgatgtttcc ttgtctattg aagcaggtaa
     5341 tatttatggt ttgttaggac caaatggtgc tggtaagtct accttgatta atcttatctt
     5401 aggcttgatc cctttgagtt ccggtaaaat tactgtttta gggcaatccc aaaagactat
     5461 tcgaaaaata agttcgcaga taggttatgt tcctcaagac attgctgttt atccagacct
     5521 aactgcttat gaaaatgtag aactatttgg gtcactttat ggcttaaagg gagctcagct
     5581 taaaaaacaa gttctaaaaa gtttagaatt tgtggggcta cactcccaag ctaagcagtt
     5641 tccaagtcaa ttctcaggag gaatgaagag acggttaaat atcgcttgtg cgctagttca
     5701 ttcacctaaa ttaatcattt ttgacgaacc gactgtaggg attgatcctc aatcacgtaa
     5761 tcatatttta gagtcgattc gtttgctaaa caaagaaggt gctacagtta tttatacgac
     5821 ccattatatg gaagaagtag aggctctttg tgattatatt tttattatgg atcatggtca
     5881 agttattgaa gaaggaccta aatttgaact ggaaaaacgt tacgttgcaa atctagcaaa
     5941 ccagattatt gtaactctaa cagattcacg tcatttggaa ctggcagata agcctgattg
     6001 gtctttgata gaagatggag aaaaactcat gttgaagatt gataatagtg atatgacatc
     6061 agttgttcat cagctcacac aggccaatat tacttttagc gagattagac ataaccattt
     6121 gaatttagaa gaaattttct tacacttaac aggtaagaag ttacgagatt agaggttact
     6181 atggttttat ttcatttaat caaaaaagaa agtttacaga tttttagaaa ccgaacagcc
     6241 ttattgatga tggtgatttt tccaattttg atgatcgtta ttttaagttt tgcctttaaa
     6301 tcaagtttta atactgcgac aacagtccct aaattgacca ttcgttacca attagagggt
     6361 gaaaaaacgg attaccagaa aaattttctt gcttttttaa aagttttaaa ccaaaaactt
     6421 catttagaga ctaaacctag taattctctt gaaaaagatc gacaaagggt cagtgaagga
     6481 gccttaacgg ctgttttaga agtgaagaag aatcagacca ttaaggttat tactaataat
     6541 attaatcagc aaaatgcaga tttgatcaat atgctagtaa aaaattatgt tgataatgct
     6601 aaaacttatg actcgatagc agctctttat cctcaacaat taaatcatat cagaaagcga
     6661 agtgtggact atgttaaggt cagttcaata cagacaagta aaggaatgac atcagctgat
     6721 tattatgcta tttccatgtt taccatgatt actttttata gtatgatgtc tgcgatgaac
     6781 cttgttttgt cagatcgtca acaacggatt acaaatcgta ttcacttaac aggagtttct
     6841 ccaagttttt tggtctttgg gaaattaata ggtgctatgt tagcaacaac tgttcaattg
     6901 agtcttttat acatttttac aaggtttgtt ttacgagtta attggggcac taatgagtgg
     6961 atgcttattg gtataacagc ctccttagtc tatctctctg tagctatagg tatcgggcta
     7021 ggtataagca ttaaaaatga ggctttttta acggttgcat ccaatactat tattcctata
     7081 ttcgcctttt taggaggcag ttacgttcca ttgacaacat tacacagctc tattattaat
     7141 caattgtcga atatatctcc tattaaatgg gttaatgata gtttgttcta tcttattttt
     7201 ggtggtcaat ataatccgat tcctgtaact ttgatcgtta atattagtat cggaacaatt
     7261 tttataatat tggcattgat aggtatgaga aagcaggtga cgacatgatt tgttttataa
     7321 aaactctatt tgttaagata aagcgcaaaa aaacaagtta tgtgacattc tttttaatgc
     7381 ctattttaac gacacttttg gctttatctt tgagtttttc aaataataat caagctaaaa
     7441 ttgggatatt agataaagat aatagtcaga tatctaaaca atttattgct caactaaagc
     7501 aaaacaaaaa gtacgacatt tttaccaaaa tcaaaaaaga gcatattgat cactaccttc
     7561 aagataaatc tctagaagcg gtattgacta ttgacaaagg gttctcagat aaagtgttgc
     7621 aaggaaaatc tcaaaaactc aatatacgtt cgattgctaa tagcgaaatt acagagtggg
     7681 taaaggcaca gaccaattat ctattggaaa attataatat tataggggat gtggctctag
     7741 gtaacgaaga tacttttaat agaattctcc aaaaaaacca acagttaaat tatgatgtta
     7801 agcaagtaac tttgacagac cgatcacgta gcaaagcagt atcttccaca acgacaggat
     7861 ttttgcttat tctaatgtta ggtagtacga gcgtgattta cagtggtatt ttggcagata
     7921 aatctagtca gttataccat cgattaatgt tatcgaactt atctcgtttt cgctatatgt
     7981 tgagttacgt ctgtgtagga tttgttgctt ttacgattca aattgtcatt atgctgagtt
     8041 tgttaaaagt atttaatatt agtttttttg ttccgacatc acttcttttg attatttttt
     8101 tcctttttag tttattagcg ataggctttg gcctgctgat tggagctatc acacaaaatt
     8161 cccaacaaag tagccagtta gctaatctta ttgtaatgcc gacttcaatg ttggctggct
     8221 gtttatggcc attgtctatt acgccttctt atatgcaagc aattggtaag ttattaccac
     8281 aaaattgggt tttatcagcc atagctattt ttcaaagtgg agggacctta tctcaggctt
     8341 ggccatactt gttagctcta atgggaacag cactagcttt gattagtttt tcaagtttat
     8401 tattaaaacc taccaaacta taattagtct tttgttaaaa aatactttcc taattagcta
     8461 actaccaggt agccctttta ttggcttata tgcaataaaa gggttgcttt ttgcttatat
     8521 tttctctagt gcacttatct tttgttaaaa gtgattgcga tgttactgtt gttactgtgt
     8581 tttttagaga gcatattatc aaaagcgacc cctctataaa gttcgttttt gttgataaat
     8641 gggttgtcaa agtattttaa aaaacgtttt caataaacat aaaaactaat gttattaaaa
     8701 aaagttttga aaacgtattt attttatggg atgtttttgt tacaataagc atgtatcgaa
     8761 tgctataaag ctgtcttgtt cgctatcagg ggtgcttgtg atgttatgtc agatcaaaca
     8821 agtctttaat tgggtgactt aacagattaa aagaaaagat ctaatcgtgt tacttgatag
     8881 tataattaat gcaaacagaa agtgtatccc aattcatagt ctcaggtgga ggttaatatt
     8941 caaaaataaa atcttgttgt tgtcttaaac taatcacatt aaaaggagat atcatgatta
     9001 acaagaaatg tataatacct gtttcattgt tgacactagc tattacgctt actagtgttg
     9061 aagaagttac ttcacgccaa aatttgactt atgccaatga aatcgtaaca caaaggccaa
     9121 agagagaatc tgttattagt gataaatcga attttcccgt catatcacct tacctagcaa
     9181 gtgtggattt tggtgagaga aaaacacctt tgccaacacc tgataaagga gtaaaagtaa
     9241 ctactgaaca gtctattgct caagtaagaa aggggcctga agaaagaccc tatactgtta
     9301 ctggcaagat tacgagtgtg atcaatggct ggggaggcta tggcttttat attcaagata
     9361 gtgaaggtat tggactttat gtttatcctc aaaaagattt aggatacagt aagggagata
     9421 ttgttcaatt aacaggtaca cttactcgct ttaaaggtga tttacaactc caacaggtga
     9481 ctgcacacaa aaagttagag ttatcttttc cgacttctgt taaagaagca gtaatatcag
     9541 aattagaaac aacaacaccc tcaacattag ttaagttatc tcacgtgaca gttggagaat
     9601 tatcaactga tcaatataac aacacatctt tccttgtaag ggatgatagt ggtaaaagta
     9661 tagttgttca tatagatcat cgtacagggg ttaaaggggc tgatgttgtt actaaaataa
     9721 gtcagggtga tttgattaac ctcacagcca tattgtctat tgttgatggt caattacaat
     9781 taagaccgtt ttctcttgaa caattggaag tggttaaaaa ggtcacaagc tcaaatagtg
     9841 atgcttcatc tcgtaatatt gtgaaaatag gcgagattca aggagctagt catacgtcgc
     9901 cacttctcaa aaaagcggtc accgtagaac aggttgttgt cacttattta gacgattcca
     9961 ctcattttta tgttcaagat cttaatggtg atggtgattt agcgacttca gatggtattc
    10021 gtgtttttgc taaaaacgct aaggttcaag tcggcgatgt tttgaccatt tcaggtgaag
    10081 tggaagaatt ctttggtcgt ggttatgagg aacgtaagca gactgacctt accatcaccc
    10141 aaattgtggc taaagcagtg accaaaacag ggacagctca agttccatca ccgcttgttt
    10201 tagggaaaga tcgtatcgcg ccagccaata ttattgataa tgatggcttg cgtgtgtttg
    10261 atccagaaga agacgctatt gattattggg aatcaatgga aggcatgtta gtggcggttg
    10321 atgatgctaa aatccttggt ccaatgaaaa ataaagaaat ttatgtctta cctggctcta
    10381 gtacaagacc gttaaataat tcaggtggag tattacttcc agctaattct tataacacag
    10441 atgtgattcc tgttcttttc aaaaaaggca aacaaattat taaagcagga gactcttaca
    10501 aaggaagatt agctgggcca gtatcttata gctatggtaa ttacaaggtc tttgttgatg
    10561 acagcaaaaa catgccaagt ttaatggatg gtcatctaaa acctgaaaaa acaaacttgc
    10621 aaaaagacct tagcaagtta agcattgctt cttacaatat tgaaaacttc tcagccaatc
    10681 cttcttcaac taaagatgag aaggtcaaac ggattgccga atcctttatt catgatctga
    10741 atgctccaga cattattgga ttaattgaag tccaagataa taatgggccg actgatgatg
    10801 ggacaacgga tgcgacacaa agcgcgcaac gcctcattga tgctattaaa aaactaggtg
    10861 gcccaactta tcgttatgtt gatattgctc cagaaaataa tgttgacgga ggtcaaccag
    10921 gtggtaatat tcgaacagga ttcctttatc aaccagagcg cgtcagcctt tctgataagc
    10981 caaaaggcgg tgctcgtgat gctctaactt gggttaatgg agaattaaac cttagtgttg
    11041 gtcgaattga tccaactaac gccgcttgga aagatgttcg taaatcacta gcagcagaat
    11101 ttatcttcca aggtcgtaaa gtcgttgttg ttgcaaatca tttgaactct aagcgtgggg
    11161 ataatgctct ttatggttgt gtgcaaccag tcacttttaa atctgagcaa agacgtcacg
    11221 tcttggctaa tatgctagca caatttgcga aagaaggggc aaaacaccaa gctaatattg
    11281 tgatgctagg tgactttaat gattttgaat tcacaaagac gattcaatta atcgaagaag
    11341 gtgacatggt taacttggtg agccgacatg atatttcaga tcggtattct tattttcacc
    11401 aaggcaataa tcagaccctt gataatatat tagtttcacg ccatttactt gatcactacg
    11461 aatttgacat ggttcatgtg aattccccat ttatggaagc tcacggacgc gcatcagatc
    11521 atgatccatt gttacttcaa ttatcatttt ccaaagaaaa tgataaggca gagtcttcta
    11581 aacaaagtgt aaaagctaaa aaaacttcaa aaggaaaact gttgccaaaa acaggagata
    11641 gtcttgttta tgtgataacg ctactaggaa cggctagttt attagtgcct attttattat
    11701 tgactaaagg caaaaaggaa tcatagcgat ttgaagaatt gcagttcata aagagtcgtt
    11761 aaaggtttga tatacttacg ttagatctta agctaaaatg gatgactata taaaaactaa
    11821 gattgataac aaaagaagat aacaataaga cagctttact tgctaaagac ttttgtcaag
    11881 ctaattgttt tatggtacaa tgtaaccgtt gctttgcaac ccttggtgct tagttccctt
    11941 tcaccaagca tattagaaac gtagatagct tttgagagtt atccagacgt taaaggagaa
    12001 aaaatgacaa aattgactgt acacgactat gttcacattg ggctagtagc tgccttgtat
    12061 gttgtcttaa ctattacccc gcctttaaat gcgatttctt atgggatgta tcaatttaga
    12121 atatctgaaa tgatgaattt cttagctttt tatcatcgca agtatattat tgcggtgact
    12181 cttggatgta tgattgctaa cttttatagt ttcggactga ttgatgtctt tgtaggcggc
    12241 ggttcaactc ttatttttgt gaccttaggt gttattttgt ttagtaagta tcaaaaagat
    12301 tatcttttta atggtatttt taataaagct tttgtttact tttctttctt ttttgcaact
    12361 tccatgttta ctgtagcaat cgaactttac ttctttggag caccattttt attaacatgg
    12421 tttacaactg cgttaggaga attagtatct ctgctcatag gatcacttat tattgataag
    12481 ttgtctcaaa gaatttcctt ttagtaatgc atcatactca aaagagttgg gtcaataccc
    12541 ttctcttttt tatgttgttt gtaatgttaa aatcgttcta gatagaaata tttaacactt
    12601 tagctaatag taccatatgg agtggccaac gattactttt gatgttgtta tgatatagaa
    12661 atagctcatt tgttatcttt tatgataaaa taaaagtatg aaaaaacgca taaaagaatt
    12721 aacagatctt cttaaccgtt accgttatga ctattatact aaagatgccc catcagtttc
    12781 tgacagtgac tatgataagc tttatcgtga actggtgact ttagagcagt catatcccga
    12841 gtatgtcttg caagatagcc caacgcagca ggttggaggg actattttaa aggggtttga
    12901 aaaatatcga catcagtatc cgctttttag tttgcaggat gctttttcac gtgaggagct
    12961 ggatgctttt gataagcgcg tcaaggccga atttccgaat gccacctatc tagcagagtt
    13021 aaaaattgat ggtttatcta tttccttgag ttatgagaat ggcttcttac aggttggagc
    13081 aacacggggt gatggcaata tcggtgaaaa tatcacagaa aatatcaaaa aaataaagga
    13141 tattccttac caattgagtg agcctttaac catcaccgtt cgaggagagg cttacatgtc
    13201 tcgtcagtcc tttaaagcga tcaatgaagc acgccaagaa aatggggaga ctgaatttgc
    13261 taatcctaga aatgctgccg ctgggacact aaggcagcta gatacgtcag tggttgctaa
    13321 gcgtcaacta gccacttttt tgtatcaaga agctagtccg acagctagaa atcaacaaaa
    13381 tgaggtctta gcagaattag cagatctagg tttttcagta aatccgtatt atcaactcac
    13441 atcgtctatg gatgagattt gggattttat caaaactatt gaggcaaaaa gagatcaatt
    13501 agcttatgac atagatggcg ttgttattaa agttaatagc ctagccatgc aagaagagct
    13561 agggtttacg gttaaagctc cacgctgggc cattgcttac aaatttccag cagaagaaaa
    13621 agaggcagaa atcctttcgg ttgactggac agtgggacga acaggcgtgg tcacacctac
    13681 agcgaatcta actcctgtgc aactagcggg gacaaccgtg agtcgtgcaa ccctacataa
    13741 tgtggattat attgccgaaa aagatatccg tattggcgat acagtgattg tatataaggc
    13801 aggggacatt attcctgctg tcttaaatgt cgttatgagt aagcggaacc agcaagaagt
    13861 catgcttatt cctaaactat gcccatcttg tggtagtgaa ttagttcatt ttgaagatga
    13921 ggttgctttg cgttgtatta atccgttgtg tcctagtttg attcagcgaa gtttggagca
    13981 ttttgcaagt cgtgatgcca tgaacattac tgggctggga ccagctattg tggaaaaact
    14041 atttttagcg gggtttgttc atgatgttgc tgatatttac cagttgacca aagaagattt
    14101 catgcaatta gatggcatca aagaaaagtc agctgataaa ttgctcgctg cgattgaggc
    14161 ttctaaatca aattcagctg aaaaactgtt atttggtcta ggaattcgtc atattggctc
    14221 taaggttagt cgcttaattt tagaggtata cggagatatt tctgctcttt taaccgctaa
    14281 agaagaggaa atcgcaagga tagatggtct tggctcaacg attgctcaat cacttactca
    14341 atactttgaa caaaaaacgg ctgcgatttt agtagacgag ttaaagacag caggtgtcaa
    14401 catgcattac tcaggtcaaa aagttaatag tgacgcagcg ctttttggtc taactgttgt
    14461 tttaactggc aaattaaatc agctgaaccg aaatgaggcc aaagataaat tagaggcatt
    14521 aggtgccaaa gttactggaa gtgtatctaa gaaaacagat ttagttattg caggtagtga
    14581 cgctggttct aagctagaaa aagcaaagag cttaggaatt cggattgaag atgaagattg
    14641 gctacgccag ctttaagtga ggtaatgtta tgaaaaaaca attgagagca cgtctcattt
    14701 ataatccaac gtcaggacaa gaacttatga gaaaaagtgt tcctgaagtt ttagacatat
    14761 tagaagggtt cgggtatgaa acatctgcct ttcaaacaac agcccaaaag aactctgctc
    14821 taaatgaagc aagaagagcg gcaaaggcag gttttgactt attgattgct gctggaggtg
    14881 atggcactat taacgaagtg gtcaatggaa ttgctccctt gaaaaagcgc cctaaaatgg
    14941 ccattattcc aacaggtacc actaatgatt ttgctagagc attaaaagta ccaagaggaa
    15001 atccgagcca agcagcaaaa cttatcggaa aaaatcagac tatccagatg gatattggta
    15061 gagctaagaa agatacttat ttcatcaata ttgctgcagc aggaagtttg acggaattaa
    15121 cttacagtgt accaagtcag ttaaaaacga tgtttggata cttggcttat cttgctaaag
    15181 gagtagaact gctcccaaga gttagcaatg tgcctgttaa aattacgcat gacaaaggcg
    15241 tctttgaagg tcaagtttct atgatttttg cagctattac caattctgtt gggggatttg
    15301 aaatgattgc tcctgatgca aaactagatg acggtatgtt tacgctcatt ttaataaaga
    15361 cagcaaatct ttttgaaatt gtacatcttt tgcgtttgat tttggatggt ggtaagcata
    15421 ttacagatcg ccgtgtcgaa tacattaaga ccagtaaaat agtcattgaa ccccaatgtg
    15481 gtaagcgaat gatgattaat ttagatggcg agtacggagg agatgctcca attacattag
    15541 agaacctaaa aaatcatatc actttttttg cagatactga tttgatttct gatgacgctt
    15601 tagtcttaga tcaggacgaa ttggaaattg aggaaatcgt aaagaaattt gctcatgaag
    15661 tagaagactt aggacaagaa ttagaagaat aatacaatag ttattagcta ctgacagttt
    15721 agtcaaatgc actactatct agaatctaag atttttaaat caattgaggt agtgtttttt
    15781 gatgcgctca aagagtcaat ttattcatat gaggggccta tttgaggtct ctcttttttg
    15841 atcatatgca agaaaatgcc atgttttagg ggtgttatta tacccttttt ggaatcttgt
    15901 tgcctttttg ttataataag agtgtaattc tatttttaaa aagatcttaa caaagacaga
    15961 ctcgtttatc aaaaaggtta gtattagtct aagaaagcgt acccagacta aagaaatctg
    16021 ttgacattct taattttaag gaatagaata gcaaagtaaa aaaaatttta aggagtattc
    16081 tactatgaat cctattttcg cattggcttt ggcctgtttt ggtgtttctc ttgctgaagg
    16141 tttcttgatg gcaaatcttt tcaaagcagc ttctcgccaa ccagaaatca ttggtcaatt
    16201 acgttcatta atgatcttgg gtgttgcctt tatcgaaggt actttcttcg ttacccttgt
    16261 tatggccttc attcttaaat aacagcctat tttataatag aaaaggaggg tgttagatgg
    16321 aagaagctaa aatacctatg ctgaagcttg gtccaataac ctttaatttg accctacttg
    16381 ctgtttgtat tgtcacaatt gcgattgtct ttgcctttgt tttttgggca agtcgccaaa
    16441 tgaaattgaa accagaaggg aagcaaactg ctttagaata tttaatcagt tttgtggatg
    16501 gtattggaga agagcactta gatcataatc tacaaaaatc ttattcgctg ttactcttta
    16561 ccatttttct ctttgtagct gtcgctaata atttagggtt atttactaag ttagagacag
    16621 ttaatggcta taacctatgg acctcgccaa cagccaatct ggcttttgac cttgctctat
    16681 ctctttttat taccttaatg gtacacattg aaggggttag acggcgtggc ttggttgccc
    16741 atttgaaacg tttggctaca ccgtggccaa tgactccgat gaatttatta gaagagttca
    16801 caaatttctt atcacttgcc attaggttat tcggtaatat ctttgccggg gaagttgtta
    16861 caggtttgat tgttcaactg gccaattatc gagtttattg gtggccgatt gctttcctag
    16921 tcaatatggc gtggacagcc ttttcagtct ttatttcctg catacaggct ttcgttttca
    16981 caaaactgac agcgacctat ctaggaaaga aagtcaatga atcagaagaa taaggaagga
    17041 gaacaaacga atgtcaatca catttggtga actcgttggg aattttattc tagtaacagg
    17101 ttctgtaatc gtcttgttac tcttgatcaa aaaattcgct tggggtgcga ttgaatcgat
    17161 tttacagaca cgctcacaac aaatctctcg agatattgat caggctgagc aatcacgtct
    17221 aagtgctcaa cagttagagg caaaaagtca agctaaccta gatgctagtc gtttacaagc
    17281 aagtaaaatc attagtgatg ccaaagaaat tggtcaatta caaggtgata aattggtggc
    17341 agaagctact gatgaagcaa aacgcttgaa agaaaaagcg ttgacagata ttgaacaaag
    17401 caaatcagac gctatttcag cagtcaaaac agaaatgtct gatttaacgg ttcttttagc
    17461 ggaaaaaatt atgggagcca atcttgataa gacggcgcaa agccagctta ttgacagtta
    17521 tcttgatgac ttaggagaag cttaatgacc aaaaaagaac aggctcttat cgagcaatat
    17581 gcaaaaagcc ttgttgaggt ggcgagtgaa catcattctc ttgatgcctt acaagctgat
    17641 gtgcttgcga ttttagagac gtttgtaaca actaatcttg atcaaagtct atcaagtcaa
    17701 gctgttccgc atgctgaaaa aataaaattg ctaaccttat taaagggaaa taattctgtt
    17761 tatatgaata atttcttgaa tctcatttta caaaacgaac gtgaagctta tttgtatcaa
    17821 atgcttcagg ctgttttaaa tgaaattgca atagtttcaa atcagtatga tgtgactgtt
    17881 acctcatcac tacctttgac tgaggagcaa aaaagccgtg ttcgagcagt tgttgcaaag
    17941 aaatttgctg taacagcggg tcgtttaatt gaaaaagtag atccttcgct tattggagga
    18001 tttattatca gcgtcaataa taaagtaatt gataccagta ttcgtcgtca attgcaagca
    18061 tttaaaatga atttaaaata gaaagtggtg tgacttttgg caattaatgc acaagaaatt
    18121 agcgctttaa ttaaaaagca aattgagaac ttccagccaa atttcgatgt cacagaaact
    18181 gggatcgtta cctatattgg tgacggtatt gcacgtgccc gtggattaga taatgccatg
    18241 agtggtgaac ttcttgaatt tgaaaatggt gcctacggga tggctcaaaa ccttgagtca
    18301 aatgatgtgg gtattattat tcttggtgat ttttcagcaa tccgtgaagg agatgtggtt
    18361 aagcgcaccg gtaaaatcat ggaagtacca gttggtgaag ctctcattgg acgtgtggta
    18421 aacccacttg gacaaccagt tgatggcttg ggagatattg aaacaactgg ctttagacca
    18481 gtagaaacgc cagctcctgg tgttatgcag cgtaaatccg tttctgaacc cttacaaact
    18541 ggattaaaag caattgatgc tttggttcca attggtcgtg ggcaacgtga gttgattatc
    18601 ggagaccgtc aaacaggaaa aacatccgta gctattgatg cgattttgaa ccaaaaaggt
    18661 caagacatga tttgtatcta tgtggctatt ggtcaaaaag aatcaaccgt tcgtacacaa
    18721 gttgaaaccc ttcgccgtta cggtgccttg gattatacta ttgttgtgac agcgtcagcc
    18781 tcacaaccat caccattgct ctttatcgct ccttatgcgg gtgttgccat ggctgaagaa
    18841 tttatgtacc aaggcaagca tgtcttgatt gtctatgatg atttatcaaa acaagcggtg
    18901 gcttatcgtg aattgtctct cttgcttcgt cgtccaccag gtcgtgaggc ttacccaggg
    18961 gatgttttct acttgcatag ccgtcttttg gaacgctctg caaaagtttc tgatgactta
    19021 ggtggaggtt ctatcacagc tctaccattt atcgaaacac aggccggaga tatctctgca
    19081 tatattgcga ctaacgttat ttcgattaca gacggacaaa tcttcttgca agagaacctc
    19141 tttaattcag gaattcgtcc agcgattgat gcaggatcat ctgtctcacg tgtaggtggt
    19201 tccgctcaaa ttaaagcgat gaaaaaggtt gctggtactc ttcgtttgga tttggcttcc
    19261 tatcgtgaat tagaagcctt tacccaattt ggttcggacc ttgatgctgc aacacaagca
    19321 aaacttaatc gtggtcgccg tacggttgaa atcttgaagc aaccattgca taaaccgtta
    19381 cctgttgaaa agcaagtcgt tattctttat gcccttactc atggtttctt agatgatgtt
    19441 cctgtagatg atattttggc ttttgaagaa gctctttacg actactttga cgttcattac
    19501 aatgatttat ttgaaactat ccgtaccaca aaagaccttc ctgaagaagc tgcccttgat
    19561 gccgctatta aagcgtttaa agaacactca aactttaagt catagaggga ggatactagt
    19621 atggcaggct ctctaagtga aattaaagct aaaattattt caactgagaa aacaagtaaa
    19681 atcactagtg ccatgcgtat ggtttcttct gcaaaacttg ttaaatctga gcaagcagct
    19741 cgtgattttc aaatttacgc ctcaaaaatt cgccagatta ctacagattt attgaaatca
    19801 gaattaacca taggatctga taatccgatg ttggtgtctc gtcctgtcaa aaaaacaggc
    19861 tatattgtca tcacgtctga taaaggactt gttggaggtt acaattcaaa aatcttgaaa
    19921 tctgttatgg atatgattac agagtaccat gctgatggtg actatgaaat catttctatt
    19981 ggtagtgttg gttcagactt cttcaaagca agagggatga atgtggcttt tgaacttcgt
    20041 ggacttgcgg atcaaccaag ttttgaacaa gtgagacaaa tcatttcaca atccgttgac
    20101 atgtttgtca atgagatttt tgatgagtta tatgtctgtt acaatcacca tgtgaatagc
    20161 ttaaccagcc aagtccgtgt tcaacagatg ttaccaattt ctgacttggt tgctgatgaa
    20221 gcagcagaag aaggtgttac tgggtttgaa ttggaaccta atcgtcatga tattttagat
    20281 caattgttac ctcaattcac agaaagttta atttatgggg ctatcattga tgctaaaacg
    20341 gctgaacatg cagcaggtat gactgccatg cagacagcaa ctgataacgc taagaatgtc
    20401 attaacgatt tgaccatcca atataaccga gctcgtcaag cagcaattac acaagaaatt
    20461 actgaaattg ttgcaggagc aaatgcacta gaataaaaaa taacgctgac tagcgattag
    20521 gttattgtca gcattcaatt ttatcaatcg agataaaatg acttatggga cttttctatt
    20581 gaaagactgc tcttttcagt ataaaagaag ttagcaagac taactaagcc ctgactatcg
    20641 aatataagga gaaatgaatg agctcaggca aaattgctca ggttgttggt ccagtagtag
    20701 acgttatgtt tgctagcggg gacaaacttc cagagattaa taatgcattg attgtttata
    20761 aagatagtga taaaaagcaa aaaatcgtcc ttgaagttgc tctggaactt ggtgacggta
    20821 tggtgcgaac aatcgctatg gaatcaactg atgggcttac acgtgggtta gaagttcttg
    20881 acactggtcg tgcgattagc gtaccagtag gtaaagaaac tttgggacgc gtctttaatg
    20941 tacttggaga aaccattgac ttggaagaac catttgcaga agacgttgac cgtcagccga
    21001 tccataaaaa agcaccatcg tttgatgaat tatcaacatc atcagaaatt cttgaaactg
    21061 gtatcaaggt aattgacctt cttgcccctt accttaaagg tggtaaagtt ggacttttcg
    21121 gtggtgccgg agttggtaag actgtcctta tccaagaatt aatccacaat atcgcccaag
    21181 aacacggagg tatttcagta tttaccggtg ttggtgagcg aacacgtgaa ggaaatgacc
    21241 tttactggga aatgaaagaa tcaggcgtta ttgagaaaac tgccatggtt tttggtcaaa
    21301 tgaatgagcc gcctggggca cgtatgcgtg tagcccttac tggtttaacc attgctgagt
    21361 atttccgtga tgtagaaggc caagatgttt tgctctttat tgataatatc ttccgtttca
    21421 ctcaggcagg ttcagaagta tcagccctct taggccgtat gccttctgct gttggttacc
    21481 aaccgaccct tgctactgaa atgggacaat tgcaagaacg tattacgtca actcaaaaag
    21541 gatctgttac ttctatccaa gcgatttatg tgccagccga tgactatact gacccagcgc
    21601 cagcaactgc atttgctcac ttggattcaa caactaacct tgagcgtaaa ttgactcaaa
    21661 tgggtattta ccctgcggtt gacccattgg cttcaagttc acgggcctta tcacctgaaa
    21721 ttgttggtga agagcactat gctgtggcaa cagaggttca acgtgtactt cagcgctacc
    21781 gtgaattaca agacatcatc gctattttgg ggatggatga attatcagat gaagaaaaaa
    21841 cattggttgg acgtgcgcgt cgtatccagt tcttcttatc acaaaacttt aatgttgctg
    21901 aacaatttac aggtcttcct ggttcttacg tgccagttgc tgatacagtt cgcggcttta
    21961 aagaaattct tgaaggaaaa tacgatgaac ttccagaaga tgccttccgt tcagttggtc
    22021 caatcgagga tgtgattaaa aaagccgaaa aaatgggctt ttaatgaggt gatgccatga
    22081 cacaaatgac tgttcaagtg gtaacgccag atggaatcaa atatgatcac catgctaaat
    22141 ttatttcggt aacaacacca gatggggaaa tggggatttt acctaatcac atcaatttga
    22201 ttgcaccttt gcaagttcat gaaatgaaaa ttcgccgagg tggtgaagat gaaaaagtgg
    22261 actggattgc aatcaatggt ggtattattg aaatcaagga taatgtggtt accattgtcg
    22321 ctgattctgc agaacgtgac cgtgatatcg atgtcagccg agcagagcga gcaaaactaa
    22381 gagcagaacg tgaaattgca caggctgaaa caacccataa tattgatgag gttcgtcgtg
    22441 ccaaggttgc cttgcgccgc gctttgaatc gtatcaacgt tagtaaaaaa taagtggtgt
    22501 tgataaaaga caaggataag taagaaaggt ttttaaccta ttattttgtt tactgattct
    22561 ttttaacatc agtttctgag agtttgacca tactaccttc tctaaacacg ttattattgt
    22621 tgagaggagt tatatggggg aactcttttt tgtatccacg ttgttagtag aaactcagta
    22681 atgacgctta atatattttt aggctatcaa cttagtcaga gaagatgtca acttaattga
    22741 taagttggac ggatcaagat ggtatgttat aataatccta tggaattatt aatgaagatc
    22801 attgcctttt cgtgtcattt attttttatt ggccttagtt accaattatt gattagtgtg
    22861 attgactgga caaaatttag tcattatcat ccagaaaatc ttggccggct acgacttttt
    22921 gtctttttat tagctactgc cctagggtat ttggtgagcc attgtatgct ggaattgctt
    22981 caaattagcc agacgctctt ttttgagttc cgctaatact ggaataaaag aagtatggta
    23041 taattttact acgactaaga gatagataag ggagaaaatt gtggataaaa taatcattga
    23101 aggtggtcaa acacgcttag aaggagaagt tgttattgag ggtgctaaaa acgcagttct
    23161 tcctttactg gcagcatcta ttttaccttc aaaaggaaaa acaattctta gaaacgttcc
    23221 tattctatct gatgttttta ccatgaataa cgtggtacgt ggtttagata ttcgtgttga
    23281 ttttaatgaa gcagctaacg aaatcacagt tgatgcctca ggacacattt tagatgaagc
    23341 cccttacgag tacgtgagcc aaatgcgtgc ctctattgtt gttttaggac caattttggc
    23401 acgtaatggc cacgcaaaag tatcaatgcc tggaggctgt acgattggca gtaggcctat
    23461 taatttgcac ttaaaaggat tagaggctat gggggcaacg attactcaaa aaggtggaga
    23521 tattaccgct caagcagatc gactgcaagg tgccatgatt tatatggact tcccatctgt
    23581 aggagctacc caaaacttga tgatggctgc cactttagct gatggtgtga ccactattga
    23641 aaatgctgct cgtgagcctg aaattgttga tttagctcaa tttttgaata aaatgggagc
    23701 tagaattcgt ggtgctggaa cagagacgtt aacgataaca ggtgtcacgc atttacgagg
    23761 cgtagaacat gatgttgttc aagatcgtat agaagccggt acatttatgg ttgcagcggc
    23821 gatgacttca ggcaatgttt tgattagaga tgctgtttgg gaacataatc gtccattgat
    23881 ttcaaaatta atggaaatgg gtgtttctgt aacagaagaa gaatacggta ttcgcgttca
    23941 agcaaacacg ccaaagctca aacctgtaac ggttaaaacc ttgcctcatc caggttttcc
    24001 aacagacatg caagctcaat ttacagcttt aatggcagtg gtcaatggag agtctactat
    24061 ggttgaaact gtctttgaaa atcgatttca acatctggaa gaaatgcgac gcatgggctt
    24121 acaatctgaa atccttaggg aaactgccat gattcatggt ggaagacaac tgcaaggtgc
    24181 tcctgtgatg tcaacagatt tacgtgccag tgctgccctt atcttgacag ggattgttgc
    24241 tcaaggagtt acaatagtta ataatttggt tcatttagat cgtggctact atcaatttca
    24301 tgaaaaatta gcaaagcttg gagctactat tagtcgtagc agtgaggtct agcttatgac
    24361 aaatggttta aaatatgtct tagaacaaat gttattactt ttcataattg ctgccttggc
    24421 gtgtcttttt ttagccattg gacttatgat tggttatagt tttatgggag atggccagag
    24481 tccatggcat attttatcta tggataagtg ggcagagtta gtgaataaat ttactggaaa
    24541 gtaggccttg cctacttttt atagcatctg agaggaagta tgttaacaag gaaaaaacga
    24601 aaaagggtgc aagagcaaaa ggttcctaaa agagctaatg ccttacttac taagtcgaca
    24661 cgacagtatc gaaatcgcta tcaaacggat aatgcttatc gtaactttaa gccagcaggt
    24721 tggcaccgat tgcaccactt aaaaggaagt tatgatcacg cggttgatag agggcatttg
    24781 ctaggttatg ctttagttgg tggactgaaa ggttttgatg cttctactgg taatcctgat
    24841 aatattgcca ctcaactaag ttgggctaat caagcaaata aaccctactt gacaggtcag
    24901 aattactatg aaggtttagt acgtcgtgct ttagataagg ggcatcgcgt ccgctaccgt
    24961 gtcaccctac tttatgatgg tgataatcta ctagccagcg gtagccattt ggaggctaaa
    25021 tcctctgatg acagcttgac ttttaacgtg tttgttccaa atgtccaagc aggattgacc
    25081 gttgactatc ggacgggaca aatagctatc aatctctaag cgaaaagtca ctgatttaag
    25141 attgtcacta agcacttttt ttgatagaat agaactaatt gaataagtgt ctatgagact
    25201 agtactaata gagaaattaa cagggagtga gggccgtgac tggaagcctt cttaagggaa
    25261 ctattaggaa ttcactcagc taaagacaat taattaaggt ctgataacgt cagataaaaa
    25321 cggatggtac cgcgtgtcaa cgctccgctt atcaagtgga ggagtggcat gcttttttca
    25381 tcgccaaaag aagggaaaac tatggattta caagcacaat tagaggaatt aaagacaaaa
    25441 acattggaga ccttacagtc tttgacgggt aatcatacca aagaactgca agatttgcgc
    25501 gtggctgttc ttgggaaaaa gggatctttg acagaattac taaaggggct aaaagacttg
    25561 tctaatgact tgcgtcctgt ggttggtaaa caggtgaacg aagttcgtga cttattgaca
    25621 aaagcctttg aagaacaggc taaaattgta gaagctgcta aaattcaggc ccaacttgat
    25681 gctgaaagca ttgatgtgac tttaccgggt cgtcaaatga ctctggggca tcgtcatgtg
    25741 ttaacacaaa ccagtgaaga aatcgaagat attttcttag gaatgggttt tcagattgtt
    25801 gatggctttg aggtggaaaa agattattac aactttgagc gcatgaattt gccaaaggat
    25861 caccctgccc gtgacatgca agatacgttt tatatcacag aagaaatctt gttacgaact
    25921 cacaccagtc ctgtgcaggc ccgtactctt gatcaacatg atttttcaaa agggccttta
    25981 aaaatggttt ctccaggtcg tgttttccgt cgtgatactg atgacgctac ccactcacat
    26041 caattccatc aaattgaagg tttggttgtg ggcaaaaata tttccatggg agacctcaaa
    26101 gggacccttg aaatgatcat caagaagatg ttcggtgacg aacgtagcat tcgtttgcgc
    26161 ccgtcatatt tcccgttcac agaaccatct gttgaagtgg atgtttcttg ctttaaatgt
    26221 ggtgggaaag gctgtaatgt ctgcaagaaa acaggatgga ttgaaattct tggtgctggt
    26281 atggttcacc caagtgtctt ggaaatgtca ggtgttgatg caaaagagta ttcaggcttt
    26341 gcctttggtt taggtcaaga gcggattgcc atgttgcgtt atggcattaa tgacattcgt
    26401 ggtttctatc aaggcgacca acgtttctct gaacaattta actaaaacga gtcgtttgaa
    26461 gacctctgtc agctatttta tctaagattg agtgaaagtt gataggtaat gataataggt
    26521 taattgtcta aggggaaagt ccctctcgct tcaacgtcat aagggttttg acttggaact
    26581 taaaatacga aaggaaatga ctcaaatcac ggcttgagag ctttctctag ccgagtgatt
    26641 tgggcactaa aattatgtta gtatcttata aatggttaaa agaattagta gatatcgatg
    26701 tgacaccagc agcacttgct gagaaaatgt cgacaacggg tatcgaggta gaaggaattg
    26761 aagtccctgc agatggttta tcaaaactgg ttgtggggca tgtgctttct tgtgaagatg
    26821 tgccagagac acatttgcat ttgtgtcagg tagatacagg tgatgaaacg ccacgtcaaa
    26881 ttgtgtgtgg cgcaccaaat gtgaaagcag ggattaaggt tatcgtggct gtgccaggtg
    26941 ctcgtattgc ggataactat aaaatcaaaa aaggcaaaat ccgcggcatg gaatctcttg
    27001 gcatgatttg ttccttgcaa gaacttggtt tgtcagatag tattattcca aaagaatttt
    27061 cagatggtat tcaaatcttg ccagaggagg ctgtgccagg tgatgctatt tttaaatacc
    27121 tggacttgga cgatcatatc attgaattgt ccattacacc taaccgtgct gatgcgcttt
    27181 ctatgcgagg tgtggcacat gaagtcgcag ctatttatgg caagtcagta tcattccccc
    27241 aaaaaaatct acaagaatct gataaggcaa cttcagaagc cattgaagtg gccattgcct
    27301 ctgataacgt tctaacttac gctagccgtg tcgttgaaaa tgtcaaagtt aagccaagtc
    27361 cacaatggtt gcaaaacctt ttaatgaatg ctggtattcg tcctattaat aatgtggttg
    27421 atgtgaccaa ctatgtgctc ttgtattttg gtcaacctat gcatgctttt gattatgata
    27481 aatttgaaga ccataagatt gtggcgcgtg cggctcgtca aggagaaagt ttggtcacac
    27541 ttgatggtga aaaacgggat ttgaccactg aggatcttgt tattaccgtg gctgacaaac
    27601 cagttgcttt agcaggtgtt atgggtggtc aagccactga aattgatgcc aactctcaga
    27661 cggttgttct tgaagctgct gtttttgatg gcaaatcgat tcgtaaaacc agtggtcgtt
    27721 taaaccttcg ttcggaatcc tcttcacgtt ttgaaaaagg ggttaactat gcaactgttt
    27781 tagaagcact tgactttgca gcggctatgt tacaagaatt agcagaaggt caagtcttat
    27841 caggccatgt tcaagctgga caattgccaa cagaacctgt tgaagtctca actagccttg
    27901 actatgtgaa tgttcgttta ggaacagaat taacttttgc tgatattcaa aggatttttg
    27961 accaacttgg atttggtcta acaggagatg aaacaagctt cacggtagct gttcctcggc
    28021 gtcgttggga tgttagcatc ccagctgact tggtggaaga aattgcgcgt atctatggtt
    28081 atgataagtt gccaacaacc ttaccagagg cagggggaac ggctgcagaa ttaacgccaa
    28141 cacaggctct tcgtcgtaaa gtccgtggct tagcggaagg attgggcttg actgaaatca
    28201 tttcgtatgc tttgacaaca ccagagaaag ctgttgagtt tgcagtggca ccaagtcacc
    28261 tgacagaact catgtggccg atgtctgtgg agcgttcagc actacgtcaa aatatggttt
    28321 cagggatgtt agatacggtt gcctataatg tggctcgtaa acaaagtaac ttggctcttt
    28381 atgaaattgg aaaaatcttt gaacaagaag ctaatccaaa agaagacctt cctaatgaag
    28441 tgaaccattt tgcttttgct atttgtggct tagtggcaca aaaagatttc caaacccaag
    28501 ctcaggcagt ggatttttac catgctaaag gtaacttgga tactttattt gcaaacctta
    28561 acctcaaggt tcaatatgtg ccaaccaaag acctagcaaa catgcaccca ggacggacag
    28621 cgcttatcct attagatgag caagtgattg gatttgttgg tcaagttcat ccaggaacag
    28681 caaaggctta tagtattcca gaaacctatg tggcagaatt ggatatggct gctttagaag
    28741 cagcgttgcc aagtgatcaa acttttgcgg aaatcacaaa attccctgct atgacacgtg
    28801 atgttgcctt gttacttgac cgtgaggtga gtcatcaggc cattgtaaca gctattgaat
    28861 cagcaggtgt aaaacgcttg actagcatta aactctttga cgtctatgaa ggagcaacca
    28921 ttcaggctgg caaaaaatca atggcttata gccttacttt ccaaaatcca aatgacaatt
    28981 taacggatga agaagttgcc aaatacatgg agaaaatcac caaagcattg acagaacaag
    29041 tcggtgctga agtacgctaa gaaaaaaact gggcctctaa ggctccgttt ttttctgtta
    29101 taatagagga aaaaagaact ccagttcaaa tgattggaga aaaacatcag aaggtggagg
    29161 aaaatcagaa tgtatcaaac aaaaataaca ggcaaccgcc tttaccacac ggtttcgaaa
    29221 ggctacggag atagtgtgac cttatttgga aaaactgatc aaggggaaac ccctatgagt
    29281 ttactggtta tcgccttgtc ttcttgtgtg actatgtgtg tgcagggttt ttaccatcgt
    29341 caatttcagc aagacacact tgctgtttct gttgaggcta gttatgagga agaagttttt
    29401 gaactacttg ttaggattga tgatgtttta gatgacaaaa agaaagctga tttattggct
    29461 tacattggaa cttattgtcg tgtgaaacaa ctcctcaaac ctgaagttac ggtgaccatt
    29521 acgttggaag gactgtctca tgtctgatgc tagtttgaaa acttaccaaa aacaatgggc
    29581 ttatcaaaag tattgggtca tggcacactc acagcagcat tacaatgctt taagagaatt
    29641 gtttaaagga aatcagtggt cagaagaaaa ggtgttgact tttcattgtt tgattgaaga
    29701 agcgcaagcc attcctccca cagtaaaaag cttacgaacg gcatatcagc atgtttgggg
    29761 gtattttaaa aaggtagcga gtcaggaaga aaaagaccat ttcaaagatt tggatgctca
    29821 gttggaaact aaatctgagg agatgctatg ctttttacaa gagatgactg ctcattatca
    29881 gccctcttat ctgctatctt gccgtttgat taccaaaggt ccttaaatgc taaacagaaa
    29941 agtagggatt tctgggaagt tatgctaagc tagtgatata aataaggggg aatgagagat
    30001 gtttttagcg cttaatgaaa tgaaacaatc caaattgcgg tatggtttga ttgctggttt
    30061 gctatgtttg gttgcctatt tgatgttctt tttgtcagga ttggcctttg gtttgatgca
    30121 ggagaaccgc tcggcggttg atctttggaa agctgacagt gttttactag ccaaggatgc
    30181 tgacgctacc ttgaccttat cacaggtgtc cagagctcaa gaaaatcaaa taacagcaga
    30241 caaggtagct cctcttgctc aactcaatac cgtggcgtgg tcagttaaaa atcctaagga
    30301 tgccgacaaa gttaaggtta gccttttcgg gattgattct aatagcttta ttcgtcctaa
    30361 cattgtaaaa ggtcgattat ttaagactaa caaagaggtt gttttggatc aaagccttgc
    30421 aaaagaggaa gcttttgcga ttggcaagga cttttacaca tcgagttcta gtcaagcatt
    30481 aactatcgtt ggttatactc aaaatgctag atttagtgtt gcaccagtgg tttatatgaa
    30541 tttggaagct tttgaaacat taaaatatgg agaaccacta ccaaaagata agcaagttgt
    30601 taatgctttt atcactaaag gaagtttaac agattatcct aaaaaagact tccaaaaatt
    30661 agatattaaa acctttatta ctaaattacc tggttatagc gctcaacttt taacttttgg
    30721 ctttatgatt agttttcttg tcattatttc agctattatt attggtattt ttatgtatat
    30781 tttgactatt caaaaggcac ctatttttgg gattatgaaa gcgcaaggaa tttctaacaa
    30841 aacgattacg accgctgtgc ttatgcagac attctttttg agttttttag gtagtggttt
    30901 agggttgcta ggtacttggc tgacatcatt attattacca acagtagtac cttttcaaag
    30961 caattggttt ttgtatttgg ctatattcgt tagtatgatc tgttttgctc tattaggcac
    31021 cttattttct gtttttaaca ttatacgaat tgatcctttg aaagcaattg gataggaggt
    31081 agtgatgtcg gttttaacat ttaaacaagt gaccaaaaca tttcaagatg gtcatcacga
    31141 aatcaacgca ttaaaggcaa ctgacttttc cattgaagct ggagaatttg tggctattat
    31201 tggaccatca ggttctggaa aatcaacctt tttgaccatt gctggtggct tacagacccc
    31261 aagttctggt cagctaatca ttgatggcac tgattatacg catttatcag aaaaagagcg
    31321 ctcacgcttg cgcttcaaat ccgttggttt tatcttacaa gcttccaatc tgataccttt
    31381 tttaacggtc cagcagcagt tggaattggt cgatcatttg acaggaagca aagaaaaagc
    31441 caaagccaat cagttatttg acgatttagg cattacaggg ctaaaacatc agttacctca
    31501 agaattatcc ggcggagaaa ggcaaagagc ggctattgcc cgtgctcttt accatgatcc
    31561 agcactgata ttggcagacg aacctactgc aagtttggat actgaaaaag cctatgaagt
    31621 ggtcaaactg ttggctaagg aaagtaaaga aaaaaacaag gccattatta tggtcactca
    31681 tgatgatcgg atgctaaaat attgtgacaa agtctatcgg atgcaagatg gagagttatg
    31741 tcaagagaga tagtagactg gtaagagttt atgatattag aaaaaaacca aacaagcaca
    31801 gcacttgttt ggtttttttc taagtgtgac tattatcaat acgtcaccat ttccctaaag
    31861 cttactatac gggatgctaa aggtatcacc atgctcaaag tcgccatatt ggtaacctcg
    31921 gtcaaaccaa cgttggcgtt gcttagaagt gccatgtgta aaactatcag gaacggttct
    31981 gccataggtt tcttcttgca gagtatcatc cccaactgcg tgagctgctg ccattgcttc
    32041 ctcaatatct cctttttcca aaaggccttg cccttgaaca taattagccc aggcaccagc
    32101 atagtaatca gattgtaatt ccaacttgac gttgagctga ttggctttag cctttgattt
    32161 tccttgtcta gcgctagcgt aattatccat aattcccaat tcattttgga tgtggtggcc
    32221 aacttcatga gcaatcacat aggccatagc aaaatcacct tttgcgccgt acttggttga
    32281 tagttcatta taaaaagaaa tatctaaata cactttttga tcgcctgggc aataaaaagg
    32341 accagaagag gcttgccccc tgccacaagc ggtttgagtt gctccagtat atagaactaa
    32401 tgttggttta tgataagtta accctttctc acgaaatgtc ttagtccaat agtcctcggt
    32461 agaggcgaag accttactga caaaagaaac ctgttcttga ctagccttgt caccatttgt
    32521 acgcgttact tggcttgatt gataggcatt gttgttggta gaagaaggct tgcctcctaa
    32581 aacaccagat aggccaccac ctcccataac taggagaagg agaagaataa ccagcttggt
    32641 tttccaacct cctcgtgaaa agagtaattg aagcaggaga ccgcccccta ggccgccgcc
    32701 cccaaaagaa ccagacgatt gaccacgtct atcttcaacc tgttgacttt ctctcaaatc
    32761 atccgttttc ataagtttct cccatctatt tcttgatttt attataaaat aattctatta
    32821 gaattgctat ttttat
//
LOCUS       DAUGJR010000019        32767 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUGJR010000019 DAUGJR010000000
VERSION     DAUGJR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32767
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.019"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(248..661)
                     /locus_tag="VH800_000903"
     CDS             complement(248..661)
                     /locus_tag="VH800_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8361982.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPNYQAPPKRVSEPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            complement(744..1493)
                     /locus_tag="VH800_000904"
     CDS             complement(744..1493)
                     /locus_tag="VH800_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEQ8361983.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            complement(1513..3999)
                     /gene="gyrA"
                     /locus_tag="VH800_000905"
     CDS             complement(1513..3999)
                     /gene="gyrA"
                     /locus_tag="VH800_000905"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEQ8361984.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELISTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIAEINTDRENSISKNKDN"
     gene            4190..5173
                     /locus_tag="VH800_000906"
     CDS             4190..5173
                     /locus_tag="VH800_000906"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEQ8361985.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            complement(5332..6702)
                     /locus_tag="VH800_000907"
     CDS             complement(5332..6702)
                     /locus_tag="VH800_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEQ8361986.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(6943..8670)
                     /locus_tag="VH800_000908"
     CDS             complement(6943..8670)
                     /locus_tag="VH800_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361987.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVIIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGIVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLVLDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            complement(8667..10391)
                     /locus_tag="VH800_000909"
     CDS             complement(8667..10391)
                     /locus_tag="VH800_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8361988.1"
                     /translation="MKRLRPYVKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGEQK"
     gene            complement(10401..11000)
                     /locus_tag="VH800_000910"
     CDS             complement(10401..11000)
                     /locus_tag="VH800_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEQ8361989.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAEHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            complement(11001..11978)
                     /locus_tag="VH800_000911"
     CDS             complement(11001..11978)
                     /locus_tag="VH800_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEQ8361990.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIEHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            complement(11985..13241)
                     /locus_tag="VH800_000912"
     CDS             complement(11985..13241)
                     /locus_tag="VH800_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEQ8361991.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDTDTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            complement(13231..13683)
                     /locus_tag="VH800_000913"
     CDS             complement(13231..13683)
                     /locus_tag="VH800_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8361992.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            complement(13701..14291)
                     /locus_tag="VH800_000914"
     CDS             complement(13701..14291)
                     /locus_tag="VH800_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEQ8361993.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            complement(14275..15114)
                     /gene="prmC"
                     /locus_tag="VH800_000915"
     CDS             complement(14275..15114)
                     /gene="prmC"
                     /locus_tag="VH800_000915"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEQ8361994.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISETFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRAVTDIFGKERMVVVDYG
                     VSS"
     gene            complement(15114..16193)
                     /gene="prfA"
                     /locus_tag="VH800_000916"
     CDS             complement(15114..16193)
                     /gene="prfA"
                     /locus_tag="VH800_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEQ8361995.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            complement(16228..16797)
                     /locus_tag="VH800_000917"
     CDS             complement(16228..16797)
                     /locus_tag="VH800_000917"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEQ8361996.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPDI"
     gene            16935..17120
                     /locus_tag="VH800_000918"
     CDS             16935..17120
                     /locus_tag="VH800_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEQ8361997.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            17173..18111
                     /locus_tag="VH800_000919"
     CDS             17173..18111
                     /locus_tag="VH800_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEQ8361998.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTSKGKQYHHILDRQTGYPIETDMLSLTIMAPSSFYCDIWTTRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(18175..19458)
                     /locus_tag="VH800_000920"
     CDS             complement(18175..19458)
                     /locus_tag="VH800_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEQ8361999.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(19458..20039)
                     /locus_tag="VH800_000921"
     CDS             complement(19458..20039)
                     /locus_tag="VH800_000921"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEQ8362000.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     regulatory      complement(20126..20221)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(20344..21327)
                     /gene="guaC"
                     /locus_tag="VH800_000922"
     CDS             complement(20344..21327)
                     /gene="guaC"
                     /locus_tag="VH800_000922"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEQ8362001.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHFESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     gene            complement(21605..23131)
                     /locus_tag="VH800_000923"
     CDS             complement(21605..23131)
                     /locus_tag="VH800_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEQ8362002.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            complement(23124..23852)
                     /locus_tag="VH800_000924"
     CDS             complement(23124..23852)
                     /locus_tag="VH800_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362003.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQTELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVVNLFGGDEHA"
     gene            24272..24961
                     /locus_tag="VH800_000925"
     CDS             24272..24961
                     /locus_tag="VH800_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEQ8362004.1"
                     /translation="MKNAISILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     QSNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHTFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            complement(25155..25927)
                     /locus_tag="VH800_000926"
                     /pseudo
     CDS             complement(25155..25927)
                     /locus_tag="VH800_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
     gene            complement(26054..27049)
                     /gene="pta"
                     /locus_tag="VH800_000927"
     CDS             complement(26054..27049)
                     /gene="pta"
                     /locus_tag="VH800_000927"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEQ8362005.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVEVRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIATGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            complement(27053..27958)
                     /locus_tag="VH800_000928"
     CDS             complement(27053..27958)
                     /locus_tag="VH800_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8362006.1"
                     /translation="MRFEFVADKRIKVKTLLKSYDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGMLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSCAIHLTDDFDSVIIGLQKKDRGY"
     gene            complement(27955..28791)
                     /locus_tag="VH800_000929"
     CDS             complement(27955..28791)
                     /locus_tag="VH800_000929"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEQ8362007.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            complement(28766..29437)
                     /locus_tag="VH800_000930"
     CDS             complement(28766..29437)
                     /locus_tag="VH800_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8362008.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            29525..30103
                     /locus_tag="VH800_000931"
     CDS             29525..30103
                     /locus_tag="VH800_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEQ8362009.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFVNSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHITFKYAKSKVARCINTLKKFNDK"
     gene            30243..31223
                     /locus_tag="VH800_000932"
     CDS             30243..31223
                     /locus_tag="VH800_000932"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8362010.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSNG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAADVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            31220..32347
                     /locus_tag="VH800_000933"
     CDS             31220..32347
                     /locus_tag="VH800_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8362011.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            32337..32684
                     /locus_tag="VH800_000934"
     CDS             32337..32684
                     /locus_tag="VH800_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEQ8362012.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAITDQSGLRLVNIFKTKDNQILQDKFYFLMD
                     SLVEREIFSKTVV"
BASE COUNT        10130 a         6765 c         5678 g        10194 t
ORIGIN      
        1 gtgacaacac agttattaac ttatattgtc attataacac tgtaagagtt tatcgtcaaa
       61 tattttgctt ttcctatagt tattctatta aaaaacttcg acaagattac tccaaaaatt
      121 gctcttcact ttgaaagtta accaaatcat ttaacgatca aaagagatta atcaagcaaa
      181 tgaagataca acaaataact atttttaacg agttttatag cacgatccag tcgttaacct
      241 aataagtcta ttcatgtaat tctaaaggca aaccatccgg atcaaaaaag aaagtcattt
      301 tctcacctgt gtaatcatca tgcctgatag gctccactgg aattcctaag ctctttagat
      361 catctacata actctcaatg ttggtaacac gaaatgcaag gtgcctcaaa ccacaggcct
      421 cacttttaaa ttctggttca cttacacgtt taggaggagc ttgatagttg gggtcacttg
      481 tcaccttacc aaaaatctcc aattcaatac gaccacaaga taaatctaat ttgtaatcat
      541 gcttgtcagg acgataattt tctctgataa tttcaaatcc gagtttattc acataaaaat
      601 cttttgacag atgataatca gatacaataa tagcaacgtg atgaatggca tttagtttca
      661 tcatatttct cctttcaaaa aaagtaggat gagataaatt ttctctatgg tcctactttt
      721 taaatattat atttaagata tatctaggta gatacttggt tataagaatg attaaaagct
      781 ttcaatacat cggcgggcgc tttatcaaaa tcgtattctg tttttagttc tcctttgaca
      841 ataatacgtt ctgttgcttc gatatctgta caagtcacta aagtcacttc tttgagacca
      901 gctgtatcat cgataacatc aacgcgttca ggagctaccg tgaaaacatc ttttatgatg
      961 tattcgtaaa ttttttcttt atctgttaaa tagatggaca tcccattttg tgctctttca
     1021 agcggcgaaa agagcatttg agatgaacct gtaattccaa aaatatgatg actggcaaga
     1081 gaataattat tttctcctcc cataacttgt tcttctttca tcgttcctgc gccataaata
     1141 agctcagtat ttcctaaacc tttaaaaatt ggtaaattaa tgccaagctc tggtatggca
     1201 atgcccccta taacaggaag ttgctgagcc gccatttgtg cttgcaagac actctctgta
     1261 ctaactggct ctacggcttg gaaatcaaat gttgacttag cctctttatt ctttttgatt
     1321 tgttttttcg aaactttcgt tacttgatat ttattagagt ttcgagcaat taatgtattt
     1381 cggataggtt tgttaaaaag caatgctaaa cctagaatta aaagtacagc tattagtagt
     1441 tttcttgccc aagacatgga ttttattttt cgacgctttt gtttttttac cattttttac
     1501 tccttattat gattaattat ctttattttt tgaaatacta ttttcacgat cagtattgat
     1561 ttcagcgata ctactgtctt caggctgaac caaggtaaat gttacaatct tagcatcagc
     1621 atctagtttc ataattttaa cacccaaagt agcacgacct gtttgcgaaa tatttgcaac
     1681 atttgtgcga ataatgacac ctttatttgt aatcaccatg atatcttctg taccatctac
     1741 ggtaaccaat ccagccaatt gaccattttt aggggtaata ttagctgttt ttattccttt
     1801 tcccccccta ccttttgtag gatagtctgt agcacttgtt ctcttaccaa agccattttc
     1861 ggtaattaca agaacttctt ggttatcttg aatacgtgac gcgccaacaa cgcgatcatc
     1921 ttcacgaagc ttaaccccgc gaacacccgt agctgatcgg cccatgttgc ggatgcttgc
     1981 ttcattaaaa cgaacagaat atccggaatg agttccaatg ataatgtcat cctgaccgct
     2041 tgtcaaaagg acgttaatca gctgatctcc ctctttcaac ttaagagcac ggagaccgtt
     2101 ttgacggata ttattaaatt ctgaaacttc tgtacgtttg acaatgcctt gtttcgttgt
     2161 aaagaagaag gatttacctg ctgtttcttc cttacgtgcg ttgataatag tttgaatggt
     2221 ttcaccatct tctaatttca atagattaac aattggaaga ccttttgctg tacgaccata
     2281 ttctggaatt tcgtaagctt tcaaccgata gacacgccca aaattcgtaa agaagagcaa
     2341 agtatcatgg gtacttgttg atatcaattc acgtacaaag tcgtcattgt tgactccagt
     2401 tccttggacg ccacgtccac cacgcttctg ggcacgaaat tcatcttgag caagacgctt
     2461 gatataacct ttatttgaca aggtaatcaa aacatcttct tcttcaatta gatcttcatc
     2521 ttctagagaa aggacttcac cgaccattaa ttctgtacgg cgtgggttag cgtatttacg
     2581 cttgatctca tccatttctt ctttgatgat agtgataata cgttctggtt tggctaaaat
     2641 atcagataag tcagcaatca aggccaacaa atcatcatat tctgattgaa tcttatcacg
     2701 ttccaaacca gtcaaacgac gcaaacgcat atccaaaata gcttggcttt ggcgttcaga
     2761 caagtcgaaa cgtgacatca attctgtctg agcaatgaca tctgtctcgc tgttacgaat
     2821 aatagcaatc acttcgtcta aatgatcaag ggcaatcagt aagccttcta aaatatgagc
     2881 tctggcttca gctttatctt tatcaaatcg ggtgcgacgt ataataactt ctttttgatg
     2941 actaatgtaa ttatcaatga tttgtctgag tgacaatatt ttaggcacac cattttcaat
     3001 agccaacata ttaaaactga aattcgtctg aagacttgtt aatttaaaga ggttatttaa
     3061 gataactgtc gcggatgcct ctcgacgaat ctcgataaca aaacgcactc cttcacggct
     3121 agattcgtca cgaactgctg taataccttc tagtcttttt tcttgtgcta aacgaacaat
     3181 gtgttcatgc actttcgttt tattgacgcc atagggaaat tcagtaacca caatacgttc
     3241 ccgacctgtt tgagttgttt caatttctgt tcgagagcgt aaaacgatag aacctttacc
     3301 agtatcataa gccctatgaa tacctgagcg ccccataaca agggcaccag tcggaaagtc
     3361 aggtccaggg atcacttcca tcaactctct tgttgtacag tctggatgtt ccattaccat
     3421 cttgacagca tcaatagact ctgccaaatt atgaggcgga atgttagttg ccatcccaac
     3481 ggcaatccct gtcgctccat tgactaataa attaggaaag cgagctggta atactactgg
     3541 ttctctttcg cttccatcgt agttatcttg aaaattaacg gtatttttat tgatatccct
     3601 taataattca agcgcaattt tactcatgcg cgcttcagta taacgttgag cggcagcacc
     3661 atcaccatcc atagaaccaa aattgccatg cccatcaaca agcatatggc gataactcca
     3721 ccactgagcc atacgaacca tagcttcata aatagaagaa tccccatgcg ggtgatattt
     3781 acccatgaca tcacccgtaa tacgagcaga ttttttatgc ggtttatcag gtgtcacacc
     3841 gagttcattc atcccataga gaatacgacg atgcacaggt ttcagaccat cacgcacatc
     3901 tggcaaagct cttgccacaa tgacactcat ggcatagtca atgaaactcg ttttcatttc
     3961 acttgtcaga ttgacgtcaa ttaaatttcg atcttgcatt taaggaatgc tccttttcta
     4021 gtcaatacta gatttcatta taccataaat tccttatttt ttcttattgg aagcgttatc
     4081 agtaaactat tttcattatt tttctgaatt caatgacaaa caattatcaa tatgttaaaa
     4141 taagaccgta tgagcttttg ctctaataaa attaaggaga tgtttagaaa tgactgcaac
     4201 taaacaacac aaaaaagtaa tcttggtcgg tgatggtgcc gtcggttcat catacgcttt
     4261 tgcattggta acacaaaata ttgctcaaga acttggtatt attgatattt ttaaagaaaa
     4321 aactcaagga gatgcagaag atttaagcca cgctctagct tttacatcac ctaaaaaaat
     4381 ctatgcagct gactactcag actgtcatga tgctgatctt gttgtcttaa cagctggtgc
     4441 tcctcaaaaa ccaggtgaaa cacgccttga ccttgttgaa aaaaaccttc gtatcaataa
     4501 agaggttgtt acacaaatcg ttgcatctgg tttcaaagga atctttcttg ttgctgctaa
     4561 cccagttgac gttttgactt actcaacatg gaaattctca ggtttcccta aagagcgtgt
     4621 cattggttca ggtacatctc tagattcagc ccgtttccgt caagctctgg ctgctaaaat
     4681 cggtgttgat gcgcgttcgg ttcacgctta catcatggga gaacacggtg actctgaatt
     4741 tgctgtttgg tcacacgcta acgttgctgg tgtaggtctt tacgactggc tccaagctaa
     4801 tcgtgacatt gatgagcaag gcctagttga tcttttcatt tctgtacgtg atgctgctta
     4861 ctcaatcatc aataaaaaag gtgctacttt ctacggtatt gcagttgccc tagctcgtat
     4921 tacaaaagct attcttgatg atgaaaatgc tgttcttccg ctttctgttt tccaagaagg
     4981 ccaatacgaa ggtgttgaag attgctatat tggtcaacca gctatcgttg gagcgtatgg
     5041 aattgttcgt ccagtaaaca ttccacttaa cgatgctgaa ttacaaaaaa tgcaagcctc
     5101 tgcaaatcaa ttgaaagcta tcattgatga agcctttgct aaggaagaat ttgcttctgc
     5161 tgctaaaaac taatcacaaa agagacttcg gtctcttttt gttttgcctg atattccttt
     5221 tccaacgtgc tataagagga taatcataag tttagaactt ttcaggttgc aacaattaaa
     5281 aagcaaaaaa gccagtgctg ctgaactgct ctggcttttt cctatcagat actagtcttt
     5341 ggcaccaagt gctgccattg tgatgtagtt gtaaggtttg ttgaaatgtg gtaagaagaa
     5401 aatatcagtt aatgccaact tttcaatggt tacgccttct tggatagcaa gtgagaacat
     5461 gtgaattccc attgacacat cttcacgggc tgccatttga gcacccaaga tacgacgtga
     5521 gtctttatcg taaacaatct taatggttac tgggaagtta ccgtgttcga taaattcagg
     5581 tttttggtta tcagtatact cagtcactgc agcatcaaaa ccaagacgtt ttgctttttc
     5641 aagtgtcaaa ccagttgaaa ccatgtgcaa tccgtaaatg gaaataccgt ttgagccttg
     5701 aacgccaata ccttcaaggt ctgtaccaca agcgttatgt gctgctacaa ttcctgtacg
     5761 gacggcattt gaagctaaag caatgtagtt tgtatcgcga gtagcattat cgtagatagt
     5821 tgcacagtca ccgatagcat aaacacctgg aatagaagtt tcttggcgtt tattgacaag
     5881 gaaagcacca ttacggaaaa gatcaatctt accatttcca agagttgtgt ttggacggaa
     5941 accaacggcg aggataacca tatccacatc gtactcattt ttgtcagtaa tgatcttttc
     6001 aaccttacca ttaccagcta cttctttaac tgtttcacca aaggctagtt gaataccatg
     6061 ttcttccatg tttttagcca ttaagtcagt caaatcacgg tcgtaataac ctgccaagca
     6121 agtgtccacg acatcaatca gaaccacttc tttgcctttg cgttggaaag cttcagctaa
     6181 ctcaacacca atgtaaccag caccaactac ggctacacgt ttaatgtctt tgttttcaag
     6241 ctttgcaatc acatcagctg agttttggta taacttcaca aattgaagat tttcaagagt
     6301 tgcttcaaat tcaagtgatc cttctttgat ttcggcacct ttaatcggtg gtaagatagg
     6361 ttgtgagcca gttgcaaaaa tcaacttgtc gtaagtttcc acgtggtttt taccatcaac
     6421 aagcgctgtc actgttttgg catcgtagtc gattgattga acaggtgatt ccatgtaaac
     6481 tttagcccct aaagactcta attcttcttt atctgaatag aaaagtcctt ctggtccagc
     6541 aatttgctca ccaatccaaa gtgccatacc acagcctaaa aatgaaatat ttgagttttg
     6601 gtcaaataca acaatctcat tagcatcacc gtagtttgtt aacatagtct tgatacaggc
     6661 cgtaccagca tggtttgcac caacaacaac gattttactc atatattttg ttcctcattt
     6721 cacaatatta tatagggctc tattatacca cagtcaaaaa acgcttccaa atatattgct
     6781 cacttttttg agttatttct tctttagtca actgtttttt ctcacttata aaaaaagatc
     6841 gtccgctttt tcgctgttat ttttttatat aacagcttaa agtttgttaa ttaactaact
     6901 ttaggaaggc ttaaaaagtt aacctttgtt aaaagacgaa ctttattcta tcttttgtaa
     6961 tctagcataa cagccgtttt ttgacattaa gctggcatgt gttccccact caaccaatcg
     7021 accttgatcc ataacaagaa tcaaatcagc tgattgaatc gttgataaac gatgggcaat
     7081 gataaagctg gtccttcctc tcatgagttc ttttagtgcc tcttgaataa cagcttctgt
     7141 tctaatatca atagaggagg tggcttcatc tagaaccaag acttttggtt ttttcaaaaa
     7201 cattctggca atagctaata actggagctg cccttgggac aaagcatcat cagaagcact
     7261 taagtaagta tcataagtct taggaagttg cataataaag aagtgtgcat gagctgcttt
     7321 ggctgctgcc actacttcat cacggctagc ctcttcactg ccgtaagcaa tcaactcatg
     7381 aacagtcgca tctttcaacc aggtttcttg caatactatg ccagtaatgg acctaagttc
     7441 ttccttagca taacacttaa taggaacttt atctaacttg atgctaccag catcaagttc
     7501 ataaaagcgc atgagtaaat tgattaaagt tgatttacct gcacctgtag gccctacaat
     7561 cgctaccttg gaacccgcag gaacagaaaa attaatatct ttcagtaagg gcctgtcttt
     7621 ttgataagaa aaacttactt cttcaaagtc aatttgcccc ttaaccgctg atgccttaaa
     7681 tgttagaaag tgctcttgct cttttatttc aatatctaaa aggtcataaa gcctttgcgc
     7741 acaagctaaa gaactctgta tctctgccaa gacagatgaa atatcgttga aaggtttggt
     7801 atattggaca acaacattta aaaaagtggt tagctgacct actgaaaaaa gtccagccat
     7861 gatacgaaca gcccctaaac ctgccagtaa agcataaatg acactattaa taaagcgagt
     7921 ggctggattg actgttgagg cgtaaaaaat ggctttttgt gaagcctcgc aataggtttt
     7981 atttaaaaca tgataatcac agatagactg ctcttgagca ttaaacagtt gaaccaaacc
     8041 ttcttgacga aggatttctt cagtaaactg agctaaattt cctctgcttt tggtctgtgc
     8101 ttgtgcataa tgaaaactct tttgagcaat aaaacgagct aaaaagaggg agcttggtgt
     8161 taacaccaaa accaagatta acatgagcca gtcaatctgt gccatagcta taatggtaca
     8221 cagaatcgtc aatagtccaa gtataaactg gttaaaaacc atttgtagac cattgatcag
     8281 ttgctcagtg tcggttatca ctcgactaac caaatctcca atggtttgac gatctagata
     8341 tgcaaaagga agacgatgaa ttttttccaa aagcttatct ttcaattgct ggctatattg
     8401 atatagcaaa cgactataga caagaggcat cacccattga atcaatgtgt tgaccacaat
     8461 aataactaac atttgcccca acagccattt taaagtttgc caagaattga ctgacaaact
     8521 catatcaacg gctttaccga taagaacagg caagtaaaca cttaaaccaa cttgtacaaa
     8581 actagcgatc acgagaatac aaacaggtag aggttttttt aacaaatcct gaagcactcg
     8641 ctttaggagg tgatgatctg ttttaatcat ttttgctccc ccttcacgta aagcgctagc
     8701 atttcttgat aaagtgcatt gcttactttt aactggtcat gactggcaaa atccaattga
     8761 tggccctgtt ccaacactaa aatcttatca gcaaactgca aattcttaat agattgcgtg
     8821 actagaatca ctaaaacatc tgataactct tcttttagag ctttaaaaag tcgtcctcga
     8881 gtctcattgt ctaaggcgga actggcatca tccaaaatca aaatgggttt tggcttcaga
     8941 agtgctctgg caatagctag acgttgccgt tgccctcctg aaaaatgacg gccgaaggct
     9001 tcaacaggtg cctctaattg ttctggtaag gcagcgacaa actcttttgc ttgagccaat
     9061 tcaagagccc gccacagttc ctcatcacta ataggcattg attgtcccag taggaggtta
     9121 cttctaatcg ttcctttaaa taattgagct ttttgaggaa caagagcaat cacatttcgc
     9181 cactcggtta gtgtttttgg cacttctcct tgccaattaa gactaatctc accactatat
     9241 tgtgaataag tttggcagat caagtcaatc aaagtcgttt tgcctgctcc agtaccacca
     9301 atgatgccaa tccattctcc ctgatcagca cttaactgaa tatcatacag acttggctct
     9361 gctgctcctg gataagtaaa ggtcaagtgc cggatggtca acagatgagt tgaaatagga
     9421 ccatctttaa gtaagggcaa aggcgcttca tcagctaaaa caaacacctg attaatccgt
     9481 tttgcggctg ttacactttg attgatggtt cccatcaaca tggtcatttt caaaagttct
     9541 gccaaaatct gcaagaggta attaattaaa gcaaccaaca tgccctgact aagcgatcta
     9601 tgagctactt gccaacttcc ttgccaaatc aagattaaca gggtaagatt gaccactaaa
     9661 aaagtcatag gattcaagac attggctagg gtagcagctt gatattggtg gcgacttaag
     9721 agcatatttt gctgcttaaa tgcttggagt tctttttggg tttgattaaa agccttaatt
     9781 actcggattc cttgtaactg ttggctagtc aaacgaacca agtgatctgt ttctcggcgg
     9841 attaagagat aaaggggacc taataaatgt gacataacaa aaacaagtgt tagtaagaca
     9901 atcaccatca tcacaaacca tagggttaga cttggactaa tccaataagc cattaccata
     9961 gcaccacata cgataatagg ggcccttaga aaaagacgca aaaattgatt gataccagtt
    10021 tgaatttgaa aactatcact ggtcaatcgt gataacagac tagcataacc aagatggtct
    10081 tggtcctcct tgctcaaaaa catgattttt ttaaacaagt catctgtcat ttgtcttgta
    10141 aaaccaacag ctgctttcga agaaaaatac tgggctgtaa cggaaagcaa taagccaatg
    10201 gttgctaaac caaataatgt taaaacaacc ctcaaaattc cctggctgtt gtgttgacta
    10261 atcgatatat caatcatgtt agcaattaac aaagggacta ataattcaaa taaagcttct
    10321 aataatttaa aaagaggacc taagatactt tcttttaggt accctttcac atatggacgt
    10381 aatcgtttca tgataacttt ctaaaaaagg ctcatcagtt caattaaata aagattgaaa
    10441 tgaacttctc gtgagtaata gatattgccg ccattcttat aaagcttacc tccagaaatc
    10501 aaggcgaggg ggtggtaata aaaataggtt tgaccactag tgttgcctag gcttggcgcc
    10561 acaacggttt tggaataggt agtcgctaaa tcaacggtat tttgacctcc atgttcagca
    10621 atataatcaa tataagctgt tccaaaatta taggcctgaa cagccgtcca agaatctact
    10681 cctgcttcct cagctagagc aagattatga gacagtaaat tcaccccgtg ctcaatactg
    10741 gcctgactat ctgtaatcga gtttttttgt cctgaactgc tttcactgga ttgcatgaca
    10801 tctgcttctc ctccttttgt ctcggtgtat atcatagcta agactaagtc tacatttgcc
    10861 tttgtatcat tttctgctaa tgttttctca accataggct tatatgccaa aacacgttga
    10921 acattgtgat gaataacaaa ggattgataa atgacaaaaa gaagaagaaa actgcaggca
    10981 cgctttaaaa gtctaaacat ctatttggtt ttaatatcct ctatattttt aatcaagatt
    11041 gaataagtcc catcatcatt taacaaaaat tcaaccgctt cagcatcctg ataaatggca
    11101 tttggtactg ttaattctat cccgtttgat aacgatagct tttgattttc tagttttttt
    11161 atctgtctag aatgttcaat atcgctaatt tttataggtt ctggaatgac atctttgact
    11221 tgatccacaa aggttaaacg ggctgttaaa ttatcatcaa agagttggtc agctaatttt
    11281 tctggtgata aaacgtcgtc tgcttctaac tgcttaaaaa gagtggattt catctttgac
    11341 tgaaaagtaa aatcatcttg attaaaatgc tctgcaattt tttgagcggt ttgttctatc
    11401 attttgatag actttttaac agattgctca ggtgtaactt tcaagaggtg ttctgaaaaa
    11461 taattagcaa aactgccatt atgcttcaca cgcttttcaa tcaagtagta ctgaccagat
    11521 ttgagattaa tgactagtgc ttcatctggt gtctgggtgg gactcggcag attattctgc
    11581 gtcaccgtaa atggatgttc ataattgtca gaaaggtgag caaactgttc tttcaaagca
    11641 attcgcaaga aagcaaaaaa gggttcgcca tccttatcaa actgaacaaa gactaagtca
    11701 ttggtttttt gatcctctga aataacaaag gcttccttcc ataactgggc aatggtaaca
    11761 gacgtttcca acaaatcatc accaatggtt gtaaaaaagg tattattagc ctcaaactga
    11821 ccacgtttgg cttcgtccga gaacactttg gccaattttt ttcggaaata ttcatcaatt
    11881 cgcggtgtaa tgctcactaa acgatctgat aacagtaact cagtgtcatt gggagaaaat
    11941 tgatgaatga caatacgttt tatataacta tctaacatga ttccttactt tttatagagt
    12001 gggaaggcat cggttaactg acgcacttcc tgacggactt cttcaagaat agtttcttga
    12061 tcatgattaa ccaaggcttt gatgataaga cgggcaatgg tctgactctc tttaacaccc
    12121 ataccacggc tggttatggc agcacaacca atgcgaatac ctgaggtttt aaatggcgac
    12181 aaggtttcaa aaggaatggc atttttatta agggtaatat taacctcatc cagaagattt
    12241 tgcgctagtt taccattagc aataacctta gtgacatcta ctaaaaagac atgattatct
    12301 gtaccacctg agatcagacg gaaacgatca tcttgtgcaa aaactgctgc catagccgca
    12361 gtattatcaa taatagcttg tgcatagtct ttaaaggctg gatccaaggc ttctttgaag
    12421 gcaaccgctt tggcagcaat cacgtgttcc agaggtcctc cttgtaaacc agggaaaacg
    12481 gccgaattaa tctttttagc aagagcttcg tcattggtta atatcaagcc tccacgagga
    12541 ccacgtaagg ttttatgggt tgttgatgtc acaatatgcg cataagggac aggactcggg
    12601 tgcacacctg ctgctacaag gccagcgatg tgagccatgt ccaccattaa gtaagcacct
    12661 acgtgatcag caatggcacg aaacttttca aaatcaatgc ttctagagta ggccgaagcc
    12721 cctgcaacga taagctttgg ttggaccgcc tttgcttgtt ctaaaatcgc ctcataattt
    12781 aacatttcag tatcagtatc tactgagtaa cccacaaaat ggtaggtttt tccagaaaaa
    12841 tttactggag agccatgcgt gagatgacca cctgcagcca aatccattcc taatacggtg
    12901 tcaccagcct caatcaaggc catataagct gctgcattgg cttgacttcc ggaatgggct
    12961 tgaacattgg caaatgcggc accgaaaagt ttcttagcac gttcaatagc aagcgtttcg
    13021 acaatatcca cacattctgt tccaccataa tagcgattac ctggatagcc ttctgcatac
    13081 ttattggtta aaacagaacc ttgagctgcc atgacagctt ttgaaaccat gttttcagat
    13141 gcaatcaatt cgatatgatg ttcttgtctt tcttcttcag catgaatggc atcccaaagc
    13201 tctttatcaa agtcttcaac attaccttta tcaaaaatca ttgtcatctc cttgtaagtt
    13261 tttgatgaat cgtaattgtg ttttatcatc tgcatagtcg aggtttcggt aaaaagcatg
    13321 cgcttcttta cgatgactgg cagaattgag gcgaataaag gcaatgcctt cctgcctagc
    13381 ttgggattcc agggccctta gtaaggcact cccaattccc cttctctgat aggctggtaa
    13441 aacagccaag cccaagagat taagaccatc agaagcataa agggtttcat accgttcagc
    13501 gtgaacatag cctaataatt gattggtatc cttgtcggca taagctaaaa aatagtgatg
    13561 gcaatcctca atcaatcgtt catattgcct ttctaacaag tcaagcgaaa ctaaatagcc
    13621 aagggctttg gcattaattt cttgtagcat aggacagtcc gttttactta atggtctcaa
    13681 cattccaagc ggctcctctc ttaaaagcga agttcaggca cgttagctaa taattcttct
    13741 ttggtgatag caccttgacg taaaatcaca gcacgctcac ctgataagtc taagatggtt
    13801 gaatccttac ctgttagaaa aggatcatct gcataaccaa acacttgaaa gtcaaaatct
    13861 tgcataatat gatcaaaaac tcgaccacta gctttgccag ataagtttgc agaaggacca
    13921 attaaagggc ctgttttttg aattaaagct gcggtaattg gatgactggg taagcgaaaa
    13981 ccaaccgttg aaagtcccga attaatccaa taaggaacct ggtcattagc ttttaaaata
    14041 atcgttaacg gacctggtaa aaaggcttgg tataatttct tgaggtatct cggctgttct
    14101 tttgaaaagg ctaagatact attaaaatca gccacattaa ggttcattgc tttatctcgg
    14161 ggtctttgtt ttaagtcata aacagcattt actgcttttt catctaaagc cttggcaaaa
    14221 agaccataaa ccgtttctgt tggtaaaaca agggcatcac ctgattcaat gatactagct
    14281 agatactcca taatcaacaa ccaccatcct ttctttgcca aatatatccg ttacggctcg
    14341 tatatgtctt tgaggaaaat aggcttgtaa catatctttt ataccttcag cttgcttata
    14401 accaatttca aagtaaagct tcccctcctt agttaagtaa ttgtcagctt gttcaataat
    14461 cttacggtaa atagcatagc cattttcttt agcaaaaagt gccaaatgag gctctgattg
    14521 caaaacattt agactgactt cttccttatc ctcgtaggat atgtagggag gatttgacac
    14581 aataatatca aatgtttctg aaatgagact aaaaacatct gattcaataa acgttatatc
    14641 aagctggtaa gcatcagcat tggcttttgc caagtcaaga gcagctctag aaatatcaga
    14701 tgccgttact tgccagttag gcctttcttt tttgagagaa atagcaatcg ctccactacc
    14761 tgtaccaata tctaaaacat tcaacggtgc atcaagattt tcagctaaaa tcatgtcaac
    14821 taattcttct gtttctggcc ttggaattaa tacacgcttg tcgactgcaa gcttcaaatc
    14881 acgaaaataa gcattacctg taatatattg aggagataaa tgctgactta gagaacagaa
    14941 aatatgttcc aaaagaacag catcttcagg agtcacagct tgattttggt gaatcaacat
    15001 atctagactt gaccattctt tgatttctct aaaaacatag gcgagatttt cgcgatcctc
    15061 atctatttgt tctagtttat cttcataagt tctgattaat gtagcatagt tcattagtta
    15121 ttgagagatt ctaatttctt tgtctgatca tacataacga gtgcatcaat aacttcatcc
    15181 atttttccag ataaaatagt atctaatttt tgaagtgtca aaccaatacg atgatctgtt
    15241 acacgatttt gcgggaaatt ataagtacga atacgttctg aacgatcacc agtaccaact
    15301 gttgatttac gttcagcatc ttgttcatct tgagcaattt gcgcaaaatg gtcagcaaca
    15361 cgagcacgaa tgattttcat cgctttatca cggttttttt gctgagtacg ctcttcttgc
    15421 atttcaactt tgattcctgt aggaatgtgt accatacgaa ctgcagtagc aactttattg
    15481 acattctgac caccagcacc agacgcgtgg taaatatcga cgcgaaggtc tttaggatca
    15541 atgtcgtatt ctacttcttc aacttctggc attaccaaaa cagttgcagt tgaagtatga
    15601 acacgaccct gactctctgt cactgggaca cgttgaacac gatgagctcc tgattcatat
    15661 ttaagcttag aataaactga ctgaccagaa accatggcaa ccacttcttt aataccacca
    15721 acaccattaa cggatgattc cataacttca aaacgccatc cttgagtttc agcatatttt
    15781 tgatacattg ttaaaagatc accagcaaaa agcgctgctt catcgccacc agcagcacca
    15841 cgaatttcta aaataatgtt tttatcatcg ttaggatctt taggtaatag aaggattttt
    15901 aatttttctt catactcttc tttagctgct tttgattctt taagttcttc tttagccatt
    15961 tcttctaatt caggatcacc actggcatct ttgatcattt cttcagcatc tgaaatggtt
    16021 tgaatgactt gcttatattc tctataagct gtgacagttt ctcgagtatt agcttcttca
    16081 cgtgataatt ccataaatcg ctttgtatct gagacaacat ctggatcact aagtaactca
    16141 cctaactctt cataacgatc ttcaactgcc tgcaattgat cataaatatt catttttctt
    16201 tgtatctcct ttaaaaccga ttacctttta aatatctgga ttaaaataat gttttcgaca
    16261 aactgggata tatgtttcat taccaccaat ttgtatctga tcaccttcat agacaggttt
    16321 tccgttttct gtccttaaaa ccatggttgc tttcttacta cagtattggc aaattgtttt
    16381 gatttcatca atcttatcgg ccaataatag caaatgtttt gaaccttcaa aaagattgtt
    16441 ttggaaatca tttttcaaac caaaagccat gacaggaaca tttagctcat ccaccacacg
    16501 cgccaaatca taaacatttt gcttgcttaa aaattggctt tcgtcaatca ggacacaata
    16561 aggtttttcc tccaattggg caataaatgt gaaaatatcc atgtcatttg aaatggggat
    16621 agcttctcgt cgcataccaa tacggcttga gacgatgcca aaaccatcac gtgtatcaag
    16681 agcacttgtc ataatgacaa caggtttgcc ttgttcttca tagttatgag caacttttaa
    16741 aatttcaatg gttttaccag aattcattgt cccatattta taatagagtt gagccaaagc
    16801 ggaaaatcct actttctata gtattctacc tattttacca caaaggctga agttttccca
    16861 gccattgaaa acagtgtata ctttttcaca gcattatgtt acaatgatgc ccaataacat
    16921 aaaggagtaa cattatgcca tttgtaacaa ttgacttgtt tgagggacgc tcacaagaac
    16981 aaaaaaatca attagctcgc gaggttaccg aagtagtctc acgcattgca aaagcaccta
    17041 aagaaaatat ccatgttttt atcaacgata tgcctgaagg aacttactat cctcaaggcg
    17101 aaatgaaaca aaaatcataa tgaccttccc ccactcctta gtgggggtat tctgctaaaa
    17161 agaggactaa ttatgtttgt tacgcaacaa ttaaagctaa tgggaacagt tattgatatt
    17221 cagatcgaat ctgacaaagc ttgccaacaa ctaagtagag tcattgactt attatatact
    17281 tacaaaaatc gtttttcagc taatgattca aactctgaat tgatggctat taatcaggcg
    17341 gctggtgtta aacccgtcag cgttcactct gatttattta acctaatcca aattggtaaa
    17401 gctcatagct tgtcaacacc aagtaatctt aatatcgcca ttgggccact tgttcaagcc
    17461 tggcgaattg gatttgaaga tgctagagtg cctagtcata accttatctc acaacagtta
    17521 gctctaacag atcctagaca ggttcttata gatgacaaaa aacagactgt ctttttacaa
    17581 caagtaggaa tggctttaga cttaggagcc ttagcaaaag gttatattac tgataagatt
    17641 atggcctacc tgattgaaga tggtattgac tctgccctta ttaatttagg tggaaatgta
    17701 cgcgttcatg gacctaatcc gaaaagccct gacaagactt ttcgaattgg cattcaaaaa
    17761 ccagatgcta aacgtgggca acatcttggt gtcatcaagg ttaacaatca ctctgttgtg
    17821 acttctggaa tttatgaaag gcagtttaca tccaaaggga aacagtatca tcatatctta
    17881 gatcgtcaga caggctaccc tatagaaaca gatatgctta gcttaacgat catggctcct
    17941 tcttcttttt attgtgacat atggactacc cgtttatttg gtcttgatag ctcaatgatt
    18001 atcacacttt taaatacctt tgataatatt gaaggtcttc tagtaacaag aaagcaccat
    18061 gtccttatgt caaatggttt gagacactat tttcaaccat actatcatta aaaggggtta
    18121 acggtttgct caaaactgat cacagaaaaa acggctcaat tagccgtttt ttaattattc
    18181 atcttgtttg tctttgccat ttaaaactaa atttaagaca acagaggtca aagtggcaat
    18241 cacaatacca ttcgttaaga acatttgagc tgtctctggt aagctggcaa aaagattagt
    18301 gccattaaag cctaaacctg ctgagatgga aacggcagca ataataaaat tatactcgtt
    18361 cttttggaaa tcaacacgat taagcatttg cattccttga agagcaacca taccaaagag
    18421 aacaagcatg gctccaccaa gaactgggct tggaatcatt tgtgccattg ctccaaattt
    18481 agggagtagg ccaatgacca caaggatacc tgctgcgtag taaatcggac gacgggtttt
    18541 aatacctgag atttggacaa gtccaacgtt ttgagaaaaa ccagtgtaag ggaaggtgtt
    18601 aaataaccca ccgagaaaga ctgcgatccc ttctgagcga taaccattgc gcaaacgttt
    18661 ttcatctaat tgatcattag tcaaatctga aagcgctaag tagacacctg ttgattcaac
    18721 catagaaacc gttgcgatga tacacatcat cacaatagaa gtgatttcaa aagttggcat
    18781 gccaaaataa aatggggttg gcacatgaat ccaagaagcc tctacaacag gagttgtatc
    18841 tactaatccc atcatagctg aaaccaaagt tcccgctaca agcccaatca aaatggaaat
    18901 ggatttcaca aaacctttgg taaatttttg gactaaaaga ataatgacaa tcgtcaacaa
    18961 tgataacatc atgctttgtg ccgtaggctc tttgacgtta tctcccatat tccccatagc
    19021 aacacctacg agacttaagc caataacggt aatgaccgat cctgtaacaa ttggtgggaa
    19081 gaaacgagca atcttagaaa aaatacctgc cactaaaatg acataaattc ctgacgcaat
    19141 gagggctcca aacatggcac ctgaaccttg ttgcgctcca ataatggata gaggtgccac
    19201 tgattgaaaa gcacatccta aaacaactgg taatcccact cccgtatgct tggttaactt
    19261 taactgtaag aaagtagcca caccacacat gaaaatatct gtcgaaatca ggtaggtcaa
    19321 ctctctagcg gaataaccta aagcacctgc gatcataatt ggtactaaaa tagatccggc
    19381 atacatcgaa agcacatgct gtaagccaag gacagctgat tgcgagtgag aatgttcctg
    19441 ctttgttgaa tgtgtcatta tgcgtcagcc tccaagaagt ttagattacc attttcaaag
    19501 tttttaatac gggctaatga ggtcacttca atgcccatat cttcaatcaa tcgacgacca
    19561 tcttggaaag atttctcaat cacaatacca acgccgacga cttgtgcccc tgcttgacca
    19621 ataatctcaa tcaagccttt ggctgcctga ccattagcta aaaagtcatc aataatcaaa
    19681 accttgtctt ctttagatag gaatttacca gcgatagaca ccgtgctcgt cacttgttta
    19741 gtgaaagaat aaacttctgc tgtcaaaatg ccttctgtca tggtaatgtt tttatgtttt
    19801 ttcgcaaaaa tcataggaac atccattgct tctgcagcgt atacggctgg tgcaatacct
    19861 gaagcttcga ttgtaaccac ttttgtaatg ccagcctcag catatttttg agcaaacact
    19921 ttaccaattg ctttcatcaa ccggtaatca acttgatgag ttaaaaaatt atctaccttt
    19981 agaatattct ctcctagaat attgccatct gttaagatgc gttcttcaag taactgcata
    20041 aatctccttt tgattcaaat agaaaaagcc tgccgcaaag ccagaaacta taagagtttc
    20101 tcactttgca aggttaaaaa ccaagcaagc ctaaaagctt acttattgtt agacattaag
    20161 gtgtcttgta gagacgctgc gccaattcac agcataaata agtatgtcat tattgaattc
    20221 attataataa tttactattt taccatgttt cttatttttt tcaataccta cagagatatg
    20281 ataaaagcat ctccagcatt aagctaaaaa attctttact ggtcctagct aactccatat
    20341 catttaaatg gaatcaccat tccaaataga atttttgacg ataacataat caacatgacg
    20401 caaactgtct aaatctttac cacccgcgta agaaatggac gattgcaaat cctgttgcat
    20461 ttcggtcagg gtatctgata agtgaccttt tgtaggcaat aagatttttt tgccttctac
    20521 atttttatgc tcgccttttt gatattctga cgccgagcca taatattctt taaacgtttc
    20581 accatccact tctaccgttt ttccaggact ttcaaaatgt cctgcaaaaa gcgatccaat
    20641 catgaccata ctagctccaa agcggatgga tttagcaata tcaccatgtg tgcgaatccc
    20701 accatcagca atgataggtt tacgagctgc ctttgcgcac cagcgcagtg ctgctagctg
    20761 ccaaccacct gtaccgaaac cggttttaac tttagtgata catactttgc ctggaccgat
    20821 gcctacttta gtagcatcag cacctgcatt ttcgagttct cgtacagctt ctggcgtacc
    20881 aacatttcca gcaatgacaa atgtttctgg taattcagtc ttgatatgct taatcatatc
    20941 aataacactg ttagcatgac catgagcaat atcaatggtg ataaactcag gagcatcctc
    21001 tttcaaagag gtcacaaatt catattcaca agctttaacc ccaacagaga ttgatgcaat
    21061 caagccttgt tcatgcatgc gtttgataaa aggtttgcgg ctatcttcat caaaacgatg
    21121 cataatataa aaataaccct cttttgccaa ctgctcagca attgtttcat caataatggt
    21181 ttgcatattt gctgggataa ctggtagctt gaactggtat tttccgagtg tcacacttgt
    21241 atctgcttgt gaacgactag taataatgca cttgttagga atcagttgaa tatcttcata
    21301 atcaaataca gggatgtcat taaacataag tttctcctct tttaacatag attaagaaaa
    21361 acaagttagt tctcaccttc ttctctaagt cctctataca aaataatctt cctatgacct
    21421 ctgatgatta gaggtatctt taggtaaaaa cttacctttc attttataga ttacttattt
    21481 gtttatgttt tgtcaaattt atatgctatt tttaatttta aagttcggtt tttgtgttta
    21541 tgaattgtta cttcttgaac ttaagagacg aaaaaatgcc agtcctacgg accaacattt
    21601 ctgtttattt ctggattaag cctgttttca acagataatc tcgagcgacc ttattagcat
    21661 ctgctccttt aacagatacc tcgtagttca tgtcctgcat ctctttttca gtaatttttc
    21721 ccgctaattg attaagaatg ccttttaatt ctggatgttt tgttaataag gaagttttca
    21781 tcaaaggagc tccctgataa ggtggaaaca actgtttatc atcctttaaa actttcaaat
    21841 ggtatttcgt aatttcagca tccgtagagt aagcatctgt tacttggata tctcctgatt
    21901 gaattgcttg ataacgaaga gctggctcca tcgtcgccac agatagctgt aatccatatt
    21961 gagattgcat tcccttatag ccatctgctc tgtccttaaa ttccaaagta aaaccggcct
    22021 ttaaagtatc agcatgcgct tttaaatcag aaatggtttc aatctgatat tccttagcca
    22081 atttttctgg catagcaaca gcatacgtat tttggtaagc aaatggcttg agaagggtca
    22141 gtttatcttg cttagcaatg ccttttttag catcctcata gacctgctta gggtcattag
    22201 acaaaggtgg tttgtcgcgt aaaagacttg atgttatggt tcctgtaaat tcaggataca
    22261 tatcaatatc tccagattta agggcttcat ataagaagct agttttccca aaattagatt
    22321 tcaactcaac acttatatct gattggtctt caattaattc cttatagaga ttaatcagaa
    22381 tatcgggctc tgctcccaat ttaccggcaa taaccactgt atcttttcct tttgaaaact
    22441 gactaagcgc cataggagta tacgatgcta gcagtgcaag taaggtaatt ccaaaactaa
    22501 tcataatccg tcgcaaggaa gctttctcaa ggtactgtaa caaactattg aaaataatag
    22561 ctagcagagc tgaagaaata gcccctatca gaatcaggtt agcattatta cgatcaatcc
    22621 ctaataagat gaaagagcca agtccaccgg ctcctatcaa ggaagctaaa gtagctgtgc
    22681 cgataatcat gactgctgac gtccgcacac ctgacataat aacaggcatg gcaattggaa
    22741 tctcaaatgt tttcaatcgc tcccatttgg tcatcccaaa agctattcct gcttccacga
    22801 gacttgggtc aataccattt aatcctgtga tggtgttttg taaaatcgga aaaatcgcat
    22861 agataactaa agctgtcact gcaggcaacg ttccaattcc cattaaaggg atgaaaagac
    22921 caagcaaagc cagtgaggga atggtttgaa aaacacctgt tacctgtaac ataatgtctg
    22981 accaacgttt gctgcgactg agaagggctg ctaaaggcac acctattagc aaggcgatca
    23041 taagagataa aagggaaatt tgcaggtgtt cccccagagc cgccagccat tcattaaaac
    23101 ggttttggaa agttacaaac aaactaggca tgctcatcac ctccaaataa attgaccaca
    23161 aaagcattag cagggtgggt cttaatcatt tctgggcgat ccagttgcac aatttctccc
    23221 tcatttaaaa tagctacgcg gtctcctaat ttaatggcct catcaatatc atgtgtcaca
    23281 aatacaatcg tcatgtcaaa ttccttgtga agactcaaca ttaactcttg caattgttta
    23341 cgtgaaatag gatctaaggc tgaaaatggt tcatccatca atagaatttt aggatgagaa
    23401 atgatagcac gtacaatacc aatacgttgc tgttcacctc ccgataaatc acttgggtaa
    23461 cgatcaagat aatctttagc aggtaggccc accttatcca ataattcttc agttttttgt
    23521 ctaatttctt cagctgacca ttgcttcatc tcagggataa tcgcaatatt ttcagctact
    23581 gtgagattgg ggaacagagc aatttgctgc aatacgtatc caatagatag cctcatctca
    23641 cgtaaatcta actctgtctg tgggacgtta tttagtaaaa tatctccaga gcttggttca
    23701 ataaggcaat taatcatttt taaaagtgtg gtcttgcccg atccgctggg gccaaccagc
    23761 acaaaaaatt cacgatcatt aatttgaaag gtctgctctt gcaaaacctt tgtctgacca
    23821 aaagttttag aaacattatt aaaacgtatc attatttctc caattcattg gttaaagtaa
    23881 cagcataaaa gctgatgagt tcattcaacc tgtctctctg tcattttttc tcaaaacgtt
    23941 ctgagtaact acaaggaatc actgcatgcc ctaccatttt tagacaaacg catctactaa
    24001 ttaaagggac tcttaggtat cctcagtaag gtagaaacta ccaattctca aaaacttttt
    24061 ctctcattat tttcttgtcg tttgttgttg accattataa aaagtttccc actataagtc
    24121 aaataatgag actattaccc ccttatagaa aaacaggtca ctgggtcagc ctatctctcc
    24181 aaaattacct tatcaaaaat cctagacttg cctatgatga tagataagca gattaattgt
    24241 cttttctaga aaatacagct atcatacaat tatgaaaaat gctatttcca ttttagcgct
    24301 cttaacacct gaaaaccaac ttgaagagac gtttattaga gagctttccc accacttctc
    24361 acaccttttt gaggtgacta ttctcactag caaagccaac attcagtcaa atcaattgtc
    24421 gactttccaa ggaattttca gtttccatga gcatgacatt gacttgccta cactctattt
    24481 caaaacttct caacatggtc agggcttttt agtgacagaa agtgtctttg atcaagcaac
    24541 agcagtctta tcgttaagcc aatacctcac tggattttac caaaaatttg atggacattt
    24601 tttacagtac cttcctttgc aagcaaggtt atctgatgca aatggaaaca tcatagtcga
    24661 taatcatact tttaatggaa gttttttgcc aactactgat aaagaaatag aagattggat
    24721 tcttgctgaa ttgcgtttat cagataaccc ttgtaaaacc ttcctacttc cttcgggttc
    24781 attggatcat atttacatgc agcattatca agctcttaaa aatcctcaag gtcagctggt
    24841 gggagttttg gataccgttc aagacattaa accgttatta aaccagtatt tagaagaaac
    24901 tggacaagcc attgttggct ggtccgatgt cacatcaggc ccttccattt tagatcacta
    24961 aacttgattt taaataggga gttcagccta aatcatcaac gcacaagaag caatcatgaa
    25021 cgcttgaaga cctcaaaacc ttcttcttga ctgctttttt tgatgactga atcggtaagt
    25081 ctcacttata aagaataagc catcccagta aaccattttt ctaaagatta ttattcttat
    25141 ggactcatcc cttgctagtc acgagtaact ggttgcggtc cataactttg cgacactggc
    25201 atcagctcaa tacgattaac attaacatga gggggctgat gaatcaccca tgatacggtc
    25261 gacgcaatat tttgaggttg aatggcatgt gctccttgat aaatggcctt cacccgttcc
    25321 tcatcaccat taaagcggac ctttgaaaat tctgtccctt tgaaaattct gtcccttcac
    25381 atagaccggg ttcaatattg gtcacacgta tatggctacc tgctaaatca gctcgtaaat
    25441 tgagtgagaa ctgcttaaca aaagccttgc tagccccata aatattagct cccggatagg
    25501 gaattgtccc tgcggttgac cctaaattaa taataatacc atcatctttg gagaccatat
    25561 gtggtaataa ttgacgtgtg agataaatca acccaacaat attggtatta atcatcgtca
    25621 tccaattctc aaaatcggct tcataagcct tatcaagtcc taatgccaag cctgcattat
    25681 tcactaaaat agtaatatct tgccactgat ttggtagact tgtcaaagca tcatcaatcg
    25741 ctttggtatc tgtgacatcc atctgcaaag ggtaaaagtt gtccgaccca aagctcgttt
    25801 ctaaggcctt gagtttctca agacgacgag aagcaccaat aacctttatc ccatctgcaa
    25861 ttaagtgttc gacaatggct ctgccaaaac cggctgaagc ccctgttact aaggcaatat
    25921 ttcccataca tttcctcacc ttcaaaaaaa acgagatggt ctggccaact cgtttttaat
    25981 aatgtcaatt agtcttagga caaattctaa cacatcactt agcagttaga atcctatatc
    26041 aaggggtctt gagttaccct tggctttcaa tagcttgtgc tgctgtaata atggctagtt
    26101 tgtaaatatc ttcagcgctt gagccacgag ataaatcatt aacaggtttg ttcaatcctt
    26161 gtaagattgg tccaatagca tcaaacattc ctaaacgttg tgcaattttg taaccaatat
    26221 ttccagactg caagtcaggg aaaacgaaag tattagcttg accagcaacc gctgaatctg
    26281 gtgctttgat agccgctgtt tcaggaacaa aggctgcatc aaattgcaac tcgccatcaa
    26341 gtgccaaatc agggttcaac cctgtagcaa tttctgttgc ttctcttacc ttatcaactt
    26401 gaggcgcttt accagaacct tttgttgaga agcttaacat agcaatttta ggatcaatat
    26461 caaagatttt agctgtttca gctgtgttaa cagcgatttc tgccaattct tgtgctgttg
    26521 ggtcgatatt gatagcacaa tcagcaaaca cgtaacgctc gctcgtattt tcgcggttca
    26581 tcaagaagac acctgaagtt cttgagatac ctggtttagt tttgatgatt tgaagagctg
    26641 gacgaacagt gtcagctgtt gaatgaatag cccctgatac cattccatct gctaatccca
    26701 ttttaaccaa cataacacca aagtaattaa catcacgaag cattttatct gcatcttcaa
    26761 gcgttgcttt tcctttacgg acctcaacaa aagcttcttt cattttgtca aaatccgcat
    26821 attcatttgg attaatgata gtatagtctt gatcagcgaa acctaatttt gtcaaaaggt
    26881 tgcgtacctc ttctgactgt ccaaggataa tcggttctaa gagtccttca aatttcaaac
    26941 gagcagctgc acggacgacg cgctcatcat taccttctgg gaaaacaatc ttcatgtttt
    27001 taccaagaat tttttctctt aaaccaccga ataaactacg aatactcatt ctttaataac
    27061 ctctatcttt tttctgtaaa cctatgataa cgctatcaaa gtcatctgtc aagtgtattg
    27121 cacagctaca atcactttct gtaaatggat ctttgaaatt caaataatga caatgtaaag
    27181 cttgccttgt tattcctaag tccaaacgac ctccgtaaag gtcatcccct aaaagtggaa
    27241 aaccaatatg ggcaaaatga actctgattt gatgggtacg tcctgtatgc aatttgatat
    27301 ccactaaatg cacattttct gaatagcgcg ccacaacctt atagctagtc ttggcatatt
    27361 tgcccatagg gtcaactgcc ctggtaataa tactatcttt tgaacgccca attggagcaa
    27421 taatatctcc ttcatctggc aacatcccat ttccagaaac cagagcaaaa taacgtttct
    27481 ctattgagcg agtttggagt tgcttgtcca accttgcatg agcataacca tgcttagcaa
    27541 ataacatcaa gccactcgta tctctgtcta aacgagtcac gatatgcact tgttggtcta
    27601 ggtaatgatt gtccacataa tatgccttga taaagttagc aatggtattg gagtggatgg
    27661 cacttggaat actggcaaag ccaatgggtt tattaatcac caaaaaatga tcatcctcgt
    27721 gaacaatatc caaatcaaaa gggatggctt caagcttttc aaagggctct tcgtttggaa
    27781 tgtcaatggt gacaacatct cccacttgca ataaataaat ggcattttgt tcaataccat
    27841 tcactaatat attaccgccc ttatatttga ttttagccaa tagtccttta gagacatcat
    27901 aactttttaa aagggttttt acttttattc gtttgtctgc tacaaattca aatctcatga
    27961 gtcaatctct ccaataaagg catccttgac cctttcccaa aagctcgtat gactcggaga
    28021 ggaaacaaaa tgaattttct catcgtcgat aaaatactcc accttcgtca cattttttaa
    28081 ctgataggtt ttattatcaa tggaaatggt ataaattcct aatcgttttg gcactaactc
    28141 aatcttatct tttttgggaa taatgattga tgagcccaag gttctaaaga cacggttatt
    28201 aagactggaa atttccgtca attgcagcgc ttcaatcgtc ggatgcaaga cagcaccacc
    28261 taaagattta ttgtaggctg tgctccctgt cggggtcgat actgaaatcc catcacctcg
    28321 gaagctttca aatttgacat ggttaataat aacatctgct accatcgttt tttcaatacg
    28381 cttaaccgtc gcttcattca aagcacgcgc tttaaccaca cgaccatcat ctaaagtaat
    28441 agcaactttt aaaatcggat aagagatttg ttctcccttg tcttttctta aattatcaat
    28501 taatttatca acttcaaaat ccctataatc ggtataaaag ccaagatgac cggtgtggat
    28561 tcctacaaaa cgtaccttat ctaattcttt ttcatacatg tgaaaggcag ataagagcat
    28621 cccatctccg ccaatagaaa tcacaatatc cggatttttc tttgaaagat agaaatcagg
    28681 atcatcttta aatacggaga aaagtttgga ggcgacgcgt ttactttggt acttaccatt
    28741 tgcaataata gcaactcgtt ttaccttacc tgtataattc atctgtgtca tcactatttc
    28801 ctacaccatc acttaaattt cgtgtcacgg ggtcaaacaa taattgagcc tcccgaatat
    28861 cttctcgaat cttacgcatt tcttcgtcta attctaaagc aattttagca gtcacttcaa
    28921 gacgcttttt aatttcttct gggaagtctc caccatattt ataatttaaa gaatgctcaa
    28981 tggtcgccca aaagttcatt gccaaagtac gaatctgaat ctccgctaag accttttttt
    29041 gaccttcaat ggtgtcaaca gggtactcaa ccaccacatg ataagacctg tagccactgg
    29101 acttcatatt gcgaatataa tctcgttcat aaacaattgt catgtcttgt cgttgacgca
    29161 atagagctaa gacttcttcc acatcatcaa caaactgaac cataatacgt agtccagcaa
    29221 tatcttgaat atcttgtgct atattttctt caataacacc acgtaaaatc attttttctt
    29281 taatactttc aattgactta acacgtcccg taacaaattc aatcggagaa taacgatttt
    29341 gcttacgata ttgcttgcga ataccccgta gttttatttt taattcacca actgtttgga
    29401 tataaggatc taaaaattct tcccaatcta aggtcatcta ttgtctcctt tcttgtcaaa
    29461 gccaggataa taatataaaa ttgaaataac aatttattat agcacaaatt aaaaggaatt
    29521 tcccatgact aacctagaaa tcgaatataa aactctactt acaaaaaatg agtataaccg
    29581 tcttttatct caaatgaaac atgtgacgcc tgttacacaa actaattact atattgatac
    29641 aaaagcattt gatttaaaag ctaacaaaat gtcattacgt attcgaacat ttgtaaatag
    29701 cgccgaatta accctaaaag tgccagaaaa agtggggaat cgtgagtaca atgtccctct
    29761 ttttcttgaa caagcaaaag atatgattaa acatgggaat cttcctgaat caactgctct
    29821 tgatattatt atttcaaaag gtatcaaacc atctgcactg gtaacttttg gcaatttaac
    29881 taccgttcgt cgcgagacag tgataccgat aggtaaattg gccttagact ataacctata
    29941 tgccaatacc aaagactatg aattagaatt agaagtaagt gacgctcttc aaggaaagat
    30001 tgattttgat tcttttttat ctgaacatca cattactttc aaatatgcta aaagcaaagt
    30061 agctcggtgt attaatacct taaaaaagtt caacgataaa taatggctaa aagcgacaga
    30121 aaaactgaaa tttttctgtt tttctgttaa aatagggatg tcaattaaac acttttgggt
    30181 aatgtgactc attaataaaa cagtttaccc aattttattg aagttaagga gctaaatcta
    30241 tcatgactga acgatatgct gacaagcaaa tcaaactgtt ctcactcaca tcaaatcttc
    30301 caattgctga aaaaattgct aaagctgctg gaatccctct tggaaaaatg tcttcacgtc
    30361 aattttccaa tggagaaatt atgatcaata ttgaagaaac agtgcgtgga gatgatatct
    30421 atattattca atccactagt tttcctgtca atgataatct ttgggaatta ctcatcatga
    30481 ttgatgcttg taaacgtgca agtgctaata ccgtcaatat tgtattgcca tactttggtt
    30541 actctcgtca agaccgtgtc gctaagcccc gcgaaccgat tactgctaaa ctagtagcta
    30601 atatgctgac taaagctggt attgatcgtg tagtgacgct tgacttacat gctgttcagg
    30661 tacaaggttt ttttgatatt ccagtggata acctctttac agtccctctt tttgcagaac
    30721 gttacagtaa attaggctta tcaggttctg atgttgttgt cgttagccct aaaaattctg
    30781 gaattaaacg tgctagaagc ttggctgaat atcttgattc cccgattgct attatcgact
    30841 atgcacaaga tgattctgaa cgtgaacaag gttatattat tggtgatgtt tctggtaaaa
    30901 aagccatttt aattgatgat attttaaata ctgggaaaac ctttgcagaa gctgctaaaa
    30961 ttcttgaacg ctcaggcgct actgatactt acgcggtcgc tagccatggc ttatttgctg
    31021 gtggagctgc tgatgtatta gaaacagctc caatcaaaga aattatcgtt acagattctg
    31081 ttaaaactaa aaatcgtgtg ccagaaaacg ttacttatct tagcgccagt gatttaatcg
    31141 cagaagctat tattcgtatc catgaaagaa gacccttaag tccgcttttt tcttatcaac
    31201 ctaaaggcaa aaataacgca tgacttactt tgataacgcc gccaccacac cacttagtcc
    31261 taatgtgatt agggcgatga cagcagctat gcaagataac tttggtaacc cctctagtat
    31321 tcatttctac ggtcgccgag ccaataaaat ccttcgtgaa tgccgacaag ctatcgctag
    31381 aaacttgggg gcaagtgaac agcaaattat agtaacgtcc ggtggaactg aaagcaataa
    31441 tatggccata aaaggctatg ctttagctca tcaagcaaag ggcaaacatc tcatcacaac
    31501 tactattgag caccactctg tgcttcatac catggcctat ctcgaagagc gatttggttt
    31561 tgaggtcact tatttgcctt gtcaaaatgg acaaataaat ttatctgact taaaacaagc
    31621 cttgagagat gacaccattt tggtaagcat aatgtatgcc aataacgaaa caggtgacct
    31681 gttacctatt aaggacattg ggaatctgct caaagaccat caagctgctt ttcatgttga
    31741 tgccgttcaa gctgttggca aactcaagat tattcctagc gaacttggga ttgacttttt
    31801 atctgcttct gctcacaaat ttcatggtcc taaaggatgc ggctttttat acagtaacgg
    31861 acaaccaatc gaccctcttc ttcacggggg tgatcaagaa ggaaagcgac gcgcaagtac
    31921 tgaaaatatg ttaggtatta ttggtatggc acaagctttg actgatgcta tgacttgtct
    31981 tgaccaatca actgatcaca ttattagttt acgtcatcac ttgattagcc tcctagaagg
    32041 actaccctac tatattaatc aaggtactca ttatcttcct catgttctca atattggatt
    32101 tttaggctac caaaatacta ttttactaac acaacttgac ttagcaggca ttgcagtatc
    32161 aactggttct gcttgtactg ctggagctgt taatccaagt catgttttag ctgcgtacta
    32221 tggggatgac tcttctcgtt taaaagaatc aattcgtatc agtttttcag atcaaaatag
    32281 cattgaagat gttaatcaat tagctcaaac attaaaaaat attttaggag gaacagatgg
    32341 cttttgaaaa agaaattaag cttaaagact gtaaatacct ttatacaatc agtccaaaca
    32401 ttaaaaaata taccctaaga gatactacat ttagtcaaac taaagtaggg cactaccaat
    32461 taatacgttt actcgaaaaa atacctaatt caggggatgg tttcccttta aaaatcacta
    32521 ttaataaaga actcacaggg tttaaattag ctatcaccga tcagtctggt cttagattag
    32581 ttaatatttt taaaacaaaa gataatcaaa tccttcaaga taaattttat ttcttgatgg
    32641 acagccttgt agaacgtgaa atttttagca aaacagtcgt ctaatcaact ttaaattttg
    32701 tttttttagt catatcacaa tgtcaataaa tgatttcgct tctattgcta ttaattcatg
    32761 ttgttca
//
LOCUS       DAUGJR010000020        29529 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUGJR010000020 DAUGJR010000000
VERSION     DAUGJR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29529
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.020"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..133)
                     /locus_tag="VH800_000935"
     CDS             complement(<1..133)
                     /locus_tag="VH800_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8362013.1"
                     /translation="MKRIIKTIILVIIIFHGYGSVKSDSENIKDVKLQLNYAYEIIPV
                     "
     gene            complement(381..995)
                     /locus_tag="VH800_000936"
     CDS             complement(381..995)
                     /locus_tag="VH800_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362014.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDEQNKFILDGLQEKVKEVSVS
                     DFSVGESKIKVWLPQAWSVKISREHSPKSSISNSGEQKPLSNSSENKEGQFSKRLPYG
                     TQHTIKLSSQLTKGERVTLTFRDEDFWGAGYCFYRDSLSIKEDKQYEEEIKKIEDDLE
                     RQDLENDALEMFKKQTEREANKPWHQRLSENIQDQWWNFKGLFQ"
     gene            1356..1592
                     /locus_tag="VH800_000937"
     CDS             1356..1592
                     /locus_tag="VH800_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEQ8362015.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            1585..2283
                     /locus_tag="VH800_000938"
     CDS             1585..2283
                     /locus_tag="VH800_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEQ8362016.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLKQGHHVYGVDKSDKPDLSGNF
                     HFIKLDLSSELAPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTANDFEPGGLADWVARETPIGRWTKPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            2359..3318
                     /locus_tag="VH800_000939"
     CDS             2359..3318
                     /locus_tag="VH800_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8362017.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTAKDLA
                     KAHHMPLATSKYEAILGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIARKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVQLSLHGHEPQVINHNKH
                     DHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMAVLERAVHS"
     gene            3651..4988
                     /locus_tag="VH800_000940"
     CDS             3651..4988
                     /locus_tag="VH800_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8362018.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIAILLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKVGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            5161..6543
                     /gene="glmU"
                     /locus_tag="VH800_000941"
     CDS             5161..6543
                     /gene="glmU"
                     /locus_tag="VH800_000941"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEQ8362019.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALAIAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            6574..7128
                     /locus_tag="VH800_000942"
     CDS             6574..7128
                     /locus_tag="VH800_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8362020.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLIQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            7128..7379
                     /locus_tag="VH800_000943"
     CDS             7128..7379
                     /locus_tag="VH800_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362021.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVNFDTKVMTLPEKDDKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            7399..8094
                     /locus_tag="VH800_000944"
     CDS             7399..8094
                     /locus_tag="VH800_000944"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEQ8362022.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQTLMTFLENLPV"
     gene            8245..8586
                     /locus_tag="VH800_000945"
     CDS             8245..8586
                     /locus_tag="VH800_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362023.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNEGYHQHLTD
                     EKSHLQYSKDNAQLQLRNILDGYQNDLGRHYSSYYYYNLRTVMGLSSEQDIEKHYEEL
                     KNKLHDMYNHY"
     gene            complement(8687..9334)
                     /locus_tag="VH800_000946"
     CDS             complement(8687..9334)
                     /locus_tag="VH800_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEQ8362024.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDSFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            9480..10412
                     /locus_tag="VH800_000947"
     CDS             9480..10412
                     /locus_tag="VH800_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEQ8362025.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            10476..11201
                     /locus_tag="VH800_000948"
     CDS             10476..11201
                     /locus_tag="VH800_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362026.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            11202..12056
                     /locus_tag="VH800_000949"
     CDS             11202..12056
                     /locus_tag="VH800_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8362027.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(12204..13010)
                     /locus_tag="VH800_000950"
     CDS             complement(12204..13010)
                     /locus_tag="VH800_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ8362028.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            13227..15632
                     /locus_tag="VH800_000951"
     CDS             13227..15632
                     /locus_tag="VH800_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8362029.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(15702..16055)
                     /locus_tag="VH800_000952"
     CDS             complement(15702..16055)
                     /locus_tag="VH800_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEQ8362030.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            16299..16724
                     /gene="rplK"
                     /locus_tag="VH800_000953"
     CDS             16299..16724
                     /gene="rplK"
                     /locus_tag="VH800_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEQ8362031.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            16830..17519
                     /gene="rplA"
                     /locus_tag="VH800_000954"
     CDS             16830..17519
                     /gene="rplA"
                     /locus_tag="VH800_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEQ8362032.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            17842..18570
                     /locus_tag="VH800_000955"
     CDS             17842..18570
                     /locus_tag="VH800_000955"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEQ8362033.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            18599..19156
                     /gene="frr"
                     /locus_tag="VH800_000956"
     CDS             18599..19156
                     /gene="frr"
                     /locus_tag="VH800_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEQ8362034.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            19265..20122
                     /locus_tag="VH800_000957"
     CDS             19265..20122
                     /locus_tag="VH800_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8362035.1"
                     /translation="MNDLLATVITGLIKEENANDYFIHKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIEQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHSSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKASFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            20195..20704
                     /gene="msrA"
                     /locus_tag="VH800_000958"
     CDS             20195..20704
                     /gene="msrA"
                     /locus_tag="VH800_000958"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEQ8362036.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWTQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            20701..20916
                     /locus_tag="VH800_000959"
     CDS             20701..20916
                     /locus_tag="VH800_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEQ8362037.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            21072..22241
                     /locus_tag="VH800_000960"
     CDS             21072..22241
                     /locus_tag="VH800_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8362038.1"
                     /translation="MIITKKSLFVTSVALSLVPLATAQAQEWIPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATNL
                     TVQAPASSPASVSHVPSSEPLPQASATSQPTVPMAPPATPSDVPTTPFASAKPDSSVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEAPTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMN
                     AGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYA
                     IDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            22555..24327
                     /locus_tag="VH800_000961"
     CDS             22555..24327
                     /locus_tag="VH800_000961"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEQ8362039.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKENETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            24486..25538
                     /locus_tag="VH800_000962"
     CDS             24486..25538
                     /locus_tag="VH800_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEQ8362040.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            25584..26159
                     /locus_tag="VH800_000963"
     CDS             25584..26159
                     /locus_tag="VH800_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEQ8362041.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQGTKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            26318..26815
                     /gene="ybeY"
                     /locus_tag="VH800_000964"
     CDS             26318..26815
                     /gene="ybeY"
                     /locus_tag="VH800_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEQ8362042.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            26796..27203
                     /locus_tag="VH800_000965"
     CDS             26796..27203
                     /locus_tag="VH800_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEQ8362043.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            27323..28219
                     /gene="era"
                     /locus_tag="VH800_000966"
     CDS             27323..28219
                     /gene="era"
                     /locus_tag="VH800_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEQ8362044.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFHSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            28239..28715
                     /locus_tag="VH800_000967"
     CDS             28239..28715
                     /locus_tag="VH800_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8362045.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WTIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
BASE COUNT         8966 a         5250 c         6411 g         8902 t
ORIGIN      
        1 ctactggtat gatttcgtat gcgtaattta attgtagctt aacgtcttta atattttcac
       61 tatctgattt tacacttccg tacccatgaa agattattat aactaaaatt attgttttta
      121 ttattctttt catacctctc ctcgttcacc tcgtacccca caaactactt tatcctaaaa
      181 aaccataaaa tcaacattga ggactttttt ggttcccata aattgttaac tatgtcattt
      241 tagagcaatc atatagagac taagatataa ttttaccaaa gttttgaaag ctattgaaga
      301 gtatcttgat tttgtctagg ttctaagcac ctgtaagggt gctttttgtg ctttagccaa
      361 cctcatagtc tagtaaaccc tcactgaaac agtcccttaa agttccacca ctgatcttgg
      421 atgttttcgc ttaaccgctg atgccaaggt ttattagcct ctctttcggt ttgtttttta
      481 aacatctcta gtgcatcatt ttcaagatct tgtctctcta ggtcatcctc aattttctta
      541 atttcttctt cgtattgttt gtcttctttt atggatagtg aatctctata gaagcagtaa
      601 cctgctcccc aaaaatcttc atctctgaat gtcaaagtga ctctctcacc ttttgtaagt
      661 tgggatgata atttaatagt atgttgggta ccataaggta atcttttaga aaattgacct
      721 tctttattct ctgagctatt gcttaaaggt ttttgttctc cagaattaga aatgcttgat
      781 tttggtgaat gttctctaga aattttgacc gaccaagctt gaggaagcca gactttgatt
      841 ttagattctc caacagaaaa atctgataca ctaacttctt ttactttttc ctgtaatcca
      901 tcaagtataa acttattctg ttcatcctcc gctctgacgc tactagttac cccgatggca
      961 aagagtgcca gtagcaaggt taatgttttt ttcatttttt cctctccttt tgctcatttt
     1021 taagataaga cttattatac caattcttgc gctaaaaaga tagggagttt atgtcttgtg
     1081 gttgggaaat ggcgtgacta ttcttggtag gggcagacag gttttttcct agccagttgc
     1141 taaccgttac ccttttacct ttgcaagccg tttgggcatc aggtcgtgtt ttgaggttgc
     1201 caatactttt agttgctttt tgacaaaaat gcgttatgat agactaaata aaagaagata
     1261 gcattttcga tgaatgatgc gtgagtccac aaatttattt ttaggagttt atagactgcc
     1321 taaaagtgtc tatttcgtca ataaaggaga acaatatgac atttgaagag attttaccag
     1381 gtttaaaagc caagaaaaaa tatgtacgta caggttgggg tggcgctgaa aattatgtgc
     1441 agttgtttga tacccttgaa gtggatggga aagtactaca ggcgacgcct tattttctga
     1501 ttcatgttac tggtgcaggt gaaggttttt ccatgtgggc accgacacca tgtgatgtgt
     1561 tagcagagga ttggattgag gtcaatgact aaagttgttt tagtgacggg ctgtgctagt
     1621 gggattggtt atgcacaggc ccgctatttt ttgaaacaag ggcatcacgt atatggtgtg
     1681 gataagtcgg ataaaccgga cttaagcggt aactttcact ttatcaaatt ggatttatcc
     1741 tctgagttag ccccactatt taaagtggtc cccagtgttg atattttgtg taatactgca
     1801 gggattttag atgcctacaa gccactttta gacgtcagtg atgaagaagt ggaacaccta
     1861 tttgatatta atttttttgc gacggtgaag ttaacacgtc attatcttag acgtatggtg
     1921 gaaaagcagt caggtgttat catcaatatg tgctcaatag caagttttat agcgggtggc
     1981 ggtggtgttg cctatacgag ttctaagcat gcccttgcgg gattcacgcg ccagctggct
     2041 ttggattacg ccaaagatca gattcacatt tttggtatag caccaggtgc tgtcaaaacc
     2101 gctatgacgg ctaacgattt tgagcctggt ggcttagcag actgggtagc tcgtgagacg
     2161 ccaattgggc gttggactaa accagatgaa gttgctgaat taacgggatt tcttgcttca
     2221 ggaaaagcga gatcaatgca aggcgagatt gtcaaaattg acggtggctg gactttgaaa
     2281 tgatcacatg ccttagcttg agctggcgca gtaagcccta gaggtgtgat gagtcaaaca
     2341 gtcaaaggag atgaacaaat gaaattagcg gttttgggga caggtatgat tgttaaggaa
     2401 gttttgcctg tcttgcagaa aattgatggt attgatttag ttgctatctt atcaacagtt
     2461 agaagtttaa cgacagctaa agacctcgct aaggcacatc acatgcctct agctacgagt
     2521 aaatatgagg ctatcttagg caatgaggag attgacacgg tttatattgg actgccgaat
     2581 cacctgcatt ttgcctatgc taaggaggcc cttctagctg gcaaacatgt catttgtgaa
     2641 aagcccttta ccatgacagc aggagaatta gatgaactgg tggtaatcgc tagaaaacga
     2701 aaactcattt tgttagaagc gattacgaat cagtacctga gtaacatgac ctttatcaaa
     2761 gagcatcttg accaacttgg cgatatcaaa attgtagaat gcaattattc acaatattct
     2821 tcacgctacg atgccttcaa acgaggtgat atcgcgccag cttttaatcc taaaatgggt
     2881 ggtggagctt tacgtgattt aaacatctac aacattcatt ttgtggtagg gttatttggt
     2941 cgccctaaaa cggttcaata tttagccaat gtcgaaaaag gcattgacac ctcaggcatg
     3001 cttgtcatgg actatgagca gtttaaagtg gtgtgtatcg gggccaaaga ctgcactgca
     3061 gaaatcaaat caaccatcca aggtaacaaa gggtcactgg cagtgcttgg agcaacaaat
     3121 accctccctc aggttcagtt aagtctacac ggtcacgaac cacaagtgat taaccacaac
     3181 aagcatgacc accggatgta tgaagagttt gtcgctttta gggacatgat tgaccaaaga
     3241 gactttgaga aagtgaatca ggctttggaa catagccgag ctgtcatggc tgtgttggag
     3301 cgcgctgttc attcgtgatg gtaatctggt agccattgcc ttttgtgcag gtgctatggt
     3361 aatggttgaa agacgtgttt tcacgagggg gagccccctc gtgctttttt ggcaaaaata
     3421 acttgttcag gatttgggct ttctttgtga gatgagagat gcctgacgaa ttgatttgat
     3481 taaaataatg ataaagccaa acgatttaag aaatgaccgt tcggaaattc tgccccaaag
     3541 gggctctaga agcagtaaaa tcgaatttgt aagcgttgac actgttgcat aactctgtta
     3601 cactaagaga atgtcatgac aaaaattaca gtgtaggagt ttaattgttt atggaagagg
     3661 attataacaa aagagaacct gagaagttta cgcaatttct gcgccgtcaa aaggtcgtct
     3721 tttttgtcgc attttttggt tatgtgtgtg cttacttggt acgcaacaat ttcaaactaa
     3781 tgtcaaacac tattatggtg caaaatggtt gggacaaggc tcaaattgcg atcttgttat
     3841 cgtgtttgac cgtttcttat ggcttagcaa aattctatat gggagcctta ggggatcgtg
     3901 ttagcttgag gaagctcttt tcaatcagct tgggtgcaag cgctttgatt tgtattttaa
     3961 ttggtttttt caatagttca atggtggtat taggaatact gctagtcttg tgtggtgtcg
     4021 tacaaggtgc cttggcacct gcctcacaag ccatgattgc caattatttt ccaaataaaa
     4081 cacgcggcgg agccatcgct ggatggaaca tttctcaaaa catgggatca gccctcttgc
     4141 cattaaccat cgccttgctc accagtatgg gcttggtggt accagctaat ggcaatattt
     4201 tacttgcctt tttaatccct ggcgttttag tgttcttgtt tgctttgtgt tgctggaagc
     4261 ttggcggtga taaccctgag tctgagggac ttgactctct tcgaacgatg tatggtgatg
     4321 cgggcgagtc agctgttgcc agtgaagaag aaaagcataa cctgtcttat tggcaactca
     4381 tctggaaata cgttttttgt aacccgtcgc tcttacttgt tgctgctgtc aatgtggccc
     4441 tttattttgt tcgttttggg attgaagact ggatgccgat ctacttgtca caagtagcca
     4501 atatgtcaga ggctcatatc cattttgcga tttcaatgtt agagtgggtc gctattccag
     4561 gctcgctggt atttgcgtgg ttagcggttc gttatcctaa taaaatggcc aaggttgggg
     4621 ctattgggct ttttgtgtta gcggctattg tctttgtcta tgaacgcttg actgccacag
     4681 gtgctccaaa ttatttcttg ttgcttgtta ttgcaggtat tttagggtca ttgatttatg
     4741 gcccacagtt gatcgtgaat attttaacaa tcaactttgt tcctttaaat gttgcaggaa
     4801 cagcgattgg ttttgtagga gtaacagctt atctcatcgg caatatggga gcaaactggc
     4861 tgatgccgat tttggcagat ggttttggct ggttttggtc atatattgtc gttgcagcct
     4921 tatctgcttt ttcagcggtt ggttatttga ttttagccaa acgtgaggaa gaaatcatca
     4981 aagattagct aggcaaatgc ctaagaaaga cagacttatt gctgaagtcc tgtctttttt
     5041 agttatcaca agccgcaaat gacactataa aagacaagaa aatgctagga tgtttcagga
     5101 aaaaaagaga aaatatgcta taatgagaag gtatttaaat tatatagtaa ggaaaaacaa
     5161 atgacaaatt atgccattat tttagcagcg ggcaaaggga ctcgcatgac ttctgatctc
     5221 ccaaaagttc ttcataaagt atctggacta accatgcttg agcatgtttt tcgtagtgta
     5281 aaagcgatta gtcctgaaaa atccgtgacg gttattggtc acaaatcaga aatggtacgt
     5341 gctgtcttag cagatcaatc agcctttgtc catcaaacag agcagttagg aactggccat
     5401 gccgtgatga tggcagaaac acaactagaa ggactagaag ggcatacctt ggtgattgca
     5461 ggagatactc ccttgatcac tggagaaagc ctgaagagtc tgattgattt tcatgtgaat
     5521 cataaaaatg tcgccactat tttaacagct acggctcaag atccatttgg ttatggtcgt
     5581 attgttcgca acaaagatgg cgaagtgatc aagattgttg agcaaaaaga cgccaatgag
     5641 tatgagcaac aattaaaaga aatcaataca ggaacctatg tgtttgataa caagcgtctc
     5701 tttgaagcgc tcaaatgcat cactaccaac aatgctcaag gagagtatta cctgactgac
     5761 gttgtggcta tttttagagc aaacaaagaa aaggtaggag cctatatcct gagagacttc
     5821 aatgaaagtc tgggagtaaa tgatcgtgtg gccttagcaa tagctgaaac agtgatgcgt
     5881 cagcgcatta cccaaaaaca tatggtcaat ggggtgactt tccaaaatcc tgaaactgtt
     5941 tatattgaaa gcgatgttga gattgctcca gacgtcctta tcgaaggaaa tgtgacctta
     6001 aaagggcgta cacatatcgg ctcaggaact gtcttgacga atggtactta tattgtggat
     6061 tctgaaattg gtgataactg tgttgttacc aattcgatga tcgaatcatc tgttttagct
     6121 gcaggagtta cggttggccc ttacgcccac cttcgaccgg gaacgacctt agatagggaa
     6181 gtccatatcg gtaactttgt cgaggtcaag ggttctcaca ttggtgaaaa aacaaaggct
     6241 gggcatctga cttatattgg aaacgctcag gttgggtctt cagtcaatgt tggggctgga
     6301 accatcactg tcaactacga cggccaaaac aaatatgaaa cagtcattgg agatcacgct
     6361 tttattggga gcaactcgac tctcattgca cctttggaag ttggggatca cgctttaaca
     6421 gcagcaggtt caacgatttc aaaaacagtt cctatcgata gcattgctat tggtcgtagc
     6481 cgccaagtca caaaagaagg ttatgccaag cgcctagcgc atcacccaag tcgaagcaaa
     6541 taattcaaga tctatttagt aaggaggcca ggcatgaaat ttgaagaaaa aacgcttaag
     6601 agacaaacag tttttgatgg tcatattttt aaagttgttg tggatgatgt tgaacttccc
     6661 aacaatctgg ggcaatccaa gcgagaatta atttttcatc gtggtgccgt tgctgttttg
     6721 gctattactc ctgaacgtaa gattgtcctt gtcaaacaat accgtaaggc tattgaacgt
     6781 gtctcatacg agatcccagc gggtaagcta gagattggtg aggaaggctc aaagctaaaa
     6841 gctgctgcac gtgagctaga agaagaaaca gcctatacgg ggacattgac gtttttgtat
     6901 gaattttata cagcgattgg tttttgcaac gaaaaaatca cacttttctt agcgacagac
     6961 ctaatacaag ttgccaatcc caaacctcaa gacgacgatg aagttatcga ggtcttagag
     7021 ttgacatatc aagagtgcat ggacttagtc gctcaaggta aacttgctga cgctaaaacg
     7081 ttgattgctt tgcaatacta tgccttacat tttggaggtg agcagtgatg ggaaggccat
     7141 tgttgaccga tgatatcatc gaaaaagcga gacgaatgga aacatttgag ccagatgatg
     7201 ctgtaaactt tgacacaaaa gtaatgacgc taccagaaaa agatgataaa gcacgcattt
     7261 ataaaagtcg tcggattgaa aatgccaaac gcagccaatt gcaatctaaa ttaaatgtga
     7321 ttttgatagc tgttatgctg ttaattgcca tcttggtata tgctatcttt tatctttaaa
     7381 aaaacgtaag gaaatgatat gaaaatagga attattgctg ctatggagga ggagttgtcc
     7441 ctgctcttag caaatctttt ggatgctcaa gaacatcagg tgctttcaaa aacttactat
     7501 acgggtcgtt ttggcaagca tgagctcatt ttggtacagt cgggtgttgg aaaagtgatg
     7561 tctgctatga cagttgcgat cttggttgag catttcaaag cccaagctat tatcaataca
     7621 ggatcagcag gggcagtcgc ttcacattta gcgatcggag atgtggtggt tgcagatcgg
     7681 ttagtgtatc atgatgtgga tgctactgca tttggttatg cttatggtca aatggctggt
     7741 caaccattat actatgattg tgatccacag tttgtggcta tcttcaaaca agtcctaaaa
     7801 cacgaaaaga caaatggcca agttggtttg attgcaacag gagacagttt tgttgctggt
     7861 caggacaaga ttgaccagat caaaacagct tttagcgacg tgttagcagt agaaatggaa
     7921 ggcgcagcta ttgctcaagc agcacatact gcagggaaac ccttcatcgt tgttcgtgcg
     7981 atgagtgata ccgcagcgca tgatgccaat attacttttg atcaatttat tatagaagct
     8041 ggcaagcgtt cggcccagac attaatgaca tttttagaaa acttacctgt ttaactcact
     8101 ttatcgtgag acaattagct ggataatctc tattttagga gtctggtcac ttcttgtttt
     8161 gaaacctaaa aataagaatt gcaatcactt gaccaaacgc tataatgggt taagtaacga
     8221 tagattacta aaaggagtct aaaaatgaca ctaaaaaaac actattatct tctcagcctg
     8281 ctagctcttg taacggttgg tgctgccttt aacacaagcc agagtgtcag tgcacaagtt
     8341 tatagcaatg aagggtatca ccagcatttg actgatgaaa aatcacacct gcaatatagt
     8401 aaagacaacg cacaacttca attgagaaat atccttgacg gctaccaaaa tgacctaggg
     8461 agacactact ctagctatta ttactacaac ctaagaaccg ttatgggact atcaagtgag
     8521 caagacattg aaaaacacta tgaagagctt aagaacaagt tacatgatat gtacaatcat
     8581 tattaagtca aaggcttaaa aatggcgact agcccctcaa aaaaagaggc cacactcatt
     8641 taaatttaaa tgagtgtggc ctcttttttt gaggagacgc aaggggttaa agggctgtga
     8701 cataaagttg cttagcaata ttttcaggga tgacaagttc cttgtcgcca taacaaatcg
     8761 tataggtttt tgcaaaggta tcaatttgag ttaaggttag ctcggtattg atattgaggt
     8821 gatgtgcttc tagatactgg attaaatcaa agtggtcgtg gattctgctt agacgaaacc
     8881 gtcccaactc cgtgatggtg ttgagagttg tagtgttcat ttcgacaaga ggctgaccat
     8941 agcgaggaat agtccctccg tgtgggcaga aatctggaaa atcaaggatc ttgtctaaac
     9001 ggtcgataaa ggagtctgag acagtgtgct ctaagacttc agcttcttgg tgcacttctt
     9061 gggtattata gcccagctga tgaatcaaaa atacctcaat caagcggtgt ttgcggtaga
     9121 ggttagcaac aagagcatag cctttgtctt ttagcaaata gccttttgct ttatctttga
     9181 caatccagcc ttgtgaaatc atttttttaa tcatctctga aacggcaggt gccgaaacgt
     9241 gcatcttttc tgcaaccatt ttatttgtaa tcttgggttc ttgttctcca atttcataaa
     9301 tacatttcaa gtaatcttct ttattaggcg tcatatcgtt tggcctttct cttatttata
     9361 atgattatta tatcagaatt tttaggaaaa agcttgacaa aaagcctaaa agaggatatc
     9421 cttatagcat aattaactaa acttaattaa ataaataata tatcctaagg agagaaatga
     9481 tgggaaagag aatgagcctc attttgggtg cttttttatc tgtttttctt ttagtagctt
     9541 gttcgtcaac tggcactaaa actgctaaga gtgataaatt aaaagtcgtg gcaaccaatt
     9601 caattattgc cgacatgaca aaagctattg ctggtgataa aatcgatctg cacagcattg
     9661 tgccaatcgg tcaagaccct catgagtacg aaccattacc agaagatgtt gaaaaaacaa
     9721 gtaatgctga tgtgattttc tataatggta tcaatctaga agatggcggg caagcttggt
     9781 tcaccaaact agtgaaaaat gctcaaaaaa cgaaaaacaa agattacttt gccgtgtctg
     9841 atggcattga tgtgatttac ttggaaggtg caagcgaaaa aggaaaagaa gatccacatg
     9901 cttggttaaa tctcgaaaac ggaatcattt attcaaaaaa cattgccaaa caattgattg
     9961 caaaggatcc taaaaacaaa gaaacttatg aaaagaacct aaaagcttat gtggctaaat
    10021 tggaaaaact agacaaagaa gccaaatcaa aatttgatgc tattgcagaa aataaaaaat
    10081 tgattgtgac tagtgaaggc tgcttcaagt acttttcaaa agcttacggt gtcccatctg
    10141 cttatatctg ggaaattaac accgaagaag aaggaacacc agatcaaatt tcatcattga
    10201 ttgaaaaact aaaagtcatc aagccatctg cgctttttgt agagtcaagt gtcgatagac
    10261 gccctatgga aactgtttct aaagatagtg gtattcctat ttattctgag atctttacag
    10321 attcaattgc taaaaaaggt aaacctggcg atagttatta tgctatgatg aaatggaacc
    10381 ttgacaaaat ttctgaaggt ctagcaaaat aagataacaa taaagcacag cgattttagt
    10441 gttgtgcttt gttttattta tgtaaaggag acaaaatgat tacaactaac aatctttgtg
    10501 tgacctacga tggcaacagt aatgctttag aagcgattaa tgtgacaatt gaaggtcctt
    10561 ctatcgttgg tattattggt cctaatggag ctggaaaatc aacctttatg aaagctatct
    10621 taaatcttat tgattatcaa ggtcacgtaa cggttgatgg caaagatggt cgtaagcttg
    10681 ggcatacagt agcttacgta gaacaacgaa gcatgattga ctataatttt cctattactg
    10741 ttaaagaatg tgttgcgcta gggacttata gtaaattagg cctttttcgc cgagtaggaa
    10801 aaaaacaatt tgagcaggtt gataaggttc tcaaacaagt tggtttagaa gactttggcc
    10861 atcgaccgat aaaatcctta tctggtggtc agtttcagcg gatgttggtt gcgcgttgct
    10921 tgattcaaga atcagactat attttcttag atgaaccgtt tgttggcatt gactcggtca
    10981 gcgaaaaaat cattgtagat cttttgaaag agctcaaaat ggctggcaaa acgattttaa
    11041 ttgtacatca tgatttgagc aaagtagagc attattttga caaactcatg attttaaata
    11101 aacatttggt ggcttatggc aacgtttgtg aggtatttac tgttgatacc ttgtcaaaag
    11161 cttatggcaa tcatttgatt ttaggaaagg agatggtgta aatgtctatg aaattttttg
    11221 agggcttgat gtcataccac tttttacaaa atgcactgat aacggctgta gtcattggta
    11281 tcgtctcagg tgctgtaggg tgttttatta tccttaggtc aatgtctctt atgggtgatg
    11341 ccatctcaca cgctgtttta ccaggggttg ctttgtcatt tattttagga gtcaattttt
    11401 ttattggagc gattattttt gggttattag cttctgttat tattacttat atcaaggaaa
    11461 actctgtcat taaaggagat acggctattg gtatcacctt tagctctttt ttggcactgg
    11521 gagtcatctt gataggggta gccaatagtt cgacggactt atttcatatt ttgtttggga
    11581 atattttagc tgtgcaagat agcgataagt ggattactat tggtgtttcg atttttgttt
    11641 tagtggttat tagtctcttt ttcaaagaac tattattaac atcatttgat cctatcttag
    11701 ccaaatcaat gggtgtgaag gtcaatgcgt atcattattt gttgatggtc ctattaactt
    11761 tagtggctgt tacggcgatg caaagcgtgg gtactatctt gattgttgcc ttattgatta
    11821 cgccagcagc gacagcttat ttatatgcta atagcttaaa agtaatgtta gtgatgtcat
    11881 ctttactagg cgctttagca tcggttttag ggctttattt gggctatacc tttaatgttg
    11941 ccgcagggtc aagtatcgta ctgacttctg cgatgatgtt tttgatcagt ttctttgttt
    12001 cacccaagca aggctacctt aaaagatgga tgcaaaaaaa agaaaaaaca ccttaaactt
    12061 ttcgctttaa acaccttagt ggtttgcaaa tagtagcaaa taacatcaaa gggtgttttt
    12121 tatatgtcat caaaagacca taaaaaacct tatcaaacca aggtatttag cctattatct
    12181 gataaggttt ttttaagcat gatttagttt ttaaagcgat aatctttgac aatgtcaatt
    12241 gaggtaatcg taatgtcttg ttctggttta tcattttggt tgatagaagt agcggcaatt
    12301 ttatcgacaa catccatacc atcaatgact tgaccaaata cagtataacc gccatctaag
    12361 cttggattgc cgccatgctc ataggcagag atgataggtt ttgggtagtt ggtacttgat
    12421 aatcccttgc tttgattttt cttgttttgg ttgatataaa attggctacc gttagtatta
    12481 gcaccagcat ttgccatggc aagagcaccg cgaatatgat ataaaaatgg agagatttcg
    12541 ttgacaaagc cattgccagc atctttttta ggatccttgc ctttccaaat cgattcacca
    12601 cctgtgccat ctcctttggg gtcacctgat tgaatcataa agtcgttgat cacacgatgg
    12661 aaggtaaggt tatcatagta gcctttttta gcatgggtga ggaagttctc aacagctaag
    12721 ggagcatatt ttgggaataa cttaagggta atgtcccctt gacttgtcct cattacgacc
    12781 ttagcttctt ctttgccgac ttctttggtt agttgtggaa attggctagc atcagctttg
    12841 agagcttttt gaatgctttc ttcataggct ttagaagctg cttcgctttc ttctttggca
    12901 gttttttcat caatgtattt atcgcctttt atagcgcggt caacagattc acaagcactc
    12961 aaactaagta aactaatggc tactaaactg agagataata attttttcat gtctactcct
    13021 aagaatgatt ttctttattt tatcataaaa tgcaacagaa aatagtagta aagagttaaa
    13081 aacgcctatt tttgtgtttt atgatctaac cttggttaaa aggctgctac gactgttatt
    13141 atagcacaag atgctataga aaaacttaaa acaccttggt tttttagagc tatttcctaa
    13201 tagttaaaaa atggtataat agtgttatgg ttaaaagaaa tcaaagaaaa aaaagtgcgc
    13261 ctaagaagcg tttaacaaaa gcagaagtgg aaaagcaacg tgccattaag aggatgattt
    13321 tatctgtttt aatggctttg ttgcttattt ttgcgatgct tcgcttgggc gtctttggtg
    13381 tgacaactta taatatgatt cgttttttgg tgggtagttt agcctatccg tttatgtttg
    13441 cctggttaat ttacttattt tgttttaaat ggttacggca aaaagatgga atgattgcgg
    13501 gagttgttat tgcctttttg ggattgctag ttgagtggca cgccttctta tttgcgatgc
    13561 ctaggatgct tgatcaagat atttttctag gcactgctcg gctaattaca agagatttac
    13621 tagccctgcg cgtgactgaa tttgttggtg gaggaatgct tggtgcatta ctttataaac
    13681 ccatagcctt tttattttcg aatatcggct cttactttat tggttttttg tttatcttat
    13741 taggattatt tctaatgacg ccttgggata tctatgatgt gagtcacttt gtgaaagagg
    13801 ctgttgataa actagcagtg gcttatcagg aaaataaaga aaagcggttc atcaaacgag
    13861 aagagcaccg cttacaagct gaaaaagagg ctttagagaa acaagcacaa gaggaagaaa
    13921 aacgtctagc agaattgacg gttgatcctg agacgggaga gattgttgag gatagtcagt
    13981 ctcaagtcag ctatgatttg gctgaggata tgacaaaaga accagagatt cttgcttatg
    14041 atagtcacct caaagacgat gagacaagct tatttgatca agaagacttg gcttacgctc
    14101 atgaggaaat tggggcttat gactctttat ctgctttagc atcttctgaa gatgagatgg
    14161 atatggatga acctgttgaa gttgatttca caccaaaaac ccatcttctt tataaacttc
    14221 caacgataga tttatttgca ccagataagc ccaaaaacca gtccaaagag aaaaacttag
    14281 tccgcaaaaa tatcaaggtg cttgaagata ccttccaaag ttttgggatt gatgtcaagg
    14341 tagagcgagc agaaatcggg ccttccgtca ccaaatatga aatcaagcca gctgtcgggg
    14401 tccgagttaa tcgtatttca aatcttgctg atgatttggc acttgctctg gctgctaaag
    14461 atgttcgtat tgaagcacca attcctggaa aatccttaat aggtattgaa gttcctaact
    14521 cagaaattgc aacggtttct ttccgcgaac tttgggaaca atctgatgcc aatcctgaaa
    14581 accttttaga agtaccacta ggtaaagctg ttaatggcaa tgcgcgcagt tttaacttag
    14641 ctagaatgcc gcatcttttg gtagctggtt caactggttc aggtaaatct gtggcagtta
    14701 atggcattat ttcaagtatt ttgatgaagg cacgtccaga tcaagttaag tttatgatga
    14761 ttgaccccaa aatggttgaa ttatctgttt ataatgatat tccacattta ttaatcccag
    14821 ttgtaaccaa tccgcgtaaa gccagtaagg cactccaaaa agtggttgat gagatggaaa
    14881 accgctacga gttatttagt aaaattggtg tgcgtaatat agcaggttat aatacaaagg
    14941 ttgaagagtt taatgcttct tctgagcaaa aacaaatacc gttgccttta atcgttgtca
    15001 ttgtagatga attggctgac ttgatgatgg tggctagtaa agaagttgaa gatgctatta
    15061 ttcgtttggg acaaaaagca cgtgctgcag gtatccatat gattcttgca actcaacgtc
    15121 cctctgtaga tgttatttct ggtttgatta aagcaaatgt tccgtcgcgt atggcatttg
    15181 ctgtttcaag tggtactgat agccgtacga tccttgatga aaatggtgct gaaaagctct
    15241 tgggacgggg tgatatgctc tttaagccga ttgatgaaaa tcaccctgtt cgcttgcaag
    15301 ggtctttcat ctcagatgat gatgtggagc gtattgtcaa ctttatcaaa gaccaagctg
    15361 aagcggatta tgatgacgcc tttgatcctg gtgaagttag cgacaatgat cctggttttt
    15421 ctggaaatgg cggagctgct gaaggtgatc ctctttttga agaagcaaaa gccttggtct
    15481 tagaaacaca aaaagctagt gcctcaatga ttcaaaggcg tttgtcggtt ggatttaatc
    15541 gtgccacgcg cttgatggat gaattggaag aagcaggtgt tatcggtcca gcagaaggaa
    15601 ccaagcctcg taaggtattg cagacaaact aaaagaacct gacgtctcat gatgagatgt
    15661 taggttcttt ttttgtgatg tcaagccagt tgatgagatg cctatgctaa tgtaaaaata
    15721 aagataacta gaatcaggta gaaaataacg gtgactaaaa agccaactcg ccaaaatagc
    15781 ttcataaagc gatggtaaga aaacgactga gttcggatga ctagcagtag tgaaatgacg
    15841 atggctagca gcgacatgat aataaggtaa taaggcagta aattatgggt gaaaaatttt
    15901 cctgagacaa gcacaatttc tatcgcaaaa agtaaaagtg cgacatctgg aaatttaaat
    15961 ccctttttat taagtttaaa taaagaggtt acaatcatgg caaaaagagg cgttactatc
    16021 aagaaagcta aggcagttaa tttatagatc atcataggtc tattttatac tcaaatccct
    16081 tacttgtaaa ctgatactta cctgttgtga tagaaaatga tctttgagag ggaaagcgtc
    16141 tacttcaatt taaacattgc aaaaggcatc agctatttta acaaaaagac ttgatttatt
    16201 ttggcaataa gctataatgg taaggtatgc aatattgcat atctgtggga ggtaaaaatc
    16261 tcaattaccg ccaaaaccac aacaggagga tttttaaaat ggctaaaaaa gtcgaaaaac
    16321 ttgtaaaact tcaaatccct gctggtaaag ctacaccagc tccaccagtt ggaccagctc
    16381 ttggtcaagc aggtatcaac atcatgggct tcactaaaga atttaacgct cgtacagctg
    16441 atcaagctgg tatgatcatc ccagttgtta tctcagttta tgaagacaaa tcatttgatt
    16501 tcatcactaa aacaccacca gctgctgttc ttttgaaaaa agctgcaggt gttgaaaaag
    16561 gatcaggtac acctaacact actaaggttg cgacagttac tcgtgcacaa gtacaagaaa
    16621 ttgctgaaac taagatgcca gatttgaacg ctgcaaacat tgaagctgca atgcgtatga
    16681 tcgaaggtac tgctcgttct atgggattca ctgttactga ctagtcagtc aagaacccct
    16741 attacccgca cgacttcatc ataagagatg agtgacgtgg gagattttaa atcaaatcga
    16801 tatgaccaca ttacaaggag aattttaaaa tggctaaaaa aagcaaacaa atgcgtgctg
    16861 cacttgaaaa agtagatagc acaaaagcgt acagtgtaga agaagctgta gcattagtaa
    16921 aagaaacgaa cttcgcaaaa tttgatgcgt ctgttgaagt tgcttacaac ttgaacattg
    16981 acgttcgtaa agcagaccaa caaatccgtg gcgcaatggt attgccaaac ggaactggta
    17041 aaacacaacg tgttcttgtt tttgcacgtg gtgcaaaagc tgaagaagca aaagcagctg
    17101 gtgcagactt cgtaggtgaa gacgaccttg ttgcaaaaat caatggtgga tggcttgact
    17161 ttgacgttgt tatcgcaacg ccagacatga tggctatcgt aggtcgtctt ggacgtgtcc
    17221 ttggacctcg taacttgatg ccaaacccta aaactggtac agtaacgatg gatgttgcta
    17281 aagccgttga agagtctaaa ggtggtaaaa tcacttaccg tgctgacaaa gcaggtaatg
    17341 ttcaagctct tattggtaaa gtttcatttg atgctgacaa attggttgaa aacttcaaag
    17401 ccttccacga tgtaatggct aaagctaaac ctgcaacagc taaaggaact tacatggcaa
    17461 acgtctcaat cacatcaaca caaggtgttg gtatcaaggt tgatcctaac tcactttaag
    17521 aaaaaaatta gggcatcgcc taatcatagc aaaaagacaa atttctgaag acaaatcttc
    17581 actagaggtt tgtctttttt atggtttaaa atgggatgca aacaaaaaag tgtaggcgat
    17641 aataccatga aaggagttga ttctcttaat gagatgtggt gttaacacat catgagctca
    17701 caaaaaatga taaaggaagt atcggtggtg ttaaaaaaag ggattttaat tgacatttat
    17761 tagcctctaa aatgtccttt ccctattcat aattgagggt ttgtggtaaa atagtaagga
    17821 caaactaagg agaacatagt agtggaacct aaatatcaac gtatattaat taagttatct
    17881 ggtgaagcat tagcaggtga aaaaggagtt ggcattgaca ttccaactgt tcaggctatt
    17941 gcaaaagaaa ttgccgaagt tcatgtgtcg ggagtacaga tcgctcttgt tattggtgga
    18001 ggcaatctct ggcgtggaga gcctgcagca gacgctggaa tggaccgtgt tcaggctgat
    18061 tacactggca tgcttggaac ggtgatgaat gccctagtca tggctgatag tcttcaacat
    18121 tatggtgttg atacccgtgt gcaaacagct attcctatgc aaaatgtagc agaaccttat
    18181 attcgcggac gtgccttgcg ccatctagaa aaaaatcgga ttgttgtttt tggagctggt
    18241 attggctcgc cttatttttc aacagacacc accgcggcac tgcgtgctgc tgagattgaa
    18301 gcagatgcta ttttaatggc aaaaaatggt gtggatgggg tctataatgc tgatcctaaa
    18361 aaagatgcta atgcggttaa atttgatgaa ttaacacatg gtgaagtgat caaacgtggt
    18421 ctcaaaatca tggatgcaac ggcatcgacc ttatcgatgg ataacgatat tgatttggtg
    18481 gttttcaata tgaatgaagc tggcaatatt caacgtgttg tctttggaga acatattgga
    18541 actactgtat caaataaagt ttgtgactaa aagttagaaa agaaagagag taattatcat
    18601 ggcaaatgca attattgaaa ctgcaaaaga acgttttgca caatcccatc agtctttatc
    18661 acgtgaatat gccagcattc gtgcgggtcg tgccaacgct agtcttttag accgtatcca
    18721 agttgattat tacggggcac cgacaccatt aaatcaattg gcttcaatca ctgtaccaga
    18781 agcgcgtgtc ttattgatct cgccttttga taaatcttct atcaaagata tcgagcgcgc
    18841 tcttaacgca tcagatttag gcattacacc tgctaacgat ggctctgtca ttcgtttggt
    18901 tattccagct ttgaccgaag aaacacgtaa agaattagcc aaagaagtga aaaaagttgg
    18961 tgaaaatgct aaaattgcaa tccgtaatat ccgccgcgat gctatggatg atgctaaaaa
    19021 gcaagaaaaa gcaaaagaaa tcactgaaga tgagttaaaa acacttgaga aagatatcca
    19081 aaaagcaacc gatgatgcta tcaaagaaat tgaccgcatg acggctgaaa aagaaaaaga
    19141 attgctctca gtgtaacagg attcctacga aaaatagacg actatagaca caaaaagata
    19201 ggtgaccatt tcagaagcgt ttggttttga tttgtcccta tctttttaaa gaaagaaaaa
    19261 agatatgaat gatttactag caacagtcat tactgggctt attaaagaag aaaacgctaa
    19321 tgactatttt atccacaaag aagggtttac ctttaccttg tctaaagcag aaggagaacg
    19381 ccagattggt gatatggtca caggctttgc ctatacagac atagagcaaa aggcacgtct
    19441 cacaaccaaa gagatccgtt caacacggac aagttatggc tggggggaag tgacagaggt
    19501 tcgtcgtgac ctaggcgttt ttgtcgatac aggaattcca aataaagaaa ttgtggtttc
    19561 tttggacgtg ttgcctgaga tgaaagaact atggcctaaa aaaggggata aactttacat
    19621 tcgtttggat gtggataaaa aagaccgtat ttggggactt ccagcagagc ctgaggtctt
    19681 tcaaaagatg gctagccctg cttacaataa catgcaaaat caacattggc cagcaattgt
    19741 ttaccgccta aaattaacag gaacgtttgt ttacctgcct gaaaacaaca tgttgggctt
    19801 tattcactca agtgaacgct acgcagaacc gcgcttaggt caggttttag atgcccgtgt
    19861 gattgggttt agagaggtcg atcgtacctt gaatttatcg ttgaaaccac gttcttttga
    19921 gatgttggag aatgacgctc agatgattgt tacttatctg gaagccaatg gtggtttcat
    19981 gactttaaat gacaaatcaa gtccagaaga gattaaagca agctttggta tttcaaaagg
    20041 ccagtttaaa aaagccttgg gtggattgat gaaagctaaa cgtatcaaac aagacgccac
    20101 aggaactgaa ttaataggat aaaaatgctt tgccactggc aaagtttttt gttacaatga
    20161 agaccattaa gtgaagaaaa aggggatata gagaatggaa agagccattt ttgcaggagg
    20221 ttgtttctgg tgtatggtgc aaccttttga ggagcaagca ggtattttgt cagtcagaag
    20281 tggctacaca ggtgggcatc tcccaaatcc tagctatgaa caagtttgtg ccaaaacaac
    20341 aggacataca gaagctgttg aaattatttt tgaccctaag caaatcgctt ataaagattt
    20401 ggtagagctc tattggacgc agacggatcc aacagacgcc tttgggcaat ttgaagatcg
    20461 tggggacaac taccgtcctg tcatttacta cacaacggaa agacaaaaag aaattgcaga
    20521 gcaatcaaaa gcaaacttgc aagcttcagg acgttttgac caacccattg tcaccactat
    20581 tgaaccagca gagccatttt atctcgcaga ggattatcac caaggatttt ataaaaagaa
    20641 tcccaagcgg tatgcacaaa gcagtgctat tcgtcatcag tttttagagg agaattggtc
    20701 atgagaaaat cattttacag ctggctgatg acacaacgta accctaaatc aaatgaacct
    20761 gtggcgattt tagcagattt ggtgtttgat gacaccactt ttccaaagca taccaatgat
    20821 tttgaactca ttagtcggta tctagaagat caagctagtt tttcctttaa tttaggtcaa
    20881 tttgatgaaa tctgggaaga ttatctagca cattaatacg tggataaaaa agagtcatat
    20941 cgactctttt gaagggttat cacgttatta ttacaaaatg acatcacttt ctttcaaaaa
    21001 aatgacaagc tacttttttt cttaaaaata tgctatgata tagcttagaa aaaaataaaa
    21061 aggaagcaga gatgattatt actaaaaaga gcttatttgt gacaagtgtc gctttgtcgt
    21121 tagtaccttt ggcgacagcg caggcacaag agtggatacc acgatcggtt acagaaatca
    21181 agtctgaact cgtcctagtt gataatgttt ttacttatac tgtaaaatac ggtgacactt
    21241 taagcacaat tgctgaagca atggggattg atgtgcatgt cttaggagat attaatcata
    21301 ttgctaatat tgacctaatt tttccagaca cgatcctaac agcaaactac aatcaacacg
    21361 gtcaggcaac gaatttgacg gttcaagcac ctgcttctag tccagctagc gttagtcatg
    21421 tacctagcag tgagccatta ccccaagcat ctgccacctc tcaaccgact gttcctatgg
    21481 caccacctgc gacaccatct gatgtcccaa cgacaccatt cgcatctgca aagccagata
    21541 gttctgtgac agcgtcatct gagctcacat cgtcaacgaa tgatgtttcg actgagttgt
    21601 ctagcgaatc acaaaagcag ccagaagtac cacaagaagc agttccaact cctaaagcag
    21661 ctgaaacgac tgaagtcgaa cctaagacag acatctcaga agccccaact tcagctaata
    21721 ggcctgtacc taacgagagt gcttcagaag aagtttcttc tgcggcccca gcacaagccc
    21781 cagcagaaaa agaagaaacc tctgcgccag cagcacaaaa agctgtagct gacaccacaa
    21841 gtgttgcaac ctcaaatggc ctttcttacg ctccaaacca tgcctacaat ccaatgaatg
    21901 cagggcttca accacaaaca gcagccttca aagaagaagt ggcttctgcc tttggtatta
    21961 cgtcatttag tggttaccgt ccaggtgatc caggagatca tggtaaaggt ttggccattg
    22021 attttatggt gcctgaaaat tctgctcttg gtgatcaagt tgctcaatat gccattgacc
    22081 atatggcaga gcgtggtatt tcatacgtta tttggaaaca gcgattctat gcgccatttg
    22141 caagtattta cggaccagcc tacacatgga accccatgcc agatcgcggc agtattacag
    22201 aaaaccatta tgatcatgtt catgtctcct ttaatgctta attcatgcta ttaaaaaaac
    22261 tcacgtttag gcgtgagttt tttgacaatt ctgacagagt aagccctata agaggctgag
    22321 atacgctttt aatacctgtt gtttttctca ccctttagac agttttaacg ttatgtctaa
    22381 aagagatggt ttttattagc gcaaatatgg gtttaggggt aaaataaagg taattaacct
    22441 gatatgatca tgataaaggt agaagaatac ctattatttc gtgacaactg agcaatctgc
    22501 cttacctttg gagtgatgat atcactttgc ttgactattc aaggaggtct tgaaatgtat
    22561 tatactagtg gtaattacga agcttttgca acacctcgaa aacctgaagg ggtagatcag
    22621 aaatcagctt atattgttgg tactggttta gctggtttag cagcagctgt tttccttatt
    22681 cgcgatgggc atatggctgg ggaacgcatt catctgtttg aggaattgcc tttagcaggt
    22741 ggttctttag atggtattga aaagcctcat cttggttttg tgacccgtgg tggtcgtgag
    22801 atggaaaatc attttgagtg tatgtgggac atgtatcggt ctattccctc actggaaatt
    22861 cccggtgcgt cttatttaga tgaattttat tggttggata aggatgatcc taactcatcc
    22921 aactgtcgtt tgattcacaa gagaggaaat cgtgtggatg atgacggcca gtatacgctc
    22981 ggtaaacagt caaaagaatt aatccattta atcatgaaga cagaagaatc tctaggagac
    23041 caaaccattg aagagttctt ctcagaagat ttctttaaga gtaatttttg ggtgtattgg
    23101 gcaaccatgt ttgcttttga aaaatggcat tctgctgtag aaatgcgacg ctatgcgatg
    23161 aggtttatcc accatattga tggtttgcca gatttcacct ccctcaagtt caacaaatat
    23221 aaccaatatg actctatggt caaaccgatt attgcttacc tagaatcaca cgacgttgac
    23281 atccaatttg acacaaaagt cactgatatt caggtggagc aaacagctgg taaaaaggta
    23341 gcaaaaacca tccatatgac ggtgtctggg gaggctaagg cgattgagct aacacctgat
    23401 gatttggttt ttgtgaccaa tggttctatt actgaaagca gcacatacgg tagtcatcac
    23461 gaagtggcta agccaaccaa agcgttaggt ggttcttgga atttatggga aaatctagct
    23521 gctcaatcag atgattttgg tcatcctaaa gtgttttacc aggacttgcc tgctgaaagc
    23581 tggtttgtgt ctgctacagc aaccataaaa cacccagcta tcgagcctta tatagaacgt
    23641 ttgacccacc gtgacttgca cgatggcaaa gtgaacactg gcggcatcat cactattaca
    23701 gattctaact ggatgatgag ctttgccatt caccgtcaac ctcattttaa agaacaaaaa
    23761 gaaaatgaga ccactgtctg gatttacggt ctttattcca atagtgaggg caattacgtc
    23821 cacaagaaaa ttgaggagtg tacaggtcaa gaaatcacag aagaatggtt gtaccacctt
    23881 ggggtacctg ttgataaaat caaggactta gcgagtcagg actatatcaa tacagttcct
    23941 gtttacatgc cttatattac gagttacttt atgccacgcg tcaaaggaga ccgtccgaaa
    24001 gttatcccag atggttcagt caacttggcc tttattggta actttgcgga atctccatct
    24061 cgagatacgg tctttacgac tgagtattct attcgtactg ccatggaagc agtgtatagc
    24121 ttcttgaatg tggaacgagg catcccagaa gtctttaatt cagcctatga tattcgtgaa
    24181 ttgctcaaag ccttttatta ccttaatgat aaaaaggcaa tcaaggatat ggatttgcca
    24241 attcctgcac tgattgagaa aatcggacat aaaaaaatca aggatacctt tatcgaagaa
    24301 ttgctcaaag atgctaatct tatgtaacat gccttagagt agttaaagct gataagttta
    24361 ggcttatcag cttttttgat gatttataga aaagtgataa aggaaaagtc tgacgtgaac
    24421 gtcacataag aatttaaaat ttgttataat gtaagcaata aagatgaaag aaagagggac
    24481 tctatttgca agagtattct attgacatta ccttaaccca tcctgatgat gttttagctc
    24541 tttttggtag caacgagcgt catttgaagc taatagaagc tcatttagga gttattgttc
    24601 acgcaagaac cgagcgagtc caagtgattg gtgatgatga agaagctgtg gaattggctc
    24661 gattgaccat caaagcccta ctggttctag tgggtcgtgg catggtggtc aacacatcag
    24721 atgtggtgac agctttatct atggcagaat ctcatcagat tgaccaattt atggcgcttt
    24781 atgaagaaga aatcattaaa gataactatg gtaaggcaat acgagtcaaa acattaggtc
    24841 aaaaaaccta tgttgatagt gtcaaacgtc atgatgtggt ttttggtgta ggacctgcag
    24901 ggacaggtaa aaccttctta gctgttacgc ttgcagtcac tgctctgaaa agaggacagg
    24961 taaagcgtat tattttgacg cgtcctgcgg tagaagctgg cgaaagccta ggttttttac
    25021 caggcgattt gaaagaaaag gtggatcctt acctcagacc tgtttacgat gccctttatc
    25081 acattttagg caaggaacaa accacacgcc tgatggaacg agatgtgatt gagattgctc
    25141 cgttagctta tatgcgaggt cgtactctgg atgacgcttt tgttatctta gatgaggctc
    25201 aaaacacgac catcatgcaa atgaagatgt ttttgacccg tcttggtttt aattctaaaa
    25261 tgattgtcaa tggagatacg agtcagattg acctccctcg aaatgtcaag tctggtttga
    25321 ttgatgctac tcagaaatta caaggcatta aacagattga ttttgtctat ttctctgcta
    25381 aggatgttgt ccgacatcct gttgtggctg atattatcaa ggcttatgaa acgtcctcag
    25441 aggagatgaa ggacttacta aaacctaagg ctagtgacgt tgaagctgat taccagccag
    25501 gcttgacaaa ataccctgtg atcggtcaag agcactaaga cttttacgat gatgtttaat
    25561 atggcctttt taaggaggat tctatggatg atttaaccaa agctattatg gcagatgagg
    25621 ctaatctctc ctataccgaa agaggtattt ttcctttata tgatgctcct caaacagcta
    25681 ggattattat tgttggccaa gctcctggaa tagtagctca aggaaccaaa ctttactgga
    25741 atgatcgtag tggcatccgc ttacgagact ggctaggtgt ggacaatgac accttttacc
    25801 actcaggatt gtttggcatt atccctatgg atttctatta tcctggtaag ggaaaatccg
    25861 gtgacttacc acctagagaa ggttttgcgg ctaagtggca cccgccatta agagcattga
    25921 tgccagaagt tgaattgacg attttggttg gtcgctatgc tcaggacttt taccttggta
    25981 acaaggctta caaaacctta actgaaacag tccgtcactt tgaggattac ttgccagact
    26041 attttccact tgttcatcct tctccaagaa accaattgtg gttagctaag aacccctggt
    26101 ttgagcagga tttattacct atcttgcaaa aacgtgtgga ggcaattcta accaaatagg
    26161 ccctgattta cctagcattc ccatttttaa ggggcttgtg gtataatggg taaataacaa
    26221 atgctgattg aaaggataag ggaaattatc tgtcagataa taatgggtgc ccaacatacc
    26281 aaatgaggtg ggcagccctt ccctaacaat taaccttatg tatatcgaga tgattgacga
    26341 aacgggacaa gtttcgcaag agattatgga gcaaacactt gatttgctca attttgctgc
    26401 tcaaaagacg ggcaaagaag aaaaagaaat gtctgtgacc tttgtgacca atgaaagaag
    26461 tcatgaactc aacttagaat accgagatac tgatcgtcca acagatgtga tttctctaga
    26521 atataagcca gaaacgccta ttttatttag tcaagaggat ttggctgctg atcctagttt
    26581 ggcagagatg atggcagagt ttgatgctta tattggcgaa ttgtttattt ctattgacaa
    26641 ggcgcgtgag cagtcccaag aatatgggca ctcttttgag cgtgaaatgg gatttttggc
    26701 tgttcatgga ttcttacata ttaatgggta tgatcactac acccttgaag aagaaaaaga
    26761 gatgtttacc ttacaggaag agattttgac tgcttatggc cttacacgac aataatacca
    26821 ccaaacggaa atggaaaaac agaaccatta cctcaagctt ggagtttgcc ttgacagggg
    26881 ttttcacagc ttttaaggaa gaacgcaatc tcagaagcca ccttttgtct gcctgtttag
    26941 cttgtgttgc tggtttattt tttagcattt cagccatcga atggttattt ttacttctag
    27001 ccattttttt ggtcattacc ttagaaattg tcaattctgc tattgaaaat gtagttgatt
    27061 tggctagtga ctatcacttt tctatgctag ctaaaaatgc caaggatatg gcagcaggtg
    27121 ctgttttgat gatttctggc tatgctgtct tgacaggact tattattttt attcctaaaa
    27181 tttggaatat tttcgttcat taaaaagaaa ggaatgggct atcctatgtg atgatggcat
    27241 aggagaataa ggaaaggaca agacggttaa gcttagtgac aagcttgatc tgaagcccta
    27301 ccgttaaagc ccgtaattat ctatgtttaa atcaggcttt gtagccattc ttggtcgtcc
    27361 aaatgttggc aaatccacct ttttaaatca cgtcatgggg caaaaaattg ccatcatgag
    27421 tgacaaggct cagaccaccc gtaataaaat tatgggcatt tacaccacag aaacagaaca
    27481 aattgtcttt attgatacgc caggtattca taaaccaaag accgcccttg gtgattttat
    27541 ggttgaatct gcttatagta ctttacgtga agttgagacg gttcttttca tggttcctgc
    27601 cgatgaaaag cgtggtaagg gtgacgacat gattatcgag cggctaaaag cagctaagat
    27661 tcccgttatt ttagtcatca acaaaattga taaggttcat ccagaccaac ttttggaaca
    27721 gattgatgac ttccatagcc aaatggattt taaagaagtg gtcccaattt ctgccctaga
    27781 aggtaataat gtgccaactt tgatcaagtt attaactgat aatcttgaag aaggtttcca
    27841 atattttcca gaagatcaga ttactgatca tccagaacgt ttccttgtgt cagaaatggt
    27901 tcgtgagaag gtactgcatt tgacgcaaca agaggttcca cattccgtag ctgttgttgt
    27961 cgaatccatg aagcgagatg aagagactga taaagtgcat atccgtgcaa ccattatggt
    28021 ggagcgcgat agccaaaaag gcatcatcat tggaaaacaa ggagccatgc tcaaaaaaat
    28081 cggaaaaatg gcgcgccgtg atattgaact catgttaggc gacaaggtct acttagaaac
    28141 gtgggtcaaa gtcaagaaaa actggcggga taaaaagctt gatttagctg attttggcta
    28201 taatgagaaa gaatactaac atagtaaagc gagatcatat gccacaagac tacatttctt
    28261 atatccgctc caaagttggg catgataaga ttattcttaa ctttgctggt gggattttga
    28321 ccaatgatga cggcaaggtg ctgatgcagc tgcgtggtga taagaaaacc tggactattc
    28381 ctggtggcac tatggaactg ggtgagagct ctttagagac ttgcaaacgt gagttcttag
    28441 aggaaaccgg aattgaggtt gaagctgttc gcttactgaa tgtttacact cattttgagg
    28501 aagtttatcc caacggtgat gctgttcaga ctattgtctt tatctatgaa ctaacggctg
    28561 tttctgatat ggctattgat aactttcata atgaggaaac gctcaagtta caatttttct
    28621 ctcatgagga gatagcagag ttagagagtg tctcagccaa acatcgcctg atgttagagg
    28681 aatattttag tgatagcttt gctatggggc attaagaact ctctaggaca gttggagtat
    28741 ttttggagat tggcttgtta aaaaaatttt tgaaagacga tattcgagag cttatgctct
    28801 ctttttttgc ttccaatttt tctgattaag tctgaataat tttgttaaat gttaacagga
    28861 ttttctttcc aattgatact agcagacatc aaacatttgt tttagagtta tgacgaattg
    28921 ccacctagcc atgcatgact taggcaagtt gaacctaact gtgacaatag acttgggagg
    28981 ggtgacaaga atcatttcct aaaagaattg atgaagtgcc tatccattat tcgaattgta
    29041 aagttcgtct aagtaaagtt gaatttggtc tcgaatggac cttaatgatt tatgacttgt
    29101 tgtgtcaata acaccaaaaa ctcgataatg atttttaaat atttcctcgt aattaatatg
    29161 atttccgatt agaataatat gagcatgagg ataacgcata cgtatttcgt ttagaaggtc
    29221 atatacttgc ttagatttaa aaaagtatga tttatgataa aataaacctg acatttgtat
    29281 ttataatcta agtttttccc actaataatt tgagttttta gaaagtatct cttgaggtaa
    29341 tagttaatat agatagatat catatatcct aaaagagaac gatgtcttgt aagtattttc
    29401 gaagactata atattaagtt cggagctcgt attcataaag gattcggagt atgttttgac
    29461 acacttgata gcttatttga ctaatattca aaaactctac tcttgtgttt acacaacatt
    29521 attgacagt
//
LOCUS       DAUGJR010000021        28659 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUGJR010000021 DAUGJR010000000
VERSION     DAUGJR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28659
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.021"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            227..1633
                     /locus_tag="VH800_000968"
     CDS             227..1633
                     /locus_tag="VH800_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEQ8362046.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LEPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNCFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
     gene            complement(1701..2611)
                     /locus_tag="VH800_000969"
                     /pseudo
     CDS             complement(1701..2611)
                     /locus_tag="VH800_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            2732..3916
                     /locus_tag="VH800_000970"
     CDS             2732..3916
                     /locus_tag="VH800_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8362047.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            3928..4587
                     /locus_tag="VH800_000971"
     CDS             3928..4587
                     /locus_tag="VH800_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8362048.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANQA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            4590..5237
                     /locus_tag="VH800_000972"
     CDS             4590..5237
                     /locus_tag="VH800_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8362049.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(5359..6039)
                     /locus_tag="VH800_000973"
     CDS             complement(5359..6039)
                     /locus_tag="VH800_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8362050.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            6213..6578
                     /locus_tag="VH800_000974"
     CDS             6213..6578
                     /locus_tag="VH800_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8362051.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            6615..7634
                     /locus_tag="VH800_000975"
     CDS             6615..7634
                     /locus_tag="VH800_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEQ8362052.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            8089..8409
                     /locus_tag="VH800_000976"
     CDS             8089..8409
                     /locus_tag="VH800_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362053.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            8399..10420
                     /locus_tag="VH800_000977"
     CDS             8399..10420
                     /locus_tag="VH800_000977"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEQ8362054.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQSKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANNHFYHQLKQHKGLLKQHKGLFIEEVYHTEFEY
                     GLVLFWQAQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQS
                     QKILAQLQVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGD
                     MFYLDSYDVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTF
                     FGMMVADLGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGF
                     DLPVALLSTKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFI
                     LLGLLLFILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGI
                     SSYLSDLVSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLS
                     MLSGYVHGARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            10422..10901
                     /locus_tag="VH800_000978"
     CDS             10422..10901
                     /locus_tag="VH800_000978"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEQ8362055.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            10969..11553
                     /locus_tag="VH800_000979"
     CDS             10969..11553
                     /locus_tag="VH800_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEQ8362056.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            11569..12567
                     /locus_tag="VH800_000980"
     CDS             11569..12567
                     /locus_tag="VH800_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEQ8362057.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            12564..12884
                     /locus_tag="VH800_000981"
     CDS             12564..12884
                     /locus_tag="VH800_000981"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEQ8362058.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEVLTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            13085..14860
                     /locus_tag="VH800_000982"
     CDS             13085..14860
                     /locus_tag="VH800_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEQ8362059.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            14861..16276
                     /locus_tag="VH800_000983"
     CDS             14861..16276
                     /locus_tag="VH800_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEQ8362060.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            16321..16947
                     /locus_tag="VH800_000984"
     CDS             16321..16947
                     /locus_tag="VH800_000984"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEQ8362061.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLKETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(17067..18329)
                     /locus_tag="VH800_000985"
     CDS             complement(17067..18329)
                     /locus_tag="VH800_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEQ8362062.1"
                     /translation="MADFNFDIDQIADNAVIKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKITRA"
     gene            complement(18342..19220)
                     /locus_tag="VH800_000986"
     CDS             complement(18342..19220)
                     /locus_tag="VH800_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362063.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPQIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHDANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            19658..20950
                     /locus_tag="VH800_000987"
     CDS             19658..20950
                     /locus_tag="VH800_000987"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEQ8362064.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLGFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            21277..22320
                     /locus_tag="VH800_000988"
     CDS             21277..22320
                     /locus_tag="VH800_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8362065.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIETAK
                     KAIIEGTITVPEN"
     gene            22493..23032
                     /gene="nusG"
                     /locus_tag="VH800_000989"
     CDS             22493..23032
                     /gene="nusG"
                     /locus_tag="VH800_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEQ8362066.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            23403..24758
                     /gene="nga"
                     /locus_tag="VH800_000990"
     CDS             23403..24758
                     /gene="nga"
                     /locus_tag="VH800_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEQ8362067.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFVSPM
                     RIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            24763..25248
                     /locus_tag="VH800_000991"
     CDS             24763..25248
                     /locus_tag="VH800_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEQ8362068.1"
                     /translation="MYKVPKSLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMVHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            25272..26987
                     /gene="slo"
                     /locus_tag="VH800_000992"
     CDS             25272..26987
                     /gene="slo"
                     /locus_tag="VH800_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEQ8362069.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRS
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            27242..27673
                     /locus_tag="VH800_000993"
     CDS             27242..27673
                     /locus_tag="VH800_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362070.1"
                     /translation="MKQQSYQPLRFVYLLVALFAAMLLIARPVMADGENNDPANAAYY
                     KGKSAGEEAGKTAGKEASWTDLTPTNPTIPEPPSDIRETTNKQHYKDGYTDGYRDGYN
                     EGWKSQHPVLTPVKVIWDLISHWLQQFFPNNQATTTVQSMS"
     gene            complement(27859..28095)
                     /locus_tag="VH800_000994"
     CDS             complement(27859..28095)
                     /locus_tag="VH800_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362071.1"
                     /translation="MKKKLSLFMIATAAVVSLSLATPENQTVSANDTQVTCVGCPDCG
                     PKWSCCPLTCMRDLLRGWGKSAAYYCTWGYYYSE"
     gene            complement(28505..>28659)
                     /locus_tag="VH800_000995"
     CDS             complement(28505..>28659)
                     /locus_tag="VH800_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362072.1"
                     /translation="SLFMIATAAVAGLSLATLGSHQTVSANDASYSNGFYGHTGPDSW
                     LLYTVW"
BASE COUNT         8844 a         5045 c         6110 g         8660 t
ORIGIN      
        1 agtgaagcgc cattcttttt gctataaata agggttatgg aagcaataaa aaaatcatag
       61 ttgtttatga aaacgctgtc ataataaaaa ggggacaaaa gtgttttttg tggatttaaa
      121 cttattgata actaaatgaa ctaaagaaac gcttattaat attatcgaca ggttactggt
      181 caaaagaaca aaagtgcttt tggacaatgt gaaaggaatt gacaacatga ataacatcaa
      241 aaccaaaaaa aggtttatgg atcgctatat tgatggcttt atgaaatgga tgccagaatc
      301 gctttttatc tgttttattt taaccttttt agtcgttact atgtctgtgt tgatgacgga
      361 tagtcccttt attggtacgg aaaagacggg cgggattatc tatggctggg taaatggttt
      421 ttgggggctg ttgtcctttg ccatgcagat gactatttta cttgcgacag ggaatgctgt
      481 agcgagttct ccacctgctc ataagatgtt taagtccctt gccaaactgc ctcaaaccag
      541 gactcagatt tttatctttt ccattgtagt aggctctatc tttggctttt tacactgggg
      601 tcttggtatg atggttgcta ttgtgtttgg gaaagagttg cttgttcagg ctaggcaaaa
      661 agggattaag gtgcatacgc ctttgtttgt tgctacttta ttttttacct ttttaccagc
      721 tacttctggt ctatctggtg ctgcggtgct ttattcggct actccagatt atttgcgaaa
      781 tagtgtcgca gatgcttata aacaggttgt tcctgaaagt gttcctctga cagaatcagt
      841 tttgaatctt ccatttatca gtcttttagt ggtgtgtatg ctggaaccgc tttgctttgc
      901 tttattggcg cacccaaaag atgaaactaa aatcatggaa cttgatgatg agatctatca
      961 ccatagtctt gataccgctt cacatgttgt tattgcaaga aacacacctg ctgaaaagat
     1021 gaacgcatct cgcttagtga tgtatcttgt tggtggggcc attgttagct atagccttta
     1081 tcatttttcg gtggtgggct tgtctggtct agatctcaat tgttttaact ttttattttt
     1141 aggcttaggc ttgcttcttt gtggtcaaca aggaccagaa tattatggtt ccttattcaa
     1201 agatggggtc atgtcatctt ggggcttggt gcttcagttt ccattttacg ctggtatttt
     1261 tggaatcatt caaagtacag gtttaggatt agagatttcc catttctttg tcgctatttc
     1321 aaatgggaca acatggccgg tctttgctta tctttactcg gctttgctga atattgcggt
     1381 accatcagga ggctcaaaat ttgtgattga agctccctat atcgtccctg caactatcga
     1441 agttggtaat gacttaggta agattttgca ggcttatcaa ttaggagatg ccacaacaaa
     1501 cttgatagtt cctttttggg ccttatctta cctctcaaac ttcaaactaa aattcaatca
     1561 aattgtggct tatactattc cttgtgtctt ggtggtcaca ggtattgcca tcatttacct
     1621 atttgtattt taggaaataa ctacatgaaa cgcttgggat tgtttccttc aggcgttttt
     1681 ttaaggtctg agtccagcaa ttagaagcgc tggttcatga aataatctaa gatggtgtgc
     1741 ttgatataat gttttaaatg gcttgttttg ttgtgcttga gagaggctag aacaacttcc
     1801 cattttggat gttcggtcag ttggacctcc actaaaccgt ccatatgagc aaaatgagta
     1861 ataggtcttg gtaggattgt taggtaagag gaatagcgcg tgcaatttaa taaaaaatcc
     1921 cacgaggcag aataacattt gactacagga agactatttg cttcttcaaa taaggtggta
     1981 agctgatgat taatcataaa ggttttatca aaagttacta agttttgacg atgtaatgct
     2041 ttgatagaga tgttaggatt actatcaaac gtctcttgaa aggttttgtg actcatataa
     2101 aggcagagtt gatctcttag gagaatgtcg atatcagcaa tagtagcatc tagtgtagtg
     2161 ggtgttaata aaatcgcaaa atcgacttct tttagaaaca gtttttttgc agttcataag
     2221 cacccgtttc tacaatatga aatttaactt cgggattttc ttcgatgagt tttggaatga
     2281 gctcagaaaa aacaatgcca gagatgagtt gaggaatacc gattgaaatt tctcctttgt
     2341 attttttgga ttcactccgc aaatcagcca ttaattgctc atgtgatgcg ataaccacct
     2401 tagcattttc aaaaaagcgt tcgccgactg aagttagtcc aactagacgc cctttttgac
     2461 gctggaataa aacgactcct tcttcttttt cgatagtctt gatataacta ctaagggcgg
     2521 gttgcgaaat atgacttttt tgggctgctt tggttaagtt aaagtcacaa ttaacaatct
     2581 caataaaata agccaagctt gagatattca tattttcctc tttcgataac gtttagttat
     2641 agcatatata aaaaaacgat atttgtttat tatagttcac attatataat aaaaatgtaa
     2701 gcgtttcaat aatgaaaaag gagaagtttc tatgactaaa gaagtggtga tcacatctgc
     2761 ttatcgtacc ccgataggaa attttggagg agtctttaaa tctttatcag ccgtagattt
     2821 gggggtgaca gttgttacaa aaattttagc tgataccggt cttaaaagtg atgccattga
     2881 tgaagtgatc tttgggaatg tgttacatgc aggtctgggt caaaatgttg cccggcaagt
     2941 agcgctaaat gcggggcttt cttatgatac ccctgctttt acgattgata tggtctgtgg
     3001 ttctggctta aaagcagttg agttaggtgc tcaaaagatt caaacgggca acgctgatat
     3061 tgttttagtt ggtggtaccg aaaacatgag tcaagcacct tacgttttac aaggccaacg
     3121 ttggggatct cgtatgggag atagtaaagt agtagatacc atgcttaaag atgggttgag
     3181 tgatgctttt gcaggttatc acatgggtat aacagccgaa aatattgtgc aacagtatgg
     3241 actgaccaga gaagaacaag atgcctttgc agctgatagc caacgtaaag cccaacttgc
     3301 catagaaaaa ggtcgtttca aagaagagat tgcacctgtc actattcctc agcgtaaagg
     3361 tgaaccttta ctcgttgatc aagatgaata ccctaaattt ggaacgacag tggataagtt
     3421 agcaaagtta cgccctgctt ttatcaaaga tgaggggaca gtaactgctg gtaatgcttc
     3481 aggaatcaat gatggagcag cggcaatttt attgatgagt aaagaaaaag ctgaagaatt
     3541 agggctccct attttagcta aaatcactag ttatgcaagt gcaggtgtag acccaagtat
     3601 tatgggctgc ggaccaatac ctgctacgaa aaaggctctt gcaaaggctc agctgacaat
     3661 tgatgacatt gatttgattg aagcaaacga agcttttgct gctcaggctt tagcggtttc
     3721 acgagacctt ggttttgaca atgaaaaagt taatgtcaat ggaggagcta ttgctttggg
     3781 tcacccgatt ggagcatcag gtgctcgtat tttagtcacc ttattagcag aaatggctaa
     3841 gcgtgatgtg agacatggct tagcaacgct ttgtattggt ggtggccaag gtcaaagtat
     3901 catcgtaaca agatagaagg taaccgtatg aaagagaata aaagaatagc aatagcagaa
     3961 gctatcagtc atattaaaga tggtgacacg attatggtcg gtggttttat ggctaatgga
     4021 acaccagaag cgttaattga tgcactggtt gacaaaggca caaaagactt aaccttgatc
     4081 tgtaatgatg ctggttttgt tgatcgcggt gttggaaaaa tggtggctaa tcatcaattc
     4141 aaaaccattt atgcaacaca tattggatta aataaagaag ctgggcgcca aatgactgcc
     4201 ggtgaaacga cgattgagct cattcctcaa ggaaccttcg ccgaaaaaat tcgcatcgga
     4261 gcttatggca ttggtggctt ttacacgcca acaggggtag gaaccttagt ggcagaaggc
     4321 aaggaaacaa aaaccatcaa gggaaaaacc tatctcttag aatacccatt tgaggcagat
     4381 gtcgccttga tatttgctaa tcaagctgat gaaatgggaa atttacagta tagtggttct
     4441 gaaaataatt ttaatcaatt gatggcagct tgtgcaaaaa caacaattgt tcaggcgcga
     4501 gaaatagtac cagtcggcac catacaacca gaatgcgttc atacaccaca tatttttgta
     4561 gattacattg ttaaagaagg agtatagtta tggcggttgc attaagtaaa gaagagattc
     4621 aaaatcgtat tgcaaagcgt gtggccaaag aattagaaga tggtactttg gtaaatttag
     4681 gtattggtct accaaccaaa gtagcaaatt ttgtgcctga agaaatgaca gtgtattttc
     4741 aatctgaaaa tgggtttatt ggactaggtc ctaagtcaga tgatccgaat tcgactatcg
     4801 ttaatgcagg aggacagcct gtgacggttt atccaggagc cgctttcttt aatagtgcag
     4861 attcttttgg cattatacgt ggtggtcatg ttgatttgac cgtcttgggt gctttagaaa
     4921 ttgcagaaaa tggagatatc gccaattacc tgattccagg caaaatggtt cctggtatgg
     4981 gaggagcgat ggatttatta gttggtgcta aaaaagtcat cgtagctatg gagcatacca
     5041 ataaaggaaa gcataagctc ctaaaagaat gtaccttacc tttaacagca aaaggtgtgg
     5101 ttgaccttat tatcacagaa atgggtgtgt ttaaagtaac gccagatggt atccaagtaa
     5161 ttgaaatcag tgaagggttt acttttgatg aggttcaagc tgcgacaggt gtacctctaa
     5221 gcatagctga aggttaatga ccagtagcct tttcttgcca taaaggcata ttgagtaaaa
     5281 aaaacgtcag tcatcggtat atcagagatt gtgatgctta tctgaaatac ttttaactgg
     5341 cgttttatgg tgatttggtt attgatcggc ttcaattttt ttaaggtagc ggtaaacact
     5401 tggttcggaa atacatagaa tatcagcgac ttttgagacg gctcctttta gctgaaagac
     5461 ccctttttca taaagcttgg caacaatgtc tattttgaca tcttggctaa gatgtacatt
     5521 gtgtctcagt aacgagggat caataatttg accgataata tcttggatgt tagaggttaa
     5581 aatttcaaca gcttcttctg gctggggtgt gactgtttta ggctctttag cagttgggat
     5641 gaaatgttct aaattgagat tgacaagttt taagaggtcc ctagctactc cttgataggc
     5701 tgaaatatct aagttaatac atagcattcc ctcgagatta ccctttttat ctttaataaa
     5761 aaaagtagat ccccgaactt ctttgtgctg aggactaacg attgctttgt aattggtcac
     5821 aaaatctttt tccttataga ctttattagt aatcaaatca agagcaaagg tggtgagagg
     5881 agactgttta gaccgtccac tgatatgact attaacgagt tctccaatat agatatcatt
     5941 tttatcaatc acatgtaaaa taatttcata gttatcacct aagacatcgt gaagaaatgt
     6001 gataaccgtt ttccagtagt ttagcgtttc tttatccatg tcaaacttcc tatatctatc
     6061 ttcttattta caaatatagt aatacatttt agactaaaaa acaattgcca atcaccttaa
     6121 taataatttt ttatcaaaaa gagaatttat tattgactgt gaatgcggtt tcctgtaaaa
     6181 tttaactata ttatcaatga ggaggttcgt atatgaagag ctacccagaa ccaatgggcc
     6241 cttattcaac ttatacgatt gaaggacatt ttctatacac cgcaggccaa ttacccctta
     6301 atccagtgac aggtcaattg tcagatggtt ttgaggcaca gtgtcgccag gtttttgtta
     6361 atttacaatc tattttggca gagcaaaagt tggacttgaa tcatatctat aagctaaatg
     6421 tgtatttaac agatgtgacc aatgtggaaa tattaaatca tgtcatgact gatttgtttg
     6481 aagagcccta ccctgttcgg acagcggttc aagtgtcggc gcttcctttg caagctttga
     6541 ttgaagtcga agctgtcgcc agagtgaagc agttatagtg tcttatgtaa tgagatagat
     6601 tggtggaata gattatggat attattattg gaacaagtct tttgattctt gttttagcta
     6661 tttttagctt gtttaactat aaggctcctc atggtgccaa ggcaatggga gctttggctt
     6721 cggcagcttg tgcctctttt ttagttgaag cctttcaaga ttcttttttt ggtaaggttt
     6781 taggctttca gtttctaagt gaagtaggcg gagcaaatgg ctcattatca ggggtagctg
     6841 ctgctatctt ggttgccatt gcaattggtg tgtctccagg ttatgccgtt ttgattggtt
     6901 tgtcagtttc aggaacgggt attatcccag gttttgtggc tgggtatgtg gtatcttttt
     6961 taatcaagtg gatggaaaaa aatattcctg gtgggcttga tttaatctcg attattattg
     7021 tcggtgcacc attaactcgt ttcttggcgc agttaattac gccagtgatc aatagtactt
     7081 tattgactat tggagacatc ctgacctcaa gtgctaatag caaccctatt atcatgggaa
     7141 tgatactagg cggtacgatt gttgttgtag caacagctcc gctgtcatca atggctttga
     7201 cagccatgct tggtctaaca ggtattccga tggctatagg tgccttatct gtctttggct
     7261 cttcttttat gaatggtgtt cttttttacc gattaaaatt gggtgaaaga aaagacaata
     7321 ttgcttttgc tattgaacca ctaacgcagg cagatgtgac gtcagccaat cccattccga
     7381 tttatgtgac taattttgtt ggtggtgctg catgtggtgt tttgatcgcc ctaatgaaat
     7441 tggttaatga tacgccaggg acagctactc cgattgccgg ttttgcggtg atgtttgcct
     7501 ataatcctgt cgctaaagtg ttgataacag cccttggatg tattattatc agcttaattg
     7561 tgggttatat tggaggttct gtctttaaaa attaccgttt agtaacaaaa caagaattac
     7621 aagcgagaaa ctaataaaca tctttttgac aggactttta acaagatagc agttatactg
     7681 ttatcacatt ggcttggcta ttggctggta aaggtacctt accgtcaact agatcaaggt
     7741 tactaaatgc ctaaagaagt ataagataac acacgaaaga cagcaataca aagctttaga
     7801 gttctgtgtc atcttactgc tttgacaggt ttttagctaa cctttttctg aactaagcca
     7861 ttgtttttat ggatagaatt gaaagcgctt aacttaaaga tgctgttcgt ttaattaagc
     7921 cattatccta tctcaaaaaa gctgttagta gataggttag agatttagct ctagcttata
     7981 ttcactggtt gattaacccc ccaaaagtag cctttcttgt agctttgttt ttaagtacct
     8041 agtgagtcaa agaattagca atagataaag ataaggagtt gatatgtgat gaatacccta
     8101 ttgtcactaa tgaatagtat cgaacaagag gctagaacaa tttatgacag ttacgatgct
     8161 aagaaaaaag ctctagctga caaaaaagaa gaagagttaa agcagctgtt ccttgagtac
     8221 gaacaagaaa ctcagctact attagaagct aaacgtgagg tgttttttga agctaatcgt
     8281 caagaacaaa aagcttcaaa aaagagatta gcgacgcaac agctagccct tcatgccatt
     8341 ttagaagagc ataagctaac cgttgttagg gagttagtgg ataaggtggt ggagacatat
     8401 ggccattagt caaatgaaaa agctggcaat ggtttttgaa aaagattatc ttgatcttgt
     8461 tttaaaaaca cttcaacaat ctcaattagt tgaagttcgt gacatgaagc aactaaaaca
     8521 ttggcaagat gcttttaaca aaggcaacgt caagttgcca caaatcgtcc aatacgatct
     8581 gacgcatcaa aaacctctac tagatgatga agctttacaa taccttttac aaagccaaca
     8641 agagttagaa aacggccttg ctagcttatc agcgttttta ccaccaatag gaaagttaac
     8701 agccttgaga caaaaaacgc catctctttc gtttaaacag ttcgaagaac gccatcgaca
     8761 acaagcagct caaacggctt tgaaaatgat gtcacaaaag atagagcgac tagagcagct
     8821 gcaaagcaaa atagaccagc taacagaata ctgtcaggag ttagaaaagt ggcgttcctt
     8881 gactgttttg cctcaggact tagcgcaatt tcattttttg tcggcaagag ttggaacgat
     8941 tcctagtaca gcaaataatc atttttatca tcagctaaag cagcacaaag gtcttttaaa
     9001 gcagcacaaa ggtcttttta ttgaggaagt ataccataca gaatttgagt acggccttgt
     9061 cttattttgg caagcacaag atacgattca tttacagaaa tatcagttta aacccttatt
     9121 atataaagaa cagttactgc catcagaaca acttcgtata aacaaagagt tactaacgaa
     9181 ttggctagct gaaaaagata gtctactaaa agagcttagg cagtctcaaa agatactggc
     9241 acagttacag gttgaaatag actatgtcct tagtcagtat caacggcagc aaactaaaaa
     9301 gcaattactc ggtacaagac atctaatagc cttagaaggg tggatagaag ctgattcggt
     9361 taaccaatta aaagggctaa tgactaagac actaggtgat atgttttatc tggatagtta
     9421 cgatgtcacg ccagacgatt gggaagatgt tcccattaag ctacgtaatc accgctacat
     9481 tgcaccgttt gaattggtta cagaaatgta cgctttgcca aaatatcaag aaaaagatcc
     9541 gacacctttt ttagctcctt tataccttac tttttttggc atgatggtag ctgatttggg
     9601 ctatggtttg ttgctatatg ctgtgacact agctgcattg gtctttttta atctccaaaa
     9661 aaccagtaaa cggttagtga ccttctttaa tattttagct atttcagtag ccatatgggg
     9721 gcttatttac ggttctttct ttggttttga cttacctgtg gcattattat caactaaaac
     9781 ggatgtgatt actattttgg ttgtttcttt gctatttggg tttgttacac ttatatttgg
     9841 gcttttgtta ggagcatggc aacaagtaag gatgaaagca tatgctacgg cctatacgtc
     9901 aagtctagct tggactttta ttttattagg tctgctgtta tttattcttg gtaagaatgt
     9961 atctggcctt gcttacttat cggttattgg taagtggctt gcattgggca atgcctttgg
    10021 gattttggtt gtttctttac taaaaagcaa aagcctttta ggtctaggta gtggattata
    10081 taatttatat ggcattagct cttacttaag tgatttggtt agctttactc gtctaatggc
    10141 attagggctt tctggagcta gtattggagc ggcttttaac atgattgttg ggatttttcc
    10201 accagtcacg cgctttacag taggtatctt tatttttatt cttttgcatg cgatcaatat
    10261 tttcttatca atgctttcag gatatgtgca tggtgctcgt cttattttcg tagagttttt
    10321 tggaaaattt tatgaaggtg gaggaaaagc tttcaatcct ttaaagttag ctgataatta
    10381 tgtcaatgtc aatgaagaaa cagatttgga ggacaattaa catggaacat ttagcacatt
    10441 attttacagc acatggtggc gttttcttcg cagccttagg aattgtttta gccgtagctc
    10501 ttagtggcat gggctcagct tatggtgtcg gtaaaggtgg tcaagcggca gctgcgctct
    10561 taaaagaaga acccgaaaaa tttacgtctg cgcttatctt gcaactgtta cccggtagtc
    10621 aaggaatcta cggctttgct attggtattt taatttggat gaaactgaca ccagaacttt
    10681 cagttaacca aggattagct tactttttgg tatctcttcc aattgctatt gttggttatt
    10741 tttcggccaa gcaccaaggc aatgtttctg tagctggtat gcaaatcttg gctaagcgcc
    10801 ctaaagactt tatgaaaggt gtcattttag cagctatggt tgaaacctat gctattcttg
    10861 cctttgtcgt ctcctttatt ctcttaaata aaattggata aggtatggtc cttatctaga
    10921 ttttaaaaaa cggtgacacc actaacacta tcaaaagggg gaaattaggt gaatgatata
    10981 acacagttaa gacaaaacgt tcttgaaaaa gcacatcaag aaggtcaaca gtgcctaaag
    11041 atagcgacag atagtcttga tactgacttt aaagagcgtc aacagcaagg actacacgat
    11101 ttaaaagcaa agcgtcaaaa agagttaaaa gctcttgaac agcaatttca ggttgcgcag
    11161 cagcaactca aaaatcaaga aagacaagct ctactagcat taaaacaaga cagtataaag
    11221 gagctatttg aagcttcttt ggagaagatg acgaactttt ctaaggaaga agaattggct
    11281 tttttgaagc aagtcttgtc taaatatcca gaacagccat tgcaagttac ttttggcgaa
    11341 aaaacagggc aaaagttcag ttcttatgat tgtgctgagc tgagattagc atttcctcaa
    11401 ttaagctata atcaagagct aattcctcag gaagcaggat ttttagtcag tttagaccaa
    11461 gtcgatgaca attatttata ccgttacctt ttagaatcag ttcttaaaga agaaagctcc
    11521 cgcatcattg atatgctttt ttcagagata taggaggttt gactagcgat gccaacattt
    11581 ctagaattaa acactactat cagtgtcaaa gaaaaagagt tattgactaa agagcaattt
    11641 gataagctat tgcaggctcc caatacaaca accttagctc gactgttgca ccagtcagtc
    11701 tatcacctaa ctgttgacga tctcaacgat ttggatcggc tagaatctat cttaatggct
    11761 gagctaacca agacctatcg ctgggctttt gcagaaaccc ctcaacctga catagtacaa
    11821 ttatttacct tgcgttacac ctatcataat gtcaaagtgt tgttaaaagc taaagctagt
    11881 caagcagatc tgagtcactt attactacca attggtgaca agcctttggt ggctttggaa
    11941 catttgatta ggacgatgac ttctgatgag tttccaaaag aggtggtaac agaaatccag
    12001 tccatttggg ccgaatatca agattatcaa gacatacgcg tcttagaaat tggtactgac
    12061 ttagcttatt ttaaggcgtt gaaacaaata gcacaaagat tagaggaccc tgttttccaa
    12121 caagctgttc ttattgtgat tgatttgtat aatctgatta ccgtcagacg ggccaaatcg
    12181 caaaataaac caataagttt catgatgcag ttattatctg atgaagcaag tagaccaagt
    12241 aaaacattta tcacacttga agatgataag gatctgatga cgtggtttga aaatgtaaca
    12301 cctgatagct atatgacagc cctaaaacct tattcagaga aacttcgcca aggcactctt
    12361 caaacgactg agttagaata ccttgttgat gaatgccttt accatttatt tgcgaaggcc
    12421 aaatatcaag tcgatgggcc ttatgtgctt gctcgctttt tgctcgctaa atcgtttgaa
    12481 gtaaaaaacc tacggctttt agcggctgct ttagctaatg atttacccaa agaacgtgtc
    12541 atagaaagga tgagaccaat agcatgacca aaacattgta taaagtcggg gtaattggta
    12601 acagagatgt tattctacct tttcagatga ttgggtttca aacttttcca gtaataaaac
    12661 cacaagacgc tattaaccag ttgcgtcaac tagcaatgga agactttggt attatttata
    12721 tcacagaaga tattgctgca gctattccag aagtcctcac tcactatgac aatcaagttc
    12781 taccagcagt cataccatta ccaactcatc aaggagcgca agggataggc ctgtcacgca
    12841 tacaagccat ggttgaaaag gctgtcggtc aaaatatttt ataacactaa gacgttaggc
    12901 aaagaggact tatactctgt ttgaggctta tgagtagcta actgatgaaa tgcaaggaca
    12961 ggaaaattgg tgaagttagc agctgaacgc ataggatagt ttgctgacta ttcaaaatag
    13021 tcacattaaa ccttgacagt atagattagt tagtatgatt tggaaaaaat aaaggaggaa
    13081 aaaggtgaac caaggaaaaa taataaccgt ttcgggacct cttgttgtgg cttctgggat
    13141 gcaagaagct aatattcaag atatttgtcg tgtgggacat cttggcttag tcggagaaat
    13201 tattgaaatg cgtcgcgatc aagcgtctat tcaggtttat gaggaaacat cagggatcgg
    13261 tccaggagaa ccagtagtga ctactggttg tcctttgtcg gtcgagttag gcccgggcct
    13321 gatttcagaa atgtttgacg gtattcagcg accgcttgat cgttttcaaa aagcaacgga
    13381 cagcgacttt ttaatccgtg gtgtggctat cccaagtctt gatcgaaagg ctaagtgggc
    13441 atttattccc aagctaagtg ttggtcaaga agtagttgca ggtgatattt taggaactgt
    13501 gcaagaaaca gctgtcattg agcaccgtat catggttcct tataaagttt cagggacctt
    13561 ggtggctatt catgcagggg acttcacagt aacagataca gtttatgaaa ttaagcagga
    13621 agacggttcc atttaccaag gtagcctcat gcagacttgg ccagttcgtc aaagtcgccc
    13681 tgttgctcaa aagcttatcc cagtcgaacc tttggttaca ggtcaacggg ttattgacac
    13741 ctttttccct gttacaaaag gtggtgccgc tgccgttcct ggaccatttg gggcaggaaa
    13801 aacagttgtg cagcatcaaa tagctaaatt tgccaacgtt gatattgtta tttatgtcgg
    13861 ttgtggggaa cgcggcaacg agatgaccga cgttttgaat gagtttccag agttaattga
    13921 cccaaataca ggccagtcca ttatggagcg cacggtgtta attgcaaaca cctctaatat
    13981 gccagtagca gcgcgtgaag cgtcgattta cacaggtatt accattgccg aatatttccg
    14041 tgatatgggc tattctgtgg ctatcatggc agactcgaca tcacgttggg cagaagctct
    14101 gcgcgagatg tcaggacgcc tacaagaaat gcctggtgat gaaggctacc cggcttactt
    14161 agggagtcgt attgccgaat attatgaacg ggctggtcgt gttcggacct tgggaagtca
    14221 agaacgtgag ggaaccatta cagccatcgg cgcggtttct cctcctggag gggatatttc
    14281 agagcctgtc actcaaaaca cccttcggat tgtcaaagtt ttctgggggc tcgacgcgcc
    14341 tcttgcgcaa cggcgtcact tcccagcgat taactggctg acgtcttatt cattgtatca
    14401 agatgatgta ggaagctata ttgaccgtaa acagcaatct aattggtcca acaaggtaac
    14461 tcgtgccatg gctattttgc agcgtgaagc cagtctagaa gaaattgtac gcttggtggg
    14521 gcttgattca ctgtctgaac aagatcgttt gaccatggct gttgcccggc aaattcggga
    14581 ggattatctc cagcaaaatg cctttgattc ggtggatacc tttacttcct ttccgaaaca
    14641 agaggccatg ctaaccaata ttttgacctt taatgaggaa gccagcaaag ccctttcttt
    14701 gggagcttat tttaatgaga ttatggaagg cactgctcag gtacgcgatc gcatcgcacg
    14761 cagcaaattt atcccagaag aaaacttaga gcagattaaa gggcttactc agaaggttac
    14821 caaagagatt caccacgttt tagcaaaggg aggaatttag atgagcgttc tcaaagaata
    14881 tcggacggtt agcgaagtgg ttggcccttt gatgattgtt gatcaagttg caggagtgca
    14941 ctacaacgaa ttggtagata ttactttgca taatggagaa aggcgtaaag gtcaagtctt
    15001 agaagtccaa ggtgacaagg ctatggtaca gctatttgaa ggatcaactg gcatcaacct
    15061 agccaaaacc aaggttcgat ttacagggca tcctttggaa ttagccgtat cagaagatat
    15121 ggtagggcgc atctttgatg gaatggggca gcccatagac ggcggtccag aacttattcc
    15181 cgaaaaatac cttgatattg atggtcaagc gatcaatcct gtcgctcgtg attacccaga
    15241 cgaatttatc cagacaggta tctcagctat tgatcacctc aataccctcg ttcgtggtca
    15301 aaagttacca gttttttcgg gctcagggtt acctcataat gaattggccg cacagattgc
    15361 tcgtcaggca actgttctaa actctgatga taactttgcg gttgtgtttg cagctatggg
    15421 tattactttt gaagaggcag aattctttat gaatgacttg cgtgaaacgg gtgccattga
    15481 tcgatctgtt ttatttatca atttagctaa tgaccctgct attgaacgca ttgcaacacc
    15541 acgtatagct ctgacaacag ccgaatactt ggcttatgaa aaaggtatgc atgttttagt
    15601 catcatgaca gatatgacaa attattgtga agccttacga gaagtatcag ccgctcgcag
    15661 agaagttcca ggcagacgag gttatcctgg ctatctctat actaatctct ccaccttata
    15721 tgaacgggct ggtcgcttga tcgggaaaaa agggtcagtg actcaaattc ctattttaac
    15781 catgccagaa gatgacatta cccaccctat ccccgatttg acaggttata ttaccgaagg
    15841 tcagattatt ttgtcgcaag aactatataa aaatggtttt agaccgccta ttaatgtctt
    15901 gccatcgcta tctcgcctaa aagataaagg ctcaggtgaa ggtaagactc gacaagacca
    15961 tgctgctaca atgaatcagc tctttgcagc ctatgcccaa ggaaaacaag ctaaggaatt
    16021 ggctgttgtg ctcggtgaat cagccctttc tgaaacggat aaactatatg tggcctttac
    16081 caaccggttt gaagaagaat acattaacca aggattttac accaaccgta gcattgaaga
    16141 aagtcttgac ttgggttggg aattgttgtc gattttgcca cgtaccgaat taaaacgcat
    16201 taaagatgat atgttagatc gttatttgcc taaagcagat accacgatga caaaggtttt
    16261 tgttgcaaat gattgagttg accatgcaat ttcaagccct tgacgaaagg agttatatca
    16321 atggcacgat taaatgttaa accaacacgc atggaactta gtaacttgaa aaatcgcttg
    16381 aagacagcta caagaggtca taaattatta aaggacaagc gggatgagtt gatgcgccgc
    16441 ttcgttgatt taattcgtga aaacaatgag cttcggcaaa ctatcgaaaa agaacttgct
    16501 gccaatatga aggagtttgt cttggcaaaa gcatccgaaa atagtctaat ggtagaagaa
    16561 ctctttgctg ttccagtcca tgaagtgacc ttatggattg atattgaaaa tatcatgagt
    16621 gtcaatgtgc ctaaattcca tgtccagtct aatacggcaa gagagcaaga acaaggtgag
    16681 tttgcttata gttacctcag ctcaaatagt gagatggaca atactatcca aaagacaaaa
    16741 gaactattag aaaagctctt acggttagct gaagttgaaa aaacttgtca actaatggct
    16801 gatgacattg aaaagactag acgtcgcgtc aatggcttag agtattctat tatcccgcaa
    16861 ctgaaagaga cgattcacta cattgagttg aaattagaag aggccgagcg tgcgagcctt
    16921 gttcgtatta tgaaaataac atcataaaag ataagtgtta tatcaaacaa ggcgattatt
    16981 cgttaagtag taaaaaagca agccatcaaa gggattaacc taactgatgg cttgcttttt
    17041 aagtagcgtg acaggtgatg tttagcttat gcgcgagtta ttttatcaat tgttttttga
    17101 gtttccttgc cttcactaag aagtgcttgc acaatatttt ggtcacgtag tttgacagaa
    17161 tcgttaatgg tttcggcaga cctgataata gcactttcta gttgtgctcg ttctttgcgt
    17221 ccatgatcaa tcgccgcaat gatcccatta ttttgtgcta ctaaactttc tgccagactt
    17281 gtcacagatt tcatagacaa agtagggttt tgtgctgatt gttccaatgc tgggatggct
    17341 tctttacttg tttctgctag catctgaagg gcagcattat tagcattaat aatggcatca
    17401 gcagtcattc cagatttaac cgattgttgc atcatgccta actgagcaat agatagtttc
    17461 atcgttggaa tggtattgcg gcgtaacatg cctagttttt gacgcatgtc agaagagacc
    17521 ttgactagat tacgcatttg cggagttgtc gcccaagcaa catagaggcg actcaagtat
    17581 tcggtgtgtt gttgttcgag agtgttgatg acttcggtag ttcttgccaa aagatcagct
    17641 tttatttgat agtctggtgt agcactgtct ttggttttta ggtctttttg taaagccgca
    17701 gcgcgctgac tagcttcttt ttgactagct tcgataaaag caatgacgcc taccaaatgt
    17761 tcaatggact tagtattatc ttcaattaac aattctgctg agacaatatt gcgagctaag
    17821 gtatcttctt gcttgacaac cgctgcagcc atactatcca ttttttgctc aatgttttga
    17881 gaatcaaaat aaaactcttg cagggtatca cggctttgtt taaagagttt ttgaagaaag
    17941 tttggctttt tatcaaggtc cacaggtgtg gcatccttgt atttagcgat aaaaccattg
    18001 agttcacgat tggttgattt taaaagatca tccacttgtg gaatctgtaa ttttttttgc
    18061 tctgccaaga tatgattaac cgttgcattg accccttcaa cagcagactg accaaaatca
    18121 agtagcgcat tttggtctgc caaaaaggta tctaccaatg ccggggcttt ggcagtaata
    18181 gctgtctgct ggtcagcact tagtttctca aaaaaagaga tttggccatt tgtgtcagtt
    18241 ggtaagtctg agataatatc ggtggtttta tcggttttga taacagcatt gtcagcaatt
    18301 tggtcaatgt caaaattaaa atctgccata aagggactcc tttagtcttt ttggtgatgc
    18361 gttgttcgtc tttgagtagc accttgcatg attcgaaggc taatatcaaa atctttaaga
    18421 tcactttcat tgagtcgacg aagggtttcg tcaagatctt catcaaattg ttggatagct
    18481 tgtttggctt gttctaaacg agcagcagcg ttatagtaat ttttaggctc ttctttgatt
    18541 tttaagtagc ctgttaagat atcctcaaac ctcctcatgt tagcatcatg cagcgcaagc
    18601 aattcttctt gattgtcggc tccttggatt ttagcaagga tagcttgatg atctgtctga
    18661 atattatcat aatacggttt gagctcaggt gctttgttaa taagattagg agatggggtt
    18721 ttcaaaggct gagggttaag agttgtggca atctgcagtg tttcgagttg aagggtaata
    18781 tcactttcaa cgtcattggc ttttttggtg atacgacgat aaatttgggg atctaactgg
    18841 tcttttaacg taatagcttt tgctttgatg tcactaagtt gtggtaataa ttgctgagct
    18901 agtacgttat attggaagtc atcatggtct gccagataag tgtctaacag ccgaacttta
    18961 cgatcagcta gctgaatttt tgcttttaga tcttctaatt gtttggcaat cttggccttt
    19021 gctagccgct tttgatgaga tctaacacga aaaatagcat aacctgtacc accaatggct
    19081 atggcaggca aaatgtctag aagtgactca gtaaaagaag agccacctat aaagcttgaa
    19141 atcataaaaa aagcaatgat tagccaaatc cagtttagtg atttcttttt tgtgctcgtg
    19201 cggtcatact ttctaatcat gtgatatttc ctcgatatgt ttttactggc tatctcatag
    19261 aggtaactta ctattatttt accttaaaac cgctatttct gaaagaaaag agctaatgtt
    19321 ttaagagaat cgtttaaccc tgctaaagct taggagaaac gaggttaaaa gcttttctct
    19381 tataatgttc gtttttttag gattgtttat catggttaaa aaaagagttt ctctttttcc
    19441 ttaataatgc taagaaatct agcagaaaaa atcatttttt gctataataa gttgtaagat
    19501 atatgctagc aggtgagatt cctgcctgtt ttctttaaat atcaagagct acattgctga
    19561 tcttacagat ctgaccttct ttttggtttt taagcagtgg ttagcttgcc tatgattttt
    19621 attgagaata agtgtttcag aaagttagga caatgatatg acatctgtag ttgttgttgg
    19681 tacccagtgg ggtgacgaag gtaaaggtaa aatcactgat ttcttgtcag cggatgcaga
    19741 agtaattgct cgctatcaag gtggtgataa tgctggtcat acgatcgtga ttgatggtaa
    19801 gaagtttaaa cttcacttga tcccatcagg aattttcttc ccgcaaaaaa tttccgttat
    19861 tggtaatggc gttgtggtca accccaaatc tttggtcaaa gagttggcgt acctgcatga
    19921 tgaaggagtg acgacagata accttcgcat ttcagaccga gctcatgtta ttttacctta
    19981 tcatatccag ctggatcaac tgcaagaaga tgcaaaaggt gacaataaaa tcggaacaac
    20041 tattaaaggg attggtccag cttatatgga taaagctgct cgagttggta tccgtatcgc
    20101 agatttactg gataaggata tctttgcaga gcgcctacgc attaatttag ctgagaaaaa
    20161 ccgtttattt gaaaaaatgt atgacagtac acctcttggt tttgatgcta tctttgagga
    20221 gtactatgct tacggtcaag aaatcaagca atatgtgaca gatacttctg tgattttaaa
    20281 tgatgcactt gatgctggta aacgtgttct ttttgaaggt gctcaagggg ttatgcttga
    20341 tattgaccaa ggaacttacc catttgtaac gtcttcaaac ccagttgctg gtggtgtaac
    20401 cattggttct ggtgttggcc caagtaaaat caacaaagta gttggtgtct gtaaagccta
    20461 cacaagccgt gtcggtgatg ggccattccc tacagaactc tttgatgaag tgggtgagcg
    20521 cattcgtgaa gtgggtcatg agtacgggac aacgaccggc cgtccacgtc gtgtcggttg
    20581 gtttgactca gttgttatgc gccatagtcg tcgtgtgtca gggattacta acctctctct
    20641 gaattcaatt gatgttcttt cagggcttga tacggttaag atttgtgtgg cttatgacct
    20701 tgatgggaaa cgtattgact attacccagc aagccttgaa caactcaaac gttgcaaacc
    20761 aatctatgaa gaattaccag gctggcaaga ggacatcaca ggtgttcgta gccttgatga
    20821 gcttcctgaa aatgcccgca actacgttcg tcgtgttgga gaattggttg gcgttcgcat
    20881 ttcaaccttc tcagttggtc cagggcgtga acagaccaat attcttgagt cagtctgggc
    20941 atctatctaa ggtgtctagt atgacaaaga gttggatagc gtttccagct ctttttaccg
    21001 cttgttggat tgtatagtta gtcatgctat tactagtagc ttgagttttg tcgttgtctt
    21061 atctccttaa gaggtgattt ttgaggagat aacgggtttt accagttgat ctcactttct
    21121 cgttcggtca ttttggtgaa aaagagattt ttcagcaaaa atagtaggat aaaactgatt
    21181 tttttgatat actaaacttt tcgttctaga gcataagtag aacgttaaca atgacacatc
    21241 actttaggat taaacattta ggaggttcat tttcacatga acaaaaaagt aatgtcactt
    21301 ggtcttgttt cgactgccct attcacatta ggaggctgca ccaataactc ctctaaacaa
    21361 acaactgaca attcattaaa aatcgctatg atcactaatc agacgggtat tgatgacaag
    21421 tcatttaacc agtcagcctg ggaaggctta caagcttggg gaaaagaaaa taaacttgaa
    21481 aaaggaaaag gctatgatta tttccaatca gccaatgaat cagagtttac cacaaacctt
    21541 gagtcagcag taaccaatgg ttataatctt gtttttggga ttggatttcc attacatgac
    21601 gctgtagaaa aagtagccgc aaacaatcct gacaaccatt ttgcaattgt ggatgatgtg
    21661 attaaaggtc aaaaaaatgt tgcaagtatc accttttcag accatgaagc ggcataccta
    21721 gccggtgttg cagcagctaa aacgacaaaa accaagcaag ttggttttgt aggtggtatg
    21781 gaaggagatg ttgtcaagcg ctttgaaaaa ggttttgaag ctggtgtgaa atcagtagat
    21841 gataccatca aagtaagagt tgcttatgca ggctcttttg cagatgctgc caaaggcaag
    21901 acgattgcag ctgctcaata tgctgaaggc gcagatgtta tttatcatgc agcaggaggc
    21961 acaggggcgg gtgtctttag cgaagctaag tctatcaacg aaaaacgtaa agaagaagat
    22021 aaggtttggg ttattggtgt tgaccgtgac caaagtgaag atggaaaata caccacaaaa
    22081 gatggcaagt cagctaattt tgttttgacc tcaagtatca aggaagtcgg aaaagcttta
    22141 gtaaaagtag ccgtaaaaac ctcagaaggc caattcccag gtggtcaaat aaccactttt
    22201 ggtttaaaag aaggtggtgt tagccttaca acggatgctc tgacacaaga cactaaaaaa
    22261 gctattgaga ctgctaaaaa agcgattatc gaaggaacca tcacagttcc tgaaaactaa
    22321 aactgtacaa taccgtccag agtcgtcacg aaccgacttt ggacttttta ataaaggtgt
    22381 caagtagctc cacagatacg ttgacaccag ccctgtcttt tattataatg aaggtgatag
    22441 aaaacagcgc aaaagccaaa aaaagggctt ttttataatg aaaggaaaca tcatgctaga
    22501 ttcatttgat aagggctggt tcgtcctcca aacttactca ggctacgaaa acaaagtaaa
    22561 agaaaacctc ttgcaacgtg cccaaaccta taacatgttg gacaatattt tgcgcgtcga
    22621 aattccgaca caaacggtta acgttgaaaa aaatgggcaa accaaagaaa tcgaagaaaa
    22681 tcgctttcca gggtatgtct tggttgaaat ggtcatgaca gatgaagctt ggtttgttgt
    22741 gcgtaacaca ccaaacgtta caggttttgt gggatcacac gggaaccgat caaaaccaac
    22801 accacttctt gaagaagaaa tccgtgctat cttgttgtct atgggtcaaa ccattgatgt
    22861 ctttgatacc aatatcaaag aaggtgatgt ggttcagatc atagacggtg cctttatggg
    22921 acaagaaggt cgtgtggtag aaatcgaaaa caacaaagtg aagctgatgc tcaacatgtt
    22981 tggctctgaa acagtagcag aagttgaact ttatcaaatt gcagaactat aggctctcaa
    23041 aggtctgatg gtataagtat taccatcaga ccttttttag ttggcagtga agcgtgttta
    23101 caaaccaatg gatgactatt gttaacatca ttgtaatcag aaataattaa cagatctatt
    23161 actgataacg gtgctactat caaatattta actagtactt ttaatctggt ttaaatagaa
    23221 cagatgtgaa ggttctgtga taataagatg gaaatatccc cttgaaactt gtaacagttg
    23281 gctacttgtt tttttgtgtt catttttttg atagaaaagc ctaaaacgat gttaataaat
    23341 cgcattgaca aaaactagtt gttaatgtat agtttactta aaaataatat aaggtggttt
    23401 acatgagaaa caaaaaagta acattagctc atattgtcgc aaagacaagt gttgctattg
    23461 ctttggctgg agcaatgggt agcagtttat tagctaatag cacaacgtac gctgttagtg
    23521 gcaaagaaaa taaaaaaagc gatgtcaaat atgaaacgac caaagttatg gaagctaacg
    23581 caacttcctc taaagaagac aatcatgtca tgcacacatt agacggctca atgagtactg
    23641 tctgggagga aaattcacct ggtggtggcg ttggtgaggt actttcctac aagtttgttt
    23701 ccccgatgcg tattgggaga attttaattg tgaatggaga tacatctagc aaggagaatt
    23761 actacaagaa aaatagaatt gcaaaggctg atgttaaata ctataacggg aataaattgg
    23821 tcctctttca aaaaattgaa ttaggcgaca cctacactaa aaaaccgcat cacattgaga
    23881 ttgataaaaa attagatgtt gatcgtattg atattgaggt aacagaggtc catcagggac
    23941 aaaacaagga tattttagcc ttgtcagagg tcacttttgg caatatggaa cgcgatcttt
    24001 ttgaaaaaaa gtttaaagaa attaaagata aatgggtaac agataaacaa gcagatgagt
    24061 ttattgaaac tgccgacaag tatgctgata aagctgttca gatgtctgct gttgcgtcac
    24121 gtgctgagta ttaccggatg tacgttagcc gcaaatacca ctacaaaaaa gagtttgttg
    24181 aaaaactaaa acaagtctac aaagaaagcg gagcttctca cgttacaagt aaaaaagatt
    24241 tgatgttagc ttttgatgat gctaaaagaa agtcaacgat tggtcgacaa gaaaacggtc
    24301 tttttgtgac aagttttgct gaagatatgg cattgctctt tactgatcaa ggtaagttaa
    24361 aatcagctga ccaaattgaa aatataaaag gtgtcgatag cggaaaatat agcgatggag
    24421 tttatcaata tgagtacgat tctgaactaa caaaaaacat tgataagcta ggctatatcc
    24481 gaacagctag cggagatacc cctggagcaa attcgctcaa cattcctggt tgccaaacgt
    24541 ggtcaggaaa acacattgaa aattcagaaa gtgagttaat tttcccatcg attagtgtta
    24601 aagatctaaa atctaaagct gtcttagcag agattgatgc caaaggctat tttgaaatta
    24661 ttgatcctac catcattgct ccaaatggtg accataaaaa agtaactggt cgcttcaaaa
    24721 ttaagaaaat gcaagataga atgcaagata ggaagtaaca atatgtataa ggtgccaaag
    24781 agtttagaac attaccaaaa aatgtttcaa aaagaagtaa ctgttaatga tttaaaaaaa
    24841 tacttgatag gtagtgacaa agagtatcgt atcactagaa gagactccta tatgggagat
    24901 atttctgatc cagaagttat tttagagtat ggggtttacc ctgctttcat aaaaggctat
    24961 acccaattga aagctaacat cgaagaagca ttattagaaa tgtcaaatag cggtcaagca
    25021 ttagacattt accaagcggt tcaaacccta aacgctgaaa acatgttatt aaattattac
    25081 gaaagcttgc cattttattt aaaccgtcaa agcatactag ctaatataac caaagcgtta
    25141 aaagatgcgc atattagaga ggctatggta cattacaaat taggagaatt tgctcactat
    25201 caagatacta tgcttgatat ggtcgaaaga acaatagaaa cattttagaa tgataaaaag
    25261 gtatgaagga catgtctaac aaaaaaacat ttaaaaaata cagtcgcgtc gctgggctac
    25321 taacggcagc tcttatcatt ggtaatcttg ttactgctaa tgctgaatcg aacaaacaaa
    25381 acactgctag tacagaaacc acaacgacaa atgagcaacc aaagccagaa agtagtgagc
    25441 taactaccga aaaagcaggt cagaaaatgg atgatatgct taactctaac gatatgatta
    25501 agcttgctcc caaagaaatg ccactagaat ctgcagaaaa agaagaaaaa aagtcagaag
    25561 acaaaaaaaa gagcgaagaa gatcacactg aagaaatcaa tgacaagatt tattcactaa
    25621 attataatga gcttgaagta cttgctaaaa atggtgaaac cattgaaaat tttgttccta
    25681 aagaaggcgt taagaaagct gataaattta ttgtcattga aagaaagaaa aaaaatatca
    25741 acactacacc agtcgatatt tccatcattg actctgtcac tgataggacc tatccagcag
    25801 cccttcagct ggctaataaa ggttttaccg aaaacaaacc agacgcggta gtcaccaagc
    25861 gaaacccaca aaaaatccat attgatttac caggtatggg agacaaagca acggttgagg
    25921 tcaatgaccc tacctatgcc aatgtttcaa cagctattga taatcttgtt aaccaatggc
    25981 atgataatta ttctggtggt aatacgcttc ctgccagaac acaatatact gaatcaatgg
    26041 tatattctaa atcacagatt gaagcagctc taaatgttaa tagtaaaatc ttagatggta
    26101 ctttaggcat tgatttcaag tcgatttcaa aaggtgaaaa gaaggtgatg attgcagcat
    26161 acaagcaaat tttttacacc gtatcagcaa accttcctaa taatcctgcg gatgtgtttg
    26221 ataaatcagt gacctttaaa gagttgcaac gaaaaggtgt cagcaatgaa gccccgccac
    26281 tctttgtgag taacgtagct tatggtcgaa ctgtttttgt caaactagaa acaagttcta
    26341 aaagtaatga tgttgaagcg gcctttagtg cagctctaaa aggaacagat gttaaaacta
    26401 atggaaaata ctctgatatt ttagaaaata gttcatttac agctgtcgtt ttaggaggag
    26461 atgctgcaga gcacaataag gtagtcacaa aagactttga tgttattaga aacgttatca
    26521 aagataatgc taccttcagt agaaaaaacc cagcttatcc tatttcatac accagtgttt
    26581 tccttaaaaa taataaaatt gcgggtgtca ataacagaag tgaatacgtt gaaacaacat
    26641 ctaccgagta cacgagtgga aaaattaacc tgtctcatca aggtgcctat gttgctcaat
    26701 atgaaatcct ttgggatgaa atcaattatg atgacaaagg aaaagaagtg attacaaaac
    26761 gacgttggga caacaactgg tatagtaaga catcaccatt tagcacagtt atcccactag
    26821 gagctaattc acgaaatatc cgtatcatgg ctagagagtg caccggctta gcttgggaat
    26881 ggtggcgaaa agtgatcgac gaaagagatg tgaaactgtc taaagaaatc aatgtcaaca
    26941 tctcaggatc aaccttgagc ccatatggtt cgattactta taagtaggac tggttcaaga
    27001 ggttcgtcaa gcaccttgat gctgcttatc tcttgaggcc ttgtgcctaa tcctctcaca
    27061 aatacagaag aaagcttgtc tatgagatac cttcatagac aagctttttt gatatactaa
    27121 tcaaaaaatt attcttttct cacatcgtga ccttgaagct aagctgcttc taatctataa
    27181 tactaacaag ctgcttttta acaagcaaag cataacataa aagggagaga taactattat
    27241 catgaaacaa caatcttacc agcctctacg cttcgtctac ctcttggtgg ctctatttgc
    27301 tgctatgttg cttatagcaa gacctgttat ggcagatggg gagaataatg acccagctaa
    27361 tgcagcatat tataaaggga aaagcgctgg agaagaagca gggaaaacag ctggaaaaga
    27421 agctagttgg actgatttga ccccaactaa tccaaccatt ccagaaccac ctagtgatat
    27481 cagagagact actaataaac agcattataa agacgggtat acagatgggt acagagatgg
    27541 ttataatgaa ggctggaaat ctcagcatcc cgtcttgact ccggtcaagg ttatatggga
    27601 tttgatctct cattggctac agcaattctt ccccaataac caggcaacta caacagtaca
    27661 aagcatgtca taataaaaat gaattaaaaa cagcctttaa ctgctaatgt gaaaggttgt
    27721 ttttttagga tatgggaatg aacaataaaa aaagagtttg tgaaaaagcc tctcggccac
    27781 acaaaaaaac aatggcgtca aagccattgt ttttttagca taatcaagag actactgtct
    27841 cagactctca agtaattttt actcagagta gtaatatccc caagtgcaat aatatgctgc
    27901 tgacttgccc caacctctta acaaatcgcg catacaggtc aatggacaac aagaccattt
    27961 tggaccacaa tctggacatc ctacacaagt aacttgcgtg tcatttgctg aaacagtttg
    28021 gttttctggt gttgcaaggc taaggcttac gacagcagca gttgcgatca taaataaaga
    28081 taatttcttt ttcatttgta actccttaaa ttatagtata cctatattat actcatatta
    28141 tgttaatgat tcaatatcac attttaatct ttttgttatg tgtttgaccg aaaaaggcaa
    28201 agaaagccga tactaaagca tttctttatc ttatataaat aacattaatt attaataatg
    28261 ttaatctggt tataattata tttgaggtgt tacagctttt ttggtggtgg ttagctagca
    28321 actgttacga cttgtgtttt gggcttgtcc ttttataggc ggtatgcctt ttctttttaa
    28381 tcttgaggga tcgttagtaa aaacgtttta gccaatcaaa aagcctagaa ctgcttacgc
    28441 agctctaggc ttttcataac cgtagtctta cgaagaagat agcttctatg ttacggtatt
    28501 aggtttacca tactgtgtaa agtaaccagc tgtcaggacc agtgtgtccg tagaaaccgt
    28561 tactatagct agcatcattt gctgaaacag tttggtggct tcctagtgtt gcaaggctaa
    28621 ggcctgcaac agcagcagtt gcgatcataa ataaagata
//
LOCUS       DAUGJR010000022        28318 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUGJR010000022 DAUGJR010000000
VERSION     DAUGJR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28318
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.022"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(103..861)
                     /locus_tag="VH800_000996"
     CDS             complement(103..861)
                     /locus_tag="VH800_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362073.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDSKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(858..1727)
                     /locus_tag="VH800_000997"
     CDS             complement(858..1727)
                     /locus_tag="VH800_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362074.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERFFKGVRLTR"
     gene            complement(2073..3071)
                     /locus_tag="VH800_000998"
     CDS             complement(2073..3071)
                     /locus_tag="VH800_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8362075.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAATSKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAIKKEDFPSASFIEN"
     gene            3425..5077
                     /gene="fbp54"
                     /locus_tag="VH800_000999"
     CDS             3425..5077
                     /gene="fbp54"
                     /locus_tag="VH800_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEQ8362076.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGTTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(5136..6383)
                     /locus_tag="VH800_001000"
     CDS             complement(5136..6383)
                     /locus_tag="VH800_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEQ8362077.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVGISPEPLVIFGLAEIDMSLQHFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLMYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(6373..7554)
                     /locus_tag="VH800_001001"
     CDS             complement(6373..7554)
                     /locus_tag="VH800_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8362078.1"
                     /translation="MPLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(7612..8088)
                     /locus_tag="VH800_001002"
     CDS             complement(7612..8088)
                     /locus_tag="VH800_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEQ8362079.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(8309..9349)
                     /gene="rfbB"
                     /locus_tag="VH800_001003"
     CDS             complement(8309..9349)
                     /gene="rfbB"
                     /locus_tag="VH800_001003"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEQ8362080.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDVIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(9593..10186)
                     /locus_tag="VH800_001004"
     CDS             complement(9593..10186)
                     /locus_tag="VH800_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEQ8362081.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(10186..11055)
                     /gene="rfbA"
                     /locus_tag="VH800_001005"
     CDS             complement(10186..11055)
                     /gene="rfbA"
                     /locus_tag="VH800_001005"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEQ8362082.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDVLIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(11113..12219)
                     /locus_tag="VH800_001006"
     CDS             complement(11113..12219)
                     /locus_tag="VH800_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEQ8362083.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAVKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDTYPVVMPEGEIDLIPFNQGKISVGTSHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVSGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(12259..13047)
                     /locus_tag="VH800_001007"
     CDS             complement(12259..13047)
                     /locus_tag="VH800_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEQ8362084.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(13037..13723)
                     /locus_tag="VH800_001008"
     CDS             complement(13037..13723)
                     /locus_tag="VH800_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEQ8362085.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(13795..14451)
                     /gene="nth"
                     /locus_tag="VH800_001009"
     CDS             complement(13795..14451)
                     /gene="nth"
                     /locus_tag="VH800_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEQ8362086.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQDTYGKSKA
                     "
     gene            complement(14448..15131)
                     /locus_tag="VH800_001010"
     CDS             complement(14448..15131)
                     /locus_tag="VH800_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ8362087.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTNQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(15212..15730)
                     /locus_tag="VH800_001011"
     CDS             complement(15212..15730)
                     /locus_tag="VH800_001011"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEQ8362088.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(15881..18091)
                     /gene="recJ"
                     /locus_tag="VH800_001012"
     CDS             complement(15881..18091)
                     /gene="recJ"
                     /locus_tag="VH800_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEQ8362089.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(18088..18852)
                     /locus_tag="VH800_001013"
     CDS             complement(18088..18852)
                     /locus_tag="VH800_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ8362090.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(18852..19781)
                     /locus_tag="VH800_001014"
     CDS             complement(18852..19781)
                     /locus_tag="VH800_001014"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEQ8362091.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(19796..20431)
                     /locus_tag="VH800_001015"
     CDS             complement(19796..20431)
                     /locus_tag="VH800_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEQ8362092.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(20424..21662)
                     /gene="hflX"
                     /locus_tag="VH800_001016"
     CDS             complement(20424..21662)
                     /gene="hflX"
                     /locus_tag="VH800_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEQ8362093.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(21735..22634)
                     /gene="miaA"
                     /locus_tag="VH800_001017"
     CDS             complement(21735..22634)
                     /gene="miaA"
                     /locus_tag="VH800_001017"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEQ8362094.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKSISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMIENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            22768..22944
                     /locus_tag="VH800_001018"
     CDS             22768..22944
                     /locus_tag="VH800_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEQ8362095.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(23062..23970)
                     /locus_tag="VH800_001019"
     CDS             complement(23062..23970)
                     /locus_tag="VH800_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEQ8362096.1"
                     /translation="MKHLKTPPLVMSGLALGTLSFGNLLATYVSIFNYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     VSSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(24207..24626)
                     /locus_tag="VH800_001020"
     CDS             complement(24207..24626)
                     /locus_tag="VH800_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEQ8362097.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMI
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDSLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMVEDSAVQQVLNAAH"
     gene            complement(24937..25923)
                     /locus_tag="VH800_001021"
     CDS             complement(24937..25923)
                     /locus_tag="VH800_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEQ8362098.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            26122..26424
                     /locus_tag="VH800_001022"
     CDS             26122..26424
                     /locus_tag="VH800_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362099.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(26787..26858)
                     /locus_tag="VH800_001023"
     tRNA            complement(26787..26858)
                     /locus_tag="VH800_001023"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(26823..26825),aa:Arg,seq:ccg)
     gene            complement(26971..28176)
                     /gene="rpsA"
                     /locus_tag="VH800_001024"
     CDS             complement(26971..28176)
                     /gene="rpsA"
                     /locus_tag="VH800_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEQ8362100.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
BASE COUNT         8630 a         6079 c         4975 g         8634 t
ORIGIN      
        1 gaggcgtttt ttctctaaat agccttgata ctttcagatt attttcagta tggaaatcaa
       61 aaaatcactg acttattatt agtcaatgat ttagatcgtt gattaatcaa atagttggta
      121 atagtcagta atcgtcagtt gttctttttc catttgattt aaatctttaa taatgtttcc
      181 atctttcatt acaatcagac gattcccata agttaatgca tcttccatat ggtgggtaat
      241 catcaaagct gttaagccat cttttgtcac aaactcatct gtcaattgca ttaaagattg
      301 actcgtctta gggtcaagag cagccgtatg ttcatctaat aataagagag ctggcttttt
      361 caacgttgcc attaataaac ttaaagcttg tctttgtcca ccagacaaaa gacctgctgg
      421 tgtttctaaa tgcttttcta ggccatttcc tgttcgttta accaaatcct caaaactagc
      481 taagtgctct gttatttttc gagaagccaa ggagcgtttt tctcctcttt gacgtgcgat
      541 taagagattt tcagccactg tcatccgagg ggctgttccc attttggaat cttgaaagac
      601 tcgcgatagg taaagagctc ttttttctgc tggccaatgc gtcacatcct gaccaagaat
      661 cctaatttgc ccccgtgtca aacttagcgt tcctgcaatt acattaaaaa gggttgattt
      721 tccagctcca tttcctccta aaatagttaa aaaatcatgt tcatagatag ttagtgtcac
      781 attgtccaat attgttttag catcttcaaa accattatct acgtcaactg ttgcattgat
      841 caattcaata atttttgtca tcgtgttaac ctcactccct taaagaagcg ctcttttacc
      901 actggtatca tgaggcacag tgctaaaaca agagcactaa ttaatttcaa ataacttgta
      961 ttaaaaccta gcgtaataac tactgaaatt aaaaattgat aaagaatcga gcctattaca
     1021 atagcaatca aacgttctaa aagagtcagt ccagttgagt atagtacttc accaacaatt
     1081 atgctcgcca aaccaataac aataactcca atcccttttg agacatctgc atagccatct
     1141 tgttggctca ctagagcacc tgataaagct attaaactat tagaaaccac aagtcccata
     1201 acttccatcc aatccgtgtt aataccaaaa ctcttagcca tatctttatt gtctcccgta
     1261 gcgatataag cttgacctag attagtgtaa aggaaataga tcaaaacgct aataacaatc
     1321 acaacagtta tcagacctgt taaaaggcta tttaaatcaa ttgaaaaagg taaacaatcc
     1381 tgaatacgtt tatgatcatg taaacccaag tttgctcttc ccattaccat tagcataatg
     1441 gagttacatg acgtcatcac caaaattccc gctaaaagtg ttggcatttt tcctttcgta
     1501 tataacagcc ctgttaaaaa acctgctaaa gcacctgata acataccaag taaggttgat
     1561 agaaatggat tccaccctaa gctaatagcg gtgaccgcaa cagctcctcc taaaggaaaa
     1621 gaaccttctg tagtcatgtc agggaagttt aaaatcctaa aggtcaggta gattcctaat
     1681 cctaaaactc cccatataag gccttgtgaa actgatgaaa taatcatatt tttcctcata
     1741 tttatattag cgggtaactc tcgccagtat aaaccctttc tttacattaa tttttagatt
     1801 tgttttatac ttagttcagc accgtggctt agtctttttt ttcaatcact ttgacgaaac
     1861 taagacagaa aacaaaaaag tcgagaatca tgtttaaact tactcaaaag gcaagatttt
     1921 ttacgtgtct aaaatagagc attttaaaac taaaaatgat aaaaataacc gttacatcct
     1981 caaaacgatt gtctaacttg gcatccaaat tcatctcagt gagggtgttt tttatggttt
     2041 tttcttgacc ttttatatca catgtcattg tattaattct caataaaaga agctgaagga
     2101 aaatcttctt ttttaatagc aatacctaat tctgctgcta cattcttatt aattagcggt
     2161 tgaccaatat ccacaacttt gacaggaaca tctacaacac gctttccttt gattaatttt
     2221 aacacctgat tagctgtttg aactcccaaa tcgtactgat tttgagaaat agctgccaaa
     2281 ccaccttttt caaccattcg atcaacgcta gtgtagacag gaatctttgc agccttgctg
     2341 gttgtcatga ctgatgaaaa tgcacttgct atagtattgt cttgggggat aaataccgcg
     2401 tctactttac ctaacataac tgacatcgtg gcaggaactt cattagtaga aggaaccgcg
     2461 tatgaaataa cttggtagcc ctttttgcga gctaaccgcc taaactcttt aacttgagat
     2521 aaggaattat cctcattact tgcatataaa attccaactg ttttgacatg tggtgtcagc
     2581 tttttcatta aatcaattgt ctgtttaaca ggcactttat tagatagacc agttacatta
     2641 gcttcaggtt gatccaattg catcactaat ctagatccta ctggatcaga tactgctgac
     2701 atgacaactg ggatatcctt gctggtggct gctaagcctt gcgccgccgg ggttgcgata
     2761 ccaatcacga tatcacttcc tgattgcact aattgcctac tcattgtttg gattttactc
     2821 tgatccccct cagcattcat aaccttaatc actacatttt gtttttgagg catctgcttt
     2881 ttgagttgat cttcaatacc tcgcttaata tcatcaagag cctcatgagt aacgaattgt
     2941 aagatgccaa ttgtaatgtt ttgttggtta gccaaatcac ggttttcctt tgatactcct
     3001 tttgataata gagagcctat cactattaca gttaaaacaa ggagggtagc tattaaactc
     3061 ttgtttttca tctgaattcc tcacatttca tgtcaatctc tttaaaacgt tgatgatgag
     3121 aatacttctc aaaagaaaaa gcacttagta atgattacta ggcgctcttg tgaaatccaa
     3181 tgtcagcgca tagatatctt tttagaagta ctctaaaagt cgtatctatg ccaattcata
     3241 aacacaactt atctatgcca gctttgccaa tttgctaagt gttgtgtttt taccatcatt
     3301 gacttccttt ctcgtttttt taacattata acctaaatca aaaaaattgc aagctctttc
     3361 gtccatattt ttagtcaagt atttgtggta taatgaagag attagaattc agaaaggaga
     3421 aaccatgtct tttgacggct ttttcttaca ccatttaacc aacgaattaa aagagaactt
     3481 gctttacggt cgtatccaaa aggtcaatca accctttgaa cgggaacttg tcttaaccat
     3541 tcgtaaccat cgcaagaatt ataaattgct attgtctgcc catcctgttt ttggaagggt
     3601 acaaatcacc caagcagact ttcaaaatcc tcaggtacct aataccttta ccatgattat
     3661 gcgtaaatac ctccagggtg cagtcattga gcagttagaa cagattgata atgaccgcat
     3721 tatcgaaatc aaggtatcta ataaaaatga aatcggagat gctattcagg caaccctaat
     3781 cattgaaatc atggggaagc acagtaatat catcttggtg gaccgtgcag aaaataaaat
     3841 catcgaatcc attaaacatg ttggtttttc acaaaactct taccgcacca ttttacctgg
     3901 ctctacctac attgagcctc ctaaaacagc tgctgttaat ccttttacaa ttacagatgt
     3961 gcctctattt gaaatcctcc aaacacaaga actaacagtt aaaagcttgc aacagcattt
     4021 tcaaggtttg gggcgagaca ccgcaaaaga gttggccgag cttctgacca cagacaaatt
     4081 aaaacggttc cgtgagtttt ttgctagacc tactcaggca aatctgacca cagcttcttt
     4141 tgcgcctgtt cttttctcag atagtcatgc gacgtttgag actttgtctg acatgcttga
     4201 ccacttttat caagacaagg ctgagcgtga ccgtatcaat cagcaagcca gtgatttgat
     4261 ccaccgtgtg caaactgaac tggacaaaaa tcgcaacaag ctaagtaagc aagaagctga
     4321 gctgctagcc actgaaaatg ctgagttgtt ccgtcaaaaa ggagaattat tgaccaccta
     4381 cctcagtctg gtcccaaaca accaagactc tgtgatttta gacaattatt atacagggga
     4441 aaaaattgag attgccttag acaaggctct gacaccaaat caaaatgctc aacgttattt
     4501 taaaaaatac caaaagctaa aagaagctgt caaacactta tctggattga ttgccgatac
     4561 caagcaaagt attacttact ttgagagcgt agactacaat ttatctcaag caagtatcga
     4621 cgacatcgaa gatattcgcg aagaattata tcaggctggc tttttgaaaa gtcgccaaag
     4681 agacaaacgc cataaacgta aaaagcctga gcagtacctg gcttcagatg gaacaaccat
     4741 tctcatggtg ggacgcaata acttgcaaaa tgaagaactc acctttaaaa tggctaaaaa
     4801 aggagaactc tggttccatg ctaaggatat ccctggaagt catgtcatca tcaaagacaa
     4861 tcttgaccca agtgacgagg ttaaaactga tgctgccgaa ctagctgctt attattcgaa
     4921 agctaggtta tcaaatctcg ttcaggtcga tatgattgaa gctaaaaaat tacacaaacc
     4981 tagtggcgcc aagccaggat ttgtgactta tactggtcaa aaaactttac gggttactcc
     5041 tgaccaagcc aaaattctct ctatgaaatt atcctgataa gcaactaaaa aacagctctc
     5101 ctaggaaagt tatttcccct aggagaactg tttttttatt ctgattgttg gtgcttgata
     5161 tggtcaagaa agtcttgcat attcacatca tcaggcactt gtctgaggta agcggtagcc
     5221 atttggatag ccttgtgaaa ctggccaaac tcccttaata aataggcata atcctgtaaa
     5281 aactctggat tttctgccaa atcagccgaa atctcattat aaagagccaa ggcaacttct
     5341 tcttgttcca aggcgtggta agcctttgca atggtccatt tggttaagac attatcaatc
     5401 gtctcacgat taagagcaat aacctcctca aaacgctcgg catcaaaata aagggtcact
     5461 aaacgcatga gaatctcttc gtcatcaaca gctacttcct ttgcttgaag caggtaattt
     5521 tcagcattct gcctatcgtg taattcataa gaaagctgcg atgctagtaa taataattga
     5581 ctgtcaaatg catttttacg taggccctgt tgaaccaagc gcaaagcttc tgacgtctta
     5641 tgctcttcat gaagactcaa agcataacca tattcataac ctggataatc tggattgatg
     5701 gtttccaact gtttaaagta aagattggct ttttgataat tttcttggtc atacatgagg
     5761 gtcgccaatt caaaaacagt ttcatcttcg tattcaatgg ccacggcctt ttccaagaat
     5821 tcgatggctg cctcaaattt ccctaagcta gcataggctc gtccaatgcg ttgataagtg
     5881 gaaatacctg tcaattcaag gatttgacga ttgtctaact gtgcatagta atcaatagct
     5941 tctttaaaat gctgcaagga catgtcaatt tctgccaaac caaaaatgac caatggctct
     6001 gggctgatgc ccactgcttg aagcaatttt tcacgcgcca cctctgtcag tccttccatg
     6061 tcatagaggt cagccattac taagagagct gacaaataat tggggctatc ttttgaaacc
     6121 ttatccaaat acaagaaagc ttcttcaatg gcgtcgtctt ctgctgcaat ctgagctaaa
     6181 tttatattga gttctgggta atcatcagct aactgcaaat aaatacgctt ggcatgtggc
     6241 aaaaaaccta tactttctaa gtattctcct aaggcgatta aactatctgc atcatcttct
     6301 tttaaagctt tttggaaata tttttcagcg tgcgctaggt cttgctgatc caaggaagca
     6361 atcatttttt cactatttaa catggtcctt aacctcctca atcaccaata cttcttcgtc
     6421 atacaaaccg ctaacttttt tgtaccagtc aaataattct ttaatcacaa ctttgacaga
     6481 agcgtagatt gggatgacaa ggaaaacacc ccagacacca aacatagagc ctgcagtcaa
     6541 taacaagaac ataatggtaa taggatgaat gctcagctta tttcccaaaa caagcggtgc
     6601 tacaaaacgc ccttcgatgg tttgctcaat cataaagata acaagcacct taaccaacat
     6661 aaatgggcct tgtaccatag ccataatcac aacaggtatc atggcaagga aacttcctaa
     6721 gtaaggtatc atgttaagaa agccagcaat aatcccaaaa gtgatggcat atttcagtcc
     6781 cacaaggcta aacatgatag aaaacataaa gccgacaaca attgcaaccg taacctgccc
     6841 ttgcacatag cctgataatt gcttgttaat atctcccaag actcgaacca taggcacccg
     6901 taatttgaga ggtaagacat tcacaaggcc atttttcatg tggctactgt ctcgtaaaaa
     6961 ataaaagaga ataaagggcg aaataataat agccacggta atccgagcaa tggcaccagc
     7021 aaaattacca gcccagtcaa tagcattttt tgaaaaactt tgcgcgtaat ccaaagcctt
     7081 ttgacttgta tgggtaagca tgtcttggag ttggggctta tagctgacta accattcatt
     7141 ttcaagaagt ttattggctt cttcattgac cttgcccacg tatttgggca gatcctcaat
     7201 aaaactggta agttgggtct gtaccatggg aacaaagcct gaaatcgccc agacaaaaag
     7261 taaggtaatc aaaccaaaaa caataaaaat agaggtggta cgattcgggc ccaagtgatt
     7321 aataaggtca actaagggtt tggtcagata atacagaatg gtcgaaataa ccaagggcaa
     7381 catgatgacc gcaaaaaaag aaatcactgg cataaataaa aaagagattt tagtaaaaac
     7441 aaaaatcgtt aaaaaggcta aaagtgttat tactaaagcc atggtagctt gattatttaa
     7501 aaaccatttg taaaataagc tatctgttct agacttttca ggtattaagg gcattaagat
     7561 agggttcctt tctttgggaa aatgataggt tttactggta acctgggtaa atcaataaaa
     7621 ggtcacagat ttatccatga gttggttgtt ttggtcatag gtaaatttgg cagagaaaaa
     7681 agaacggtct tctaaaatcc atttaaaaat gtcataatca ccttcccaag ttggcttttc
     7741 caacacttga tcgtaaggta cccattccaa ggttccttct cgtgactctt catctgaaat
     7801 gaggtctcct tcaaatcctg ttactttaaa aacataggta taccagtcat gaccaggggt
     7861 aaattctgga aaagtaatga ttcctttaaa ggccatctct gtaacagtca aatgggtttc
     7921 ctctaaaatc tcacgacggg cacactcatc tggggtctca ccagcctcga gcttaccccc
     7981 aactgaaatc cacttgcctt tgtggacatc attttctttt ttattgcggt gtaataatag
     8041 caaagaatcg ccattatcaa tgtaacaaat ggttgctaat tgagtcatct atctctttcc
     8101 tttccatctt tgtttctatt ataccaatct ctagaaaata tgctatcatt ttatgagtca
     8161 aagtgtgaat acttagtcac gctcaaaacc ttctaaagat gccttaaaaa agtgtagata
     8221 agagcctaca atgaaaaaca tcaatttaaa ctatcaaaag aaccttgtca tatcaattat
     8281 cgttgatatg acaaggttct ttaatgtttt atttaatcac ttcttgagtt ttagcatact
     8341 tggcttctac agcatctttt tctgctttcc accatgtctc attttctgtg taccacttaa
     8401 tagtttcttc caaaccttct gaaaagtttg taaattgtgg ttcccagccg agttcttcac
     8461 gcaattttgt agaatcaata gcgtaacgaa gatcgtgacc agcacggtca gttacgtgat
     8521 cataagcgtc ttttggttga cccattttct caaggataag ctcaagaact tccttgttgt
     8581 ttttctcgcc gtcggcacca ataaggtatg tttcaccgat acgaccctta gtcaaaatag
     8641 cccatactcc tgtagaatga tcattagtat gaatccagtc acggacgttt ttaccttcac
     8701 cataaagttt tggtttgatt cctgccaaga tatttgtaat ttgacgtgga atgaattttt
     8761 cgatgtgttg gtatggtcca tagttatttg aacagttcga aatggtcgct ttcacaccga
     8821 aggaacgtac ccatgcctta acgataaggt cagaagctgc cttagttgat gagtaaggtg
     8881 atgatggatt gtattttgtt tcagcagtga atttttcacc tggtccttca ccctgtcctg
     8941 gaaggtcttc acgaagtgga agatctccat aaacttcatc agttgacacg tggtggaaac
     9001 ggatatcgta tttacgagct gcttcaagca aagtgtaagt tccgataaag tttgtatgga
     9061 taaatggact tggatcttcc aatgagttat cgttgtggct ctcagccgca tagtgaacaa
     9121 taacatccgt tttggcagcc aatttatcta ccaattcagc gtcagcgata tcaccaacaa
     9181 ctaactcaac acgatcacca agaatagctt caatgttagc acgattacct gcatatgtca
     9241 atttatcaag gacagttaca tgaacatctg ggtggttatt gtagacatag tgcacaaagt
     9301 tagatccgat gaaaccagct ccaccagtta cgataatatt tttatacata agatataaag
     9361 ggacctttcg tttccgaaaa aatctattaa aagtaatgac tctaacaaag acgttttagg
     9421 cctaagaaaa catcgctttc taagatttaa gtcccatgtt cagctcaaag agagaaactg
     9481 aactttcctt tcatcatttt tagttgttac ttgttacctg aagtagagaa gaataactcc
     9541 cctcatatcc acctcaaatg attaatccca atcatctgag tatgttgttt ccctataggt
     9601 cttttggttt cagtggtttg acatcactaa gaagaggatg gtttttatct gcttcagaaa
     9661 cttctgcagc tgctagattt tcccaagtaa tcccaagact tgggtcagca tagtttacaa
     9721 aagcatactt aggtttcaag tcaagagccc agtagtcatt gacaagataa ctgtaagaga
     9781 cagtctctga aagaacttga aagccattag caacccctct aggaacaaac attccttttg
     9841 aagcatcaat cactgtctgg tagacgtttc caaaagtctc tccctcacga agatcaaccc
     9901 aagctcctaa aaccttgcca tcatcagcaa ctgagatgta tttatcccaa ggttcagcat
     9961 gaagtccacg cagcacatgc tgacgtgaaa aagaaacgtt gttttgtagt tttccttcct
    10021 caaaaaaacg ttctggaaag ccaattggca acattttttc tttttggaaa ttttctttaa
    10081 accagccacg attatcccca cgaacaggaa tatcaaactc tagtaagcct gggatttctt
    10141 tgatttctcg gcaagccaat ggtttgtcaa aaaaagtttc tgtcattaag cttctccaat
    10201 caaacgaagc aagtattgcc cgtattcgtt tttctttaaa gattgcgcca atttatggac
    10261 atcttcttta ctgatatagc ccatgcgata ggcaatttct tccagatttg ccacttgagc
    10321 gttttgcaag cgttgaacag tttcaatata ttgagccgct tcaagtagac tttcatgcgt
    10381 tccagtgtct aaccatgcaa aaccacgccc catcaattca acggagaggt caccacgttc
    10441 caagtaagcc ttgttgacgt ctgtaatttc caactcacca cgcgcgcttg gtttaatgtt
    10501 tttagcaatc tctaccacgt cattgtcata gaaataaagt ccagtcactg caaagtgaga
    10561 cttaggcact tctggttttt cttcgataga gatagcattc atgttctcat caaattccac
    10621 cactccaaag cgctcagggt ctttcacttg ataaccaaaa acggtggctc ctttttcttt
    10681 ggcagctgcc ttttgaagca ttttagtgag gccattaccg tggtaaatat tatctcctaa
    10741 aataagagca acacggtcat caccgataaa ctcctctcca ataatgaaag cttgtgctaa
    10801 accatctggg cttggttgtt ccttatagga taagctaatg ccaaattctg acccgtctcc
    10861 tagcaattct tcgaaacgag gaagatcttg gggagttgaa atgattaaaa catctttaat
    10921 ccctgccaac atcaaggttg acaatgggta ataaatcatt ggtttgtcat aaatgggcat
    10981 caactgttta gatgcggcac gggtcagtgg atacaagcgt gtccctgaac ctcctgcaag
    11041 aataatacct ttcatagtag tgctcctatt cttctatata ccctatcatt ctatcatttt
    11101 ttgaaagcag tgtcacgctt taccagtaga ccgcaaaagg taaggctcag gagaatagtc
    11161 gctaggcgtc aaaagtcctt cgtgtcctag caataattga gctaattcat agccaatcaa
    11221 aggtccaact gttaatcccg atgaccctaa accactagct gtataaaggt tcttcaatcc
    11281 tgaaacctga ccataaaaag gagaataatc actggtataa gctcttattc ctacacgaca
    11341 cgttttttga gtagcttctt ttaataacgg caaataagta agagcttgca tttcaagttt
    11401 ttctaaaacc tgccaatcag gctccaaatc ataaccttta tcattttcgt gactcgtacc
    11461 aacagaaatc ttaccttggt taaaaggaat aagatctatt tcaccttctg gcataacaac
    11521 tggataagtg tcgctgatga tgtgatgaac gtcataatcc aagagttgtc ccttttgtgg
    11581 tcgcacatca acctgatagc ctaaaggcct caataagtca ggtagccatg ctcctgctgc
    11641 cagaatgacc tgatcaaaat aatgaccagc aatctcataa ccacttcctt gctgtttcag
    11701 agtgactttt tggcgaataa ctggataacc actagccttg agtaatgtct cacataaagc
    11761 ggctccctcc actctagcag ctcctgaagc gtacagacag ttatcaaagc caatcaatcc
    11821 tttaaaatca ttccccagtt ctttacgatt tttaacggct aactcaccaa taatcggtga
    11881 ttctaccttt cttgctaacg ctaattcata aagatctctt agtttttctt cctgcttttt
    11941 taaaacatag atgccatttt gctgataaaa atctgttgca aaaccatctt ctttgaggtc
    12001 attgattaat tgctgataaa agtccgctcc taaacgagcc atgcggtacc aaactttatt
    12061 gcgacgcttt gaaaaccaag gactaataat accagcagct gccttagtgg cttgtccttg
    12121 accatggtca aaaatggtaa cttctttttg accactttgt tgtaaataat aagcggcggt
    12181 tgatcctaca atccccgccc caataatggc tattttcatt cctggtatcc ttttatctta
    12241 ttttaagacc ttaacagcct ataaatggct aaatggattg gtcgaggctt tgcttgaaat
    12301 aatgctgaca tcccaaccgt tctcttcttt ccacccttgg agtttctcct ttaatttctc
    12361 cgtaaaaagc acctcaatat gatgccccgg gtcaaccgca aatagtcctt ctgtcagcat
    12421 ctcctgtgct gtatggtaat agatatcccc tgtaatataa acgtctgcgc ctttttgcac
    12481 agcatcctga taaaattcac caccacttcc gccacagata gcaatctttg aaatcaaagg
    12541 gttttcctta tcgtaacgga taagtcgcac ggtatctaaa tcaaacaccc ttttgacctt
    12601 acttgctaac tcttctaacg cttgttcttt aactgttcca atacgaccaa tgccaaagcc
    12661 ttctttggtt tcagacaagt aagttgcttc cttgatttct agcaggtcac aaaaccaatc
    12721 atttagccca cctggtacaa tgtcaatatt ggtatggctc acatagacgg aaatgtcatg
    12781 cttgaccaaa tctagaagga tatcacgctg aggggatgaa accagatctt taagcggttt
    12841 aaagatggga gcatgcttag ttataatgag atcaacttca tttttgatgg cttctgctac
    12901 tgttgactct cggatatcta aagtaatcat aaccttacga atgtctttat ccaatgaacc
    12961 catttgaaga cctttaacgt ctccttccat agataaatca agtgggcaaa aggcttcata
    13021 ggcatcaatt agggttttag ctttcatgaa caatcacctc ttttatttgt tgtatttttg
    13081 tcaagagaag ctgacgctct tgagtttttt cttctgggat gcaggacaag gcataagcta
    13141 acttatccat ttctcgttgc cacttctctt taaaaacgac tgatttttcc tgagaaaggt
    13201 atggaccaaa acgcaattct gtcgcggata aggccttttc accatgctca gcaacgatga
    13261 tttcataata tttgtcattt tcagccatga tggtttctgc aacaatttta aaagcgttaa
    13321 ccgataacca agcccgtaaa tcatcctcac gattgttggg ttgtaaaacc agacgttcaa
    13381 tgccctgcaa tttttcctta cctgcctcta aaatatcagc aatcaaacgg ccacccatgc
    13441 cacaaatggt aatggctgtc acatcatcag cttcttcaaa ggctgcaagg ccattggcta
    13501 agcgcacctg aatatgctcg gcaaggccag actgtgtgac atttttaaga gcagattcgt
    13561 agggacccct aaccacttcg ccagcaatgg ctgctgaaat ctgattagtt tctaccaaaa
    13621 atatgggaag gtaggcatga tcactgccaa catctaataa tttgacacct tttggaacat
    13681 aggccgcaac ttgggccaaa cggtttgata attgactatc catcttgatt tctttctaaa
    13741 acgtaatggt tctattatag caaaattacc tccataaaaa aagaaaacca aaggctaggc
    13801 tttcgatttt ccataagtat cttgatagta cttgcagtaa gactgaacgg gacaaatctc
    13861 acattttggt tttttggcta aacaatggta gcgtccaaaa aaaatcaatc gatggtgagt
    13921 aataatccaa tctttctttg gaattttagc catcaaatct gcttcaatct gcttgacatc
    13981 ggcatctggc gatgaaatat tgagcctctt tgagactcta gccacatgag tatcaaccgc
    14041 aatagctgga acaccataaa cctctgccag caccacattg gctgtttttc ggccaacacc
    14101 cggtaaactt tcaagctctt tgtgggtttt tggcacttga cccttaaaat catcacgaat
    14161 agcctgagca gttttaatga tatttttggc cttattttta tagagtccaa tcgttctcag
    14221 agcattttca acatcagaaa gttcagcaaa agctaagtct tctatttctg gataagactg
    14281 ccatagtcca ggagttacct tattgacggc cttatctgtc gtttgagctg ataaaatcac
    14341 cgcaatcaac aattgaaaag gtgtttccca gtctaactct cccttagcct caggaaacat
    14401 ttgaccaatg atggtcagga cttttgctaa tcttgctttt ccaattctca tgaatcactc
    14461 cataaattca tcgcagatag aaaatcctct gatatcgtca cttgagaaag atcttcgcct
    14521 tctctaacac gtctacgttc ttctacttgt cgaagattaa caataccttc ttttcgccaa
    14581 ttacgtaaga tagcctggat atatttccaa tttgttttgc cgttgaagac agcttctttt
    14641 aaagcttctc gtatcaaatc aggatctgtt ttatcatcac gaagcgtttt ttcaagatct
    14701 tctaactcaa aaggactcaa gaatcgtcct agttcacgtt caaattcatc aactaatcgt
    14761 ttgaaatgat ttggtgtttc ttgtttgtca atttcagttg ccgtttgact gacaaacaat
    14821 tgatctaact tggctaacac aggactcgca tcaaaaataa tttcaatttc tccagtaagt
    14881 tcaattgtcc gcatatctaa aagcccttga ttagtcaaag atgaaatgat tttattaata
    14941 tcagcaactg attttccaag cgcatgagca atttgactgg gtgctaagtc gtctcgcttt
    15001 gtcgtatttt gaagatagaa aaactgccag accaaaaaat catctgagct cttaaaaaga
    15061 tctttgtaat gaaaaagcaa ggcacttggg ataaccaaat tacctgactt ataatgttct
    15121 aaaaaactca taatccctca atcaaaaggc taaaatcgaa tctatagcct ttactacttt
    15181 aaatccccta atcagatgct gattaatgtg tttacccagg aaactgcatt aagactttat
    15241 agtcatagtt cctaatagca tggcgtccat ttaaaccttc taattcaata aggaaggcac
    15301 aaccagctac aataccacca agtttttcaa tcatttcaat agttgctttt actgtaccgc
    15361 cagtcgctag taaatcatcg acaatcaaaa cacgttgtcc aggcttaata gcatctgcat
    15421 gcatagttaa agtatcaaga ccatattctt tttcgtaatc ggcagagaca acatctcttg
    15481 gcagttttcc tggtttacga acgggagcaa aaccaattcc taactcaact gcaacaggac
    15541 aaccaatgat aaaaccacgc gcttcaggtc caacaaccat atcaatatct ttatcacaag
    15601 cgtactgtgc tatttcacga atagcatagc tatatgcttt accgtcagcc attaaaggtg
    15661 agatatctcg aaacgtaata ccagctttag ggtaatcttt gatcgatgca atgtaatttg
    15721 ttaaatccat agttaattct ttctagtggc aaattgccaa atataaaata ctcttcatta
    15781 tatcacgaaa catatttttc gtaaaataag acttctgaca ttattgttta tctgatactt
    15841 cattcgtaac tacctcaata actactgtca actgctttac ttattgatcg tttgatttca
    15901 ccaaataatc atacatctct ttcgggctag ccaaagccat gatttcttga aatttcacca
    15961 attcttttaa gtcttggtaa atgtggctct ctgaaatctc tcgtttttgc gcttgggggt
    16021 taaccgtcat cagcccatcg tcaatcgtca caaaagacaa ctcttcaaaa atttgaatca
    16081 acttaatcag taaaagtttt tctatgttta aatagtgact caactctgtc aatttatgtc
    16141 gtaaatcaaa ttcaggaaac tgatagatgg ttttgtagag cttggcaaac tgctctctgc
    16201 tgccaaatcc tgttaaataa taaggatgtt tcatctgatt tttaaaatag atggcgtcaa
    16261 aatccttgtg aacaaactgg ttgcgccagg ttttgaaatc ttcagggatg tcattaatca
    16321 gaatgactct ggcatttggg tcttcttcaa tagtcggaat accttcagga actttggctg
    16381 tttttgtcct taagtcaaga agttgcactc cgtcaacacg agcatctact aacatgaatt
    16441 ggagactcgt gttcccattc caatggttga cagataaggt aactgctaat tctaaaccag
    16501 tagcttgtcg gaactcttgc agttgacttc cttgaccaaa agccagtacg tcaaaggaag
    16561 ctttgccctg actgacttta aatttaagat ggctctggtc ttgccctatg gtacgcgctt
    16621 gactaaccct tatgtccttg acataaaaga ccggcttttg atgatccatc ccataagggg
    16681 ctaatttatc taaactcttt aaaatatcaa ggctaaggtc gtccaaagac agtctttcat
    16741 caatagttaa cgtatttttg gcagtctgat ctaagccacg ttctatcaca aactgacaaa
    16801 gaaagtctga aagagcttcc aagttgtcaa cgggcagggt cattcctgct gcaccagcat
    16861 gtcccccaaa ggctgtaaat aactcacgct tgccatttaa ggcttcaaaa atattaatag
    16921 cttctaaact tctggccgag ccttttgcaa agccattatc aatggtcaaa acgacgaccg
    16981 tttgtccaat agtttccatg atacgaccag cgacaatccc aagaacacca ggatgccagc
    17041 cagcttgtgc caagacttga acaggttttt gaggatcaac catagccatc gcttgatcaa
    17101 aaatgtcttg gactaaggcc ttacgctctt catttttttt cttaatcatc aaggcaatcg
    17161 cttgagcttc ttggtcatca aagcccgtca gtagctcaat ggctggatta gggtcatcta
    17221 agcgccctaa agcatttaat tgcggagcaa tctgaaagcc aatggcgtct tcattaaaat
    17281 gttccaaatc aataggagac aaggacatca actcctgcaa gcccactctt tcggtgtgtt
    17341 tgagcatggc cagaccattt ttgactaaaa cacggttttc acctgtcaag cttaccatat
    17401 cggcaatggt tccaatagct accaagtcta gacagtctgt tggtaaactt tctagcaaag
    17461 ctgttgccaa tttaaaggca acgccacagc cagctaagtg tttaaaggga taatcagcat
    17521 caggatgctc aggatgaatg atggcaaagg cttctggcaa ttcttcaggc aggctatgat
    17581 ggtcagttac aataacatca acttcctgtt cttgagcata tctaatcgct tcatgtccgg
    17641 ccacgccatt atcaaccgtg ataattaggg acacagcttc ctgctcaata aaatatttat
    17701 agacgctctg gttggggcca tagccatctg taaagcggtt gggaagataa accaaaggct
    17761 ctgctcccat catgtctagg gtttctttga caatagaagc cgacgtcatg ccatcagcat
    17821 catagtcgcc gtaaatgaga attcgttcgc cctcttcaat agcttgacga attcttggca
    17881 cagcttttgc catgtcatgt agcaagtaag gatcatgcag ttgagacaag tccgctgtta
    17941 aaaactcatc taaggcttct tcagtcctta tccctcgatc ataaatcaac tgagcggcgg
    18001 tctgggttag accttttgtc tttgctagct taaagaagcc atcatctggc ttcttgtctt
    18061 ttattttcca gctatatttg gatttaatca tttataatta aatacctttc ttgcaagata
    18121 atcagataat ttagggaaaa gggtgtaaaa ttgatgggtc accgctaaac taaagggcaa
    18181 attcaattct cgtttatttt tcccgataat agaaaccaaa cgcttagcca cttgatttgg
    18241 ttggagagta aatttaccaa cgctttccaa ataatgtcca gacgggtcag cttggtcaaa
    18301 aaacttggtg gcaatgggac ctggattcac ggtggtcacg taaacccctt tatccgctaa
    18361 ttctaagcga agggcattgg aaaatccgat aagggcaaac ttggtggctg aataaatgct
    18421 cgatttggct gacgcaatca agcctgccat ggacacaata ttaataaggt gaccttgccc
    18481 ctgctctgcc attttctgac caatcaagca agcaaagtga atgctcgcta gggtgttaac
    18541 ctgaaacata tcagctattt cttgggcaga aaactcttca aagcctttga aagctccgta
    18601 gccagcatta ttaatcaaga catcaatacg gccatagcgc tggtaaatct gggcgaccat
    18661 tttctcaatg gctactggat tggtaatatc caactcgagg cattctttgt tgtcaatatg
    18721 ctgataacag tgttctaggc gttctttgtt acgtcctaat aaaatcaagc tgtcttcctt
    18781 gggtaactgc ttaacaattg cctgagccag tcctccagaa gctcccgtga taacaatgat
    18841 tctttgtgcc attaaataat cacttcctct aaatcttgta ccattttaac attttcaaat
    18901 atagtggcgg catctttttc catctggcga caatcacgcc ctaaaaagcg agctgataca
    18961 tgattgagca agaggcgttt tgcgcctgct tcatgagcga tttgtgctgc ctgcatgttg
    19021 gtagaatgcc cgtgatttct cgcaatccgc tcgtcaccct taccataggt ggattcatga
    19081 accaaaacat ctgcatcttt agcgagttta acactggcag acgttttgcg cgtatcgccg
    19141 ataatggtga tgattttgcc ttttttaggg gcagaaatat aatctttggc acaaatcagg
    19201 cggccgtctt ccaactcaac gtcttgacca tttttaattt tgccaaagag tggtccaaaa
    19261 ggaacacccg ctgcttttaa ggcttctgcg tctagggttc cttctaagtc tttttgaact
    19321 actcgataac ccatgcaaaa aatggtatgc gccagacgct ctgcatagac ctcaaactta
    19381 tctgtttcca ttattttacc taatgatttg tcatcaaatt catgaaaatg aatctgataa
    19441 ggtacacgcg ctccagaaac ttttagacta gttaacacgt aagttttaat gccaattggt
    19501 ccataaatat caagatctgt ctgttcttca ctagcttgaa aagaccgact tgataaaaat
    19561 cctggtaatc caaaaatgtg gtctccatgc aaatgagtaa tgaaaatctt tcttattttt
    19621 cgtggcttaa tcgtcgtttc taaaatttgt ctttgcgttc cttcaccgca atcaaacatc
    19681 cagacttcat tgatttcgtc tagtaatttc aaggcaagac ttgacacatt gcgctgcttg
    19741 gctggttgac cagctccagt tcctaaaaat tgtaattcca ttcaatctat tctttctatt
    19801 gggtgatgta aatcataaat tctcgttggg caaaatcata atacttttga ccagaaaatg
    19861 tttggctaag agcccataac tcctctacat taaacccctt aagcatggtg ataccgtttg
    19921 ccagacggta aatcttcgac aagagtgtgt catcaggtgt aatgtcttca cattctcctt
    19981 gctcaaactg cttagcctgc attttaagct ggcctttgtc ctcataaacc atatattgtg
    20041 ggaaaatttg tgttaattca aagaagagtt cgggtttctt aggctctgct ttttcagaaa
    20101 ataccaatgc aacttcttgg tcattttggt aagcaaaacc ataagctttt ccagacaaat
    20161 tgaggcgtac aaagggcttt tcttcctcaa aagatggttg gtcagtaaaa agccccaaag
    20221 ccttagaaag attaaaataa taatcagttg cagcttgcgg tgactgtttc tggtagattt
    20281 cagcaaagta ggcattaata acacttggtg gtggtgtgat aaaagctagt ttttgctggt
    20341 ctgtcaaact ggctaacaga tggtttaggt agttggtatc cagactagta aatccaccat
    20401 aggtttttgc taaatcaata taattattca taaaaatcgt caagtctcca ttgctgtttt
    20461 ggggaaatgt agcccgaaat atcctctatt tcttggtcaa acgtgtagtg gtctaaaaga
    20521 gcaactcgat tcaaatcata tagcttgtac gccttgtctt gatgcacttt gattctaaaa
    20581 ggaacaaact ggtctcgaat ttggtcaatg attaaacgtc tcaagagaat tttgctatcc
    20641 tttgaacggg ctgaaatcct gatatttgga aaagcagtag ctgtgaattg ttctgctata
    20701 tccaccttgt tataaatagc taaacgcgga atattaagca tgtctagctc ttttagaagg
    20761 tttaaaacca ctttttcttg ctcactatga ttgggatcac tcgcatcaat cacatgtaac
    20821 agcaaatcca catatttgct ttcttctagg gttgatttaa aagcagccac taattccgtt
    20881 ggcaagtctt gaataaagcc tacggtgtct gttaaggttg cttgaaattg attttctaaa
    20941 tagagttgct ttgtagttgc atctaaggta gcaaataatt cattggcttc atagtggctg
    21001 tcatctgtca acaagttcat aatggttgac ttgccagcat tggtgtagcc aatcaagcca
    21061 attttaaagg tatctgaacc cacacgacga tctctaattg tttgacgatt tttctctacc
    21121 tgagttaatt ggcgttcaat atcagcaatc tgatgacgaa tcgaacggcg atttaactct
    21181 agttggcttt cacctggtcc acggctccca ataccacctg cttgacgact taacatgatg
    21241 ccctgtccaa ccaaacgagg taacatatat ttcaattggg caaggtgtac ttgtaatttg
    21301 ccctcatggc ttctggcacg catggcaaaa atatctaaga ttaactgcat acggtcaatg
    21361 acttttacct ctaaaacagc ttctagatta gcattttgcc tagcagtcaa ccgattgttc
    21421 acaataactg catcaatctc atcagcttcc acaatcgcct taatctcatc cagtttccct
    21481 gagccgataa aggttttgct gtcgtaacgt tctcgttttt ggctgaaact tgccataact
    21541 ttgacaccag ctgttttggc aagattagct aattctgtca tggacatgtc aaaatgttct
    21601 gttgtctgaa gctcaactcc taaaagaatc actctttctt gctgacgctt tgtctcaatc
    21661 atcaccttta ccaatcctcc aaattccgta aattctatta taacatatct tcaacagatt
    21721 ctgctaattt tgcgtcatga cttctctttc tgaccaagaa aatccctgac cctatcatgt
    21781 actacctgtg ggtaatcagg agccgttatg gcagtgaagc taacagccat tcgattgcgg
    21841 aaccaagtta gctgtcgctt ggcaaaacgt ctcgtgtttt gttttaattg atcactagct
    21901 tctgccaaag tcatttcacc tacaaaatag gggaataatt ccttataacc tatgccacga
    21961 ctagcctgaa cagtcgggta atgctcatat aaccattttg cttcttccaa taagccgttt
    22021 tcaatcatac gattcacgcg ctgattgata cggtcataga tgacttggcg gtcatcattc
    22081 aagccgataa taagcggctc ataagccgtc tcggcattct ctaattcatc agcaaactga
    22141 gccaattcaa gggctcggat cgcccgtctg cgattcacct gctcaatggt aatgttattg
    22201 acttgcaagc gttcatacaa gtcgtgatcg tccaattgct ccaactcatt ccgataggct
    22261 tttaccgcct cttgatcaac ttgacctcct agatgataac cttcgagtaa actttgtaag
    22321 taaagaccag ttccacctac aataattggt aatttcccac gactaacaat atctgaaata
    22381 gatttttgag catcttgaac aaaatcgtag gccgaataag actccgtcac ctcacgaata
    22441 tcaattaagt gatgaaccgc tgcttcttgc tcttcttgag tggccttggc tgttccaata
    22501 tccaactgtc gataaacttg ctggctatct cctgaaataa tttctccatt aaaagccttg
    22561 gctaaactaa tcccaagtgc tgtttttcca accgctgtcg gaccaacaat cacaactatt
    22621 tttatttttg tcattttctt gtctttctat tagaaaagcg tgtccaaaaa cgccttttac
    22681 ttgaaaatta gcttattttt cgctaccata tattataaca taagattaag gaccactgag
    22741 gtccttcact agaaatggag aataatcatg gttaagaaat atcaatttgt taaaggtctt
    22801 gctactggcg tcctagcaac tgctgctact gttgctggtg ctgtctttgc tgtaaaaaaa
    22861 acaatcattg accctgaaga agaaaaagct gctttcattg aagaaaaccg caaaaaagct
    22921 gcgcgtcgtc gtgtagctcg ctaacgtgac aatggatcaa tttaaaagag actagcacat
    22981 taaagtgccg gcctcttttt tagtaatctc gataactagt tagtagtaac tgtctcttga
    23041 tgagccaaga tgttagctgc tttacttatt ttgaaataga aatctcaggt aagccccata
    23101 aacataagtg actaaagctg tcgccaacaa tacctctcct agcaaaagaa cctgccaacc
    23161 taaaccttgc caacctaaaa aagataaggt catttttaag gaagtggcac taatcacaaa
    23221 cggaaaggta aaagctgaaa aacctgggtt aaagggacga ttgagtaagc gaggaagctg
    23281 tacaaccaca aaagcatata acagttgtga gctgacgaga agaaagataa ccattcctac
    23341 ttgtggtcta ggaaaggttg ctaaataaga cgctgaaagt aaggacagag gggcacaaaa
    23401 cgttgaaata ttgggcatta ctgcttgacc tagaccaatc ccataagtct ttttggccat
    23461 aaaaggtaaa atcacagcag ttaagagaag acaaacccaa aaaatcacct gtcctaataa
    23521 aaactgccta ctagcaggtg ctgttaatgc cgccattgca attccaacaa aaagcacgga
    23581 ccaggaagga aaaacgttat cccatgaaaa agaaaagaca aaacgatact ggtaataagc
    23641 aatcaggaca agatttccca aaaagaatag ccaccaagtg agaaagccta accaacaccc
    23701 tcctgtcact ttgagaaaga gtgaagacaa caacatccct gtcataaaaa aagttggaaa
    23761 aacagaggca attagaggtt gtcgtaactg cattttggta tcgttaaggt tcctaaccat
    23821 gccaacaagc aagataccat agataaaaag agctgccaga attcccaaat aattaaaaat
    23881 cgaaacataa gtagccaaca aattgccaaa tgacaacgtt cctaatgcca atcctgacat
    23941 gaccaatggt ggggttttaa ggtgtttcat aagtgtcctt ttctgcctat taacagctat
    24001 ttttagtgac ataatcttgt ttattttatc acatttcgag catttttgac accacccgcg
    24061 aaagaaaatt taaggctctt gccattgttt ttttacattc tcgcaaaact aggaaactgc
    24121 ttaaaaagct aaggagtgac cactcttctc tagaaaaatg aaagagtaga gaagacttgg
    24181 tctgatcttt acttcttctt tttgatttag tgagctgcat taagcacttg ttgaacagct
    24241 gaatcttcca ccatttttgc cataaaagct gccagatgcg gataattctc gtaagatttt
    24301 ggtgtttttt gagaccatag cgccatggcg taagcataag catctgcaat ggtttgttga
    24361 tctcgataaa catgcccact ctccccaata agactatcta aatgcgtcat agcaatatcc
    24421 atccgcttgt aagaagcttg tttgactttt tcaagcgctt gattgtcttg agaaatagtg
    24481 tagcgatgag ggttgatcat tggcctaaaa acaaggggaa aatcacctgt taagaagtcc
    24541 atgatttcgt tgaaccgact ttctgccaaa agattatctt ggggaatgag ctgagatttc
    24601 agggtttgtt tcgctataaa gggcaagata atacctgcct gtgtgacaat ttgaccatca
    24661 tcaagctgta aagcttaaac cattcccaaa ggattgatgg taaggcagtc ttcagaatcc
    24721 agttttacct tctctatctc gtaatacaga aactcacaat tcttttgaaa aggtgctaga
    24781 cagagttggt gttgacgtct tcgctgttga tggctctgca tgacaaaatg agcttggtgt
    24841 ccacgttcac ttgtatcttg ttgcaaagtc tttgcaattt ggtctcatca tctgtatcac
    24901 aaaaaacaaa ccagtttcct gatttgtttt gagatattag gcacctacaa attctggcaa
    24961 ggattctcca atagcttcta aacgttctgc ccattcttga cgtgataaac cattttcttg
    25021 cacatagcga ttacgttcat gtgcacgaca ttcaggtgag catcctcgaa catactttgt
    25081 ttcgttttct tctgaagcaa aaatttgttt gttacaaaac ggatttgcac aattgacata
    25141 acgttcacaa ggtgttccat caaaataatc tttactaatg acagttggat taacatgatt
    25201 aattggcacc gagatacgat catcaaaaac atacatcgca ccatcccaaa gttcaccttg
    25261 aacttccgga tcttttccat atgttgcaat accaccgtgt aattgtccaa catctttaaa
    25321 gccttctcga accatccaac ccgagaattt ctcacagcga acaccacccg tacagtacac
    25381 aacaacacgt ttttccataa acttatcttt gttgtcacgt acccattgtg gtaactcacg
    25441 gaaattgcga atatcaggac gaattgctcc acggaagtga cctaagtcat actcataatc
    25501 attacgcgta tctaaaacaa cagtatcttc atcaagcaag gcttctttaa attgtttagg
    25561 atttaaatac tcacctgttg tttccaaagg attaatatca ctatcaaagt tattgtcttc
    25621 taacccaagg tgcacgatct ctttcttata acgaacaaac attttacgga aagcttgttg
    25681 attttcctcg tcaatcttga accaaagatc agcaaaacgc tcatcgctgt ggacccaatc
    25741 catatacttc tgagttgttt cataatctcc agaaacagtt ccattaatcc cctcatccgc
    25801 aatcaaaata cgacctttaa gcccaataga tttacaaaat tctagatgtt tcgcagcgta
    25861 ctcttgcgca ttttcaattg aaacatattt ataatagagt aaaactctga ttttttctga
    25921 cattttttct ccttcattgt tattcagtta cttcctatta tatctaggaa aaacaagtct
    25981 aggcaagtca tttgtttgtc tttttttcac aaaatagatc tcaatttatt tttgatgaga
    26041 tgagatgcaa cccattactc ctttaagcaa atcattagaa gctttattta gaaaatgcta
    26101 agataaaaca aggaggccaa aatgacttat gaactttgtt tagaatatgg gacttatccg
    26161 ttgtcacgtg ttgatgctta ctggggagaa gatcaaaatc ccccaacatt cattcaagaa
    26221 gatcgactgc tttgccataa actagaaact atgaatcacc tgttccatga tttatttgta
    26281 actattgaat cacaattcca ttatgttggt tttaacatgc ctgaaaaaag agcgcagatt
    26341 cggatactat atcaagaagt agctactata ttaaaatcca aatataagga ttatccaatt
    26401 aagattgaga cgtttcttct ttaaaaatct aatactaaaa aactaactgt gcttagacag
    26461 atgacacagc tagtttttta ggtaaaactc ttcttaaatt ttaaaacgtt tcgaaaaatc
    26521 actaaatgct ttaatagcac ttgctaaaaa tggtttcacc atctcatcat taattaacct
    26581 tgattactta caatcttatg aatctgagtc aaataaaatt caggctgtgg cattacagag
    26641 acatttaaaa cctatactca tcgttttcaa ggtcagaaag agaatgattt tgaaaaggtt
    26701 cgtcaactct tctagataat tttggacaaa ttttgatcaa gaaacaaaaa gagcctatca
    26761 aataaggctt ttttatatga tttctatcca ccttgaggga atcgaacccc catctcaaga
    26821 accggaatct tacgtgatat ccattacact aaaggtggtc acaactttgt caataccctt
    26881 atagtatatc ataaaatgaa ataatatgaa ataacttttc taaccagaag acaataaaaa
    26941 gttgaggaaa acctcaactt tttagattta ttacaattca atatcaccga aaagatcagc
    27001 cattgagaat ccagtttgtg tttctgggag ttcgtagtca cgtcttgatt cacgttttgg
    27061 acgacgtggg cgtgattgac gtttttcttc tttgttgtct ccttcagctt gcgctgggcg
    27121 ttcttcaaga gctttgattg ataatgatac gcgctcatca gctgcattca cttcaagaac
    27181 tttaactgtt acttcttgtc ctacagaaag tacatctttt ggattttcaa cacgtttgtg
    27241 tgaaatttgt gaaatatgaa caagtccatc aatacctggt aatacttcaa caaaagcacc
    27301 gaagtcagtc aagcgtttta ctttaccttc aacaacatca ccttgagcaa gtttttgttc
    27361 aacgccgtcc catggtccag gtgttgttgc tttaagtgaa agtgacacac gaccagcttc
    27421 ttcgtcaatt gaaagaactt taacttcaac ttcttcacca actgaaacaa ctgatttagg
    27481 tgacacgtta cgttcgtgag acaattcagt cacgtgaaca agtccgtcaa caccaccaag
    27541 gtcaatgaaa gcaccaaaac ttgttaaacg cgctacagta cctgtaacga ctgcaccttc
    27601 tgaaatctta gagaacactt cagcacgagc ttctttagcg gcctcttcga taacttcacg
    27661 acgtgatagg atgaaacggt tttctgctgc atcaacttct ttgattttag catcaaactc
    27721 ttgtccaaca aatttttcag tgttgcgaac aaaacgagtg tcaatcattg aagcagggat
    27781 aaatccacga agtccttcaa attcaactga aaggccacct ttaacagcac gggtaccttt
    27841 aacagtaaca acttcgcctt cacgaccaac aagtttgtcc caggctttac gagcttccaa
    27901 acgtttttta gatactagga aagtaactgt atcagtatct ttacctacta cttgacgaag
    27961 aacaagtact tcaactgtgt cgccagcttt aacaaagtcg ttaatatcag catcgcggtc
    28021 gttagtcaat tcacgaagtg tcaagacacc ttcaacacct gttccttcga taacaacgtt
    28081 tgcttgaccg ttatcaacag ttaaaacttc cgcagtgaca acatcaccag ggttcacttc
    28141 gctaacactg tttagcaaat cttcaaattc attcattcta aaaaatcctc caacaaaagc
    28201 tagccaatgc tagcttttga taacaatata ttttctcaag gtaacccgca acgacaacaa
    28261 ctcttatctt tgacggtctc agggagcacc tgatacctct gactggggta gctggatt
//
LOCUS       DAUGJR010000023        27991 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUGJR010000023 DAUGJR010000000
VERSION     DAUGJR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27991
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.023"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            45..1217
                     /gene="sda1"
                     /locus_tag="VH800_001025"
     CDS             45..1217
                     /gene="sda1"
                     /locus_tag="VH800_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase Sda1"
                     /protein_id="HEQ8362101.1"
                     /translation="MSKHWRHLIIHSALTILATLFLGILPITENTSSTIYAESGTISN
                     NWSIEQHPNYYHVEGKAQLDIKNFPELYRTTERVYKKSGQSTKPVTVSNIHYSVLDGY
                     GRSGEAYGIITKDMIDMSAGYREKWESKPEPSGWYSYFFKNTNQRATESDYKHSPKNV
                     SKISNNIKASILLSNGNVRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNNDRK
                     GGMQYIENKVLDHIKRNPKVHVYYKATPVYQGSELLPRAVLVSALSSDGFIDETVRVF
                     NNVAGFNIDYQNGGLLSSTADVDINNVEENEIETTDDEIEEGIENEPDTDALKKDNKD
                     TSLQDTVYVASNGQSDVYWYNKDSMPKTVNLEKVVEMSEQVALTRGKHHSTQENIE"
     gene            complement(1333..2529)
                     /locus_tag="VH800_001026"
     CDS             complement(1333..2529)
                     /locus_tag="VH800_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8362102.1"
                     /translation="MTFLDNIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFNTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYQ
                     SVVGETDYKKACHAIKDAGYATASGYAELLIQLIEENDLQKWDKEILTNQKEVTMTTA
                     NEIVKYCVDLANSGMGVDKDGAYGTQCCDLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHAHQTVDTAPQNSDTIVETPKSGTFTLDVVEINIR
                     RWPSLASEVVGSYKQGDTVSFDSEGYANGYYWISYLGGSGMRNYMAIGITDKDGNIIS
                     LWGKLN"
     gene            complement(2640..2825)
                     /locus_tag="VH800_001027"
     CDS             complement(2640..2825)
                     /locus_tag="VH800_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362103.1"
                     /translation="MSKWFKKVGIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKDEE"
     gene            complement(2822..3121)
                     /locus_tag="VH800_001028"
     CDS             complement(2822..3121)
                     /locus_tag="VH800_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362104.1"
                     /translation="MHFDLLQAGAAAAALMSVFGLWKAVVTPFKKAMEANEFAMAQLK
                     DSLKELAYELKNLDRDREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            complement(3132..3752)
                     /locus_tag="VH800_001029"
     CDS             complement(3132..3752)
                     /locus_tag="VH800_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362105.1"
                     /translation="MRNWKVTGNYPQWDGTGAVVDTQVIITDDRGAVISEKVKKDLRT
                     ANDAEIIEAALEEFKKTAYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHVLTSGGKIDPDIYKGMLELIEPAKKGEYKEHDIFTVVDADKDTD
                     GVAGEGNLVFVYVNDKFTYDAQTLKDLEELEDKVTVIKYADLVKQD"
     gene            complement(3755..3916)
                     /locus_tag="VH800_001030"
     CDS             complement(3755..3916)
                     /locus_tag="VH800_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362106.1"
                     /translation="MQEKLLGKIINDLTLKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            complement(3925..5832)
                     /locus_tag="VH800_001031"
     CDS             complement(3925..5832)
                     /locus_tag="VH800_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8362107.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFKADGDTKSVKLANNKCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGSGGSTGLFKNLEGALSQLKELNLELTDTVNSQ
                     LWAKIKLTTNGMLREYHRDNITTEIVESANGIATRISEDTDKKLALINETVSGIRRDY
                     QDADRQLSSTYQAGINGLKATMANDKNDLKAVIQATAQGLSQKYDDEIQQLSAKITTT
                     SSGTTEAYESKLADLRAEFTRSHQGMRTVLESRISGLQSTQQSTAYQISQEIKNREGA
                     VSRVQQDLASYQRRLQDTEKNYSSLTQTVRGLQSTVSAPNRGLESRVTQLAGLIEQKV
                     TRGEMESYIRGAGDSIMLAIKGKLPQSKMSASEIVSAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIEHTIT
                     SLLEGKVIRARNGAMMIDLNNSTIDFNSDASINFNSNNNALVRKSGTHTAFVHFGNAT
                     PKNFTRSALYASIGITSSGDGINSASSGRFCGARFFRTASGYEHTASVDQAEIYGDTI
                     IFADDFGINRGFKMTPTGVNTLVDINKMYYAIVALARCWKHLQNVGWDTTHPNFTSAI
                     MNEHSNYMTGI"
     gene            complement(5843..6478)
                     /locus_tag="VH800_001032"
     CDS             complement(5843..6478)
                     /locus_tag="VH800_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362108.1"
                     /translation="MAVQEIPDTYFYRLDSQSIDGTLLQKASLVVDQFYIKIDDYYSF
                     YTDQDVDVYKIISSTQADVYKANKYNYQSLSKPDTSVQKPSAAMGLYQSITIDGLPIA
                     RVICNNQVIWSQSAEPQEVYNITAYVDANVSKLNDYAVIDYNQDFATYGVVWHRVDKV
                     AVEVDGKIVAKLQKPVRTVAGGGAMLSIETWTYPFDGIDKYKNPTFKISQH"
     gene            complement(6478..7533)
                     /locus_tag="VH800_001033"
     CDS             complement(6478..7533)
                     /locus_tag="VH800_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ8362109.1"
                     /translation="MTLEERIPIKVLFDRKDAAEWQKLNPVVDDGELVVELDTHRLKV
                     GDGKLNYNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTSIA
                     DITKVGETLTITLSDDTQKTFSIPNGQKGDRGKGVESARVDEEGNLFVKFEEESEKLV
                     GNIKGQKGDKGDSLKFEDLTSDQIAQIKAKDVDLSAYATKAELKEIDVSKQLADYLSK
                     AEANSTYAKASHKHSLSDITDLNLDRYATKIELQNKASTYHRHRTSDIDGIDEYLKQT
                     DLPQDIVKQSDIRDVVRNAQLSGYVRLADIQYQLNNIGKLKDVATGQYLSVRVVDKGK
                     VPYNTSGLIVFERSGGK"
     gene            complement(7530..9512)
                     /locus_tag="VH800_001034"
     CDS             complement(7530..9512)
                     /locus_tag="VH800_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8362110.1"
                     /translation="MITFLDHRDIEYGAISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLMRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINRRTDKELEEFRETL
                     KNLALPEEAIKKITDAIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEIIGTDGKTRY
                     NKNLLVGNPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLNKVAITLIQANN
                     KGLKLVLTPTKAKMEPQTFEVTKDKQSIEVYPLSYKGVLTGDWYKSKQIDLTASEGQI
                     LALDMAYKAVVDAKGATITAKQSSNPKIILDGRRDR"
     gene            complement(9522..10364)
                     /locus_tag="VH800_001035"
     CDS             complement(9522..10364)
                     /locus_tag="VH800_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8362111.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(10376..14758)
                     /locus_tag="VH800_001036"
     CDS             complement(10376..14758)
                     /locus_tag="VH800_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEQ8362112.1"
                     /translation="MPGTFDGSIFADIGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVDIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGRQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVVQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSALSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINTVLGDFAHTGELSGQAFDNLKAKITSLAPKVIALWA
                     VMNPASAIATIMPLLSLFGKVGLALGSLGASVGVFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IDQLLNTAVTKGPSIIQGLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQ
                     LITSLVQGIGQNATSLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIGSFGNSLQANLPSIISHGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIVQSAVQIIQSLVSGLTQALPQIIAAG
                     IQLVVQLAVALIKGLPQIISAGIQLITGLGKAMLEAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATAMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFA"
     gene            complement(14773..15006)
                     /locus_tag="VH800_001037"
     CDS             complement(14773..15006)
                     /locus_tag="VH800_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362113.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            complement(15081..15536)
                     /locus_tag="VH800_001038"
     CDS             complement(15081..15536)
                     /locus_tag="VH800_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362114.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            complement(15590..16189)
                     /locus_tag="VH800_001039"
     CDS             complement(15590..16189)
                     /locus_tag="VH800_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8362115.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQISESAGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            complement(16201..16560)
                     /locus_tag="VH800_001040"
     CDS             complement(16201..16560)
                     /locus_tag="VH800_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362116.1"
                     /translation="MDYSPETLYLKKVKNRLGALGIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARLLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            complement(16564..16908)
                     /locus_tag="VH800_001041"
     CDS             complement(16564..16908)
                     /locus_tag="VH800_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ8362117.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQRLLHYRVVSPALYSIYLELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            complement(16905..17183)
                     /locus_tag="VH800_001042"
     CDS             complement(16905..17183)
                     /locus_tag="VH800_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362118.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            complement(17194..17550)
                     /locus_tag="VH800_001043"
     CDS             complement(17194..17550)
                     /locus_tag="VH800_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ8362119.1"
                     /translation="MGDKQLIDDIKLFIGISKDDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            complement(17562..18449)
                     /locus_tag="VH800_001044"
     CDS             complement(17562..18449)
                     /locus_tag="VH800_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ8362120.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAESIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            complement(18462..19031)
                     /locus_tag="VH800_001045"
     CDS             complement(18462..19031)
                     /locus_tag="VH800_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8362121.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLTTTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            complement(19187..19453)
                     /locus_tag="VH800_001046"
     CDS             complement(19187..19453)
                     /locus_tag="VH800_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362122.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            complement(19456..19644)
                     /locus_tag="VH800_001047"
     CDS             complement(19456..19644)
                     /locus_tag="VH800_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362123.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            complement(19675..21120)
                     /locus_tag="VH800_001048"
     CDS             complement(19675..21120)
                     /locus_tag="VH800_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ8362124.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRRDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFNCRTTLIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNG
                     HKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDRVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            complement(21080..22612)
                     /locus_tag="VH800_001049"
     CDS             complement(21080..22612)
                     /locus_tag="VH800_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8362125.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYNIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            complement(22628..23905)
                     /locus_tag="VH800_001050"
     CDS             complement(22628..23905)
                     /locus_tag="VH800_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8362126.1"
                     /translation="MTIKQRPKINIVIKYPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            complement(23895..24347)
                     /locus_tag="VH800_001051"
     CDS             complement(23895..24347)
                     /locus_tag="VH800_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEQ8362127.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            complement(24437..24853)
                     /locus_tag="VH800_001052"
     CDS             complement(24437..24853)
                     /locus_tag="VH800_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEQ8362128.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            complement(24850..25041)
                     /locus_tag="VH800_001053"
     CDS             complement(24850..25041)
                     /locus_tag="VH800_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362129.1"
                     /translation="MKIEFFLKQGPTKSVSNYGEICIDEVIGAMKNNDVIALNGKNNA
                     VIIPKQNISHVIIHKEVTG"
     gene            complement(25031..25882)
                     /locus_tag="VH800_001054"
     CDS             complement(25031..25882)
                     /locus_tag="VH800_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEQ8362130.1"
                     /translation="MEIKCGNCLELLAELTDGLIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASQKLTKNGGMIIFNDWKNLGDIARHCEKNGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGVWVVRKKSKWVFNRKSEKYDRPEYRYPVVAGAEKTQH
                     PTQKPVALMKDIITRHTTKGAVVLDPFMGSGSTGVACLLTGRDFIGYELNKDYFNIAN
                     KRIAELTGNGGVGMNIIHRMENGIDAVGDLTTYAVPCCPECKNETYSQKHCPFCGENL
                     MEVANEN"
     gene            complement(25891..26157)
                     /locus_tag="VH800_001055"
     CDS             complement(25891..26157)
                     /locus_tag="VH800_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362131.1"
                     /translation="MTEELIKPLLEEIKRKDDRLYMQSNVIAVLMTAVIMLLMISIAL
                     QNHYEPQITGLRTQLSRTQKQLKRASEDRARQTKRIAELTGNGG"
     gene            complement(26154..26321)
                     /locus_tag="VH800_001056"
     CDS             complement(26154..26321)
                     /locus_tag="VH800_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362132.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLKFWNSCEAT
                     VKEKYTREWKK"
     gene            complement(26322..27644)
                     /locus_tag="VH800_001057"
     CDS             complement(26322..27644)
                     /locus_tag="VH800_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ8362133.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKSTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDFERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            complement(27641..27916)
                     /locus_tag="VH800_001058"
     CDS             complement(27641..27916)
                     /locus_tag="VH800_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEQ8362134.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
BASE COUNT         7592 a         6244 c         4904 g         9251 t
ORIGIN      
        1 aaatggtata cttaatctgt aaataacaaa aggaggacat aaatatgtct aaacattgga
       61 gacatctaat tattcactct gctctgacca ttctagctac gttattttta ggtatactac
      121 caattactga aaatactagt agtaccattt acgctgaatc gggcactatt tcaaataatt
      181 ggagtatcga gcaacacccc aattattacc atgttgaagg taaagcgcaa ctggatatta
      241 aaaattttcc cgaactttat cgtacaaccg aaagggtcta taagaaaagt gggcaaagta
      301 ctaaacctgt tacagtttcc aatatccatt actctgtact tgatggctac ggccgttctg
      361 gagaagctta tggtattatc acaaaagata tgattgacat gtctgctggc tatcgtgaaa
      421 aatgggaaag caaaccagag ccaagtgggt ggtattctta tttcttcaaa aatactaacc
      481 agagagccac tgaatccgac tacaagcata gccccaaaaa tgtgagtaag atttcgaaca
      541 atatcaaagc tagtattctc ttaagtaacg gaaatgttcg taacggctac ctgtttgata
      601 gaagtcattt aatagccgat agcttaggag gaagaccttt tagaaataat ttgattacgg
      661 gtacccgcac ccaaaacgta ggtaataatg atcgtaaagg tgggatgcag tatattgaaa
      721 ataaagtttt agatcacatt aaaagaaatc ctaaagtcca tgtttactat aaagcaactc
      781 ctgtatatca aggatccgaa ttgctaccta gagcagtttt agtgtctgct ttatcatctg
      841 atggatttat tgacgagaca gttcgtgtgt ttaataatgt agcaggtttt aatattgatt
      901 accaaaacgg tggactctta tcttctactg ctgacgtaga tattaataac gttgaagaaa
      961 atgaaatcga aactactgat gacgagattg aagagggaat cgaaaacgag cctgacacgg
     1021 atgcactaaa aaaagataac aaagatactt ctttacaaga cactgtatat gtggcaagta
     1081 atgggcaatc tgatgtatac tggtacaaca aagacagtat gcctaaaact gtaaacttag
     1141 agaaagttgt agaaatgagt gaacaagtag ctttgactag aggtaaacat cattcaactc
     1201 aagaaaatat agaataacaa attcaacaga ccaactagaa cttgaaatag tttttatatt
     1261 cttattagtt atgcataagc atacgaaaca cacaaaaaac cgccctcaat caagagagcg
     1321 gttttgtctt atctaattta atttacccca aaggctgata atgttaccat ctttgtcagt
     1381 tatcccaata gccatgtaat ttcgcatacc tgagccgcca agataactaa tccagtagta
     1441 gccattggca taaccctcgc tgtcaaagct gacagtgtct ccttgtttgt agctacctac
     1501 tacttcactg gctaggcttg gccaacgtct aatattaatc tccacaacat caagcgtaaa
     1561 ggtaccagat tttggtgtct ctacgattgt gtcagagttt tgtggtgctg tatctaccgt
     1621 ctgatgagca tggtcaacag gtaacctaat ccagccgaca acgccagtaa aatcacgagt
     1681 attaaaacgg gctggtccac ctacttgtaa gctatcccaa ttaccgtcaa tattttgctc
     1741 aacggtttta atagtatagc catcactatc ctcgatgaca gctcctgtat gtccgtaggg
     1801 actaccagct acctccatga caaaaaggtc actagctttg ggattgactc caggggcatt
     1861 atatatgacc tctagccctt gcgcagatgc gctatttaac aggtctatgg cattacccca
     1921 taaatcaatg ccgaaccagt ttttgacgat aaaacatggt aagtcacagc attgcgtccc
     1981 ataagcaccg tctttgtcaa ctcccatacc tgaattggca aggtcgacac agtattttac
     2041 aatctcattt gcggttgtca tcgttacctc cttttgattt gttaagattt ccttatccca
     2101 tttttgtagg tcattctcct cgattagttg gataagcagc tccgcatatc cacttgccgt
     2161 ggcataacct gcgtccttga tagcgtgaca ggctttttta tagtcagtct caccaacaac
     2221 agactgatag cgtggattat cgtttaaaaa cttgccatgg tcgataatgc tatcagtcca
     2281 gctatcatag gccctaaatc ggtccacaat atccgtgacg ataccaggct ggtactcctc
     2341 ctgcgtctta gtgttaaaag acttacctgt ccagcttgca tcagctttaa tcccaaacag
     2401 agcgttatgt ggggcatgtt taccccaccc gctctctaag attgcttgtg ctgcggtcaa
     2461 ggatggcaag attttgtact tagtccagcc atctaagcag ccttgcttaa tgttatctaa
     2521 aaaggtcatc tgtcctcctt atctacaaac gggtaaaaga taagagcaac cacagataat
     2581 ggcacataca gtattgcgat tgctagtatt aacgctaatc gtgtgattgc tcgcatggct
     2641 tattcctcgt ctttaatttg tgacacgttc atcaggacac atgttagtcc tgatagcagt
     2701 accgctgaca acattgttgg ccagttaata tccgtaatca acacgcttga cccgataaga
     2761 ccaaccgcag tttgtgccat tgttttgatt gttttaattc ctactttttt aaaccatttg
     2821 ctcatttttc ttcccctttt ttaaatagcg tgataatacg ctctttgttg ataataactt
     2881 cgtcttcgac gcgacctaaa cgctcttcgt gacgatcgat aatttttttg gtaatttcac
     2941 gatcgcgatc aagattttta agctcataag ctaactcttt gagagagtcc ttgagttgag
     3001 ccatggcaaa ctcattagct tccatggctt ttttaaaagg cgttacaact gccttccaaa
     3061 gaccaaaaac agacatgaga gccgctgccg cagctcctgc ctgtagtaaa tcaaagtgca
     3121 tctaaccacc tctaatcctg cttaaccaaa tcagcgtact tgataactgt gactttatcc
     3181 tctaattcct ctaaatcttt gagtgtttgt gcatcataag taaacttatc attgacataa
     3241 acaaagacta agttcccctc accggctaca ccgtccgtat ctttatcagc gtctacaact
     3301 gtaaaaatat catgctcttt gtactcacct tttttagcag gttcgatgag ctctaacatg
     3361 cctttataaa tgtcaggatc aatcttgcca ccgcttgtca aaacgtggat ggtttgcaag
     3421 ttaatcatct tttgcgtgcg ttcagcggac actttagcta gtccagcggc tgtttgagca
     3481 gtcttggcag tcttagcggt ttcttgtgag attttttcaa ggtcgtctac tttttgcacg
     3541 gcttcgccca ttgcaatttc gacgtaagca gtctttttaa actcctctaa agcagcctcg
     3601 ataatttctg catcattagc tgttctcaag tcttttttga ccttctctga gatgactgca
     3661 cctctgtcat ctgtaataat tacctgtgta tcaacgactg ctcctgtacc gtcccactgt
     3721 gggtagtttc ctgttacttt ccaatttctc atgtttattt accttcttcc ttcggtgctg
     3781 ttgcttcatc caattgtgcg tttaattctt ccaattcgat ttcatgctgt gcttttaatt
     3841 gagcattttc cagcgttaaa ttagcgactt taagtgttaa atcgttaata atttttccta
     3901 ataatttttc ttgcattgtt tctcctaaat tccagtcata taattgctat gctcgttcat
     3961 gatagcgcta gtaaaattcg ggtgtgtagt atcccagcca acattttgta gatgtttcca
     4021 gcaccttgcc aaagctacaa tcgcataata cattttattg atatccacaa gtgtgtttac
     4081 acccgttggt gtcattttaa atccacggtt tataccaaag tcatccgcaa aaatgatggt
     4141 atctccataa atttctgcct gatcaactga tgctgtatgt tcatatccgc tagccgtccg
     4201 aaaaaacctt gctccacaaa aacgaccaga tgacgcgcta ttgataccat caccagatga
     4261 agtgattccg attgacgcat aaagagccga ccttgtaaag ttttttggtg tcgcattacc
     4321 aaaatgcaca aaagcagtgt gggtacctga ttttcgaaca agcgcattat tgttgctgtt
     4381 gaaattgatg gatgcatcgc tattaaaatc gatggtagag ttgtttaaat caatcatcat
     4441 agcaccattt cttgctctga tgactttacc ctcaagcaaa cttgtaatcg tatgctcaat
     4501 ccttgcttta ataaagttag catctaaacc aacaatgctg ctagcgttga gattaatcac
     4561 attgattttg tttgcatcga ttgtcccacc gataatctgg tcggctttta gcttgataaa
     4621 ctcaccaagt tttgcgccaa acgctccatt aaccgtggta ttgccgtcta aggcgatacg
     4681 ctcgccagag atgcggacac cgtagccgtt taaattaatg gctgagacaa tctcacttgc
     4741 ggacattttg ctttgcggga gtttgccctt aatcgcaagc ataatactgt cgcctgcccc
     4801 acgaatataa ctctccattt caccacgagt gactttttgt tcaatcaagc cagctagttg
     4861 tgtgacacgg gattctaacc ctcggttagg ggcgctgaca gttgattgta accctctaac
     4921 tgtctgggtt aagctactgt aattcttctc agtatcctgc aatcgccgct gatagctagc
     4981 taggtcctgt tgcacacgac taacagcacc ctcacgattt ttaatctctt gtgagatttg
     5041 gtaggcagtt gattgttgcg ttgattgcaa cccactgatt cttgactcta gcactgtccg
     5101 catgccttga tggctacgag taaactcagc tcgtaagtcc gcaagcttac tctcgtaggc
     5161 ctctgtggtg ccgctagatg tcgtggttat cttagcagat aactgctgta tctcatcatc
     5221 atacttttgc gacaaacctt gagcggttgc ttgtatcaca gcttttaggt cgtttttatc
     5281 attggccatt gtggccttta ggccgttaat gccagcttga taagttgatg atagctgtct
     5341 atcagcgtct tgatagtcac gtctaatacc tgagactgtc tcattaataa gcgcaagttt
     5401 tttatcagta tcctcactaa tccgtgttgc tataccattt gcactttcga caatctctgt
     5461 tgtgatgtta tcacgatgat actcacgcaa catgccgttt gttgtgagtt tgatttttgc
     5521 ccaaagctga gaattaacgg tatctgtcag ctctaaatta agctctttta actgactgag
     5581 cgctccttcc aagtttttaa aaagtccggt tgacccaccg ctgccctcaa caaccactgg
     5641 cgccacgtag ttagttggct taccccctcg ctcaatcatg agctggttaa agcgagtcgt
     5701 accgatacat ttgttattag ctaatttaac gctttttgtg tcaccatcag ctttaaatgt
     5761 ataataagca cgtccgtcag agccaatcgt taaatttgac tcgtctatta aaagtgttgg
     5821 atctctactc aattgttacc tcctaatgtt gcgaaatttt aaatgttggg tttttatact
     5881 tgtctatccc atcaaacgga taagtccacg tctcgataga cagcattgcg cctccgccgg
     5941 caactgtccg aactggtttt tgtagcttag caacgatttt gccgtcaacc tcaacagcga
     6001 ctttatcaac tcgatgccaa acaaccccat aagtcgcaaa atcctgattg taatcaatga
     6061 cagcataatc atttaattta gatacgttag cgtctacata cgctgtaatg ttgtaaactt
     6121 cctgaggctc tgctgattga gaccaaatga cctgattatt acaaataacg cgagctattg
     6181 gcagtccatc aatagtaatc gattggtaca aacccatcgc ggcagaaggc ttttggacgc
     6241 tagtatctgg ttttgataat gactgatagt tatacttatt agctttatac acatcagcct
     6301 gtgtgctaga tataatttta tatacatcaa cgtcttgatc tgtgtaaaag ctatagtaat
     6361 catctatctt aatataaaat tggtcgacaa ccaaactggc tttttgtaat aaagtaccat
     6421 caatgctttg actgtctaag cggtaaaaat acgtgtctgg tatctcttgc actgccatta
     6481 cttacctcca gagcgttcaa aaacaattaa tccgcttgtg ttatatggca ctttaccttt
     6541 atcaaccaca cggacagata ggtactgacc tgttgccaca tcttttagct ttccgatgtt
     6601 gtttaactga tactggatat cagctaatct aacatagccg cttagctgcg catttcggac
     6661 aacgtcccta atatctgatt gcttaacaat gtcttgtggc agatcagttt gtttaaggta
     6721 ttcatctata ccatcaatat cagatgttct gtgccggtga tatgtacttg ctttgttttg
     6781 tagctctatt ttagtcgcat accggtctag gtttagatca gtaatatcac ttagcgagtg
     6841 cttgtgactt gctttagcat aagtgctgtt tgcctctgct ttagacagat agtctgcaag
     6901 ctgcttactc acatcaatct ctttaagttc tgcctttgta gcgtaggcag ataggtctac
     6961 gtccttagct ttaatttggg cgatttggtc agaagtaagg tcttcaaact ttaaggaatc
     7021 acccttatca cctttttgac ctttgatgtt gcctactaac ttttcagatt cttcttcaaa
     7081 cttgacaaaa aggttcccct cttcatcaac tcgagcactc tctactcctt ttcctctatc
     7141 ccctttttgg ccattaggga tactaaaggt tttttgagtg tcatctgata gtgtgatagt
     7201 aagcgtctca cccactttag tgatgtcggc aatacttgtc cctttatcac ctttttgacc
     7261 tttgatgttg ccaagcttag tctctttgtc gccaatccac acagacaagt caccattttc
     7321 ggatagctgt actttagtga tagattctcc ttgaggacct tcgtagtaag gcaagtcgtt
     7381 gtaattcaat ttgccatctc cgacctttag cctgtgagtg tctagctcaa caactagttc
     7441 accatcatca acaacaggat ttaatttttg ccattcggcg gcatccttgc ggtcaaataa
     7501 gactttaatt ggtattcttt cttctagcgt catctgtccc tccttccgtc taaaataatt
     7561 tttggattgc ttgattgttt agctgtgatt gttgcacctt tagcatcaac cacagcttta
     7621 taagccatat ccagagctaa aatttgcccc tctgacgcgg ttaaatctat ttgcttagat
     7681 ttataccaat cacctgttaa aacaccttta tagctcaaag gatagacctc tatagactgt
     7741 ttatccttag tgacctcaaa cgtctgtggc tccatcttag cctttgtcgg tgtcagcacc
     7801 agcttgagac ctttattatt agcctgtatc agcgtaattg ccactttatt tagtggctca
     7861 catgtctggc taaagctaat cgtataggtc tcgccacgct tgaaaccacc atcattggct
     7921 tctacctcaa taaaatcctc atcaattttt ttaacacgat tagggttgcc gaccagcaaa
     7981 tttttgttgt agcgggtctt accgtctgtg cctatgattt cggcgtttag acgggatgtc
     8041 tcgctcgttt cactgacttt gtttttgagg tcgtcaaagc tttgtttaat cgatgggatg
     8101 tcatcaacct tgatagcatc tgtgattttt ttaatggctt cttctggtaa cgctaggttt
     8161 ttgagtgttt ctctaaactc ttcaagctct ttgtcagtgc gccggttgat ttcttcttgc
     8221 gcttttttgg ctttttcgat tgcctcagag atttgttttt cgaggtcttc acgccatcgt
     8281 tctgggtcgt tcacaacctc gggttcctcc cactcagcac cattccaaaa gtacattcta
     8341 gtagtatcac caacttttag aaataatatg tctccttttt ttaaggttcc ttttggttca
     8401 tctttgggca tttctgtgcc accgtaaaca gtatttttcc catcagcaga tactagtgct
     8461 tgtgttgcta cttcaattgc agaagcaata tctgcatcta tctgattgat tctactgttt
     8521 atagacagac ttcctacgct ttgttttttc acagatccga tatcattaca agtgacttca
     8581 tgttttacta aagctccagt tgcgtcgtag tagcttgtaa aagaaactat ccgtatacgc
     8641 tcttgaaaac ctaaagtctc atttatcgcc ataatgtagt caccagcaac cggcctctca
     8701 catctataac cagctctcat taaatcttcc atatcaattt ttactgatat cttataagaa
     8761 ttttcaacat tactttttaa agcttctttt agattatctg ccaccgtgaa gcgctcatcc
     8821 gtcagaggcg ccccttcaag tcgaccgtac tccttggcaa gagggctttc gtattccgcc
     8881 tcaagtctcc ccttagagtg gtcctctggg tcggtccatg caccaaagcc tttctgatag
     8941 gtaataaagc tatcaatatt tttttcaatg gtaagatcat tcatgttgaa attttttcgt
     9001 accactgttg acagatcagt acctatgttt tttaatagcc gaacaacttt cccgctgact
     9061 gaaaactcaa gtccggtcgc tttaataatc tcattgaata aatctaacct agacttataa
     9121 ttaaaagatt gttttctaaa tgcgttcaca cctacttcta gcttatagcg gtacccacta
     9181 cctttaaata ctgtctctag ataggtatca atggtatgag acccatctcc gagaccctca
     9241 tagatactac tcttgctgaa gtcccaaaaa aattggtgta tggcatcaaa cgaaacttgc
     9301 gttttttgac caacatcaac aggctttgcg taaataacaa cgtaatactc atcttcaaat
     9361 ctaagtcgcc accctctatc gatattattg aggacatcac tgtttgtata aatttccccg
     9421 ctcactgagc gctcaccatt aacagcatta gtatgcctaa tgacactaat ggccccatac
     9481 tcaatgtcac gatgatccaa aaaagtaatc attagaccct cctatttata caactctaca
     9541 aaatttaaaa tcctaatcgt gccaagaaaa tccgttttgt aagtaattct cttgttagga
     9601 ttaggattga agataaaata ctcatagttc gttttagcat tgacataatt tccgtttagt
     9661 gtggtagcta tgcctgtcaa aagtaattta tcactatttt gtagctggct attctgctta
     9721 aactcaaagc gcctgccatc aatttcaata taaaaattag tctgacctcc agagggagta
     9781 agctctataa taaaaggcca ctctaactga cttgctttag cggttcctcc ataggcaaaa
     9841 ctgccccctg atagagttat gtcctttggt tttgtctcac cgaaaggtaa ttcagcagtt
     9901 cttagtgtga aggaaagatt atattttagt ccttgactgg tttttcctat aaattcataa
     9961 gcgatagtgt cgtctaggat gactttaaat ctatatttcc aaggtttatg aggagagcca
    10021 ataagttgca ggtctcctgt gctttcccct ggaagctcaa agttaaatag atctgagttt
    10081 tcagggtaca tcttagtcac gtagaaaggt tcgtcaacaa caagcagagc gtttagttcg
    10141 tcctgtttgt ccaaaactcc ttctacatcg cttaccgtca ctcttccttt gaccttaagc
    10201 gttttagtcg taaaagtagc cccatcgtag atgtaaccac tccttccttt gactgctcgg
    10261 tgtgatacag atagtagagg agcactatct tcaatagcaa tattataaat accaaagtca
    10321 gacaatctag ttgcctgact ctctttttct attaataaat ccaaaatact cccttctagg
    10381 caaaaacaaa ataagaatct ttagattgct ctcttgattc tttttcttta acagccgtgt
    10441 aaattttatc tccaacaatc tcattatgca cttcaaagat aggctctgac aattgagact
    10501 gcctaacctc ttcgctaaga ttatcaagag aggtattgat tccactatta ttaactttag
    10561 cagatgttga aacagtacta tttacccccc agttttgatc agtaactgct gttgcgtatg
    10621 ctttacctag actattgatc tcacctatcc actctgccat accgagggca aacccctctc
    10681 cagtaaatgc tcctagtgtt ttagtgacac gagatggcga gtgaatatcc agagcgcgtc
    10741 taattgttgc tgctacgtta gcggcaatgc tgttagctat tgcgtagatt gtgcctgcgc
    10801 tactagctag accattagca aaaccttgac ctgcataagc tcctgcagaa gacatctgcc
    10861 ctgccaaagc cctgaatatt gagaggatct tctgacaagc attattagac accgcggttg
    10921 cacgagacat cccagaagtc actgaactta caaggtttgc catagattgc tttgcagtac
    10981 tgttaatgct actaaatcct gttttaaccg cattggctat cccattcatt gaggttgttg
    11041 ctgaagtctt cgccttattg aagccagact caaccgccga ggacaaccta ttggcgcttg
    11101 aggttgcaga ggttgctgca gaagacattt cacttgtcac gctattagac agaccagagg
    11161 ctgctttagt tgagtttgac tgcattgatg ccagactgtt actcactcct gagctcatag
    11221 cttgcgcctg agaagttgca cttgtgctag cggttcccat gtttgcacca acaccactag
    11281 ctaagctgag cgtatgatta atggcgtcta gattcattga agaagtcgca ccattaaccc
    11341 ctgaagccat ttcttgagcc tgagtagtag cgttaatatt agccacagac atattagcgc
    11401 taatgccact cgcaagagac attgaatcat tcaacccctg aagactcatc gttcctgtct
    11461 gagcattaac attattagcc atctgtgtag catttgatgt agcgtttata ttagcaagct
    11521 ctgtattttg actaatgcta ttaagcatag atgtcgtatc tgtattggct tgattagcca
    11581 tagctgttgt ttgagtacca acattcaagg ccatggccgt ggcgtccgca gagactttag
    11641 ctgtacttgt ggaactctta cctgtgattt gatcccacat cgaactgaat ccgctcttaa
    11701 taccttccca aactcctgaa agagcatttg ggatagcctc taacatggct ttaccgagtc
    11761 ccgtaattaa ttgaataccc gcagaaataa tctgtggaag tccctttatc aaggctacgg
    11821 ctagttgtac aacaagctga atgcccgctg cgataatctg aggcagagct tgcgtcagtc
    11881 cagaaactaa agactgtata atctgtacag cagattgtac aatctggggt agattttgaa
    11941 taatcccctg cacaaggcta ataatgattt gaatgccacc ttgaagtaac tgcggtaaaa
    12001 actgtacaat tccagataca aaactcgtaa taacttgagt agctatctgc agaacagttg
    12061 gcaacatttg agtaattccc tgtacaagat tcaccaaaat agctataccg tggctgataa
    12121 tactaggaag gttagcctgt aaactgttcc caaaactacc aatgatttgc tgtgcttgct
    12181 ggataataag aggtatattt tgaactatgc cgttgacaac atttaataat agctccattc
    12241 caacagaaat aagctgcggc aaggcactcg caattgagct aacaaaacta ccaatgattt
    12301 ttattgctga actaattaaa ctcgttgcat tttgtccaat accttggacg agactggtaa
    12361 ttagctgaac gccagcttga attataaccg gtaataacac tgtgatagca tttgcaaatt
    12421 tagcaatcaa ttgagtacca ctagctatca aagctggtat tttagaagta atccctttta
    12481 caaggccttg aataatgcta gggccttttg ttacagcagt gttaagtagc tggtcgattt
    12541 gtgcgccaaa ctggctatta atcaaaccaa gtcctgccac cacaagtcct aggatagcgg
    12601 ccggtcctat ggccgccagt gctaaactca caagactgga cattgcgctt gtcatagttc
    12661 caagcacaga tagcccacgc cctgctgcgg tagcaaaaac gccaggtaat ccgcttagag
    12721 ttgccgcaaa ggcaccaaca acgccgctgg cactagctat cccactagaa attatgccgc
    12781 caaacacccc gacagaagcc cctaagcttc ctaaagctag accaactttt ccaaatagag
    12841 aaagcaaagg cattatcgtt gctatagcgc tagcggggtt catcactgcc caaagggcaa
    12901 tgaccttagg ggctaaagaa gtgatttttg cttttagatt atcaaaagcc tgccctgata
    12961 attcaccagt atgtgcaaaa tctccaagaa cagtattaat aagagcaaac acctctttaa
    13021 cgctggcgcc taatgggcta aagtcaatat tgatagactg ttttagccta gcgaatgctg
    13081 caactgcatt tggaataaga gaattaatcg tatcaaaaac gctggttatt gcgggcttca
    13141 ggctaagaag tgtttcagca atggtcttca taccattagc tttagccgct tcatcaaagg
    13201 ctgaaatcat acctgctacg ccttttacaa cggcggtatg tacgttcttc cacgcagttc
    13261 ggattccacc agccgatgat tgggccatct ctgcaaatcc gccttgggca tcgttaagct
    13321 caatcatttt atctgcgaac tcttgtgcag tgattttgcc atcagataag gctgatttta
    13381 aatcttgtac gccattttta ccaaaaccga aggcttccgc cattttagac attaaacctg
    13441 gcgcagcttc tgatacagag ttaaactctt cagcttgaat ttttccagac cccaacgact
    13501 ggttaaactg cctgagtgct tgctcagccc cttcagttgt tgccccgtaa ccgatcattg
    13561 cgttattgaa ggcgagggct aaactagtcc ctttatctaa acttcctgtg gttatggcga
    13621 gctgttgagc gctttttaca gcactgtcta gaggagttgg cagaccttca attccttttg
    13681 atagcttatc aattgatgcc ttagattgtt cagcagaata cccaaatagc gccatcgttt
    13741 tcggaaagcg gttcatggta tcaacgcgac taaccgcccc gtctattgcc ccagtaatag
    13801 cgtgcatagc tttttgaaca acagccatta aactaaaggc ctgcacgatg ctcatcactg
    13861 tacttttgag tctctctcca gcagaagagg tgttggcgaa tttctggctg attccattca
    13921 aggaagtagc cgcagaacta gacattctgc taaaaccatt gctaagacta ctccctattt
    13981 tacttgataa attagctaaa cttgaggtca gccgaccaaa caaactagta ctcactttgt
    14041 ttgcgaaagc agacgcctta gctgatacag aactaaaaaa attattccat gactgtaagg
    14101 ctgggttcaa gacttgccga ccaagtgaat tagaaatctt ccctccaaca gactgtatag
    14161 agctattcag ggtagaaacg gatgaggcaa tttttctaaa cgctgttccg aatggtcgcg
    14221 gaagcttgcc tgcgaccgtt tcgaatattg cagataagtt attaagctta ctacttgccc
    14281 tctgagttaa gatatcaact ccagtcgcag ccttggcaaa tgcagatctt atcttaccaa
    14341 tatccacaag attctgaagt tgcatttttg tttgattaat gaaaccggtt aagttacccc
    14401 gtattttgtc aataacactt gcaactggaa taatgatttt ttgaaaacca ttctttatgg
    14461 gttcgggaat tttttcgcca atggaagctg ctatgcgttg aatttcacca atactcagtt
    14521 ttaaaccagt agcgtaggcg gaaccaagtc tctttccgag cgattcgccg ttgttcgcta
    14581 attgggccat gatttgtcca atgatttgaa ccattttatt actactgtta accgctgtat
    14641 cttgggcttt tctgaaagca ttctgagtcg tactaacaat acgagccatg gcctgctcat
    14701 agtcctttgt gttggcacca atatcagcga aaatagaacc atcaaacgtt cctggcatct
    14761 actcctcctt atctatctat tttgaaaatg attattaagc atttgtattc tctcaacaat
    14821 actgctatca ctatcggctt ggctacggct agctttttga tacgatcttt tgatagttag
    14881 cctatgctta tcgtatttga gcttacctac atcaaccttt ttagcattta atgtatatct
    14941 aagttttaga gacaattcag agaggttctc gcgctcagca acctgcttat actcaagccc
    15001 ctccataata gcctctagct cccacttagt acatttatag atagtatcaa tgtctgtgag
    15061 ccctaaccgt gcgcaattta ctaagatact gcgttgctca ttcttccaat catgtcttcg
    15121 ataatttgga tttgagttgc gtccgtgtcg tccttcgctt tgagataacg agctgatttc
    15181 tccatgtttt cgatatattt caaaatcttc gctctgaaaa aaccagaatc aaccatttct
    15241 ttctctattt cagcaaacaa cccttctgtt gttccttctt catcaacagc ttctgcaatt
    15301 gcatctagaa tttcatcttc agttagcgct ttttttccgc ttcccgcaga taaacgcaca
    15361 aggtcaacaa tggcgctttc attacgctct aagatattga aaaacaaagc accaacacca
    15421 tctgcattgc gctctcctgt ttctgggtta attgttccta gtttattatt gatcttaaac
    15481 atagttttaa aatcaaattt aatatcgata tttcgtttcg ctgctgtaaa ttccattatt
    15541 ttatctcctt tttaaatcaa aatggggcag cagttgccgc ccctgtgtac tacttagtga
    15601 tattatcgta gtcgccagta gtatcacccg gattttgata gccgtatacg ttttctagca
    15661 tttcaatttc ttctttcgtg agagggaatt taccatcttg taaggcccct acaatgttag
    15721 cggtgtagga catttctact aagtctgaaa taccagtacc gcgttcgatt tcgtcaatct
    15781 tggcgtaccc aaacttagca gggtaaacat ctttcttggg tccagccgat tcagaaattt
    15841 ggatctgttc tttgacactt tcgtcggcaa tgacttccca aattttgata gatttacctg
    15901 ttttcttagc ttcctcgatg acagcaacag atggatctgt cggtacaaag tacgttgtca
    15961 aatcaataga gtgttcatct gtagccttct caataacgcg gccttgttgg gtttgctcat
    16021 caatgtattc accgcccatg gttgtagtac catcggtacg ataggctggc agcaaagcct
    16081 tgctaccttt tttagcatca actgattgga tgaaataaaa aatctttttc cctacaatcg
    16141 gtttacctgt tgtaatttca atagttgttc cttctttagt gtttgccatt taggtctcct
    16201 ttaaaatagt gtttctgtaa tgttgatagc aactctatag acttctcgtc ctattgaatt
    16261 atctaccaaa atctgagcct ttatttggtt attccgccca agtagtctaa gcaggcgagc
    16321 tttaatctct tctgcatcca aacgactatc gccaggtaag aaagcatcga tattcaggct
    16381 aaaatcgtca ataactgctc cagtttgagc tgtttttgac aagtctgata tatttgtacc
    16441 tacaacaata aaaggctcta aaacgtctga tttaggcaat ttaaaataga ttggtatgcc
    16501 taaagctccc aatctatttt ttaccttttt taaatatagt gtttctggtg agtaatccat
    16561 gcatcacctc ttaaacattt ttttgagatt agccattagc acaggccatt cttttctcag
    16621 ggcagggtct aaaaacggtt gagcttccat tttacgagta cctaattcaa gataaataga
    16681 atataaagca ggagaaacca ctctatagtg taagagtcgt tgttgctcat tgtagatttg
    16741 agctctcagc catccagtat caaccggggc tagtatttta gcctgtctct caatcctagc
    16801 agctgattta ctaagctctt tatctacagc gattcgtact gacttctgct tgcgctcaac
    16861 gctgcgtaaa aacctatcta ggcctctcat ccgataaata agactcatac ataaataacc
    16921 gtgctatttt tatggtgtgc tagtcccttt atcaacctcg gttttccctt gtagataatc
    16981 ttgctaaagc cgtcgtaatg gccttgcaag tgcaacttaa aagcattcaa atcatattta
    17041 ccaaatagcc ccatctgttc agattttgtg aaagtatttt ccatgcaggg gattttcccg
    17101 ctaggttttt caacagttct tttatctaga aaatcgtcct gctcatcgac atacactaag
    17161 attactctat ctttatagat cattgtgtat ctcctaaata aatcttgcta cccctttgcc
    17221 tgaatatacc ttcccaatag cagcgcttct gagtgttgat tcatactctt taaggtaact
    17281 gtcccactta aaagtctttc cttcttcgct atcttcaacg gttccttctg aattaatcct
    17341 attaaaccgt ttaatagcaa catcacggac aataaacctc aatctatcag gaattttggt
    17401 gatttcagtt tctgagtatt cattaagttt agctagcaca cgctctttac tttcagatat
    17461 agcaagggtg atgagctcat cttgcgcacc atcatccttg gaaataccta taaagagttt
    17521 gatatcgtca ataagttgtt tatcgcccat ataaatagcc tttaaccacc aatgccgggt
    17581 acagcagcag cttcgattgt tgcctctaca accccttcag gaatttcagc aaacagcaca
    17641 tttgccccaa agaaaacaga ttcataggta agattagaaa gctgacgatt acgagctgca
    17701 gcaattaaac ctgtctcatc agtaaaatca gcaaacaaac cacccaagtc tccgccttta
    17761 acatttaaag atgcaaaaac tagattctct acagccgttg agtagatttt accctctggc
    17821 acagatggca taacaatcac gttttgcata cccaaaaagt tcttaagcaa tgtcattcca
    17881 aaaacattag aagcatccgc acctacttta gtatctccaa gatagttggc tacgtctaaa
    17941 ggagagacaa aagaaacaag cggggaaccc tcaaactcat taaaagtagc tagcttagcc
    18001 catgatgcag acagcgcttt ttgaaggcca acgcctttaa cttttgttgg ttttgttttg
    18061 aggaatgtaa agaatgcatc cttaattcca ttctgaagct cacgcataat gcgcttatct
    18121 gcttcagtaa tagcacgagc tgcgccatgg cgagcaattg actcagctgt agttgcacga
    18181 cgtttcttga accacttcac tgtatagtct ttatctttag ttcgagtaac cttagacaga
    18241 gggatggttt ccccttctcc aggatcagtt tgatctaaag tcacttccca cttataggtc
    18301 tgaattttta gatcgttagt taatgtttca cgacgagtaa cccctagcaa ttttagtaaa
    18361 tcattaatat ttttggaaaa cttgttaaca aaatcaattg atttaatatc tcctaagtcc
    18421 gccatagtgt ttaaattttt ttcagccata atattcctct cttaaaataa gttacgattc
    18481 tcagcaatta aacgcatacg ttcgtcatca tcctctattg ccatgatgtc agccttagtc
    18541 ataccgaccg agccgtttcc agttcgtggt ggcttctggg ttaaacgatc gttaacacgt
    18601 ttttcgacag ctttatcaaa aatagtttgt aaattatcaa tattggcctt aacctcttct
    18661 gcagtagtgg ttaaaacaat atcaataaaa tccaatggca atcctttctc cacaagcagg
    18721 gaatgcgttt caatgcgcat ctcgcgctct gctactgctt tttcacgctc tgcgatagca
    18781 tctagacgtt tttgttcctc ctctttagcg cgctcatctt ttgacaactt ggccaaacgt
    18841 tcaccctctg tacgagcttt ttcaatagct tctgattgtt cagattccca tttagtgcgt
    18901 tcggcagcca tcatttttga gatgtctgcg cgagtaaaag ttcgctcatg ttcctgctta
    18961 ggatgttcaa cagcttcttt ttgagtgtcg acttgctcag ttgtttctgt tgttacattc
    19021 tcttctgcca taactttctc ctagtggtta cgccaccaac cgatagtcta gctttacgtc
    19081 ctgcgacgaa acagtgtagc ttttagtgtc atcaacaaag tttggacaca ataaaagccg
    19141 tattgctacg actttgattt ctaaaggggt cgaattcgtt taaaatttat tttccccact
    19201 tacgcttata atttttctta atgtagttaa catcaattgc aatgtttgta atagctgctt
    19261 gattatctaa agtagcagct ttaacagacg caaactcttc gtttgttgcc agagcgttcc
    19321 gctgaacaat tgatttcaac tccatgattt ctttgttttg atttttaatt gcttctgctt
    19381 gcatggcatt ctctgcaaca agcatcacaa ccactgtttc caatttacgt tttttcttaa
    19441 tgcgcttatt catgtttatc ctaccttttt caattctgca ataattgact taaccgctat
    19501 tgctgcaatg ccaacaatca atatgagcac caatacacct agtgccacta ataccatttg
    19561 ccaaataaac atattttcct ccttgatagt tttaataggg tgatgtataa ttgagataaa
    19621 gaaggatgat ggtctaacgc ccacgaagca gtttactgtg gaggcggtgg ggcatcatcc
    19681 ttctttttct aatacagcta atacctcatc tttatttttg ataattgata tatcaagacc
    19741 cctacgatct atcatataaa tttgttctaa ctgccccatt atctcttcaa atgataaagg
    19801 ggtttttgtt atatcaaaaa tgatattagt tgcctgcttt tttgcttttc gtagattgcc
    19861 atcaatgacg tttttacccg aacctgtgat ttcttttaga tcaaaaggaa ctctatcaac
    19921 taaataatca ggagtattga tatgttcagg ggaattaact cttggcacca tgtcaacttg
    19981 caatcctgtc tttttagata accaattagc aactctatat tcataattcg agtgatcaag
    20041 aacaacatta tggccatcta ctttgtaagg agtgccattt tttacatact catttagtag
    20101 tgacagttgt ggtttatgcc catttccatc tatccaatct gaggtgacat ccttaaaata
    20161 cttagtgctt ttatcatcaa ttggttctac ttcaatgctt agctcatctt catcaggaat
    20221 aagggttgtt ctgcagttga aatgataagg tgctgcatta attccaggct ttagctcaga
    20281 taatagcttt cttttgtttt ctttagcgat tttacgacat atctcagttg tcctgtcatc
    20341 acgcctaact aaatcacgat aatacttaag acctgcatcc aagtagcgcc tagcggtagc
    20401 attattaatc accatagttc catcagttct gattagtgtt tcagccctgt gattggcaac
    20461 attaaattgc ttagctaaat ctctggctat cgccctagga tgctcgccac gaacaaaacc
    20521 ttgttttaat ttcttttgga gattcttgac aagattgtca gtattgcccc acagctgttc
    20581 tgaatagtta taaccatcaa acggggttct aaccagttct tctaaaactg gaccattgat
    20641 tgtccctgac cgtccaccca ttgctttttt ataagcatat gaggcagctt tttttaaatg
    20701 attttcaaat gctgaatcaa gtacaccttt tagtatccct gcgcgataaa caagttcaag
    20761 atttaatgca tccatccttg tagctcttgc tgatacatac tgctcattaa gtcgttttag
    20821 cagctcaggg tctttctcag cttgtttgcg atacttgtta gcattagcta cgtaatctga
    20881 taaatcttca tgacgtagct ttttaacgac atcctgataa gtcattttgt tctcttcaga
    20941 atacttagta taaaaatcaa acaattcctt ttgtaactca aaagcctgtt cattatataa
    21001 cttctgcagt tctgaaaaga catctaaatc agctctgtct aaataactta gaatatcttc
    21061 ttgacgcttt tgccagtaat taaggctttt ctgctgttgg ttcttcttga ccactagcat
    21121 cacctaccaa tctaggctcc ggtaaagatt gctttttatc agcttcttct ttcaaacgtt
    21181 caagctctgc ttcagcgtct actcctgtga cagtgtttaa gatttcaaag atagtctgat
    21241 cgctaacaat gccataaaga ttttgtgcag ctgtaacaat ttcattatcg ttttgaggaa
    21301 gattaggtgt gaaaactata ctcgtatcat ttacaaggct atatgtagtt gcttcattcc
    21361 ctttgatggc ccagatatta gctgctaagc gtaagcgccg cattaagcct tttttgaaca
    21421 acctctcttg cttctcgcga tagttgtcag aagccataag cttatacttc attgattcac
    21481 cagattgaac tcctgaaaat ttcatatctt gtgtatctgg cgtaaaagta aacctcaaaa
    21541 tgtctgcaac tagtctattt ttgtaggctt cgctaccggc ggtatcatac tcttttttga
    21601 gaaagtacgc ttgtggttta acgccatttg gattaggatt atcgtctaaa attaacactt
    21661 gggctttttt aaacccaatt gagatcgcta aacgaccatt aggatttaat cgtccgtcat
    21721 ctaagtagtc attctcatca gcccctgtgt aagcattacc agctattaca agcaacgcat
    21781 tgactgaatc ttgttgaaaa ttagcaagct cggactgaga taaatcatag gcatcaatat
    21841 tatcaagtac agactcataa gcccctgtac gctcctcatt attagcatat tcattgactg
    21901 gtacaccttt aaaaaaatgt tcttcatgct cttttaagca cgtacctttt gtttcgagat
    21961 tatagtcttc gtaggtgtaa attgtgtcgg aagtatatac tttgataatc tgtttgcgtt
    22021 tacctgagcc ataatctatg ttgtaaaaat gaacggccat caacgaattt cgctggtatg
    22081 tatcatcata gataacaaaa gtttgctcgg ctgggagctg gtagagtttt acttcggttt
    22141 ttttgtcatc tatttcctca acagttaaca gctcgtaggc tcttccataa attgataaat
    22201 ctgtttttat tttgacgttg tggtagtcct cattgtttct gaccgacata aggtcaatag
    22261 ccgcctggag gtctttattt tcatttttgt actcaacggg aacaccaagc atataacctt
    22321 gctcaaatac cgtaatatat ttagcaaaat cacttgcaat acgattatcc gctgcgtatt
    22381 tatctgtttt agcaggtcta tacttgatgt tattatcccc aagatagtat cgctttaact
    22441 ctttcaaacg ctctaattgt tctgctttaa accttgaaat gtaattctta agttgatcta
    22501 tccaaagttt tgattcatag tcaattgctt caaagtcttc ttgcagcata ataaattgct
    22561 tattagcatt ctcattaaaa cgagttcctg ctaaaaattg tttttcttcc aaagtctcac
    22621 ctcattccta aaaataatat ttagcatttt tcatgcgctt acttctatcc gccgactggt
    22681 atattctgtc ttgtacggca tatcttatgg cgtcaatgca gtggttataa ctgtcaactg
    22741 gttcgttgat atactcatta gttttcttgt ctttcttcca agtgtaattt tcgagttctt
    22801 caatagtctt gacacacctt tcatcaacaa cccaatcata ctgaagcagg tactgaattc
    22861 cttgcataac ggttccaggc ccttttgtaa catcaatcat tctaggaata cctaaattcc
    22921 tcagctcttg gttagatttc ttttcagccg aatctcctct gatttcttct ttggcatagc
    22981 cgaggtcctt tatagcattt gctattttgt cattggtcaa attctttctg acatattcct
    23041 ctatgacgta taacttcttg tttgcgtcat cgattttaac atgcaaaaat gccgaagggt
    23101 cattgataaa cccatagtcc aaaccaaaaa aagaagacaa gtgtgataac ttgtctttgt
    23161 ttaatatttg cttgtcatat ttgggaaaaa ttagtttatc aagtgtagca aactggccaa
    23221 gagcatatat tttgtagtaa gcttcattcc tatcggctag ttcctcaata ttttctctcg
    23281 tgacatcatc taagaagcgg ttgtctttat aagttgtttg atagacaact gtattcttag
    23341 gtgtcttaac gaagaaggct ttataaaccc agtttacttt tgacacaggg ttaaacatca
    23401 agtatatttg cttctctaga tgtttcttat ctcttaaacg caaagtcaac tgcgtataat
    23461 catcaagcgt aaactcacta gcttcttcca tgacgacatc agatatcccc ttaattgact
    23521 taatcttctc agggttatcc atacccttaa aaatgaattc cgagccattc gggagcgtta
    23581 ttctaaaagc cgacatattt atcttacatt tatccaagat gccgaaatac gacaaattag
    23641 acatgatatc agcaaataca gagtctctaa cggttgcacc gacttttctg agaactaata
    23701 tctttctggg atgtttgaat ttagggttaa gtgcttttaa aattatcttt tgaaaaacac
    23761 cgtgagactt tccgctagac gccccaccat aatgaacttc cgtgaagttg ctatagttgt
    23821 aaagtttgtc gtagatatgt ttgttaaaaa ctttgctagg atacttgatt acgatattaa
    23881 ttttagggcg ctgtttaatc gtcatcccac tcacctacgt taatggttac atctgagctg
    23941 acatccattt caaccttgtc agtgaataat ctgtaccgct tacctagtag ctcagctgcc
    24001 ttgattctat cttttgcacc aacatcgatg tcaactatct tctggccaaa ctctccaacg
    24061 ctaatgagcg tcttttcttg ttggtctcct cgcataattg aagtgagata ttgtaggact
    24121 tcttcttgcg tagcaatctt ttcagattca agtttttcaa gccgctcgtc tatataagct
    24181 ttaatgtcag gtttggtcaa gttttcttga cctattgacc ttgctgtctt tttactatac
    24241 cctgctttaa tagcagctgc tgtcgcgtta gctgagatga tgtactcatc tgcaaaacgc
    24301 ttctgtttta gggttaattt actcaatttt ccatcacctc caagcataac aaaaaggcaa
    24361 gacactattt gccttacctt taaactcata ctatcaattt atcatcaaaa agatgacaat
    24421 tccatacatt tttgtgtcac attcctattt ttttggagaa tatttctaga atccgctctc
    24481 ttttgcggta aatagactta cgtgacagat gtcttgtata ggcaatttct tcccaagtgt
    24541 tacttgaacc aacaccccac ctaagattaa aaatatcagt tagctcttca tccaaaagat
    24601 ttagcgttgc aataactgct tctttgaaat tggatagacc ctttagttcc ctatctgaat
    24661 cccaccttgc aaccacatcc tcagtaactt ttgaaacaaa atttgctctt cctccaccga
    24721 tatttttatc tacttctgta ttcatatcag tttgtagctc aagttttcga agtgcaatct
    24781 tgttatcaat aaaacgataa tcaaacaacc attcatcaaa agcctttagc tgtgcattag
    24841 ataatctact catcccgtta cctctttatg aataattacg tgagaaatat tttgtttggg
    24901 tataataact gcgttgtttt ttccatttag agcaatgaca tcgttatttt tcattgcgcc
    24961 aattacttca tcaatacaaa tttcaccata attagaaacg ctcttagtag gaccttgctt
    25021 taaaaaaaat tcaattttca tttgctacct ccataagatt ttcaccgcaa aaaggacagt
    25081 gtttctgact atatgtttca tttttacact ctggacaaca tggtactgca taagttgtta
    25141 aatcacctac agcatctatc ccgttttcca ttctatggat tatattcata cctacccccc
    25201 catttcctgt caattctgca atccgtttgt ttgcgatatt aaagtaatct ttatttagct
    25261 catatccaat aaagtctctc cccgtcagta gacaagctac tcctgttgat ccgctgccca
    25321 taaaaggatc taggacaaca gccccttttg ttgtgtgtcg cgtaatgatg tccttcatca
    25381 gagctactgg cttttgtgtc ggatgctgtg ttttttctgc tcctgccaca actggatatc
    25441 tgtattctgg cctatcgtat ttttcagatt tacgattaaa tacccacttg gatttttttc
    25501 ggacgaccca taccccgtac tcgctatctg taatatacct tctatctctg tttctgggca
    25561 tagggttatc ttttacccac ctaaaaatat cctttactac taacccattt ttttcacaat
    25621 gtcttgcaat atctcctaaa tttttccaat cgttgaagat tatcatgcca ccgtttttag
    25681 ttaatttttg acttgcaatg tcaatccaac tcagtaaatc aaaaccttta tcccaatcac
    25741 caaaatctat acctgttcgc cccatggtag caaagttatt ttttactgat atgttgtatg
    25801 gtgggtccgt tatcaccatg tcgatcaatc catcagttaa ctccgctagt aattctaagc
    25861 aatttccgca ttttatttcc atgtgttttc ttacccccca ttccctgtca attccgcaat
    25921 ccgttttgtc tgtctagctc tatcctcact cgcacgttta agctgctttt gtgtcctgct
    25981 tagctgtgtc cgtaatcctg taatttgcgg ctcatagtgg ttttgtaagg ctatacttat
    26041 catcagtaac ataataactg ctgtcattaa gacggcaatt acattagact gcatatacaa
    26101 tctatcatct ttccgcttta tctcttctag cagcggtttt attagttctt ctgtcatttt
    26161 ttccactccc tagtatattt ttctttaact gttgcttcgc aagaattcca aaacttcaac
    26221 atgtccgctt ttcgcgtaaa ggttttctct tcaaactgag gttttgcctc aaaattcttt
    26281 tctctacccg tgtagattct aacgacatat tcttttttca tctagactcc taactgcgcc
    26341 ttaactgctt cgagtaaggc gttctgattt ttttctttgc cttgtaaaat cctaagtact
    26401 ttttcatcaa ctgtattttc tgcaacaatg tggtgcacaa taacgggttc tgtctgccct
    26461 tgtctatcta atctggcatt agcttgctga taatattcaa gactccacgt tagcccaaac
    26521 caaacaataa tatgcccgcc tttttgtaga ttaagcccat gcccagctga ttgagggtga
    26581 cacagaagaa ttggtatttt cccggaattc cacttgtcaa ctgacgtcaa ctcttcagcc
    26641 tgagggaatc gtttcttaag tctttcaaaa tcatgttgat actgataaaa aactaagatt
    26701 ggctggcctt ggctttcttc tactatgtcc tcaagcgcgt caagtttgtc atcgtgtata
    26761 gcaactgttg atttatcatc atcatagata gcaccattag ccatttgaag taatttattg
    26821 gccaagaccg cagagttagc cgcagatatt tccttatcct taaactccaa caccaaatca
    26881 gcttcaagct gtttgtaagc tttcatatta gataacttaa ctgatacaac gttgttggtt
    26941 cgcggcggta acttgagata gtctttagct ttcatgctga cacagatgtc ctcaatcttg
    27001 ttatagattt ctgcttctgc gccatcccta agcgcccaac tgtaaatgat tggaccatta
    27061 cgcttatcag gaacaaaata cttgtcttta aatcgagtct ggctagtctc aagcctgtcg
    27121 cctctgtcca tcagataaat ctgcggccac aaatcaatca aactgttagg cgctggggtt
    27181 cctgttagtc ctacaaggcg ttggactttc ggtctaactt ttcgcaaagc cctaaaccgt
    27241 tttgacttac tagacttaaa gcttgacagc tcatcaataa ccacaaaggt aaacggccat
    27301 ttagtcttgt agtattcaac aagccaggta acattctcac gattaatcaa atagatatca
    27361 gcttctgttt ctaacgcctc aattcgtttt ccctcgctcc ccaaaacttt agagtaggtg
    27421 aaatcaaaat gccatttctc aatctccgta ggccacgttt cttccgccac ttttttaggg
    27481 gctacgatta aaatcttatg atcctcggaa aaaatatttt gaatctcatc tatcgccgat
    27541 agtgttgtca gcgttttacc aaggcccatg tcaagtaaaa ggccgcaata agggtgctct
    27601 actatccatg tcttagcgta ttcctgatac tcgtgcagtc tcacacccag ttctccattt
    27661 cttttaaggc catgtccact gattcgtagg agtcaacaac ccaaacatgc tgcccagcct
    27721 cttttatttt tttgtgcatt gcaacttggc tgggtcttgg ttttttacca ggcgctttga
    27781 cctctacaaa aaaggttccc gtattcatga caacaattct gtcaggcact cctatcgtcc
    27841 ctggactagt aaattttaaa cacagccctt ttgttttctt tttcaaataa ttttcaatat
    27901 ctttttcagt cctcatcctt cctcctttgg tcaataaagg tcagggttac cgtttttttc
    27961 aacttacttt ctctttttta tatatgtgtt t
//
LOCUS       DAUGJR010000024        26195 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUGJR010000024 DAUGJR010000000
VERSION     DAUGJR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26195
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.024"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            62..280
                     /locus_tag="VH800_001059"
     CDS             62..280
                     /locus_tag="VH800_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8362135.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFYKLYNVSIDYLLGQTDYPYRFHNK"
     gene            complement(351..494)
                     /locus_tag="VH800_001060"
     CDS             complement(351..494)
                     /locus_tag="VH800_001060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362136.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            581..768
                     /locus_tag="VH800_001061"
                     /pseudo
     CDS             581..768
                     /locus_tag="VH800_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775620.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            924..1145
                     /locus_tag="VH800_001062"
     CDS             924..1145
                     /locus_tag="VH800_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEQ8362137.1"
                     /translation="MKEAYDELVRIRYGFSNNLSIENDNISFENYMNTIYLRAYKQKV
                     QAVTYEIALPHHKLFIQYFDSKLLKGITA"
     gene            1470..1853
                     /locus_tag="VH800_001063"
     CDS             1470..1853
                     /locus_tag="VH800_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ8362138.1"
                     /translation="MKVHTTLEKDENGNWYRKDQTKTPAGERLIELDDVTIVVLENWR
                     RNQVVNTDTDFIISRFGEPFCKSTICRVIKHKAQSIGVPVITGKGLRHSYASYLINVL
                     KKDILYVAKCMGHADKSTTLNTYSH"
     gene            2116..3351
                     /locus_tag="VH800_001064"
     CDS             2116..3351
                     /locus_tag="VH800_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8362139.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDHRYPGSALEEENMLSAQDVAIVTMHLLEDFPEILEITKQTEVDFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRLITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQVKELPISVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(3468..4430)
                     /locus_tag="VH800_001065"
     CDS             complement(3468..4430)
                     /locus_tag="VH800_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8362140.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSRFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEMGSAANLTLKQMKEMKQVGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            4762..6039
                     /locus_tag="VH800_001066"
     CDS             4762..6039
                     /locus_tag="VH800_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8362141.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYANIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLQDRYP
                     RLTPDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRQYWEKHIEKSVLLTH"
     gene            6068..6652
                     /gene="folE"
                     /locus_tag="VH800_001067"
     CDS             6068..6652
                     /gene="folE"
                     /locus_tag="VH800_001067"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEQ8362142.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            6661..7461
                     /gene="folP"
                     /locus_tag="VH800_001068"
     CDS             6661..7461
                     /gene="folP"
                     /locus_tag="VH800_001068"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEQ8362143.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            7468..7827
                     /gene="folB"
                     /locus_tag="VH800_001069"
     CDS             7468..7827
                     /gene="folB"
                     /locus_tag="VH800_001069"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEQ8362144.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            7824..8324
                     /gene="folK"
                     /locus_tag="VH800_001070"
     CDS             7824..8324
                     /gene="folK"
                     /locus_tag="VH800_001070"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEQ8362145.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            8474..9361
                     /gene="murB"
                     /locus_tag="VH800_001071"
     CDS             8474..9361
                     /gene="murB"
                     /locus_tag="VH800_001071"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEQ8362146.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTPSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHTGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            9407..10561
                     /locus_tag="VH800_001072"
     CDS             9407..10561
                     /locus_tag="VH800_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362147.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGFENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            10545..11339
                     /locus_tag="VH800_001073"
     CDS             10545..11339
                     /locus_tag="VH800_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362148.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            11336..12112
                     /locus_tag="VH800_001074"
     CDS             11336..12112
                     /locus_tag="VH800_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362149.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGIFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            12105..13178
                     /locus_tag="VH800_001075"
     CDS             12105..13178
                     /locus_tag="VH800_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8362150.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(13233..13898)
                     /locus_tag="VH800_001076"
     CDS             complement(13233..13898)
                     /locus_tag="VH800_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8362151.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRTQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKVFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(13879..15420)
                     /locus_tag="VH800_001077"
     CDS             complement(13879..15420)
                     /locus_tag="VH800_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8362152.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNYLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            15581..16912
                     /locus_tag="VH800_001078"
     CDS             15581..16912
                     /locus_tag="VH800_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEQ8362153.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTDFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMSPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            16943..18109
                     /locus_tag="VH800_001079"
     CDS             16943..18109
                     /locus_tag="VH800_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEQ8362154.1"
                     /translation="MKNQLGQLALEQAKTFGGKLEVQPKVDIKTKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(18192..19241)
                     /locus_tag="VH800_001080"
     CDS             complement(18192..19241)
                     /locus_tag="VH800_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEQ8362155.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCQDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVKPGDNVCIVGAGPVGLAALLTVQFFSPANIIMVDLSQNRLEAAKTFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            19477..20208
                     /gene="aphA"
                     /locus_tag="VH800_001081"
     CDS             19477..20208
                     /gene="aphA"
                     /locus_tag="VH800_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEQ8362156.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            20386..21918
                     /locus_tag="VH800_001082"
     CDS             20386..21918
                     /locus_tag="VH800_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEQ8362157.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVVVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPDYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            22081..22695
                     /locus_tag="VH800_001083"
     CDS             22081..22695
                     /locus_tag="VH800_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEQ8362158.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     VEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIKSYI"
     gene            22854..24002
                     /locus_tag="VH800_001084"
     CDS             22854..24002
                     /locus_tag="VH800_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8362159.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            24051..24731
                     /gene="radC"
                     /locus_tag="VH800_001085"
     CDS             24051..24731
                     /gene="radC"
                     /locus_tag="VH800_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEQ8362160.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(24733..25428)
                     /locus_tag="VH800_001086"
     CDS             complement(24733..25428)
                     /locus_tag="VH800_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEQ8362161.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(25438..26082)
                     /locus_tag="VH800_001087"
     CDS             complement(25438..26082)
                     /locus_tag="VH800_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEQ8362162.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT         7979 a         4389 c         5435 g         8392 t
ORIGIN      
        1 ataggacaat taaacatttt ttaatcaaat ctcctttata ctgatattag gagaatgtta
       61 gatgtatccg cgtattagga atttgagaga agataacgat ttcactcaaa agtttgttgc
      121 aaatttactt tccttctctc atgcaaatta tgcaaaaatt gagagaggag aggttgcctt
      181 aatggcagat gttcttgtgc agttttataa actctataac gtcagtattg attatttatt
      241 agggcaaaca gattatccgt atcgttttca taataaataa aagtctcgcc ttgatttgtt
      301 cattgacaac tgaataaacc gaggtgggac tttcttgttt gtcgagcaat ttagtgagat
      361 acgccgtgat aggagcgata attattagct ataaaataga gtggttctct atctgccatg
      421 accacaaata gggacaatga tacttctgaa cgttcaggct gccagcgtaa aaggccagtg
      481 ggtgagattc ccatgagtga tttaaccagt catacccacg gaggttgtaa tttttttgaa
      541 aggagtggag gtgtgaaaat agtaacatat aaaaagcttg atgaatattg gttttctcga
      601 acatactgca agaaatatta ttagagaagc aaaaagaata gctataaaaa agttgaagaa
      661 gctcgcgaac ttgaacaaaa tgcggtacaa ttaagtaaat cgccctttga caatagaaga
      721 cttggtattg ctcctaaaga tgaagaaagt ttagaaagtg agaattaaag atgactataa
      781 aaaatcaaaa aaagtacaaa ggtgtttatt gtgataagaa tgggaagata ttttatcaag
      841 ctgatcttgg tgtagatcca gtaacaggta aacgagttca aaagaaagcc agaaagaatt
      901 agtatggaaa gccatttggt acaatgaaag aagcgtatga tgaactggtt cggattaggt
      961 atgggtttag taataatctt agtattgaaa atgacaatat atcgtttgaa aactatatga
     1021 atactattta cctaagagca tataagcaaa aggttcaggc tgtaacttat gaaatagcct
     1081 taccacatca taagttattt attcagtatt ttgattctaa acttttaaag ggaataacag
     1141 cttgagattg tgaatctttt agtttacata ttattgaaaa ttatgcaaag aatttatggt
     1201 cgcgattcaa agcttgcatg gggtatgctg aaaggttaga ctatatttca aaagtgccat
     1261 gtaaggcttt ggataatcct aaagggaaac atcccgacac tccattttgg acttatattg
     1321 agtttcagaa ttttataaaa tcgtttgatt tgcaagatta tgaagagcta caaagattta
     1381 caactatttg gctatattat atgacaggtg ttcgtgtaag tgaaggttta tcattatgat
     1441 gggaaaatat cgatttcgaa caaaaattct tgaaagttca tacaaccttg gaaaaggatg
     1501 aaaatggaaa ttggtatcgt aaagaccaaa caaaaacgcc agcaggagaa cgtcttattg
     1561 agttagatga tgtgacaata gtagtattgg aaaattggag aagaaatcaa gtagtcaata
     1621 ctgacacaga tttcattatt tcacggtttg gtgaaccatt ttgtaaatca acgatttgtc
     1681 gagttattaa gcacaaagct caaagtattg gagttcccgt aataactgga aaaggattgc
     1741 gacatagtta tgcttcctat cttattaatg ttttgaaaaa agacattctg tacgttgcaa
     1801 agtgtatggg acatgctgat aagtctacaa ctttgaatac atatagtcac tgatttaatg
     1861 cattagataa aacagtatct gaagaaataa cccaaaatgt aataagttca ggattagatt
     1921 ccattttata ccaaaattcc tgccaaataa ctaattgata taacgaagct tattatatcg
     1981 cccatataac aggatgtgtt attgttacag ggtacttgct ttatgagctt gtttaagcta
     2041 ctaaaggtgt gtgccactat acttccttcc aaatttctga gaatttttgt tataatagta
     2101 actatgaaag atataatgat aaaaaggtgg gttatccttt tttttatggt attaacttgt
     2161 tcagggtttg gtaaaacagt tctcgcagct gattttcaag tgggagcaga acatgcgatt
     2221 gtcgtagagg cagactctgg gagagttctg tatgagaaag acgctaagac gccagatgct
     2281 attgcctctt tgaccaaatt ggtgacggct tatctggttt tagataaggt taaatcaggc
     2341 cagctgcaat tatcagatca agttaatctc tcagattatg ccttcgagtt aacaaaagat
     2401 aggtctttaa gtaatgtacc ttttgacaaa aaaacttatt cagttcaaga cctgttgaca
     2461 gctactttgg tagcaagctc aaatagcgct gctattgcgt tagccgaaaa agtggcgggc
     2521 tcagagcttc attttgtaaa tcaaatgaga gaacagctat ctcattgggg gattacttct
     2581 ggtaaaatcc tcaacgcttc aggactgccg aatgaggtgc taaaggacca tcgttatcct
     2641 ggttctgcgt tggaagaaga gaatatgttg agtgctcagg atgttgccat tgtgacgatg
     2701 catttactgg aagattttcc tgagatttta gagatcacta aacaaacaga agttgatttt
     2761 gctggtaatt ctattaaaag ttttaatcaa ctcttaccag gtatggctaa gggtagagca
     2821 ggagtggatg ggctaaagac aggaacgaca gatttggcag gtcattgcct tgtggtaact
     2881 tctattgaaa atggtatgag gctgattacc gttattctaa atgctgatgg atctgataaa
     2941 aaccaaaaca cgcggtttga gcaagcaaat cgcttgttgg actatgtggc tagaacttat
     3001 tgtcgtcgta agattcttaa aaaaggaagt cttgtctcgg agcgatcgct ccctattcaa
     3061 gatggccaag taaaagaact accgatatct gttgccgaag atgtaaccat cattttgcaa
     3121 cagggtgaac aagttcccaa acctaaacaa tttatgatat cagagacttc tttattagca
     3181 ccgattacta aaggtgaagt ggttgcttat ttgacgtctc caagaataac agatcagtca
     3241 gtgaggtatt taaaggaacc taagcgtatt cctcttaaag ctagccaatc tctaaaaaaa
     3301 gcctctgact tacagctgtg gtggcgagat tttcttgaaa aaagacgtta aagataagaa
     3361 taaaataatt ttaaaacaat caaaaaaaga cagttatgaa agaatttttt cataactgtc
     3421 tttttagttt acagtgagta tgatttggaa tgataaaaaa attgatgtta tggttccatt
     3481 gtttgtaaaa gattttcagg actcatgttt gggaggatac gaatccggtt aagagaaaga
     3541 agtccattag ccgcgctagc tattccttcg ttagtggtaa cacctaattt atagttaagt
     3601 ctagctgcaa tttgtaaggt agtgtcatta tatctaccag atggataagc aatggcaata
     3661 gtgttttggt ttaattgctt atcaagatag tcctttgaat ctttcatttc agttgtttga
     3721 acatcaggac tagcctgctc tagatcagga tgattcactg tatgatcttg gaaagacata
     3781 ccgacttgtt tcatttcttt catctgctta agagtcagat tggcagcgct tcccatttcg
     3841 gttagtcctg taataacatt attggtggct ttagcatcat atttttttaa gattgggtaa
     3901 gcaacattgt agaaatcaat catactgtca tcaaatgtta gccatacaac ttttttagca
     3961 ggcaattcat tatttgaaag agcgcggtag acctcttcag gactcaaaaa atagtagccc
     4021 tcgtctttca ttttttgaag ttgttgatca aagagatctg ggttgacaat caaattagca
     4081 ttagccgtct cttcagggga cattacatga atagcatgat acattaaaat tgggatcttg
     4141 acaggtgttt cttgcttggt ccaagtcaat ttagaatggg cctttttttg agattttgag
     4201 gaatcgaaat gagtcttctt aagttttgtc gtttcttttt ttgccgtctt tttgtgatga
     4261 aaaagactta ttttaggtac aaatcgagag acatctgaca agccgaattt gttagaccct
     4321 tgatataaat agaaaatgag ggtcaaacca agaatgcagg caaataatag tataaggtta
     4381 atgagagtga aggcttttct tttttggcgc cgtttatgtc tattgttcat tacttgctcc
     4441 tttttttgat ataagtacct ctattgtaac attttttaga gaaaagaagg cttgaagtca
     4501 gccttttttc ttgttttttg gaagaacgtg tattaaggag taaaaaaatt attgtcacag
     4561 ataacacttt aggaggtagc aaagactatg tggggctggt attcttatca cgtaaaaaaa
     4621 gcaatgaaga taaaagtgta gtgtacttta gaacttattt gagtgtttgg tgaggataat
     4681 aaaaaaaagg gtactactct aggttatctg ctgtcacttt tttttatata tggtatacta
     4741 aagatagatg tgaggtatga aatgacttat gaagagactc tagaatggat tcatgatcac
     4801 ttagttttcg gcatcaagcc aggcttaaaa cgtatgcttt gggttcttgg acagttagga
     4861 aatccccaaa aaaatgtcaa gggagtgcat atcgttggaa ctaacggaaa aggttccacg
     4921 gtcaatcatt tacaacacat ctttacgaca gctggttatg aagtggggac ctttacctct
     4981 ccttatatta tggatttcaa agaacgtatt agcataaatg gtcgaatgat ttcagaaaaa
     5041 gatttggtta ttgctgctaa tcgtattcgt cctttgacag agcgtctagt tcaagagact
     5101 gattttggag aggtaactga atttgaagtg attactttga tcatgttcct ctattttggt
     5161 gacatgcatc ctgtagatat tgctattatt gaagcaggcc ttggcggtct ttatgattcg
     5221 accaatgttt ttcaagcaat ggttgtggtc tgtccctcaa ttggtttaga tcaccaagct
     5281 attttgggcg agacttacgc taatattgcc gcccaaaaag ctggtgtttt agaagggggc
     5341 gagacccttg tttttgccgt tgaaaacccg tcagctcgag aggttttttt aacaaaagct
     5401 gagcaggttg gtgcttcaat ctgggaatgg caagagcagt ttcaaatggc tgagaacgca
     5461 tctggctatc gttttactag tcctttagga gttatttcag atattcacat cgctatgcca
     5521 ggacaccacc aagtgtctaa tgcagcttta gctattatga cttgcttaac cttgcaagac
     5581 cgctatccta ggctaactcc agatcatata agggaaggtc tagcaaatag tttgtggcta
     5641 ggccgtaccg aattattagc accaaatcta atgattgatg gggctcataa caatgaaagc
     5701 gttgctgctt tggtagccgt cttaaaaaat aactacaatg ataaaaagct tcatattttg
     5761 tttggtgcga tcgacaccaa gcctattgca gatatgttgg ttgctcttga gcaaataggt
     5821 gacttgcagg ttactagctt tcattaccct aacgcctatc cattggaaaa atacccagaa
     5881 cgttttggta gggttgctga tttcaaagat ttcttggcct tgcgtaagca tgctaaagca
     5941 gatgactttt tcgtgattac agggtcacta tattttattt cagaaattag acagtattgg
     6001 gaaaaacata ttgaaaaaag cgttctttta acccattaaa aaagagaaaa tgaaaaggaa
     6061 aaaactaatg aaaagggaaa gactaatgtc tattaataag gaaaaagcag aagcagccat
     6121 ttatcagttt ttagaggcta ttggtgaaaa tccaaatcgg gaaggtcttc ttgacacgcc
     6181 taaacgggtt gctaaaatgt atgcggagat gtttttggga ctgggaaaag atcctaaaga
     6241 ggagtttacg gctgtcttta aagaacaaca tgaggatgtg gtgattgtca aagacattag
     6301 tttttattct atatgtgaac accacttagt tcctttttat ggcaaggctc atatcgctta
     6361 cttgccaagt gatggtcgag taacaggttt gagtaaatta gcgcgagcag ttgaagtagc
     6421 tagtaaacga cctcaactcc aagagcgttt gacctctcaa atagcggatg ctttagttga
     6481 agccctcaat cctaaaggga ctttagttat ggtagaagca gagcacatgt gcatgaccat
     6541 gcgaggcatc aaaaagccag gtagtaaaac cattaccacc actgccagag gcttatataa
     6601 ggaaagtcgt gctgagaggc aagaagttat ttctctaatg acaaaagatt aggagaactt
     6661 atgaaaattg gaaagtttgt gattgagggc aatgcggcta tcatggggat tttaaatgtg
     6721 actccagatt ctttttcaga tggggggtct tacactactg tgcaaaaagc attagatcac
     6781 gttgagcaaa tgattgctga tggggctaaa atcatcgacg ttggtggaga atcaacacgt
     6841 ccaggttgcc aatttgtaag cgctaccgat gaaattgacc gggtggttcc tgtgatcaag
     6901 gccatcaaag aaaactatga tattctaatc agcattgata cctataaaac cgaaacagct
     6961 agagcagctt tagaggcggg tgccgatatt ctcaatgatg tttgggcagg tttgtacgac
     7021 ggtcaaatgt ttgccttagc agccgagtac gatgcgccta tcatcttgat gcataaccaa
     7081 gacgaagaag tttatcaaga ggtaacacaa gacgtttgtg attttctagg caatagagca
     7141 caagcagctc ttgatgctgg cgtgccaaaa aacaatattt gggttgatcc aggatttgga
     7201 tttgccaaat ctgttcaaca gaatacggag ttattaaaag gattggaccg cgtctgtcag
     7261 ttgggctatc ctgtcttgtt tggtatttcg agaaagcgtg tcgtagatgc cttgttaggc
     7321 ggcaacacca aagctaaaga gcgagacgga gcgacagcag ccttgtctgc ttatgccctt
     7381 ggaaaaggct gtcagattgt acgcgtacac gatgtcaagg ctaatcaaga cattgtggct
     7441 gtgttgagcc agttgatgtg aggacttatg gataaaatcg tattagaagg ttgccgtttt
     7501 tatggctacc atggagcctt taaagaagaa cagacccttg ggcaaatttt tctggttgat
     7561 ttagaattgt cagtcgattt gcaagcagct tctttgtcag accaattaac agatacggtc
     7621 cattacggga tggtgtttga tagtgtccgt cagttagtgg aaggggaaaa gtttattttg
     7681 attgaacgtt tagcaggtgc gatttgtgaa cagcttttta acgaatttcc gcctattgaa
     7741 gccatcaaag tggccattaa aaaggaaaac ccaccgattg caggccacta taaggcagtt
     7801 ggtattgaat tggagagaca gagatgacca ttgtttattt aagtttaggc accaatatgg
     7861 gggaccgagc agcttacttg caaaaagctc ttgaggcttt agctgactta cctcaaacac
     7921 ggttgcttgc tcaatcatcc atttatgaaa cgactgcttg gggcaagaca ggccaggctg
     7981 attttctcaa tatggcctgt caattagata cacaattaac cgcggctgat ttcttaaaag
     8041 aaacacaagc tattgagcaa tctcttggtc gtgtgaggca tgaaaaatgg ggatcaagaa
     8101 ctattgacat tgatatcttg ctatttggag aagaggttta tgacacaaag gaattgaaag
     8161 tgccacaccc ttatatgact gagcgtgctt ttgttttaat ccccttattg gaattgcagc
     8221 cagatttaaa attgcctcct aatcataagt ttttaaggga ttatcttgca gctttagatc
     8281 aatcagatat cacactcttt tcagctcaac agacagagtt ctagactctg ttttcggagt
     8341 aatgcctgct ataagccaat ccataaagtt ttgccaaatt catcgttatt ttttctaaaa
     8401 tttgatataa tagtatcggc tttatgccga tttttttacg tgtataagaa gtgataaaag
     8461 aaagaagata actatgataa ctgaacttca tgggattgat attcgagaga atgaacccct
     8521 aaaacattac acttacacta aggtaggtgg cccagcagat ttcttggctt ttcctagaaa
     8581 tcactacgag ctatcacgca tcgttgctta tgccaacaaa gaaaatatgc cttggcttgt
     8641 tttgggaaat gccagcaatc tcattgtgcg agatggtggt attcgtggct ttgtcatcat
     8701 gtttgataag ctaaatgcag tgcacttaaa tggttatacc ttagaagccg aagctggtgc
     8761 caatctgatt gaaacaacga agattgccaa attccatagt ttaacagggt ttgaatttgc
     8821 atgtggcatt cctggaagca ttgggggtgc tgtttttatg aatgcgggtg cttatggtgg
     8881 ggaaatatca catattttct tatccgctaa ggtgcttacc ccaagtggag agatcaaaac
     8941 catttcagct agggatatgg cttttggtta ccgtcactct gccattcaag aaacaggtga
     9001 cattgtcatt tctgctaagt ttgctcttaa accgggtaat tatgatacga tcagccaaga
     9061 aatgaatcgg ttaaatcacc ttcgccaact aaaacaacct ttagaatttc catcttgtgg
     9121 atctgtgttt aagcgcccgc caggacactt tgcaggtcaa ttaatcatgg aagcaaatct
     9181 taaagggcat cggattggtg gtgtggaagt ttccgaaaaa cacactggtt ttatgattaa
     9241 tgtggcagat ggcacagcta aagattatga agatttgatt gcttatgtca ttgagacagt
     9301 tgaaaaccat tctggtgtca ggcttgaacc agaagttcgg attattgggg aaaacctgta
     9361 accattattg ataattaaag aaagtaccgt ggaggattta tgacaattga ctaagccaat
     9421 tatcacattt aacaatgttt caaaaacatt tgaggacagt ggaacacagg ttctaaagaa
     9481 cattaacttt gaccttgaag aaggaaaatt ttacaccctg cttggagctt ctggctctgg
     9541 aaaatcaact attttaaata ttatggcggg cctactagat gccagcagcg gagacattta
     9601 tttagatggg gaacgtatta atgatttgcc gattaataaa cgtgacattc ataccgtttt
     9661 ccaaaattat gccctcttcc ctcatatgac tgtttttgag aatgttgcct ttgctttgaa
     9721 gctgaagaaa gtggacaaga aagagattgc taagcgcgtg aaagaaacct tgaaaatggt
     9781 tcaattagaa gggtttgaaa atcgttctat ccagaagttg tctggtggtc aacgtcaacg
     9841 tgttgccatt gcgcgtgcga ttatcaatca accgcgtgtg gtcttacttg acgaaccact
     9901 ctcagccctt gatttgaaat taagaacaga gatgcaatat gaattacgtg aattgcaaca
     9961 acgtctaggc attacctttg tttttgttac tcacgatcaa gaagaagcct tggccatgag
    10021 tgattggatt tttgtcatga atgaaggtga aattgttcag tcgggaacac cagtggatat
    10081 ttacgatgag ccaattaatc attttgttgc taattttatt ggagaatcta atattattaa
    10141 cggtaccatg attgaagact atcttgtctc ctttaacggg aaagaatttg aatctgtgga
    10201 cggtggaatg cgccctaatg agcctgttga agtggttatt cgtcctgaag atcttcaaat
    10261 tactttgcca gaagaaggga aattacaagt taaggttgat acccaattat tccgcggggt
    10321 tcactacgaa attattgcct atgatgaatt gggtaatgaa tggatgattc attctacccg
    10381 caaagctatc gaaggagaag ttatcggatt agattttacc cctgaagatc ttcatatcat
    10441 gcgtcttaat gagactgaag aggaatttga tgcccgtatt gaagaatatg tggaaatgga
    10501 tgagcctgaa gatggattga ttaatgccat tgaggaggag cgtaatgaag aaaacctcta
    10561 gtcttttttc gattccttac ttcttatgga ttctcttttt tgttgtggca ccagtcactc
    10621 tcttgtttta caagtccttt tttgacatag aagggcgcgt gaccttagcc aattatgaaa
    10681 ccttttttag ctcttggact tatttgagga tgagtgtgaa ttctatttta tacgctggta
    10741 ttatcacact cgtcacgctc ttgatttcat atcctacggc tctcttttta acgcgcctaa
    10801 agcacaagca gttgtggctt atgctcatta tcttgccaac ctgggtaaat ttattgctaa
    10861 aggcctatgc ctttatggga atctttggtc aacaaggagg gattaacagc tttttaacct
    10921 ttatggggat tggcccgcag caaatccttt tcacagattt ctccttcatt tttgtagcct
    10981 cttacattga gctccctttt atgatgttac cgatttttaa cgctttggat gatattgacc
    11041 ataatgtcat caatgccagt cgcgacctag gagctagtga atttcaggcc ttctcaaaag
    11101 ttatttttcc cctttcttta aatggggtta gggcaggtgt tcagtctgtc tttatcccaa
    11161 gtttgagtct ctttatgtta acccgtttga ttggtggaaa ccgggtgatt acacttggta
    11221 cagccattga acaacatttt ttgaccaccc aaaactgggg aatgggatca accattggtg
    11281 tcgtcttgat tttgaccatg gttgctatta tgtggctcac aaaggagaaa agtaaatgaa
    11341 aaaatttgcc aatctttatt tagcgagtgt ctttgtttta ctctacattc ctatttttta
    11401 tttgattttc tattctttca acaaaggtgg ggatatgaat ggttttacag gatttaccct
    11461 tgagcattac caaaccatgt ttgaggatag tcgtctcatg acaatcttac tgcaaacctt
    11521 tgttcttgct tttagtagcg ctctactagc aacgattatt gggatctttg gagctatctt
    11581 tatccaccat gttagaggta agtaccaaaa tgccatgcta tcagccaata atgtcttgat
    11641 ggtatcacca gatgtcatga ttggggcttc ctttttaatt ctttttacat cattgaagtt
    11701 tcagctgggc atgtcttcag ttttattaag tcatattgct ttttcgattc ctattgtggt
    11761 tttgatggta ttgccgcgct tgaaagagat gaatcaggac atggtcaacg ccgcttatga
    11821 tttgggagct aattatttcc aaatgctcaa agaagtcatg ctgccatact taacaccagg
    11881 gattattgca ggttatttta tggcctttac ctattcctta gatgattttg cagtgacttt
    11941 ctttttgact ggaaatggtt ttactacttt atctgttgag atttattcgc gggctcgtca
    12001 gggaatttcc ttggatatca atgctttgtc aaccatcgtt ttctttttct ccatcctctt
    12061 agtgatcggt tattattata tgtcacagga caaggaggaa aaacatgcgt aaactttatt
    12121 cctttctagc aggagttttg ggtgttattg ttattttaac aagtctttct ttcatcttgc
    12181 agaaaaaatc gggttctggt agtcaatcgg ataaattagt tatttataac tggggagatt
    12241 acattgatcc agctttgctc aaaaaattca ccaaagaaac gggcattgaa gtgcagtatg
    12301 aaactttcga ttccaatgaa gccatgtaca ctaaaatcaa gcagggcgga accacttacg
    12361 acattgctgt tcctagtgat tacaccattg ataaaatgat caaagaaaac ctactcaata
    12421 agcttgataa gtcaaaatta gttggcatgg ataatatcgg gaaagaattt ttagggaaaa
    12481 gctttgaccc acaaaacgac tattctttgc cttatttctg gggaaccgtt gggattgttt
    12541 ataatgatca attagttgat aaggcgccta tgcactggga agatctgtgg cgtccagaat
    12601 ataaaaatag tattatgctg attgatggag cgcgtgaaat gctaggggtt ggtttaacaa
    12661 cttttggtta tagtgtgaat tctaaaaatc tagagcagtt gcaggcagcc gagagaaaac
    12721 tgcagcagtt gacgccgaat gttaaagcca ttgtagcaga tgagatgaaa ggctacatga
    12781 ttcaaggtga cgctgctatt ggaattacct tttctggtga agccagtgag atgttagata
    12841 gtaacgaaca ccttcactac atcgtgcctt cagaagggtc taacctttgg tttgataatt
    12901 tggtactacc aaaaaccatg aaacacgaaa aagaagctta tgcttttttg aactttatca
    12961 atcgtcctga aaatgctgcg caaaatgctg catatattgg ttatgcgaca ccaaataaaa
    13021 aagccaaggc cttacttcca gatgagataa aaaatgatcc tgctttttat ccaacagatg
    13081 acattatcaa aaaattggaa gtttatgaca atttagggtc aagatggttg gggatttata
    13141 atgatttata cctccaattt aaaatgtatc gcaaataagc actcaaaaag gctggtattt
    13201 ctccagcctt tttaatgtat cgacagatga cgtcaccagt acacgcgata ggggcggcca
    13261 acctttgtaa aaatttgttg gctgttcagt tgcttatttt cttctaaata agcaatgtat
    13321 ttacggacag agacatggga taagtgacaa gcggaagcta attcttggat agtaaaaggt
    13381 tgatcaaaga ctttgatatt ttccataatc cactggaaag tggattcaga taagcctttt
    13441 tctaacaatt gtttgttttt agtgtctttt ttgctagtca aacatttcag ttggtcaatt
    13501 tgggcctgct ctagttgctg attggccaaa tgttctcgat gtgtaacaaa ctgttggatg
    13561 ctttcttgaa agcgttcaaa ggtaaagggc ttgatgaggt agtcgataat tcctaaatga
    13621 aaaccatctc ggataatatt cccatcattt gcggctgaaa taataatgac ttcgcaagga
    13681 atatgctgag tacgccattt ctccaaaaat tgaatcccat tgccatctgt aatatgaata
    13741 tccagtaaaa tgaggtcaat tgcgtaatca gtaagtatgc tttgaacagc tttcatagag
    13801 tcgctggata taatgcgatc aaaaagattt agtttttcga ggtaattgcg atggataaaa
    13861 tccaccatag gatcatcttc aatgattaaa acgttcatgt tgccctccta cataaggtgt
    13921 tgtcactgag aactgtaact cggttacggt ttgatgttga tggaattggg aatttgtatc
    13981 ggtcaagagc tgttgaaaat aaggtaagtc aaaaataggc tgtacccgct ccaaatcaat
    14041 ccaattgtct gtcaaggtgt aatggctgat taaatgattc tggtcatgtt gaatactcaa
    14101 aacgagtgat ttgggtctca gtgtggttag aagattagta tggataaagc ggtaaatcat
    14161 caaaccatta ttaagttgat tcttggtggc agaatgagga atctcgctta aaacatcaat
    14221 cttgagatgg acatttaatt cttggtattt ctcttgctct ccaatgagaa aactagctag
    14281 aagaggctcc ttaacaagga cagataagct agtgagaatt tcattttcgg gttccaaaat
    14341 actgtctaaa taaattttca attggtcata ataagcaata tccactaagc cataaataac
    14401 atgcaattga ttcatgaatt tatgagtttg ggcttgtaga gcagaagcat aggcagtggt
    14461 ataggctagc tgatccaagg tatcaatagc cttaactgct tctcgcatga aaataatatg
    14521 gcctcggtga tcgtttttga cacagatggg tgaaatggct aacaagtagt cttcctcacc
    14581 ataccgaaag agttgttcat gcccctcttg caaactaagt tttggaaaat caggaaagag
    14641 gtaattgaaa ctgttgccag taggttttcc caactggcat ttccgagcaa ttaatttttg
    14701 tccagcctga ttgcagagct gtaagatacc agctttatct accacaaata cggcggcttc
    14761 gatttgatcc aacatggcat tacgctcttc aaagagctga taaatttcac ttggttctaa
    14821 ctggtgcagt tgacgcttga gtcgaaaaga aataaaactg gtgaccagta aactaataag
    14881 aagacaaagg agtaaagaca gggtataatt gcgttttgac gttaaagcca catcatttag
    14941 ggtagttagt ttaatgccaa ccgcaatagc accaatctgt ttgtcaccgt caaacacagg
    15001 tactagatag cgaagtgact ttcctaaagt gcccttggcg gtagagataa ccttttttcc
    15061 tgctagaaca gcctcctcat cacctccttg aaaaggtttt ccgatatttt tcgggttagg
    15121 atgggtgagt cgaatccctt tcatgttcat cacgaccaca taatcaaggt tatagatgga
    15181 ggcaatggag ttggtatagg ctgttgtttt agcatttggt tggttgttta ggagtaattc
    15241 tttaatcgct tgatgacttg ctaacatttt tccagttgac gttagcaaat gggtttcctg
    15301 atttttgatg gattggtgcg tatcatgtag cataatcccg taaaatagag aggttgtgac
    15361 aacaatcata gataccaaaa tcaacgataa actggcccat aaacgtagtg gttttttcat
    15421 aaggtctcct ctttattgag tataacacga taagaaatga cctgctagct taaattaatt
    15481 aaataacttg aaaaaattaa agtagttaaa caacttaaat aaactatgct tttgacatgt
    15541 tctcttttat actagcctta tcactaaagg aggttgtttc atggaaacaa taagcaagaa
    15601 aatgcctcaa aaagacttgt ctgagcattc aaaagcatgg caaaataggc gaataggctc
    15661 cgttcccttg cctgtttatc tggttttagc taccttaatt ttagtcacag gctggctcca
    15721 acaattgcct gttaatatgc tgggtggctt tgctgttatt ttaacccttg gttggctact
    15781 aggaaccatt ggagcgacca ttccaggcct caaacatttt ggtggcccag ctattttatc
    15841 actcttagtc ccttcgattt tggttttttt taatctcctc aatcccaatg tcttagaagc
    15901 gacgaatgtc ttgatgaagc aagccaattt tctttatttt tatattgcct gcctggtctg
    15961 cggtagtatt ttaggcatga atcgaaaaat cttgattcaa ggtctttttc ggatgattat
    16021 tcccatgtta cttggaatgg tttgtgcaat gggtgtaggg actttggttg gcgtcatttt
    16081 aggattagac tggcaacata ccctctttta tgttgtgacg ccagtccttg ctggaggaat
    16141 tggtgaaggt attttaccct tatctcttgg ttacagtgcc attacaggag tcggaagtga
    16201 gcaattagtg gctcaactga ttccagccac cattattggg aatttctttg ctatcttgtg
    16261 cacggctttg ctcaatcgtt ttggagagaa gcacccaagt tattctggtc aagggcaact
    16321 ggttaaaatt ggtcacagcg aagacatgtc tgatgcccta aaagacaatt ctggagccct
    16381 agatgttaaa ttaatggggg caggcgtttt aacagcttgt tcacttttta ttgctggtgg
    16441 cttgttacag catttaacag attttccagg accggtgttg atgattattc tggcagcctt
    16501 cttgaaatac ctgaatgtta ttccccaaga aacccaaaat ggtgccaagc aactttataa
    16561 attcatttcc agcaacttta cttttccgtt aatggcaggg cttggtctac tttatatccc
    16621 cttaaaagag gttgtggcaa cccttagctg gcaatatttt attgtggtga ttagtgtggt
    16681 gttaacggtt gtcagtgtcg gtttttttgt ctctcgtttc cttaacatga gcccagtgga
    16741 agcagctatt atttcagctt gtcaaagtgg tatgggtgga accggtgatg tggctatttt
    16801 gagtacggct gaccgcatga atctaatgcc gtttgcccaa gtcgctaccc gtttaggtgg
    16861 ggctattacc gttatcacta tgacagctat tttaagaatt atttttagtt aatccgaacc
    16921 aataaaaaga gaggtatttc ctatgaaaaa tcaattaggt caacttgccc ttgaacaagc
    16981 caaaacgttc ggcggtaaat tggaagttca accaaaagtt gacattaaaa ctaaacatga
    17041 tttgagtatt gcctacacac caggtgtagc gagtgtgtca tctgccatcg caaaagataa
    17101 aacattagca tatgacttaa ccaccaagaa aaatacagta gccgttatca gtgatggtac
    17161 tgcggttctt ggtctggggg atattggccc tgaagcagcc atgccagtta tggaaggaaa
    17221 agcagccctt tttaaagcat ttgcgggtgt tgatgctatt ccgattgtat tagataccaa
    17281 agatactgaa gaaattatta gtattgtcaa ggcgcttgca ccaacctttg gtggtattaa
    17341 tttagaggat attagtgcgc cccgctgttt tgaaattgag cagcgcttga ttaaggaatg
    17401 tcatattcct gttttccatg acgatcagca tggaacagct attgtggtgt tagcagccat
    17461 cttcaatagt ttgaaacttc ttaaaaaatc ccttgatgag gtatccattg tggtgaatgg
    17521 tggtggatct gctggattat ccattacccg taaattatta gcagcaggtg ctacgaaagt
    17581 gacagtagtg gataaatttg gcattatcaa tgaacaagaa gccgctcaat tagcgccaca
    17641 tcatttggat atagcgaaag tcactaatcg tgagtttaaa tcaggtacct tagaagatgc
    17701 tcttgaagga gcagatatct tcattggcgt atcagcacca ggagtcttaa aagcagagtg
    17761 gattagtaaa atggcagcgc gcccagtaat ttttgccatg gccaacccta ttccagagat
    17821 ttaccctgat gaagcccttg aagcgggggc ttacattgta ggtactggcc gcagtgattt
    17881 tcctaaccag attaataatg tccttgcctt tccaggtatt tttaggggag cattagatgc
    17941 acgggcaaaa accattactg ttgagatgca aattgctgcc gcaaaaggta ttgccagtct
    18001 tgtcccagat gacgctttga gcactactaa tattattcca gatgccttta aagaaggagt
    18061 cgctgagatt gtcgctaaaa gcgtcaggtc ggtagtcctt aaatcataga atatatgaaa
    18121 aaaaagagaa agttatactt taaatcacaa aataagtaga agcatatttc tagcttctac
    18181 ttattttgtg attagctaat atcattatca ataataactt tcaaggcgtt atttgcacca
    18241 gcatgtttaa aggtttcata agctttttca acttctgaaa gtttaaaatg atgtgtaata
    18301 agtcttgttg cgtcaatctt tccagttttc aagacattta gtagcatttc agttgtattg
    18361 gcattaacaa gtccagtgtt taaggtgata tttttaatcc ataattcatc caggttgaaa
    18421 tcaactggtt tcccatgaac cccaacgtta gcaatatgcc cacctactga tataattttt
    18481 tgacaaatat caaatgtcgc gggataacca acacactcca tggaaatatc gacaccacgt
    18541 ccattggtta tatcgtcaat gatagccttg acttcttcac tacttcctga acaaatcgtg
    18601 tgtgtggctc caaatgtttt agctgcttca aggcgatttt gagataagtc gaccataata
    18661 atattggctg gagagaaaaa ttgaacggtt agtagggctg cgagtcctac tggaccggca
    18721 ccaacaatac aaacattatc tccaggcttg acatgtgatg gcaagacacc aatttcatat
    18781 gaagttggta aaatatcaga aagcatgaca agtgcctcat catcaatcgt atcaggagca
    18841 tgatagagac taccatctgc atgtgggata tggacatatt ctgcttgtgt tccattaatt
    18901 aaatggccaa gaatccaacc gccatcttga caatgtgacg aaaggcctcg tttacaataa
    18961 taacaggtat gacatgatgt gacgcaagaa ataatcactt tatctccgat tttaaagtta
    19021 gtaaccgcat caccgacctc cttaacaatt ccaattcctt catgaccaag gattgttcct
    19081 tctttacatg cgggaacatc cccacctaag atatgcaaat cagttccaca aatagtggtt
    19141 tttaccaact ggacgatagc atctgtaggc tttataatga ctggttttgg tttgtctatg
    19201 agctgtagat ttccggttga aaggtaagtt gctgctttca tatttaactt cttataaggt
    19261 tgagaggtaa tcaaccaatt catttttaca cagatattat aatattttaa gaaagggttt
    19321 tcaatatttt ttaaatcgat tatgataatt ttttagatca tctttgttga ataacttcat
    19381 ccttattcag aacttaaagg gtactattat aagaatttga aaccgcttta cttaaaccgt
    19441 gtatttttgt acaataatga ttaaggaggt ttttagatga aaaaagaatt taccagtatc
    19501 ctgtttacag ttagtttttg tggaatcata gcattgcctg tcgaagctag tggccctaaa
    19561 gttccttata cacaagaagg tataacggcc atttcaaatc aggcaacagt aaaattgatt
    19621 tctattgctg atatcgcgag cagtttagaa ggacaaaaac ctataacggt tagttttgat
    19681 atcgatgata ctttgttatt tactagccaa tattttcagt acggcaaaga atatataact
    19741 ccaggctcat ttgatttttt gcataagcaa aaattttggg acttggtcgc taaacgggga
    19801 gatcaggatt ctattccaaa agagtatgca aagcaactaa tcgcaatgca tcaaaaacga
    19861 ggagataaaa ttgtctttat tactggccga actcgaggat cgatgtataa aaaaggtgag
    19921 attgataaaa cagctaagtc actggctaaa gattttaagt tagacaagcc aatagctatc
    19981 aattatacag gagataaagc tgtgaagccg tatcagtatg ataaaacata ttatataaag
    20041 aaaaacggct cacaaattca ttacggagat agtgatgaag atataaatgc tgccaaagag
    20101 gcaggtgcaa gacctattcg cattttaaga gctcctaatt caaccaatct tcctttgcca
    20161 aaagctggag gatacggaga agaggtttta gaaaattcgg cttattagtc aaatatttgt
    20221 gtaagaaagg aagtaacagt aatttctttc atcaccccac tgagtaacca atagcccagt
    20281 gggttttttg ggttacagaa atcagttcta aaaaagaatc actggtaact taaggttgtc
    20341 tttgatacaa tggtaacagt gtatttaaaa gaaagagagg acaacatgga aaaccataaa
    20401 aatgaattca ccttttccaa caaatcaatt attgcctatg tttggcgtgg tgttgtggtt
    20461 ggtattattg ctggtgttat tgttagttta ttccggttgt taattgaagt gacagctgac
    20521 tgggtgattg aatggtaccg atacgctcat atcaattcgc tgttgctact tcctatacta
    20581 agtgtcagtt tgttagctgt tctttttgta ggttttttag taaagtctga ttctgatata
    20641 aaaggatcag ggatccccca tgtcgaagga gaactaaagg ggctaatgtc cccagattgg
    20701 tggagtgtcc tttggaaaaa atttttagga ggaatcatgg ctatttctat gggatttatg
    20761 ctcggtcgtg agggtccttc gattcagtta ggtgctatgt cagccaaagg attagctaag
    20821 tttttaaaat cgagtcgttt ggaaaagcga gtgctaattg ccagcggagc agcagcaggg
    20881 ctatcagcag cttttaatgc tccaatagca ggcctcttgt ttgttgttga agaaatttac
    20941 catcattttt cgcgtttaat ttggattaca gcgctagtgg ctagcttagt ggctaatttt
    21001 atttctctga atatttttgg attgaaacca gtcttagcaa tgtcagaggc gatgcctttt
    21061 ttaggactca atcaatattg gttgttgctt ttacttggat tatttctagg ctgcttaggc
    21121 tatttatatg agatagttat ccttaatttt aataaacttt atgttatttt agggagttgg
    21181 ttacatctgc cagattattt ttacggtatt attatggttt ttctaatttt accgattggc
    21241 tattatttac cacagttact tggaggagga catggtttaa tactttcttt atccaatcaa
    21301 caattgcctt tgatgactat cttcttttat tttattattc gatttattgt tagtatgttt
    21361 agttatggaa gtggcttacc tggaggtatt tttttaccta ttttaacttt aggtgctttg
    21421 gcaggcctat tatttgggca aatagcttct caattaggtt tattgaacca atcttttctt
    21481 tctctttttt tgatattagg gatggcaggg tattttgcgg caatttcaaa agcaccactg
    21541 acaggcatga ttttggtaac tgaaatggta ggtgatttga aacccttgat ggccatagct
    21601 gtagttactt ttgtctccta tttagtgatg gatttgttaa atggacagcc aatttacgaa
    21661 gctatgctag ataagatggc aatgaagcat ccaactaatc ttgttgaacc aacattaatt
    21721 gaattgactg ttggtgataa gattgcaggg aaatatgtta aagagttaaa gcttccagaa
    21781 aatgtcttaa ttacaaccca aattcaccat caaaaatctc aagttgtgtc aggtaacacg
    21841 cgccttttat caggagcaac tatctttttg gtcgttaatg aagctgatac aggttttgtc
    21901 cgtgaggtat tgatgtaggt attaatttat cacaattcgg aaagttcgag cttgtctttt
    21961 agactaagtc ttcgaacgtt ttactgctag agtttcatct gaaccaaagt gaaacgcttt
    22021 tgatgaagtc aagtaggctt tttgttatac taacaataaa gataagctaa ggaggctgag
    22081 atgttagaaa ttgtttcaga agagctacgt cactatcaag aacaaaaatt gattgagtac
    22141 cgtaacaaaa atcagttagc cccaaaagga ggcattgtat ttgcaggtga ttctctcatt
    22201 gaattttttc ctttaaaaaa agcttttggt tcatgtttgc ctattattaa tcgaggtatt
    22261 gctgggatag atagtcagtg gttattgcgc catttttctg tccaaattac tgatttagag
    22321 cctaaacata tttttttatt aattggttgt aatgatatcg ggcttggata tgataaatgt
    22381 catattgtca agactattgt agagcttatt agccagattc gtagtcattg tgtctatagt
    22441 cagatttatc tcttatcttt attaccagtt tccaacaatc cccgatatca gaagactgtc
    22501 aaaataagaa caaatgctat gattgatgct attaataaag atttagcaat gattccaact
    22561 gtagaattta ttaatcttaa tacttgtctt aaagacgaaa aaggtggttt atcagatgag
    22621 aatactctag atggtttaca tcttaatttt ccagcttatg ctaaactagc tgaaattatt
    22681 aaatcttata tctagcaaat aaatgtacta atagcgatga ggcaagaagt cagatagcag
    22741 atggttcatc aatcaattaa gaaaaaagtt atcaagatac cattaaaaat agttgctcaa
    22801 agttctttca aatcaaaaga ttatgatatc gctatgttga gttttagtgt ataatgataa
    22861 ttaaaggagt taccatgaaa tttgaaaaaa aacaagtctt ctatttagtc cttacgttta
    22921 tcttatgcta tgggatccta gcaaactggc gaaatggaac ggctatcgtc acgactattt
    22981 acaaaacaag ccttcctttt ttttatggag cagcaggtgc ctatattgtt aatattgtaa
    23041 tgagcgctta cgaaaaggta tatgtttata tctttaaaga ctggtcacat gtcttaaaag
    23101 taaaacgggg tatttgttta ctgttagcgt atttgacatt ttttatttta attacttgga
    23161 ttatttccat tgtcattcca gacttaatta caagtattag tactctaaca aaatttgata
    23221 ctataacgat acaagaagtt gttaacaatc ttgagcacaa taaactgtta gcacgtacta
    23281 ttcagtatat tggtggcgat ggcaaactta cagagacgat tgctaactat agtcaacagt
    23341 tattaaagca atttcttact gttttgacaa atattttaac atctgtcacg gttattgctt
    23401 ctgcaattat taatcttttt attagttttg ttttttcgtt atacgtttta gcaagtaaag
    23461 aagatctttg tcgtcaggga aatactttag tagatactta tactggtaag tacgctaaac
    23521 gcattcatta cttgttagag ttgttgcatc agcgttttca cggatttttt gttagtcaga
    23581 ccttagaagc tatgatttta ggttcgctga ctgctagtgg catgtttata ttaagattac
    23641 catttgcagg gactattggc gttttagtag cttttacagc attgattcca gttataggtg
    23701 cttcaattgg agcagctatt ggatttattt taattatgac tcagtccatg tcacaggcca
    23761 ttatttttat cattttttta attattttgc agcagattga aggcaatttt atttatccga
    23821 aagtagttgg tggatcgatt ggattaccgg ctatgtgggt attaatggca attacaatag
    23881 gcgcttcttt aaagggaata gttggtatga ttattgcagt tcctttagca gcgacacttt
    23941 atcaagtgat taaagataat attcaaaaaa gacaagctat tcaaaaaaaa caagtttcct
    24001 aaaaggaact tgtttttttg tcgaataaaa agatggaggt aatatgataa atgtattcta
    24061 taaaatgtga tgataataaa gccatgccaa gagaacgttt gatgcgacta ggagcagagt
    24121 ctctaagtaa tcaagaatta ttagcaattt tattacgaac aggtaataaa gaaaagcatg
    24181 tcttagagct gtcatcctat cttttatcgc atttagacag tctggcagat tttaaaaaga
    24241 tgtctttgca agaattacaa catttggcag gtataggaaa agttaaagcg attgaaatta
    24301 aagctatgat tgagttggtt tcccgaattt tagcgacaga taagacatta actgatagcg
    24361 tattaaccag tgttcaggtc gctgaaaaaa tgatggcagc tttaggagat aaaaaacaag
    24421 agcatttagt cgtattgtat ttagataatc aaaatcgtat tattgaagaa aaaactattt
    24481 ttattgggac tgtccgacgt tcacttgcag aaccaagaga aattttatac tatgcctgta
    24541 aaaatatggc gactagtctc attgttattc ataatcatcc ttcaggaaat attgaaccta
    24601 gttctaacga ttattgcttt actgaaaaaa taaaacgatc atgtgaagat ttaggcatta
    24661 tctgtctaga tcacattatc gttagctata aagattatta tagttttcga gaaaaatcaa
    24721 ccctttttta agtcagaagt cattgacgaa taagcggaac aattgtaaat cttcatctcg
    24781 aacaccttgg agaagttcag gatgccactg aacacctaaa aaaggaatgg catcgttggt
    24841 tgatatgact gcttcgatgg taccatcacg tggatcccta gcgattactt ttaaatcctt
    24901 agcaacagtt tttaaacttt ggcgatgaaa agaattaatt aatgtcttat gaccataaat
    24961 aggatataag atagagtctg gctcaataat catttcgtgt gataagaaat cagaaggcgc
    25021 ttcttgccaa tgtgagtcaa tgtgttggtt aagatttcct cctaaggcaa cattcattaa
    25081 ctgtgtacca cgacaaatcc ctaagattgg tttttttaat gttatagcct ccttgatgat
    25141 agctagctca aatgtgtctc gctctggtga aaaatcatca tcaaaagcag ccttctcttc
    25201 ttgataatat tttgggtcaa cgttttgccc accaattaaa atgattttat caaccataga
    25261 tacataagtt ttagcggcgg cttcatcacc aatgggtaaa agaagcggca gccccccaga
    25321 ttgagtgact gcctgtacaa atccagtagg tgcatatgac catgggagat tatccaaagc
    25381 catatttagt ctttgatttg cagttattcc aataatcggt ttggtcatta tacctcctta
    25441 atctagatga ttttgattca taaaatagag tagtgtctgg agctcactgg tcaaatcgac
    25501 agattgaaca ataactcctt taggaacttg taggtgaaca ggagcaaaac tcaagattcc
    25561 tttgattcct gcttcaataa gttgatcagt aacttcttga gcatgaatgc tgggaaccgt
    25621 taagatagcc gtttcaatgt cagtgttcgc aatccgttct ttgacagatg agataccatg
    25681 gactggaata ttatcagctg ttttagtacc aacaagagcg ttatcatcgg tatcaaaacc
    25741 catggcaatt tgcatcttat tacgatcatg gaagcggtaa tgtaatagag cacgccctat
    25801 attaccgcat ccaactaaga taacgtttgt tgtagagtga tcattaagca agtcagcaaa
    25861 aaaattcatc aatttggtaa catcatagcc aaacccacga cgccccaatt ctccaaaata
    25921 agaaaagtca cggcgtacag tagcagagtc aattcccatt gcatctgcaa tttgtttaga
    25981 actggctttt tcaacttggt cagcatggaa tcgtttaaaa atacggtaat aaagtgataa
    26041 gcgctttgca gtcgcttttg gaatagattt gtcaataacc actattttac tccttgtaga
    26101 tttctcgtta aatatgtctg tctttattgt aacaaaaaga ttgtgaaaaa tgcaacattt
    26161 tgattgtttt tgtatgagtt aaaaaagcta aaatt
//
LOCUS       DAUGJR010000025        25227 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUGJR010000025 DAUGJR010000000
VERSION     DAUGJR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25227
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.025"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(527..913)
                     /gene="rplQ"
                     /locus_tag="VH800_001088"
     CDS             complement(527..913)
                     /gene="rplQ"
                     /locus_tag="VH800_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEQ8362163.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(928..1866)
                     /locus_tag="VH800_001089"
     CDS             complement(928..1866)
                     /locus_tag="VH800_001089"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEQ8362164.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1912..2295)
                     /gene="rpsK"
                     /locus_tag="VH800_001090"
     CDS             complement(1912..2295)
                     /gene="rpsK"
                     /locus_tag="VH800_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEQ8362165.1"
                     /translation="MAKPTRKRRVKKDIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2313..2678)
                     /gene="rpsM"
                     /locus_tag="VH800_001091"
     CDS             complement(2313..2678)
                     /gene="rpsM"
                     /locus_tag="VH800_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEQ8362166.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2696..2812)
                     /gene="rpmJ"
                     /locus_tag="VH800_001092"
     CDS             complement(2696..2812)
                     /gene="rpmJ"
                     /locus_tag="VH800_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEQ8362167.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2838..3056)
                     /gene="infA"
                     /locus_tag="VH800_001093"
     CDS             complement(2838..3056)
                     /gene="infA"
                     /locus_tag="VH800_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEQ8362168.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3174..3812)
                     /locus_tag="VH800_001094"
     CDS             complement(3174..3812)
                     /locus_tag="VH800_001094"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEQ8362169.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEEFGIAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3962..5266)
                     /gene="secY"
                     /locus_tag="VH800_001095"
     CDS             complement(3962..5266)
                     /gene="secY"
                     /locus_tag="VH800_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEQ8362170.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5283..5723)
                     /gene="rplO"
                     /locus_tag="VH800_001096"
     CDS             complement(5283..5723)
                     /gene="rplO"
                     /locus_tag="VH800_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEQ8362171.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5937..6119)
                     /gene="rpmD"
                     /locus_tag="VH800_001097"
     CDS             complement(5937..6119)
                     /gene="rpmD"
                     /locus_tag="VH800_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEQ8362172.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6134..6628)
                     /gene="rpsE"
                     /locus_tag="VH800_001098"
     CDS             complement(6134..6628)
                     /gene="rpsE"
                     /locus_tag="VH800_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEQ8362173.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6647..7003)
                     /gene="rplR"
                     /locus_tag="VH800_001099"
     CDS             complement(6647..7003)
                     /gene="rplR"
                     /locus_tag="VH800_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEQ8362174.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7108..7644)
                     /gene="rplF"
                     /locus_tag="VH800_001100"
     CDS             complement(7108..7644)
                     /gene="rplF"
                     /locus_tag="VH800_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEQ8362175.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7847..8245)
                     /gene="rpsH"
                     /locus_tag="VH800_001101"
     CDS             complement(7847..8245)
                     /gene="rpsH"
                     /locus_tag="VH800_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEQ8362176.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8396..8581)
                     /locus_tag="VH800_001102"
     CDS             complement(8396..8581)
                     /locus_tag="VH800_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEQ8362177.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8597..9139)
                     /gene="rplE"
                     /locus_tag="VH800_001103"
     CDS             complement(8597..9139)
                     /gene="rplE"
                     /locus_tag="VH800_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEQ8362178.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9163..9468)
                     /gene="rplX"
                     /locus_tag="VH800_001104"
     CDS             complement(9163..9468)
                     /gene="rplX"
                     /locus_tag="VH800_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEQ8362179.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRIGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9547..9915)
                     /gene="rplN"
                     /locus_tag="VH800_001105"
     CDS             complement(9547..9915)
                     /gene="rplN"
                     /locus_tag="VH800_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEQ8362180.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9940..10200)
                     /gene="rpsQ"
                     /locus_tag="VH800_001106"
     CDS             complement(9940..10200)
                     /gene="rpsQ"
                     /locus_tag="VH800_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEQ8362181.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10226..10432)
                     /locus_tag="VH800_001107"
     CDS             complement(10226..10432)
                     /locus_tag="VH800_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEQ8362182.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10442..10855)
                     /gene="rplP"
                     /locus_tag="VH800_001108"
     CDS             complement(10442..10855)
                     /gene="rplP"
                     /locus_tag="VH800_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEQ8362183.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10859..11512)
                     /gene="rpsC"
                     /locus_tag="VH800_001109"
     CDS             complement(10859..11512)
                     /gene="rpsC"
                     /locus_tag="VH800_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEQ8362184.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11525..11869)
                     /gene="rplV"
                     /locus_tag="VH800_001110"
     CDS             complement(11525..11869)
                     /gene="rplV"
                     /locus_tag="VH800_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEQ8362185.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11885..12163)
                     /gene="rpsS"
                     /locus_tag="VH800_001111"
     CDS             complement(11885..12163)
                     /gene="rpsS"
                     /locus_tag="VH800_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEQ8362186.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VH800_001112"
     CDS             complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VH800_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEQ8362187.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13153..13449)
                     /locus_tag="VH800_001113"
     CDS             complement(13153..13449)
                     /locus_tag="VH800_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEQ8362188.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VH800_001114"
     CDS             complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VH800_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEQ8362189.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VH800_001115"
     CDS             complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VH800_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEQ8362190.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILVKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14938..15246)
                     /gene="rpsJ"
                     /locus_tag="VH800_001116"
     CDS             complement(14938..15246)
                     /gene="rpsJ"
                     /locus_tag="VH800_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEQ8362191.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15447..16739)
                     /locus_tag="VH800_001117"
     CDS             complement(15447..16739)
                     /locus_tag="VH800_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEQ8362192.1"
                     /translation="MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSG
                     VSIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGL
                     LSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
                     VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRP
                     LDKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAM
                     ATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTD
                     AQRSAMIVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIG
                     VVWQYGLIGVWMATVLDNTSRWFILSKHFKKYQEITFH"
     gene            complement(17127..18143)
                     /gene="adhP"
                     /locus_tag="VH800_001118"
     CDS             complement(17127..18143)
                     /gene="adhP"
                     /locus_tag="VH800_001118"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEQ8362193.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18395..21037)
                     /gene="adhE"
                     /locus_tag="VH800_001119"
                     /gene_synonym="adhC"
     CDS             complement(18395..21037)
                     /gene="adhE"
                     /locus_tag="VH800_001119"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEQ8362194.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21346..23121)
                     /locus_tag="VH800_001120"
     CDS             complement(21346..23121)
                     /locus_tag="VH800_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEQ8362195.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLFWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMIGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGSLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSQIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23118..23519)
                     /locus_tag="VH800_001121"
     CDS             complement(23118..23519)
                     /locus_tag="VH800_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362196.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKDGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23542..23979)
                     /locus_tag="VH800_001122"
     CDS             complement(23542..23979)
                     /locus_tag="VH800_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEQ8362197.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            complement(24117..25115)
                     /gene="ruvB"
                     /locus_tag="VH800_001123"
     CDS             complement(24117..25115)
                     /gene="ruvB"
                     /locus_tag="VH800_001123"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEQ8362198.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25162..>25227)
                     /locus_tag="VH800_001124"
     CDS             complement(25162..>25227)
                     /locus_tag="VH800_001124"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEQ8362199.1"
                     /translation="FAALLSFKVVQELSAVDWWRL"
BASE COUNT         7445 a         5314 c         4452 g         8016 t
ORIGIN      
        1 aattttgttg gaaacggctt aaagtgacag attttaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt agaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttgcgat gcaagttttt ttcggacatt taaacgaggg
      181 gattacaccg tttatttgcc catgagaggt ctttaaacac ctgcataagg ttttcttatt
      241 ctgatgacct tattgtctct gagaaaactt tataaacgca tcagaagagg cttctgtgtt
      301 attgttttgc tcagcttaaa agcggggggt gttcacctca taatacaaca aaacgcctgc
      361 ttataaaaag tttctatagc ttagatacct ttcataaaca agcgttacat attaacaata
      421 tgatgagtgt tcccgctagg aaaaatccta gcggtagacc agagctagac taagaataat
      481 ctctcgatta ctccatcatc ataacactca acaaaattga taaaaattaa actaattcaa
      541 taattgccat tggagcagca tctccacggc gtggttctgt tttaagaata cgagtgtatc
      601 caccgttacg ttctgcataa cgaggtgcaa tttctgagaa aagtttttga agagctgtcg
      661 ttgatgtgta tttatcggta gcttcatcat aattttctga tgcgatttcg ttacgaacgt
      721 atgcagctgc ttggcgacga gcatgaagat caccacgttt accaagagta atcatttttt
      781 caactgtttt acggatttct tttgcacgtg cttctgtcgt tacaattgat tcgttgatca
      841 aaagatctgt cgtcaaatca cgaagcattg ctttacgttg tgagctagtg cgtcctagtt
      901 tacggtaagc cattttgtcc tcctatatta tttatcgttt tttagtccga gacctaagtc
      961 agcaagttta accttaactt cttcaaggct cttacgtcca agattacgga ctttcatcat
     1021 ttcaggctca gatttttctg ttaaatcgaa gacagtgtta atgcctgcac gttttaaaca
     1081 gttatatgag cgtacggata aatcaagctc ctcgatggtg cggtcaagta ccttttcatc
     1141 gttcactttt tcagtttctt tcattacttc ggtagctttt gcaacctctg ttaaatcagt
     1201 aaacaggttt aagtgttcga tcaaaactcg agcagataga cctaaagcat cttcaggaat
     1261 aattgttccg tttgtcatga tttcaatcgt taatttatca aagccatcat tgctacctac
     1321 acgggcaggt tcaacttgat aattaacttt tttaactggc gtatagattg aatctactgc
     1381 caatgtaccc acaggtgcat catctttttt gttgccttct gctggcacat aaccacgttt
     1441 tttagcaaca gtcattgttg cacgtagaga atgtccttca gcgattgtaa aaagataatg
     1501 atccgggtta acaagttcga tatcactgtc agtaagaata tcaccagctg ttacctctgc
     1561 tggtccttct acttcaagtt cgataatctt ttcgtcttcg acgtatgatt tcacagcaag
     1621 tcccttaaca ttaaggataa tttgcatgac atcttcacgt acacctggga ttgtatcaaa
     1681 ttcgtgtagt actccatcaa ttttaattga tgttactgct gcacctggaa gtgaagacaa
     1741 gagtacacga cgaagagaat tacctagagt tgttccgtag ccacgttcaa gtggttcgat
     1801 gacaaatcta ccgtaatctt tattttcatc aatttttgtt attattggtt tttcaaactc
     1861 aatcattttt tcacccctcg aaacgaaact tgtgtactat ttgttatatg attatacacg
     1921 acgacgtttt ggaggacgag caccattatg tggcacaggg gtcacatcac gaattgcagt
     1981 tacttcaaga cctgcagctg ctagagcacg aatagctgat tcacgacctg aaccaggacc
     2041 ttttacagtc acttcaacag tttttagtcc gtgttcttgt gcagattttg cagcagcttc
     2101 tgcagccatt tgagcagcaa atggagtaga tttacgagaa cctttgaaac caagagcacc
     2161 agctgatgac catgcaagag cattaccatg cacatctgta atcataacaa tagtgttatt
     2221 aaatgtagcg tgaatgtgtg caacaccaga ttcgatgtcc tttttcacac gacgtttacg
     2281 tgttggttta gccaattgtt ttacctccta ttttattttt tcttacctgc aatcgcaaca
     2341 gctttccctt tacgagtgcg agcattgttt ttagtatttt gtccacggac aggaagtcca
     2401 cgacgatgac ggattccacg gtatgaaccg atttccatca aacgtttaat gttcatgttt
     2461 acttcacgtc gaaggtcacc ttcaactttg attgcatcca cttcacgacg gatagcatct
     2521 tcttgatctg atgttaaatc tttaacacgg atatcttcag aaatacctgc agctgctaag
     2581 atttttttag atgttgcaag accaattccg taaacataag taagtgaaat tactacgcgt
     2641 ttatcatttg gaatatcaac tccagcaata cgagccattt tttctccttt ctattttatc
     2701 cttgacgttg tttgtgtttt ggatttgtcg gacaaattac cataacacga ccattacggc
     2761 gaataacttt acagtattcg caaattggtt taaccgatgg tcttaccttc atgttttaat
     2821 ccctccaatt atttcgatta tttaaagcgg tatgtgatgc gtccacgtgt caagtcataa
     2881 ggactcattt ctactgtaac acggtcacct actaaaatac gaatgtaatt tttgcggatt
     2941 tttcctgata cagttgctag aatttgatgt ccattttcca attcaacagt aaacattgca
     3001 tttggcatcg tttctactac tttgccttca atttcaatca cgtcttcttt tgccacgcaa
     3061 aagtaccccc taaatttcga tttgatgtcc tctgagcaca gaggtaacaa ttataagtca
     3121 gactaaacta gtatatcatt actaatctac ttatgcaagt agatttgtat aatttatttg
     3181 agttctagca acgctttttc aacatctgca aaaacgtctg ttatttcttg attaccttca
     3241 atatctgtaa caagaccaag cttacgatag tgttcaagaa taggttctcc ttgagccata
     3301 ttgacgtcca aacgacgttt aacagtttca ggcttatcat cttcacgttg atagtaatct
     3361 tcttctttat aatctactgg tgggttgaac actttatgga acgtttcacc agttttacga
     3421 ttgataatac gaccactcaa acgctctaca agacatgatg gatccacttt aatattaata
     3481 acaccatcta agcggagtcc tagttcttca agtgttgcat ctaaggcgtg tgcttgttca
     3541 atagtacgtg gatacccatc aagcaaaaaa cctttttctg cgatatcatc ctcagctaag
     3601 cgctctttta caatcccgtt tgtgacttca tcaggaacca attcaccttt atcaatataa
     3661 cttttagcta aacgtcccat ttcggtttga ttagccattg cggcgcggaa catatcccct
     3721 gttgagatgt gagcaatacc aaattcttca acaatcttag ctgcttgggt ccctttacca
     3781 gctcccggca aacccatgat taaaagattc atcttttcct cctcttttaa aataaataca
     3841 tagtaggaaa ttattttcct tggtttttgt tttcaaatgg caacaagaaa tcgtttgatg
     3901 ataaccaagt cttattgtca tttaaaaaca aaatagaagg ttgacaatgt caacctgtat
     3961 tctattctgc tgtattcata aatccgacat attttctctt tagaagatat ccctcaagct
     4021 gtttcatacc ttcgatacca gttgaaatca aaatgagcaa actagttcca cctaaagcaa
     4081 tactagaaga aaggttgaga gcttgttgtg ctgctattgg cgctaaagag ataaatgcta
     4141 agaagatagc tcctacggtt gctagttttt ttagcaatgc ggacataaat tgttctgtct
     4201 cacgtccagg gcgaacactt ggtatatatg aggaattctt ctgaagattt tctgctgtct
     4261 tctcaggatt aacttgtaca aaggtataga agaatgagaa caatataatc aacaaggcgt
     4321 aaactatcat tccgactgga gtttgataat taaaaatttc ttgcaaacgg tttaaccacg
     4381 gtaaatctct accattttga acaaaaggaa taatcgtact tgggatagtt gtaatcgagc
     4441 tagcaaagat aacgggaata acgccggctg gatttacttt taatggaaga tatgaacttg
     4501 taggtgcacc ttgcattagc tttgtgtatt ggattggaat tttatattcc gcttgttgga
     4561 catatgttgt aaagaaaaca atagcaagaa cagctatgat taaaatccca acaatgagat
     4621 aagacgagtg taaatcactt gccttaacat ttacaaaata gtcttcacga attgttgcaa
     4681 ttgcacttgg aatagacgaa ataatacccg caaagataat cattgatacg ccattaccaa
     4741 atcctttatc tgtgatttgt tctccaagcc aggtaacaat aacgctacct gttgtcagta
     4801 atgccccgat cagtaaatat gttttgatgt ctggtgtctt aacaagtgca acgttcgaca
     4861 aagtattaaa ccctgcagtg ataccaatgg attgggcaaa agccaaaaca agtgaaatat
     4921 agcgcgtcgc ttgatttaat ttacgacgtc caacctcacc ttgtttgccc cactcaacaa
     4981 acttaggtaa aatatccatc tgcaataact gaacaacgat agaagcagta atatatgggc
     5041 taacccccat tgaaaatact gagaaatttc tcatcgcatt accactaact aagtttaaca
     5101 tatttaagaa agggagttca cttaattgct ctaagctctt ggcatttaca ccaggtacgg
     5161 taatatgtgt cccaattcgg aatacaagaa tgataaatat agtaaagaaa attttattcc
     5221 gtacagtctt tatctttaac gcgtctttta gtatttttaa gaacataatg agtatcccct
     5281 cattagatga cttcgattga accaccttta gcaataatag ctgcttcagc agattttgag
     5341 aacttagctg cttttacagt caatttttta gtcaattcac cgttaccaag cactttaacg
     5401 cctgattttt cagctcggac aataccagca tcttttaaaa tagccggagt cacttctgta
     5461 ccatcatcaa aaacattcag ttgatcaaga ttcacaagtg catattcttt agtattaata
     5521 tttgtaaagc cacgttttgg aatacgacgg aacaatggtg tttgtccacc ttcaaaacct
     5581 aaacgtacac cgccaccgct acgagctttt tgaccttttt gaccgcgacc agatgtttta
     5641 ccattacctg atgatgtccc acgaccaaca cggttacgta ctttacgtga gccttcagca
     5701 gcttttaatt catgaagttt cattttttct cctttttttg taaaatgcta gcgcctctat
     5761 gagggaaaag gactccctat agaaactcgc ctatacatta atgatactta agttatccaa
     5821 aataacttaa tacagatacg cactaaccga ctactgtttg ttgccaaaaa gcaaactaca
     5881 agagtcggtt ttgtgctcgt ttttaattat gaaatcagag atttcacagt tataacttat
     5941 ttaacatctt caacggtaac caagtgagaa atagctgtca ccataccacg gatagcagca
     6001 ttatcttctt tgactactga agagtttaat ttaccaagtc caagagcaac aacagtttta
     6061 cgttgttctg gcttacgtcc gataggagac ttagtcaaag taattttaat ttgagccatg
     6121 atgatcccct ttcttatgct aagtcagaaa ctgagatgcc acgaagtgcg gcaacttctt
     6181 ctgcacgttt aagttgtttc aatccttcaa cagttgcacg aacaatgttg attggagtgt
     6241 ttgaaccaag agattttgaa gtaatatcag caacacctgc taattcgatg acggcacgaa
     6301 ctgcaccacc agcagcaact ccagaacctt ctacagctgg tttcaataat actttagctc
     6361 caccgaagtt agtgtaaact tcgtgaggga ttgttgtacc aaccattggt acttcgatca
     6421 tgtttttctt agcagcttca actgctttac ggatagcttc tggaacttct tgagctttac
     6481 cagtaccaaa tccaacacga ccatttccat caccaacaac tacaagagct gcaaagcgaa
     6541 gacgacgtcc acctttaaca acttttgtaa cgcggttaat cgcaacaacg cgttcttcaa
     6601 gttcaactgc attatcttta aatgccatta ttttgtgtcc tccctattag aatttcaatc
     6661 cgttttcacg agctgcatca gccaaggctt taacacgtcc gtgatagaga tatccaccgc
     6721 ggtcaaacac cacttcagaa atacctttag ccactgcacg ttcagcaaca agtttgccga
     6781 ctacaacggc ttgttctgtt tttgttcctt tagaaacgtc tttatcaaga gttgatgcac
     6841 ttgcgagcgt tacacccgct acgtcatcaa taacttgagc gtagatgcct gtattagaac
     6901 ggaatacgtt caaacgtggg cgatcagcag ttccagagag tttaccgcgg acgcgacggt
     6961 ggcgtttttg gcggattttg tttttatctg gtttcgaaat cacaattttc acctcttaat
     7021 tttaatcaat ttgtctcatt gacaagttgt cgattgaact tatcgagcat gttaaggtgc
     7081 aatacttccc atacccgact aagaacatta tttacctgtt ttaccttctt taaggcgtac
     7141 gtattcacca acgtaacgga tccctttgcc tttgtaaggc tctggtgaac gcaagctacg
     7201 gatgtaagca gctgtttgac caacaacttc tttgttgatt ccttcaactg agattgaagt
     7261 tgggttagca acagtgaaag taattccttc tggagcttca acttcgtctt ggtgagattt
     7321 acctactgaa aggacaagtt tagtaccttg aagttgagca cggtaaccga cacccttcat
     7381 ttcaagatct tttttgaaac cttcagaaac acctacaacc atgttattca agttagcacg
     7441 ggttgtacca tggattgttt tcatttcttt tgagtcgtta ggacgtacaa ctgtgatttc
     7501 agtcccttca actttgattt caatattttt gttgaactca cgagtgagtt cgcctttagg
     7561 gcctttaaca gtaataacat tgttgttatt tgttaattca acgcctgcag gcatagtaat
     7621 tactttatta ccaatacgtg acatgtttat tttctcctgt taaattgtca agccgcatag
     7681 cgactagttt tcacgggggt ttgatagaat gatatacttc aatttatatt tcaaaattga
     7741 acacgagctg tggtctgtgt gaaaaagata aatcttcctt gagtgtaaac acgctacgtc
     7801 agatttccta ttttcacttt gtccacgacg ctcttagtat cttaaattac caaacgtaag
     7861 cgatcacttc tccaccaaca ttcttttggc gagcttcttt gtcagtcaaa agaccttctg
     7921 atgttgaaat gattgcaatt ccaagtccgt taagaacttt aggcatgtca tcacgttttg
     7981 cgtaaacgcg aagacctggt tttgaaatac gttttaagtt agtgataaca cgttcaccat
     8041 tttttccgta ttttaagaac acacgaatga tgccttgttt atcatcttcg ataacttcaa
     8101 cattttttac aaaaccttca cgtttaagaa tctcagcaat ccctttttta atgtttgaag
     8161 caggtacttc taacacttcg tgttttactt gattagcatt acggatacgt gttaaaaagt
     8221 ctgcaattgg gtcagtcata accatttttt atattctcct cttactagca gtttgatgct
     8281 atcacttact agttaatgtt gtccttaaag gactttggta tcagcttatg ctcacaccgt
     8341 tttaattaag cacaagactt aatctgaaga acaaattaag ttttgtgtca tatttttacc
     8401 aagaagcttt gacaacacct ggaatttgac ctttgtaagc caattcacgg aagcaaacac
     8461 gacaaagttt aaacttgcgg taaactgaat gtggacgtcc acatttttca cagcgagtat
     8521 aagcttgtgt agagtgtttt gcaggacgtt tgttcttagc aatcatagat tttttagcca
     8581 atttatttac cccctattat tttgcaaaag gcattccaag gcccttaagc aattcacgtg
     8641 attcttcgtc agtatttgca gtagtgacga ttacaatatc aagaccacgt actttatcaa
     8701 catcatcaaa gctgatttct gggaagataa gttgttcttt cacaccgaga gtgtagtttc
     8761 cgcgtccatc aaacgatttt gttggaacgc catggaagtc acgtacacga ggaagtgaaa
     8821 cgctaaccaa tttgtctagg aattcgtaca tacgttcgcc acggagggta acttttgcac
     8881 cgatcgctac accttcacga agacggaagc cagcgattga tttcttagct ttagtaataa
     8941 gtggtttttg acctgagata agtgctaatt cagctgcagc tttctctagg ttttttgcgt
     9001 tggatacagc atcaccaaca cccatattga gaacaatttt ctcaactttt ggcacagcca
     9061 taactgatgt gtaattgaat ttctctgtca acgcaggaat tacttcgtta gtatattttt
     9121 cttttaaacg atttgccatt atgcttctcc tttccttcgt gattaatcaa gcacttcgcc
     9181 tgattttttg ctgtaacgta cttttttacc gtcaacaact ttataaccaa tacgtccagc
     9241 tacaccattt ttatctaata cttgaacatt agagacatgg ataggtgctt ctttttcgac
     9301 gatagctcct tgaggatttt cagtgttagg tttttggtgt tttttaatca ttccaacacc
     9361 ttcaacaata actttgttaa cttttggaag tgctttaaga actacagctt cagtgccttt
     9421 gtccttgcca gcaattacgc gaactttgtc gccttttttt acaaacattc tggtttctcc
     9481 tattatttct tacgccccga tgggcaccct aggaaaacct aggggactac gtttgttaat
     9541 ctgagattaa agtacttctg gtgcaagtga tacgatcttc atgtagccac cctcacgcaa
     9601 ttcgcgtgca actgggccaa agatacgagt tccgcgagga gttttatcat cacggatgat
     9661 tacagcagca ttgtcgtcaa atttgatgta tgaaccgtct ggacggcgtg caccagtttt
     9721 tgtacgaacg ataacagctt taaccacatc acctttttta actgctccac caggagtagc
     9781 ttgttttaca gaagcaacga ttacgtcacc gatgttagcg aatttacgtc ctgaaccacc
     9841 aagtactttg atagtcaaga tctcacgagc accgctatta tcagcaactt tcaagcgagt
     9901 ttcttgttga atcatttcaa ttttctcctt ttagtttgat tagataataa cagctttttc
     9961 cactacttcc acaagacgga aacgttttgt agctgaaagt gggcgagttt ccatgatacg
    10021 aacgatatcg ccttctttag caacgttgtt ttcgtcatgt gctttatatt ttttagaata
    10081 gttgatacgt ttaccataga ctgggtggtt acgtttagtt tcaactacaa ctgtgattgt
    10141 tttgtccatc ttgtcagaca ctacgcgtcc gtaaagagtt ttacgttgat tacgttccat
    10201 ttagaatttc tcctttccca atctattatt tcatttctga ttgcacagtt ttaacacgtg
    10261 caatttgttt cttaacttcg tcaaggcgag cagtcttttc aagttgacct gctgcagctt
    10321 ggaaacgaag atcaaacaat tcttttttga gttcgttttc tttcttagca agttcttctt
    10381 gagacaatcc acgaagctct ttaacaaaat ctttaatttc ttgaagtttc atgtcttctc
    10441 cttattctgc ttcacgtttt acgaatttgc acttaactgg taatttgtgg ctagcaagac
    10501 gtaatgcttc gcgagcaatt tcttcagaaa caccagcaat ttcaaacatc actttaccac
    10561 gtttaactgg tgctacccaa ccttcaggtg cccctttacc agaacccata cgtacaccga
    10621 tagcttttgc agtgtatgat ttgtgtggga agattttaat ccaaacttta ccaccacgtt
    10681 tcatgtaacg agtcatcgca atacgggcag cttcgatttg acggtttgta atccagtggc
    10741 tagttgtggc ttgaagtccg tattcaccga atgaaacttc tttaccacct ttagcctcac
    10801 cgcgcatttt tccacggaat tcgcgacggt gtttaacacg tttaggtact aacatttgtt
    10861 atttgcctcc tttagtgttt ttacgagctg gaagaacttc tccacggtaa atccaaactt
    10921 taacgccaag tttaccataa gttgtgtcag cttcttccca agcatagtcg atatcagcgc
    10981 gaagcgtgtg aagtggaaca gttccttctg aataaccttc agcacgagcg atatcagcac
    11041 cgttcaaacg accagaaact tgagttttaa tccctttagc tcctgcacgc attgtacgtt
    11101 ggattgcttg tttttgagca cgacggaaag caacacgttg ctcaagttga cgagcaatgt
    11161 tttcaccaac aaggtgagca tctaaatcag gttgtttgat ttcgatgatg ttgatgtgta
    11221 cttgttttcc agttaatttg ttaagttgac cacgaagagc gtcaacgttt gcgccacctt
    11281 taccgataac catacctggt ttagcagtgt gaagtgaaac aataactttg tttactgcac
    11341 gttcaatttc aatagttgaa actgatgcgt cagctaattc tttattaatg aatttacgga
    11401 ttgcaagatc ttcatgaagg taatccgcgt attctttttc agcataccat ttcgcatccc
    11461 agtcacggat gattccgaca cgcataccaa ttggatgtac tttttgaccc acgattttac
    11521 ctccttattt ttctgataca actacagtta cgtgagttgt acgtttgttg attggtgaag
    11581 ctgaaccttt cgcacgtgga cggaaacgtt tcattgttgg tccttcgtta gcgaatgttt
    11641 cagatactac caagtttgct ttttccaaac caaagttgtt ttctgcgtta gcaattgctg
    11701 agttaagagt tttctcaata acacgagctg ctttgtttgg agtgaatttt aagattgcga
    11761 ttgcgtcagc aactttctta ccacggataa gatcaagtac taaacgtgtt ttacgaggtg
    11821 aaacacgcac tgtacgagcc attgctttag ctgaagtaat ttctgccatt gtgtcctcct
    11881 cctattaacg acgtgttttc ttgtcgtcag ctgcgtgacc tttgtaagta cgcgttggtg
    11941 caaattcacc aagtttgtga cctaccatgt cttcttggat gtaaacaggt acatgtttac
    12001 gtccgtcata aactgcgatt gtatatccga tgaaacttgg gaaaatcgtt gaacgacgtg
    12061 accaagtttt gattactttt ttcttttcgt cgtttgcttg agcttcaact tttttcatca
    12121 aatgctcatc gacgaaaggt ccttttttaa gactacgtcc cattttgtag ttttctcctt
    12181 taaataatgt accacagcgg cttgaattca agagcaagac tccaaactct accgagttgg
    12241 cggaataaat agcaaagcta ttgtaacgct atttcagcaa gtttttagca acttactaaa
    12301 attatttttc gttacgacga cgaacgataa gtttgtctga tttagctttc ttgttacgag
    12361 ttttaagacc aagcgctggt ttaccccatg gagttgatgg cgctttacgt ccaactggtg
    12421 ctttaccttc accaccaccg tgtgggtgat cgttagggtt cattacagaa ccacgaactg
    12481 ttgggcggat acctttccaa cggctacgtc ctgctttacc aatgttaaca agtgattgtt
    12541 gttcgttacc aacagtaccg atagttgcac ggcatgtacc aagaatcata cgaacttcgc
    12601 ctgattgaag acgaacaaga acgtatttac cttcttgacc aagtacttga gcagaagctc
    12661 cagctgcacg aacaagttct ccacctttac caggtttcaa ctcaatattg tgaacaactg
    12721 taccgacagg aatgtttgct aatggaagtg cgttaccaac tttgatatct gcatctggac
    12781 cagaaacaat acgttgacct acttcaagac ctttaggtgc aatgatgtaa gctttcacac
    12841 cgtcagtgta atgtacaagt gcgatgtttg cagtacggtt tggatcgtat tcgattgttt
    12901 taacaactgc ttcaacgcca tctttgttac gtttgaagtc gatcaaacgg taatgacgtt
    12961 tgtgtccacc accttggtga cgaactgtga tgcgaccatt gttgttacga ccagctttgc
    13021 tcttaagaga aacaagcaat gatttctcag gcgtgcttgt tgtgatttcc gcgaaatcca
    13081 aagaagtcat gttacgacgg ccatttgtcg ttggtttata aactttaata cccacgttat
    13141 ttcctcctta gattattcag cttcagctgc gaacaactcg attgctttag aatcagctgt
    13201 aagagtgatg atagcttttt tagtttttga agtgaaacct gtgtaacgac caacgcgttt
    13261 tgcttttggt ttaacgttaa cagtgtttac acttgcaact ttaactccgt caaaagcagc
    13321 ttcaacagct tgtttgatca aaagtttgtg tgcacgagta tcaacttcga aagtgtattt
    13381 gcctgcttca agagcaatca ttgacttctc agtgataact ggttttttga ttacgtcgta
    13441 caaattcatt atgcaagaac ctcctcaatt gtagagattg cttctttagt aacaagaagt
    13501 ttgtctgcgt tcacgatatc aagaacactt gcagttgctg cagttgcaac agttacgttt
    13561 ggaaggttac gtgcagaaag tgctgcaaat tcatttcctt cttcaacaag aacaagtact
    13621 tttgtatcaa tgctaagagc tgaaagcact tttgcaaatt cagcagtttt tggtgctgca
    13681 aatgaaaggc cttctacagc tacaaattta tcttcagcaa cttttgctga gtaaactgat
    13741 ttcaacgcaa ggcgacgaac tttttgtgga agtttgtatc cgtatgaacg gggagttggt
    13801 ccaaagacaa caccaccacc acgccattgt ggtgagcgga tagaaccttg acgagcgcgt
    13861 ccagttcctt tttgacgcca tggtttacgt ccaccacctg atactgctga acggttttta
    13921 accgcatgag taccttggcg aaggctagcg cgttggctaa ttacaacatc aaaaacaact
    13981 gattcgtttg gttcgatacc gaagatagcg tcgtttaatt caactgagct aacttcttta
    14041 ccagtttggt caaatagttt tacgtttgcc attttaactg ttttctcctt tcttattatt
    14101 tagcagcttt aactgctgac ttgatagtga taagagattt cttagcacct ggtacgttac
    14161 ctttaacaag gataacgttc ttttctggga taacttgtac aatttcaagg ttttgaactg
    14221 ttacacggtt accacccata cgtcctgcca agcgtttgtt tttgaaaacg cggttaggcg
    14281 caacaggtcc catagaacct gggcgacgat ggtaacgaga accgtgagcc ataggaccac
    14341 gtgattgacc atggcgtttg ataacacctt ggaaaccttt accttttgat gtccctgtga
    14401 cgtcaacaac atcaccagct tcaaattgtt ctacagataa ttctgcacca acttctaagc
    14461 cttcaatgtt tttgaattca cgaatgaagc gcttaggagc tgtgtttgct tttgcaacat
    14521 ggcctttggc aggtttgtta ctcaagactt cacgtttgtc atcaaaacca acctgaactg
    14581 cttcataacc gtctgtttca acagttttaa cttgaagcac aacgtttgga gttgcttcaa
    14641 tgacagtaac agggatgaat tcgcctgatt cagtgaagat ttgagtcatt cccacttttt
    14701 tccctaagat tccttttgtc atgagaaaat atttcctttt cttaataata tttcaaaaag
    14761 ttttttacga gcgttttttg tgctcatagc aagatacaaa gagcgtcaaa ctcaaaataa
    14821 aaatagaaaa tctaacacaa aagcttctgt ttcgaggaag atttatcttt ttcatgtaga
    14881 gtttagctcg tgttcaagtt ccatcaaaca ctaactgtac ttgcaaaatc tcaccgatta
    14941 aagtttgatt tctacgttga caccacttgg aagatcaagt ttcatcaaag catcaacagt
    15001 tttttgtgtt ggattgatga tgtctaccaa acgtttgtgt gtacgcattt caaattgttc
    15061 gcgagaatct ttgtatttgt gagtcgcacg aataattgtg taaagactgc gttcagttgg
    15121 aagtggaact ggtccagcaa ctgtagcacc tgtacgtgtt gcagtttcaa cgattttttc
    15181 tgccgctgta tcaagtgtac ggtgttcgta cgctttcaaa cggatacgga tttttttgtt
    15241 tgccatcttt tctcctctcg tctatttacg ataataggct agctcctcaa gaaaaccgac
    15301 acctgttgcg tggcaatgca accgagcgtg tcgcaacctc ttgtatcatt gctaaagctg
    15361 tatttttaca gcaccacaat ataataacag aatcatttag tcattgcaag ctttttaggc
    15421 atttttttca aaaaaaaact accttcctaa tgaaaggtaa tttcttggta ctttttaaag
    15481 tgtttagaga gaataaacca ccgactggta ttatctaaca ctgtcgccat ccagacccct
    15541 atgagtccat attgccaaac cacaccaatc acataaccaa ggccaatgcg aatcacccac
    15601 attcctatgg ttgttgcata gaaaggaagc tttgcttttc ccaaaccctg ccagacggct
    15661 gtataaacta aagtgcctgc cgttgcggga gctcctagta aagaaaaaag taaaacaatc
    15721 atggcagacc tttgagcatc agtattctgt gtaaatagcg gcaagagact aggacctagc
    15781 agataggtca aggctcccat aaccagcatc atgagggtgg ataaaataaa agcttctcta
    15841 ataatatacc ttatctcagt caccttaccg ccccccagtt gcctagccac tagaataatt
    15901 gttgccgttg ccatggctaa gccaggcatg taattaaact gagtcaaggt ttctccaata
    15961 gcattacctg ccaaggccgt tgtcccaaag cgaacaacaa tgccaataat taggacatct
    16021 cctgctctca tcatcaaacg ttcaccagca gcaggtagtg ataaatcaaa aataattttg
    16081 tccaaaggtc tcatcaatcg tttcgcaacc tgtttaatag gaataaactg acaaagtaaa
    16141 aacacaccca ctaaacgaga taaaaccgtc gcccaagcaa caccaagaag accaaatccc
    16201 catacataga tagacaaggc agaaaaaatg gcattgagta cgtttattaa taagctcact
    16261 tgcataggaa tcttaggata cccttgagct cgaacaatag ctcctaagct agttaaaagt
    16321 cctagactaa caatcatacc gccgacaatg gatagatatt gccctccaac caatgttaca
    16381 gaagcttcag ctcctagcca ttctaacacc tgatgatgtc cagcaactga taacaaccct
    16441 aagccgaccg aaaggaggag tgttacttgc aagacacctg ccatatagtt taattgtttg
    16501 ttctgattat tttctccaat acttcgagca atcagactag atacagcagc tcccagcgcg
    16561 ataaagaggg actgataaat actgataatg ttgttagcta tggagacacc agagactgct
    16621 acaagtccaa tttgagccac caggtaatta tcaaccattc ccattaacat ctgtaaaata
    16681 ttttctatca tagaaggcag agctaaagag aaaatttttc ttctattatt atatatcatt
    16741 tatgtcccct aataaaaaat tcttgatcaa acgatttttt caaacacagt cactggactc
    16801 attcagttat tttggtccat taatgaattc ataaagtcta tcttaatagc agagtcccaa
    16861 gatacacgac acttagtgtt acagtaacaa ttgaccacat gccaatcctt aacatttacc
    16921 taacgtttat aactaagaag atgaagaaca aaaggactcc aaacgaattt tttctattat
    16981 ataatatatt cttcatttag caactttcaa tgtatcaaaa tagcactctc gagtcaaaaa
    17041 tgttttctga tactcgagag tgctatttta tttggaatca agtttaagca acttaggctt
    17101 atctcatatt taatacattt gtatgtttag ctgatgaaat ctaagacctt gcgcccttgg
    17161 attaaaccac gttccatttc atcaaagact tctggagcag tgtcaactgg aactttttcg
    17221 acaaccggag caaccagacc ttctgcacca aaggcaaagg cttcttccaa gtctttacgt
    17281 gtccctacaa gtgatccgac cactttgata ccatctaaaa cagtttttac gatagacagt
    17341 tccatgtatt ctgatggaag acctacggct acaactgttc caccggcacg gacactatca
    17401 attgcttggt taaaagcaac tttagaaaca gccgttacca caacaccatg tgctccaccg
    17461 gttttttctt gaatatagcc tggaacatct tcaatttctt tgccgttaac taaaatatct
    17521 gcgccaactt ctttagctaa ctcaagttta tcattattaa tgtccactgc gacaacatgt
    17581 gcattaaaga cttttttagc gtattgaaca gccagatttc caaggccacc agccccaaag
    17641 ataacaatcc attggcctgg agcagcacct gcctctttaa tagctttata agttgttaca
    17701 ccagcacaag taatggaaga agcttgagcc gggtctaaac cttctggaac tttaactgca
    17761 taatcagctg ttactactgc atattcactc attcctccat caacactgta tccagcattt
    17821 ttaacactac gacaaagtgt ctcacgtcct gtagtacagt attcgcaatg accacatcct
    17881 tcaaagaacc atgcaataga gacacgatca ccaaccttta aggatgttac gccttctcca
    17941 atttcttcta ctataccaat accttcgtgc cccaaaatac gtcctggtac ctgaccaaaa
    18001 tcgccatgtg caacgtgtaa atcagtatga caaacgccac agtattctac tttaacaagc
    18061 gcttcaccat gaccaatatt tggaagatca tgctcaacaa cttcgacacc tgtactagct
    18121 tgattaacaa ctacggcttt catatcagtc ctccatctaa taatgacttt tttgtaatcg
    18181 attacaaata aattgtacat cttttcacaa tgaaagtcaa tagaaacctg aaaagtttct
    18241 gaaacttaac tggttaatct tatagctgtt tgcctatctg caaaatactt aactacattt
    18301 tctgacactg gatataaatg atatatttag aaaataaaat gatttcttat gactttaatc
    18361 ataagaaatc atttcctggt atcaacatta aaaatcactt acgtcgtcct ggacgttcag
    18421 cataaccata gtaagcatct tcaataattt cttgcatgtg atcaaccatt ggaagacgtg
    18481 ggttagcagg tgaacattgg tcttcataag caaggtaagc caattcacga gaatgttctt
    18541 tccattcgtt ttcgtcgata ccttgagctt tgaagttcat ttgaatacca actcggcaac
    18601 ccagatcata aacagctttc gcataagatt ccactgcttc ttctggtgta gaagctggaa
    18661 gccctaacaa tttcgcaatg tcttggtatt tttcatccgc acggtagtaa ttatacttag
    18721 gccatgtcgc cgttttagct ggacgagtcc cattatagcg gataacatac ggcaaaagaa
    18781 ttgcatttgt acgtccgtgt acggtatgga attgtgcgcc aattttatgc gccattgagt
    18841 gagaaatacc taagaatgca ttggcgaaag ccatacctgc catagttgac gcattatgca
    18901 tcttttcacg tgcttcaaaa tcggctgttt taactgattt ttcaagatta tcaaaaacaa
    18961 ttttaatggc ttgaagagct aaaccatccg taaagtcatt ggccatttgt gacacgtaag
    19021 cttcggttgc gtgtgtcaaa acgtccatac cagtatcagc agcaataaag cctggaacag
    19081 tcaataccaa agctgggtca acaatggcta cagttggtgt taatgagtaa tcagcgattg
    19141 gatatttacg attatttgct ttgtcagaga taacggcaaa tggtgtcacc tctgaacctg
    19201 ttccagaagt tgttgggata gcaacaaatt ttgttttctt accaagttct gggaatttga
    19261 acgcacgttt gcggatatcc atgaattttt gaacgaggtc atggaaatca acttctggtt
    19321 gctcgtagaa gagccacata actttggctg catccatagg ggatcccccg ccaagggcaa
    19381 taatggtgtc tggtttgaag gtacgcatta attcagtacc tttcataaca gttgtaatgt
    19441 ctggatctgg ttctacttca gcaaagatct gataaacaac tttattgcga cgaagatcaa
    19501 gttgttcaat gatacgatcc aagaaaccaa gctcaaccat agcgtgatct gtaacaatca
    19561 tgacacgttc aacgtcacga catttttgca aatattgaat tgaatcacgt tcgaagtatg
    19621 tttttgaagg aactttaaac cattgcatat tatttctacg tcttcctact tttttgatgt
    19681 tcaagagatt tatagcacta acgttatcac caactgcgtt acgtccatac gaaccacaac
    19741 caagagtcaa tgatggtaag aaagcattgt aaacatcccc gataccacca aatgtagaag
    19801 gtgaattcca gatgacgcgg atagcacgga ttctagttcc aaattctttt gccaattctg
    19861 catctgctgt atgaatggca gctgagtgac cgagtccatt aaattcaacc atttgacgag
    19921 ctttttcaac accgtcttca cgtgattcag attttaaaac agcaatgact ggagataatt
    19981 tttcacgtgt taaaggctca ttttctgaaa cttctttaca ttctgcagca agaatattgg
    20041 ttccttctgg aacagtaaat ccagcttgtt ctgcaatcca agtagctggt tttcctacaa
    20101 tatttggatt taattttgca ccagcacagt ttttgctatt tgctttggca ccaaaacaga
    20161 attcttcaag aagggctttt tcttttttat ttacaaaata agtatggtaa gatttgaatt
    20221 ctgctacaaa atcgtcatag atttctttat cgatgataac agcttgttca gaggcacaga
    20281 ccataccatt atcaaatgat ttagacatca caatatcatg agcggcttga cggatattag
    20341 ctgatttttc aacataagct ggaacgttac cagcacctac cccaagggca ggtttcccac
    20401 atgagtatgc cgctttaacc atcgcatttc cacctgtcgc aaggatagtg gcaatgccgt
    20461 catgattcat caaagcattt gttgcttcaa gtgatggtgt ttcaacccac tgcacacaat
    20521 tttcaggagc accagcggca atagcagcat cacgaacaat acgagcggca tgtgctgatg
    20581 attcttgtgc tgatgggtga aaggcaaaaa taattggatt acgtgttttt aacgaaatca
    20641 aagatttaaa gatagctgtt gaagttgggt tagttgttgg tgtaatccca cagataacac
    20701 ccaccggctc agcaattaat gtcaaacctg tcacatcatc ttcttcaata attcctactg
    20761 ttttttgatg gcgcatgtta ttaaccacat gctcacaagc aaatagattt tttgttgctt
    20821 tatcttcaaa gacaccgcga cctgtttctt cataagcatg tttagcaagt tcaccgtgag
    20881 catccaaagc agcaacagaa gctttggcta cgatataatc aacttgttct tggtcaagct
    20941 tacgcatctc ttcaagagca gctaaacctt tttgaacaag agcatcaatt gtcacagaaa
    21001 cagaggttgt ttcaacagta ttatgtcctt cagtcatttg agactccttt atattgttaa
    21061 aagtttcaca attttgttta caaaattatt atagcacttt ttgaaatttt gtaaatcatt
    21121 tcacaataaa tttgtgaagt ttttttcaaa ttatttctga aatcctatgg tatcaatatt
    21181 cttcattaac tttttttcag aaatatatct aaaaaaagcc gttttatttc tgaaaccgct
    21241 ttcttttaaa aacctcaaag tactactatt ttaccatcat catttgttca caagaaaaag
    21301 ccagagcaca atggatctga cttatctctt agacattttt taactttatt tagctggttt
    21361 tttagctgac ttctcaacag cagtctggat tgtggagaca tatagttctg ctccttgact
    21421 atcttcacta taatgaacac catcactgcc ataccaaata tctggatgtt caacagcaac
    21481 tttataccag tctgcaatag tgacatactt gtattttttg gacaatttaa gaccatagtc
    21541 tctagcttct gcaacctgac tggcattttt ggcattatat ggagaaacca aaactaaacg
    21601 atgacctttt ggcaatgcct caataaaaga ctgaactgct tgagaatagt tgtcaagcga
    21661 gttaacacct actgctaaga caacagtctt agatagactc ttagatttaa tttggttatt
    21721 aaataaatcg aaagcttctt taaaattccg actgaccgct gcatccagtt gcgcttgtgg
    21781 cataatttgt gagaatgctg cactagagcg taatgctaca gaatcaccaa taatacctac
    21841 gtcactcaaa gcattagcgt ctcctgcagc tagtgtatgt gtccgctcca tattactttg
    21901 agcctgttgt agggaactga ccaacaattg tttctcaaac ttaccaactt taggcgctat
    21961 catacaagtt cctaaagtta ataatgctaa ggcgagagac cctcctacaa tccacttata
    22021 gtaaggagaa cagtcaattt ctaaaccaag caggtttggt tttctccctt ggaccaaagg
    22081 ttccacaata tagtaagaca cagtggcaaa caagattgaa aagaaaactg ttagaataac
    22141 tgccaaaata tgagacatta attggctaaa aataatgtaa aatggccaat ggaagaggta
    22201 aatcccatag ctaatatcag ctatataagt gatagcttta ggctcttgta catctggtgt
    22261 ttgctcatga agaacacgcg ctgcataaat cataattgat gcgaataagc tagccaaagc
    22321 aaagccaaat agataggtcg tgatatggtt aaaatccaat gtgaccgtta gcacaagcaa
    22381 aagtgtaaat gctccaatca tagcagcaag gacatactgg cgcggccata aacgtacatt
    22441 tttttgaaat cgaacagtag tctcgttaat acctgttatc gtggcaaaca tcgcccctaa
    22501 aaagaaggga aaactgtgag aaagactcga aaaataaatc agggaaaaat ttgaggtcat
    22561 aaaagatctt ataaacatgc tcaagaaact aatagcaaat attcccaaag aaatcaaaaa
    22621 cagtagtcct ctcagttgtt tctgagtctc cttgcgtcta gctaataacc aaacaaatac
    22681 accccaaaac aagtaaaaat gaacttcaat agctaagctc cacgtatgaa caaagagatg
    22741 tggaataaat tggctttcat aactacttcc cgtcaatatt tcataaatat tagtggtaaa
    22801 tcctaaaaca gctgtaatct gacttcctat attagcaatg aaatccttct taattaaaaa
    22861 cgtaaaagga atggtcaata aaatcattaa caccaaagga ggaacaattc gataaaagcg
    22921 tctttttaaa aaaccgataa tatcgataga ctcttttttt gtgtattcat caatcaagag
    22981 ggctgtgatt agatatcctg aaaaggtgaa gaaaatgtca acaccaataa aacctcctgg
    23041 aaatacattt ttaaaaaagt ggtagagtaa aaccagtaaa agtcctgtta ccctaacaaa
    23101 cgaaaaccat tttattctca tttttgaaat atcccctgtt taaaaatccc tttatagact
    23161 ttattattct ttgcttttaa cacacctttg ccatttgctt gtcctttatg aaactccccg
    23221 ttatataacc agcccgtctt agcagtaaaa gttccttttc cttcaaatag gccatcctta
    23281 aaagtaccct catagatatc accgttgggg tagacaagct tcccttctcc attcatttta
    23341 tggttaatca cgtaaccagt atagtgcata cgccctttat cataggtcaa acttgtctta
    23401 ttcgaaattc ttacgctaaa aacagaaatt gcacaaacca atatgacaat caccgagaca
    23461 atttccaact tcgcccgtgt aatactccat ttttttacta tatcttgcat atctatcatt
    23521 tcttttactc aacttctaat atcaatactc tttactcatt aaacgagaaa gccaatcctg
    23581 gcatcctttt ctaactaatt ggtaggtttc ttcaaaatcg ttagtgtacc aaggatcagg
    23641 aacaccccct tctctaaaca ggtagatttt agagtcccat tgatgttgcg acatctcttt
    23701 gagatttttc acattatcgc tatccatacc aataatatag tcaaaggtgt taaaatcagt
    23761 tatagttatc tgcttggagc atttagttat atcataatta atttggtaag tttttaatat
    23821 ggactgtgta cctgagtgaa tagggtttcc atgctcccaa tcagaagtag cacgactttc
    23881 tatcatcata acatcacttg atactattga cttcattaca aactcagcca tggggcttcg
    23941 acaaatatta cccagacaga caaaacatac ttttttcatt aaatactcct ttgaattatt
    24001 atatcaaatt tctaactgat atcggagaaa tcaatctaat aattttctgt caacttatca
    24061 aaaaatccga acacaaaaag caggttcaga ttaattttct tagatttgaa aaatcattaa
    24121 gtgttttgat agggatagcc aagatgacga taagcctttt gcgtcgctac acgacctgtt
    24181 cgtgttcgca tgagaaagcc tttttgaatt aagtagggtt catacatctc ttcaactgta
    24241 ttacgctcct cggcaatatt cacagataat gtccccaaac caactggccc tccctgatac
    24301 atctcaatca tcgttcgtaa aattttctga tcaatgtaat cgagaccttc gcggtcaaca
    24361 tctaacatag tcaaagctct atcagttatt tgagccgtta tgatgccatc accaataatt
    24421 tgagcatagt cacgcactcg ttttagtaat cgattagcaa tgcggggcgt tcctctactg
    24481 cgacaagcta atttccgtgc agcttcatgg tctattttta tttcaaaaat agtagctgta
    24541 cgctccacaa tctctgtcaa atccttttct tgatagtatt ccatgtgacc agtgatacca
    24601 aaacgagctc tgaggggatt agataacatg cctgcacgtg tagtagcacc aatcaatgta
    24661 aatggaggca gatccaaatg aatactacga ctagtatctc cagcgccaat cataatatca
    24721 atatagaagt cttccatagc actatatagt acttcctcga cagacattgg catgcggtga
    24781 atttcatcaa taaacaaaat atcccctggt tctaattcat ttaaaatagc taccaaatct
    24841 ccagctttct caacggcagg acctgaagtt tgctttaaat taactcccaa ttcattggca
    24901 atcacaaatg ccattgttgt ttttcccagt cctggaggtc caaataataa aacatggtct
    24961 aaagattcgt cacgtctttt agctgcttct ataaaaatag cgaattgttc cttaacttta
    25021 tcttgtccaa tatattcgtg tagatattga gggcgaagag tccgatccga aaactcctca
    25081 tttcccatta cattattgtc taaaattcta gccataagac tattataaca taaagtaaaa
    25141 gagagcagtg gcctactttt attataatcg ccaccagtca acagcactaa gctcttgaac
    25201 tactttaaaa gatagtagag ctgcgaa
//
LOCUS       DAUGJR010000026        25201 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUGJR010000026 DAUGJR010000000
VERSION     DAUGJR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25201
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.026"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            77..1738
                     /locus_tag="VH800_001125"
     CDS             77..1738
                     /locus_tag="VH800_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8362200.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIIYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            1871..2656
                     /locus_tag="VH800_001126"
     CDS             1871..2656
                     /locus_tag="VH800_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEQ8362201.1"
                     /translation="MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGK
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            2686..3012
                     /locus_tag="VH800_001127"
     CDS             2686..3012
                     /locus_tag="VH800_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362202.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            3058..4965
                     /locus_tag="VH800_001128"
     CDS             3058..4965
                     /locus_tag="VH800_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8362203.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQVLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPNGLDRYSGNYSRFMALKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTGGRKSAHMTFHAEKPSGNVVLRVEEAAI
                     GYGDQVLSEPINVDINKLDAIAVVGPNGIGKSTLIKSIIGQLPLLKGQLKYGANVETG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQEALME
                     EWETIAEQIES"
     gene            5250..6218
                     /locus_tag="VH800_001129"
     CDS             5250..6218
                     /locus_tag="VH800_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEQ8362204.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGVPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            6277..7275
                     /locus_tag="VH800_001130"
     CDS             6277..7275
                     /locus_tag="VH800_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEQ8362205.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            7460..8869
                     /locus_tag="VH800_001131"
     CDS             7460..8869
                     /locus_tag="VH800_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEQ8362206.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPAVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGANKMCLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVSRPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            9196..10959
                     /gene="lpdA"
                     /locus_tag="VH800_001132"
     CDS             9196..10959
                     /gene="lpdA"
                     /locus_tag="VH800_001132"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEQ8362207.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVS
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAM
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            11269..11406
                     /locus_tag="VH800_001133"
                     /pseudo
     CDS             11269..11406
                     /locus_tag="VH800_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(11633..14050)
                     /gene="hylA"
                     /locus_tag="VH800_001134"
     CDS             complement(11633..14050)
                     /gene="hylA"
                     /locus_tag="VH800_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEQ8362208.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASANITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIKADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTSVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTG
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKYPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWKNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYGKKATMFSNHNLSHQGFYSFPH
                     PVRQNQQ"
     gene            14283..15272
                     /locus_tag="VH800_001135"
     CDS             14283..15272
                     /locus_tag="VH800_001135"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8362209.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILAKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            complement(15381..16172)
                     /locus_tag="VH800_001136"
     CDS             complement(15381..16172)
                     /locus_tag="VH800_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEQ8362210.1"
                     /translation="MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(16172..17515)
                     /locus_tag="VH800_001137"
     CDS             complement(16172..17515)
                     /locus_tag="VH800_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEQ8362211.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     ERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFVCLNCQFQRPTLDYQLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTVGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI"
     gene            17622..18473
                     /locus_tag="VH800_001138"
     CDS             17622..18473
                     /locus_tag="VH800_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEQ8362212.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSNSNVTLPWYKK
                     ILGGKSK"
     gene            18470..19426
                     /locus_tag="VH800_001139"
     CDS             18470..19426
                     /locus_tag="VH800_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEQ8362213.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            19480..20835
                     /locus_tag="VH800_001140"
     CDS             19480..20835
                     /locus_tag="VH800_001140"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEQ8362214.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     TRPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            20969..21610
                     /locus_tag="VH800_001141"
     CDS             20969..21610
                     /locus_tag="VH800_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362215.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQMLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            21673..22803
                     /locus_tag="VH800_001142"
     CDS             21673..22803
                     /locus_tag="VH800_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEQ8362216.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            22813..23565
                     /locus_tag="VH800_001143"
     CDS             22813..23565
                     /locus_tag="VH800_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEQ8362217.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            23565..24329
                     /locus_tag="VH800_001144"
     CDS             23565..24329
                     /locus_tag="VH800_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEQ8362218.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHIETSIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            24329..24961
                     /locus_tag="VH800_001145"
     CDS             24329..24961
                     /locus_tag="VH800_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEQ8362219.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDSVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
BASE COUNT         7825 a         4425 c         5322 g         7629 t
ORIGIN      
        1 tagcatagct acataacagt aattcgactt acgttgtaag gaccgtttgt aataataaaa
       61 tatttaaagg agtatcatga ctgatattaa aatgattgcc ttgggagggg tccgtgaata
      121 cggaaaaaac ttctatttgg tagaaattaa cgattctatg tttattttag acgcagggct
      181 caagtaccct gaaaatgagc aacttggggt agatttagtc atccccaatt tagattatgt
      241 aattgaaaac aaaggtaaag tacaagggat tttcttgagt catggccatg ctgacgccat
      301 tggagccctt ccttatttgt tagctgaagt atcagctcct gtatttggat ctgaattgac
      361 tattgaatta gccaagctat ttgtgaaaag taataacagc actaagaaat ttaataattt
      421 tcatgtggta gacagtgata ctgaaattga atttaaagat ggcctagttt cgttctttag
      481 aacaacgcat tcaatcccag aaagtatggg tattgttatt ggaacagata aaggaaacat
      541 tatttatacc ggtgacttca aatttgatca agcagcaaga gaaggttatc agacggattt
      601 gctacgttta gctgagattg ggaaagaagg ggttctagct cttttatcag attcagtcaa
      661 tgcgacaagc aacgatcaga ttgccagcga atctgaagtt ggtgaagaaa tggacagtgt
      721 tatctctgat gctgatggcc gtgtcattgt agctgcagta gcctcaaatc ttgttcggat
      781 tcagcaagta tttgattccg ccactgccca tgggcgtcgt gttgttttaa ccggaacaga
      841 tgcagaaaat attgtcagaa cagctttacg tctagaaaaa ttaatgatta cggatgagcg
      901 tcttttaatt aaacctaagg atatgtctaa attcgaagac catgaattaa tcatccttga
      961 agctggtcgt atgggtgagc caattaatag cttacaaaaa atggcagcgg gacgtcaccg
     1021 ttatgttcaa atcaaagaag gagaccttgt ttatattgta acaacaccaa gtacggctaa
     1081 agaagctatg gtggcgcgtg ttgaaaactt gatttacaag gccggtggtt ctgttaaatt
     1141 aatcactcaa aacttacgtg tttcaggcca tgctaatggg cgtgatttgc aactattgat
     1201 gaatttgtta aaaccccagt atctttttcc agtacaagga gaatatcgtg atttagctgc
     1261 ccatgcaaag ctagctgaag aagttggtat ttttccagag aatattcata ttctgaagcg
     1321 tggcgatatc atggtgctta atgacgaagg ttttctccat gaaggaggtg tacctgccag
     1381 tgatgtcatg attgacggta atgctatcgg tgatgtgggt aatatcgttt tacgagaccg
     1441 taaagtcttg tcagaagatg gtattttcat tgttgctatt actgtttcta aaaaagaaaa
     1501 acgcattatt tctaaggcta aagttaatac gcgtggattt gtgtatgtca agaaaagtca
     1561 tgatatttta agagaaagtg cagaattagt taatacaact gttggcaatt acttaaaaaa
     1621 agataccttt gactggggcg aattaaaagg gaatgtcaga gatgatttgt ctaaattctt
     1681 atttgaacaa accaaaaggc gcccagcgat tctgccggtt gtgatggaag ttcgttagtg
     1741 aaaataggaa ggttaggcaa aaactgccta ccttctttga ttttaacaac tggtaaacca
     1801 ggaaactgtt cacccaaaaa tacagtagat ttacgtgata ggattatttt ggtataaagg
     1861 agtgtaatga atggcaagta ttgcaattga ataccattcg gtagttttag gaatggagcg
     1921 taaggtaaat gtgatttatc ctgaccagtc tgaaatccct aaaaaagatc aaggggataa
     1981 ggatattcct gttttatatt tgttacatgg tatgggaggc aatgaaaact cttggcaaaa
     2041 acgaacagct attgaacgct tgttgcggca taccaatttg atagtcgtta tgccttcgac
     2101 agacctaggt tggtatacag acacggctta tggacttaac tattatcggg cgttgtcaca
     2161 agagttaccg caggtcttag cagctttctt tcctaatatg acccagaaac gagaaaaaac
     2221 ctttgttgct gggctctcta tgggtggcta tggtgccttt aagtgggcac tcaaaagcaa
     2281 tcggttttct tatgcggcat cgttttcagg cgctttggat ttttctcctg agaccttgct
     2341 tgagggaaaa ctgggagaat tagcctattg gcagggcgtt tttggccagt ttgatgaccc
     2401 tgaccttgac aagcattacc ttaaaaatat ggtggcagaa agtgatggaa aaaccaaatt
     2461 ttatgcttgg tgtggctatg aggattttct ttttgccact aatgaaaaag ctattgctga
     2521 ttttcaggct caaggtcttg acattgatta tcataaaggt catggtaaac atgagtggta
     2581 ctattggaac cagcaattag aagtcctgtt agagtggtta ccgataaact accaaaaaga
     2641 agaaaggttg tcttaaccat ttcctagtac aacatgaggt gacaaatgaa acaattactg
     2701 gcgatcattt tgtggctgcc taagctaata gtgaaaatgt tttggcacct tatcaaaggg
     2761 tttttacaaa ctatcttatt agtaacgatt attattatag ggctgatgta ctattctaat
     2821 cacagtgatt ccgttttagc caataagatc tcgatagtta ctgagcaagt ggtgcaaatt
     2881 tttgatatct taacacaaaa gccatctgca aagacgcgtc atgggagtgg taatagtcat
     2941 tccactttcc ttgttagcgc taaagaaggt aatcaacgac ttaaaaagag ttcgatttct
     3001 tttggaaact aggctgaaaa tgtcctcaaa agggtatttt tttgttagaa tgaaagtatg
     3061 attattttac aaggaaacaa gttagaacgc tctttctcag gagatgttct ttttcaaaac
     3121 atatcactac aagttgatga acgtgaccgc attgccttgg ttggtcctaa tggagctggc
     3181 aagtcgactt tactaaaatt attggttggg gaagaaaccc caacgagcgg agaagttaat
     3241 actaaaaaag acctaacctt gtcttatctg gctcaaaata gccgttttga atcagatcaa
     3301 acaatatatg aggaaatgct caaggttttc gaagcattac gccaagatga aaagcgcctg
     3361 cgtcagatgg aaatggatat ggcaaccgtt tcaggtcaag ttttaacccg actgatgaca
     3421 gattatgatc tgcttacaga gcattttcgt cagcaaggcg gctttacgta tgaatctgac
     3481 atcaaagcca ttttaaatgg gtttaagttt gatgagagca tgtggcagat gactatcgct
     3541 gagctgtcag ggggtcaaaa tactcgtctg gccttggcta aaatgctttt agaaaagcca
     3601 gaactattgg tccttgatga gccaacaaac cacttagata ttgaaaccat tgcctggtta
     3661 gagaactact tggccaacta tcaaggagct ctaatcattg tgagtcacga ccgttatttt
     3721 ctggacaaag tggcgaccgt gactttagat ttgacgccta acggcttaga tcggtatagt
     3781 ggtaactatt ctcgttttat ggccttaaaa gctgaaaaac tagtagccga agaaaaacag
     3841 ttcgataaac aacaaaaaga aattgccaag ctagaagatt ttgttcaaaa aaacattgtc
     3901 agggcctcta ccacaaaaag ggctcaggct aggcgtaagc aattggaaaa aatagagcgt
     3961 ttggacaaac ccacaggtgg gcgtaaatct gctcatatga catttcatgc agaaaaacca
     4021 tcaggaaatg ttgtgctaag agttgaggaa gcagccatcg gttatggaga ccaagtcttg
     4081 tccgaaccta ttaatgtaga tatcaataag ttggatgcta ttgccgttgt agggccaaat
     4141 ggtattggta aatcaacctt gatcaagtcg attattggac aattgccttt gctcaaagga
     4201 caactcaagt atggtgccaa tgtcgaaaca ggttattatg accaaaccca atcacatttg
     4261 acgtctagca acacagtttt ggaagaatta tggcaggatt tttcaactac gccagaagtc
     4321 gatatcagaa accgattagg ggcttttctc ttttctggag atgatgtcaa aaaatcggtg
     4381 gctatgctgt caggtggaga aaaagcccgt ctgcttcttg cgaagttatc tatggaaaac
     4441 aataattttc ttgttctgga cgagccgact aaccacctag acattgacag taaagaagtg
     4501 ctagagaatg ccctcattga ctttgacggt accttgcttt ttgtcagcca cgaccgctat
     4561 ttcattaatc gtttggcaac taaggttttg gaaattaccg aaaatggctc aaccctttac
     4621 ttaggtgact atgattatta ccttgagaaa aaggcagagc tagaagaatt agcccgccta
     4681 gcagcaggag agacagttga ggaaacaaaa gaagcctctg ccactgatta tcagctacaa
     4741 aaagctaatc aaaaagagcg tcgtcgcttg acccgccgat atgaggagat tgaagcaaga
     4801 cttgaaacca ttgaagagcg tattggtgct attcaagaag acatgcatgc ctccaatgat
     4861 acggcgcagt taatcgcttg gcaaaaggaa tgggaccaat tggatcaaga acaagaagct
     4921 cttatggaag aatgggaaac catcgctgaa caaatagaat cataaaaata agctttagca
     4981 gttttgctaa gcttattttt atcgctttgc tacttgtttg aaggtgtgaa agaggtttta
     5041 aaatgatgtg ttttttatgt caaggtcggt aaaacgtgaa actgttatat agtattttta
     5101 aattttttag tacagttttg tttgtaattt cacaaactat tgcatttcta aaaaaccaaa
     5161 taaggtaagg tagaaagcga tttaattatt tgcaaattgt gaaaaaaagt tttatcataa
     5221 aaaggtaata tgataatatg gaggccgaaa tggtaacagt ttctaaagaa caacatttag
     5281 atatgttcct taaaatggaa cgtattcgtg aatttgattc acgtattaat aaactcgtcc
     5341 gtcgtggatt tgtacaaggg atgactcact tctcagttgg tgaagaagca gccaatgttg
     5401 gagcggtggc tcacttgtct tacgatgaca ttattttttc aaatcaccgt ggacatggac
     5461 aatcaatcgc taaagacatg gaccttaata aaatgatggc tgagcttgct ggtaaagcaa
     5521 ctggtgtgtc taaagggcgt ggtggctcaa tgcacttggc tgattttgaa aaaggaaact
     5581 atggtactaa tggtatcgtt ggtggtggtt acgctcttgc agttggtgct gccctcactc
     5641 aacaatacaa aggaactaac aatatagctg ttgctttctc aggtgatggc gctactaacg
     5701 aaggatcatt ccacgagtct gttaatatgg ctgcaacatg gaaacttcct gttattttct
     5761 tcatcatcaa caaccgttat ggaatttcaa tgagcatcaa taatgcaaca aatacaccac
     5821 acttatacac acgtgcagaa gcttacggag ttcctggttt ctactgtgaa gatggcaatg
     5881 acgtgatggc tgtctatgaa acaatgggca aagccgttga acatgttcgt ggtggaaatg
     5941 gtccagctat tgttgaggta gaatcatacc gttggtttgg tcactcgact gcagatgctg
     6001 gtaaataccg tactaaagaa gaagtggatg agtggaaaga aaaagatcca atgatcaaat
     6061 atcgtactta tctgacaagc gaaggcattg ccactgatga cgaattggat gctattcaag
     6121 cacaagtcaa aaaagaagtt gacgatgctt atgaatttgc acaaaacagt ccagatccag
     6181 aactttcagt agccttcgaa gacgtttggg ttgactaaga gcaccttgtc agtaagaagc
     6241 aatcgtattt gaataataaa tggagaaata aaaatgatgt cagaaacaaa attaatggct
     6301 ttgcgtgaag cagtcaacct tgctatgact gaggaaatgc gcaaggacga aaacattttc
     6361 cttatgggag aagacgtagg ggtttacgga ggagactttg ggacttctgt tggaatgatt
     6421 gaagaatttg gccctaaacg tgttaaagat accccaattt cagaagctgc tatctctggt
     6481 gcggctattg gtgcagctat tacaggacta cgtccaattg tcgacgttac cttcatggat
     6541 ttccttacca tcatgatgga cgctatcgtg aataatggtg ctaaaaataa ttacatgttc
     6601 ggtggaggcc ttattacccc tgtaaccttc cgtgtggcat caggttctgg tattggttcc
     6661 gctgcgcaac actcacaatc tcttgaggca tggttgactc acattccagg aatcaaagtt
     6721 gttgctcctg gtaatgccaa cgatgctaaa ggcttattaa aatcagctat ccgtgataat
     6781 aacattgttc ttttcatgga accaaaagcg ctttatggta aaaaagaaga agttaaccaa
     6841 gatcctgact tctatatccc acttggcaaa ggtgacatca aacgtgaagg aactgatttg
     6901 acaattgtgt catacggtcg tatgttggag cgtgttcttc aagcggctga agaagtagca
     6961 gcggatggta ttaacgttga agttgttgac ccacgtaccc tcatcccact tgataaagag
     7021 ttgattattg aatctgttaa gaaaacaggt aaattgatgc ttgtcaacga tgcctacaag
     7081 accggtggat tcattgggga aattgcaacc atgattaccg aaagtgaagc ctttgattac
     7141 cttgatcatc caatcgttcg tcttgcaagt gaagatgttc cagtacctta tgctcgtgta
     7201 cttgaacaag caatcttacc agatgttgag aaaatcaaag ctgctattgt gaaaatggca
     7261 aacaaaggca actagaagat aaggcaagtg gtccgataaa ggctatgttt atcagtaacg
     7321 tctcagctaa aaactatttt gaaagttttt agaagaactg agttgtctta tcccgtgtcg
     7381 cggcacctca cctttcgtat gttttcgtag caaggtgagg atgttgatgg cgcttatcaa
     7441 atcgtgaaag gatgtagaaa tggcatttga aattattatg ccaaagctgg gcgttgacat
     7501 gcaagaaggc gagatcatcg agtggaaaaa acaagaaggt gataccgtca atgaaggtga
     7561 tatccttctt gaaatcatgt cagacaaaac caatatggaa cttgaggcag aagactcagg
     7621 tgttcttctt aaaattacac gtcaagcagg tgatactgta cctgtaactg aagttatcgg
     7681 ttacattggt gcagagggtg aatcagtaga tactattgct tcaagtgaaa aaacaacaga
     7741 aattccagtt cctgcttcag cagacgctgg accagcagtt gctccaaaag aaaatgtggc
     7801 aagtccagct cctcaagtgg cagcgacagc tattccgcaa ggaaatggcg gaaaagttcg
     7861 tgctactcca gctgcacgta aggcagcagc agaaatgggc attgaccttg gccaagttcc
     7921 aggaacagga ccaaaaggac gtgtccataa agaagacgtt gaaaacttta aaggtgctca
     7981 accgaaagct tcaccacttg ctcgtaaaat tgcagcagac aaaggtattg atttggcaac
     8041 cgtatcaggt actggcttta acggtaaggt catgaaagaa gacatcatgg ctattcttga
     8101 agcggctaaa ccagctgaag caaaagcccc agcagctaaa gaagaaaaag ttgttgatct
     8161 tccagaaggt gtggaacaca agccaatgtc agctatgcgt aaggcaatct ctaaaggtat
     8221 gacaaactct taccttactg cccctacctt tacgcttaac tacgatattg acatgacaga
     8281 gatgattgcc cttcgtaaga agttaattga cccaatcatg gctaaaacag gccttaaagt
     8341 cagctttaca gacttgattg gtatggcagt ggttaaaacc ttgatgaaac ctgagcatga
     8401 gtacatgaat gcttccctca tcaatgatgc taatgatatt gaattgcacc gctttgtgaa
     8461 ccttggtatt gccgtaggtc ttgatgatgg tcttatcgtt cctgttatcc atggggctaa
     8521 caagatgtgc ttgtcagatt tcgtgcttgc ttcaaaagat gtgattaaaa aagcgcaaac
     8581 tggtaagttg aaagcagctg aaatgtctgg atcaaccttc tctatcacaa acttgggaat
     8641 gtttggtacg aagacattta acccaattat taaccaacca aactcagcaa ttcttggtgt
     8701 tggagcaact atcccaactc caacggttgt ggatggtgag attgtttccc gtccaattat
     8761 ggcaatgtgc ctaaccatcg accaccgttt agttgatggt atgaacggtg caaaattcat
     8821 ggttgatctc aagaaattga tggaaaatcc atttgaattg ttaatctgat caatcagttt
     8881 taaacaagaa aagcattcaa taataaaagg gattttgcta agtttagact tggtgccctt
     8941 ttctcaaaaa tatagaaagg atgtagaacg aggagctctc atgcaaatga gtgataagca
     9001 attgaatccg agcgaaaagc tcggataaaa atggtaagag ttggctaatc ttagcgtcgt
     9061 agacgtctga actttcctca gtttttgttt cggaaagtcc tagtcgtcct gacgtgggtg
     9121 cgtcaacgaa atcaaagatt tctgacttac cgcaaaaatt caatcgcttt ctccttgctc
     9181 ttggtatctt aaattatggc tgttgaaatt attatgccaa aactcggtgt tgacatgcaa
     9241 gaaggtgaaa tcatcgagtg gaaaaaacaa gaaggtgata ctgtcaatga aggcgatatt
     9301 cttcttgaaa tcatgtcaga taaaaccaat atggaacttg aggcagaaga ctcaggtgtt
     9361 cttcttaaaa ttacacgtca agcaggtgaa acagtacctg taacagaagt tatcggatat
     9421 atcggtgctg aaggtgaatc tgttgaggtt tctagcccag ctgcttcaga tgtgaatgtt
     9481 gctcgtacaa cagaagattt agaagctgct ggacttgaag tgccaaaagc accagctcaa
     9541 gctgcttcag ctgcaccaaa agctgcactt gctgatgatg agtatgacat catcgttgtt
     9601 ggtggtggcc ctgcaggtta ttatgcagct attcgtggtg ctcaacttgg tggtaaaatt
     9661 gccatcgttg agaaatctga atttggtgga acttgcttga acgtagggtg tatcccaacc
     9721 aaaacttacc ttaaaaatgc tgaaatcctt gatggtatta agattgcagc aggacgtggg
     9781 attaaccttg cctcaactaa ctatactatt gacatggaca aaacagttga ctttaaaaac
     9841 accgttgtta aaaccttaac aggcggcgtt caaggtcttc taaaagctaa taaagtcact
     9901 atctttaatg ggcttggtca agtcaaccct gacaagactg taaccattgg gtcacaaacc
     9961 attaagggtc gcaacgttat ccttgctaca ggttctaaag tatcacgtat caatatccca
    10021 ggtattgact ctaaacttgt cttaacgtca gatgatatcc ttgacctccg tgaaatgcca
    10081 aaatcactag cagttatggg cggtggtgtt gttggtatcg agcttggact tgtttgggca
    10141 tcttacggtg tggatgttac cgttattgaa atggctgacc gtattatccc agctatggat
    10201 aaagaagtct ctcttgaact tcaaaaaatc ctttctaaga aaggcatgaa gatcaaaaca
    10261 tctgttggtg tctctgaaat tgttgaagca aataaccaat tgactttgaa acttaacaat
    10321 ggtgaagaag ttgttgctga aaaagctctt ctttctatcg gacgtgtatc acaaatgaac
    10381 ggtctggaaa atcttaacct tgaaatggat cgtaaccgta tcaaagttaa tgactaccaa
    10441 gagacatcaa ttccaggtat ctatgcgcca ggtgacgtta acggaacgaa aatgcttgct
    10501 cacgctgctt accgtatggg tgaagtggct gcagaaaatg cgatgcatgg caacacaact
    10561 cgtaaagcta accttaaata cactccagca gctgtttaca cacaccctga agtggcaatg
    10621 gttggtttaa ctgaagaaca agcgcgtgaa caatatggtg atgtgcttat tggtaaaaac
    10681 agctttactg gtaatggacg cgcgattgct tcaaatgaag cacatggttt tgttaaagtt
    10741 attgctgatg ccaaatacca cgaaatctta ggtgttcata ttattggtcc agctgcagct
    10801 gagatgatta acgaagcagc tactattatg gaatctgaat taaccgttga tgaattgtta
    10861 ttatcaattc atggacaccc aaccttctct gaagtgatgt acgaagcctt tgcagatgtg
    10921 cttggcgaag ctatccataa cccaccaaaa cgtaagtaaa acgtctttgt cttattaact
    10981 aatgaaaaat atcatcacat aacagatcac aaaaaagact agcacaacta tgaactgcac
    11041 cccaaacgtt agatataaaa ccctaacgtt tggggtgttt ttgtatgaca ttaagctatg
    11101 aagataagct agacatttag cgctaaaaaa accgagagaa ctccgtttga aagaagcatc
    11161 tctgaaaaga agaagacaaa aaaccattat aaagaatgga taaagacgag ttctgattag
    11221 attttctttt aaggacggct aaattgactc gttctaccta ctattatcat cgattattgc
    11281 aacaataaac gtatcaaaat aaaacgaaaa ggacttagtc ctctacaata cagaactaaa
    11341 tcctttactt caaatagagt agccaacttt tggggctcag tgcagtttct agttttttgt
    11401 ctttaataac gtttcattgt taacccttac tttccaataa cagctaaatc cttaagtctt
    11461 tcttacgaaa gggttttgtg atatggttaa aagaagcaac taaagctcca cctaagaatt
    11521 ctaaagagga ggactgatac ccagtatgcg gtaagcgtcg ttgtcttttg tggggaattt
    11581 tatgagagtt aagagcattg tttttagctg caattccttg atcagcaagc ttttattgtt
    11641 gattttgcct gacaggatga ggaaaactat aaaagccttg atgagaaaga ttatgatttg
    11701 aaaacatcgt tgcttttttt ccatagtgaa tgacgtgcat ctgttgacta tcatgatcgt
    11761 agacagcggc cagtttgtca ttgttttcta ataagtcgat atcaagcttg ctaatatagg
    11821 tttcaaattc ttgacgagtc atatttggaa gcatcatata ggcataacga tcgccatctt
    11881 gagtatggtt ttgcatgata gtgataaagg tatttgaaac ttctttgatg gcttctggtg
    11941 atttgtcatc agcttttatg tttttccatt tccctgtttg aagtgcctta cttatgctaa
    12001 gtgttgttgg cttgaagaag tagtaaccaa tattttgagc gggatcatca ctttcaagga
    12061 aaatactttt agtgtttgta aaatcaacta gctgattatt caagtcaacg ggttgattgt
    12121 taacataaga acagtaaggg tacttttgat tttcttttcg ttgttcaata gttgtatacg
    12181 ccttgtgaga tgattggttt ttgatattgc taccaacaaa gattattttg tttcctaaga
    12241 taaaccaccc tttattgagg gtgaggcttt tattccaatt agtgaaggtc atagcagcta
    12301 gagcacttgt gttattaagt tttttacttg caacaaaagc gtcatcagag agaccagtca
    12361 tgccaacttg ttgatagttc gttttaatat tctcaggagt tccctctagt ggtttttgct
    12421 cagtttctgt ggttccaggt aagcggtagg gatttaccgt tgcccaatag ttttcactgt
    12481 agtgtcctaa atcgttattg tataggtaaa acattccatc agaagtaaac cagccatgaa
    12541 gattttcatt attcatagct tcataatttt gagttcgatt cgaaaacatt gataggccaa
    12601 aagcaaaatc gtgtttatta ttatatagtg ccaatttatc catactattg aaactagcta
    12661 cgtaactatc aagtttttgg actggaacag aagtatcact tagtagttct ttcataagtt
    12721 tgatatcgtg ataggttttc aaattatcat agacattgta aaaagcattc ccttgtgtga
    12781 cgagtgtttt tatacgtgtt ttaagtgcca aacggtgagg ctcttcagac atgtcagcaa
    12841 tacgtaaaat agcacgaagt gcttcaatgc cagcaacatg agattgggca ttaaaacgac
    12901 tgatagaacg ccctcgagtc atatccatca tttctccacg aacgatgata gggaaaaaag
    12961 aatggttaat ccaatgatag atagtagcca ttttatccgc ttttatagga gactttgttt
    13021 tttgaataat aggaattaat tgcgataagc catctataag cacattaccg taagctccag
    13081 tgtaagcaat gcctttttta taaagtggac tttgagcgtt agtaaccacg tgatcaatta
    13141 aagaaccgtc ttggtaaaaa ccatttcctt catcaactag cgtgaaaact ttctcaattg
    13201 ctttgattgt atcactaatt tcgagatcat ctttacgaag aataccggaa atgagtttaa
    13261 cacgccccat atcaattaaa tttccgctat tggcttcaaa aggtgaaaaa ttggcagcgc
    13321 gaaccctaaa acgagtaggg tcaggcacaa atttttcgat tggagctgtg tatttaagaa
    13381 tttcttcttg agtaaaataa ggatacatca aggataaggt attattaata gcacgaggag
    13441 ttccaatttc ataaacccac caattttctt tgttttcttt tccagttgtt tgatgatttt
    13501 cacgatctag attataagcg tgttcataca tgaaggccat accgtctttt acaatagcaa
    13561 tagctttact atcttgataa tagcatgatt caggattagt gatctgtttt gctatttttt
    13621 caatattgcg gtaagttttc gtgatattag cagaagcgga ataatccttt gcatgttccc
    13681 aaaggtaagt tctattttcg tggtcaggcc cttgatagct tttaataatg ttttgagcat
    13741 ccttttcagc tttattatga aaagtgacca tgtcaggatt ggttttatca taagcatcgt
    13801 tgcctgcgat aatactgttc cattggtcta acaattcagt atagtagtct ttttgttgtg
    13861 gctgtactac ctttttttcg ctatctgtag tagtgagcgt ttgcgtttga aagtaagtat
    13921 tattaggttc tgaatttgaa gtcagtgtat cggcataaat ggcagttcct tggcccatca
    13981 tagcaaagct aaggaatagg tttgaataaa gtagtaattg tttatggtgt gtgcaaaaat
    14041 aagtattcac tgataaattc ctccaatata aaaatgagat aataaaagta aattgattta
    14101 ctaagtaaaa atataccacg ttaaagtatt tttataaacc cttacataaa taatggctga
    14161 gtttttgtgc actaataagt gtaggtactg aagatgtcat acagaatagg acacttgtct
    14221 tttatatttg ttttcattat actagagagg tagattacat ttttgaaagg attttttctc
    14281 ctatgaaata catcgttaac aaaagtcaca atcctgcctt taacatcgct ttggaagcct
    14341 atgcttttag agaactagtg gaagaagacg aattgtttat cctttggatc aatgagccag
    14401 ctattattat tggcaaacat caaaatacca ttcaagaaat caataaagaa tacattgatg
    14461 aacatggtat tcatgttgtg cgacgtttat ctggtggtgg tgcggtttat catgatttga
    14521 ataacttgaa ctacactatc atttcaaata aaacagcgga aggcgcattt gatttcaaaa
    14581 ccttctcaca acctgtgatt gcgactttag ctgatttggg tgtaacagcc aactttacag
    14641 gccgtaatga tattgaaatt gatggtaaaa aaatctgcgg taatgctcaa gcttactaca
    14701 aaggtcgcat gatgcaccat ggttgccttt tgtttgatgt ggatatgacc gttcttggcg
    14761 atgctcttaa ggtaagtaag gacaagattg agtctaaagg agtgaagtct gttcgtgctc
    14821 gcgtgaccaa tattttaaat gaattaccag aaaaaattac cgttgaggaa ttttcagata
    14881 aaatcttggc caagatgaaa gaaacgtacc cagacatgac agaatatgtc ttgtcagagg
    14941 atgagttggc taagattgaa caatctgcca aagagcaatt tggtagctgg gattggacct
    15001 acggcaaagc gccagaatat acgattgaac gcaatgttcg ttaccctgca ggtaaaattt
    15061 caacctttgc aaatgttgaa aattctatca ttaaaaacct taaaatctat ggtgatttct
    15121 ttggaatcaa agatgtgcaa gacattgaga acttattaat tggttgtaaa tatgagtacc
    15181 gtgatgtttt tgaacgttta aaaacgattg atacgaccca gtacttctca cgcatgaccg
    15241 ttgaagaagt tgctaaagct attgtttctt agtggtttta atcacttaag aagctctgtc
    15301 agaagaaaaa actataaaac tcctaagcga actatcgtgt cctacttagg agtttttgtt
    15361 tgatgacatg aaagaagaac ttaaacttta ttaaaggaag ctttgctttt aaggtcggca
    15421 tattcttcag tgatttcttg tttcagtata tcatcatagc taggtagtga aatagctgat
    15481 ccatactttt ttttaagagc tgttgttact aagcggtaag caagattaac attgcgtgat
    15541 aagataggac cgtggaaata actaccatag acgtttttat agtgaacacc ttcagtttgg
    15601 tcttctttat tattaccgtt gccataaacc actcgtccaa gtggcttttc gtcaccagat
    15661 aagaaggtac gtccttgatg attttcaaag ccataatagg tttcgttaaa ttcgtcatta
    15721 tgaattttaa tatctccaat aaagcgattt tggtgctgat taagggtgta gtgtcccata
    15781 attccaagtc catcaatttt aaccccatta gcttggacat agtattgccc tagtaattgg
    15841 aagccaccac agatggcaag caccacttta ttattagcaa tgtaatccgc taaggcagct
    15901 tttttgctag gcaaatcctt ggcaacaatg ctttgttcat aatcttgacc accaccaaag
    15961 aaaacaatat cgtaatcgtc ttgttcaaag gtatcattga tagacacaat atcaacagtg
    16021 accctagctc caagtttttc agcgacatac ttgagcatta aaatattgcc gttatcacca
    16081 taagtattca taagattacc atagagatgg gcgatagtga ggtcgtagat gtaatcttga
    16141 ttttcgggag attttagtga agtgtatgtc attagatcat ctccttttca acgacatggc
    16201 ggtcagcaag taagctacgg aattctaaca ttgccgtata ggttgctaaa atataggcat
    16261 gcttagcttc ttgtttttca atggtttcta tgatttgctc gagcttttca gcttgtttta
    16321 tcttagtatc gtcaaatcct gtgactctaa gtcttctagc aatttcagag tggcggacgc
    16381 cgccagcatt aatttctgta atgggcattt gggtaatgag ttcaaaatta gcatcccaaa
    16441 tccagctggt atcaatgcca tcagcgtaat tggcatttaa taaaactgat aagctaaatg
    16501 gataatctgc caattgaatc atttccagtg cctgactggc tccaacagga ttcttgataa
    16561 ggataagggt gcatgattta tcaccaacag taaaagtttc ttgtcttcca aaaaccgcct
    16621 tacttttgtt aaagcccgcc ttgattttct cgggagaaac accgaaaaat tcagcaacag
    16681 agacggcagc gagcgcattg taaatattat aaagaccacc aacatttatc ttgtagtttt
    16741 gtccatcaat aacaaattca gaactttggt gagtaatagc ggtgagctca gttaattgat
    16801 aatctaacgt tggtctttgg aactgacagt ttaagcaaac aaagtctcct agattcgcat
    16861 aagtattgag acgatactga agaatatgtt cgcattttgg acataaaatc ccttctgtgt
    16921 tgtaatgagc tagctgcgga gcatgcttag cagtatcaaa accataatac tgaactggat
    16981 taactatgtc cttagaagag aaaataggac tatctccatt ggctagaata gttgcttttg
    17041 gagcatttcg agcaccatct acaatcatct gataagtagt gtaaatctct ccgtagcggt
    17101 ccatctgatc cctaaaaata ttagtataaa caaaaagact aggttttaag taagtggtaa
    17161 ttctaggaag actagcctcg tcaatttcta aaacagcaat ttgcctttca gatttccctt
    17221 ttttagcagc taaaaaagta gaagtaattc cagtaatcat attggcacca cttggatttg
    17281 tgattatctc gccaaatgcc tctttcaaaa taccgacagt aagagcagtt gttaacgttt
    17341 taccattagt accagtgacg accacaatat catagtcttt agacaaatcc tttaaaatat
    17401 ctttatcaca agctagagcc aatcgaccag gataagtaga tcctcgccct agttttgtta
    17461 aaatggattg agcagctttg ccagcaataa tgccgagtaa tgtcttcatt ttcatgctta
    17521 tattttatca taagtttatt gattttagat agggaaaaat ctttgatcat gatatgatat
    17581 aatatagcta ataacttttt tgatatagaa atgagagttg tatgaataat ttatctagta
    17641 tcgatattaa atttttatta agcttatttg cggatccttg gctgctggca gtgcatcttt
    17701 tagatattct aattgttgcc tatttgattt atcgttttat taaagcattg actggaacta
    17761 aaatcatgtc tttagttcaa ggggtcattt tctttttggt tcttcgtttt attgcagagt
    17821 ggattggctt tacgacaatc acatacttaa tgaaccaagt cattacttat ggtgtaattg
    17881 caggagtagt catttttacc cctgaaattc gggcaggact ggagaaattt ggtcgttcta
    17941 cgcaagtttt tttacaaaaa cagtacgtca gcagtgaatc tgctttggtc gatgctttga
    18001 ttaaatctgt ggcctatatg ggtccacgca agataggtgc attgattgct attgaacaga
    18061 ctcaaacctt acaagaatat attgcgacag gaattccgct gaatgccgac atttcaagtc
    18121 aactactcat caatattttt attccgaata cgccgcttca tgatggagct gttatcgttg
    18181 gtcagaataa gattgtggca gcctgtgctt acttgccttt gtcagaatca aaggcaattt
    18241 ccaaagaatt tgggacccgt catagagcgg ctattggatt atctgaaaac tctgatgcac
    18301 taactatcat tgtttcagaa gaaacaggag ctatttcagt aactcgcaaa ggccaatttt
    18361 tacacgattt aagcacagat gaatttgaaa cggtacttag gacctacctg atgagtaatt
    18421 caaatgttac tttaccatgg tataagaaaa ttctaggagg gaaatctaaa tgaaacgatt
    18481 tttaaatagt cgtccttggt taggaatggt atcagtcttt tttgcgattc tccttttttt
    18541 aactgcagca tcgagcaatc ataataactc tagctcgcaa atctatagtc cgattgaaac
    18601 ctatacgcat agccttaaag atgtaccaat tgatatgaag tatgatagtg acaaatattt
    18661 tatcagtggg tattcttatg gtgcggaagt ttatctaacc tccactaatc gtatcaaatt
    18721 agattctgaa gtgaacaatg atacacgtaa ttttaagatt gtggcggatc taacacatag
    18781 tcatccaggt acagtaagtg tcaacctaag agtagaaaac cttccttctg gggtgacagc
    18841 taccgtatct ccagataaaa tatcagtcac aattggcaaa aaagaatcta aggtatttcc
    18901 tgttagagga agcgttgatg ctaaacaaat tgcaaatggt tatgaaatta gcaaaattga
    18961 aacgggggtt aataaggttg aagtgaccag tgatgaatct accattgctt taattgatca
    19021 cgttgtggca aagttacctg atgatcaagt gttagatagg aattatagta gtcgagtgac
    19081 cttacaagct gtctcagctg atggaactat tttagcaagt gcaattgatc ctgcaaaaac
    19141 aaatttatca gttgctgtaa aaaaaataac gaaatcagtc ccgattagag ttgaggcagt
    19201 ggggatgatg gatgatagct tatcagatat tcaatacaaa ttgtcaaaac aaacagctgt
    19261 tatctcaggt agtcgagagg tcttagaaga tattgatgaa attattgcag aagttaacat
    19321 ttctgatgtc actaaaaata ctagtaagac cgtgagtttg tcttctagtc aggtgtcaat
    19381 tgagccgtca gtagtgaccg ttcagttgac aaccaccaaa aaataatgga taataactag
    19441 gaaaattgaa tggaggaagc cattaggctt atataaatta tgggaaaata ttttggaaca
    19501 gatggtgttc gtggcgaagc aaatgttgag ctgacacctg agttagcttt taaactgggc
    19561 cgattcggtg gttatgtttt aagtcaacat gagaccgaaa gacctaaagt ttttgtggcg
    19621 cgtgacaccc gtatttcagg agaaatgttg gagtcagcct tgattgctgg tctactatct
    19681 gttggtattg aagtttataa acttggcgtt ttagcgacac ctggtgtctc ttatttagtt
    19741 agaacagaaa aagcaagtgc aggtgtgatg atttctgcaa gtcataaccc tgcgcttgac
    19801 aatggcatca aattctttgg gaatgatggg tttaagttag ctgatgacca agaattggaa
    19861 attgaagctc tcttagatgc tccggaggac acgcttcctc gcccgagtgc agaaggactt
    19921 ggaaccttgg tagattatcc agaaggactt cgtaaatatg aaaagttctt ggtaacaact
    19981 ggtactgact taagcggtat gacagttgcc ttagacactg ctaatggagc tgcttcagtg
    20041 tcagcacgtg atgtcttttt agatttaaat gcagaaattg ctgtcattgg tgaaaaacca
    20101 aatggtctta atattaatga cggtgttggt tcaacgcgtc cagaacaact tcaagagtta
    20161 gttaaggaaa caggagcaga tcttggttta gcctttgatg gcgatagcga ccgtctgatt
    20221 gctgtggacg aaactggcga gattgttgac ggtgatcgta ttatgtttat cattggtaaa
    20281 tatttgtcag aaaaagggct tcttgctcac aataccattg tcacaacggt gatgtctaac
    20341 ctcggttttc ataaagcttt agataaacaa ggtattaata aagcaattac agcagttgga
    20401 gaccgctatg tggttgaaga aatgcgtagc tcaggataca atctcggtgg tgaacaatca
    20461 ggccatgtca ttatcatgga ctacaatacc actggagatg gtcagttgac agctatccaa
    20521 ttagccaagg tgatgaagga aactggaaaa tcactttcgg aattagctgc tgaagtaacc
    20581 atttaccctc aaaaactggt gaatattcgt gtggaaaaca gcatgaaaga acgtgctatg
    20641 gaagttccag ctattgcgaa catcattgca aaaatggagg atgaaatggc tggtaatggt
    20701 cgtattctcg tgagaccaag tggtacagaa cctcttcttc gtgtcatggc agaggcgcca
    20761 acagatgccg aagttgatta ttatgtcgat actattgctg atgtcgtccg tacagaaatc
    20821 ggatgcgata actaacgagt tgagtacaaa caagaaacct tatttctaag gcttctgtca
    20881 acaattggaa agaggcttgg ggcgtttagc ccaagtctct ttttataaat tgttataaat
    20941 tgctaaagta gaagagaaag gatattggat gacaaaacag caaatcgaaa aactagcgga
    21001 cttactgcct ccttttgcag ccacacttta cttagacatg attcctgaat ttcaagaagg
    21061 ttatgcttct tatgtttatc aaacaccaaa acaagatatt caaaagcgcc gcatcaagca
    21121 gttaactaaa aattttgaac gattactaga taccccatct ttttatgtga tgcctgtgac
    21181 aagaaaaaca gcagagcaat tgctagcaga taaaggccta gcttatcatt tgttatcgac
    21241 agttgcagct aatcaagtgt ttgcggctgc tgttaacgag gatcagatgc tttttcaagt
    21301 gcttcgaaat ggagcaagag tagcctttgt gattcttcaa gaaaaggggg aatttctaga
    21361 aatgacttta gggattcttg aaacagtgac agaaaacgag gttccagcag ctattgtgga
    21421 ggctgtccag acatatcttc tggcagatat gcaagagaaa ctcccttctt taagcattat
    21481 ggtcagtcaa gaatcaagca agctttttta ccaagaacaa gggtttgttt tgctagctaa
    21541 gggttgcaag ccaggaaacg aaaatgattc tgacgtttgt cagctcgtaa aatacttttc
    21601 caagccatga agaatcaagg gaaatggttt attcatagaa acattttatc atcaaagtgg
    21661 tataataaga ccatgtcaaa aaaacctact tcagcctatg tgcacattcc tttttgcaca
    21721 caaatttgtt attattgcga tttttcaaaa gtctttatcc aaaatcaacc tgttgatgct
    21781 tatttgaaag ccttgattca agaatttgac tcttatggca ttcgagacct aaaaaccctt
    21841 tatattggag gaggtacgcc tacagctatc actgctaaac agttggagta tctcctaaat
    21901 caccttgaac gaaacctcaa tttagatgat cttgaagaat tcacaattga ggcaaatcct
    21961 ggtgatttga cgccagaaaa aattgcggtg cttcagaggt cagctgtcaa tcggatttcc
    22021 ttgggggtgc agacttttaa taacaagcaa ttaaagcaga ttggccgtag ccataatgaa
    22081 gaacaaattt atagcaccat tgccaattta aaaactgcag gctttcacaa tatttccatt
    22141 gatttaattt atgccttgcc aggtcaaacc ttagatcaag tcaaggaaaa tgttgctaaa
    22201 gctttggcac ttgatattcc ccaccttagt ctttatagcc ttattttgga acatcacact
    22261 gtttttatga acaaaatgcg acgtggtaaa cttaacttac caacggaaga cttggaagcg
    22321 gaaatgtttg agtacattat ttcagaaatg gaagctaatg gttttgagca ttatgaaatt
    22381 tccaatttta ccaaaccagg ttttgaaagt cgccataact tgatgtattg ggataatgtg
    22441 gagtattttg gatgtggtgc aggggcttca ggttacctta atggcattcg ttatcagaat
    22501 cgggtgccca tccagcatta tcttaaagcg gttgaagcag ggaatgctag actaaatgaa
    22561 gaagtgctgc gcaaagagga aatgatggaa gaggaactct ttttgggctt acgtaaaaag
    22621 acaggagtct ccatccagcg gttccaagaa aaatttggta tgtcttttga ggagcgttat
    22681 ggaaatattg ttagggagct tcaaaaccaa ggactgcttg tcaaagatga cgcctttgtc
    22741 agaatgacta aaaagggtct tttcttaggt gattctgttg ctgagcggtt tatattagat
    22801 taggagagta ttatgggatt aagttatcag gaggagttga cacttccttt tgaattatgt
    22861 gatgtcaaat cagatataaa attgcccctt ttattagact attgtttgat ggtttctggt
    22921 agacagtctg cgcaattagg acgaagtaac aacaatcttt tagttgatta caagcttgtt
    22981 tggattgtaa cggattatga gatcactatt catcgcttgc cacattttca agaaaccatc
    23041 accattgaaa caaaagccct ttcctataat aaattttttt gttatcgcca attttatatt
    23101 tatgatcaag aggggggtct tttagtggat atcttagcct attttgcttt gttaaaccca
    23161 gatacgcgaa aagtggcaac tattccagaa gatttagtag cgccatttga gactgatttt
    23221 gttaaaaagc tacaccgtgt tcctaaaatg cctcttttag aacaatcaat tgatcgtgat
    23281 tattatgtgc gttattttga tattgatatg aatggtcatg tcaacaacag taaatattta
    23341 gattggatgt atgatgtgtt ggggtgtgag tttttaaaaa cgcatcagcc tcttaagatg
    23401 actttgaaat atgttaaaga agtctcacca ggcggtcaaa ttacttccag ttaccatttg
    23461 gaccaattaa cttcttacca tcaaatcacc tcagatgggc agctgaatgc ccaagccatg
    23521 attgaatggc gagcgattaa acaaacagaa agcgagacag actagtgcct tataagggtt
    23581 atttaattga tttagacgga acgatttacc aagggaaaaa ccgtattcca gcaggggagc
    23641 ggtttatcaa acgcctacaa gaaagaggca ttccctattt attagtgact aataatacca
    23701 caagaacacc cgaaatggtg caaagcatgc tggctaatca gtttcatatt gagacaagca
    23761 ttgagaccat ttatacggct accatggcaa ccgtcgatta catgaatgac atgaaccgtg
    23821 gcaagacagc ttacgttatt ggagaaacag ggctcaaatc agctattgca gcagcaggtt
    23881 acgtagaaga acttgagaat cccgcttacg tggtggttgg tttagacagt caggtgacct
    23941 atgagatgtt ggctatagcc accttggcta ttcaaaaagg tgccctcttt attgggacaa
    24001 atcctgattt aaacattcca accgaacgtg gtttgatgcc aggagcaggt gcattgaatg
    24061 ccttactaga agctgccaca cgtgtaaaac ctgtttttat tggcaagccc aacgctatca
    24121 ttatgaataa atcactagag gtattgggca ttcagcgctc tgaggctgtc atggttggcg
    24181 ataattactt gactgatatc atggcaggta ttcaaaatga tattgcaacg atcctcgtga
    24241 caacaggctt taccagacct gaagaggtac caaccttacc aattcagcca gatcatgtcc
    24301 tatccagcct tgatgagtgg aggttgtgat ggtagaaaac actaaattac tatgtagctg
    24361 ggtatggtta ttagcgttag ctattctcat aacgatctat tcaacgtggc tgtggtatcc
    24421 tcttgaggtg gaccatctaa agttagaaca agttgttttt atgagcaagg atgctatctt
    24481 gcataactat aacggactac tcaattacct caccaatcct tttgtgacaa ggttggaatt
    24541 tgctaatttt cactcatcgg cagacggact caagcatttt gcagatgtga agtggctttt
    24601 tcacctaact caagtcgttt ttcttggcct tctttaccca acccttaaga ctttcacaca
    24661 aaggttaaaa accaaacgtt tctggctcct tcaaaaacct ttaatactag cagctttgtt
    24721 tcctcttatg attggtctaa tggctagttt cattgggttt gaacattttt ttactctttt
    24781 tcatcaggtg ctttttgtag gagatagcag ctggctcttt gatcccttga aagattctgt
    24841 gatttggatc cttccagaag tctttttctt gcactgtttc cttttcttta tgatagttta
    24901 cgaaatcatc ctgtggagct tagtaggttt agcaagatgg cagcgcctaa atgtagaatg
    24961 ataaaaggat taagagatta atttccctaa aaatgataaa acaagcgttt tgaaagcgct
    25021 tgtttttttg gtttgcagtc agagtagaat agaagtatca aaaaaagcac cgactcggtg
    25081 ccactttttc aagttgataa cggactagcc ttattttaac ttgctatgct gttttgaatg
    25141 gttccaacaa gattatttta taacttttat aacaaataat caaggagaaa ttcaaagaaa
    25201 t
//
LOCUS       DAUGJR010000027        25175 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUGJR010000027 DAUGJR010000000
VERSION     DAUGJR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25175
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.027"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            104..352
                     /locus_tag="VH800_001146"
     CDS             104..352
                     /locus_tag="VH800_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8362220.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLSKTNN"
     gene            389..1000
                     /gene="amaP"
                     /locus_tag="VH800_001147"
     CDS             389..1000
                     /gene="amaP"
                     /locus_tag="VH800_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEQ8362221.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFNIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1011..1199
                     /locus_tag="VH800_001148"
     CDS             1011..1199
                     /locus_tag="VH800_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEQ8362222.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1212..1751
                     /locus_tag="VH800_001149"
     CDS             1212..1751
                     /locus_tag="VH800_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8362223.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1792..1992
                     /locus_tag="VH800_001150"
     CDS             1792..1992
                     /locus_tag="VH800_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8362224.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2003..2491
                     /locus_tag="VH800_001151"
     CDS             2003..2491
                     /locus_tag="VH800_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8362225.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2654..3295
                     /locus_tag="VH800_001152"
     CDS             2654..3295
                     /locus_tag="VH800_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8362226.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICNQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3438..3980)
                     /locus_tag="VH800_001153"
     CDS             complement(3438..3980)
                     /locus_tag="VH800_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8362227.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4098..4799
                     /locus_tag="VH800_001154"
     CDS             4098..4799
                     /locus_tag="VH800_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362228.1"
                     /translation="MAFIELKQVSKSYQIGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMAQTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4814..7450
                     /locus_tag="VH800_001155"
     CDS             4814..7450
                     /locus_tag="VH800_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8362229.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSHLRLTNAFS
                     KDYQKKVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSTLISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLILTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSDTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7542..8138
                     /locus_tag="VH800_001156"
     CDS             7542..8138
                     /locus_tag="VH800_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8362230.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDVADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8149..9105
                     /locus_tag="VH800_001157"
     CDS             8149..9105
                     /locus_tag="VH800_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8362231.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9202..10542
                     /locus_tag="VH800_001158"
     CDS             9202..10542
                     /locus_tag="VH800_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEQ8362232.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELKKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALVKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10658..11542
                     /gene="truB"
                     /locus_tag="VH800_001159"
     CDS             10658..11542
                     /gene="truB"
                     /locus_tag="VH800_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEQ8362233.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACNKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11571..12503
                     /locus_tag="VH800_001160"
     CDS             11571..12503
                     /locus_tag="VH800_001160"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEQ8362234.1"
                     /translation="MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12546..12950
                     /locus_tag="VH800_001161"
     CDS             12546..12950
                     /locus_tag="VH800_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEQ8362235.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            12952..13230
                     /locus_tag="VH800_001162"
     CDS             12952..13230
                     /locus_tag="VH800_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEQ8362236.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13220..14008
                     /locus_tag="VH800_001163"
     CDS             13220..14008
                     /locus_tag="VH800_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEQ8362237.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAITLEDQ"
     gene            14011..15321
                     /locus_tag="VH800_001164"
     CDS             14011..15321
                     /locus_tag="VH800_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEQ8362238.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALAMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLIKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
     gene            15460..16326
                     /locus_tag="VH800_001165"
     CDS             15460..16326
                     /locus_tag="VH800_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEQ8362239.1"
                     /translation="MKMKKKFFLLSLLALSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            16337..17272
                     /gene="pstC"
                     /locus_tag="VH800_001166"
     CDS             16337..17272
                     /gene="pstC"
                     /locus_tag="VH800_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEQ8362240.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            17262..18149
                     /gene="pstA"
                     /locus_tag="VH800_001167"
     CDS             17262..18149
                     /gene="pstA"
                     /locus_tag="VH800_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEQ8362241.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSAHFIGKKLHSKMTAAK"
     gene            18165..18968
                     /gene="pstB"
                     /locus_tag="VH800_001168"
     CDS             18165..18968
                     /gene="pstB"
                     /locus_tag="VH800_001168"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362242.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            18981..19739
                     /gene="pstB"
                     /locus_tag="VH800_001169"
     CDS             18981..19739
                     /gene="pstB"
                     /locus_tag="VH800_001169"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362243.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            19807..20460
                     /gene="phoU"
                     /locus_tag="VH800_001170"
     CDS             19807..20460
                     /gene="phoU"
                     /locus_tag="VH800_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEQ8362244.1"
                     /translation="MLRMKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            20665..23202
                     /locus_tag="VH800_001171"
     CDS             20665..23202
                     /locus_tag="VH800_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEQ8362245.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTLRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQPTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            23548..24222
                     /locus_tag="VH800_001172"
     CDS             23548..24222
                     /locus_tag="VH800_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8362246.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTCFVNRLQTLRSVGY
                     ILKNNE"
     gene            24215..>25175
                     /locus_tag="VH800_001173"
     CDS             24215..>25175
                     /locus_tag="VH800_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8362247.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVGVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN"
BASE COUNT         7995 a         4163 c         5175 g         7842 t
ORIGIN      
        1 cactttttga aagtcgacta ttaaaagact attgcttgaa gaatgacagc tgttattctt
       61 ccttggacaa aaggtacagg agtatctaaa aaggagaatt atcatgggac ttatttggac
      121 tttaatcgtc ggtgcgctta ttggtgtgat tgctggagca cttactaaaa aaggtggttc
      181 aatgggctgg attgcaaaca tcgctgctgg tctagttggt tcttccgttg gtcaagcttt
      241 acttggttca tggggccctt ctttagcagg aatgtctttg atcccgtcag ttattggtgc
      301 cgttatcgtt gttatgatca cttcttttgt actaagcaaa actaacaact agtttcctct
      361 ttatttagta agtacttaca aatagagaat gttaagtaga aaagaggtct gtatgtcaaa
      421 attgttaaag attagttatt gtcttgtcgg acttgttcta ttgtctgttt ttggatgggt
      481 agttggaata accggaggct atatatattt accttatagt tatcgttggc taagttgggg
      541 tatggatagt tttcccaatc tcttagattc agctttatcc tattattact tctggacagc
      601 ccttgtatta tttgttataa catttcttgc cttattagtt attattttat acccaagaat
      661 ttatactgag gtccagttac gccataaaaa taaaaaagga acacttttat taaaaaaatc
      721 ggctattgaa agttatgttg cgaccgctat tcaaactgca ggtttgatgc caaacccaac
      781 agtcacagct aaattatata agcggaagtt taacattatc gttaaaggac gtttagcttc
      841 tcgtgtagca gtggcagatc aaattagtgg cgtgaaagaa gggatcgaaa aaggtttaac
      901 cgagttcttc ggaattaatt atcctgttaa tttcaaagtt tatgttaaag atattgctga
      961 ttctgatcgt aaacatatta ccagaaatcg tgtagaatag gagatctatc atggaatttt
     1021 atgaaaaatt caagtaccct attattggtg gcttggtggg gctaattatt gccatattgc
     1081 tcatggcttt tggtttattc aaaacgctac tagcaattat tttcattatt ttaggaatat
     1141 atggtggcct gtatgccaaa aaaacaggta ttattgatca atttcttaat cgtaaataaa
     1201 ggagacttat tatgactgaa acttatatta aaaacacatc taaagactta acttcagcaa
     1261 ttcgtggcca attaacatat gatgataaag taattgaaaa aattgttggt ttagcacttg
     1321 aaaatgttga tgggttactg ggtgtaaatg gtggtttttt tgctaaccta aaagataaat
     1381 tagtaaacac cgaatctgta cgtgatggcg tgaacgtgga agttggaaaa aaacaagttg
     1441 ccgttgatct tgatattgtc gctgaatatc aaaagcatgt gccgactatt tatgactcta
     1501 ttaaatcgat cgttgaagaa gaagtgaaga gaatgaccga tctggatgtg attgaagtta
     1561 atgttaaagt agtcgacatt aaaacaaaag aacaatttga agctgaaaaa gtaagtttac
     1621 aagacaaagt ttcagacatg gcacgttcaa catctgaatt tacgagtcat caagttgaga
     1681 atgttaaagc ttcagtggat aacggtgttg aaaaacttca agatcaaaaa gctgagccac
     1741 gtgtaaaata atcatatgtc gtcaattagg taagctaaag gagggtttat tgtgtcagat
     1801 gaaaaatata atgcgaaatt agatcaagct ggtggcaagt taaaagaagg atttggtaag
     1861 atttctggag ataaatcttt agaaactgaa ggtaaagtag ataaagttac tggaaaagtt
     1921 aaagaggtta ttgcagacgc caaagatact gtaaaaggat tagctaaagg cttagataat
     1981 aaagataaat aaaggggaca tgatggaaaa aactcaaatt aaaagcactc ttacttatga
     2041 cgataaggtc atcgaaaaaa ttgtcggtca tgctttggaa aacgttggcg gattactagc
     2101 tgtaacaggt ggatttttct caaatatcaa aaataatttg gtgaattctg agtctgtaac
     2161 tgatggtgtt tcagttgaag ttggtagcaa ggaagtagca gttgatttag caatcattgt
     2221 agaatacggt aaagatattc ctgctattgc agaatctatt aaagctattg tttctcaaaa
     2281 cgttgacagt atgacacatt tgaaagttgt tgaagtcaat gtgaacgttg ttgatattcg
     2341 tactaaggaa gaacatgaag ctgctagcgt tactgttcaa gatcgtgtca ctagtgcagc
     2401 ttcaagtact tcacaatttg tatcagaaca aacagaaaaa ttaaaagata ctatctctga
     2461 tactgtaaat agtgatgagg cagctaaata agcaatcgtc taggaagtat tattgactgg
     2521 tggtgataag tttgagctgg tatttaccag ctctttttgt cacggttaaa aagatacgga
     2581 ctattgtcat ctctctaaaa atatgattta attagatata aatttttcaa attattagaa
     2641 aggagtaaat taagtgataa gtcctaaaaa agagataaca agttcaaaat atcaaaaaat
     2701 tgctatttca gtagctcagc gtatcgcaaa tggcgaatat gaagtgggcg aaaagttaaa
     2761 gtcaagaact actatcgcct cgacatttaa tgtatcacca gaaacggctc gtaaaggcct
     2821 gaatatttta gctgacttga aaattttgac tttaaaacat ggtagtggag ctattgtgct
     2881 gtcaaaagaa agagctattg agtttataaa tcaatacgaa tcaacccatt ccatcgctgt
     2941 tttaaaagaa aaaatacgtg agactattaa tgatcaggga aaagcaatgg aaaaaatggc
     3001 tgttttggtt aatgattttt taatgcaaag tcaatctgtt agtaagcaat acccattagc
     3061 accttatgag attatttgta atcaagattc ggaacatttt ggcaaatcta ttggtgtgtt
     3121 aaatatctgg caccagacag gagcaactat cgtcgctatt gaacatgctg gtcagtttat
     3181 cgtttcacca ggtccttatt ctgttattga aaaaggcgat catatttatt tcgttggtga
     3241 tgagtcagtc atttcacgaa tgaagacctt ttttaattta cgaaaaggat tataagtttg
     3301 agggcccacc tcaaactttt tttgttgctg ttgagcatta ttaaaagagg cagatcatca
     3361 tggtttgtct ttccaaaata tctgtttaga cagttgtttg ggattgggag catgatttca
     3421 gactcttttg atgtttttta attgtctaga gtaactgctt tgagaataat atcggcaacc
     3481 tcttcagtgg tttcttgata gccattagca atccaatagc tgataatgct ctcaatactg
     3541 gcaaggtaaa cttctaaagc atagggataa ggaatatggt attgattggt cacaatgtct
     3601 tggaaaccag taatagtagt caaaaattgg taacagaaat ccttgatgag ttgcggaaat
     3661 ttgaggtaag aaatagtagc gagtgcggtt ataaattctc tatgttctat aaggtaggac
     3721 aaggtttgat tgaggacttg tcgagtgtct gtgtagattt cagcctgatt taacaaacgg
     3781 tacaaatcat ccagagtgtc atttttgaag tgattcatca tgtcaaattt atcagtgtag
     3841 tggaggtaga aggttcctct attgatacca gcctttttag taaggtcaga gacagtaaga
     3901 gtttcaaaag attgttcagt tagtaaggtg gttaaggcgg tctttacata agctttggtt
     3961 tcagtatgtc ttttggtcat tctcaggtgc tccttaaatc aacagttgcg tcagatttgt
     4021 tcttgttaaa tacttagggc cattatataa taaggctata attaaatcaa cactatgttc
     4081 aaataatgga ggggcagatg gcttttattg aattaaaaca ggtttcaaaa tcttatcaga
     4141 taggagagac gactgttttt gccaaccacg aagtgtcttt tgagattaat aaaggagaac
     4201 tagtggttat tttgggagca tccggagctg gtaaatcgac agtcctcaat attttggggg
     4261 gcatggacac agtagatgca ggtcaagtaa ttattgatgg caaagacatt gctcattaca
     4321 cgtctaaggc cttaactcag tatcgtcgga atgctattgg tttcgttttt caattttata
     4381 atttggttcc taatttgaca gctaaagaaa atgttgaatt agcagttgaa attgtagcag
     4441 atgctttaga tcctgtgacc attttaaagg aagtaggact cagtcatcgt ctggatcatt
     4501 ttcctgctca gctctcaggt ggtgaacagc aacgggtttc gatagcacgt gccttagcta
     4561 aaaaccctaa attgcttctt tgtgatgaac ctacaggtgc ccttgactac caaacaggaa
     4621 agcaaattct aaccctctta caggatatgg cacaaactaa ggggaccacg gtagttattg
     4681 taacccacaa tgctgctatt gctccgatag ctgatcgtgt catttttatg catgatgcac
     4741 aggttaccaa gacagtcatt aataaggaac ctgcaagcat tgagacaatt gattattaag
     4801 aggaaggtgt cgtatgataa agaaaacctt atggaaggat attttgagag ctatcaagaa
     4861 tagtaaaggg cgattcattt ccttattttt cctaatggcc ttaggctcct ttgctttagt
     4921 tggacttaaa gtcaccggtc cagatatgga acgaacagcc agccgttacc tcgaaagaca
     4981 ccaggtgatg gacctaacgg tactggcttc tcatcaattt tcccaagccg ataaacaaga
     5041 gttagatacg ttaaaagggg ctcatttaga atatggtcat ttacttgatg tcagtctaac
     5101 tagcaaccag aaatctctta ggctctatag cgtgccaaag aaagtgtcta agccagtctt
     5161 ggttaaaggg agttggccaa agcgagagac agatttggtt ttatcctcct cacttgctaa
     5221 aaactatcag attggagatg aactagcagt cacctcacct atggaaggtt tgctgacgac
     5281 aacccatttt caagtggttg gttttgcgaa ttcttcagaa gtttggtcca agtccaattt
     5341 aggaagttcc tcaaccggag atggaagtct ctacgcttat gcttttgtta atccaaacgt
     5401 ttttaaaagt gcctttaacc tgctgcgcat ccgttttagt catcttcgtc tgacaaacgc
     5461 tttttccaaa gactatcaaa aaaaggtaac ccaaaaccaa gctcatttgg ataatctact
     5521 taaagataat ggccagaagc gttatgatga cctccaaaat cagtatgacc ttgccttaaa
     5581 aaatggcaga gcagcacttg caaaggaaac agtgaaacta gctgcgagtg aggagaactt
     5641 aactttttta gaaggctctg ctttacaaga agctaagcat cagattgaac aaggcaaaca
     5701 agcattagcc aaggaggaaa agcagttaga gcaggtgcag gctacaaaag ataagctaga
     5761 aaaacccagt tacctgactt ataatcgctc gaccctacca ggaggagaag gatatcatac
     5821 ttatgcaact tcaacgacct ccatttcaaa tgttggaaat atttttcctg ttgttcttta
     5881 tctcgtagct gctctagtag cctttaccac catgacacgt tatgttgatg aagaaagaac
     5941 aagctctggt ctattaaaag ccattggtta ttctaacaag gatatcagtt taaagtttct
     6001 tatctatggg cttttagcca gttttttagg gacaacttta ggtattattg ggggaactta
     6061 cctcttatct accttgattt cagagatctt aacaggagct ttgactattg gaaagactca
     6121 cctttatagt tattggtttt ataatggcat agcttacttg ctggctatgt tatctgctgt
     6181 tttaccagcc tacttaattg tcaaaaagga attattcctc aatgcagctc agttattgct
     6241 gcccaaacct cctagtaagg gggcaaaaat ctggttggaa caccttactt ttgtctggaa
     6301 agccctgtcc tttactcaca aggtgaccat acgtaatatt tttcgctata aacaaagaat
     6361 gctgatgacc attgtaggcg ttgcaggctc agtagccctt ttatttgcag gcttagggat
     6421 tcagtcgtca ttagccaaag tagttgagca tcaatttggt gatttaacga cttatgatat
     6481 tttggctgtc ggttcggcca aagcgacagc gacagagcaa actgacttag ctagctatct
     6541 taaacaagaa cctattacag ggtaccaaaa ggtatcttat gccagcttaa cccttcctgt
     6601 aaagggatta cctgataagc aaagtatttc cattttatca agttcagcta cttctcttag
     6661 tccctatttt aatctgctgg atagtcagga gcaaaagaag gttcccattc caacctctgg
     6721 tgttttgatt tctgagaaat tagcctccta ttacaaggta aaaccaggtg atcagttgat
     6781 attgactgat cggaaaggac agtcttataa agtgacgatt aaacaggtta ttgacatgac
     6841 agttggccat tacctgataa tgtctgatac ctattttaag aatcatttta aaggattgga
     6901 ggctgctcct gcctatctga ttaaggtaaa agacaaagat agcaagcaca taaaggagac
     6961 agccagtgac ttgttaacct taaaagcgat tagagcagtt tcacaaaacg tcaatcatat
     7021 taaatctgtt cagctagtag tcacctctct taatcaggtc atgaccctcc ttgtcttctt
     7081 gtctatttta ttagcaatcg ttatccttta taacttaacg actattaata ttgctgagcg
     7141 tattcgagaa ttatccacta ttaaagttct gggattttac gatcaggagg tcaccttata
     7201 tatttatcga gaaactattt cgctatccct agtaggcatt cttttaggta tctatttagg
     7261 aaaaggcctg catacttata tcatgacaat gatttcaact ggggatattc aatttggtgt
     7321 aaaggttgat gcttatgttt atctagtgcc aattctagta atccttagct tgttagcggt
     7381 attaggtatc tgggttaatc gccatttaaa aaaggttgat atgttagaag ctttgaaatc
     7441 catagattga ttggtgaaaa gacagatata gacagcgctt gaaaagttaa tcatattatg
     7501 atagtatcta aatactataa tttaatagaa agatactatg tatggaaaat agcattgagg
     7561 cctatctagc agatagcaga gaaaaggtaa cattaggcac agttgttgat tgttttaaag
     7621 gaaaagcagt ctcaagtaag gttgtgccag gtgatgtggg attgattaat ttatctgaca
     7681 tgggcacctt agggattcaa tatcaccaat taagaacttt ccagatggat cgtaggcagc
     7741 tcttgcgtta ccttttggaa gacggagatg tcttaatcgc ctctaaggga accctaaaaa
     7801 aagtctgtgt ttttcataag caaaatcgag atgtggtggc atcatcaaat atcactgtct
     7861 tacgccctca aaaactgtta aggggctact atatcaagtt ctttttggac tcacctattg
     7921 gtcaagcgct cttggatgta gcggaccatg gcaaagatgt gatcaatctc tcaacgaaag
     7981 aattgttgga tattccaatt cccgttattc ctttagtgaa acaggactat ttgattaatc
     8041 actacttgag aggattaaca gattatcatc gtaaactcaa tcgagcagaa caggagtggg
     8101 aatatattca gaatgaaatt caaaaaggat taggttagga gtcttgtcat gggttcagtt
     8161 gaacgtacat taaaaatgac cttggctacc attgttgcca ttttaattgc ttaccaactt
     8221 catctggatt atgcaatgtc agcggggatc attgccctgt taagtgtttt agacacccgt
     8281 aagtccagtt tggtggtcgc taggaatcgc ttgctatctt ttttcctggc ttttgggatt
     8341 gcgatgatgt gctttagctt gtttggtttt acgacagtag gttttatgtg ttatttgtta
     8401 attattattc ctttgctcta tcactttcag atagaggcag gactggttcc tataacagta
     8461 cttgtgacac atttgattgc taaaaaaagt attgcattac ctattttatc gaatgagttt
     8521 atgctctttt ttgtagggac tagtgtcgct ttactattta atgcttatat gggtccacaa
     8581 gatcagcaaa ttcggtacta tcaccaaaaa gttgaatcgg atctgaaagg tatcttatac
     8641 cgttttgaaa gctttctact ggaaggaaaa ggtcaaaatg aagggctctt gatcaaaaac
     8701 cttgataaaa tattagatga agctctaaaa ctagtttatc gagaaaggca taatcaacta
     8761 tttcagcaga ccaattatca agttcattat tttgagatgc gacgacaaca aaatagacta
     8821 ttgggacaaa tggctatcaa cgtaaacacg ttaatgagac aaagtaagga aagtattctt
     8881 ttgtcacatc tttttcacga aactgcttgt cagctaagcg aacaaaatcc ggctttaacc
     8941 ttgattgatg acatcgaaca attgcttgaa acctttcgtc atggtgatct tcctcaaact
     9001 cgggaggaat ttgagcgacg tgcggtttta tttcagctct tacaagactt agagcgcttt
     9061 atcttattaa aggtagagtt ttatcaggat tatcaaaatg actaaatctc tattgcacac
     9121 ttcttatcta tgacagcttg ggacttaact tcctgagctt ttttgctata ataaaatgaa
     9181 gaatctcaga atggagacaa gatgaacgaa ataaaatgcc ctcattgtca taccctattt
     9241 actatcaatg agtcagagta tagtcaatta ttggaacaag tcagagggca agcctttgat
     9301 gaagaattga aaaaacggct aatcaatgag atagccttgc tggaagaaaa agcgaagcat
     9361 caattgcatg aggttgtcgc aaaaaaagaa acagctatta ccagcttgac aaaccaatta
     9421 gagcaaattg aaaaagaaca agcctacctc agacaagaag aactggctaa aaaagaccag
     9481 cttattgctt ctttagaagc gaaacttgat aaattagcct cgcaaaatgc tttggaactg
     9541 gccaatcaat tagctgagaa ggacaaagaa gtggttagtt tgaccaatca gctggacaaa
     9601 ttagcacttg aaaaagatgc cacgttccag tcaaaacttg ctacaatcga aaaagaacgc
     9661 gatggaatca aaaaccaatt ggcgcttcaa gctaaagaaa gtgaattgtc gttggcttcg
     9721 gtgcgcagcg actacgaagc acagttaaaa gcggctaacg agcaagttga attttataaa
     9781 aatttcaaag cgcagcaatc taccaaagca atcggagaga gtctagaact ctatgctgaa
     9841 acagagttta acaaagtaag aagctatgct ttccccaatg ctagctttgt caaagataac
     9901 caattgtcta gtcgtgggtc aaaaggggac tatatttacc gagaggttga tgccaatggt
     9961 gtagaaatcc tctctatcat gtttgagatg aagaacgagg cagacaccac caaaacaaaa
    10021 cataaaaata gtgatttttt caaggagtta gataaagacc gtcgcgaaaa agattgtgag
    10081 tatgctgttt tggtaagcat gttagaagct gataatgatt actacaatac agggattgtt
    10141 gatgtcagtc atgagtatca aaagatgtat gtggttcgtc ctcaactctt tattcagttg
    10201 atagggattc tgcgaaatgc ggccctgaat agtttacact ataagcaaga gttggccttg
    10261 gttaaggaac aaaatattga catcactcac ttcgaagagg atttggacca atttaagaat
    10321 gcctttgcta agaactatca gtctgccagc aacaacttta aaaaggctat tgacgagatt
    10381 gataaatcga ttaaacgcat ggaggaagtg aaacgctttt taaccactag tgaaaatcag
    10441 ttacgcttag ctaataataa attagaggat gtttcagtta aaaaactgac ccgccaaaac
    10501 ccaaccatgc gagagaaatt tgaagccctc aaggaccagt aagcctgaaa gtgagtcttt
    10561 ccctgctaaa attggttaag cgtttatttt ggcaaaactg atgataaagc ggtagaatag
    10621 aatcagtaac aattactaat tagagagaaa aatagacatg ataaatggaa tcattaattt
    10681 aaaaaaagaa gccggcatga cctctcatga cgcagttttt aaattacgga agttattaca
    10741 agaaaaaaag attggacatg gggggacctt agatcctgat gtggtcggtg ttctaccaat
    10801 tgcagttggt aaggctactc gtgtgatcga atacatgaca gaagctggta aagtttatga
    10861 aggacaagtg actctcggtt actcaacaac gactgaggat gctagtggag aggtagttgc
    10921 gaggtcctct ttgccagctg tgctaacaga agaactcgtt gatcaaacga tgacgacttt
    10981 ccttgggaaa atcacacaga ccccacctat gtattcagcc gtaaaggtta atggccgtaa
    11041 attatacgag tatgcgcgtg ctggtgaaag tgtggaacgt cctagaagag aagtgactat
    11101 ttctctgttt gaacgcacca gccctttgaa ttttactgaa gacggtcttt gccgattctc
    11161 ttttaaagtt gcttgtaaca aagggactta tgtgcggacc ttagcagttg atttaggtcg
    11221 agctctaggg gtagagagtc atatgtcctt cttgcagcga tcagcttcag caggattaac
    11281 cctcgagact gcctatactt tgggagaaat tgctgatatg gtttctaaac aagagatgtc
    11341 ttttttgtta ccgatcgagt atggcgttgc tgatcttcct aaaatggtta ttgatgatac
    11401 tgaattgact gaaatttcat ttggtcgccg tcttagtctc cctagtcaag agccactgtt
    11461 agctgctttt catggcgaaa aagtaattgc tattttagaa aaaagagatc aagaatacaa
    11521 acccaaaaaa gttcttattt aaatagtttg agtaagtaga atggataatt atggaaattg
    11581 aatatatcaa agattatcgt gatattaacc aagaagatga tacagtcttg atattgggat
    11641 attttgatgg attacaccgt ggtcataaag ccttatttga caaagcaaga gaggttgcaa
    11701 ataaagaagg gttaaaagta gtcgttttta cgtttacaga gtctccgaaa ttggcttttt
    11761 cgcgtttttc tcctgagtta ttgcttcata ttacttatcc aaagaagcgt tatgaaaaat
    11821 ttgccgatta cggtgtaaat aaattatatt tggttgattt tacttctaaa ttctctaagg
    11881 tctcatctga tcattttata actcattata ttaaaaacct gaaagcaaag catattgttg
    11941 tcggttttga ctataagttt gggcataatc gtacagatag tgattattta accagaaatt
    12001 ttgaaggaca agtttatacc attgaggaaa taaaagaaga tcatcgaaaa atttctgcta
    12061 catggataag gaagcttatt caagaaggta atgtagttaa agcaaaccac ttgttaggct
    12121 atgacttatc gacaagggga agagtcgttc acggggatgc gcgtggccgt actattggtt
    12181 tcccaacagc caatctagct ccaattgaca acacatactt accagctgat ggagtctatg
    12241 ttacaaatgt tattgttgct aataaaatct atcgctctat gacgagttta ggtaaaaatg
    12301 tgacatttgg ggggaaagag ttgcgtctag aagttaacat ttttgacttt gacgaagaga
    12361 tctatggaga aattattgag attgtttggt tagataagat tcgagacatg gaaaaattcg
    12421 agggaatcga agatttgact gatagattgg aatatgataa acgaacagca ttaaattgga
    12481 aaaaagatag caaattatct taaatttttg tataataagg taagtaaatt tgatagagga
    12541 aaaatatggt taccttattt ttatcaccta gctgtaccag ttgtcgtaaa gcaagggcat
    12601 ggttagtaaa acacgaagtt gactttcaag agcataatat tattacaagt ccattaagcc
    12661 gtgatgaatt aatgtcaatc ctctctttta cagagaatgg aacggaggat attatttcaa
    12721 cacgttcaaa ggtttttcaa aaacttgata ttgatgtaga agagctttca atttcagatt
    12781 taattgattt aattgctaaa aatccaagtc ttcttcgtcg ccctattatc atggatcaaa
    12841 aacgcatgca aattggtttt aatgaagatg aaattagagc gtttttatcg agagattatc
    12901 gcaagcaaga actacgtcaa gcaacgataa aagcagaaat tgaggggtga tatgtcaggt
    12961 aattattatt atccacttga cttaagttgg agcactgaag aaatatcctc agtgcttcat
    13021 tttttgaata aagtggaatt agcatatgaa aaaaaagtag atgcaaaaca actcctagat
    13081 agttataaga cttataaaac cattgtcaaa agtaaagctc aggaaaagca aatcgatcgt
    13141 gattttcaaa aagttagtgg ttattcgacc tatcaagttg ttaaaaaagc gaaggcaatt
    13201 gagaaaggat tcttttccct tggaaactaa atacgcattt gcaaggcaaa tcattaaaga
    13261 agcagggctt tttatcaagt caaaaatgtc agagcagcta gatattcagg tgaaaacaca
    13321 atttgatgat ctggttacca atgttgatca agaaactcaa cagttactga tggatcgtat
    13381 tcatcagacc tatccttgtg atgccatttt agctgaagaa aatgacgttc gtcaccccat
    13441 taatcaagga aatgtttggg tcatcgatcc cattgatgga acggttaact ttattgtgca
    13501 gggatcacag tttgcagtga tgattgccta ttatgaacaa ggaattggtc aatttgggct
    13561 tatttatgat gtgatggcag atcaattact agctggtggt ggtgattttg aagttacttt
    13621 aaacggtgat aagcttccag cttaccaaga aaaaccttta gagcgtagct taattggctg
    13681 caatgcaggc atgtttgcca gaaatgatcg taaccttgct catctaattg caaagacttt
    13741 aggtgtaagg gtttatggtg gtgcaggtat ctgcatggtt aaggtcatga agcaggaatt
    13801 actggcctat ttttcattta tccaaccatg ggattacgca gcagcaaaag tactaggcga
    13861 taaactgggt tatgttttac taactattga cggatatgag cctgattttc aaacacgtca
    13921 aaaaatcatg tttgttccta aatgccaact cactaggata gcgtcttttc taacaaagga
    13981 ctctgccatc acacttgaag atcaatagaa atgatgtcat taccaaaaga atttattaac
    14041 acttatcaag caatactagg caaagaatta gaagatttct tggcaagttt taaccaagag
    14101 ccggtcaatg cttttcggat taacccctta aagaatcaac taaaaacctt tgaacacccc
    14161 attccaaata ccttatgggg atattatggt aaactatctg gcaagtctcc agagcatgtg
    14221 tcggggttgg tttattccca agaaccagcg gctcaaatgg tggcacaagt agcggctcct
    14281 caaaagggga gtcgtgtttt agacttggca gctgcaccag gaggaaaatc aactcattta
    14341 ttagcttatt tagacaatac aggtctttta gtcagcaatg aaatttctaa gaagcgcagc
    14401 aaggttttag ttgaaaatat cgaacgtttt ggcgctagaa atgttgtggt gactaatgaa
    14461 tccgcagatc gtttagccaa ggtattttct cattattttg atactatcgt ctttgatgga
    14521 ccatgttctg gtgaaggaat gtttcgcaag gaccctgatg ctattcaata ttggcatcac
    14581 gggtatcccg cagaatgtgc caagttgcaa aaatctattt tagaagacgc cttagccatg
    14641 ttaaaaccag gaggagaatt gatatactcc acctgtactt gggctcctga agaaaatgaa
    14701 gatgttgtgc agtggctctt agagacttat acctttttag aattggtcga tgttccaaaa
    14761 ctaaatggaa tggttagtgg tatcggactt ccagagactg ctagaatgta ccctcatcgt
    14821 tatcaagggg aagggcaatt tgtggccaag ctaaaagata agcgtcaaga aggacaaagc
    14881 actaaactaa aagcacctaa atccaacttg atcaaagacc agttacgtct ttggaaaatg
    14941 tttgaaaaag accatctaaa ccttacccta tcaggaacac tacaaacctt tggtgattac
    15001 ctatacctct tgccagatgg tcttcctgct ttagatggcc ttaaaattgc tcggaacggt
    15061 ttagaattag gcgtcttcaa gaagaaacgc tttgaaccct cttacgcctt gggattagct
    15121 ttaaagcctg atgaggtccg atcatctatt gagcttagag aggaagactt tagaccttat
    15181 gtgtcaggta acgtcattac tttgccccaa tcttatccaa caggctggta ccaattactc
    15241 attaatggca atggtctagg atttgccaag gtcgttgaca agaccatcaa aaataatttc
    15301 cctaaagggt taagatttta gcgtaaaaaa taagattaaa aagttaaata tttaaagaaa
    15361 aaatgctttc aaagcatagg tagatatgtt actataaaga atatgtggca cttagtttct
    15421 acatatatac cctttatttt tacgaatagg aaataaataa tgaaaatgaa aaaaaaattc
    15481 tttttgttaa gtcttttggc cctatcaact ttctttttat ccgcatgttc tagctggatt
    15541 gataaaggtg agtcaataac cgctgtagga tcaacagcac tacaaccctt agtagaagca
    15601 gtagctgatg aatttggaag cagtaatcta ggcaagactg tcaatgttca aggtggtggt
    15661 tcaggtacag ggttgtctca agttcaatca ggagctgtcc aaattggaaa tagtgatgtc
    15721 tttgcggaag aaaaagatgg tattgatgct tctaaattag ttgatcatca agtagctgtt
    15781 gcaggacttg cagttattgc caatcctaaa gtcaaggttt ccaatctcag tagtcagcag
    15841 ttgcaaaaga ttttttcagg agaatatacc aattggaaac aagttggagg agaagatctt
    15901 gcgatttcag tgatcaaccg agcagcaagt tctggctcac gagcaacctt tgacagtgtt
    15961 atcatgaaag gggtcaacgc taaacaaagt caagagcaag actccaatgg gatggttaaa
    16021 tcgattgttt cacaaacacc aggtgccatt tcttaccttt cctttgccta cgttgattca
    16081 tctgttaaat ctttgcaatt aaatgggttt aaggcaaatg ctaagaacgt ggctacaaat
    16141 gattggccaa tctggtccta cgaacacatg tataccaaag ataaaccaac agggttgacc
    16201 aaggaatttc ttgattatat gttttcagat gaagtacaac agaacattgt tacacatatg
    16261 ggatatattt cgataaatga tatggaagtg gtcaaatctc atgatggaaa agtaacaaaa
    16321 aggtaatgga ggaattatgg aaaatcagga attggctaaa aaattagcct caccatcaaa
    16381 gaattcaagg cttgaaacct ttggccgcac cattacgttt ttgtgtctgg ctttgattgt
    16441 ttttatcgtt gcgatgattc tgatcttcgt tgctcaaaaa gggttgtcaa ccttctttgt
    16501 tgacaaggtt aatctttttg atttcttgtt tggaaaggag tggcaaccaa gtgtaaaaaa
    16561 tgcggccggc attccttatc ttggtgctct gccaatgatt acaggatcct ttttggttac
    16621 cattttatct gctattattg ccaccccatt tgccattggc gcagccgttt ttatgactga
    16681 aatctcacct aaatatggcg ctaaattatt acagcctgcg gttgagcttt tggttggaat
    16741 tccttcggtt gtttatgggt ttatcggttt gcaagtgatt gttcctttta tgcgctctat
    16801 ctttggtggc acaggttttg gaatcctatc cggggtctgt gtcttgtttg ttatgatttt
    16861 accaacagtg acttttatga caacagacag tctgcgggcg gtgcctcgtc attaccgcga
    16921 agcgtctatg gctatgggag caacacgttg gcaaaccatt tggcgtgttg tccttaatgc
    16981 agctcgtcca ggaattttta ccgctgttat ttttggaatg gcaagagctt ttggagaagc
    17041 cttggctatc caaatggtag tcggtaactc tgctgtaatg ccaagttcac taacgacacc
    17101 agccgcaacc ttaacgtctg tcttgacaat gggtattggt aacacggtta tgggaacggt
    17161 ccaaaataat gtgctttggt cccttgccct agtcttatta ttaatgagtc tggccttcaa
    17221 ttcccttgtc aaattaatca cgaaagaaag aaagagaaat tatgaacgct aaaaaagtcg
    17281 ataaagtagc aactggtact ctttatacca ttgctggaat tattgtagct attttagctt
    17341 ccttaattct atatatcctt gtccgtggct tgccacacat cagctggtcc tttttaacag
    17401 gaaaatcgtc ttcgtacgaa gctggtgggg gaattggtat ccagttgtat aattccttct
    17461 tcctattgat tgttacttta attatttcca ttcctttatc aactggagcg gggatttact
    17521 tggctgaata tgccaaaaaa ggacctgtta ccaactttat tagaacctgt attgagattc
    17581 tgtcttccct accatctgtg gttgtggggc tctttggtta cttgattttc gttgtgcagt
    17641 ttgaatatgg cttttctatt atttcagggg ctcttgcttt gacggtcttt aatcttcctc
    17701 aaatgacccg taatgttgaa gatagtttac tgcatgttca tcatacccaa agagaagcag
    17761 gattagcttt aggcctgtca cgctgggaaa cggtttttta tgtggttatc ccagaagctc
    17821 tcccgggaat ggtaacaggt attgtcttag cttcaggtcg tatttttggt gaagcggcag
    17881 cgcttatcta tactgctggt caatcagcac cagctctgga ttggtcaaat tggaatccac
    17941 ttagtgttac tagtccaatc tctattttcc gtcaatctga gacccttgct gttcatattt
    18001 ggaaagtcaa tagcgaaggg acaattccag atgctactct tgtatccgca ggaagtgcag
    18061 cagtgctatt aatttttatc cttattttca acttttcagc tcactttatt gggaagaaac
    18121 ttcattctaa aatgacagca gcgaaataag atattggaga aatcatgaca gaatacaatt
    18181 ggaatgaacg tcatatcatc acttttcctg aagaaacgct tgctctagct accaaggatt
    18241 tacatgttta ctatggtgcg aaagaagcta tcaaagggat tgatatgcag tttgaaaaac
    18301 ataaaataac agccttgatt ggtccatctg gttgtggcaa atcaacttat cttcgtagtc
    18361 ttaaccgcat gaacgatacc attgatattg ctcgggttac aggtgagatt ctttatcagg
    18421 gcattgatgt taatcgaaaa gacatgaatg tttacgagat tcgcaagcac ttaggaatgg
    18481 tttttcaaag acccaatcct ttcgctaaat ccatttataa aaacattacc tttgcccatg
    18541 aaagagctgg tgtgaaagac aaaaaagttt tagatgaaat tgttgagact tcactgaaac
    18601 aagccgcgct ttgggatcaa gttaaagatg accttcacaa atcagccttc accttatcag
    18661 ggggtcagca acaacgcttg tgtattgcta gagccatttc tgtcaaacct gatattctat
    18721 taatggatga accagcctct gcccttgacc cgattgcaac gatgcagctg gaagaaacca
    18781 tgtttgaatt gaagaagaat tacacgatta ttattgtgac ccacaatatg caacaagcag
    18841 ctcgtgccag tgattacact gccttcttct atttaggcaa cctcattgaa tatgataaga
    18901 cacgtaatat tttccaaaat gcgcaatgtc agtcaacaaa cgactacgtt tcagggcact
    18961 ttggttagaa aggtaatatg atgacagaac ctattttaca gatcagagac ctttctgttt
    19021 actacaatca aaagaaaacg ttaaaagatg tctctttgga cctttatcca aatgaaataa
    19081 cagctttaat tggtccttct ggatctggga aatcaacgct cttgcgttct atcaaccgta
    19141 tgaatgattt gaatcctgaa gtaaccatta caggctctat cgtctataac ggacacaata
    19201 tttatagtcc aaggacagat acggttgatt tacgcaaaga aattggtatg gtattccaac
    19261 aacccaaccc atttccgatg tctatttatg agaacgtggt ttacggcctt cgcttaaaag
    19321 gtatcagaga taaatcaatc ttagaccatg ctgttgaaag ctctcttaaa ggggcttcca
    19381 tttggaatga agtcaaagat cgtttacatg attctgcggt tggcttatca ggcggacagc
    19441 aacagagagt ttgcatagct agagttcttg ctaccagccc cagaataatc cttttagatg
    19501 aacctacctc agctcttgat cctatctcag ctgggaaaat tgaagaaaca ttattgttat
    19561 taaaaaaaga ttatacactg gctattgtga cccgctcaat gcagcaagcc tcacgtttat
    19621 cagatcgaac aggttttttc ttggagggtg acttacttga gtgtggtcct acaaaagcca
    19681 tgtttatgaa tcctaagcgc aaagaaaccg aagactatat ttctggtaaa tttggttgag
    19741 aaagatgtat atggttgacc cctctgtgtt tttattataa tgactagatt gtaggaagaa
    19801 aaaatcatgt taagaatgaa atttgaagaa gaattagata aattgcataa ccagttttat
    19861 tcaatgggaa cggaagtatt ggcacaaatc aataaaactg ttcgtgcctt tgttagtcat
    19921 gatcgtgaat tggccaaaga agttatcgaa gaagatgaca ctattaataa ttttgagaca
    19981 aagcttgaaa agaaatcgct ggaaattatt gccctacaac agccagtttc gaatgatctt
    20041 agaatggtta ttactgtttt aaaggcatca agtgatattg aacgtatggg tgaccatgct
    20101 gcttcgattg ccaaggccac tattcgtatg aaaggtgagg agcgtattcc agtggttgaa
    20161 gaacaaatca accttatggg aaaagctgtg aaacagatgg tagaagaagc ccttaatgca
    20221 tatatcaatg ctgacgatac aaaagcttat gaaatcgcag cttctgatga gattatcgat
    20281 caatatttcc gtaatatcca aaccttagct gttgaagaaa tccgtaagtc tccagatgct
    20341 gtttttgcag gaaaagaata ttttcaagta ttaatgtatt tggaacgtat tggtgactat
    20401 gctcgcaaca tttgtgaatg gattgtttat cttaaaactg gaaaaattat tgaattataa
    20461 gaaattatgc tataatgaga ctgggaaaca gcttgccagt ccctggtttt atacgaaatt
    20521 gtgcaagtta gaaaatgaac taacaagaaa agttttcttt gctgaatctg attttgttag
    20581 gttaacaaat atatgtagac agagatgata cttaggtatc atctgttgat ctattatgat
    20641 ttgttattag aattaaggag ttatatgaag acagtagaac atctcatcga aacatttgtg
    20701 cctgaaaatt ataacatctt tttagatatt aatcgtcaga ctaaaacatt tacggggaat
    20761 gttgcgatta atggtgaagc tttagataat catgtggctt tccaccaaaa agatttggac
    20821 attaagtcta ttttgctcga taatgaagct gttatttatc aagtggataa cgacaatgaa
    20881 gttgtgcgtg ttgaattacc tgaaacagga atgatgacgc ttgtcattga attttcaggt
    20941 agcattacag ataatatgac aggtatttac ccttcatatt acactaaaaa tggtgagaaa
    21001 aaagaagtca tttcaactca gtttgaaagc cattttgcac gtgaagcttt cccatgtatc
    21061 gatgaaccac aagcaaaagc tacttttgat ttaagcttga cctttgatca agaaattggt
    21121 gagatagcgt tatcgaatat gccagaagtc aatattgacc gtcgcgagga gactggtctt
    21181 tggacatttg atacgacact aagaatgtca tcttacttgc tagcgtttgc gctaggagaa
    21241 cttcatggaa agactgtaga aagcaaaaaa ggaacaactg ttggtgtgta tgcgacaaca
    21301 gcgcatcctc ttagctcgct tgatttttca ttggatattg cagttcgtgt tatcaacttt
    21361 tatgaagact attttggagt acattaccca atcccgcaat ctcttaatat tgcgcttcca
    21421 gatttttcat ctggtgctat ggaaaattgg ggtttaatca cttatcgtga aatttattta
    21481 ttagtagatg aaaattcgac tgttcaaagc cgacaacaag ttgcacttgt aatcgcccac
    21541 gagatagcac accaatggtt tggaaacttg gttacaatga aatggtggga cgatctgtgg
    21601 ttaaatgaga gttttgccaa catgatggaa tatgtctcta tcgaggctat tgagccgtct
    21661 tggaaaataa tagaagattt ccaaacaggc ggtattcctc ttgctttaaa acgtgatgct
    21721 actgatggtg ttcaatcagt gcatgttgaa gtcaatcatc cagatgagat aaatacattg
    21781 tttgatcctg ctattgtcta tgcaaaaggt agtcgtttga tgcatatgtt acgccgtttt
    21841 attggtgatc gtgattttgc cattggctta catcactact ttgaaaaata tcaatatcga
    21901 aatactgtcg ggcgtgattt atggaatatt ttatcagata cttcaggcaa agacgtagct
    21961 gcttttatgg atgcttggct tgaacaacca ggttatccag ttttaacagc tcgccttgaa
    22021 aacgatcaat tgattttgag tcaaaaacaa ttttttattg gaaaaggtga agaaaaaggt
    22081 cgcctttggc cgattccttt aaacactaat tggcatggcc ttcctgaaac tttgacagag
    22141 gcagaaatgg tcattccaaa ctttagtcaa ttggcagcag aaaatgaagg agctctacgt
    22201 ttcaatattg ataatacagc tcattacatt acagactacc aaggatcatt attagatgcc
    22261 ttagtcactg aacttgccca acttgataat acttctgctt tacaagttat tcaagaacgt
    22321 cgtttattgg cagatagtgg cttgatttcc tatgctgaat tggttgactt aattgctcaa
    22381 ttggacgatt ctaagtctta tatggtagca gaagcggttc aacaagtggt ctctggtttg
    22441 aaacgcttca ttgatgaagg aagcttagca gaaaaatcct ttaatcgctt ggtaaccacc
    22501 atctatcaag aagactttaa tcagcatggt tttgagaaaa aagctgacga atcagatgaa
    22561 gatgagatgg tacgtcaggt tgccttgggc cgcttgtggc tagcagaaaa tcagacgatt
    22621 attgacggat tgagaactat ttttgaagca tatcaaaaca atattgcaag tattccagca
    22681 gctgttcgtc gcttggtttt agccaaccaa atgaaatatt ttgaaacaga tagcttggtt
    22741 gatatttatt ttgagactta tgtagcaact actgataata atttacgcag tgatttaacg
    22801 gttgctttta gtcaaacaaa acaaccaact actattagac gtattcttgt tagtttaaaa
    22861 gataaagata ttattaaacc tcaggattta tcttattggt acaatgcttt gcttggacaa
    22921 agctttactc aagatatcat ttgggaatgg gctagagaaa attgggattg gattaaatct
    22981 gcacttggtg gagatatgag ctttgataaa tttgttattt atccagcaag taactttaaa
    23041 acaccaaaac atctagcaga atataaatct ttctttgaac ctaagctaga tgatatggct
    23101 attagccgta atattaccat gggaattaat gaaattgaag cacgtgttgc tttgattact
    23161 aaagaaaaag aagcagttat tgcagctctc agtcattact agaccataag caaaagagtt
    23221 gggggacttt ccagctcttt tttgtagtga gctagcttcc tttcttagtt ccgtctataa
    23281 ctaaatgatt atccatagtt taattcaaaa ggagattgca ctttaaagcg aaggctatta
    23341 gcctcttaaa tactttttta ccaggtggtg aataagaaca attataaatg atttaatcat
    23401 tatgctttaa atgccttaaa ggagtattaa tattttagta aaccttaagc tttttgtagt
    23461 atagtctcgt tagaaattgt tatcagaaat gagactaagt taaatgaagt gatagttact
    23521 ttatttaaga acaattgagg tagagacatg ataaaaatat tattagtaga agatgacttg
    23581 agcttatcaa attccatttt tgatttttta gatgattttg cagacgtcat gcaagttttt
    23641 gatggcgatg aaggtttata cgaagcagaa agtggtattt atgatttgat tttgttagac
    23701 cttatgttgc cggagaaaaa tggctttcaa gtcttaaaag aattgcgaga aaaagatatt
    23761 aaaattcctg tattgatcat gacagctaaa gagggtttag atgataaagg ccacggattt
    23821 gaattaggtg ctgatgatta tctgacaaag ccgttctatt tagaagagtt aaaaatgcga
    23881 attcaagcac tgttaaaaag aacagggaaa tttgcagata aaaatattag ttttggcaat
    23941 ttagtggttg acttagctcg aaaagaggtg aaggttgaag ggaaagtagt tgaattactt
    24001 ggcaaagaat ttgatttgtt ggtgtatctt ttgcaaaatc aaaacgttat tttaccaaag
    24061 acacaaattt ttgatcgttt atggggattc gatagtgata ctacgatttc ggttgttgaa
    24121 gtttacattt ctaaaataag gaaaaaatta aaaggtacct gttttgttaa caggcttcaa
    24181 actttaagaa gcgtaggata tattctaaaa aacaatgaat aaattaaaaa aagagatttt
    24241 atcagataac tataaccact tttttcattt ttttgcggtt tttacaggta tttttgtcat
    24301 tatgactatt attatcttac agattatgcg gtttggcgtt tattcgtcag ttgacagtag
    24361 tttagtttct gttagtaata atgcaagtag ctatgctaat cgtacgatgg ctagaatatc
    24421 ttctttttac tttgatactg aaaataacat tattaaggcg ctgcctgatt cagatagttc
    24481 taagttatta ggaacgcctg cagctaatac agatatcatt ttgtttagtg ctaatggaac
    24541 aattttaaat gcttttgatg cgttttctaa ctatcaaaat tttcatttag ataaacgccg
    24601 gttggggagt attgaaacca ccagtttaat gaatttttat ggacaagaag aaaaatacca
    24661 tacgataact gtaggggttc atatcaaaaa ttatcctgca gttgcctata tgatggcagt
    24721 agtaaatgtg gaacaattag accgcgctaa tgaacgttat gagcgcatta ttattatagt
    24781 tatgagtgtt ttttggctaa tttctatttt agcaagtatt tatttagcca agtggagcag
    24841 aaaacctatt ttagaaagct atgaaaaaca aaaaatgttt gttgaaaatg ctagtcatga
    24901 attaaggacc cctttggcgg tcttacagaa tcgtctggaa tcgctttttc gtaagcccaa
    24961 cgaaacgata ttagaaaata gtgagcatct cgcttctagt ttagacgagg ttcgcaacat
    25021 gcgcatctta acaactaatt tattaaattt agcaagacga gatgatggca ttaatccaca
    25081 gtggactcat ttagatacag atttttttaa tgctattttt gagaattatg aactagttgc
    25141 taaagaatat ggaaaaatat tttattttca gaacc
//
LOCUS       DAUGJR010000028        24247 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUGJR010000028 DAUGJR010000000
VERSION     DAUGJR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24247
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.028"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..180
                     /locus_tag="VH800_001174"
     CDS             <1..180
                     /locus_tag="VH800_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEQ8362248.1"
                     /translation="DSLTRQVKNIYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEW
                     IGDAIVHVESKLNAR"
     gene            183..707
                     /locus_tag="VH800_001175"
     CDS             183..707
                     /locus_tag="VH800_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEQ8362249.1"
                     /translation="MNIEEAKRAIRELEAFNYFDFKGNLIKRIDVLGIIDQLGQPKVV
                     VPKPVFEMIKFRKEHDQDLTTTFVNIHAYPDNVFHWVANNGDLFAQAWLAYPNITIEK
                     EKLYTVEIPNPNREGRGHAKFVLERQGNKVFLVKRKSKDCYYNKNSNHLTESEIRKDF
                     DWAWREGFAEEVTE"
     gene            704..970
                     /locus_tag="VH800_001176"
     CDS             704..970
                     /locus_tag="VH800_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362250.1"
                     /translation="MKEKTIFISKKYANDFNNDKYNLSSGYYFKNGEQHDIAIVKYGE
                     QDYLKNTDLAYVVCDKIVDGESIGFVYHGEYETWRFKLLNTEAN"
     gene            1256..1690
                     /locus_tag="VH800_001177"
     CDS             1256..1690
                     /locus_tag="VH800_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEQ8362251.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPYGTPSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLAPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGVLLAEKGVFS"
     gene            2300..2680
                     /locus_tag="VH800_001178"
     CDS             2300..2680
                     /locus_tag="VH800_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362252.1"
                     /translation="MARANKAKMLDAIEFKLLNPTANQAQVAEIIGITDRQLRNWEND
                     PEDKSGWNKLNDEIAEKAFGKYALSAIGTLVNLSKNAKSELVRLQASQDILDRAGYKP
                     TDKQEISIDEPIVLANSWVQDNGS"
     gene            2670..3944
                     /locus_tag="VH800_001179"
     CDS             2670..3944
                     /locus_tag="VH800_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8362253.1"
                     /translation="MVVDLADIIPIGFKPVVQATWNPQILNIACKGGRGSGKSSNIAF
                     IISRLIIQYPVNAVCIRKTDNTLEQSVYEQIKWAISEQGLERYFKFNKSPLRITYIPR
                     GNYIVFRGAQNPERIKSLKDSRFPFAIGWIEELAEFKTEDEVKTITNSLLRGELGDGL
                     FYKFFYTYNPPKRKQSWVNKKYESQFQPSNTFVHASTYKDNPFIAKEFIAEAEATRER
                     SERRYRWEYLGEAIGSGVVPFDNLRFERITDEQVADFDNIRNGIDYGYATDPLAFVRW
                     HYDKKKNGIYAIDEYYGQKISNRQLAKWLTTKGYQSDEMFAESAEPKSNAELKNEFGI
                     KRIKGVKKGPDSVEFGERWLDDLDFICIDPKRTPNIAREFENIDYQVDRDGNPKPRLE
                     DKDNHAIDATRYAMSDDMRATKTIVKTFKGGI"
     gene            3944..5269
                     /locus_tag="VH800_001180"
     CDS             3944..5269
                     /locus_tag="VH800_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8362254.1"
                     /translation="MPELFIVPSDTEMTKDLLSELIQKHRSFNLSYSAYKQLYEGDHA
                     ILQQKQKEQYKPDNRLVVNFAKYIVDTFNGYFIGVPVQTSHENKQVSNYLELLDGYND
                     QDDNNAELSKICSIYGHGYELVFNDENAEVGITYLTPLEGFIVYDDSIRQKPLFAVRY
                     FYNKDGVLEGSYSDASKITYFKDGEKDLEIGESDPHPFDGVPMIEYVENEERQSLLAS
                     VVTLINAFNKAISEKANDVEYFADAYLKILGAELDDETLKSLRDTRIINLKDTDAQQL
                     TVEFLQKPDADATQEHLLDRLENLIFRTAMVANISDESFGTASGIALRYRLQAMDNLA
                     KTKERKFMSGMNRRYKLIASYPTSKIGPKDWIGIKYKFTRNLPANLLEESQIAGNLAG
                     IVSEETQVGVLSIVENPQKEIEKKNSDRPTLISRKAGGLNGQDTTTVLE"
     gene            5238..6146
                     /locus_tag="VH800_001181"
     CDS             5238..6146
                     /locus_tag="VH800_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ8362255.1"
                     /translation="MAKTPQQYWNERQKQLWANLETSERALQTKLSKYYADEAKSLEK
                     EIGAYFSKYGKDNVIEYRNLLQQLSKADKDLLYRDCERFAKKYPQRADLMPVRTSIYK
                     LDRLQGLELSIKIQQLEIGAIEEAELTKHLTTAFKKGYQETAKTIGFQADKVSAELFV
                     NNDWTGKGDFSSSIWSNKDKLVDYLTNDFKTAIIRGDSFDKVVKQMSERFTVRSQSDI
                     TRLIMTEGTYVNNQAMMAPFEDSDDFEEYEFVSVLDSSTSSICRGLDGHKFKLKDRQV
                     GVNFPPMHANCRSTFAMVIPDDYLER"
     gene            6153..6422
                     /locus_tag="VH800_001182"
     CDS             6153..6422
                     /locus_tag="VH800_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362256.1"
                     /translation="MNKRIKKKRKLETAIVMIVAENAMQAEALRNQNKEIMELKSIVQ
                     RNALATNEELATVKAATLDNQSAIKSIGDDVDYIKQNYKRKWRKK"
     gene            6667..7236
                     /locus_tag="VH800_001183"
     CDS             6667..7236
                     /locus_tag="VH800_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8362257.1"
                     /translation="MENEEILEQSGAQEEAKEQTFDDILSDPKKQAEFDKRVAKAIDT
                     ARNKWVAETEEKENEAKRLAKMNAEQKAQHEKAKLEARIAELEAERTLSEMKSAARTM
                     LSEANINISDALLSQLVSTDADKTKNAVEAFSEAFSEAIEKEVKERLKSPTPKKSNGN
                     TGLTKEQILAVKDTAERQKLIAENIGLFQ"
     gene            7255..8145
                     /locus_tag="VH800_001184"
     CDS             7255..8145
                     /locus_tag="VH800_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ8362258.1"
                     /translation="MVTSRTYPEENLIKSTDLKYPITIDVTNKFQENISKLLEMLGVT
                     RKISVSEGMTLKTYAGYDVTLAEGNVPEGEVIPLSKVERKIHSEKKIELKKYRKATTG
                     EDIQMYGSNEAVTNTDNALVRQLQKKIRTDFVTALKTGTGTQDALGAGLQGALASAWG
                     KLQVLFEDYGSERAIVFANSLDVAEYIAKAGITTQTAFGLTYLVDFTGTVIISTNDVT
                     KGEIWATVPENIIFAYINPNNSELAKEFNLYGDPTGYIGMNHFQENTTLTIQTLLVSG
                     MLMYPERIDGIVKVTLTPGV"
     gene            8158..8451
                     /locus_tag="VH800_001185"
     CDS             8158..8451
                     /locus_tag="VH800_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEQ8362259.1"
                     /translation="MAYRVKARFFDLLDNSFLYEVGDSFPRKGYEPSKERLESLLSSN
                     NTEHKPFIEVSGNGNSLDGLKVDELKAKAAELGIELPSNAKKAEIIELLQAHI"
     gene            8465..8809
                     /locus_tag="VH800_001186"
     CDS             8465..8809
                     /locus_tag="VH800_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362260.1"
                     /translation="MDETKQAIIDRVRVRLADETSLKEELLEELTQTAIDRINLKVGD
                     VVFNPLFNSIAVDVVVKMYRRMYFEGIDTEKADTISTKFIENVLAEYGEELASYKKDR
                     LAILNKKVVRFL"
     gene            8806..9117
                     /locus_tag="VH800_001187"
     CDS             8806..9117
                     /locus_tag="VH800_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362261.1"
                     /translation="MMFVNFDLVTSQKTGEKDRLGNDITKNVVKRVAKGRFTEWSADD
                     VSLYGRDLTSSARKLLTNQVSKAEAKQASHVVIDGSKYKVESVKDLGRWRLLVIKGYR
                     L"
     gene            9114..9509
                     /locus_tag="VH800_001188"
     CDS             9114..9509
                     /locus_tag="VH800_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362262.1"
                     /translation="MRMSMTGMPALEVKLRSMSEKRWDRVANKNLTEMFNRAARPPGT
                     PIGKNTKRHKSGELLRSRRLKKVNSSKDVITGNFGYIKDYAPHVEYGHRIVRNGKQVG
                     YANGTKYLFNNVKKQREIYRQDMLNELRR"
     gene            9511..9921
                     /locus_tag="VH800_001189"
     CDS             9511..9921
                     /locus_tag="VH800_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5072 family protein"
                     /protein_id="HEQ8362263.1"
                     /translation="MLKKLGLVDLHASIKQKIEDKTGLMAYDHVPEDMPSPFYFIEVV
                     DKRPEDTKVMWCEVFTVWIHAIAEAGKSKIAIYDMIEKLEEALTEELVLPEEIDILRQ
                     SEVGMQSLQEDETGEMHAIVAYEIKVSYGFKVKV"
     gene            9933..10439
                     /locus_tag="VH800_001190"
     CDS             9933..10439
                     /locus_tag="VH800_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8362264.1"
                     /translation="MVAFDQNVYCNFDTSATKAIAGKDIILAIFDKTGANLLAISGQQ
                     GLTINRTADSIEVSSKDTKGGWKSKIPGMKEWSIDNDGLYVPSDETHKQLGEAFEKSE
                     FVCIKVINGKTKKGMFGGLASVSDYSLEAPYDDGMTYSISLEGNGALIDLSTLSSEDA
                     EKVTAMPS"
     gene            10452..10769
                     /locus_tag="VH800_001191"
     CDS             10452..10769
                     /locus_tag="VH800_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362265.1"
                     /translation="MDKELIIIDEKQYELKYNEKTIETVEALTGKAFMDVIVNNKGML
                     SLSMLRQYFANALYAVEGGRVSSEQGSNIFTKVLNTKGYAYVNMLVINTIQRDCPFFF
                     LGA"
     gene            10742..11200
                     /locus_tag="VH800_001192"
     CDS             10742..11200
                     /locus_tag="VH800_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362266.1"
                     /translation="MPFFLPRRLVDFEYLGGSGDSTDVEYDRLASQYHKDIDFAFYFV
                     NFGTTKSEFLELTRREKAFIRKAWEDKQVRESELMRNAVLNAVSNAMRKKSAKFVDLW
                     KRQQQPANMEIVEAHLEIINKNIADEGKYWVDLVYQANNMTKPSEGAENG"
     gene            11193..12998
                     /locus_tag="VH800_001193"
     CDS             11193..12998
                     /locus_tag="VH800_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8362267.1"
                     /translation="MADYTLGVQITGDASKMQKAFEKAQEQAEKLKEKIKDSNNESGN
                     SFDGLTTKIDAISGKLSAYGDKISSIGKNMTTMFTLPAVAGITAVVKEYANLEQSIGG
                     VETLFKKSAKAVQKNANTAFRRAGVSANEYMEQVTSFSASLISSLGGDTAKAVGVADT
                     AMVDMSDNANKFGTNIGLIQNAYQGFAKGNYTMLDNLRLGFGGTKEEMQRLLDEAGKL
                     SGMEFDINNFSDIIQAIHIIQDNLGVTGTTAREASETISGSFSQAKASVIDFMGSLGG
                     DGSDVDAKMQAMIQSITVFADNVKEALGRIWDNLPLQEYQKNLLLIAVVGGPILVVVG
                     TIFGAIANIMTVVSGILTVLGMMTPIGWIIAAAIAAIVAAVVFWDDIVAEVGQKFELV
                     KIIGMAMWESFKDGVSSFGKSIQNVVGKIGGWFAEAWNAAADTATRIFTKVGDTISGI
                     FSGVVSGIKSLINGAIGGINKVIGITNKLPGVNIPKIPYLARGTSDWQGGFARINEGG
                     RGELVHMPNGATVVPHDVSMKYARESAKANSGVAYMDSNDEIAKSALKLANDAVKRPV
                     VLNINGREVAKTTGGDMRDYLNSRDMTLKRLRGEV"
     gene            12999..14483
                     /locus_tag="VH800_001194"
     CDS             12999..14483
                     /locus_tag="VH800_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEQ8362268.1"
                     /translation="MATMTFNDVDLSSLITIMSINRDIGNERQADTNDAPFIGLHIKK
                     IKTSAKIITVDFYLKDRTNEYALNQLKHKLAGIFNVNEQVKVTFSDEPDKYYLAIPIN
                     KISASDPIAWLSLVSLELLVPDGVAHSVSYKKITNYRQDGKKLLIDITNNGNVDAHPI
                     ITVKHNAENGYLAFVNKSSVFEVGDREIADAEIREKSVVAYDFKDERIVNALTAGKKN
                     VAILNDSTQVLDKNLLLNTVWGRKHLELEGSVAPSGNHAGTLTFDIPDGGSLYDYLWW
                     RQIFWVGTVSQLGFIKIMVSDENGHFLYGVETIKRTLGTKTEYNFLVTNGKGGYKITD
                     LRWTFDATHFETQNPFNEPRGWSDMTRADDTVSVFWWGSQNKRVFPELKGKKSKQVHI
                     AIGTIQGSPLVTHMYIDGFYYRKDKVPYEFNIPNAFGAGTEVVINAENDTVLVDNIPK
                     ANIIADGFFSFPKIPPGTSTLEVYSSSWSTANPDITLNFEERWL"
     gene            14484..17924
                     /locus_tag="VH800_001195"
     CDS             14484..17924
                     /locus_tag="VH800_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8362269.1"
                     /translation="MLITIHNANLEKVAYIDNDKQDTLNYYDDKFSQYLNTANSTFEF
                     TVYKRGIKSDTVKEKAYLTLTERSFVSFKYNGKSYLFNVMTTDETDIEIRCYCENLNL
                     ELLNEYAGPYKAATQMSFVDYCNLFGILKNGAITIGTNETTDQKRTIEWTGQDTNLKR
                     LLSIANNFDAEIEFVTHLKNDSSLKSFVMNVYKKNDATNQGVGRRRDDIILQYGKNIE
                     SVRRKINKTGIYNAIRPSGKITTTTTTTTAKQGSVQTGSVLWSGGNLTYAGHVMQSSV
                     VNTILSLCSKYKLLPSGVFSQLYLESFWGDTPVGRADNNWGGITWTGATTRPSGINVS
                     QGQSRAEGGYYNHYASVDDYLKDYAYLLAEQGIYAVKGKLTIDEYTRGLFRVGGATYD
                     YAAAGYDHYAPLMRDIRAGINRNNNGAMDNVDNQFKNGGSTSQNTTQIAAKTKAVLAE
                     ANGLKGQRVGSGQCYALAAWYAMKLDGPGLNGGVTSFRGLIGAGAAAAQIGTDYNWGQ
                     FGWKVVQPNKVADLITGSIVNIRANAGSPVFTGAWGHTVVVKSLSGDTLTVLEQNYNN
                     VQTVQEHTYSASAYLSVVQTVCYPPEIVQGKRVEGTAQAEQPQSETTTISEEKEVLIN
                     PSLYREWKNEAGQVEFYVKNSMLYAPLSKSLYPSAFTGIETDDNWIRKDLDVDTESEE
                     KLISVALADLRKHCYPAVTYEVSGFIGDLDIGDTIKINDPEYTPSLILEARVSEQHIS
                     FTEPNQNKTVFDNYRALESKVSQGLIDRMNELAEAAKPYDLRLMTDNGNVFLNGEGRT
                     ILTAELWKGNKKFDASYQFKRDGQLVGAGLQLAVDAKDVPADRPLIITVEAYLNNELI
                     ASKQITFTNSLGEQGPAGRGIVSTEDYYLASPNRTGVTSATSGWTKTPQEITETNKYH
                     WYYHVDVYSDGTRKETTPAIIGVYGDKGSDGKQGKRGEMGPSGPPGALDKKQLQDINN
                     KIDGKADQNLTIEQINKLAELQSIANAELQAKASIDALASLQKQVQSAIAAMNASQKL
                     SEQDLITASQRAIKATNDILDLKEQWNFIDNYMSASEEGLIIGSKDGTSSVRVAKDRI
                     AFYSAGAEVASITGGMLKIDNGMFVATLQVGHFREEMYKVDGVDKHINVTRYYETIVG
                     "
     gene            17929..19791
                     /locus_tag="VH800_001196"
     CDS             17929..19791
                     /locus_tag="VH800_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362270.1"
                     /translation="MAEFWSNNDRGYRIKLTIDQVSQNTLANSSQVRVKLDLLNTTTT
                     FTQYSCSAYVDLNGQRIDWSDSPSVLRYNSTISLIDRTITVNHNADGTKSFGFIASFS
                     GSGGWSPGTLTVGSGTFTLTTIPRSSSVVVSSGTIGSAITININRQSSSFKHNLRYQW
                     GNKTGTIASDVDTSAVWTIPLDFASDIPNSTSGSGTIYVDTYNDSTLTGTQQVPFTVT
                     VPDSMKPTLSSISLSDAHTVAGNVVSSADYFIQVYSDIRVNFESASGSYGSTIKGYYA
                     EIVDKGQSTDQNGGTLGNMLYDGQITIRAKVIDSRGRESQPMDKTVTVLKYFPPALSF
                     DVARSGYGSDTLTVTRRASIAPLSVFGTQKNTMTLSFSVAELGSSYFSANNGSASGAW
                     ANVSSLVNSSANLYGAFSPTKSYTVKGILSDKFSRTEFTFDVGTESVVMSIAKNGIGF
                     QKIWEKGAIDAKGDAYISGKLFVNNTEVKPSFDKTEILNMVYPVGAIYMSTSSANPST
                     FIGGTWQRYAQGRTIVGVSENETEFNYVGKTGGAKTHTLTNEEMPSHSHGDKTISSGG
                     RPISSNAGWDNTNVGLYKSTDYNQINAFNKSSGGDQPHNNLQPYITTYIWLRTA"
     gene            19802..20149
                     /locus_tag="VH800_001197"
     CDS             19802..20149
                     /locus_tag="VH800_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8362271.1"
                     /translation="MLVITSNYPEQMPDGSVSGAKVMLDGIDDHAGWHIPLTLLKEYL
                     DKPQSEVMTLCEKMIYQQLKPQKALNEKFAKLDATIEKGENMLKFATGILNQIIAAKE
                     EETTDDETVEKMD"
     gene            20299..20622
                     /locus_tag="VH800_001198"
     CDS             20299..20622
                     /locus_tag="VH800_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362272.1"
                     /translation="MTIDVTLFAQWCVALTAIIVFLKWVSAPVKHVLDNNKKAMEALE
                     SAIVKISDDLKDNNFKWTESKNHRDRLQKVQDQHEIRIGIVEDRLISHDEQLKTLWKV
                     KEEKK"
     gene            20622..20954
                     /locus_tag="VH800_001199"
     CDS             20622..20954
                     /locus_tag="VH800_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEQ8362273.1"
                     /translation="MEELIQVITGSALSILTIFAGIVVKLVKDYLLKKGGEKAVKIAE
                     IVARNAVEAVEQIAYDKDIKGIEKLTEAKIAVRDELSKHNVYLSDKQMEVFIEAAVKR
                     MNDSWKGQ"
     gene            20956..21720
                     /locus_tag="VH800_001200"
     CDS             20956..21720
                     /locus_tag="VH800_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8362274.1"
                     /translation="MATVSEVISYWRGLADTGQGYDADLAWGWQCADVTNGTTTNFFG
                     VTLWGNAIDLLDSAKAQGLEVIYDAPGINPKAGDLFVMFTYGHPYGHTGIIIADSDGY
                     TIQTIEQNVDGYSDNNGDGINDQFQVGGPARYVTRAFSDGDGYIVGWIRPPYSDTSSE
                     KQSQSQAPSGFRKLKDEVGTFEVMVPALNVRREPSLNGEIVACYQYGMTGTYDSVYVG
                     DGYIWVSYVGASGMRNYMAVGDADGDYNVNPYCKFY"
     gene            21732..22334
                     /locus_tag="VH800_001201"
     CDS             21732..22334
                     /locus_tag="VH800_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362275.1"
                     /translation="MGYNSTNLKQVDGGDVIKQGDTSSLFSFNLLDENNNVIDLNGKQ
                     ATIYFTRNRKTYLTKTTDVIDNKVDFTINKILEIGTYYIEVHCDGYVFPSDDSVTLDV
                     RRSGQKYVVSTDLITDTTIQKLSADIEYLKSKVTQNQHLFEQVSPQTEWTITHNLIKY
                     PSVTIVDSAGNEVFGSVEYISTTKIIVRFSAPFAGKAILN"
     gene            22345..23118
                     /locus_tag="VH800_001202"
     CDS             22345..23118
                     /locus_tag="VH800_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362276.1"
                     /translation="MSTFLTNINLNKNELQNAVVQNLAKEPHEPKSGQFYFDSAANNL
                     KIYNGTSWVVLDKETAESIVDLINSGKSKIDKSKVDGLEEAINQASMTGQAIATALNE
                     DTGGVTVNQNKITGLTDKLAEIATNKASATRESQDALQEAKVYADQKVAGLVDSASED
                     YNTFKELETFIKQNAKGLAAISNVAKKFSKTFGDARAKEFTITHNLKTRDVNVTIRET
                     NFPYAIVYADIKVTDENSILIATGAEVLTQNQYTVTITG"
     gene            23128..23349
                     /locus_tag="VH800_001203"
     CDS             23128..23349
                     /locus_tag="VH800_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362277.1"
                     /translation="MRYIGESQLSKDLVTKDYVDNKVTNLASKDDIVNLGKIKDSQTG
                     AFLEVKIVPNGQVPYDTTGMIVFERSGGK"
     gene            23349..24008
                     /locus_tag="VH800_001204"
     CDS             23349..24008
                     /locus_tag="VH800_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362278.1"
                     /translation="MSVQEIPDKIFYRLIEQTVEAKLVWDKDTQIGSYYISIHDKYSF
                     ESGRDVNIYKILSSTQADVYKANKYNYQSSSKPDTSVPQPKPPEQPPLKNKSLYQSIT
                     IDGLPIARVICNNQVIWSQSAEPQEVYNITAYVDASVSKLNDSAIIDYNRDFAAYGVN
                     WSRVDRVAVEVDDKIVAKLQAPVYDFGVRGGTTMSVEKWDYPSNTIDKYKNPTFKILQ
                     H"
     gene            complement(24130..>24247)
                     /locus_tag="VH800_001205"
     CDS             complement(24130..>24247)
                     /locus_tag="VH800_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8362279.1"
                     /translation="FDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK"
BASE COUNT         8119 a         4306 c         5289 g         6533 t
ORIGIN      
        1 gactctttaa caagacaagt taaaaacatt tattttttgc aaaatacaaa agacgacatg
       61 ctgagtttta gtgatattaa cgttatgcca agaactcaag atattgagcg agaatttaat
      121 gtcaaagagt ggattggtga tgcgatagtg catgtagaga gtaagttaaa tgcgaggtaa
      181 aaatgaacat tgaagaagcg aaaagagcga taagagaact agaggcgttt aattatttcg
      241 attttaaagg taatttaatt aaacgaattg atgtattagg tatcatcgac caactcggcc
      301 aaccaaaagt ggtagtgccg aagccggtat ttgaaatgat taagtttaga aaagaacacg
      361 accaggattt aacaacaact tttgttaata tacatgctta tccagacaat gttttccatt
      421 gggtggcaaa taacggtgat ttatttgccc aagcatggct agcttatcca aatatcacca
      481 tcgaaaaaga gaagctatat acagtggaga taccaaatcc gaacagggaa ggcagaggtc
      541 atgccaagtt tgtgcttgaa agacaaggta ataaagtttt tttggtaaaa cgaaaatcaa
      601 aggattgcta ctacaataaa aacagcaatc acctcactga atccgaaatt cgtaaagatt
      661 tcgactgggc atggcgagaa ggatttgcgg aggaggtgac ggaatgaaag aaaaaacaat
      721 ttttatatca aaaaaatatg caaatgactt taacaatgac aaatataatt tgtcctctgg
      781 ctattatttt aaaaatggtg aacaacatga tattgctatt gttaaatatg gcgaacaaga
      841 ttatttaaaa aatactgatt tagcatatgt tgtatgcgat aaaatcgttg atggagaatc
      901 tataggcttc gtttatcacg gcgaatatga aacttggcgt tttaaactat taaacacgga
      961 agcaaattaa attcccgcgc aagcgctcaa gagcctgcga tggctctgtg ggggtggacc
     1021 gaaattaaaa aatagaaacg agaacctcct tacaccaaaa caaatctaaa gcgggttatc
     1081 ggtcatccgt gattatccaa ggcgtcgcta atgctttaac acgacatcgt gcgcctgtgt
     1141 caaaaaacaa aggaaagaga ggacttttct ccacaaaaca aaaagacgtc catacggaac
     1201 gcccccttgg ttaaatttaa gcttaaataa attataccac attggggggg ctttcatgac
     1261 gttttttcca gagattgata tccaaaaaac aaaatctaat gccaagcgta aattgagaga
     1321 gtatccacgt tggcgaagga tagctaatga tgtagatact caaaaagtga cagccactta
     1381 ttcctttgag ccaagacaac cgtatggaac gccaagcaag cctgttgaga gactagcgct
     1441 caaccgcgtg tcagcagaac aagagctgga tgcgattgag caagccgtca gtatgatact
     1501 agagccagag agacgcagga ttttgtatga caaatactta gcgccttata aaaaggcaga
     1561 taaggttatt tatacagaat tgtgtatgtc agagagcttt tactatgata cacttgacat
     1621 tgctttgtta gcttttgcag agctgtacag agagggtgtg ttgcttgctg agaaaggagt
     1681 ttttagctag tttttataca gtaataagat agtttataca tatttttaca tgttattata
     1741 gtattatcaa aataacaaga agagataacc ttttaatcac tgactatttt atttagtcgc
     1801 caactttaac tacaatcaaa cttgttattt tgtagcctga tggcggtaca gcgagttgag
     1861 acgacaactg ggtatgcagg ttcgattcct gccgtctcaa tcagcgccca gaagaggcgc
     1921 gacccagtat cccgaaaggc agtcacgcac tgatatactg gtttttactt ggttgatagt
     1981 catattccta ccaatgacga ttgataaaaa agatacatag atcggctgta tagtctacgt
     2041 gtacgtattc acaacagatt gactcatttg attaaccgca agtaaaacaa gggtcgcaac
     2101 cttgcctgtg gttagtaggc ttaatggtcg tttatgcacg ttcgattcgt gcaaagcctg
     2161 tttgataaat agaagtgtcc cagaatgggg taggcaatag gcttagcatt catttgctat
     2221 ttatctatgg ttaaccaatt agtcatcaca ttgtggtgac ttttttattt ccgaaaattt
     2281 ccgaaaggag gaacatattt tggcaagagc aaataaggca aaaatgcttg atgctattga
     2341 gtttaaatta ttaaatccaa ccgctaatca agcacaagtt gcggaaataa tcggtatcac
     2401 agacagacag ctacgaaatt gggaaaatga cccagaagat aaatcgggtt ggaataaatt
     2461 aaacgatgaa atcgcagaaa aagcttttgg caaatatgct ctttctgcga ttggaacgct
     2521 tgttaatcta agcaaaaacg caaaatcaga attggtaaga ctacaagctt ctcaagatat
     2581 ccttgaccga gcaggttata aaccgacaga caagcaggaa atcagcatag acgagcctat
     2641 cgtacttgct aattcatggg tgcaagacaa tggtagttga tttagctgat attatcccaa
     2701 ttggttttaa gcctgtcgtg caagcgactt ggaatcctca aatactaaat atcgcttgca
     2761 aaggcggacg tggttctggt aaatcatcta atattgcttt tattatctcg aggttaataa
     2821 tacagtatcc tgtcaatgcg gtttgtatcc gtaaaacaga taatactctg gagcagtctg
     2881 tttatgagca aattaaatgg gctatatctg agcaagggct agagcgttac tttaaattta
     2941 acaaatcacc tctaaggata acgtacatcc ctagaggtaa ttacattgtc tttagaggag
     3001 cacaaaatcc tgaacgtatc aagtccttaa aagatagtcg ttttcctttt gctatcggtt
     3061 ggatcgagga gcttgcggaa tttaaaaccg aggacgaagt caaaactatc actaactccc
     3121 tattgcgtgg ggaactcggt gatggtcttt tttataaatt tttttataca tacaatccac
     3181 ctaaacgtaa acagtcttgg gttaacaaaa aatatgagag ccaatttcag ccgtctaata
     3241 cgtttgtaca cgcatctacg tataaagata atccttttat tgccaaagag tttatagccg
     3301 aggcagaagc cacgagagag cgttcagaac gtcgttatcg ttgggagtat ttaggagagg
     3361 ccattggttc gggtgttgtt ccatttgaca acttacgctt cgaacgtatt actgacgaac
     3421 aagtagccga tttcgataat atccgtaacg gtattgacta tggttatgca actgacccgc
     3481 ttgcttttgt acgttggcat tatgataaaa agaaaaatgg tatctatgct attgacgagt
     3541 attatggtca gaagatatca aacaggcagc tggctaagtg gttgacgact aaaggatatc
     3601 agagtgatga gatgtttgct gaaagtgctg agcctaaaag taatgctgag cttaaaaacg
     3661 agtttggcat caaacggata aaaggcgtta aaaaaggacc agattctgtc gagtttgggg
     3721 agcgctggtt agatgactta gattttatct gtatagaccc aaaacggaca ccaaatatcg
     3781 ctcgagagtt tgaaaatatc gactatcaag tcgatagaga tggcaaccct aaacctcgtt
     3841 tagaagacaa ggataaccat gcgatagatg cgacaaggta tgctatgtca gacgacatga
     3901 gagcgactaa aaccatcgtc aaaacattta aaggaggtat ctagtgccag aattatttat
     3961 tgtgccatca gatacagaga tgacaaaaga tttgttaagc gagttaatcc aaaaacacag
     4021 gtcgtttaac cttagttatt cagcgtataa gcagctatat gagggtgatc atgctatttt
     4081 gcaacaaaaa caaaaagagc aatacaagcc tgataatcgc ttggttgtta attttgcaaa
     4141 atacatcgtt gatacattta acggctattt tatcggtgtg ccagtccaaa cgagccacga
     4201 gaataaacaa gtcagcaatt atttagagtt attagacgga tacaatgatc aagacgataa
     4261 caacgcagaa ctatcaaaga tttgcagtat ttacggacat ggctatgaat tagtttttaa
     4321 tgacgagaat gcagaggttg gaattactta tctgacgcct cttgaaggat ttattgtcta
     4381 tgacgactct attagacaaa agccgttatt tgctgtgcgc tatttttata ataaggacgg
     4441 tgttttagag gggtcttatt cagacgccag caaaatcact tattttaaag atggcgaaaa
     4501 agaccttgaa atcggggaga gcgatccaca tccgtttgat ggtgtgccaa tgattgagta
     4561 tgtcgaaaac gaagagcggc aaagcttgct agctagcgtt gtgacattaa ttaatgcgtt
     4621 taataaagct atctccgaaa aagccaatga cgttgagtat ttcgcagacg cttatcttaa
     4681 aattttgggt gctgagctag acgacgagac attaaagtct cttagagaca cccgcattat
     4741 caatctaaaa gacaccgatg cacagcaatt aactgttgag tttttacaaa agccagatgc
     4801 cgatgcaacg caagagcatt tgctcgaccg actagagaac ttaattttta ggactgctat
     4861 ggttgctaat atcagtgacg aatcgttcgg tacagctagc ggcatcgctt tacgttatcg
     4921 tttgcaagct atggataact tagctaagac aaaagagcgt aagtttatga gcgggatgaa
     4981 ccgcagatat aagcttattg caagctatcc tacgtctaag ataggaccta aagattggat
     5041 tggcattaag tataaattta ctcgcaatct accagcaaat ctcttagagg agtctcaaat
     5101 tgcaggcaat ttagcgggga ttgtctcgga agaaacacag gtcggtgtgc tatctattgt
     5161 ggaaaaccca caaaaagaaa tcgaaaagaa aaatagcgac aggccaacct taattagtcg
     5221 aaaagcagga gggctaaatg gccaagacac cacaacagta ttggaatgag cgccagaagc
     5281 aactatgggc taatttagag acgtcagagc gcgctttaca gactaagctt agcaaatatt
     5341 acgctgatga agcaaagtcc ttagaaaagg aaataggggc ttattttagc aagtatggaa
     5401 aagacaacgt tattgaatat cgaaatcttt tgcagcagtt atctaaagct gataaagact
     5461 tgctttatcg agattgtgag cgatttgcta aaaaatatcc acaacgtgct gatttaatgc
     5521 ctgtcaggac ctctatttat aaattagata gactgcaagg actagaatta agcattaaaa
     5581 tacaacagtt ggaaataggt gctatcgaag aggcggaatt gactaagcat ttaacgacag
     5641 cctttaaaaa aggttatcaa gaaaccgcta aaacaattgg tttccaagcg gataaagtat
     5701 ccgctgagct gtttgttaac aatgattgga caggcaaagg tgattttagc tcaagtattt
     5761 ggtctaacaa agataagctt gtcgattatc taacaaatga ctttaagacg gcaattatca
     5821 ggggagatag ctttgataaa gtcgttaaac agatgtcaga gcgttttact gtacgttcgc
     5881 agtcggatat tacacggctg atcatgacag aagggactta tgtcaataat caagcgatga
     5941 tggcaccgtt tgaggatagt gacgactttg aggagtacga atttgtctcg gttttagata
     6001 gctctactag ctcaatttgc agaggattag acggtcataa atttaaactt aaagatagac
     6061 aggttggggt taacttcccg cccatgcacg ctaactgtcg cagcacattt gctatggtta
     6121 ttccagatga ttatttagag aggtaaaaat ggatgaataa acgcattaag aaaaaacgta
     6181 aattagaaac agctattgtg atgattgttg cagagaacgc catgcaagca gaagcactca
     6241 ggaatcaaaa caaagaaatc atggagttaa aatcaatcgt tcaacgaaac gctctggcaa
     6301 caaacgaaga gttagcgact gttaaagctg ctactttaga taaccaatca gccatcaagt
     6361 caatcggcga tgatgttgac tacatcaagc aaaattacaa acggaagtgg aggaagaaat
     6421 aatatggtgt tagagcaagc tgaactagaa atggttagaa atcaacgtct ggttatgatt
     6481 aaccctgaaa tggtaactat cacaaaaaca gaatatgatc tgttgattga aataaaaaac
     6541 aaatttttag agtcgtagca atacggcttt ttattatgtc ctgtcgcatg acaaaaaact
     6601 aggcaaataa aaatctaaag caatgcgctg gggcttttga gcaatggcgt ggggcaggag
     6661 gaaaaaatgg aaaacgaaga aatcctagaa caatctggtg cacaagaaga agctaaggag
     6721 caaacgtttg acgatatttt gtcagaccct aaaaagcaag ctgaatttga caagcgtgtg
     6781 gctaaggcta ttgatactgc acgaaataaa tgggtggctg agactgaaga aaaagaaaac
     6841 gaagctaaga gacttgcaaa aatgaatgct gaacaaaaag cacagcacga aaaagcaaaa
     6901 cttgaagcac gcattgcaga gctagaagct gaacgtacat tgtcagaaat gaagagtgct
     6961 gctcgcacaa tgctatcaga agctaatatc aacatctctg acgcactttt atcgcaattg
     7021 gtatctactg atgcagataa aaccaaaaat gcagtagaag cgttttctga ggcattttcc
     7081 gaagcaatcg aaaaagaagt caaagaacgc cttaaatcgc caacacctaa aaaatcaaat
     7141 ggcaatactg gactgacaaa agaacaaatt ttagcagtca aagatactgc ggaacgacaa
     7201 aaactcattg ccgaaaatat cggcctattc caataaaaca ggagaaatta acacatggta
     7261 acatcacgta cttacccaga agaaaatcta atcaaatcaa cagaccttaa ataccctatc
     7321 actattgatg tcacaaacaa attccaagaa aatatctcga aattacttga aatgctcggg
     7381 gttactcgta aaatctcggt atctgagggt atgaccctta agacatacgc tggttatgat
     7441 gtcacattag cagaaggtaa cgtcccagaa ggcgaagtta tcccgttatc aaaagtagag
     7501 cgcaaaatac actctgagaa aaaaatcgaa cttaaaaaat atcgtaaagc aacaaccggc
     7561 gaagacatcc aaatgtatgg ctctaacgaa gctgtaacaa atactgacaa cgcacttgtt
     7621 cgtcagttgc aaaagaaaat ccgcacagac tttgtgactg ctcttaaaac aggtacagga
     7681 acacaagatg ctcttggtgc aggattgcaa ggggctttag cttctgcttg gggtaaactg
     7741 caagtgctct ttgaagatta tggttcagag cgtgcgattg tgtttgctaa tagccttgat
     7801 gtcgctgaat acatcgctaa agctggcatc actactcaaa ccgcattcgg attgacttac
     7861 cttgtcgatt ttacagggac ggtcattatc tcgacaaacg atgtcacaaa aggggaaatc
     7921 tgggcgacag taccagaaaa tatcatcttt gcttacatca atccaaataa ttctgaatta
     7981 gctaaagaat ttaatcttta cggtgatcca accggctaca ttggaatgaa tcacttccaa
     8041 gaaaatacaa cgcttactat ccaaacgttg cttgtatctg gtatgttgat gtacccagaa
     8101 cgtattgacg ggattgttaa agtaactctt acaccaggcg tctaatgggg gtagcttatg
     8161 gcttatagag taaaagcacg tttttttgat ttgcttgaca atagcttttt gtacgaggtt
     8221 ggcgacagct ttcctcgcaa aggctatgag ccaagcaaag agcgcttaga aagcttgtta
     8281 tctagcaaca atacagaaca taaaccattt attgaggtgt caggtaatgg caatagctta
     8341 gatggtttaa aagtggatga gttaaaagct aaagcggcag agctaggaat cgaactccca
     8401 agtaatgcta aaaaagctga aatcatcgaa ttactgcaag cacacatcta gaaagtaggt
     8461 tgacatggac gaaacaaaac aagcaattat tgatcgtgtc cgtgtccgtt tagcagacga
     8521 aacgtcttta aaagaggagt tattggagga gttaacgcaa acggctatcg accgtattaa
     8581 tttaaaagtc ggcgatgtcg tttttaaccc tctttttaat tccatcgctg ttgatgttgt
     8641 tgtcaaaatg tatcgtcgta tgtattttga aggaattgac acggaaaaag cagacacaat
     8701 atcaactaaa tttattgaaa acgttttggc agaatatggc gaggagttag cgtcatataa
     8761 aaaggaccgt ctagccatct tgaataaaaa ggtggtgcgg tttttatgat gtttgttaat
     8821 tttgacttag taacatcgca aaaaacggga gaaaaagaca gactcggcaa cgacatcacg
     8881 aaaaatgttg tcaaaagagt tgctaaaggt cgttttactg aatggtcggc tgatgacgtg
     8941 tccttatacg gtcgagattt aacgtctagc gcacgcaaat tgctgactaa tcaagttagc
     9001 aaggcggaag ccaaacaagc gtcacacgtt gtaatagacg gctcaaaata caaagttgaa
     9061 tccgttaaag atcttggtag atggagacta ctcgtcatta aagggtatcg cttatgagga
     9121 tgtcaatgac aggtatgcca gccttagagg taaaactaag gtcaatgagc gagaagcgct
     9181 gggatagggt tgccaacaaa aaccttacag agatgtttaa cagagcagca agacctcctg
     9241 gtacaccgat tggtaaaaac actaaaaggc ataagtctgg cgagttgttg cgctctagac
     9301 gtctcaaaaa ggtaaactca tcaaaagatg ttatcacagg taactttggt tatatcaagg
     9361 actatgcacc tcatgtcgag tatggacaca ggattgtccg caacggcaaa caggttggct
     9421 atgcaaatgg tacgaaatac ctgtttaata acgtcaaaaa acagcgtgaa atttataggc
     9481 aagacatgct aaacgaattg aggagatgac atgttaaaaa agttgggact ggttgattta
     9541 cacgcctcaa ttaaacaaaa aatcgaagat aagacagggt tgatggctta tgatcatgtc
     9601 ccagaagaca tgccatcgcc cttttatttt atcgaggttg tggataaacg gccagaagac
     9661 acaaaggtca tgtggtgcga agtgtttacg gtttggatac atgccatagc ggaagctgga
     9721 aaaagcaaaa tcgctattta tgacatgatt gaaaaactcg aagaagcgct cacagaagaa
     9781 ttagttttgc cagaagaaat cgacattttg agacaatcag aagtcggcat gcagtcctta
     9841 caagaggatg agactggcga aatgcatgca attgtagcct acgaaatcaa ggtttcgtac
     9901 ggttttaaag taaaagttta aaaggagaaa taatggtggc atttgaccaa aatgtttatt
     9961 gtaattttga cacatcagca acaaaagcta ttgcaggtaa agacattatc ttggcaatct
    10021 ttgataaaac tggtgcaaat ttacttgcta ttagtggtca gcaagggtta acaatcaacc
    10081 gtacggctga ctcaattgaa gtatcgtcta aagatacaaa gggtggatgg aaatctaaaa
    10141 tccctggcat gaaagaatgg tctatcgata atgatggtct ttacgtgccg tcagacgaga
    10201 ctcacaaaca attgggcgaa gcttttgaaa agagcgagtt tgtttgtatt aaagttatta
    10261 acggtaaaac caaaaaaggc atgtttggag ggcttgcgtc ggtaagtgat tatagcctag
    10321 aagctcctta cgatgatggt atgacatact caatcagtct cgaaggcaat ggagcattga
    10381 ttgatttatc aacattatca tcagaagatg ctgaaaaagt aacggctatg cctagttaat
    10441 gagaggaatg aatggataaa gaattaatta ttattgacga aaaacaatac gaactaaagt
    10501 acaacgaaaa aaccattgaa accgtcgaag ctttgacagg taaagcgttt atggatgtta
    10561 ttgtgaataa caaaggtatg ttgtcgctat ctatgttgcg tcagtacttt gctaacgctc
    10621 tttatgcggt agaaggcggt cgtgtgtcta gcgagcaagg ctctaatatt tttactaaag
    10681 tgttaaatac aaaaggttat gcgtatgtaa atatgctagt gatcaacaca atccagcgtg
    10741 attgcccttt tttcttcctc ggcgcttagt cgactttgag tatctcggcg ggtctggcga
    10801 tagcacagat gtagagtatg acagattagc aagtcagtat cacaaagata ttgactttgc
    10861 tttttatttt gtcaattttg ggactacaaa atccgaattt ttggaattaa ccagacgaga
    10921 aaaagccttt atcagaaaag cttgggaaga taaacaggtg cgagaaagtg agcttatgcg
    10981 caacgctgtt ctaaatgcag tcagtaacgc tatgcgcaaa aaaagcgcta aatttgttga
    11041 tttgtggaaa cgtcagcaac agcctgcgaa catggaaatc gtcgaagcgc atttggaaat
    11101 cattaataaa aacatcgctg atgaaggcaa atattgggtt gatttagtct atcaagctaa
    11161 caacatgaca aaaccgagcg agggggcaga aaatggctga ttatacttta ggagtacaaa
    11221 taacaggtga cgcctctaaa atgcaaaaag cgtttgaaaa agcgcaagaa caagctgaaa
    11281 aattaaagga aaaaattaaa gactcaaaca acgaatctgg caattctttt gatggtttga
    11341 ccactaaaat tgacgcaata tctggcaagc tgtcagctta cggagataaa ataagctcta
    11401 ttggcaaaaa catgacaacc atgtttacat taccagcggt tgctggtata acggcagttg
    11461 ttaaagagta tgcaaatctg gaacagtcaa ttggtggtgt tgagacttta tttaaaaagt
    11521 ctgccaaagc tgtgcaaaaa aatgcaaata cagcgtttag acgagctggt gtatctgcta
    11581 atgagtacat ggagcaagta actagctttt ctgctagtct aatttcatct cttggcggag
    11641 atacagcaaa ggctgtcggt gttgctgata ctgccatggt cgacatgtct gacaacgcta
    11701 ataaatttgg tacaaacatc gggttaatcc aaaatgccta tcaaggcttt gctaaaggca
    11761 attacacgat gttagataac cttagattgg gttttggtgg gacgaaagag gagatgcaaa
    11821 gattgctgga cgaagctggt aagctaagcg gcatggaatt tgacatcaat aacttttcgg
    11881 acattataca agcaatccac attatccaag ataatttagg cgtaacagga acgacagcta
    11941 gagaagcgtc agaaactatt agcggctcat tttcgcaagc aaaagcgtca gtaatcgatt
    12001 tcatgggttc tcttggcgga gatggcagtg acgtagatgc aaaaatgcaa gcaatgatac
    12061 agtcgattac tgtgtttgca gataatgtca aagaggcttt ggggcgtatt tgggacaatt
    12121 tgcctttaca agagtatcaa aaaaacctct tgcttatagc tgtcgttggc ggacctatcc
    12181 ttgttgtggt cgggactatt tttggagcta ttgctaatat catgactgtt gttagcggta
    12241 ttttaaccgt tttaggcatg atgacgccaa taggatggat catagcagca gccatagcgg
    12301 ctattgtcgc agctgtcgtt ttttgggacg atattgttgc agaggtcggc caaaaatttg
    12361 agttagtcaa aataatcggc atggcgatgt gggaaagttt taaagatggt gtatctagtt
    12421 ttggcaagtc aatccaaaat gtcgttggca aaattggcgg atggttcgcc gaagcgtgga
    12481 atgctgcagc cgacacagcc actagaattt ttactaaggt tggggatacg attagtggca
    12541 tctttagcgg cgttgtttct ggcattaaaa gtttgatcaa cggagcaatc ggtggcatca
    12601 ataaggttat tggcattacc aataaactgc ccggtgtcaa cataccaaaa atcccatatc
    12661 tcgccagagg tacatctgac tggcaaggcg gttttgctcg tattaacgag ggcggtcgtg
    12721 gagaattagt tcatatgcca aacggggcaa ccgttgtccc gcacgatgtc agcatgaaat
    12781 acgctcgaga atctgctaaa gctaattctg gtgttgctta tatggatagt aatgatgaga
    12841 ttgccaaaag tgctttgaaa ctagctaacg atgctgttaa acgccctgtt gtgttaaata
    12901 tcaacggccg tgaggtcgct aaaacgacag gcggagatat gagagattat ctaaatagtc
    12961 gagatatgac attaaaacga ttgagaggtg aggtttagat ggctacaatg acttttaatg
    13021 atgtggactt atctagcctc atcactatca tgtctattaa tcgcgacatc ggaaacgagc
    13081 gacaagcaga tactaatgat gctccgttca tcggattgca cattaaaaag attaaaacta
    13141 gcgcaaaaat cattacagtt gacttttatt taaaagacag gacaaacgag tacgcattaa
    13201 accagctaaa acataaacta gctggtattt ttaatgttaa cgagcaagtc aaagtaactt
    13261 ttagcgacga accagataaa tattatctag ctataccgat aaataaaata tcggctagcg
    13321 acccaatcgc ttggctaagc cttgtgagct tggaattact tgttcctgac ggcgtggccc
    13381 attctgtgtc atacaaaaaa atcacgaatt acagacaaga tggcaagaag ctactgattg
    13441 acattacaaa caacggtaat gttgatgcgc atccgatcat tactgttaag cacaacgccg
    13501 agaatggtta tttagctttt gtaaataaat catccgtttt cgaggtcgga gacagggaaa
    13561 tagcagacgc tgaaatccgt gaaaagtcgg tcgtcgctta tgattttaaa gacgaaagaa
    13621 tcgtcaatgc cttaacagca ggtaaaaaga atgttgctat cttaaatgac tcgacacaag
    13681 ttcttgataa aaatttatta ctaaataccg tctggggaag aaaacatctc gagttagaag
    13741 gaagtgttgc gccaagtggc aaccatgctg gaacgttaac gtttgatatt cctgacggag
    13801 gtagcttata tgactatctt tggtggagac aaattttttg ggttgggact gtttcccagc
    13861 ttggctttat caaaatcatg gtatcagacg aaaacggaca ttttttatat ggagtagaaa
    13921 ctataaaaag aacgttagga acaaaaacag agtataactt tttggtcact aatggaaaag
    13981 gtggatataa aataactgat ttacgttgga cttttgatgc tactcacttc gaaacacaaa
    14041 acccctttaa cgaacccaga ggttggtctg atatgacaag ggctgatgac actgtatctg
    14101 ttttttggtg gggttctcaa aacaagcgag tattcccaga attaaaaggc aaaaaatcta
    14161 aacaggtaca catcgcaatc ggcactattc aaggcagtcc tttagtaact cacatgtata
    14221 ttgatggatt ttattatcgc aaggacaaag taccgtacga atttaatatt ccgaatgctt
    14281 tcggggcagg aacagaagtc gttattaatg ccgaaaatga cacagtttta gttgataaca
    14341 ttccaaaagc taacatcatc gccgatggct tttttagttt tcctaaaatt cctcctggaa
    14401 catcaacatt agaggtttat tcctctagtt ggtctaccgc caacccagat attacgctaa
    14461 attttgaaga aaggtggcta taattgctta taacaatcca caacgcaaat ttagaaaaag
    14521 ttgcttatat tgataacgat aagcaagaca ccttgaatta ttatgacgac aaattttcac
    14581 agtatttaaa tacggccaat tcgacatttg agtttacggt ttataagcga ggaattaagt
    14641 ccgacacagt caaagagaaa gcctatctga cacttacaga aaggtctttt gtgtcgttta
    14701 aatataatgg caagtcttat ctgtttaacg taatgacaac agacgagaca gacatcgaga
    14761 tacgttgtta ctgcgagaac ctcaatctcg agttgctcaa tgagtatgca ggaccttata
    14821 aagcggcaac tcagatgtct tttgtcgatt attgtaattt gtttggcatc cttaaaaacg
    14881 gtgctattac cattggcact aatgagacaa ccgaccaaaa acgcacaatc gaatggactg
    14941 gtcaagatac caatcttaaa cgcttgttat ctatcgccaa taattttgat gcggaaatag
    15001 aatttgtaac gcatcttaaa aacgattcta gtcttaaatc gtttgtcatg aatgtctaca
    15061 agaagaacga cgctactaat cagggcgttg gtcgtagacg agatgatatt attttgcaat
    15121 atggcaaaaa tatcgagagt gtcagacgta agattaataa aacaggcatt tacaatgcta
    15181 taagaccaag cggtaaaata acaacgacta caaccacaac gactgctaaa caaggctctg
    15241 tgcaaacagg gtctgttttg tggtctggcg gtaacttgac ttatgcaggt catgtaatgc
    15301 aatcatctgt tgttaacact attttaagcc tatgtagcaa atacaaactt ttaccatctg
    15361 gtgtttttag ccagctatac cttgaatcgt tttggggaga taccccagtc ggaagagccg
    15421 ataataactg gggtggtatc acttggactg gcgcaacaac taggccaagc ggaataaatg
    15481 tctcccaagg gcagtctcgt gctgaaggtg gttattataa ccattacgcc agtgttgatg
    15541 actacttgaa agattacgct tacctcttgg ccgagcaagg catttatgcc gtaaaaggta
    15601 agctaaccat tgatgagtac acaagaggtc tgtttagggt cggtggcgca acatatgatt
    15661 atgctgcagc tggatatgat cattatgcac ctttgatgcg agacatcaga gcaggtatta
    15721 accgtaataa taacggcgct atggataacg tcgataacca atttaaaaat ggtggctcga
    15781 ctagtcaaaa cactactcag atagctgcta aaacaaaagc ggtacttgcg gaagcaaatg
    15841 gactgaaagg tcaacgagta ggctctggtc agtgctatgc gttagctgct tggtacgcca
    15901 tgaaattaga tggtccaggt ctgaacggtg gtgtaactag ttttagaggg cttattggtg
    15961 ctggtgctgc cgctgctcag attggtacgg attacaactg gggtcagttt ggctggaaag
    16021 ttgtacaacc gaataaagtc gcagacttaa tcacaggctc gattgttaac atcagagcaa
    16081 acgctggcag tcctgttttt acaggcgctt gggggcatac tgttgttgtt aaatctctat
    16141 ctggagatac actcacagta ttagagcaaa actataacaa cgtgcaaaca gtccaagagc
    16201 atacatatag cgctagcgct tatttatcag ttgtacagac agtctgttat ccgccagaaa
    16261 tcgttcaagg aaaacgcgtc gaaggtactg cacaagcaga acaaccgcaa tctgaaacga
    16321 ccacaatatc tgaagaaaaa gaggtcttaa ttaatccatc actttatcgt gagtggaaaa
    16381 acgaagcggg acaagtcgag ttttacgtta aaaacagtat gctctacgca cctctgtcaa
    16441 aatctcttta cccgtcagcg tttactggca tcgagacgga cgataactgg atacgaaaag
    16501 acttagatgt tgacacagag agcgaggaaa agcttatctc tgttgctctc gcagacctga
    16561 gaaaacattg ttatccagcg gtgacttatg aagtatctgg ttttattggt gatttagata
    16621 ttggtgacac tatcaaaatc aatgacccag aatatacccc aagtttaatt ttagaagcaa
    16681 gggttagcga gcaacacatc tcgtttacag agcctaatca aaataagaca gtatttgata
    16741 attacagagc tttagagagc aaagtctcac aaggtttaat tgatcgcatg aatgaactag
    16801 cagaagctgc taaaccttac gacttgcggt taatgacaga taacggaaat gtgtttttaa
    16861 atggcgaagg tcgtacgatt ttaaccgctg aactttggaa aggtaacaaa aagtttgatg
    16921 caagctatca atttaaacgt gatggtcaat tagtcggcgc tggattgcag ttggcagttg
    16981 acgctaagga tgtaccagct gatagacctc taatcattac tgttgaggct tatttaaata
    17041 atgagctgat tgcaagtaaa cagattacgt ttactaactc gcttggagaa caaggaccag
    17101 ctggacgtgg gattgtctct acagaggact attacttagc gtcaccaaat cgtacaggtg
    17161 tcacatctgc aacatctggt tggactaaga cgcctcagga aattactgag actaataaat
    17221 atcattggta ttatcacgtt gatgtttatt cagatggcac tcgaaaagag actacaccgg
    17281 ctattattgg tgtttacggc gataaaggtt cagatggcaa gcaaggcaaa cgtggggaga
    17341 tgggaccatc aggacctcct ggcgctttag ataaaaagca actacaagac atcaataata
    17401 aaattgatgg caaagcagac cagaatttga ccatcgagca aatcaataaa ttagccgagt
    17461 tacaatctat tgccaacgct gagttacaag caaaggctag catcgacgct ttagctagct
    17521 tacaaaagca agtacagtct gcaatagcgg caatgaatgc tagccaaaag ttatcagagc
    17581 aagaccttat tacagctagt caacgggcta tcaaagcaac caacgacatc ttagacttaa
    17641 aagagcaatg gaattttatt gacaattata tgtcagcgtc tgaagaggga cttattatcg
    17701 gctctaaaga cggtacaagt tccgtgcgtg ttgccaaaga ccgtattgcc ttttactcag
    17761 ctggcgcaga agtcgcttcg attactggtg gtatgctcaa aattgataat ggtatgtttg
    17821 tggctacttt gcaagttgga cattttcgcg aggagatgta caaagttgat ggggtagata
    17881 aacacataaa tgttacaaga tattacgaaa cgattgtggg gtgattaatt ggcagagttt
    17941 tggtcaaaca atgatagagg ttaccgcatc aaacttacga ttgatcaagt atcccaaaat
    18001 acattagcaa acagtagcca agtgagggtt aaacttgatt tgctaaatac aacaacaact
    18061 tttactcaat atagttgttc tgcatatgtt gacttaaacg gtcagcggat agactggtca
    18121 gactcaccat cagtacttag atataactca acaatttctc tgatcgatag aacaataaca
    18181 gttaatcata atgctgatgg tactaaatca tttggattta tcgctagctt tagcggctct
    18241 ggtggatggt ctccaggtac tttgactgtt ggtagtggta cttttacact tactaccatc
    18301 ccacgctcaa gctccgttgt tgtttcttct ggtactattg gcagtgccat cactatcaac
    18361 atcaatagac aaagctctag ttttaagcac aacttgagat accagtgggg taataaaaca
    18421 ggtactattg caagcgatgt ggatacttcc gccgtttgga ctatccctct tgattttgct
    18481 agtgacatcc caaactcaac aagtggtagc ggcactatct atgtagatac ctacaatgac
    18541 tcaacgctaa ctggtactca acaagtgcca tttaccgtaa ctgtaccaga cagtatgaag
    18601 ccaacattat caagtattag cttgagtgat gctcataccg ttgcaggcaa cgtagtatca
    18661 agtgcggatt attttatcca agtatactct gacattagag tcaattttga atcggcaagt
    18721 ggctcttatg gttcgacaat caaaggctat tatgctgaga ttgtcgataa aggacagtct
    18781 actgaccaaa acggcggaac gctaggcaac atgctttatg atggtcaaat cactatcaga
    18841 gcaaaagtta ttgatagtcg aggtcgtgaa tcgcaaccca tggataaaac agtcacggtg
    18901 ctcaagtact ttccgccagc tttgtcgttt gatgttgcaa ggtctggtta tggttctgac
    18961 acgctaacag ttacaagacg agcgtctatc gctccgttaa gtgttttcgg aacacaaaaa
    19021 aataccatga cgcttagttt tagtgttgca gaattaggtt ctagttattt ttctgctaat
    19081 aacggctctg caagtggggc atgggcaaat gtttctagtt tggtaaactc gtctgccaat
    19141 ctttatggtg ctttctcgcc gacaaagtct tataccgtca aaggtatctt gtctgacaaa
    19201 tttagtcgca cagagtttac gtttgacgtc ggaacagaat cagttgtgat gtcaatcgct
    19261 aaaaatggca tcggattcca aaaaatttgg gaaaagggtg ctattgacgc taaaggagat
    19321 gcttatatta gcggtaagtt atttgtcaat aatacagagg ttaaaccgtc gtttgacaag
    19381 acagagattt taaacatggt ttatcctgtc ggagctattt acatgagcac atcatcagcc
    19441 aatccatcaa catttatcgg cggcacttgg caaagatatg cacaaggtag gactattgtc
    19501 ggtgtctccg aaaacgagac ggaatttaac tacgttggta aaactggtgg agccaagact
    19561 catacattaa ccaatgaaga gatgccaagt cacagtcacg gggataagac tattagctcg
    19621 ggtggtagac ctatctcatc aaatgctggt tgggacaata caaatgttgg tttatataaa
    19681 tcaacagatt acaatcaaat aaacgctttt aacaagtctt ccggaggtga tcaaccacat
    19741 aacaacttac aaccatacat cacaacgtac atttggctga gaacagctta gaggagaatt
    19801 tatgttagtt atcacatcaa attacccaga acaaatgcct gatggttccg tatctggtgc
    19861 gaaggtgatg cttgacggga ttgatgatca cgctggttgg catatcccgt tgacattact
    19921 aaaagaatat ttagacaaac ctcaaagcga ggttatgaca ctttgcgaaa agatgattta
    19981 tcaacaatta aaaccacaaa aagcattaaa cgaaaagttt gctaaactcg atgcaaccat
    20041 tgaaaagggt gaaaatatgc ttaaatttgc gactggaatt ttaaatcaaa ttatcgcagc
    20101 aaaagaagag gaaacaacag atgatgaaac tgttgaaaaa atggattaaa aggagatata
    20161 tcatgatgat taattatttc gcaatgcaaa ttgagtttgg ttggattact ttggaagatg
    20221 tacctaaaaa atatcgtgac aaagtaaaac agcttgttga atcagggaat atcggaacag
    20281 aataacgaga ggccttatat gacgatagat gttacactat ttgcgcaatg gtgtgtagcg
    20341 cttactgcaa taatagtatt tttaaaatgg gtgtctgcac ctgtcaaaca cgttttagac
    20401 aataataaaa aggctatgga agccttggaa agtgctatcg tcaaaatatc tgacgactta
    20461 aaagacaaca attttaaatg gacagaatcc aaaaaccatc gtgacagact acaaaaagtc
    20521 caagatcaac acgaaatcag aatcggaatc gtagaagata gacttattag tcatgacgag
    20581 cagctaaaaa cgctctggaa agtgaaagag gaaaagaaat aatggaagaa ttaatacaag
    20641 ttatcactgg ctcagcacta tcaattttga caatctttgc aggtattgta gtcaagttag
    20701 tcaaagatta tttgcttaaa aagggcggag aaaaagcggt caaaatcgcc gaaattgtgg
    20761 ctcgcaatgc cgtggaagca gttgagcaga ttgcttatga caaagacatc aaaggcattg
    20821 aaaaactgac agaagctaaa attgcggttc gtgacgaact gtctaaacac aatgtctatt
    20881 tgtcagacaa acaaatggaa gtctttattg aagcggctgt taaacgcatg aacgacagtt
    20941 ggaaaggtca ataatatggc aacagttagc gaagtaatta gctattggcg tggattagct
    21001 gatacaggtc aaggttatga tgccgacctt gcgtggggct ggcaatgtgc tgatgtgact
    21061 aatgggacaa ctactaactt ttttggagtg acgctttggg gaaatgcgat tgacttacta
    21121 gatagcgcga aggcgcaagg gttagaggtt atctatgacg cccctggaat aaatcccaaa
    21181 gctggtgatt tgtttgtgat gtttacttac ggacatcctt atgggcatac aggaattatc
    21241 attgctgata gcgacgggta cactatccag acgattgagc aaaatgttga tggctactca
    21301 gacaataacg gtgacggcat taacgatcag tttcaagttg gcggaccagc tcgctatgtc
    21361 actcgtgcct tttcagacgg cgacgggtat atcgtgggtt ggattagacc gccttatagc
    21421 gatacctcat ctgaaaagca atcacaatca caagcgccat caggattccg gaaattaaaa
    21481 gacgaggtcg gaacatttga ggttatggtc ccagcgctaa acgttcgccg tgaaccaagc
    21541 ttaaatggcg agattgtagc ttgttaccaa tacggcatga caggaactta tgattctgtc
    21601 tatgttggcg atgggtatat ttgggtgtct tatgtcggtg catctggcat gagaaattat
    21661 atggctgttg gagacgctga tggcgattac aatgtcaatc catattgtaa attttattaa
    21721 aagggggtta tatgggatat aactcaacca accttaaaca ggttgacggt ggcgatgtta
    21781 tcaaacaagg tgatacatcg tcacttttta gttttaattt gttggacgaa aacaacaacg
    21841 ttattgattt aaatggcaaa caagcgacta tttactttac acgtaatcgc aaaacctatc
    21901 taaccaaaac aactgatgtt attgacaaca aagttgattt tacgattaat aagattttgg
    21961 agattgggac atactatatc gaagtgcact gcgatggcta tgtctttccg tctgacgaca
    22021 gcgtaacgct tgatgttaga cgttctgggc aaaaatatgt cgttagcact gatttaatca
    22081 cagacacaac tatccaaaaa ctatcagctg atattgagta tttaaaatca aaagtgactc
    22141 aaaatcagca tctatttgag caagtgtcac cacaaacaga atggaccatt acacataatt
    22201 tgattaagta tccatctgtg acaattgttg atagtgcagg taatgaggtt tttggaagtg
    22261 tcgagtacat tagcacaaca aaaatcatcg ttagattctc agcgccattt gctggcaaag
    22321 ccattttaaa ttaaaggaga ttacatgagt acatttttaa caaatatcaa ccttaataaa
    22381 aacgagttgc aaaatgcagt cgtacaaaat ttagctaaag aaccgcatga accaaaatca
    22441 ggacaatttt attttgacag tgctgctaat aatctaaaaa tctataatgg gacatcttgg
    22501 gttgttttag acaaggaaac agcagaaagc attgttgacc ttattaattc tggtaaatcc
    22561 aaaatcgata aatcaaaagt cgatggactt gaagaagcaa ttaatcaagc gtctatgact
    22621 ggtcaagcta tcgcgaccgc tttaaacgaa gatactggtg gcgttactgt aaaccaaaat
    22681 aaaattacag ggcttacaga taaactagct gaaattgcga ctaacaaagc gtcagcgact
    22741 cgggagtcac aagatgcttt gcaagaagcc aaggtgtatg ctgaccaaaa agtagccgga
    22801 cttgttgata gtgcatcaga agattacaac acgtttaaag agctagaaac ttttattaaa
    22861 caaaacgcga aaggtctcgc agcaatctca aatgtagcca aaaaatttag taaaacgttt
    22921 ggcgatgcac gagctaaaga atttacaatc acacacaacc taaaaactcg tgatgttaac
    22981 gtcactatcc gagagactaa cttcccttat gcaatcgtct acgcagatat taaagtcaca
    23041 gacgaaaata gcatcttaat cgcaacaggt gcagaagtat taacgcaaaa tcagtatact
    23101 gtgacaatta ctggatagga ggccgctatg agatatattg gcgaatcaca actctcaaaa
    23161 gaccttgtaa caaaagatta tgtagataac aaagtgacta atctcgcgag taaggatgat
    23221 attgttaatt taggtaaaat taaggactcg caaacaggtg cgtttttgga agtcaaaata
    23281 gtcccaaacg gtcaagtccc ttatgacacc actggcatga ttgtgtttga acgctctgga
    23341 ggtaagtaat gtcagtacaa gagataccag ataaaatttt ttatcgatta atagagcaaa
    23401 cagtagaggc aaagctggtt tgggataagg acacacaaat aggtagctat tatatatcca
    23461 tacacgataa gtatagtttt gaatctggta gagatgttaa catctataaa atcttatcta
    23521 gcacacaggc tgatgtgtat aaagctaata agtataatta tcaatcatca tcaaaaccag
    23581 atactagcgt accacagccg aagccaccag agcaacctcc gctcaaaaac aagtctttgt
    23641 atcaatcaat cacgattgat ggactgccaa tagctcgcgt tatttgtaat aatcaggtca
    23701 tttggtctca atcagcagag cctcaggaag tttacaacat tacagcgtac gtagatgcta
    23761 gcgtatctaa gctaaatgac tctgccatta ttgattacaa tcgagatttt gcggcttacg
    23821 gcgtaaattg gagtcgagtt gatagagtcg ccgttgaagt cgacgataaa atagttgcta
    23881 agctacaagc tcctgtctat gattttggtg ttagaggtgg cacgacgatg tctgtcgaaa
    23941 aatgggatta cccatcaaat acaatagaca aatacaaaaa tccaacattt aaaattttgc
    24001 agcattagga ggtaaagctc ctttagataa gacaaaaccg ctcatcaaat gagcggtttt
    24061 tacattaata aaagaattgc aataaaattt ctaaatccag cagtaggtaa ggttgccaaa
    24121 agcaaaaagt tacttggttg ttaggtagac ttcaatttgg cttgtgtttg agtcaagcgt
    24181 ttcattatct ttatatatca taagatattt agattgagta aattctggtt cagggaaaaa
    24241 atcaaac
//
LOCUS       DAUGJR010000029        23549 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUGJR010000029 DAUGJR010000000
VERSION     DAUGJR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23549
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.029"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            142..1356
                     /gene="sstT"
                     /locus_tag="VH800_001206"
     CDS             142..1356
                     /gene="sstT"
                     /locus_tag="VH800_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEQ8362280.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASKETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMLFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(1411..2085)
                     /locus_tag="VH800_001207"
     CDS             complement(1411..2085)
                     /locus_tag="VH800_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEQ8362281.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(2095..3486)
                     /locus_tag="VH800_001208"
     CDS             complement(2095..3486)
                     /locus_tag="VH800_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEQ8362282.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSLEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFEKPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(3556..4269)
                     /gene="rsmG"
                     /locus_tag="VH800_001209"
     CDS             complement(3556..4269)
                     /gene="rsmG"
                     /locus_tag="VH800_001209"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEQ8362283.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKSLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            4419..4976
                     /locus_tag="VH800_001210"
     CDS             4419..4976
                     /locus_tag="VH800_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEQ8362284.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            5023..5919
                     /gene="htpX"
                     /locus_tag="VH800_001211"
     CDS             5023..5919
                     /gene="htpX"
                     /locus_tag="VH800_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEQ8362285.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            6153..6686
                     /locus_tag="VH800_001212"
     CDS             6153..6686
                     /locus_tag="VH800_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEQ8362286.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VCYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            6953..7639
                     /gene="covR"
                     /locus_tag="VH800_001213"
                     /gene_synonym="csrR"
     CDS             6953..7639
                     /gene="covR"
                     /locus_tag="VH800_001213"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEQ8362287.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            7645..9147
                     /gene="covS"
                     /locus_tag="VH800_001214"
                     /gene_synonym="csrS"
     CDS             7645..9147
                     /gene="covS"
                     /locus_tag="VH800_001214"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEQ8362288.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMVRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            9362..9856
                     /gene="nrdR"
                     /locus_tag="VH800_001215"
     CDS             9362..9856
                     /gene="nrdR"
                     /locus_tag="VH800_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEQ8362289.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            9840..11015
                     /locus_tag="VH800_001216"
     CDS             9840..11015
                     /locus_tag="VH800_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEQ8362290.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGDLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            11016..11918
                     /gene="dnaI"
                     /locus_tag="VH800_001217"
     CDS             11016..11918
                     /gene="dnaI"
                     /locus_tag="VH800_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEQ8362291.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            11981..13291
                     /gene="der"
                     /locus_tag="VH800_001218"
     CDS             11981..13291
                     /gene="der"
                     /locus_tag="VH800_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEQ8362292.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            13498..16596
                     /locus_tag="VH800_001219"
     CDS             13498..16596
                     /locus_tag="VH800_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8362293.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQALIEFLWRLASDTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALRLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            16839..17441
                     /locus_tag="VH800_001220"
     CDS             16839..17441
                     /locus_tag="VH800_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362294.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQTPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            17481..18809
                     /locus_tag="VH800_001221"
     CDS             17481..18809
                     /locus_tag="VH800_001221"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEQ8362295.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            18855..19337
                     /locus_tag="VH800_001222"
     CDS             18855..19337
                     /locus_tag="VH800_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8362296.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEEHIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            19449..21023
                     /gene="mltG"
                     /locus_tag="VH800_001223"
     CDS             19449..21023
                     /gene="mltG"
                     /locus_tag="VH800_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEQ8362297.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            21096..21578
                     /gene="greA"
                     /locus_tag="VH800_001224"
     CDS             21096..21578
                     /gene="greA"
                     /locus_tag="VH800_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEQ8362298.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(22201..23124)
                     /gene="yidC"
                     /locus_tag="VH800_001225"
     CDS             complement(22201..23124)
                     /gene="yidC"
                     /locus_tag="VH800_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8362299.1"
                     /translation="MKLTLNRILFSGLALSILLTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(23206..23484)
                     /locus_tag="VH800_001226"
     CDS             complement(23206..23484)
                     /locus_tag="VH800_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEQ8362300.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
BASE COUNT         7616 a         4016 c         4746 g         7171 t
ORIGIN      
        1 aagattactt cgatagtcaa tagaaattga ctgaaaattc ttagcacaaa aaatggttaa
       61 gatatgtagc tcattcgatt tgacgaatag atagaattat attattataa aaaacatgta
      121 actttagtaa ggatgtaacg tatgaaaaaa atatatgatt tatgggttag ggttagtcta
      181 atcaaaaaaa taggtatcgg tgttgtaata ggagtcatgt tgggcatttt ggctcctgat
      241 cttacaggtt ttagtatttt aggaaagtta tttgttggtg gtttaaaggc tatcgcacct
      301 ttgcttgtat ttgctttggt ttcccaagct atctcccatc agaaaaaagg gaaacagact
      361 aatatgacat taatcattgt tctgtattta tttggtacct ttgcgtcagc tttagtagca
      421 gtactgacag cttatctatt ccctttgacg ttagtgttaa atacacctgt aaatacagaa
      481 ttatcaccac ctcaaggtgt tgctgaagtt tttcagtcac ttctattaaa attagtggat
      541 aatccgatca atgctttagc tactgccaat tatattggtg tgctatcatg ggcaattatt
      601 tttggactag cattaaaggc tgcaagtaaa gaaacaaagc atcttataaa aacagcggca
      661 gaagttactt cacaaatagt tgtttggatc atcaatctgg cacctattgg gattatgagt
      721 ctggtgttca ctacgatttc tgaaaacggt gttggaatct tatctgatta tgcttttttg
      781 atactagttt tagtaggaac aatgcttttt gtcgccttag tggttaatcc acttattgcg
      841 gttttgatta cacgacaaaa tccttatccc cttgtcttga gatgtttacg tgagtcaggt
      901 cttacagcat ttttcacacg aagttctgca gccaatattc cagtcaatat gcaattatgc
      961 caaaaaattg gattgagtaa agatacttat tcagtgtcaa ttccacttgg agcaactatt
     1021 aatatgggtg gggcagcaat taccatcaat gtcctaacgc ttgctgctgt acacactttt
     1081 ggtattccta ttgattttct aacagccctc ttacttagcg ttgttgctgc tgtctctgct
     1141 tgtggtgctt ctggtgttgc tgggggatcg ttgttactta ttcctgtagc atgtagtttg
     1201 tttggcattt caaatgatct tgcgatgcag gtggttggtg ttggttttat tgttggtgtt
     1261 atccaggatt cttgtgagac agccttaaat tcgtcaaccg atgttctttt tacagctatt
     1321 gctgaaaatg ctttttggaa acgtaaaaaa gcatagctag atttaacata gtaaaaaaca
     1381 tccttggaaa acgccaagga tgttttttta ttatttaaga tagccaagat aatcaaattt
     1441 ttcaaaggtg tggtcattag cgatggccac aatgatagta ttcggttcta aaggttcaaa
     1501 aggtttgaca ttagtatcta aggttttaac ttctttttga cgcatgccaa tcacatttaa
     1561 ctcatattta cgacgaacat ctagttcgga aagagattgt ccttcccagc ttttaggaat
     1621 gacaaattca atcatcgaaa taccatgttc caaatagatg atgctttcga tatgacgtct
     1681 taacagattt gaagctacac gttttccaga atcacgttca ggggtgatga ctttagttgc
     1741 tccgatgcca tatagaactt cttcaaaaat tttattttta gccttggcaa taatggttgg
     1801 aacaccgagt tttttacagt gcatgactgc aagaacagaa gattccaagt tattccctga
     1861 agcgataacg acagtatcac aatgttcaat ccctacagct aatagaaatt ctttgtcagt
     1921 aatatctcca acagcggctt tagtgaccaa gtcggccacc tctttgacat gactttctct
     1981 gatatcaata gcaataacgt cttgatcaaa gttacttaat tctctggcaa cagtacggcc
     2041 aaaaatacca aggccaagaa cgccgacagt tttacgtttt aacatgtttt ctccttaacc
     2101 cactagaata tcagtagtgg catattgaat ggttttttct tttcgttgaa tcagactgat
     2161 gaggacagta attgggccaa cgcggccgac gaacatcaag acaatgacaa taagacgtcc
     2221 agcagtagac aattgtggtg tcaaatccat agatacccca actgtcgcga tggcagaaat
     2281 agattcaaat aagagtggta taggagcgat atgaggctcc acgctaagta ataaaataaa
     2341 acctatcata agaactgcaa aaaagaagat aagaactgtc atggtctgct taattgtctt
     2401 atttgcgata attcggttac gaaaggtaac ttctgattgc cctgaaagtt ccgctttaaa
     2461 gagtaagaaa gtaatggcag cagtcgtcac tttaatacca ccagctgttc caccaggagc
     2521 accaccaata accatttgaa tcatataaag aatgttagtc ggtgctaggg tatcgttata
     2581 agagattgtt gcaaagccag ctgttctcat agtgactgtt tgaaaaaatg aaaccataag
     2641 ttgctgatgt aaactaaaat tggcaatggt tttgctgtta tctttttcta aaaaccaggt
     2701 taagaaggtt ccaagaaaaa gaataacagc tgtggtttgt agtactagac gagactgatt
     2761 ggataattta cgaaaagttg ccccataaca atgaggtttt tcaaaaaagt attttttaaa
     2821 agctactcct aaatcaaccc aaaccgcaaa accaagtcca ccagagataa tcaagaacgt
     2881 aatgataaca tttaatgtag gatttaacat aaagtctttt aaactagaag atcctaaatt
     2941 gtcaaaacca gcgttacaaa acgccgacac agctaaaaaa atactattga agataccatt
     3001 tttccacccg aagcggggga tgaagtcaat catgataact atcgcagcaa aggcttctag
     3061 actaaaggtt actttataag caaaaaaaag gtagtgcttt aaatctttgc tatcacctcg
     3121 atttaacgct gattggagca aggtttgatc gctcaatcgc atttttcgct tgagggcaaa
     3181 agtactcaca gctattaacg tcaccaagcc aagaccacca atctgcatta gtgccatagc
     3241 aatggtttgt ccgataccgt tatacacttc agcgacggga acaacagaaa gtccagtcac
     3301 acaaaccatg gaaaccacat taaagaaatg atcaagatag acggtattag gaccattttg
     3361 ataatgggta aagggcatgg ataacaagag agtcccaatc agaatcacaa tggcaaaact
     3421 aaatgttaag cgctgtgtga ctgaaagaga tttgataaaa gagcgtttca tgtttcctcc
     3481 agacataata tctcctacta taataacaaa aataagttaa aaaagctaag tttcatctta
     3541 gcctttggta ctattttata gaggtttttt gttaggcaag ccagcttttc ttggatactt
     3601 gttaggtgtt tcctttttct tctcaacaat ggtgatgaag cgagaatctc catttggcaa
     3661 ttggtagcta tggtttttaa tgactttacc aaaaagaaga caaagagcat tcttagcttc
     3721 ttctaactct tggtcagcag cttgtgcctt taaggcgatt aattttcctc caatttttaa
     3781 aaaggggatg gttaattcag atagaacctg catccgagca accgctctgg cagtaacaac
     3841 atcaaattga cctcgaaagg ccttgtcctg tccgaaatct tctgctctac catgaaaaaa
     3901 gtggacattt tccaagccca attcctgagc aaggagtgtc agaaaagaaa tccgcttatt
     3961 aagagaatca ataatggtaa cctcaaggtt tgggaaaaga attttcatgg gtaggctagg
     4021 aaaaccagct ccagctccaa tgtccaataa tttgattggt tcattagcta aaaagccctg
     4081 taaaatagga gcgatggaat cataaaaatg cttgaggtaa acctcatttt cttctgtaat
     4141 agctgttaaa ttaattttag tgttccattc cactagtgat ttgaagtagg tgtcaaattg
     4201 ttctttttgt ttcgatgata aggaaaaacc atcttcctct agtgttcggt aaaagtcttg
     4261 gggtgtcatt tgtatcctct gtttttgata gttgttacca ttctatcata aaatagccta
     4321 taacaaaatc caataaatca tcagaaataa cacctcatta cttgctatta gcctagaaat
     4381 tgctataatt gagacacaaa gattaaagga gacccactat gccaacagtt ttgattatct
     4441 tagtcgtttt aggagtgctt gcgctatggt taatgattag ttacaatagc ctggttaaat
     4501 ctcggatgca cacaaaagaa gcttggagtc agattgatgt gcaattaaag cgtcgtaatg
     4561 acttgattcc aaatcttatt gaaaccgtaa agggatatgc tagctacgag caaaagacat
     4621 ttgaaaaaat cactgatttg cgtgcgcgtg ttgcgaatgc ctcaactcct caagaaacca
     4681 tggcggcttc taacgaattg agtaaacaag tgaccagttt gtttgccgtt gctgaaaatt
     4741 acccagactt aaaagctaac gaaaacttct tgaaattaca agaagagttg accaatacgg
     4801 aaaataaaat ctcatattct cgtcaactct ataattcaac aacgtctaat tacaaccttc
     4861 aattagaatc tttcccaagc aatatcgctg gtaaattatt tggttttaaa ccaagtgaat
     4921 tcttacaaac accagaagct gaaaaagaag ttccaaaagt tgaatttaac ttttaaatat
     4981 gaaattatca tctagtaggc aatcataaga gaaaggagaa ttatgcttta tcaacagatt
     5041 tcacaaaata agcaacgaac agttgtttta ttagttgttt tcttcgctct cttagcactt
     5101 attggagctt cagcaggcta tctgctgtta gataattatg ccatgggctt ggtccttgct
     5161 cttgtcattg gggtgattta tgctaccagt atgatttttc aatccaccag tcttgtaatg
     5221 agtatgaaca atgctagaga agttacagaa aaagaggctc caggcttttt ccatattgtc
     5281 gaggatatgg ctatggtggc ccagattccg atgccgagag tttttattat tgaagatcct
     5341 tctttaaatg cttttgcgac aggatctagc cctcaaaatg ctgctgttgc agcaacgaca
     5401 ggtttacttg aagtcatgaa tcgtgaagaa cttgaaggtg ttatcggcca tgaaattagc
     5461 cacatccgaa attatgatat ccgtatttcg actattgctg tagctttggc gagtgctgtt
     5521 accgttattt ctagtatcgg tgggcgtatg ctatggtatg gtggcggttc tcgcaggcaa
     5581 agagatgacg gagatgatga tgttttaaga atcattacat tacttttgtc gttattatct
     5641 ttgcttttag cgcccctagt agcaagtttg attcagttgg ctatttctcg tcaaagagaa
     5701 tatctagctg atgctagttc tgttgaacta acaagaaatc cccaaggtat gattaaggct
     5761 cttgaaaaat tgcagttatc tcagccaatg aagcatcctg ttgatgatgc tagtgcggcc
     5821 ttgtatatta atgagcctcg caaaaaaagg agcttcagtt cattattcag cacccatcct
     5881 cctattgagg agaggattga aaggttaaaa aacatgtgag cgtttggggt ttttgctcaa
     5941 gcctcacttt tttatgtctt tgggcagata atctaaaatg gcaggaatta tcaaaaatat
     6001 ctgaacaaaa agaaaaaaat gagtgaaaca atggttaaaa atagaatgat ttaaatctta
     6061 aaattaaaaa acgtcagaaa ataaatgcaa aactattgac aaatctttta gatagtagta
     6121 aaaataaatg agagttttat taggagaaga tgatgttagc tatttccgaa atcagaaaac
     6181 acccagacgg tctctcgttt gatcgtttat gtgatgtcaa aagtatgtta cttgagcgtg
     6241 accaacagat tattgacata aaggcagtta aagctgtcgg taatgtttgc tatgataagg
     6301 ggctttatct gttagattat caattgagtt acgaagtgat attaccgtct agccgttcta
     6361 tggttccggt ctgtttaagt gaagtccaac acattcaaga attatttata gaggcgacag
     6421 atttagctga taagaaagag ttggttgaag ataatctggt attagtttta gacaaagacg
     6481 ctattaacct cgaagaaagt attgtggata atatcttact tgctattccg ctacaggtct
     6541 tgacagagga agaaaagaaa tcaaaagagt tgccagcagg tcaaaattgg gcagttttga
     6601 cagaagaaga ctaccagtgt ctaaaagaag aaaagcaaaa agaaaataat ccttttgcta
     6661 gcttgcaagg gttgtttgat gaataaaact gaatattaaa gatgtctgta atttttattt
     6721 gaaaaaacag ctattctttg atatactctt tagagaatat ggttacttat ctaaagtaga
     6781 aggtattttg accatagagg gcagagaagg taatgactat tagatgcttc atattttatt
     6841 cgctagaaga ctatttgacc attagaactg aaatagtcta ggatatgaga tgaatttcat
     6901 agttttcttt ctgggagaaa aagatagatt aagaggataa gggttggtat aaatgacaaa
     6961 gaaaatttta attattgaag atgaaaagaa tctggctaga ttcgtttctc ttgagctgca
     7021 acatgagggt tatgaagtca ttgttgaggt caatggtcgt gaagggttag aaactgcttt
     7081 ggaaaaagag tttgatttaa tcctgcttga cttaatgtta ccagagatgg atggttttga
     7141 agtgacccgt cgtttgcaaa ccgaaaaaac aacgtatatc atgatgatga ctgcgcgtga
     7201 ttctattatg gatgtggttg caggtttaga ccgcggtgca gacgactata ttgttaaacc
     7261 gtttgccatt gaagaactac ttgcccgtat tcgtgctatt ttccgccgtc aagatattga
     7321 atctgagaag aaagtgccta gtcaaggcat ttatcgagat ctagttttaa atccacaaaa
     7381 ccgttcagtt aatcgtggcg acgatgagat ttctctcact aaacgtgaat atgatttgct
     7441 taatattttg atgactaata tgaatcgtgt catgacacgt gaagaattat tgtcaaatgt
     7501 ttggaaatat gatgaagccg ttgagactaa tgttgtagat gtctatattc gttatctccg
     7561 cggcaaaatt gacattccag gcaaggaatc ttatatccaa acagtgcgtg gcatgggata
     7621 cgttattcgt gagaaataag tcatatggaa aatcagaaac aaaaacagaa gaaatataaa
     7681 aattcgttac caaaacgact atctaatatc ttttttgttc tttttttctg cattttctct
     7741 gcctttacac tgattgccta tagttcaaca aactatttct tattgaagaa agaaaagcag
     7801 tcagtctttc aagctgtaaa tattgttaga gttcgtcttt ctgaggtgga ctctaatttt
     7861 acattagaga acttagcaga agttttgtac aaaaacgata aaacacatct gagaattgat
     7921 gacagaaagg gcagtcgagt cattaggagt gagcgcgata tcacaaatac tctagatgcg
     7981 aatcaagata tttatgtcta taacattgat aaacagatga tttttaccac agataacgaa
     8041 gaatcatctc ctggcttgca tggtcctatc ggtcgtgtgt atcacgacca tatcgaagat
     8101 cagtatcgtg ggttttccat gacacaaaag gtatattcta atcggactgg aaaatttgtg
     8161 ggctatgttc aagtctttca tgatttaggc aattattatg tcattagagc aagactgctg
     8221 ttttggctac tagttgttga gttatttggc acaagcttag cctatttaat catcttaatt
     8281 actacgcggc gctttttgaa gcctttacac aatttacatg aagtgatgcg taatatctct
     8341 gaaaatccta ataatttaaa cctgcgctca gatatttcgt caggagatga aatcgaagaa
     8401 ttgtctgtta tctttgacaa tatgttagac aaattggaga cacatactaa gttgcaatca
     8461 cgttttatta gtgatgtcag ccatgaatta cgaacaccgg ttgcgattat taaagggcat
     8521 attggtctct tacaacgttg gggtaaagat gacagtgata ttcttgaaga aagcttgaca
     8581 gcaacagcgc atgaggctga ccgtatggca atcatgatta atgatatgtt agacatggtt
     8641 cgcgtacaag gctcatttga gggacatcaa aatgatatga cagttttgga agattctatt
     8701 gaaactgttg ttggtaattt tagagtttta agagaagatt ttatctttac atggcagtca
     8761 gaaaatccaa aaacgatagc ccgtatttat aaaaatcatt ttgagcaggc tttgatgatt
     8821 ctgattgaca atgctgtgaa gtattcccgt aaagaaaaga aaatcgcgat taacctttca
     8881 gtgactggca aacaagaagc tattgttaga gttcaagata aaggcgaagg aatttctaaa
     8941 gaagatattg aacatatctt tgaacgcttt tatagaacgg ataaatcacg taatcgaaca
     9001 agtacccagg ctggattagg gattggcttg tctattctca agcaaattgt agatgggtat
     9061 catttacaga tgaaggttga aagtgaatta aatgaaggtt cagtgtttat cttacatatt
     9121 cctttggccc agtctaaaga gagttagagt agcttaaggc attgttaatg tgacaggtat
     9181 agtatgtaat cattagataa tagtagcagt cttttgccac aactggttag aagctgatgc
     9241 tattttttta gcaatgatgg atgacatgaa agaaatactg tcaatcgcga tgtcttttgt
     9301 tatccttgag aatatggtaa aatagtatat tagattaatt tgatagaatt ggggtgtttg
     9361 cgtgcgttgt ccaaaatgta attaccataa atcgagtgtt gttgacagta gacaagctga
     9421 agacggcaac accattcgtc gtcgaagaga atgtgaacag tgtcatactc gctttactac
     9481 ctttgagcgt gttgaagaac tccctttatt agtcatcaaa aaagatggca cacgagagca
     9541 attttctaga gataaaatat taaatggggt tgttcaaagt gcgcaaaaac gacctgtctc
     9601 gagcacagat attgaaaatg tcatttctcg tattgaacaa gaagttcgaa caacctacga
     9661 aaatgaagtg tcaagtactg ctattggtaa tttagtgatg gatgagttgg ccgaactcga
     9721 tgaaatcaca tatgtacgct ttgctagtgt ctacaagagt ttcaaggacg ttgatgaaat
     9781 cgaagaactt ttgcaacaaa ttacgaatcg cgtacgcgga aagaaaaaac gtttaaataa
     9841 tgatgaaacc aattgatact tttacatatc taaaacgcaa caaagtaact cttgattcgg
     9901 tgactttaat acagttgtac tttccaatta ttggaagtga cgcggtctct atctaccaat
     9961 actttattca cttttttgac gatggtttac aacgtcataa attcagcgat attttaaatc
    10021 acctacagtt tggtatgaaa cgttttgaag atgctcttgc tatattgaca gcaatggaat
    10081 tagtgagtgt gtatcagcta tcagatacat atcttattac gttgcaccag ccgcttagcc
    10141 gtgacttgtt ttttcaacat ccagcttatt ctcgattatt agaacaaaag attggagagg
    10201 tagctgtctc tgagttgcag gtaactgtcc caagtcaagc aagaaatatt tctaagcgat
    10261 tttcggatat ttttggggtg caaggagatt tgacgaacgt acctcaaaag ccacaaaaga
    10321 attttgacct ttcaagtttc cagcaattaa tggttcgtga tgggttacaa tttgaagata
    10381 atcaaaaaga tatcattagc ctttacagta ttgctgaaca gtatgatatg acgtggtttg
    10441 atacttatca aatagctaag gcgacggctg ttaatgggaa aattcgacct gaacgcttat
    10501 tggctaaaaa aaatcaaagc atgacaaaac caagcaaaga aaatttttca caggctgagc
    10561 aaattatttt gcgagaagca aagcaagaca gtgctttagt ctttttggaa aaaattaaaa
    10621 aggctagacg tgcaacgatt actaaggatg aacgcatttt attgcaaaca ttggccaaaa
    10681 tgaattttct tgatgatgtt atcaatgtca tggtgcttta tacctttaat aagacaaaat
    10741 ctgctaattt acagaagagt tatgtcttaa aaatggccaa tgatttcgcc taccaaaagg
    10801 tgtcaacggc tgaagaagct atagtggttt tgcgagcctt cacggatcgt caaagtcgtc
    10861 ggcaatcaaa agtaaaaaca agtcaaagta atgtgcctaa gtggagcaat cctgattacc
    10921 aagagacaac aagtcaagaa gagcaggcga aactagatca gttcaaacag gctgctttga
    10981 agaggttaga aaacctagga aaagggggtg actagatgga aaagattgga gaaaccatgg
    11041 cgaaattggg tcaaaacact cgtgttaata gcgaccagtt gattcaaacc attttagcgg
    11101 atcctgaagt agcaagcttc atcagtcaac atcacttatc tcaagagcaa attaacctta
    11161 gcttatctaa gttcaatcaa tttttggtgg aacgccagaa gtatcaactc aaagatccct
    11221 cttatattgc taagggctat cagcctattc tagctatgaa tgagggctac gctgatgtgt
    11281 cttatttgga aaccaaagaa ttggtagaag ctcaaaaaca ggcagctatc tctgaacgga
    11341 ttcaactggt tagtttgcca aaatcctatc gccatattca tttatcagat attgatgtta
    11401 ataatgcgag ccgtatggaa gccttctctg ctattttaga ttttgtggaa caatacccat
    11461 cagcagagca aaaaggcttg tatttgtacg gagatatggg aattggcaag tcttacttgt
    11521 tggctgctat ggcccatgaa ttgtctgaga aaaaaggtgt gtcaacgacc cttctacatt
    11581 ttccgagctt tgccattgat gtaaaaaatg ccatttcaaa cggctctgtt aaagaagaaa
    11641 tcgatgcggt caaaaatgta ccggtgctca ttttagatga tattggtgca gagcaagcca
    11701 cttcttgggt ccgtgatgag gtgttgcagg tgattttaca ataccgtatg ttagaggaat
    11761 tgccaacctt ctttacctct aattacagct ttgcggattt ggagcgaaaa tgggcaacca
    11821 tcaaaggaag tgacgaaact tggcaggcca aacgtgtcat ggaacgcgtg cgttatttgg
    11881 ctagagagtt tcatttagaa ggggctaacc gccgttaagt ttgagatagc aatcaagaag
    11941 aatagctaca cgtatgagtg agtgaaagaa aaggagaatc atggttttac ctaccgttgc
    12001 cattgtgggc cgtccaaatg tgggcaagtc caccttattt aatcgaatcg caggagagcg
    12061 catttcaatt gtagaagacg ttgaaggggt tactcgtgac cgtatttatg ctactgggga
    12121 gtggcttaac cgccaattct cattgattga tacaggtggt attgatgacg ttgatgcccc
    12181 gtttatggag caaatcaagc accaggctca aattgccatg gaagaagctg atgttatcgt
    12241 ttttgttgtt tctggtaaag aaggggtgac cgacgctgac gaatatgtgt ctaaaattct
    12301 gtatcgaacc aataccccag tcattttagc tgttaataag gttgataatc ctgaaatgcg
    12361 taatgacatt tatgattttt attcacttgg tttgggtgat ccttatccag tttcttctgt
    12421 tcatggtatc ggaacagggg atgtcttaga tgcgatcgtt gaaaacttgc cagtagaaga
    12481 ggctgaagaa aatgatgata ttattcgctt cagtttaatc ggtcgtccta atgttgggaa
    12541 atctagcttg attaacgcta ttttaggtga ggaccgtgtt atcgctagcc ctgtcgcagg
    12601 gacaacacgt gatgccattg acacgcattt tacggatgct gacggtcaag aatttaccat
    12661 gattgacacg gctggaatgc gcaaatctgg caagatttac gaaaatacag agaaatattc
    12721 tgtcatgcgt gccatgcgtg ccattgaccg ctccgatgtg gtcttgatgg ttatcaatgc
    12781 tgaagaaggt atccgtgaat acgacaagcg tatcgctggc tttgcacacg aagctggtaa
    12841 aggaatgatt atcgtggtta acaaatggga taccattgac aaggataatc ataccgttgc
    12901 taagtgggaa gccgatattc gtgaccaatt ccaatttttg acatacgctc cgattatttt
    12961 tgtgtcagct ttgacgaagc agcgcctcaa caaattgcct gacttgatta aacgtatcag
    13021 tgagagtcag aataaacgta tcccatctgc tgtcctcaat gatgttatca tggatgctat
    13081 tgccattaat ccaacgccaa cggataaggg taaacgtttg aaaattttct atgccactca
    13141 agtgtcagta aagccaccaa catttgtcgt ctttgttaac gaggaagaat tgatgcactt
    13201 ctcttatcta cgcttcttgg aaaaccagat tcgcgcagcc tttacctttg aagggacacc
    13261 gattcatcta attgctcgca aacgaaaata agaaatgaac atcaactaaa atgctgacct
    13321 aagaaataat ctcatcattg ataaggactg tgttgtgtat gttacaggag acagtccttt
    13381 ttataatacc tttaagggtg tagacggaag attagtagca aacaaagaaa aaggattttg
    13441 acaagaaata tcagtcggtt tttgctataa tgaaaggata agcaaaaagg tggaaaaatg
    13501 atggctagat taattccagg acgagtaagg aatgaaggta ttaagcttta tgagcaaggt
    13561 ttagtttcat tccaagatga taataaaggc attcttcaaa tagaagtgga gacttatcag
    13621 gttcaatatg gagcagatga tgaggatatc acttgtcaat gcgacacatt tcatatgaaa
    13681 cattattgca agcatattgc agcagtcgag tattttttaa aaaatgatca aaaaggtaag
    13741 ctttttttaa aacagttaac aaatcaaaca aaaatcaaag aaacaacaaa gaaaatgaca
    13801 tcttttggta gcctcttttt agatagctta gccatgaatg aagatgattc tgttaaatac
    13861 aggctgtctg ctcttggtag tcgaagccct ttttcgtcag attactggtg gagtctgaaa
    13921 atcaatcgtt taccagatga tcgttcttat gtgattcggg atattaaagg ctttttgcag
    13981 cttattaaaa aagaaggctt ttatcagatt ggaaaaaatt attttgaaca actttcatgg
    14041 ctgcagtttg acccatctag tcaggccctt attgagtttt tatggcgctt agcatctgat
    14101 actgacaaag gggacaacga gaacattttt ccaaatcatg caaggcattt gcgcttacct
    14161 agtggttttt ttgaagaagg tattcactat ttgacgtcac tttatgactt tacttttgag
    14221 gggccttctc aaacttatca tcatcttttt gtccgttctt tggaagcaga ggcaggcctt
    14281 tatgagttta aagtggaagt gcatcgcaaa tctattgaat tgcaaattgc tgaaaaaaat
    14341 gtgcaatacc tctttgataa tgactatctt ctttatcaag atacctttta tcacttgacg
    14401 ttaaagcaac gaaaaatggt tcaggctatt cgtagtctgc ccattgaggc cgacttggct
    14461 aaacatattc attttgattt ggatgatcat gcgaaattag ctgcaagctt atcagatttt
    14521 aaacagatcg gtctagtaga ggctcctaaa agctttgcta ttagagactt tgaggtgact
    14581 tttcaatttg atttgttaaa tcgagatgaa atcagttgtc agcttatgtt tgattatggc
    14641 aattaccaag ttagtgacaa agcaagttta gaagcacttc cttttgctag tcatttaaaa
    14701 aaagaagaaa aaatcaatcg ttctttactt gcttttggct tctcgccaca attttactca
    14761 aaaaagcgac taacaagtgc aaaagagctc tatacttttt ttgaagaaac agttccatgt
    14821 tttgagcgct taggtaatgt tgcgttgagt acagctatcc aagcattaca agtgaaagaa
    14881 atgcccaaga tcgctattag acgcaatcag ggattactag atatttcgtt tgatttttca
    14941 accattattg aaaatgatat tgaccaagct gttacagctc tttttcaaaa taatccttat
    15001 tttgtgagtc aaacgggtca attagtggtt tttgatgatg aaactcaaaa agttagcaaa
    15061 agtttacaag aattaagagc aagacagcta aaaaatggtc acttgcaact ggatggcatt
    15121 agagctctac aagtatccaa actttttgaa ggcatgacat ctgttcattt ttcaaaggaa
    15181 ttagaagagt tagcctatca tttgcagcat cctgaaactt tttcaataaa accgttacca
    15241 gttaaggctc aaatgcgaga ttatcaacgc aacggtgttc agtggttatc aatgctcaat
    15301 cattatggct ttggtggcat tttagcagat gacatgggac ttggaaaaac tctccagaca
    15361 cttgcttttt tagctagtca cctgaaatca gatagtaaag tgctcatttt atctccatct
    15421 agtcttatct ataattggtt tgatgaatgt caaaaattca cacctcagct agatgttgtg
    15481 gtttcttacg gacttaaaca aatcagagat caaatcatcg aagaaggtca tcaaataacc
    15541 ataaccagct attcctcctt tagacaggat tttgagacct atcaagcgtt tcactacgat
    15601 tatcttatct tagatgaagc tcaagtgata aaaaatgcac aaactaagat ttcacactgt
    15661 ttacgtgcgt ttaatacagc caattgtttt gcgctttcgg gcactcctat tgaaaataaa
    15721 atgcttgaaa tttggtccat tttccaaatt gttttgccag ggttgctacc gactaaaaaa
    15781 gagtttttaa aattaacagc tgagcaagta tcacgctata tcaaaccctt tgtgatgcgt
    15841 cgtaaaaaag aagatgtcct accagaatta cctgatttaa ttgaaactaa ttattcaaac
    15901 gagatgacag atgaacaaaa agctatttac ttagcgcagt taaggcagat gcaagatcaa
    15961 attcgaaatt ctagtgatgt ggatattagc cgtcaaaaaa ttgagatttt atctggtatc
    16021 actcgattga ggcaaatctg tgacactcca agtctcttta tggattacca aggcaaaagt
    16081 ggtaaactag atagtttgcg aatcttattg acacaaatta aagaaaatgg tcatcgggct
    16141 ttgatttttt ctcaatttag agggatgctg gacttggcca agcaagagat gactgctcta
    16201 aggttgacct cttatcaaat gacgggatct acccctgcca atgaacgtca agaaatgact
    16261 agagccttta ataacggttc caaggatgct tttttgattt ccctcaaggc aggtggagtt
    16321 ggaatcaacc ttacgggagc agacacagtg attttaatcg atttatggtg gaatcctgct
    16381 gttgaaatgc aggcaatcag tcgcgcctac cgtattggtc aaaaagaaaa cgttgaagta
    16441 tatcgcttaa tcactcgagg gacgattgaa gaaaagattt tagagcttca agaaagtaag
    16501 cgcaatttgg tgactacagt tttggatggc aatgaaagcc gagcaagtat gtccattgaa
    16561 gaaataaaag aaattttggg gctaaacact cattaatctt ccttgatttt agtgacatta
    16621 aaaacccttt aaagaagatg acaccaaaag caccttatat aacctcgtta aaacgcttct
    16681 ttttgaaata tctttattga tatagcgatt gtcatttgct agtaatgatt aaaacattta
    16741 gaaaaagaca cgtcatagaa tcatcaagga atgctttgaa aaataacagt atttaagtta
    16801 taatagagga tgctacaaga agggagaatc aaaaaaggat ggtaaaaaat cagtttcctt
    16861 tagttgcaga tggcattgct attagtgatc cagcaaagca aatggctctg tatgaaaatg
    16921 aagatctcat taccaacatc cgtggctatt accaggacaa ggagtatgat gatattgcta
    16981 gaaatgagga gtttactgct aaagcaactt ctcggcagac cccttctagt aagcgctttt
    17041 gtagcaatga tgaaaaacac cattatgtca aagaggcgcg tcaaaaagca aagcaagatc
    17101 tcaaggaaaa aagacaggct tatcttgcca aagaaatggc ctatgttcct aaacaggttt
    17161 ctaaaaagca acagcctgcg gattcttctc cttctcaaaa gcaagcaaca acagaaatga
    17221 gtcgttttac aaaaaagctt catcaagaca actatatttt agctgagttg ccaaaagaat
    17281 ataaagagcc aaaaaatctt cctcaacaag gaactacaaa aaaaaataat tacgattttt
    17341 taaaatccag tcaaatttac aataataaag aaatgagaca acaacgagaa aaaacaattg
    17401 cgcaagagct taatcttagt aggtttgagg atcttcctta ataaatctac tcagcgtatg
    17461 cagatgacaa aggagttaag atgtcaaaaa cgtatcattt tatcggaatt aaagggtcag
    17521 gaatgagtgc cttggccctt atgttgcatc aaatggggca taaggtgcaa ggtagtgatg
    17581 ttgaaaaata ctatttcact caaagaggat tggaacaagc gggcatcact atcttacctt
    17641 ttagcgagga caacattacg ccagatatgg aacttatcgt tgggaatgcc tttcgtgaaa
    17701 acaacaaaga agtggcctat gctttgagac accagattcc tttcaaacgt tatcatgact
    17761 ttttaggtga ttttatgaaa tcatttatca gttttgcagt agcaggtgct catggtaaaa
    17821 cttctacaac gggtttattg tcacatgtct tgaaaaatat cacagacaca tcttatttaa
    17881 ttggtgatgg tactgggcgt ggatctgcta atgcacagta ttttgttttt gaatcagacg
    17941 aatacgaacg ccattttatg ccttatcacc cagaatactc tatcattact aatattgatt
    18001 ttgaccatcc tgattatttc acaggaattg ctgatgtgcg aaacgctttc aacgattatg
    18061 ctaagcaggt caagaaagct ttgtttgttt atggtgaaga tgacgaacta aaaaagatcg
    18121 aagcacctgc acctatttac tattatggtt ttgaagaggg caatgatttt atcgcttacg
    18181 acattacgcg tactacgaac ggatcggact ttaaggtaaa acaccaagga gaggtcattg
    18241 gtcagtttca cgtacctgct tatggaaaac ataacatttt aaacgctaca gcagtaattg
    18301 caaacttgtt tgtagccggc attgatatgg ctctagtggc agaccatctt aaaacttttt
    18361 caggtgtgaa acgtcgtttt acagagaaaa ttatcaatga cactattatt attgatgact
    18421 ttgctcatca tccaaccgaa attgtggcaa caattgatgc ggctagacaa aaatacccaa
    18481 gtaaagaaat tgtagcaata ttccagccac atacttttac tcgcactatt gccttattag
    18541 aggattttgc ttgtgcttta aatgaagctg acagtgttta tttagcccag atttatggtt
    18601 ctgcacgtga agtagataaa ggtgaagtta aggttgaaga tttggctgct aagattatca
    18661 aaccatcaca agtagtaacg gtggaaaatg tctctcctct tcttgatcac gataatgctg
    18721 tttatgtttt tatgggagct ggagatattc agctatatga acattctttt gaggaattac
    18781 ttgcaaattt aactaaaaat aaccaataac atgtcctgcc ttaggcaggt tttctcattc
    18841 taaaggagtt tgatatgttg attagacagg ttcaaggatc cgatttggaa gttattgcta
    18901 ccattgaaag tgacaatttt tcaccacaag aagcaacgac aagagcagtt cttgaagagc
    18961 acatacggct gataccagat acttttttag tggcacttat cgatcaggaa attgttggct
    19021 atatcgaagg tccagttgtc actactccta ttttggagga ttctttgttc cacggggtga
    19081 ctaaaaatcc taaaactgga ggctatattg ctattactag tttgtccata gctaaacatt
    19141 ttcagcaaca aggggttggg acagctttgt tggcggcact aaaagattta gtagtagcgc
    19201 agcaaagaac aggtcttatt ttgacttgtc atgattactt gatttcctat tatgaaatga
    19261 atgggtttat taaccaagga atttcagagt ctcaacatgg tggaaccctt tggtaccaaa
    19321 tgatttggaa actttagaat cacagctgat tcaactgttg gtttgttaaa aataagtaac
    19381 aaatgcatca tttaattgca attaggatac ttttaagtta taatggcggt tgattatatt
    19441 taggaggatt ggctttgacc gattttaagg ataaagacca acaagatcag cagcgaagct
    19501 ttaaagagca gattcttgct gagttggaaa aagcaaatca aatcagaaaa gaaaaagagg
    19561 aagaactttt tcaaaaagag ttggaagcta aagaagcagc taggagaacg gcccagctat
    19621 atgctgaata taaaagacaa gatgcttttc aaaaagagtc tatagcacat aacaataaga
    19681 cagctaaaca ctttcaagct ataaaaggtg cggtaatgac ttcagaagcg cttaaaccga
    19741 ctttactttc tgaaaaagaa aactcatctt taaaaacgac aaataagaga gtcgtgcagg
    19801 caaatgagct tcaagagact gcctctaaag aatctcaagt accgttaact attgagaaag
    19861 gtcattcagt gagacgaaaa ttaagcaaac gccaacagac tgagcgagct gctaaaaaga
    19921 tttcaaccgt tttgattagt tctattatta taaccctttt ggctgttact ctagcaggag
    19981 caggctatgt ttatagtgct ttaaatcctg ttgataaaaa tagtgatgcc tttgttcaag
    20041 ttgagattcc atctgggtca ggcaataaat tgattggtca aattcttcaa aaaaaaggtt
    20101 taatcaagaa tagcactgtt tttagttttt atacaaaatt taaaaacttt acaaattttc
    20161 agagcgggta ttataatctg caaaaaagta tgagtctaga agaaattgct agtgctttac
    20221 aagaaggtgg tacagcagaa cctaccaagc catctcttgg gaagatcttg attccagaag
    20281 gatacacgat taaacaaata gctaaagctg ttgagcataa tagcaaggga aagaccaaaa
    20341 aagctaaaac accttttaac gagaaggatt ttttggattt agtcacggat gaggctttta
    20401 ttcaagatat ggtaaaaaga tatccaaaat tattagcaac tatcccaact aaagaaaaag
    20461 ctatttaccg tttggaaggt taccttttcc cagcaaccta taactattac aaagaaacta
    20521 ccatgagaga acttgtagag gacatgctgg cagctatgga tgctactttg gtaccctatt
    20581 atgataaaat tgctgctagt ggtaagacag tcaacgaggt attgaccttg gcctctttgg
    20641 ttgaaaaaga aggttcaaca gacgatgaca gacgtcaaat tgcaagtgtc ttttataacc
    20701 gccttaatag cggaatggca ctacaatcta atatagctat tttgtatgcg atggggaaac
    20761 ttggtgagaa aacaaccttg gctgaggatg ctactattga caccaccatt aattctcctt
    20821 ataatattta taccaataca ggtctgatgc ctggtccagt tgctagctcg ggggtttctg
    20881 caattgaagc aaccctaaat ccagcctcaa cggattattt atactttgtg gccaatgtcc
    20941 atactggtga agtttactat gcaaaaacat ttgaagaaca ctctgcaaat gttgaaaaat
    21001 atgtgaatag tcaaattcag taaacacaaa catggtgctt aagcaccatg tttgtgtttc
    21061 tgattcgttc aaaaaagaaa agagagaaaa caattatggc agaaaaaacg tatccgatga
    21121 ccctaacgga aaaagaacaa cttgaaaaag aacttgaaga attaaaactt gtgcgtcgtc
    21181 cagaaatagt ggagcgtatt aaaattgcac gttcgtatgg agatctttca gagaactctg
    21241 aatacgatgc cgcaaaagat gagcaagctt ttgttgaagg tcaaatttca acgcttgaaa
    21301 ctaagattcg ctatgctgaa atcattgaca gtgatgctgt tgcaaaagat gaagtcgcta
    21361 tcggaaaaac agttatcgtt caagaagttg gaacaacaga taaagatact tatcatattg
    21421 taggtgctgc tggagcagat atcttctccg gaaaaatttc aaatgaaagc ccgattgctc
    21481 aagctttgat tggtaaaaaa acaggtgaca aggttagaat tgaatcacca gcagctactt
    21541 atgatgttga aatcatcagc gttgaaaaga caaattaatc cgatgaagcc attatttgcc
    21601 taaccactaa gtgttttggt tgctaatggc ttttctagta tcttcaaatg aggttgactg
    21661 ttaggaaggt caagtattaa tcgcattgat tatgagtcaa gaggactata gatcaaagat
    21721 cgttttcgat ggttatttaa taccaaaaga aaagaccagc accttaatgt actgacccca
    21781 aaaagttgga cactatattt taagtatagg aagtgtataa tctaaggaaa ctgacactaa
    21841 tgattgaccg ttttgcaaga ctttattaat gatttcttgc tttattttaa atgaataagt
    21901 ctgatatgtt tccttcctta acactatcga ctccataatg acccatcagt caaacggtat
    21961 atctcaaacg actacggttt actccaaatt cattggctag ttgaggccaa gaaacacctg
    22021 attttttaat gctaaatttc tagcttatct tcatagctta atttcataca aaaaaacccc
    22081 aatcgttaga tttttttgat atgtcccctt tcactagatg agtccagtaa aagggggcat
    22141 atcgtttttt gtctaacttt tggagtgcag ttcataattg tgctaggttt tttgtctttc
    22201 ttaacgcttt cgctgttttc cagcattacg attggatttt atttttttag gcaagttagc
    22261 ctgttccatg ttttgtgaag gcgtaacgtc cttacgagaa gaagttgatt ggtatgcttt
    22321 aggcgggttt ttagcgtatt cttctttaat ttgcttatgc aatcgaggtt ttaagaggta
    22381 ggttgtgatt aactgttgaa taatactaaa gaaaccacca actagccagt aaagaccaac
    22441 accagcaggg agtgagaagg acatgaagat catcatgata ggcatggtgt acatcatcgt
    22501 cttcatttgc tcacgttgtt cttctgaaac ggccatcatt gataaccatg attggaagaa
    22561 gtaaagagca gcgataattg ctgttaacac taaactacgg ctaccaagat caatacccat
    22621 aaaggtgctt gttgatactc ctttagtgta ttgagcggca aaatacatgg cagaaaagaa
    22681 tggcatctgg atgagaagag gtagacatcc aatacctcca agagggttaa tcccatgagc
    22741 acgctgagca gccattaatt ctgtttgggc agccattttt tcttcctgac tatttgcctg
    22801 tttgatacgt ttgttgattg gttcaaaaac aggtttcaag aaggccattt tctcagattg
    22861 ataacttgct ttccaagatt gatatagacc tagtggtaag ataagtgttc taacaataat
    22921 ggttacgatg atgatagcca gtccataacc tagtccagca ttgtttgcaa agtaatcgat
    22981 aaagtatgac atgggttttc caagaaattc ccaaatcata cctttgggat ttccgtgagc
    23041 gtctcttccc acacagcctg tcaaggtgag tagaattgac agtgctagtc ctgaaaagag
    23101 gatgcgattt aatgttagtt tcaatgtgtt tatcctttaa ttttaatata cttatctatt
    23161 ttacagtttt tttcagaaat tcacaatagt tctgaaggcc gatttttact tgcctatttg
    23221 aaagtcctga aagtcttcaa aattagccat ggtgacatcc acataagtga cttttgccca
    23281 tttggatggt cctttacgaa cttcttgaat aaatgtggct attttatctg aatcttttga
    23341 ttgggccaga atttcaacgg tcccatcgtt gttattccag acacgaccat aaatatctcc
    23401 tatatctaga gctaaagtat gggtagcgta tcgaaaacca acaccttgta cacgtccaga
    23461 aacaattaaa cgtacttttt gcataagaag ggcctccttg cttttattat agcacatact
    23521 tagcaggaaa tctctttagc taattgtct
//
LOCUS       DAUGJR010000030        22140 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUGJR010000030 DAUGJR010000000
VERSION     DAUGJR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22140
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.030"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            43..3258
                     /gene="rexB"
                     /locus_tag="VH800_001227"
     CDS             43..3258
                     /gene="rexB"
                     /locus_tag="VH800_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEQ8362301.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKSDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVSTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQE
                     KNFQLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLMTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            3219..6887
                     /gene="addA"
                     /locus_tag="VH800_001228"
     CDS             3219..6887
                     /gene="addA"
                     /locus_tag="VH800_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEQ8362302.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCRDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFNEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFSLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVATPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEEMRLLYVAMTRAEKKVYFIGKASKSKSQE
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKLDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            7027..7839
                     /locus_tag="VH800_001229"
     CDS             7027..7839
                     /locus_tag="VH800_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8362303.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLEAPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            7980..8156
                     /locus_tag="VH800_001230"
     CDS             7980..8156
                     /locus_tag="VH800_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEQ8362304.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(8284..8646)
                     /gene="mscL"
                     /locus_tag="VH800_001231"
     CDS             complement(8284..8646)
                     /gene="mscL"
                     /locus_tag="VH800_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEQ8362305.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            8777..10591
                     /gene="dnaG"
                     /locus_tag="VH800_001232"
     CDS             8777..10591
                     /gene="dnaG"
                     /locus_tag="VH800_001232"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8362306.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFHLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKISDLLPNFDYFQVEQSVNALRIQDRQK
                     HQGQIAQAVSNLVTLPMPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     ELLYQRLKQQGHITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            10600..11709
                     /gene="rpoD"
                     /locus_tag="VH800_001233"
     CDS             10600..11709
                     /gene="rpoD"
                     /locus_tag="VH800_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEQ8362307.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLTEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            11945..12283
                     /locus_tag="VH800_001234"
     CDS             11945..12283
                     /locus_tag="VH800_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEQ8362308.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            12421..13275
                     /gene="rfbD"
                     /locus_tag="VH800_001235"
     CDS             12421..13275
                     /gene="rfbD"
                     /locus_tag="VH800_001235"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEQ8362309.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDHPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            13394..14548
                     /locus_tag="VH800_001236"
     CDS             13394..14548
                     /locus_tag="VH800_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEQ8362310.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSRPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLATADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTK
                     QKGQLAELINQVDAGFDSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            14538..15470
                     /locus_tag="VH800_001237"
     CDS             14538..15470
                     /locus_tag="VH800_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8362311.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAVCHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASAIGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            15473..16276
                     /locus_tag="VH800_001238"
     CDS             15473..16276
                     /locus_tag="VH800_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362312.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLSMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            16276..17481
                     /locus_tag="VH800_001239"
     CDS             16276..17481
                     /locus_tag="VH800_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362313.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            17506..18513
                     /locus_tag="VH800_001240"
     CDS             17506..18513
                     /locus_tag="VH800_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8362314.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTIYRMTTDSDSR
                     PTDTPKMIYRIQKLLDTQLNYLKKYNQVDTKEVSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            18510..20255
                     /locus_tag="VH800_001241"
     CDS             18510..20255
                     /locus_tag="VH800_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEQ8362315.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLIIMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDTKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFENWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGDSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            20252..>22140
                     /locus_tag="VH800_001242"
     CDS             20252..>22140
                     /locus_tag="VH800_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8362316.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYAHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNN"
BASE COUNT         7387 a         3657 c         4211 g         6885 t
ORIGIN      
        1 ataatataac aagggtagat tcagtttgta taaaggagtc atatgaaatt aatttacaca
       61 gagatgagtt actcgatgac agagattttg gtgaatgaag cacgaaaagc tgctgaccaa
      121 ggttatcgag tgttctatat tgctccaaat tctctttcat ttgaaaagga aagggaagtc
      181 ttaaccttat tgcctgaacg agggactttt tcgataatag tcacccggtt cgttcaaatg
      241 tcaaggtatt ttacagttga gagctctcct tctaagcaac atctagatga cacgactttg
      301 gctatgattt tttatcgggc cttgatgcaa ttaaaaccag aagatttgcc gagttatggt
      361 cgtttgcaaa ataattcggt ttttattgaa caactagttg agttatataa agaattaaaa
      421 aacgcacaat taagcgtaca tgatttaaca gggttagacc atcctcaaaa acaagaagat
      481 cttattaaaa ttattgagct tgcagagacg atcatgattc agcaagatta taatcaagat
      541 agtcctctac aatcttttgc aagagcaatt aagttaggac ttttaaataa ccaactatca
      601 aaaacagttg ttgttattga tggtttttca cgtttttcag ctgaagagga ttatttatta
      661 tcacttttaa ataacaactg tcaagaggtc atcattggca gttatgtgag tcaaaaagct
      721 tatcaaaaat cttttattaa gggaaatatc tatgaggcta gccttcattt tttgcaagat
      781 ttggctcaaa aataccatat caagccggta tttgcgacct ctaatcaagt gtttaaacca
      841 gccttttcac ggctaacaca attatttgaa gcaactcatg atttttcaca agtagactgg
      901 caactccaaa agagtgatct tgatcacttt agcctttggc aatgtcatca tcaaaaagag
      961 gaaattgaac atgtagcaaa atccattcgg caaaagctat atgaaggtta ccgttataag
     1021 gatatcttag tgttgctagg agatatggat gcttatcaat tacaaattgg gcctatcttt
     1081 gataagtttg aaatccccta ctatttagga aaagcagagc ctatggctgc ccatccatta
     1141 gtccaattta tagaatcgct cgaacgaagt cagcgctata attggcgtcg tgaagacatt
     1201 ttaaacatgt taaaatcagg actttttggt tgttttgatg atagtgatat tgatcgcttt
     1261 gaggaatata ctcagtttgc agatattaaa ggatttacta aattttcaaa gccttttacc
     1321 attaactctt ctaggcagta tcctcttgac tttttaaatg aaatgagaca agacatcgtt
     1381 ttacctttgc aagaattgtt taagagtcaa aaacaacttg gtgcttcact tgttgacaaa
     1441 ttaatacttt ttttaaaaaa gattagatta gctgagaata tgcaaggttt agcacagtcc
     1501 caattagagg tggaaaaaaa cgaagaagtt tggaaaaggt ttacagatat tttgacttct
     1561 tttcatcata tctttggcca agaaaaatta cggctatcag attgccttgc tttaattaaa
     1621 acgggaatga aatcagctca gtatcgtgtt gttccagcga cattagatgt tgtcactatt
     1681 aaatcttatg accttgttca accacattca aaacctttcg tttatgcaat tggtctaact
     1741 caatcacatt ttcctaagca aattcaccat tcaggactac tttctgatca agagcgtgct
     1801 agaattaatg aaataagaaa ttatcgtcat tttgatattg ctagtgccga aaatagtaaa
     1861 aaaaaccatc aaactgcgtt atctctgttt aatgctgcta ctaaggagtt agttcttagt
     1921 gtttcaacgg taatcaacga gacattcgat gatctatctc cttatcttaa agaattaata
     1981 aactttgggt tacctctttt ggataaaggc aaaaactatc tatcttatga taatagcgat
     2041 attggtaact ataaagctct cttgtcacaa attattgcta ttaaccgaca agatcttata
     2101 gaaatgtcag atcaagataa gatgttttgg actgttgtct tacgttatct caggaaacag
     2161 ttaagaaagc aacagctaga gctacctact tcagattatc gtttatcaac aaagcctttg
     2221 tctaaagaag ttatcgaggt atgttttcca aagggaatcc ctttaaagct atctgcaact
     2281 gctttaaccg ttttttataa taatcagtac aactattttt tgaaatatgt tttgaattta
     2341 aacaaaacag aatccattca tccagattcc agaattcatg gtcaatactt gcatcgtgtc
     2401 tttgagcggt taatgaaaga tcacacgcaa gaaccgtttg ataataagtt aaaacaagca
     2461 atctaccata ccaatcaaga aagttttttt cagcaggttt accaagataa tgccgaggct
     2521 gagtacagtt tagctatact agaagatatt gttagatcaa cagcacctat cttgcaactt
     2581 aaccaaaaca tacaggtcat tgatcaagaa aagaactttc agctggatat gggaaatgag
     2641 atattagtcc acgggatcat tgatcgtatt gaccagctga gcgacggtag cttgggcatt
     2701 gttgactata aatcaagcgc gaatcaattt gatattggga ccttttataa tgggttgagt
     2761 ccacaactaa tgacttacct cgcagcctta aaacagattg caccgcacga tataaaccaa
     2821 ttatttgggg ctatgtacct tcatttgcaa gatcctaaat tggatctagt aacatttaaa
     2881 caaattgata acacattagt ggagagtatc tataaagcgt tgacctataa aggtattttt
     2941 tcagaagtcg aaaaagagca tctatctact ggtgcttacc aaaccaaaaa tgctctttat
     3001 tccaatgacg aattggaaac acttttaaat tataacaagt acctctatct taaagctgct
     3061 aaacacatta aaaagggaca ttttttgatt aatccttata caagcgatgg taagacagtt
     3121 caaggagatc aattaaaagc cattacccgt tttgaagcag atcttgacat gggacaggca
     3181 aggcgactag tgactctccc tgctaaggag aaaaaagagt gctttttaac attaatgaga
     3241 aaggagagcc acttgtgatt tcttttgccc catttttaag ccccgaagct attaaacatt
     3301 tgcaagaaaa cgaaaggtgc agagatcagt ctcaaaaacg cacagctcaa caaattgaag
     3361 caatttatac tagtggccaa aatatacttg tatcagcttc tgctggttca ggaaaaacct
     3421 ttgtaatggt cgaacgcata cttgataaaa ttttgagagg tgtttcaatt gatcggcttt
     3481 ttatctcaac ctttactgtt aaagcagcta cagaactgcg tgagcggatt gaaaacaaat
     3541 tatactcaca aattgctcaa actacagatt ttcaaatgaa agtttattta acagaacaat
     3601 tgcaatctct ttgtcaagct gatattggta ctatggatgc ttttgcacag aaagtagtaa
     3661 gtcgctatgg ttatagcatt ggcatttcat cccaatttcg tatcatgcag gataaagcag
     3721 aacaagatgt tttaaagcaa gaggtgttta gcaaactctt taatgagttt atgaatcaaa
     3781 aagaggcacc ggtgtttagg gctcttgtga aaaatttttc tggtaactgt aaagacactt
     3841 cagcttttag agagttagtt tatacttgtt attcttttag ccaatcgaca gaaaacccaa
     3901 aaatatggtt gcaagaaaat tttctaagcg ctgctaaaac ttaccaaaga cttgaagata
     3961 tcccggatca tgatattgaa ctcttacttt tggcaatgca agacactgca aatcagctaa
     4021 gagatgtgac tgatatggaa gattatgggc agctgactaa ggcaggtagc cgatctgcta
     4081 aatacactaa acacttaacg atcatagaaa agttgtctga ttgggtgcgt gattttaaat
     4141 gtttgtatgg aaaagccgga ttggatcggt tgatcagaga tgtgacaggc cttataccat
     4201 ctgggaatga tgttacagtc tcgaaggtaa aataccctgt ttttaagacc ttgcatcaaa
     4261 aattaaaaca atttaggcat ttagaaacaa ttttaatgta tcagaaagac tgtttttcct
     4321 tattggaaca gttacaagat tttgtgcttg cgttttcaga agcttattta gctgtcaaaa
     4381 tacaagaaag tgcttttgaa ttttcagata ttgcacactt tgcaatcaaa attttagagg
     4441 aaaatacgga tattcgccaa tcctatcagc aacactatca tgaggtgatg gttgatgaat
     4501 atcaagataa caatcatatg caagagcgac tcctgacctt actatcgaac ggtcataatc
     4561 gctttatggt aggagatatc aaacaatcga tctatcgatt tcggcaagcc gatcctcaga
     4621 tttttaatca aaagtttaga gactatcaaa aaaaacctga gcaggggaaa gtgattttac
     4681 tcaaagaaaa ctttcgtagc caatcagagg tgttaaatgt cagcaatgct gtttttagtc
     4741 acttaatgga cgaatcagta ggagacgtct tatacgatga gcaacatcag ttaatagcag
     4801 gtagtcatgc tcaaacagtc ccctatctag accgtcgtgc tcagttattg ctatataata
     4861 gcgataaaga tgatggcaac gccccttcag atagtgaggg tatttcattt agtgaggtta
     4921 caattgttgc caaagaaatt attaagcttc acaatgataa gggtgtccct tttgaagaca
     4981 ttacgttact cgtttcttca agaacaagaa atgatatcat ttctcataca ttcaatcaat
     5041 atggtattcc tatagtaaca gatggtgggc agcaaaacta tcttaaatct gttgaagtga
     5101 tggttatgtt agatacatta cgcaccatta ataacccaag aaatgattat gcccttgtgg
     5161 ctttactgcg ctcaccgatg tttgcctttg atgaggatga tttagcaaga atagcacttc
     5221 aaaaagacaa tgagctagat aaagattgcc tatatgacaa gatacaaagg gctgtgattg
     5281 gaagaggtgc tcatcctgaa ttgattcacg ataccttgct tggcaagtta aatgtttttt
     5341 taaagacgtt gaaaagctgg cgtcgatacg ctaagctagg gtcgttgtat gacttgattt
     5401 ggaaaatttt taatgatcgt ttttattttg attttgtagc tagtcaagca aaagcagaac
     5461 aagcacaagc taatctatac gcattagctc tacgtgctaa tcagtttgaa aaatcgggct
     5521 ataaagggct ataccgtttt attaaaatga ttgataaggt acttgagacg caaaatgact
     5581 tagctgatgt ggaagtggct actcctaaac aagctgttaa tttaatgacc attcacaagt
     5641 ctaaaggttt acaatttccg tatgtattta tccttaattg tgacaagcgc ttctcaatga
     5701 cagatattca taaatcattt attctgaatc ggcagcacgg tatcggtatc aagtaccttg
     5761 cagatatcaa aggtttactt ggtgaaacaa cactcaattc tgttaaagta agcatggaaa
     5821 ccttacctta tcaattgaac aaacaagagt tgcgcttagc aactttatca gaagaaatgc
     5881 gcttactgta tgttgctatg acacgagctg aaaaaaaagt ttattttatt ggtaaagcta
     5941 gtaagagcaa aagtcaagaa atcacagatc ctaaaaagtt aggcaaactt ttgccgctgg
     6001 ctttacgaga acagttattg acattccaag attggctatt agcaatagca gatatatttt
     6061 caactgaaga tctttatttt gatgttcgct ttattgaaga tagtgatttg acacaagagt
     6121 cagtcggacg acttcaaaca ccacagttat taaatccaga tgatcttaaa gataatcgtc
     6181 aatcagaaac aattgcacgg gctttagata tgttagaagc agtgtctcaa ttgaatgcca
     6241 attatgaagc agctattcat ttgccaacag ttcgaacgcc tagccaactt aaggcaactt
     6301 acgagccttt attagaaccc attggtgtag atattataga gaaatcttct cgatcgctat
     6361 ctgattttac tttgccacat ttttcaaaaa aagcaaaagt tgaagcaagt catattggat
     6421 cagctcttca tcagttgatg caggtgctcc ctttgtcaaa accgataaat caacaaacgc
     6481 ttttagacgc tttaagagga attgatagta acgaagaggt aaaaacagct cttgatctca
     6541 aaaaaataga gtcgttcttt tgtgatacaa gcctaggcca attttttcag acttaccaaa
     6601 aacacttgta tcgagaagcg ccatttgcta ttttaaaact tgaccctatc agtcaagaag
     6661 agtatgtcct acgtggtatt atagatgcct actttttgtt tgatgatcat attgtattag
     6721 tggactataa aacagataaa tacaagcagc ccattgagtt aaaaaagcgt taccaacaac
     6781 agttggagtt atatgcagaa gctctcactc aaacgtataa acttcctgtg actaagcgct
     6841 atcttgtttt aatgggaggt ggaaagccag aaattgtcga agtttaaggt tgttgtgaca
     6901 caagggtatt ttgcaaatga taatagtata gttgaggatt ttacgaaatg cttgaaaagc
     6961 tattgacctt tgaataataa tacaatataa taagttttat tagcgacaaa aaggaataaa
     7021 tatactatga attttaaaaa aataagattt ggttttttgc tttgcctcct actttatcct
     7081 ttagcagctt gtaacaagtc tgaacaactt aatcactacg aaagaattaa aaaaacaaga
     7141 aaattagtcg ttgctgtaag ccctgattat gctccttttg aatttaaagc tttagttaat
     7201 ggaaaagata ctattgttgg agcagatgtt caattagctc aggctattgc tgatgaatta
     7261 gacgttgatc ttgagctttc accaatgagt tttgataatg ttttgtctag tttacagact
     7321 ggtaaagctg atcttgctat ttcaggaatc tcacatacta aagaaagagc taaagtatat
     7381 gatttttcaa ttccttacta tcaggcagaa aacgctatag tgatgagagc atctgatgct
     7441 aaagtgacca aaaatattag tgacctaaac ggtaagaaag tagccgctca aaaaggtagt
     7501 atcgaggaag gtttagttaa aatacaatta ccaaaggcca atctgatttc tttgactgct
     7561 atgggagaag ccattaatga actaaaagca ggacaagtct atgcagttac cttagaagca
     7621 cctgtagctg ctggtttttt agcccaacat aaggatctgg ctttagcacc ctttagctta
     7681 aaaaccagtg atggagatgc caaagcagtg gcccttccta aaaatagtgg agacttaacc
     7741 aaagccgtta ataaggttat tgctaagtta gatgagcaag aacggtacaa gtcatttatt
     7801 gcagagacaa tagcactaac gaaaaatact atgaagtaat aaggttaata aaaactttat
     7861 tagtatccgt tggaaaagtg tttggaataa acaataaaag aggtttgact tttttaaaaa
     7921 aataatgtaa tataattggg aacgtgaaaa tgttacaata tcttgaggag gtgaaacaca
     7981 tgtcaaaaac agtagtacgt aagaatgaat ctcttgacga tgctcttcgt cgcttcaaac
     8041 gttctgttac taaagctggt actcttcaag aatcacgtaa acgtgaattc tacgaaaaac
     8101 cttctgtaaa acgtaaacgt aaatcagaag cagctcgcaa acgtaaaaaa ttctaatgga
     8161 taaaaaataa aacagttctc acaattagaa ctgtttttat tttttatcca gaagaagcaa
     8221 gggagctttt ttgatatcaa aaaaagtagt tagacatgcc taactacttt atcaaaaatc
     8281 gctttatttt tgagccaaca aatcacggat ttctgtcaat aattcttctt gagtaggagc
     8341 tgcagcttct ttttcctttt taggcatagc tttttcagcg gcttttacaa caaagaaaag
     8401 actggtaccg atgataagaa aattaataac ggctcctaaa aagctaccat atttaacacc
     8461 attccatgac aattgagtga tgttttcaac atttgcagct ttcaaagctg ggtttaaaat
     8521 aagcggtgtg ataatatcgt tcacaaaaga agtgacaata gcaccaaaag ctcccccgat
     8581 gataactgct acagcaagtt caataatgtt tcctctaaac aaaaatgctt ttaattcttt
     8641 aaccattaaa cattccccct ttttaatatc tctaagttaa gcatagcata attagtaaac
     8701 aaaatccaat ggaatcactt cagtttttaa atttacaaaa aagagtttcg gtggtataat
     8761 aaaacgtaaa actaaaatgg gatttttatg gggaggtgac gatttggcaa ttgacaaaga
     8821 aatgatttcc caagtaaaaa atagcgttaa tattgtcgat gtcattggag aagtggtcaa
     8881 actttcccga tcagggcggc attatctcgg gctttgccca tttcataagg aaaagacacc
     8941 ctcttttaat gttgttgaag acagacaatt ttttcactgc tttggctgtg gaaaatcagg
     9001 ggatgttttt aaatttattg aggaataccg ccaagtcccc ttcttagaaa gtgttcagat
     9061 tattgccgat aagactggta tgtcgcttaa tataccgcca agtcaggcag tacttgctag
     9121 ccaacacaag caccctaatc acgctttgat gacacttcat gaggatgctg ctaaatttta
     9181 ccatgcagtt ttgatgacca ctaccattgg tcaagaagct aggaagtacc tttaccagag
     9241 aggcttggat gaccaattaa ttgagcattt caatattggt ttagccccag atgagtcaga
     9301 ttatctttat caagctcttt ctaaaaaata cgaggaaggt caattggttg cttcaggatt
     9361 gtttcacttg tccgatcaat ccaataccat ttacgacgcc tttcgaaatc gtatcatgtt
     9421 tcccttatca gatgaccgag ggcatattat tgccttttca ggacgtatct ggacggcagc
     9481 tgatatggaa aagagacagg caaagtataa aaattcaaga ggaacagttc tttttaacaa
     9541 atcttatgaa ttgtatcatc tggacaaggc aaggcctgtt attgccaaaa cccatgaagt
     9601 gtttctaatg gaagggttta tggacgtgat tgccgcttac cgttccggct atgaaaatgc
     9661 tgttgcttca atggggacgg cattgactca agaacatgtc aatcacctta agcaagtcac
     9721 taaaaaagtt gttttgattt atgatggtga cgatgctgga caacatgcta ttgcaaaatc
     9781 actagaattg cttaaagatt ttgttgtcga aattgtcaga atccccaata aaatggatcc
     9841 tgacgaattt gtacaacggc attccccaga agcatttgca gatttgctta agcagtcacg
     9901 gatcagtagt gttgaatttt ttattgatta cctaaaacct actaatgtag acaatttgca
     9961 atcacaaatt gtttatgtgg agaaaatggc accattgatt gctcaatcac catccatcac
    10021 agctcaacat tcgtatatta acaagatttc tgatttgttg ccaaactttg actattttca
    10081 agtagaacaa tcagtaaatg cattaaggat tcaagatagg caaaaacatc aaggtcaaat
    10141 agctcaagcc gtcagcaatc ttgtgacctt accaatgcca aaaagtttga cagctattgc
    10201 taagacagaa agtcatctca tgcatcggct cttacatcat gactatttat taaatgaatt
    10261 tcgacatcgt gatgattttt attttgatac ctctacctta gaattacttt atcaacggct
    10321 gaagcaacaa ggacacatta catcttatga tttgtcagag atgtcagagg aagttaaccg
    10381 tgcttattac aatgttttag aagaaaacct tcccaaagaa gtagctcttg gtgagattga
    10441 tgatatttta tccaaacgtg ccaaactttt agcagagcgc gatcttcaca aacaagggaa
    10501 aaaagttaga gaatctagta acaaaggcga tcatcaagcg gctctagaag tactagaaca
    10561 ttttattgcg cagaaacgaa aaatggaata gaggaaatta tgacaaaaca aaaagaaata
    10621 acaactttta acgttcaagt tgcggagttt attcgccatc acaaaaaaga aggaacagcg
    10681 attgatgatg acgtgaccga aaaacttgtc attccatttg ctttggatgc tgatcagatt
    10741 gatgacttac ttgagcggtt aacagatggt ggtatctcga ttacggataa agaaggtaac
    10801 ccatcatcaa aatacattgt tgaagaacca aaaccagaag aattaactga tgaagaatta
    10861 attggtagta attcagctaa agtaaacgac cctgtccgca tgtacctcaa agaaattggt
    10921 gtggtaccgc ttttaacaag tgaagaggaa aaagaattgg ctgttgcggt tgccaaggga
    10981 gatttaatgg ctaaacaacg tttaacggaa gcaaaccttc gtcttgttgt ctcaattgca
    11041 aaacgttatg ttggacgtgg aatgcaattt cttgatttaa ttcaagaagg taacatggga
    11101 ctcatgaaag ctgttgataa atttgattat tcaaaaggat tcaaattctc aacttatgca
    11161 acatggtgga ttcgtcaagc tataacacgc gcaattgcag atcaagcacg tacgattcgt
    11221 atccctgttc atatggttga aaccattaat aaattggttc gtgaacaacg taaccttctt
    11281 caagaacttg gtcaagatcc aacgccagaa caaatcgcag aacgtatgga aatgactcca
    11341 gacaaggttc gtgaaattct aaaaattgct caagaacctg tttctttaga aacaccaatt
    11401 ggggaagaag atgatagtca cttaggtgat tttatcgaag atgaagttat tgaaaatcca
    11461 gtagattata cgacgcgtgt tgttcttcgt gagcaattgg atgaagtttt agatacgctt
    11521 actgaccgtg aagagaacgt tcttcgccta cgctttggcc ttgacgatgg taaaatgcgt
    11581 acgttagagg acgtaggtaa agtctttaat gttactcgtg agcgcattcg acagattgaa
    11641 gctaaagccc ttagaaaact tcgccatcct agtcgtagta aacaattaag agactttata
    11701 gaggactaaa atcgtccagt ggacgatttt aggtcgttcc tttgaaataa gaaaggagcg
    11761 aaaatcctaa gtggcactta tcagcggtac acctacaaat tagaaatcgg accgaatgtg
    11821 gtgggtattt ttaagggtag acttgatatc ttaaacaagc ccagaaggca attcctctaa
    11881 ataggcaaag ctttagtggt ttttttactt atctacgaca tattcaaaaa atgaaaggaa
    11941 agccatgtct gatacaccaa aatatacaca agatcaggtg atagctatca agaatagaat
    12001 tcttgaagct ttagaaactg ttattgatcc cgagctaggt attgatgttg ttaatctagg
    12061 cttgatttat gaaattcggt ttaatgataa cggttataca gagattgata tgacactcac
    12121 aacaatgggt tgtcctttgg cagacttgtt gacagattac atccatgatg ccctgcaaga
    12181 tgtgccagaa gtcactaaga ctgaggtcaa attagtctgg taccctgctt ggacggttga
    12241 taaaatgagc cgctatgcta ggattgcgct gggtattcgc taatcattga tagtaaaggg
    12301 atgaaatatt cccttttttg atgtagaata aaaggaaata caggtgaaag cctttggtta
    12361 atgttagaga acactaagat actgagaaaa gtgttctacc tatggcaaaa aggagaactg
    12421 atgattttaa ttacaggaag caatggtcaa ttagggacag aacttcgata cttattagat
    12481 gaacgaggtg ttgattatgt agccgttgat gtcgcagaaa tggacatcac aaatgaagac
    12541 aaagtcgaag ctgtttttgc gcaggtcaag ccaacattgg tctatcattg tgctgcttat
    12601 acggcagttg atgcagcaga agacgaagga aaagccttga atgaggctat taatgtaaca
    12661 ggctcagaaa atattgccaa ggcttgtgga aaatatgggg ctacccttgt ttacatttca
    12721 acagactacg tatttgatgg caataaacca gtcggtcaag aatgggtaga aacagatcat
    12781 ccagacccta agacagaata tggccgtaca aaacgtttag gagaactagc tgttgaacga
    12841 tacgcagagc atttttatat tatccgtact gcttgggtat ttggaaatta tggtaaaaac
    12901 tttgtcttta ccatggagca gttagcagaa aatcactccc gtttgactgt tgtcaatgac
    12961 caacacggtc ggccaacgtg gacaaggacc ttggcagaat tcatgtgtta tttgacagag
    13021 aatcaaaaag cctttggtta ctatcacttg tcaaatgatg ctaaggaaga caccacttgg
    13081 tatgattttg ccaaagaaat cttaaaagac aaggctgttg aagtggtgcc agttgattca
    13141 tcagctttcc cagcaaaagc caaacgtcct ttaaattcaa ccatgaatct tgataaggca
    13201 aaagcaacag ggtttgttat tccaacatgg caagaagcct tgaaggcatt ttaccaacaa
    13261 ggactgaaaa agtaagtatt ctaaaaagag ttggctttct aaggccaact ctttttcatg
    13321 ggtttaaggt cgcattagcc ttctaattgt ggtataatat cactgattat attttagaat
    13381 ggggtagtat gcaatgcagg atgtttttat cattggtagc agagggttac cagcgaaata
    13441 cggtggcttt gaaacctttg tcgaagagtt gattagtcat caatcatcta aaaacattcg
    13501 ttatcatgtt gcttgtttaa gcgatacgaa gcataaggtt cattttgatt ataagggggc
    13561 agattgcttt taccttaatc ccccaaaact tggtcctgct agagttattg cttatgatat
    13621 gatggcaatt acctatgccc tgtcttatag cgaccaacac cagattcaga accctatttt
    13681 ttatgtgttg ggcaatactg taggcgcttt tattgcgcca tttgtgaagc agattcacaa
    13741 tcgaggtgga cgctttttta tcaatccaga cgggttagag tggaaacggt ctaaatggtc
    13801 aagaccagtg caggcctacc tgaagttttc cgaaaagcaa atgactagac aggctgattt
    13861 ggtcatttca gataatattg gcattgaccg ctaccttaaa caagtttatc cttggtctaa
    13921 aacatgtttt attgcttatg gaacgcagac acaaccttca cgtttggcaa cagcagatag
    13981 caaggtcaga gcttattttc aaacctttga tattagagaa aaggattact atctcatttt
    14041 aggacgcttt gttcctgaaa ataattacga aaccgctatt aaagaattta tggcttcctc
    14101 aactaagcgt gatttagtga ttatttgtaa tcatgaaggc aatgcttact ttaagcaatt
    14161 acttgctgag acagagtgtg ataaagaccc acgcattaaa tttgttggta ccctttatga
    14221 caaagaacta ttagcctaca ttcgagaaca ggcttatgcc tatatccatg gtcatgaggt
    14281 aggagggact aatccaggcc ttctagaagc actagcccat accaatctta atttggtttt
    14341 aggagttgat tttaaccagt cggtggctaa gtctgctgcg ctttattgga ccaagcaaaa
    14401 agggcaatta gcagagctga ttaaccaagt tgatgcaggt tttgatagtg atcatctggg
    14461 caaagaagcc aaagctatta ttcaagaaca ttacacttgg gaaaaaattg taggggagta
    14521 cgaggcttta tttttaaatg aacattaata ttttactatc cacctacaat ggagaacgct
    14581 tcttagcaga acaaattcaa agtatccaaa ggcaaacagt taacgactgg accttattga
    14641 ttagagatga tggttcaact gatggcaccc aggatattat tcgcacattt gtcaaggaag
    14701 acaaacgaat tcagtggatc aatgaggggc agacagaaaa tctgggagtt attaagaatt
    14761 tttacaccct cttaaagcac caaaaagcag atgtctattt tttcagtgac caagatgata
    14821 tatggttaga caataaactg gaagtgacct tattggaggc tcaaaaacat gaaatgacag
    14881 ctcctttatt ggtttataca gacctcaaag tggtaaccca acatttagct gtttgccatg
    14941 acagtatgat taagacccaa tctggtcatg caaacacaag cctacttcaa gaattaaccg
    15001 aaaataccgt aacaggcggc acaatgatga ttactcatgc tctggctgag gaatggacca
    15061 cttgtgacgg tttattgatg catgactggt atttagcttt actagcttct gctattggga
    15121 aattagttta ccttgatatt ccaacagaat tataccgtca gcacgatgct aacgtgttgg
    15181 gagctagaac ttggtctaaa cgcatgaaaa attggttaac cccccatcat ttagtcaaca
    15241 aatattggtg gttgattact tcaagccaaa aacaggctca attactatta gatttaccat
    15301 taaaaccaaa tgaccatgaa ttggtaacgg cctatgtttc tttattggat atgcctttta
    15361 ccaaacgctt agctaccttg aaaaggtacg gttttagaaa aaatcgcatc tttcacacct
    15421 ttatttttcg tagtttagtt gttaccttat ttggttacag gagaaagtaa gaatgaattt
    15481 tttaacaaag aaaaaccgta ttttactgag agaaatggta aaaacggatt ttaaattacg
    15541 ctatcaaggg agcgcaattg gctatctatg gtctatctta aaaccgctta tgatgtttac
    15601 gattatgtac ttggtattta ttcgttttct tcgcctgggt ggaaatgtac ctcattttcc
    15661 agtagcgctt ttattggcaa atgtcatctg gtcttttttt tcagaagcaa ctagcatggg
    15721 aatggtatct attgtatctc ggggagactt gttgcgaaaa ttgaactttt ctaagcacat
    15781 cattgttttt tcggcagtgt taggagcttt aattaatttt cttattaatt tggttgttgt
    15841 tttaattttt gcgttgataa atggtgtgac tatatcaggg tatgcttatc tctctctttt
    15901 tctttttata gaattagttg ttttagtgct tggaattgca ttgttattgt cgaatgtctt
    15961 tgtttattat cgtgacttag ctcaagtctg ggaagtacta ttacaagcag gtatgtatgc
    16021 cactccaatc atttatccga tcacttttgt tttagatagc caccctttgg cggcaaagtt
    16081 gtcgatgcta aatccagtag cacaaatgat tcaagatttt cgttatttat tgattgacag
    16141 ggccaacgta acgatttggc agatgtcaac caattggttt tacattgtta ttccatattt
    16201 agtaccattt gttatattat ttattggcat ctttgtcttt aagaaaaatg ccgatagatt
    16261 tgcggagatt atttaatgat taatagagaa attgcagtaa aagtacagca tgttagtaaa
    16321 acgtttaaac tgcctacaga agcaactaaa agttttcgca cgactctggt taatcgccta
    16381 agagggatta aaggatttac tgaacaacat gtgctaaaag atattaactt tgatgtttat
    16441 aaaggcgatt tttttggaat tgttgggcgt aacggctcag gaaaatcaac gctccttaaa
    16501 attatttccc agatctatgt tccagaaaaa gggcaggtta cagtagatgg gaagatggtt
    16561 tcttttatag agcttggagt gggattcaat ccagaattaa caggacgaga aaacgtctat
    16621 atgaacggcg ccatgctggg atttaccaaa gacgaagttg atgatatgta caatgatatt
    16681 gttgattttg cagagttgca tcattttatg aatcaaaaat taaaaaatta ttcttctggc
    16741 atgcaggtac gtttagcatt ttcagtggct attaaagccc aaggtgacgt tcttatttta
    16801 gatgaggtgc ttgctgtagg agatgaagct tttcagcgaa aatgtaatga ttattttatg
    16861 gaaagaaaag acagtggtaa gacgactatt ttagtgacac atgatatggg agctgttaag
    16921 aagtattgta accgtgcagt tcttattgaa gatggtcttg ttaaagcata tggagaacca
    16981 tttgatgttg ctaatcagta tagtgtagat aatacagaga cagctgagga tgcaatgaat
    17041 gctgaaaaaa tatctgtatc tgatattgcc aaagatttga aagtgtcatt aatctcaaat
    17101 ccaagaataa caccaaatga cacaatcaca tttgaagttt cttatgaagt tttaaaagat
    17161 gattttacct acattgcctt ttctttaacg gatattgata gaaacatttg ggtttacaac
    17221 gacaattctt tagattatcc aacacaaggt ataggtagaa aatgcatttc ctaccaatgt
    17281 caactatctc aacttaatga tataaaacta aaattagaag taactgtccg agataagaac
    17341 ggtcagatgc tactcttttc aacagcagaa caatcacccc agatagtgat tcaaagaaac
    17401 gatattgatc aagatgatct gtcagctcta gattcagcaa gtggcttgta tcaacgtaat
    17461 gggaagtggg tttttcatta atgagtaata gctagaaggg aatttatgta taaagtttca
    17521 attatttgca ccaattataa caaagctcct tggatatctg atgcacttga cagtttttta
    17581 agccaagtga cagattttga ggttgaaatt attgttattg atgatgcttc tacagatgac
    17641 tcacgagaga ttttaaagag ttatcaaaaa aagtcttcag gaaaaattaa attactcttt
    17701 aacgaaacta atattggaat aacaaagact tggataaaag catgccttta tgcaaaaggc
    17761 aaatatattg ctagatgtga tggtgatgat tactggacgg atagttttaa actccaaaaa
    17821 caagttgatg tcttagaagc ttccaaacgg tcacgatggt gtaatactga ttttgacttt
    17881 gtaaatagtc aaggcgactt attatatgct aatgcttttt catctggtca tacacctttg
    17941 acagatactt acgaaaaagt tttagcctta aaagggatga cgatggcatc gacatggtta
    18001 gttgatgctg atttaatgag acaagtaaac caaaaaatca atgtagatac accagacgat
    18061 acttttgata ttcaactaga gttatttcaa ctgactcaac tgacctatat taaagactca
    18121 acgacgattt atcgcatgac aaccgattct gattcaagac ctactgatac accaaaaatg
    18181 atttatcgta ttcaaaaact acttgatact cagttaaatt acttaaaaaa gtataatcag
    18241 gtagatacaa aagaagtgtc tgaactatta ttacaacaag atgctaagca agaaatacga
    18301 attcatgagt tgagttgctt tattcaagaa ttacaacaaa ctatcgtaga taaaacaaag
    18361 cagcaagaaa cacgtgaagt ggagttgcaa aatgtcatag aagaacaaaa aaatcaacta
    18421 tctgaattaa gacaacaata ccatgccatt attaattcac gtcaatggaa atacacgtct
    18481 aagctcattg cttttattag gagaaaaaaa tgaatcgtat tttattatat gttcacttca
    18541 acaaatacaa taaaataagt gcacatgttt actatcaatt ggaacaaatg agatcactgt
    18601 tttctaagat tgtttttatc tcaaatagta aagtgagtca cgaagattta aaacgtctca
    18661 aaaaccactg tcttattgat gagtttttgc aacgcaaaaa taaaggtttt gatttttctg
    18721 catggcacga tggcttgatt attatgggat ttgacaagtt ggaagagttt gactcattga
    18781 cgattatgaa cgatacttgt tttggtccta tttgggagat ggctccttat tttgaaaatt
    18841 ttgaagaaaa agagacagtt gacttttggg gaattactaa taatagaggt acaaaagctt
    18901 ttaaagaaca tgtccaaagt tattttatga cgtttaaaaa tcaagtcatt caaaacaaag
    18961 tttttcaaca attttggcaa tcgataatag aatatgaaaa cgttcaagaa gtgattcagc
    19021 attatgaaac gcaattaaca tccattctct taaatgaagg ctttagttat cagacggtct
    19081 ttgatactag aaaagctgag tcgtcattca tgccacatcc ggatttttca tattataatc
    19141 caacagcaat tttaaaacac catgtgcctt ttataaaagt aaaagctatt gatgctaacc
    19201 agcatatcgc tccttactta ttgaatctga tacgagaaac aaccaattat cctatagatc
    19261 ttattgtttc acatatgtcg caaatctctt tgccagatac taagtacctt ttatctcaaa
    19321 aatacctaaa ctgccaacgg ttagcaaaac aaacttgtca aaaggtagct gttcatttac
    19381 atgtttttta cgttgatttg ctagatgaat ttttaacagc tttcgaaaac tggaacttcc
    19441 attatgatct ttttattaca acagatagtg atatcaaaag aaaagagatc aaagaaatac
    19501 ttcaaagaaa aggtaaaact gctgatatac gcgttacggg aaatagagga agagatattt
    19561 atccaatgtt attactaaaa gataaacttt ctcaatatga ttatattggt catttccata
    19621 cgaaaaaatc aaaagaagct gatttttggg caggagaatc ttggcgaaaa gaattgattg
    19681 atatgctcgt gaaaccagca gatagtattc ttagcgcttt tgagacagat gatattggta
    19741 ttataatcgc agatattcca agttttttta gatttaataa gattgtcaat gcttggaatg
    19801 agcatttaat cgctcaagaa atgatgtctt tgtggagaaa aatggatgtt aaaaaacaaa
    19861 ttgattttca agctatggat acatttgtta tgagttatgg aacatttgta tggtttaaat
    19921 acgatgctct aaaatcactt tttgatttag aattaactca aaatgatatt ccaagtgaac
    19981 ctttaccaca aaactctata ttacatgcga ttgagcggtt acttgtctat atagcgtggg
    20041 gggattctta tgattttagg attgttaaaa atccctatga gttaacacct tttattgaca
    20101 ataaactgtt aaatttacgt gaagatgaag gagctcatac ctacgttaac tttaatcaaa
    20161 tgggcggtat caaaggagca ttgaaatata ttatcgttgg tcccgctaaa gcaatgaagt
    20221 atatattctt gcgtttaatg gagaaactta aatgattaaa gacacatttt taaaaaccaa
    20281 ttggttaaat attagtcacc atattatcct tcttgttttc ggtttttatt tcagttttta
    20341 cagtttggcg aaagaactag taagctccac ggcacaaccg gtaaactatt atgctcattt
    20401 actaaatgtt tcttttgtgg gatatattat atcactgatt ggattatctt attatttgag
    20461 tcgccaagtt agtcgacagt tgtttttgaa aactagtttt attgtgatat cttatctaat
    20521 tgtcagctat tgggtacaaa taacacagca cctgaatgat aaacggtttg atatctggtc
    20581 attaactaaa aatcaatttt atcaatttca agctctacct tctttactca ttattttagt
    20641 gatggccact ttaataaaaa tattggtagc atattttgca atagaaaaag atagatttgg
    20701 gctattaggc tatcaaggta atactttttc tgtagctctg attttagcag ttgtgccaat
    20761 taatgacata catctgttaa aactaataag ttctcgattt tctgaattag taacagcagg
    20821 taatagccaa attgcactgt taaaaataag tggactgttg atagttttac ttgtcatatt
    20881 tgcaacaatc atatacgtgg ttttaaatgc tctaaaacac cttaagtcaa ataaaccttc
    20941 attttcagta gcagctacta ctagtttgtt tttagcatta gtttttaact atacgttcca
    21001 gtatggagta aaaggtgatg aagcattgct aggatattat gttttccctg gagctactct
    21061 ttttcagata gtagctatta cactagttgc tcttttagca tacgtgataa cgaatagata
    21121 ttggccaact accttctttt tgcttattct gggaacaatt atttctgttg ttaatgattt
    21181 aaaagaatca atgagaagcg agccgttatt agtaactgat tttgtttggt tacaagaatt
    21241 aggtttagtg acaagctttg ttaaaaaatc ggtgattgta gaaatggttg taggacttgc
    21301 tatttgtatt gtggtagctt ggtatctaca tggccgagtt ttagcaggga aattatttat
    21361 gagccctgtc aaacgggcaa gtgctgtatt aggtttattt attgtatctt gtagtatgtt
    21421 aataccattt tcttatgaaa aagaaggtaa aatattatct ggtcttccga ttatttcggc
    21481 tttaaataat gataatgaca taaactggtt aggtttttca acaaatgcta ggtacaaatc
    21541 tttagcatat gtttggacaa gacaggtgac caagaaaata atggaaaaac cgacaaatta
    21601 tagccaagaa acaatagcga gtatcgctca gaagtaccaa aaattagcag aagatattaa
    21661 taaagacaga aaaaataata ttgctgacca aacggttatt tatcttttaa gtgaaagctt
    21721 gtcagatcct gatagagtat caaatgttac tgttagccac gatgttttac ctaatatcaa
    21781 ggcaatcaaa aatagcacaa ctgcgggact catgcagtca gactcctacg ggggtggaac
    21841 ggctaacatg gagtttcaaa cgttaacaag cttacctttt tataattttt cttcttcagt
    21901 atctgttctt tattcagaag tctttcctaa aatggccaaa cctcatacga ttagtgagtt
    21961 ttaccaagga aaaaatcgta ttgcgatgca tcctgctagt gctaacaatt ttaatagaaa
    22021 aacagtttat agtaatttag gtttttccaa attcttagct ctatcgggtt ctaaggataa
    22081 gtttaagaac attgaaaatg tcggtttatt gactagcgat aaaactgtct ataataatat
//
LOCUS       DAUGJR010000031        21544 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUGJR010000031 DAUGJR010000000
VERSION     DAUGJR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21544
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.031"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            29..1288
                     /gene="hasA"
                     /locus_tag="VH800_001243"
     CDS             29..1288
                     /gene="hasA"
                     /locus_tag="VH800_001243"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HEQ8362317.1"
                     /translation="MPIFKKTLIILSFIFLISILIYLNMYLFGTSTVGIYGVILITYL
                     VIKLGLSFLYEPFKGKPHDYKVAAVIPSYNEDAESLLETLKSVLAQTYPLSEIYIVDD
                     GSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFERSDADVFLTVDSD
                     TYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRLTDIRYDNAFGVERAAQSL
                     TGNILVCSGPLSIYRREVIIPNLERYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQS
                     TARCDTDVPFQLKSYLKQQNRWNKSFFRESIISVKKILSNPIVALWTIFEVVMFMMLI
                     VAIGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMIKHPASFLLSPLYGILHLFV
                     LQPLKLYSLCTIKNTEWGTRKKVTIFK"
     gene            1324..2532
                     /gene="hasB"
                     /locus_tag="VH800_001244"
     CDS             1324..2532
                     /gene="hasB"
                     /locus_tag="VH800_001244"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEQ8362318.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2714..3628
                     /gene="hasC"
                     /locus_tag="VH800_001245"
     CDS             2714..3628
                     /gene="hasC"
                     /locus_tag="VH800_001245"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEQ8362319.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     GILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
     gene            3936..4349
                     /gene="yaaA"
                     /locus_tag="VH800_001246"
     CDS             3936..4349
                     /gene="yaaA"
                     /locus_tag="VH800_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEQ8362320.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIITIVEPSQEEKEQFAEEMAEKTRVAALVKQMNQANKK
                     TSSKHNNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            4351..5457
                     /gene="recF"
                     /locus_tag="VH800_001247"
     CDS             4351..5457
                     /gene="recF"
                     /locus_tag="VH800_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEQ8362321.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDELAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(5512..6375)
                     /locus_tag="VH800_001248"
     CDS             complement(5512..6375)
                     /locus_tag="VH800_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEQ8362322.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
     gene            complement(6577..8058)
                     /gene="guaB"
                     /locus_tag="VH800_001249"
     CDS             complement(6577..8058)
                     /gene="guaB"
                     /locus_tag="VH800_001249"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEQ8362323.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
     gene            complement(8366..9388)
                     /gene="trpS"
                     /locus_tag="VH800_001250"
     CDS             complement(8366..9388)
                     /gene="trpS"
                     /locus_tag="VH800_001250"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEQ8362324.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQIGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     misc_binding    complement(9443..9684)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9807..10679
                     /locus_tag="VH800_001251"
     CDS             9807..10679
                     /locus_tag="VH800_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8362325.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     gene            10758..12377
                     /locus_tag="VH800_001252"
     CDS             10758..12377
                     /locus_tag="VH800_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8362326.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            12460..15036
                     /locus_tag="VH800_001253"
     CDS             12460..15036
                     /locus_tag="VH800_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ8362327.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVILGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLRLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPIKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPPNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEMRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(15533..15606)
                     /locus_tag="VH800_001254"
     tRNA            complement(15533..15606)
                     /locus_tag="VH800_001254"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15570..15572),aa:Asn,seq:gtt)
     gene            complement(15640..15711)
                     /locus_tag="VH800_001255"
     tRNA            complement(15640..15711)
                     /locus_tag="VH800_001255"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15676..15678),aa:Glu,seq:ttc)
     gene            complement(15906..16670)
                     /locus_tag="VH800_001256"
                     /pseudo
     CDS             complement(15906..16670)
                     /locus_tag="VH800_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            16835..16908
                     /locus_tag="VH800_001257"
     tRNA            16835..16908
                     /locus_tag="VH800_001257"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16869..16871,aa:Arg,seq:tct)
     gene            complement(17065..17544)
                     /gene="rlmH"
                     /locus_tag="VH800_001258"
     CDS             complement(17065..17544)
                     /gene="rlmH"
                     /locus_tag="VH800_001258"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEQ8362328.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            17756..18979
                     /locus_tag="VH800_001259"
     CDS             17756..18979
                     /locus_tag="VH800_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEQ8362329.1"
                     /translation="MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            19038..19844
                     /locus_tag="VH800_001260"
     CDS             19038..19844
                     /locus_tag="VH800_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEQ8362330.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            20077..21432
                     /gene="dnaA"
                     /locus_tag="VH800_001261"
     CDS             20077..21432
                     /gene="dnaA"
                     /locus_tag="VH800_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEQ8362331.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
BASE COUNT         7129 a         3889 c         3583 g         6943 t
ORIGIN      
        1 ggaaattaaa aaagaaagag gtgtaattgt gcctattttt aaaaaaactt taattatttt
       61 atcctttatt tttttgatat ctatcttgat ttatctaaat atgtatctat ttggaacatc
      121 aactgtagga atttatggag taatattaat aacctatcta gttattaaac ttggattatc
      181 tttcctttat gagccattta aaggaaagcc acatgactat aaagttgctg ctgtaattcc
      241 ttcttataat gaagatgccg agtcattatt agaaactctt aaaagtgtgt tagcacagac
      301 ctatccgtta tcagaaattt atattgttga tgatgggagt tcaaacacag atgcaataca
      361 attaattgaa gagtatgtaa atagagaagt ggatatttgt cgaaacgtta tcgttcaccg
      421 ttcccttgtc aataaaggaa aacgccatgc tcaagcgtgg gcatttgaaa gatctgacgc
      481 tgacgttttt ttaaccgtag attcagatac ttatatctat ccaaatgcct tagaagaact
      541 cctaaaaagc ttcaatgatg agacagttta tgctgcaaca ggacatttga atgctagaaa
      601 cagacaaact aatctattaa cgcgacttac agatatccgt tacgataatg cctttggggt
      661 ggagcgtgct gctcaatcat taacaggtaa tattttagtt tgctcaggac cattgagtat
      721 ttatcgacgt gaagtgatta ttcctaactt agagcgctat aaaaatcaaa cattcctagg
      781 tttacctgtt agcattgggg atgatcgatg tttaacaaat tatgctattg atttaggacg
      841 cactgtctac caatcaacag ctagatgtga tactgatgta cctttccaat taaaaagtta
      901 tttaaagcaa caaaatcgat ggaataaatc tttttttaga gaatctatta tttctgttaa
      961 aaaaattctt tctaatccca tcgttgcctt atggactatt ttcgaagtcg ttatgtttat
     1021 gatgttgatt gtcgcaattg ggaatctttt gtttaatcaa gctattcaat tagaccttat
     1081 taaacttttt gcctttttat ccatcatctt tatcgttgct ttatgtcgta atgttcatta
     1141 tatgatcaaa catcctgcta gttttttgtt atctcctctg tatggaatat tacacttgtt
     1201 tgtcttacag cccctaaaac tttattcttt atgcaccatt aaaaatacgg aatggggaac
     1261 acgtaaaaag gtcactattt ttaaataata tgtgcatcga gtagttagag aaggagtaat
     1321 tttatgaaaa tagcagttgc tggatcagga tatgttggat tatcactagg agttctttta
     1381 tcacttcaaa acgaagtcac tattgttgat attcttccct ctaaagttga taagattaat
     1441 aatggcttat caccaattca agatgaatat attgaatatt acttaaaaag taagcaatta
     1501 tctattaaag caactttaga tagcaaagca gcttataaag aagcggaact ggtcattatt
     1561 gccacaccta caaattacaa cagtagaatt aattattttg atacacagca tgttgaaaca
     1621 gttatcaaag aggtactaag cgttaatagc catgcaactc ttatcatcaa atcaacaatt
     1681 ccaataggtt tcattactga aatgagacag aaattccaaa ctgatcgtat tatcttcagc
     1741 cctgaatttt taagagaatc taaagcttta tatgacaact tatatccaag ccgaattatt
     1801 gtttcttgtg aagaaaacga ttctccaaaa gtaaaggcag acgcagaaaa atttgcactt
     1861 ttattaaagt ctgcagctaa aaaaaataat gtaccagtac ttattatggg agcttcagaa
     1921 gctgaagcag taaaactatt tgccaatact tatttagcgt taagggtagc ttattttaat
     1981 gagttagaca cttacgcaga atcgagaaaa ttaaatagtc acatgattat tcaaggaatt
     2041 tcttatgatg atcgaatagg aatgcattat aataacccat catttggtta tggaggttat
     2101 tgtctaccta aagatacgaa gcaattattg gcaaattaca ataatattcc tcaaacgcta
     2161 attgaagcta tcgtttcatc aaataatgtg cgcaagtcct atattgctaa gcaaattatc
     2221 aacgtcttag aagagcggga gtccccagta aaagtagtcg gggtttaccg tttaattatg
     2281 aaaagtaact cagataattt tagagaaagt gctatcaaag atgttattga cattcttaaa
     2341 agtaaagaca ttaagataat tatttatgag ccaatgttaa acaaacttga atctgaagat
     2401 caatctgtac ttgtaaatga tttagagaat ttcaagaaac aagcaaatat tatcgtaact
     2461 aatcgctatg ataatgaatt acaagatgtt aaaaataaag tttacagtag agatattttt
     2521 aatagagact agccatgtct tcatctataa caataatatt catttttact ttaaaagaac
     2581 tgcagttggt ggtatgattg agcactatga aatagtcgaa aaatcatatg aaaacgtaac
     2641 atgatgtcaa atgaattccg ttctgaaaac gaatgtcact aagccataga ttataaaaag
     2701 tgaggagtta ctgatgacca aagtcagaaa agccattatt cctgctgcag gtctaggaac
     2761 acgtttttta cctgctacca aagctcttgc caaagagatg ttgcccatcg ttgataaacc
     2821 aaccatccag tttatcgtcg aagaagcgct aaaatctggc atcgaggaaa tccttgtggt
     2881 gaccggaaaa gctaaacgct ctatcgagga ccattttgat tcaaactttg aattagaata
     2941 caacctccaa gctaagggga aaaatgaact gttgaaatta gtggatgaaa ccactgccat
     3001 taaccttcat tttatccgtc aaagccaccc aagagggctg ggagatgctg tcttacaagc
     3061 caaagccttt gtgggcaatg aaccctttgt ggtcatgctt ggagatgact taatggacat
     3121 tacaaatgca tccgctaaac ctctcaccaa acaactcatg gaggactatg acaagacgca
     3181 tgcatccact atcgctgtga tgaaagttcc tcatgaagat gtgtctagct atggggttat
     3241 cgctcctcaa ggcaaggctg tcaagggcct ttacagtgta gacacctttg ttgaaaaacc
     3301 acaaccagaa gatgcgccta gtgatttggc tattattggt cgttacctcc taacccctga
     3361 aatttttggt attttggaaa gacagacccc tggagcaggt aacgaagtgc aactcacaga
     3421 tgctatcgat accctcaata aaactcagcg tgtctttgca cgagaattta aaggcaatcg
     3481 ttacgatgtt ggggataaat ttggattcat gaaaacatct atcgactatg ccttagaaca
     3541 cccacaggtc aaagaggact tgaaaaatta cattatcaaa ctaggaaaag ctttggaaaa
     3601 aagtaaagta ccaacacatt caaagtaatg tgttggtact ttactttttt ccttgtttat
     3661 agcaacttaa gtttatatct tgaaaattgt caacgttcca aaatataaaa gttttgtgtt
     3721 atacaacttt actagaggga catattaata ataggattta tacgtagaaa aatgataaac
     3781 ataagtacag cttttgttaa aactaattaa caagaacttc aaaactaaat agttatttgg
     3841 acgagtatga tactttataa atagctctta ttcagctatt attatttatt tctgttttat
     3901 gctataatga cttgaatgac aaaatggaga tgacaatgat atacaaatta tttacagaat
     3961 ttatcaccct acaagccctt cttaaagaat taggaattat ccaaagtggt ggcgctatca
     4021 agggatttct cgctgaaaca accgttctat ttaatggtga agatgagaaa cgtcgaggca
     4081 aaaaaatcag agtaggggat aagatttctc tacctgacca agacttaatt atcactattg
     4141 ttgagcctag tcaagaagaa aaagaacaat ttgccgaaga aatggctgaa aagacacgtg
     4201 tagcggctct agtgaaacaa atgaaccaag ctaacaaaaa gacttcttct aaacataaca
     4261 atcgtcaatc tactaccaaa aaatcactaa gagcaactaa gaaaactaaa ggtaaaccaa
     4321 ctgcacctgt ccgcttccca ggtatctagt atgtggatta aagagttaga gttaaaacat
     4381 tatcgcaatt atgaccacct gcttgcctca ttttcgtcgg gtttaaatgt ctttatcggt
     4441 aataatgctc aaggaaaaac caattttctc gaggcaatct attttctatc acttactaga
     4501 agtcatcgca cgagggctga taaagaattg attcattttg atcactcaac tgtttctctt
     4561 actggtaaga ttcagcgtat tagtggtact gttgatttag aaatcaatct atcagataaa
     4621 ggacgtgtga caaagattaa tgcgctaaag caagcaaaat tatctgatta tattggaacg
     4681 atgatggttg tgctttttgc accagaagat ttgcaactag ttaagggagc acctagcctt
     4741 cgtcgcaaat ttatcgacat tgaccttggt caaattaagc ctgtttactt atctgagtta
     4801 tcccattata accacgtgct taaacagcgt aatagctatt taaaaagtgc ccaacaaatt
     4861 gatgccgctt ttctagctgt tctagatgag caattagcta gctatggagc ccgtgtcatg
     4921 gaacatcgta ttgattttat caatgcgtta gagaaagaag caaatactca tcaccaagcc
     4981 atctcaaatg gtttagaaag tctctctctc tcctatcagt cgtcagttgt ctttgacaaa
     5041 aaaactaata tttaccaaca atttttacac caacttgaaa aaaatcatca gaaagatttc
     5101 ttccgtaaaa acactagcgt tggtccacat cgcgatgaat tagcctttta cattaacggg
     5161 atgaatgcta actttgctag tcaaggtcag caccgcagcc ttatcctttc cttaaaaatg
     5221 gctgaagtta gtttaatgaa ggccttgact ggagataatc ccattctttt actagacgat
     5281 gtcatgagcg agctagacaa tacacgacaa acaaagttac ttgaaacagt aattaaagaa
     5341 aatgtccaaa cctttatcac aacaacaagt ttggatcacc tgtcacagtt gccagaaggt
     5401 atccgtattt ttcacgtgac aaaaggaacc gttcaaattg attctgatat tcactaataa
     5461 catcaaaaaa gggttcagtt aaactgagcc ttttttgata ttatgtggcg attaagattt
     5521 gaccacacct aataaaatag cacctacgat aaaacaaata attcctgtga caacccaacg
     5581 catttctttt ttggttttgg tttcgcctag gaataaaatg cctccgacaa tcgaaatgat
     5641 agcacctaat tgtgagaaac taaaggcaat agcaagtcct gcttttgatg cagctaaaag
     5701 cataaaaata ttcccaatgc cccaaagtaa tccaacaacg ctatttttaa tcacatactg
     5761 gtcaatggaa attttaaatg acatgaaagt tatagctcct aaaaccatac ctactgccat
     5821 gggtaaaatg actgacaaaa cttcaaattt catgatgtta ttaaataata cagcatacat
     5881 cacgtaacca attgttgaat aagtgagcgc cctaaatcct tttgaaaaat tatgaaggtg
     5941 attgacttgt gcattagcat catcttgttt actagaaaag taaaaaccaa caatcagaag
     6001 taatagtgct agacttccta ctacaaattg cataggtctt gtccattcat gaaaaacgag
     6061 gacaccaatc aaacttccca gaacaagttg agagccactt gacaaaggat tggcaacgga
     6121 gactcccatg tattgcatgg catgaaattg accagtttga ccaattgacc agataaaacc
     6181 acccaatatt ccaaaaagcc aaagttgcag tgtcatctca ggtctaacaa ttaaccaaac
     6241 agctaatgaa aataataaag ccccaaaagt cattcctaga gtttgttgcg aaggttttcc
     6301 tccaattttg ttactaacaa atccaatgct tccccatgta aacatgggaa taagtgcata
     6361 aaaaatacct tccaaaatgt tatctccttt atagtaaatc tttaaagatt ataataattc
     6421 catcataaaa tggtttcatg taaagactaa ttatagctta tttactaaga aaaaacaata
     6481 aaagttatcc gaaaattgtt attatatttt atcatttttt aatataaaaa agagctggca
     6541 caatatgtca gcccttaaag ttactaaatt aaattatcag tgcacagaat agtttggtgc
     6601 ttcatttgtg atttggacat catgtggatg actttcaatc aagcctgcac ctgacatttc
     6661 aacaaattga gcattttcat gtaattcttg aatgtcacct gcgccaacat agcccatacc
     6721 tgagcggata ccacctaaca tttggaagac aatatctgaa gcagctcctt tataagcaac
     6781 acggccttca ataccttctg gaactagctt attagcttca ttgacggaac cttggaagta
     6841 acgatcgctt gatcctttct tcatagctgc aatggaaccc attccacgat aagttttgaa
     6901 cttacggcct tggtagattt cagtttcacc tggagcttca tcagtacctg caaacattga
     6961 tccaagcata acagcattac cgccggctgc aagagcctta acaatatcgc cagaatactt
     7021 gataccacca tcagcaataa tcgttttgcc atattcacga gcaacagcag cagcatcgta
     7081 aatagcagtc acttgaggaa caccgacacc tgcaaccaca cgagtggtac agatagatcc
     7141 gggaccaata cccactttaa caacatcaac acctgcatca taaagagcac gcgcaccttc
     7201 agcagtggca atatttccag caatcaaagt acgatttggg aaatgagcac gaatttcagc
     7261 aattttacga agaacaccag ccgaatgacc atgagctgtg tcaataacaa tcgcatctgc
     7321 accagcttca aacaaggcct cggcacgctc aaaagtatct gaggtaacac ctaccgcagc
     7381 agcgaccaga agacgaccaa attcatcttt agcagcatgt gggaattcga ttactttttc
     7441 aatatctttg atagtgatta aaccagacag acgaccgcta ttatcaacca aaggaagttt
     7501 ttcaatacgg tgttcatgaa gaatacgttc tgcagtttca agatctgtac caacagcagc
     7561 cgtaacgagg tgctcactag tcatatgttc agagattggt gcattgtaat cagaaataaa
     7621 acgcatatca cgattagtaa tgataccgac caacttacgg tttgctaaag tttcaacaat
     7681 tggcacacca ctgatacggt agcgctgcat taattcttca gcttctgaaa ccttgtgttc
     7741 aggtgttaag aagaatggat caatgatgac accattttca gaacgtttta ccttgcgaac
     7801 ttcttctgct tgctcagtaa tagacatgtt tttatgaata acacctaaac cacccgcacg
     7861 cgcaattgca atagccattt tactaccagt aaccgtatcc atagctgctg taataatagg
     7921 aatatttaat gtcaaattgt ctgcgagttt tgtctttaaa tcaacttcat ttggaagaac
     7981 atgactctct gccggaataa gcaagacatc gtcaaaagtg tagccttttt tcaaaaattt
     8041 agtgtcccaa tttgacatcc agataatcct cttttctttt atttttaggg aatattaccc
     8101 tggtctattt tttattgtta ctatcatatc acgctaaaat catttgtcaa taaaatattc
     8161 ctacagctga agtcactatc agcataatat atcagtatta tccgtttttt attaatcaaa
     8221 aaattcattt gggtcttatt tttaatcaaa aataagacta tataaaacat aatctctact
     8281 atcctgtaaa gaaatgacaa attaggtcct gttttgataa tagtaattat cttatcatta
     8341 ctaacttagc tttttctcta aaacattaaa aataattaat acccattgct gacttcactt
     8401 ctgataaagt cttggctgcc acagttcttg ctttttgact accttcttgt aacatacgga
     8461 acacctctcc catatcttta gcgtactcca aacgtctttc acgaataggt gctaattcac
     8521 gttctaaaat atctaaaagg tagcgtttcg ttttcacatc tcctaaacca cctatttgat
     8581 aatgctcttt cattgcttcg atatcagctt gatcttcttt tctagcaaaa atatccaaat
     8641 aatgaaagac catattccct tcaatttgac caggatcttc tattttaata tgatttggat
     8701 cagtatacat gctcatcact tttttgcgaa cggtatctgc atcatctgag agatagattc
     8761 catttcccaa tgacttagac attttggcat tgccatcaag accaggtaag cgtccagctt
     8821 tttcattttc tggataaata ccttcaggtt ctactaaaca gtctgtatgg taagtatgat
     8881 taaaacttct cacaatttca cgtgtttgtt caatcatcgg tttctggtcg ttacctacag
     8941 gtactaaatt cgctttaaat gctgtaatat cagcggcctg tgatactgga taaaccaaaa
     9001 aaccagatgg aatactttcg ccaaaacctt tctgagcaat ttcggtttta acagtgggat
     9061 ttctttccaa acgtgctaat gataccagat tcatataata catgctcaat tcagctagct
     9121 ctggaatctg actttgaata aaaatcgttg attgcttcgg atccaaaccg acagagaggt
     9181 aatccaaggc aacatttcca atagattctt gaattaattc ggattcttta gcatgatccg
     9241 tcagtgcctg ttgatcggcc aagaaaacaa acatcttata cttgttttca ttttgtaaaa
     9301 agacacgatt tttaagactt ccgacataat gacctaaatg taattttcca gttggtctat
     9361 ctccagttaa aataataggt tttgtcatca ttttctccct aactatctct tgatatagca
     9421 aaaagtcccc acgctattaa aacgtgaggg cgttattaca agtaatacgc ggtaccacct
     9481 caattagcat ctgctttatc aaaacgagat actatctcaa tcttctcaat gaaagaagct
     9541 gcacggtaag gggtgccaac ctgaaagtta tggtttcctt tcaaataatc attagtccat
     9601 ttcacctttt ctgttgttag cttgcaccaa ccactaactc tctaaaaaca tgaaaagaat
     9661 actcttctaa tttagattta ttctatgaaa ttttaaactt cttgtcaagt tcaccagatt
     9721 ttttgaaaat atgacttgac ggtctcagta catttaagag ataatgagtc tactattttt
     9781 aaccagttat aaaggagatt aaaagcatga aaaaacgagg gattgattta ctacttgtca
     9841 caattggctc attcataaca gctattggtt tcaatacaat gtttgtcgac aatcatattg
     9901 catcaggggg tatggttggt attgcagttg ttataaaagc tctatttggc attagtccgt
     9961 cgcttttttt aatggctagt aatattccct tattattaat gtgttacttc tttcttggaa
    10021 aacaaaattt tattaaaaca ctttatggtt cttggatata tcctattgcc atccgttcaa
    10081 ccaattcatt acctactctg acacacaatc agttgttagc agctattttt ggtggtatta
    10141 tctgtggcat tggtttagga atggtttttt ggggaaactc ttcgacagga ggaactggaa
    10201 ttctaacaca aatacttcat aaatactctc ctttatctct tggagttgca atgacaattg
    10261 tagatggtat tagtgtcctt atgggattta ttgcactttc tgcagatgac gtgatgtatt
    10321 ctacgattgg acttttcgta attggttatg tgattagcgt tatggaaaat ggctttgact
    10381 catccaaaaa tgttatgatt atttccaaag attatcaagc tattcgagaa tatatcacaa
    10441 ctgttatgga tcgtggagtg actaaacttc ctattcgcgg tggttatact acttctgata
    10501 aaattatgtt aatggctatt gtatcaagtc acgaattacc tactctccaa gaaaaaatcc
    10561 tcgaaattga cgatacagcc tttattgttg tcatgccagc agctcaagtt atgggaagag
    10621 gatttagttt gactaaacaa tacaaacgtg aagacaaaga cgttttattg cctatgtagt
    10681 gattagccct tttctgattg aaaaagggga ctattttagg tacaatgaag cttagataaa
    10741 taaaatgagg tgacaaattg cttacagttt ctgatgtatc actacgcttt agtgatcgaa
    10801 aactatttga tgatgttaat atcaaattca cagccggcaa tacttacggc ttaatcggtg
    10861 ccaatggtgc cggaaaatca acttttctta aaatccttgc aggagatatt gaaccaagta
    10921 ctggtcatat ctctttagga cctgacgaac gcttatctgt tcttcgccaa aatcattttg
    10981 attatgaaga agaacgtgcg attgatgttg taatcatggg taatgaacaa ctctacaata
    11041 tcatgaaaga aaaagacgct atctatatga aagcagattt ttcagaagaa gatggggttc
    11101 gtgccgctga gctagaaggt atctttgctg aattaggtgg ctgggaggca gaaagtgaag
    11161 cttctcaact tctccaaaat ctaaatattc cagaagacct tcactaccaa aatatgagtg
    11221 aactggctaa tggagataaa gtgaaagtcc ttcttgctaa agcgctcttt ggtaagcctg
    11281 acgttttatt acttgacgag ccaaccaatg gtcttgatat tcaatctatt tcatggttgg
    11341 aagatttctt gattgatttt gaaaatacag tcatcgttgt ttcccatgac cgtcacttct
    11401 tgaataaagt atgtactcac atggccgacc ttgactttgg taaaatcaaa ctctttgtgg
    11461 gtaactacga tttctggaaa caatcttctg agctggccgc tcgtttacaa gctgaccgca
    11521 atgctaaagc agaagagaaa atcaaagaat tacaagaatt cgttgcccgt ttctcagcaa
    11581 acgcatctaa atcaaaacaa gcaacctctc gtaaaaaaat gcttgataag attgaattag
    11641 aagaaattgt tccctcaagc cgtaaatacc catttattaa ttttaaagca gagcgtgaaa
    11701 tgggaaatga cttcctcact gttgaaaatc tttctgtaac gatcgatgga gagaaaatca
    11761 ttgataatat cagtttcatt ttacgtccag gtgacaaagc tgctattatt ggtcaaaatg
    11821 atattcagac aactgctctt atgcgtgctt tagcagatga tattgactac gaaggaacca
    11881 ttaaatgggg agtgacaaca agtcgttctt acttgcctaa agacaattca aaagattttg
    11941 ccacggaaga atctattctt gaatggttac gtcaatttgc ctcaaaaggt gaagatgatg
    12001 ataccttttt acgtgggttc ttaggacgga tgcttttctc tggagacgaa gttaaaaaat
    12061 ctgttaacgt tctttccggt ggcgaaaaag tgcgtgtcat gctttctaag ttgatgctat
    12121 tgaaatcaaa cgttcttatt cttgatgacc caactaatca cttagatttg gaatctattt
    12181 caagtcttaa tgatggaatc aaagacttca aagaatctgt tatctttgcc agtcatgacc
    12241 atgaatttat tcaaacgatt gctaaccaca tcgttgttat ttcaaaaaat ggtgttatcg
    12301 accgtataga tgaaacttat gacgaattcc ttgacaatcc agaagtccaa gcccgagttg
    12361 ctgaactttg gaaataaaac cttatgataa atgaggtggc taagaagatc tcttcctagc
    12421 ctctttttta aaatttgtaa acgaaagacc atataattta tgaaaaataa taataaatgg
    12481 ataattgctg gacttgctag ttttttgttc cctcttagta ttatatttat catccttcta
    12541 tcgatgggca tttattataa tagtgataaa acaattctag ctagtgatgc ttttcatcag
    12601 tatgttattt ttgcgcagaa ctttcgtaac atcatgcacg gttctgatag ttttttttat
    12661 acctttacaa gcggactagg gataaatttt tatgctttaa tgtgttatta tcttggcagt
    12721 ttcttttctc cattactttt cttttttaat ttaacctcta tgccagatgc tatctatttg
    12781 tttaccttga taaaatttgg gttaatagga ttagctgcat gctattcttt tcatagatta
    12841 tatccaaaaa tcagtgcttt cttgatgatt tccatctcag ttttttatag cttaatgagc
    12901 ttcttgacaa gtcaaatgga actaaattct tggttagatg ttttcattct tcttccactt
    12961 gttatacttg gattaaataa acttatcaca gaaaataaaa ccagaactta ttatctttcg
    13021 atatcattat tattcattca aaattactac tttggctaca tgattgctct tttttgtatt
    13081 ctttacgcct tagtttgtct tttacgtctc aatgatttta acaaaatgtt tatcgctttt
    13141 gttaggttta cagctgtgtc aatatgtgct gctttaacaa gtgctctagt aatacttcct
    13201 acctatctag atttgtcaac ttatggagag aatctatccc cgataaaaca gttagttacg
    13261 aacaatgctt ggtttttgga tatacctgct aagctctcaa taggagtgta cgatactacc
    13321 aagtttaatg ctctgcctat gatttacgta ggattatttc ccctaatgct tagtgttatt
    13381 tattttactt tagaaagtat ccctttaaaa ataaaattag ccaatgcctg cttgttaact
    13441 tttattataa taagttttta cctacagcca cttgatcttt tttggcaggg gatgcactca
    13501 ccaaatatgt ttttgcatcg ctacgcttgg tctttttcca tagttatcct attactcgca
    13561 tgtgagactc tctctcgact aaaagaagtg actcaaataa aagcaggttt tgcttttatt
    13621 ttcctcatta tactgacatc tcttccttat agcttttctc aacaatataa ttttctacct
    13681 ttaactcttt ttttacttag tgttttttta ttattaggtt atactatttc actattttcg
    13741 tttagaaatt ctcaaatccc atctactttt atttctgctt tcatacttat ctttagcctt
    13801 cttgaatcag ggttaaacac ctactaccag cttcaaggaa ttaataagga gtggggattc
    13861 ccatcacgac agatatataa tagtcaatta aaggatatta acaaccttgt caactctgtg
    13921 tcaaaaaata gtcaaccttt ttttagaatg gaaaggctac ttccccaaac agggaacgat
    13981 agcatgaaat ttaattatta cggcatttca caattttcct ctgtaagaaa tagactatct
    14041 agttctttat tggatcgatt gggatttcag tctaaaggca caaatttaaa ccttagatac
    14101 caaaacaata ctattattat ggacagtcta cttggtataa aatataatct tagcgaagga
    14161 cctccaaata aatttggatt tacaaaacta aaaactagcg ggaatactac tctttatcaa
    14221 aatcactata gtagcccttt agctatatta acacgtaatg tttacaaaga tgtcaaccta
    14281 aatgtcaata cccttgataa ccaaaccaaa ttacttaacc aactaagtgg gaaatcttta
    14341 acctatttta acttacagcc agctcaactt atttctggtg ctaatcaatt taacggacaa
    14401 atatctgcac aagcttctga ttatcaaaac tccgttaccc ttaattatca aattaacatc
    14461 cctaaacata gtcaactcta tgttagcata cccaatatta tattttcaaa tcctgatgct
    14521 aaagagatgc gtattcagac agataatcat aatttcatat atactacaga taacgcttac
    14581 tctttttttg atttaggata tttcgccgat gccaaagttg ctacattttc gtttgttttt
    14641 ccaaaaaata aacaaattag ttttaaggaa cctcattttt atagtttgtc tattgaatct
    14701 taccttgaag caatgaatag cattaaacaa aaaaatgttc atacttacgc taaaagtaat
    14761 acggtaatca ctgattataa ttcaaaaacg aaaggttctc ttatttttac acttccttac
    14821 gataaaggtt ggtcagcaca aaaagatggg aaaaatcttc cagtcaaaaa agcacaagga
    14881 ggatttctat cagttactat tcctaaagga aagggacgtg ttatccttac ctttattcct
    14941 aatggtttta aattagggtt atctctatct tgtgtaggaa ttatcgctta tatgcttttg
    15001 tataagtaca tagatataaa gtctaaatta ctttagtccg aaaaaatcag atttttttat
    15061 caatttggca aatgagtcaa tatactaaaa gtatctcaag agctagacaa atattctaat
    15121 acttgagatg cttttatcga ttttactaat aaactcaaat aatataaagg tcagattttt
    15181 cgtgagggtt aatgttaaac tactctcttt caaagattga aatgacaata atcatcgctg
    15241 atacgatttc aatcttttga ctccttacaa taatcttata ttcatcagta ttgaatggga
    15301 gacatgcttt caaaatgtaa aaaattaagc ttcagttaat gtttgtaatt aaacttaatg
    15361 ttatcatcta tacaattaaa gaacagaact tctattttaa tgcaaaatac aatcctgtta
    15421 gttcacaatg ctgtatttag tggtttaata attagtaaat tgagcatttg acctgagtat
    15481 ctgttttact aaataaaaaa atcctaagat tatcttagga aatatcttat cactccggca
    15541 gtaggactcg aacctacgac atcatgatta acagtcatgc gctactacca actgagctat
    15601 gccggaaaaa gaaaaaaatt gccaaaatga caattgcgat agtccgtacg ggattcgaac
    15661 ccgtgttacc gccgtgaaaa ggcggtgtct taaccccttg accaacggac cagaagtttt
    15721 ggaggatatc tccttaacac tcttactatt atagcagatt gatttttttt gtctatactt
    15781 ttttaaaaaa aatttgattt tttttaaacc gcaagttgtc aagtcaagtg caacgagttc
    15841 atagataact agagttccag aggttaagct gttcgggata gctcaaacag gaattttgag
    15901 gattgctatt gaagaagtcg tcttaggcgc tcattgatgg cagtaatatc attgtcaagt
    15961 tcttcagagg ttagtggatt aagtgagatt cctttaggga catattctct gaggagacca
    16021 ttgaagttct cgtttgttcc tctctcatgt gaagaatagg gatgtgcaaa gtaaacgtca
    16081 acagctttta agtctgagag taaactaaac tcagaaccat tatccgctgt gatggatgca
    16141 ataggatact gactgatgag atgcgtgaca gcacggttaa tggtttggga ctgcttgtct
    16201 tctatagtgc atagcgtgtc tggcgctcta ccaaagtcaa cataacagct tcacttttgg
    16261 ttttcttgcc gagagccaaa tcaatctccc aatgcccaaa ttcagaacga tcattaatat
    16321 attctggacg ttcttcgata gatttaccta aagtcttctt attcgtcttc atgactttct
    16381 tagaacgttt tctgatacta accatcttag acaaatctat tggtttcata gacacgttgt
    16441 ctactatcag cgaaataggc gttgaagaag gtttgttttc cattcttatc ctttacctga
    16501 tctactgaac cacgttttat ttctcggcag attgtagaac ggtgactacc cagaagtcga
    16561 gcaatctcaa cgggtttctt tcccatttta agataagcag caatttcacc ccgttctgtg
    16621 gctgaaagat gagaatagga tgattttctg gtagaattaa tattagacat gttcatctgc
    16681 tttccatact gaattgggga attctagtat atcagacgaa catgtctttt ttgttgtact
    16741 tcattttata acgcgggata taatgttatt ttctagtttt ttcaaaataa atattgacag
    16801 ttttagataa tttttgttaa aatgatgtgg ttaaggtctc atagctcagc tggatagagc
    16861 attcgccttc taagcgaacg gtcgcaggtt cgaatcctgc tgggatcaaa gataaaaaag
    16921 cactgtttta gtgctttttt tgtatttacc ttagtgtatt gaaaagatag gatttagtac
    16981 gtcttttttt aatatttgct tttaattata ccgaactatt atctaataaa gtggtaagag
    17041 ttagttattc cagttcacac tctcttactt atgataagga ctgccttgtg taatcataaa
    17101 agcacgataa atttgctcag taaggactag acgcattaac tgatgaggta aggttaacaa
    17161 tccaaaactc attagcatat tagctctttt tttaataatt gaatctaatc caagactccc
    17221 accaataata aacgtgatag ttgaatatcc cttaacagta acccctgata ttaattcact
    17281 aaatgtctct gaaggaaact gttttccttc aatagctaat gcaattacaa aatcacgttc
    17341 cccaattttt ttatggattc gctgagcttc tttactcata atcaattgat tatcagcaaa
    17401 acttgcttta tctggtgttc tttcatcagt taactcaatc atttcgaatt gacaaaaacg
    17461 ggaaagtctt ttttgatatt ctgaaatacc atctttgagg tatctttctt ttagttttcc
    17521 aacacaaatt agtttcactt tcatagctta attgtatcac aagaacatta ctttttacac
    17581 aatttatcca caagttattt ttcttcaact actaataaaa acctttgtac aaaggtcttt
    17641 attagtaaaa agaaaagtaa tccacaggct gtggattact tttctttttt ttatttttaa
    17701 ggtataatta agcaaagttc tataagctat ggacaaataa ttcggaggac aaaacatgcc
    17761 aagtatgaaa catatcttaa aatccttaag tattttacta attggatttt taggaggatt
    17821 aatagcaatt attacattca ataatctcta cccacattct ccatcaaaaa taaattcagg
    17881 taaggcaaca actagtaata tggtttttaa caacacaacc aatactacta aagctgtcaa
    17941 agctgttcaa aatgcagttg tatcagttat taattatcaa gataaccctt cttcatccct
    18001 ttctaaccct tatacaaaac tctttggaga agggcgttca aaagagaata aggatgctga
    18061 attatctatt tttagtgaag gatctggggt catttatcga aaagatggca actccgctta
    18121 cgttgttact aataaccatg ttatcgacgg agctaaacga attgaaattc ttatggcaga
    18181 cggatctaaa gttgttggtg aattagttgg agctgatact tattcggatt tagctgttgt
    18241 taagatctct tcagataaga taaaaacagt agctgaattt gcagattcta caaaactaaa
    18301 tgttggagaa gttgctattg ctatcggcag cccactagga acacaatacg ctaattctgt
    18361 tactcaagga atcgtctcta gtttaagtcg tactgtaact ttaaaaaacg agaatggtga
    18421 gactgtctca acaaatgcta ttcagacaga tgctgctatt aaccctggaa actctggtgg
    18481 accactaatt aatattgagg ggcaagtaat cggaattaat tcaagtaaaa tttcttctac
    18541 cccaactggt agcaacggta atagtggtgc tgttgaagga attggttttg ctatcccatc
    18601 tactgatgtt attaaaatta ttaaacaact agaaactaat ggtgaagtta tcagacctgc
    18661 tcttggaata tccatggtca atttaaatga cttatccaca aatgctctta gtcaaattaa
    18721 tattccaact agtgtaactg gtggtattgt agtagcagaa gttaaggaag gaatgccggc
    18781 atctggcaaa cttgctcagt acgatgtgat tacagaaatt gatggcaaaa cagttaattc
    18841 aattagtgat ttacaaagta gtctatacgg acacgatatt aatgatacta ttaaagtaac
    18901 tttttataga ggaactacaa agaaaaaagc agatatcaaa ttaacaaaaa ctactcaaga
    18961 tttgactaaa acgcagtaaa caagctacct aaatactatt acattttatc acataaaaca
    19021 gtccaaagga ctgttttatg tttcttattc tatccaggaa ctcccttatg acaaaagaat
    19081 tattgataga cctaccaatt gaagatattg ttacaaatcc ctatcagcca aggatacaat
    19141 ttaatcaaag agaactccaa gacctagcaa cttctattaa atcaaacggc ctcattcaac
    19201 ctattattgt tcgaaaatct gacatttttg gctatgagtt agttgctgga gaacgacgac
    19261 ttaaagcttc aaaaatggct ggtctaaaaa aagttccagc tatcatcaag aagatctcca
    19321 cactcgagag catgcaacaa gctatagttg aaaatttaca acgttctaac cttaacgcta
    19381 tcgaagaagc taaagcctat cagttattgg ttgaaaaaaa acacatgact cacgatgaga
    19441 ttgctaaata tatgggaaaa tcaagacctt atattagcaa taccttacgt ctgttacaac
    19501 tcccagcacc tatcattaaa gcaattgaag aaggaaaaat tagtgcggga cacgcgcgtg
    19561 ctcttttaac tttgagtgat gataagcaac aactgtacct cactcataaa atacaaaatg
    19621 aaggcctaag tgttaggcaa attgagcaac tggttacttc tactccaagt tcgaagctat
    19681 ctaaaaaaac taaaaatatt tttgccactt ctttagagaa acaattggct aaatcattgg
    19741 gactctctgt caatatgaag ctgacagcaa accatagtgg gtaccttcag atatcttttt
    19801 ccaatgatga tgaattaaac agaattatca acaagctaaa gtagcttgtt gatattctgt
    19861 tttttctttt ttagttttcc acatgaaaaa tagttgaaaa caatagcggt gtccccttaa
    19921 aatggctttt ccacaggttg tggagaaccc aaattaacag tgttaattta ttttccacag
    19981 gttgtggaaa aactaactat tatccatcgt tctgtggaaa actagaatag tttatggtag
    20041 aatagttcta gaattatcca caagaaggaa cctagtatga ctgaaaatga acaaattttt
    20101 tggaacaggg tcttggaatt agctcagagt caattaaaac aggcaactta tgaatttttt
    20161 gttcatgatg cccgtctatt aaaggtcgat aagcatattg caactattta cttagatcaa
    20221 atgaaagagc tcttttggga aaaaaatctt aaagatgtta ttcttactgc tggttttgaa
    20281 gtttataacg ctcaaatttc tgttgactat gttttcgaag aagacctaat gattgagcaa
    20341 aatcagacca aaatcaacca aaaacctaag cagcaagcct taaattcttt gcctactgtt
    20401 acttcagatt taaactcgaa atatagtttt gaaaacttta ttcaaggaga tgaaaatcgt
    20461 tgggctgttg ctgcttcaat agcagtagct aatactcctg gaactaccta taatcctttg
    20521 tttatttggg gtggccctgg gcttggaaaa acccatttat taaatgctat tggtaattct
    20581 gtactattag aaaatccaaa tgctcgaatt aaatatatca cagctgaaaa ctttattaat
    20641 gagtttgtta tccatattcg ccttgatacc atggatgaat tgaaagaaaa atttcgtaat
    20701 ttagatttac tccttattga tgatatccaa tctttagcta aaaaaacgct ctctggaaca
    20761 caagaagagt tctttaatac ttttaatgca cttcataata ataacaaaca aattgtccta
    20821 acaagcgacc gtacaccaga tcatctcaat gatttagaag atcgattagt tactcgtttt
    20881 aaatggggat taacagtcaa tatcacacct cctgattttg aaacacgagt ggctattttg
    20941 acaaataaaa ttcaagaata taactttatt tttcctcaag ataccattga gtatttggct
    21001 ggtcaatttg attctaatgt cagagattta gaaggtgcct taaaagatat tagtctggtt
    21061 gctaatttca aacaaattga cacgattact gttgacattg ctgccgaagc tattcgcgcc
    21121 agaaagcaag atggacctaa aatgacagtt attcccatcg aagaaattca agcgcaagtt
    21181 ggaaaatttt acggtgttac cgtcaaagaa attaaagcta ctaaacgaac acaaaatatt
    21241 gttttagcaa gacaagtagc tatgttttta gcacgtgaaa tgacagataa cagtcttcct
    21301 aaaattggaa aagaatttgg tggcagagac cattcaacag tactccatgc ctataataaa
    21361 atcaaaaaca tgatcagcca ggacgaaagc cttaggatcg aaattgaaac cataaaaaac
    21421 aaaattaaat aacatgtgga aaagaatatc ttttatgaaa tagttatcca caagttgtga
    21481 acatccattt agtcttggat tctctcgttt atttagagtt atccactata tacacaagac
    21541 ctac
//
LOCUS       DAUGJR010000032        21385 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUGJR010000032 DAUGJR010000000
VERSION     DAUGJR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21385
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.032"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     repeat_region   129..362
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=129..164
                     /rpt_unit_seq="gttttagagctatgctgttttgaatggtcccaaaac"
     gene            475..882
                     /locus_tag="VH800_001262"
                     /pseudo
     CDS             475..882
                     /locus_tag="VH800_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            1006..2838
                     /gene="lepA"
                     /locus_tag="VH800_001263"
     CDS             1006..2838
                     /gene="lepA"
                     /locus_tag="VH800_001263"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEQ8362332.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK"
     gene            3096..3932
                     /locus_tag="VH800_001264"
     CDS             3096..3932
                     /locus_tag="VH800_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8362333.1"
                     /translation="MLTFGGASAVKAEENEKVREQEKLIQQLSEKLVEINDLQTLNGD
                     KESIQSLVDYLTRRGKLEEEWMEYLNSGIQRKLFVGPKGPAGEKGEQGPTGKQGERGE
                     TGPAGPRGDKGETGDKGAQGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKD
                     GQDGKDGLPGKDGQPGKPAPKTPEVPQNPDTAPHTPKTPRIPGQSKDVTPAPQNPSNR
                     GLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQE
                     NN"
     gene            4118..4555
                     /gene="msrB"
                     /locus_tag="VH800_001265"
     CDS             4118..4555
                     /gene="msrB"
                     /locus_tag="VH800_001265"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8362334.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            4670..5689
                     /locus_tag="VH800_001266"
     CDS             4670..5689
                     /locus_tag="VH800_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEQ8362335.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGLQKWLRLDVNTATLVGVGSSICGGSAVAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDVLHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            5896..6321
                     /locus_tag="VH800_001267"
     CDS             5896..6321
                     /locus_tag="VH800_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8362336.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            6340..6831
                     /locus_tag="VH800_001268"
     CDS             6340..6831
                     /locus_tag="VH800_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8362337.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            6848..7657
                     /locus_tag="VH800_001269"
     CDS             6848..7657
                     /locus_tag="VH800_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8362338.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            7654..8481
                     /locus_tag="VH800_001270"
     CDS             7654..8481
                     /locus_tag="VH800_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8362339.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            8617..10266
                     /locus_tag="VH800_001271"
     CDS             8617..10266
                     /locus_tag="VH800_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8362340.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRATHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLEVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            10270..11058
                     /locus_tag="VH800_001272"
     CDS             10270..11058
                     /locus_tag="VH800_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8362341.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEVTKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            11052..12098
                     /locus_tag="VH800_001273"
     CDS             11052..12098
                     /locus_tag="VH800_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8362342.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNVAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTNADAWAYMKRLLVNMNSIRATSSSEV
                     YQSVAEGKMIVGLTYEDPCINLQKSGANVSIVYPKEGTVFVPSSVAIIKHAPNMTEAK
                     LFINFMLSRDVQNAFGQSTSNRPIRQDAQTSHDMKALETIATLKEDYAYVTKHKKKIV
                     ATYNQLRQRLEKAK"
     gene            12195..12700
                     /locus_tag="VH800_001274"
                     /pseudo
     CDS             12195..12700
                     /locus_tag="VH800_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            12877..13443
                     /locus_tag="VH800_001275"
     CDS             12877..13443
                     /locus_tag="VH800_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEQ8362343.1"
                     /translation="MTTEFDKMTRGEWYDANFDSELIQKRMMAQDLCFDLNQLKPSRE
                     EERSAVLNQLFGQSFEGLVLLSPFICDYGKNITFGKNCFINSNCYFMDGAKIALGDNV
                     FVGPSTGFYTANHPLDYKRRNEGLEKALPITIGDNVWFGANVNVMPGVTIGSGCVIAS
                     GSVVTHDIPVNSLAAGVPCQVVRKIEQE"
     gene            13459..14148
                     /locus_tag="VH800_001276"
     CDS             13459..14148
                     /locus_tag="VH800_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEQ8362344.1"
                     /translation="MHYNFLFFDLDHTLLDFDAAEEVALTKLLEEYQVIDIKAYKDYY
                     KPMNQNLWKQLEGGDISKADLVNSRFALLFAHFGVTVDGRQLAEGYQKHLKDQGQVYA
                     GAKELLADLTAQGYNLYAATNGIATIQQGRLQASGLAPYFKAIFISEQSGSQKPKKAF
                     YDWMTQQVSNYQPDQALMIGDSLSADVQGGINAGMDTLWYNPKHLLNNSPVHPTYEVS
                     DYQALLNCIAE"
     gene            14243..15640
                     /locus_tag="VH800_001277"
     CDS             14243..15640
                     /locus_tag="VH800_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEQ8362345.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVNLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNGNTKV"
     gene            15742..17538
                     /gene="uvrC"
                     /locus_tag="VH800_001278"
     CDS             15742..17538
                     /gene="uvrC"
                     /locus_tag="VH800_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEQ8362346.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASKEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYTDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            17723..18325
                     /locus_tag="VH800_001279"
     CDS             17723..18325
                     /locus_tag="VH800_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEQ8362347.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            18450..19859
                     /gene="pepV"
                     /locus_tag="VH800_001280"
     CDS             18450..19859
                     /gene="pepV"
                     /locus_tag="VH800_001280"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEQ8362348.1"
                     /translation="MTTIDFKAEVDKRKKAMLADLVDLLRINSERDDQLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLDVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGLTKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(19927..21303)
                     /gene="mnmE"
                     /locus_tag="VH800_001281"
     CDS             complement(19927..21303)
                     /gene="mnmE"
                     /locus_tag="VH800_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEQ8362349.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIINPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLESLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
BASE COUNT         6491 a         3932 c         4575 g         6387 t
ORIGIN      
        1 tcttaataac taaaaatatg gtataatact cttaataaat gcagtaatac aggggctttt
       61 caagactgaa gtctagctga gacaaatagt gcgattacga aattttttag acaaaaatag
      121 tctacgaggt tttagagcta tgctgttttg aatggtccca aaacgggtgg ttggctgacg
      181 catcgcaata ttaagtttta gagctatgct gttttgaatg gtcccaaaac aggaatatcc
      241 gcaataatta attgcgctct gttttagagc tatgctgttt tgaatggtcc caaaactaaa
      301 tttgtttagc aggtaaaccg tgctttgttt tagagctatg ctgttttgaa tggtctccat
      361 tcaacattgc cgatgataac ttgagaaaga gggttaatac cagcagtcgg ataccttcct
      421 attctttctg ttaaagcgtt ttcatgttat aataggcaaa agaagagtag tgtgatggaa
      481 caaacatttt ttatgattaa gccatatggg gttaagcaag gggaggtagt tggagaggtt
      541 ttacggtgga ttgaacgcct aagatttacg tttaagcgat tcgagccaag acaagctagt
      601 tcgaaatact tggctaagca cgacgaggcc ttggtgataa accttttgat cctaaactta
      661 aagcttacat gacaagtggt cctgttttaa ttgggataat tcttggggac taaggtggtt
      721 ttgtcttttt gaaccatgat gagagtaacc aatcctaagg atgctctttg cggaaccatt
      781 cgtgagaatt ttgctcaggc tcctggtgat gatggaggta tttttaacat ggtgcatggg
      841 tctcattcaa gagactctgc taggcgtgag atcgctcttt gatctcatca aagtaatctt
      901 ggtagctccc ctattctctt gcaagataat ccgtaagaaa agataggcaa aggcctacct
      961 tttttgttat aatagaagga aagactaaat gtataggaaa atagaatgaa cagtcaagat
     1021 ttaaaaaaac gtcaggagaa gattcgtaat ttctccatta tcgcacatat tgaccatggc
     1081 aaatctactc tcgctgaccg cattttggaa aagacagaga cggtttcgtc tcgtgaaatg
     1141 caggctcagt tattggactc catggatttg gagcgtgagc gtgggattac catcaagtta
     1201 aacgccattg agcttaatta cacggctaaa gatggggaaa cctacatttt ccaccttatt
     1261 gataccccag ggcatgtgga ctttacttat gaagtatcgc gttcgttggc agcctgtgag
     1321 ggagcgattt tagttgttga tgcagcgcag ggaattgaag cgcagacatt ggctaatgtt
     1381 tacctagccc ttgataatga tttggaaatt ttaccggtta tcaataaaat tgatttgcct
     1441 gctgctgacc ctgagagagt ccgtcatgaa gtagaagatg tcattggact tgatgcttct
     1501 gaggctgttc tggcatcagc caaggctggt attgggatcg aagagattct tgagcaaatt
     1561 gttgagaagg ttcctgctcc tacgggtgat gtggatgcgc ctttacaggc cttgattttt
     1621 gactctgtgt atgatgctta ccgaggggta attttgcagg ttcggattgt gaacggtatt
     1681 gtcaagcctg gcgataaaat ccagatgatg tctaatggaa aaacctttga tgttacagaa
     1741 gttgggattt tcactcctaa ggcagttgga cgagatttcc ttgcgacggg agatgttggt
     1801 tatgttgcgg cttctatcaa aacggtagca gatacccgtg tgggggatac ggtgacttta
     1861 gctaataacc ctgctaagga agccttgcat ggctacaagc agatgaaccc gatggtcttt
     1921 gcagggattt atccgattga atcaaataaa tacaatgact tgcgtgaagc acttgaaaaa
     1981 ttacaactga acgatgccag tttacagttt gaacccgaaa cgtcacaagc gcttggattt
     2041 ggttttcgat gcggtttttt aggcttgctt cacatggatg tgattcaaga acgtttggaa
     2101 cgtgaattta acattgattt gatcatgaca gcaccatctg tagtctacca tgttcacaca
     2161 acagatgagg acatgattga agtgtctaac ccttcagaat ttccagaccc aacacgggtg
     2221 gcttttattg aagagcctta tgttaaagcg caaatcatgg tgccacaaga gttcgtaggg
     2281 gctgttatgg aattatcgca gcgcaagcgt ggtgattttg tgaccatgga ttacattgat
     2341 gataaccgtg tcaatgtgat ctaccaaatc ccgctggctg aaattgtgtt tgatttcttt
     2401 gataaattga aatcctcaac gcgaggctat gcgagttttg attatgacat gtcagaatac
     2461 cgcaggtcac aattggtgaa aatggacatt cttttgaacg gtgataaggt cgatgcgctc
     2521 agctttattg ttcataaaga atttgcttat gaacgcggga aaattattgt tgagaaattg
     2581 aaaaaaatca ttccacgtca acagtttgaa gttccgatcc aagccgctat tggtcaaaaa
     2641 attgttgcgc gttcagacat caaggccctt cgtaaaaacg ttttagcgaa gtgttatggt
     2701 ggtgacgtgt ctcgtaaacg taaattgctc gaaaaacaaa aggctggtaa aaaacggatg
     2761 aaggctattg gttctgtcga agtccctcaa gaagccttct tgagtgttct ttcaatggat
     2821 gacgatacca agaaataacc aagcctaatc gcttagtctt cagaggagaa ctcttgtggg
     2881 tctacatgac caaaaaatgg ttatcttata caaaaagaac tttacaatca ttcgcacata
     2941 atgttataat aatattataa tgttatctca ttattaggtg ggtctacatt taatattatt
     3001 aaagaaaaaa gaggaaacaa aaactgtgaa caaaacaaaa caaaacaaaa catagccttc
     3061 tttgtcgcta tggcttaacc tcagcggctg ctcttttgct gacctttgga ggtgcaagtg
     3121 cggttaaggc ggaagaaaat gaaaaagtaa gagagcaaga aaagctcata cagcaacttt
     3181 ctgaaaagct agtggaaatt aatgacttac aaactttaaa tggtgataaa gagagtatac
     3241 agtctctcgt agattatctg actcgaagag gaaaacttga agaagaatgg atggaatatt
     3301 tgaattctgg tattcaacgc aaactttttg ttggtccaaa aggacctgca ggtgaaaaag
     3361 gagaacaagg tcctactgga aaacaaggcg agcgtggtga gaccggccct gcaggtccac
     3421 gtggtgacaa gggcgaaact ggtgacaaag gagcccaggg tccagtaggt cccgctggca
     3481 aggacggcca aaacggtaaa gatggtcttc caggtaaaga cggcaaggac ggccaaaacg
     3541 gtaaagatgg tcttccaggt aaagacggca aggacggcca agatggcaaa gatggtcttc
     3601 caggtaaaga cggtcaacca ggtaaaccag ctcctaaaac accagaggtc cctcaaaacc
     3661 cagatactgc accacatact ccaaaaaccc ctcggatccc tggtcaatca aaagacgtga
     3721 cacctgctcc tcaaaaccct tctaatagag gtctaaacaa accacaaaca caaggtggta
     3781 atcagctcgc aaaaacaccg gcagctcacg acacacacag acaattgcca gcaacaggcg
     3841 aaacaaccaa tccattcttt acagcagctg ctgtagctat catgacgaca gctggagttg
     3901 tagctgttgc aaaacgtcaa gaaaacaact aatcctcttt ttgctaccta actgatggaa
     3961 agtaaaactc agagagaacc tcaaggttct ctcttttttg aatcaagata gtagctctag
     4021 gtataacgtc ttgtctgagg tgctgtgaac aaatcagtta ccgctcacct ctttttttgg
     4081 taaaatgtaa gcactaaaac atcaaaagga gttttccatg gaaacatcag atgagttaaa
     4141 acaacgcatt ggtgatcttt cttacgaggt cacccagcat gcagcaacag aatctccctt
     4201 tacaggagaa tatgataatt tttttgagaa gggtatctat gtcgatatcg tcagtggtga
     4261 ggtcttgttt tcatcactgg ataaatttaa ttctggctgt ggttggcctg ccttttcaaa
     4321 acctattgaa aatcgtatgg tcacaaacca cgatgactct tcttatggga tgagacgagt
     4381 tgaggttaaa agccgtgaag caggatcgca tttggggcat gtctttagtg acggccccaa
     4441 agaagctgga ggcttgcgtt actgtatcaa ttcagcagct cttaaattta ttccttatga
     4501 ccagatggaa aaagaaggct atgcccaatg gctcacattg tttgatgaga cataacaggg
     4561 tttcaaaatg actgaaattc ccacaagcac tggattggtg aggcgtacgg gtcagtttta
     4621 caagcctttg taaaaggtct ataataggga atgaaaaaag gaggttagta tgtcaactca
     4681 cttaagaaaa cttccagggc tgttactttg cttattgtta gctcttccag cctggtgttt
     4741 agggcgctta tttcccatta ttggagcacc tgtttttgct attcttttag gaatgttgtt
     4801 agccttgttt tatgaacatc gtgacaagac taaagaggga attagtttta catccaagta
     4861 tattttacaa acagcagtgg ttttgcttgg ttttggatta aacctaaccc aagttatggc
     4921 agtgggcatg cagtctttac cgattatcat ttcaactatt gcgacagctc ttttggtagc
     4981 ttatggctta cagaaatggc tgcgcttaga tgtcaataca gccaccttgg taggtgtagg
     5041 atcttccatt tgtggggggt ctgctgttgc agcgacagct cctgtcatta aggcaaagga
     5101 tgacgaggtt gctaaggcaa tttcagtcat ttttctcttt aatatgttag cagctttgct
     5161 atttccaagt ttaggacaat tactaggctt atctaatgaa ggttttgcta tttttgccgg
     5221 gacagctgtt aacgacactt cttccgtgac tgcaacggcc acggcctggg atgtccttca
     5281 ccattccaat acactagatg gagcaaccat tgttaaattg actcgcacct tggctattct
     5341 cccaattact ttaggtttat ccctttaccg agcgaaaaaa gagcacgaca tcgttacaga
     5401 agaaaacttt agccttagga agtcattccc tcgtttcatc ctcttctttt tattagcttc
     5461 tctcatcaca acattgatga ccagtttggg agtttctgcc gatagtttcc attacctaaa
     5521 aaccttatca aaattcttta tcgtgatggc tatggcagcg attggtttaa acacaaacct
     5581 ggttaaactg attaagacgg gcggtcaggc tatcctttta ggagctattt gctgggtagc
     5641 tatcaccctt gtcagtttag ccatgcaatt aagtttgggc atttggtaat cagacacgag
     5701 aaatcagttt gactgatttc tttttttgta tcttatttgt gtagaattgt ctacatttta
     5761 aagagaataa tgcattttta aaacgttttc atttgataaa ataaacctat cgttaaacca
     5821 gttcagtaag gacaactggt tgagataagc aattaccgtt tactcagcgg tttttgttaa
     5881 tagaggagga taggaatgaa acgaaaattt ctcattggga gtcacggcag actagccagt
     5941 ggtttgcaaa gctctattga cattttagca ggtatgggac aggcacttga aaccattgat
     6001 gcttatgttg atgatagtga ctacactagc cagattgatg actttatcgc tggggtagca
     6061 gcagatgagc agggccttat ttttactgat ttgttaggcg gcagtgtgaa tcagaaaatg
     6121 gtaaccgctg taatgaacag tggcaaagac aatatctttt taatcacaaa cagtaactta
     6181 gccactttat tgtcgttggt gtttttaaaa ccaggcgaag cgcttactaa agatgaaatt
     6241 gtaaccgtta tcaatgaatc gcaagttcag ttagtggatt tggtccctga gacaaattca
     6301 gaagatgact tttttgatta atatctagga ggaagacaaa tgattaccca aattcgtgtt
     6361 gacgaccgtt tgattcacgg gcaagtggca gttgtatgga ccaaagagtt aaatgcgccg
     6421 cttttagtag tggctaatga tgaagctgca aaaaatgaaa tcacacaaat gacgcttaaa
     6481 atggctgtgc caaacggcat gaaactgctt attcgttcag ttgaagactc gattaagctc
     6541 tttaatgatc cacgcgccaa agacaagcgt atctttgtga ttgtcaattc tgttaaagat
     6601 gcttgtgcca ttgctaaaga agttccagac ttagaagctg ttaatgtggc taatgtgggg
     6661 cgctttgata agtcagaccc agcaagcaaa gtcaaagtga caccaagtct tttacttaac
     6721 ccagaagaaa tggcagccgc aaaggaatta gtcagtttac cagaacttga tgtctttaac
     6781 caagtcttac catcaaatac caaggtccat ttgagccaat tagtcaacta aagagaggta
     6841 aaaaagtatg ttagtaccag caacaatggc agctttagct gtattgattt gttttggggg
     6901 aaattattta accggtcaaa gcatgatgga aagaccccta gtagttggac tggtcacagg
     6961 tcttctttta ggagatatga aggtcggtat cttaatgggg gcctctctag aagctctttt
     7021 cctaggaaat gtgaatattg ggggtgttat tgcagctgag cctgtaacag cgactgccat
     7081 ggcaacaacc tttaccatta tttcacatat tgaccaaaaa gcagccatga ccctagctgt
     7141 tccaattgga atgttggcag cctttgtggt tatgtttttg aaaaacgtct tcatgaatat
     7201 ctttgctcca atggttgata aagctgcagc agctaaccat caaggtaaac tagtgatgct
     7261 ccactatggc acttggatta tctattactt aatcattgcc tctatttctt tcattggtat
     7321 cttagtaggt agtggacctg ttaatgcctt tgtggaacac attcctcaaa atctcatgaa
     7381 tggcttgagt gctgcgggag gccttcttcc agctgtcggt tttgccatgc tgatgaaatt
     7441 attgtggacc aacaaattag ctgtttttta cctattgggc tttgtcttaa cagcttattt
     7501 gaaattacca gcggttgcag ttgctgccct aggagcagtt atttgcgtca ttagttccca
     7561 acgtgatcta gaattagacg caattactag aggtgcaatt agtaaacaaa caacctttga
     7621 ctctaaagaa tcagaagagg aggacttctt cgcatgacat cacaagataa tttgactaaa
     7681 gaagaccgta aaatgcttcg ctcagtcttt tggcgctcat ggacgatgaa tgctagtcgt
     7741 actggggcaa cacaatacca cgcagtaggg gttatttaca ctttactacc agtcatcaat
     7801 cgtttttata agactgataa ggataaagca gaggcactgg tccgtcatac aacatggttc
     7861 aatgccacca tgcacatcaa taactttatc atgggtcttg tggcatcgat ggaaaagaaa
     7921 aacagtgaag atcctgattt tgatgctagt gctattacgg cggtaaaagc atctctaatg
     7981 ggacctatct ccggagttgg agattccttc ttctggggaa ttttaagggt tattgcggca
     8041 ggtatcggga tttccttggc aagtgcaggc tcagccatgg gagctgttgt cttcttactc
     8101 ttgtacaata ttcctgcttt tattattcac tactatagcc tttatggtgg ttattctgta
     8161 ggtgcaggat ttatcaaaaa actttacgaa tctggtggta taaaaatcgt cactaaaacc
     8221 tcaagtatgc ttgggttaat gatggtaggc tcaatgacgg cttcaaatgt aaaatttaaa
     8281 acgattctta cagttgctgc gaaaggtgcc aaagaagcag cttctattca agattacctt
     8341 gaccaattgt ttattggtat tgtaccatta atggtaacac tagcagcttt ttggcttcta
     8401 cgaaagaaag tgaatatcaa ctggattatg tttggtatca tgttccttgg cattatcctt
     8461 ggacttttag gtatttgcta ataatctcct agcaataaag gtaagtaaga caagttttct
     8521 tgttttgctt acctttttcc ttttaagatg atgagacttg ttttgatgaa aaacgtagta
     8581 gcattaagaa atttgttata atgaaaggag cttaagatgc gaggtgaaca ggtggaagaa
     8641 cattttaaaa aacaattaca agatgatatt tctagacatt tttcgtacca atcgttaatg
     8701 ttatcattgt tgctaattgg tctttttatt attttttcat tagcgccaca acaattaggc
     8761 ctctatcgtg atatcaatgc cactgcaacc cgttatcacc gtttgattag caaacaagaa
     8821 gccttgctgg atgacttagg gaaaaatagc ttactacctt ttttaaataa aaacctcagc
     8881 actgctgatt taagcaagca ctattttcat ttgcgccata gcagccaaac gtcaccagaa
     8941 cttttactat tttcacctag tcaagacctt ttatttgcta gtaacccaca tttaggaaat
     9001 gtttttagta aatctgttta tattcaagaa gtcttgagag caactcatcc tccaaaaacc
     9061 ttgtttaaag ttgctatgga tagtgaagat ggtcactact tgatgatcat taagccaatg
     9121 atagatcaaa accaactaaa gggatatgct tttttagtga tgagtggcaa agattttctt
     9181 catcctacaa aaacattgac gtcagagttg gtcattgctg ataagctgga caatacgttt
     9241 acgttttcca atcgtgagtt tatagcatct agtctagata agatcaatag ccagtattta
     9301 caccattatt ttgtttttca agataatcga gcctttatca caagaaaggt tgccttacaa
     9361 ggaggtcttt ggctttacat gtataggccc ttgattccaa tggtatcggt gatgttattt
     9421 tcacttattt catcagctgt tatctttgtg attttgcaac gtaaatcaag tggtttagct
     9481 aaccgaattg cagctaaaaa ttcaagagca atcaatcaaa tggttagaga tatgagtgcg
     9541 atctctcggc aagaaaaaag acgtattgac cttgagagtc aagatgaatt tcaatattta
     9601 tctgatcaaa tcaatcaaat ggtagagcga ttgcaacagt tacatgataa aacgttagat
     9661 ttggaaactc aaaaattatt atttgaaaaa cggatgttag aagctcaatt caatccgcat
     9721 ttcctctaca atacgctaga aaccattttg attacgagcc attatgattc tgccctaaca
     9781 gaaaaaattg ttatccaatt gacaaaattg ttgcggtata gtctcacgga ttctagcaaa
     9841 cctgtcttgc tcaaagatga tttaagtgtc atcgagtctt atttagtgat taatcaggtg
     9901 cggtttgaag aattgcaata tagcattaac ctatccccag accttgatag tcttgaagtg
     9961 cctaaattgt tcttgttacc tttgatagaa aatgccatca aatatggctt gaaagaacga
    10021 cacgatgtca agattaacat tgcttgttat tatcaagatg accacattat tttttctgtg
    10081 agagataatg gttcgggaat tgatgctcat caccaaaaag tgattcgaga gcaattggaa
    10141 gctggagagt cacaccatgg gttaattaac tcttatcgtc ggcttaagta tcatttttca
    10201 gaagtatcct tggtttttga tcaaggtgat aaacagttta atgttagtta ccatgttaag
    10261 gagtagtcta tgtacaaatt agtcattatt gaagatgaac atattattag gaaatggttg
    10321 cgatacgcta ttgattataa agctttagat attttggtca ttggcgaggc taaagatggc
    10381 aaagaaggag ctgttttaat caaagagagt caaccagata tcgttttaac cgatattaac
    10441 atgcccatca tgacagcttt tgacatgttt gaagtaacaa aagatcaaac ttacgccaaa
    10501 attattttat ctggctatgc tgattttcca aatgcaaggt ctgccataca ctacggtgta
    10561 cttgaatttt taacaaaacc gattgaaaaa gcagctcttt gggaatgtct tcaaaccatt
    10621 attgctaaaa tagaaaagca aaaggggtct aatcaaaaaa cagatgcttg cgtctatatt
    10681 cccttacccc agatgactga tcagattcct gaagtagtca aagatatttt ggagtgggta
    10741 catgctcatt ttcaagacaa gatcagcacg agccgcctag ctcatgactt agggtatagt
    10801 gagagttata tctatcaaaa tatcaaaaag catcttcaga tgcctttaag tgattacatt
    10861 aatcaatatc ggattaatca ggcaattcaa ttgatgcaac aagaaccaga tttaatggta
    10921 tatgaaatag cacaagctgt aggtatttat gactatcgct attttgatag ggtttttaaa
    10981 aagtatctag gacaaactgt aaaggctttt aaagaagagc attttatgaa agataccgat
    11041 aggagtaagc catgttaaaa ctcaaacgca aatggctatt aagctttttg ttagtaataa
    11101 ttattctagc aatcgttaac gttgcaatgt atatattctc atcgtcaaaa aaagatagtg
    11161 ctaaagaatt agttatcttg actcctaata gccaaactat tttaacaggg actattccag
    11221 cctttgagga aaagtatggg gttaaagtaa gattaatcca aggtgggacg ggccaactta
    11281 ttgatcaatt aggtcgaaaa gataaaccat taaacgctga tattttcttt ggtggcaatt
    11341 acactcaatt tgaaagccat aaagatttat ttgaatctta tgtttctccg caggtttcta
    11401 ctgtcatttc agattaccaa ttgcctagtc atcgcgcaac cccatatacg atcaatggca
    11461 gtgtactgat tgttaataac gaattagcaa gaggacttca tattaccagt tatgaggatt
    11521 tgctacaacc agctttaaaa ggcaaaattg cttttgctga tcccaacagt tcatcaagtg
    11581 ccttctcaca gctgactaat atattgttag ctaagggggg gtacacaaac gctgacgctt
    11641 gggcttacat gaagcgcttg ttggtcaata tgaattctat tagggctacg agttcttcag
    11701 aagtctatca atctgtcgct gagggtaaga tgattgttgg gctaacctac gaagatcctt
    11761 gtatcaacct gcaaaaaagt ggtgccaatg tttccattgt ttatccaaaa gaaggaacgg
    11821 tgtttgtgcc ctcctctgtt gctattatca aacatgcgcc aaacatgaca gaggctaagc
    11881 tctttattaa ttttatgtta tcacgtgatg tgcaaaatgc ctttggccaa tcaaccagta
    11941 accgacccat tcgtcaagat gcccaaacca gtcacgacat gaaagcctta gaaacgatag
    12001 ctactttgaa agaggattat gcttatgtta ccaagcacaa gaaaaaaata gtggctacgt
    12061 acaaccagtt gcgccaacgg ttggaaaaag ctaagtagga gttaaaagta tggtattgtc
    12121 aacttgaaaa aggtcctaag gccttttttc tatgttataa ttaagaatca tcttcagttg
    12181 agaaagtaag gattatgcca ccaaaaacta ttgatattga aaagtaccac cagcttgctt
    12241 ggcaaaggca ggctgaacac cgaaagtttt tagcgacttt aaagaaaaaa ccacctaaac
    12301 atctagacaa aattgtccag gacattcatc aggaggtttt tcaagagatt gattgcacgt
    12361 cctgtgctaa ttgttgcaaa gaccttggac ctgatttgac agagaccgat attgtcaaaa
    12421 tcgctaaact attccgaatg aaattagcga cttttgaaaa gacttacttg cgcgtggatg
    12481 aggatgatga taaggttttc cggttcatgc cctgtccttt tttaggaggg gataaccttt
    12541 gaagcactta tgatgtaagg cctaaagctt gccgagaatt ccctcacaca gaccgtaaaa
    12601 aaatctacca gattaatcac ctcacttcaa gaacaccttg atttgtccag ccacctacga
    12661 gtttgtggag cggttaagca aacgtttgac ccgttcttag gctagaaaaa ggtgttcttg
    12721 tagtagaaag tgtatttatt atcacttttg acaaaaaatc tctttcccta attgttctaa
    12781 agaggcgaca atccttaatc actgttaaca aacagttaac cgataagtgg attaaggttt
    12841 gtcatctcaa ataaaatacc ctcaaaagga gaccttatga ccacagaatt tgacaaaatg
    12901 actagaggcg aatggtatga tgctaatttt gattcggaac tgattcaaaa acgcatgatg
    12961 gcacaagacc tctgtttcga tttaaaccaa ttaaagccta gtcgagaaga agaacgctct
    13021 gccgttttaa accaactttt tggacaatct tttgagggct tggtcctgct cagccctttc
    13081 atctgtgact atggtaagaa cattactttt gggaagaatt gctttattaa cagcaattgt
    13141 tatttcatgg atggggcgaa gattgccttg ggcgataatg tctttgtagg tccttcgaca
    13201 ggtttttaca cggcaaatca ccctctagat tataaacgcc gcaatgaggg gcttgaaaaa
    13261 gctttaccaa ttaccatagg agataatgtc tggtttggtg ccaatgtcaa tgttatgccc
    13321 ggcgttacta ttggcagtgg ttgtgtgatt gcgtcaggat cagttgttac ccatgatatt
    13381 ccagtcaatt cccttgcggc aggtgttcct tgccaagttg tacggaaaat tgagcaggag
    13441 tagaaagtga ggcaaaaagt gcattacaac tttctttttt tcgaccttga ccatacccta
    13501 cttgattttg atgcggcaga agaggttgct ttgaccaagt tgctagaaga gtaccaggtt
    13561 attgatatta aggcttacaa ggactactat aagccgatga atcagaactt atggaaacag
    13621 ttagaaggtg gggatattag taaagctgat ttggttaact ctcgctttgc tctgctattt
    13681 gctcattttg gagtgacggt tgatggcagg cagttagcag aaggttatca aaagcattta
    13741 aaagatcaag ggcaagttta tgctggtgct aaggagctgt tagcggactt aactgcccaa
    13801 ggctataatc tttatgcggc aactaatggc atcgcaacga ttcaacaagg ccgattgcaa
    13861 gcgtctggtt tggcacctta cttcaaagcc attttcattt cggaacagtc gggtagtcaa
    13921 aaacctaaaa aagctttcta tgattggatg acccagcagg tttccaatta ccaacctgat
    13981 caagctttga tgattggtga tagtttatcg gctgatgttc aaggtggaat taatgctggc
    14041 atggatacct tatggtacaa cccaaagcat ctcctgaata acagccctgt tcatcctacc
    14101 tatgaggtgt cagattatca agctctgctg aattgtattg cggagtaaca gacaatagcc
    14161 tttaaaaata gcgtagtcat tttttgaaat cgatttcata atctggtaga ctaaggttat
    14221 cacgaaaagg aggctatatg tgatggctta tcaaactatt tacccttata caaatgaagt
    14281 ccttcataca tttgataata tgaccgatca aggtttggca gatgtccttg aaagagctca
    14341 ccttctctat aaaaaatggc gcaaggaaga tcatttagaa gaacgtaaag cccagcttca
    14401 tcaagtggct aatattcttc gtcgtgaccg cgataaatac gctgaaatca tgaccaaaga
    14461 catgggaaaa ctgttcacag aagcccaagg tgaagtaaat ctttgtgccg atattgctga
    14521 ttactacgct gataaggcag atgaattttt gatgtctacg ccactagaaa cggattcagg
    14581 tcaagcttac tatttgaaac aatcaactgg tgttatccta gctgttgagc cttggaattt
    14641 tccttactat caaatcatgc gggtctttgc gccaaacttt attgttggaa acccaatggt
    14701 tttaaaacac gcgtccattt gcccacgctc tgcccaatct ttcgaagaat tagttcttga
    14761 agctggtgct gaagcaggta gtattaccaa tttgtttatt tcttatgacc aagtatcaca
    14821 agtgattgct gataaacgtg tggttggtgt ctgcttgaca ggttccgaac gtggaggagc
    14881 tagcattgca gaagaagctg gtaaaaactt gaaaaaaaca acccttgaat tgggtggaga
    14941 tgatgccttt attatccttg atgacgcgga ttgggatcaa ttagagaagg tgctttactt
    15001 ctctcgtctc tacaatgcag gtcaagtatg tacctcatcg aaacgtttta tcgtgcttga
    15061 caaagactat gaccgtttca aagagttatt aacaaaagtc ttcaaaacag ctaaatgggg
    15121 tgacccaatg gatcccgaaa cgacgttggc gccattatca tcagctcaag ctaaagcaga
    15181 tgttcttgac caaattaagt tggccttgga tcatggtgcg gagttggttt atggtggtga
    15241 agcgattgat catccaggtc attttgtcat gccaaccatt attgctggcc tcacaaaaga
    15301 caaccctatt tactatcaag aaatctttgg cccagtcggt gaaatctaca aagtgtcttc
    15361 tgaagaagaa gcgattgaag tggcgaatga ttctaactat ggccttggag gtactatctt
    15421 tagtagcaat caagaacatg cgaaagccgt agctgctaaa attgaaactg gtatgtcttt
    15481 tatcaactca ggctggacaa gtcttccgga actcccattt ggtgggatta aacattcagg
    15541 ctatggtcgt gaattgagtg agcttggctt tacatctttt gtgaatgaac accttatcta
    15601 tattccgaat aaaacgaata atggcaatac taaagtttga tctagattgt taaaggagat
    15661 ctgctcgcct taataaacaa tcaaggcgtt acactcttct tttttaaagt caaaatttta
    15721 aaaatttgat aaactagtaa catgaacgaa ctgattaaac ataaactaga actcttacca
    15781 gacagccctg gctgttactt acataaagat aaagaaggaa ctattatcta tgtcggtaag
    15841 gccaagaatt tgaaaaaacg cgtccggtcc tattttcgtg ggagccatga taccaaaaca
    15901 gagttactag tatctgagat tgtagatttc gaatatattg taacagagtc agataccgaa
    15961 gcgcttttgt tggaaattaa cttgattcaa aaaaatatgc ctaagtacaa catcaagtta
    16021 aaagatgata aatcttatcc ctttctcaaa atcacaaatg agtcttttcc tcggttagtg
    16081 attacaagat atattaagaa aaatgatgga ttgtactttg ggccctaccc agattcttac
    16141 actgctaatg aagttaaaaa gttattagat aggatttttc catttaaaaa gtgtaaaaat
    16201 cctatcaata aggtctgttt ttattaccat ttaggccagt gctgtgctca taccatttgt
    16261 catacagaca aggcctattg ggatcgttta attgatgatg ttaagcactt tttaaatggt
    16321 aaagatgaca aaattattga agatcttcgt tctaagatgt tagcagcttc taaagaaatg
    16381 gcatttgaac gtgccgctga atatcgagat ttgatttcag gtattgccac catgcgcacc
    16441 aagcagcggg tgatgagcaa ggatttgcaa gatagagata tctttggcta ttatgttgat
    16501 aagggatgga tgtgtgtcca agttttcttt gtgcgtcaag ggaaattaat tcagcgtgat
    16561 gttaaccttt ttccctatta taccgatgca gaagaagatt tcttaactta tatggggcaa
    16621 ttttaccaag ataaacagca tttcatccct aaagaagtct ttattccaga agctattgat
    16681 gaagaactgg tagccgctat tgtgccaacc aaaatcatca aacccaaacg cggtgaaaaa
    16741 aaacaactgg tagctttggc tactaagaat gctcgtgtta gtctgcaaca aaaatttgat
    16801 ttattagaaa aagatatcaa aaaaacgagt ggtgctatcg aaaatttagg tcagttactt
    16861 aggattgaca agcctgtgcg cattgaagcc tttgataatt ctaacattca agggacaagt
    16921 ccagttgcgg ctatggttgt ttttgttgat ggcaaaccta gtaagaaaga ttatcgtaaa
    16981 tttaagatta aaacagtggt gggaccagat gattatgcca gtatgagaga agtgcttttt
    17041 cgaaggtaca gtcgggtgaa aaaggaggga ctgcaagctc ctaacttgat tattgttgat
    17101 ggaggcgttg gacaagtcaa tgtggccaaa gatgtgatag aaaaacaact tggactcact
    17161 attcctgttg cgggacttca aaaaaacgat aagcaccaga cccatgattt gctttttgga
    17221 aacccacttg aagttgtacc gttgccgcgc cgttctgaag agtttttctt actgcatcgg
    17281 attcaagacg aagtgcatcg ctttgcagtt acatttcata gacaagtgcg acgtaaaaat
    17341 tctttttcat caacattaga tcatatttca gggcttggcc caaagcgaaa acagttatta
    17401 ctaagacact ttaaaaccat aacagcgatt gcatcagcta cctctgagga gattcaagct
    17461 ttaggtatac ctaaaacagt agttgaagca atacagcaac agataacaga caataaaaat
    17521 gatagatcgt ccccttaaat aagtgttatg ttttcagtac tgatgaggta aaaaggcgct
    17581 acttgttacg cacgacattt cagttcgtta ttttgaaact ttcagaaggt tgcgaagtgt
    17641 agtgagttta tgattttaaa aactatttta tggtaaaata aaatggtatt aaaaaaaaca
    17701 gatttagata ggaagttttg aaatgaaatt tctagagtta aacaaaaaac gccatgccat
    17761 taagaccttt aatgaccagc cagttgacta cgaggatttg cgaacagcca ttgagattgc
    17821 aaccttagca cctagtgcca ataacattca accttggaaa tttgtagtcg ttcaagagaa
    17881 aaaagctgag ttagcaaaag ggttacctct agcaaataaa gtgcaggttg aacaggctca
    17941 atatgtagtg gcgctatttt cagacactga tttagcttta cgttctcgta aaattgcccg
    18001 tatcggtgtc aaatcattac cagacgactt aattggttat tatatggaga ctttgccacc
    18061 acgttttgct gcttttaatg aggttcaaac cggtgagtac ttagctatta atgcaggcat
    18121 tgtggctatg aacttggtgt tatccttgac ggatcaaaag attgcttcca atattatcct
    18181 tggttttgat aagtcaacga ccaatgagat tttagacatc gatccgcgtt ttcgtccaga
    18241 attattgatt actgttggct atagtgacga gaaaccagaa ccaagttatc gtttgcctgt
    18301 tgatgaagtc atcgaaagaa gatagagtca ggacaattag ttaaatgtaa tgtccagatg
    18361 cgctactgag cgaccactat tgttagactg atactatttt ggcttatttt aagttaaaca
    18421 ttatccctaa aacgaataag gagagtataa tgacaaccat tgattttaaa gcagaagttg
    18481 acaaacgtaa aaaagctatg ctagcagatt tagttgacct attacgcatt aattcagaac
    18541 gcgatgacca attagctgat gataaacacc catttggccc aggtccagtt aaggccttgg
    18601 agcatttcct cgcaatggct gagcgtgatg gctacaaaac gcgtaatatt gataactatg
    18661 caggtgactt tgaatttggt caaggtgatg aagtactagg aatctttggt caccttgatg
    18721 ttgtgccagc tggtagcggt tgggatacag acccttatga gccagtgatt aaagacgatc
    18781 gcatctatgc gcgtgggtct tcggatgata aaggaccaac catggcgtgt tactacgctc
    18841 tgaaaatcat taaagaactg ggtcttcctg tgtctaaaaa agttcgtttc attgttggta
    18901 ccgatgaaga atctggctgg ggggatatgg attattactt tgctcataat ggcttgaaaa
    18961 atccagattt tggtttctca ccagatgctg aatttccaat tatcaatggt gagaaaggaa
    19021 atatcactga atacctccat ttcgctggtg acaacaaggg cgcttttgtg cttcatcgct
    19081 tccaaggtgg gttgcgtgaa aacatggtac cagaatctgc cacagctgtc attacggcac
    19141 cgcatgacct tgatgtgcta gaagcagctt tggagcaatt tttatcagaa catggtgtta
    19201 aaggttctat gaaggctact gatggtaaaa ttgaagtaac tattattggt aagtctgctc
    19261 acgggtcgac tccagaagcg ggtgttaatg gtgctacctt gttggctaaa ttcctgaatc
    19321 aatttacctt tgaaggggct gctaaggatt atttacatgt ggcaggtgag gtgcttcatg
    19381 aagactttgc ggcagaaaaa ctaggccttg cttatactga tgaccgtatg ggagccctga
    19441 gcatgaacgc aggtgtcttc acctttgata gtcaatcagc tgacaatacc atcgccttga
    19501 atttccgcta tcccaaagga actgatgcgg caaccttaaa agcaggattg gaaaaattac
    19561 caggattaac taaggtaagc ctttctgagc atgaacatac acctcattat gtgccaatgg
    19621 atgatgaatt agtagctacc ttacttgctg tttacgaaaa acaaacaggt cttaaaggct
    19681 acgaacaagt tatcggcgga ggaacctttg ggcgcttgct agaacgtggt gtggcctttg
    19741 gagcgatgtt cccaggtgat gaaaacacta tgcaccaagc taatgagtat atgcctttag
    19801 aaaatattta tcgctcagca gctatttatg ctgaagcaat ctacgaatta attaaataag
    19861 atgcttatga cagcaaaaag agctggaaca ctgttccagc tcttttgtga tgattagaga
    19921 ctgttgttat ttaccaagac agaattgact aaagagttgg gtaatgagtt catcaggagc
    19981 agcatcccct gtgatttctc cgagaatttc ccaagttctg gttaaatcaa cctgtagtaa
    20041 atcaactggc atgccaagcg ccaaaccgtc attgacagct tctaaactct ggactgcctt
    20101 ttcaatcaaa gaaatgtggc gggcatttga caggtaagtg gcatcttgct ctaccaaacc
    20161 agcgttgtca aagaaaagct ggttgatacg atcttcgatt agattaatgt tctggttggt
    20221 taaaacggaa atgggaatgt agtcatctgg taattgctct aattcaatct tctgttccaa
    20281 atccgtttta ttcaacaata taatacggtt actgtcctga ctgagattta acaaagcccg
    20341 gtcttggtca gtcagttttt cagaagcatt cagcacaaga agaacaaggt cagcttcttg
    20401 aagagctttt ttagaccgtt caactccgat ttgttcgacc agatcatctg tctcacgaat
    20461 accggccgta tcgacaagtt ttagaggaac tcccttgata ttaacgtatt cttcaatgac
    20521 atctcgggtg gttcctgcaa tatcagtcac aatagccttg tcttctcgca acaaattatt
    20581 aagtaagctt gacttaccga cgtttggacg accaataata gctgttgata agccctcacg
    20641 cagaatttta ccgcgtttag ctgttcgaag gagactttcc aaaaggcttt ggaattcttg
    20701 tgttttctca cgtagcagag cagtggtcat ttcttccaca tcgtcgtatt cagggtagtc
    20761 aatattgact tcgacttgag ctaaggtgtt gagaatttcc tgacgggtgt cattgataag
    20821 ctgggaaagg gagccatcca gttgcttgac tgcaatcgtc atagccttgt ctgttttggc
    20881 acgaataatg tccatgacag cctcagcttg agtcaaatca actcgcccat ttaagaaggc
    20941 acgtttggtg aattcgccag gctctgccat tctagcgcct tggcgaatca atagttgcaa
    21001 gatttcattt gtcacagcaa taccaccgtg cgtattgatt tcaaccacat tttcacgggt
    21061 aaaggttttg ggggctagca tgactgacac cataacttca tcgataatag ttcctgtctt
    21121 aggattaatg atatggccat agttaatggt gtgtgaggcg acttgctcta agttctttcc
    21181 cttaaaaaca gattgtgcaa tggcaagcgc atctgtccct gataaacgaa caatgccaat
    21241 agctccttca ccaagagggg ttgaaatggc ggtaattgta tcaaattctt tagttatact
    21301 catgccctct attttaaatc aagtcctagt agaaagcaag gtgttatttg tatagaaaat
    21361 aggactagca ccattttgag tttag
//
LOCUS       DAUGJR010000033        21083 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUGJR010000033 DAUGJR010000000
VERSION     DAUGJR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21083
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.033"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(124..423)
                     /locus_tag="VH800_001282"
     CDS             complement(124..423)
                     /locus_tag="VH800_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362350.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(580..1047)
                     /gene="perR"
                     /locus_tag="VH800_001283"
     CDS             complement(580..1047)
                     /gene="perR"
                     /locus_tag="VH800_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEQ8362351.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(1099..1554)
                     /locus_tag="VH800_001284"
     CDS             complement(1099..1554)
                     /locus_tag="VH800_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEQ8362352.1"
                     /translation="MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNL"
     gene            complement(1741..4383)
                     /gene="polA"
                     /locus_tag="VH800_001285"
     CDS             complement(1741..4383)
                     /gene="polA"
                     /locus_tag="VH800_001285"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEQ8362353.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(4514..6241)
                     /locus_tag="VH800_001286"
     CDS             complement(4514..6241)
                     /locus_tag="VH800_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEQ8362354.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMTMASGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAKKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(6257..7453)
                     /locus_tag="VH800_001287"
     CDS             complement(6257..7453)
                     /locus_tag="VH800_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8362355.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(7941..9032)
                     /gene="ulaG"
                     /locus_tag="VH800_001288"
     CDS             complement(7941..9032)
                     /gene="ulaG"
                     /locus_tag="VH800_001288"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEQ8362356.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(9285..10931)
                     /locus_tag="VH800_001289"
     CDS             complement(9285..10931)
                     /locus_tag="VH800_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEQ8362357.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(11256..11960)
                     /locus_tag="VH800_001290"
     CDS             complement(11256..11960)
                     /locus_tag="VH800_001290"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEQ8362358.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVARMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(11962..12825)
                     /locus_tag="VH800_001291"
     CDS             complement(11962..12825)
                     /locus_tag="VH800_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEQ8362359.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPAIEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(12830..13492)
                     /locus_tag="VH800_001292"
     CDS             complement(12830..13492)
                     /locus_tag="VH800_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEQ8362360.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     MKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(13583..14068)
                     /locus_tag="VH800_001293"
     CDS             complement(13583..14068)
                     /locus_tag="VH800_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8362361.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALVTLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            complement(14191..14469)
                     /locus_tag="VH800_001294"
     CDS             complement(14191..14469)
                     /locus_tag="VH800_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8362362.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(14540..15973)
                     /locus_tag="VH800_001295"
     CDS             complement(14540..15973)
                     /locus_tag="VH800_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8362363.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(16280..18781)
                     /locus_tag="VH800_001296"
     CDS             complement(16280..18781)
                     /locus_tag="VH800_001296"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEQ8362364.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASA
                     IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(18992..20131)
                     /locus_tag="VH800_001297"
     CDS             complement(18992..20131)
                     /locus_tag="VH800_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEQ8362365.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELAQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMSFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
BASE COUNT         6225 a         4645 c         4035 g         6178 t
ORIGIN      
        1 taaaccttgc ttttcttttt caaggtaata gactctactc cttgtaagtc taacttattc
       61 ttaatcttat ttatcgctca ttttttaaat tccgatgctc tcacagatat tatcattgtt
      121 tagttacatg tctgtcaatc tattcgccac cacactaggg gccatctgat tgaaaaataa
      181 aatttcggag tccattgttt gctcaagaat catatctgtc acaattacgt catactctga
      241 agacagtgac accatatcaa ccatggtcag cctcaagtca tcaaagttga taatctcaaa
      301 aaatcctcca aaatactctt ttaagaagtt gccaacattg ttataacttc tctcaaccac
      361 taatagtttc aagcgacgac gcgattgatt tgtaagaaag agattttccc aggtgaggaa
      421 caaacaaata gaggagatga ttgatggttc tttcctttaa ttccttatga tccccagcaa
      481 ataactcttt aacataagca acaaaggtct ggtattgaac tgggggtttt tgatttgtaa
      541 aggcactata tttataatgc ctttatttaa gggttaactc taaaaatcag attggtcttt
      601 tgcttggcaa tccggacaaa tcccgtaagc aataactggg atacgcgtga ccttataacc
      661 tgtttgctca tgggcttctt tggcaatatc cataacatca acatccataa agtcagcaat
      721 cttcccacat atttcacaaa ctacattgac gtgttgatgg cccataaagt catagtaggt
      781 ggttaaatca ttgctgattt tcaactctga gacaaaacct tcatcaacta aaactttcaa
      841 attattatag actgtggcaa ggctcatgtt aggaaagtta ggctgtaagt cacggtaaat
      901 cttatcggca ctagggtgtt ctgtggactg aatcatgtaa gaaataatgg ctttacgtgt
      961 ctctgtaatt cgaatatgtt tttcccgtag atgctctagg acattttcat aggcatctag
     1021 ggcttgctga tgtgaatgaa tgtccataag ctgctactcc tatccttttt tcctttatta
     1081 tcacgcacgt ctctagtttc aaagatttgt gatgcattct ggtttagcga ctaattgcaa
     1141 atagtctatt tttaggcagc gattcatcac aatagcctct ttgcctgccg accgtaaaat
     1201 ggtttgtact tcttggtttt caaggcctaa ttgcgcccaa aagactttgg cctgacctgc
     1261 taaaaagtct ctggcaactt ctggtaaaaa ctcacttctg cgaaagacat ctacaatgtc
     1321 aacctcaaag ggaattgcct tgatactggc atagaccttc tctcccaaaa taagctgacc
     1381 tgctaatttg ggattgactg gaatgatccg ataatccata gcctgcataa atttggcgac
     1441 accataagct gctgtgtctt tgcggtcaga aagaccaaca accgcaatgg ttttggctga
     1501 ctccaagtaa gcttttagga tatcctctga gggattttga aacgaataaa tcacttgttc
     1561 ccctatctat ttaataacct ctacagctgt tcaatatagc aggataactc ctaaagcatg
     1621 gcttcaatca cttttaacct tatccgtcaa aaagctcaaa gcagcttcat gacttctcct
     1681 acaatttttt agtttattat aacataagtt gtcaaaatga gaaataacaa gtaagaaaac
     1741 ttatttggct tcgtaccagc tctgcccagt actttcatcg acacataaag gaacagctaa
     1801 atcaacagca gcttccatgg tgtctttgac aagttttttt atagcagtca actcatcatt
     1861 tggcacttcc aaaacgattt catcatgcac ttgaagcagc attttagctc taaaaccacc
     1921 tgcttgcaag gccttatcca gattaatcat agcgattttg agaatatcag ctgcgcttcc
     1981 ttgaatgggc gagttgatgg ctgtacgctc cgcaaaagag cgaacgttga aattacgaga
     2041 gttgatatcc ggtaattcac ggcgacgctt aaagagggtc tctacatagc ccttgtcttt
     2101 agcctcacgc accacatttt ccatataggc tttaatccca ggatagcgtt caaaataggt
     2161 atcaatgtaa gacttggact gtttacgggt gataccaagg ttatttgaca aaccaaaatc
     2221 agaaatccca tacacaattc caaagttaac agccttggca ttacggcggt cattggcagt
     2281 aacatctgct gccttgtcaa tcccaaacac acgcatagcc gttgaggtat gaatgtctgc
     2341 cccttcatta aaggcagcaa tcaaatgctc atcccctgaa atatgtgcta gcacgcgcaa
     2401 ttcaatctgt gagtaatctg aactcaacaa gacggcatct tcatgagatg gggtaaaggc
     2461 cttacgaatc aaacgcccct gttccaaacg aatgggaatg ttttgaagat tagggtccac
     2521 actagacaaa cgccctgtct gggtgagatc ctgcacatag cgggtatgaa tcttgccatc
     2581 agccagaata taatcctgta aaccaatcac ataggtggat tgcaatttag taatctggcg
     2641 gtaatccaaa attttagcca caattggagc aatcggtgcc aaacgttcca aaacatcaac
     2701 agctgtagaa taacctgttt tggtcttctt agtcatctca agaggtagtt gcatcttctc
     2761 aaacaagata ctgcccagct gtttaggcga attaatgtta aattcttggc cagccatatc
     2821 ataaatctct tgggtgagcg cttcaataat gaccttgttt tgctctgcca tatcttgcaa
     2881 agtcgcccta ttaaccttga tcccttcaat ttccatttta gcaaggacat tagccaaagg
     2941 caattcaata ttctgataga ggtctagttg ctcatgggca gtgagcttgt ctagcatttg
     3001 agacttgcta tctaataata ctttgacctt acgagctaag tgttctagta agacgtcttt
     3061 atcaggaaca gcccgtttag cacctttacc atagaccgta tcgtcttctt ccaaagagat
     3121 gtcagtaaaa atgcgggcaa tggtgctaag ctcattgtct tctacagttg acagaaggta
     3181 attagctagt ctagcatcat agctaggtgc taccaactca attcctaagt ggctcaacaa
     3241 gaccttgcta cgtttaaaat cataagtggc aatgggtttt tggaagacct gcttaaaact
     3301 atccgtcgct aataggctaa ggtctgtgga tgcgtaaatc tgctcaccat gtccccaagc
     3361 aaaaccaatg atggcctcac gatggtaatt atcccgaagc gtttcaaagt agaagatgtc
     3421 ttctgcgcta aacaaatcag cagacacatt ggtcacttct tgataggaaa tgacagctac
     3481 tggctcttga ggcatctggc tagcaagacc tttcttgagt tgcacaaaat ccatctcatc
     3541 gtaaaattga gagaggctag caacatctgg accattgtag acaatatcat ctaagccaat
     3601 tgtgatagga gatgctgtat tgatagtggc gagcgtttta gataggaaag cttggtcacg
     3661 gtcattgatc aagttttctt tcatttttga ggtcttgaat ccatcaatat gctcgtaaat
     3721 gccttccaaa ctaccaaatt catgaaggag cttaaggcct gttttttctc caatttttgt
     3781 cactccagga atgttatccg atttatctcc catcaaggct ttgaggtcaa taaactggtt
     3841 tggcgtcaag cccatttttt ccatgaggta agccggtgtg aattcttcaa attcggcaac
     3901 ccctttttta gaaatttcaa ccacggtatt ttcgtcagtt aactggatca aatctttatc
     3961 accactgaca atggtcacat caaaaggcac ttctgtgcgc tccgccattt tatcaagcgt
     4021 cccgataata tcgtctgctt cgtagtgttc caactcataa taagcaatcc caagggctgt
     4081 caacatctca cgaatataag aaaactgctc acgaaattca tctggggttt tagcgcgacc
     4141 cgccttataa tcggcataca tttctgttcg gaaggtggtt ttgcccgcat caaaagccac
     4201 cagcacgtga gtaggccgga ctcttttcat catgtggtct agcatcaaat gaaagccata
     4261 aatggcattg gtatggagac cgctatgatt tttaaagcgg tcaatttgat tgtaaagggc
     4321 aaaaaaggca cgaaaggcaa cagaggagcc atcaattaat agtaatttat tcttgttttc
     4381 catagcctta ttataacaca gagggacggg cttttctcct ttaagccatt ggttttgctg
     4441 ataagtaaat ggttaaccta aaaagcctag gaaaattcct agacttctgt atttgctatt
     4501 tagacaaaag cacttatttt gtccaacttg atactttaga tttgtttgcc tctacccatt
     4561 ttttggcggc agcttctgga ctcatgcctt tattgatgtc aagcatgact gcttccatat
     4621 ctttttgggt ccagtggaac ttatcaatga ttttgtagac atttggaaga tcttttttca
     4681 agcctttacg agcaatggta ttgatgttct cagtcgagcc aaaggtttct ttaggatctt
     4741 taaggtactt caagtcatac ttggcaaaca tccagtgtgg tgaccaagct gtcacgacaa
     4801 taggatcttt tttcttgatc gcttgatcca aggaagtcgt catggctcct gttgatgccg
     4861 ccactaactc ccaactagat agattatgat actcttttag agtctttttg gctgctgcca
     4921 tgatacctgc acctggttcg atccctgtga ttttttgatc ggcttgtttg cttaaatcct
     4981 caatactatt aacatctgtc atgtatttag gaacagctaa accaagtttg gtccctttta
     5041 ggttaggtcc taaatcatct aattttgact tgtatttctg atattgttgg ccatgggtga
     5101 ctggcaacca agcactagtt gaaaaatcag cgttcccatt tgcaacggtt tgccacatga
     5161 cagcattgtc aagcggtgtc aaggttacat ggtaaccttc gtttttcaaa acttctgcaa
     5221 tcacatgagt tgaggcaacc tcagaatccc actgcacgta agcgatgtta acagtttcac
     5281 ccttatctgc cataccagaa gccatagtca taataccgcg tcctaaagca gctatcaaaa
     5341 agacagcaag ggctgctaga ccaatccatt tattggtttt gccagctttg gctttttctt
     5401 gaggtttgct attgaacaac tgtgtcatac ggtcaagaac aatcgccaag ataaccaagg
     5461 caagaccact gacaaatcca ctaccaatat cagcgtgttg aagggctgac aagacttcac
     5521 gtcctaaacc aggagcacca atcatggagc ctgttactac catggaaagg gctaacatca
     5581 tggtctgatt aacacctgcc ataatagtat ttttagctaa aggcaattca actttaaaga
     5641 gcttttgttt cccagttgac ccaaaggcat ctgaggcctc aatcaattct gttggaatgt
     5701 cacgaatggc caaatttgta aaacgaactg ttgggggcaa ggcaaagatg actgaagcaa
     5761 atactccagg caccatacca ataccaaaaa aggcaacggc aggaatcaag taaacaaaag
     5821 ccggcatggt ttgcataaag tccaaaatag gattcacaat ctgacggaca gtggcatttt
     5881 tagccatcca aatccccagc ggaataccaa taagtaccga aatcaaacta gctactaaca
     5941 ccagagtaaa ggtattcatt agctgcttcc ataacccttg attgtaaata aagagcaatc
     6001 ctaacaaggt aaaggttggc aaaggccatt ttttcttagc aaggaaaaac atccctgctg
     6061 ttactagaac aataaaaagt aacgggtgga taaataaaag tgttttggtc atccaatcca
     6121 tcaaaaagct accaactact tgcataatat caaatagacc tgagaaagtt ttagttagcc
     6181 actccgttag ctgctccacc agttgagcta ctggtaattt tgtttgtaat atcgtttcca
     6241 aaatgcatca ctccttttag ttaaggtctt cgtctgagat attagccaag gcttcaatca
     6301 ctcgtcctcg aataatgaca cctaacagac gattattatc atctgtcact gcaatcggag
     6361 cagatgaatc atagataaga ggcaaaatat ctgtaataat agtatctttt gagacagttc
     6421 tcacatcgcg atcaatcact tctgatagcg gtaacccttt tttgcgcgcc tctatagcgg
     6481 catcggccgt caaactgccg actaattggc ggcggcgatt cgtcgccatc aacatagaca
     6541 cctcttcgtt gtgcatacgg ttcaaggcaa cttgaggtcc atctaattca acagtagttg
     6601 ttaacggttt gatcatgata ttttgtgctg tcaagacttt agaacggtcc acatcctcaa
     6661 cgaattcacg cacaaagtca ttggctgggt tagtcaagat ttcctcacca gtaccaattt
     6721 gcataatttg tccgtctttc atcaaagcaa tccgatcacc aatccgcaag gcttcattca
     6781 agtcatgact gataaagatg atggtttgtt tcatgctgtc ttgcaaatca agtaattcat
     6841 cttgcatctc acgacgaatc aaaggatcaa gcgctgagaa tgcctcgtcc attaagagaa
     6901 ttttagggct attagctagc gcacgggcta ggccgacacg ctgctgcatc ccaccagata
     6961 gttggtttgg gtactggtct ttaaaatcta ataggcctga attatcaagg gctttttctg
     7021 ccaatcgctg gcgttcttct ttgggaacgc cacgtaattc caaaccaaat tcggtatttt
     7081 ccaaaatggt tttatgagga aagagggcaa agctttggaa aaccatgtta atgtcatggc
     7141 ggcgcacctc acgcagctga tctgctgaca tggttgagat gtctttacct tccagcaaga
     7201 tagatcctgc tgaaggttca atcaaacgat ttagcatgcg gacaagggtt gatttcccac
     7261 ttcctgatag ccccataata acaaagattt cacctttttt gacctcaaaa ctagcgtcat
     7321 agacacctac agtagcgcct gttttcttaa aaatctcact cttatttttg ccagtcttta
     7381 ccatctcaag agctgctttt tgttttttgc caaaaatttt actgagatgt ttgacttcta
     7441 aaattgtttc cattcgtttt ttctcctagg taatcgttta tcatgtgaaa taatgacata
     7501 gctttggcga aatattagcc aatatttaac aaagtagctc tacacaatta ataaacgtgt
     7561 ggtcactttt ttacttaaaa aaagaatctg ccgaaacaga acataactat attatcacgt
     7621 gtggtcactt tttgtcaagg acaataactc gatctggtaa tgccacaatg ataggtgatc
     7681 gctttcattc ttttaggtat ggtcttttaa ccagtacaat tttttatcac aactgatggc
     7741 tatttctttg ctgattaggc tattgttaca ttagaaatcc ttcttttacc tataatatct
     7801 cttttgcggc catcgtaaat aacgaccacg gtgactctta aacatttgct catctctcca
     7861 aaaaaactca cctaagacag tgtcctatga agcgagttag cttaatcagg cactatcatc
     7921 ttaggtgagt agggtgttgc ttatagtaaa gctttaaatt ggatattaga atcttctaag
     7981 aagcagtcat caaatccacg aggatgatgg tattcgatac gattttggtc ttgtggatag
     8041 gtgtacttgc caccaacctc ccagataaag ggatggaaat cgtattggag acgttctttg
     8101 cgcattttcc acagttcaag gatttcatct gttgatgcca taaagtttga ccaaatgtca
     8161 taatgaactg ggataacgac tttagcacgg agattttctg ccatacgaag aaggtcaaca
     8221 gaagtcatct tgtcttgaat tccaattggg ttttccccat agttatttaa cacaacgtca
     8281 atatcataat cacgtccatg tttagcaaag tagttcgaaa aatgagaatc cgcaccatga
     8341 tagatggtac cacctggtgt ttcaaaaata tagttaacag ctttgcgagc catgtcatca
     8401 tctgtgatag ctaaacctgc taaatcacca tcttgagcat cagctccttg tattgggaga
     8461 gttaccagac aggtgcggtc aaacgactct acagcggtga tcttaatatc tttgaattca
     8521 aagctatcac ctggctttaa gatcataata cgatcttttg gcacacccca atttttccaa
     8581 acttcaccac attcataagg tcctacaaat ttaacatgat taagttttgg gttattgata
     8641 atggctgccg cagtattgat atcgatgtgg tcactatgat aatgagaaac caaataataa
     8701 tccaactcat taatcataaa tggatcaatc accattggtt gggccctaag attgggctgt
     8761 aatttacgag ctcctgccat attagccatt tgatgtccac gaaccatatc cttaacttgc
     8821 ttggtcgctt tcccacgatt tgaccataag tccatgacaa cattagcacc gcctggtgtc
     8881 ttaatccaga taccacagtt tcctaaccac cacatcgcaa agttgtcagc tggcacgact
     8941 tcttgctcga tttcttcatt taaccatgtt ccccattctg gaaacgtgtt aaggatccat
     9001 gattcacgtg taatatcttg tactttagtc attagggttt cctccgaatt tgttcttcat
     9061 ttctatactt taagtataga ctttcttgtc aatgataaaa agaccaagtg tcacacagat
     9121 ctgtgttcaa aagtggactg actttttcat tagctcagtc taatactgtc tcattttgca
     9181 cactgtatct tgcatcaata ctgtattcaa agctatatta aaaacctcag ttatattttt
     9241 ctatgtcata gaaaactgag gtactttgac gacttaacac ttactcatag cagctcgcga
     9301 tgaatgagtt tttcaatttt agaaaccaag gcataacgat ctgattcatc ttttacaaca
     9361 gcttcaatag cttttgtgag ctctgtagaa aagcgggagt gctcactcaa gcgtccttgc
     9421 tttgaaaagc gtatcaattt gatgatatca tcgtcactta aaatagggtt aacaataagc
     9481 atcgggattt tagtctttag cgtatctgta gtagcaacaa tcatatcgac tgctaaaagg
     9541 tcgtaaacac tctgatactg ttctgtcgta aaaacagctt caatctgacc atttgctaga
     9601 tacctttgac actgtttgaa caataacttt tgaatgccta tcccatcatc tgaaacaata
     9661 acgagtttgg tcttttcttg ctctgtatta ttgtgacgca gctctccccc aagatggata
     9721 gtcaagtagg caatatcatc gtctgtcaag ctaatcgtcc aatcttgttc caaaatagtg
     9781 gcacaagatt gagtcatagc aaacaattct tcgtattttt ctttaatatg gtctgttaag
     9841 ggattaacta aaaaaatccc ataagcttta cggtaaacga gcgccttaca gtgggtcgtc
     9901 aactgcttca gcaaatcctg tttatgcgtg aaatgtaact gataacggct ctccaactgg
     9961 tcaataaagt gactaatggt tgctcgcatg tcgtcataat cttgactttc cacgtgatga
    10021 tcttgatctt ttcgaaaaga caacatcaac atcgctacca tactaacttc gatatcatcc
    10081 aaatgaagct taaaattatg gtaaagctct ctagctaaat cctgagcaat gtgatattct
    10141 ttacgtttcc aaatcaaatg aaattcttgt ttaagagcag actttgtttc tgaatcaaga
    10201 cgcatattac gataacttaa aagcatgaaa ggtaaaatct gcaacatgaa ttggctatct
    10261 tgggtattaa ttgtctttcc taaactagct tgagataaaa agagatactc atgaaaatag
    10321 gtcaaaatat ctttagaaaa ataaaccgat aagccttgta tctctgagag tttacggttg
    10381 aatatatcaa taaagctagt attgccacct tggtaaacgt ccactaacaa tttgtacagg
    10441 tattgaataa gagccattgg atgacaacca aaataatatc ccctagcctt tgtcgcatga
    10501 agctgaatct tgtattgttt gtcttccagt tcttccctta actcagtcag gtcatttaaa
    10561 atcgtgttac gagacacatc attgatctgc atcagtttat caatggtcac gcgctcagtg
    10621 gaaaccgcaa tataaatcga ggataggcgt ctgcgctcat cacttttcat gacataatta
    10681 taatcagtca cttcttctaa taataagcga caagcagctt tttgatcagc tgttaaaaga
    10741 atgccaagtc taggataaga gataatctga tctactccct ttggcaaagc ctgattaatt
    10801 ttgtcaagct ggtaataaac tttacgacgt gactgattta aagcatgaga aatggccata
    10861 actgtctcag gtgtttctag tttaagtaaa taagacagca agtcataact ctttttatct
    10921 aaaatcatca tgtttacaaa cctcctctct gaaaatccat ccttgcttat tttatcatga
    10981 tttcagtgac tgcgcagcca agttttgaaa aactcaccat aataagattc gcttaatatg
    11041 attcgagcta atcacctcaa ctgatccaac accaacacct tatatctggt ctctaagaac
    11101 tccacaacat acgattcatc cagtttgtgc tcattggcgt ttaaatagtt catcgaaaag
    11161 gacaagtcaa aaggacttgc ccaaacaatg attaacaaaa ccttgaactt tctggcttct
    11221 agtgagaacc tgtgctaata agccatatcg tgacctcatt tttgaccgta ataagcattt
    11281 gggccatgtt tacgcaaata atgcttatcc ataatgtatc gtggcgctgg ctctacgcgt
    11341 ggattgattt gttctgtcaa gcgattcatc ctagccactt cttctaagac aaccgagtgg
    11401 taaacggctt gctctggggt tttcccccac gtaaatgggc catgattgcg aaccacgatt
    11461 cctggaaccg ccataggatc taagcctcgc ttgctaaact cttctaaaat cacgttgcca
    11521 gtttcttgct cgtaagcccc atcaacttct gcttttgtga gagaacgagc acacggaact
    11581 ggtccataga agtagtcagc atgcgtagtc ccataaaacg gaatatcacg acctgcctga
    11641 gcccaaccaa cagcttctgt ggagtgagtg tggacaatac cgcccacttc tggccaagct
    11701 ttataaagtt ccacatgggt tggcagatct gaagaagggt tcaaatcacc ttcgaccaca
    11761 ttcccatcaa ggtctgtaac aaccatgttt tctggtgtca agaggtcgta gtccacccca
    11821 gaaggcttga tgacaatacg tcctaattca cgacaaactt cagagacatt gccccacgta
    11881 aatttgacaa gaccgtgttg tggtagagac ttgttagccg cacagacacg ttcacgcatt
    11941 tcttgcaagt ttttcgccat attatgccaa ccccgctttc tcaataagtg ggtaaaggaa
    12001 gtcctgagct tctttgatag cagcttttgt ttcctccacc gtgtcacaat tttctgacca
    12061 catttcaatc aaaaaaggcc cattgtagtt ggttttcttg aggaccgcaa acagctcttg
    12121 ccagtccaca caaccttgac caaatggcac atcacgaaac tgcccttttg aggtttccgt
    12181 gacagcataa gtatctttca agtggagggc tgcaatggac ttgtgaccat tgtaaaattc
    12241 actccacaaa tcattatgcc aggcagaaac attgcctgca tcaggataaa caaagagata
    12301 aggcgagtca atctcttttt caactgccaa gtatttttca atagagttga taaaagggtc
    12361 atccataatc tcaatagaaa gcatcacttg ggcttcttcg gcccagtcac aagattgtct
    12421 caagtttttg ataaaacgag cacgggtttc aggcgatttt tcttcatagt aaacgtcata
    12481 accagctaat tgaatggtac gaacgcctaa gtcctgtgcc aattcaatac attgtttcat
    12541 cagtttaagg gacttggctt caatagcagg atcatttgag cctagtgggt aacgtctatg
    12601 accagaaaaa caaatggtcg ggatgcgaat gcctgtttca taaatggctt tcactaaatc
    12661 aagccgttct tccttagtcc actctaagcg cgctaagcga gcatctgatt catcaacaga
    12721 catttccaca aaatcaaaac ctaagtcttt tgcaaattgc aagcgttcac gccaggtaaa
    12781 ctgttttggc gttgcttttt cataaatacc aataggacgc gccataaagt tacccccaga
    12841 tacgtttgat ttcatctttg aaggcacgcg ccgctgcagc aggatcttct gcttcagtaa
    12901 tgcctcgccc tgcgataaag gtaaagacat caaccccttc aaaaagtttc aaagtgtcta
    12961 catcaagccc accagttact gacacgcgga agcccatgtc aatcaatgtt ttcaccttgt
    13021 taaggtcttt ttcaccccaa gtttctccag caagaagggc atcacgtgat tggtggtaaa
    13081 tggcttggga aatcccagcg tcaagccata attgagcttg ctcataagtc caatcaccat
    13141 aaagttcgat ttgaatttcc ccacggtcac cgcgctcttc tttcatagcc ttgagggctg
    13201 cttccatggt tggaatcgtc gcacagcaaa tgcaggtcat ccagtcagca ccacgttttg
    13261 cattgttttt agcgaccgta ccgccagcgt cagcacattt ggtatctgct acgataattt
    13321 tctctgggaa gaggctgcgt aatacctcaa ccaactcgct tccgacttga agcaagcaga
    13381 ccgtaccggc ttcgataacg tctacttcgt gacccacagc aacggctgct ttaacagccc
    13441 cctgtaagtc agaatggtct aaagcaactt gtaaatttgg aatatgtgtc atctcttttt
    13501 cctaaaactc ttagccaccg tgcaaactgg ttaagagttc ttatcctttc catcattcgt
    13561 tagtatcctg tgtaaggaaa gcttaagcat tcaagtccat accttctaag taaggactat
    13621 ctttagattc ttctaccatt tctagaacct ctttaggact ttggcaggcc accaagcgtt
    13681 caatggcgtt atctagttca aacaaggcca caatttgtgg gatagccact gttgtgtgaa
    13741 tagaagggtc tgtagcggcc aacgtcaaaa gaacagaaac ctctttacca tctgagaagg
    13801 taactggttt tgttagtgta accaaagcaa atgcattgcg attaacgcct aaacctgctt
    13861 ctgcatgggg catagccata cctggcatca acacataata agggccgtat ttttctgttg
    13921 atgcaatgat ggcgtcgtag taagctgacg tcactgcttt gctatcaatc aaaggttgaa
    13981 cagctaattg aacagcctct tgccaagtat cagcacttag ccccaatcgg atggagttgt
    14041 tgtcaataaa ggcttgtttt aaattcataa aaactatctc tttctagtgt cttgctttgc
    14101 aacacacacc atttttacta gttttatcct actaaagaga aagagctgaa aaccttcgtc
    14161 acaactcctt cgttttgatt cagaattagc ttatagcact tcttgtagtt tggttttaat
    14221 ttcattatca tccatcaggt tatcaagacc aaccaagtgg cctttggtac gaccatcaag
    14281 ctcatgaatc aagtgatttg atgccactac aatatcatag ccagaagcta gacctttagc
    14341 ttcaccaact gagcaagaag ctgactgaat atctgtcacg ccaagttgac gaagcgcatt
    14401 ttcaactttc attttgatca ccatagatga ccccatacca ttgccacatg ctgttaagac
    14461 tttaaccatt gttttttcct ccgaaaatgt tttattattg ttttgttaaa atagcagagc
    14521 tatttcttaa gatgcagtgt tattgagctt ccccacggta ataagcttct ttgtccttag
    14581 cttttgcgaa ttgcaattgt ggaatggcaa gtaagaagat gcaaacaagc acataccctg
    14641 caataccaag gaatttgaag aggtacccaa atggtaacca tggaagaacc aagtcgatat
    14701 taccgtgata accacctgta agtcctaaaa gacctacagc aacagcacca agtgcaactt
    14761 gcaaaatacc tgaaataaat gatagagcta ccgctgcttt ccagccacca cgtttatctg
    14821 cataaaccgc aattgccgca ttatcaaaga atacgggaac gaatcctgtg ataattaaga
    14881 ttggattttt aaagataaca agaagagcaa tggtgattaa ttgaccaatc aaaccaaagg
    14941 caaatcctga aagcaccgca tttgaagaac caaagccata ggaagctgca acgtcaaccg
    15001 ctgggaatga ccctggaagc aatttgcttg agatcccttg aaaggcattg gtcaattcag
    15061 aaacaaacat gcgaacaccc tgcatcaaga taaagagata aactgagaag gtgagagagg
    15121 tttgcaaaat atacatgaag aaagcttgct tagctgggtt gaatgctcca ggtccgatta
    15181 agtccacatc agacataatg tctggaccaa ggacagccaa gatagctccg aaaaagacca
    15241 acatcaaagt tgctgacgca acaacagtat catggaaaat gtttaagaag gttggtaatt
    15301 ttaggttatc aaggttttct tcttttttac caaagaacgg tgcaacctta tccacaaacc
    15361 aaatcgcaaa ttgttgttgg tgaccaatcg caaacccacc gccacctgta aggcgttgag
    15421 ttgcttcaac ggtcatgttt gagctgatag cccagtaaag cccacagatg ataccgactg
    15481 cccatgcccc aaaagcattt tggaattgag ggattaaaag aaggacaaag accgaaatcg
    15541 tcgctgcctg ttggaccatg atgtgacctg tgatgaaaag ggtacgaact ttagtgacct
    15601 tgcgaagtgc aaccaaaaga atgttgaccc caaatccaat caagagagct gtcgtagcaa
    15661 cactgatgaa gcccatctct tctaacttag tattagcagc agccaaacca aaataaggat
    15721 caataacggc ggctttcaat tcaaatttct tggcaagagc aaccaagatc ggacgaaaag
    15781 tcgttacaag accgcctgct ccaacgttca aaatcaagta accaacggta gcctttacaa
    15841 aaccagcaaa gacctcataa atgggttttt taaggagtaa atacccgatt aaaaccaaaa
    15901 gacctacaaa gaacgctggg ttttgcaaaa tattttgcga gaaccagttt aggggagcta
    15961 ggagcatttc cataagaact acctcttttc aaagttaata aagataaagt gtttatatgt
    16021 tcattatagg taatgaaagc gttttaaaaa agaccaacta tcacacaaag aagtgttcaa
    16081 tattagactt aagttaactt attttaaaat ttaactacac ttaataataa ggagaaaatc
    16141 accctaaaca acgattaaaa accacaagaa ccttcgttct tgtggttttt ctagatgagt
    16201 tgctttttga atagatcagc tctttggcat taactgtgac gtgacgcaaa taaccactga
    16261 agggctgtgt cacctcaaac tatttgataa caatattaac gagtttgttt ggtactgcga
    16321 tgactttgat gatgtctttg cctgcgattt cggcttggac tttttcgtta gcaagggcaa
    16381 cttcttgtaa ttcttcgcgt gaaaggtctt tagcaactac aagtttagct ttgaccttac
    16441 ctttgatttg gacaacgatt tccacatcgt tttcaaccaa tttgctttca tcataacttg
    16501 gccatggcac gtaagagatt gactcacctg aggctgtcaa ggcttgccag agttcctcac
    16561 ctaagtgcgg tgcaaatggt gcaatcaatt gaacaaagcc tttggcatag tcgctaaaga
    16621 gtttgtcttc cttgttggct gcattgacaa ataccatgag ttgagcgata gctgtgttga
    16681 atttcatttg gtcaacttgc tcagtaacgg ccttaacggt ttcgttgtaa accttgtcaa
    16741 gggctccgct attttcctca gtgatctctt tagtcgtgat caaacggtaa acacggtcca
    16801 agaacttacg tgagccttca agaccttctt cagaccaagc gatggaagcg tcaagtggtc
    16861 ccatgaacat ctcgtaaaca cgaagggtgt cagcaccgta ctgctcaaca acatcatctg
    16921 ggttgacgac gttcttaagt gatttagaca tcttagctgg tgcttgttca agctcttccc
    16981 cagtttccac atggaagaag ctgccatcac gtttttcaac cttgtcagtc gctacaagcg
    17041 ctccacggct atcgcggtag cttgtcccca aaatcatccc ttggttaaag agtttttgga
    17101 atggctcttt ggtaggtaca acaccgagat cgtaaagaac cttgtgccag aagcgagcgt
    17161 agagaaggtg aagcacggca tgctctgcac caccgacata gatatcaact ggcaaccatt
    17221 gtttgaggag ttcctcatca gccagttttt cggtgttgtg tggatcgatg taacgaagat
    17281 aataccagct tgaacctgcc cattgtggca tggtgttagt ctcacgacga cctttaacac
    17341 catcttcacg ggtaacttcc aaccagtctg tcacgttagc aagcgggctc tcaccagtac
    17401 ctgaaggacg aatatcctta gttactggaa gaaccaatgg caattcactc tcaggaaccg
    17461 ctgttgatgt cccatcttcc cagtggatga ttgggattgg ctcaccccag taacgttgac
    17521 ggctaaagag ccagtcacgg agacggtaag tgacattttc attaccgacg ccttctgctt
    17581 caagccattc gaccattttg gcaatagctg acgctttgtc aagaccatct aggaagtcgg
    17641 agttgatgtg aagaccgtct tctgtaaagg cagcctcttc aacattacca ccttcaagaa
    17701 cagggatgat gtctaggtta aattgttttg cgaattccca gtcacgttca tcgtgggctg
    17761 gaacagccat gatagcacca gtaccgtagc tagcaaggac atagtccgca atccaaactg
    17821 gcatttcttt gccgttgacc gggttaatcg catagctacc cgtccagaca ccagtttttt
    17881 ctttggcaag gtctgtacga gcaaggtctg atttgagact tgcttgacgt ttgtagtcag
    17941 ccacggcttc tgcctggtca gatgtcgtaa tagcatcaac caaggcatgc tcaggagcaa
    18001 gaacggcgta agttgcacca aaaagcgtgt caggacgtgt tgtaaagaca gtgaagtcct
    18061 tatctgtatc cttaaccttg aaggttacat tagcgccagt tgatttacca atccagttgc
    18121 gttgcatgtc cttgattgat tctggccagt caacttcttc caagtcttct agcaagcgct
    18181 ctgcataggc agtgattttg agcatccatt ggcgcatggg ttttctgaca actggatagc
    18241 cgccacgttc tgatgtccca tctggaagaa cctcttcgtt ggcgatagct gttcccaatt
    18301 cttcaaccca gttaacggga acttcagctt cgtaggctag acctttttca taaagcttgg
    18361 taaagatcca ctgcgtccac ttgtagtagt tagggtcagt tgtgttaact tcacggtccc
    18421 agtcgtatga gaagccaaga gcattaatct ggcgtttgaa gttagcgatg ttttcagctg
    18481 taaactcggc tggatcatta ccagtatcca tagcgtactg ctcagcagga agtccaaagg
    18541 catcccaacc cattgggtgg aggacattgt gaccttgggc acgtttgaaa cggctaagaa
    18601 tatcagttgc tgtatagcct tctgggtgac caacgtggag accagctcct gatggatatg
    18661 ggaacatatc tagggcataa aacttaggtt ttgatgcgtc tgttcctgtt ttaaaggtgt
    18721 gattatctgc ccaaaaggct tgccatttgg gttcaatagc ggtgtgatcg taaaatgtca
    18781 tgtgaaatct cccatgtaaa aaatctagtc ttcttattat agcatgagat gaagctttta
    18841 ggaatggtca agacatgact agcaccttgg cttttgagac ttcagacgat tagctatttt
    18901 taaaccctgc tttagcatca accatcctca caaaaagcta ataaaaaagc cagacttgct
    18961 ctgtaaacag agccaatctg gacaaataga cttaaaaagc aagtgcttgc tcaaaatcgg
    19021 ccaataagtc ttcgatattt tcaacaccac aagacaagcg cagcaaacca tcaacaaccc
    19081 cttgttccaa ccgcgcttgt gacgataaac aagcatgaga catcgttgct ggatgtgaca
    19141 aaatggactc tactccacct agactaacgg ctaaaatcgg caactgaata cgatgggtaa
    19201 aggacatcag ctcctcctta gaagccaact caaaggataa aacagcacca ccattcttag
    19261 cttgttgcag gtgggtatcg tgattaggat gactgtctaa gccagggtaa tgtaccttaa
    19321 gaactttggg gtgcttcgct aaatagttag cgagctgctg agcatttttt accgcttgtt
    19381 ccatacggat ccccatagtt ttcatgccac gaagaatcag ccaagcgtct tcgaccccaa
    19441 caattgctcc aaagtttttt tgaaaaagct tgagctggtt gtagatagcc tcattattgg
    19501 tagcagctaa accagctacc acatcactat gaccattgat aaatttggtc acactttcta
    19561 ctacaatatc cacacccata gctaagggtt cttgatacaa actggtcata aaggtattat
    19621 cagccacagt tagcacacca taagctttgg cgagttgcgc aagctctgaa atatcacaaa
    19681 ttttcaagag cggatttgac ggtgtctcta gataaatcat acgcgtatta ggcctgatac
    19741 ttgcttttac tgttgctaaa tcagccatat ctacaaagct tgtttcaatc tgataattgg
    19801 gtaaaatagc tgtcgcaaat tgacaagtcc ctccatagac ctccaatggg aaaatcacat
    19861 gatctccagc ttttaagagc atcaaaacag ttgaaatagc agccatacca gatgcataag
    19921 ccaccgcata agtcgctttt tctaaacagg ctaacccgtc ttctaaagct tcagtcgttg
    19981 ggtttgaaaa gcgtgtgtac aaatgttttt gactaggaca atacagttct gaattgtgga
    20041 acgtcgaagt ctgatagatg ggaactgaag ctgctcctgt aaactcgtca ataaccgtat
    20101 agccatgtaa taaggtcgta ttttctctca tttcgtgcac ctccgcaata gcgttaactc
    20161 caatgaactc tcttttagac aatggtccca ccccaatggt tgcacaaacc aaaaagctct
    20221 tcaaaaaagc gtgatctgct aacctataag aaaaataaag aaaagtagtg ggcacctttt
    20281 aaatggataa tgaatttttc caataatatc atttttagat cgattacgtt tattatacaa
    20341 cctttagcta agtttgcaag cccttttatc atctttgacc aagctgccaa cacctctcca
    20401 gcaagttaaa gtatagctac ctttggcccc atcgtctcaa aagctcaaat tatcacactg
    20461 acagtcctac cttgcatcgt cacctactca atatggcaat actgccatca aaatttcatt
    20521 aaaaggtcac aatttatttc atttaatgag aaacagaact tgttttcacc atgcgtctta
    20581 tagtataccg ctaaaatact atttattttt aggagagaaa tatagtgaaa aacaaattat
    20641 ttttagttgc ccttgcgacc gtaactgtcc tagggccctc tttagcaacc cctcatcatc
    20701 agaccgtgca tgcggctgag caggcaaaag aaccccaaac cagctcaatg acgtgtacta
    20761 acgatggatc tgtatgcgct ggctggcata gtttatcaga aggagacagt ataacttcaa
    20821 attcatcttc aaacaccaag acttccctgt taaactggtt atggagctta ataacaaatt
    20881 tgtggaattc tgcaaaaaac ttgttcatct aagatctcta taatcatatc catggaattt
    20941 aaataaccat ctcgtggcgg ttttctaatc ctaggtcgcc acacttctta ttcagataaa
    21001 taataataaa aacattaaaa taacacttta tttattaaca aaaagttagt ataatataat
    21061 cacaatacaa attaaaggag tta
//
LOCUS       DAUGJR010000034        20957 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUGJR010000034 DAUGJR010000000
VERSION     DAUGJR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20957
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.034"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            35..670
                     /locus_tag="VH800_001298"
     CDS             35..670
                     /locus_tag="VH800_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEQ8362366.1"
                     /translation="MIKIDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYE
                     TDVSYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQA
                     WQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEWIGDGIEHIENPLIEWI"
     gene            938..1357
                     /locus_tag="VH800_001299"
     CDS             938..1357
                     /locus_tag="VH800_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ8362367.1"
                     /translation="MSKAKAILKDLRNLDLYIASLIRRRDKIEASLLSSPKWSSDKVN
                     GGIKRKQDDVYVELIATAKDIEKKTAEAIRKQRELQNLIDSLENTDSQTILSMVYIDK
                     MTRWQVIDELNCSESTYFRLLRVATKELNNLTVNDSD"
     gene            1466..1810
                     /locus_tag="VH800_001300"
     CDS             1466..1810
                     /locus_tag="VH800_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEQ8362368.1"
                     /translation="MSQLRADKKGTHRVAFDRNKKKLLKAATVCGICGKPVDKSLKYP
                     HPLSAAIDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRNLP
                     QSRDWSSFAFKK"
     gene            1959..2315
                     /locus_tag="VH800_001301"
     CDS             1959..2315
                     /locus_tag="VH800_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362369.1"
                     /translation="MKKKCLICKKNFQAKTNRTLYCSEECRKKGNREKQRKLMKQKRA
                     EQRKEKKKVLNPNTDVTEKPKKIRNLAQHYKKLKKEILANESEFGFTGITLIEGIDVH
                     EENFVDLVMQKIKEQK"
     gene            2312..3580
                     /locus_tag="VH800_001302"
     CDS             2312..3580
                     /locus_tag="VH800_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8362370.1"
                     /translation="MNYMGMGYLRRKLALFKTGVDKRYRYYAMDDRDDTRSIVMPNNV
                     REMYRSVLEWTAKGVDSLADRIIFREFTNDDFNAWEIFKANNPDIFFDTAIQSALIAS
                     CCFVYIMSGAEDGLPKMQVIEASKATGILDPTTFLLTEGYAILESDSNGNPTLEAYFT
                     DKDIWYYPKKGKPYNIKNPTGHPLLVPIIHRPDAVRPFGRSRITKAGMYHQKAAKRTL
                     ERAEVTAEFYSFPQKYVLGMDPDAEPMEKWRATVSTLLEISKDEDGDKPTVGQFTTAS
                     MAPFMEHLKMYASLFAGGSGLTLDDLGFPSDNPSSVESIKAAHENLRAAGRKAQRSFS
                     SGFLNVAYIAVCLRDEFPYLRNQFMDTVIKWEPLFEADANMLTLVGDGAIKLNQAIPG
                     FMDADVIRDLTGVKGADKPIPAITEVTTDG"
     gene            3573..5066
                     /locus_tag="VH800_001303"
     CDS             3573..5066
                     /locus_tag="VH800_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362371.1"
                     /translation="MVDDVLPKLLKSVRQDFEKYFGESDVVTKAFAELQAKKVTYKTV
                     NEFAIEVGRLLSLALTGSVSSDKLPDGKMYYNIAKRLLDETMGRNYKLISGYAGDVQR
                     ILNENAQIGLKVQRPPLNRDKINRMVNRLDSENTFDDVKWLFGEPIVNFSQSIVDDTI
                     KANADLQYKTGMTPQVVRTESGNCCEWCREVVGTYSYPKVPKDVWRRHQRCRCTLDYD
                     PKNGKVQSAWSKIWRKKEKTQESIERVEKFKESALVESIKNDIAKLDMTKVGPSDIID
                     IGKRINYHFRVSEHIGDKEKLKEIFSNFREIGGEIPKNTWAKGSSKLVKDQLQEAFQN
                     YPTEWAAVPDGIGKKLKAIKRKRGYFDGYDEDLVIATNGTRKTTPYHEIGHMIELVNP
                     DLVRLEKAWVDKRTANEAEVRLKDIFPSSNYGIGEVTKKDDFISPYIGKYYSDAAEVF
                     TMGLQGIFVPEERFAKSFDKKTWKYDYKTINDDPEFLNFIIGLFVKV"
     gene            5072..5296
                     /locus_tag="VH800_001304"
     CDS             5072..5296
                     /locus_tag="VH800_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362372.1"
                     /translation="MEPKLHRQLRQKYDDAEKQYLEKFGEDSLDRVFFWEPDVYFDEW
                     KKVLPDATLELNKAINSGVAIGPDPENAIY"
     gene            5346..5525
                     /locus_tag="VH800_001305"
     CDS             5346..5525
                     /locus_tag="VH800_001305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362373.1"
                     /translation="MNKISLNVEMTWENKDEFQQIMNKVNETKEAYEKALEAAENFVP
                     KMSCATKLNKGEGDE"
     gene            5518..5784
                     /locus_tag="VH800_001306"
     CDS             5518..5784
                     /locus_tag="VH800_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362374.1"
                     /translation="MNKRIKKKRKLERAIVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQSAIADIAIDVNYIKKNYKRKWGK"
     gene            5894..7309
                     /locus_tag="VH800_001307"
     CDS             5894..7309
                     /locus_tag="VH800_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ8362375.1"
                     /translation="MVTKTKTKLGNQRPTQSVNLHFAKSLAHEAINYYKKTGLSCYPW
                     QVNMLIPIMAIDENGLWVHQKYGYAIPRRNGKTEVVYIVELWALHKGLKILHTAHRIS
                     TSHASFEKVKKYLEMSGYVDGEDFISNKAKGQERIEFKASGAVIQFRTRTSNGGLGEG
                     FDLLIIDEAQEYTSEQESALKYTVTDSDNPMTIMCGTPPTMVSTGTVFEAYRKDCLKG
                     NKRYSGWAEWSVPEMVKINDVSSWYISNPSMGFHLNERKIEAELGEDEIDHNIQRLGY
                     WPSFNQKSVISEKEWAKLKVEQVPELKSKLFVGIKFGQDGNNVSLSIAARTSENKVFV
                     ETIDCLSVRNGTQWIINFLKSADIAKVVIDGASGQELLAQEMKDQGLKKPELPKVAEI
                     ITANMMWEQGIMQETICHSDQPSLTAVVTNCEKRQIGSNGGFGYKSLYDDRDISLMDS
                     ALLAHWICYTTKPKRKQRTSC"
     gene            7390..7851
                     /locus_tag="VH800_001308"
     CDS             7390..7851
                     /locus_tag="VH800_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8362376.1"
                     /translation="MSEFKVIETQEELDTIVKARIAREREKYQDYDQLKTRVEELETE
                     NSSLQTALNDAKSNTDSYTEEISTLKNQIADYEAANLRTKVALQYGLPIDLADRLQGD
                     DEDGLKVDAERLASFIKPSQPQPPAKSNEPNIDSNADANYRALVQGLSTED"
     gene            7876..8787
                     /locus_tag="VH800_001309"
     CDS             7876..8787
                     /locus_tag="VH800_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEQ8362377.1"
                     /translation="MGTETSKASLFDKHLVSDLINKVKGHSSLAKLSSQKPIPFNGSK
                     EFTFTLDSDIDVVAENGKKTHGGLSLEPVTIVPIKVEYGARLSDEFLYATEEEKIDIL
                     KAFNEGFAKKLARGIDLMAMHGINPRTKKASDVIGTNHFDSKVTQVVKFTESEDADAN
                     IEAAVNLIQGSEGVVTGLAMDTEFSTALAKVTNGEMGPKMYPELAWGANPDSINGLKS
                     SVNTTVGAGADEAESKDLVIIGDFESMFKWGYAKQIPMEIIKYGDPDNSGKDLKGYNQ
                     IYLRAEAYIGWGILDAKSFARVTKGEV"
     gene            8787..8987
                     /locus_tag="VH800_001310"
     CDS             8787..8987
                     /locus_tag="VH800_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362378.1"
                     /translation="MLYVNSKTGASFYSSVPVCGGDWTLVEQQTGEKAKTVAEIKRQL
                     DAAGIKYSSKAKKPELEALLPG"
     gene            8997..9419
                     /locus_tag="VH800_001311"
     CDS             8997..9419
                     /locus_tag="VH800_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage Gp19/Gp15/Gp42 family protein"
                     /protein_id="HEQ8362379.1"
                     /translation="MGNFATTDDVILLWRPLSVDELKRANALLKVVSDTLRMEADKVG
                     KDLDKTMVDKPYFVNVIKSVTVDIVARTLMTSTRGEPMAQESQSALGYTWSGTYLVPG
                     GGLFIKDSELKRLGLKKQRYGGIELYGEIERDNSCFSR"
     gene            9379..9717
                     /locus_tag="VH800_001312"
     CDS             9379..9717
                     /locus_tag="VH800_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362380.1"
                     /translation="MAKLKGITVALADKSISGKDPFGNPVTVDFDIKIENVLVAPATT
                     EDITNQLSLTGKKVEYVLAIPKGDEHDWENKEVRFFGKKWRTVGIPLEGIEELIPLDW
                     NKKVMVERYE"
     gene            9710..9946
                     /locus_tag="VH800_001313"
     CDS             9710..9946
                     /locus_tag="VH800_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362381.1"
                     /translation="MSKFKFKLNRAGVAELMKSSEMQQVLTTKATAIRERCGDGYVQD
                     IHVGKNRANAMVSTKTIKAKKDNSKNNTLLKAVR"
     gene            9947..10282
                     /locus_tag="VH800_001314"
     CDS             9947..10282
                     /locus_tag="VH800_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362382.1"
                     /translation="MIEVIIKKYLDEHLDVPSFFEHQEDEPARFIILEKTSGAKQNHL
                     LSSTFAFQSYAESLYEAALLNDKVKQVIEQLDVLPQVSGVHLNADYNFTDTATKRYRY
                     QAVFDINHY"
     gene            10294..10887
                     /locus_tag="VH800_001315"
     CDS             10294..10887
                     /locus_tag="VH800_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8362383.1"
                     /translation="MNKNDTKNVTSAKPKTGGAIYSAPLGTELPKDAKSELNTKFKNL
                     GYVSEDGVVNEDTRSSENIKAWGGDIVGAVQTEKEDKFTYKLIESLNVEVLKEVYGAV
                     NVTGDLSGGIQIKSNSKELEAHVIVVDMIMNGGILKRIVLPNAKVDEVGEIKYVDGEV
                     VGYETTLKCFPDKDGDTHREYIVKPGEANKKENSFEM"
     gene            10898..11161
                     /locus_tag="VH800_001316"
     CDS             10898..11161
                     /locus_tag="VH800_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362384.1"
                     /translation="MEILKGKTTSGFEYEIPKKRLKNFELVEAIAEEETDPTAVVKIV
                     NLLLGDAAKSLKEHVRDAEGIVDVEAIGVEIKEIFESQKDLKN"
     gene            11176..11547
                     /locus_tag="VH800_001317"
     CDS             11176..11547
                     /locus_tag="VH800_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5361 domain-containing protein"
                     /protein_id="HEQ8362385.1"
                     /translation="MIAKDDDALTCDLAETYGIYDYRQLPAYQVAVFAVGLRSNSRIK
                     MALSGETEALDTVLLAGIYDNTNLLFWSKTKDGQSGQNKPKSVVEAISGSKSQKANDV
                     ISFVSGEDFENARKQLLGGDG"
     gene            11547..13904
                     /locus_tag="VH800_001318"
     CDS             11547..13904
                     /locus_tag="VH800_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362386.1"
                     /translation="MATELGQAYVQIMPSARGISGAISKQLDPEARSAGLSAGSLIGG
                     NLVKMIGGAIAAAGIGKMISSALSAGADLQQSFGGIDTLYKGAETAVKGFAKEAYKAG
                     ISANTYAEQAVSMGASLKQSLGGDAVAAAKAANMAIMDMADNSAKMGTDITSIQMAYQ
                     GFAKQNYTMLDNLRLGYGGTKEEMKRLLSDAEKLPAAMGKKFDLSNYADVVEAIHLVQ
                     DNMGIAGVAAEEAKTTFSGSLAAMKSSFTNVMAGLSLGDDIRPALRGLAETTSNFLFG
                     NFIPMVANIFKGLPSAIGTFIGAAAPIITSQFQGLMSSLGISIDLSPITAKFAQIGQN
                     LQPVFNGLKTAFSQLPSFFTSIGSAVAPVIDTIISGLARLDFSGFEALISAILPALQA
                     GFSNFAAIVGPAISGVVDSFVGMWNAAQPLISILSDALMPVFQILGSFLGGVVKGALM
                     GVSFAFDAVKVAIQLVTPIIDLLVQGLNFVQPVLSVIAEWIGVAIGMFGNLGTAGQGL
                     SAFIKSAWTNIQTAISTAGTIISTVIDYIKLAFSGAGSAVGVLKNIFSLAWMAMGDAI
                     NVAKGIISSVINGIKSAFSSFSSLVSSVGSAVNGVIDSISSTIRGLANIDISGAGAAI
                     MNGFLNGLKSAWGAVKSFVSGIANWIAEHKGPISYDRVLLKPAGKAIMGGLNTSLIDG
                     FKEVKSNVSGMADDLASTMTGKSLSLGIDAKPSVTADDLLSSNISTKTTVGSATSDLS
                     LFFVKVLALLQDILDKNTDVYLDKEKVSAILYEEFAKIMAREGIV"
     gene            13901..14596
                     /locus_tag="VH800_001319"
     CDS             13901..14596
                     /locus_tag="VH800_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362387.1"
                     /translation="MIPKVIIDDFDTSSIPNCVLTGYDVGDILSPSFVENEAYGMNGT
                     SRELESYNESKPTIMWHLSTFDDAVNLINHLDGLSKKIEFWHIPNSIYYYDCLSVKIN
                     AVTMSSWRVTLKLALYPFRYAKGVSDVVIAGNGNINNAGNVFSEPKIVVEGTGKGTLT
                     IGKQVMELNLSGKATIECKHGQQCVYDAEGNVKNSIRIRGSFFEIQPGTQGIAVSGGI
                     TRTIISPRWRYKV"
     gene            14593..16461
                     /locus_tag="VH800_001320"
     CDS             14593..16461
                     /locus_tag="VH800_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362388.1"
                     /translation="MISIKDDNTPLVAAFEDEITQEANSDYKLNFKYPAKHEYRPLIK
                     KGIILEADDLHGSQLFRIFEITKRHGYINVYANQVADDNTMHDFVKPKVTTQQAFGLA
                     QQVKELDLQLKDPKSDLWGKIKFNNKAMLVEYANKEMSSAIAQSAEQILLQVKSIDDE
                     RYSKFEQTLNGIKQTVKSESVESARTQLASMFDSRISGLDGKYSRLSQTIDSLSSRLD
                     DGVGNYSTLSQKVSGIDLRVSNAANDVSRLSQTAQGLQSQITNANQNYSSLSQTVQGL
                     QTTVRDNQSNATSRINQLSNLISTKVSKGDVETTIAQSYDKIAFAIRDKLPASKMSGS
                     EIISAINLDRSGVKITGKNITLDGNSYISNAVIKDAHIANMDAGKINTGYLNANRIAT
                     EAITGEKIKMDYAFFNKLTANEGYFRTLFAKDIFATSVQSVTLSASKITGGVLAATNG
                     ASQWDLNNANMTFNRDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYRGSALYASI
                     GITSSGDGIDSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFSINRGFK
                     FRPHKMEKVLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVSRELNNYITKI"
     gene            16473..16910
                     /locus_tag="VH800_001321"
     CDS             16473..16910
                     /locus_tag="VH800_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ8362389.1"
                     /translation="MQLTIKNKDLNTLYRVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            16907..17524
                     /locus_tag="VH800_001322"
     CDS             16907..17524
                     /locus_tag="VH800_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8362390.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIIAAEDGAVIPQLVKKDLTG
                     TNDKDIITAVLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHMLTSGGKIDPDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEAFEYDKQTLEELESEAKVTVIKYADLVKQD"
     gene            17534..17809
                     /locus_tag="VH800_001323"
     CDS             17534..17809
                     /locus_tag="VH800_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362391.1"
                     /translation="MATELIFGVGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHAEQNKTLITMTEQIKNLTDDVKDLKDMMRGEIK"
     gene            17806..18033
                     /locus_tag="VH800_001324"
     CDS             17806..18033
                     /locus_tag="VH800_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEQ8362392.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            18149..19354
                     /locus_tag="VH800_001325"
     CDS             18149..19354
                     /locus_tag="VH800_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8362393.1"
                     /translation="MTFLDKIKQGCLDGWTTYKILPSLTAAQTILESGWGKHAPHNAL
                     FGIKADSSWTGKSFDTKTQEEYQAGVVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYQ
                     AVIGETDYKKACHAIKDAGYATASGYAELLIQLIEENDLQEWDEEAIVRKEKQMISSQ
                     CREVIEFFINLVNAGVGVDKDGFAGWQCTDVPCYAAKHWFGVDLWGNAIDLLDSAAAV
                     GWEVHRMPTDANPQTGAFFVQSVPYHQFGHTGVVIEDSDGYTMRTIEQNIDGNPDALY
                     VGAPARFNTRDFTGVTGWFYPPYQGDIVTQPVSTEPQTSDTIVETAKTGTFTLDVAEI
                     NIRRWPSLTSEVVGSYKQGDTISFDSEGYANGYYWISYVGGSGMRNYTAIGITDKDGN
                     IISLWGKLN"
     gene            complement(19424..19858)
                     /locus_tag="VH800_001326"
     CDS             complement(19424..19858)
                     /locus_tag="VH800_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362394.1"
                     /translation="MKRSKKASLLSVIVGMALAVIPIYIVNYDNELIVLLMSIFFNGI
                     IVSAFELIKTYDGLQEEYKKLTVDRWKNTILLAFNSLYFASILTNSLSNNLSTILSTN
                     RSDKVSAIFLTGCSILALLPFLLHRLIKREIEIENERKKLKK"
     gene            complement(20129..20929)
                     /gene="sda3"
                     /locus_tag="VH800_001327"
                     /gene_synonym="mf3"
     CDS             complement(20129..20929)
                     /gene="sda3"
                     /locus_tag="VH800_001327"
                     /gene_synonym="mf3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase Sda3"
                     /protein_id="HEQ8362395.1"
                     /translation="MSKSNRRTWQGLVVILIAILTTFTTSTVTAARKIRNFPDTTEIL
                     LGTKATETPGILPFTGSYQLVLGDLDNLQRPTFAHIQLKDQDEPNIKRKGLKFNPPGW
                     HNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDSWLALHPNFWLDYKVTPVYHKNELVPRQVVLQYVGIDENGDLLQIKLGSEKES
                     VDNFGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNLETEEFEEAA"
BASE COUNT         6990 a         3574 c         4551 g         5842 t
ORIGIN      
        1 cgaattgcgg aacttacgca caacggaggg taacatgatt aagatcgatg agatacatcg
       61 catactaggc atcgacgaag tttataaagc acccaaacga cttacggaca tactctttga
      121 taaagatagt cgtgaggata tatttagaca gtttttgaaa tatgaaacag atgtatctta
      181 cgactggttt atgcaatatt ttgaggaaga acaagctgac cgcaaaaata aaaagcaaga
      241 ctttacgcct aaatcggtta gtacactatt atctaaaata ataagtggta atcaatacta
      301 cgaggtagca gtcgggacgg gtgggatact tatccaagca tggcaagaac aacgattaaa
      361 tgacagtcca tttacttatc gtccgagtaa atactggtat cacgtagaag agttatcgga
      421 caaagcagta ccgtttctac tctttaatat gtctataaga gggataaatg gtgtggtggt
      481 gcatggcgac tctttaacaa gacaagttaa aaacatttat tttttgcaaa atacaaaaga
      541 cgacatgctg agttttagtg atattaacgt tatgccaagg actcaagata ttgagcgaga
      601 atttaatgtc aaagagtgga ttggtgatgg gatagaacac attgaaaatc cactaattga
      661 atggatataa ccaataacgg tatcacgcac gttcgactcg tgcggttggt attgaccgaa
      721 attaaaaaat agaaacgaga acctccttac accaaaacaa aatctaacgc tggttatcgg
      781 tcactggcta ttatttaagg cgctaatact gacatcctgc gcctgtgtca aaataaaaaa
      841 aaggaagaga gggcttttct ccacaaaaaa gccagctcac agctgactcc ttagttaata
      901 atttgacaaa tctattatat caaaaaggag ctagttagtg agcaaagcta aggcaatttt
      961 aaaagactta cgcaatttag atttatatat cgctagttta atcagacgtc gagataagat
     1021 tgaggcttcg ttgctttcta gccctaaatg gtcgtctgat aaggtgaatg gtggtataaa
     1081 acgtaagcaa gatgatgttt acgtagagtt gattgcaact gccaaagata ttgaaaagaa
     1141 gactgctgaa gctataagaa aacaaagaga gcttcaaaac ctgattgata gccttgaaaa
     1201 tacagacagt caaacgattt tgagcatggt ctatattgat aagatgacta gatggcaagt
     1261 gattgatgag ctaaattgca gcgaaagcac ctatttcaga ctgttaagag ttgcaactaa
     1321 ggaattaaat aatttgacag taaatgacag cgattgacag tgaataacag tgcatgacag
     1381 ttttaaagtg ataatatagt attatcaaga aatgagggac aggtaagaaa atacccccct
     1441 cttttaaatt tagaaaggcc catccatgtc tcagttaagg gcagataaaa aaggtaccca
     1501 ccgggtagca tttgacagaa ataaaaagaa gttactaaag gcagccactg tctgtggtat
     1561 ctgtggcaag ccagtggaca agtctcttaa gtatccacat ccattaagcg cagcaataga
     1621 tcatatagtt cctatcgcaa aaggtggtca tccatcagcg cttgagaact tacagttaac
     1681 tcactggcag tgcaacaggc agaagtctga taagttgttt gctaaccaag caagcaacga
     1741 gccaaagaca attggcaaca gaaaccttcc tcaaagtcga gactggtcat cttttgcatt
     1801 taaaaagtga ttttaggcaa atatattgat ttatactaaa agctcttaga agcgaaatgg
     1861 ggggtatctc cctacccggt cggtcggccg agcttcacgc cgtcactgta cattttttct
     1921 cacgttagga tttagaaaat tttggaggtt gaatttcatt gaaaaagaaa tgcttaattt
     1981 gcaaaaaaaa cttccaagca aaaaccaata gaactttata ttgctctgaa gaatgccgta
     2041 agaaaggcaa tcgtgagaaa caacgtaaat tgatgaaaca aaaacgggct gaacagagga
     2101 aagaaaaaaa gaaagtccta aatcctaaca cagatgtgac agaaaagcct aaaaaaatac
     2161 gtaatttagc gcagcactat aaaaaactaa aaaaggaaat tttggcaaat gaatctgaat
     2221 ttggttttac tggaataaca cttattgaag gaatagatgt acatgaagaa aactttgtag
     2281 atttagtcat gcaaaaaata aaggagcaga aatgaattat atgggtatgg gctatcttcg
     2341 taggaagtta gctcttttta aaactggagt tgataaaaga tatcgttatt atgccatgga
     2401 tgacagagac gacacacgaa gtattgtcat gccaaataat gtgcgtgaaa tgtacaggtc
     2461 tgtgttagaa tggaccgcta aaggggttga tagccttgcg gaccgtatta ttttcaggga
     2521 gtttaccaac gatgatttta atgcttggga aatttttaaa gcgaataacc ctgatatctt
     2581 ttttgataca gccatacagt cagcattaat tgcatcttgt tgctttgtgt acatcatgtc
     2641 aggagcggaa gacggcttac ctaaaatgca agttatcgaa gctagtaaag cgacggggat
     2701 acttgaccca actacatttt tattaacaga gggttatgca attttagagt ctgactcaaa
     2761 cggtaatcct acgttagagg cctatttcac agacaaagac atctggtatt atccaaaaaa
     2821 agggaaacca tataatatta aaaatccaac aggtcacccc ttgcttgtac ctatcattca
     2881 cagaccagac gcagttagac catttggtcg cagtcgcatt accaaggctg gaatgtatca
     2941 tcaaaaggca gcgaagagaa cgcttgagag agcagaggtt acggctgagt tttactcatt
     3001 cccacaaaaa tatgttttgg gaatggatcc agacgctgaa ccgatggaaa agtggcgtgc
     3061 tacggtgtca acgttactcg aaatctcaaa agacgaggat ggcgacaagc caacagttgg
     3121 gcaattcaca acagcaagca tggccccttt catggaacac ttgaaaatgt atgcttcgct
     3181 atttgctggt ggttccggtc tcactcttga tgaccttggt tttccatctg acaacccatc
     3241 gtctgttgag tcaataaaag cggcacatga gaatttgaga gcagcaggac gcaaagctca
     3301 acgttctttt tcttctggat ttctaaatgt ggcgtatatt gctgtttgtt taagagatga
     3361 atttccttat cttcgtaatc aattcatgga tacagtaatt aaatgggagc ctctctttga
     3421 agctgatgca aatatgctaa ctttagtagg ggatggagct atcaaactta atcaagctat
     3481 ccctggtttc atggatgcag atgttatccg tgatttaacg ggagtaaaag gggctgataa
     3541 acctatacct gctatcacgg aggtaacaac tgatggttga tgatgtctta cctaagctac
     3601 taaaatctgt tcgacaagat tttgaaaagt attttggcga aagtgatgtt gtaaccaagg
     3661 cttttgcaga attgcaagct aaaaaagtga cctataaaac agtcaatgag tttgctattg
     3721 aagtcggaag acttttatct ttggctctga caggttctgt tagctcggat aaattaccag
     3781 acggtaaaat gtattacaat atcgctaagc gtctcttaga tgagactatg gggcggaatt
     3841 acaaattgat ttcaggttat gctggtgatg ttcagcggat tttaaatgag aatgctcaga
     3901 ttggtctaaa ggtgcaacgt ccaccgctaa atcgagacaa gattaacagg atggtaaatc
     3961 gtttggatag cgagaataca tttgatgatg taaaatggct gtttggtgaa ccgattgtta
     4021 atttttcgca gtccattgtg gatgatacca tcaaggcaaa tgcggattta caatataaaa
     4081 caggtatgac gccacaggtt gtcagaacag aaagtggcaa ctgttgtgaa tggtgtcgtg
     4141 aggttgttgg cacttatagt tatccaaaag tccctaagga cgtatggaga agacatcagc
     4201 ggtgtcgatg tacgcttgac tatgacccga agaatggaaa agttcagagt gcttggagta
     4261 aaatctggcg aaagaaagaa aaaactcaag aatctataga aagggttgaa aaatttaagg
     4321 aaagtgctct agtagaatct atcaaaaatg atatcgctaa gttagatatg acaaaggttg
     4381 gtccgagtga tataattgat atagggaaac gtatcaatta tcactttaga gtttcagaac
     4441 atataggaga taaagagaaa ttaaaagaaa ttttctcaaa ttttcgtgaa atcggtggag
     4501 aaatacctaa aaatacttgg gcaaaaggtt catctaaact tgttaaagac cagctacaag
     4561 aggcttttca aaattatcca actgagtggg cagctgttcc ggacggtatt ggtaaaaaac
     4621 taaaagctat aaaaaggaag cgcggttact tcgatggata tgatgaagat ttagttattg
     4681 ctacaaatgg aacaagaaaa acaacacctt accatgagat aggacatatg attgaactgg
     4741 ttaatcctga tttagtaaga ttagagaaag cctgggtaga taaaagaact gctaatgaag
     4801 ctgaggttcg cttgaaagat atttttccaa gttcaaatta tggtattggg gaagttacta
     4861 agaaagatga ctttatatca ccatatattg gtaaatacta cagcgatgca gctgaagttt
     4921 tcactatggg attacaaggt atttttgttc ctgaagaacg atttgctaag tcctttgaca
     4981 aaaaaacatg gaaatatgac tacaagacaa tcaatgacga ccctgaattt ttgaatttta
     5041 ttattggatt atttgtgaaa gtgtgataaa tatggaacca aaattacatc ggcaactgcg
     5101 tcaaaaatat gacgacgctg aaaaacaata tcttgaaaag tttggagaag actcgcttga
     5161 tagagtattt ttttgggagc cagacgttta ctttgatgag tggaaaaagg ttctaccaga
     5221 tgcaacactg gaattaaaca aagctattaa tagcggggtg gcgattggtc cagatccaga
     5281 aaacgcaata tattaagcac ctagagcaat ctggtgcttt tcttatgccc aaaaaggaga
     5341 aaaatatgaa taaaatatca ttaaatgtcg aaatgacttg ggaaaacaaa gacgaatttc
     5401 aacaaatcat gaataaagtc aatgaaacaa aagaagctta cgaaaaagcc ttagaagctg
     5461 cggaaaattt tgtccctaaa atgtcgtgtg caacaaagtt aaataaagga gaaggcgatg
     5521 aataagcgaa tcaaaaagaa acgtaaactc gaacgggcta ttgtgatgct ggttgcggaa
     5581 aatgctatgc aagcagaagc aattaaaaat caaaacaaag aaatcatgga gctaaaatca
     5641 atcgttcaac gaaacgctct ggcaacaaac gaagagtttg cgtctgttaa agctgctact
     5701 ttagataacc aatcagctat tgcagatatt gcaattgacg ttaactatat taagaaaaat
     5761 tacaagcgaa aatggggaaa ataaatttta aacgaattcg acccctttag aaatcaaagt
     5821 cgtagcaata cggcttttta ttgtgccctg tcgcatggct aaaaactagg cagtacgatt
     5881 gaaaggaata agtatggtta ctaagacgaa aacaaagctt ggcaatcagc gacctactca
     5941 atcggtaaat ttacattttg ctaaatctct agcgcatgaa gctattaatt actacaaaaa
     6001 aacagggcta agctgctatc catggcaagt aaatatgctt atcccaatta tggccataga
     6061 tgaaaatggt ctgtgggttc atcaaaagta tgggtatgct atcccacggc gtaacggtaa
     6121 gacggaagta gtctatattg ttgagctgtg ggctttgcat aaaggtttaa aaatcttgca
     6181 tacagctcat cgaattagca catctcatgc atcattcgaa aaggtaaaaa aataccttga
     6241 gatgtcaggt tatgttgatg gagaagactt tatatcaaat aaagccaagg gtcaagagcg
     6301 tatagagttc aaagccagcg gcgctgttat ccagttccga actaggacat caaacggtgg
     6361 acttggtgag ggatttgact tacttatcat tgacgaggca caagaataca catctgagca
     6421 agaatcagca ttgaagtaca cagttactga tagtgataat ccaatgacta ttatgtgtgg
     6481 aacgccgcca acgatggtat ctactggtac agtatttgaa gcatatcgga aagattgctt
     6541 aaaaggcaat aagcgttatt ctggttgggc tgaatggtca gttcctgaga tggttaagat
     6601 taacgatgta tcttcctggt atatttccaa cccatctatg ggattccacc tcaacgagag
     6661 gaaaatcgaa gctgaattag gtgaagatga gattgatcac aacatccaac gcttaggtta
     6721 ttggccatcc tttaaccaaa aatcagttat atccgaaaaa gaatgggcaa aactcaaagt
     6781 tgagcaagtg ccagaactca aaagcaagct ttttgtcggt atcaagtttg gtcaagatgg
     6841 caacaacgta tcactatcaa ttgcagcaag aacatcagaa aataaggtat ttgttgagac
     6901 tattgactgt ttatcggtca gaaatggaac tcaatggatt attaattttt tgaaatcggc
     6961 tgatatcgct aaggttgtca ttgatggtgc aagtggtcaa gaattacttg ctcaggagat
     7021 gaaagatcaa ggtctaaaga aaccagaatt gcctaaagtt gctgaaatta tcacagctaa
     7081 catgatgtgg gagcagggga tcatgcagga aaccatttgt catagtgatc agccatcttt
     7141 gacagcagta gtcacaaact gtgaaaagag gcaaattggc tctaatggtg gttttgggta
     7201 taaatcgctt tatgatgata gagacattag cttaatggac agtgcattgc ttgcgcactg
     7261 gatttgttac acaacgaagc caaaaagaaa gcaaagaacc agctgttaaa aaacgacatc
     7321 cgaaagggtg tttttttact gctaaaaaat ctaccgaact gccgggaaag caggagaaag
     7381 gacgttaata tgtcagaatt taaagttatt gaaacacaag aagagttgga cacgattgtg
     7441 aaagctcgca ttgctcgaga acgtgagaaa tatcaagatt acgaccaact gaaaactcgt
     7501 gttgaagaac tagaaaccga aaacagcagc ttacaaactg ctttgaatga tgctaaatca
     7561 aacactgata gctatacgga agagattagc accctgaaga atcaaattgc cgattatgag
     7621 gcggcaaatt tacggacaaa ggtagcgtta cagtatggct taccgattga tttagctgat
     7681 cgtttgcaag gagatgatga agatggactc aaagtagatg cagaacgctt agcatccttt
     7741 attaagccat cccaaccaca accgccagca aaatcaaacg aaccaaatat cgatagtaat
     7801 gcagacgcaa attacagagc gttagtgcaa ggattaagta cagaagatta gaagattaat
     7861 taaaggagaa aaaatatggg aacagaaaca tcaaaagcga gcttatttga caaacattta
     7921 gtatcagatc ttatcaataa agttaagggg catagctcac tagctaaact atctagccaa
     7981 aaacctattc cgtttaacgg atctaaagaa tttacgttta cattagattc tgatattgat
     8041 gtggttgctg aaaacggtaa aaaaacacac ggtggcttat cgctagagcc tgttactatc
     8101 gtaccaatca aggttgagta tggtgctcgt ctttctgatg aatttttata tgcaacagaa
     8161 gaggaaaaga ttgatatttt gaaagctttt aacgaagggt ttgcgaaaaa actcgctcgt
     8221 ggtattgacc taatggcgat gcatggtatc aatccacgta caaaaaaagc gtctgacgtt
     8281 atcggcacga atcactttga tagtaaagtg acgcaagtgg ttaaatttac agagagcgaa
     8341 gacgctgatg caaatatcga agcagctgtt aatctaattc aggggtctga aggtgtagtg
     8401 acagggcttg cgatggatac agagttttca acagcactgg cgaaagttac caatggggag
     8461 atggggccta aaatgtaccc tgaacttgct tggggagcga atccagatag catcaatggc
     8521 ttgaaatcgt ccgtcaatac tactgttggt gctggagctg atgaagcaga atccaaagat
     8581 ttagtaatta ttggcgattt tgaaagcatg tttaagtggg gttatgcaaa acaaattcca
     8641 atggaaatca ttaaatacgg tgatcctgat aattcgggga aagaccttaa agggtataac
     8701 caaatttact tacgtgctga ggcgtatatc ggctggggta ttttggacgc taagagcttt
     8761 gctcgtgtca ctaaaggaga agtataatgt tatacgttaa cagtaagact ggagctagtt
     8821 tttatagctc cgtccctgtt tgtggtggag attggacttt ggttgaacag cagacaggcg
     8881 aaaaagcaaa aacagtagca gaaattaaac gtcagttaga tgctgctggg ataaaatata
     8941 gctctaaagc taagaaacct gaattagagg cactcttgcc tggttaggag gtaaaagtgg
     9001 gcaatttcgc aacaacagat gacgtcattt tgttatggcg tcccttatct gttgacgaat
     9061 tgaaacgtgc aaatgcactc ttgaaagtcg tatcagatac attaagaatg gaagctgaca
     9121 aagttggcaa agacttagat aaaacgatgg ttgataagcc ttattttgtt aatgttatta
     9181 aatcggttac ggttgacatt gtagcgagaa cgctgatgac atctactcga ggcgaaccaa
     9241 tggcccaaga gagccaatca gctttaggat acacatggtc aggcacttat ttagttccag
     9301 gcggcggtct ttttattaag gacagtgagt tgaagcgtct tggactaaaa aaacaacgat
     9361 atggaggaat tgaactttat ggcgaaattg aaagggataa cagttgcttt agccgataag
     9421 tcgattagcg gaaaagaccc ttttggaaat cctgtaacag ttgattttga tatcaaaatt
     9481 gagaatgtgc ttgttgcacc agcaactacc gaagatatca ctaatcagtt atctttgacc
     9541 ggaaaaaagg ttgaatatgt cttggctata ccaaaaggag acgaacacga ttgggaaaat
     9601 aaggaagtta gatttttcgg caaaaaatgg cgcacagtag gaattccact agaaggtatt
     9661 gaagagctta taccactaga ctggaataag aaagttatgg tggaaagata tgagtaagtt
     9721 taaattcaag cttaatagag ctggtgttgc cgaattgatg aaatcatcag aaatgcagca
     9781 ggtattaacc actaaggcca cagccatcag agaacgttgt ggtgatggtt atgtccaaga
     9841 tatccatgtt gggaaaaata gggctaatgc tatggtcagt actaaaacca taaaggccaa
     9901 gaaagataac tcaaaaaata acacactgtt gaaggcggtg cgatgattga ttgaagtaat
     9961 tatcaaaaaa tatttagacg agcacttaga tgtgccgtct ttttttgaac atcaagaaga
    10021 tgaacctgca cgattcatca tcttagaaaa gactagtggg gctaagcaaa atcatttgct
    10081 aagttccacg tttgcttttc aaagttatgc cgaatcgttg tatgaggcgg ctttacttaa
    10141 tgacaaagta aagcaagtaa ttgagcagct tgatgtcttg ccacaagttt ctggtgtaca
    10201 tcttaacgct gactacaatt ttacagatac agcaactaag cgctatcgtt atcaagctgt
    10261 atttgatatt aatcattatt aaaggagata ttgatgaata agaatgatac taaaaatgta
    10321 acatctgcaa agcccaagac cggtggggcg atttattcgg caccgcttgg tactgaattg
    10381 cccaaggatg caaaatcaga attaaatact aaatttaaga atttgggtta tgtatccgag
    10441 gatggtgtgg tcaatgaaga tacacgttca tccgaaaata ttaaagcgtg gggtggagat
    10501 attgtcgggg ctgtacagac agaaaaagag gataaattta cttataagct gattgagtca
    10561 ctaaatgtag aagtcttaaa agaagtttat ggcgctgtca atgttactgg agatttaagt
    10621 gggggaatcc agattaaatc aaattcaaaa gagttagaag ctcacgtaat tgttgttgac
    10681 atgatcatga atggcggcat tcttaaacga attgtcttac caaatgcaaa agtcgatgag
    10741 gtaggtgaaa ttaagtatgt tgacggcgaa gtcgttggtt atgaaacaac actaaaatgt
    10801 ttcccggaca aggatggtga tacacaccgt gagtatattg taaaacctgg agaagctaat
    10861 aaaaaagaaa acagctttga aatgtaaagg ggagtaaatg gaaatcttaa aaggaaaaac
    10921 aacatcagga tttgaatacg aaattcctaa aaaacgatta aaaaactttg aacttgttga
    10981 agctattgca gaagaggaaa ctgatccaac agcggtagtt aaaatcgtta atttgttact
    11041 tggtgatgct gctaagtctc taaaagaaca tgtacgagat gcagaaggta tcgtagacgt
    11101 tgaagctatc ggagtagaaa tcaaagaaat ttttgaaagt caaaaagatt taaaaaacta
    11161 gcaatcctcg ctcagatgat agcaaaagat gatgatgcat tgacttgtga tttagctgaa
    11221 acatacggca tatatgatta cagacagcta cctgcttatc aggtggctgt ttttgctgtc
    11281 ggtttgagat ctaactctag gataaaaatg gcattatctg gagagactga ggctttggat
    11341 actgttttgt tagctggtat ttatgataat actaatttgc tgttttggtc taaaactaag
    11401 gatggtcaat ctggtcaaaa caaacctaaa tccgtggtgg aagctatatc tggatctaaa
    11461 tcacaaaaag ctaatgatgt catttctttt gtgtctggcg aggattttga aaatgcacgt
    11521 aaacaattac taggaggtga tggctaatgg caacagaact tggtcaagcg tatgtgcaaa
    11581 ttatgccatc cgctcgtgga ataagtggag caatctcgaa gcaacttgat cccgaagcaa
    11641 ggtcggctgg attgagcgct ggttcgctca ttggtggtaa tctcgttaaa atgattggtg
    11701 gtgccattgc agctgctgga atcggtaaga tgatttcgtc tgccttgtcc gctggtgctg
    11761 atttgcagca atcttttggt ggtattgaca cattgtataa gggcgctgag actgctgtca
    11821 aagggtttgc taaagaggca tacaaagctg gaatatcagc aaatacttat gcagagcaag
    11881 cagtttcaat gggtgcatct ctaaagcaat cacttggagg tgatgctgtc gcggctgcca
    11941 aggctgctaa catggcaatc atggatatgg ccgacaactc ggctaagatg ggtactgata
    12001 tcacatcaat ccaaatggct taccagggat ttgctaagca aaactataca atgcttgata
    12061 acctaagact tgggtacggc ggcacaaaag aagagatgaa gcgtctttta tcagacgctg
    12121 aaaagttacc tgccgctatg ggcaagaagt ttgatttgag taattatgct gatgtggttg
    12181 aggctataca cttggtacag gataacatgg gtatcgctgg agttgctgct gaagaagcaa
    12241 aaactacatt ttcaggctca ctagctgcta tgaagtcctc ttttacaaat gtaatggcag
    12301 gtttatcact aggagatgat atcagaccgg ctttacgagg actggctgag acaacttcta
    12361 atttcttatt tggtaacttt attccgatgg tggcaaatat ctttaaagga ttaccatcgg
    12421 caattggtac ttttattgga gccgcagctc ctattatcac aagtcaattc caaggtctaa
    12481 tgagtagcct tggaattagt attgatttaa gtcctattac tgctaaattt gcacagattg
    12541 gccaaaattt acaacctgtt tttaacggtt taaaaacggc ttttagtcag ttgccatcat
    12601 tttttactag cattggtagt gcagttgcac cagtaataga cactattatt agcggattag
    12661 ccagattaga tttcagtggt tttgaggctt taatttcagc aattttacca gccctacagg
    12721 caggtttttc taacttcgct gcgattgttg gaccagctat ctcaggagtt gttgactcgt
    12781 ttgttggcat gtggaatgca gcacaacctt taatttcgat actaagtgat gccttgatgc
    12841 cagtatttca aattttaggg tctttcttag gtggtgttgt aaaaggtgcg cttatgggag
    12901 ttagctttgc ctttgatgca gttaaagtgg ctatacaact agtcacacca attattgact
    12961 tgctggttca aggtcttaat tttgtacaac ctgttctcag tgtcattgca gaatggattg
    13021 gagttgctat cggtatgttt ggtaatttag gcacagccgg ccaaggcttg agcgctttta
    13081 ttaagagcgc ttggactaac attcagactg caatttcaac tgctggaaca atcatatcta
    13141 cggttattga ctacataaaa ttagcgttca gtggtgccgg ttctgcagtt ggcgtcctaa
    13201 aaaacatttt ctcacttgct tggatggcaa tgggagacgc aataaatgtg gctaagggta
    13261 tcataagctc tgttataaat ggcataaaat cagccttcag tagttttagt agcttagtgt
    13321 ctagtgttgg ttcagcagta aatggagtta tcgattcaat ctcaagcaca attagaggtt
    13381 tggcaaacat tgatatttct ggagctggtg ccgcaattat gaatggtttc ttaaacggtt
    13441 tgaaatcagc ttggggagcc gtcaaaagtt ttgtgagcgg tatcgccaac tggattgcag
    13501 aacataaagg acctatctct tatgatagag ttctactaaa acctgctggt aaagcaatta
    13561 tgggtggact taatacaagc ttgattgacg gctttaaaga ggttaaatca aatgtctctg
    13621 gcatggctga cgaccttgca agcaccatga caggtaaaag tctatctctc ggtatcgatg
    13681 ctaaaccaag cgtcacagct gatgacttac tatcaagcaa tattagtact aaaactacag
    13741 tcggttctgc tacaagtgac ttgtcattat tctttgttaa ggtgcttgct ctgttgcaag
    13801 atatccttga taaaaatacg gatgtctatc tagacaaaga aaaagtcagc gctattttat
    13861 acgaagaatt tgccaaaatt atggctagag aggggattgt atgataccta aagttattat
    13921 tgatgatttt gacacatctt caatccctaa ttgtgttttg accggttacg atgtggggga
    13981 tattctatcc cctagttttg tcgaaaatga agcttatggc atgaatggaa ctagtaggga
    14041 attggagtca tataatgaat ctaaaccaac cataatgtgg catttgagta cttttgatga
    14101 tgcagttaat ctaattaatc atttagacgg ccttagtaaa aaaatcgaat tttggcacat
    14161 acctaactct atttattact atgattgctt atctgtcaaa atcaatgcgg taaccatgtc
    14221 atcatggcgt gtgactctca aacttgctct ttatccattt agatacgcaa aaggtgtctc
    14281 agatgtagta attgcaggca acggaaacat taacaatgca ggaaatgttt tcagcgaacc
    14341 taagatagtt gttgagggta ctggtaaagg aacgctaacc attggcaaac aggtcatgga
    14401 attaaatttg tcaggtaaag caacgattga gtgcaaacat ggccaacaat gcgtctatga
    14461 tgctgaaggt aatgtgaaaa actcaatccg aataagagga agtttttttg aaatacaacc
    14521 tggcacacaa ggtattgccg tcagtggagg cattactaga acaataatta gtccaaggtg
    14581 gaggtataag gtttgatatc gattaaagat gataataccc ctcttgtagc agcctttgaa
    14641 gatgagatta cacaggaggc caatagtgat tacaaactaa attttaagta tcctgctaaa
    14701 cacgagtatc gccctttaat aaaaaaagga ataatcttag aagctgatga tctgcatggt
    14761 tctcagcttt ttaggatttt tgaaattact aagcggcatg gctatattaa cgtttacgct
    14821 aatcaggtcg ctgatgacaa tacaatgcac gactttgtaa agcctaaagt taccactcaa
    14881 caagcttttg gactagctca gcaggtcaaa gagcttgatt tacagctaaa agaccctaag
    14941 tcagatttgt ggggcaaaat caagttcaat aataaggcaa tgctagtcga gtacgccaac
    15001 aaagagatgt caagtgccat tgcgcaatca gctgagcaga tattgttaca agtcaagtct
    15061 attgatgatg aacgatattc caaatttgag caaactctga atggtatcaa acaaactgtc
    15121 aaaagtgagt cagttgaatc cgcacgtact cagctagcat caatgtttga tagtcgtatt
    15181 agtggacttg atggcaaata cagtcgtttg agccaaacaa ttgatagtct tagcagtcgt
    15241 cttgatgatg gtgttggtaa ctactcaacg ctatctcaaa aggtaagtgg cattgattta
    15301 cgagttagta atgcagctaa tgatgtttct cgattgtctc agacagcaca aggattgcag
    15361 tcacaaatca caaatgcaaa ccaaaattac agcagtttgt ctcagactgt acagggacta
    15421 caaacaactg tacgtgataa tcaatcaaat gctacaagtc ggattaatca gttaagtaac
    15481 ctgatcagca caaaggtatc aaaaggtgat gttgagacaa ctattgctca gagttacgac
    15541 aagatagcct tcgcaatcag ggataaactc ccagcaagca aaatgtctgg cagtgagatt
    15601 atctcggcaa tcaatcttga taggtctggg gttaaaatca ctggaaaaaa tatcactctt
    15661 gatggtaaca gctacatcag caacgctgtc atcaaagatg ctcatattgc taacatggat
    15721 gccggtaaga ttaatactgg ttatcttaat gctaatagga ttgcaaccga ggccattact
    15781 ggtgagaaaa ttaagatgga ctatgccttt tttaataaac tcactgctaa cgagggatat
    15841 tttaggacgt tgtttgccaa agacatcttt gcaacatcag tccaatctgt aacactatca
    15901 gctagcaaaa ttactggagg tgtattagcc gctacaaatg gggcaagtca gtgggaccta
    15961 aataatgcca atatgacctt taatcgagat gccacaatta attttaatag caaaaacaat
    16021 gccttagtac gtaaagatgg cacacatact gcttttgtac attttagtaa tgccacacca
    16081 aaaggctata gaggctcagc gttatatgcc tctatcggca ttacctcatc aggagatggc
    16141 atcgacagcg cttcttccgg tcgttttgca gggctaaggt catttaggta cgctacggga
    16201 tataaccata ctgctgcagt cgaccaaacc gagctatacg gtgataatgt cttgattgca
    16261 gatgacttta gcatcaatcg aggatttaaa tttagaccac acaaaatgga aaaagtgctc
    16321 gacatgaacg acttgtatgc ggctgtagta gccttaggcc gctgttgggg gcacttggct
    16381 aacgtcggct ggaatactgc tcatagcaat tttacaagtg ctgtgagtag ggaattgaat
    16441 aactacatca ctaaaattta acaggagata atatgcaatt aactattaaa aacaaagatt
    16501 taaacacact atatcgtgta ctagacaaaa tcaaagtcac gaacatgcga gcaaaccgcg
    16561 gacgtgctaa gctactcgca aaagtagtag ataaattcaa agagtacgcc aaggatgagg
    16621 gtgaccttat tgatctgtat gctcaaaaag acaaagatgg caagtttgtc attgatgagc
    16681 acaaaaacat caagctagca gaccccgcta aactcgacga gttcaacggc ctactcaacg
    16741 agctagctga tgaagaaatt gtgattaaag ggggtgagta ctccaagcga tttattgact
    16801 ttttaaactt tttagaagag tgtgaagatg aatttacatc atctgaaatc attcttatcg
    16861 acaacatttt ggaacaattt gaagaaagta aaaaaggaga aaaaccatga gaaattggaa
    16921 agtgacagga aaatacccac aatttgacag cacaggagca gtcgcaagta cacacgtcat
    16981 tatcgctgca gaagacggcg ctgttatccc gcaacttgtt aaaaaagatt taacaggcac
    17041 aaatgataaa gacattatca cagcagtgct cgaagagttt aaaaaatctg aatacgttga
    17101 aattgcaatg ggcgaagccg tgcaaaaagt agacgacctt gaaaaaatct cacaggaaac
    17161 cgctaagact gccaaaactg ctcaaacagc tgctggacta gctaaggtgt ccgcagagcg
    17221 tacacagcga atgattaact tgcaaaccat ccacatgtta acgagcggcg gcaagattga
    17281 tcctgacatt tataaaggca tgcttgagct aatcgagcca gccaaaaaag gtgagtatca
    17341 agcctatgat gtctttacgg tggtcgacag tactaaagag gaagacggtg aagcaggcga
    17401 agggaaccta gtctttgtac acgttaatga agcatttgag tatgacaaac aaaccttaga
    17461 ggagctagag tcagaagcca aagtaacagt tatcaagtac gctgatttgg ttaaacaaga
    17521 ttagaggtgt tttatggcaa cagagttgat atttggcgtc ggtggcttta ttttagctat
    17581 cgtcacgact tacaatattt ttaatgcaaa atccatcaag catgcgacag atattacttt
    17641 gttgcaatct gaggtagagc atttaaaaat tgttacacgc caaaatgctc ggcggcttga
    17701 agagcacgct gagcaaaata aaacgttgat tacaatgaca gagcaaatta aaaatttaac
    17761 agatgatgtt aaagatttaa aagatatgat gagaggagaa atcaaatgat caatttaaaa
    17821 ttacgactac aaaacaaagt aaccttgatg gctattttgg gagctatctt tttgttagcg
    17881 caacaattag gtattaaact accatcaaac atcgcggata ttgccaacac agctgtaacg
    17941 cttttggtat tgctcggtgt tgtcacagat ccaaccacaa aaggcctgtc agacagtgag
    18001 caagcattga cttaccacga accaaaacaa taggaggagc catgcgagca atcacacgat
    18061 tagcattagt tatagcaatc gcaatactgt atgtgccgat atctgttgtt gctctgatct
    18121 tttatccatt tttagataag gaggacagat gaccttttta gataaaatta aacaaggctg
    18181 tttagatggc tggacaacgt acaaaatctt gccatccttg accgcagcgc agacaatctt
    18241 agaaagcggg tggggcaaac atgccccaca caacgctctg tttggtatta aggcagatag
    18301 ctcttggact ggtaaatcat ttgataccaa aacccaagag gaatatcaag caggtgttgt
    18361 cacggatatt gtggaccgat ttagggcgta tgatagttgg actgacagca ttattgatca
    18421 cggtaaattt ttaaacgata atccacggta tcaggctgtg attggtgaga ctgattacaa
    18481 aaaagcttgt cacgctataa aagatgcagg ttatgccaca gctagcggtt atgcagagtt
    18541 gcttatccaa ctaatcgagg aaaatgacct tcaggaatgg gatgaagagg ctattgtcag
    18601 aaaggagaag caaatgatta gttctcaatg tcgagaagtc attgaatttt ttattaactt
    18661 ggtaaatgct ggggttggcg tggataaaga tggttttgcg ggctggcaat gcacagatgt
    18721 gccttgttat gcagcaaagc actggtttgg tgttgatctt tggggaaatg cgattgactt
    18781 actagatagc gctgctgccg taggttggga agtccaccgc atgccgacag atgcaaatcc
    18841 acagactgga gcattttttg tccaatcagt gccatatcat caatttggtc acacaggagt
    18901 tgtcattgag gatagcgacg gttataccat gcgaactatc gagcaaaaca ttgatggcaa
    18961 tcctgatgct ttgtatgtcg gtgcaccagc tcgttttaat actcgtgatt ttaccggcgt
    19021 gacaggatgg ttttaccctc cttaccaagg agatattgtc acgcaaccag tcagcaccga
    19081 gccacaaacg tctgacacta tcgtagagac agcaaaaaca ggtactttta cgcttgatgt
    19141 cgcagaaatc aatatcagac gttggccaag tttaactagc gaggtagtag gtagctataa
    19201 acaaggtgat actatcagct ttgatagtga gggttacgcc aatggttact actggattag
    19261 ctacgttggc ggctcgggta tgcgaaacta cacggctatc gggataactg acaaagacgg
    19321 taacattatc agcctttggg gcaaattaaa ttaggagata aagctccttt agataagaca
    19381 aaaccgctct cttaatcgag ggcggttttt tgtgtttaag taattatttt tttaattttt
    19441 ttctttcatt ttcaatttct atttctcgtt ttattaacct atgaaggagg aatggaagta
    19501 gtgctaaaat agaacaacct gtaagaaata ttgcacttac tttgtcagaa cgattagttg
    19561 ataaaatggt cgataaatta tttgatagac tatttgtcaa aatagaagca aaatataatg
    19621 aattgaaagc cagtaaaata gtattcttcc atctatctac agttagcttt ttatattctt
    19681 cctgcaaacc atcatatgtt ttaataagtt caaaagcgga aacaattatc ccattaaaaa
    19741 aaatactcat taaaagaacg ataagttcat tgtcataatt aacaatataa attggtatca
    19801 cagctaaagc cattccaaca ataacactaa gtaacgatgc ttttttggac cttttcataa
    19861 aatcaccctt ttttttcaat ctactataca tattactcga ttcaatcatc ctcaacaaag
    19921 gccgttaaaa cagactaatt tctcaaagtc ctatttaagg gactttctaa atagacgttg
    19981 tttttttaaa aaatagcaca gatagtagcc tatactaatt tttcttcaaa atttaacttt
    20041 atacaaatta ccccaaatat taaataaata atctaacatt tgggataatg ttcacaatct
    20101 agatattttt attaagtata agtttatgtt aagccgcttc ttcaaactct tcggtttcta
    20161 aattactatc ttcttcgttt tgagttgaat ctagcatcat tcctgtttgg taatccaatt
    20221 cagctaaagg agatacgtta tctaatgtaa ctgatgttac tccaaagttg tctacacttt
    20281 ctttttcact acctaactta atttgaagta gatctccatt ttcatcaatt ccaacatact
    20341 gtagaactac ttggcgagga actaactcat ttttatgata aacaggagta actttatagt
    20401 ctagccagaa gttagggtgt agagctaacc agctatctaa tctattttca taatagagca
    20461 ttcctaaagg atttttgtca ctaaagccag tattaagata ttttgtcatt gtaactaggt
    20521 ttttaggctc gtcatttaag ccgctaaatt ggtaaccaac taaatggcca cggtccatta
    20581 accaagttgt ttttccatta gcgtcagtca atttgtaatt atgccagcca ggaggattga
    20641 atttaagtcc ttttcgttta atattaggct catcttgatc ttttagctgg atgtgtgcga
    20701 aggttggcct ttgcagattg tcaagatcgc ccaaaactaa ttggtagcta ccagtgaatg
    20761 gtaagattcc tggtgtctca gtcgccttcg ttcctaacaa aatttccgtg gtatcaggga
    20821 aatttctaat ttttctggct gccgtaacag tacttgtggt aaaagtggtg agaatagcta
    20881 ttaaaataac aactaaacct tgccaagtac gacgatttga tttagacata tccatgtcct
    20941 ccttttatta tttacag
//
LOCUS       DAUGJR010000035        20637 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUGJR010000035 DAUGJR010000000
VERSION     DAUGJR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20637
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.035"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            520..909
                     /locus_tag="VH800_001328"
     CDS             520..909
                     /locus_tag="VH800_001328"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEQ8362396.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            1003..2055
                     /locus_tag="VH800_001329"
     CDS             1003..2055
                     /locus_tag="VH800_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8362397.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2194..3726
                     /locus_tag="VH800_001330"
     CDS             2194..3726
                     /locus_tag="VH800_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362398.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGVPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVSPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3719..4783
                     /locus_tag="VH800_001331"
     CDS             3719..4783
                     /locus_tag="VH800_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362399.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4785..5741
                     /locus_tag="VH800_001332"
     CDS             4785..5741
                     /locus_tag="VH800_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362400.1"
                     /translation="MSLVTIFALLMSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5954..7672)
                     /locus_tag="VH800_001333"
     CDS             complement(5954..7672)
                     /locus_tag="VH800_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8362401.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDENKSSGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVEADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7848..8417)
                     /locus_tag="VH800_001334"
     CDS             complement(7848..8417)
                     /locus_tag="VH800_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8362402.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8475..9020)
                     /gene="coaC"
                     /locus_tag="VH800_001335"
     CDS             complement(8475..9020)
                     /gene="coaC"
                     /locus_tag="VH800_001335"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEQ8362403.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     LVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(9013..9705)
                     /gene="coaB"
                     /locus_tag="VH800_001336"
     CDS             complement(9013..9705)
                     /gene="coaB"
                     /locus_tag="VH800_001336"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEQ8362404.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKRLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9886..10737
                     /locus_tag="VH800_001337"
     CDS             9886..10737
                     /locus_tag="VH800_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEQ8362405.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10734..11933
                     /locus_tag="VH800_001338"
     CDS             10734..11933
                     /locus_tag="VH800_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEQ8362406.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11930..12928
                     /locus_tag="VH800_001339"
     CDS             11930..12928
                     /locus_tag="VH800_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEQ8362407.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEKAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12970..13302
                     /locus_tag="VH800_001340"
     CDS             12970..13302
                     /locus_tag="VH800_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEQ8362408.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13295..14107
                     /locus_tag="VH800_001341"
     CDS             13295..14107
                     /locus_tag="VH800_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEQ8362409.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFSPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTTIFNTFTSEDKALYDTYLQKENNCE"
     gene            14100..14981
                     /locus_tag="VH800_001342"
     CDS             14100..14981
                     /locus_tag="VH800_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEQ8362410.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGSRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILGTKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            15028..16047
                     /locus_tag="VH800_001343"
     CDS             15028..16047
                     /locus_tag="VH800_001343"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8362411.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            16175..17845
                     /locus_tag="VH800_001344"
     CDS             16175..17845
                     /locus_tag="VH800_001344"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8362412.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            17930..19507
                     /gene="cls"
                     /locus_tag="VH800_001345"
     CDS             17930..19507
                     /gene="cls"
                     /locus_tag="VH800_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEQ8362413.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMSSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            19847..20185
                     /locus_tag="VH800_001346"
     CDS             19847..20185
                     /locus_tag="VH800_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362414.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
BASE COUNT         6322 a         3486 c         4268 g         6561 t
ORIGIN      
        1 tgaaaaaggc tttcataatt ttaaaaaaat gttaaaatag gtgtataaca actgattacc
       61 aagagattat tatcattatc ttctaaggtg tcattgttat ggtgacaatc aaccatacgc
      121 tactaaagat aggtagcgtt cgatcacagg ttgatcaagt gattgaaaag tcaatattta
      181 taattttaca aatatctgta tcaatccatg ttgaatagtc tatgcttcta aggtgtcgac
      241 gttaatgtac tgacgggacc gttatagtct ttctttttgg agaaacgtcg gatgccagtg
      301 aactagttga agttaaagat gttaattcaa acagtgctga agagattgat atcgttttga
      361 acggtcgttt acttcaaagc aaagaaatta ccagtctatc ggagatgata taagtgctaa
      421 agttagatca cgttaattat ctatcaagtc gggtgcatat ttcgttaaag tatctacagg
      481 ggtttcaata gatgtagcta ttatgaaagg tgatgttaaa tggggactac tgatttagtt
      541 agttgtgctg tacaagctag tgagtatgct tatgtccctt actctcattt tccagtagga
      601 gcagctttaa aaacaaaaga tggaacgatc tatactggct gtaatattga aaatgttagt
      661 tttggtctga caaattgtgg agagcgaaca gctatattta aagccatatc tgatggtcat
      721 aaagaattgg ttgaaattgc tatttatgga gaaactatgc aacctgtatc tccttgtggg
      781 gcttgtcgtc aggtaatggc agaatttttt gatccttctt ctttagtcac tttaattgct
      841 aaaaatggtc aaactgttga aatgactgtt ggagatttac tcccctattc ttttacagat
      901 ttaatataat ctgctttaat ttctgttatc tagccgtctt ggctttatat ttactttcag
      961 caacttattt gctagaaatc ttttttagga gggttcatat tcatgaacaa gaaatttatt
     1021 ggtcttggtt tagcgtcagt ggctgtgctg agtttagctg cttgtggtaa tcgtggtgct
     1081 tctaaaggtg gggcatcagg aaaaactgat ttaaaagttg caatggttac cgatactggt
     1141 ggtgtagatg acaaatcatt caaccaatca gcatgggaag gcctgcaatc ttggggtaaa
     1201 gaaatgggcc ttcaaaaagg aacaggtttc gattattttc aatctacaag tgaatctgag
     1261 tatgcaacta atctcgatac agcagtttca ggagggtatc aactgattta tggtatcggc
     1321 tttgcattga aagatgctat tgctaaagca gctggagata atgaaggagt taagtttgtt
     1381 attatcgatg atattatcga aggaaaagat aatgtagcca gtgttacctt tgccgaccat
     1441 gaagctgctt atcttgcagg aattgcagct gcaaaaacaa caaaaacaaa aacagttggt
     1501 ttcgtgggcg gtatggaagg aactgtcata actcgatttg aaaaaggttt tgaagcagga
     1561 gttaagtctg ttgacgatac aatccaagtt aaagttgatt atgctggatc atttggtgac
     1621 gctgcaaaag gaaaaacaat cgcagcagct cagtatgcag caggtgctga tgttatttac
     1681 caggcagcag gaggcactgg agcaggtgta tttaatgaag caaaagctat taatgaaaaa
     1741 cgtagtgaag ctgataaagt ttgggttatt ggtgttgacc gtgatcaaaa agacgaagga
     1801 aaatacactt ctaaagatgg caaagaagca aactttgtac ttgcatcatc aatcaaagaa
     1861 gtcggtaaag ctgttcagtt aatcaacaag caagtagcag ataaaaaatt ccctggagga
     1921 aaaacaactg tctatggtct aaaagatggc ggtgttgaaa tcgcaactac aaatgtttca
     1981 aaagaagctg ttaaagctat taaagaagcg aaagcaaaaa ttaaatctgg tgacattaaa
     2041 gttcctgaaa aatagtgttt aagaacaaga agcgcgacct ttgtcggtcg ctctttttaa
     2101 actgagataa tttttatctc agtaaagttt gtgataggtg atagatcata ggctttactg
     2161 aaataaaaga ttgcattgaa aggaaatgat cctatgacac agcatgtcat tgaaatgaga
     2221 gaaatcacga aaaaatttgg tgattttgtt gcaaatgacc acattaactt aaatgtcaga
     2281 aaaggtgaga ttcatgcctt attgggtgaa aatggggcag gtaaatcaac tttgatgaat
     2341 atgctagctg gtctcttaga gcctactagt ggagaaattg tcattaatga caagccagtt
     2401 caaattgatt cgccatctaa atcagctaag cttggtatcg gaatggtaca tcaacatttc
     2461 atgttagtag aagccttcac ggttgctgag aatattattt taggaaatga agtagtaaaa
     2521 aatgggtgct tagatcttaa ccaagcatcg aaagatatta aggtactatc cgaaaaatat
     2581 ggccttgcaa tcaatccatc agctaaagtt tctgatattt cagtaggagc acaacaacgt
     2641 gttgagattt tgaaaacctt gtatcgtggt gcagatattc ttatctttga tgagccaact
     2701 gccgttttaa cacctgcaga aattaaagaa ttgatgacta tcatgaagaa tctcgtgaaa
     2761 gaaggaaaat caattatttt aattacccat aaactggacg agattcgtgc tgtcgccgac
     2821 cgtgtcacag ttattcgtcg tggtaagagt atcgaaacag ttgatgtggc aggagcaact
     2881 tcacaagatt tagctgagat gatggtggga cgctcggttt cctttacaac tagcaaaaaa
     2941 gctgctgaac caaaagatgt ggtcttatcc atcaaaaatc ttgaagtaga tgaaaataga
     3001 ggggttccag cagttaaggg gctatctcta gatgtccgag ctggtgaaat tgtagggatt
     3061 gctggaattg acggaaatgg tcaatctgag ttaattcaag ctattacagg tttacgtaaa
     3121 gtcaaatctg gaagtattat gattaaaaac aatgaagtca ctcatttgtc ttcacgcaaa
     3181 attactgagt tatcagtggg tcacgtgcca gaagatcgtc atcgagatgg tttgatacta
     3241 gatctttctt tagctgaaaa tacagcctta caaacctatt acaaacaacc tctaagtcaa
     3301 aatggaatct taaattatac taaaattaat gactatgctc gtcaattaat gaaagaattt
     3361 gatgttcgcg gagccaatga gctagtacca gctagaggat tttctggtgg taaccaacaa
     3421 aaggccatta ttgctcgtga agtggaccgt gatccagatt tacttattgt tagccaacca
     3481 acacgtggtc ttgatgtagg agctattgaa tatatccata agcgtttgat taaagaacgt
     3541 gataaaggta aagctgtcct cgttgttagt tttgaacttg atgaaatatt gaatttatct
     3601 gatcgaattg ctgttattca tgatggtaaa attcaaggta tcgtatcgcc agaaaatacc
     3661 aataaacaag aattgggtat tttaatggca ggtggttcaa ttcataagga ggaaggtcat
     3721 gtctaaaaat gcgcaaaaaa ttgctgtacc attgatttct gtcttgctag gatttttact
     3781 tggcgctatt attatggtta tctttggtta tgatcctatc tgggggtatg aaggtttatt
     3841 ccaaattgcc tttggtagtg ttaaaaatat tggagaaata ttccgttcaa tggggccatt
     3901 gattttaata gcgcttggct ttactgttgc tagccgtgca ggcttcttta acgttggttt
     3961 gtctggacag gctttagctg gatggatttc agcaggttgg tttgcactct taaatccaga
     4021 tatgcctcgt ccattattga ttcttatgac agctcttatc ggaatgattg ctggtggtat
     4081 tgctggagct attccaggga tacttcgtgc ttatcttggt acaagtgaag ttatcgttac
     4141 gattatgatg aactacatca ttttatatgt cggaaatgct attgttcaac gtggttatcc
     4201 tgagagtgtc aaacaaagta ttgattcaac tattcaagtt agtgataatg ctagttatca
     4261 aacgcattgg ttatcagccc taactaataa ctctcgtatt aatattggta ttttctttgc
     4321 cattattgcc attgccctaa tctggttctt gcttaacaaa actactttag gttttgagat
     4381 tcgttcagtt ggtctcaacc cacatgcttc agaatacgca gggatgtcat caaaacgtac
     4441 tatcatttta tcaatgatta tctctggagc tcttgcaggt cttggaggag tagttgaagg
     4501 tctaggaacc tttgaaaatg tttttgtaca aggatcttct ttagcagttg gttttgacgg
     4561 tatggcagtt agcttattag cagcaaattc accgcttgga atatttttct catcattcct
     4621 atttggtgtc ttaaatattg gtgctccagg aatgaatatt gcaggcattc caccagaact
     4681 tgttaaagta gtaactgcat caatcatttt ctttgttggt tcacattacc tcattgaacg
     4741 ttacattatt cgccctaaaa aattagtgaa aggtggtaaa taagatgagt ttagtaacaa
     4801 tttttgcctt attgatgtca tctatgctta tttatgcaac accactcatt ttcacaagta
     4861 ttggaggaac tttctcagag cgctcaggcg ttgttaatgt tggtttagaa ggtatcatgg
     4921 tcatgggagc gttctctggg attgttttca acttagagtt tgctgaaaca tttggaaaag
     4981 caacgccttg gatagccgtt ttagtcggtg gtattgttgg tttgattttt tctttgattc
     5041 acgctgtagc aaccatcaac tttcgagctg accacattgt cagtggtaca gtgttgaact
     5101 tgttagcacc ttcttttgct gtcttcttgg ttaaagctat gtacggtaag ggacaaacag
     5161 acaacattca acaatctttt gggaagtttg atttcccagg tttatcacaa attcctgtga
     5221 ttggtgatat tttctttaaa aatactagcc ttattggtta cttcgccatt gctttttcgt
     5281 tctttgcttg gtttttgctt tataaaacca ggtttggtct gcgtttacga tcagttgggg
     5341 aacaccctca ggcagctgac acacttggta ttaacgtcta tttgatgaaa tactatggtg
     5401 tgatgatctc aggttttctt ggtggaatag gtggagctgt ttatgctcag tcaatctccg
     5461 ttaactttgc tgtaacaact atcttaggtc ctggatttat tgctttggca gctatgatct
     5521 ttggtaaatg gaatccagtt ggcgccatgc tatctagtct tttctttggc ttatcgcaaa
     5581 gtttagccgt tattggtgct caattaccat tactagaaaa gattccaacg gtttacttac
     5641 agattgcacc ttatatggta acgattatta ttttagctgc tttctttggt caagcagttg
     5701 caccaaaagc tgatggaatc aactatatta aatctaaata acgttatatt agtaagcctc
     5761 ttagtgaggt ttaacagcac tcctaaagca agatagttag gtctagcttt aagggtgctt
     5821 ttttgggact taccgcaagt ttggattgcc agtcaccatc acaatagaag caagaataga
     5881 ctaaaaagaa ctaagtcagc ggcttagttc tttttgcttg tcttttgttt ttactgatag
     5941 ctcttaagtt gttttagcca acaaaggtat tgatttctgt ttcaatgtta gcaatttttt
     6001 cttgagcgat gtcaagagta tcacctattg tggcaatata gaacttgatt tttggttcag
     6061 ttcctgaagg gcgaactgca atccatgaat catcagctaa cgtgtacttc aaaacattac
     6121 ttggaggagt tgttaagtta gatattgttc catcattttt agtagcggtt tgtttttgga
     6181 aatcttctaa taatacaata tcagtattgt taaattgttt tggaccattt tcacggaatt
     6241 tgtccataat cttcttaatt tcagcagctc catccacacc tgaaagtgtt actgaaatcg
     6301 ttttttcagc aaaatagcca tattctttgt aaatttcatc aataccatct gcaagtgtta
     6361 aaccacgcga acggtaataa gctgcgatct cagcaaccaa aagaactgct tgaatagcgt
     6421 ctttatcacg gacaaatggt ttaataagat atccgaagct ttcttcaaaa ccaaacatat
     6481 aggtgtggtt atgtttttct tcaaactctt gaattttctc agcgatgaat ttgaatccag
     6541 ttaaaacgtt aaacattgta gcgccataac tttcggcaat ttttgttact aattctgttg
     6601 atacgattga tttagcgaga gcagcatttt ctggaagtgt tcctgctgtt ttatgagctt
     6661 ccaggatgta tttcgcaata atcgctccaa tttgatttcc agaaaggttt ttataagaac
     6721 catctggttg gcgaatttca acgcctaggc ggtctgcatc aggatcagta gctactaaga
     6781 catctgcctc aacttctcgt ccgagttctt cagcaagagc aaaggcagct tggctttcag
     6841 ggttaggcga tttaacagta gaaaagtctg gatctgcctt agcttgtgat tcgactacaa
     6901 caacagattc aaaaccggct tgagcaaggg cacggcgtgt caacatctca ccagttccgt
     6961 ggagaggagt atagacaatt ttcatgtctt ttccaaagtt attgattaaa tcttgattga
     7021 tattaacatc tttaacctct ctaaggtatt ccatatcaac atcttcaccg ataacttgaa
     7081 taagacctga tgatttgttt tcatctaaat cagcaagttc aactgcaaat ggattttcaa
     7141 tagcgcggat aaagtctgtt agtgcatcag catcagctgg tggtagttga cctccgtctt
     7201 gtccatagac tttataacca ttgaaaggtg ctggattgtg gcttgcagta accataatac
     7261 cagcataggc atttaaatgg cgaacagcaa aagagagttc tggtgttgga cgaagagctt
     7321 caaatacgta agatttaatt ccatgctgtg ccaagacctg tgcagactca aaagcaaatt
     7381 ctggagagaa gtggcgcgaa tcataagcga tagctacacc acgtttttta gcttcctctc
     7441 ccttagtttc gattaatttt gctaatcctt cggttgcttg acggacaaca taaatattaa
     7501 tacgatttgt accagcacca atataaccac gcataccagc agtaccaaat tctaagtttg
     7561 tgtaaaaagc atcttctttt gttttttcat ccattgatag taattcttga cgaagatagt
     7621 caggaagctg ctcaaaatct aaccattttt gaaaattttc tgtgtaagtc attgaaatac
     7681 tccttcaata tttataaacg ctttcattat atcattttga agggaaaaaa acactaatta
     7741 tttgcagctg tttacaaaac tttttccata ttttcaagta gctaatgtaa gaaagttaaa
     7801 ataaccaagt ttttaaaaga gaaaaactcg gttattgtga aagctaatta cctttttagt
     7861 cttgatagtg ttggaataag tacaaaggta ataatagctg agatgatcat ctcaacaata
     7921 gcgtttgatg agatgatggc tgttagtagt gctttaatat ttccatcaaa aactgtcgcg
     7981 aaaaaaataa atatcccaga taatacaaat atagtatttg ttagagaacc aatgataccg
     8041 gatactatta aaccaaactg attaggaatc aatttatagc aataataagg ggtaatacca
     8101 atcagaatac gtgggataat agcaattatt aaagaagcga aagttccatg atcgacaaaa
     8161 ggtgaaaaga gataatttgt aggcagtaga atgatggtat ttgtaatgac acttataatc
     8221 cccattaatc ctcctaaaat agcacctatc cttgggccat ataagacaga agcaataata
     8281 actgggatat ggacaagcgt tggtttgatt ggaataggcc aaatattaaa gacaagactg
     8341 ctcacaaaat gaatgactaa catgatggca aaaaagatag caatacgaga aatatctgct
     8401 gatttacggt gattcatttt actctccaaa aaatataata cttaattcta aaaaggtgat
     8461 cagaaaaacg actgttaaag tttccaaatc gtatcaatag tagctaagat aacatcaata
     8521 tcagccaaag caccaggtcc tttatctcca caggctaata agctagattt tggaggaatt
     8581 tctgtaaacc ctattgtcga taagcgttta atattttctt gagtaatagg gttttgatac
     8641 attttggtat tcatggctgg ggctattaat tttggtgtgg tagctggtag ggcaagagca
     8701 acacttgtta caagattatc agcgaatcca tatgctagat gagcaatagt attagcagag
     8761 gcaggtgcaa caataaataa atctgtgcgt tttgctaatt cgatatggtt gataactttt
     8821 gggtcatgct catccataac atctaaatga atagcatttt ttgataacac ttgcagggtt
     8881 aatggtgtaa taaattgtgt agcagcctga gtcattatga tgtgaacatc atagccaatt
     8941 ttagttaatt gactcgtaag atctgctgct ttataggcag atatactacc agaaacagct
     9001 aaggtaatat gtttagtcat gtttggtcat cctttcatat aataagtcag caattgcctc
     9061 tttggtatct gcagatgcaa cttcgttatt ggatatcaaa agagccttgt gcatacctgt
     9121 ttggatatca actaaatcat tggcgagaat ataatcagcg tgatttttag ctagacttgc
     9181 tctggctact ttaattaact cttcttgagg cacattaact agaagtttaa agccgactag
     9241 tttaatatta ggattccact gtttaacata agagataact ttgggtgttt ttttcaaaaa
     9301 aagaacctga taatcagatg cagatgagat tttcggctca ctgttatgtt cacatagaaa
     9361 acaattaagg ttatcagctt gagagacttg ttccaaatca gtcatgtaga ctggagtata
     9421 gtcagaaaca gccatactat gaattagaat gtcatggtga ggaacctgat ctttgagtgc
     9481 agccattaag tcgttaactg tttccacttc aataatcctt aggcgcttat ttggcagggg
     9541 tttagtggct gttttagtag tgactagggt aacgtcatga tgatattgta aaaatcgctc
     9601 tgtgattaat tttccaagtt gcccagttga gtgattagtg atacctcgta ctgcatctat
     9661 aggttcagtt gttccacctg atgttattat taatttcata gtcatatttt atcaaaaaag
     9721 gagctgatag taaacggaag ataatgacgc cagacattgt cttgcgtttg tattaatatg
     9781 gaatagtaat agatttctag taattaaaac gaagttctgg aaagcaagac actatagtag
     9841 ctaaaatcta aattttaagg taaaatagag caagcggttt caagtgtgaa aggaagaatt
     9901 gtgataacta ttagagattt agcgtcactg ccgatttttg tttacggtga tggaaataaa
     9961 aaagttccag gagctttgag tccttttgtg tggacagagg tgtttttaaa aactatcaat
    10021 caagaaccta atcaactgat cttacatatt tggccgatga caagaacagt tatattagga
    10081 atgttagata gacagcttcc ctactttgag ctggctaaaa cagagattgg caataatggt
    10141 tatgttcctg ttactcgtaa tattggcggt ttggctgttg tcgctgatga tgggattttg
    10201 aatttttcgc ttgttattcc agaccatttt tcggaatcta tcagtattag taatgcttat
    10261 ttaataatgg ttgatgtcat tagagagagt ttttcggatt attatcagcg tattgaatat
    10321 cacgaaatta aaaattctta ttgccctggt aattttgatc ttagtattgc aggccgcaag
    10381 tttgcaggta tcgcccagcg tcgtatcaaa aagggaattg ttgtgtctat ttacttgagc
    10441 gtttgtgggg atcaagcagc gcgtggtcaa ctcatcaagg atttttatga ggccggaaca
    10501 caaggagaag ttaccaaggt taattaccct caaattgatc cagaatgcat ggcaactctt
    10561 tcagaactcc ttgagacgcc ttttacagtg gcagaagtcc ttgaacgtct tcgattgacc
    10621 ttgcgacagc ttggcttttc cctcacggaa aaaagtccag atcaagcctt actgactaat
    10681 tttgatgctg tctatgaacg gatgcagcta gaagtcgtca gaaaggaagg caaatgaaag
    10741 aaagatttag tcctttattt gagcctttga ctttgccaaa tgggagtcaa ttggataatc
    10801 gctttgtttt gtctcctatg gtgaccaact catctacaaa agacggttat gtcacccaag
    10861 atgatgtatc ctatgctttg agacgagcag cttctgcccc tctacaaatt acaggagcgg
    10921 cctatgtgga tccttatggt caattgtttg aatatggttt tagtgttaca aaagatgccg
    10981 atatttctgg cttgaaagag ctagctcaag cgatgaaggc aaagggagct aaagctgtct
    11041 tacaactgac ccacgctggc cggtttgcta gccatgcctt gactaaatat ggctttgtct
    11101 atgggcctag ttacatgcag ttgagatctc cccaacctca tgaagtcaaa cctttaacag
    11161 gtcagcaaat agaggaattg attgcagctt acgctcaggc cactcggcgg gcaattcaag
    11221 caggctttga tggcgtggaa gtatcttcgg cgcagcgctt attgattcaa acgttctttt
    11281 cgactttttc gaacaagagg acagatagtt atggttgtca aacacttttt aatcgctcta
    11341 agttaactct agctgttttg caagctgttc aacaggtgat taaacaagaa gctcctgatg
    11401 ggtttatttt tggatttcgt gctacaccag aagaaactag gggaaatgat attggttata
    11461 gtattgacga gtttttgcag ttgatggatt gggtacttaa tgttgcaaaa cttgattatt
    11521 tagcgatagc aagttggggc cgtcatgtat ttcgaaatac tgttcgttct cctggccctt
    11581 attatggaag gcgagttaat caggtagtta gagattattt aagaaataag ctacctgtta
    11641 tggctacagg gggaatgaac acacctgaca aagctattga agcactagct catgctgatt
    11701 ttattggagt atctacacct tttgtcgtgg atccagaatt tgctcataaa atcaaagaag
    11761 ggtgtgaaga gagtattcat ttaaggattc gacctgctga tttgaaaagt ttagcgattc
    11821 ctcaggcttc tttcaaagat attgtacctt tgatggacta cggggaatca ttgcctaaag
    11881 aatcaagaac tttatttcgt agtcttactc acaattataa ggagattaaa tgaaagtcag
    11941 tattcttgat tatggggtga ttgataaaga aaaaacaccc caagaagctt tattagaaac
    12001 gcgctgctta gcacaagtag ccgacaaact tggttttcat cgtttttggg tagcagagca
    12061 tcataatatt tatgcctttg caataagcag tccagagctg ttgatgatgc atttagcaga
    12121 tcataccaaa cagattcgga taggttcagg aggtattatg cctctacatt atagtagctt
    12181 taagattgca gaatggataa tgactttaga ggccttgcac cctaatcgga ttgatttagg
    12241 tattggcaac tctttaggaa ctacgttagt tcaaagagct ctatcaagta tccattgcaa
    12301 agacagctat agtcaggttg tcacagaatt ataccagtat cttaatcctg atcatttgtc
    12361 accactaccg atttttgtta accctagggg taatacttac cctcagattt ggacgctaag
    12421 caatagtttg gagacagcag aactggctgg tcaattaggt ttaggctata cctttggtat
    12481 tttcccctat ataccaaaag atcctataac agaagctaaa agagtatcgg cacattatag
    12541 aaaggctttt aggccttcaa agctattaaa aatccccaag ttaatattag cagtttttat
    12601 tgtcctttct gataccgacg agaaagcaga agctttggct aaaccgttgg acatttggat
    12661 gcttggtcag caagatttta atgaatttaa gacctaccct gatgttgagg aggctagaaa
    12721 ctatcactta acagagaaac aaagagaagc cattgcagca aatcgtagtc gcatggttat
    12781 tggatcacct cacacagtca agaaacaatt ggataggctg atagaagctt gtcaagctga
    12841 cgaattatta gccatcccct tagttcctga atttgccaat agacaacgaa ccttagagct
    12901 gctagcagac ttatacgtga ccatttaacc ttaccaaaaa caattcccta aactgaaagg
    12961 aaagaaacaa tgaaaaaaat tgcaaattac ttattaattg agaaaacaga tgaccgctat
    13021 accattagca tgacaccaga attacaagac gatattggta ctattggtta cgctgaattt
    13081 acggataacg accaccttgc cgttgatgac attatcttaa atctagaggc ttctaagact
    13141 gtcatgtctg tcttgtcacc attggctggg gcagttgttg agcgcaatga ggcagccaca
    13201 ctaacaccaa cccttttgaa ttcagaaaaa gctgaggaaa attggattgt tgtgctaaca
    13261 gatgttgatc aagcagcttt tgatgcccta gaagatgcct agttcatttg atttattagg
    13321 ggaaatgatt ggtctgttgc aaacagagca gcttactagt tcttgggcct gtcccttgcc
    13381 taatgcttta acaaagcgac aagacttgtg gcgggcgctc attaaccagc gccctgcttt
    13441 gcccttatca aaagattact tgaatctgga agatgcttat ctagatgatt ggcgtgcttc
    13501 ttttgttcct gtatcagtca aggattgcca aaaaactaat tataccagtc tttttcttta
    13561 ccatggggat attaggtatc ttgctgtgga tgctattgtc aacgctgcta atagtgagtt
    13621 attgggatgt tttagtccta accatggctg tattgataat gcgattcata cgtttgccgg
    13681 aagtcgttta cgcttagctt gtcaggcaat catgactgaa caaggccgta aggaagccat
    13741 tggacaagca aagcttacca gtgcttatca tctaccagcc tcttatatta ttcataccgt
    13801 agggccaaga attaccaaag gacaccacgt ttctccgatt cgagctgatt tgttagcacg
    13861 ttgttatcgt tctagtcttg atttggcggt taaagcagga ttgactagcc tagctttttg
    13921 ctctatttca acaggagaat ttggctttcc taaaaaagaa gccgctcaga ttgctattaa
    13981 gacagtttta aaatggcaag cagaacatcc agaatctaag accttaacta ccatttttaa
    14041 tacctttaca tcagaagaca aggccttata cgacacttat ttgcaaaagg agaataactg
    14101 tgagtaattg gacaacctat cctcagaaaa acctcaccca ggcagaacaa ctggcccaat
    14161 taatcaaaga agcagatgca cttgtagttg gtattggagc tggcatgtct gcagctgatg
    14221 gttttactta tatcgggtcg cgttttgaga cggcattccc agattttatt gctaagtatc
    14281 agtttttgga tatgctgcaa gctagccttt ttgattttga agattggcaa gaatattggg
    14341 cttttcaaag tcgctttgtc gctttgaatt atcttgatca gcccgtaggc cagtcttatc
    14401 ttgatttaaa agagattttg ggaaccaaag actatcatat tattactact aatgctgata
    14461 atgctttttg ggtggctggt tatgatcctc ataacatttt tcacattcaa ggagaatatg
    14521 gtttgtggca atgtagccag cactgccatc agcaaactta taaggacgat acggtcatcc
    14581 gtcaaatgat cgcagagcaa aaaaacatga aagtcccagg tcaactgatt cctcattgcc
    14641 ctgaatgtga ggcgcctttt gaaatcaata agcgtaatga agaaaaagga atggttgaag
    14701 atgctgactt tcatgcccaa aaagcacgtt atgaggcttt tttatcagaa cataaagagg
    14761 gtaaagtgct ttatctagaa attggtgtgg gacatacgac gcctcagttt atcaaacacc
    14821 ccttttggaa acgtgtctca gaaaatccta atgccttatt cgttaccttg aatcacaaac
    14881 attaccgcat ccctctgtca ataaggcgac aaagcctaga actgacagaa cacattgcac
    14941 aattgattag cgccacaaaa accatttacc aaaaatcgta accaaagcca atagacggtt
    15001 aattaagaga tagagaagga gactaacatg taccttattg aaccgattcg taacggtaaa
    15061 cgtatcaccg atggagctgt tgctctagcc atgcaagttt atgttcaaga aaatctattt
    15121 ttagatgatg atattttatt tccctactat tgtgatccca aagttgaaat tggaaaattc
    15181 cagaatgcag ttgtagaaac taatcaagag tatttaaaag agcatcatat ccctgttgtt
    15241 cgcagagata ctggcggtgg tgccgtttat gtagattctg gtgctgttaa tatttgctac
    15301 ttgattaatg ataatggtat ttttggtgat tttaaaagaa cctatcagcc cgctattgaa
    15361 gcccttcatc atttgggagc aacagaggtt gaaatgtctg gacggaatga cttggttatt
    15421 gatgggaaaa aggtatctgg cgctgcgatg actattgcta atggccgtgt ttatggggga
    15481 tattcccttt tgctagatgt ggactttgaa gccatggaaa aagcattaaa acctaatcgc
    15541 aaaaaaattg aatcaaaagg catcaggtca gttcgtagtc gcgttggaaa catcagagaa
    15601 catttagcac cacaatacca aggtattacg attgaagagt tcaaagattt aatggtttgc
    15661 caattgttac agattgagac gattagccaa gctaagcgtt atgatttaac ggaaaaagac
    15721 tggcaacaaa ttgatgcttt aacagagcgc aaatatcaca attgggaatg gaattatggc
    15781 aacgcgcctc aataccgtta ccatagagat ggccgtttta ccggtggaac agtagatatt
    15841 catttagata ttaaaaaagg ctatattgca gcttgtcgca tttacggaga tttttttggc
    15901 aaggcagaca ttgcagaact tgaaggtcac ttgataggaa cacgaatgga aaaagaggat
    15961 gtcttagcta ccctcaatgc aattgattta gccccttatt taggtgcgat tacagcagaa
    16021 gaattaggag atttgatatt ttcttgataa aaaagatacc tcagaccggt aaagtgtgat
    16081 taaaaacgaa caataattgt tttaattcaa ataaatgtac gtatgatatg aattgtgata
    16141 taatgacgtc attacgtaaa attgaggagt catcatgaaa tcagatatcg aaattgccca
    16201 aagtgtcgcc ttacaaccaa tcactgacat tgttaaaaag gttggaatag acggcgatga
    16261 cattgagctt tatggcaaat ataaggctaa attgtctttt gagaaaatga aagctgtcga
    16321 agctaatgag cctggaaaat taatcttggt aactgctatt aaccctactc cagcaggaga
    16381 aggaaaatca accatgtcta ttggactggc agatgcctta aatcaaatgg gaaaaaaaac
    16441 catgcttgcc ttacgtgaac cctcccttgg tcctgttatg gggattaaag gcggggcagc
    16501 aggtggtggt tatgcccaag tattgcctat ggaagacatt aatcttcact ttactggtga
    16561 catgcatgcc attacaaccg ctaataatgc attatctgct ttgattgaca atcatttgca
    16621 gcaaggaaac gatttaggaa ttgatcctcg ccgcattatt tggaagcgcg tgttggacct
    16681 taatgatcgt gctcttcgtc aggtaattgt tggcttaggt agtccagtga atggtgtgcc
    16741 acgcgaagat gggttcgata tcacagtagc ttctgaaatc atggcaattt tatgtttggc
    16801 aactgactta aaagatctaa agaaacgtct tgctgatatc gttgtggctt atacctatga
    16861 tcgtaagcct gtctatgtgc gtgacttgaa ggttgaagga gccttgacat taattctaaa
    16921 agatgctatc aagccaaact tggtgcagac tatttatgga acaccagctc ttattcatgg
    16981 ggggccattt gctaatattg ctcatggttg taattctgtc cttgctacct caacagcttt
    17041 gcgattagca gattacactg ttaccgaagc aggattcggg gccgacctag gagctgaaaa
    17101 attcctaaat atcaaagtac ctaatcttcc taaagcacca gatgctatcg ttattgttgc
    17161 aaccttgcgc gcccttaaaa tgcatggagg tgtcgccaaa tcagatttag ccgctgaaaa
    17221 ttgtgaggct gttcgcttag gatttgccaa cttaaaacgt cacgtggaaa acatgcgcca
    17281 attcaaagtt ccagttgtgg tggctatcaa tgaatttgta gcagataccg aggctgaaat
    17341 tgctacctta aaagcgcttt gtgaagagat taaggttcca gtagaattag ccagtgtttg
    17401 ggcaaatgga gctgagggag gcttagcatt agctaaaaca gtggttcgtg tgattgatca
    17461 agaagctgct gactacaaac gtctctattc agatgaggat actttggaag aaaaagtgat
    17521 caatatcgtt acccagattt atggtggcaa agctgttcaa tttggcccca aggccaaaac
    17581 acaattgaag cagttcgcag aattcggttg ggataaattg cctgtttgta tggctaagac
    17641 ccaatacagt ttttcagata acccatcctt gcttggagcg ccaaccgatt ttgacattac
    17701 cattcgtgaa tttgttccta aaacaggagc aggttttatt gttggtttaa caggtgatgt
    17761 gatgaccatg cctggtttgc ctaaagttcc agctgccatg gcaatggatg tagcagaaaa
    17821 tggcacagcc ctcggtctct tttaggaaaa attgctcgaa taattcgagc aagcgctcct
    17881 ttcttcccgc tttactgtga tataataagg taaatgagat tttggaggga tgattatcaa
    17941 aaagaaagca aaagtaaaat atttgctcca taaagggaaa catggatttt taagaggaat
    18001 ttttagtaga acaacaatca ttgtattatt aattattttg caattagttt tcttatttca
    18061 atcttatgcc tggatggagc agtaccgtgt ttggataacg attcttgaaa gtgtctttgc
    18121 tattactatt gttttatatt tagttaatag tgatatggat gctatttcaa gaatgacgtg
    18181 gttaattttg attatgattg ctccattact agggtcactg tttttaattt atacaaaatt
    18241 ggattggggt tacagagggc taaaacaaag aataaatcat cttgtagatc tgtctgcacc
    18301 ttaccttagc gatgatgacg ctatattaga ggtattaaag gatagcacat caaccacata
    18361 tcatttagta cagtacttag aaagaagtcg tggcaacttt ccgatttata ataatacaag
    18421 ggtaacttac ttcccaacag gtgaaacttt ttttgatagt ttaaaagaac agttattctt
    18481 agctaaaaag tacatttttc ttgaattttt tattattgca gaaggccaaa tgtggggaga
    18541 aatccttagt attctagaaa aaaaagtcag tgaaggtgta gaagttaggg tgttgtttga
    18601 tggcatgaac gaactatcaa cgctatcatc agattacgcc aagagattag aacaaatagg
    18661 gattaaagct aaatcatttt taccgatttc accctttatc tctacctatt acaattatcg
    18721 agatcaccga aaaattgtcg ttattgatgg ggaggtatca ttcactggag gtattaatct
    18781 agcagatgag tacattaatg aagtagagcg ttttggccac tggaaagatg ctggtttaat
    18841 gcttgagggt gaagcaacag acagcttttt aattttgttt ttacaaatgt ggtctatcac
    18901 agaaaaagaa ctgattattg atccttatct ttcagatcat tctttaaaac ttccttcaga
    18961 tggctatgtt attccctacg gtgattcccc gcttgatact gataaaatag gtaaaaatgt
    19021 ttatatagac attttaaatc atgctaaaga gtacgtttat atcatgacac cttaccttat
    19081 tttagatagc gagatggaac acgctttacg gtttgcatca gaacgtggag tagatatccg
    19141 aattattatg ccaggagtgc cagataaggg ggtaccatat gccttagcta aaacctatta
    19201 taaagctttg atgtcttctg gagtaaaaat ttatgagtat caaccagggt tcgttcattc
    19261 aaaggtattt atctctgata atacaaaagc agttgtcgga acaattaact tagactatcg
    19321 tagcctttat catcattttg aatgcgcgac ttatttatat cgtgtgtcag ttattgctga
    19381 tattgtgaat gactttaatg aagctcaaaa gcaatcacta ttgatgacat cagatcattt
    19441 gacgcaacgt ccttggtatc aaaaattgat aggattatta gtacgaacaa ttgcccctct
    19501 cttgtaattt tcgtaaaata tgttataata tctgtatgcg atgagtcgat tgtgactgca
    19561 aagtcacttt tgcgcagggg aggtcattaa ggcgggaagc cgactttgat aatctgtgtg
    19621 aaccatttta tcacaatctt atttattaag aatgcccctt ggattgagat attctcaatc
    19681 ctttttttaa ttttattatc ttagttaaaa ttcagaatgt atcagtgatt actgtgtttc
    19741 aaaataagaa agtagttttt cgggtatgag tgctatgact tgacaaatgc taataacatt
    19801 tgcataatgt aggtagagat gaaaacttat gaaaagagat gatcttatgc aaattattaa
    19861 gcgtgatggc cacgttgctg attttgatcc agataaaatt tatcaagcaa ttattaaagc
    19921 agcaaggacg gtctatgtta ttgatgacac gtggcgacaa aacttaacac atgtcactaa
    19981 aaaagtagtt attgatttag aagaagcaca tgtagaacgt cctactatca atatggtcca
    20041 atcccttgtg gagaatcgtt tgatggatgc tggatatatt accattgcag aacattacat
    20101 ttcttatcgt cttcagcgag atttagagcg caatggctat ggtgataaga ttgtggttca
    20161 cttgcgtttt gaacaaataa aataaaaacg cttctaatgg cattttagtg tctttgaggg
    20221 gataaggttt aaatacctaa cagataaaaa tctgttaggt atttttttgc tactattagg
    20281 tgtattctat attacataga acttaagcat tcaagcttta gtttaacttt ctgtttattt
    20341 tttgctacat tttgggaaac tcccctcctt tcttagttga ggtgaataaa cttttatttg
    20401 ataaattata tccttagtct taatgaaaca gtctaggata atactacttc gaagtgacag
    20461 ctagtagttt ccaattttta agtagtctaa aattatgttt ttttaatttc aaaaccatgc
    20521 tttttagaga ttttataata cttatttatc cccatttttt atattaatgg tacgaagaaa
    20581 agttagttgc tctttccaca agtatttttg attagtgagt ttaatttgct ttgtatt
//
LOCUS       DAUGJR010000036        20195 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUGJR010000036 DAUGJR010000000
VERSION     DAUGJR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20195
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.036"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            323..691
                     /locus_tag="VH800_001347"
     CDS             323..691
                     /locus_tag="VH800_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362415.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEESLGQAKEKVEGIGEATSQ
                     TIQSKMEKLTSDKTDADDEK"
     gene            complement(741..1652)
                     /locus_tag="VH800_001348"
     CDS             complement(741..1652)
                     /locus_tag="VH800_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8362416.1"
                     /translation="MKTVRIFYNPNSGKKESQLARQVKDYFCQHGFSEDSVKVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAVSIIVPTED"
     gene            complement(1769..2419)
                     /locus_tag="VH800_001349"
     CDS             complement(1769..2419)
                     /locus_tag="VH800_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEQ8362417.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(2416..2856)
                     /locus_tag="VH800_001350"
     CDS             complement(2416..2856)
                     /locus_tag="VH800_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEQ8362418.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLLQEVTQ"
     gene            3075..3923
                     /gene="ylqF"
                     /locus_tag="VH800_001351"
     CDS             3075..3923
                     /gene="ylqF"
                     /locus_tag="VH800_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEQ8362419.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFREYY
                     PNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDAD"
     gene            3913..4704
                     /locus_tag="VH800_001352"
     CDS             3913..4704
                     /locus_tag="VH800_001352"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEQ8362420.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKV
                     IQAELAEEERLEAMLSYEKALYKKGYKAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKAKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            4769..5605
                     /gene="dprA"
                     /locus_tag="VH800_001353"
     CDS             4769..5605
                     /gene="dprA"
                     /locus_tag="VH800_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEQ8362421.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            5712..7841
                     /gene="topA"
                     /locus_tag="VH800_001354"
     CDS             5712..7841
                     /gene="topA"
                     /locus_tag="VH800_001354"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEQ8362422.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGVQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEQWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(7916..8798)
                     /locus_tag="VH800_001355"
                     /pseudo
     CDS             complement(7916..8798)
                     /locus_tag="VH800_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            8811..9356
                     /locus_tag="VH800_001356"
                     /pseudo
     CDS             8811..9356
                     /locus_tag="VH800_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            9371..10363
                     /locus_tag="VH800_001357"
     CDS             9371..10363
                     /locus_tag="VH800_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEQ8362423.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIVLNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNS
                     DLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            10468..11133
                     /locus_tag="VH800_001358"
     CDS             10468..11133
                     /locus_tag="VH800_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEQ8362424.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            11126..11842
                     /locus_tag="VH800_001359"
     CDS             11126..11842
                     /locus_tag="VH800_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEQ8362425.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILLITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGVCMIMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            11993..13339
                     /gene="trmFO"
                     /locus_tag="VH800_001360"
     CDS             11993..13339
                     /gene="trmFO"
                     /locus_tag="VH800_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEQ8362426.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIEVIRGEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            13492..14898
                     /locus_tag="VH800_001361"
     CDS             13492..14898
                     /locus_tag="VH800_001361"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEQ8362427.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEASYDITLDETLLEQAA
                     NHLRQARQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            14941..15255
                     /locus_tag="VH800_001362"
     CDS             14941..15255
                     /locus_tag="VH800_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362428.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            15255..15605
                     /locus_tag="VH800_001363"
     CDS             15255..15605
                     /locus_tag="VH800_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HEQ8362429.1"
                     /translation="MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANA
                     AGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            15615..16745
                     /locus_tag="VH800_001364"
     CDS             15615..16745
                     /locus_tag="VH800_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8362430.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLASFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKIGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(16945..17829)
                     /gene="citG"
                     /locus_tag="VH800_001365"
     CDS             complement(16945..17829)
                     /gene="citG"
                     /locus_tag="VH800_001365"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEQ8362431.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFI
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(17822..18517)
                     /locus_tag="VH800_001366"
     CDS             complement(17822..18517)
                     /locus_tag="VH800_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8362432.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(18675..20078)
                     /locus_tag="VH800_001367"
     CDS             complement(18675..20078)
                     /locus_tag="VH800_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEQ8362433.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
BASE COUNT         6413 a         3751 c         4072 g         5959 t
ORIGIN      
        1 tagataattt tacttcaatt tttgattgaa aatactaaaa taagtgatgt ggtcactttg
       61 acaaccattt attggtcctt ttagataaga caattttgtg gctcttcagt tgaaaggatg
      121 tgttgttgat gttagaggaa acaatcatgt taaattaact caggcttaaa gaccaaaaaa
      181 ggagtgaagt ctattatgaa aaaaagaaat tttaaactta cagaaatgtt acaattggtt
      241 ttattagtgg ttcctgctgt aaaacttgct aaaaaaatgt ttaacgatag taaaacaccg
      301 tctaaaagaa agtaggtcta caatgactaa aaaaaatcat ggcgtttttt gggggttgtt
      361 gcttggatca gcagcagcta gcattgctta cttaagttta tcgtcttcca aaaaagatca
      421 actcttgaaa gatagtgcta aaaaaataga tgatctcaac gcttacttgc aagataaaag
      481 taagcaagtt ctggatgcag tatcggaaaa agtccaagaa tccaaagatg ctgttgaagt
      541 ttacggtggt atcgccgcag aaacagttga agaatctttg ggacaggcta aagaaaaggt
      601 agaaggaatt ggcgaagcta ctagccaaac tatccaatct aaaatggaaa aactcactag
      661 cgataagaca gatgctgatg atgaaaaata ggttttaaaa tacctttaag ataagacaaa
      721 aagtgccatt aggcactttt ttaatcttct gttggaacaa taatcgaaac ggcttttgga
      781 atgatatcta attgaatggg cagatagtca cttttatccc catcaatcct ggtacgtggt
      841 aatatcgctt gttttttagc ttgtggtagt aagctaagcg tattggcttg aaaatgactg
      901 atttcctctg ctttggaaaa atcaccctgt ttaaaatcat taatatgcca taaaaattta
      961 aagaaagaga cttttttcat ggtataaact tggaaatagc catcgtcagc ttgagcacca
     1021 ggagaaaaag aaggaaaacc agcaatggta tttgtcatcg tgattaagag aaacttcgtt
     1081 ttcaggtgaa tacgatggtt gtggctaatt aaagagatgg catagctgcg atttcgtttc
     1141 agtattcgaa tactatcttt taaaaatgct agaggaccaa agcgtcgttt ttcctcagcc
     1201 gttacgtcgg cagcaatatc agccagtaat cctaaagtta aactggaaat catgtattgc
     1261 tggttagctt tgcaaatatc aacttgcttg atttgtccag tcaagatagt atccaacgcc
     1321 tcagtaattt gtaaagggat atgcatagcc ttggcaaaat tattgactgt ccctgagggc
     1381 actaagccta ttaaacaatg agctcctcct tcatagatgc caccgatgat tttatttagt
     1441 gtcccatcgc caccaagagg gataaccaag tcaatcttgt ccttagcagc ttgttttgct
     1501 aattgaaaag cctggtcagc atctttaggg gtaataactt ttacagaatc ttcggaaaaa
     1561 ccatgttggc aaaaatagtc tttgacttgc ctagcaagtt ggctttcttt ctttccagaa
     1621 ttaggattgt aaaaaatccg aacggttttc atcaggtctc tcctttgaca gcttattact
     1681 tgctatccat tataccactt ctaagaattg atgtcttaca tcaaatcatc acattaagcc
     1741 tctcaatcag tctgagcatc tatttgtctt aaagcataaa gaaagtgata gcgataaatt
     1801 ggagggcaga ggccaataaa ataaagagat gccaaatcat gtggaagtag ggtctttttt
     1861 tggcataaaa taccgctcca atggtataag acaagccacc aaataacatg agaagaccaa
     1921 aagcaagact agttttttga atgatgactg gcaagataaa cacaacgagc cagcccataa
     1981 cgatataaag catcaaactg aatttttcat tgatacgttt ggcaaaaatt ttgtataaaa
     2041 tcccaaaaag cgtaatgccc cactgcaaaa caataatgat atagcctagc caaccagaaa
     2101 caagggataa ggcaacaggt gtataacttc ctgcgatagc aatataaatc atactgtgat
     2161 caataatgcg tagaatgtat ttgtgaaccg aaccataagc catggagtgg taaatcgtag
     2221 aggacaaaaa catcaaaaag agactgatga caaagatgga gataccaata gcggctttaa
     2281 ggtcataagt ttgataagca tagctggctg aaataggaag tagaatgagc atagcaaatg
     2341 ctccgatagc gtgtgtcacg ctgtttgcta cttcctcact aaaagataag ggtaaacttt
     2401 gtttaaaggt ttggttcatt gggtcacctc ctgtaataaa taaatagttt tgtggtaatc
     2461 tttgaccgtt tgacaggcaa cctgcacaat cggtggaatg tcctcctcaa tgggagcctt
     2521 ctgattccaa caggttacaa aagtattgta aagactttca gaatcagcct gtgcctgaag
     2581 ttcctccaat acgcgactaa tatcttgaat aggaaatacc gttttaaaca aactgatggc
     2641 aattaagcgc gctagttgtt gcttttggta ttttttcttg ataggtttag tcacataccc
     2701 atgcttgacg taattattaa tcatagatgc cgttagtgat ttattatctg acacttctga
     2761 aaaatcagtg cactggttga cataaagtaa cacttgatcc aaatataagt ctaaatcagg
     2821 gaggtccttc caataaggta atgatggaaa aatcatagtt tcgtctctct atctagtttt
     2881 gataactaga ttatatgatt aatgaaaact tattgcaagc aaaaactgta aagacttaaa
     2941 agaggaaagt agaaatggcg aagtgaagct aatcatgcta taatgttaaa gaattgattg
     3001 ggatagatgc cttctgtcgc aatcagacta ttttatcacg aagaagatga tgctacgaaa
     3061 ggaatgatac actcatggca atgattcaat ggtttcctgg gcacatgtcc aaagccagaa
     3121 gacaggttca ggaaaatgta aagcatgttg actttgtaac tattttagtg gatgcacgct
     3181 taccactttc tagtcaaaat cccatgctta caaaaattgt tggtgataaa cctaaattaa
     3241 tgattttaaa taaagctgac ttggccgatg ccactcgtac gaaagagtgg aaggcttatt
     3301 atgaaagtca aggtattaaa acattagcca tcaattccaa agaacaatca acggttaaaa
     3361 aagtaacaga agcagccaag gaactcatgg ctgataaaat tcaacgcttg cgagagcgcg
     3421 gcattcaaaa agaaaccttg cgaaccatga ttattggcat tccaaatgct ggtaaatcta
     3481 ccttgatgaa tcgcttggct ggtaagaaaa ttgctgtagt tggcaataaa cctggtgtga
     3541 ctaaaggaca acaatggttg aagtccaata aggaattgga aattctagac actcctggta
     3601 ttttatggcc aaaatttgag gacgaattgg tgggcttaaa attagcttta acaggtgcta
     3661 tcaaggacca attactacca atggatgaag tgactatctt tggcttgaat tactttaggg
     3721 aatactaccc taatcgttta accaaacgtt ttaagaatat tcctcttgag gaagaagctc
     3781 ctgaaatcat tatgaccttg acacgccaac ttggatttaa agacgattat gaccgttttt
     3841 acactttatt cgttaaggaa gttcgtgatg gtaaattagg tcaatacacc ttagatcagg
     3901 tgggagatat ggatgccgac tagtattaaa gctattaaag aaagcttaga ggccgttact
     3961 agcctcttgg accccctctt tcaagaattg gcaaccgaca ctaggtcagg cgtccaaaaa
     4021 gctctaaaaa gccgacaaaa ggttattcag gccgagttag cagaagaaga acgattagaa
     4081 gccatgcttt cttatgaaaa agctctttat aaaaaaggtt ataaagccat tgcaggtatt
     4141 gatgaggtgg gacgtggtcc cttagcaggt cccgttgtgg cagcttgtgt gattttacct
     4201 aagtattgta aaattaaagg ccttaatgat tctaaaaaaa tccctaaagc taagcatgag
     4261 accatttatc aggcagtgaa agaaaaggct ttggctatcg gtatcggtat tattgacaat
     4321 cagcttattg atgaggtcaa tatttatgaa gcaaccaaac tggccatgct agaagccatt
     4381 aaacagttgg agggccaact cacacaacca gattatctct tgattgatgc catgacattg
     4441 gatattgcta tttcgcagca gtctattctt aaaggcgatg ccaattcctt gtctattgca
     4501 gcagcatcaa ttgtagctaa ggtcaccaga gatcagatga tggctaacta tgatcgcatt
     4561 tttcctggtt atggctttgc taaaaatgca ggctatggca ccaaagaaca tttacaggga
     4621 ttaaaagctt acggcataac gcctatccat cgtaaaagtt ttgaacctgt taaatccatg
     4681 tgctgcgatt caactaatcc ttaaaaagtt ctgtttttag cagaattttt ttctttttta
     4741 cgaataaatg aagtaaggag gtaacttagt gaatcatttt gaactttata agctaaagaa
     4801 agctggactg actaataaaa acattctcaa tattcttgac taccaaaaac accaggaaaa
     4861 atcgttgtca cttcgagata tggccgttgt ttctggttgt aagcatccgt ctcactttat
     4921 agaagcctat aagcagttag atattcaaaa tttaaaaatg gaatttaaac aatttcctag
     4981 tatttctatc ttagataagc attacccaat ggcattgaaa gaaatataca atccacctgt
     5041 cctcttgttt tttcagggaa atttagacct tcttgagaaa cctaaattag ccattgtcgg
     5101 ctccagacgc tcaagcgata ccggagtaaa gtctgtccgt aaaattctta aagaactcgg
     5161 gaaccgtttt gtgattgtta gcggacttgc tcgaggtatc gacactagtg ctcatttagc
     5221 ctgccttaaa aatgggggac aaactatcgc tattattgga acaggattgg atcgctttta
     5281 ccctaaagaa aatagggagt tgcaaacttt cttagggaaa aatcatcttg tgctaacaga
     5341 atacggtcca ggagaagaag ctttatctta tcactttcca gaacggaatc gtattatcgc
     5401 aggccttagc cgaggtattc ttgtcgttga agcaaaaaat cgttcaggtt ccttgattac
     5461 ttgtcaaatt gggatagaag aaggccgaga catttttgct gtcccaggaa acattttgga
     5521 cgggaaatcc gaaggttgcc ttcagttaat taaagaggga gcaacatgcg tcacatcggg
     5581 catggatatc ctttcagagt actaaaaaag ttaaagtttc ttcctatata gcattttttt
     5641 attgacagtt tcttaaaaat gggatattat gctataagct ttaaacaaac tgttatagga
     5701 agtgtgtcga attgggaaca aaaactacaa ctaagccaaa aacgggtact aaaaagtcca
     5761 ccactaaaaa gaaatcaaca gcgaaaaaaa atctcgttat tgttgaatca cctgccaaag
     5821 ctaagactat tgaaaaatat cttggacgca gttataaagt tgttgcttcg gtaggacata
     5881 ttcgtgactt aaaaaaatcg tctatgtcta ttgattttga taataattat gagccacaat
     5941 acattaatat ccgtggtaag ggacccctta tcaattcttt aaaaaaagaa gccaaagctg
     6001 ctaaaaaagt ttatttagct agtgacccgg atcgtgaggg agaggctatt tcttggcatt
     6061 tgtcacatat cttaggactt gatcctcaag ataataaccg agtggttttt aatgaaatta
     6121 cgaaagatgc agttaaacat gcctttgtgg agcctcgtca gattgatatg gacttggtag
     6181 attctcaaca agcacgtcgt gttttggacc gtattgtggg atattccatt tcaccaattc
     6241 tttggaaaaa ggtcaaaaaa ggactttcag caggacgtgt ccagtcggtt gctttaaaac
     6301 tcatcattga ccgtgaaaat gacatcaaag catttgttcc aaaggaatac tggtctattg
     6361 atggtctttt taaaaaagga actaaaaagt ttcaagcgac tttttacggt attaatggca
     6421 aaaaaacaaa gcttgacaat aacaacgatg tcaaagaggt attagcaaag ctaacaaatg
     6481 aagattttct tgtcagcaag gttgacaaga aagagcgacg tcgtaatgct cccttacctt
     6541 acacaacatc atctcttcaa caagatgctg ctaataaaat caatttcaga acgcgtaaaa
     6601 ccatgatggt agcccaacaa ctgtatgagg ggattcattt aggagaaaat ggaactcaag
     6661 gtttaattac ctatatgcgt acggattcta ctcgtatcag tccagtagca caaaacgatg
     6721 ctgctcaatt tattatcaat cgctttggag ctaattattc aaaacatggt aatcgtgtca
     6781 aaaataccag tggtgtccaa gatgctcacg aggcgattcg tccatctagt gttaatcata
     6841 cgccagactc tattgccaaa taccttaaca aggatcagtt aaaactttat acgcttattt
     6901 ggaatcgttt tgtggctagc caaatgacag cagctgtttt tgataccgta aaggtgaact
     6961 tggagcaaaa tggcgtgatt tttgttgcca atggtagcca aatgaagttt gatggttaca
     7021 tggctgttta caatgattcc gataaaaaca aaatgttacc tgagatggca gaaggagaaa
     7081 cggttaaaaa aatatcgacc tctccagaac agcactttac gcagccacca gctcgttatt
     7141 ctgaagcaac tctaattaaa acgctagaag aaaatggtgt tggacgtcca tcaacttacg
     7201 ctccaacctt agaagtcatt caacgcagat actatgttaa attgtctgct aagcgctttg
     7261 agccaactga gcttggggaa attgtcaaca agcttattgt cgaatttttc ccagatattg
     7321 tcgatgttgc ctttactgcc gagatggaag gtaagctaga tcaagttgaa atcggagaag
     7381 aacaatggca acatgttatc gatcaattct atcaaccctt tgtcaaagaa ttgaataagg
     7441 ctgagtctga aattgaaaag attcaaatca aagatgaacc agctggcttc gactgtgatg
     7501 tttgtggtca cccaatggtc attaagttag gacgttttgg gaaattttac gcgtgtagca
     7561 acttcccaga gtgccgtaat acaaaagcca tcactaaaga aattggtgtt acttgtccgg
     7621 tttgtcataa aggacaagtt atcgagcgta aaaccaaaaa aaataggata ttttatggtt
     7681 gtgatcagta tccagattgt gagtttatct cgtgggattt acctattgga cgtgcttgcc
     7741 ctaagtcagg tgactatctt attgagaaaa aagttcgtgg tggcaaacaa gtaatgtgta
     7801 gcaatgagac ctgtgattac aaggaagaaa aaattaaata aaaaaagaat tggaactcct
     7861 tgtcttgttc caattctttt tttatttaca aaggtatttt taactacaaa aatcgctagt
     7921 tcgtttttaa aaggcttaaa aattcctcaa taactggact gaaactcgca tcatctcggt
     7981 aagcaatccc aatagggtaa aaattatttt tatcttgcaa aggaatccaa actaagttat
     8041 ctacctgatt aagactctca aaatcactcg ggaggatagt caaggtattt aaatcgtgca
     8101 aactatgaat aagaacttcc caatcattgt gtttaaagac aatatctggt tcaaaaccga
     8161 gagctcggca ttttctagga agcatttcgc ctaacatgta gtgatcgttt aaagaagcaa
     8221 tcttatagcc ttttaaatct ttaagtttta actgaggatg ttgcgccaaa gggtgctgtt
     8281 tgaggagaac gatactgacc ttatagcctt ttgtggacgt ttgtaatagc tcaatggtaa
     8341 tatcctttcg aatacttaga aaggagagga gaccaatatc gatttttcct tgggacaata
     8401 attcttataa tttgcgagaa ccatcctgta taagcgataa ttcaacattt gagtgagtag
     8461 ccataaagat tgaaatttgt ttcatgaatt gtatagcaaa cagtgatgtt aattcaacac
     8521 gaatcatctc tttttttctt gatttaattg ctgaatatcc gcaacaattt gattaaagtc
     8581 atccacaagg tctttgcctt tgtgataaaa tatctccagc ttcggttagt agtagctgtc
     8641 aatcactttg tgtaaaaagc gtcgtgttca aactaggact ctagcctttt aattgattga
     8701 gaaagagtag gttgcgttac aaacaaactt ttagcagcgt gggaatgatt ttttgtttca
     8761 gcaactgcaa taaaataggt taattgtcta atatccatag tagatccttc atgattggtc
     8821 aaggaatagc gtctctactt ggtttacaac ctattttgat gtctctcctt attgccatga
     8881 ttttctgctt ccttattgtt tctccaatta caacggtagg aattgctctt gcgattaact
     8941 tatctggtat tggttcaggt gccgcaagct ttggactttg cttagcaggt tgggctgtta
     9001 attcaaaagg aacttcactt gctcacgtct tgagatcacc gaaaatttca atggccaacg
     9061 ttttatcaaa accaaaaatc atgttgccaa tgttatgttc tgcagctgta cttggtgtta
     9121 ttggtgctat ctttaatatt caaggaacac ctgctagtgc aggctttgga attagtggtt
     9181 tgatcggacc tatcaatgcc cttaatttag ctaaaggcgg atggtgtcca gtaaatattc
     9241 tacttatcat tatcattttt gtaggggcac caattgttct caatatgatc tttaactacc
     9301 tttttatcaa ggtgcttaaa gtgattgatc caatggatta caaacttgat atctaagaaa
     9361 ggaacttttg atgaaattaa aattatataa tgttagaggc gaagaagcag tcttagcaaa
     9421 aaaatgggct gatgacaatg ggattgagat ttccttgacg gagtctccct taactcctga
     9481 aacggttaaa gaagctgaag gctttgacgg gattgccaat gcccaaattg gtcctttaga
     9541 tgatgcgatt tatcctctct taaaggaaat ggggattaaa caaatcgctc agcacagtgc
     9601 tagtgtcgat atgtataacc ttgatttggc caccgaaaat gacattatta tcacaaatgt
     9661 tcctagctat tctccagaat ccattgcaga atttacggtt actattgtcc ttaatttaat
     9721 tcgtcatgtg gagttgattc gtgaaaatgt taaaaaacaa aatttcactt ggggactccc
     9781 tatccgcggc cgtgttttag gtgatatgac agttgcgatt atcggaactg gacgtattgg
     9841 tctagctact gctaaaatct ttaaaggttt tggctgcaag gtcgttggat atgatattta
     9901 ccaaagcgat gctgccaaag ctgtcttgga ctataaggaa tctgtagaag aagcgattaa
     9961 agatgctgat cttgtttcct tacacatgcc accaactgca gagaacacac accttttcaa
    10021 ttctgattta tttaaatcat tcaaaaaagg ggctattttg atgaatatgg cgcgtggtgc
    10081 cgtcattgag acgcaagatt tactggatgc tttggatgca ggcttactga gcggagctgg
    10141 tattgacact tacgaatttg aaggacctta tatacctaag aattttgaag gtcaagaaat
    10201 tacagattca ctatttaaag ctttgattaa ccatcctaag gttatttata cacctcatgc
    10261 agcttattat actgatgaag ccgttaaaaa cctagttgaa ggtgccctta atgctacagt
    10321 agagattatc aaaactggga caacgacaac tcgtgttaac taacaactga tttgacgtcc
    10381 attataaagg aataattcta aaaattcctt tataatggac ttttttgtat tagtccgtta
    10441 taatagactg taagaaaggg gactcttatg acatatatag cgcttattgg agatattatc
    10501 cagtccaaac aattgacgga tcgttccaaa gttcaaaaaa ctttagcagc ttatttagac
    10561 gacctcaaca aaacctttgc tccttatatt atttctaaat tatccctaac gttgggagat
    10621 gaatttcaag gactttttca ggtggatact cctattttcc atctgattga tttgattaat
    10681 catcacatgg atatccctat tcgatttgga gtaggagtag gttctattct aacagacatc
    10741 aatcctgata ttagtattgg ggctgatgga cctgcttatt ggcatgctcg tgaggctatt
    10801 cgttatattc atcaaaaaaa tgattatggt aatactacat tagctcttcg gactggtcat
    10861 cacaaccagg atgatgtatt aaacagttta ctagcagctg gagatgctat taaagccaac
    10921 tggcgagcta gtcaatggga aatttttgac acgcttttag atttgggcat ttatgaggaa
    10981 tactttgatc aacaacgact aggaaagcaa ttatctctta gctctagcgc tttgtcaaaa
    11041 cgtctaaaaa gtagtcatgt taaaatttat ctgagaacac ggcagagtgc gctaaactgt
    11101 ctcaaacaaa tcaaggagga aactgatgat taatggtgtc tctcactacc tagctcaaac
    11161 ccctacactt accctgtttc tcatttgtca tgtgttatca gactaccagt tacaaagtca
    11221 gcaagtagct gatttaaaag aaaaacattt gacttattta ggttaccact tgattggagt
    11281 tagcattccc ctaatttgtt taaccctcat tatcccacaa gcatggttga tgagcctatt
    11341 ggttatgata agtcacgcgc ttattgactg gctaaagcca aagatggcta actctctaaa
    11401 atggaaaaga gagtggattt ttctgctgga tcaatgctta catatcgcta ttagttcatt
    11461 tgctgggcta aggttagcag gggtgacctt gcctaattgg cttccgatat ctattttgat
    11521 gaccgtttta tttatcctac tcattaccaa accaactaat attgtcttta aactcttttt
    11581 cagcaaatac cagcctgacc aaggagaaaa aatggacacg atcataggag cgggggctac
    11641 cataggaatt ctagagagaa ttgttattgg ggtgtgtatg atcatggggc aatttgcttc
    11701 aataggtctg gtctttaccg ctaaatctat tgctcgctat aataaaattt cggaaagtcc
    11761 agcttttgca gaatactacc taattggttc tttatttagt attctcagtg tttttatcgc
    11821 agcatggatt tgtttcttct agttgaaaag ggttcccgta gaaagagact aacgcttagt
    11881 ctctttcttt ttctttcttc ttatttctgt tataataagt caggtaacta cattagaaag
    11941 atttgtgggt ctgtcatcta agagatgtca ttcccgaaga ggtattagtg acttgtctca
    12001 atcaactgca acttatatta atgttattgg agctgggcta gctggttctg aagctgccta
    12061 tcagattgct aagcgcggta tccccgttaa attgtatgaa atgcgtggtg tcaaagcaac
    12121 accgcaacat aaaaccacta attttgccga attggtctgt tccaactcat ttcgtggtga
    12181 tagcttaacc aatgcagtcg gtcttctcaa agaagaaatg cggcgattag actccattat
    12241 tatgcgtaat ggtgaagcta accgcgtacc tgctggggga gcaatggctg ttgaccgtga
    12301 ggggtatgca gagagtgtca ctgcagagtt ggaaaatcat cctctcattg aggtcattcg
    12361 tggtgaaatt acagaaatcc ctgacgatgc tatcacggtt atcgcgacgg gaccgctgac
    12421 ttcggatgcc ctggcagaaa aaattcacgc gctaaatggt ggcgacggat tctattttta
    12481 cgatgcagca gcgcctatca ttgataaatc taccattgat atgagcaagg tttaccttaa
    12541 atctcgctac gataaaggcg aagctgctta cctcaactgc cctatgacca aagaagaatt
    12601 catggctttc catgaagctc tgacaaccgc agaagaagcc ccgctgaatg cctttgaaaa
    12661 agaaaagtat tttgaaggct gtatgccgat tgaagttatg gctaaacgtg gcattaaaac
    12721 catgctttat ggacctatga aacccgttgg attggaatat ccagatgact atacaggtcc
    12781 tcgcgatgga gaatttaaaa cgccatatgc cgtcgtgcaa ttgcgtcaag ataatgcagc
    12841 tggaagcctt tataatatcg ttggtttcca aacccatctc aaatggggtg agcaaaaacg
    12901 cgttttccaa atgattccag ggcttgaaaa tgctgagttt gtccgctacg gcgtcatgca
    12961 tcgcaattcc tatatggatt caccaaatct tttaaccgaa accttccaat ctcggagcaa
    13021 tccaaacctt ttctttgcag gtcagatgac tggagttgaa ggttatgtcg aatcagctgc
    13081 ttcaggttta gtagcaggaa tcaatgctgc tcgtttgttc aaaagagaag aagcacttat
    13141 ttttcctcag acaacagcta ttgggagttt gcctcattat gtgactcatg ccgacagtaa
    13201 gcatttccaa ccaatgaacg tcaactttgg catcatcaaa gagttagaag gcccacgcat
    13261 tcgtgacaaa aaagaacgtt atgaagctat tgctagtcgt gctttggcag atttagacac
    13321 ctgcttagcg tcgctttaac actaaaaaag agttcctttt cagttgagtt gctgaagagg
    13381 acttttttac ttgctgattt gagcgctagc tatgcaaaag aatgcacaaa aaatacatga
    13441 atagactatg gtcactagaa gcaatattat ataatgaata gtactcatta gttgattcag
    13501 tttggaggtt ttagcatgca gcagcaagtc gcaataacag aaacagtttt acgggacggt
    13561 catcaaagtt tgatggcaac gcgtttatct attgaagata tgcttcctgt ccttaccatc
    13621 ttagacaaga ttggttatta ttccctagag tgttggggag gagcaacctt tgatgcctgt
    13681 attcgttttt tgaacgaaga cccttgggaa aggctgcgca cgttaaaaaa aggcttacct
    13741 aatacccgtt tacaaatgtt attaagaggc caaaaccttt taggctaccg tcattatgca
    13801 gatgacatcg ttgacaaatt cattagttta tcagctcaaa atgggattga tgttttccgc
    13861 atttttgatg ccctaaatga cccacgaaat atccagcaag ccttaagagc tgtgaaaaag
    13921 acgggtaaag aggctcaact gtgtattgcc tatacaacta gcccagtgca cacgcttaac
    13981 tattaccttt ctttagtgaa agaattggtt gagatgggag ctgattctat ctgcatcaaa
    14041 gatatggctg gtattctaac tcccaaagcg gctaaagagt tggtatctgg tatcaaagcc
    14101 atgactaact tacctcttat tgtgcatacc catgcaacta gtggcatttc tcagatgacc
    14161 tatctagcag cagtagaagc tggtgctgat agaattgata cggctttgtc accttttagc
    14221 gaaggcactt cacaacctgc tacagaatcc atgtatttag ccttaaaaga agcaagttat
    14281 gatatcacat tagatgaaac gctactggaa caggctgcta atcaccttcg acaagcccgt
    14341 caaaagtact tagcagatgg cattctggat cccagtcttc tctttccaga cccaaggaca
    14401 ctacaatacc aagttcctgg aggcatgttg tctaatatgc tatctcagct gaaacaagcc
    14461 aatgccgaat caaaattaga agaagtttta gcagaagttc ctcgggtaag aaaagacttg
    14521 ggttatcctc ccttagtaac accgcttagc caaatggtcg ggactcaagc tgctatgaat
    14581 gtgattttag gaaaacctta ccagatggtg tctaaggaaa ttaaacaata cttggcaggc
    14641 gactatggca aaacaccagc accagtcaac gaagacttaa aacgaagtca aattggctca
    14701 gctcctgtca ccacaaatcg tcctgcagat caactaagtc ctgaattcga ggtgttaaaa
    14761 gcagaagtag cagatttagc ccaaacggac gaagatgtgc tgacttatgc cctcttccca
    14821 agcgtagcaa aaccgttttt aacaaccaaa taccaaactg atgacgtcat taaagtgact
    14881 gcctttatca aagcataata ggctatctta atcagataga aacaaaaata tggagatcaa
    14941 atgacctatt cctttattga tatcttacaa gttaccttag tatccttgtt cttagtgtta
    15001 acctgtttaa cagggattat gggattaatg atgctaagtg gtaaattatt gtcacaagaa
    15061 aaaaaaactc tctctcaaca agcttccagc attcctcaag agcaagaagc tgacaagttg
    15121 agtggagaag ctctcgaaac tcttttagcc aaagacgaat tggctagaat tgctgttatg
    15181 actagtcttg cttatgctag ccaagaagag tcaggaaaac ggtttgaagt tattgccgtg
    15241 gaaaggaaat cctaatgaaa agatatgaag tgactgtcaa tggacaggtt tatgaagtga
    15301 gtttacgtga actagttgat ggagaaactg ttgaagttag ccagccagca gcacccgcta
    15361 ctgagaaaga aatgaatgcc aacgctgctg gcggtggcat tcaggtaaag gctccaatgt
    15421 ctggaacagt cttgtctatc tttgctacag aaggaaaagc tgttaaaaaa ggagaagctg
    15481 ttctggtctt agaggccatg aaaatggaga atgaaattct agcacctgca gatggtctgg
    15541 tttcaaaaat tcatgttgtg gctaaccaaa cggtcgagtc tgaacaagtt ttgatttcat
    15601 tctaggagga aaccatgcta gacgtactca atcaaatggt ccaatcgtca ggattggctc
    15661 atctaactgt taataatctt atcatgattt gcttggccag tttcttttta taccttggta
    15721 tcaaaaagga atatgagcct taccttatgg taccaatcgc ctttgggatt ttactcgtta
    15781 atttgcctat ggcgggattg atggaccacc ctgccaatgg taatcctggt ggccttcttt
    15841 attacctata taagggaact agcctaggga tttacccacc tttaattttt ctttgtttgg
    15901 gggcatcaac tgactttggt cccttgattg ccaatcctaa aaccatttta ctaggaggcg
    15961 cagcacaagt tgggattttc ttagcctttt tccttgctat tatgttaggc atgacacctc
    16021 aagaagcggc ttctgtcggg attattggtg gtgccgatgg accaacagct atttatgtga
    16081 cgacaaagtt ggcgcctgat ttactctcta ctatcgccct agcagcttat tcttacatgg
    16141 ctctggtacc tattattcaa cctcccatca ttaaactctt gactaccaag gcggaacgcc
    16201 aagtgaaaat gactcaagca agaactgttt cacaaaaaga aaaaatcatt ttcccgatta
    16261 tggtaacaat ctttgtcagc cttttggttc caagtgctac aaccttggtt ggctgtttga
    16321 tgctgggaaa tctggtcaga gaaattaaaa ttgttcctaa aattgtagag aatctccaac
    16381 aagtggttat gttttgcatt actatcattt tagggttaac cgttggtgct aaggccaatg
    16441 gagatctctt tttatcagcc acaaccttga aaattattgc ccttggacta atcgcctttg
    16501 ctgctgggac agcagggggt gtcttgatgg ggaaggtcat gtactattta tctggtaaca
    16561 aagtgaaccc tatgatagga gcagcaggtg tttcagctgt tccgatggca gcacgagtgg
    16621 tccaaaagat cggacaagaa gaagatccaa gtaatttctt actcatgcac gccatggggc
    16681 ccaatgtagc tggcgttatt ggctcagcca ttgcctcagg tgccttgctg gccttctttg
    16741 gctaattgtg aaaaaggatt agtaaattaa tcttaataaa tcattatcag gagttggaag
    16801 caatctagct ccttttttag tagaaagctc gagtgataaa ctattccaaa ataattataa
    16861 aaaagactgt cctgattgta cggactatat cagttgactt ttatagtcta gctgaaatag
    16921 cagtgcaaaa ctaagacact cgttttaaag tagtttttct aaaaaagcaa aataaaaggt
    16981 cagagccaat aaatctgccg cgcccccagg gcttaaatgc tgattaatga ggcattgatt
    17041 gtaggaggac aaagccaatc ttaggtcagt tgttgataaa tcttgttgca ggagtagtcg
    17101 catatctgcc ttaacgcctt tccatgcttc aatccctcca cgatgaatca gatttccatc
    17161 ttcaacaata gacatcaaat aaacaagaag acgaagctga ctggtttcgg ggtcattttg
    17221 acttatcatc tgacgaaagt agggcaaggc atggtctgtt aaggtcgtga atccctcgct
    17281 tgcctcaccc cgaggtcctt tgatgccata agttacaaag agttgctccc cataagtgaa
    17341 ctctttttta gtgttcaaat gaccaaggtc tgtttgaatc aaatgtgccg tcataggttt
    17401 tactaaacga cagatagcta gagtatcttc cttgctaaaa cgccctaaat cagtcattaa
    17461 gtgaggtgtt cttgctagat aggccccagt tgcaccaaga agtaaagcca tggaaaaatt
    17521 caggccttta tgagtgttaa ttccctgagt agcacaaaac atggtttcct cggccttttg
    17581 acctagttgt ctaagacggt taaacagaag aagtggctct tcttttgcat aagcaaaacc
    17641 tgtttcgata taagcctgaa aaaaaggaga gagtgctatc atactgtcga taaaggttat
    17701 aaaggacatg tcatcatggg caccgttatc aaatcgatca actaaaccag gttttggaga
    17761 tagtgagact tcataaagca aagcttttaa ggccagttga ctaatacttg ttagaactgc
    17821 cttagtcatt ttgctcaggc ctcatttctt ttaagataaa ttcaagtgag ctattcaagt
    17881 gttcatgtgt aatcaacgta atttgctcat gatctttgtt cttcatacct cggtaaatca
    17941 tccagtgttc agatagagct cgtttacggc gttcaactga agaaatcgaa atttttctaa
    18001 agtagaccaa ataagcttgc aattctgtca caatttcttt taagcggacc atttggctat
    18061 agctgtaaat caaattgtta aaggcattaa aattatccaa aatacgattg gtgtcatcct
    18121 ctgcgataaa ggtttcacag tcttccaaca agttatgcat gactttaaaa tcttcttctg
    18181 tcattaaatg catcgcttgc actgttgcga gagtctctag agcttttcga atttcaaaaa
    18241 tttcacaggc atccttgata ctaactcctt tgacaataat gcctttttta ggaatgtgct
    18301 ctacaaggtg ttcttcagac aataatccca aagcgtagcg aataggtgtc ctgctaatat
    18361 taagcgcaat ggaaaactct ttttcattaa tgcggcttcc aacaggaatt tgtcgcaaaa
    18421 taatggtctt tttaagagcg ttataaaagg ctattttcaa agggatattt cttgataggt
    18481 caagattttg tttaacggct tcgataatag gattcatgtc atctccttaa tgctagtgtc
    18541 ctcactttat tatacttaaa tttgtgaaac attccaatag gactagatga gttctgaaaa
    18601 attaaagcca tgctcacaaa aggacatgac tttaatcatc tcataaggaa taaggtagta
    18661 gtgttatcgt tggtttattg tggaatgtaa agtggcattt gtcccatggc aataatggtt
    18721 accacaaaga taacaaagat gataagggca tatttagcag cctctttttg ccattccccc
    18781 atgtcaagac ctgtcaagcg aagaagaaga taaatgaagg caactaatgg actaagtaag
    18841 tggaaggctt gtcccatgag ggaagcaagt gccatagcca tgttactgaa accatattca
    18901 gcaccagctt ctgcaagaac aggcaagata ccatagtaaa aaccatcatt ggagataaag
    18961 aaggtaccag gtgcagaaac taaggcaata acgagacccc agaaacctgc cagttgtttt
    19021 ggaataatgg ttgcaaaact ttgtgcaaga gcgctagcca taccagaacc ttgaaaaaga
    19081 cccataaaga taccagcagc aaagacgaga ataaccactt gaaccgcatc accagcattg
    19141 tcaccaatgc gttttgattg atctttaagc actgggtaat tgaccatcaa ggcgatacaa
    19201 gttcccaccg caaaaagaag aagcggtgcc atagcaatag atttgttgaa agagccagca
    19261 actaaccaag tgattaatcc aatggttaag atagcattga aaacaaagtt tttaggacga
    19321 cgaataaaaa gggtatctgg gtcagtaatg tctgtgagtt gacgcatgtc ttcttcagac
    19381 aagtcaataa caccaagtct tgcacgttct ttacgcccca tgcttggagc aacccaacaa
    19441 atcacataaa gaagagataa aatcataccc ggtgcaagat agccaagaat ttcaggaccg
    19501 acaccaagaa cagacatcgc acgagcagta gggccacccc atggcagtaa gttcataata
    19561 gtattttgaa gaataatcaa gacacctagg ttcatgattt tcatgtccaa ttttttatag
    19621 ataggtaaga aagcagagca acaaattaaa gtagtggttg ttccatcacc attaagagat
    19681 actgcagcag caacgacagc tgttgcgata agcaccttca ttggatcacc tttagcaaag
    19741 cgaatcatct tttcagtaat cggatcaaac aatcctgcat ctaacatgac agagaagaac
    19801 aaaatggcaa atagcaacat gatacctgtt ttagcagtat tgttgatacc atacataacc
    19861 attggtccga tagctgttag gtctttagca attccaccgt caccaacaaa ggcaacaaat
    19921 ttggcatctg cattgaagtc agctgaacca gtcagtataa cagcaatcgt catgattaat
    19981 ggaatcatga ccaaagcagt aaaaggggtc atttttttct tcattaccac gtacataaag
    20041 acaataatca tggcataagc cagcattgtt aataacatca ttgttatctc ctttttcaag
    20101 ttatgatttc agtatagatg aaagcgctta taaaataaat acttctttgt gcagaaagac
    20161 acaaaaaaaa caatttgaaa attaattttg aaaac
//
LOCUS       DAUGJR010000037        18698 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUGJR010000037 DAUGJR010000000
VERSION     DAUGJR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18698
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.037"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            47..418
                     /locus_tag="VH800_001368"
     CDS             47..418
                     /locus_tag="VH800_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8362434.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            456..1802
                     /gene="glnA"
                     /locus_tag="VH800_001369"
     CDS             456..1802
                     /gene="glnA"
                     /locus_tag="VH800_001369"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEQ8362435.1"
                     /translation="MAITVADIRREVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDEADKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(2029..3711)
                     /locus_tag="VH800_001370"
     CDS             complement(2029..3711)
                     /locus_tag="VH800_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8362436.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(3713..3943)
                     /locus_tag="VH800_001371"
     CDS             complement(3713..3943)
                     /locus_tag="VH800_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEQ8362437.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            4228..4926
                     /gene="tsaB"
                     /locus_tag="VH800_001372"
     CDS             4228..4926
                     /gene="tsaB"
                     /locus_tag="VH800_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEQ8362438.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHASLEVIIEQLVEEGQMIFVGE
                     TAPFAEKIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            4898..5353
                     /gene="rimI"
                     /locus_tag="VH800_001373"
     CDS             4898..5353
                     /gene="rimI"
                     /locus_tag="VH800_001373"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEQ8362439.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQELGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            5343..6371
                     /gene="tsaD"
                     /locus_tag="VH800_001374"
     CDS             5343..6371
                     /gene="tsaD"
                     /locus_tag="VH800_001374"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEQ8362440.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(6542..6811)
                     /gene="rpsN"
                     /locus_tag="VH800_001375"
     CDS             complement(6542..6811)
                     /gene="rpsN"
                     /locus_tag="VH800_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEQ8362441.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(7047..7790)
                     /locus_tag="VH800_001376"
     CDS             complement(7047..7790)
                     /locus_tag="VH800_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8362442.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSC"
     gene            8030..8809
                     /gene="udp"
                     /locus_tag="VH800_001377"
     CDS             8030..8809
                     /gene="udp"
                     /locus_tag="VH800_001377"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEQ8362443.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            8830..10032
                     /locus_tag="VH800_001378"
     CDS             8830..10032
                     /locus_tag="VH800_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEQ8362444.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            10062..10733
                     /gene="deoC"
                     /locus_tag="VH800_001379"
     CDS             10062..10733
                     /gene="deoC"
                     /locus_tag="VH800_001379"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEQ8362445.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(10828..11997)
                     /locus_tag="VH800_001380"
     CDS             complement(10828..11997)
                     /locus_tag="VH800_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8362446.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDVLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSADQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            12203..12733
                     /locus_tag="VH800_001381"
     CDS             12203..12733
                     /locus_tag="VH800_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEQ8362447.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFFTRLFAK"
     gene            12782..13369
                     /locus_tag="VH800_001382"
     CDS             12782..13369
                     /locus_tag="VH800_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEQ8362448.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHIIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAEPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAV
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            13518..14255
                     /locus_tag="VH800_001383"
     CDS             13518..14255
                     /locus_tag="VH800_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8362449.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
                     SSYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPR
                     TRKLTCSHCHQKSYCLELAKEDTVSRR"
     gene            complement(14312..14611)
                     /locus_tag="VH800_001384"
     CDS             complement(14312..14611)
                     /locus_tag="VH800_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEQ8362450.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDETTKKTLGAFAGKLPF"
     gene            complement(14804..15178)
                     /locus_tag="VH800_001385"
     CDS             complement(14804..15178)
                     /locus_tag="VH800_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8362451.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLENKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            15348..15569
                     /locus_tag="VH800_001386"
     CDS             15348..15569
                     /locus_tag="VH800_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8362452.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(15649..17931)
                     /locus_tag="VH800_001387"
     CDS             complement(15649..17931)
                     /locus_tag="VH800_001387"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEQ8362453.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(17953..18612)
                     /locus_tag="VH800_001388"
     CDS             complement(17953..18612)
                     /locus_tag="VH800_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8362454.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
BASE COUNT         5749 a         3242 c         3848 g         5859 t
ORIGIN      
        1 ggttattttt ttcagcctat aataaggaag atgaaaggag tttgtcatga aagaaaaaga
       61 acttagacgc tcaatggctg tttttcctat tggaacggtg atgacattaa cagatctctc
      121 tgcgagacaa attcgctatt atgaagatca aggtttaatt aagcctgaac gaacgcaagg
      181 gaatcggcgt atgttttcct taaatgacat ggaccgactt ttggaaatta aagatttttt
      241 gtctgaggga ttaaatattg cagctattaa acgcgaatat gtcgagcgtc aaggtaagtt
      301 aatgcaaaaa caaaaagctc taacagatgc agatgtcaga cggatcttac atgatgaaat
      361 gctgacacaa agcggttttt ctactccctc acagcatatt ggtaattttc gtatttaaga
      421 tatgaattgt ataaaattta aaggagacct atttaatggc aataacagta gctgacattc
      481 gtcgtgaagt caaagaaaaa aatgtaacgt ttcttcgctt gatgttcact gatatcatgg
      541 gcgttatgaa aaatgtggag attcctgcaa ctaaagaaca gttagacaaa gtattgtcta
      601 acaaggttat gtttgatggt tcatctatcg aaggttttgt acggatcaat gagtcagata
      661 tgtaccttta ccccgattta gacacttgga ttgtttttcc ctggggagat gaaaatggag
      721 cagttgcagg tttaatttgt gatatttata cagcagaagg aaagcctttt gcaggagatc
      781 ctagaggaaa tttaaaaaga gccctgaaac acatgaacga gatcggctac aaatcattta
      841 atcttggacc agaaccagaa tttttccttt ttaagatgga tgataaaggt aatccgacac
      901 ttgaagttaa cgataatggt ggttattttg atttagcgcc aattgactta gcagacaaca
      961 cgcgccgtga aattgtgaat attttaacga aaatgggttt tgaagtggaa gctagtcatc
     1021 atgaagtggc tgttggtcaa catgagattg attttaaata tgcagatgtt ttgaaagctt
     1081 gtgataatat tcaaattttt aagctagttg taaaaacgat tgcccgtgaa catggacttt
     1141 atgctacttt catggctaaa ccaaaatttg gaatagctgg atcagggatg cactgtaaca
     1201 tgtctttgtt tgataaccaa ggtaataatg ctttttatga tgaagctgat aagcgaggga
     1261 tgcagttatc agaagatgct tattatttct tgggaggact aatgaagcat gcttataact
     1321 acactgctat cactaaccct acagtgaatt cttataaacg attagttcca ggttatgagg
     1381 cacctgttta tgtcgcttgg gctggaagta atcgttcacc gcttatccgt gttccagcat
     1441 cacgtggtat gggaacgcgt ttggagttac gttcggttga tccgacagct aatccttatt
     1501 tagccttggc tgttctcttg gaagctggat tagatggtat cattaacaaa attgaagctc
     1561 cagaacccgt tgaagctaac atttatacca tgacaatgga agaacgaaat gaagcaggca
     1621 ttattgattt gccatcaacg cttcataatg ccttaaaagc tcttcaaaaa gatgatgtgg
     1681 tacaaaaggc actaggttac catatctaca ctaatttctt agaagcaaaa cgaattgaat
     1741 ggtcttccta tgcaactttt gtttctcaat gggaaattga ccattatatt cataattatt
     1801 agacttatca ggacctgctc aagttgagtg ggtcttttgg atgagctatt gtatttgagc
     1861 tagcaagcta ttattagctg atcggacacc aattgatttt ccattataga aaactaaaaa
     1921 ccagtccatg ttctatgagg actggtttta gtttgataat tatctgaact agaactgata
     1981 tgttaaagat atagacagat agtattaaga aatgagtctt atttgatttt agtgcttatc
     2041 aggtgttaag accatcggaa tgataattgg ttcacgctca gtcttttcat acaagaatgg
     2101 acgaagagca ttgacgatag caccgttaac tgattggatg ctagcatcct tattttttaa
     2161 agcaatacgg atagcgttaa agagcacacg ttggctttcg cggatcaagt cacctgactc
     2221 acgcatataa atgaaaccac ggctcagaat atctggtcca gctaaaatca tttgtgtgtt
     2281 aaaatcaaca gttgcaacag ctaagacaac accatcttct gacaaatcac ggcggtcccg
     2341 taaaacggct gctccaatat ccccgatgcc attaccatcc acgtagatgt cttgggcatt
     2401 aaagtgacca gcaatacgcg cactgtcact ggttaaagct agaacgtctc cattttccat
     2461 aataaagata ttttcttttg gaataccaat atccatcgcc agtcctgcat gaactttttg
     2521 catgcgatac tcaccatgta ctggcatgaa atattttggt ttaatcaaac taagcatgag
     2581 cttttgttct tgctgtcctc catgaccaga agtatgaata ttattgactt ttccatgaat
     2641 aacatcaaca ccagcttctt ggatggtatt gattaattta ttgacacttg tggtattacc
     2701 agggattgga cttgatgaga aaatcacagt atcaccaggc tgtaaagtta cttgacgatg
     2761 agtgccatta gcgatacgag caagtgctgc catagactca ccttgactac ctgtacacat
     2821 aattaaaact tcactagcat gaagattttt aagttcgctt ggctcaatga aggtaccttt
     2881 tggaacttta atatagccaa gttcaatacc gttaacaatt gctttttcca tagaacgacc
     2941 aaaaacggca attttacgtc ccgttttaac agcagcttct gcagcctgtt gcaaacggta
     3001 gatgtttgaa gcgaaggaag caaaaataat acgaccatga ataccttcga taatttttaa
     3061 aatggattgg ccaacaactt tttcagagtt agtaaaggtt gggatttcag cattagttga
     3121 gtctgataat aagcaaagga caccttcttc accaagcgct gccatacgtt gtaaatctgc
     3181 aggatctcct actggcgtga agtcaaattt aaaatcacca gtacagataa tcttaccttg
     3241 aggggtgtgg ataacaatac cgaccggttc tggaatggaa tgagtagtct tgaagaaagt
     3301 gacgctcatg tttttaaaag ttaactcggt gttgtgattg atttcgtaaa cagttgcttc
     3361 acgccaaaga ccatgttctt ccaatttacc acggataaga gcaagtgcta aaggtcctgc
     3421 gtagataggg atattagcct gtttgagaag aaatggaata ccaccaatgt ggtcttcgtg
     3481 accatgtgta ataacaagag ctttgacccg gtctaagtta tcgacaatgt aagaatagtc
     3541 tggaataacg taatcaattc ccaaaagatc atcttctggg aatttgatac cggcatcaac
     3601 gataatgatt tcgtcttgat actcaatacc ataagtattc ttcccaatct ctcccagacc
     3661 accaatggca aacaccccaa cttcattagg ttttaaactg atatttgtca tcttagaact
     3721 ccgttaattc aaaaacaccg gtctcttttt cgtaatcgag gtgtttgtca gaaagtagct
     3781 cgataaattc cacgttataa taggtgttat cttcaacgag acgacgagcc ttgatacggc
     3841 catcgagttc atcagtagca tcaatattaa gatagagtgc tttagtactt tcacgacgtg
     3901 ggctttgatc ctttgtttct tgatagaaaa ctttataaat catttgtttt taaattcctt
     3961 tcgttatgaa tcaattatcc aaacaataat aaataggtca aaaggtaggt gttccatttt
     4021 gacggtttta tatgttgtca ttattgtgta gtagattaat tcctgattct gtgcaattat
     4081 tacaattata ccataaactt agcttttagt aaaaaattta ggtacattta tggtatagtc
     4141 taaatcaaat taagagtcag cctttttgtt tatgattctt aatttgtgtt ataattgata
     4201 ctagaacttg cagtagaaag gcataaaatg aagacacttg catttgatac ctcaaataaa
     4261 accttgtccc ttgctatact tgatgatgag acacttctag cagatatgac ccttaacatt
     4321 cagaaaaatc atagtgttag ccttatgcct gctattgatt ttttgatgac ttgtactgat
     4381 cttaaacctc aagatttaga aagaatagtg gttgcaaaag gccctggatc ttacacaggt
     4441 ttacgagtgg cagttgctac tgcaaaaacg ttagcgtaca gtttaaatat tgcattggtc
     4501 gggatttcga gtctatatgc tttggctgcg tctacttgta aacagtatcc aaatactttg
     4561 gtggtgccat tgattgatgc tagaaggcaa aatgcgtatg taggttatta tcggcaagga
     4621 aaatcagtga tgccacaagc ccatgcttca ctagaagtta ttatagaaca attagtagaa
     4681 gaaggacaga tgatttttgt tggggagact gctccttttg ctgagaaaat tcaaaagaaa
     4741 ctacctcagg cgatactact tccaaccctt ccttctgctt acgaatgtgg tcttttgggg
     4801 caaagtttgg caccagaaaa tgtagacgcc tttgtccctc aatatctcaa gagagtggaa
     4861 gctgaagaaa actggctcaa agataatgag ataaaagatg atagtcacta cgttaagcga
     4921 atctaatatg aaaacagttg aagaacaagc aaaaaatatt tatcagcttt tggaaatggt
     4981 ttatggcacg tctccttgga ctttagaaca agtattaatc gatatacggc gggatcaaac
     5041 agattatttc ctactatatg atcatgataa attgctaggt tttttagcta ttcaagattt
     5101 agctggtgaa gttgaaatga ctcaaattgc tatactacct agtcatcaag aacttgggct
     5161 agcgtctcaa ttgatgacgc atttagatag cattgaaagt gacatctttt tagaggttag
     5221 agaatctaat catagagcac agggtttata tcagaagttt ggttttaaat ttattggcaa
     5281 aagaccagac tactatagaa atcctataga aacagcttta ttgatgaaac gggaaggaaa
     5341 acatgacaga taggtatatt ttagcagttg agagttcttg tgatgagacc agtgtagcga
     5401 ttttaaaaaa cgaaagtacc ctcttaagta atgtcattgc aagtcaggtt gagagccaca
     5461 aacgctttgg tggtgtggtg ccagaagtag ctagtagaca ccatgtcgaa gtgattacga
     5521 cttgctttga ggatgctttg caagaagctg gcatcagtgc ttcagattta tcagcagttg
     5581 cggtaactta tggccctgga cttgttggag ccttgttagt tggattagca gctgcgaagg
     5641 cttttgcttg ggcaaatcat ttacctttga ttccggttaa tcatatggca ggtcacttaa
     5701 tggcagcgcg tgaacaaaag cctttagttt atcctttaat agcactgttg gtttcaggag
     5761 gacacacaga attggtttat gtcccagagc caggggatta tcatattatt ggcgagacgc
     5821 gtgacgacgc tgttggtgag gcttatgata aagttgggcg tgtgatgggc ttaacctatc
     5881 cggcaggacg tgaaattgac cagttggctc ataaaggtca agatacttat catttccctc
     5941 gtgctatgat aacagaagac cacttagaat tttccttttc aggactcaag tccgctttta
     6001 tcaatcttca tcataatgct aagcaaaaag gcgatgaact gattctagaa gatttgtgtg
     6061 catcttttca agcagctgtt ctagatattt tattggccaa aacaaaaaaa gctctgagca
     6121 gataccctgc aaagatgctt gtagtggctg gtggtgtagc ggcaaatcaa ggattacgag
     6181 atagattagc acaagaaatt acacatatag aagttgtgat tcctaaacta agactctgtg
     6241 gagataacgc gggtatgatt gctttagcag cagctattga gtatgacaaa cagcattttg
     6301 ctaatatgag cctaaacgcg aagcctagtt tagcttttga ccagtttcca gacagttttg
     6361 taataaacta gtcacacttg ctagttagta agatttataa tggataagaa tctccctttg
     6421 aaaaaacaac ccggtatctt ggcataccgg gttgtcatga tgataagtaa ttggcttcta
     6481 tggttactaa taattcagat aattacctgc aaaataattg tctgcctaag gtgaagtaag
     6541 cttaccagct agctttagtg acgccaggaa gctgtccttt gtgagctaag tcacggaaat
     6601 tgatacggct aacaccaaac ttacgcatgt aagcatgagg acggccgtca attttgtcgc
     6661 ggttcttcaa gcggtttgga tttgaatcac gaggcaattt gcgcagtgat tcataatcgc
     6721 ccttcgcttt taagtcacga cgaaggtcag cgtactgttc aatcagttgg agctgctttt
     6781 ggtatttagc aatttttgac ttttttgcca ttgctttctc cttcttaata tttaataacc
     6841 tcagagtcgt tatcagcgct ctgaatccac ttaactggta tttaactggt taagtggata
     6901 tataatcatt atacaataaa taaaagcaaa agcaaataaa aaaaattaac tagttatctt
     6961 ttttagccat aatatcaaaa aactccacat ctaagtgtgg gagtcaggta ttaataactg
     7021 tttaaaggtg tttaatgagt gtcgctttag caactttgag attgaacttt taagtcaaat
     7081 aaatcagcag gaacgtagtg tttggttgag accaagatgt ctttaccatt gtagagagtt
     7141 tcttggatta aaataaaagc actattttct gatagagtat acttagttgc tgtgtaattg
     7201 ccagtcttgg tatagccgat ttggttgcag gaatgagaag ctttaccaga ttcatagatt
     7261 ttctcttcta agaaagtaag aaggggctct tcttgattga gatttatagc atatttagaa
     7321 ataacctcaa tagggataaa agataaacta taagcaatag ctttattttg gctatgatac
     7381 cagcgatcaa caataatcac aacaggagtt tcttgtttta gggatgctgt aatggcaaca
     7441 gtgggcactt caatccgata ttccaactca acctttgtga tgtcagatga taggcttgca
     7501 tatatggggt gttgaagata ttcgaaacct tggtgatatt tagtttcagg agtcttgagt
     7561 ataaaatttc cctttcctct gatatttttt atgagatgat cctcttggag gagggctagg
     7621 gatttacgta gtgtcatccg actgacattg agctgtctag caagttcagg ttctgatggc
     7681 agttgcatgc caggactata tgtaccatct tgaataagtt gaaaaatagt attatatact
     7741 tgcacatgtt taagtttttt gagttttttg gttaagtcgt tagtagacat atcacttacc
     7801 tcattaataa tctttagtgg agtttaactt gtctaaaaac tattttagca ctaacagtat
     7861 tccttgatta gaattgtacc catctatagt gttagtatct cacactcagg tactttttgt
     7921 caaaaaagag atgaaaaaca ccttaaaaaa gcgtttacaa aatagagtgt gtgtgatact
     7981 atacaagtgt atcaaaaatt agacaagtaa aatacaggag gtttttaaca tgcaaaatta
     8041 ttcaggtgaa gtcggattgc aatatcacct acagattcgt ccaggtgatg taggtcgtta
     8101 tgttatcatg ccaggtgatc caaaacgttg tgcaaaaatt gcagaacatt ttgataatgc
     8161 agttcttgta gcagacagcc gtgaatatgt tacgtataca ggtacattaa acggtgaaaa
     8221 agttagtgtt acttcaactg gtattggtgg tccatcagcg tctattgcga tggaagaatt
     8281 gaaactttgt ggcgctgata cctttatccg tgttggaaca tgtggtggta ttgaccttga
     8341 tgttaaaggc ggagacatcg ttattgcaac tggagctatc cgtatggaag gtaccagtaa
     8401 agaatatgct ccgattgaat ttcctgctgt agctgacttg gaagtgacaa atgctctagt
     8461 taatgcagct aaaaagcttg gttatacaag tcacgcagga gtagttcaat gtaaagatgc
     8521 attttacggg caacatgagc cagaacgtat gccagttagt tatgaattat taaataaatg
     8581 ggaagcatgg aaacgtctgg gaacaaaagc gtctgaaatg gaatctgcag ctctttttgt
     8641 agcagcaagt catctaggag ttcgttgtgg atcagatttc cttgttgttg gtaatcaaga
     8701 acgcaacgct ttgggtatgg ataacccaat ggctcatgat acagaagcag ctattcaagt
     8761 tgctgttgaa gcactccgca cacttattga aaatgataaa tcacaataag cgaggttttg
     8821 gaagtcatca tgcaatttat ttatagtatt attggtattt tattggtatt aggaattgtg
     8881 tatgcaattt ctttcaatcg taagagtgtt tctctaagtt taattggaaa agctcttatc
     8941 gttcaattca ttattgcgct aatcttagta cgtatcccac taggccaaca aattgttagt
     9001 gttgtttcaa ctggagttac tagcgtaatc aactgtggtc aagctggttt aaattttgtg
     9061 tttgggtcat tagcagatag tggcgcaaaa actggtttta ttttcgctat tcaaacgctt
     9121 ggtaatattg ttttcttatc tgccctagtt agtctacttt attatgtagg aatccttgga
     9181 tttgtagtaa aatggatagg taagggcgtt ggtaaaatta tgaaatcctc agaggttgag
     9241 agttttgttg ctgtagctaa tatgtttctt ggtcaaacag acagtccaat cttggttagc
     9301 aaatacctag gtcgtatgac tgatagtgag ataatggttg tgttggtatc aggtatggga
     9361 agtatgtcag tttctattct tggtggctat attgcattag gcattccaat ggaatatctc
     9421 ttgattgctt caacaatggt tcctattggc agtattctca ttgctaaaat cttattgcct
     9481 caaacagaac ctgttcaaaa aattgatgac attaagatgg ataataaagg taataacgcc
     9541 aatgtgattg atgcaatcgc tgagggtgca agcacaggtg cacaaatggc tttctcaatt
     9601 ggtgctagtt tgattgcctt tgttggttta gtttctttga ttaatatgat gttaagtgga
     9661 ttgggaatcc gcttagaaca aatcttttca tatgtttttg ctccatttgg ttttcttatg
     9721 ggatttgacc acaaaaacat tcttctagaa ggaaaccttc ttggaagtaa gttgatttta
     9781 aatgagtttg tttcgttcca acaattgggt cacctaatca aatctttaga ttatcgtaca
     9841 gcattggtag caactatttc actctgtggt tttgctaatt tatcaagttt aggtatttgt
     9901 gtttcaggta ttgctgttct ttgcccggag aaacgtagca ccctagctcg acttgttttc
     9961 cgtgcaatga ttggtggtat tgctgtaagt atgcttagcg cctttatcgt cggtattgta
    10021 actctattct aaacgttgac aaaagaaaga aggatagtaa cgtggaagta aaagatattt
    10081 taaaaacggt agaccatact ttgctagcaa caacagcaac gtggccagaa atccaaacaa
    10141 ttttagatga tgccatggct tatgaaacag cttcagcatg tattccagct tcttacgtca
    10201 aaaaagcagc agaatacgtt tcaggtaaat tagctatttg tactgttatt gggttcccaa
    10261 atggctatag tacaactgcg gcgaaggttt ttgaatgtca agatgctatt caaaatggtg
    10321 ctgatgaaat tgacatggtc attaatttga cagacgttaa aaatggggat tttgatactg
    10381 ttgaagaaga aattcgtcaa atcaaagcta aatgtcaaga ccatatctta aaagttatcg
    10441 ttgagacatg tcaattaact aaagaagaac ttatcgaact ttgtggagtt gtcacacgtt
    10501 caggtgcaga ctttattaaa acctctactg gtttttcgac agcaggtgct acatttgaag
    10561 atgttgaagt gatggcaaaa tatgtcggcg aaggtgttaa aattaaggca gcaggtggaa
    10621 tctcatcatt ggaagatgct aaaacattta ttgctttagg agcttcacgc ttgggtacta
    10681 gccgtatcat caagattgtt aagaacgaag ctacaaaaac cgatagctat taacttaatc
    10741 ataccgattt agcttgagac taaaacaaaa aactcatata ataggagtta aaaagcctac
    10801 tatcttagtg ataataggct tttttagcta tgaagacttc cctgcgatcc atcctgaaca
    10861 aagagctgag gtaatattaa accctccggt atgagcatta atatctaaga cctctccagc
    10921 gaaatacagg ccaggaactt tcttgctttc caaggtttta gggttgattt cttttaaatc
    10981 tacgcctcct ttggtcacaa atgatttagc caaagacatt tttcctgtaa tgggtatctg
    11041 gaggtgtttg agtttatcaa gcaattcctt ttcttgtttt ggagagagtt gtttgacctt
    11101 ttcggggtaa tcttctgata aaaaatcagc tactcgttca ggcagtaggc ctttaagagc
    11161 atttttgatg tttttatcac gttgatcact cagataagcg gttaagtcat ctgttgataa
    11221 gtgtggcaaa aagtccagct ctgcaatttc tccacctttc acaaaagagg acagacgaag
    11281 agctgcaggt cctgaaaggc caaagtgggt gaagagtaag tcgtgtgtga tgacgtgttt
    11341 gtcataacta agagtaacgt cgtctaggga aataccttgc aagactttgt gaggaaaatc
    11401 agttaacaga gggctctcag cagcttctaa atcagtcacg gtcagtttaa aatgccgtgc
    11461 aatatcatgt ccaaaacctg ttgaacccgt tgaagggtag gacttgcctc ctgtggtcac
    11521 aatcaatttt tggcaggtga aagtctggtc tgcagatttg aggtagaaga ggtcatcttg
    11581 ttttttaacg gaaaccactt cagtgctggt tagcacctga cccccaagag ccttgatttt
    11641 tttctccaga gcatcaatga ttgtccttga tttatctgtt gtggggaaca tccgtccatg
    11701 gtcttcttct ttgagtttga cgccgttttc ctcgaaaaag gcaatgatgt catggttgtc
    11761 aaactgggaa aaaacactat ataaaaagcg gccatttcca ggaatgccag ccataaggac
    11821 atcaaggtta ccactattag tgacattaca gcgtccacca ccggttcccg ctaatttttt
    11881 gcctaagcgg cgattttttt caattaagag agttttatag ccatagtagc tgctggagat
    11941 ggcggccatc atgccagcag ggccacctcc aataataatc gtatcgtatt gagtcatagc
    12001 cttattttag cataaaagcg ggggatttaa tagtcaggta aatgaactaa catggcatac
    12061 cgttttttac gcatttaaac aatgctttca agtaataatt gatgcctttg gcacgactga
    12121 aatgaggtca aattgacaga atactcctat tatggtacta tttttaataa gaatattcag
    12181 tgatagtgat aaagaggaaa atatgggaat tgaaaagaca gttagtgaac tagctgatat
    12241 tttgggagtg agtcgtcagg ccgtcaataa tcgtgttaag tctttacccg aagaagatct
    12301 tgacaaaaat gaaaaaggcg ttactgtggt taagcgcagt ggtcttgtta agctggaaga
    12361 gatctataaa aaaacaattt ttgacgatga gcctatcagt gaagaaacga aacaacgtga
    12421 gcttttagag attctcgtgg atgagaagaa cactgaaatc acgcgccttt atgagcaact
    12481 caaagccaaa gatgctcaac ttgcctcaaa agatgagcaa atgcgtgtta aagacgtgca
    12541 gatcgctgaa aaagataaac aattggatca gcagcaacaa ttaactgcta aagccatggc
    12601 tgataaagaa accctaaaat tagaattgga agaagctaaa gcagaagcca accaagctcg
    12661 cttacaagtc gaagaagttc aggctgaagt tggccctaaa aaaggctttt tcacccgctt
    12721 gtttgcgaaa taatcacaaa aaatgacgaa ggccctatca gggtcttttt tggaggaaaa
    12781 catgaaacac ttagatactt atattgcctt tgatttagaa tttaacactg tcaatgacgt
    12841 tagtcatatc attcaagtat cagcagtcaa atatgaccac cataaagaag ttgacagctt
    12901 tgacacctat gtttacacag atgttccctt acagagcttt atcaatggcc taacaggaat
    12961 cacatctgac aagattgctg cggaaccaaa agtagaggag gttatggctg cgtttaaaaa
    13021 ttttgtggga gagttaccac tgattggtta taatgctcaa aaatctgacc tgcctattct
    13081 agctgaaaat ggcttggatt taagggacca ataccagatt gacctctttg atgaagctta
    13141 cgatagacgt agcgcagact taaatgggat tgctaacctt cgtctgcaaa cagtggcaac
    13201 ctttttaggc attaagggtc gaggtcataa tagcttagaa gatgccagaa tgacagcagt
    13261 aatctataag tcttttttag aaacagatac aaacaaagca tatctcagcc agcaagaaga
    13321 ggtaaccaca gataaccctt tcgcagcttt gggagacttt ttcgactaaa ggctctgcta
    13381 tttttgaaaa ataaaaaaat tcctagggtt agcccttgct tataacgcta ggtcatgtaa
    13441 gataggggca tatcaagagg gagtcgggtg cacacgagtt gcttttgatc actaaatgat
    13501 agaaagaagg tgtggaaatg tctcaattct attcgactgg agaattggcc aacttagctg
    13561 gcgtttctat tcgaactgtc caatactatg accaacgtgg gattttgatt ccgacagcat
    13621 tgacagcagg tggacggcga ctctatacgg attctgattt agaacaatta cgcatgattt
    13681 gctttctgcg cgatttggga ttttccattg agcagattcg caaagtctta gcagaggaaa
    13741 atgcagccca ggtgctggaa ttgcttctag ttgatcatat tgcgactgcc aaggaagact
    13801 tggctgcaaa agagcaacaa gttgacatag ctgtcaagat acttgacaga cttcgaaaac
    13861 aagaccccca gtcactagat tttctgatgg acatttcgct tagcatgaaa aatcaaaaag
    13921 cttggaaaaa attacaatgg aagatgggta tcagtatatt tttagccatt gtttcatatg
    13981 taggacttat tttactatct agttatctgc aaaaattttg gttagtttat gttgctatgg
    14041 gactatttct accaggtttc agttggttgg taatttattt taggaagcaa tttatttatc
    14101 tctgtcccca ttgtcatcag aaatttgaac ctagctttaa tgaatttgcc cttgcaggcc
    14161 atacaccacg aaccagaaag ttaacctgct cccattgcca tcaaaaatcg tattgcttgg
    14221 aactggcaaa agaggacact gtctcaagaa gataagcact aactcataaa aaaactagcc
    14281 tgagatcctt ctcaagctag tttttgtttt tttagaatgg taatttacca gcaaaagcgc
    14341 ctaatgtttt cttagttgtt tcatcaattt gcgtaagggc atcattaatg gcttgagtgg
    14401 tcatgtcttg aagcgtttct acatcttcag gatctacaac agcttctttg aagtcaatcc
    14461 caaccaattt tttatcaccc gtgaaagtgg cagtgacaag gtcttgagct gattttccag
    14521 taaattgcat agcagccaaa tccgcctgct tttgctccat ttgtttctga agcttttgtg
    14581 cttgcttcat catgttttgc atgttcatca taagactata ctctccttaa tttaatacta
    14641 actattataa cacataaaaa gaggcaataa aaacaatgtc agttagtaga ctagcctgta
    14701 tcagtaagaa agtcgctatg gataagatgg attagcagca agggtctggc taatgacaga
    14761 ataagtctag aaatgaacta tttttgtcat agactagtcc gacttagtgg ttatctaatt
    14821 cacgatcttc tttagcttgt tgttctaaaa gaatttgtgc gaagtcaacc cacttagtgt
    14881 agttattttc ggataattgt tctgaaatca tcgctaactc tcgttgtggc aactgataag
    14941 agactccctt attttctaag gttaaatctt cttccattag ggcggttaaa ctaacatcaa
    15001 agatagcagc aatatcactt aatagaccag actttggagt atattttcct ttttcccact
    15061 cactgattga agaagagctt tttcgtccta ggagattagc aagttctaat tgttccatgt
    15121 tcttttttaa tctaaggtac tttaaattac ttgcaaaaaa agttttcttg gcggacatat
    15181 ttttctcctt ttctttatat aaaatatgat accataaaag aggttaaagc aaaaggtatc
    15241 gtaaaagatg gtctaaaaac tctctaaaaa cttgacttca taaaaaccga agtttataat
    15301 aaacttaaca tgattaacta atctcatttt agtgtggagg gaaaattgtg accaaatcaa
    15361 ctttaaaaga gttaagaaca acaaagaaaa tgacacagca ggaattgtct cacttaacag
    15421 gtatttctgt cagaacgatt gctaggtatg aaaaagatac taaaaagcta aggcgagcaa
    15481 aatatgagaa gctaaaaggt attgcacaag cattagcggt ttccgttgat gatatttttt
    15541 taggaataga ttcggaattt atgaactaag acgatcgttt tctgtttgct attagtaaga
    15601 ccaattaaca aaaaagtgct tagttatatt gctaagcact tttctttgtt aatttgatgc
    15661 tattggcaca atcaattgag actgactgag atcgatagtt aaagcatagt tgctgttgtc
    15721 acggacagta tgttcaaaat cggttgtgta taagatgact cgaagggtat ctcctttttc
    15781 tagatgatag atggttggtt gcaaaggaag tctaacagtc atccatttat tattaggaat
    15841 agtttcaatt gacgacaaat tattgcgatt ttgtaaattc atgaaacctt tcgaaataac
    15901 acggtaagaa tcttctctaa atggtagctc tttaaggggt tccctagaga aattttgccc
    15961 attgtcaata cttgattggg tgagagcaat aggaagatcg cccaagcgtt ttttcttacc
    16021 atagtcaagg atttgtgcag atagaagtcc tttattttca cttgatttca cttttaactg
    16081 taggacaatt tcaccgttaa taggtaagtc ctcttccagt aaaatatcaa tcagggcttg
    16141 attggccttg cctttaaaga gagctgcttt gaacgcacgg aaatctttac cgtaagcttt
    16201 aaattcatct tcaccatagt gattatcaat taaaagcagt tcctgaccga ggtcaagctc
    16261 tttgatggtt gaggttccaa agactttacg ctcctgccag ttttgtgggc aggtgttatc
    16321 ctgccagatc atttcaggaa ggctaaaatc attagctagg cctaagagtt tttgacataa
    16381 aagggcattc atgctttcgc gaaaatcaat ggattgccaa ttatgcatgt aaacatgctc
    16441 accttgatgt aaaaagaggt gcttgttgat tgtggaagga agcgcattga aaatctcata
    16501 gacctgtctt ggtttgacat tccagtcttg taagccatga gtataaacga catcacactt
    16561 tatttgatga gcatttttta agtaattgcg gtcgtgccaa aattgattat aatcaccaga
    16621 ttgtcggtct aacgcctgag actgttggtt tagcaattct tgataacgat cattatggcg
    16681 aagataatcg ccagccaata aattacgcga gtaggtgagc tcagttagga catctagatc
    16741 ctctccagga tagccaccag gactacaaac taagccattt tcgcggtagt agttgtacca
    16801 agaagaaata gctgattctg caataatcat ggctaatccg tctacgcctg tagtggctaa
    16861 accagtagac atagttccca agtaggactt tccagtcgta caaactagac catttgccca
    16921 atcagctctc acttggtggg tttttgagtg gctggtgtag gctgtggctc ttccatttag
    16981 ccaatcaata acggctttaa agctttcaat ttgagcatag tttccactcg tcataaagcc
    17041 agtggaacca gcagttccca cacctgaaac atagatatta gcaaacccac gtgcgaggaa
    17101 ataatcgttg aggctatagg agttaatgta gctaaagctt tctagatttt gacctatagg
    17161 aagtttgcaa ggctgtgtct caagaggaat aaaatccctg tcttcgacag tgatttgtct
    17221 ccttttttta acgactaact ctttttccat acgataaagt tttttgtcgt tggctacttc
    17281 attgatacct tgatggtatg gactaggtgt catcaaagtt ggtaatggtt tttgagatgg
    17341 aggacgaatg atattaacct taataagatc aagttggcca tcttgatcgg tatcaagagg
    17401 tgcttcaacg taaacaactt ctcgaatcag ctgtgacgtg tcaaaggtag ctaatgattt
    17461 accgttgaag aagtggtaat cattgtccat agtaagcatt ccttggctga ccaaatcatc
    17521 aatcagggtc atgccagact tacaacgggt cgctaataag tggtggatat gcttgataat
    17581 ttctgtttcg tcaaagtgga taggaaaggc cagtttatca aggaaagcat cggcctctgt
    17641 aaaatcaact ccaggaataa agccaaggac ttgcagggcc agtaaatcaa aaacctcttt
    17701 ggataactct tgctctgatt gaaaaaagct caatgcgtcc atgtcatttt tggcgattag
    17761 atgacttaaa ggataatcac tatcagggta gtggaagaag agtttacgta aaaagctttc
    17821 taggctagct ttggcagttt tttgcagatc cagatcaaag cccaattctt ttaattcttc
    17881 agccgctctt tctagactag ttggaatata ggaaaattga ttatagcgca taggagtttc
    17941 ctttctagtg gcttagaaaa cgatattatc ttttaattta tcaagattgg taatgataat
    18001 atgttgttta tcaatgcgaa tgatgttttt ttctttcaac tgttttagaa tacggctgac
    18061 gctgctagcg gtagaaatgc cacagaattt accgagttcc tcattagtaa tgacaaaatt
    18121 aattaaaatt tggccatttg gtagttcttc gccaaatagg gtcattaagt catatatttg
    18181 agtagaaatg gcaccgatac ggccgttagt taacatacat tgcatttttt tcatggattt
    18241 ttgaagacga ttatggtaaa agtccttcac atatccttgt agttcaatat cttcgtttat
    18301 atcttttaaa aatgctgagc ggcgaacctt gtaaaaacta gctttctctg actcgatgcg
    18361 aacattataa ggctctccca tatcttttga ataaccagtg ttgagaacag aagtaatttc
    18421 aagtcctgta acatatctca aattaaattc cattccatat tttgaaagaa cactctgttt
    18481 cacaatgccg tcttttaaaa tataagtgaa gtcctcttcg agactttcaa aagtcaagta
    18541 cttgtgataa cttttttcaa tgataggaaa gttatgatta tcaatatacc gttgcaaaat
    18601 gtgatgattc acgcttttct ccaaatattc ttttaccaat gtataatttg tatcttcaag
    18661 agaaattaac atttgctaat gccctttgat agtaacac
//
LOCUS       DAUGJR010000038        18604 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUGJR010000038 DAUGJR010000000
VERSION     DAUGJR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18604
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.038"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            33..1355
                     /gene="ska"
                     /locus_tag="VH800_001389"
     CDS             33..1355
                     /gene="ska"
                     /locus_tag="VH800_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEQ8362455.1"
                     /translation="MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQL
                     VVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEK
                     ADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQE
                     FLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGD
                     TITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQ
                     AYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVT
                     VYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK"
     gene            complement(1453..1896)
                     /locus_tag="VH800_001390"
     CDS             complement(1453..1896)
                     /locus_tag="VH800_001390"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEQ8362456.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     SQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(1911..4130)
                     /locus_tag="VH800_001391"
     CDS             complement(1911..4130)
                     /locus_tag="VH800_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEQ8362457.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGHDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            complement(4382..5428)
                     /gene="slc1"
                     /locus_tag="VH800_001392"
                     /gene_synonym="slcA"
     CDS             complement(4382..5428)
                     /gene="slc1"
                     /locus_tag="VH800_001392"
                     /gene_synonym="slcA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin Scl1"
                     /protein_id="HEQ8362458.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEVSSTTM
                     TSSQRESKIKEIEESLKKYPEVSNEKFWERKWYGTYFKEEDFQKELKDFTEKRLKEIL
                     DLIGKSGIKGDRGETGPAGPAGPQGKTGERGAQGPKGDRGEQGIQGKAGEKGERGEKG
                     DKGETGERGEKGEAGIQGPQGEAGKDGAPGKDGAPGEKGEKGDRGETGAQGPVGPQGE
                     KGETGAQGPAGPQGEAGKPGEQGPAGPQGEAGQPGEKAPEKSPEGEAGQPGEKAPEKS
                     KEVTPAAEKPADKEANQTPERRNGNMAKTPVANNHRRLPATGEQANPFFTAAAVAVMT
                     TAGVLAVTKRKENN"
     gene            5810..6292
                     /gene="nrdI"
                     /locus_tag="VH800_001393"
     CDS             5810..6292
                     /gene="nrdI"
                     /locus_tag="VH800_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8362459.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGDVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            complement(6686..7504)
                     /locus_tag="VH800_001394"
     CDS             complement(6686..7504)
                     /locus_tag="VH800_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEQ8362460.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMDDETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKGADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLGWR"
     gene            complement(7587..9773)
                     /locus_tag="VH800_001395"
     CDS             complement(7587..9773)
                     /locus_tag="VH800_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8362461.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDACMTRLRVTVKDP
                     AKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLT
                     SKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL"
     gene            complement(10130..10879)
                     /locus_tag="VH800_001396"
     CDS             complement(10130..10879)
                     /locus_tag="VH800_001396"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEQ8362462.1"
                     /translation="MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLADEAEVVLVFDDG
                     VKYLAKVTNSMAHELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAASAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            complement(10879..11832)
                     /locus_tag="VH800_001397"
     CDS             complement(10879..11832)
                     /locus_tag="VH800_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEQ8362463.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADIIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            complement(11903..12373)
                     /locus_tag="VH800_001398"
     CDS             complement(11903..12373)
                     /locus_tag="VH800_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEQ8362464.1"
                     /translation="MATYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEAASYPYPRY"
     gene            12573..14330
                     /gene="pabB"
                     /locus_tag="VH800_001399"
     CDS             12573..14330
                     /gene="pabB"
                     /locus_tag="VH800_001399"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEQ8362465.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDL
                     IDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFL
                     EQHLNRLKEAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            14363..14929
                     /locus_tag="VH800_001400"
     CDS             14363..14929
                     /locus_tag="VH800_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEQ8362466.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            14962..16230
                     /locus_tag="VH800_001401"
     CDS             14962..16230
                     /locus_tag="VH800_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEQ8362467.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDGSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            16319..16515
                     /gene="ssrS"
                     /locus_tag="VH800_001402"
     ncRNA           16319..16515
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VH800_001402"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            16516..16588
                     /locus_tag="VH800_001403"
     tRNA            16516..16588
                     /locus_tag="VH800_001403"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16549..16551,aa:Lys,seq:ctt)
     gene            16727..17167
                     /locus_tag="VH800_001404"
     CDS             16727..17167
                     /locus_tag="VH800_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8362468.1"
                     /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KEDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLAFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            17222..17728
                     /locus_tag="VH800_001405"
     CDS             17222..17728
                     /locus_tag="VH800_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEQ8362469.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERS
                     DHDMIADLSTCLLKQDLIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLN
                     YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVVQKYSHKTIVLTNQKQL
                     SHYMNTIN"
     gene            17977..>18604
                     /gene="smeZ"
                     /locus_tag="VH800_001406"
     CDS             17977..>18604
                     /gene="smeZ"
                     /locus_tag="VH800_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal mitogenic exotoxin SmeZ"
                     /protein_id="HEQ8362470.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKDGDKIAMFSVPFDWNYL
                     SEGKVIAYTYGGMTPYQEEPMSKNIPVNLWINRKQIPVPYNQISTNKTTVTAQEIDLK
                     VRKFLISQHQLYSSGSSYKSGKLVFHTNDNSDKYSLDLFYVGYRDKESI"
BASE COUNT         5299 a         4264 c         3604 g         5437 t
ORIGIN      
        1 ggggattgaa acttaacttt taggaggttt ctatgaaaaa ttacttatct attggagtga
       61 ttgcactgct gtttgcatta acatttggaa cagtcaagtc ggtccaagct attgctgggt
      121 atggatggct accagaccgt ccacctatca ataacagcca gttagttgtt agtatggccg
      181 gtatcgttga aggtaccgat aaaaaagttt ttataaattt ttttgaaatc gatctaacat
      241 cacaacctgc tcacggagga aagacagagc agggcttaag tccaaaatca aaaccatttg
      301 ctacagataa tggcgcaatg ccacataaac ttgaaaaagc tgacttatta aaagctattc
      361 aaaaacagct gatcgctaac gttcacagta acgacggcta ctttgaggtc attgattttg
      421 caagcgatgc aaccattact gatcgaaacg gcaaggtcta ctttgctgac aaagatggtt
      481 cggtaacctt gccgacccaa cctgtccaag aatttttgtt aaagggacat gtgcgcgtta
      541 gaccatataa agaaaaacca gtacaaaatc aagcaaaatc tgttgatgta gaatatactg
      601 tacagtttac tcctttaaac cctgatgacg atttcagacc agggctcaaa gatactaagc
      661 tattgaaaac actagctatc ggtgacacca tcacatctca agaattacta gctcaagcac
      721 aaagcatttt aaacaaaacc cacccaggct atacgattta tgaacgtgac tcctcaatcg
      781 tcactcatga caatgacatt ttccgtacga ttttaccaat ggatcaagag tttacttacc
      841 atgtcaaaaa tcgggaacaa gcttatgaga tcaatcctaa aacaggtatt aaagaaaaaa
      901 cgaacaacac tgatctggtc tctgagaaat attacgtcct taaacaaggg gaaaagccgt
      961 atgatccctt tgatcgcagt cacttgaaac tgttcaccat caaatacgtt gatgtcaaca
     1021 ccaacgaatt gctaaaaagc gagcagctct taacagctag cgaacgtaac ttagacttca
     1081 gagatttata cgatcctcgt gataaggcta aactactcta caacaatctc gatgcttttg
     1141 atatcatgga ctatacctta actggaaaag tagaggataa tcacgataag aataatcgtg
     1201 tcgttacagt ttatatgggc aagcgcccta aaggggcaaa gggtagctat catttagctt
     1261 atgataaaga tctctatacc gaagaagaac gaaaagctta cagctacctg cgtgatacag
     1321 ggacacctat acctgataac cctaaagaca aataaccacg atcttctaaa atgatgagat
     1381 taactgacaa aaaaagcaag caacacgcta tcaacagttg cttgcttttt tctaacctct
     1441 tagttgtaga gactagtgac atttcgtgtc taaaataatc gtaactggtc catcattgat
     1501 gagactaacc tgcatatctg ccccaaaaac gccacgctca actggcacaa actctgccaa
     1561 ttgttcatta aagctatcat acaactgact agccaaatct ggcttagcag caccagtaaa
     1621 ggcaggacgg tttccctttt tggtgtcagc ataaagggta aattgcgaca cagataagat
     1681 actgcccttg atgtcttgga tagactggtt catcttgcca tcagcatctg aaaaaatgcg
     1741 catgttgact atttttcgca cagcgtaagc caaatcttct gcattatcat ctggtcccac
     1801 acctactaac aacaacaacc cttgattaat agcgccagca attttcccat caatagaaac
     1861 agaggcctct ttgacccgtt gcaagacaag tttcatgttt ttatcctttc ttagccattg
     1921 gtccgcttca cgctataaac atctggaact gccttgattt tttcgacaac agtggtcaga
     1981 tgcgtcagat ttggaatgcc aaagctcacg tgaatattag caaacttcat gtccttggtc
     2041 ggctgagcat tgactgtcga tatgctcttg gttgagtttg ataaaatttg gagcacatca
     2101 ttaagcagac cactacgatt gagcccatag atatcaattt cagcctgata atctttactc
     2161 gaattgtcca aatcccactc gacctcaatc aagcgttctt ggtagccatc ttgactctta
     2221 atgttatgac agtccgatct gtgaatcgca atgccacgcc ctttggtaat gtagccgtca
     2281 ataggatcac caggtacagg attacaacac ttggcaatcc gcatcaagag gcctgatgct
     2341 ccttggataa tgactccatt ttcactgcga accttgagca catctttgtt ttcgtgtttg
     2401 acctcaccgc ccttaaccaa ttcttcagct tctgctttag ccttggccct ttcttcttca
     2461 cggcgctctt tttcggttaa cttgttaaag acactgatag gactaatgtc accaaaccca
     2521 acggctgcat agagtgattc ttcgctcttc acactgactt ttggaaggat ggcttcaatg
     2581 cgttttttgt caaggtattt attggcaacg tagccctgct cttgaaaata agacaccaac
     2641 aaatcacggc ctttattcac tgacaattcc ttgtcttgat ttttaaagaa ctgacgaatt
     2701 ttgttgcgag ccttattggt tttgaccagt tttacccagt ctcgactagg gccaaaggaa
     2761 ttggcattgg tgatgatttc aaccacatct cctgttttta acttggcagt gagaggaacc
     2821 atacgtccat tgactttggc acctgttgct ttttcaccga tttgcgtatg gatcgcataa
     2881 gcaaaatcaa taggacctga ttcttttggt aactcctgaa cggcccctgt cggtgtaaag
     2941 acataaatcc gttcagaaaa aatgtcttct ttgaccgaat ccacaaagtc cactgcatcg
     3001 ccatttgagg catcttgcaa ttctaccagc tctttgatcc agttcatgcc aacggcttgc
     3061 tcagcttgat tgaccttacc acgcacgcct tttttataag cccagtgagc agcaaccccg
     3121 tactcagcca cttgatgcat gtccttagtt ctgatttgaa tctcaatagg tccttttggc
     3181 ccatacacgg tggtatgaat agactggtag ccattagctt taggagctgc aatataatcc
     3241 ttgaagcggc ctggcatggg acgccaaagc tcatgaatat agccaaccat agcatagaca
     3301 tcgctttgcg tttccatgac acaacgaatg gcaatcagat caaaaatctg atcgaatcgt
     3361 ttctttttgt cccgcatttt ccgataaatc gaataaatgt gttttggtcg gccatacaca
     3421 tctccaaaca acccttgttg tgtcgtatag gttttgacct tactgacaat agcctctacc
     3481 aaagcttcac gctcgcgacg tttttctttc atcatatggg aaattttgta aaattcggtt
     3541 tcattgaggt aacgaaaagc caaatcttct agttcccatt tgatgcgact aatccccaaa
     3601 cgatgcgcca agggggcata gatttccatg gtttcgcgcg aaatgcgctc ttgtttgtcc
     3661 ttgcgcaaat gtttgagggt gcgcatatta tgcaggcggt cagccaattt caccaaaatc
     3721 acgcgaatat ctttggacat agccatcagc attttgcgat ggttttcggc gagttgctcc
     3781 tcatgagatt tgtactcaac tttacctaac ttggtgacac catcaacgat atcacgagca
     3841 tcatggccaa agtctgcttc gatctcatct aaggtaatat ccgtatcttc tacgacatca
     3901 tgtaaaaagc cacaagcaac tgtcacagca tccagatgca aatcagccag aatccccgcc
     3961 acctgaatcg gatggacgat atagggttcg cctgactttc tcacttggta gaaatgggcc
     4021 gctgttgcat atgctaaagc ctttgccaca aaagccacat cagccttggt catataggtg
     4081 gccgctaagg caatgacttc ttctcctgtt acgttcatta tttttgccat ttcgttcctc
     4141 atctagcatt tcttttccct attttaacac tttacacaca aaagcaaaag gcagaatctg
     4201 ctaagaaagc gcttagtgtg accttttctt agaaaacggt tagtgagctg cttttgatat
     4261 cttttgggat ctctcaggcg tgagcatgat accaaaggcc tgctcccgac caaaaataga
     4321 gagaaccaag gggctctctc tattatgttt gcttatcagt aaggtctctc aattcagaga
     4381 attagttgtt ttctttgcgt tttgtaacgg ctaggacacc agctgttgtc atcactgcta
     4441 ctgctgctgc tgtaaagaat gggttggctt gctcaccagt tgctggtaga cgtctgtggt
     4501 tgttggctac aggtgtctta gccatattgc cattgcggcg ttctggcgtt tggttagctt
     4561 ctttgtcagc aggtttttct gcagctggag ttacctcttt gctcttttct ggagcttttt
     4621 cgcctggttg gcctgcttcg ccttctgggc tcttttctgg agctttttcg cctggttggc
     4681 ctgcttcacc ttgtgggcct gctgggcctt gctcacctgg tttgcctgcc tcaccttgtg
     4741 ggcctgctgg gccttgggcg cccgtttcac ctttttcacc ttgtgggcct actggaccct
     4801 gagctccggt ttcaccgcgg tcaccttttt cacccttttc gcctggagct ccatctttac
     4861 ctggagcgcc atctttacca gcttcacctt gtgggccttg gattccagct tcgccttttt
     4921 caccgcgttc accggtttca cctttgtcgc ctttttcacc gcgctcacct ttttcaccag
     4981 ctttaccttg gattccttgc tcaccgcggt cacctttagg accttgggcg cccctctcac
     5041 cagttttacc ttgtggtccg gctgggccag caggaccagt ctcaccacgg tctcccttga
     5101 ttccagattt accaattaaa tctagaatct ccttaagcct cttctcagta aaatctttta
     5161 gctccttttg aaaatcttct tctttaaaat aggttccata ccactttctt tcccaaaatt
     5221 tctcattgga cacttctgga tattttttaa gactttcttc gatctctttt atttttgact
     5281 ctctttgact cgacgtcata gtcgtagaag aaacctcagc cttaacgctg cttgccccgc
     5341 ctccaaaggc tagaaggacg gcagcggctg aggttagccc gtagcgccag actagtttgt
     5401 tgagattatg gtgctttgat gtcaacatat gttgttctct ctttctttat tagatggtgt
     5461 gttttagata aaaataacat ggtagctaga cctgattatt tataatagta ttataataga
     5521 gtgtgaaaac gattgtaaag ttctcttttg ttgttcatct tttagatttt gactgatcac
     5581 tcttttgtgg agatcagagg gctactttgg cacttgcctg cctcgttttt aagtcgaggg
     5641 catccggatc ctttctttaa ggtcactctt ttttgaaatg ttactttttt tgactgcttg
     5701 taccttcttg tctggttgga taccgctagg tttcttcttt acttgtttgt tggtcttgat
     5761 tgtggtaagc ttatgaagaa accttgtagg ataaaaaaag gagacactta tgcctcagat
     5821 tacccttgtt tttattagcc tcagtggcaa cacccttagc tttgtcaagc ggctatccct
     5881 ttatctagca gacaattacg attaccatgt caaacagatt aacattaaag atttgaagca
     5941 cgagactttt cccgtcaagg aagagtttgt ggcgatttta cccacttatc tagaaggcgg
     6001 aaatggcgtt gactctggtg atgtggagat cctcaccact cctttgggag agtttattgc
     6061 tgcccatggc aacgcccagc gttgtcttgg gattattggc tcaggcaaca aaaactttaa
     6121 ccatcagtat tgcctgacag ccaaacagta tgccaaacgc tttggctttc cactgctagg
     6181 tgattttgag ctgcgaggga ctcctgatga catttcgcgg ttagcccagg tcatcatgga
     6241 ggccagctcc agacactcgt ctaacgacac acagacactg cctaacagct agacagtcca
     6301 tagatgatca tagctgtttt aaaaaagagc gcttttagga caataactac agagggccct
     6361 accccacgcc ttgtgatttc tcagcctttg aaaagagcga tcacagtgct tcttggggct
     6421 tgggatcaca ccaagcactc ctagaaatac ccccatgcag actttagcaa ggcaactgaa
     6481 cgcttggtgg tactttctgt gaagctcaga tggttggtga caaaaaagcc ctggttttct
     6541 ggggttactg acatgactaa agaggtctaa ccagctctac cttgagctgg ttagacctct
     6601 ttgtgttctc ctaatccccc ctagatgatc gcagtttctt atgtgtcttg gcttctctta
     6661 tgtggtgtgc ctgttagcac atgctctaac gccagcctaa tgtcacttct agaccatagt
     6721 ggtcactgac gactggcgca tctccgcctt caaaggtaat cttagaagat cggatgatga
     6781 agtccttact ggtaaagaca tggtccacct tgagggcttc tttgttacct tgccagccat
     6841 caatatcagc cacgatgcta tgatcaccaa acacgtggtc agcaccctta tggctatctt
     6901 gtaggtctag ggggctaccc atcatcactt gataaccgtc ttgatccgtt ggattgttaa
     6961 aatctcccat aagtagcaag ggacagttta gtgtgagcag ttctttttct aatttctccc
     7021 actcccctaa aaaccccttg tcaaaccaag ataggtgcac attgacaaca gcgacttctt
     7081 tgccatctaa cgtggttttg gctatgagtg agcgtctggt gtggtagtct gtttcatcat
     7141 ccatcgctga cacgagaata tctgaaacat gaataggttg ttttgataag attgccacgc
     7201 cttcctggta aatgtcatag ccaatatggt tataagccca agaccaataa tagtgctgcc
     7261 ctcgtttttg taaataatgg atcaagagaa gggcaaaatg gtctttatga atgcttggtg
     7321 tccctgaaag agcttgatat cttggtaaat ctgtggccag ctcgctctcg attaactgat
     7381 tgatttcttg caagcaaatg atatcgtatt tttcagctaa aatatgctca gccaaagcaa
     7441 ctaatttttt aagagtgttg gcttgcatcc acgaatgggt attcagtgtt aataccttgg
     7501 tcattaatcc tcctttataa gacaagaaga gccatagggc ctaaaccagc tatggctatt
     7561 acctatcact atctcgtgat gttttgttaa agttctacgg tagctacttt agtcttagca
     7621 ggctgagctc ctaaagatgt caaggtcaca tcttggatct ctgttgtgtt ggtaaaagca
     7681 acaacaatga ttgtttcacg ctctgctgat ttaatagcag caagatctgc tacgactaat
     7741 aggtcacctg catgaacccg ttgcccttct gagactttga ctgaaaaagg cacaccattt
     7801 aaggcgacgg tatcaagtcc cacgtgcacc agcacttcaa gaccattatc tgtcagtaaa
     7861 ccaaaggcat gcttggtcgg aaagacactg gtcacaaggc cagctacggg tgcatagata
     7921 ttaccatggg ttggttcaac cgcaaaccca tctcccatca tcttagccgc aaacacctgg
     7981 tcttttacac ctgtgattgg gagaaccatc ccgtctgcca ctgatagcac atcttctgtc
     8041 acgtgtttaa aatcttttgc gggagtcggt ttgctagtga gctgtgacat attgacttct
     8101 ggaataagag cacctgagtc cagcaaatct tgaatatctg atttcaaaat atctgcttta
     8161 gggccataga ccgcttgaac gccgttgcct ttttggatca agcctatagc gccagctttt
     8221 ttccaatcgt cctcagcacc aaccttagcg gggtctttga ccgtcactcg taagcgcgtc
     8281 atacaagcat caacatcatc aatattgcct gccccaccaa ggagattaac gatttgcacg
     8341 acttgagagt tgctatctgc tacttgggta ggtcttgttt gagtgttacg gtcacccagt
     8401 atatcggcat cgtagttgcc taaacggcca gctgttgcga gatgcatttt cttgatcatc
     8461 atatctgcaa taaagtacat gataactgca aagaggacag aaacccaaac aaagttaatc
     8521 acatccatgc ctaggcctgc tttaagagcc ataggggtgc gggttagtag ctctatattt
     8581 ccaaatgagt gaacacggag attcacaagg tctgccatgg caaatgaagc tccttgaaca
     8641 agggcataga cgatgtaaag tggcattgct gcaaacataa ataggtactc aagtggctca
     8701 gttacccctg tcaaaaagac cgctgccgct gctgagatga acatcatttt gtatgtgtgt
     8761 tttttatcgg catccacatt acggtacatg gctaaggcaa cccccatcaa tgttccggta
     8821 gctccaatca tttgtcctac tttgaaacga gctggagtca cactatccat taagtgacta
     8881 taggctgaag cgtctgatcc tttaaggtga acaaggtcag ttacccaagc aagccacaaa
     8941 gggtcttgac caaatacttt tgtccccgct gctgcacctg tcatgacctc ataagttcca
     9001 ccaagagctg tatagttcat tgggatcgtc aacatgtggt gaagaccaaa tggcaacaag
     9061 agacgttcca aggtaccata taggaatggg gctaggattg gagctgaatc ttgtgaagag
     9121 gcaatccaca tcccaaaact gttaatccca gactggatca ccggccaaac aacaaccaaa
     9181 ataagggcta caaaaataga acgtaaaata acgacaaatg gtacaaaacg cttcccatta
     9241 aagaaggtca aaacttcagg aagtttacgg taattatagt atttgttata ggccgttgct
     9301 cctacgaacc ctgcaataat cccaacaaaa acccctgtgt ttaaagctgg agattccaag
     9361 acactggtga aataatcttt aacgatcatt tgagtgccaa ggaggcttgt gatttttgct
     9421 tctggatcag ctagcatagt actagacacg ccataaaaag cacctgttat ccgattgatc
     9481 aagacaaaag caagccctga ggcaaaggcc cctccagctc tttctttagc ccaactacca
     9541 ccaatggcca aggcaaatag caagtgaagg ttaacaataa cagcccaacc aatttgagcg
     9601 ataatgttgc ctagagatgc caaaaatgct gagtcgtggt taatcattgg aatagagttt
     9661 ccgatactga tcattaaacc agccgctggc atgacagcaa taacgaccat aagacatttc
     9721 ccaaattttt gccaaaattc gaaacgaaac agttgcttga atgatgtttt cattctatct
     9781 ctcctttatt atcccctttt agccatagct gcccttaagg cgcttttgtg acacaatgat
     9841 atagacagca actcagtgat gcaatcgctt gcattgatct gataccttta ttatactagc
     9901 ctcgcaacaa tttgtaaagc gttttcttag acagatgtta gtcgtttttt tcattaatat
     9961 agtagtataa ctcaccaaaa agaggacaag agcccatttc cttttttggt gatgagccca
    10021 tcaacgctct tcgaaaaaac aagaagcaat aaaaaaaggc cgttgacaca atcgtgaact
    10081 gcctgtccgt ttctttagcc tcttctttct aaagtaagca acagcttact tattttgatg
    10141 cctgcaattc caaagcataa ctaagagcac ttaaggcata tagcggcgct gtctctgctc
    10201 gcataatgcg agggcctaag cccaccttaa tggcacttgc tgcctcaaac tgagtgattt
    10261 cagttgggga aattccccct tctggtccaa agataaagag gatttttgcc cctggcttaa
    10321 cttcttttac ttcacgcgcc aaggtcgcta gctgacctgc cttagctgtt tcctcataag
    10381 caatgaagat atgatcaaag ctagaaaggc tttttagaaa ctctgcttta tgttcaaaaa
    10441 ggtgaacttc aggcacccta tttcgtttgc tctgctcagc cgctcctaat acaatcttag
    10501 ccaatttgtc ttctttttta gctaattttt tgccatccca tttgaccact gaccagtctg
    10561 ctgggtagcc ccatagcgca ctggctccca attcagtcac tttctgggca atcgtgtcta
    10621 acttatcgcc tttaggaaat ccagaagcaa tagtcacttt aacaggcaat tccacctgat
    10681 ctggcaaagc ctctataatc tctaactcat gagccatact attggtcacc ttagctaaat
    10741 acttcacccc atcatcaaag accaagacaa cttcagcctc gtcagccaag cgcatcactt
    10801 gaaacatgtg cttgatggta tctttatcgg taatcgttac ctttttttct gctttgcctt
    10861 taataaaata ctgttgcatt agccgccaat cactcctgag atatcatctg tttttttaaa
    10921 gacaagggca ttccactcac cttgaaccat gtgagtttct aagaaaaagc ctgcgctaaa
    10981 ggcagcttcc agaaccatat ccaatttctc agaaatgatg ccagataaga taaggtaacc
    11041 ttcctttttg accaaacggt aagcatcatc agtcaataag actaagatat ccgccaagat
    11101 attggctaca atcacatccg cttcttggct aacccctttt aaaaggtcac cagcagccac
    11161 atgaatgttg tctgttcctt ggtttaaatc aatgttgtct tgagccactc gaacagccac
    11221 gtcatctaag tcataagcgt agatggtttt agcacctagt aaggaactgg caatcgagag
    11281 gacacctgaa ccggtcccta catcgataac tgtctcacca ccacgaagga tttgttccaa
    11341 ggcaaaaagg ctcatcttag ttgtgggatg tgtccctgtc ccaaatgcca ttccaggatc
    11401 tagtttaatc actttttccc cagcagaagc gtcataatcc gtccaactag ggacaatggt
    11461 taaatcatgc gtgatgcgag ctggttcata gtattttttc caattgtctg cccagtcttc
    11521 ctcagccaat tcttgactgt ccacagtaac ctgaccaacc tgtaacccaa aactagctaa
    11581 ctccgctaac tgttcattaa tggtcgcaat aatatccgcc aaattagtac tacttgggta
    11641 ataggctgtg atagctatca tgtcagactg ctccacatct gggtataact ccccaaagcg
    11701 gtccttttgc ccaatatagt ctgcgctatc tgcgatagca accccttgac tgcctgtctc
    11761 aatcaacaca tgtgaaacag cctcttgcgc atcacgatgc acatgaaccg tcacttcttg
    11821 ccacgtttcc atagttatgt cctttctatt ttgacctttt ggttattgtc ctaatagtgt
    11881 tagcaccatc tcatgtgtca ccttagtacc ttgggtaagg gtaacttgct gcttcttcta
    11941 gtccttgttg accttcttca aaagcttgcg cgttccactc caagaagaaa tcagccttgc
    12001 tgtcatctgc taagaaatcc atcaaatcgc tgtgcccttc aatagcaaca tcgttgagaa
    12061 attgcgcaaa gtaagctaag aattcacgag aaaagccctt tttagcgtca aaaggaatag
    12121 taaccaaata atctgctgca tcaaattgag acttggcagg gttataaaag agcacatagt
    12181 cctcaaagac aatatcatct tgggtcactt cgccactatc gtcaatggtt tttatagcct
    12241 ctttattttg agcttctaac acaaaagtca cttcaaccgc atgatttttc ttgtcccaat
    12301 ccatagcata gtcatactga aaatgcttat ccatttcttc ttctaatact gataaaaagc
    12361 cgtatgttgc catctttttt atacctaatc tttctaactg ttgctgtata aggctttgta
    12421 agacctcatt agtttactta ctttgacatg ctgagcgtac tgttataact tttattaact
    12481 gaattataac atatttgact aatattgacc ataagagaag gtcttaatgg caggatcacc
    12541 tctagcaacc gcttttatga tataatttgg gtatgcatag aaaaactatt attgatttca
    12601 aagagctcgg gcaacgctat ctttttgatg agccattagt agaattggta gccaagtcct
    12661 tagatcaggt cggtccagtc attgaaaaag tacaacacta ccaacagctg ggctattacg
    12721 tggtgggcta tctcagttat gaagcagctg ctttttttga caatgcccta caaacccata
    12781 atgacagact aggcaacgag taccttgcct attttacagt gcacaaaacc tgtcaaaaaa
    12841 aagacctacc tcttgattat gacagcatta ctatccctaa ccaatgggtc agcgcaactc
    12901 aaaaagaagc ctatcaaaaa gccattgaaa ccattcaccg tgagatgcaa cagggcaata
    12961 cttatcaggt taactacacc cttcaattaa ctcaggaact caatgcagct gatagtttag
    13021 ccatttacaa taaactcgtc gttgaacagg ctgctggcta caatgcctac atcgcccatg
    13081 atgagtttgc cgttatttca gctagtcctg aattgttctt taaacaagag ggcaacaggt
    13141 taactactag gcctatgaaa ggcaccacca aacgaggggt taatagctgg ctggatcaac
    13201 aagaacatga ctggctccaa gctgacggga aaaaccgttc tgaaaacatg atgattgtgg
    13261 atttgctccg caatgacatg gggaaaattt gccaaacagg cagtgttcgt gttgataggc
    13321 tctgtgaggt cgagcgatac tctaccgtct ggcaaatgac ctcaactatt gttggtgacc
    13381 tcaaagcgga ctgtgacctg atagacattc tcaaagctct ctttccttgt ggctctatca
    13441 caggggcacc aaaagtctcc accatggcaa ttatcacatc tctggagcca aaaccaaggg
    13501 ggatttattg tggaagtatt ggcatttgcc tacctgatgg tcgccgtttc ttcaatgttc
    13561 ccattagaac catccagctc agtcataatc aagctactta tggtgtcgga ggcggcatca
    13621 cttggcaaag caagtgggaa gacgaatacg aggaagtcca tcaaaaaaca gcttttctct
    13681 atcggcacaa acaaatcttt gacctcaaaa caaccgccaa ggtggaacac aaaaaaatag
    13741 ccttccttga gcaacacctc aatcgcctta aagaagcagc cacttatttt gcttaccctt
    13801 ataatgaaaa agctttgcag aaacaactgt caacctattt ggaaaataag aataatgctg
    13861 cctaccgttt gatgattcgt ttatccaaag atggaaagat tagcctctct gatcaaccct
    13921 tggaaccttt gtcagccgat tttctgacag ctcaactctc tttacagaaa aaggacgtga
    13981 cagcttcgcc ttttacctac tttaagacca gctaccggcc tcatattgag caaaaatctt
    14041 atgaacagct attctataac caagcggggc aattattgga aacgtccatt ggcaatctct
    14101 ttgttcagct gggtcagacc ctctacacac caccagtggc tgtggggatt ttaccaggac
    14161 tttttcgcca agaactgcta gctactggtc aagctcagga aaaagaggtg acactagctg
    14221 atttaaaaga ggctagcgct atttttggag gaaatgctgt ccgtggcctt tatcctctca
    14281 accttgagct tactcacctt gatgccctct tagctaagag tcaagcctaa actgccactc
    14341 atcttttgtt attaaggaac ctatgatact cttaattgat aattacgatt catttaccta
    14401 caacctcgcc caatatttaa gtgaatttga cgagacgatt gtcttgtata accaagaccc
    14461 aaacttatat gacatggcca aaaaagctaa cgctctagtc ctctcacctg gtcctggttg
    14521 gcccaaggaa gccaaccaaa tgccaaaact cattcaagac ttttaccaaa caaaacctat
    14581 cttaggagtg tgtctgggac accaagctat cgctgaaact ttagggggaa ccttacgctt
    14641 ggccaaacgc gtcatgcatg ggagacaaag caccattgaa acgcaaggcc ctgctagtct
    14701 ttttcgctcc ctgccacaag agatcaccgt catgcgctac cattccatcg ttgtggatca
    14761 gttaccaaaa ggttttagcg taaccgctag agactgtgac gatcaagaaa tcatggcatt
    14821 tgaacaccac accctgccac tttttgggct acaatttcac ccagaaagca tcggaactcc
    14881 tgatggcatg accatgattg ccaacttcat cgcagccatt ccccgttaat ctcatccccc
    14941 aaaagaaagg aggacagtta catgcctgat catttagcgc tcagaatgcg ccccaaaacc
    15001 atttcagagg tcatcggaca aaaacacctt gttggcgaag gcaaaatcat ccgtcgcatg
    15061 gtggaagcaa atagactatc gtccatgatc ctctatggcc ctccaggaat cggtaaaact
    15121 tccattgctt ctgctattgc tggtactact agatatgcct ttcggacctt taatgccacc
    15181 attgacagca aaaaacgtct ccaagaaatt gcggaagaag ctaaattttc tggtggcttg
    15241 gtattattac tagacgagat tcatcgcctt gacaagacaa aacaagattt tcttttacct
    15301 ttacttgaga atggcaccat tatcatgatt ggcgcaacca ctgagaaccc cttcttttca
    15361 gtgacacccg ctatcagaag cagggtccaa atttttgaat tggaaccact ttctaacgag
    15421 gatattaaaa cagccattca gctagcaatt tccgacaaag aacggggatt tcctttttta
    15481 gtgacaattg atgatgaggc gctagatttc attgttaccg ccacaaatgg agacctacga
    15541 tctgcttata attccttgga tctagcagtc atgtctactt ctcctaatga agatggtagt
    15601 cgtcatatta gtctagagac aatggaaaat agtctgcagc gtagttatat taccatggat
    15661 aaaaacgggg acgggcatta tgatgtttta tctgccttac aaaaatccat tagaggttct
    15721 gatgtcaatg ctagcctgca ctatgccgct cgtttagtag aagctggaga cttgcctagt
    15781 ttagcaagac gattgaccat tattgcttac gaagatattg gcttagccaa ccctgacgcc
    15841 caagttcata ccgtcaccgc actagatgcc gcccaacgca ttggttttcc agaagctcgt
    15901 attcttatcg ctaacgtggt cattgatttg gctctatcac ctaaatccaa ttcagcttat
    15961 ttagctatgg atgcagcttt agctgatttg agaacatcag gcaacctccc cattccaaga
    16021 catcttagag acgggcatta tgctggcagc aaggacctag gcaatgccaa agattacctc
    16081 tacccacacg cctaccctga aaaatgggtc aaacaacaat acctaccaga taaattagta
    16141 ggacatcatt attttgaagc caatgaaacc ggtaaatacg aacgcgcact tggttcaaat
    16201 aaagagcgta ttgataagct ctcagactga ctgctagttt taaaaatcgc aaccgatttc
    16261 aaaaatcgat aattttgctt gaaaaaattt taaaaagtgg tattataaaa gtacagaaac
    16321 attgctgtgg catacgaatc cacatctaag tgttgaccga ctatttcttt gtattttcgg
    16381 gaaacaaaga ctctttctag tctgcaagcc gtttcacgcg gacgcaactt ccaagaaaga
    16441 gcgcgttacc cacctgctta tactgcgcgg gctcaataca aaaacgtgga tcaccggtgc
    16501 caatacagca ttcttgcctc cttagctcag ttggtagagc agtagactct taatctatgg
    16561 gtcacaggtt cgagccctgt agggggtata aactatacat gaaaaaacct ttgtttaaag
    16621 gctttttttg cttgtcagaa gaggatttgt tccatcattt atccccgcag taatttttta
    16681 tggtatgata ccaattaaag cgcttaagat taaggtggag actgttatga aaataattga
    16741 gtacaaagga aattacagag atgacctcat ttttatggtc ttggaagcaa aaaatgcctt
    16801 aaggagaatt cccagcatta acccggatct tttgacaatt gaaacaagtt atttggaaaa
    16861 agaggattgt ttttggctag cggtcaatga agaaagtcgt gttattggct caatcgctta
    16921 ttcttctatt cccaaaacaa atgaggtctt cttgcaccgt ctcttcatca aaccaagctt
    16981 aaaacatcaa ggcattggca gtcaacttct ggcgtttgca gaagattatc taaggaaaat
    17041 cggcaagagt catgttcgta tccacttagg tcaacctaaa gaacaatggt ttgaatctta
    17101 tcggttttat cctaaacatg gttatcaatt ctatgatgac acgcatctca tcaagaaact
    17161 aatctaaaca catttcctac cctttatagt catttcatac gtcattttta ggaggtatcc
    17221 attgaaaatt gccatcattg gacatagtgg ctctggcaag tcaaccttag cacgattttt
    17281 aggccaacat taccattgtg aggtattcca tttagaccaa ctacacttct catcgaactg
    17341 gcaagaacgg tcagatcatg acatgatagc tgatttatca acatgcctgc tcaaacaaga
    17401 tttgattatt gaggggaatt atgccaattg tctctatgaa gagcgcatga gtgaagctga
    17461 ttacattatc tatgttaatt tcagtcggtt tcattgtgtc tatcgagcat ttaagcgtta
    17521 tttaaactat aggggaaaaa cgcgtcctga tatggctgac aactgtcagg aaaaatttga
    17581 cgttgcgttt gtgaaatgga ttctactaga tggacgttca agaaaccaat taaaaaaata
    17641 ccaatccgtt gtccaaaaat actctcataa aaccattgtc ttaacaaatc aaaagcagct
    17701 aagtcattat atgaatacga tcaactaatt agagtgcaaa actaaaataa ccacgggtaa
    17761 tccgggctat tcagactgaa agcctttgtt taaaggcttt tttgcttgtt tcataactaa
    17821 tcggcttaat taaaagcgtc aatccacttt tagtatcatg tctcaatttt cattcgatag
    17881 tcagcaagta tatctacaaa attgttaatg attatttctt ttgaaagtgt tatattaaaa
    17941 cataataaaa taataactcc tgaaaagagg ctatttatga aaaaaacaaa acttattttt
    18001 tcttttactt caatattcat tgcaataatt tctcgtcctg tgtttggatt agaagtagat
    18061 aataattccc ttctaaggaa tatctatagt acgattgtat atgaatattc agatacagta
    18121 attgatttta aaaccagtca taacttagtg actaagaaac ttgatgttag agatgctaga
    18181 gattttttta ttaactccga aatggatgaa tatgcagcca atgattttaa agatggagat
    18241 aaaatagcta tgttctccgt cccatttgat tggaactact tgtcagaagg aaaagtcata
    18301 gcatatacct atggtggaat gacgccttat caagaagaac caatgtctaa aaatatccct
    18361 gttaatttat ggattaatag aaagcagatt cctgtcccct ataatcaaat atcaactaac
    18421 aaaacaacag ttacagctca agaaattgat ctaaaggtta gaaaattttt aatatcacaa
    18481 catcaattat attcttctgg ttctagctac aaaagtggta aattagtttt tcatacaaat
    18541 gataattcag ataaatattc tctcgatctt ttctatgtag gatatagaga taaagaaagt
    18601 attt
//
LOCUS       DAUGJR010000039        16314 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUGJR010000039 DAUGJR010000000
VERSION     DAUGJR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16314
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.039"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            580..3606
                     /locus_tag="VH800_001407"
     CDS             580..3606
                     /locus_tag="VH800_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEQ8362471.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPSGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTLGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STIVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            3626..4027
                     /locus_tag="VH800_001408"
     CDS             3626..4027
                     /locus_tag="VH800_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEQ8362472.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(4207..5082)
                     /locus_tag="VH800_001409"
     CDS             complement(4207..5082)
                     /locus_tag="VH800_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEQ8362473.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCTLHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIEVN"
     gene            5218..5739
                     /locus_tag="VH800_001410"
     CDS             5218..5739
                     /locus_tag="VH800_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8362474.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            5954..6472
                     /gene="rimM"
                     /locus_tag="VH800_001411"
     CDS             5954..6472
                     /gene="rimM"
                     /locus_tag="VH800_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEQ8362475.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DRFVQEVTIVSHRKQKHFDIIKFKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYH
                     QIIGMAVYEKDVLIGHVKEILQPGANDVWIVKRPGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            6462..7193
                     /gene="trmD"
                     /locus_tag="VH800_001412"
     CDS             6462..7193
                     /gene="trmD"
                     /locus_tag="VH800_001412"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEQ8362476.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLKKTYLRRPDLL
                     EHYNFSEEERKLLDKIKEALDQGED"
     gene            7193..8185
                     /locus_tag="VH800_001413"
     CDS             7193..8185
                     /locus_tag="VH800_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8362477.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            8363..9421
                     /locus_tag="VH800_001414"
     CDS             8363..9421
                     /locus_tag="VH800_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEQ8362478.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            9434..10357
                     /locus_tag="VH800_001415"
     CDS             9434..10357
                     /locus_tag="VH800_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEQ8362479.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     VVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQV
                     ADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            10613..11326
                     /locus_tag="VH800_001416"
     CDS             10613..11326
                     /locus_tag="VH800_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8362480.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            11323..12234
                     /gene="pfkB"
                     /locus_tag="VH800_001417"
     CDS             11323..12234
                     /gene="pfkB"
                     /locus_tag="VH800_001417"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEQ8362481.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISQEQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            12231..14177
                     /locus_tag="VH800_001418"
     CDS             12231..14177
                     /locus_tag="VH800_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8362482.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            14270..14869
                     /locus_tag="VH800_001419"
     CDS             14270..14869
                     /locus_tag="VH800_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8362483.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            15021..15728
                     /locus_tag="VH800_001420"
     CDS             15021..15728
                     /locus_tag="VH800_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8362484.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(15785..16120)
                     /locus_tag="VH800_001421"
                     /pseudo
     CDS             complement(15785..16120)
                     /locus_tag="VH800_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         5275 a         2628 c         3347 g         5064 t
ORIGIN      
        1 ttatattctt tacattctga tgaaaataca aattatccta acatgatgta ttgaaagggg
       61 aaatagttta tgttagtata ctgattaagt gaagctgtaa tgaggcttat acgatcaaaa
      121 aagttagagt aactttataa aacagtggtg ttgaagcaag tttagcttct tctcagaaat
      181 agattatcta taaaaaatcc caaaagtagt ttgtttccag ttaatgaact tcttttggga
      241 aggctttttt gctgatcgcc acttcacttg tatatcggga acattcacgc taagatgtat
      301 aagttgaatc gtttgtctat ggcttgatga aaattaatca aaagataatg ttcaactcta
      361 taattagtac aagcaaaatg agatagctta ttcattagta agcataagat ataacaagag
      421 aaattacctt aaaacaggaa gtactagagt atttaaaata agtgatagac ttggatatta
      481 ttaggtcgac tagtgttctt ttcaataatt taatatcgtt attattagta tcagccaatc
      541 aaatgtggat aagttggctt ttagaaaggt tttaccacaa tgaagaaaca tcttaaaaca
      601 gttgccttga ccctcactac agtatcggta gtcacccaca atcaggaagt ttttagttta
      661 gtcaaagagc caattcttaa acaaactcaa gcttcttcat cgatttctgg cgctgactac
      721 gcagaaagta gcggtaaaag caagttaaag attaatgaaa cttctggccc tgttgatgat
      781 acagtcactg acttattttc ggataaacgt actactcctg aaaaaataaa agataatctt
      841 gctaaaggtc cgagagaaca agagttaaag gcagtaacag agaatacaga atcagaaaag
      901 cagatcactt ctggatctca actagaacaa tcaaaagagt ctctttcttt aaataaaaca
      961 gtgccatcaa cgtctaattg ggagatttgt gattttatta ctaaggggaa tacccttgtt
     1021 ggtctttcaa aatcaggtgt tgaaaagtta tctcaaactg atcatctcgt attgcctagt
     1081 caagcagcag atggaactca attgatacaa gtagctagtt ttgcttttac tccagataaa
     1141 aagacggcaa ttgcagaata taccagtagg gctggagaaa atggggaaat aagccaacta
     1201 gatgtggatg gaaaagaaat tattaacgaa ggtgaggttt ttaattctta tctactaaag
     1261 aaggtaacaa tcccaactgg ttataaacat attggtcaag atgcttttgt ggacaataag
     1321 aatattgctg aggttaatct tcctgaaagc ctcgagacta tttctgacta tgcttttgct
     1381 cacctagctt tgaaacagat cgatttgcca gataatttaa aagcgattgg agaattagct
     1441 ttttttgata atcaaattac aggtaaactt tctttgccac gtcagttaat gcgattagca
     1501 gaacgtgctt ttaaatcaaa ccatatcaaa acaattgagt ttagaggaaa tagtctaaaa
     1561 gtgatagggg aagctagttt tcaagataat gatctgagtc aactaatgct acctgacggt
     1621 cttgaaaaaa tagaatcaga agcttttaca ggaaatccag gagatgatca ctacaataac
     1681 cgtgttgttt tgtggacaaa atctggaaaa aatccttctg gtcttgctac tgaaaatacc
     1741 tatgttaatc ctgataagtc actatggcag gaaagtcctg agattgatta tactaaatgg
     1801 ttagaggaag attttaccta tcaaaaaaat agtgttacag gtttttcaaa taaaggctta
     1861 caaaaagtaa aacgtaataa aaacttagaa attccaaaac agcacaatgg tgttactatt
     1921 actgaaattg gtgataatgc ttttcgcaat gttgattttc aaaataaaac tttacgtaaa
     1981 tatgatttgg aagaagtaaa gcttccctca actattcgga aaataggtgc ttttgctttt
     2041 caatctaata acttgaaatc ttttgaagca agtgacgatt tagaagagat taaagaggga
     2101 gcctttatga ataatcgtat tgaaaccttg gaattaaaag ataaattagt tactattggt
     2161 gatgcggctt tccatattaa tcatatttat gccattgttc ttccagaatc tgtacaagaa
     2221 atagggcgtt cagcatttcg gcaaaatggt gcaaataatc ttatttttat gggaagtaag
     2281 gttaagacct taggtgagat ggcattttta tcaaatagac ttgaacatct ggatctttct
     2341 gagcaaaaac agttaacaga gattcctgtt caagcctttt cagacaatgc cttgaaagaa
     2401 gtattattac cagcatcact gaaaacgatt cgagaagaag ccttcaaaaa gaatcattta
     2461 aaacaactgg aagtggcatc tgccttgtcc catattgctt ttaatgcttt agatgataat
     2521 gatggtgatg aacaatttga taataaagtg gttgttaaaa cgcatcataa ttcctacgca
     2581 ctagcagatg gtgagcattt tatcgttgat ccagataagt tatcttctac aatagtagac
     2641 cttgaaaaga ttttaaaact aatcgaaggt ttagattatt ctacattacg tcagactact
     2701 caaactcagt ttagagacat gactactgca ggtaaagcgt tgttgtcaaa atctaacctc
     2761 cgacaaggag aaaaacaaaa attccttcaa gaagcacaat ttttccttgg ccgcgttgat
     2821 ttggataaag ccatagctaa agctgagaag gctttagtga ccaagaaggc aacaaagaat
     2881 ggtcagttgc ttgaaagaag tattaacaaa gcggtattag cttataataa tagcgctatt
     2941 aaaaaagcta atgttaagcg cttggaaaaa gagttagact tgctaacagg attagttgag
     3001 ggaaaaggac cattagcgca agctacaatg gtacaaggag tttatttatt aaagacgcct
     3061 ttgccattgc cagaatatta tatcggattg aacgtttatt ttgacaagtc tggaaaattg
     3121 atttatgcac ttgatatgag tgatactatt ggcgagggac aaaaagacgc ttatggtaat
     3181 cctatattaa atgttgacga ggataatgaa ggttatcatg ccttggcagt tgccacttta
     3241 gctgattatg aggggctcga catcaaaaca attttaaata gtaagcttag tcaattaaca
     3301 tctattcgtc aggtaccgac tgcagcctat catagagccg gtattttcca agctatccaa
     3361 aatgcagcgg cagaagcaga gcagttattg cctaaaccag gtacgcactc tgagaagtca
     3421 agctcaagtg aatctgctaa ctctaaagat agaggattgc aatcaaaccc aaaaacgaat
     3481 agaggacgac actctgcaat attgcctagg acagggtcaa aaggcagctt tgtctatgga
     3541 atcttaggtt acactagcgt tgctttactg tcactaataa ctgctataaa aaagaaaaaa
     3601 tattaaattg atttaaggag aaaaaatgat aacacaagaa atgaaagatc ttattaataa
     3661 ccaattagca atggttgcga cggttgatgc caaaggtcaa cccaatattg gtccaaaacg
     3721 ttctatgcgt ctctgggatg ataaaacatt tatttataat gaaaatacag atggtcaaac
     3781 tcgtattaac attgaagata atgggaaaat tgaaattgcc tttgttgatc gtgagcgcct
     3841 tttaggttac aggtttgtag gaactgctga aattcaaaca gaaggtgctt attacgaagc
     3901 agcgaaaaaa tgggcacaag gacgcatggg ggtaccaaaa gcagttggta ttattcatgt
     3961 cgagcgtatt tttaatttac aatctggtgc taatgcaggt aaagaaataa acagtgaaag
     4021 taactaaaat taactgtaac agtatttagg acccttattt taaacgctaa aaaacaagca
     4081 tactcttttt tacagcatag tgactatgtt gtaaaaaggg gtatgcttat taggtgctct
     4141 taatatttat agataactgc acctaataag ttttcaatag acttatagca cattaattga
     4201 cttcaattag ttgacttcaa tactagaaag agaagaacag tgatgttggt gttcgtttaa
     4261 agaagtatcg atttccacag tgactgagtt tatattgtac ctttgacaaa tcagtctaat
     4321 agattttttg caatgttttt cagtggtaga ttctctcaag cagcaatgta tagttgctct
     4381 atgatcaata ccatccatcg accaaacatt aagctgatta acagacacta tatgaggaag
     4441 ttggctgagt tcatggtgca aagtgcaata gtctatagaa tcaggaacac catctaaaaa
     4501 aatgttagca gttgctacta actttggaag agctttagat aatataaaag aagcaatggc
     4561 aattgataat aaaggatcaa gaatgtacca aggtttccat tttaagatca gtgacagtat
     4621 gataatggct aaccacccaa ggatatcttc taaaaagtga aggcttaata tttcttcatt
     4681 ttttgtctgg ttagagtgaa tgatgaagct agcaaatcca ttgattataa ttgcaaaaat
     4741 agctaaaacg aacataccgt cataattaac aatagtagga tgccataatt ttggtatcgt
     4801 ttcaatcatt actaataatg acccgctaat aagtattaga tttgtcgtta gcgctcctaa
     4861 aaggctaaat cgcttatagc ctagtgaaaa atttggactc tcttttttaa cagcctttct
     4921 ttctaagata gctgagatac caatagcaat ggcatctcca aaatcgtgga cagcatctgc
     4981 taaaatagca cccgaaaaga ataatgtccc aaaaataaat tcaatgaggg aaaaactaag
     5041 atttaatata aaaataatgg tgactttttt acttgctggc ataattttct ccttttgtta
     5101 tactggtaat atgtatagta gaatgcttta ttctattatc taaaagttaa aatacaatta
     5161 ctataaccaa aaatgagcac ctgttcaata gtgaacaaca tttagaaagt gtccgatatg
     5221 acaaaagaca gacaaatcaa aaaaacaaaa acagctatct atagtgcttt tattgcttta
     5281 ttacaaaaaa aagaatattc gaaaataact gttcgagata tgattacact tgctaatgta
     5341 gggagatcaa ccttttatgc acattatgaa agcaaagaaa tgttactaaa agaactctgt
     5401 gaagaacttt ttcatcattt gtttaggcaa aaaagaaatg tgacttttga ggactatttg
     5461 gtacatattt taaagcattt tgaacaaaat aaagacagca ttgcgacgtt gttactttct
     5521 aatgatccct attttttatt aagatttaaa aacgaactag aacatgatgt ttaccctaac
     5581 ttgcgctgca agtatatcga caaaacgact attccagaag tattcctaaa acaatttgtt
     5641 ctatctagtt ttatagaaac cttaaaatgg tggctccatc aaaggcaaag gatgtctgca
     5701 aatgaactat taaagtatta tttagagctc ataaaataat gactagtgag tcatcttgcc
     5761 aaattcaatt ttttaataca gacggatttt aacaatttaa cagataaaga caaaactgta
     5821 agtgcaaaat agactataac gtgataaaat aataggtaat ttggttctga aaaagaagtg
     5881 tctatcaaac tttagaatca agagaggtcg ctaaagtgac gtgagataaa gagttaacga
     5941 tttaggagct accatggaat attttaatgt tggaaaaatt gtcaacacgc aaggcctgca
     6001 aggagagatg cgcgtgttgt ctgtcagtga ttttgctgag gaacgcttta aaaaaggctc
     6061 acaattagct ttatttgatg ataaagatcg gtttgttcaa gaagtgacaa ttgttagtca
     6121 ccgtaaacaa aagcattttg atattatcaa atttaaagac atgtatcata ttaatgctat
     6181 tgaaaagtac aagggataca ctttaaaggt ctcaaaagac aatcaagggg atttacaaga
     6241 aggagaattt tattaccatc agattattgg catggctgtt tatgaaaagg atgtccttat
     6301 tggacatgtt aaggaaatct tgcagccagg tgctaatgat gtttggatag tgaaacgccc
     6361 aggaaaacga gacttgctct taccatatat tcccccagta gttcttaacg tagatgttcc
     6421 taacaagcgc gtggatgttg aattgatgga aggcttagac gatgaagatt gatattttaa
     6481 ccctttttcc tgaaatgttt gcccctctag agcattccat tgtaggcaag gcaaaagaaa
     6541 aaggtctgtt agacattcac taccataact ttcgagatta tgctgaaaaa gctcgtcatg
     6601 tggatgacga accctatggt gggggccaag gcatgttatt gagagcgcag cccatttttg
     6661 acaccattga acagattgaa gccaaaaaac caaggattat tcttttagat ccagcaggta
     6721 aaccctttac tcaggcttat gctgaagaat tagctcttga ggaagagtta atttttattt
     6781 gtggtcatta tgaaggttat gatgagcgga ttaagacctt ggtgacggat gaaatttcat
     6841 taggcgactt tgtattaaca ggaggtgagt tggcggccat gactatggtg gatgcgaccg
     6901 tcaggttaat tccacaggta cttgggaaag aaagtagcca tcaggacgat tctttttcat
     6961 caggactttt agaataccct caatacacaa gaccttatga ttatcgtggt atgacagttc
     7021 cagatgttct aatgagtggt catcacgaac gtattcgctt gtggcgtcta gaagaaagtc
     7081 tcaaaaaaac ttatttaagg cggccagatt tacttgaaca ttacaatttt tccgaggaag
     7141 agcgcaagct attggataag attaaagaag cattggatca aggagaagat tagtgaaaga
     7201 taaagcatat gatattacga ttattggtgg tggtccaata ggtttatttg cagcctttta
     7261 tgcaggtctt aggggcgtaa cagtaaagat tattgagagt ttgtcagaac ttggtggaca
     7321 gcctgccatt ctttatcctg agaaaatgat ttatgatatt ccagcttatc catctttaac
     7381 aggtgttgag ttgacagaaa atttaataaa acaattgagc cgttttgaag atcgtacaac
     7441 catttgttta aaagaagaag tattaacctt tgacaaggtt aaaggtggtt tttcgattag
     7501 gactaataag gcagagcatt tttcaaaagc cattatcatt gcttgtggaa atggcgcttt
     7561 tgcaccaaga actttagggt tagaaagtga ggaaaacttt gctgatcata acctttttta
     7621 taatgttcac cagttggacc agtttgcggg acaaaaagtt gtgatttgtg gtggtggaga
     7681 ttcagcagtt gattgggctt tggctttaga agatattgct gagagtgtga cggttgtgca
     7741 ccgtcgtgat gctttcagag cacatgaaca cagtgtggaa ttattgaaag catcaacggt
     7801 caacctctta acaccttatg tgccaaaagc attgaaagga attggaaacc tggctgaaaa
     7861 attagttatt caaaaagtga aagaagatga agtgttagaa cttgaattgg acagtcttat
     7921 tgttagtttt ggtttttcaa cttctaataa gaatttgaaa aattggaatc tcgactataa
     7981 gcgttcaagt attactgttt caccactttt tcaaacaagt caagaaggta tttttgccat
     8041 tggtgatgca gccgcttata atgggaaagt ggatttgatt gctactggtt ttggcgaagc
     8101 accaacagca gttaatcagg ccattaacta tatttatcca gatcgagata accgtgtggt
     8161 gcattcaacc tctttaattg actaagggag tcggaagttt caagagcagt agcaacagct
     8221 aatattcagt ttgtcaggag aggacaaatg gtttttacct aagtcttcgt gacaagtttt
     8281 atactttgtg ataaaatagt cattgtgaaa aaagtgtgat ggttttcaca gattaacaca
     8341 ttacaatgaa aaggggtcta tcatgacaac aacagataaa gagacattta gttcttttat
     8401 gaataaggtc ttggctggta cagcgattgc tatcgttgtg gcactcattc caaatgctat
     8461 tttagcgact ttcttaaaac cgcttttgcc aaatatggca gctgctgaat ttttacacat
     8521 tgtgcaagtc ttccaattct tcacgccgat tatggctggt ttcttgattg ggcaacaatt
     8581 taagtttaat cctatgcaac agttggctgt tggtggagct gcttatatcg gttctggagc
     8641 ctgggcttat acagaagtca ttcaaaaagg tgtggcgaca ggaacattcc aacttagagg
     8701 tattggggac ttaatcaata tgatgattac agctagcctt gcggttttag ctgtgaaata
     8761 ttttgggaat aaatttggct ctttaaccat tatcttgtta cctatcacta taggaactgg
     8821 cgtaggttat attggttgga aatttttgcc ttatgtgtct tacgtgacaa ccctgatcgg
     8881 acaagggatt aattctttta caaccttaca acctatttta atgtctattt taattgcagt
     8941 tgctttctcg cttatcattg ttagtccgat ttcaactgtt gcaatcggtt tagctattgg
     9001 gcttaatgga atggctgcgg gagcagcttc tatgggaatt gcatcgacag cagcagtctt
     9061 agtgtgggcg acgcttaaag ttaataaatc tggtgtacca attgctatcg cacttggggc
     9121 tatgaaaatg atgatgccaa acttcttgaa acatcctatc atggctattc cgatggtgtt
     9181 cactgcagca attagctcat taacagtacc attgtttaat cttgttggaa caccagcttc
     9241 atctggtttt ggcttagttg gtgcagtagg tccgattgct tctttagcag gtggtagctc
     9301 aatacttatt attatccttg cttggatcat tgttccgttt gcggttgctt ttgcggcgca
     9361 taaggtttct aaagatattc taaaactgta taaagaagac attttcgtct ttgaaggcta
     9421 ataggaggaa aatatgttag tttatattgc tggctcagga gccatggggt gccgttttgg
     9481 ttaccaaatt tcaaaaacaa ataacgatgt gattttgtta gataactggg aagatcatat
     9541 caatgccatt aaagaaaacg gtttagtggt gacaggggat gtggaagaaa cagttaagct
     9601 tcctattatg aaaccgactg aagccactca agaagccgat ttgattatct tgtttacaaa
     9661 agcaatgcag ttgccacaaa tgcttcaaga cattaaaggc attattggaa aagaaaccaa
     9721 agtgctttgc cttttaaatg gtcttggaca cgaagacgtt attcgtcagt acattccaga
     9781 gcacaacatt ttgatggggg tcactgtctg gactgctggt ctagaaggtc ctggtcgtgc
     9841 tcatcttcaa ggtgtgggag cacttaactt acaaagcatg gatccaagca atcaagaagc
     9901 tggacaccaa gtggctgatt tgttaaatga agctaacttg aatgcgactt atgatgagaa
     9961 tgttgtgcca aacatctggc gaaaagcttg cgtgaatggt accatgaact caacttgtgc
    10021 ccttctagat tgtacaattg gtgaattatt tgccagtgaa gacggtctca aaatggtaaa
    10081 agaaatcatc catgagtttg ttatcgttgg tcaagcagaa ggtgtcgaac taaacgaaga
    10141 agaaatcaca caatatgtaa tggatacatc tgttaaagct gctcaccatt acccatcaat
    10201 gcaccaagac cttgtgcaaa atcaccgatt gactgaaatt gattttatca atggtgcagt
    10261 caataccaaa ggtgaaaagc ttggtatcaa tactccatac tgccgtatga ttacagagct
    10321 agttcacgct aaagaagcag tgttgaacat ccaataaacg ctatcaaatc gttatactca
    10381 atattatggc taaagcttta atattgagtt ttttgttatg ctgatagtat ttttcttagg
    10441 cgtcattatt tgtgagccta gattatgagt taataaaaga aataataatt ggtagaattt
    10501 gatagatttt gaaaggttat gcttgacttt tagttataaa atagtataat aattgtaaac
    10561 gatttcagtt aggggtggtt ctatcttaaa atcaaaacga aaacaattaa tcatggcaaa
    10621 gatcactgaa gaaaactatg tttctttaga ggatttaatg caattactca actcctctga
    10681 gtctactatc cgtagagatc taggagagtt ggagcaagaa ggacggctac atcgtgttca
    10741 tggaggtgct gaactttttc actctttaca agaggaactt tcgaaccaag aaaagtctgt
    10801 caaaaacagt catattaaaa aagctattgc gcaaagagcc tctcagctta tctatgacaa
    10861 cgatgtgatc tttattgatg ctgggacaac gactgaattt ttattacctt ttttacaagc
    10921 taaaaattta actgtagtta ctaattctat tcatcatgct gctagattag ttgaactctc
    10981 tattgagacg attattgtag ggggttatgt caaacaaacg accgatgcca gtattggtaa
    11041 cgtagctttg gaacagatta ggcagatgaa ttttgacaag gcatttcttg gaatgaatgg
    11101 tgttgatgat tcttacctga cgactcctga tatggaagaa gcagttatta aaaaagcggt
    11161 tctgtcaaat gcaaaattag cttacatttt agtagatggc actaaaattg gtcaggtatc
    11221 gtttgtaaaa gtagctccta ttaatgatgt gactattatt acattaggag gatcagcaag
    11281 tattcttaaa caaataaagg aaaaggcaaa ggtgattgaa ttatgattta taccgtgacc
    11341 ttaaaccctt ctattgactt tattgtcaga attgaccaaa taaatcttgg gtcagtgaat
    11401 cgcatggcga gtgatgataa gtttgctgga ggtaaaggca ttaatgtgag tcgcatcttg
    11461 caacgtttag acattgctag cacggcgaca gggttcttgg gtggttttac aggacgtttt
    11521 atcgaagaaa gtttgagtgc agaaggcgtt aaaactgatt ttgtaaaagg tgatcaagat
    11581 actcgaatca atgttaaaat caagtcacaa gaagagaccg aattaaatgg tcaaggacct
    11641 atcattagtc aggaacaact ggaggatttg aaaactaagc tttcccagct aacagcagag
    11701 gatacagttg tctttgcagg ttcagcgcca gctaatcttg gcaatgctgt ttataaggaa
    11761 ttacttcctt tagttaggca aagcggtgct caggtggttt gtgattttga aggacagact
    11821 ttaatagatg cgcttgcata taatcctctg ttggttaaac ctaataatca tgaactagaa
    11881 gctatttttg gtacgattct gaccagtctt gatgatgttg aaacctatgc ccgtcgtctt
    11941 ttagagatgg gtgctcaaaa cgtcatcatt tcaatggctg gtgatggtgc tttgctggtt
    12001 actaaagaag cgacttattt tgctaaaccg attaagggag aagttaaaaa ttctgtcggt
    12061 gctggtgatt cgatggttgc tggctttaca ggcgaattta tgaagagtca aaatccaata
    12121 gaagccttaa aatggggcgt ggcttgtggt acagcgacgg ctttctctga tgacttggcg
    12181 acaattgcat ttattaagga aacatatcat aaagttgagg tagaaaaacg atgaaaattc
    12241 aagatttatt gagaaaagat attatgattc tcgatttaca ggctatttct aaagaagttg
    12301 ccattgacga gatgattact aaattagttg aaaaagatat tgtacatgat tttgatgtct
    12361 ttaaaaagag tatcatgaca cgtgaagaac aaacatcaac agggcttggt gatgggattg
    12421 ccatgcctca ttctaaaaat attgtagtag ataaaccagc ggtcttgttt gcgaaatcaa
    12481 ataaaggtgt ggattacaag gctttagatg gtcaaccaac ggatctcttc tttatgattg
    12541 ctgcgcctca aggagcaaat gatactcact tggctgcact agcagaatta tcacaatacc
    12601 ttttgaaaga cggctttgct gataaacttc gtgctgcagc gacaccagaa gcagtcattg
    12661 ctgtttttga tgaagcgtca acagctaaag aagaagtggt tgctccaaca agtggtcaag
    12721 actttatcgt tgctgttaca gcttgtccga caggaattgc tcacacttat atggcagaag
    12781 aggctttgaa aaaacaagct gcagaaatgg gagtagctat taaagttgaa acaaacggtg
    12841 cttctggtgt ggctaatcgt ttaaccgctg aagatattca gagagctaaa ggagttattg
    12901 ttgcagctga taaagcggtt gaaatggacc gttttgatgg taaacaattc attgctcgcc
    12961 ctgttgcaga tggtatcaag aaaagtcagg aattgatttc tttgatttta aacaatgaag
    13021 gaaacactta tcatgctaaa aatggaaaat ctgaaacagc agtatcaact gagaaaacaa
    13081 gtttaggcgg tgctttctat aaacacttga tgggcggtgt ctcacaaatg ttgccatttg
    13141 ttattggtgg cgggattatg attgctctag catttttatt ggataacatg cttggtgtgc
    13201 caaatgatca gcttggaagt cttggatcct atcatgaaat agcagctatt tttatgaaca
    13261 ttggtggagc agccttttcc ttcatgttac cagtactagc aggttatatc gcttattcta
    13321 ttgctgaaaa accgggctta gtagctggtt ttgtggcagg tgccattgcc tcaaatggtc
    13381 ttgcttttgg taaggtacca tttgcagcag gaggagaagt gagcttgggc ttaacgggcg
    13441 tgccatcagg tttccttggg gcgcttgtgg gtggtttcct tgccggtggt gttattcttg
    13501 cccttcgtaa attgttggca ggcctaccac gttctctaga aggggttaaa tctatcctcc
    13561 tttacccatt acttggcgtc cttgtcactg gtttcttgat gctttttgtc aatattccaa
    13621 tggcagctat taacacagcc cttaatgatt tcttacaagg tctttcagga agctctgctg
    13681 tccttatggg acttcttgtt ggtggaatga tggctgttga catgggtggt cctgttaata
    13741 aggcagctta tgtttttggt acaggaactt tagcagctac tgtggcaaat ggtggttcgg
    13801 tcgttatggc cgctgttatg gcaggtggta tggtacctcc tcttgctgtt tttgtagcca
    13861 ctctcttgtt taaagataaa tttaccaaag aagaacgtga atcaggcttg acaaatattg
    13921 ttatgggact ttcattcatc accgaaggag caattccgtt tggtgcagct gacccagcac
    13981 gtgcgattcc tagctttatc gcaggttctg ccttgacagg agctcttgtt ggtttggctg
    14041 gtattaaatt aatggcgcca catggtggta tcttcgtaat cgctttaaca agcaatccaa
    14101 tcttatatct tgtctttgtt gtgattggtg cccttgtatc aggtatctta tttggcgctc
    14161 ttcgcaaaaa agcctaaaag gtaaagaact tttttcttac taaaactaga atctgtcaag
    14221 gttctagttt tttgctatac tagagttaaa ggataagaaa tgaggacctt tgaaggtgaa
    14281 aaaaaggaga agaagggcta aatcatcagt aaatcgactt gtcttagggt tagtattact
    14341 taatctgatt gttagtatgt ggacactaaa attgggaaac cagcgattag ctccgtatgc
    14401 ggatcacgaa actctgacat ttgtcaggaa gattagtcat gctgctcaat cagtcgctca
    14461 aaagaaacag ttatacagtt cggtgatgat ggctcaggcc attttagaat ccaataatgg
    14521 taagtcacaa ctaagtcaaa aaccttatta taattttttc gggattaagg ggagctataa
    14581 agaacggtca gtcatttttc caactttaga agacgatgga caagggaatc tttatcaaat
    14641 tgatgctgct tttcgttcct atgggagcct gacagcttgt tttttagatt acgcaagagt
    14701 tttgaatgat ccactttatg acaaaaccca caaaaagttt tggtctcatt atcaagatgc
    14761 tactgcaacc ttaacaggca cttacgccac tgatacaact taccatacca aattaaatga
    14821 attgattgaa tggtatcaac tcactaattt tgatggtcta atgaaatagt tatccacaat
    14881 tttaaaaaaa atcagaagaa atatgtcgat ttcaagacaa aagttatcaa tctcattaaa
    14941 ttatctgtgg aaaagttaat ttaaacgttc gtgtgctata atagaaacat agaaaatgaa
    15001 taaaaaagga tatatgaata atgacaaaaa agaaaggtaa gcttgtactt atcagtcttt
    15061 ttgttctagc agcttgttta ggagcttata gtgcaatgag acaatctcat aaaacttcaa
    15121 acgtgtcagc tgagactatc gccagttctt caacccgaca ttttattgat gaaattggtc
    15181 caactgctag tactattggt caagaacgtg atctttatgc gtctgttatg atagcacaag
    15241 cgattttaga atcaagtaat ggtaaatcaa gtctaagtca agcaccttat tataattttt
    15301 tcggtattaa gggtgcctat aacggttctt ctgtgacgat gtcaacttgg gaagatgatg
    15361 gtaatggcaa tacctatacg attgatcaag cctttagagc ttatccaagt attgcagact
    15421 cccttaatga ctacgcggac ttgctaagtt ctagcactta tataggtgct agaaaatcaa
    15481 acacgctatc gtatcaagat gctacagcag ctctaactgg cttatacgct acagacacca
    15541 gttataactt aaaactaaat aatattattg caacctatgg tttgacggct tatgatgttg
    15601 ctaatagctc agctcaagaa actggtctag caacttcggg ttatgtttgg aatgaatatc
    15661 gtcgtaatta cactgatgcg gagaccctag cagttgatga ggcttgggct aaacgcatga
    15721 cttattaatg taacactaac aacaatctgc ttgcactgac cccaaaaaag ctggatactc
    15781 tattttaagt aaaggattta gttctgtatt gtacagaact aaatcctttt agttttactt
    15841 tgatatgttt atcgttgtaa taatcaatgt catttgtaat cgcttgttct aagtcttcta
    15901 gtgatttata gttattctca taaccataga acatttctga ctttaagatg ccaaagaaag
    15961 attccatcat gccattgtca ggactgtttc ttttacgtga catagacgga cgaattcctt
    16021 tagagtttag gaaatgatga taatagttgt gttgatattg ccaaccttga tcactctatc
    16081 atatagttcc gtcatagcat ttatttggag atgccttttt ccattattgg tttaatgtga
    16141 tttaagcaag gttattagct aaatttaatg ccagacaaaa ataccccaat tattagattt
    16201 tttgtctaac ttttggggcg caattcaatc tgagcagttt tagatttggt atcaatgtta
    16261 ttataggtca attgatcata tttatccaaa gcttttagct tatttagtcc aaag
//
LOCUS       DAUGJR010000040        15672 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUGJR010000040 DAUGJR010000000
VERSION     DAUGJR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15672
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.040"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            65..718
                     /gene="grab"
                     /locus_tag="VH800_001422"
     CDS             65..718
                     /gene="grab"
                     /locus_tag="VH800_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G-related alpha2-macroglobulin-binding protein
                     GRAB"
                     /protein_id="HEQ8362485.1"
                     /translation="MGKEIKVKCFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALADQT
                     DALQSEEAAVVKADNAASDALEALADQTDALQSEEAEVVQSDNAASDAWEKAATPIAL
                     DVKKTKDTKPVVKKEERQNVNTLPTTGEESNPFFTAAALAIMVSTGVLVVSSKCKEN"
     gene            956..1498
                     /locus_tag="VH800_001423"
     CDS             956..1498
                     /locus_tag="VH800_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8362486.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1507..2790
                     /locus_tag="VH800_001424"
     CDS             1507..2790
                     /locus_tag="VH800_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8362487.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2806..3666
                     /locus_tag="VH800_001425"
     CDS             2806..3666
                     /locus_tag="VH800_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEQ8362488.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3668..4633
                     /locus_tag="VH800_001426"
     CDS             3668..4633
                     /locus_tag="VH800_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEQ8362489.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSIF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4744..6027
                     /gene="aroA"
                     /locus_tag="VH800_001427"
     CDS             4744..6027
                     /gene="aroA"
                     /locus_tag="VH800_001427"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEQ8362490.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLNAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSNMKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6020..6511
                     /locus_tag="VH800_001428"
     CDS             6020..6511
                     /locus_tag="VH800_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ8362491.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSIIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6719..8170
                     /locus_tag="VH800_001429"
     CDS             6719..8170
                     /locus_tag="VH800_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8362492.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILILGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSVAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8219..9607
                     /gene="rlmD"
                     /locus_tag="VH800_001430"
     CDS             8219..9607
                     /gene="rlmD"
                     /locus_tag="VH800_001430"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8362493.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSSARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQT
                     HHVECVVLLIKE"
     gene            9646..10424
                     /locus_tag="VH800_001431"
                     /pseudo
     CDS             9646..10424
                     /locus_tag="VH800_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            10509..10910
                     /locus_tag="VH800_001432"
     CDS             10509..10910
                     /locus_tag="VH800_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEQ8362494.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(11017..12501)
                     /locus_tag="VH800_001433"
     CDS             complement(11017..12501)
                     /locus_tag="VH800_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEQ8362495.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNNYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            12875..14095
                     /locus_tag="VH800_001434"
     CDS             12875..14095
                     /locus_tag="VH800_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8362496.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLYFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            complement(14215..14580)
                     /locus_tag="VH800_001435"
     CDS             complement(14215..14580)
                     /locus_tag="VH800_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEQ8362497.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            14695..15426
                     /locus_tag="VH800_001436"
     CDS             14695..15426
                     /locus_tag="VH800_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8362498.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKEVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
     gene            complement(15475..>15672)
                     /locus_tag="VH800_001437"
     CDS             complement(15475..>15672)
                     /locus_tag="VH800_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEQ8362499.1"
                     /translation="PDNGMMDSFFGILKSEMFYGLETTYQSLDKLEEAITDYIFYYNN
                     KRIKAKLKGLSPVQYRTKSFQ"
BASE COUNT         4867 a         2717 c         3327 g         4761 t
ORIGIN      
        1 tataatttcc aaattatcgg taatttaata tgctaatgca tataaaaata aaaaaggaga
       61 aacaatggga aaagaaataa aagtgaaatg ctttttgcgt agatcagctt ttggattagt
      121 tgcggtgtca gcatcagtat tagtcggttc aacagtatct gctgttgact cacctatcga
      181 acagcctcga attattccaa atggcggaac cttaactaat cttcttggca atgctccaga
      241 aaaactggca ttacgtaatg aagaaagagc cattgatgaa ttaaaaaaac aagctattga
      301 ggataaagaa gctacgacag ctatagaagc agcaagttca gatgccttag aagcattagc
      361 ggatcaaaca gacgctttac aatcagaaga agctgcggtt gttaaagcgg ataacgctgc
      421 tagtgacgcc ttagaagcat tggcggatca aacagacgct ttacaatcag aagaagctga
      481 agtagttcaa tcagataacg ctgctagtga cgcctgggaa aaagcagcaa ctccaatcgc
      541 tttagatgtt aagaaaacta aagatacaaa acctgtagtt aaaaaagaag aaagacaaaa
      601 cgttaatacc cttcctacaa ctggtgaaga gtctaaccca ttctttacag ctgctgcgct
      661 tgcaataatg gtaagtacag gtgtgttagt tgtaagttca aagtgcaaag aaaattagtt
      721 gctatttgtt ctagcaaatg aaacaaggga atcgaaagat tctctttttc tgatatttaa
      781 aaatgctaca gtttataata gcttgaaaga ctaaatgttc tcaaactcat tagaacaagc
      841 tttaataaaa ctaacccagt tgtatcaaag gatagataaa gactaagact gttatagaat
      901 atttgcaaaa gatttgttat aatggaccca atacaggtat tgtgaaaggt ataatatgga
      961 tatttggaca aagcttgcag tgtttgcttt ttttgagact ccgaaagtaa tattacggcc
     1021 ttttcgctat gaagatcatt gggattttta cagcatggtt aacgacacta aaaaccttta
     1081 ttatgttttt ccagaacaaa aaactaaggc agcaagtgac tatcttttag tacatagttt
     1141 tataaagttt cctttaggtc agtgggcaat agaagataaa gcaacccacc aagtaatagg
     1201 ttctattaga attgagcatt atgatgctaa aacgcgttgt gctgatattg gctatttttt
     1261 aaactatgcc ttttggggac aaggaattat gacagaagtc gtaataaaac ttgtttattt
     1321 atcttttcac gaatttggtc tcaaaacgtt gcgtattata actcatttag aaaataaggc
     1381 cagccagaaa gtagctaaaa aagcaggttt tcaactaaaa acctgtttta aaggaagtga
     1441 tcgtaatact cataaaatct gcatttataa aatgtaccaa ctaactaatg ataggtgata
     1501 atcattatga gcaaacatca agatatttta gattatttag aaaaacttgc tattggtaaa
     1561 aaagtgagtg ttagaagcat ttcaaaccac ttaaaagtaa gcgatggaac agcctaccgt
     1621 gctattaaag aggcagaaaa tcgaggtatt gtcgaaacca aaccaagaag tggaactgtt
     1681 cgtattgaaa aaaaaggacg ggttcgtatt gaccgtctga cctattccga aattgctcgg
     1741 atcagtgatt cggaagtgct agcgggacat gctggtttag gacatgaatt tagtaggttt
     1801 tcaattggtg ctatgactca acaaaatatt cgtcgttact tggtcaaagg agggttatta
     1861 atagttgggg atcgtgaaac gattcaactc ttagctcttg aaaaccataa tgccattttg
     1921 gtgacgggcg gatttccagt atccaaacgt gttattgaaa tggcaaataa ccaacgaatc
     1981 ccagttatgg taactcatta tgataccttt actgtggcaa caatgattaa tcacgcgcta
     2041 tctaatattc gtattaaaac agatctcaaa acagttgaac aggtaatgat acctattaca
     2101 gattatggtt acctttgcga agacagctct gttgaagaat tcaatacatt aataaaaaaa
     2161 acacgacaag tcaggtttcc tgtattagat tataaaagaa aagtgattgg tgtagttagt
     2221 atgcgtgatg tggtggatca gttgccaaca actaagctta ccaaggtcat gtctaaaaat
     2281 ccaataacgg ctagaccaaa tactagtctt gctaatatta gccagaaaat gatctttgaa
     2341 gatttaaaca tgttacctgt cactgacgaa gaaaacaatt tacttggtat gattactcgt
     2401 agacaagcaa tggaaaattt gccaaatcac caaccaaata acccctatac ttatagtgag
     2461 caaatacttt ctaaccttga agaaacggtt gattattatc aagtagtagt tgagccaaca
     2521 atgattgata gtgctggtaa catgtcaaac ggtgttattt cagagttctt aaaggaaatt
     2581 agtatcagag ccctcacgaa aaagcaccaa aaaaatatca ttatcgaaca aatgatggta
     2641 tactttttac atgctattca aattgaggat gaattaaaaa tatatcctaa aatcattact
     2701 gaaaatagac gaagcagcac cattgatatt gaaatttttg tggatgatca agtgattgct
     2761 aaagctatta ttacaacgaa aataaattag aggagtaaca aaacaatgat aacattaaaa
     2821 tcagcccgtg aaatagaagc gatggataga gcaggagact tcttagcagg tatccatatt
     2881 ggcttaaggg atattattaa gcctggtgtg gatatgtggg aagtggaagc atatgttcgt
     2941 cgccgttgta aagaagacaa cgttcttcct ttgcaaatag gggttgatgg tcacatgatg
     3001 gactatcctt atgcgacctg ttgtggtcta aatgacgaag tagcacatgc ctttccccgt
     3061 cattacattc tgaaagaagg ggatttgctt aaagttgaca tggtactcag tgagcctttg
     3121 gataaatcaa ttgttgatgt agcagcttta gattttgata acgtacctga gatgaagaaa
     3181 tggacaggat cttataccgg tggtttagct gactcttgtt gggcttatgc tgttggaaca
     3241 ccgtctgacg aaataaagca attaatggat gtcaccaaag aagccatgta ccgtggtatt
     3301 gaaaaagcag taattggcaa tcgtattggt gatattggcg cagctgttca agaatacgct
     3361 gaaagcttcg gttatggtgt cgtgcgtgat cttgttggtc acggtgttgg tcctacaatg
     3421 catgaagagc caatggtacc aaactatgga acagcaggtc gtggacttcg tctaaaagaa
     3481 ggcatggtct tgactgttga gccaatgatt aatacaggaa cttgggaaat tgataccgac
     3541 atcaagacag gttgggctca taaaacccta gatggtggtt tatcttgcca atacgaacac
     3601 caatttgtga ttactaaaga tggtcccgtt attttaacaa gtcaaggaga agaaagaact
     3661 tactaaaatg gcagaaaaaa aatggtttga taaggtactg tccaagtggc agtatgaacc
     3721 cattcaagtc tttatgaggc atttacaaag tgcagaaatg gatttatctg ccattgcggt
     3781 tgcgtattac cttatcttaa cggcctttcc attaattgtt attgcagcca atatttttcc
     3841 ttacctcaat attgatattg ctgatttgtt acgtttaatg aagcaaaatt tgcctaaaga
     3901 tatttttaga ccggcttctg caattgtaga aaatattttc tctaaaccgt ctggaagtgt
     3961 tttgggagta gcgactttga caggattatg gacaatgtct cgaagtttga catcgctaca
     4021 aaaagctatt aataaagcct atggcgcttc tcagcatcga gatttcttta tcggacactt
     4081 ggttggtttg ttgaccagtt taattatttt atttttatta gcctttgcct taatcttttc
     4141 aatattttct aaagctgcta ttcaagtgct ggataagcat taccatttga gtgataatat
     4201 cacaacgatt ttcttgctcc tcattcaacc tattacagtt ttgattattt ttgttggctt
     4261 gatgctacta tattttttat tacccaatgt taagattaaa aaaattcgct acattttacc
     4321 aggaacccta tttacatctt ttgtgatgac atttttgagt aatctggttg gcaattacgt
     4381 tgtgtataat gttgagcgga tggtagatat taaaatgttt ggttcagtta tgatttttat
     4441 catcatgcta tggtttattt tcttagcaag aatcctgatt ttaggagcta tatttaatgc
     4501 gacctatcaa gaaatgtcct tggggaaatt agaaggtcgt agtggtgata tgatcgctat
     4561 ccttaaaaaa acacttggga atgattcaga tctatctcct tcacagtcta tcgaagatag
     4621 tcacactgat tgatacaaaa aagataataa gtcgtggagt gagaaactat tttcttgctt
     4681 cattttttat gaggatgaat agaaaatcat tgatcttagc aaatagaaag gcagatgaaa
     4741 cggatgaaat tgcgaacaaa tgcaggacca ttacagggaa cgattcaagt tccaggagac
     4801 aagtccatta gtcaccgggc agtcatatta ggagccgttg ctaaagggga aacacgagta
     4861 aaaggactct taaaaggaga agatgtgctt tccacgattc aagcctttag gaatttgggg
     4921 gtccgtatcg aagaaaaaga tgaccagctt gtgatagaag gtcaaggttt tcaaggattg
     4981 aacgctcctt gtcagacact taatatggga aattctggaa cctctatgcg cctcattgct
     5041 ggcttattgg caggtcaacc ttttagtgtc aaaatgattg gcgatgaaag cttatccaaa
     5101 cgtcctatgg atcggattgt ttatccgtta aagcaaatgg gggttgagat atctggagaa
     5161 acagataggc aatttcctcc actacaattg caaggtaatc gtaatttaca accaatcaca
     5221 tataccttgc ctatctcttc tgctcaggtt aagtcagcta ttttattagc agctttgcaa
     5281 gcaaaaggaa caacacaggt tgttgaaaaa gagattactc gaaaccatac agaagaaatg
     5341 attcaacaat ttggtggacg attgatagtt gatggtaaac gcattacttt ggtgggaccc
     5401 cagcagctca ctgctcaaga gataactgtc cccggagata tttctagtgc agctttttgg
     5461 cttgtcgccg gcttaattat tcctggttcg gagctccttt taaagaatgt tggagtcaat
     5521 ccgacacgaa cagggattct tgaagtggtt gaaaaaatgg gagcacagat tgtctatgaa
     5581 gatatgaata agaaagagca agtaactagt attcgagtgg tatattctaa catgaaagga
     5641 actatcatat caggaggtct tatccctcga ttgattgatg aactgcccat cattgcactt
     5701 cttgcaaccc aagcacaagg aacaacctgt attaaagatg ctcaagaatt acgagtcaaa
     5761 gaaacagatc gtattcaagt agtaactgat attcttaaca gtatgggagc taatatcaaa
     5821 gcgacagcag atggcatgat tatcaaaggc cctacggtac tatatggggc taacacaagt
     5881 acctatggag atcatcgtat tggtatgatg acagcaattg cagccttgct tgttaaacaa
     5941 ggacaggtcc atttggataa agaagaagcc atcatgacgt cttatccaac gtttttcaaa
     6001 gatttagaaa ggctgtgtca tgactaaagt gttattggga tttatgggag tggggaaaac
     6061 aacggtttcg aaacacctaa gtatgcactg taaagatatg gatgctatta ttgaagctaa
     6121 aatcggtatg tctattgcag ctttttttga acagcatgga gaaatagcat ttcgaacaat
     6181 tgaaagtcaa gtgttaaaag atctattgtt tgcaaatgat aatagtatca tcgtaacagg
     6241 tggcggtgta gtggttttac aagaaaatcg acaattactg agaaaaaatc accagcataa
     6301 tattttattg gtagcttctt ttgaaacttt gtaccagcgt ttaaaacatg ataaaaagtc
     6361 tcaaagacct ctatttctta agtactctaa ggaagcattt tatgaatttt atcaacaacg
     6421 tatggtattt tatgagggac tttcagattt agtaatcaga gttgaccatc gtacgcctga
     6481 agaagttgcc aacatcattg agggttatta gtaggtcatt gtcgtaatct gatatttatg
     6541 gttttaaaca ggtatctgtc taaagcactt cttatggcaa gttggcttta ttaaatatta
     6601 ggaaataatc ttgattattc tataatgatt aaaattttga gaggacaatc tggctaatat
     6661 aggttataat ggtagtattc gttaaaagtg caattgtaat actaagagat gataagatat
     6721 gacaaaatac cccatgggtg gccttagtca ccatgaagaa ttacgttatt tttatctcct
     6781 aaggaatttg agttacctta gtgagaatga aaaaaaagag tttgcttttt taaaatctaa
     6841 attggaaatt ggtcgagctt atgctccttc taagcagcat tataggaagt caaaacggca
     6901 agaaccttac tttgaagatg actactataa cgactactca ccaaatgatt tactagaaga
     6961 tgatgacgtc aatcatgact cttcttttgt tccatatggt ttaccgatat atcctaaaga
     7021 agacagatat ttaaacaaaa aaacaaaact tacagctcgt agacctatag atgctccgca
     7081 gcctattgat gaagacgatg cttttttaac agagtctgtt gctcgttgtg ctcttcctag
     7141 atctcaaaaa aggaagcata agaaaaaagg atgtatgaaa tggtttttta acattcttgg
     7201 cttattgcta atgactgtgc ttatggggtt agggttgatg tttgcaaaag gggtttttga
     7261 tatttctact aataaagcta attacaaacc agctgtttcc caagcttttg atggtcaaga
     7321 aactcaagat ggtacgaaca ttctgatttt gggttctgac caacgagtta ctcaaggttc
     7381 tacagatgct cgcacagata ccattatggt tgtcaatgtc ggcaaccatg ctaaaaaaat
     7441 aaaaatggtc tcttttatgc gtgacacttt gattaacatt ccaggataca gttataatga
     7501 taattcgtat gatcttaaat taaatagtgc atttaatctt ggagagcaag aagatcacca
     7561 cggagcagag tacgttcgac gggccttaaa acataatttt gatatcgaca ttaagtatta
     7621 tgtgatggta gattttgaaa catttgcaga agctattgac accttgtttc caaatggtgt
     7681 taagattgat gccaaatttg cgacagtagg tggtgtagct gttgactccg tagaagttcc
     7741 agatgacttg cgaatgaaaa atggggttgt tcccaaccaa accatcgaag ttggagaaca
     7801 acgcatggat ggtagaacct tgctcaacta tgctcgtttc cgtaaagatg acgaaggaga
     7861 tttcggacga accgtccggc agcaacaggt tatgtcagct gttatgtccc aaatcaaaga
     7921 cccaactaaa ctctttacag ggtctgtggc tattggtaaa atctatgcgc tgacttcgac
     7981 caatgtttct ttcccatttg ttgttaaaaa tggtgtttct gttttaggaa gtgggaaaaa
     8041 tggagttgag cacgtgacca tcccagaaaa tggggattgg gttgacgaat acgatatgta
     8101 tggaggacaa gccctttaca tagattttga taagtatcag aaaacgttag ccaaattagg
     8161 tctgcgctaa gatatggtat aatggagagt aactaaagtt gctcttcttt tttgagcaat
     8221 ggttagccct agaaaaggaa aaagaataag aatgttgaaa aaaaatgata ttatccaagt
     8281 tgctatttca gatttaagcc atgagggagc aggtgtcgct aaacacgatg gttttgtttt
     8341 ctttgttgat aatgccttgc cagaagaagt gattgacatg cgtgtcttaa aggtcaataa
     8401 aaacagcggt tttggcaaag tagaagccta tcattacctg tcgtcagcta gaaatgcaga
     8461 tgtcaattta acttatttgc gaacaggcat tgcagacctt ggacatctaa cttatgaaga
     8521 ccaactgact ttcaaaaaga aacaagttca ggacagcctc tataaaattg ctggaatcag
     8581 tgacgtgaca gtcgaaagca cgattgggat gacagaacct ttagcttacc gaaataaggc
     8641 tcaagttcct gttagacgtg ttaatggtca gctagaaaca ggctttttcc gcaagcattc
     8701 tcatgacttg attcctattt cggattatta tattcaggac aaagagattg atcgtctcat
     8761 taattttacc cgtgatttat tacgccgctt tgatattaaa ccgtatgacg aaacagaaca
     8821 aacaggtctc ttgagaaata ttgttgttcg ccgaggtcat tactctggag aaatgatgct
     8881 ggtcttagtg actacacgcc caaaagtttt ccgtgttgac caagtcattg aaaaaatcgt
     8941 tgaagctttt ccagcagtgg tgtctattat tcaaaatatt aatgataaga acaccaatgc
     9001 aatctttggt aaagatttca aaacgcttta cggcaaggat accattactg atagcatgct
     9061 tggaaacaac tatgccattt ctgctcagtc tttctaccaa gtgaatacgg ttatggcaga
     9121 aaaactctat caaacagcta tagccttttc agacctttct aaagatgata ttgtgattga
     9181 cgcctactca ggtatcggaa ccattggcct atcatttgct aaaaccgtta aagctgttta
     9241 tggtgttgaa gtgattgaag cagctgttag agatgctcaa cagaatgccg ctcttaatgg
     9301 catcaccaat gcctactttg tcgcagatac cgcagaacat gccatggcaa catgggcgaa
     9361 agatggcatc aaaccaagtg ttattctggt agacccgcca cgaaaaggct taacagaaag
     9421 tttcatccaa gccagcgtgg caatgggacc acaaaaaatt acctacgttt cctgcaaccc
     9481 agccaccatg gcgcgtgaca taaagcgtta tcaagagttg ggttacaaac tggccaaagt
     9541 acagcccgta gatttgtttc cgcaaacgca tcacgtcgag tgcgtagtgt tgctaatcaa
     9601 ggagtaaggt agctgcctcc acatgacaaa aataaggaga aacgaatgcc tattaccaaa
     9661 cacgagattc cccttttaga atgtgatagt aatccatcag ccgtcattat ctagctattt
     9721 agcttccagc taagtgtgtc tatgctttct tagaagacga gattgaagct tttgctttag
     9781 accatcaagg taaaaaagta gcagaattca tttcagccac aaaggtttac cctgtttatc
     9841 agatatctta taaaggccaa gacatttgcc tagctcaagc tcccgttggc tcagctcctg
     9901 cggcgcaatt catggactgg ctgattggtt atggggttaa agaaatgatc agtacaggaa
     9961 cctgtggcgt tttggttcct atcgcagaaa accgtttttt agtgccagtt aaggctttgc
    10021 gagatgaagg aacaagttat cattacgtgg caccatctcg ttatattgat attgatccta
    10081 agatgcttag actgattgag aaaacgcttt tagcacaggg gttagcttat caagaggtca
    10141 tcacctggtc aacagatggt ttttaccgag aaaccaaaga aaaagtggct tatcgccagg
    10201 aagaagggtg ttcggttgtt gagatggaat gttctgcctt agcagcagta gctcaattaa
    10261 gaggcatcct ttgggggcaa ctcttattta cagcagatac tctagcagat gtagaggttt
    10321 acgatcaacg caactggggc gctgattcct ttagttttgc gctccattta tgcttggaag
    10381 tgctcaatac gctagaaaag gatggaaagg ctactgattt ttgaaacatg agctctgcct
    10441 tctgttccta tttgtagtat aatgaggctt gtattgcttt tagactaagc ttagaaaaga
    10501 gaaaaacaat gtcagattta acacaagaga tgaccttaaa tgttattagt atttttgata
    10561 attaccaaat tgaacttgct gaaaaaggac accttatttt aagtactgaa gtgactgaga
    10621 cggctttgaa ttattatggg aatgcccatg gtggttatct tttcactcta tgtgatcaag
    10681 taggtggttt ggttgctaga actactggcg tagaatctgt caccttacag gccaatgcta
    10741 actatttaaa agcagggcac aagggagaca agctgatggt tgaaggtcga ttggttcatg
    10801 gaggtcgaac cacgcaggtg gttgatgtga cgattcataa ccaaacagga gctcttctaa
    10861 caaaaacaag cttgaccatg tttgtgactg gccgacgtca taacgggtga ttaatgaatc
    10921 atagaaggct aaaaaagtcc caactctctg agaattggga cttttttcct ttattgagag
    10981 ataccataaa tcacccgtta gacgggtggt tatggtttat ttacggtaaa gtttgtgatg
    11041 ttggtaaaca gggtcaaagg taatatttac cccaagtttt cggagtacat ttttatcttc
    11101 ttcggttaag ataacggtag aatgggcttc gctacctttc aaattgccaa gttctttcat
    11161 ggctagatta gcttcttcac tagtcatagc agtaatggcc aacgcaatca gaatttcatt
    11221 ggaatgaagc cgcggattgt gactgcctaa gtggttcact ttgaggcctt gaataggttt
    11281 cacgtattcg ggttcaatca aatgagtggt tttatcaatc tttgccaagg ttttaatcgc
    11341 attgatgata acagctgcag ttggtccaaa gagttcagat gttttacctg tcacaatctg
    11401 cccatttggt agttggagag caagggcagg ttggcctgtt tgctctgctt tttgatgagc
    11461 agctacagta acgtgacgat cgtcaggggt gacaccgata tcattcatca agagctcaat
    11521 ttttttgaca gcagattctg tgactcgctc tgccttgaaa tccacgaggg tttggtaata
    11581 acgacggatg atttcttgtt tagaagcttc gatagcagct tcttcattga cgatagaaaa
    11641 accaaccatg ttaacaccca tatcggttgg tgaggcataa ggagacttgc tcaaaatacg
    11701 ctcgaaggtc cgatttaaga caggaaagac ctcgatatca cggttgtaat taacggccgt
    11761 tttgccataa gtttccaaat ggaaggggtc aatcatattc acatcatcta ggtctgccgt
    11821 ggctgcctca taagccagat tgacagggtg atgaagagga agattccaaa ctgggaaggt
    11881 ttcaaattta gcatagccag acttaacccc attgatttgg tcgtgataca tttgggacat
    11941 gcaagtggct aattttccag acccagggcc tggtgctgta acaacgataa ggttacgact
    12001 cgttttgatg taattatttt tccccatccc ctcagatgag ataatatgat taatatctgt
    12061 cgggtagccc ttgataggat aatgcaggta agaagcaatg ccattttttt cgagttgctt
    12121 gcgaaaggca tctgcagcgg gttggttatt gtattgagta ataacgacag aacctacgta
    12181 aatatctaac gtgttaaatt tgtcaattaa gcgaaagact tcttggtcat aagaaatgcc
    12241 taaatcacca cgcgctttag aatgttcaat attattagcg ttaatggcaa ttacaatttc
    12301 gacttgttct ttgagctctt tgagtaattt aatcttattg tcaggttcat agccaggaag
    12361 cacacgggca gcatggtaat cttctaacat tttaccacca aattccatgt aaagcttgcc
    12421 atcaaattgg ctgatacgtt ctaaaatatg atctctttgc aagtttaaat acttgttaga
    12481 atcaaaagca atagtcttca ttttttcacc tctgtaaagc attataacaa agaaattcca
    12541 agaaagaaaa ggttttttgc agggatacct cattttgtga ctttttaaaa aaacttaggc
    12601 ttggttctta gaagaaaaat gtatccgcta tgttcaaaag aacttgacaa ttaaaatgag
    12661 ctttactata ctagtaacaa ttaaatacta ctttaaacat gttccgtgaa gcatgaaagt
    12721 cttaacagta aagagagttt ttttgtcatc tcttattatt tagtgaactt tgatggactt
    12781 gcggacttgt ttccaagtct ttttttgacc tttggacaaa gggtattcaa ttaattaagg
    12841 tagtcagtga gctactatta agaaggagac aattatgtca acattatcat tggacaccac
    12901 aaataagcga gctttagtgg cagctattgc agcttcagga acggatgact tgaatgtcat
    12961 gtttcttgcc ttttccatgt cttccattat gacagacttg ggtcttagtg gcactcaggg
    13021 tggctggatt gcgaccatta ccaatttagg aatgttggtg ggaggcctct tattcgggtt
    13081 gctggctgat aggcaccaca agtttaaggt ctttaaatgg acgattttac tgttttcagt
    13141 agcaacagga ttaatttatt ttacccagtc tttgccctac ctgtacctga tgcgatttat
    13201 tgctggcata ggagttggag gtgagtacgg tgtagccatt gccataatgg cagggattgt
    13261 accaccagaa aaaatgggtc ggatgtcttc tttaaatggt attgctggcc agcttggctc
    13321 tattagttcg gctcttttag cagggtggct ggctccaagt ctaggctggc gtggcctttt
    13381 tctctttgga ttacttccga ttctcttggt gatttggatg actttagcca tagatgacca
    13441 aaaaatttgg gatcattatg ggcaagagga ggaagaatgc agtcaaccaa ttaaaatcaa
    13501 tgaactattc aaaacaaaat ccttaacagc tcaaaccctt gctttaatgg tcatgacgac
    13561 tgtgcagatt gcgggctatt ttggaatgat gaattggttg ccaaccatta ttcaaacaag
    13621 cttaaacctt tcagtaaaaa gttcgtcttt gtggatggtg gctactattg tcggcatgtg
    13681 tttggggatg ctgtattttg gtcagctttt agattgcttt ggtccacgtc tgatttattc
    13741 cctcttttta ttagcatcat ctatttgtgt ttaccttttt caatttgcca attccatggc
    13801 gagtatggtt attggaggtg ctattgtcgg tttttttgtc aatgggatgt ttgctggcta
    13861 cggggctatg attaccagac tttatcccca tcacattcga tccacggcta ataatgttat
    13921 tttgaatgtt ggccgtgctc taggaggatt ttcgtccgtt gctattggta gtattttaga
    13981 tgcctcaggt atttcaatgg tcatgatttt cctagcttct ctgtatgtga ttagttttgg
    14041 agccatgtgg tctattggtc agttaaaagc agaacgctac caacaattgc gttagcaaag
    14101 agatgggtgt tagtatttga gttactttca ctcacaaagc tattttattg attgagataa
    14161 ccaaaaaggt aagcacttag ggattgctta cctttttggt tcttttcttt tgttttactc
    14221 cgctactttg gccataaaat gtttactgtt caccctaact ctagtatgac aggcttttcc
    14281 aatgagttgt tctcccacaa aagcttccaa gcggaaatcg tattttcggc cttcttcttt
    14341 aagggctgta atgataattg taacaggatc tccaatggct gaagctgcca aatgttggat
    14401 agctatctcg ctgccaaccg ttgtaaagtc actgtcgagc tgttcttggg caaataagta
    14461 agaagcattt tccataaaag caacaagagc aggagtagct aggacattca gcgttcctga
    14521 gcccatggct ttagccgaat gattgggacg ggtttcataa gtgtgagaat aaatagtcat
    14581 aagttaatct cctcgtttct ataagcctat tataatatat taagcgctta cagtcatgaa
    14641 actactgttt ttttatgtta tacttaataa tgaattttct ttgaaagggt tatgatgcgc
    14701 ttagataaat ttttagtggc aactggtgtt ggaactagga gccaagtcaa acttctctta
    14761 aaaaagaagg ctattttcgt caatcaaaag gttgaaacct ctgccaaagc acacattgat
    14821 gaatacaagg atttggtgac gtatcaaggc acgcccttgg tctatgaatc ctttgtttat
    14881 tacctgttaa acaagccgtc agggtatgtg tcagcaaccc aggacagaca gcaggctact
    14941 gttatggagt tgttagatga cacggctagg caaaaagcag tttttcctgt gggtaggtta
    15001 gataaggata cccgtggact tttgctcttg accaataatg gacaactagc ccatgacctt
    15061 ttatccccta aaaaacatgt tacgaaagag tacttggcta aagtagcagg catcatgact
    15121 gaagctgata aagattattt tgctagaggt atttccttaa aggatcacca gtgcctacct
    15181 gctcatttag aagtgcttgc tagtgattta cagcagcaaa caagtttggt taaaattacc
    15241 atacaagaag gaaaattcca tcaggtgaaa cgcatggtag cagcctgtgg aaaggaagtg
    15301 cttgacttac agcgtctcag catgggacca ttaaaactag accctagcct tgcagaaggg
    15361 gagtttaggc gcctgacgcc tgaggaattg cagagcctag caccttattg tcagagctca
    15421 ctataaaaag aaacctcccc ggtcagtact gaccccaaaa agttggacaa ataattattg
    15481 aaaggattta gttctgtatt ggacaggact aagtcctttt agttttgctt taattcgttt
    15541 gttgttgtag taaaaaatgt aatctgtaat agcttcttca agcttgtcaa gtgattgata
    15601 agttgtctcg agtccataaa acatttcaga tttgagaatg ccaaagaagg aatccatcat
    15661 gccgttatcc gg
//
LOCUS       DAUGJR010000041        15527 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUGJR010000041 DAUGJR010000000
VERSION     DAUGJR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15527
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.041"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(20..2011)
                     /gene="uvrB"
                     /locus_tag="VH800_001438"
     CDS             complement(20..2011)
                     /gene="uvrB"
                     /locus_tag="VH800_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEQ8362500.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            2204..4378
                     /locus_tag="VH800_001439"
     CDS             2204..4378
                     /locus_tag="VH800_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8362501.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPTKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            4378..5118
                     /locus_tag="VH800_001440"
     CDS             4378..5118
                     /locus_tag="VH800_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362502.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(5266..5418)
                     /locus_tag="VH800_001441"
     CDS             complement(5266..5418)
                     /locus_tag="VH800_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362503.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(5415..6794)
                     /locus_tag="VH800_001442"
     CDS             complement(5415..6794)
                     /locus_tag="VH800_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8362504.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(6972..7421)
                     /locus_tag="VH800_001443"
     CDS             complement(6972..7421)
                     /locus_tag="VH800_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEQ8362505.1"
                     /translation="MIISAEGDVSIHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYQLEALGENRTRITYSYD
                     YHPLDIFQKANQFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(7418..7753)
                     /locus_tag="VH800_001444"
     CDS             complement(7418..7753)
                     /locus_tag="VH800_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8362506.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(7756..8067)
                     /locus_tag="VH800_001445"
     CDS             complement(7756..8067)
                     /locus_tag="VH800_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8362507.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EMAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(8090..10084)
                     /locus_tag="VH800_001446"
     CDS             complement(8090..10084)
                     /locus_tag="VH800_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8362508.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTIRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVVICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(10190..11284)
                     /locus_tag="VH800_001447"
     CDS             complement(10190..11284)
                     /locus_tag="VH800_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEQ8362509.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIAPS"
     gene            complement(11293..12693)
                     /locus_tag="VH800_001448"
     CDS             complement(11293..12693)
                     /locus_tag="VH800_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8362510.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSNAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDLLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            12918..13613
                     /locus_tag="VH800_001449"
     CDS             12918..13613
                     /locus_tag="VH800_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEQ8362511.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILITLIFYSILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYNWL
                     MLQRYQEKKVKKG"
     gene            complement(13618..13776)
                     /locus_tag="VH800_001450"
     CDS             complement(13618..13776)
                     /locus_tag="VH800_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362512.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(13845..15158)
                     /gene="obgE"
                     /locus_tag="VH800_001451"
     CDS             complement(13845..15158)
                     /gene="obgE"
                     /locus_tag="VH800_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEQ8362513.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDIPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD"
     gene            complement(15215..15343)
                     /locus_tag="VH800_001452"
     CDS             complement(15215..15343)
                     /locus_tag="VH800_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEQ8362514.1"
                     /translation="MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM"
BASE COUNT         4665 a         3316 c         2790 g         4756 t
ORIGIN      
        1 tataagcttt attcaaaacc tagtccatta atttaagttc taaaatcaag tctcgcattt
       61 gagctgccaa ttcgaaatca agtaattcag ctgcctcttg catttgtttt tgcagagcat
      121 tgatcgcttc ttttcgttct cctcttgaca tactttcata atccatctct tcttttgata
      181 tatcattgtg gcttgtttta cttatactaa taaggcctct gatgtctttt tttatagttt
      241 gtggaacgat gccgtgcgct ttgttatatg ctatttgaat ctcacgacga cgagccgttt
      301 cgtcaatagc tcgctgcata gaatctgtca tcttgtccgc atacataatg acatgaccat
      361 ctacgtttcg agctgctcta ccgatggtct gaatcaagcc gcgttcatta cggaggaaac
      421 cctctttatc agcatccaaa atggctacaa gactaacttc tggcacatca atcccttcac
      481 ggagcagatt gattccaatc aagacatcaa aaacaccaag tcgtaaatca cgaataattt
      541 ctgttcgctc taaggtttta atatcactgt gcatatactt gaccttgaca cccatctctt
      601 ttagataatc agtcaaatct tctgccattt ttttagttaa ggttgtgatg aacgtccgtt
      661 catcgcgcgc tacgcgctgg ttaatttctc ccaacaaatc atccatttgc cccatacttg
      721 accttacatc aatttcagga tcaagtagcc cagtcggacg aataatttgc tcaataattg
      781 tattagtctg tgacatttcg tattcaccag gcgttgctga aacatagaca atttggtgca
      841 catgactttc aaattcctcg cgtcttaagg gacgattatc aagagctgat ggcaatcgaa
      901 aaccatagtc aactagcatt tgttttctgg cttggtcacc attatacatg cctttgattt
      961 gtcccattgt catgtgactt tcatcaatca taattaaaaa atcttctggg aagaaatcta
     1021 acaaggtata aggaggttct cctggtgacc tgccatccat atgacgggaa tagttttcga
     1081 ctccgctagt atagcccatt tcacgtaaca tttcaatatc atattccgtt ctttggcgta
     1141 atcgctgtgc ttctagtagt ttaccttcag attcaaataa ctgtaactgc tctgctaact
     1201 ctgcttgaat tttggctatt gattgctcca tatgctcatc atttgttaca aagtgagtag
     1261 ctggaaataa aaccaaatgg tcaacttctc caatagtttt accagttaaa ctttcgattt
     1321 cacatatacg gtcaatctca tccccgaaaa attccacccg aaaagcatgt tcatccctgg
     1381 atgctggaaa gacctcaaca acatcgccac gtacacgaaa acagccgcgt tgaaaatcaa
     1441 tatcattacg ctcaaattga atatctacta attgatttag caaagtgtca cgtgatatct
     1501 cctgacctgg acgtaggctg actgctgaat ctgcgtactc ttttggcgaa cctagtccat
     1561 aaatacaaga tacagaagct accactatga catcgttacg ctcaagtaaa gaagaggtgg
     1621 ctgaatggcg aagtttatcg atttcatcat tgactgaact atctttttcg atataggtgt
     1681 cgcttgatgg gacatatgct tcaggttggt agtaatcata ataggaaaca aaatattcca
     1741 cagcattgtc tggaaaaaat tctttaaatt caccatataa ttgtcctgct aaggttttat
     1801 tgtgagctat cactaaggta ggtttattta ctttactaat tacttggctc atggtgtatg
     1861 tttttcccgt tcctgtagca cctaggagaa tctgagcttt ttctccgccc tcgatattat
     1921 caactaggct ttcaatagct tgtggctgat caccagacgg tttatacttt gattttagtt
     1981 taaatggttt atcatcacgt ttatcaatca ttttataccc tctaatagtc ttactctctt
     2041 atagactatt ttaacataga taagccagaa tcacctccaa taagcgtaaa aaacatgtca
     2101 tttacatgtt atgttttatg acatataaat aacaaatttc ttgcttaatg ttcaatattt
     2161 tgttataatt aaccatattt tttagtttta taaggagatt agtatgacgc acaaaataaa
     2221 agtattgctg cttgcgataa tgtctatttt tttgacatgc aatattgcaa gtgctgaaac
     2281 tattgctatt gtttcagata cagcttatgc cccatttgaa tttaaagact cagatcaaat
     2341 ttacaaagga attgacgttg atattattaa tgaagtagcc aaacgtcaat cttgggattt
     2401 cagtatgagt ttcccgggtt ttgatgcagc tgtaaatgct gttcaatctg gtcaagcgag
     2461 tgctctaatg gccggtacaa ccattacgaa tgctcgtaag aaagtctttc atttctcaga
     2521 gccatattac gataccaaaa ttgtcattgc gacacgtaaa gccaatgcca tcaaaaaata
     2581 cagtgactta aaaggaaaaa cggtcggtgt taaaaatgga acagcggctc aagccttttt
     2641 gaataactat aaaaaaaagt atgattatac tgttaaaaca tttgacacag gtgatcttat
     2701 gtataatagt ttatctgctg gttctattgc cgctgttatg gatgatgagg cggttatcca
     2761 atacgcaatc agccaaaacc aagatattgc tattaacatg aaaggagagc ccattggaag
     2821 ctttgggttt gctgtcaaaa agggaagcgg atatgattat ctagttaatg atttcaatac
     2881 agctcttaaa gctatgaaag ctgatggtac ctaccaagct atcatgacca agtggttagg
     2941 cacagatgat aaagctacca ccagtcaggc aacgggaaat ccatctgcca aagctacacc
     3001 tacaaaggac agttataaaa ttgtctctga ttcgtctttt gcaccttttg aatttcaaaa
     3061 tggtaagggc aaatacgttg gtattgacat agaattaatc aaagctattg ctaaacaaca
     3121 aggtttcaaa attgaaatcg ctaatccagg tttcgatgct gccttaaatg ctgtgcaatc
     3181 tagccaagca gatggggtca ttgctggtgc aactattact gacgctcgta aagctatctt
     3241 tgatttttct gatccttatt atacttctaa tatcatttta gctgttaaag ctggaaaaaa
     3301 catcaagaac tatgaagact tagacagaaa aacagtcggt gctaaaaacg gcacttcatc
     3361 ttactcttgg ttaaaagaaa acgctcctaa atatggttat aatgtcaagg catttgatga
     3421 tggttctagc atgtatgata gcttaaattc aggttctgta gatgctatca tggatgatga
     3481 ggcggttctt aaatacgcta tctctcaagg tcgtcgcttt gaaacacctc ttgagggcat
     3541 ttctactggt gaagttggtt ttgctgtcaa gaaaggaact aatccagaat taatcgaaat
     3601 gttcaacaat ggcttagctg ctctcaaaaa atctggtcag tatgatgaca ttatagataa
     3661 ataccttgac tctaagaaag ctgcaactcc ttctgaaaaa ggtgctgatg agtctactat
     3721 ttcaggccta ttatcaaata actacaaaca actattggca ggacttggaa ccacgctcag
     3781 tttaaccctt atttcatttg ctattgctat aattatcggg atcatctttg ggatgatggc
     3841 cgtgtcacca actaaatcac ttcgacttat ttcaacggtc tttgtggacg ttgttcgagg
     3901 gattcctttg atgattgtgg ctgccttcat tttctgggga gtaccaaacc ttatcgagag
     3961 tatgaccggc caccagtcac cgattaatga tttcttagct gctacaattg cactgtcact
     4021 taatggcgga gcctatattg ctgaaattgt tcgcggtggt atcgaagctg ttccagcagg
     4081 gcaaatggaa gctagtcgaa gtcttggttt gtcttacgga accacgatga gaaaagtaat
     4141 tctcccacaa gctgtgaaac taatgttacc taactttatc aatcagtttg ttatttcatt
     4201 gaaggataca acaatcgtct cagcaattgg tttagtggaa ctcttccaaa caggtaaaat
     4261 cattattgct agaaattacc agtcgttccg tatgtatgct attttagcaa ttatttacct
     4321 tatcatgatt acactcttaa caagacttgc aaaacgttta gaaaagaggc ttaactaatg
     4381 acagaattaa aaattgatgt tcaagattta cacaaatctt atggtcaaaa tgaagtctta
     4441 aaaggaattg atgccaaatt ctacgaaggc gatgtcgttt gtatcattgg tccttctggt
     4501 tctgggaaat caacctttct acgtaccctc aacctcctag agacgattac cagtggtaag
     4561 gtcatggtgg acggttttga attatcagat cctaagacta atattgacaa ggcacgtgaa
     4621 aatatcggga tggtattcca acacttcaac cttttccctc acatgactgt tcttgagaat
     4681 attatctttg ctcctgttga attaggtaaa gagtctaaag aagttgctaa aaagcatggc
     4741 atggcacttc tagaaaaagt cggactttct gataaggccg acgccttccc aggaagttta
     4801 tccggcgggc aaaaacagcg tgtcgccatc gccagaagtt tagcaatgaa cccagatatt
     4861 atgctctttg atgaaccaac ttctgctctt gaccccgaaa tggttgggga cgttttgaac
     4921 gttatgaaag acttggcaga acaaggcatg accatgttaa ttgttactca cgaaatggga
     4981 tttgctcgcc aagtagctaa ccgtgttatc tttacagacg gtggtcaatt cttggaggat
     5041 ggtactcctg aagagatttt tgatcatcct aagcaccctc gtctcattga atttttagac
     5101 aaggtcttaa acgtctaata gagcagacac catactaact tccaaaaaat aataaggcaa
     5161 ggaaacaggt ttccttgcct tttttggtta ctgttattat tcaaaccagc aaaataggga
     5221 tactcttatg actctctcct tcataagagt gtcccctatg cttttttatg ggcgtttatg
     5281 tttagtgagg taataaccta atcccgtaag agctagtccc gtcactatgt gtaagtattt
     5341 gttaccaacc atcggactaa tggcaatgag aaaaaagcca acagccatta aaaaagttgc
     5401 tccatttttt tctgtcatgc aaggtcactc gctttttctt tattggccaa aatgacaaat
     5461 ggtgcccaga taaggaaggc aacaaagagg ttaaacagtg aaaccaaacc tgccataata
     5521 ttacctccag tagctaggta agcataaagt ccaacagggg taatccaagg tactgataag
     5581 aataccggtg gaatcaaacc tattgcagta gcaaaataag ctatgctagc acaaattggt
     5641 ggcacaatta gccatggaat cacaaaggtt ggattcaaaa caattggcat cccaaatgta
     5701 attggttcgt tgatattgaa aacacccatt ggtgcggaca atttggcaat ggttttatgc
     5761 tcttctcgtt ttgagaatat gaagatagca ataatcaatg ccaaggttac tcctgaacca
     5821 cccatttgag cataagcatc aaaggacccg cgtgtccaaa ggtatggtaa attagcagcg
     5881 ctatgcgctg tattgtaagc agctgtattt tctgttaaag ctaccatata aataccatcc
     5941 atcactgggg ctaagacatt atgaccatgc aagccgaaga accagagcag ttgaactaag
     6001 aaggttaaca agataactga accaataccc tgtgataagc ctagcaatgg taattggata
     6061 taggttgaaa tgacatcact tagggaagaa cctgttaatg cgaaaatgag gtaggcgaaa
     6121 attgccgaag cgtaaatcgc aactgttcct ggaataatgg cagcaaaggc tttattaacc
     6181 gcaggtggta cattatctgg taaggtaatg gtaatattac gtttggtcaa agccgcatac
     6241 acaaaacttg ataaaaagcc aataattaaa gctgtgaaca agcctgtggc accgacatac
     6301 tttagagcta ttgctcccca ttgactagtt tcaatacttg aagctccacc cgcagtaacg
     6361 actgaaagcc ccatttcttt caaattgcta attaggttag cagaggcatt ttcaagtggt
     6421 gtcgaaatgg ttaaagtctg aggtagggtg gcaataaatg agccaaaaga aatcaatcct
     6481 cctgccaatg gattaatctt atgcataaca gctaaattgt aaccgaaagc aaaggcaaaa
     6541 aagagcgcca tgataccaat tgtcccaaaa taaacatagc cattgatgtc gataacaggt
     6601 tgcatagctt ttgcaaatcc tgtccatccc atattgtttg gaatatcgcg taaaaaaacg
     6661 ttcaataaga cagcaactga acctgccatg gtaataggca tcattgaaat aaaggaatca
     6721 cgaatagcta ctaaatgccg ttgtgaccca atttttcctg aaatctccat aaacttatca
     6781 gaaaaatgcg acataaatct tctcctcttt ttattttttt aatgtaacaa aggtaacctt
     6841 aaaagcagcg gtgtctgcct aacacaatta tctcaaaatc atccttgtta aacgtgatgc
     6901 ttagagataa ccggtaatcg gctcttatcc aaatgaaccc ttctctctca ttcaaggtct
     6961 gtgaataatc ttcacaaaga cgatggttgc tgcaactgtt tagcatattg gataagggct
     7021 gctaactgag cttgagattg gcgttctagg ctttttttga acagtttgcc aacaataaat
     7081 tgatttgctt tttgaaaaat atctagagga tgatagtcat aagaataggt aattctagtc
     7141 cgattctccc ccagagcctc taattgataa gccaattcct ttatcccatg attggaacta
     7201 aaacaagcag tatataattg cggagcttct agggccgtaa taagcaccct cactgtacgt
     7261 tctttgtatt taccataatg tttaacatag tttatccccg ctttgatatc atctcttgac
     7321 aactgtctca aggtattttg tcgataatct tcttggagcg atatcagcat ggcttcaaaa
     7381 caatgatgaa tggaaacatc tccttctgct gaaataatca tgactcacct ctttgtattg
     7441 ctgacatttt gtcgtaaacg gtaaccaatt ccttggctaa atcaataaag gctaaggcag
     7501 tcatcatgtg atcttgccca tgcaccatca ataaagacaa ttcaaccgca tcaccagctg
     7561 cttcttggga cagcaaatgt gtctgcgatt tatgggcaat atttaacgag tttgtcgctt
     7621 cttgaagtaa gtgctgagcc tcctcaaact gcccatctcg tgctgcatga atagcctcta
     7681 cggccttgcc cttggcttcg cctccataca tgattaagcc cataatagct tctaagttgg
     7741 atggttccgt catgcctact cctccatcat tgctagggct gtttcaagga ctttttcacc
     7801 gttcataaga ccataatcag ccatgttaat ggcatctact ttaatatctg gttcaaactt
     7861 atctttaaaa tcctttagta agaatttgac ttgtggacct aacaagagaa cgtcaatgct
     7921 attagcagcc atttcgttgt cagcttcact cacaggaact gcccaaatag aaacttcaag
     7981 gtcacgcgct tgggctgctt tttgcatctt agtcaccaac atactagttg acataccggc
     8041 attacaaact aacataatag atttcataag gtttctcctt ttaatcgttt taatcatgaa
     8101 taagtggggt aaacactgtc atgaatttgg aataatttgg ttcttctagt aacgcttgct
     8161 gaagctccac ctgattgaca aaagatgcca aacctggtga tacatatttt aacctatgat
     8221 tatgcccttt agacggggat aatagaaaga caaaatgaac agcttgatgc gccttgtccc
     8281 actcaagagg ctctcggcaa ataaccacta ctacctgttc agaataagtc atgggattag
     8341 caggatgcgg aaaggcaagc acttctccat agatgactgg gctgtaattt tccctcagta
     8401 ccatttgatg atagaagtcc tctacaaacg tttctgttcc cgcctcgtca agacaagcaa
     8461 tcatccgtaa aagcaagtct tcctttgaga ttttctcgtc taaataaaga aaacgattag
     8521 ggctaaaaac acctgttaga agctgctctg cttttgctaa actcatctgt gacggtaaac
     8581 tgacctcttt cttgatacct tcttgttctc caataaattg tcgaatagtt tcaatatcct
     8641 gatttgacaa aaaaacactg acagtaatca ctggtgttaa aaacatcaga ttggcaaggc
     8701 tgatagagga aataatcaaa tcaacggttt tcagtcgctc ttcggttatt tcatagtaac
     8761 tgataacatc gacaatacgc aaacgtcctt caaattcctt ttccaagcga tttttcaaca
     8821 tcatggcact accataacct gtggcacaaa ctactagaac cctcaattta tgacggtttg
     8881 aataacgctc aatggccgcc attaaatgca aactaatata agcccattca tcatctgaga
     8941 catcattctt ttgacataca agcaaatccg aaaaggtctg cttggtaagg gtaaatattt
     9001 caggatactg gcttttaatt tcctcagtta aaggattagt cagctgaata tggttttcaa
     9061 gacgtatggt caagggcatc atgtgggcta ataaaccttg aaataaattg gtatctgttt
     9121 ctaaagtcat gcctgtcaat tgactaatct tggcaataca tgcttttaaa tggtcctgca
     9181 acttttcatc ggtattatca tcttgccaat gcttaccaac agaatgtttg acctttagat
     9241 gcagtgcaat ataattagcc tcctctttag gaaaacgtat ccccatcact tcttccactc
     9301 gatacaaaat gcgcagagct acttgatact catcagactg acgaatagct attggaatgg
     9361 aaaacagttc taatggacac cccgatcgaa tacgctgaac cattagggca atatgcaaga
     9421 ctagattatt catgacaaaa tcagaaagtt tcaacttagc atcccgacat tcatccaaga
     9481 caataatcat gatttctgca aaattaatac cttcaagaaa ggtattacct accatggtgg
     9541 acaaggtatt atcaaaacta gtaacaaaaa aatagtccat gataaaatgc ctaatgtcct
     9601 cttctttacc tcttatttga atatgttggt gagttatttc aagctctaac tggtaaggta
     9661 ttatgcgctc cttaatacct gctaaaacat gttttaaagt tgtccgactg atatacaatt
     9721 cttgacaaag ctcttcaaaa tcctgaacgg catcttcaaa aaagaattta tgaagcacat
     9781 aatcttctcg atcaaccgat tcttccactt gagtcacatc tgccaaacgt tttttagacg
     9841 tcacactttc ttgccaaaag atgtcaaatg ccatagaatg gtcaatttct aagcagtaac
     9901 ctcgaccttg tttagaaatg atgtgagctc cgtgttcagg aaggctactg atcagttctt
     9961 tgaggtattt cctaaccgta cggtcactca taccgataac ctcagccaga gttgcactag
    10021 agacaaactg ctctttgtga tggattagaa atgttatgat ggccagttct ttttttgata
    10081 acattagtcc tccttactac tttagaaaac gctttctacc ctcctttagt gtaccaaata
    10141 tttcctgaaa aaggtgacca tcattttccg cattgattgt gaaaagaatc tatgatgggg
    10201 caatctccaa acaaaattcc tgccaaggtc gcaaatcatc taacaaacta agatagtcct
    10261 ctctgacctc agcaaccaca ttagcttttg aactgaccgt aaaatttttc aaagcaattt
    10321 gcagttctcc cttatatcga tgatagcggt cattgtcaat aataatgcta cctcgtttga
    10381 cctccttaga ttggtctctt ggagcaatcg attcctgagc atagactaga cgtggcatgg
    10441 ttgatcgaat cacataatca gatacatcgc cacgataaca atgcggatag ccaatgattt
    10501 gctcctcaac ttctgtcaaa tcgatgatag gcctaacctt gatcgtcgtg actggtcttg
    10561 ctaaagcttg agtacatgct gccaattctt cttccgaaat gaattggtta gatatgagga
    10621 tattatcaat ggttcctatc gctttcatta attctacttg caggccaatg ggcaagtgcc
    10681 tatggtcttc cactgtcggc aagccttctg ccagtagcca agggccttca gatgctgact
    10741 gagcggtaat aaaagcagcc gtttcaatat catgctcatg ataaaaacgt gacatatcct
    10801 taaaatgttg ccatgacaaa ccggtaaatt catgtggata aaaattatgg caaccaataa
    10861 tattgctccg ttctgcatct gtcgctagca atgacatcaa taattgttta tcagtgctca
    10921 tattaagttc aattttaagc ccaaagggat ttcttgttaa agttacaatc tctgctagag
    10981 ggagagcctc gtctaagcgt aagcccgcta acccgaaggc atgagctcgt tcaataagct
    11041 gatctgacca accagcttgg ctaataaagc ttggactaac gtcagcaatc actcgaatgc
    11101 ctaattgatt tgcataagca atgagctctg cgtagcaatg aaacatctgg tgatcagctg
    11161 gtgccagctg taagagactc ataaacaagc gcttggctcc atagctatga cataagtcaa
    11221 tataagcttt actcttggta acatcatacc gctcagggta tagagaaaat cctaaatcaa
    11281 ccatattgcc tcctatttat caaaaccatt tgactcgctc aacgccttaa accagtaacc
    11341 tgattttttt atggttcgct tttgactctc taaatccaaa gctaccaaac catatcggtt
    11401 tttataagca tttaaccaag accagcaatc aataaaagtc cacaagaggt agcctttgca
    11461 gttggctcct tctcccaaag ccttatgaag ctggataaga tgatcctcga taaaggtgat
    11521 gcggtagtca tcttgtatct ggccatctgc taaaaaagct tcttcacctt cgacacccat
    11581 accattttcc gtgactagcc attcgatgtt accatagtgt tcttttaaat taagggcaat
    11641 atcataaagt cctggttcat aaatttccca accccggtga ggattgactt ttttaccagg
    11701 catatcataa ggttcaaaat aaatatctaa gataaggagg tccccctctt gctgtgactt
    11761 actaggtgcc tgaacccgca aaggctgata ataattaact cccaaaaaat caacagtatt
    11821 gtttttgata atctctaatt catcagcact atattgaggt aataaatcag cttcctctaa
    11881 aatggaaact aactctgctg ggtaaacacc caaaactgat ggatctagga aggatttggt
    11941 ttggaaaagc tctgcgattc tagcagcctt gacatcttca ggagcattac tccgaggata
    12001 agcaggtgtc atgttaagca caatactaat cttgtggtcg ggatgaagct tatgacaagc
    12061 tttgaccgcc agtgaactgg ccagttgtgt gttgtaagcc acttgaactg ctgccttggc
    12121 atctacttta caagggtagt gataataacc taaatagcca cattcgactg gaacaatcgg
    12181 ttcattaaag gtaatccaag tgtttactaa atcaccaaaa agctcaaaac aggtttttgc
    12241 gtaggtttca taagcccaga cagtagcttt gttttcccag ccaccttttt cttgcaaggc
    12301 ataggggagg tcaaaatgat agaggttaac aatcaattta ataccttgag caataatgtc
    12361 ttgaaatact tctcggtaaa atgtcaccgc ctttggatta acctccccga ctccttctgg
    12421 aatcaatcga gaccactgga ttgaggtccg aaaaatcgtg tggcctgttt ctttcaaaag
    12481 ggcaatgtca cccttatagt tttcataaaa ggttgaggtt ttttctggac caatttggtg
    12541 atgaaactta gctgactcaa tactaaacca gtaatcccag ttgctaggtc ctttgccatc
    12601 tccaggaacc gttccttcgc tttgaggccc agatgtggaa cttccccata aaaagccatc
    12661 tggaaattga taacggtgtt ttctttgttt catatccttt gtcctttctt tgctcacttc
    12721 tctttttatt ataagaagaa aaacaggtga tgtaaacgct ttaaaaaatc tgttttttcc
    12781 ttatcatcac ggaaaataag tgatttaaag cttgacatat tttattatct taaagagcct
    12841 atctaacctg ccctgctact tcttatcaaa accaagcccc tattgacaga tgccttagcc
    12901 tatgtttgaa taggggtatg gcttatttaa actactttac aaaaaccgag tgggcacttt
    12961 ggttaagctc tgtcttggcc attttaatta gcgccctttt attcggtaag caagctccct
    13021 tagctttaat agcttctttg attggtgtga cctctctcat ttttagtgct aaagctaatc
    13081 ctattggtca agggctcgtc attatttttt ccattatcta tgcctatctt tcattacgaa
    13141 acagttacta tggagagtta atgacctatc tttttatgac cctccctatg actatttttt
    13201 cactttttac ttggttaaac catccttttg aagggaaaaa atcacaagtg actatttcac
    13261 gattaacacc cactgatcga agatgtcttt tcgtttttac tatactgatc actcttattt
    13321 tctacagcat cttggcttct attcaaacag cctatttact tgtctccact ttatcgattg
    13381 ccacttcttt ctcagcggtt tatctcagct ataagcgcag cccttatttt gctttagcat
    13441 acgggctcaa tgatctagtc ctcattctct tatggatgca tgctgctcaa acagatgcca
    13501 gccaatatgc tgtggtcatc tgctttgcca cctttcttat taatgatagt tacacttttt
    13561 ataattggct aatgctccaa cgttaccaag aaaaaaaggt caaaaaagga tgagggccta
    13621 agcctcatcc tttttcaatt tttcacgttc taagcgcaaa cgtctattgg gatttaaaag
    13681 attaaacaat tcttctaatt tctcagcatt ccaaacatct gctgccgata caaaatttcc
    13741 atccttatcc ttaaaggata tcggtttatc acccataatc agaaacctcc atcttaaaga
    13801 taacacacaa gagcactatc acactgctat tgtaatagat tgccttaatc cacaaattca
    13861 aattcaaact tgccaatacg aacaggatcc ccatcttttg ctccacgttc acgaagagct
    13921 tcgtcaaccc ccataccgcg caattgacgg gcaaatttca tgatggactc atcacgttcc
    13981 atattggtca tgacaaagag acgttctaac ttctcaccag acaagaccca agtagcgtca
    14041 tcgtcacgtg tgatctcaaa gtctttttca gtctcagcaa agccatagta agcttcctcg
    14101 tccaccagat cagattcatc atataataag aattcgtctg ttttagcgag taattctgcc
    14161 gttgcttcta acaagttctc taagccttga tgtgctaggc ttgaaatagg gaaaatcatt
    14221 ggcaaatcat caaactcgtc atattgggca gccaattttt tcttgaaggc tttcaagttt
    14281 tcttgagcct ctggtatgtc cattttatta gccacaataa tctgtgggcg ctccatcaat
    14341 cgcaaattat aggtttccag ctcgttatta atggaaacat aatcttcgta aggatcacga
    14401 ccctcactag cagacatgtc aatcacatga agaataaccc gtgtccgctc gatatgacgg
    14461 aggaattgag ttcctaaacc aaccccttgg ctagcacctt caatcaaacc tggcagatct
    14521 gccatagcaa agctatcacc tgactttgta cgaaccattc caagattagg aacaatagtg
    14581 gtaaaatgat aggcaccaat tttcggttta gctgatgaca caacacttaa caaggttgat
    14641 ttcccaacag atgggaatcc gaccaagcca acgtcagcta agattttgag ttctaactct
    14701 aactgacgtt cctcacctgg ctcaccattt tcagcaatct ctggcgcagg attacgagga
    14761 gttgcaaaac gaatattccc acggccacca cgaccaccct tagcaatgac cacttcttga
    14821 ccatgttcta ctaagtctgt aattactttt ccagtttcag catcacgaac cgttgtccct
    14881 tgaggaacaa agacaatcaa atcttctgca ccacggccgt gcatgccttt ggtcatacct
    14941 ttttcaccag atttcgcctt gaatttacga ttataccgga aatccatcaa ggtacgcaaa
    15001 ccttcgtcca ctcggaagat aactgagcca cctttaccgc cgtctcctcc ccaaggaccg
    15061 ccatttggga cgtacttttc acgacgaaaa gctaccatac catcgccacc acggcctgct
    15121 tggacactga tttttgccgt atctaaaaac atactcatac tttttttatt ctctaacttt
    15181 cttttacttt aaaaaaacgc ctttcagcgt ttccttacat taatactgat agggcactcg
    15241 caataagccc gccaacagtt acaagaacca ttaggataac aacaaacatt gtcacttttt
    15301 caaaggttgt ttttttgcga ggtccatttt ctccaaatgc cacattaaat acctcatcta
    15361 ttgatttttc ttcttatatc ttaacatgaa agatcgtttt aggcaaatat cagatgaata
    15421 tttacgctat gtaggctatt actgagtatt gtatcttgtg aatttcatat gaatatgata
    15481 cattagcatt tgcaaaataa tgttacagat aaaaacctcc tcgtctg
//
LOCUS       DAUGJR010000042        14574 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUGJR010000042 DAUGJR010000000
VERSION     DAUGJR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14574
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.042"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            11..715
                     /locus_tag="VH800_001453"
     CDS             11..715
                     /locus_tag="VH800_001453"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEQ8362515.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVTAGSFSK
                     RFGVEEGHVLETPIVEFYYKNDDLDDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            839..4564
                     /locus_tag="VH800_001454"
     CDS             839..4564
                     /locus_tag="VH800_001454"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEQ8362516.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIEALPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYQADDFATYKAEQGLAMEVDDLLFIQNYFKSIGCVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPNDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKDNFSQFEAIQAQHKIT
                     AASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKLVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQILFASAVKYFTGK"
     gene            4725..6179
                     /locus_tag="VH800_001455"
     CDS             4725..6179
                     /locus_tag="VH800_001455"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEQ8362517.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDRGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHSVDEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6207..7229
                     /locus_tag="VH800_001456"
     CDS             6207..7229
                     /locus_tag="VH800_001456"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEQ8362518.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYIATGKNNPVKLEEVVSGVAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAV
                     GVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVKAALPLIKEELVKGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     ASVVIK"
     gene            7397..7951
                     /gene="purN"
                     /locus_tag="VH800_001457"
     CDS             7397..7951
                     /gene="purN"
                     /locus_tag="VH800_001457"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEQ8362519.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKVAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYERRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8135..9682
                     /gene="purH"
                     /locus_tag="VH800_001458"
     CDS             8135..9682
                     /gene="purH"
                     /locus_tag="VH800_001458"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEQ8362520.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVTLDDAGV
                     ETIAIDDVTRFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYTYKADPVSIFGGIIVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9740..10864)
                     /locus_tag="VH800_001459"
     CDS             complement(9740..10864)
                     /locus_tag="VH800_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ8362521.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFIVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            11117..12382
                     /gene="purD"
                     /locus_tag="VH800_001460"
     CDS             11117..12382
                     /gene="purD"
                     /locus_tag="VH800_001460"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEQ8362522.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFANGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVEMIVRPVLEGMVAEGRPYLGVLYVGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPFDYEKGVPLPEKTDGDIITYYAGVKFSENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            12660..13151
                     /gene="purE"
                     /locus_tag="VH800_001461"
     CDS             12660..13151
                     /gene="purE"
                     /locus_tag="VH800_001461"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEQ8362523.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDLLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            13138..14211
                     /gene="purK"
                     /locus_tag="VH800_001462"
     CDS             13138..14211
                     /gene="purK"
                     /locus_tag="VH800_001462"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEQ8362524.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASDSPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IVEKDFLANKAGVTVAPYKVVTSSLDLGGLDLTKTYVLKTETGGYDGHGQKIIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGKDVTVFPVQENIHRNNILSKTIVPA
                     RISDQLADKAKKTAVQIAKKLQLSGTLCVEMFTTADDIIVNEIAPRPHNSGRYSIEAC
                     DFSQFDTHILGVLGAPLPQIQLHAPAVMLNVLGQHVQQATDYVAKNPSAHLHMYGKLE
                     AKHNRKMGHVTVFAKDADEVKEF"
     gene            14238..>14574
                     /locus_tag="VH800_001463"
     CDS             14238..>14574
                     /locus_tag="VH800_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HEQ8362525.1"
                     /translation="MANIQINRIKSKLTELFSSIIYMGNIKVDEDSEEYKKMWYSRAY
                     SAYSTFLLGAENVDEATKSVTDGFADNGIDAIYNDKNKKILYFIQTKFSNEANGSISE
                     GDTLKFIKGV"
BASE COUNT         4156 a         2877 c         3421 g         4120 t
ORIGIN      
        1 gaataatcaa gtgactaacc agcttattta taaaggaaaa gcgaaagata tttatagtac
       61 aaaagatgaa aatgtgatta gaacggtcta taaagaccaa gctactatgt tgaatggagc
      121 tcgtaaggag actattgatg gcaagggagc actaaataat cagatttcat ctcttatttt
      181 tgagaaatta aataaggctg gtgtggtgac acattatatt gagcaaattt caaaaaacga
      241 acaattgaat aaaaaagttg atattattcc acttgaggtg gtgttacgga atgtgacagc
      301 aggctcattt tcaaaacgtt ttggagtgga agaaggacat gttcttgaaa cgccaattgt
      361 ggaattttac tacaaaaatg atgatctgga tgatcctttt atcaatgatg agcatgtgaa
      421 gtttttgggt attgttaatg atgaggagat tgcttatctg aaaggagaga ctcgccgtat
      481 taatgaactc ttgaaaggtt ggtttgctca gattgggctt aacttgattg acttcaagtt
      541 ggagttcgga tttgatcaag aaggtacaat tatcttagca gatgaatttt cgcctgataa
      601 ctgtcgccta tgggataaga atggtaacca tatggacaag gatgttttta gaagagacct
      661 tggcaacctg acggatgtct atcaagttgt acttgagaag ttgatagcat tgtaactaga
      721 agaggaagga attgaatccg ttcgggaaac tccgaaaaaa agatggaact tactgaaatc
      781 tcaatttcag atgtcctcct attttccagt cgctcccttg tcggacttgg tatcttatat
      841 gaataaacgt atttttgttg agaaaaaggc tgactttggt attaaatcgg ctagtcttgt
      901 gaaagagttg acgcataatc tacaactgac ctctttgaag gctttgcgta ttgtgcaggt
      961 ctatgatgtc ttcaatttgg ctgaggattt gctggcgcgt gctgagaagc atattttctc
     1021 tgagcaggtg acagactgtc ttttgacgga aactgaaatc actgcggagc ttgataaggt
     1081 tgccttcttt gccattgagg cgcttcctgg tcaatttgac caacgtgctg ctagttcgca
     1141 agaagctttg ctattatttg gaagtgacag tcaggttaag gtcaatacag cccagctata
     1201 cttggtcaat aaggatatta cagaagcaga gcttgaagcc gttaagaact atcttttgaa
     1261 ccctgttgat tcgcgtttca aggacattac tttgccgctt gaagagcagg ctttctctgt
     1321 atctgataag acgatcccta atcttgattt ctttgaaact tatcaagctg acgattttgc
     1381 gacttataag gcagagcagg gcttggctat ggaggtcgat gaccttctct tcatccaaaa
     1441 ttatttcaaa tcaatcggat gtgtgccaac tgagactgag ttgaaagttt tggatactta
     1501 ctggtcagac cactgccgtc acacaacctt tgaaactgaa ttgaagaaca ttgatttttc
     1561 agcttctaaa ttccaaaaac aattgcagac aacttatgac aaatatatcg ccatgcgtga
     1621 tgagcttggt cgttctgaaa agccacaaac acttatggat atggcgacta tttttggtcg
     1681 ttatgagcgt gccaacggtc gtctggacga tatggaagtc tcagatgaaa tcaatgcctg
     1741 ctcagttgag attgaagtag atgttgatgg tgtgaaagag ccttggctcc tcatgtttaa
     1801 gaacgagact cacaatcacc caacagaaat tgagccattc ggtggagcgg cgacttgtat
     1861 cggtggtgct attcgtgacc cattgtcagg acgttcatac gtttatcagg ctatgcgtat
     1921 ttcaggcgca ggcgatatca cgactccgat tgcggaaaca cgtgctggta aattgccaca
     1981 acaagttatt tctaaaactg cggcgcacgg ctattcttca tatggtaacc aaattgggct
     2041 tgcgacaact tatgtgcgcg agtacttcca ccctggcttc gtagccaaac gtatggagct
     2101 tggagctgtg gttggtgctg cacctaagga aaatgtggtt cgtgaaaaac cagaagcagg
     2161 cgatgtggtc atcttgctcg gtggtaaaac aggtcgtgat ggtgtcggtg gtgcgacagg
     2221 ttcatctaag gttcaaacgg ttgaatctgt ggaaacagct ggcgcagagg tacaaaaagg
     2281 gaatgccatt gaagaacgta agattcaacg tcttttccgt gatggcaatg tcactcgtct
     2341 tattaagaaa tcaaatgact tcggtgcagg tggtgtctgt gttgccatcg gtgaattggc
     2401 tgacggtctt gaaatcgatt tggacaaggt gcctcttaaa taccaaggtc ttaatggtac
     2461 tgaaattgca atctcagaat ctcaagagcg tatgtcagtc gttgttcgtc caaatgatgt
     2521 ggatgccttc atcgcagcct gcaacaagga aaatatcgat gcagtcgttg ttgcgaccgt
     2581 tactgaaaaa ccaaatcttg tcatgacttg gaatggcgaa atcatcgttg atttggaacg
     2641 ccgtttcctt gataccaatg gtgtccgtgt cgttgttgat gctaaagtcg ttgacaagga
     2701 cttgacagtt ccagaagcac gcacaacatc agcagagaca cttgaagcag atacgcttaa
     2761 ggtcttgtct gacctcaacc acgctagtca aaaaggtctt caaactatct ttgactcatc
     2821 tgttggtcgt tcaaccgtta accacccaat cggtggtcgt taccaaatca caccgacaga
     2881 aagttctgtt caaaaattgc cagttcaaca tggtgtgaca acaactgcat ctgttatggc
     2941 tcaaggttac aatccttata ttgcagagtg gtcaccttat cacggtgctg cctatgctgt
     3001 cattgaagcg acagctcgct tggtagcaac gggtgctgac tggtctcgtg cacgtttctc
     3061 ttaccaagag tactttgagc gtatggataa acaggcagag cgttttggtc agccagtatc
     3121 agctcttctt ggttctattg aggctcagat tcaacttggt ttgccatcaa tcggcggtaa
     3181 ggactctatg tctggtactt tcgaagactt gacagtacca ccaaccttgg tagctttcgg
     3241 cgtgacaaca gcggacagcc gcaaggttct ctctcctgag tttaaagcgg ctggcgaaaa
     3301 catttactat atcccaggtc aagctatttc agaagatatt gattttgacc ttatcaagga
     3361 taactttagc cagtttgaag ctattcaagc tcaacataag attacagctg cctcagccgc
     3421 taaatacggt ggtgtcctag aaagtcttgc tctcatgact tttggtaacc gtatcggtgc
     3481 ttctgttgaa attgcagagc ttgacagcag cttgacagct caactcggag gttttgtctt
     3541 tacatcagct gaggaaattg ctgacgcggt gaaaatcggt caaactcagg cagactttac
     3601 agtcactgtc aatggaaatg accttgctgg cgctagcctt ctagcagcct tcgaaggcaa
     3661 attggaagag gtttacccaa cagaatttga gcagacagat gttcttgaag aagttcctgc
     3721 tgtggtatca gatactgtta tcaaggctaa ggaaacaatt gaaaaaccag tggtttacat
     3781 tccagtcttc cctggtacca actcagaata cgattcagct aaggcctttg aacaggttgg
     3841 agctagtgtc aacttggtac catttgtaac cttgaatgag gttgctattg ctgagtcagt
     3901 tgacactatg gttgctaata ttgctaaggc aaatatcatc ttctttgctg gaggtttctc
     3961 agcagcggat gaaccagatg ggtctgctaa gtttatcgtc aatatcttgc ttaacgagaa
     4021 ggtccgcgca gctattgaca gcttcatcga aaaaggtggc cttatcatcg gtatctgtaa
     4081 tggtttccaa gcccttgtta aatcaggtct tcttccatac ggaaacttcg aggaagctgg
     4141 tgagacaagt ccaactctct tctataatga tgctaatcag catgttgcca agatggttga
     4201 gactcgtatc gcaaatacca actcaccttg gttggcagga gttgaggtcg gcgatattca
     4261 tgccattcca gtttcacatg gtgaaggtaa acttgttgtc agcgcttctg aatttgcaga
     4321 gctaagagac aatggtcaaa tctggagcca atatgtggac tttgacggac aaccatctat
     4381 ggattctaaa tacaatccaa acggctctgt caatgccatc gaagggatta ccagcaagaa
     4441 tggtcaaatc atcggtaaga tgggacactc agaacgctgg gaagacggac tcttccaaaa
     4501 tatccctggt aacaaagacc aaatcctctt tgcaagtgct gtaaaatact ttacagggaa
     4561 gtaaaaaggt tcagtgaacc tttttagccc tcgccttgaa ttagtgaagg gcgaggttag
     4621 aaagaatctc gcttaatttt tgagaaatag taaacacggg cgataagttg tgcgaaaaac
     4681 tttctatttt cgctttactt gacagccttt gtatcgaggt aaaaatgaca tacgaagtaa
     4741 aatctctaaa tgaagaatgt ggagtctttg gtatctgggg acatcctcag gcagctcaag
     4801 tcacttactt tgggcttcat agccttcaac atcgcggtca agaaggagct ggtattgttt
     4861 caaatgacaa tgggaaactc tatggttatc gaaatgttgg gctcctttct gaagttttta
     4921 agaatcaatc tgaattagat aatttaactg ggaatgcggc tattggacat gttcggtatg
     4981 ctactgcagg ttctgcagat attcgcaata ttcagccttt tctttataaa tttcatgacg
     5041 ggcaatttgc tttatgccat aatggtaatt tgacaaatgc tatttcctta aggaaagaat
     5101 tagaaaagca aggtgcaatt ttcaatgcct cctcagatac tgaaattttg atgcacttga
     5161 ttcgtcgaag ccataactca agtttcatgg gaaaggtaaa agaagctcta aatacagtaa
     5221 agggtggctt tgcctatcta ctgatgacag aaaataaact cattgctgct cttgacccta
     5281 atgcctttcg tcctttgtca attggacaaa tgcaaaatgg tgcctgggtt atttccagtg
     5341 agacctgtgc ttttgaggtg gtaggcgcaa aatgggttag agatgttgaa cctggcgaag
     5401 ttattcttat agacgatcgt ggtattcaat gtgatcgtta tactgatgaa acgcaactgg
     5461 caatttgttc gatggaatat gtctattttg caaggccgga ttcaactata catggtgtta
     5521 atgttcatac ggctcgaaaa aatatgggaa agcgtcttgc acaagaattt aaacaggatg
     5581 ctgatattgt aattggtgtc ccaaattcgt ccttatcggc tgctatgggc tttgctgaag
     5641 aatccggatt accaaatgag atgggtcttg taaaaaatca gtatacgcag cgaaccttta
     5701 ttcaaccgac acaagaatta agggaacaag gtgttcgaat gaaactatca gcggtatccg
     5761 gtgttgtcaa aggaaagcgc gttgttatga ttgatgactc aattgtaaga ggaacgactt
     5821 ctagaaggat tgtcggatta ttaagagaag caggagctag tgaagtacat gttgctatag
     5881 ctagtccaga attaaagtat ccttgttttt atggtattga tattcagact cgtcgtgagt
     5941 tgatttcagc caatcactct gttgatgaag tgtgtgatat tattggcgca gatagtctga
     6001 cctatctctc actggatggg ttgattgaat caattggact cgaaacaaaa gcaccaaatg
     6061 gtggtttatg cgtagcttac tttgatgggc attatccaac accgctttat gattatgaag
     6121 aagaatacct cagaagttta gaagagaaaa caagttttta tattcaaaaa gtgaaataag
     6181 ctctgctaat tatataagga gaaaacatgt ctgaaaaaaa tgcttatgca aaatctggtg
     6241 ttgatgttga agctggttat gaagtggttg aaagaataaa aaaacacgtt gctcgtacag
     6301 aacgtgcggg agtcatggga gctctaggtg gctttggtgg gatgtttgac ttgagtaaaa
     6361 caggagttaa agagcctgtc ttggtttcag ggactgacgg tgtcggaaca aaacttatgc
     6421 ttgctatcaa gtacgacaag cacgacacaa tcggtcaaga ctgtgttgcc atgtgtgtca
     6481 atgatattat tgcagcaggt gctgagccat tatatttttt agattatatt gcgacaggaa
     6541 aaaataaccc agtcaaactt gaagaagttg tttctggtgt tgcagaaggt tgtgttcaag
     6601 caggagcagc actcattgga ggtgagaccg ctgaaatgcc tggaatgtat ggtcaagatg
     6661 attatgacct tgcaggcttt gctgttggtg tggctgaaaa atctcaaatc atcgacggtt
     6721 caaaagtaaa agaaggcgat attcttttgg gacttgcttc aagtggtatc cattcaaacg
     6781 gttattcttt ggtacgtcgt gtctttgctg actatactgg taaagagctg cttccagagc
     6841 ttgaaggcaa acaacttaag gatgtcctcc ttgagccaac tcgtatctat gttaaagcag
     6901 ctctgccatt aatcaaggaa gaactagtca aaggtatcgg ccacatcacg ggtggtggct
     6961 ttatcgagaa tattcctcgt atgtttgcgg atgatttggc tgcggaaatc gatgaggaca
     7021 aggtgccagt gcttccgatt ttcaaggcgc ttgaaaaata tggtgacatc aagcacgaag
     7081 aaatgtttga aatcttcaat atgggtgtcg gtcttatgct agctgttagt cctgaaaatg
     7141 ttaaccgcgt caaagagctc ttggatgaac cagtttatga aatcggtcgt atcatcaaga
     7201 aagcagacgc tagtgtggtg attaaataag tcactaaatt ttataagaaa ggagtgttta
     7261 gttagtttgc ctaactgaac acgggattaa atttctagga aaaaagataa aatgacttag
     7321 acgcaagcgt cgttgttcgt tttcctattt ttctacgaaa tttttcggca agccgaatca
     7381 tccctttgta tcgaatatga aaatcgctgt ttttgcttct ggtaatggtt ccaactttca
     7441 ggtcatagca gagcagtttc cagttagttt tgtcttttca gatcatcgtg atgcctatgt
     7501 tttagagcgt gctcagaatt tagccattcc aagcttcgct tttgaactca aggagtttga
     7561 gaataaggtg gcttacgagc aagccatcgt tgatttgttg gacaaacacg agattgactt
     7621 agtctgtctg gcaggctata tgaagattgt tggagaaacc ttactcttgg cctatgagag
     7681 gcgtattatc aatattcacc cagcctacct gcctgaattt ccaggtgccc acggtatcga
     7741 ggatgcttgg gaagctggtg ttgaccagtc tggcgtgacc atccactggg ttgactctgg
     7801 tgtggatacc ggtcaggtca tccaacaagt gcgcgtgcca cgcctagcag acgatagcct
     7861 agaaagcttt gaaacccgta tccatgaaac cgaatatcaa ctctacccag ctgtcttaga
     7921 tagcttggga gtggagagga aagtaatcta gcctttatct taaaatttta ggtaaagtta
     7981 ggaaagatag taaagaagaa ttaacgttcc aaaaagaaag gaattgaacc cgtctggaag
     8041 gcacagaaaa aagataaaca tctcctaggc gcaagcgtct tcgtcgagtt tcctattttt
     8101 ccttggcctt ctagtcggac ttggtatctt aaatatgact aaacgtgctt taatctcagt
     8161 gtctgacaag tcaggaattg ttgactttgc aaaagaattg aaaaacttgg gttgggatat
     8221 tatctcaact ggtgggacta aggttaccct tgacgatgct ggtgttgaga ccattgccat
     8281 cgacgatgtg actagattcc cagagatgat ggacggtcgt gttaagaccc tccacccaaa
     8341 cattcacggt gggcttttgg ctcgtcgcga cgctgacagc caccttcagg ctgctaagga
     8401 caacaatatc gagctgattg acctcgtggt tgtcaacctc tatcccttca aggagactat
     8461 ccttcgtcca gacataacct atgatttggc ggtggaaaac atcgacatcg gcggtccatc
     8521 aatgcttcgc tcagccgcta aaaatcacgc tagcgtgacc gttgtggttg acccagcgga
     8581 ttatgcgact gttttgggag aattggctga cgctggtcag acgacatttg aaacgcgtca
     8641 acgcttggca gctaaggtct ttcgtcacac agcagcctac gacgctttga ttgctgagta
     8701 cttcacaact caagtgggag aggctaagcc tgaaaaatta accatcactt acgaccttaa
     8761 acaggctatg cgttacggag aaaatccaca acaagacgct gatttctatc aaaaagcctt
     8821 gccaacagac tactcaattg cttctgctaa acagctcaac ggaaaagaat tgtctttcaa
     8881 taatatccgt gatgccgatg cggcaatccg tattatccgc gatttcaaag accgtccaac
     8941 tgttgttgct ctcaaacaca tgaacccatg tggtatcgga caggctgatg acattgagac
     9001 tgcttgggat tacacttata aagctgaccc agtttcaatc tttggcggaa ttattgtcct
     9061 taaccgtgaa gttgacgcag cgacagccaa gaagatgcac cctatcttct tggaaatcat
     9121 catcgcacca tcatactcag aagaagcgct agctattctc acaaataaaa agaaaaactt
     9181 gcgaatcctt gagttgccgt ttgatgccca agctgccagc gaagtggaag ctgagtacac
     9241 tggcgtagtt ggtggacttt tggtgcaaaa ccaagacgtt gtggctgaaa atccatctga
     9301 ctggcaagtg gtgacagacc gccaaccaac agaacaagag gcgactgccc ttgagtttgc
     9361 ctggaaggct atcaagtatg ttaagtctaa cgggattatt attactaacg atcacatgac
     9421 gcttggactc ggtgcaggtc aaaccaaccg tgtcggctca gtcaagattg ctatcgagca
     9481 ggctaaagac caccttgacg gtgccgttct agcatcagat gccttcttcc catttgcgga
     9541 caacattgaa gaaatcgctg ccgcagggat caaagcaatc atccaaccag gtggttcagt
     9601 tcgtgaccaa gactctattg acgccgcaaa caaacatggc ttgaccatga tcttcacagg
     9661 tgtgagacat tttaggcatt aataaaaaaa tgtggtctaa ttaaaaccac attttttatt
     9721 aaaagaaaat ataagttaac tataatttgt tagctttatc agcatttacc catgttccac
     9781 gagatccgat ttgaacataa ataccattac ttggttgatc aatttttaat actttataac
     9841 taccagtgac gataaaatat tcacccacac ggagaatttg atctcctaaa acttttcctt
     9901 ggttatctgt ttcatctaat ggtgtgggat caatccagtt tagtggagtt gggtctcctc
     9961 cggctaattc tttattaacg atcaaattat taacaagctg atctacacga aaaacgccag
    10021 ggaaggtaac agtatcaccg accttaatgg aaggttttgt attgtcattt tgaaccacag
    10081 actgtgcggg ctctttaatg ggaatatagc gtcggtttcc agaaaaactg aggtagctaa
    10141 gccatgtata acctccagca gtcacgactt tatcgtaata aacagattga cctgcttcat
    10201 agtaagcaag atcagggcta tcgatactgg tttgtccttt gactggtaat ctggttgtaa
    10261 agtgataagt tccagagggg tcaaatgaag cttgagaaat gtgttttagt tgtcttgggt
    10321 aggaatgact tgtctgagat gataagtctt taaaatggat ataaccactt acctgagatt
    10381 ttggaatttg acgcttatgg tatctttcag ggccttgtcc agcgttgtaa ttatactctt
    10441 cgatagtgac agtgtctcca cggatatcag ctacccatgc tacatgaccg taagcagcat
    10501 ttgactgata agcgttttta tcaaaccaag cgatagcccc tatgcttggt gtcttattca
    10561 caggataacc ctgatttttc gcgatatgtc cccacgtgca ggcattaccg tagcctttag
    10621 gtaactgaaa accattagca gagcttaaac gaaaagctgc aaaagaagtg cattggcgga
    10681 tatacatgtt ccacgaatcg attccattgc cttttttcca cttactcgga tagttatcgc
    10741 ctaaaacagc tgcatgaaca agattttcct gttgcgaaat aagtgtagat ggcatagtag
    10801 gtactagacc attaaaacct aaaaggatta ctcctgagac caaaaaacga tgaaattttt
    10861 tcattaatta cctcctgtaa cttattattc gaaagcaaga aacaaaaaat gttattttta
    10921 gatgattatt ttgaaaattg gctttacttg atattaaata actgtttgat tggctaatag
    10981 agtgttcctt atttcaagaa ttgtggtcta ctatcacatt tttacaatgt ttcaattatt
    11041 gataactaat acattatgta aaaaagcgaa cgtttatgat ataatatcta attataatac
    11101 gaaagaggtg gatgttttga aattacttgt tgttggttca ggtggtcgtg aacatgcgat
    11161 tgctaagaag ttgttagcgt ctaagggtgt ggatcaggtt tttgtggcac ctggtaatga
    11221 tggtatgacc ttggatggtc tggacttggt gaatatagta gtttccgaac attccaggtt
    11281 gattgccttt gctaaggaga atgagatttc ttgggccttt attggtcctg atgatgcgct
    11341 agcagctggt atcgttgatg atttcaacag tgctggactc agagcttttg gtccaacaaa
    11401 ggcagcagcg gagctagagt ggtcaaaaga ctttgccaag gaaatcatgg tcaaatacaa
    11461 tgtcccaaca gcagcctatg gcacattttc agactttgaa aaagccaaag cctacatcga
    11521 agagcagggc gcacctatcg tggtcaaggc tgatggcttg gcgctaggta agggtgtggt
    11581 cgtggctgaa accgttgagc aggcggtaga ggcggcgcaa gagatgcttc tggacaataa
    11641 gtttggcgat tcaggagcgc gtgtggttat cgaggaattc ttggatggcg aggagttttc
    11701 cctctttgcc tttgctaatg gcgataagtt ctacatcatg ccgacagctc aggatcacaa
    11761 gcgtgccttt gacggagaca aggggccaaa cactggtggt atgggtgcct atgcgccagt
    11821 tcctcatcta cctcagagcg tggtagacac agcggttgag atgatcgtta ggcctgtcct
    11881 tgagggcatg gttgccgaag ggcgtcctta tctaggtgtc ctctatgtgg ggcttatcct
    11941 gacagctgat ggacctaagg ttatcgagtt caactcacgt ttcggtgacc ctgaaactca
    12001 gattatcctc cctcgcctga cttctgattt cgctcagaat attgacgata tcatgatggg
    12061 cattgagcct tacatcactt ggcagaagga cggtgtgact ttgggtgttg tcgttgcctc
    12121 agaaggctat ccattcgatt atgagaaagg tgtgccactg cctgaaaaga ccgacggcga
    12181 tatcatcacc tactacgcag gagttaagtt ttcggaaaat agcgagctac ttctctcaaa
    12241 cggaggacgt gtctatatgc tcgtcaccac agaagacagc gtcaaagcag ggcaggacaa
    12301 aatctatacc caactggccc aacaagacac aacaggtctc ttctaccgaa atgatatcgg
    12361 aagcaaagct ataagagaat aagactaacc attcaaatat tagcgtcagc aatcagcgac
    12421 cgaaggtcgc tccaaaaaga aagaagaaag gaactgaaca cgggactaat ttcccaggaa
    12481 aaaaataaaa ctacctggac gcaagcgtca tcgttagttt tctgcgtcgt aggcgtctga
    12541 tgctaaagca cctagtcgcc ctgacgtggg ttcgtcttcg aaatcaaaga tttcggactt
    12601 acctcatatt tttctacgga aagtttcgac aagtcgaaac gcccctttgt atcttaatta
    12661 tgaaaactcc aattatttct attatcatgg gctccaaatc tgactgggca accatgcaaa
    12721 aaacggctga agttctagac aactttggca ttgcttacga gaagaaagtc gtctctgccc
    12781 accgtacgcc agacctcatg ttcaagcatg ctgaggaagc acgtggtcgt ggcatcaaaa
    12841 tcatcatcgc aggagcaggt ggggcagctc acttgcctgg tatggtggca gctaaaacaa
    12901 cgctgcctgt tatcggtgtg cctgtcaaat cacgtgccct ttcaggtttg gatttgctat
    12961 attccattgt gcagatgcct ggcggtgtgc ctgtggcaac catggctatc ggagaagcgg
    13021 gagcgactaa cgctgccctg acagccctcc gtatcctctc tatcgaggac caaaatctgg
    13081 ctgatgcgct agctcatttc catgaggaac aaggaaaaat cgcagaggag tcaagtggtg
    13141 aactcattta agaccattgg gattatcggt ggtggtcagc tggggcagat gatggccatt
    13201 gcggctatct atatgggtca caaggtcatc acgctggatc ctgctagcga cagccctgcc
    13261 tcccgcgtta gcgaggtaat tgtggcgcct tacgatgatg ttgaggcttt gggacaattg
    13321 gctgcgcgtt gcgatgtgtt gacttatgag tttgagaatg ttgatgcgga cggtttggat
    13381 gccgttgtgt cagcttgtca gctaccgcag gggaccgatc tgctccgcat ttcccaaaac
    13441 cgtatcgttg aaaaagactt tctggcaaat aaggctggtg tgacagtcgc tccctataag
    13501 gtggtgacgt ctagccttga cctagggggg cttgatttga ccaagaccta tgtcctcaag
    13561 acagagacag gtggttatga cggtcatggg caaaagatta tccgctcagc agaagatttg
    13621 ccagaggcgc agcaattagc taactcagct cagtgtgtct tggaagagtt tgtcaacttt
    13681 gaccttgaaa tctcagtcat cgtgtctgga aatggcaagg atgtgacggt ctttcccgtt
    13741 caggaaaata tccaccgcaa caatatcctg tcaaaaacca tcgtaccagc tcgcatctca
    13801 gatcaactgg ctgataaggc taagaaaacg gcggtgcaga ttgccaagaa actccagctg
    13861 tcaggaactc tctgtgtgga aatgtttacg accgcagatg atatcattgt caatgaaatt
    13921 gccccacgcc cccacaactc agggcgctat tctatcgaag cctgcgactt ttcacagttt
    13981 gacacccaca tcttgggtgt gttgggcgca ccacttcctc agattcagct ccacgcccca
    14041 gccgtcatgc tcaatgtcct aggacaacat gtccagcagg caactgacta tgttgccaaa
    14101 aaccctagcg cccacctcca catgtatggt aaactagaag cgaaacataa ccgcaaaatg
    14161 ggacatgtga cggtgtttgc aaaagatgcg gatgaggtga aggagtttta aagagttaat
    14221 taggagatgt ttattttatg gcaaatattc aaataaatag aataaaaagt aaattgacag
    14281 aactgtttag tagtattatc tatatgggta atatcaaagt tgatgaggac tctgaagagt
    14341 ataaaaaaat gtggtatagt agggcttact cagcttattc aacttttcta cttggagcag
    14401 aaaatgtaga tgaagcaact aagtcagtta cggatggatt tgctgataat ggcatagatg
    14461 ccatctataa cgataaaaat aaaaaaattt tatattttat tcaaactaaa tttagcaatg
    14521 aagcaaacgg aagcatttct gaaggtgata cattaaaatt tattaaaggg gtta
//
LOCUS       DAUGJR010000043        13588 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUGJR010000043 DAUGJR010000000
VERSION     DAUGJR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13588
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.043"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(158..943)
                     /locus_tag="VH800_001464"
     CDS             complement(158..943)
                     /locus_tag="VH800_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362526.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGWEGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(953..1651)
                     /locus_tag="VH800_001465"
     CDS             complement(953..1651)
                     /locus_tag="VH800_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362527.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(1651..2022)
                     /locus_tag="VH800_001466"
     CDS             complement(1651..2022)
                     /locus_tag="VH800_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8362528.1"
                     /translation="MSWKFEEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            2207..5317
                     /locus_tag="VH800_001467"
     CDS             2207..5317
                     /locus_tag="VH800_001467"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEQ8362529.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEIEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYFCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDALTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDITAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSVTEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            5397..6410
                     /gene="pfkA"
                     /locus_tag="VH800_001468"
     CDS             5397..6410
                     /gene="pfkA"
                     /locus_tag="VH800_001468"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEQ8362530.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKDGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            6473..7975
                     /gene="pyk"
                     /locus_tag="VH800_001469"
     CDS             6473..7975
                     /gene="pyk"
                     /locus_tag="VH800_001469"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8362531.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            8193..8750
                     /gene="lepB"
                     /locus_tag="VH800_001470"
     CDS             8193..8750
                     /gene="lepB"
                     /locus_tag="VH800_001470"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8362532.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            8926..10740
                     /gene="glmS"
                     /locus_tag="VH800_001471"
     CDS             8926..10740
                     /gene="glmS"
                     /locus_tag="VH800_001471"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEQ8362533.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKSLSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LAAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            10936..11271
                     /locus_tag="VH800_001472"
     CDS             10936..11271
                     /locus_tag="VH800_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEQ8362534.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            11377..12018
                     /locus_tag="VH800_001473"
     CDS             11377..12018
                     /locus_tag="VH800_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8362535.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLVSKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            12028..12657
                     /locus_tag="VH800_001474"
     CDS             12028..12657
                     /locus_tag="VH800_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362536.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            12673..13509
                     /locus_tag="VH800_001475"
     CDS             12673..13509
                     /locus_tag="VH800_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8362537.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGRCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         4280 a         2240 c         2820 g         4248 t
ORIGIN      
        1 agatgttata tcttggttct tacagcatta aggtttggtg ttaatttgat aaaccgcttc
       61 tatttgatgg aagacggttt ttttatttac tatgaacact gaaaaaaact ttcttttaaa
      121 ctatagtgtg tcatagttta aaagaaagtc ttaacgctta ctgtaggttg agtttatttt
      181 tgataataaa attagtggcg aggtaaaaca ttatcatttc aataaattgt tccaaaataa
      241 gaagataaat tgttttttgc tcagtaaatg ggaaactatc ggcacttgta ttaatattaa
      301 agatgtgact gtgaacatat gttgcagcaa cgctaatcag aataactaat ataaaatatg
      361 caataaaggc catcaagcct cgccgattgg aaaaaagttg acctatagaa atggaaagat
      421 aaattaataa gatactcgta aatgttgata ataggacata ggctagtaca gttagcatat
      481 tgatgaaata atccatctta aaactattaa agaatccttc taatagttcg ttgatgttaa
      541 acattggtac aattacaata gcgatagcaa atgcaaggat gatagtattg aaaacactgc
      601 aaataaaaga agctagtagt tttgataaaa taatttgatg cgaattgacg ggtaaagtca
      661 acgttaagta tccttcccat ccaaaaacac ttttgctgaa acgtttgata atgataagta
      721 atgttgataa gagggaacca gcgatcaggg agccaaaagt taaacctaat gtcagaggca
      781 acatcttatt ggttagtact ccaaatagtc catcactatt gctttgagca aacagtttta
      841 tcgtaaatga caaaatggca gcgatggcaa taacgaaagc attaagcgca aagtaccatt
      901 ttccaataga tctaaattcg tattttaata attttccaaa catgatatcc tcctaaacct
      961 tataagtttc cctaaagagg gaatcaatgg attgctggta ttcttgtctt agatcatcag
     1021 cattgccaga taagaaaagt cttccttgtt tcaagaaaat gacttcgtca aggataggtt
     1081 caatgtccga aatcaagtgg gttgagataa taacagaagc attttcacaa taactattaa
     1141 tgatggtttt taggatgtag tctcttgcgg cagggtcaac tccaccaata ggttcatcaa
     1201 gtacatagag tctggcttta cgactcatca caagaattaa ttgtactttt tctttgtttc
     1261 ctttggatag agttttgaag cggtcttcag ggtctagttc taaatctctt agaaggcttg
     1321 ttgctttgga tttgtcaaag tcgctgtaaa aatcactaaa gaactccaac atgtccttaa
     1381 ttctcatatt ttcattaaga taagtagtat ctggtaaata agaaataatt ttttttgtct
     1441 caacacaggg acggtagcca tcaatgacaa tttctccttt atttggttgt aaaaggccat
     1501 taatgagttt aattaaagtt gttttaccac ttccatttgg acctaataat ccgataattt
     1561 taccgttcgg gatagtaatg gttaagtcat caatagcttt tttttcacgg taagattttg
     1621 aaacatgatg tagttgcaat aggtgtgcca ttattgtgaa tcctccttta aaaagctcgt
     1681 caaaacaggg ataatctcag tgtgactaaa tcccattttt gtcatattgg tgataaatga
     1741 ttctaattca ctaattgcta actctcgtct tttacgagca attaattttt gatcgtcagt
     1801 tacaaaacgg ccagcagtac gttgcgaata aaccattcct tcccgttcaa gttctgtaaa
     1861 cgctcgttgc atggtgttag gattaacacc tgcgatttct gcatattcac gaacagttgg
     1921 aagttgatca ccactcttga tttcttggct aataatttgc atcatgacat gttgtgctat
     1981 ctgcgcataa ataggagatt tttcctcaaa tttccaagac atgtggtctc ctttctgagt
     2041 aatatagata tttgtactaa ttaaatggta cagaaaaaaa aagggaatgt caagttttat
     2101 gccatttttc actctttgag aagtagacgt agattagaga gaaaattgaa gcaagaaaac
     2161 ctttttcata gtataatagg gaacaagata accaaaggag gaacttatgt ttgctcaact
     2221 tgatactaaa actgtatact catttatgga tagtttaatt gacttaaatc attattttga
     2281 acgagcaaag caatttggtt accacaccat aggaatcatg gataaggata atctttatgg
     2341 tgcttaccat tttattaaag gttgtcaaaa aaatggactg cagccagttt taggtttgga
     2401 aatagagatt ctctatcaag agcggcaggt gctccttaac ttaatcgccc agaatacaca
     2461 aggctatcat cagcttttaa aaatttccac ggcaaaaatg tctggcaagc ttcatatgga
     2521 ttacttctgc caacatttgg aagggatagc ggttattatt cctagtaagg gttggagcga
     2581 tacattagtg gtcccttttg actactatat cggtgttgat cagtatactg atttatctca
     2641 tatggattct aagaggcagc ttatacccct aaggacagtt cgttattttg cgcaagatga
     2701 tatggaaacc ctgcacatgt tgcatgccat tcgagataac ctcagtctgg cagagacccc
     2761 tgtggtagaa agtgatcaag agttagcaga ttgtcaacaa ctaaccgcct tctatcaaac
     2821 acactgccct caagctctac agaatttaga agacttagtg tcaggaatct attatgattt
     2881 cgatacaaat ttaaaattgc ctcattttaa tagagataag tctgccaagc aagaattgca
     2941 agacttgact gaggctggtt tgaaggaaaa aggattgtgg aaagagcctt atcaatcgcg
     3001 cttactacat gaattggtca ttatttctga catgggcttt gatgattatt ttttgattgt
     3061 gtgggattta cttcgctttg gacgcagtaa aggctattat atgggaatgg gacgtggctc
     3121 ggcggcaggt agtctagtgg cttatgctct gaacattaca gggattgatc cagttcaaca
     3181 tgatttgcta tttgagcgct ttttaaacaa agaacgttat agcatgcctg atattgatat
     3241 cgatcttcca gatatttacc gttcagaatt tctacggtat gtccgaaatc gttatggtag
     3301 cgaccattcg gcgcaaattg tgaccttttc aacctttggc cctaaacagg ctattcgtga
     3361 tgttttcaaa cggttcgggg ttccagaata cgaactgact aatctcacta aaaaaattgg
     3421 ttttaaagat agcttggcta ctgtctatga aaagtcaatc tcttttaggc aggttattaa
     3481 tagtagaact gaatttcaaa aggcttttgc cattgccaag cgtatcgaag gaaatccaag
     3541 acaaacgtcc attcacgcag ctggtattgt gatgagtgat gatgccttga ccaatcatat
     3601 tcctctaaaa tcgggcgatg acatgatgat cacccagtat gatgctcatg cggtcgaagc
     3661 taatggcctg ttaaaaatgg attttttggg gttaagaaat ttgacctttg ttcaaaaaat
     3721 gcaagagaag gttgctaaag actacgggtg tcagattgat attacagcca ttgatttaga
     3781 agacccgcaa acgttggcac tttttgctaa aggggatacc aagggaattt tccaatttga
     3841 acaaaatggt gctattaatc ttttaaaacg gattaagcca caacgttttg aagaaattgt
     3901 tgccactacc agtctaaata gaccaggggc aagtgactat accactaatt tcattaaacg
     3961 aagagaagga caagaaaaaa ttgatttgat tgatcctgtg attgctccca ttttagagcc
     4021 aacttacggt attatgcttt atcaagaaca agttatgcag attgcacagg tttatgctgg
     4081 ttttacgtta ggcaaggccg acttgttaag gcgtgccatg tctaaaaaaa atctacaaga
     4141 aatgcaaaaa atggaagaag actttattgc ttctgctaag cacctaggga gagctgaaga
     4201 aacagctaga ggacttttta aacggatgga aaaatttgca ggttatggtt ttaaccgcag
     4261 ccatgccttt gcctattcag ctttagcttt tcaattggct tatttcaaag cccattaccc
     4321 ggctgttttt tacgatatca tgatgaatta ttctagcagt gactatatca cagatgctct
     4381 agaatcagat tttcaagtag cgcaagttac cattaatagt attccttaca ctgataaaat
     4441 tgaagctagc aagatttaca tggggctgaa aaatattaag gggttgccaa gggattttgc
     4501 ttattggatt atcgagcaaa gaccatttaa tagcgtagag gattttctca ctagaactcc
     4561 agaaaaatat caaaaaaagg ttttccttga gcctctgata aaaataggtc tgtttgattg
     4621 ctttgagcct aaccgtaaaa aaattctgga caatttggat ggtttactgg tatttgttaa
     4681 tgagcttggt tctctttttt cagattcttc ctttagttgg gtagatacga aagattactc
     4741 agtaactgaa aaatattctt tggaacagga gatcgttgga gttggcatga gcaagcatcc
     4801 tttaattgat attgctgaga aaagtaccca aacttttact cctatttcac agttagtcaa
     4861 agaaagcgaa gcagtcgtac tgattcaaat agatagcatt aggatcatta gaaccaaaac
     4921 aagtgggcag caaatggctt ttttaagtgt gaatgacact aagaaaaagc tcgatgtcac
     4981 actttttcca caagagtatg ccatttataa agaccaatta aaagaaggag aattctatta
     5041 cttaaaaggt agaataaaag aaagagacca tcgactgcag atggtgtgtc agcaagtgca
     5101 aatggctatt agtcaaaaat attggttatt agttgaaaac catcagtttg attcccaaat
     5161 ttctgagatt ttaggtgcct ttccaggaac gactccagtt gttattcact atcaaaaaaa
     5221 taaggaaaca attgcattaa ctaagattca ggttcatgta acagagaatt taaaggaaaa
     5281 acttcgtcct tttgttctga aaacggtttt tcgataaaaa tggacaatta gtgaagtatt
     5341 ttgcaaatga atgtgctata ataagaccgt taaattaatt aaaggagtac cagaaaatga
     5401 aacgtattgc tgttttaacc agtggcggcg acgctcctgg tatgaacgct gctattcgtg
     5461 cagtcgttcg taaagcaatt tcagaaggaa tggaagttta tggtatcaac cgtggctatg
     5521 caggtatggt tgatggcgac attttcccac tgggttcaaa agaagttggt gataaaatct
     5581 cacgtggtgg aactttctta tactcagctc gttatccaga gtttgctcaa cttgaaggtc
     5641 aattggctgg tattgagcaa cttaaaaaac atggtattga aggtgttgtt gttattggtg
     5701 gggatggttc ttatcatggc gctatgcgct tgacagagca cggcttccca gcggtaggta
     5761 tcccaggaac aatcgataac gatattgcgg gaactgacta cactatcgga tttgatacag
     5821 cagttaacac agcagttgaa gctattgata aacttcgtga cacctcatca agtcacggac
     5881 gtacttttgt ggttgaagtg atgggtcgca atgcgggtga tattgctctt tgggcaggta
     5941 ttgctagtgg tgctgatcaa atcattgttc cagaagaaga gtttgatatt gaaaaagtgg
     6001 catcaacaat ccaatatgat tttgaacaca aaggtaaaaa tcaccacatt atcgtcttag
     6061 ctgaaggtgt tatgagcggt gaagcttttg ctcaaaaact gaaagaagct ggcgataaga
     6121 gtgaccttcg tgtgacaaat cttggccaca ttcttcgtgg gggttcacca actgctcgtg
     6181 accgtgtcat tgcttcttgg atgggttcac atgctgttga gctacttaaa gatggcaaag
     6241 gtggtttggc tgttggtatt cacaatgaag aacttgttga aagcccaatc cttggtactg
     6301 cagaagaagg tgctttgttc agcttgactg aagaaggcaa gattattgtt aataatccac
     6361 acaaagctcg tttagacttt gcagctttga accgttcatt gtcacaataa gtttagttaa
     6421 aattgttaaa tcgtcaatta ttgacaaaaa aataagggag tttcagagta aaatgaataa
     6481 acgcgtaaaa atcgttgcaa cacttggtcc tgcggttgaa atccgtggtg gtaaaaaata
     6541 cggagaagat ggctactggg ctggtcaact tgatgttgaa gaatcagcaa aaaaaatcgc
     6601 tgaattaatt gaagctggtg cgaatgtttt ccgtttcaat ttctcacacg gtgaccacaa
     6661 agagcaaggt gaccgtatgg caactgttcg ccttgcagaa gaaattgctc gtcaaaaagt
     6721 tggtttcctt ttggatacta aaggtcctga aatgcgtacg gaattgtttg cagatgatgc
     6781 taaagagttt agctatgtta ctggagaaaa aatccgtgta gcgactacac aaggtattca
     6841 atcaactcgc gatgttattg ctttgaacgt tgctggtagc cttgacatct acgatgaagt
     6901 agaagtaggt catactattc ttatcgatga tggtaaactt ggtttgaaag tgatcgacaa
     6961 agatatcgca acacgtcaat ttatcgttga agtagaaaac gacggtatta ttgctaaaca
     7021 aaaaggtgtt aatatcccta acactaaaat tcctttccca gcacttgcgg aacgcgacaa
     7081 tgctgatatc cgttttggtc ttgaacaagg acttaacttt attgcaatct catttgttcg
     7141 tacagccaaa gacgttgagg aagttcgtga aatctgtcgc gaaactggta acgaccatgt
     7201 gcaattattt gctaagattg aaaaccaaca aggtatcgat aatcttgatg aaatcatcga
     7261 agctgctgat ggtatcatga ttgcacgtgg cgacatgggt atcgaagtac catttgaaat
     7321 ggttccagtt ttccaaaaaa tgattatcac taaagtgaat gcagctggta aagcagttat
     7381 cacagcaaca aacatgcttg aaacaatgac tgaaaaacca cgtgcgacac gttctgaagt
     7441 atctgacgtc ttcaatgctg ttatcgatgg tactgatgca acaatgcttt caggagagtc
     7501 agctaacggt aaatacccgg ttgaatctgt tcgtacaatg gcgactattg atcgtaatgc
     7561 acaaactctt cttaacgaat atggtcgttt agattcatct gccttcccac gtaccaataa
     7621 aacagatgtt attgcttcag ctgttaaaga tgccactcat tcaatggaca tcaaacttgt
     7681 tgtgactatt actgagacag gtaatacagc tcgtgcgatt tctaaattcc gtccagatgc
     7741 ggacatctta gctgtaacat ttgatgaaaa agtacaacgt gctttgatga ttaactgggg
     7801 tgttattcct gttcttgctg aaaaacctgc atctactgat gacatgtttg aagtagcaga
     7861 gcgtgttgct gtggaggcag gcttagttca atctggggat aatattgtta ttgttgctgg
     7921 tgttccagtt ggtactggtg gaacgaatac tatgcgtgtt cgtacagtaa aataaatgtg
     7981 ttataactat ttacctaaag gttagaaggc aatattctaa ccttttttga tatcaaaaat
     8041 atcatgttaa ttcactactg ttaatttact ttaatgagtc taagtttgta ttttatacag
     8101 aatgagtaac gtttattggt attgatcaaa aattgtttac tttttttcta gcttagaaca
     8161 tggtataata agacaataga ctaggagtta atatggtaaa gcgagatttt ataagaaata
     8221 tattattgtt attaattgtg attattgggg ctattttgtt gagaatcttt gttttttcaa
     8281 cttttaaagt ttctccagaa acagctaata cttatttaaa gagtggtgat ttagtcacaa
     8341 tcaaaaaaaa tattcagccc aaatataaag attttgtggt ttatagagtt ggaaaaaaag
     8401 attatgtcag tcgagtcatt gctgttgaag gcgatagcgt gacttatatg gacgatattt
     8461 tttacctcaa taatatggta gagtcacagg cttaccttga aaagatgaaa gcacattact
     8521 tgaatcatgc accgtttggc acattgtata cagatgattt tacagttgct accatcacag
     8581 ctgataagta tcaaaaagtt cctaagggga agtatcttct tttgaatgat aaccggaaaa
     8641 atacgaatga cagtcgtcga tttgggttaa taaatgcctc gcagattaaa ggtttagtga
     8701 cctttagagt tttgcctctc agcgattttg gatttgtaga agtagagtag ttgtcaggct
     8761 actctacttt ttttataatt agactatacc aattttatgt ttgacaagac attgtggata
     8821 ttatatactg taaacataat gtttttatcg gtataattag actataccaa ttattgaaat
     8881 tatgagagaa agtagcaagt taacgaactt gttaaggtaa ttaagatgtg tggaattgtt
     8941 ggagttgttg gaaatcgcaa tgcaacggat attttaatgc aaggccttga aaagcttgaa
     9001 taccggggtt atgattcagc aggaattttt gtggctaatg ccaatcaaac aaacttgatt
     9061 aaatcagtgg ggcggattgc tgatttgcgt gccaagattg gcattgatgt tgctggttca
     9121 acagggattg gtcacacccg ttgggcaacg catggccaat caacagagga taatgcccat
     9181 cctcacacgt cacaaactgg acgttttgta cttgttcata atggtgtgat tgaaaattac
     9241 cttcacatta aaacagagtt cctagctgga catgatttta aggggcagac agatactgag
     9301 attgcagtac acttgattgg aaaatttgtg gaagaagaca agttgtcagt actggaagct
     9361 tttaaaaaat ctttaagcat tattgaaggt tcctacgcct ttgcattaat ggatagccaa
     9421 gcaactgata ctatttatgt ggctaaaaac aagtctccat tgttgattgg acttggtgaa
     9481 ggttacaaca tggtttgttc agatgccatg gccatgattc gtgaaaccag tgaatttatg
     9541 gaaattcatg ataaggagct agttatttta accaaagata aggtaactgt tacagactac
     9601 gatggtaaag agctgatacg agattcctac actgctgaat tagacttatc tgatattggc
     9661 aaagggactt atcctttcta tatgctgaaa gaaattgatg agcaaccaac cgtaatgcgt
     9721 caattaattt caacttatgc agatgaaact ggtaacgtac aggttgatcc ggctatcatt
     9781 acctctatcc aagaggctga ccgtctttat attttagcgg cagggacttc ctaccatgct
     9841 ggttttgcaa caaaaaatat gcttgagcaa ttgacagata caccagttga gttgggcgtg
     9901 gcttctgagt ggggttacca catgcctctg cttagcaaga aaccaatgtt tattctacta
     9961 agccaatcag gagaaaccgc agatagtcgt caagttttag taaaggcaaa tgctatgggc
    10021 attccgagtt tgacagtaac taacgttcca ggatcaacct tatcacgtga agcaacatac
    10081 accatgttga ttcatgctgg acctgaaatt gctgttgcgt ctacaaaagc ttacactgca
    10141 caaattgctg cccttgcctt tttggctaag gcagttggtg aggcaaatgg taagcaagaa
    10201 gctcttgact ttaacttggt acatgagttg tcattggttg cccaatctat tgaggcgact
    10261 ttgtctgaaa aagatctcgc ggcagaaaag gttcaagctt tgctagctac tactcgtaat
    10321 gctttttaca tcgggcgtgg caatgattat tacgttgcga tggaagctgc tttgaaatta
    10381 aaagagattt cttatattca atgcgaaggc tttgcggctg gtgaattgaa acatggaacc
    10441 atttcattaa ttgaggagga cacgccagta atcgctttaa tatcgtctag tcagttggtt
    10501 gcctctcata cgcgtggtaa tattcaagaa gttgctgccc gtggggctca tgttttaaca
    10561 gttgtggaag aagggcttga ccgtgaggga gatgacatta ttgtcaataa ggttcatcct
    10621 ttcctagccc cgattgctat ggtcattcca actcaactga ttgcttacta cgcttcatta
    10681 caacgtggac ttgatgttga taagccacgt aatttggcta aagctgtaac agtagaataa
    10741 atgattataa tggataaggc aaccatctgt taggtggttg ctttttgttt ttaggagaat
    10801 agcagagctt agaaaatggc cttgagaaaa gctatacaag aagaatagtc atcttctgat
    10861 gagaacgtat tcatcttgtc aaatcattga ttctaaagta aaatggtaac attaagaaat
    10921 gtttaggagt gtaagatgtc attaccaaat tgtttgcaat gccagtctga atatgtttac
    10981 gaagatggtc ttttattaat ctgtccaatg tgtgcttttg aatggacacc aggcgaagaa
    11041 gcgactgaag aagaaggact tgttgttttg gatagcaatg gtgtccgact gtctgatggt
    11101 gataccatta ctgtggttaa agatttgaaa gtaaaaggcg ctccaaaaga cctgaaacaa
    11161 gggactcgag ttaaaaatat tcgcctggtg gaaggtgatc ataatattga ttgtaagatt
    11221 gatgggtttg gcgcgatgaa attgaaatca gaatttgtca agaaaatcta ataataatac
    11281 gcaaccagct gatctggttg tatttttata aaaaacctct ccccaaatac gttcaaattt
    11341 ggtataatag tgaaatattc agttttagga ggcaacatga cctatattca gcaagtttta
    11401 cccagcttat tagatggtgc cttggtgact ttacaagtat tctttattgt tatcattctt
    11461 tctataccct taggggctat tttagctttc ttgatgaaga ttccctttaa accgctacag
    11521 tggtttttga ccctatacgt gtggatgatg cgagggacac cattactact tcaattgatt
    11581 tttttctatt atgttttgcc aagtgtgggg attagttttg atcgaatgcc agctgctatt
    11641 ttggcgttta ctttgaatta tgctgcctac tttgctgaaa tttttagagg tgggattgag
    11701 gctattccaa aaggtcaata tgaagcagct aaagtattaa agttaaaacc tcttcaaacc
    11761 attcgttata ttattttgcc tcaagtgttt aaaattgtgt taccaagtgt tttcaatgaa
    11821 gtcattaatt tggtcaaaga ttcttccctt gtctatgtac tcggtgtagg agatctttta
    11881 ttagtaagta agacggcagc caatagggat gcaaccttag cccctatgtt tatcgctggt
    11941 cttatctatt tgcttttaat tggactggtc acgattattt caaaacaagt tgaaaaacgg
    12001 tttaattatt atcagtaagg aggcttcatg ttagaactca aaaatatttc caaacagttt
    12061 ggtcaaaaaa ccatttttga tggctttaat ctaaccgttc aagacggaga agtgctctct
    12121 ttggtaggcc catcaggtgg cggtaagaca acactcttac ggatgttggc tggtcttgaa
    12181 tctattgatt caggtcaagt cttttacaat ggcgaagatg ttggtattga tcatttggaa
    12241 aatcgtaact tgcttggatt tgttttccaa gattttcaat tgtttcctca tcttaccgtt
    12301 ttagacaacc taacgctgtc tccaacaatt acaatgggca agcaaaaggc tgacgctaaa
    12361 gaaaaggctt tggatttact ggcacgttta ggattaaaag aacatgccca agtttatccc
    12421 tattctttat ctggaggtca aaaacaacgg gttgctttgg caagagccat gatgattgac
    12481 cctcaaatta tcggttacga tgaaccgacc agtgctctag atcctgaact acgtcagacg
    12541 gtagaagcct tgattgttca aaaccgtgaa atgggaataa ctcaaattgt agtcactcac
    12601 gatcttgttt ttgccgaagc catctcagat cgtattatta gggttaatcc taaatagaag
    12661 aggacccaaa agatgattat aaaaaaaaga accgtagcaa ttttagccat agctagtagc
    12721 tttttcttgg tagcttgtca agctactaaa agtcttaaat caggagatgc ttggggagtt
    12781 taccaaaagc aaaaaagtat tacagttggt tttgacaata cgtttgttcc tatgggctat
    12841 aaggatgaaa gcggcagatg caaaggtttt gatattgatt tggctaaaga agtttttcac
    12901 caatatggac tcaaggttaa ctttcaagct attaattggg acatgaaaga agcagaacta
    12961 aacaatggta aaattgatgt aatctggaat ggttattcaa taactaagga gcgtcaggat
    13021 aaggttgcct ttactgattc ttacatgaga aatgaacaaa ttattgttgt caaaaaaaga
    13081 tctgatatta aaacaatatc agatatgaaa cataaagtgt taggagcaca atcagcttca
    13141 tcaggttatg actccttgtt aagaactcct aaactgctga aagattttat taaaaataaa
    13201 gacgctaatc aatatgaaac ctttacacaa gcttttattg atttaaaatc agatcgtatc
    13261 gatggaatat tgattgacaa agtatatgcc aattactatt tagcaaaaga agggcaatta
    13321 gagaattatc ggatgatccc aacgaccttt gaaaatgaag cattttcggt tggacttaga
    13381 aaagaagaca aaacgttgca agcaaaaatt aatcgtgctt tcagggtgct ttatcaaaat
    13441 ggcaaatttc aagctatttc tgagaaatgg tttggagatg atgttgccac tgccaatatt
    13501 aaatcttaaa aaggacactt gtcctttttt tgtttaacag gtgagatcta gcagacaaag
    13561 tcagctagac gatttaataa aaatctta
//
LOCUS       DAUGJR010000044        13565 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUGJR010000044 DAUGJR010000000
VERSION     DAUGJR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13565
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.044"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..984
                     /locus_tag="VH800_001476"
     CDS             <1..984
                     /locus_tag="VH800_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8362538.1"
                     /translation="RPKLQSSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTD
                     DLKPFQVKDLVSGHLERIQEEVEKKYPDAGFNSDKYNGLKESNSLLSDGFEVKSGNLI
                     FDKKLTIPLTTLFDVINPDFLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTP
                     QVLDILAKYQAKGTFFMIGSKVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQ
                     HQVNMTNQAIEKACGKKPRYLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGI
                     MTNVKNQLQPGGVVLMHDIHQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(1095..2180)
                     /locus_tag="VH800_001477"
     CDS             complement(1095..2180)
                     /locus_tag="VH800_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8362539.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFTNIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2278..2904
                     /gene="udk"
                     /locus_tag="VH800_001478"
     CDS             2278..2904
                     /gene="udk"
                     /locus_tag="VH800_001478"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEQ8362540.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            2984..3247
                     /locus_tag="VH800_001479"
     CDS             2984..3247
                     /locus_tag="VH800_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEQ8362541.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERKLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITCYTSILLTLLVTYIFMK"
     gene            complement(3300..4109)
                     /locus_tag="VH800_001480"
     CDS             complement(3300..4109)
                     /locus_tag="VH800_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEQ8362542.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            4254..4751
                     /locus_tag="VH800_001481"
     CDS             4254..4751
                     /locus_tag="VH800_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEQ8362543.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFTGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            4751..6421
                     /gene="dnaX"
                     /locus_tag="VH800_001482"
     CDS             4751..6421
                     /gene="dnaX"
                     /locus_tag="VH800_001482"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEQ8362544.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVAIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQVNLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            6516..6719
                     /locus_tag="VH800_001483"
     CDS             6516..6719
                     /locus_tag="VH800_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEQ8362545.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
     gene            complement(6694..7635)
                     /locus_tag="VH800_001484"
     CDS             complement(6694..7635)
                     /locus_tag="VH800_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEQ8362546.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFENGDLQTLRSGEISLSSWEN"
     gene            7839..10217
                     /locus_tag="VH800_001485"
     CDS             7839..10217
                     /locus_tag="VH800_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="internalin A"
                     /protein_id="HEQ8362547.1"
                     /translation="MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNMM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            10754..11950
                     /locus_tag="VH800_001486"
     CDS             10754..11950
                     /locus_tag="VH800_001486"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ8362548.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEAFESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLVTKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            12124..13383
                     /locus_tag="VH800_001487"
     CDS             12124..13383
                     /locus_tag="VH800_001487"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8362549.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT         4326 a         2339 c         2823 g         4077 t
ORIGIN      
        1 aggcctaaac tgcaatcttc tcacctaaga tcagttaaca ctttgactat ttctaaaata
       61 gtttatcaga aaaaattttt tcatttggct aaaaaatcag aaaaagttat aagtacatat
      121 cacgttacag acgacttgaa accgtttcag gtaaaggatc tagtatcagg acatttagaa
      181 agaatacaag aagaagttga aaaaaaatat ccagatgctg gttttaatag cgataagtat
      241 aatggcttaa aagaatctaa ttctttatta agcgatggct ttgaggtaaa atcgggaaac
      301 cttatttttg ataaaaagct aacgatacct ttgacgacat tatttgatgt tattaatcca
      361 gattttttag caaatagcga tagagctgcg tatgataatt ataggaccta caaagaacag
      421 catcccaaaa aactagttgc attaacgttt gatgatggtc cagatccgac gacgactcct
      481 caagttttag atattttggc aaaataccag gctaagggaa ctttctttat gataggttca
      541 aaggttgtga ataatgaaaa ccttactaaa cgtgttagcg acgctggcca tgaaattgct
      601 aatcatactt gggatcatcc taatctgact aatctttcag tcagcgagat tcaacatcaa
      661 gttaatatga cgaaccaggc tattgaaaaa gcttgtggca agaaacctcg ctatttacgc
      721 cctccatacg gagctacaaa tgcaactgtt cagcaatcct caggattaac acaaatgctt
      781 tggacggttg atacaagaga ttgggaaaat catagcactg atggcattat gactaatgtc
      841 aaaaaccaat tgcaaccggg aggagttgtt ttaatgcatg atattcatca aacaactatc
      901 aatgctttgc cgacagttat ggaatatcta aaagcagaag gatacgaatg tgtgactgta
      961 tcagaactct atgcgcatca gtaagtaata tcgttatgtt tctttagaat tgatatacta
     1021 aacaatccaa ttacttttga agtaattgga ttgttgtttt tagtagccct tgattaagtt
     1081 ttgtttttta acaactagtt gatgaaatga agttgttgat ttttgaggga gatttcagag
     1141 actttagcaa attttttcaa ttttttgagg tcttcagggt ggctaacaaa ggtaataacg
     1201 ataccagatt ttcccatacg gccggttcgt ccagctctgt gagtgtaatt ttccttatca
     1261 cgagcaacat caaaatgaat gacatagtca agattatcaa tatcaatgcc ccgagcaaca
     1321 agatccgtag ctaacaataa ggagagttgg tgggatttga atttttcgag aatggtttta
     1381 cggaatttga cattaatgtc actcgctaag gaaaccgcag cagctccatt atattggaga
     1441 cgttcttccg tagcacccaa atcagataaa ctgttgaaaa agaccaaagc tctaaaatga
     1501 ggaatattag taaattttcg taataaatct gtacgttcgc gcttgtcaac catgaggtaa
     1561 aaatgctgaa tagcatcgtt ggtttgctct gaaagatcga tgcagaatgt atttggagct
     1621 aaggaagttt gatccacctt attagtagca ctcatgtata ccatttgatg atctcgagga
     1681 acatagtggc taattttttg aacaaaatca tattgggaat cacctaatag ttcgtcatat
     1741 tcatctaaaa caatggtgtt gacagacatc atcttgattt ttttcaattt aatcagctca
     1801 aaaatgcgtc caggggttcc aatcaggatt tcaggacctt ttttgaggcg ttcgatttga
     1861 cgtttttgac tggttccaga aataaagagt tgtgccgtta agcctagtgg ctgtgcccaa
     1921 tcctttgtga cttcaaaaat ttggccagct aattcggtat taggggctaa aatgagtagt
     1981 tgttgggact ttttaggcgt cagtgccaat agactaggaa agacataagc taaggtcttg
     2041 cccgtcccag tagggctaat accaaggaaa tttttaccat caacaatagg ttgaaaggcc
     2101 tgttcttgga ttggcgttaa atgggtaaat gcaacttggt caagtttttc ttgccattga
     2161 gggggaaatt tagtgatcat gcgtcttcct tttactattg tttctatatt cattatagca
     2221 ttatagtctc aattttggta aaatagtgag aaagactttt tagatttgga gtttaaaatg
     2281 cttaaaaaac cgattattat tggtgtaact ggtggttcag gtggcggtaa aacaagtgtg
     2341 tcacgcgcta ttttggacag ttttccaaat gctcgtattg caatgattca acacgattct
     2401 tactataaag atcagtctca catgagtttt gaagaaaggg tcaagaccaa ttatgaccat
     2461 cctctagctt ttgatacaga ttttatgatt cagcaactaa aagaattatt agctggtaga
     2521 cctgtagata ttcctatcta tgattacaaa aagcataccc gcagtaatac gacctttcgt
     2581 caggatcctc aggatgttat tattgttgaa ggtattcttg tcctagaaga tgagcgtttg
     2641 cgagatttga tggatatcaa gctctttgta gacacagatg acgatattcg tattattcgt
     2701 cgtattaagc gtgacatgat ggaacgtggc agaagcttag aaagtattat tgatcagtac
     2761 acaagcgtgg taaagcctat gtatcatcag tttattgagc caagtaaacg ctatgctgat
     2821 attgttattc cagagggagt tagtaatgtc gttgctattg atgttattaa tagtaaaatt
     2881 gcgagtattc ttggagaagt atagtggaag tggctgagta gattatttaa atctgctctt
     2941 ttattgttgt gctcttcata gagaaaggga tcataaaata gaaatgttat taatttggct
     3001 tggattacta tttgtttgga atgaactcgt gtttgtcata tatgcctttg ataaaagaaa
     3061 agccataaaa aagaaacggc gtattagtga aagaaaatta ttagtgataa cagttttgtt
     3121 tggaggtttt ggagcattac ttgcagctaa aaagtaccac cataaaacca gaaagtggta
     3181 ctttgtcatc acttgttata ctagtatttt gttgacatta ctagtaactt atatctttat
     3241 gaagtgagtc acttaaaaga cccttaatca gtattattta gtcaaggctc ttttatagtt
     3301 taaaaaagca catcatcgtc aagggtgttg attttttgaa aaagatcacc aaagattaaa
     3361 aggattaatg ttcctagtaa aactgtcatg ccaggaatgc ttgttagagg agagttccag
     3421 atgaaatgta gaaccagagg acttaataac cagaaaattt gttgctgttt tgaaaaaagg
     3481 ttagaaccct ttaataataa gtatgctcca atggtaaaaa tagctgtatg tacccaatgt
     3541 gaagtcacag cagtgctaat acgttcaata gcagtcggta cgagactatc tatagatttt
     3601 gcttgaatca aataacggat atcttctgtt agttgaaagc ccatgccaga aagtaaagca
     3661 acaactaatt tttctttaag agtaagtcta ggaaataaag taattactaa aatagccgaa
     3721 gaagccttaa tgggctcttc gacaataggg gcagttaaag catctcccca aagctttaaa
     3781 gcgtctttag aagggatgat gtatgaccaa aattgtccta cgagatggtt cccacaagaa
     3841 gctaaaaaac ctgaaatata aagtccgcta agacagctaa caataataac gttcaggttc
     3901 atatgaaatt ttttacttaa ataaaaaata gctgctgcaa atggaattaa gtaaatgcct
     3961 aatagactaa tggttagtat tagagcaaaa gcttctttaa aggaaaggtt gttagcagtc
     4021 agtcctaaca attcaagttc aataccattt aaaactaaag caataaaaag accgtatcgt
     4081 aaccatttct gttgagtgat ttgtttcacg aaaacctcct aatattaaga tgatattaat
     4141 aatattgaaa attatatcat aaacaacctc aaaaaccatt ttaaaaacta actgaagcga
     4201 aagatagtcg taaaaaatac tcgaatagac ccagatatgc tataataaaa ggtatgaata
     4261 agtctaaaaa aattgagcaa taccaactaa tgatagcgca ggcaaaagag ctgtttgcga
     4321 atgaatcaaa tgctttggct aatttgtcaa atgccagcgc cctgttaaac atgacactac
     4381 ccaattctgt ttttacggga ttttaccttt ttgatgggca ggaattaatt cttggccctt
     4441 ttcaaggtag ggtttcttgc gtccatatca agcttggtaa aggtgtttgt ggcgaatcag
     4501 ctcagtctcg tcgaaccatt attataaatg atgtgaagca gcatgccaac tatatttcct
     4561 gtgatgcggc agccatgagt gaaattgttg tgcctatggt gaaagaaggc catttgattg
     4621 gggtgctgga cttggattct agtcttgtag ctgattatga tgaggttgat caagaatact
     4681 tagaggcctt tgtggatcta tttcttgaaa agaccacgtt tacctttaac atgtttggag
     4741 ttaaaaactg atgtatcaag ctctttatcg gaaataccgg agccaaacgt ttgacgaaat
     4801 ggtgggacaa tcggttattt ccacaacttt aaagcaggca gttgaatctg gcaagattag
     4861 ccatgcttat cttttttcag gtcctagagg gactgggaaa acaagtgcgg caaagatttt
     4921 tgcaaaggcc atgaattgtc ctaaccaagt cgatggtgaa ccctgtaatc aatgcgatat
     4981 ttgccgagat atcacgaatg gaagcttgga agatgtgatt gaaattgatg ctgcctcgaa
     5041 taatggtgtt gatgaaattc gtgacattcg agacaaatca acctatgcgc caagtcgtgc
     5101 gacttacaag gtttatatta ttgatgaggt tcacatgtta tcaacagggg cttttaatgc
     5161 gcttttgaaa actttggaag aaccgacaga aaatgttgtc tttatcttgg caacaacgga
     5221 attgcataaa attccagcca ctattttatc tcgtgtgcaa cgctttgaat tcaaagctat
     5281 taagcaaaaa gctattcgag agcatttagc ctgggttttg gacaaagaag gtattgccta
     5341 tgaggtggat gctttaaatc tcattgcaag gcgagcagaa ggaggcatgc gtgatgcttt
     5401 atctatttta gatcaggctt tgagcttgtc accagataat caggtcgcca ttgcaattgc
     5461 cgaagaaatt acaggttcta tttccatact tgctctgggt gactatgttc gatatgtctc
     5521 ccaagaacag gctacgcaag ctctggcagc cttagagacc atttatgata gtgggaagag
     5581 catgagccgc tttgcgacag atttattgac ctatctgcgt gatttattgg tggttaaagc
     5641 tggcggcgac aatcaacgtc agtcagctgt ttttgatacc aatttgtctc tctcgataga
     5701 tcgtatattc caaatgataa cagttgttac tagtcatctc cctgaaatca aaaagggaac
     5761 ccatcctcgg atttatgccg aaatgatgac tatccaatta gctcagaaag agcagatttt
     5821 gtcccaagta aacttgtcag gagagttaat ctcagagatt gaaacgctca aaaatgagtt
     5881 ggcacaactt aaacaacaat tgtcgcagct ccaatcgcgt cctgattcac tggcaagatc
     5941 tgataaaacg aaacctaaaa ccacaagcta cagggttgat cgggttacca ttttgaaaat
     6001 catggaagaa acggttcgaa atagccaaca atctcgacaa tatctagatg ctctaaaaaa
     6061 tgcttggaat gaaattctag ataacatttc tgcccaagac agagccttat tgatgggctc
     6121 tgagcctgtc ttagcaaata gtgagaatgc gattttggct ttcgaggctg cctttaatgc
     6181 agaacaagtc atgagccgaa ataatcttaa tgatatgttt ggtaacatta tgagtaaagc
     6241 tgctggtttt tctcccaata ttctggcagt accaaggaca gattttcagc atattcgtaa
     6301 ggaatttgct cagcaaatga aatcgcaaaa agacagtgtt caagaagaac aagaagtagc
     6361 gcttgatatt ccagaagggt ttgatttttt gctcgataaa ataaatacta ttgacgacta
     6421 aaactgaaat acataagggt aaggttttgc ccttacccac gttttatctc gttacttttc
     6481 ttcatagtac agtatttttt tgttataata aagctatgac tattcgacaa tttcttttta
     6541 tggcctttgt atgtgccttt gaaacctatt tttttaatga cctgttactc tctggaaatt
     6601 atctcttcgc cttattttgg ggcttgttgc tctttaggga tttaagaaga gtgcatacca
     6661 ttaaccaact gactaaaacc attttaaaaa cggctaattc tcccaagaag aaagactgat
     6721 ttcaccgctt cgcaaggttt gaaggtcacc attttcaaac tgtacaatga ggtgtccttg
     6781 atctgtgaga tcaatcgcaa tagcacgttt ttcttgacta ttttctataa aggtcacttg
     6841 tttattaaga acaagtgatt tttctttgta aactttgaca tggtccttga caggaataga
     6901 taagaataat ttccagatgt caatgataag gtcattgcgc gtgatagtcg gtttttcggt
     6961 aaagagagaa cctgcctttt gagcaatcgc ttctgggaag tcggtgacaa aaaagttgag
     7021 accaacccca ataatgacat cggtgattaa accagtttca acagaagtaa tggcttctgt
     7081 cagaatccct gcaactttat ggttacctag atagatgtcg tttacccatt tgatttctgt
     7141 atcaatgcct gttaatcgcg agatagcttt gacaatactg gaagcaacca tcatcgtata
     7201 aggaggcata tcagcataag ggacattggg ttttaggtac atggacatgt aaataccacc
     7261 ggtgctagct gaaaaaaatt gccgatcgag gcgtcctttg gcagcttctt ggctaggagc
     7321 taggtaaagc cttggagcgc tgttatgagc ttcgattcct tgtttggcat ctaattgggt
     7381 agattggctg tgaggggtat aggtgactgg catcccaagc ccttggctaa tggttttggg
     7441 taataaaata tcaccttgta ccatgcggta gcccttgtgt tttaaagaat caatttgaat
     7501 cccctgattt tcgagacttt tgatggattt ccaaacggat gtacgagaga tactgagttg
     7561 atctgctaga tattccccac tgacgaagtc atcggtttgt gacagtaatt gataaatttt
     7621 ttctgatgtt ttcatatgta tagtatatta taaaagatct tattttcaaa ggaaaagaaa
     7681 agttagtttt tttgtgtaat gctactaaca acagaaacta ttgtttgttg aagcttcaga
     7741 gctccaactc gtcaacaact aatagttatc ctaaaaagag cttgaggaaa aacaagtgat
     7801 gtgatatact taaccagtta aataaaaagg agggttgaat gaaaacgaaa aaagttatta
     7861 ttttagttgg tctattgtta tcatctcagt tgactttgat agcttgtcaa tcacgaggta
     7921 atggtacata tcccattaaa acgaaacaat cacgtaaggg aatgacgtca aacaaaatta
     7981 aaccgattaa aaaaagcaaa aagacaaaca agactcacaa aggtgtggcg ggtgtcgatt
     8041 ttcctacaga tgatgggttt attttaacca aagactcaaa aatcttatca aaaacagatc
     8101 agggaatcgt tgttgaccat gatggtcatt cgcattttat tttttatgcc gatttaaagg
     8161 gaagtccatt tgaatacctt attccaaaag gagcaagttt agctaagcca gctgttgctc
     8221 agcgagcagc tagtcaaggg acttctaaag tagcagatcc tcatcaccat tatgaattta
     8281 acccagcgga tattgtggct gaagatgctt taggctacac ggttcgccac gatgatcact
     8341 tccattatat tttgaagtca agcttatcag gtcagacaca ggcacaagct aaacaggttg
     8401 ctactcgctt gccacaaacc agtagccttg tttcaacagc tacagctaat ggtattccag
     8461 gcttgcattt cccaacctca gatggttttc aatttaacgg tcaaggtatt gttggggtaa
     8521 caaaagacag tattttagtg gaccacgatg gtcacttaca tcctatttct tttgcggacc
     8581 ttcgtcaggg tggctgggca catgtggcag atcaatacga tcccgctaaa aaagcagaaa
     8641 agccagcaga aacccatcag acaccagagc tatctgaacg tgaaaaggaa taccaagaaa
     8701 aattagctta tttggcagaa aaattgggga ttgatccatc aactattaaa cgtgtggaaa
     8761 cacaagacgg taaacttggt ttggaatacc ctcaccatga ccacgcacac gtattgatgt
     8821 tatctgatat tgaaatcgga aaagacattc cagatccaca tgctattgag catgcccgtg
     8881 aattggaaaa acataaggtt ggaatggata ccttgcgtgc cttagggttt gatgaagaag
     8941 tgattttgga tatcgttcgc actcacgatg ctccaacccc attcccatca aatgaaaaag
     9001 atccgaatat gatgaaagaa tggttagcaa cggttatcaa acttgacttg ggcagccgta
     9061 aagatccttt gcaacgtaaa ggactttcac tgttacccaa cttagaaact ttaggaattg
     9121 gctttacacc aatcaaagat atctcacctg ttttgcaatt taaaaaattg aaacagttgt
     9181 taatgacaaa aacaggggtg actgattata gatttttgga taatatgcca cagttagaag
     9241 gcattgatat ttcacaaaac aatctcaaag atattagttt cttgagcaaa tataaaaact
     9301 taactctagt agcggctgct gataatggta ttgaagatat taggccgctt ggtcaattac
     9361 caaatctcaa attcctcgta ttgagtaaca ataagatttc tgatttaagc ccactggcat
     9421 cgttacatca attgcaagaa ttgcacattg ataataatca gattacagat ttaagccctg
     9481 tttctcataa agaatcattg acggttgttg atttatcaag aaatgctgat gttgacttag
     9541 caacacttca agcacccaaa ttagaaacgt taatggtcaa tgataccaag gtttctcatt
     9601 tggatttctt gaaaaataat cctaatctat ctagcctatc tattaaccgt gcgcaattgc
     9661 aatctcttga aggtattgaa gcaagtagcg tcattgtcag agtagaagca gaaggtaacc
     9721 aaattaaatc gcttgtgctt aaagacaagc aagggtcact tactttcttg gatgtgacag
     9781 gcaaccagtt gacttctcta gaaggtgtta ataattttac agcacttgac attttaagcg
     9841 tgtctaaaaa ccaattaaca aatgtcaacc tatctaaacc caataagaca gttactaaca
     9901 ttgatattag tcataacaat atctcattag cagaccttaa attgaacgag caacatattc
     9961 cagaagccat tgcgaaaaac ttcccagcgg tttacgaagg ttctatggta ggtaatggaa
    10021 cagctgaaga aaaagcagct atggctacta aggcgaaaga aagtgctcaa gaagcatcgg
    10081 aatcacatga ctacaaccat aatcatacct atgaagatga agaaggtcat gctcacgagc
    10141 acagagacaa agatgatcac gaccatgaac atgaggatga aaatgaagct aaagatgagc
    10201 aaaaccatgc tgactaaact aatctaagaa taacccgatc caactgaatc gtcctaatga
    10261 caccattgtt gactatcaag agaacctcaa gaataacctt gaggtttttt tgaaataaat
    10321 aggataatga gtgaaaagaa tggcacctaa atggctaaaa catgttataa tagattgtta
    10381 ttgagtcccg ataagacggt ctgttgaacg aaatgttttt gagacgttgt tgacttcatt
    10441 tggggaacag tcgttctccc tttagctaaa ttacttcgtc taaggcttat tttgtggtga
    10501 catcctctca acaaggagac cggattcttt gtaactcaac gctattgtca gacattcttt
    10561 gtctggttaa tggacgctag ccactaggtg gactagctag ttgccttact agtaaaaccg
    10621 taactgatta gctaagttgg ttttggccac ttgacttgct caatcagcta ggaagaaagg
    10681 ggtaggcaac ttcttgcttt gtggtcaatg tgactgaaaa aggaagaatc aacatattag
    10741 gggggacatt tttatgtcag aacgtaaact tttcacgtct gagtccgtat ctgaagggca
    10801 tccagataag attgcagacc aaatttcaga tgctatttta gatgccattt tagcagaaga
    10861 tccagaagcc catgtggctg cagaaacttg tgtttacaca ggttctgttc atgtttttgg
    10921 agaaatctca acaacagcat acattgatat taaccgtgtg gtccgcgaca ccattgcaga
    10981 aattggttat acagaagcag aatatggctt ttcagcagaa tcagtgggag tacatccatc
    11041 acttgtagaa caatctggag atatcgctca gggggttaat gaagctttcg aaagcagaga
    11101 aggtgatact gatgacctta gccatattgg agcgggtgac caagggctca tgtttggttt
    11161 tgccatcaat gaaacaccag aattgatgcc tttaccaatt tccttatctc accaattagt
    11221 gcgtcgcttg gcggaattac gtaagtcagg tgagattagt tatctacgtc cagatgctaa
    11281 atctcaagtg acagttgagt acgatgaaca cgataaacct gttcgtgtgg atacagtcgt
    11341 tatttctact cagcatgatc cagaagctac taatgaccaa attcgtcagg atgtgattga
    11401 aaaagtgatc aaggctgtaa ttccagcaga ttatttagat gatgacacaa agttcttcat
    11461 taatccaaca ggacgttttg ttattggagg tccgcaagga gactctggat tgaccggacg
    11521 taagattatt gtggatacct atggaggcta ttcacgtcat ggtggcggtg ctttttcagg
    11581 aaaagatgcg acaaaagtgg accgttcggc ttcttacgct gctcgctata ttgctaaaaa
    11641 ccttgtggca gcaggccttg tgaccaaagc tgaagtccaa ctagcttatg cgattggggt
    11701 ggctcagcct gtgtctgttc gcgtggatac atttggaacc tcaacggttc ctgaagctgt
    11761 tttagaagct gctgttcgtc aagtctttga tttacggcca gcaggcatta ttcaaatgct
    11821 tgatttaaaa cgcccgattt acaaacaaac agctgcctat ggtcacatgg ggagaacaga
    11881 tattgatttg ccatgggagc gtttaaataa ggttgatgct ttagtagaag ctgtaaaaac
    11941 agtattataa acgacaactt tattaaaaaa gtagagtaag tgaaaaaatc ttactctgct
    12001 tttttgttat taaataagcc tttaaaaggg atgattaaaa attaagacgt caataattgt
    12061 caggcttcat gatttatgat aaaatgaaaa ggttgaattc tagtataaga aagttttgaa
    12121 tgtatgcgta aaattattat taatggcgga aaagccttat ctggagaagt ggcagtttca
    12181 ggggcaaaaa acagtgttgt tgcgcttatt ccagcaatca tcttagccga tgatattgtg
    12241 attcttgatg gtgtacctgc tattagtgat gtagatagtc tgattgaaat catggagctt
    12301 atgggagcaa cagtaaacta tcatggtgat actttagaaa ttgaccctag aggggtgcaa
    12361 gacatcccga tgccttacgg aaagattaat agtcttcgag cttcctatta tttctacggt
    12421 agtcttttag gtcgttttgg acaagcagtt gttggcttac ctggtggttg cgatttagga
    12481 ccaagaccaa ttgacttgca tttgaaggcc ttcgaggcta tgggagttga agtgtcttat
    12541 gagggtgaaa atatgaattt atcgacaaat ggtcaaaaaa ttcatggcgc tcatatctat
    12601 atggacaccg ttagtgtcgg tgctacaatt aatactatgg ttgcggcaac aaaagctcaa
    12661 ggtaaaacgg ttattgaaaa cgctgcacgt gagccagaga ttattgatgt ggctactctt
    12721 ttgaataaca tgggtgcgca tattcgtgga gcaggtacag atattattac gatacaaggt
    12781 gttcagaaat tgcatggtac tagacaccaa gttattcctg atcgtattga agcagggact
    12841 tatatcgctt tggcggcagc tattggaaaa ggtgttaaga tcactaatgt tctttatgag
    12901 catttagaga gtttcattgc taagttagaa gaaatgggtg tccgtatgac ggtagaagag
    12961 gatgctatct ttgttgaaaa gcaagaatcc ctcaaggcta ttacaattaa aacctctcct
    13021 taccctggtt ttgccactga tttgcaacag ccattaacgc ccttgttgtt aaaagcagat
    13081 ggtcgtggaa cgattattga cactatatat gaaaagcgca ttaaccatgt gccagagttg
    13141 atgcgcatgg gagcagatat ctcagttatt ggtggtcaaa ttgtttatca agggccgtct
    13201 cgcctgacag gagctcaggt caaagccact gatttacgtg ccggagcggc tctagtgact
    13261 gctggtctaa tagctgaagg caagacagaa attactaata ttgaatttat cttacgtggc
    13321 tatgctagta tcattgcaaa attaacagca ctaggggcag atattcaatt aatcgaagac
    13381 taaagagaag ctaacgcttc tcttttttat attacatgtg cttaggctaa tgatacttag
    13441 gtgcatactt tgttgcattt tatggctttt taactgtcat aaaaaagata aaaatgatat
    13501 cactaactaa tattattaat tttaatgcta aaataatgag ttgacggtag taaagtgata
    13561 aataa
//
LOCUS       DAUGJR010000045        13007 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUGJR010000045 DAUGJR010000000
VERSION     DAUGJR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13007
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.045"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            458..1966
                     /locus_tag="VH800_001488"
     CDS             458..1966
                     /locus_tag="VH800_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8362550.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVKLSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            complement(2315..3664)
                     /locus_tag="VH800_001489"
     CDS             complement(2315..3664)
                     /locus_tag="VH800_001489"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEQ8362551.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKDEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(4120..4824)
                     /gene="speG"
                     /locus_tag="VH800_001490"
     CDS             complement(4120..4824)
                     /gene="speG"
                     /locus_tag="VH800_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEQ8362552.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     PPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEAVRIKKKQFTLQEFDFKI
                     RKFLMEKYNIYDSESRYTSGSLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKI
                     FNSEEISHFDIYLKTH"
     gene            complement(4926..5024)
                     /gene="ffs"
                     /locus_tag="VH800_001491"
     ncRNA           complement(4926..5024)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VH800_001491"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            5224..6456
                     /locus_tag="VH800_001492"
     CDS             5224..6456
                     /locus_tag="VH800_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEQ8362553.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNIYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(7070..7585)
                     /locus_tag="VH800_001493"
     CDS             complement(7070..7585)
                     /locus_tag="VH800_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEQ8362554.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGVDSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(7585..8364)
                     /locus_tag="VH800_001494"
     CDS             complement(7585..8364)
                     /locus_tag="VH800_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8362555.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRNEFA
                     KLSIPDVSEGRAYDVTGVEQIGSFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PDGINSKNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(8504..9043)
                     /locus_tag="VH800_001495"
     CDS             complement(8504..9043)
                     /locus_tag="VH800_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEQ8362556.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLSAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(9047..9358)
                     /locus_tag="VH800_001496"
     CDS             complement(9047..9358)
                     /locus_tag="VH800_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362557.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCASCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSRAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(9575..10717)
                     /gene="tgt"
                     /locus_tag="VH800_001497"
     CDS             complement(9575..10717)
                     /gene="tgt"
                     /locus_tag="VH800_001497"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEQ8362558.1"
                     /translation="MTDYPIKYRLIKAEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            10936..11799
                     /locus_tag="VH800_001498"
     CDS             10936..11799
                     /locus_tag="VH800_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEQ8362559.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGSSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDEVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKN
                     PTPMMYDDQKD"
     gene            11996..13007
                     /locus_tag="VH800_001499"
                     /pseudo
     CDS             11996..13007
                     /locus_tag="VH800_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4060 a         2602 c         2310 g         4035 t
ORIGIN      
        1 aactagctct ctcaaaaaag attaaaaata aaggcattct aaagaatcat ttaagaaaac
       61 tttaaggtta ctatcgtaga atgaaaacat cctaaaaagc ggtttaccta aaccgttggg
      121 agaataggtt ttccccttgt tttccctttt cataaatctc ctgggcacct atcttcttag
      181 gtgccctccc ttgtttaaac ctgaccagtt aaccggctgg ttaggttttt aaatttaaaa
      241 agtcaacagc aaaaatatga tttcacccgc gtgttcttag ctctctcaat tatgggctaa
      301 aaacacgcat caatcaatct attgatgaag tttgctgctt tttgatgatc tttattgtga
      361 ctatactggt aatcctattg attttagttg acttttacgg tagattcgct acaatatata
      421 ggattataca atttaattta aggagagaaa aattacattg ttagattatt atttggaatc
      481 cgatattatt gaccagaaaa tcctactggc tattttgttg acagaaaaag aactgacgat
      541 ggcagcagct tgttctcaaa caactttgac tgctttaaaa ataaagcagt atcttcgaca
      601 atttaacgcc ttatttaaag ggtacttacg tattgagctt attaaatctc gtatttattg
      661 tgaggtatta aatgataagc gagaagcatt tttttatgac atttttgcct tatcagatac
      721 tctaaaaatg ttgacattct tattactaga taatcccaaa cacaaatcaa tcgctgttta
      781 tacacgaaaa caagggatat cccagtcaaa agcttatcgt cttattcata aattaaaaca
      841 ttatttacaa gacattggtt taaatattgt agacaatact gttatcggag atgaacttaa
      901 aatacggtat ttgattgctc ttttacataa agagtacggc attatattat atgatataca
      961 acctgcagac attgaaacga ttcatgcttt tatctttgca gcacaaaaaa acttacaacc
     1021 ttctgccttt ttagatagac gcttcttgtt ttttgatgtg ctgttgatgt tgacttggaa
     1081 gcgccatcgc tatcctgttc atttgcctca tttagctctt tttgaacatc tcaaatcctt
     1141 gcctattttt gacaatatca aaaccattgc cgtggatgag ctagcacctc gaactcgtgt
     1201 cacattttcg tctgatgatt ttgactatct ctttttaatt tatttaacga ctgataactc
     1261 cttcttgagt gggtactgga caagtcatca gcgacaacaa ctttaccatt taatcaccaa
     1321 agatcccgat tatcatttac taatccatcg tcttcaggca ctagttggaa aatattccga
     1381 tattcatgag catatcccta acttaattcc ttttttcaaa agaactctct acaatttaca
     1441 aactttaatt acctttgatg gttattattt tgatcaatat caaggcaaca tgctactact
     1501 agataagctt gaaaccgtta tcaaagattg gctttatgac acaggccgtc aaggcagtat
     1561 tagttctggt cacttacact tgatgtgttt ataccttgag cagatcttgg aaagctctat
     1621 tgctccaatc aatattactg ttattgagag ccaagaaact gttggtaacg ttatagctaa
     1681 tttcatcacc tcaactatcc cttcttacaa agttaaactg tcacgggtca atatcttatc
     1741 tgataatatt tatccctatg ataaacctgt agatctggtt gtaaccagtc agaagctctt
     1801 gcctttctta aaagaactcg gtgtttttcc caaagagacc cgcttgtttg gtttgagttt
     1861 ggactgtatc caacagcagc gcgaagattt aatcaaaacc atcttagcct tgcaccagaa
     1921 ccactaccaa aaacgtttag aagaactttg gagagttcct tcttaatttt ttgacagtcc
     1981 ctcctagata ctttcacagt ctaggagggt ctttaaggtt gtcacttgca accttgataa
     2041 gctctctttt tagccattgc tatttgctta gaaacagaac tggaactgtt atagcggttc
     2101 aactcctctt gtaggatctt cttccctttt ttgaaggtct tatctgaaat ttggtataat
     2161 aaagtgcgct cccatgttct ggaagcgcac tttattatcc cttttactta accttgtatc
     2221 cactcgatga tggaagtgcc gccccaattc ttagattgct tggctaactt ttaagctctt
     2281 gtacaaggaa gaagtctttt tgactatctg ttgattagag gcgagcatta agctctgctg
     2341 ataatgcttc aaaacctggt tttccaagaa gcgcaaacat gttacgtttg taagcttcaa
     2401 cacctggttg atcaaatggg ttaacagcat tcatgtagcc tgaaacagcg atggcaagct
     2461 caaagaagta aatagtgtaa ccaagggtaa actcgtcttg agctggaaga gtgacaaaca
     2521 tgtttggcac gccgccatct gtgtgggcaa gaagcacacc atctgtagct ttcttgttaa
     2581 cgaaatcaac gtctttacct tgaaggtaac caagtccatc taggtcttct gctaattcag
     2641 gaatgataac atttttacga ggattatcaa cacgaataac tgtttcaaag agattacggt
     2701 aaccttcttg gataaattga ccaagtgagt gaaggtctgt tgagaagtta gctgaagttg
     2761 ggtaaatccc tttttgatct tttccttctg attcaccagc taattgtttc caccattcgc
     2821 caaagtactg aagagatggc tcgtagttag ccaagatttc agtgatgtag cctttacggt
     2881 aaagcacatt acgaacagca gcgtattggt aagcaatgtt ttcagagatt ttgtctgaag
     2941 aaaggtcttt acgagcagca tttgcccctt ccataagagc agtaatatct gcacctgatg
     3001 cagcaattgg aagcaaacca acagcagtca agactgagaa acgaccacca acattatctg
     3061 gcaccacaaa tgtttcccag ttgttagcgt cagcttctac cttaacagca cccttaactt
     3121 tgtctgtggt agcgtagata cgtttgttag cttcttcttg gccatatttt ttaaccaaaa
     3181 gttctttgaa cacgcgaaag gcaatagctg gttcagtggt tgtacctgat ttagagatca
     3241 cgtttactga gaactctttg tcttgaacgt attcaactaa atcggcaagg taagtagatg
     3301 aaatagagtt tccagcgtaa agaatttgtg gggctttgcg ctctttggca gtttgcaagt
     3361 tagcaaaatg atgatttaaa aaatcaatcg ctgctttggc accaaggtat gacccaccga
     3421 taccgatcac cacaagaact tcgctgtctg ccttaatctt ttcagcagca gtcaagatac
     3481 gtgcaaattc atctttatca tagttttctg gaagatcaag ccagcccaag aaatctgaac
     3541 ctggtccagt tccttcacgc aataacttgt cagcttctgt tacttggcct tgtaaaaaat
     3601 caatttcatg ttgtcccgca aatgactcga ggacttttga ataatcaaat gtaatatgtg
     3661 acatgagttt cgctccctta aaattttaag tttcattagt atgataacct tttctatcta
     3721 atatttcaat ggtttttagt ggttttcacc tgtgaaaaag ctaggttttt tgaaaaggtt
     3781 ttcgtttttt cagacataaa acatgtgtca atgcaagcat attctcatca tagtggtttt
     3841 ttaagagaaa ataggatttc atatttccta aaaatatcat gaaaaaaggc cctgaggccg
     3901 ctttaccgta ataacttatt ttaaggattt tatcatttca acacgggtaa taaccccatc
     3961 atgcatatga tcaatgcata aagccacacc tacaaaggca attgaagccc caatcacctg
     4021 taaatacttt ctcatgctat cttcttaaca ttacttactc tcattatcta aaaatggcaa
     4081 tcatttgaat acttaaaaag caaagggggg agaatagcac tagtgcgttt ttaagtagat
     4141 atcaaaatga ctaatttctt cactattaaa aatcttatta tctttatacc ttttaaagaa
     4201 actgtctcga cttaaaagct tatcatcctt attaaataaa tcaacttcat aatgtttact
     4261 atctttagta gcaaggaaaa ggctccccga tgtataacgc gattccgaat catagatatt
     4321 gtatttttcc attagaaatt ttcttatttt aaaatcaaat tcctgtaaag taaactgttt
     4381 cttttttatg cgaacagcct cagagggcaa ataagtttct ttcccatctt gatttaaaat
     4441 tcctacaaac tgtaatgatt tatttccttg attcgaatgt tttacaatac caccataaat
     4501 attatctaca taaggtgggg aaaaattata agggagacca aaaacatcga ccttatcccc
     4561 ttttataaac tgatcagtaa tgcctaaaga tacaatagaa tcaacataaa gaatacattc
     4621 cgatcttttt tgtttagtat taatatgtat gctatttgta gtaacaaatg caatttctac
     4681 attttcataa tcgcatgggg taatattata ggcaaatctt aaacttcttt ttaaatcttt
     4741 taaattttca tctgcataag ctaattgact tccatagcta aaaacacatg ataatatgat
     4801 aattgtcaaa atgtttgttt tcatttaaaa ctttttatgt cctgttttat acctcttagc
     4861 ctaaataaaa atatcaatcg gtttcaacaa ctgatgacac tatagaagga ggaaattact
     4921 ttagtaaagt caacaaaaaa agagcacaca cccgaaaatc gcttagggct gctggattcc
     4981 tcccctgacc cacttcacgc acaagtgttg ctccgcctat tattatatca tattacggac
     5041 agtttgcaag ttttccaact aagtaaaatc actttcaagt gagcatagct tcattttggg
     5101 acaagatgga ctgaatacct agaaaaatca tgaccctttc caaacacgat tttgcttttt
     5161 gaaaatcttt ccctctcccc attccagcta ttctctatgt tataataaga ttattagatt
     5221 agaatgggag ttatgatgaa acaaaagatt aaaatcttaa cagtaattgg ccttatgaca
     5281 gttggtatgt ctgcgtgtca caacactagc aaaccttcta ataccgattc tgttttttct
     5341 ttaaccggaa aaaagcgcca acaaatcgtc aaacaagtaa gacaacggta ttatttccaa
     5401 caattatcca aaaccgaaca agaaaattac ctcactttat acgatagttt agcacaattt
     5461 cgtgaaatca tcagtttgac gccggcttct aaaaaaagct taattaaaac aattgacgcc
     5521 tttgtgatgg ataatcccga attttactgg attacatctg ccgattatcg atttgagttt
     5581 tctgatcaaa cggtctttgt cacctttcct atcccagaag atgccaagaa catttatcaa
     5641 gacttgcaag caatcggtaa tgatatcgtc gcaaacacgc catcaaagga tcgctatgag
     5701 caggtcaaat atttttatga ggtcatcatt cgagacacag actacaataa aaaagccttt
     5761 gaagcctatc aatcaggcag tcaagcccag gtcgcttcta atcaagacat taaaagtgtt
     5821 tttattgatc atttatctgt ttgtaatggc tatgcccaag cctttcagtt tctttgtcaa
     5881 aaagctggca ttccagtcgc ctatatccgt ggaactggta catctcagca acctcagcaa
     5941 tcttttgcac atgcatggaa tgctgttcaa attaataaca cttattatgg cgttgatgtc
     6001 acttggggtg accctgtttt tgataaccat ctctcacatc aaaagcaagg aactatcaat
     6061 tacagttttc tatgcctgcc agattatcta atggccttat cacatcagcc aagcaaagac
     6121 attgctttta atactaaaga acgttttgaa aatgtttgga ctataccttc ttgtacagat
     6181 gattctttgc tttattctaa acgtcatcaa agctatatct caacgtttga cagtgacgcc
     6241 atccttgcaa gccttgaaaa tcagttgtta aatagacaag agccactgtc tctacaattt
     6301 gctcatcaag atgattatca acaaatggta actgatttaa cgacgaatca aacaggttat
     6361 cataaccttt tcaatcagta ttggaataat tatacgggct ttacctatgg actcttacca
     6421 gagactctta gtatttcatt tgctagtagg aactaggttt agacacatga aacacaaagt
     6481 taagatgatt atctttgtca aacattacaa gaaattgata tactaacaca attgaaggcg
     6541 attattattc taaccgtctt caatagatat aaccttttca gattgagcac atctaatgct
     6601 tgtaacatta gcaacagtga tgagctcttt tttaatgctt tagcaaaata tatcagctaa
     6661 gacaaaagat taaataactc aagccatgcc tataagtcac ttgtttttaa tccctgtgtc
     6721 agtgtcaatc tacgcaacag ataactgaca gctctgagcc ctagaagtct gaacttgata
     6781 agtttactaa aaacaaaaat aaggtgagcc attactatct gtttttagat agtaaatctt
     6841 tttaagaatg actaactcat ctagtcatca cgtgttttat ttttcgattg ttttcatctc
     6901 gattgggtct gaaaaagagc gcttctagta cttggaaacg cccttttgta tattctatct
     6961 tcgtatgttg aatctaacaa ccattggaaa aatggtctaa cgtttcactc agtattttga
     7021 caggctaccc ttcaccaaaa atgcatgtga taacaaactc cttaaaactc tagtcaaagg
     7081 gatctgactg ttccttgatc aaatgcttag ctattttttt gcgctctcgc ccttggcgga
     7141 aaaaggtttg catgatgtta gcacagtctg ctgctagcag gcctcgttca acttgcacgc
     7201 gatggtttaa gcgctcatct gtcaaaatct ggtaaaggct gtctactcca ccaaattttt
     7261 gattgctggc tccataaata acatgcggaa tccttgctag cccaatggca ccactacaca
     7321 tcacacaagg ctcgatggtc acaaagagtg tggtatctaa taaacgccag ttgccttcat
     7381 gagcgttagc ctcgttaata gccatcattt cagcgtgcat aatggcttgg ttactctctt
     7441 cacgcgcatt gtgcccacga ccaataatct caccatcctt gacaatgaca cagccaatgg
     7501 ggatttcagc tttctgtaag gatttttcgg cttcttttaa agcctcttgc atgaaataag
     7561 tttgctcttc taaactatat ggcatcaaga aagactcccc aagttccaag atttgtgtgg
     7621 taaggcaagg tcaacaggaa tattacctgc ataggcctgt gtttcttgcc tcaacacttc
     7681 taaatggttt ttggaattaa taccatctgg aggaaccggt ggcatgtggg tcaagacaag
     7741 cttcttaaca cctgcctggc tagccattag tcctgcttcc ttactggtca aatgggccat
     7801 atgattttca ttgccttcgt ataagtaaac atccgctaag aaaaggtctg cttcttttgc
     7861 gaagtctgcc aatccttcaa aataaccact gtctccagta aagacaagta cctgaccagt
     7921 cgctctttct acaattcgaa aggcataaca cacaactgga tgaactgttt taagaaaggt
     7981 aatgtcaaaa gaaccaatct gttcaactcc agtaacatca taggctctac cttctgaaac
     8041 atcaggaatg cttaacttag caaattcgtt tcggtcctca tcatgcccat aaatgggcaa
     8101 tactttaggc tgccacaggt gtttaggata aagttgaaaa taatggcgca acacgcctaa
     8161 atcggccacg tggtctggat ggtaatggct aataatcact gcatccaaat cgagaggact
     8221 gatttctttt tccagctcat tgagcgctcg actaccagca tccatcaata actgaaagcc
     8281 gtcatgtcct gtgaccaaat aagaggttgt gcctgcatct tgatagggat aggctcccca
     8341 agaccctaag gtggttaatt tcatctcaaa cccttctttc ttgctttaac tcttattata
     8401 acaaaaatta gtgtcaaaga ggattgagac ccaccaaaaa caggtcctag cagataaatc
     8461 tgccaagacc tgttcaacac aacttaacta tttgatgatt agattactgt tttgtattca
     8521 aaaaactatc tttgtattta acagcgataa tggtcgcaat gattgctttg atggtatctc
     8581 ctggaataaa gaccaagttt gataaaagcg atgtcacaag agacatgcca gtgtaggctg
     8641 acaaccagat agcacccaga acatcaacca gtacaactcc tgagattaaa agagctagga
     8701 atgctaatgg cgtgcttttt gagaaccaat tgcggtaaag taatgaaaag acaataggca
     8761 caagaaggta ggcaataaca tagccagcag atggccccat caatactgga atggttgttc
     8821 ttgagcctga gaaaacaggt aagaaaaggc caatcactaa aaataagaaa acagataagg
     8881 ttcccttttt accacccagc atcaatccag ccaacatgac acctaagttt tgtaaaacaa
     8941 tagggactgg gataaagcct agcgggatag caggaataaa gcctaaaata ataatcaaag
     9001 tggtcatcat agccacctta acaagttctt tggttgtaaa catcagttac gactccttta
     9061 aaaaatagat atccttgtgc ctatgacagg ctggattaaa gggactttga caataaggac
     9121 agcatccaca accatactca gctcgactca agagctttcg acaatgccca caaataacag
     9181 gagatgtttc ttgatgtcct gttggcacaa aggcatgatc tgttaactgg tcatggcaat
     9241 ggtaacaagc ataataagtc tgacaagaag cacatttgag cccaacaata tcaagcgggg
     9301 tatgataatg taggcaccga tactcttggt caaggtcaat tccaaaacag tccgtcatat
     9361 ctcatcctct tgtaatagtt taatcaaaag cttatgattt gtcaactcta tttttacaaa
     9421 agggtaactg ttttctgaaa aagaacacgt aaaacaagaa cttcccttta aagagtgacc
     9481 tatcagttga aagcaatagg acatccgtct atacaaaaaa actgaaacca aagacgatag
     9541 atcgccctca gttccaggat catagcattt ttaattagaa attacggttt gatttattat
     9601 aaccataccg ttcaagaaaa tcttggcgga attcaagtaa gttatcgtcc ataatagcct
     9661 gacgtacttt tttcatcaag ttaaccaaga aataaaggtt gtggtagctt gtcaaacgaa
     9721 taccaaaagt ttcgtccgct tttagcaagt gacgaatgta ggcacggcta tagttttgac
     9781 aagtgtagca gtcacagtca tgatcaagtg gggtaaaatc ttcagcgaat ttggcatttt
     9841 taatcacaag acgcccctca ctagtcatac aagttccgtt acgggcgata cgcgttggca
     9901 agacacagtc aaacatatcg acaccacgaa tcacaccatc aatcaagcta tctggtgctc
     9961 ccactcccat caggtaacga ggtttatttt ctggtaagag gggagtcgta aagtcaagga
    10021 cggcattcat ttcttcatgg ctctccccaa cagctaaacc accaatagaa taacctggga
    10081 aatccatagc caccaaatct gccgcagact gacgacgaag gtcctcaaat ccagctcctt
    10141 gcacaattcc aaataatcct tggtcatgag gacgacgatg ggctttcaag ccacgttctg
    10201 cccaacggct agtacgttca atggattttt tcacgtaatc ataaggttgg taaaattgcg
    10261 ggcactcgtc aaaactcatc atgatgtctg agccaaggtt attctgaatg gaaatggctt
    10321 tttcgggtga tagaaacatt tttgagccat tcaagtgatt tttgaaagtc actccttctt
    10381 cagtgatgtt tcgtgaatcg gctaaagagt aaacttgaaa accacccgaa tcggttaaga
    10441 ttggctgatc ccagttcata aacttgtgca gaccaccaga gcgagcaatc aactcatctc
    10501 ctggacgcaa ccagaggtga taagtgtttg ataaaataat ccctgatcca attgctttta
    10561 actcttctgg agactgtgtt ttaacagtag cctgagttcc cactggcata aacattggtg
    10621 tcggaaaggt cccgtgaggg gtgataattt cgcccaagcg tgcaccggtg tgcttttctg
    10681 ctttgataag gcgatactta atcggataat ctgtcatgtg ctttcttcct tgctatcaag
    10741 ttaaacagtc ttgagctttt ttgatctgcc tgagtttcca tcataatgaa gggcttcaag
    10801 atgacatgtt gttctagcgc ctatcatttt atcaaaaaat ccataatttg tcatgctttc
    10861 ccaaaaaagt atagtcaaaa taatggttag ctgtctcatt ttgttttatg gtataatgaa
    10921 ataaaggagt ctgttatgtc aattaaagca atcaaaggcc aggctagaga cacgttaaaa
    10981 aatctctctg gcaagtattt actattttta attccaaccc ttctctttat gtttcatttc
    11041 ggtattgaga ttcatcaagg ttacgtccta tctagtggta ttgaagtctc gctagcggct
    11101 agttatttcc cattactact aggacttatc cttagccttt tcattttatc agcatccttt
    11161 acgatgattg atgttgttag gcattttcgt cagaaagttt cttttgccga atcaacaaca
    11221 gccttctcaa aagaattctt tgggaacctg ctggttttag cgatcactaa gtggctattc
    11281 tttctcatct ggtcactaat ttggtttttt ggcctcttta ttttcctttc cggactttca
    11341 gcgtttttgg tcaatgctaa atcaggtagc tcaacagtca tttcactgat ctttttacta
    11401 tttggagcag ttttgtcctt aattggtttt ggtatttata tcaaccgtta ttacgcttat
    11461 agtctatcag aataccttct ctacgatgag gttaaagagg ggacttatct aggagctata
    11521 gccgtcattg aaacaagtgt agctatgatg aaaggttata aatggaagct ttttttccta
    11581 caacttagct tcaccggttg gtttctactg aatattgtta cttttgggtt acttaatatc
    11641 tatcttttac catattttac aacagccaat gtcatttttt atgatcaact caagaaacgt
    11701 ttcaaagaca aagatgaccc aattgaagga gaacatttaa gccttcatca gcttaataaa
    11761 aatcctactc ctatgatgta tgacgatcaa aaagactaaa taaatcctcc atccataaaa
    11821 atagcccttg aactgcaccc caaaagttag acacaaaatc taacgattgg ggtgctattt
    11881 ttttatgaaa tttaatcaag aaacgaaagt taagatttat gagttacggc aaatgggaga
    11941 gtccattaaa tccatatcaa aaaagtttga tatggcagaa tccgatctca aatatatgat
    12001 tcgcttgatt gataggtatg gggtaaccat tgttcaaaaa tgtaagaatc attattattc
    12061 tccagaactg aagcaagaga taataaataa agtcctgatt gacggccaat ctcagaaaca
    12121 aacatcctta gattatgctt taccaacttc tagtatgctc tcaaggtgga tagcgcaata
    12181 caagaaaaac ggttatacta ttcttgaaaa accaagaggg agaccgagta agatggggcg
    12241 taaacgtaag aaaaatttgg aagagatgac agaggttgaa cgtcttcaga aggaattaga
    12301 ataccctaga gcggagaatg ctgtgctaaa aaagctgaga gaataccgct tgagggacga
    12361 agtaaagctc aaagagcaac agaaatcatt caagcattaa ggaatcaatt tcccttagag
    12421 atgctacttg aaatccttga tttatcacgc tccacctatt actatcaagt gaagcgacta
    12481 gctcaaggag ataaggatat agaactaaag catgtgattc gagagattta tgatgagcat
    12541 aaaggtaatt acggttatcg tcggattcat atggagttgc gtaaccgagg atttgtggtc
    12601 aatcataaga aagttcaacg tctcatgaaa gtcatgggct tagcagcccg cattcgtcgg
    12661 aagcgcaagt attcttctta caaaggagag gttggtaaga aggctgataa tctgattaaa
    12721 cgtcacttcg aaggctctaa accttacgaa aaatgttaca ctgatgtgac ggagttggcc
    12781 ttacctgaag gaaaactcta cttatcacct gttcttgatg gctataacag tgagattatt
    12841 gatttcactc tatctcggtc tcctaacttg aaacaggttc aaaccatgct tgagaagact
    12901 tttccagcag attcatacag cggaactatt cttcatagtg accaggggtg gcaataccaa
    12961 caccagtcct accatgattt tttagagtct aaaggtattc tggcatc
//
LOCUS       DAUGJR010000046        12878 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUGJR010000046 DAUGJR010000000
VERSION     DAUGJR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12878
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.046"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            166..693
                     /locus_tag="VH800_001500"
     CDS             166..693
                     /locus_tag="VH800_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEQ8362560.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            693..1811
                     /gene="yqeH"
                     /locus_tag="VH800_001501"
     CDS             693..1811
                     /gene="yqeH"
                     /locus_tag="VH800_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEQ8362561.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIGRINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLARFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPDKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            1836..2144
                     /gene="yhbY"
                     /locus_tag="VH800_001502"
     CDS             1836..2144
                     /gene="yhbY"
                     /locus_tag="VH800_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEQ8362562.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2213..2845
                     /locus_tag="VH800_001503"
     CDS             2213..2845
                     /locus_tag="VH800_001503"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEQ8362563.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLIDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            2842..3435
                     /gene="yqeK"
                     /locus_tag="VH800_001504"
     CDS             2842..3435
                     /gene="yqeK"
                     /locus_tag="VH800_001504"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEQ8362564.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3459..3812
                     /gene="rsfS"
                     /locus_tag="VH800_001505"
     CDS             3459..3812
                     /gene="rsfS"
                     /locus_tag="VH800_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEQ8362565.1"
                     /translation="MKKEELLKIVVEATEEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            3860..4603
                     /locus_tag="VH800_001506"
     CDS             3860..4603
                     /locus_tag="VH800_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8362566.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            4857..5963
                     /locus_tag="VH800_001507"
     CDS             4857..5963
                     /locus_tag="VH800_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEQ8362567.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENVID
                     YQKLIKVYEKKSEQMTAYLSTLEDTFSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6445..7161
                     /locus_tag="VH800_001508"
     CDS             6445..7161
                     /locus_tag="VH800_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8362568.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7364..8206
                     /locus_tag="VH800_001509"
     CDS             7364..8206
                     /locus_tag="VH800_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8362569.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8535..9380
                     /locus_tag="VH800_001510"
     CDS             8535..9380
                     /locus_tag="VH800_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8362570.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGTQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9630..10694
                     /locus_tag="VH800_001511"
     CDS             9630..10694
                     /locus_tag="VH800_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362571.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            10695..11387
                     /locus_tag="VH800_001512"
     CDS             10695..11387
                     /locus_tag="VH800_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362572.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11441..12811)
                     /gene="brnQ"
                     /locus_tag="VH800_001513"
     CDS             complement(11441..12811)
                     /gene="brnQ"
                     /locus_tag="VH800_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEQ8362573.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFVAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEMTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFIDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
BASE COUNT         4244 a         2033 c         2696 g         3905 t
ORIGIN      
        1 taagcagatg attgatttaa aaaggaatct tttcaaaatt gatgtccggg cacaaaagga
       61 tgaagagaaa gttttcatgc gtacggcgtg atttaactat ggttttaaat gctatttcaa
      121 aaaaaatatg ataaaataga aagtactaat tattttggag atgacatgag tatcgatgat
      181 tataggccga cctatatggt agaggctatt tatgatttaa gagcaaatga tttgttgcgt
      241 catggtatta cggctgtttt agtggattta gataatacct taattgcatg gaataatcct
      301 gatggcacac cagaggttcg cgcttggctt gatgaaatga ctatcgcgga tattagcgtg
      361 gttgttgttt caaataataa acattctcgt gttgagcgtg ccgtttcacg atttggtgtt
      421 gactttatta gccgtgcttt gaagccattt gcttatggta ttgaaaaagc cattgctcgt
      481 tatggatttg atcgcaacga ggttatcatg gttggagatc aactaatgac tgatatcaga
      541 gctagtcata gagctggaat aaaatcagtt ttagtcaaac cacttgttgc ttctgatgct
      601 tggaatacta aaattaaccg ctggcgtgaa cgccgtgtga tggcaaaatt agaagagaaa
      661 tatggtaaat tatcatatca aaaaggaatt taatggaaga attattttgt ataggctgtg
      721 gtatccagat tcaaactgaa gataaagaaa aagctggttt tacgccagct gctgctttga
      781 aaaagggtat ggaaacagga gaactctatt gtcagcgctg ctttagattg aggcattata
      841 atgaaattac agatgtccat attaccgatg atgaattttt aagacttctt cacgaagtgg
      901 gtgatagtga tgctcttgtg gttaatgtga ttgatatttt tgactttaat ggttctatta
      961 ttccaggtct atctcgcttt atttctggta atgatgtctt actggttggg aataaaaaag
     1021 atattttgcc aaagtctgtt aaggatggta aagttactca atggttgacg gaacgtgcac
     1081 acgaagaagg tcttcgccca ttagacgtta tgttaacgag cgctcaaaat aaatatgcga
     1141 ttaaagactt gattgggcgt atcaatgagt tacgtaatgg tcgagatgtt tatgttgtgg
     1201 gggtcactaa tgttggtaaa tcaaccttga ttaatgctat tatccaagag attactggta
     1261 acaaggatgt catcacgacg tctcgttttc ctgggacaac tcttgacaaa attgaaattc
     1321 ctttggatga tgggacgttc atttttgata cgccaggaat tattcacagg caccagatgg
     1381 ctcattattt atcccctaaa gagctaaaaa tagtgagtcc taagaaggaa atcaagccta
     1441 agacgtatca attaaatcca gaacaaactc tctttttagg tggtctggct cgctttgact
     1501 ttatcaacgg tgagcgtcaa ggatttacag ctttttttga caatcaacta gaattacatc
     1561 gtacaaaatt agctggagca gatgcttttt atgataagca tgttggaact ttgttaaccc
     1621 cgccagataa gaaagagttg actgcatttc ctaaattagt tcgtcatgaa tttacaattg
     1681 atcagaaaat ggatattgtt ttttctggtc taggatggat tcgtgttaat ggtcaaaaag
     1741 actcaaaagc gatagttgct gcatgggctc ctgaaggggt tgctgtcatt gttcgtaaag
     1801 cgattattta aaaataaaaa agaagttgga aaaaaatgct tacaagtaaa caaagagctt
     1861 tcttaaaatc tgaggctcat agcttaaaac cgattgtaca aattggcaaa aatggattaa
     1921 atgaccacat taagactagt attcgtcaag ctttggatgc tagagaattg ataaaggtca
     1981 ctttgttgca aaatactgat gaagatattc atgaagtagc agagatttta gaagaagaaa
     2041 ttgggtgtga tacggttttg aaaattggtc gtatcttgat tctctataag gtttctgcta
     2101 agaaagaaaa ccgcaagttg tcccctaaag ttaaagcaat ctagtccttt tatttgtata
     2161 gggactggtt ttatgagacg aggactattg tcgcgagaat tttggagaaa gtatggcatt
     2221 agaattgttg acgcctttta cgaaggtgga attagaggaa gaaaaaaaag aaagcaaccg
     2281 caaacagatt gggattttag gagggaattt taatcctatt cacaatgcac accttgtggt
     2341 tgcagatcaa gttcgccagc aattaggatt agatcaggtg ctattgatgc ctgaatgtaa
     2401 accaccgcat gtggatgcca aagagactat tgatgagaag catcgtcttc gcatgttgga
     2461 attggctatt gaagatgttg aagggctagc tattgaaacc tgtgaacttg aacgtcaggg
     2521 aatcagctat acctatgata cgatgcttta tttgactgag cagcatcctg atgttgattt
     2581 ttattttatc atcggagctg atatggttga ttatttgcca aagtggcacc gtattgatga
     2641 actggtcaaa ctcgttcaat ttgttggagt tcaacgtcca aaatataaag ctggaacctc
     2701 ttacccggtc atttgggtag atcttccttt gatagatatt tcttctagta tgattaggga
     2761 ttttattaaa aaaggtcgtc agcccaatta tctcttacct aagcgggttt tagactacat
     2821 tactcaagaa ggtttgtatc aatgacatat gaagattatc ttccttatag caggaccgaa
     2881 ctgttagcaa aaattgcaga gcagatgagc cctaaacggt ttaaacatgt acttggcgtg
     2941 gaaaaggcag ccttgtcctt ggcagagtgt tatggttgta acccagacaa agcagggtta
     3001 gcagctcttt tacatgatta tgccaaggag tgccctgacc aggtcttttt agacttaatt
     3061 gacaagtacc aattatctcc agaattagct aaatggaata ataatgtctg gcatggtatg
     3121 gttggtattt ataagattca agaagaccta gggctaaaag acaaagatat cttgcgagct
     3181 attgaaattc acaccgttgg tgctgctgag atgaccttgc tggataaggt cttatacgtt
     3241 gctgattata ttgaagaagg tcgcattttt cctttggttg atgacgctag aaaaatcgcg
     3301 aagctcgatt tgaatcaggc tgttgcctat gaaacagtga acactgtcgc ttatttagcc
     3361 tcaaaagcgc agcctatttt cccacaaact ctggatacct ataatgcgtt ttgcagctat
     3421 ttaaaggaat actaatggat aatgatatga ggaataaaat gaaaaaagaa gaactcttaa
     3481 aaattgttgt ggaagcaact gaggaaaagc gtgctaaaga tattttagcc ttggatttag
     3541 aggggttaac tagtttgacc gattattttg tgattgcgag tgcaacaaac agtcgtcaat
     3601 tagaggctat tgcggataat attcgtgaaa aggtaaaaga ggctggtgga gatgctagcc
     3661 atgttgaagg taatagccaa gcaggctggg tcttgcttga tttgaccgat gtggtggtac
     3721 atcttttttt agaagacgag cgttaccact ataatcttga aaaattgtgg catgaagcgc
     3781 ctgctgtggc tctagatgcc tatttagctt aatgttacaa agagaccttg tcaatacgac
     3841 agggtttttg aggatgataa tggaacataa ttatgaaaaa tttgcgtcag tttatgatgc
     3901 tgtgatggat gattctctat atgacttgtg gacagatttt tcacttcgac atttaccaaa
     3961 gtctaagggt cgaaatcgtt tgttagagtt ggcctgtgga accggtattc agtcagttcg
     4021 ttttgctcaa gcaggttttg atgtgactgg tttagactta agtcaagaca tgctggctat
     4081 tgctaaaaag cgtgcgcaat ctgctaaaaa gaaaattgat tttattcaag gtaacatgct
     4141 ggatttgtca caggtggggc agtttgattt tgtaacctgc tattcggatt ccatttgcta
     4201 tatgcaagac gaagttgatg ttggcgatgt ttttaaagaa gtttatgatg ttttagcaaa
     4261 cgatggcatc tttatttttg atgtgcattc aacctatcaa acggatgagt gtttccctgg
     4321 ttattcctat catgagaatg cagatgattt tgcaatggtt tgggatacct atgctgacga
     4381 ggctcctcac tctgttgttc acgaactcac tttctttatc caagaagacg atggacgttt
     4441 ttctcgcttt gatgaagtgc atgaggaacg aacgtatgag ttattgactt atgatatttt
     4501 gttggaacaa gcagggttca agtcatttaa ggtctatgct gattttgaag ataaggagcc
     4561 aactaagacc agcaagcgtt ggttttttgt agcatataaa tagaagaaaa aagtagcctt
     4621 tttagctata ggatttaatg aattatcttg aatgttactt atatgaaaag agttcattag
     4681 gcattaaatg ctattatcaa agcttagaag tattggagac attacgattg acactatgtc
     4741 tgaaggttgc taccaacttt aaagaaagca ttttctatta tacgttgtgc ttaagcattt
     4801 gatttaactc ttattagccc tataaaagac tatttagtac aatttgagga gattctatga
     4861 ctgttaccgg aattatagct gagtttaatc cgtttcacaa tggacacaaa tatttgctag
     4921 aaacagcaga gggactaaaa attattgcta tgtcaggaaa ttttatgcaa agaggagagc
     4981 ctgctcttat tgataaatgg attcgatcag agatggctct taaaaatggt gcagatattg
     5041 ttgtggaatt gccctttttc gtttcagttc aatcagcaga ctattttgct caaggagcta
     5101 ttgatattct ttgtcaatta ggaattcagc aattagcatt tgggacagag aatgtgattg
     5161 attatcaaaa actgattaag gtctatgaga aaaaatcaga gcaaatgact gcctatttat
     5221 cgacgcttga agatacattt agctatccac aaaaaacaca aaaaatgtgg gaaatctttg
     5281 ctggagttaa attttcaggg caaacgccaa atcatatttt ggggttaagt tacgcaaagg
     5341 ctagcgctgg aaagcatata caactatgtc ctatcaagcg tcaaggggct gcctaccatt
     5401 cgaaagacaa aaatcatctg ctagcttctg caagtgccat tagacagcac ctgaatgatt
     5461 gggatttcat aagtcattca gtaccaaatg caggtttact tataaacaat ccccatatgt
     5521 catgggacca ttatttttca ttcttaaaat atcaaattct gaaccattct gatttaacta
     5581 gtatttttca ggtcaatgat gaattggcaa gtcgtattaa aaaagcgata aaagttagtc
     5641 aaaatattga ccacctagtt gacactgttg ctaccaaacg ctatacaaaa gctcgtgtaa
     5701 gacgtatttt aacctacatt ttggttaatg ctaaggaacc tactttacct aaaggaattc
     5761 atattctagg gtttacctca aaaggacaag cacatttaaa aaaattaaaa aaaagcaggc
     5821 ctctgattac tagaattgga gcagaaactt gggatgagat gacacaaaaa gcagacagca
     5881 tctatcaact tgggcatcag gatatcccag aacaaagttt tggaagaata cctattataa
     5941 taaaaaatga gaggctcaat taaactctaa ttgagttttt ttgggggctt gactctaaca
     6001 ttacgttgat ggtttatact tcagttaatc caatgaggaa attttataac aataattaaa
     6061 aaagtcagtc aaaagatata ctttcgaaga acaggctaac gtttttacaa gattatatca
     6121 gtaatcattt tgacaattgt agtaatggaa tgttgccaaa atttagaacg ttgtatgtta
     6181 tggatgacaa gattttaaag gaatactaat taaacgggag gtcgtgaacc ggaagctgtt
     6241 gtcactcaag cgccaaaatc tgtctgtaac ataatattga tgtatgggaa cgcaattatt
     6301 tggtttttat tgtgatgctt aaaacgattt tatatttcta ttttaccaaa gcttttcaaa
     6361 gtgctataat aagggagtta gagtcaatat tagtaacgtt aatgttgaca atattcaata
     6421 aaatactatt aaaaggagac aaaaatggga cgtaaatggg caaatattgt tgctaaaaaa
     6481 actgctaaag atggagcaac atcaaaggtc tatgccaaat ttggtgttga aatttatgtg
     6541 gctgccaaac aaggcgagcc agatccagag ttaaatacag ctcttaaatt tgtcattgat
     6601 cgtgcaaagc aagcacaagt gccaaagcat gttattgata aagcgattga taaagctaaa
     6661 ggaaacacag atgaaacttt cgtagaggga cgctatgaag gttttggtcc aaatggttca
     6721 atgattattg tggatacttt gacatcaaat gttaaccgta cagcggcaaa tgtacgtacg
     6781 gcttacggta agaacggtgg caatatggga gcttcaggat ctgtatccta cttatttgat
     6841 aaaaaagggg tcatcgtttt tgctggtgat gatgctgaca gtgtctttga acaattactt
     6901 gaagcggatg tagacgtaga tgatgttgaa gcagaagagg gaacaataac agtttacact
     6961 gccccaacag atcttcataa aggtatccaa gcacttcgcg ataatggtgt agaagaattc
     7021 caagttactg aacttgaaat gattcctcaa tcagaagtag ttttggaagg tgatgacctt
     7081 gaaacttttg aaaagcttat tgatgcactt gaatcagatg atgatgttca aaaagtgtat
     7141 cataatgtag cagattttta aattgacata gaataataaa aagagttgaa atctatttca
     7201 gctcttttta agtgatgctt ttataagtaa gtaccaggta acatagtcgt tgttagaaga
     7261 taatgaacaa tagtaaatca gtatcaactt gataggaatc aattattagt gaactctaat
     7321 taaaaatggt aaactagaca caagaacaaa aaggagagat aggatgatta aaaaacagta
     7381 tttaggaagg gcaacaattg ccctagcatc gacccttgtg ctagcagctt gtgggtcatc
     7441 aaaaacagct gagtcaggaa atcaggggag ttctaaagaa gtcttatttg caacggttgg
     7501 aacaacagct cccttttctt atgaaaaagg tggtcaacta actggctacg atatcgaggt
     7561 ggctaaagca gtctttaaag gatcggatga ttacaaggtg tcctttaaaa aaacagaatg
     7621 gtcttctatc tttacaggtt tggactcagg aaaataccaa atgggtggta acaacatttc
     7681 ctttaccaaa gagcgttcag ctaagtacct tttttcttat ccaatcggat caacaccttc
     7741 tgttttagtt gttccaaaag acagtgatat caagagcttt gatgatatcc aagggcatac
     7801 gacacaagtt gttcaaggga ctacaagtgt tgcacagtta gaagacttta ataagaaaca
     7861 cagtgacaac ccggttactc taaaattcac caatgagaac attactcaaa tgttaaccaa
     7921 tttgagtgaa ggcaaggcag atttcaagat ttttgacgct ccaacggtta acgccattat
     7981 taaaaatcaa gggttagata atctcaaaac aattgaactc acctcaacag agcaaccatt
     8041 tatttatttt atctttagtc aagatcaaga gaaattgcaa agctttgtta acaagcgtat
     8101 taaagagttg actgctgatg gaactcttag caagcttgcc aaagagcacc ttggcggtga
     8161 ttacgtgcca tcagataaag agttgaaact tcctacagct aactaaacca tctattaacc
     8221 agttattcat ctagaagact ggtttttctg atcggaaaca atattatagt ttatgaggtt
     8281 atgttataaa aattgcaaat agccttaatc aaaatgagat gttaaagtgc tttttgagaa
     8341 gtgaatattg tataagaagt atgctttggg ttttagtcct caaataccaa gttttttgtt
     8401 gactaaacaa ataaggatgg ttagcatagc atatagttta aaactatggt atatgctagc
     8461 cattatcaat ttgaaaacta tatctaatta agatacaata atgatcgtaa acaaaatgaa
     8521 tcgaggataa cgctatgtct tttaaaaaat ggattggaat agtcggaatc gctttagcat
     8581 caactgtatt ggttgcttgt tctgaaaaac aagatgataa aaacacttta actattgggg
     8641 tgatgacaaa aacagaatct gatcaagcga gatgggataa agttgaagaa ttattgaaaa
     8701 aagacaatat cactttgaag tacaaagaat ttacagatta ctcgcaacct aataaggcag
     8761 ttgctaatgg tgaagtcgat attaatgcct tccaacacta taatttctta aataactgga
     8821 ataaggaaaa taaggaacat ttggtggcca ttgctgatac ctatatcagc ccaattaacc
     8881 ttttctctgg aaccagtcaa gatggaaagg ctaaatacaa atcagtagct gatctgccaa
     8941 atggtactca aattgcagta ccaaatgatg cgaccaatga aagccgtgcc ctctatgtgc
     9001 tgcaatcagc tggcctcatt aaattgaatg tgtctggtga tcaattagca accattgcca
     9061 atatctcaga gaacaaaaag aaattagata tcaaggaatt agatgctagc caaacggcac
     9121 gtgctttagt atctgctgat gcagctgttg tcaataatag ttacgctgtt cctgcaaaaa
     9181 ttgactacaa aacctctctt ttcaaagaaa aagcagatga caattcaaaa cagtggatta
     9241 acattattgc aggtcaaaaa gattgggaaa aatcagagaa ggctgatgct attaaaaaac
     9301 tcatcaaggc ctaccaaact gatgaggtga agaaagtcgt ggaaaaaact tcaaatggta
     9361 tagatgtatc cgtatggtaa attttagcca ttgttataac aagagtgtgg tcgtgtttaa
     9421 aacacatgct ttcttgcatg cttgaggaag agtttacgac taatttacct ttagaaagct
     9481 atttaagacc ttttcccttt taggatttag aaaccttggg aagactattg catgttatct
     9541 taatagtcat gattatgcag gcgatgaaaa cattgctatc gtagattact gtcgccatat
     9601 cgtactaata gaggagttat taaaatctta tgaatgaagc aataattcaa ttagatcata
     9661 ttgatattac cttccgtcaa aaaaaacggg ttatcgaagc tgttaaagat gtcacggttc
     9721 atatcaatca aggagatatt tatggcattg ttgggtattc aggtgccggg aaatcaactc
     9781 ttgtgcgtgt gattaacctg ctacaggcac caacaaacgg gaaaatcact gttgatgggg
     9841 atgtgacttt tgaccagggg aaaattcaat tgtcagctga tgcccttcgc caaaaacgac
     9901 gtgatattgg tatgatcttc caacatttca atttgatggc ccaaaaaaca gccaaagaaa
     9961 atgtagcatt tgcgctccgt cattcgtcgt taagtaagac tgagaaagaa cacaaagtta
    10021 tcgaactgct agaacttgta ggtttatcag agcgagcaga taactaccct gcccagttat
    10081 cgggtgggca aaaacaaagg gtggctattg cgcgtgctct agctaacgat ccaaaaattt
    10141 tgatttcaga tgaggccaca tcagcactag atccaaaaac cactaaacaa attttggcgc
    10201 tcttgcaaga attaaaccgc aaacttggcc ttaccattgt tatgattact catgaaatgc
    10261 aaattgttaa ggatatttgt aatcgtgttg ctgttatgca aaatggtgtt ttgattgaag
    10321 aaggttctgt ccttgatatc ttttcaaatc caaaagaagc cttgacacag gaatttatca
    10381 caacagctac agggattgat gaggctttag aaaaaattaa ccaacaagac attgttaaac
    10441 atttgcctgc aaatgccctt ctagctcagt tgaaatatgc aggaacttct acggatgagc
    10501 ctctacttaa tagcatttac cgtcagtttg aagtgacagc taatattttg tatggcaata
    10561 ttgagatttt agatcatatt ccagttggtg acatgattgt tgtcttggaa gggcaagctg
    10621 aaaatattct tgcggctgag aaagccttgc atgaagctgg tgttgatgtt agtattttaa
    10681 agagaggagc ctagatgtca cagttaattc aaacttattt gccaaatgtt tatgaactcg
    10741 gatggtctgg agatgctggt tggggcttag cgatttggaa tactttatac atgaccattg
    10801 tgccttttat tgttgggggt gctattggtc tcttattagg cttgttatta gttttaacag
    10861 gaccggacgg tgttattgaa aacaaaacga tttgttgggt tattgataaa gttacctcta
    10921 tttttagagc cattcctttt gttattttga ttgctatttt agctagcttt acctatttgc
    10981 ttttaagaac aactttagga gcaacagcgg ccttggtacc tttaaccttt gcgacttttc
    11041 ctttttatgc ccgtcaggtc caagttgttt tttcagaatt agacaagggt gttattgaag
    11101 cagcacaagc ttcaggtgct actttctggg atattgtcaa agtgtatctc agtgaaggtt
    11161 taccagatct tattcgtgtt tctacagtca ccttaatttc tttagttggg gaaactgcca
    11221 tggcaggagc tatcggtgct ggaggattag gaaatgtagc gatttcttat ggttataatc
    11281 gttttaacaa tgatgtgact tgggtagcga ctattattat tcttttaatt atttttgcta
    11341 tccaatttat tggtgatagc ttgactagaa ggtttagtca taaataaacg aaacaacacc
    11401 ctaagtaaaa acttagggtg ttgttgttta gatgatgtca ttagcttttc ttcgttttac
    11461 ttagtataag ccctattaaa aaaccaatag cagcaaagat aatccatccc attgagaatt
    11521 gccctagtgg aacagttttt tggaaaaaag ttacaacggc ttctggtaaa tgaaataatc
    11581 cagtcatttg tgatagtgtt aggagtgcat caaatatggc aggaataaag gttagaccaa
    11641 ttgtagttcg atagacaata ggatcattat tgaagcattt ttgtgccaaa acaaggaaaa
    11701 ttaaatcgac tgttaatggg tataaaagga ataaaacagg agctgaccag ttgataatga
    11761 ctgataagcc accaaaataa aagaaagctg atagtaaagt aaagatagtt gcccaagcaa
    11821 tatgagataa agcaggcact aatttatgga agtattcagc acttgacgtg attaagcctg
    11881 ttgaagtggt tagacaggcc aggaaaatca caacagctag aaatgcttgt ccgatgccac
    11941 ctaggtaaaa acgagaagca tgacttaaga tttgaccgcc attaactgga ttaccatgaa
    12001 gggtaaagct gccatcaata aaaggaaata atgattgtga tgttgctcca atacgaccga
    12061 caaagatata gacaagtgct aatagcaaaa tggcaatagc cccagaaata agtgttattt
    12121 tggtcatttc tttgtccgtc ttagcgccaa attgtttggt agcctcaatg actaaaatag
    12181 caaaaacaag agaagctagt gcatccatag tgccataacc ttgaattaat cctgctacaa
    12241 aaggaaaatc tttaaaggca ttattaacac cgaccccagc gttaaaagca tcaccgtaat
    12301 ttccagcagg atggacaaag gacgcgataa ccaaaataga aataacaact aacaacgttg
    12361 gcgttaaaaa ttttccgata ttttcagcta gtttactagg tttgatagca aggaagtagg
    12421 acagaccaaa aaatagtata gcataaatag ctttattggt tgtattatct cctaagatag
    12481 gagcgatacc gactgaaaaa gaagtggctc ctgttcttgg aatagcaaaa aatgggccaa
    12541 tagataaata caaaatggaa gaatagaaga ttgcatacca tttagagatg gggcgtgcca
    12601 aactttcaac atcgcctgat ccagatttag caacagcaat gacaccgagt aaaggcaagg
    12661 agacaccagt taaacaaaaa ccaatgatag accatagaat ctgatgacct gagtagatgc
    12721 ctaaaaaagc tgggtaaatg aggtttgctg ctccaaaaaa tagcgcaaat agcatgaatc
    12781 caatgacgat atatacattt ttttgtttca tttataaata gtctttctat tgatactaat
    12841 ccgaagattc taacaatttt aattatatta tgtgtcaa
//
LOCUS       DAUGJR010000047        11669 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUGJR010000047 DAUGJR010000000
VERSION     DAUGJR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11669
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.047"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            5..78
                     /locus_tag="VH800_001514"
     tRNA            5..78
                     /locus_tag="VH800_001514"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            158..231
                     /locus_tag="VH800_001515"
     tRNA            158..231
                     /locus_tag="VH800_001515"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:192..194,aa:Arg,seq:acg)
     gene            257..808
                     /locus_tag="VH800_001516"
     CDS             257..808
                     /locus_tag="VH800_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ8362574.1"
                     /translation="MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRH
                     YYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQ
                     KRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
                     RFKGRRALLRKISPYFKEFAQQL"
     gene            993..1742
                     /gene="truA"
                     /locus_tag="VH800_001517"
     CDS             993..1742
                     /gene="truA"
                     /locus_tag="VH800_001517"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEQ8362575.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            1732..2496
                     /locus_tag="VH800_001518"
     CDS             1732..2496
                     /locus_tag="VH800_001518"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEQ8362576.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            2486..2956
                     /locus_tag="VH800_001519"
     CDS             2486..2956
                     /locus_tag="VH800_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8362577.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            2970..3530
                     /locus_tag="VH800_001520"
     CDS             2970..3530
                     /locus_tag="VH800_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEQ8362578.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(3595..4440)
                     /locus_tag="VH800_001521"
     CDS             complement(3595..4440)
                     /locus_tag="VH800_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEQ8362579.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            4761..6044
                     /locus_tag="VH800_001522"
     CDS             4761..6044
                     /locus_tag="VH800_001522"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEQ8362580.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            6261..6836
                     /locus_tag="VH800_001523"
     CDS             6261..6836
                     /locus_tag="VH800_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEQ8362581.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            7093..8697
                     /locus_tag="VH800_001524"
     CDS             7093..8697
                     /locus_tag="VH800_001524"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEQ8362582.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            8865..9791
                     /locus_tag="VH800_001525"
     CDS             8865..9791
                     /locus_tag="VH800_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8362583.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYASVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            9845..9930
                     /locus_tag="VH800_001526"
     tRNA            9845..9930
                     /locus_tag="VH800_001526"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9879..9881,aa:Leu,seq:aag)
     gene            10137..11018
                     /locus_tag="VH800_001527"
     CDS             10137..11018
                     /locus_tag="VH800_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEQ8362584.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            11400..11588
                     /locus_tag="VH800_001528"
     CDS             11400..11588
                     /locus_tag="VH800_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEQ8362585.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
BASE COUNT         3812 a         1816 c         2530 g         3511 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gagagaggta ggaagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggtaagatag aggcaagata tgcgttggca cccttagctc aactggatag
      181 agtacctgac tacgaatcag gcggttagag gttcgactcc tctagggtgc ataatgaaaa
      241 aaacaacagg acattaatgt cctgttgttt ttttgtggtt ctctttatac tagggatagt
      301 taaaaagaaa aggagactca aaatgtcgat agagacaaga gcagcgtttg aaaaagttaa
      361 gcccattatt ttgaaattaa agcgacacta ttatattcaa ttgtgggata gagatgactg
      421 gttacaagaa ggacatatta tcttattaca gttactagaa aggtacccag agttaattga
      481 ggaagaagag cgtttatatc gctattttaa aacaaaattt tcatcttatt tgaaagattt
      541 attacgccgt caagaaagtc aaaagcgtca gttccataag ttagcatatg aagagatagg
      601 ggaggttgca catgccattc catcgagagg gttatggcta gacgactatg tggcttatca
      661 agaggtaata gctagcttag agaaccaatt aaattcgcaa gagcgtatgc agtttcaagc
      721 acttatcagg ggcgaacgtt tcaagggaag acgtgctcta cttaggaaga tcagtcccta
      781 ttttaaggaa tttgcacagc agttgtaagc aagacctata aggaattggg ggtaaatcta
      841 tgaaaaaagg agagagtttg gaggaaatag ctttcttata gcttttaaat cgctagtagc
      901 ttagagtaag cttcaatacg tctttcattt gtttgggtac agtttgatta aaaatagttt
      961 ctcttacgtt taagaaatgt taaaatagta acatggtaag atacaaagca acgatttcct
     1021 atgatgggac tcttttttcg ggttttcaaa gacaaagaca tttacgtacg gttcaagaag
     1081 agattgaaaa aacactctat aaattaaata acggtacaaa aattataatt catggtgcag
     1141 gacgtacgga tgcaggagta catgcttatg gacaggtgat ccattttgat ttgcctcaag
     1201 aacaagaagt tgaaaaattg cgatttgctc ttgatacaca gactcctgaa gatattgatg
     1261 ttgttaatat agaaaaagtg gctgatgatt ttcattgtcg ttatcagaag catttaaaaa
     1321 cttatgaatt tttagttgat aatggtcgac ctaaaaatcc gatgatgcga cactatacca
     1381 ctcattaccc ttatactctt aatattaaac ttatgcaaga agctattaac ggtctggtag
     1441 gtacacacga ttttactggt tttacagcag caggaacttc ggtacaaaat aaggtgcgaa
     1501 cgattaccaa agcaacggta tctcgggatg aaaaaactga ttttttggtg tttacttttt
     1561 caggaaatgg ttttctctat aagcaggtga ggaatatggt gggaactttg ctgaaaattg
     1621 gtaatggtca aatgccagtt gaacaagtta aagtgatttt gagctccaaa aatcgtcagc
     1681 tagctggacc aacgatatct ggaaatgggc tttacttgaa ggagatttgt tatgaaaact
     1741 gattatatcg tgactatatc tgggaacgat attttaagtg gaggtggtct ctatgctgat
     1801 ttagcgactt acataaggta tgacctacag gcctttgtag cggtaacttg tttaactact
     1861 agatctgaag agggctttag tctatttccg gtagctaaag aaattttccg tgatcagttg
     1921 aatagcttta cgaacgctcc aatttctgct attaaaattg gtttgttacc taatgcggaa
     1981 atgtgtgaaa tagttttgga ttttataaag gggcatctgg gaatcccagt ggttttagat
     2041 cctgttctag catgtaaaga aatagatgat gttaaaatag ttcctctaag acaggagatt
     2101 ttacaattat tgccttatgt gactgttgtt actccaaatt tggtagaggc tcagctatta
     2161 tctcaaaaag agattgtttc tttaaaagat atgcaagaag ctgctaaata tttttatcaa
     2221 cttggggcaa aacaggtggt tatcaagggt ggtaatcgat ttagtcagaa aaaagctatt
     2281 gatctttttt atgatggtaa agagattgtt accttggaat gtcctgtact tgagaaaaat
     2341 aatattggcg caggctgtac ttttgcatct agtatcgcta gtcagttagt aaagaaaaaa
     2401 acgccactag aagctgtgaa aaactcaaaa gagttagtct accaagctat tttacaatct
     2461 gatagatacg gagtaaaaca aagttatgca aaatagtaag atacgacaaa tgagtttaac
     2521 agggatattg acagcattgg ttgttgtttt aggaagattt gtcatgctac ctactccaac
     2581 aggtttttta acgctgttgg atgcaggaat ttatgctgtc agcttttcct ttggatcagc
     2641 tcaaggagct attgtgggag ggttatcagg ttttttaatc gatttagtgg caggataccc
     2701 tcagtggatg tttcatagtt tgattgctca cagtgtccaa gggtattttg cgggatggag
     2761 agggcgcaag cgttggcttg gtgttgtgat aggttctttt atcatgattt tttggtactt
     2821 tttaggctct cttatgcttg gttatggcct ttcgggatct ttagccggta tttggggaaa
     2881 cgtcatgcaa aatacattag ggctttttgt tggttttatt atctttaagg ccatattaag
     2941 gcaaaaaaag agataaggag agtgagaagt tgttgaataa tttagagaaa caaacaaggg
     3001 aaatcgtcat tgatgttgta gaacgctctg ctattcaacc aggtaatctt tttgttctag
     3061 gtctttcatc tagcgaaatt ttgggtagta gaattggaaa acaatctagt ctagaagtag
     3121 gtcaaatagt tgttgaagtt gtgttagatg aattaaataa gcgtggtgtt catttggctg
     3181 tacaaggttg tgaacacgtc aatcgtgcct tggtagtaga gaggcatgtg gcagaatcta
     3241 agcagttaga gattgtcaat gtggttccga atcttcatgc tggtggcagt gctcagatgg
     3301 ctgcttttca acttatgtca gaccctgtcg aagtagaaga agttattgca cacgctggac
     3361 ttgatatagg tgatactgct ataggaatgc atattaagcg tgttcagatc cctctgattc
     3421 cttgtcaacg agagctagga ggtgctcatg tgacagcttt ggctagtcga ccaaaattaa
     3481 ttggtggagc tagggctgat tacaatatgg atattatccg taaatcctaa accctttttt
     3541 ctggaataaa acaattggtg ttttttctag aaaaaaggat tttttaagat tatattaaga
     3601 ttttgaggtg atagaatagc tgattgcagt cggtaattga atgccttctt tgagtaaagc
     3661 ttcttgataa agtctataaa aagtatggta aatcttaaat tgttctccat tttctgtgaa
     3721 aatagcaatt ctaaaagtga actgtccatt agagttattt tgaggcccta aaatatttgg
     3781 tttgccaacg atttgaggat ggtttggcaa ttccttttga ttcacttcat caatgattcg
     3841 agtgacttgg ctcaaattaa cagtggaata aagaggaatt tcaattaagg cacgcatatt
     3901 accacgagat ttgttgctga caacggtgat gctacggttt gggatgaaat gtagtgttcc
     3961 atcgaatcca cgaatttgag tagttctaat tccaacacca aagacactgc cttctatgtc
     4021 agagatagta acgttatctc ctacttcaaa ttgattctca aataagataa aaaagccatt
     4081 gacaacgtca gataaaaatc cttgtgcacc taacccgatt gctactccag caattccagc
     4141 tcctgctaga agactagaga caggtatgcc aaataagcta agtatccaat aaatgagaag
     4201 aaaatataat aagtaattta aaatgttgtg agtgagctta gagagtgttt ttttgcgagc
     4261 ttcactttgt cttgaataag caaacgattt gttaatggtt ttttcaaaaa gatagttagt
     4321 aacacgtttt aaaatagcaa aaaagagtaa tagaataatg agagacacta gctttttaaa
     4381 aatcgttaag ccaatatttt cgatatgaga ctgctctagg taatgtaata taaatgtcat
     4441 gagaaatcct ttctttgata gtttatcaaa aaaaaaccaa tcttgaaaag agataaatta
     4501 atattttaac caaagttatg ataattgttt tatcataaag aatgccatag tcatccgttg
     4561 tgataatgct tgaaaatagt cagttagtaa gcgaaaaagt ctaacattaa cctttataaa
     4621 ttgaaaataa ctgttagtag actaatgaca ggtagatact cttaatagcg cgtttgattt
     4681 cacgcataaa aagctttaaa aacgctttaa attatgataa aatgaactgt atcgaaatta
     4741 ttttaaggag aaatgactta atgtctacat catttgaaaa caaagctaca aatcgtggcg
     4801 tgattacatt tacaatcagt caagataaaa taaaaccagc tcttgataaa gcttttaata
     4861 aaatcaaaaa agacttgaat gcaccaggtt tccgtaaagg acacatgcct cgtccagtct
     4921 tcaatcaaaa atttggtgaa gaagttcttt atgaagatgc tttgaatatt gtattgccag
     4981 aagcttatga agcagctgtg acggaacttg gtcttgatgt ggttgcacaa ccaaaaatcg
     5041 atgttgtgtc aatggaaaaa gggaaagagt ggacactttc tgctgaagtt gtgacaaaac
     5101 ctgaagtgaa acttggtgat tacaaaaacc tagttgtaga agttgatgct tcaaaagaag
     5161 tttcagatga agacgtggat gctaaaattg agcgcgaacg tcaaaacctt gcggaactca
     5221 ttattaaaga cggtgaagca gctcaaggtg acactgttgt gattgacttt gttggttcag
     5281 ttgatggtgt tgagtttgat ggcggtaaag gagataactt ctctcttgaa cttggttcag
     5341 gacaatttat cccaggtttt gaagatcaac tagttggtgc taaagctggc gatgaagtag
     5401 aagttaatgt cacattccca gaatcttacc aagcagaaga tcttgcaggt aaagccgcta
     5461 aatttatgac aactattcac gaagtcaaaa caaaagaagt accagagctt gatgatgagc
     5521 ttgcaaaaga tattgatgaa gatgttgaca cacttgaaga cttaaaagta aaatatcgta
     5581 aagaacttga agcagctcaa gaaactgctt atgatgatgc tgttgaagga gctgcgattg
     5641 aattagcagt tgcaaatgct gaaattgttg atttacccga agaaatgatt catgaagaag
     5701 tcaaccgttc agtgaatgaa tttatgggca acatgcaacg tcaaggaatc tcacctgaaa
     5761 tgtacttcca attgactggt acaactcaag aagatttaca taaccaatat tcagctgaag
     5821 ctgacaaacg tgttaaaaca aaccttgtta ttgaagcaat tgctaaagca gaaggttttg
     5881 aagcaacaga tagtgaaatt gaacaagaaa ttaatgacct tgcaacagaa tataacatgc
     5941 cagctgacca agttcgttct cttctttcag cagatatgtt gaaacatgat attgcaatga
     6001 aaaaagcagt tgaagtgatt acaagcacag caagcgttaa gtaatcttat taaggaacaa
     6061 aacgtacaag ccggattaga acgtctttct agtctggttt ttctttttct aaagaaataa
     6121 taaggaatta gttaaacgtt attttaatga attagcttta aagatttgtc aagaagaagt
     6181 gatatgagtt gataaaagtt ttgacgaatt acttttttta gcgtaaaatg gtagagaatg
     6241 ataaaataag gagaactgcc ttgaaattag acgtatttgc aggacaagaa aaaagcgagc
     6301 tttccatgat tgaagtggcg cgtgccattt tggaagaacg cggtcgcgac aatgagatgt
     6361 actttagcga tttagtcaat gagattcaaa attacttagg aaaatctgat gcaggtattc
     6421 gtcatgcatt accatttttc tatactgact taaatacgga tggctcattt attcctctag
     6481 gtgaaaacaa atggggactt cgttcgtggt atgctattga tgaaattgat gaagaaatta
     6541 ttactctaga agaagatgaa gatggcgcac aaaaacgtaa gaaaaaacgc gttaatgctt
     6601 tcatggatgg agatgaagac gctattgatt atagagatga tgatccagaa gatgaagatt
     6661 tcacagaaga atcagctgag gttgaatatg atgaagaaga tccagatgat gaaaaatcag
     6721 aagtggagtc atatgattca gaattgaatg aaattatccc tgaagatgat tttgaagaag
     6781 ttgatatcaa tgaagaagac gaagaagatg aagaagatga agagccagtt ctctaatgtc
     6841 tttagttcag aaataaaaat gtaattatca tttgacaaat tgtctattat agtttatatt
     6901 attattcggg cacctcttta tgaggtcagg caaaagctct ctagttaata gggggctatt
     6961 tttgttttct agaataatgc cagtttgcct ctatatttag aaaactaagg tgatacctaa
     7021 ccaatgtgga accaactaat agggaattaa caagaaagca atgcttttat tcagcttata
     7081 taaaggagta ctatgacgaa atacattttt gtaactggtg gtgttgtatc atcaattggc
     7141 aaaggaattg ttgcggcaag tcttggccga ttgttaaaaa atcgtggact taaggtgacg
     7201 attcaaaaat ttgatcctta tattaatatt gatccaggga cgatgagccc ctatcagcat
     7261 ggagaagtat atgtgacaga tgacggtgct gaaaccgact tggatttggg tcactatgaa
     7321 cgttttattg atatcaatct taataaatat tccaatgtta caacaggtaa aatttatagt
     7381 gaagtccttc gtaaagaacg taaaggcgag taccttggag cgactgttca ggtgattcct
     7441 catatcacag atgcccttaa agaaaaaatc aaacgcgcag cttcaacaac ggactctgat
     7501 gtaattatta ctgaggtcgg ggggactgtt ggcgatattg aaagtttacc gttcttagaa
     7561 gctcttcgtc agatgaaagc tgatgttggt tctgaaaatg tgatgtatat tcacaccacc
     7621 ttgttgccat atttaaaggc agcgggtgaa atgaaaacta agccaacgca acattccgtt
     7681 aaagaattgc gtggtttagg gattcaaccg aatatgttgg ttattcgtac ggaagagcca
     7741 gttgagcagg ggattaaaaa taaattggct cagttctgtg atgtgaattc agaagctgtt
     7801 atcgagtcac gtgatgtaga acacttgtat caaattccat tgaacttgca agctcaatca
     7861 atggatcaga ttgtttgtga tcatttgaaa ttgaatgcgc cacaagctga tatgaccgag
     7921 tggtcagcta tggttgacaa ggtgatgaat ttaagaaaaa caacaaaaat tgccttggtt
     7981 ggtaaatatg tggaattgcc agatgcctac ttatctgttg tggaagcctt gaaacattct
     8041 ggttatgcca atgataccgc aattgaccta aaatgggtca atgctaacga tgtgacggtg
     8101 gataatgcag ctgacttgtt gggagatgcg gatgggatta ttgtaccagg tggttttggt
     8161 caacgtggta cagaaggcaa gatccaagcg attcgctatg cccgcgaaaa tgatgtgcca
     8221 atgcttggta tttgtcttgg catgcagttg acttgtgttg aatttgcccg ccatgtcctc
     8281 aatatggaag gtgcaaactc ttttgaatta gagccaagta ctaaataccc catcattgat
     8341 atcatgcgtg atcaaattga tattgaagat atgggaggta cgcttcgtct gggattgtac
     8401 ccatgtaaat tgaaaccagg ttcaaaagca gcaatggctt acaataatca agaggtggtg
     8461 caacgtcgtc atcgtcaccg ttatgagttc aacaacaaat tccgtccaga atttgaagca
     8521 gctggttttg ttttctcagg ggtatcacct gacaaccgct tagttgaaat tgtagaattg
     8581 aaagagaaaa aattctttgt agcagctcaa taccacccag aattgcaaag ccgtccaaat
     8641 cgtcctgagg agctatacac cgcttttgtt acagctgcta ttaaaaatag caattagtgg
     8701 ttttaagggt aagtttgtgg cattctactt ggctggcaga tactgataaa gattactagc
     8761 tattaaaggg atcttttcta taaaaatagc attagaaaaa gaaaaacgtg atatttttag
     8821 gttagcactt tctttttcag tcattttttt gtaaaatact tggtatgaaa actattcgaa
     8881 tagcaaagta tttaggaatt ctattccttt tgataactct tattagcgta ggtgctagtt
     8941 tttatttctt tcatgttgca caaataagag aagagaaatc gtttattaat aataagaaac
     9001 ggagtacaaa taatccatta tacccagctg aacagtcttt tgacgcttta ccttacgaaa
     9061 aacgtcaact aacaaatcgt gggttaaaac aagtggggtg gtacttacca gctgctcaaa
     9121 aaacaaaaaa gacagctatt gttgttcatg gttttacgaa tgacaaagaa gatatgaagc
     9181 catatgccat gctttttcat gatttgggct ataatgtctt aatgccagac aatgaggccc
     9241 atggggaaag tgaagggaac ttgattggtt atggctggaa tgaccgcctt aatgtcatgg
     9301 cttggacaga ccaactgatt aaggaaaacc ctgaaagcca aatcacactc tttggcttat
     9361 ctatgggtgc tgcaacagta atgatggcaa gtggtgagcg attgcctgcg caagtcacct
     9421 ccctcatcga agattgcggt tatgccagtg tttgggacga attgaagttt caggccaagg
     9481 ctatgtacaa cttgcctgcc tttcctttac tctatgaagt ctctgcctta tctaagattc
     9541 gagcaggttt tagttacgga gaagcgagct cagtgaaaca gctggctaaa aataaacgtc
     9601 caactttatt tatccacggt gataaggatg attttgttcc tacaaaaatg gtttatgaca
     9661 attataaggc cacgaaaggt cctaaggaaa tcttgattgt taaaggggca aaacacgcca
     9721 aatcctttga aacaaaccca gaacaatacc agaaaaaaat tgccgctttt ttgaaaaaag
     9781 ttgagaaata agtattgaca gttaaactca cagttgctat aataatttat gttactgatg
     9841 agtagcgggg atggcggaat tggcagacgc gcaggactaa ggatcctgtg accgctttag
     9901 gtcgtgtggg ttcaagtccc actctccgca taatgtaaga ggtgaatcat tgattcgtct
     9961 cttttttttg gttaaatgaa ggataagaag gcatagattt actggagaaa acttttgata
    10021 atctgctttt ggaaaacgct ttaagcttgt gaaaggctag aaatttatgg aaaattgtgc
    10081 tagaatgaac aatgtaaacg gggagttatc ccgaaaaata agaggaggcc ttacaaatgg
    10141 caatcgtttc agcagaaaaa tttgtccaag cagctcgtga aaacggatat gctgttggtg
    10201 gatttaacac aaacaactta gagtggactc aagcaatctt gcgtgcagca gaagctaaac
    10261 aagctccagt tcttatccaa acatcaatgg gtgcagcaaa atacatgggt ggttataaag
    10321 tatgtcaatc tcttattact aaccttgttg agtcaatggg tatcactgtt cctgttgcta
    10381 tccaccttga tcatggtcac tacgaagatg ctcttgagtg tatcgaagta ggttacactt
    10441 caatcatgtt tgacggttca caccttccag ttgaagaaaa ccttgctaaa actgcagaag
    10501 ttgttaaaat tgcacatgct aaaggcgttt cagttgaagc tgaagttggt acaatcggtg
    10561 gtgaagaaga cggtatcatc ggtaaaggtg agctcgctcc aatcgaagat gctaaagcaa
    10621 tggttgaaac tggaattgac ttcttggcag ctggtatcgg taacatccac ggtccatacc
    10681 cagaaaactg ggaaggtctt gctcttgacc acttagaaaa attaacagca gctgtaccag
    10741 gtttcccaat cgtattgcac ggtggttctg gtattcctga cgatcaaatc aaagaagcaa
    10801 tccgtcttgg tgttgctaaa gttaatgtta acactgaaag tcaaatcgct ttctctaacg
    10861 caactcgtga atttgctcgt aactacgaag ctaacgaagc agaatatgat ggtaaaaaat
    10921 tatttgaccc acgtaaattc ttggctccag gtatgaaagc tgttcaaggt gctgttgaag
    10981 aacgtatcga tgttttcgga tcagctaaca aagcataatt tagagtatta aacaccctaa
    11041 agccctcttg agggcttttt tagatataat tgacacccta aaatggatac cagtttctgt
    11101 gaaataatct ttgattgtga acaaacaaag cataatttag agtattaaaa tctggaccct
    11161 gctatctatg gtaagtcttt ttgttattgt taaagaggtt aagcgtaatg ttaatatgtt
    11221 ttagctaaaa aatgtagtga aaaatgagta cgtagactat tgtaatagta attccgtaaa
    11281 attgttgaaa aagaaaatgg gaaatacctt gtcaaattaa gcaccctatg atagaataga
    11341 taggtatgtg gtgctagcac atccgtaaac atattctacg taggaggaaa tagatcaaaa
    11401 tggctaaagt atgttatttt acaggacgta aaaccgtttc tggaaacaac cgttcacacg
    11461 cgatgaacca aacaaaacgt acagttaaac caaaccttca aaaagttact atccttgttg
    11521 atggtaaacc taaaaaagtt tgggcttctg ctcgtgcgct taaatctggt aaagtagaac
    11581 gcatctaata gaaataagcc ttagggcttt ttttattagc ttatttctat ccataagcta
    11641 gtcaaggtaa taaacgctat cgttagcta
//
LOCUS       DAUGJR010000048         9935 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUGJR010000048 DAUGJR010000000
VERSION     DAUGJR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9935
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.048"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            26..2005
                     /locus_tag="VH800_001529"
     CDS             26..2005
                     /locus_tag="VH800_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEQ8362586.1"
                     /translation="MSILTSFTLLVTDVQADQVDVQFLGVNDFHGALDNTGTAYTPSG
                     KIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSALLQDEPTVKV
                     FNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEASHQTIVIAN
                     VIDKKTKDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEHYQFLDVA
                     ETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATVMEKVNQIYPEHSIDIIFA
                     GHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAPGIKTE
                     NSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLATTAQLTIAKK
                     TFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDVLNQ
                     QYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVNDFL
                     YGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGVKNYVTSNLESS
                     TKVNSAGKHSIISKVFRNRDGNTVSSEVISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     gene            complement(2087..2497)
                     /locus_tag="VH800_001530"
     CDS             complement(2087..2497)
                     /locus_tag="VH800_001530"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8362587.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            3214..3291
                     /locus_tag="VH800_001531"
                     /pseudo
     CDS             3214..3291
                     /locus_tag="VH800_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3389..5266)
                     /locus_tag="VH800_001532"
     CDS             complement(3389..5266)
                     /locus_tag="VH800_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8362588.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSADVKAIQLIRQ
                     YELLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFSDLKKEVHQDSSADKLEMTFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLKVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRVFYGNYSDYLDEKVFEKETVEADLAKTTVTEEVPLPQKEERKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(5263..6471)
                     /locus_tag="VH800_001533"
     CDS             complement(5263..6471)
                     /locus_tag="VH800_001533"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEQ8362589.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDIYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAITFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDYHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDR
                     INTLDQALVIHDKHDIVLNGSHLIKDFGMKSGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            complement(6596..7444)
                     /locus_tag="VH800_001534"
     CDS             complement(6596..7444)
                     /locus_tag="VH800_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8362590.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVFIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            complement(7444..7824)
                     /locus_tag="VH800_001535"
     CDS             complement(7444..7824)
                     /locus_tag="VH800_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEQ8362591.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            complement(7978..8228)
                     /locus_tag="VH800_001536"
                     /pseudo
     CDS             complement(7978..8228)
                     /locus_tag="VH800_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8727..9746
                     /gene="ideS"
                     /locus_tag="VH800_001537"
     CDS             8727..9746
                     /gene="ideS"
                     /locus_tag="VH800_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin G-degrading enzyme IdeS"
                     /protein_id="HEQ8362592.1"
                     /translation="MRKRCYSTSAAVLAAVTLFVLSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKDQIKRYLEEHPEKQKINFNGEQMFDVKEAIDTKNHQLDSKLFEYFKEKA
                     FPYLSTKHLGVFPDHVIDMFINGYRLSLTNHGPTPVKEGSKDPRGGIFDAVFTRGDQS
                     KLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGN
                     LKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDS
                     WNQTN"
     gene            9787..9935
                     /locus_tag="VH800_001538"
                     /pseudo
     CDS             9787..9935
                     /locus_tag="VH800_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3189 a         1993 c         1607 g         3146 t
ORIGIN      
        1 atattttatt ttaaaaagta gtgtattgag tatcctgact agttttactc tattagttac
       61 agatgttcaa gcagatcaag ttgatgtgca attccttggc gtcaatgatt ttcacggcgc
      121 tcttgataat accggaacag cttacacacc aagtggtaaa ataccaaatg ctgggacggc
      181 tgctcaatta ggtgcttata tggatgacgc tgagatagac ttcaagcaag caaatcaaga
      241 cggaacaagt atacgtgttc aagctggaga tatggtcgga gccagtcctg ctaactctgc
      301 acttttacaa gatgagccta ctgtcaaagt ctttaacaaa atgaaatttg aatatggcac
      361 tcttggtaat catgaatttg acgaaggact agatgaattt aaccgtatca tgacaggtca
      421 agcgcctgat cctgaatcaa caattaatga tatcaccaaa caatatgagc acgaagcttc
      481 gcatcaaacc atcgtcattg ctaatgttat tgataaaaaa accaaggata tcccctatgg
      541 ttggaaacct tatgctataa aagacatagc cattaatgac aaaatcgtta agattggctt
      601 cattggtgtt gtgactacag agattccaaa tctcgtttta aagcaaaact atgaacacta
      661 tcaattttta gatgtagctg aaaccattgc caaatatgct aaagaactac aagaacaaca
      721 tgttcatgct attgtggttt tagctcatgt tcctgcaaca agtaaagatg gtgttgttga
      781 tcatgaaatg gctacggtta tggaaaaagt gaaccaaatc tatcccgaac atagcattga
      841 tattattttt gcaggacata atcatcaata cactaatgga actatcggta aaacacgtat
      901 cgttcaagcc ctctctcaag gaaaagctta tgcagatgtc cgtggtacgc tagatactga
      961 taccaatgat tttattaaaa ctccatcagc aaatgttgtt gctgtagcac caggtatcaa
     1021 aacagaaaat tcagatatca aagctataat aaatcatgct aatgatattg ttaaaacagt
     1081 tactgaacga aaaatcggaa ctgcaactaa ttcttcaact atttctaaaa cagaaaatat
     1141 tgataaagaa tctcctgtcg gtaacttagc aacaacggct cagcttacta ttgctaagaa
     1201 aacttttcca actgttgact ttgctatgac caataatggt ggtattcgaa gtgacctagt
     1261 tgtcaaaaat gaccggacca tcacctgggg agctgcacag gctgtacaac catttggtaa
     1321 tatccttcaa gtcattcaaa tgactggtca acacatttac gatgtcctaa atcagcaata
     1381 cgatgaaaac cagacctatt ttcttcaaat gtcaggttta acatacactt atacagataa
     1441 tgatcctaag aactctgata cccccttcaa gatagttaag gtttataaag acaatggtga
     1501 agaaattaac ttaacaacta cttacaccgt tgttgtcaac gactttcttt atggtggtgg
     1561 tgatggcttt tcagcattta aaaaagctaa attaatcgga gctattaaca cagatactga
     1621 agctttcatc acatatatca caaatttaga agcatcaggt aaaactgtta atgctactat
     1681 aaaaggggtt aaaaattatg taacttcaaa ccttgaaagt tcgacaaaag ttaatagtgc
     1741 tggtaaacac agtatcatta gtaaggtttt tagaaatcgt gatggcaata cagtgtctag
     1801 tgaagtcatt tcagaccttt tgacttctac tgaaaacact aataacagcc ttggcaaaaa
     1861 agaaacaaca acaaacaaaa atactatctc tagttccact cttccaataa caggggacaa
     1921 ttataaaatg tctcctatta tgacaatcct tgccttgata agcttaggtg gactaaacgc
     1981 ttttattaaa aaaaggaaat cctagcgttt actagtaatc gatcaccctt atataatcag
     2041 gcatctttgc caaaaaaacc taaagcgtcc tactctaggt tttttgttaa attaaaatac
     2101 cttctagatg atctaattcg tgctggcata tttgagcagt taagcctgtt aagcttaatc
     2161 gctttggtcg ccaattatgg tccaaatact caacagtaat cttatcatac cgctgtgttt
     2221 tgcgatagcc agataacgac aaacaagatt ctttagtttg gtaaattccc tttttagaaa
     2281 ccatcacagg attaaacata accaaatcaa taaatcccat actcacaata acaatgcgct
     2341 tttgttcacc aatcatattg gcagccatcc caagacattc ctgtctataa aaggctaagg
     2401 tatcttgtaa atcttggcca atccatagat cttctttctt ggcgacttgc gctttttgct
     2461 gtaataaaaa atgatctgtt atgatttctc taatcattct tatctcctta aaccttcttt
     2521 ttaattcata aactacatgt tcaatggact attatcacta tatgatagac ttagtatcat
     2581 ctgtttaaaa catcaggtga ttccttattt caagatatct tgggcaactt tatgaaattc
     2641 tgcaatatga gtaccaaata aaaattgacc tgcatcagca gattgttaat aagttctcat
     2701 cacaatatta tcgaatttac tgtctgcttc ttcaaatgtc taagagagat agttattgct
     2761 ttgtgagatt ttcaaaccag atactgcttt ctcttgcatt tgcagccttg ataggtccaa
     2821 acaaaacacc tgctgtttga aatgctttaa tagctgatat gttgttaata gttagtatta
     2881 taaattttct gaatatttct gtcaagtttt tcagttgact taactttttt acttgatttt
     2941 tcctcacgta ataatagaaa agaagcgcca taatgtaaac tacaccccaa acgttagata
     3001 aaaaaatcta acgtttgggg tgtttttgta tgacattaag ctatgaagat aagctagata
     3061 tttagcgcta aaaaaaccga gggaactccg tttgaaagaa gcatctctgc aaagaagaag
     3121 acaaaaaacc attataaaga atggacaaag acgagttctg attaaatttt cttttaagaa
     3181 cggctaaatt gactcgttct acctactatt attatcgatt attgcaacaa taaccgtatt
     3241 aaaataaaac gaaaaggact tagtcctcta caacacagaa ctaaatcctt tacttcaaat
     3301 agagtagcca acttttgggg ctcagtgcaa gagcccttct tttctattat cacttgttta
     3361 ttataaacat aacattacca tagtatactt atatgtctag tccactcaaa tactcaaacc
     3421 gttcatacgc caataataaa tcattattgc gctgatcgag ttccttttgt aattgagcta
     3481 actggccata atcactaact acagttaaca tttggttttc aatttcttca atattagcct
     3541 caatagttgc tattttatct tctatctgag cccattcttg tttttcaagg taggacatgc
     3601 gctttctttc ctctttttga ggaagtggca cttcttcagt gactgttgtt ttagctaagt
     3661 ctgcctcaac tgtttctttt tcaaaaactt tttcatcaag gtaatcactg taattgccat
     3721 aaaaaacacg aatatcgcct tcttcaaagg ctaaaatctt agtagctact ttgtctagga
     3781 aataacgatc gtgactaacc gtaatgactg gtcctgcaaa gttagctaaa aagttttcta
     3841 agaccttcaa ggtggcaatg tctaaatcat ttgttggctc atcaaggaga agaacatttg
     3901 gcttttcaat gagcagtttt agcaagtaga gccgtttttt ctccccacca gataatttag
     3961 caatcagcgt gccatgactt gatctcggaa aaagaaattg ttctaaaagc tcactgatac
     4021 tcgttgttcc cacacttgtt ttaacctcat cagccacttc ttgaaggtaa ttaatgaccc
     4081 gtttggtctc atccatatct ttgagctgct gagagaaata acctacacga atagtatctc
     4141 caatatcaag cttcccagaa gttggtttga gatcaccgtt aatgatattt aacagggtag
     4201 attttccgac gccgttatct ccaacaattc caatacgatc tttattttga ataatcaagt
     4261 taaaatcctt aatcaactgt cggtcgccat aagcaaaaga aaggtcttca aagtgaatca
     4321 ccttcttccc aattcggctc gtttcgaaag tcatctccaa tttatccgca gaactgtctt
     4381 ggtgaacttc ttttttcaag tcactgaaac gattgattct agcctgctgt ttggttgcac
     4441 gcgcctgtgg ttgcgtcctc atccaggcta attcttgttt atagagttgc ttcttcttgt
     4501 gtaaattagc agcatctcgt tcgtcttgtt ctgcttttaa gcgcacatag tcttggtaat
     4561 tgccttgata ttctgtcagt cccgctttat ccaattcaaa aatacgggta gccacatgat
     4621 caaggaaata acggtcatgg gtaataaaaa ggacggtttt tttagctgtc ttgagatagg
     4681 ttgttaacca agcgatggtg tcaatatcga gatggttggt cggctcatcc aacaagagta
     4741 agtcagcagc tcctagcaac acttgagcta actggacacg tcttctcata ccacctgata
     4801 ggtctcccac tttttgttcc aaatccgtga tgcctaattt tgataggact gttttgacat
     4861 cactttcaat agaccaagca tctaatcgat ccatttcaga catgagggac tctaagcttt
     4921 cttgtttatc ctcagtataa ttcgccatca atagttcgta ctgacgaatc agttgaatag
     4981 ctttaacatc agctgataat accgtatcta aaacagaagc tgcatcgtta aattcagggt
     5041 cttgtgttaa gtaagcgatt ttgtaatcat tggctttaga aaatggtgaa tgatctccgt
     5101 caaaaccaag ccttcccgac aacacatcta aaagagttgt ttttcctgtt ccattaaccc
     5161 caataatccc aatacggtca aagtcatgaa taataaagga aatatcttga aagacggtct
     5221 tatctcccac cgtttttgtt aatttctcca ccaaaaaatg gctcatgttg ctaattcctc
     5281 tctaacaaat gcttcaattg tagtgaaatc attatctagg cgcccctcta caatcgctaa
     5341 ttcaactttc tcaagcataa gccctagctg aggacctgat ttcatcccaa aatccttaat
     5401 caggtgagaa ccattaagga cgatatcgtg tttgtcatga ataaccagtg cctgatctaa
     5461 agtattaata cgatccatgt caacggataa gctttgagct tttcggaggt cttccactag
     5521 actcgccatt ttcttgccgt actggtaaat atccaatttt tcaaaagatc tttcctgacg
     5581 aattctataa agagcaatca actttgtgac ataacgctga aaatcatttg aagtcttcca
     5641 tgcttttagg aagcttttag gatcctcaat ggctaaacta atcatcacat aagcccaagc
     5701 ttggtgataa tcactaaagg taaagttatc tttcaaagaa actatcagat gattcaagcc
     5761 tgcttcctgc tgcttcaagc ctggtaaata gtcgtaagcc tgacaagcaa tcatggcaga
     5821 aatccctttt cgccagtgcg gtgccatcaa taatttatca aattcagtaa aagaacgttc
     5881 cacagaaatc ttttccaata gaggtgaatg gctcctcata gcttcaaaag ttatagcttc
     5941 aatgtcaaaa tccagactcg ccgcaaatcg aaagcctctc ataatgcgta gtgcatcttc
     6001 ttcaaaacgt tcctctgctt tacccactgc tcgtaaccgt ttttgcttta aatcaatgag
     6061 tcctctaaat ttatcaataa cttgaccatt ttcatccaag gccaaggcat tgacggtaaa
     6121 gtctcttcgt tttaagtctt cctctaaaga gcgcacaaaa gaaacctgac taggacggcg
     6181 ataatcaaca tagatatctt ctgtcctaaa ggttgtaatt tcatactcac cgccattttc
     6241 aagcacgagc actgtaccat gttcaatgcc aacatcgaca gttctgttaa aaatcgcttt
     6301 agtctcttca ggataggaac tagttgcaat atctacatca tgaatgggac gctcgagtaa
     6361 aacatctctg acgcttcctc ccacaaaata ggcttcataa ccagcttctt ttattttagt
     6421 caatatgggt aaagccttct gaaactcaga aggcattgtc attaatttca tacgttgttt
     6481 tctaacctat catccaacta gcccaatcta aagtgtgatt aggctaattg ggttctatca
     6541 cattttgtta ttgttttagt gattcttgcc attaactatt ttttctaatc gacaattaaa
     6601 gcctcggtgt tacgccaaat gcaatggctc cttctcctaa atgagtagca atcaccgctc
     6661 caaaatgaac ctcttcaatg tcatattgat aaccactgtc ttgtaagagt cgtttcaaat
     6721 aatcagcttt gtcttgtgct tttgagtgaa taataaacac attatactga ccgtctgcta
     6781 tcaagtcatt taaaatctca accaagcgtt tcatggcttt cttttctgtt ctcacttttt
     6841 cataaacaac gatttttccc tcttcatcaa agcgtaaaat aggtttaata ctcaaaagat
     6901 ttccaagaag agcagaccca tttgacaggc gtccgccttt aaccagatga ttaaggtcat
     6961 caaccataat aaaggctgtc gtcccatcaa tctgttcttg cagcttgttt aaaatagctt
     7021 gaaatgtcat tccttgacgt gaccaatcta gcacattttt taccatacta cctaaaggag
     7081 cagatgtgat cttactgtct ggaaatgcca tttcaatctc aggatgttct tcagctaaaa
     7141 attgaatatt ttgccaaaag cctgagattc ctccagctaa gaacaagcca ataacatgtg
     7201 tataaccttt agaagataaa agtcctaaaa gattatctag ttcagataaa cttggctgac
     7261 ttgtcttggg aagattttgg gagtcagcca tcttttgata aaaatcatct atactcaaat
     7321 ttcgaccttc aaaataggtc tcatcgtcaa tgataactgg tatatcaagg ctaaaaatag
     7381 ctttatcttg tttcagatct gttggtagtg ttgctgtact gtcagtaatt actgctaatt
     7441 tcattaattt ttaaactcca aatgaatacc tggacgatcc aaggcaattt ctgtgacttc
     7501 ataagtcaat cgcttaacca tatctagcaa aggagcagct aaggattcaa cttcctcttg
     7561 cgtaaattcg cttggtttat ccactaaacg atctaaaata cgaaccattt gtgagatgac
     7621 cccactaata acaaattctt ctttgacaat aacaaattgc aatacagata caattactgt
     7681 ttctttttgc tgctcatctt tatcaatcaa ctgaaaagtc acttcaaaat tggtctctgg
     7741 tgttccgttt tctttttccc actctaaatt tctagcatca taatggtact ggttgacaaa
     7801 ttctttttca cgaactaatt gcatttttta ttctccttgg tatcaatatg atccattata
     7861 gcatagattt gaaaattatt aaagtagccc ctaaactact attttcgcat aacgttttaa
     7921 acagtgctat ctctcgaaca gatatctatt ttttcaccta tttatattta gtcgtcctta
     7981 tactgacatt ataccaaaaa aacacccgtt agtggtcttg tactgcacct caattaaaac
     8041 agaaccactg gtcaggtaag ttttaagtcc aggataaaaa ggtttatcac caaggcctca
     8101 tcatgcttag ccaagtattt cgaactagct tgtcttagct ctaatcgctc aaacgtaaac
     8161 cctaggcgtt caatccgccg caaaacctct ccaactaacc catacttaaa cccatagggc
     8221 ttaatcatcg ctccgccctt cttcttttat ccattataaa ataaaaacgt tttaacagac
     8281 aaaaaatagg aaagtaccag actattggat ttattttttt atctcaaact ccattaacga
     8341 tgttgagtta aaggcattca aaaccacata gatcgtaagc taacaagatt ttttatcaat
     8401 tgaacctatc gtccccagtt atacacgacc tcttctggat gaggtctttt tttatttgtc
     8461 taatttcatc aacgcttctt cccctctttc ttctatcaca gctctcctat tgctcacttc
     8521 ctcatgcagc aacatatcat caaaaaaccg ttcattttta agcacaacca ctactgtatc
     8581 tcttgtactg tctccattgc aatcgcatgt ttaattttat taaaaattat ttaaaaaaat
     8641 taaatattat tttaagaact tgcaataata tatgtctata ttatataatt tatttatcat
     8701 aaaattatat agaaaaaggt attcttatga gaaaaagatg ctattcaact tcagctgcag
     8761 tattggcagc agtgacttta tttgttctat cggtagatcg tggtgttata gcagatagtt
     8821 tttctgctaa tcaagagatt agatattcgg aagtaacacc ttatcacgtt acttccgttt
     8881 ggaccaaagg agttactcct ccagcaaact tcactcaagg tgaagatgtt tttcacgctc
     8941 cttatgttgc taaccaagga tggtatgata ttaccaaaac attcaatgga aaagacgatc
     9001 ttctttgcgg ggctgccaca gcagggaata tgcttcactg gtggttcgat caaaacaaag
     9061 accaaattaa acgttatttg gaagagcatc cagaaaagca aaaaataaac ttcaatggcg
     9121 aacagatgtt tgacgtaaaa gaagctatcg acactaaaaa ccaccagcta gatagtaaat
     9181 tatttgaata ttttaaagaa aaagctttcc cttatctatc tactaaacac ctaggagttt
     9241 tccctgatca tgtaattgat atgttcatta acggctaccg ccttagtcta actaaccacg
     9301 gtccaacgcc agtaaaagaa ggtagtaaag atccccgagg tggtattttt gacgccgtat
     9361 ttacaagagg tgatcaaagt aagctattga caagtcgtca tgattttaaa gaaaaaaatc
     9421 tcaaagaaat cagtgatctc attaagaaag agttaaccga aggcaaggct ctaggcctat
     9481 cacacaccta cgctaacgta cgcatcaacc atgttataaa cctgtgggga gctgactttg
     9541 attctaacgg gaaccttaaa gctatttatg taacagactc tgatagtaat gcatctattg
     9601 gtatgaagaa atactttgtt ggtgttaatt ccgctggaaa agtagctatt tctgctaaag
     9661 aaataaaaga agataatatt ggtgctcaag tactagggtt atttacactt tcaacagggc
     9721 aagatagttg gaatcagacc aattaaagcg tatcaataag aaagattacc ttcaacagat
     9781 gatggtattc taaggactaa tactattgca gggaattttt ttatagatgg gcaacagcaa
     9841 aaacattaat aaatcctata aaaatcgata aggatattgt tacgattcaa gagttcgatt
     9901 ttaaaataag aaaatttttg atggaatcaa aagaa
//
LOCUS       DAUGJR010000049         9808 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUGJR010000049 DAUGJR010000000
VERSION     DAUGJR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9808
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.049"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(264..1406)
                     /locus_tag="VH800_001539"
     CDS             complement(264..1406)
                     /locus_tag="VH800_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEQ8362593.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLVALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITSNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFCQTTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
     gene            1688..4666
                     /locus_tag="VH800_001540"
     CDS             1688..4666
                     /locus_tag="VH800_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEQ8362594.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRYLTNTFRNSRWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLDSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLMKKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIVYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            4679..5878
                     /locus_tag="VH800_001541"
     CDS             4679..5878
                     /locus_tag="VH800_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8362595.1"
                     /translation="MTKSKQPQYRFDGFEGEWEEKELGDIVQITMGQSPSSQNYTTNP
                     SDYILVQGNADIKNGYVFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIGRG
                     VAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIPSLPEQEAIGE
                     LFQMVDQLIQLQDQKLATLKEQKQTFLRKMFPAQGQKVPEIRLQGFKGEWEEKKLREV
                     STHRSGTAIEKYFDSEGEFKVISIGSYGTNNLYVDQNIRAVSNELTNSKLVASGELTM
                     VLNDKTANGAIIGRCLLITENNKYVVNQRTEIIRPDINISSYYLFHYLNGEFRNGIIK
                     IAQGGTQIYVNYSSVEQLKINIPTLKEQEAIGNFFQTLDQQIAQSEEKLTELKALKQT
                     LLNRLFV"
     gene            5891..7471
                     /locus_tag="VH800_001542"
     CDS             5891..7471
                     /locus_tag="VH800_001542"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEQ8362596.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLLAVCDNLEKHFNTFTEAQKIFEDAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPINFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDNHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(8024..8629)
                     /locus_tag="VH800_001543"
     CDS             complement(8024..8629)
                     /locus_tag="VH800_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8362597.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLANISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(8610..>9808)
                     /locus_tag="VH800_001544"
     CDS             complement(8610..>9808)
                     /locus_tag="VH800_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362598.1"
                     /translation="QFKDKLDKGLLIIIFVSITSLFVNRILFNFLFLMVFTILHLYPL
                     LVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEMLDVNQAFNNLGWYLFPLI
                     MSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWIVLMKVLVKDFLLFFIVV
                     DASTLFCLVVISCIFYYLENSKQNFDYENRRLNYFMKSEENMRVEFSNYLHDDVLQNI
                     IAIKNLFSLENSNITHGFIVNELNDLVSGIRDEMDTYHPIVPANQTMKENIQSLFDDI
                     VKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSLTIQSDI
                     IIIEESNQVVEKVHSINYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLPIDWKLC
                     YEDFIN"
BASE COUNT         3342 a         1847 c         1634 g         2985 t
ORIGIN      
        1 acgtctccta agagacaact tctttattct atcaggtttc tcatagcctg tcaactactt
       61 tttcatcttt tttcaataag tgtgttacag gaacctctct gacagcttta ttagtatacg
      121 atatctttac tgtcattgtc aactcttttt tacaaaatgt ttctgttttt catactatgc
      181 taatgagtta gctcgtgcgt ctccttcttc ataggttact tttaaccacc aaatgaatgc
      241 tacacaatcg aaaatagatg agtttactta ttaaactgag ctatcaatag cataaggtta
      301 gctgctaata ttttgatatt agaaagtgtt gttgttttat ctatcgctgc ttctaaggaa
      361 attggctgct gttgtattga aaaaacagcc aaaaagtctt ctgctgctag tcctgtctca
      421 atctttacag aaccacatag agcaatcgtt ggaacttgat attttttagc cattcttgca
      481 atcgcaacag gtaccttgcc agattgtgat tgtgtatcca ggcatccttc tccagtaata
      541 actaaatcac aagactgaag ggaattatcc agatttagta gctctgcaat cctgctaaaa
      601 ccactagtta aggtgcctcc taataggaca atggcacctc ctaatcctcc agctgctcca
      661 cttcctggta ttgtctgtaa atcaatggtt gtttggcaaa aaactttttt agcaaagtta
      721 cttgcaattt gatcagtttc ttcaatttga ctaagactcc cacctttttg agggccaaag
      781 accgcagcaa atccttgagg gccatgatat ggattggtca catcagtcag ccctaatagc
      841 gtaacaggtg atgctaaagt atcaagataa gatcttcctg tcatgaaatc atagtttaaa
      901 ctttccaaaa accctttgcc accatcagaa gtgcctgtgc ctcctagcat gatttcgatt
      961 tgagtagctc ctttttgaat ggcatcttta actgccaaac ccaaaccgta ggaagtggct
     1021 tgtgcatagg ttactgaatt ggaggtgatc ttatcaatac caataatact cgcagattca
     1081 ataaaagctt gctttgcgtg acgataataa gcgactttaa tcgggcgtct taatagatca
     1141 atggttttta cttgatgcca cctccccgcc acggtttgtg agagggctac taaacttcct
     1201 tctcctccat cagcgatagc tcttgtttca ataactaact gcttatcgac agaaagaagg
     1261 gcttgagcta cactagtgtt aagttctgga gacgttaccg atcccttaaa agaatctatg
     1321 gctaccaaaa ttttcatatc ttcaataaat tccttttctg tatattgtag cagattatca
     1381 tcctttaaaa ccctattaat agtcaagcta gatctgtctt aagtttttta tctattttga
     1441 gaactcgacc tttttactag tgttgtctta ttactttctt caccttaaat tattgtcaag
     1501 caaactcaaa aatacaagaa ctttctcgat tgcatttaca tagtcatagc tttgtttagc
     1561 tgctaggatc ttaagcattc aactaatcaa aaaaaagact gtttggaagg tttcaatagc
     1621 ttcgccattc taaaaaggat ccgccaatga tataatatta ctatatcatg tcgaatgggg
     1681 attaaaaatg ggaaatcaaa ctaaaacgga acttgaactt gaaaaagagt tgatccatct
     1741 cttagaaaca ggtgaaagtc aatggacata tcgtaaagaa ttaaaaactg aagatgcttt
     1801 atgggataat ttctttaaga tcttagcgca aaataacacg caatatctga acgaggagcc
     1861 tttaacagct agtgaaaaag agcagattaa gaatcaactt aactttgtca attactatga
     1921 agcggctaaa tggttagctg gtgaaaacgg cattgctaaa gtacaagtgc aacgcgaaga
     1981 tgcaaaacta ggaacgattc gtttagaagt cgttaaagca gacaatgtgg ctggtggaac
     2041 ttctgtttat gagattgcca atcaagttgc tttctctggt tctcgtgata gacgaggtga
     2101 tgtgacactt ctcatcaatg gcttacctat gatccaaatt gaattaaaat ctcagaatca
     2161 tcaatgcatt gaagctttta accaagtcaa aaagtatgat aaagaaggcc agtttagagg
     2221 tatcttttca accttacaaa tgtttgtggt ctcaaataaa acagatacaa ggtatatcgc
     2281 tgcagctaaa gaaaataaat taaaccctaa cttcttgacc caatgggtag atcaaaacaa
     2341 caaaccacaa aaagatctct ttgcctttgc caaagaagtc ctatctatcc ctcgtgctca
     2401 ccaaatggtc atgacttact ctgtcattga tgatgataaa aaagcactaa ttctccttcg
     2461 tccttatcag attcatgcaa tcgaagccgt cgctgaagcg agtcgtcacc gcaagtctgg
     2521 ctatatctgg cacacaacag gttctggaaa aaccttaact tcctataaag tggctcgcaa
     2581 tatccttcaa ataccggccg ttgaaaaatc catctttgtc attgaccgaa aggatttaga
     2641 taatcagacc gcttctgctt ttcaatccta tgcgcaaaat gatatctttg atgtcgatga
     2701 gacagaagat acgagacaac tcatcaaaaa tttagaatcc agcgatcgtc gtgttgtggt
     2761 caccaccatt caaaaactca atgccatgat cagtcagatg gaaagttatg acactccaaa
     2821 attcaagaaa ctaaaagagc gtcttgcaca cttaaatgtt gtctttgttg tggacgaatg
     2881 ccaccgtgct gtcacgccag aacgtcaacg ttatctcacg aatacttttc gtaacagtcg
     2941 ctggtatggc tttaccggca ctcctatctt tgtggaaaat aagcgtgctc aattaggtga
     3001 tttagcccaa acaacggaac agcaatacgg caaatgtctc catcaataca ccgttaaaga
     3061 agccattcat gataaagcgg ttctaggctt tcaagttgag tataagacaa ccattcctga
     3121 tatgcctgaa gacagtattc cggaagaagc ttatgatcat gaagaacata tgttagctgt
     3181 cttagatagt atcattaatc aatcacgcaa gaaacttggt tttaataatg gaattggtca
     3241 gacattcgaa ggtttactaa ccgttaagag tattgctcgt gcccaagcct attatgatct
     3301 gatgaagaaa gttaaggctg gtgaaacgga tttagtcatt tctaagaagg tcaaagaaaa
     3361 actaccagac tttccaaagg tagctattac ttattctatc actgaaaatg acaatgcgtc
     3421 tatcagccga caagataaaa tgaccaaaaa tctagaagac tataatcacc tctttggcac
     3481 taactttacc atcgataact tacaaggcta taacagagat ttaaatgatc gcttagcccg
     3541 taaaaaagat aaattcaaag accgtcatga acaattagac ctcgtgattg tggttgaccg
     3601 tctcttaaca ggttttgatg cgccttgttt atcaacgatc tttattgatc gccagcctat
     3661 gaaacctcag cacattattc aagctttctc acgaaccaac cgtatctttg aaagtagaaa
     3721 acattacggt caggttgtga ctttccaaac accacttcgt tttaaagaag ctgtcgacaa
     3781 agcgcttagc ctctactcta atgggggtga aaacgacgtt ttggcccctt cttgggaaga
     3841 agaaaaagca agattctttg aaaaagtaac agtattaaaa aatatagttc ctgatccaga
     3901 cgctttccca actattgaga gcgcacagac agcttttctc aaacaatacg ccaaagcctt
     3961 tcaagcgttt gataaactct ttgcatctgt acaggtctat agtgatttta atgaaacact
     4021 gttgagtgag gttgggttat cagatgaagt gattgatact tataaaggca cttaccaaaa
     4081 tgtcattgca gaaatacgaa agcgaagaga agatgacgaa gccatcccag agatcaatat
     4141 cgactatgag ctagaaagtg ttcagatgga tgatatcaac tatcactata tcttgacctt
     4201 aattcaagcc tttgtcgatc aagaacaaga agctcttcaa gaaaggctca atgacaatcc
     4261 tatggatcaa tacatccaag atttggcaaa atcaaaccct gctatggctg actcactagc
     4321 tgagttatgg caagatatcc aaaaagaacc caaagcctat gaagggaaaa gcattgttta
     4381 tgagttagat aacctcattg gtgataagat ccaaagggcc atcaaacact ttgcggacca
     4441 atggaaggca gatcctgaca aattagcctt tgtggcgact aattatcata gtgctaactc
     4501 taccaaacaa gtgggcatgt caaccttaaa agaatcccta gactaccaag cctataaaga
     4561 aaaacaaggt gattctgcca tgaataaact caaatacaag agccaatttg aacgggagtt
     4621 agttcaattc attagagatc aaatccaacc cttaaaaggg cactaggaaa ggaaagagat
     4681 gacaaaatct aaacagcctc aatatcgctt tgacggtttt gaaggggagt gggaagaaaa
     4741 agaactaggg gatattgttc aaattacaat gggccaatct ccatcaagtc aaaattatac
     4801 tacaaaccct tctgattata ttctagtaca aggaaatgcc gatataaaaa atggatatgt
     4861 ttttccgcgt gtctggacaa cacaaattac aaaacaagct gacaaaggtg atattattct
     4921 tagtgttagg gctccagttg gtgatgttgg aaagacaaat tatcatgtta ttattgggcg
     4981 tggagttgct gctataaaag gtaatgaatt tatctttcaa atattaaaat acttgaaaga
     5041 aattggttat tggaaaagaa ttagtacagg ttcaactttt gatagcatta gctctagtga
     5101 tatcaaatat gctaaaattc aaattccctc cctccctgaa caagaagcca ttggcgaact
     5161 tttccaaatg gttgatcaat tgattcagtt gcaggatcaa aagctagcaa cccttaaaga
     5221 acaaaagcaa accttcctca ggaaaatgtt cccagctcaa ggacaaaaag tccctgaaat
     5281 ccgtttacaa ggttttaaag gagagtggga agagaagaaa ttgagggaag tatctactca
     5341 tagaagtgga acggcaattg aaaaatattt tgattcggaa ggtgaattta aagtcatttc
     5401 aataggtagt tatggaacta ataacctcta tgtagaccaa aatattagag cagtctcaaa
     5461 tgaacttact aattctaaat tagttgcctc cggtgaatta acaatggtac tcaatgataa
     5521 gacagcgaat ggggcaataa tcggaagatg tctacttatt acagaaaata ataaatacgt
     5581 tgttaatcaa agaacagaaa ttattagacc agatattaat atttcctctt actatctttt
     5641 ccattattta aatggcgaat ttcgtaatgg tatcattaaa attgctcaag gtggcactca
     5701 aatctatgta aattattcat ctgttgaaca attaaagata aatataccta cattaaaaga
     5761 acaagaagcc attggtaatt tcttccaaac tttagaccaa caaattgctc aatctgaaga
     5821 aaaactaaca gaactcaaag cactcaaaca aacattactc aatcgtttat tcgtataaga
     5881 aaggactcac atggcagaga aaacaacttc actccgtcaa gcactatggc attcggccga
     5941 ccaattacgt ggccaaatgg atgccaatga ctataaaaac tatcttcttg gacttatttt
     6001 ttacaaacac ttatctgata aattactctt ggctgtttgt gataatctag aaaaacactt
     6061 caataccttt acagaggctc aaaaaatctt tgaagatgct tatcaagatg aaggcctaaa
     6121 agatgacctc atttctgttg ttactggtga tttaggttac tttatcgaac cgacactgac
     6181 ctttgaaaaa ctcatccaag atgtttatca caatactttc caattagaat cattagctca
     6241 aggttttcgc gatattgaac aaagtggtga agactttgaa aacttatttg aagatattga
     6301 cctctactct aaaaaattag gctctactcc tcaaaaacaa aatcaaacca tttctaatgt
     6361 catgaaaaca ttaaatgaaa ttgactttga ggcagtagat ggggatactt taggtgatgc
     6421 ttatgagtac ttgattggtg aatttgccag tgaatcagga aaaaaagcag gtgagttcta
     6481 taccccacaa gctgtctctc acttaatgac tcagattgtc tttttaggtc gtgaagatca
     6541 aaaaggaatg accctctatg accctgctat gggatctgga tcactccttt taaatgctaa
     6601 gaaatatagt aaccaatccg ataccgtttc ttactatggt caagaaatca atacttctac
     6661 ttataacttg gctcgtatga acatgatgct tcatggcgtt gccatcgaga accaacactt
     6721 aagtaacgct gataccttgg atgcagactg gccaacagat gaaccaatca actttgatgg
     6781 ggtgttgatg aacccacctt attctttgaa atggtcagcg actgctggtt tcttaacgga
     6841 tccacggttt tcaagttatg gtgtattagc accaaaatca aaagccgatt ttgccttttt
     6901 acttcatggt ttctatcatt taaaaaatac aggaactatg gcgattgtct taccacacgg
     6961 tgtccttttc cgtggagctg cagaaggcaa gattcgccaa aaactactcg aacaaggggc
     7021 tatcgatacc attatcggac tcccatcaaa tatcttttat aatacaagca tccctacgac
     7081 tattatcata ttaaagaaga acagaaccaa caaagatgtc ttctttatcg atgcttcaaa
     7141 agagtttgat aagggtaaaa atcaaaacac aatgacagat aaccatatca aaaagatcct
     7201 tgatgcttat aagagtcgtg ataattctga taagttttca tatttagcct catttgatga
     7261 aatcattgaa aatgactata acttaaatat cccacgctat gttgatacct ttgaggaagt
     7321 cccagttaaa ccactgccag aattagctaa acagctcagt gacattgatc aagaaattgc
     7381 caaaacaaat gccaaactag atcaactcat gaaacaacta gtcggaacaa ccaaagaagc
     7441 acaagacgaa ttggatactt ttagaaacta aaagacaaaa aaacaccaca gtagatgatt
     7501 actactgtgg cgttttattt aaaattgagt agtgaacctt tattgagtac ttatcaaaca
     7561 agattctcct tcttcaccta taaatcaaaa tagaatcatc tcatctaact ttgtccgttt
     7621 ctttgtttta tttaaaatag ttatttgaag ttacaatgat ttctcaaacg tttagaaatc
     7681 ttaaacacgg ttaagagaaa ttttcaggac aacttttgat ccttccacaa aaaccatggt
     7741 gcgaaccata aagtagttcc aatcgttgat atataagcat atattaacgt tctgggagtt
     7801 gtgaagcttt acaagttttt ttagacctgg tttaaacaac ttttgtttga ctaaatttaa
     7861 aaagcttttc atatcaggca tttccctact ttttataaaa gcgttatctc aatcaatttc
     7921 aatcaaaaag aactaaaaaa acaatgagtt taaatctggg tatttaacag gaaatcccta
     7981 gcaacgacac aagtaaaact tatgtcgttt gattatctgc aactcagaaa tccataaaat
     8041 accctaattg ttcggctttg tagatagcct cctgcttatt atttaccaaa agctttgagt
     8101 agatgtgggt caaatgatta aatactgttc tcctactaat ttgtaacgtt tcctctattt
     8161 cttttataga gaatcctttc ttactcaaat ttaagatagc tatttcctgg tcagttaaag
     8221 attcaacata atcctgagat tcgatttgtt caaaatactt ttttccagaa tccacttttt
     8281 ttaagataga aatgagttgt ttagggtcta tatttttatc tacaaaaccg tatgctccta
     8341 ctttttttgc cctctctcta tagattgatt taacatatcc tgtcaacata acaactttca
     8401 aatgaggagt agactgtatg agttcttttg ctatctccaa tccattttct ttagaaatat
     8461 ttgctaaatt aatatcaagc aatataatat cgtacttaga caaatcaatc gtcacatcgt
     8521 taaaatgaga agtaatcgta tctatgacat ctacttcatc atactgttgg aataacagtt
     8581 ggatactctt tgcaaatagt ctgtggtcat caattaataa aatcttcata acacaatttc
     8641 caatctatgg gaagtaatat tctgatagta aattgtttag tatccatttg tagttctaga
     8701 tctccatcaa aagctgctag tgtttcttga aatgatttca atcctctgcc ataatttata
     8761 gagtgtactt tttccactac ttgattgctc tcctcaatga taataatatc agattgaatc
     8821 gttaaagata aacgaatgtc ttttccatct ccatatttta tagcattgtt tattagctct
     8881 tttataaacc tataaacaat atctccatat ggggatggca ctaccatatt atctgaacag
     8941 ttaaaataca ataaggtatt actttttcta cttttaacaa tatcatcaaa aagagactgt
     9001 atgttttctt tcattgtttg attagcggga actattgggt ggtaagtatc catttcatct
     9061 ctgataccag aaactaaatc attcaactca ttaacaataa aaccatgtgt tatattacta
     9121 ttttctagag aaaacaagtt ttttatcgct atgatatttt gtaaaacatc atcatgcaaa
     9181 taatttgaga actccactct catgttttcc tctgatttca taaaatagtt cagtcttcta
     9241 ttttcatagt caaaattttg tttggagttt tctaaataat aaaagatgca agaaattacc
     9301 actagacaaa acaacgtgct tgcgtcaaca actataaaaa atagcaaaaa atctttaact
     9361 aataccttca tgagtacaat ccaacaaagg ataagaagta gaaataatag ttctatacga
     9421 gctttgtaat cacctaacca tctttgggta acaaaactca atttatcatg tatggtctta
     9481 aaatagtata ttacactcat tataagggga aacagatacc atcccaaatt attaaaggct
     9541 tgattaacat ctagcatttc tccataaagt tcactaccaa gtattaccag caaaagtaaa
     9601 gaaaatagta tcaatgaacg tctaacaact gatatttgtt gcctaaagga cctataatat
     9661 agcactataa ctagtaacgg atacaggtgt aaaatagtaa aaaccatcag gaataaaaaa
     9721 ttaaataaaa ttctattaac aaaaaggcta gttatagaaa caaaaataat tattaacaag
     9781 cccttatcta acttatcttt aaattgtt
//
LOCUS       DAUGJR010000050         9757 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUGJR010000050 DAUGJR010000000
VERSION     DAUGJR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9757
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.050"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..839
                     /gene="dnaN"
                     /locus_tag="VH800_001545"
     CDS             <1..839
                     /gene="dnaN"
                     /locus_tag="VH800_001545"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ8362599.1"
                     /translation="QHQVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKS
                     IIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVV
                     IPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEF
                     ETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIV
                     SQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVR
                     TN"
     gene            914..1111
                     /locus_tag="VH800_001546"
     CDS             914..1111
                     /locus_tag="VH800_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEQ8362600.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            1441..2556
                     /gene="ychF"
                     /locus_tag="VH800_001547"
     CDS             1441..2556
                     /gene="ychF"
                     /locus_tag="VH800_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEQ8362601.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREIDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            2626..3195
                     /locus_tag="VH800_001548"
     CDS             2626..3195
                     /locus_tag="VH800_001548"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEQ8362602.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            3198..6701
                     /gene="mfd"
                     /locus_tag="VH800_001549"
     CDS             3198..6701
                     /gene="mfd"
                     /locus_tag="VH800_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEQ8362603.1"
                     /translation="MDILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKTLAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSGLRILLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GIFINPASDLIFEVSDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFTDNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQISSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYIADERQK
                     IDIYKRIREIQSREDYLNLQDELMDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            6863..7135
                     /locus_tag="VH800_001550"
     CDS             6863..7135
                     /locus_tag="VH800_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEQ8362604.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            7122..7493
                     /locus_tag="VH800_001551"
     CDS             7122..7493
                     /locus_tag="VH800_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEQ8362605.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKSTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            7628..8914
                     /locus_tag="VH800_001552"
     CDS             7628..8914
                     /locus_tag="VH800_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEQ8362606.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQIPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFLFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            8911..>9757
                     /gene="tilS"
                     /locus_tag="VH800_001553"
     CDS             8911..>9757
                     /gene="tilS"
                     /locus_tag="VH800_001553"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8362607.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTA
                     KQGYYY"
BASE COUNT         3451 a         1452 c         1792 g         3062 t
ORIGIN      
        1 aacaacacca agttgtttta accagtggta aatcagagat taccttaaaa ggaaaagatg
       61 ttgaccagta tcctcgtcta caagaagtat caacagaaaa tcctttgatt ttaaaaacaa
      121 aattattgaa gtctattatt gctgaaacag cttttgcagc cagtttacaa gaaagtcgtc
      181 ctattttaac aggagttcat attgtattaa gtaatcataa agattttaaa gcagtagcga
      241 ctgactctca tcgtatgagc caacgtttaa tcactttgga caatacttca gcagattttg
      301 atgtagttat tccaagtaaa tctttgagag aattttcagc agtatttaca gatgatattg
      361 agaccgttga ggtatttttc tcaccaagcc aaatcttgtt cagaagtgaa cacatttctt
      421 tttatacacg cctcttagaa ggaaattatc ccgatacaga ccgtttatta atgacagaat
      481 ttgagacgga ggttgttttc aatacccaat cccttcgcca cgctatggaa cgtgccttct
      541 tgatttctaa tgctactcaa aatggtactg ttaagcttga gattactcaa aatcatattt
      601 cagctcatgt taactcacct gaggttggta aggtaaacga ggatttagat attgttagtc
      661 agtctggtag tgatttaact atcagcttca atccaactta ccttattgag tctttaaaag
      721 ctattaaaag tgaaacagta aaaattcatt tcttatcacc agttcgacca ttcaccctaa
      781 caccaggcga tgaggaagaa agttttatcc aattaattac accagtacga acaaactaag
      841 taagaaaaag ctccctttta ggagtttttt tgttattata aatattaacg ataatataag
      901 tggagaaaag ggaatgtatc aaattggatc atttgttgaa atgaaaaaac ctcatgcttg
      961 tgtaattaaa gaaactggta aaaaggctaa tcaatggaag gtactgagag taggagctga
     1021 tattaaaatt cagtgtacta actgtcagca tgtgattatg atgagtcgtt atgattttga
     1081 gcgaaaatta aaaaaagtac tgcaaccatg aaagtccttt taaataaata attctagcta
     1141 tatttgcaac caatactttg ctaaaaaatt gctagtatgc cgttggaaaa ttagctattc
     1201 taatgttatc gaaagaagaa agatggccat tgacaatgac gaaagttgta gcacagttac
     1261 ttagtttctc ggcaaactat atcaaaatga gaataataca ccaaactttg ataatttaaa
     1321 tgaaggtgaa agagtggcat aatgataagc aaatctgaaa ttttcttctt attcataccg
     1381 ctttttcttc tattttttgg tataataatc ttgattgaaa tttgaatgga gattcgctaa
     1441 atggctttaa cagcaggtat tgtaggctta ccaaatgttg gtaaatcaac cttatttaac
     1501 gcaattacaa aagcaggagc agaagctgct aattatcctt ttgcgactat tgatcccaat
     1561 gttggtatgg tagaggttcc agatgagcgt ctgcaaaaat tgacagaatt gattacacct
     1621 aaaaaaacag ttccgacaac ctttgaattt actgatattg caggtatcgt taaaggtgct
     1681 tctagagggg aaggtctagg aaataaattt ttagctaata ttcgtgaaat cgatgctatt
     1741 gttcatgtgg tacgtgcttt tgatgatgaa aatgtcatgc gtgaacaagg tcgtgaggat
     1801 gctttcgttg atcctatagc agatattgac actattaatc ttgaattaat cttagctgat
     1861 ttagagtcaa tcaataaacg ttatgcgcgt gttgaaaaaa tggcacgaac tcaaaaagat
     1921 aaagaatcag tagcagagtt taatgttttg caaaagatta aacctgtttt ggaagatggg
     1981 aaatcagcta ggacaattga gtttacagaa gatgaagcaa aagttgttaa aggtctcttt
     2041 ttattaacaa ctaaacctgt tttatatgta gctaatgtcg atgaagataa agttgctaat
     2101 ccagatggta ttgattatgt caaacaaatt cgtgactttg cagctactga aaatgctgaa
     2161 gtagttgtta tctcagcgcg tgcagaagaa gaaatttcag agcttgacga tgaggataaa
     2221 gaagaatttt tggaagctat cggtcttact gaatcaggcg ttgataaatt aaccagagca
     2281 gcttatcatc tcttaggcct tggaacctat tttacagcag gtgaaaaaga ggttcgtgct
     2341 tggacgttta agcgtggtat aaaagctcca caagctgctg gtattatcca ttcagatttt
     2401 gaaagaggtt ttattcgtgc agtaaccatg tcttatgatg atctaatgac ctacggttca
     2461 gaaaaagccg tcaaagaagc tggacgcttg cgtgaagaag gaaaagaata tgttgtccaa
     2521 gatggggaca tcatggaatt cagatttaat gtgtaattat attaaaacaa tatcagaagg
     2581 ttggaagaac attccagccc ttttggcatt ttagaaagag aaaatatggt aaaaatgatt
     2641 gttggtctgg gaaatccagg ctctaaatat gaaaaaacaa agcacaatat tggttttatg
     2701 gctattgaca atattgtcaa gaaccttgac gttaccttta cagatgataa aaattttaaa
     2761 gcacagatag gaagtacttt tattaatcat gaaaaagttt actttgtgaa acctactact
     2821 tttatgaata atagcggcat agcagtaaaa gcattactaa cctactataa tattgacata
     2881 acagatttaa ttgttatcta tgatgattta gacatggaag tcagtaaatt acgtttacgt
     2941 agtaagggtt cagcaggagg acataatggc attaagtcaa tcattgccca cattggaact
     3001 caggaattta accgaatcaa agttggtatt ggacgacctt taaaaggtat gactgttatt
     3061 aaccatgtga tgggccaatt caataccgaa gataatattg ctatttcgtt aactcttgac
     3121 agagttgtca atgctgtcaa gttttattta caagaaaatg attttgaaaa aacaatgcag
     3181 aaatttaatg gataatcatg gatattttag aattatttag tcagaataag aaagtccaat
     3241 cctggcactc tggattaacc accttaggaa gacaactggt aatggggtta tcgggttcaa
     3301 gtaaaacatt ggctatagct tccgcttatt tagatgatca aaaaaaaata gttgtggtta
     3361 catcaactca aaatgaggtt gaaaaattag ccagcgattt atctagttta cttgatgaag
     3421 aacttgtttt ccaatttttt gcagacgatg tggctgcagc ggaatttatc tttgcgtcaa
     3481 tggataaagc tctatcaaga atagaaaccc tgcaattttt aaggaatcct aaatctcagg
     3541 gcgttttaat tgttagttta tcaggcttaa gaattttatt gccaaaccca gatgttttta
     3601 caaagagtca gattcaacta acagttggag aagattatga tagtgatact cttactaaac
     3661 aactgatgac aattggctat cagaaggtct cacaggttat tagtccagga gaatttagcc
     3721 gtcgagggga tattttagat atctatgaga ttacacaaga attgccttat cgattggaat
     3781 tttttggcga tgatattgat agtattaggc aatttcatcc agaaactcaa aaatcttttg
     3841 aacaactaga aggtattttt attaatccag caagtgatct tatttttgag gttagtgatt
     3901 ttcaacgtgg cattgagcaa ttagaaaagg ctctacaaac agcacaagat gataaaaaat
     3961 cttatttaga agatgtatta gctgtttcaa aaaacggttt taaacataag gatatccgta
     4021 aatttcaatc attattttat gaaaaagagt ggtcattatt agattatatt cctaagggaa
     4081 cgccaatctt ttttgatgat tttcaaaaac tagttgataa aaatgcaaga tttgatttag
     4141 agattgctaa tctcttgaca gaagatttac agcaaggaaa ggctctttcc aatcttaact
     4201 actttacaga taattatcga gagcttaggc actataagcc agcgaccttc ttttcaaatt
     4261 ttcataaggg acttggaaat atcaaatttg atcagatgca tcagctaact cagtatgcca
     4321 tgcaggaatt ttttaatcaa tttcctttgt tgattgatga gattaaacgg tatcaaaaaa
     4381 atcaaacaac ggttattgta caggtagagt ctcagtatgc ttacgaacga cttgaaaaat
     4441 cttttcaaga ttaccaattt cgccttcctt tagtgagtgc taatcaaatt gtttcacgtg
     4501 aatcacaaat tgtaattgga gctatctcca gtggttttta ttttgctgat gaaaagttag
     4561 cgttaatcac agagcatgaa atttatcata aaaagatcaa acgacgcgct agacgatcta
     4621 atattagcaa tgctgagcgt ttgaaagatt acaatgagtt agcagtaggt gattacgtgg
     4681 ttcataatgt ccatggtatc ggtcgctttc ttggaattga aacgattcag attcagggaa
     4741 tccatcgaga ttatgttact attcaatatc aaaattcaga ccgtatttct cttccaattg
     4801 accaaattag tagcttatca aagtacgttt ctgctgatgg aaaagaacct aaaattaata
     4861 aactcaatga tggtcgtttt caaaagacaa agcaaaaggt cgctagacaa gtagaggata
     4921 ttgctgatga ccttctaaaa ttatatgctg aaagaagtca gcaaaaagga ttttcatttt
     4981 caccagatga tgacttgcag cgcgcttttg atgatgattt tgcttttgta gaaacagaag
     5041 atcaacttag gtctataaag gaaattaaag ctgatatgga gagcatgcag cctatggatc
     5101 gtcttttagt aggcgatgta ggatttggta agacagaagt agctatgagg gcagccttta
     5161 aagcggtgaa tgatcacaaa caagtagctg tcttagttcc aaccacagtc ttggcccagc
     5221 agcattatga aaacttcaaa gcacgctttg aaaattaccc tgttgaggtt gacgtcttaa
     5281 gtcgtttccg tagtaaaaaa gagcaagctg aaacactaga acgtgtacga aaaggtcaaa
     5341 ttgacattat tatcggaacc catcgactcc tatcaaaaga tgtggtcttt tctgatttag
     5401 gattgattgt gattgatgag gaacaacggt ttggtgttaa gcataaagaa actttaaagg
     5461 aattaaaaac taaggttgac gtcttaacct taacagctac tccgattcct agaaccttac
     5521 acatgtctat gttaggtatc cgagatttat cggttattga gaccccacca accaatcgtt
     5581 atcctgttca aacctatgtt ttggaaaata atccaggtct cgttagagaa gctatcattc
     5641 gtgaaatgga tcgcggagga caaatttttt acgtttacaa taaagttgac actattgaaa
     5701 agaaagttgc agagctacaa gaattagtcc cagaagcttc tataggtttt gttcatgggc
     5761 aaatgagtga aattcaactt gaaaatacct tgattgactt tataaatggt gattatgatg
     5821 tccttgtggc tacaacaatc atcgaaacag gagttgacat ttctaatgta aacactttgt
     5881 ttattgagaa tgctgatcat atgggattgt caactttata tcaactacga gggcgcgtcg
     5941 gaagaagtaa tcgtattgct tatgcttacc tgatgtatcg tcctgataag gtcctaacag
     6001 aggtttctga aaagcgttta gaggctatta aaggctttac tgaattaggt tcaggcttca
     6061 agattgctat gcgagatttg tctatacgag gagcaggtaa tattttaggg gcttctcaga
     6121 gtggctttat tgattcggtc ggttttgaaa tgtattctca gttattggaa caggctattg
     6181 ctagcaagca gggaaaaacg actgttcgtc aaaaaggcaa tactgaaatc aatcttcaga
     6241 ttgatgccta tttaccagat gattatattg cagatgagcg ccaaaaaatt gacatttaca
     6301 agcgtattcg agaaattcaa tcaagagaag attatctcaa tttgcaagat gagcttatgg
     6361 atcgttttgg agagtatcct gatcaagttg cctatttgtt agagatagct ctgctaaaac
     6421 attatatgga caatgccttt gcggaattag ttgaacgcaa aaataatcag gtcattgttc
     6481 gatttgaagt aacttcttta acttatttct tgactcagga ttatttcgaa gccttatcga
     6541 aaacccatct taaagctaaa attagtgaac atcaggggaa aatcgatatc gtctttgacg
     6601 ttcgccatca aaaagattat agaattttag aagaattgat gttatttgga gaaaggctta
     6661 gtgagataaa aatcagaaaa aacaattcag tttttaaata ataatttgaa acaactttta
     6721 gactgaatag tattaatgac aatggaacga actagctctt tatacttttg tcaaaaatct
     6781 aagatctttg ctgcgaaatt aggatctttt ctaccattta aaaaataaaa atgataaaat
     6841 gaagaggatt gtaggagaaa ttatgagact agataaatat ctaaaggtat cgcgccttat
     6901 taaacgtcgt tcagtagcaa aagaagttgc ggataaggga cgaattaaag ttaatgggat
     6961 acttgctaaa agttcaacga atataaaact aaatgatcac attgaaatta gttttggaaa
     7021 taaattactg acagtaagag tcattgaaat aaaagatagt acaaaaaaag aagatgctct
     7081 taagatgtat gagataatca gtgaaacaag gataacatta aatgaagaag cctagtattg
     7141 ttcaattaaa taatcattat attaagaaag agaatctcaa aaaaaaattt gaagaagaag
     7201 aatctcaaaa aagaaatcgt tttatgggat ggatccttgt aagtatgatg tttttattta
     7261 ttttgccaac ttataatctt gtcaaaagtt atgttgattt tgaaaagcaa aatcaacagg
     7321 tggttaaatt aaaaaaagag tataatgaat tgtcaaagag tacaaaaaaa gaaaaacaat
     7381 tagcagaacg actaaaagat gataattttg tcaaaaaata tgctagggca aaatactatt
     7441 tatcgcgtga aggagaaatg atttatccta ttccaggact attaccaaaa tgatgatgga
     7501 caatattgta aaaaaaatag aagcatttct tgctttttct gataaaaaat tagcagagct
     7561 gcaacaggaa aatcaaaaag ttaaagaaga aagtcagtat attcaaaaaa actagaaagg
     7621 agtcaatatg agaaaattat tagcggctat gttaatgact ttttttctga ctcctttacc
     7681 agtgattagt acagaaaaaa aacttatatt ttcaaaaaat gctgtttatc aattgaaaca
     7741 agatgtcgtt caatcaacac aattctataa tcaaataccc tctaatccaa atctttatca
     7801 agaaacgtgt gcctataaag acagtgattt aactctacca gcaggaagat taggtgtaaa
     7861 tcaaccatta cttattaaat cgcttgtgct taacaaagaa tctttaccgg tttttgagtt
     7921 agctgatggt acctatgttg aggctaatcg acaattgatt tatgacgata ttgtacttaa
     7981 tcaagtagat atagatagct atttttggac acaaaagaaa cttaggcttt attcagcccc
     8041 ttatgtttta ggtacgcaaa caattccttc ttctttttta tttgctcaaa aagttcatgc
     8101 cactcaaatg gcacaaacaa accatggaac ttattatctt attgatgata agggctgggc
     8161 atcacaagaa gatctagttc aatttgataa ccgcatgtta aaagtccagg aaatgctctt
     8221 acaaaaatat aataacccaa attattcaat ttttgtaaag caactcaaca cacaaacaag
     8281 tgctggtatt aatgctgata aaaaaatgta tgctgcaagt atctcgaagt tagcaccact
     8341 ttatattgtt caaaaacaat tacaaaaaaa gaaattagca gagaataaaa ctttgactta
     8401 tactaaagat gttaatcatt tttatggaga ctatgatcca ttgggaagtg gtaaaattag
     8461 taaaatagct gataataaag attatcgtgt tgaagaccta ctgaaagctg tagcacaaca
     8521 atcggataat gtagcaacta atattttagg ttattatcta tgtcatcagt atgataaagc
     8581 tttccgctca gagataaaag ctttatcagg tatcgattgg gatatggagc agcgcttatt
     8641 aacttctcgt tcagctgcaa atatgatgga agctatttat catcaaaaag gccaaattat
     8701 ttcttacctt tcaaataccg aatttgatca acaacgtatc acaaaaaata ttactgttcc
     8761 agttgcacat aaaattggtg atgcttatga ttataaacat gacgttgcta ttgtttacgg
     8821 taatactcca tttattttgt ctatttttac aaataaatca acctatgaag atattacggc
     8881 tattgcagat gacgtttatg gtattttaaa atgatgacct atcaagaaat ttttaatgaa
     8941 ataaaaaata aagcctactt taaaaatcat agacatgtgt taatagccgt atctggtgga
     9001 gtagattcaa tgaatttatt gcacttttta tacctgtttc aagacaaatt gaaaattcgt
     9061 attggtattg ctcatgttaa tcacaaacaa agatcagaat cagattcaga agaagcttat
     9121 ttaaagtgtt gggctaaaaa acatgacata cctatttatg tttctaattt tgaaggaata
     9181 ttttcagaaa aagcagcacg tgattggcgc tatgcttttt ttaagagtat tatgttaaaa
     9241 aataactatt cagctttagt aacagctcac cattcagatg atcaagcaga aactattttg
     9301 atgaggctaa ttagaggaag ccgattgagg cacttgtcgg gtataaaaag cgtgcaacca
     9361 tttgccaatg gtcaacttat aagacctttt ttaactttct caaaaaagga cttgccagaa
     9421 atttttcatt ttgaagattc ttcaaataga gaattatcat ttttaagaaa tagagttaga
     9481 aataattatt taccactgtt aaagcaggaa aatcctaggt tcattcaggg attaaatcaa
     9541 ttagcacttg aaaatagctt actttttcaa gcttttaagg agctaacaaa tcatattact
     9601 accactgatt taacagaatt taatgagcaa tctaagtcaa ttcaatactt tttgttacaa
     9661 gattatttag aaggttttcc agatttagat ttaaaaaaat ctcaatttac tcaattattg
     9721 caaattatcc aaactgctaa acaaggctat tattatc
//
LOCUS       DAUGJR010000051         9290 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUGJR010000051 DAUGJR010000000
VERSION     DAUGJR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9290
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.051"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            143..298
                     /locus_tag="VH800_001554"
     CDS             143..298
                     /locus_tag="VH800_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362608.1"
                     /translation="MDEKNPLEQFEEFCKNNSFEYVKGWVDGMQSVLNILSMELSKKN
                     GSTSEVD"
     gene            complement(279..692)
                     /locus_tag="VH800_001555"
     CDS             complement(279..692)
                     /locus_tag="VH800_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362609.1"
                     /translation="MEKFNFWLTIATAVLPAAISAIISFLASRYKNRSDIESLEKKFN
                     HEMTTIEKNHSNDLERLEKQYQHDFEAMEKNHFRELEKMKEAHTLELENIQKQSEAEV
                     NNTVAQGLMTMLGSAMTPALSKYLEENDVFNQPPK"
     gene            740..955
                     /locus_tag="VH800_001556"
     CDS             740..955
                     /locus_tag="VH800_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8362610.1"
                     /translation="MSQQHKKWSALVEQRLKEKGWTRVDLALAAGLRSSGTITDLLTK
                     GKGSVDLKVRVSKILSIREPWELFENE"
     gene            1017..1292
                     /locus_tag="VH800_001557"
     CDS             1017..1292
                     /locus_tag="VH800_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEQ8362611.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVMKMINNETEIYPLELNKKQVS
                     KMFGVDPKTFDARFNSHKDFPRIETGGREKYPRDLAIEWYHRNWSIT"
     gene            1289..1459
                     /locus_tag="VH800_001558"
     CDS             1289..1459
                     /locus_tag="VH800_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362612.1"
                     /translation="MNKLELFLLATTVILAVIARVQHEVIKKHNSPENKRRIFREVAL
                     ENSKKWSAERYV"
     gene            1452..1655
                     /locus_tag="VH800_001559"
     CDS             1452..1655
                     /locus_tag="VH800_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362613.1"
                     /translation="MSKWELQKQLLANATDFESTVEALFELNELGEISDEELLLNLRS
                     SYRKYSEEKLCIIDKLIKLGGAE"
     gene            1652..2038
                     /locus_tag="VH800_001560"
     CDS             1652..2038
                     /locus_tag="VH800_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362614.1"
                     /translation="MMTTFEKIIKNLNRIERELVKPEAERRDSLPILSAQLSAIKQDL
                     KLMLWIELPALNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            2184..2387
                     /locus_tag="VH800_001561"
     CDS             2184..2387
                     /locus_tag="VH800_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362615.1"
                     /translation="MNYLEYALAYLERELEIIDDEVIEVELPGGDWEFVPNPYYEEGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            2475..2774
                     /locus_tag="VH800_001562"
     CDS             2475..2774
                     /locus_tag="VH800_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362616.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            2774..3928
                     /locus_tag="VH800_001563"
     CDS             2774..3928
                     /locus_tag="VH800_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEQ8362617.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYED
                     AEIELEKRIDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVLTNKEAAATILEKNGFEDIYKPKELLSM
                     GALEKMVGKKRFEDMMAFILDKPQGKPVLVKNSDKRPALNSLEQAIKEFE"
     gene            3932..4330
                     /locus_tag="VH800_001564"
     CDS             3932..4330
                     /locus_tag="VH800_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362618.1"
                     /translation="MKIYKVKVKFRQTCHKKFKGKKYSYFSFEELRVGDLVVVETVYG
                     PSVAKVTEVVDANELFTATSYVISKVDTSLLAGKKELMATALTVKANIDAETAEFAAK
                     YKDAYYLGLFDQYKNQNPELAELLTQLKEL"
     gene            4341..4898
                     /locus_tag="VH800_001565"
     CDS             4341..4898
                     /locus_tag="VH800_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEQ8362619.1"
                     /translation="MTPSTTKVVTGKVRLSYAALLEPKAFEGQEAKYSTVILIPKTDK
                     VTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHMFMSVS
                     SKTRPQIIDRYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAKGD
                     YLGGRSSADADFDEWNEEEDEDDIL"
     gene            4941..6863
                     /locus_tag="VH800_001566"
     CDS             4941..6863
                     /locus_tag="VH800_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEQ8362620.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPAQWQCTMVLA
                     QELGLPASLEKCALYLKLAQEKDAAGKNLIKYFSVPCKPTKANGGRTRNLPEHDPGKW
                     QMFINYCMQDVVVEMAIAEKLESVPVHDREWDYYVCDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKALTGLDNPNSRAQLLPWLKEHGYSANGLTKADVEQELKKAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGYTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKI
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDRAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYDVVFHVHDEAIIEGSGLIIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            6868..9252
                     /locus_tag="VH800_001567"
     CDS             6868..9252
                     /locus_tag="VH800_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8362621.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAFVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLSEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVSDLPEIKDHLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNNFKTKFDPELHARSSHPVVYDPEATCETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGAALKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELNYENKNVKSDGKQAKNWVGFRLKSEF"
BASE COUNT         2995 a         1629 c         2209 g         2457 t
ORIGIN      
        1 tttttgttgg tgtttttact ataccttgat tttagaatat agtttgtaaa atgtcaatac
       61 taaagttgaa aaacttcgcg attattttcg ctttactttt aataaaaaaa ctcccgattg
      121 ggagtagaaa ggagagagta gtatggatga aaaaaatcca ctcgaacagt ttgaagagtt
      181 ttgcaagaat aattcatttg agtatgttaa aggctgggtt gatggcatgc aatcagtttt
      241 aaatattctc tcaatggaat tatctaaaaa aaatggatct acttcggagg ttgattgaat
      301 acatcgtttt cttctaaata tttagagagc gctggtgtca ttgctgagcc taacatggtc
      361 attagtcctt gagcaacagt attgtttact tctgcttctg actgcttttg aatattttct
      421 aactctaaag tgtgagcttc tttcattttc tcaagttctc gaaaatgatt tttttccata
      481 gcttcaaaat catgttgata ctgtttttca agcctttcta ggtcattact atgatttttt
      541 tcgatagtag tcatctcatg attgaacttt ttttctaacg attcaatatc agatctgttc
      601 ttatatcttg aagctaagaa gctaataata gcagaaattg cagctggcaa aacagctgtt
      661 gcaatagtta accagaaatt aaatttttcc ataataaacc tcaacatttt tatttatatt
      721 atatcagaaa ggagagcaga tgagtcaaca acacaaaaaa tggtcagctc tagttgaaca
      781 gcgattaaaa gaaaaaggtt ggacaagagt cgacttggca cttgcggctg gtttgcggag
      841 ttcaggaacg attactgact tacttactaa aggaaaagga agcgttgacc ttaaggttag
      901 ggtttcaaaa attcttagta tccgtgagcc gtgggagttg ttcgaaaatg aatagtacac
      961 aaaaaagcca ctgctggaac agtgacttag ctaaaacata ttaaaggaat tttatcatgg
     1021 atagcagatt attacaaatg ctagatgagt ttgaagcggg ccttattgat cgcaaaatca
     1081 aagtcatgaa aatgattaac aatgagacgg aaatttatcc gctagaactc aataaaaagc
     1141 aagtcagtaa gatgtttggg gttgacccta aaacatttga cgcaagattt aacagccaca
     1201 aagatttccc gcgtattgaa acggggggtc gggaaaaata cccacgagat ttagccatcg
     1261 agtggtatca cagaaattgg agtataacat gaacaaatta gaactatttt tattagcaac
     1321 aaccgtcatc ttagcggtca ttgctagggt gcaacacgaa gtcatcaaaa aacacaattc
     1381 gccagagaat aaacgcagaa tttttaggga agtggcttta gaaaacagca agaaatggag
     1441 tgcagaacgt tatgtctaaa tgggaattac aaaagcaact gttggctaat gcgacagatt
     1501 ttgagagtac agtagaagct ctgtttgagt taaatgaatt gggtgaaatc tcggacgagg
     1561 agctcttgtt aaatttgaga agtagctaca ggaaatactc agaggaaaaa ctttgtatta
     1621 ttgacaaact cattaagctt ggaggcgcag aatgatgaca acttttgaaa agattatcaa
     1681 gaaccttaat cggattgaga gggaattagt taagcccgaa gctgaaagac gagatagctt
     1741 acctatccta tctgctcagt tgagtgctat caagcaagat ttaaaattga tgctttggat
     1801 tgaacttccg gcgttaaata acgtagaaaa atatgaagct ctttatcaag gaaatgattt
     1861 taaattcagt gaaactttct tagagcgtca agcgacgaga aaagcctttt ggagacgatt
     1921 agctaaagaa actttcaaag aagaccagga taagaggaac tttgttaagt tggctgagaa
     1981 agaatttaaa ggtgcaactt tgtcatggca agaatttttg tggggtaaaa agaaatgaac
     2041 atatcactaa aatttattga tgaaacccta gctggtttaa atgatatttt acgccagggg
     2101 gggctctctt gttcccaaag ccaagccctg gcggacgcag tttttatatt aacagcttta
     2161 aaacaagtaa ttgaggagag aaaatgaact atttagaata tgcactagct tatcttgaac
     2221 gtgagctaga aattattgac gacgaagtta tcgaagttga gttgccgggc ggagattggg
     2281 agtttgtgcc taacccctac tacgaggaag gtttacatga tagcccacac tatcgtagtc
     2341 aggttgctaa agacattctt gatattaaag gacttttggg gaggtgaggc tattgattgc
     2401 atcaaaaaag acggcttagg aaaccgtcaa caattataca caattaaatt ataacacaga
     2461 aagagagaaa cacaatgatt gaagtaactt ttaaagcaga gagcatggca ggtgttttcg
     2521 atgctatgcg tgaagctctg gatatgccga agacagtaac caaggatgtt gttgaagaaa
     2581 aaccagctcc taaaaagaaa gaagagtctg taactttgac attagctgat attaagaaaa
     2641 tggctaaagc caaggttgaa gaagggaagt caaaggacat caaggaagtc ttgaaagaga
     2701 tgaacgtcgc aaaagttggt gaacttgaag aataccagtt tgctgagttt gttgagaagt
     2761 tggaggccct ctaatgccag tagaaaatca cgcactactg tctgcttcta gtgctcacag
     2821 atggctttat tgccctatgc tgccgagatt agaagcagac taccctagcc gcgataccgt
     2881 atacactcaa gagggcacaa gcgcccatga gctttctgaa atcaaactga tgtacaagtc
     2941 tggtaaaatc accaagcgta aatttaacac gttaaccaag gcttttaagg aaaactcaga
     3001 cttctacaac gaagagatgg aagagatgac ggaactttac acagatattg ttatggagca
     3061 cctaaatgct tatgaggatg ccgaaattga acttgaaaaa cggattgatt ttagcgactg
     3121 ggtgcctggc ggttttggga cttcggatgt cgtcattttg gcggatgggg tcattgaaat
     3181 tattgatctt aagtatggca agggtatgcc tgtgtctgct aaccaaaacc cgcagatggg
     3241 gttgtacgct ctgggagctt acgcttccta cgatatggtt tatgactttg accgtatcaa
     3301 gatgacaatt attcagccgc gtttagattc ggttagttct gttgacattt acgtagagga
     3361 gcttctgtat tgggcggata atgttgtctt gcctatggcc gctcaagcag acgcaggtat
     3421 tggcgactgg aacctaagtg aaaaagtatt gcagtggtct cctgtcgcag ctaaattggt
     3481 gccaagagcg caagaaaact gggaattaat tgataaatat gactatcagg agcctgtcta
     3541 tttatctgat gaagccgtcg cagagatcct tgacaaagcc tcagctatca agaagtgggt
     3601 tgagtcagtt gaagcctatg ccctgaaaga agcactctca ggaaaagaag ttccaggcta
     3661 taagattgtc gaaggtagaa gtaatcgtgt gcttactaat aaggaggcag ctgcgacaat
     3721 acttgagaaa aacggctttg aagatatcta caaaccaaaa gagctactgt ccatgggggc
     3781 tctagagaag atggtcggta agaagcgttt tgaggacatg atggccttta tccttgataa
     3841 accacaaggt aaacctgtcc ttgtcaaaaa tagcgacaag cgacccgcgt taaatagctt
     3901 agaacaagca ataaaggagt ttgaatagaa tatgaagatt tataaagtaa aagttaagtt
     3961 tagacaaaca tgccataaaa aattcaaggg taagaaatac agctacttta gttttgaaga
     4021 gttgcgggta ggtgaccttg tggttgtcga aactgtttat ggccctagcg tagccaaggt
     4081 aacagaagtt gttgatgcca atgagctttt tacagctacc agctatgtta tttccaaagt
     4141 ggatacttca cttttagcgg gcaagaaaga gttaatggct accgccttga ctgtaaaagc
     4201 aaatattgat gcggaaacgg ctgagtttgc agcgaaatat aaagatgctt attatttagg
     4261 cctgtttgat cagtacaaaa accaaaatcc agaattagca gagttattaa cacaattaaa
     4321 agaattatag gagaagaatt atgacaccaa gcacaactaa agtagtaacc ggaaaagtac
     4381 gcctaagcta tgcagcttta ctagagccta aagcctttga aggtcaagag gctaagtatt
     4441 caacagttat cttaattcca aaaacagaca aagtcacaat caagaaaatt aaagacgcgc
     4501 agaaagctgc ttatgaagct gccaaggaca ataaactcaa aggggttaaa tgggagcgcg
     4561 ttaagacaac gcttcgtgac ggtgacgaag agatggatac tgaagagcac ccagagtacg
     4621 ctggacacat gttcatgtca gtgtcaagca aaactaggcc gcagattatc gaccgttaca
     4681 aaaaccccgt tgactccgca gacgaagttt actcaggagt atacgcacga gtatcattaa
     4741 atgcctatgc ctacaatact gcgggtaaca agggtatctc ttgtggtctg aataacgttc
     4801 agattgttgc taaaggagac taccttggcg gtcgttcgtc agctgatgca gactttgacg
     4861 agtggaacga agaagaggac gaagacgaca ttttatagta gagggcctct ttagaggctc
     4921 ctcattttta aaggagaggt atgagacatt taaatattga tattgaaacc tatagttcga
     4981 atgacatcaa aaatggggtt tacaagtacg ctgacgctga agattttgag attttacttt
     5041 tcgcttactc tatagatggc ggagaagtag agtgccttga tttgacaagg cagtctctac
     5101 ctgaagacat caaagatatg ttatttgatg ataaagtccg aaagcacgcc tttaatgccc
     5161 aattcgaaag agtttgtctc agtcgttacc tcggcctacc ttactattta gatcccgcac
     5221 aatggcagtg tacgatggta cttgcacaag agctgggtct gcctgcaagc ctggaaaaat
     5281 gtgcgctgta tttaaaatta gcgcaagaaa aagacgcagc aggtaaaaat ctcattaaat
     5341 atttttcggt accctgcaag cctacaaaag ccaacggggg aagaacgagg aacctgcccg
     5401 agcatgatcc tggaaaatgg caaatgttta ttaactactg tatgcaagac gttgttgttg
     5461 agatggcaat tgccgaaaaa ctagagtcag ttcctgtgca cgaccgtgag tgggattact
     5521 acgtctgcga ccagagaatc aacgacagag gcgtggcact tgataaagag ttagttgctt
     5581 cggctttgta ttgtaaagat gttaagatgg aaagtttgtc tggtgaacta aaggctctaa
     5641 caggacttga taatcctaat agcagggcgc agctgctacc gtggctaaaa gaacacggtt
     5701 attcggctaa tgggctgact aaagctgatg ttgaacagga acttaagaag gccgaaggag
     5761 agcttaagag agttttagaa cttaaactac aaaccgcgat gtcaagtcta aaaaaatatg
     5821 aagctatgga aagagctatg tgctcagacg gacgagttca tgggctactt cagttttacg
     5881 gggctagccg gacaggaaga tgggcgggca gagttgtcca agtacagaac ttagctagga
     5941 attatataaa ggatctagat gatgctagag agtatgttaa aaagcgtgat attgatgctg
     6001 tggagatttt atacgatagc cttaacgaca ctttaaagca gctcgtgcga acggcactcg
     6061 tggctaaaga tggctatacc ttctatgtct ctgacttctc ggcgattgag gctagggtga
     6121 ttgcatggtt tgctggagag cagtggaggc ttgacgtgtt ttctacgcac gggaaaatct
     6181 acgaggcgtc tgccagtcag atgttcggaa ttccaattga ggagattgac aaggaactac
     6241 gccaaaaggg caaaatttca gagttagcac ttggctatca aggaggtcct ggagcgctta
     6301 agcagatggg ggctctaaat atgggagtca aggaagagga gcttcaaggg ttagttgatg
     6361 actggcgcag ggccaataag aaaatcgtcc aattttggaa agacgtacaa agagccgcca
     6421 tcaaagccat caaatcgaga gcaccgataa aacttggaaa aatacgattt agataccgga
     6481 aaggtttcct ctttataaca ttgcctagcg gtaggaactt agcttatgca agagccaagg
     6541 ttgagccagg cgactatgga gacaaaatca tctatgaggg ccaaggagat agggcctatt
     6601 tcacagcgca agagacgtac ggcggtaagc ttgtcgaaaa tatcgttcag gcgacggcca
     6661 gggatattct agctgaagcg cttctgagga ttgaagctgc aggctatgat gttgttttcc
     6721 acgttcatga tgaggctatt atcgaaggtt caggcctgat aatcgaagag gttaatgatt
     6781 tgatggctca ggctcctgaa tgggcggagg gtcttccttt aaatagcgaa ggctatgtaa
     6841 caaagtatta tatgaaggat tagatagatg aagcaagaaa aactaatagt aaagtcttct
     6901 cccctgcaag agcttcatat cgcaacaggt agttcgcgaa cagctaagac atggaaaaat
     6961 atcacgctaa cttggcagga gctggttgag aggttagaga aacctacagt cacccaagag
     7021 acgtttgcgg agtaccagaa gatgtctcga gcagaaaaag ggcaagcaaa agacgtaggg
     7081 ggctttgtcg gtggatggct aaagcaaggt aaacggaaaa atgaaaacgt tcaaagtagg
     7141 tccttggttg cgcttgacgc agatagccca agtaaagatt tcttagatag gctagacctg
     7201 cttgcagatt atgcattcgt actctacagt actcacagcc actcaaaaaa agctgctaag
     7261 taccgtctta ttatccctac tgaccgttta atgatgcctg atgaatatga gccagtcgct
     7321 agatatttgg ctaaccaact aggcatgtca aactttgatg acacgactta tcaaagcgta
     7381 cgcttgatgt tctggccgag ccactcaaga gatgccgact ttacgtttaa atataacgac
     7441 gaggcttttc tgagtgttga tgaggtgctt gacacatacc cggactggca tgactcaagc
     7501 ttctggccag aaagcccgac gcacgctgtt aaaagacagc gtgaagctaa aaaacaaggt
     7561 gacccgctta gtaaaaaagg acttattgga gccttttgtc gtaactatga cattagacag
     7621 gccattgcaa cattcttatc tgaggtttat gaagaaggaa cgactcctga taggtacacc
     7681 tacactgatg gctcaaccgc aaacggctta gttatctatg atgatgtctt cgcttatagc
     7741 catcacggga cagatcccgt gggggatacg cttgtaaatg cctatgacct tgttcgtatc
     7801 cataaattcg gagagcaaga tagcgaggct aaagataata ctcctactaa taagttgccg
     7861 tcaagtaaag cgatgaatgc ttttgtctct gacttacccg aaattaaaga ccatttaatg
     7921 gcggaggctt taggcgattt cgatgaagag ttaccagtcg aagatgacag aagctggctt
     7981 gaaattgatg agaggggcga accggaggtc aatagttatt tgctagcaac gcagattatt
     8041 aaggaggttc cgatttattg ggatggctta gaatttttac gctacgacgc taaaaaaggc
     8101 atctggttgc caaacgctga ggaatatttg aagagttata tctcaactaa gaaactcggt
     8161 aaaattacta agattaggca cattagcgaa accgtcgtag cgattaaagc acaggctttt
     8221 tcaagtgaag tgtttaccga gagtgatctt aacaagatag tgctagcgaa tggagtctat
     8281 gacctgaggg ataacaactt taagactaag tttgatccag aattgcatgc caggtcaagc
     8341 catcccgttg tctatgaccc cgaggcgacc tgtgaaacct ttgagggttt tcttagagag
     8401 accgtcggag ctgaaaatat agatttcatc tttgagtggt ttggctataa cttttatcgt
     8461 gaatacacta ttcaaaaaat gctattcatc tatggtagcg ggggcactgg caaatcaaca
     8521 ctaattaata ttttacgtga aatgataggc gctgataatt attcagccgt gacactgcag
     8581 tacctgatgc aagaacgctt tgcaaaaatc ggcttatatc gtaagacagc taacttcgat
     8641 accgatgcta aacctcaata cttagcagat ggcgcagcac ttaaaatgtt gacgggggag
     8701 gatactattc acgcagaccg taagaataaa gagccgatta acttttacaa ttatgctaag
     8761 ctgtcttttg ccatgaatga gctcccacct atgcgagatt tcagcggagg acttaaacgc
     8821 cgcatgatga tcctcgagat ggataaggtt ttaacgcagg aagttaaggc gaaatacccg
     8881 ctagataaga ttatgagcga ggtgcctggt atctttaaca gagcgatgga ggggcttaga
     8941 aaggccttaa gtaagagaga tttcagtatt agtgccagca tgaggtcaag tgtcgagaaa
     9001 tgggaaaaag gcaacgatgt cgtagctatg ttccttgaag acgagtgtga acttggcgaa
     9061 gacttcaaag ttcctgttag ggatgtctac ccagcttata aattctattg tcaggattca
     9121 ggctacaaac ctttggcaaa aaatgcattt aaccatcggc taagagagct aaattatgaa
     9181 aataaaaacg ttaaatctga tggaaagcaa gccaaaaatt gggtcggctt taggttaaaa
     9241 agtgagtttt aggggttact tttttggaat tagagtttgg taaccctaga
//
LOCUS       DAUGJR010000052         9175 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUGJR010000052 DAUGJR010000000
VERSION     DAUGJR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9175
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.052"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            200..523
                     /locus_tag="VH800_001568"
     CDS             200..523
                     /locus_tag="VH800_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362622.1"
                     /translation="MQFLQKWFKHSKKEKLKESSSLSTEIEPSENWAKIPAYIPADKS
                     DYKKVTLITSVIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
     gene            580..975
                     /locus_tag="VH800_001569"
     CDS             580..975
                     /locus_tag="VH800_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ8362623.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            1020..2141
                     /locus_tag="VH800_001570"
     CDS             1020..2141
                     /locus_tag="VH800_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8362624.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            2329..2637
                     /gene="citD"
                     /locus_tag="VH800_001571"
     CDS             2329..2637
                     /gene="citD"
                     /locus_tag="VH800_001571"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEQ8362625.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
                     "
     gene            2625..3512
                     /gene="citE"
                     /locus_tag="VH800_001572"
     CDS             2625..3512
                     /gene="citE"
                     /locus_tag="VH800_001572"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEQ8362626.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDII
                     DVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            3515..5047
                     /gene="citF"
                     /locus_tag="VH800_001573"
     CDS             3515..5047
                     /gene="citF"
                     /locus_tag="VH800_001573"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEQ8362627.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEELVEKILDVQDFDHP
                     SAVSLGKHAEHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVIVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            5040..5618
                     /gene="citX"
                     /locus_tag="VH800_001574"
     CDS             5040..5618
                     /gene="citX"
                     /locus_tag="VH800_001574"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEQ8362628.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            5633..7027
                     /locus_tag="VH800_001575"
     CDS             5633..7027
                     /locus_tag="VH800_001575"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEQ8362629.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLTDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVITCRPADLIEPQMIYLRDEIAPYAHSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(7137..8189)
                     /gene="citC"
                     /locus_tag="VH800_001576"
     CDS             complement(7137..8189)
                     /gene="citC"
                     /locus_tag="VH800_001576"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEQ8362630.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(8278..8760)
                     /locus_tag="VH800_001577"
     CDS             complement(8278..8760)
                     /locus_tag="VH800_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEQ8362631.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTINDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
BASE COUNT         2771 a         1825 c         1866 g         2713 t
ORIGIN      
        1 cttttcttgc tatcagtatc ttgatctcag tttttcaaca gttacctaaa aataaaataa
       61 aaggtaactg ttgaaaaact ttatgaaaca ttgaaagcgc tcttagaaag aacacaaaaa
      121 agccatctca aaaaagattg gtagtatata ataaacttac tagttcctta aataggtaaa
      181 tgtgaaaaag aggtagctca tgcagttttt acaaaaatgg tttaaacact ctaaaaaaga
      241 gaagttgaaa gaatcctcgt cccttagtac agaaatagaa ccttctgaaa actgggcaaa
      301 gattcccgct tatattcctg cagacaaaag tgattacaaa aaggttactt taattaccag
      361 tgttattgct gctggcgata gacctaatag tcaattcaag gttaaacgca ttctcaagcg
      421 caatcctgag gcaatcactg tttctttaat tgcttcaagt atcgctgcag gtgtttaccc
      481 agaaagtcag tttcgggtga catccatcta ttgcaaaagg tagtcggtga acgatacttt
      541 agacgaactc atgacacaat aacatatagg agaaaaatga tgttacgaaa atttaaaatt
      601 accattgacg gtaaagagta tcttgtagaa atggaagaaa tcggtgctcc tgcccaagca
      661 gctgcccccg ctcaaccaat atccactcca gtacctgtcc ctactgaagc aagcccacaa
      721 gtggaggaag cgcaagcacc acagccagta gctgcagcgg gagcggatgc cattccatca
      781 ccaatgcctg gaaccatctt aaaagtctta gtagcagtgg gagaccaagt aactgaaaat
      841 cagccactat tgattttaga agccatgaag atggaaaatg agattgtggc ctcatcagca
      901 ggaaccatta cagctatcca cgtcggtcca ggtcaagtgg tcaatcctgg tgatggtctc
      961 attacaattg gttaatagta ctataactag aataaataga cagaaaagga agtgaatttg
     1021 tggacacttt aatcgcagga ataacctcca tcaccattcc tcaaattgtt atgatggtca
     1081 ttggtgccct cttaatgtat ctaggaatta aaaaagaata cgaaccaacc ttacttgtcc
     1141 ccatgggact tggaaccatt ctcgttaact tccctggttc aggagtttta acacaagtgg
     1201 ttaacggagt cgagcaagaa ggggtttttg aggctctctt caattttggg attggaacag
     1261 aacttttccc actgttgatt ttcattggta taggagccat gattgacttt ggccccttgc
     1321 ttcaaaaccc attcatgctc ttgtttggtg ctgcagctca attcggaatt ttctttgttg
     1381 tggttgttgc cgtactggct ggctttgaca ttaaagaagc agcttcaatc ggcattatcg
     1441 gagcagcaga cggaccgact tctatctttg ttgccaacca actggccaag gatttactgg
     1501 gtccaattac ggttgcagcc tattcttaca tggctctggt tcctattatc caaccatttg
     1561 ccattaaatt agtgacaacg aaaaaagagc gccgtatccg tatgacttac aaagctgaga
     1621 atgtatctca aatgactaaa atcttattcc caatcatcat taccttagta gcagggttca
     1681 tcgccccaat ttctctacct ttagttggct ttttgatgtt cggtaactta ttacgggagt
     1741 gtggtgtgct cgatcgcctg tcacaaactg ctcaaaatga attggtaaac attattagta
     1801 tcttgcttgg attgaccatc tctattaaaa tgcaggcaga cctgttctta aatgtacaga
     1861 cactcttaat catcgtcttt ggtttacttg cttttatcat ggattctatc ggtggggtca
     1921 tgtttgccaa atttctcaat ctcttccgaa aagagaagat taatccaatg attggcgctg
     1981 cgggtatttc agcttttcca atgtcaagtc gtgtcattca aaaaatggca acagatgaag
     2041 acccgcaaaa ctttatcctc atgtatgctg taggtgccaa tgtctctggc caaatcgcct
     2101 ctgttatcgc aggtggtttg ttgctagctt actttagcta agaaaggaag gaaaccttat
     2161 gacaattaat atggaccatt tgattagttc ctttgagcta atggcgcttg gtatggcagg
     2221 tgtctttatc gtgttaggca ttctctatct tgtcgcagag atcctgatca aacttttccc
     2281 agttagtaaa taacaatatc atttaagaaa atcaaggagg taaacgcaat ggatattaaa
     2341 caaactgccg ttgctggttc acttgaatca agtgacctaa tgattacagt atcccctaat
     2401 gacgagcaaa ccattacaat aaccctagac agtagtgttg aaaaacaatt tggcaatcac
     2461 attcgtcaac tcattcatca aaccctagtg aatttgaagg tgacggctgc taaagtagag
     2521 gctgttgata aaggtgcatt agattgcacc attcaagcga gaaccatcgc agctgttcat
     2581 cgcgctgctg gtattgacca atacgattgg aaggagattg actcatggaa cgtttaagaa
     2641 gaacaatgat gtttgtgcct ggtgccaatg cagccatgct tcgagatgct cctttatttg
     2701 gcgctgattc aatcatgttt gacttggaag attctgtttc actcaaagaa aaagacacct
     2761 ctagagctct cgttcatttt gcgcttaaaa cttttgatta ttcaagcgtt gaaacggttg
     2821 ttcgtgtgaa tggtcttgat tcttgtgggg ctttagacat cgaagctgtt gttttggcag
     2881 gtgtcaacgt gattcgtctt ccaaaaacag agactgctca agatattatt gatgtggagg
     2941 ctgttattga acgtgtcgaa cgcgagaaca gcattgaagt tggtcgcaca cgtatgatgg
     3001 cagccattga atcagccgaa ggtgtcctaa atgctcgtga gattgccaaa gcttctaagc
     3061 gcttgattgg tattgctctt ggagcagaag actatgtcac gaatatgaaa acgcgtcgtt
     3121 acccagatgg tcaagaatta ttctttgctc gtagcatgat tttacacgct gctcgtgctg
     3181 ctggaattgc tgccattgat actgtttatt ctgatgtcaa taataccgaa gggttccaaa
     3241 acgaagttcg catgatcaaa cagttaggat ttgatggtaa atcggtcatc aaccctcgcc
     3301 aaattcctct ggtcaatgag atttataccc caacaaaaaa agaaattgac catgccaaac
     3361 aagtcatctg ggcaattcgt gaagctgaaa gcaaaggctc tggcgttatt tccttaaatg
     3421 gaaaaatggt tgataaacca atcgttgaac gtgcagaacg tgtgattgcc ctagcaacag
     3481 cagcaggtgt tttatctgag gaggatattt aaagatggta acaaataaac tcggtagaga
     3541 tattcctcaa ccatacgccg accaatacgg tgtctttgaa ggagaactcg caaatatcaa
     3601 acagtatgac gaatcaagtc gccgtattaa accagttaag cctggagatt ctaaattact
     3661 aggatctgtt cgtgaagcga ttgaaaaaac aggtttaaca gatggcatga ccatttcttt
     3721 ccaccaccat ttccgtgaag gggatttcat tatgaatatg gtcttggagg aaattgccaa
     3781 aatgggcatt aaaaacctgt ctattgcccc aagttccatc gctaatgtac atgagccttt
     3841 gattgatcac atcaaaaatg gtgtggtcac taacatcact tcatctggtc ttcgtgacaa
     3901 agtaggggca gccatctcag aaggactaat ggaaaatcct gtggttattc gctcccatgg
     3961 tggtcgcgct cgtgccattg ctagtgggga tatccatatt gatgttgcct ttctgggcgc
     4021 cccaagttca gatgcttacg gaaatgttaa tgggacaaaa gggaaagcaa cctgtggttc
     4081 tttgggctat gccatgattg atgccaaata tgcggatcag gtggttatct tgacagataa
     4141 tttggttcct tatcctaata ccccaatcag cattcctcaa acagatgttg actatgtggt
     4201 aacagtggat gctatcggag atcctcaagg aatcgccaaa ggggcaactc gttttacgaa
     4261 aaatcctaaa gaactcttaa ttgcagaata cgccgctaaa gtaatcacca actctcctta
     4321 ttttaaagaa ggattctctt tccaaactgg aacaggtggc gcttctttgg cagtaacccg
     4381 tttcatgcgt gaagctatga ttaaagaaaa tatcaaagct agctttgctc ttggtggtat
     4441 taccaatgct atggtggagt tgctcgaaga agaactggtt gaaaaaattc ttgatgtcca
     4501 agactttgat cacccatcag ctgtttctct tggtaagcat gctgaacatt atgaaattga
     4561 tgccaacatg tatgcctcac ctttgagcaa gggtgctgtt atcaatcaat tagacacttg
     4621 tattttatca gcccttgaag ttgatactaa cttcaatgtt aatgtgatga caggatctga
     4681 cggcgtgatt cgtggcgctt ctggaggaca ctgcgacact gcctttgcgg ctaagatgag
     4741 tttggttatt tcaccactta tccgcggacg catcccaact tttgtagatg aggttaatac
     4801 ggtcattaca ccaggaacaa gtgtcgatgt gatcgtcaca gaagtgggaa ttgccattaa
     4861 cccaaatcgt caagacttag tagaccattt caaatccctc aatgtgccac aatttagtat
     4921 tgaggagcta aaagagaagg cttacgccat cgttggcaca cctgagcgta ttcaatatgg
     4981 tgataaggtt gttgctctta ttgaataccg tgacggtagc ctcatggatg tggtttacaa
     5041 tgtgtaaaga cacttatttt tcaggcgaag ctatccaact tagtgatatg ttaagagccc
     5101 gcgaagaaag agctctgcgt cagctgcatt tattaaagga gtacccagaa ggtagcttat
     5161 tatcggtcac catgaatatc cctggaccaa ttaaaacctc tcctaaactt cttgaagctt
     5221 ttgatatagt gattaaggcc attcaaactg ccttagctga cgataagatt tgttaccagt
     5281 tgcgattact gcctacaacg ggttatgagt attacctcat cacaagtcta cctagccgcg
     5341 acctgaagtt aaaaatgata gccttagaga cagagttgcc aataggtcgt ctcatggatt
     5401 tagatgtctt ggtcttgcaa aatgatctgc ctcattcaat tagcagaacc gtattaggag
     5461 gctcccctag gcaatgtttt atctgttcta aagaggccaa agtctgcggt cgcctacgta
     5521 agcacagtgt cgaggagatg cagactgcta tttcaaaatt actccattca tttttcaata
     5581 aagacaacca atcatcgtca tcagataaga caggttgatg aggagaacaa ttatgacgaa
     5641 aatccgtata acggaaacag ttttacgtga tggtcaacaa agtcagattg ccacacgtat
     5701 gacaaccaag gaaatgattc ctattctcga aacgctagac aatgctggtt atcatgccct
     5761 tgaaatgtgg ggaggagcaa cctttgattc ctgcctacgc tttttaaatg aagacccttg
     5821 ggaacggcta agagccatcc gtaaagcagt gaaaaagact aaacttcaga tgctcttacg
     5881 cggacaaaac cttcttggat atcgcaatta tgctgacgat gtggtcagat cctttattca
     5941 aaaatccatt gaaaatggga ttgatattgt ccgtattttc gatgctttaa acgacccacg
     6001 caacttgcaa acagctgttt cagcgactaa aaaatttgga gggcatgctc aagttgccat
     6061 ttcttacacg acaagtccgg tacataccat tgactacttt gttgaattgg cgaaagctta
     6121 ccaagctatc ggagcggact ccatttgtat caaagacatg gctggtgtct taactcctga
     6181 aataggttac caattggtca aatgtatcaa ggagaataca actatccctc ttgaggttca
     6241 tacccatgct accagtggta tttcagaaat gacttactta aaagtagcag aagcaggagc
     6301 tgatattatt gatacggcga tttcctcttt ttcaggggga accagtcagc ctgccacaga
     6361 gtcaatggcg attgccttga cggatttagg ctttgacaca ggcttggata tgcaagaggt
     6421 ggccaaagtt gcagaatatt tcaacactat tcgtgaccac tatcgagaaa tagggatttt
     6481 aaatcctaaa gtcaaagata ctgagccaaa aacattgatt taccaagttc caggtggcat
     6541 gctatcaaac ctattgagcc aattaaccga gcaaggccta actgataaat acgaagaagt
     6601 cttagcagaa gtacctaaag taagggctga tcttgggtat ccgccactcg taacgccatt
     6661 atcacaaatg gttggcacac aggccttgat gaatatcatc tcaggggaac gttacaaggt
     6721 agttccaaat gaaatcaaag actatgttcg agggctatac ggtcaatcac cagcgccatt
     6781 agcagaaggt atcaaagaga aaatcattgg tgacgaagca gttattactt gcagaccagc
     6841 cgacctaatc gagcctcaaa tgatttatct acgtgacgag attgctccat acgctcattc
     6901 agaagaagac gtgttaagct atgcaagctt cccgcaacaa gctagagatt tcttgggacg
     6961 ccgtgaagat cctttctatg atgttccggt tcaagaagtt actgtacaac tggacattca
     7021 agactaacag agaatgacta atcctcttaa ccattaatct ccttggtgaa acgcatttgc
     7081 tgtaagaaca ataccaaaaa cctacctgat tttgataatc agataggttt tttatcttag
     7141 taatgtttga cagatgaagt ggcttgtatc tttttaataa tgggttgggc ttctagcgaa
     7201 caaaaataat ctaaagacgt tttgggaagg agttttgcca gaaggtccca atcattatct
     7261 ttcaatgcct gcctagccgt tgaggcactg ataggatctt gctgctgatt gatagctttc
     7321 cttggcaaaa tatctaggag gataccagct tgctgcaact gctctgccat aatttcattg
     7381 taaatagcag ttactcggct ggttggctct tctccaacgt atctttttgt aatctgtaag
     7441 gtttgagcaa tctttagaaa aatagcagta tccagcaaag cttggctctt aatcacgtca
     7501 ttgtcttctt tttggaaata ggctgggaaa gtcgcttggc taatcaaata aggacctgtt
     7561 tcatgatata tgacattatc aagatgagct agaccttctt gaatcaacct ctttctcacc
     7621 gaaaaaggaa ttagactgcg gtcttcactg accataaaca gatgaaccca atcattttct
     7681 cttgcagctt tctctactaa aaattgatgc cctaaggtaa aggggttagc gttgataaca
     7741 atagcagcga ctttaccagg tgtttgctca ggcttattaa gtgtcatcag ataatcttga
     7801 aaaccagttt ttttattttc caagaaactg atgtgattgt cgatatggac aatttcagta
     7861 aaaccaagat ctttgaaaaa agcagcagaa gaggtcttcg tataaacaaa aagatgatag
     7921 ttgccaaggg catattcttc atcaatgaga tgactcacaa tcctattaag aagtccttca
     7981 ccttgatagg cactggatac gcaaagacag cgcaagctat ttccaaagta agaaccggta
     8041 gcaatcacat cattttgcgc attcatgatg gcacaagtat aatctaaatg agcatccaaa
     8101 cgaatacctt cttgatgaag caggttcttt acactagcca ttgtcgtttt atctgaagga
     8161 aagacttttg aaatagtgta gtaaggcatt tcttctcctt atctttaatt ttattgaatc
     8221 ataacataac ttagtaccaa aacaggctga tctatctaaa ggcaactctg ttttttatca
     8281 acgccatttt ttaaaaggaa atcgaatgtg tttgacagac tcaaaagtat cagcgatttt
     8341 ttgattgcgt tccacagtcc gcaagttttc ttggtctaat aagtcttgac ttttttccaa
     8401 aacatcaaca gtaatgtagt agagtttgat caggcttcct atcttatatt taccagattt
     8461 tggagacata gcaaccactt cattgagatt actatgaagc cattttttat gaggcttagc
     8521 aggtatagtg gctactacaa agccaagttg ttccaaatga gcttgtgcct gatcaacagg
     8581 aagattaatc acatcattta tcgtgcgtaa ttgcatctct ttttcatgtt tttgttccat
     8641 acgtttttcg ataattggtc gactgttatc aatcgttttt ccaataattt cagtagtgtc
     8701 aggaacaatt gacatcagtt tcccaactac tcctagagct tttcttattc tctttggcat
     8761 cttttatctc ctcaagtcgt ttctttttat tataacaaaa tgtctaaaaa tagtatgcga
     8821 taaaccttgt tctaaaaggt taaatagatc aattcaagga aaaaatagga ggggatccga
     8881 caaaaaaaca caaagattct aaaaaagtca agctatttta gtttagcctt tgtcaatcgt
     8941 atcagttcaa atagaaaata caagttttga caagaattta tttatgtaac aaactgtgtt
     9001 tttgattctt tagtctatct aacgataatg ttatctgatt cttgttttca accaattgat
     9061 gttaaagaag ctgtcttcat gattctctaa tattccttca attttagctt tatattactc
     9121 taagttatca gtaatgacat taagtagttt aacaagaata atcctaaaag ctact
//
LOCUS       DAUGJR010000053         8927 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUGJR010000053 DAUGJR010000000
VERSION     DAUGJR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8927
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.053"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            90..1010
                     /gene="lmb"
                     /locus_tag="VH800_001578"
     CDS             90..1010
                     /gene="lmb"
                     /locus_tag="VH800_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEQ8362632.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1023..3500
                     /locus_tag="VH800_001579"
     CDS             1023..3500
                     /locus_tag="VH800_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEQ8362633.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTP
                     NPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEED
                     GLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDDDSGSDH
                     SKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHF
                     HYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGK
                     VGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSS
                     LPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDIWSKPG
                     HEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKE
                     TFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQ
                     ADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIF
                     QPEGVQFYNKNGELVTYDIKTLQQINP"
     gene            3669..3869
                     /locus_tag="VH800_001580"
     CDS             3669..3869
                     /locus_tag="VH800_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8362634.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(3950..4576)
                     /locus_tag="VH800_001581"
     CDS             complement(3950..4576)
                     /locus_tag="VH800_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362635.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4560..5363)
                     /locus_tag="VH800_001582"
     CDS             complement(4560..5363)
                     /locus_tag="VH800_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362636.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5375..6196)
                     /locus_tag="VH800_001583"
     CDS             complement(5375..6196)
                     /locus_tag="VH800_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362637.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6193..7170)
                     /locus_tag="VH800_001584"
     CDS             complement(6193..7170)
                     /locus_tag="VH800_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362638.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            complement(7283..8911)
                     /locus_tag="VH800_001585"
     CDS             complement(7283..8911)
                     /locus_tag="VH800_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8362639.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         2919 a         1760 c         1776 g         2472 t
ORIGIN      
        1 aaaagatggt agttgccatt gacaaagcat tgataaagga gtaaaattaa ctggttaata
       61 actggttaaa ttataattga ggaggtacta tgaaaaaagg tttttttctc atggctatgg
      121 tcgtgagttt agtaatgata gcagggtgtg ataagtcagc aaaccccaaa cagcctacgc
      181 aaggcatgtc agttgtaacc agcttttacc caatgtatgc gatgacaaaa gaagtatctg
      241 gagacctcaa tgatgtgagg atgatccaat caggtgcagg cattcattcc tttgaaccgt
      301 ctgtaaatga tgtggcagct atttatgacg cggatttgtt tgtttaccat tcacatacct
      361 tagaagcttg ggcaagggat ctagacccta atttaaaaaa atcaaaggtt gatgtgtttg
      421 aagcgtcaaa acctttgaca ctagatagag tcaaagggct agaagatatg gaagtcacac
      481 aaggcattga tcctgcgaca ctttatgacc cacatacctg gacagatccc gttttagctg
      541 gtgaggaagc tgttaatatc gctaaagagc taggacgttt ggatcctaaa cacaaagaca
      601 gttacactaa aaatgctaag gctttcaaaa aagaagcaga gcaactaact gaagaataca
      661 ctcaaaaatt taaaaaggtg cgctcaaaaa cattcgtgac gcagcacacg gcattttctt
      721 atctggctaa acgattcggc ttgaaacaac ttggtatctc gggcatttcc ccagagcaag
      781 agccctctcc tcgccaattg aaagaaattc aagactttgt taaagaatac aacgtcaaga
      841 ctatttttgc agaagacaat gtcaatccca aaattgctca tgctattgcg aaatcaacag
      901 gagctaaagt aaagacatta agtccacttg aagctgctcc aagcggaaac aagacatatc
      961 tagaaaatct tagagcaaat ttggaagtgc tctatcaaca gttgaagtaa aggagattat
     1021 tagtgaagaa aacatatggt tatatcggct cagttgctgc tattttacta gctactcata
     1081 ttggaagtta ccaacttggt aagcatcata tgggttcagc aacaaaggac aatcaaattg
     1141 cctatattga tgatagcaaa ggtaaggcaa aagcccctaa aacaaacaaa acgatggatc
     1201 aaatcagtgc tgaagaaggc atctctgctg aacagatcgt agtcaaaatt actgaccaag
     1261 gctatgtgac ctcacatggt gaccattatc atttttacaa tgggaaagtt ccttatgatg
     1321 cgattattag tgaagagttg ttgatgacgg atcctaatta ccgttttaaa caatcagacg
     1381 ttatcaatga aatcttagac ggttacgtta ttaaagtcaa tggcaactat tatgtttacc
     1441 tcaagccagg tagcaagcgc aaaaacattc gaaccaaaca acaaattgct gagcaagtag
     1501 ccaaaggaac taaagaagct aaagaaaaag gtttagctca agtggcccat ctcagtaaag
     1561 aagaagttgc ggcagtcaat gaagcaaaaa gacaaggacg ctatactaca gacgatggct
     1621 atatttttag tccgacagat atcattgatg atttaggaga tgcttattta gtacctcatg
     1681 gtaatcacta tcattatatt cctaaaaagg atttgtctcc aagtgagcta gctgctgcac
     1741 aagcctactg gagtcaaaaa caaggtcgag gtgctagacc gtctgattac cgcccgacac
     1801 cagccccagc cccaggtcgt aggaaagccc caattcctga tgtgacgcct aaccctggac
     1861 aaggtcatca gccagataac ggtggctatc atccagcgcc tcctaggcca aatgatgcgt
     1921 cacaaaacaa acaccaaaga gatgagttta aaggaaaaac ctttaaggaa cttttagatc
     1981 aactacaccg tcttgatttg aaataccgtc atgtggaaga agatgggttg atttttgaac
     2041 cgactcaagt gatcaaatca aacgcttttg ggtatgtggt gcctcatgga gatcattatc
     2101 atattatccc aagaagtcag ttatcacctc ttgaaatgga attagcagat cgatacttag
     2161 ccggccaaac tgaggacgat gactcaggtt cagatcactc aaaaccatca gataaagaag
     2221 tgacacatac ctttcttggt catcgcatca aagcttacgg aaaaggctta gatggtaaac
     2281 catatgatac gagtgatgct tatgttttta gtaaagaatc cattcattca gtggataaat
     2341 caggagttac agctaaacac ggagatcatt tccactatat aggatttgga gaacttgaac
     2401 aatatgagtt ggatgaggtc gctaactggg tgaaagcaaa aggtcaagct gatgagcttg
     2461 ctgctgcttt ggatcaggaa caaggcaaag aaaaaccact ctttgacact aaaaaagtga
     2521 gtcgcaaagt aacaaaagat ggtaaagtgg gctatatgat gccaaaagat ggcaaggact
     2581 atttctatgc tcgtgatcaa cttgatttga ctcagattgc ctttgccgaa caagaactaa
     2641 tgcttaaaga taagaaacat taccgttatg acattgttga cacaggtatt gagccacgac
     2701 ttgctgtaga tgtgtcaagt ctgccgatgc atgctggtaa tgctacttac gatactggaa
     2761 gttcgtttgt tatccctcat attgatcata tccatgtcgt tccgtattca tggttgacgc
     2821 gcgatcagat tgcaacaatc aagtatgtga tgcaacaccc cgaagttcgt ccggatatat
     2881 ggtctaagcc agggcatgaa gagtcaggtt cggtcattcc aaatgttacg cctcttgata
     2941 aacgtgctgg tatgccaaac tggcaaatta tccattctgc tgaagaagtt caaaaagccc
     3001 tagcagaagg tcgttttgca acaccagacg gctatatttt cgatccacga gatgttttgg
     3061 ccaaagaaac ttttgtatgg aaagatggct cctttagcat cccaagagca gatggcagtt
     3121 cattgagaac cattaataaa tctgatctat cccaagctga gtggcaacaa gctcaagagt
     3181 tattggcaaa gaaaaacgct ggtgatgcta ctgatacgga taaacccaaa gaaaagcaac
     3241 aggcagataa gagcaatgaa aaccaacagc caagtgaagc cagtaaagaa gaagaaaaag
     3301 aatcagatga ctttatagac agtttaccag actatggtct agatagagca accctagaag
     3361 atcatatcaa tcaattagca caaaaagcta atatcgatcc taagtatctc attttccaac
     3421 cagaaggtgt ccaattttat aataaaaatg gtgaattggt aacttatgat atcaagacac
     3481 ttcaacaaat aaacccttaa ccaaaagaag atctcattgt taaagcactg ctttgtcaaa
     3541 gcaagttacg gtgattttga agtcatttta tgtaacgagt agtgataaaa gttggataat
     3601 agcggttttc ttttgcaaag aaatggtatc catgttagaa tgataaaaaa aagaggagga
     3661 ttctaatcat gtcagaagaa aaattaaaat caaaaattga gcaagcatct ggtggcctaa
     3721 aagaaggtgc tggtaagttg acaggtgata aagagctaga agcaaaagga tttgttgaaa
     3781 aaacaattgc taaaggcaaa gaacttgcag acgatgcaaa ggaagcggtt gaaggtgctg
     3841 tagatgccgt taaggaaaaa ttaaaataat taaaaaacca gctgtaagct ggttttttta
     3901 atggtgtgat tttgttagga aaagactcaa taggtaataa ccgtaggtgt taggtatgct
     3961 tgaacagttg agtacgattc tcttcaatca tatagcacgc gtcacaaagt ttttctaaca
     4021 tatcaaactc atgactaata atgatgagac ctaaatttct atcctttaca atctccaaca
     4081 ggcttttcca tacactagct tgtgtaatgc tatccaacat agtagtcatt tcatctgcaa
     4141 taaggtattt cgtctctgga tgtaatgaac gcacaatcga aaagcgttgc aattcccctc
     4201 ccgagagttc actaggacga cgctttagcc atttttcttg aatgccaaaa gcatctcgca
     4261 aatcttgact tggatagtag gcttcttcca aacttttttt cataggccat aaaggattca
     4321 tggtttgttc aggatgttgt tggataagtt gtacaggtct aaatgctttg ttaggcaaat
     4381 gactgccatc aactaatact tcaccagatt taggctgcaa aaaaccagca agcactctgg
     4441 ataaactcgt ttttccacac ccactttgtc caaatatccc taagatttga ccaggtgcta
     4501 cctctaaatc aatctcctta aaaagccatt gatctttttt atgataaaag ccaagctttt
     4561 tagcctctaa ggtcatgagt aactcctttc aaaaagtctt gctgagggag tgtgcgccat
     4621 aaacgtctcg caaattctgt ttgtaattgc tccccacctc cgctaaaaaa gctagctggg
     4681 gctgtttcaa tagcttttcc ctctttaaaa atagtaatac gatccgcaat ttgactagct
     4741 gctacaatat catgggtgat aaatatgacg cttattcctt tatctgcaaa ggagcgtagt
     4801 tgatctaaaa ccatttgcag agcatctgga tgtaatccag gggtgggctc atccgcaata
     4861 atcaaagaaa ccgtatcact aatacacgtt gtaaacaaaa cacgtcggag cattccgcca
     4921 gaaagttgga aaggatacaa gtcaccatca ctttctttta atccaaactg ttgaaacaat
     4981 ccttcttgag tagccttagc attttctgag atacccaagc gcacctgatg cttgactttc
     5041 atagatggat ctaaataatt aacggattgt ggaatcaacg tcatttcttt tcctcgcaac
     5101 tgtttgatgc gtttagaagt tagtgattga ccacgataaa tcatatctcc tgttacagct
     5161 gcatttttag gaagaatatc cataatagca tgtgctaata aactcttgcc tgaaccacta
     5221 gcacctataa tagctaataa ctcacctttt ttaacttcta aattcagcgc ttggatcggt
     5281 gtggattgaa atggttttaa aaatcttccg tattgagtga aggtgatgga gaggtcttta
     5341 atgcttaata atgtttctgt catatctcta cctcctaaaa atgatccgtt tgagggtaaa
     5401 agagtttctt taaagattct ccgatagtat caaaggcatt gacaaccaaa ataagataaa
     5461 ggcctggaaa aatcaccaac caccaattgc caagagagat atgcttagct gcctctgaca
     5521 aaatgatacc aaccgaaggt tgttcggcag aaaggccaaa tcctaagaaa gtcatggatg
     5581 cttcatgcaa gatgacgtgc ggaaataaga ggataaaccc aatgaaaatt tgagaagcaa
     5641 tcaaaggcag gatatgatgc ctcacaatat aataaggcgt ttttcccatg cttttagaga
     5701 gctggacaaa ggctttattc tttagatcat agacttcatt gcggataagc cttgctagag
     5761 agggccaatg ggtaacagct gttgcaatga taaccccttg agcccctttc ccaacaacaa
     5821 aagaaatgag aatcataaaa atcaaatgag gcataccaat aaacaaatca accaaccagg
     5881 ctattatttt atcaataagg ctatttccta gacctgcaag cactccaaaa acggtcgcaa
     5941 gaaagactcc cataagggcg cctaataagc cgacttgtaa agagaaataa agccctttaa
     6001 tcgttctgac aaacatatcc ctacctaaac catctgtccc aaaaagatgg tttaaggaag
     6061 gagcgaggtt gcgtaaagct gcattggttt ccaaaggcgt cctatagaaa taaaggttta
     6121 aggctagaat actaagaatg agagaaatgg cgatacccag ttgccataaa accatcgttc
     6181 gacgtttcaa tatcatactt ttctccttaa ctgtggattg atgatgctat ttaaaatatc
     6241 cgcaataaga ttgcccgcaa aaacaaataa tgtccctatc atcacaatag ctagaaggag
     6301 cggtgtatca cttttaagtc ctgcttcagt gagggtagac cctaagccag gatatgagaa
     6361 aacttgctca gcaagaacag atcctccaaa caattctcca aaataggaaa aatgcagtgt
     6421 aatagctggt acgatagcat ttctaaggca atgatgttta aaaatttgcc actgtgtttc
     6481 cccacgcgct ctggcaaata agacatattc actagaaagc accgacatca ttttagttct
     6541 cgtatgaagg gtgacattgg caatgcctag aatacttagc gtgaaaacag gtaacataag
     6601 gtgcttaact cgatcagcta acgtaatatc ttgactcaaa gtgcctatcg gggaagaaat
     6661 accaatcggg aaccacccca gctggacaga aaagattaat aaaaaaatga gtccaatcca
     6721 aaacgttggt actgatatct gaaggtatga aaaccacctg acaactcggt caagtaattt
     6781 cccttgatgg aaagcggata acgttcctaa gataaatcca ataagacccg ataagatcca
     6841 agagagtccc ataagtatga aagaagcacc tgcccgtgat ctaataatat cactaacagg
     6901 ttgccgataa acgagcgagg tccctaaatc tccctgtatc acatttttca accaaataaa
     6961 atattggact agagctggct tatccaagcc atagtggtga gcaatcgctt tgtactgagc
     7021 aggggttagt gatgtgtcat aattgacact tgccatgact ggatctactg gagattgttt
     7081 taacaaaacg aaggtcaaaa cagatacccc aaaaataagc gtgacacatc tgatgatttt
     7141 ccagatgata ataatggtag tacgtttcac aatgaaatct ccttaatcga taagaaaagg
     7201 agccgaggaa acgatcagca cagttttgtg tatcttgttt tctcagactc caaacttaaa
     7261 gtcgctgtat taactaaacg cgttacttag ttgattcatc ccaagtccac tcggcaatgt
     7321 tagtcaataa tgaccaatca tgaccatgac tgtggacgcc ttgtttacct acattgatac
     7381 gtttatcacc aatataagta tggttaaggc tcaccaacca tacatttggc aaatctccaa
     7441 gagtagaagc acctgttttg ccatcccact gcgctaactt ccaatattcg ttagctttgt
     7501 caaggtcaga agatgtcatt gctttgtcaa ggtacttagt cacggtagga ttgttataaa
     7561 acgtaatatt ggtccaacct ttccctgcta ggcttggatg atgcgattca taaaattgct
     7621 gcgcgtgatg acgtcctccg gcataaagta aggctgagtc atgtgacttc gttgccattt
     7681 catcccagtt actagctttg agtttaatag taatccctag ggccttggct tgctctgcta
     7741 cttcaacggc taagttcgct cgcaattgat cattagtagg gtagtacaga tcaaacgctg
     7801 catcaaggtc acctttttta cggctaccgt ctgcttgttc tttccatccc gcttttgtca
     7861 ataattgctt agctttagct actttattat ctttaatggc tgtttttgga ttccaaaatg
     7921 gtgttttatc aataattgaa taagctggtt taccataacc atttaaaacc gtatcgagaa
     7981 ctttttgcct atttaaacca atagtcaagg cttttcggat tgctggatca ctagtgacat
     8041 catttcctac aggataacca tcaggagaat cagtgatgac gccctttttc acataaggta
     8101 atgataagcc gcgcacatca tttgatggaa tatcaaggag gcgggtgcct ttgacttttt
     8161 tatcagcaag ttctggcgtt gcgtagatca tatcaacatc accagattct aaagctgcta
     8221 gtgctgtgtt ttcatcaagt aagacccaag tccatttttt aaagtatggt tttttcccat
     8281 gccaataagg gttacgaaca aaaatagctt gttctccagc cttatattct tttaccatgt
     8341 aaggtcctga accgatagga ttgctcttat acttatcatt gtaatgtttt ttagggacga
     8401 ttgggatttc agtcaactgt gctgtaaatg tcgaatgcgc ctcagtcaaa tggatattga
     8461 cctgattttt cccaactact tcaacgttct taatgaaggt tagatcccaa gcctttccat
     8521 ctgctttcaa catatcataa gtaaacttaa catcatcagc agtaacaggc tcaccatttg
     8581 agaatttaaa atcatcatgc aagtcaaacg accaagtcag cccatcttca gagagatggt
     8641 atgttttagc aagctctcct tttatatcta gttcaggaga acgtttcaat agagtgctat
     8701 gagtgatatt cccttcattg tggactccat aacggtcctt tggatcgaat tcatgaggga
     8761 gctttgcccc catagaaacg acaagttcgt cttttggacg ttgtttgcgc tgacgttctt
     8821 ttgtttgagg cttttgttgt tgacatgcaa ctaaaataag cccagtcaaa aataacgtga
     8881 taatagagaa gtattttagg tattttgaca caatcaaatc tccttat
//
LOCUS       DAUGJR010000054         8239 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUGJR010000054 DAUGJR010000000
VERSION     DAUGJR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8239
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.054"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            151..849
                     /locus_tag="VH800_001586"
     CDS             151..849
                     /locus_tag="VH800_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8362640.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            complement(966..2528)
                     /gene="ffh"
                     /locus_tag="VH800_001587"
     CDS             complement(966..2528)
                     /gene="ffh"
                     /locus_tag="VH800_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEQ8362641.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENHNDYVLIDTAGRLQIDEKLMGELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(2543..2884)
                     /locus_tag="VH800_001588"
     CDS             complement(2543..2884)
                     /locus_tag="VH800_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEQ8362642.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            complement(2973..3671)
                     /locus_tag="VH800_001589"
     CDS             complement(2973..3671)
                     /locus_tag="VH800_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8362643.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            complement(3754..5187)
                     /locus_tag="VH800_001590"
     CDS             complement(3754..5187)
                     /locus_tag="VH800_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362644.1"
                     /translation="MLRKKRILGLFRLVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKEPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKCYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            5354..6916
                     /gene="guaA"
                     /locus_tag="VH800_001591"
     CDS             5354..6916
                     /gene="guaA"
                     /locus_tag="VH800_001591"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEQ8362645.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            complement(6958..8181)
                     /locus_tag="VH800_001592"
     CDS             complement(6958..8181)
                     /locus_tag="VH800_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8362646.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
BASE COUNT         2464 a         1570 c         1462 g         2743 t
ORIGIN      
        1 tacacgaatc tagtcgctat gttttaggtg ttcccccttt ttgacagtgt tactatcaca
       61 tgaattaatt gtagaaaatg ttacacttgc tttcgtttta tttttttgat actattagta
      121 aagttataac tttactaaag gagctaccaa atgttttctg gacatcaact aaaaacagca
      181 cgattatcaa agggaataac tcaatcagaa ttgggaagat tgttgcatgt caataaaatg
      241 acaatatcta attgggaaaa aggtaagaat ataccaaatg aaaaacattt aaatgcctta
      301 ttgcatctat tcaatgtgac atctgattat ttcgacccaa actatagatt gctaacgcct
      361 tataaccagc tgacaatatc taataaagaa aaagtaattg gctattcaga gcgattgtta
      421 aatcatcaaa tagacaaaaa atctaaagat ctcatagata aaccatcaca attatatgct
      481 tatcgggtct atgaaagttt atctgctggt actggttact cctattttgg tgatggtaac
      541 tttgatgttg tcttttacga tgaacaatta gaatacgatt ttgcgtcttg ggtttttgga
      601 gattctatgg agccaactta tttaaatggt gaagttgttc ttataaaaca aaatagtttt
      661 gattacgatg gagcaattta tgcagtcgaa tgggatgggc aaacatatat caaaaaggta
      721 tttcgtgaag atgagggatt acgtctagtg tccttaaata aaaaatattc tgataagttt
      781 gctccctata gcgaagaacc tcgcattatt ggcaaaatta tcgctaattt taggccctta
      841 gaaatttaag ttagattgat aatgaactca tcatggtatg taacacggtc ttccgtaatt
      901 ttaataatct tgtatacaag ataaatgaat ttcacatcaa aaagagacga aaattttcgt
      961 ctcttttatt ttcgtttttt ctttgctttt tttagtttgt tagcctgccg tttcatggcc
     1021 tgtttcatgg caaattggcc aatttttcct ttaaaccctt taccaaatag ttgactcata
     1081 tccatatcac caccaaggcc agataaatca ggcataccac cttgtcccat cattccttct
     1141 aaggaagaca tatctggcat accagcaggc atgtttttag gaagattatt gggattaata
     1201 cccatatctt tcatcatttt agacatatcg cccgacataa ccccttgcat catgcttttg
     1261 gcttggttaa agtctttgat aaatttatta acttctacaa agctgttccc ggaaccagct
     1321 gcaatacgac ggcgacgact cgggtttagt aagtcaggat tttcacgttc agcgggtgtc
     1381 attgaagaga caatagcacg tttgcgagca atttggtttt cgtcaacttt gatattggcc
     1441 aaagctgggt taccagccat tcctggaatc attttcaaga ggtcttccat aggccccata
     1501 ttttgcactt gatctaactg ttcaataaaa tcattgaaat caaaggtgtt ttcacgcatt
     1561 ttttcagcta actctaagga ttttttctca tcatattcct ggctagcttt ttcaatgagg
     1621 gtaagcaaat cccccattcc caaaatccga ctggacatgc ggtctgggtg aaatgtttca
     1681 atatctgtga ttttttcacc aatacctgta aatttaattg gtttcccagt gatttcacgg
     1741 acagatagcg ccgcacctcc acgtgtatca ccatcaatct ttgttaacac aacccctgtg
     1801 atgctcaact gatgattaaa ctcgtaggct acattggcag cttcttgacc aatcatgcta
     1861 tctacaacca aaagaatttc atttggttgt gctaaagcct tgacatcgcg cagctctccc
     1921 atcagttttt catcaatttg caagcgaccc gcagtatcaa tcaagacata gtcattgtgg
     1981 ttttcacgag cttgttccaa accttttctg acaatatcga ctgctgagtg gtctgtcccc
     2041 atatcaaaaa caggtacatt gatttgttgc cccagtgttt ttaactgatc aatggccgct
     2101 ggacggtaaa tatcggcagc aatcatcagt ggtcgcgcgt tttcttcttt aattaattta
     2161 ttagcgagtt ttcctgcaaa agttgtttta ccagcccctt gcaaaccgac catcatgata
     2221 atagttggaa tttttggaga tttatcaatc tctgcagttt ctgagcctaa aatactcgtt
     2281 aattcttcat taacaatctt aagaatttgt tgtgttggat caagagtatc aataatctca
     2341 tggccaatag cgcgctcacg tacgcgctta ataaaggttt taacaactgg taaagcgaca
     2401 tcggcttcta aaagagctag acgaatctct tttgtcactt cttgaacatc tgattctgat
     2461 aatttctttt taccgcgaat gtgtttaaac acatcttgca aacgttgggt taagctttca
     2521 aaagccatag tcaaaactcc tcttactctc tattgtcaat actggttaga atggaaattt
     2581 tttcttgcaa atactcatca tgagggtagt gagcaatcat gtcgtcaaag atttcacttc
     2641 gaacaacata atccgaatac atatgaagtt tcatctcata agtctctaaa attttttccg
     2701 tacgcttaat attatcatag acagcctgac gactgacacc aaattcatca gcaatctcag
     2761 ctaagctata atcatcggca taatacagtt caatataatt catttgttta tctgttagca
     2821 aagctgcata aaattcaaaa agggcattca tcctgtttgt tttttcaatt tccataatgt
     2881 tcattttatc atactatgat tgtttttaac agtagcaaat taattgcctt gtgctgttcg
     2941 tgtaaaaaag gaagtcataa atgacttctt tactaattat tttctaagta aaattcaaaa
     3001 cggtcaccga tatactgact gcggacatac tcaaaaggtt tgccgtctgt aaagtaagac
     3061 acctgagtta gagccaaaat ggcatgtcct ttagcaactt ccaagtagga ggctacacgc
     3121 tcacttgcta gcttagcgta gattgtctgt ttacttttac caatctcgta accatttgct
     3181 atcaatgagt gaaaaaagtg ttctgtaata tcagctcgtt taaccgtttt tataaatttt
     3241 tctgggattg aagcaatttc gtacaccaaa gggacactgt ctgcatagcg gatacgttcc
     3301 attcgaatga ccaagtctgt tttgtctaag ttcaattctt taacttcggt atcactagct
     3361 aattgctttt gataggataa taatttagag gagggttgtc gtccttggga gcgtataatt
     3421 tctgtgaaac ttgttgttcc tcgcattttt tcttgaacac gatgactggc aacataagta
     3481 ccacttccta tccgcctttc aagaatccct tcttctacta gtaatgtaat agcctgccgt
     3541 agagtcattc gactaacggt gaaatgttcc gctaaatgtc gttcacttgg taagcgacta
     3601 ccaattggcc agatgcccag atcaatgtct tttttaattg catcatgaat ttttatataa
     3661 gctggtaaca tgccacactc ctcaagtcgg ttattcatct attttatcat atttttgatg
     3721 aaaattgaat tgtaaatatt gaggtatttg gcatcaatta atgatattac ctgcgacaat
     3781 aaccggtgaa tttggtggaa aatgaatagg ttccataaac caactagtga gcttcgcttt
     3841 agtaacaatg gatgaggtaa aaacattatt taaaacccta ataactccta cttttgagga
     3901 atgctgacca atagaaccac tataggctct caggcaacca gtcggatcta tataaggtaa
     3961 aaattgattt tggcttacag taatattgtg acatagatgt cgagtttggt taaatgcttc
     4021 atagtttgga gcaatattac taagtagacc tccatcccat gcaaaatgat gaacagcagc
     4081 atcaaactga atgacttctg aaaaaaaatc atgcccttga gcctttgata gcagctgttg
     4141 gtcttgtact aattctggcg catagccaat aaattggttt ttctcaaaca atgaattttg
     4201 tagagatcct aaatcaaaaa tatgactatt acgcttatga accatagtaa atttgttatc
     4261 gtaaatatgc caatcagtac catgatcagc cataatcata aagtggtctc cttttttcaa
     4321 atcatttgct ttgaaatgca ctccagtcaa cacgagatta cgaacacctt gttcagcctt
     4381 tggtcctgta gggaatccaa accacaacat tttaccgtga ataatgaact ctgtctgatg
     4441 accaataata gctgtatcag atggaagctc aaaataatct ttttgtgaag gcaaagagcc
     4501 aatgtgaaat tgcccctttg gaaaagatat aacgctattt ggatgctgct ttgcataagc
     4561 gaaagctttt cgcaaaagac gattgttttg ctcaggggaa tttcctttat tgaacctaat
     4621 ataataaggt ttaacaaaat cttgctctga aattccatct aatcttagat tatctttcag
     4681 attaatatcg tactgatatc ctcctaacga atagtcatag cattttttaa cttgtttaat
     4741 agtcgctaat tgaccttgat atacttttat atgtggcttt ttagttaatg aagataattt
     4801 aacgatatct ccttttttaa acctcggttt atcaggctct ttcaggttat gttctggcaa
     4861 agaaacagtg acttttccta ttggaaatac cacttcataa tgataactca ctcggtaatt
     4921 ttcggctata tcttctacct gtttattaat agttccaatc cattgatgat atggaccact
     4981 tttttgtact tgaatagctt gtccaatgtg atagcgaggc tgttgatctt tgcttcgttc
     5041 cactattccg acagttgcta atatattatg aagtgttgca aaactattgg tccacgcaag
     5101 gtacgaaaca actaaactca acaataatcc taggaaaatt aattcaacaa gtcgaaataa
     5161 acccaaaatt ctcttttttc ttagcatagg ccctccctgt tgtcttaatt ccctttcata
     5221 gcctctattg taacataacg attacgtttt tttccaacga gctagagaaa ttgtaatgtc
     5281 ttttcgatga aaatatgcta caataagttg acaactatca acctgacggt tggtatagaa
     5341 tgaaaggatt ataatgactg aaatttcaat tttgaatgat gttcaaaaaa ttatcgttct
     5401 tgattatggt agccagtaca atcagcttat tgctagacgt attcgagagt ttggtgtttt
     5461 ctccgaacta aaaagccata aaatcaccgc tcaagaactt cgtgagatca atcccatagg
     5521 tatcgtttta tcaggagggc ctaactctgt ttacgctgat aacgcctttg gcattgaccc
     5581 tgaaatcttt gaactaggga ttccgattct tggtatctgt tacggtatgc aattaatcac
     5641 ccataaatta ggtggtaaag ttgttcctgc tggacaagct ggtaatcgtg aatacggtca
     5701 gtcaaccctt catcttcgtg aaacgtcaaa attattttca ggcacacctc aagaacaact
     5761 cgttttgatg agccatggtg atgctgttac tgaaattcca gaaggtttcc accttgttgg
     5821 agactcaaat gactgtccct atgcagctat tgaaaatact gagaaaaacc tttacggtat
     5881 tcagttccac ccagaagtga gacactctgt ttatggaaat gacattctta aaaactttgc
     5941 tatatcaatt tgtggcgcgc gtggtgattg gtcaatggat aattttattg acatggaaat
     6001 tgctaaaatt cgtgaaactg taggcgatcg taaagttctt ctaggtcttt ctggtggagt
     6061 tgattcttca gttgttggtg ttctacttca aaaagctatc ggtgaccaat taacttgtat
     6121 tttcgttgat cacggtcttc ttcgtaaaga cgagggcgat caagttatgg gaatgcttgg
     6181 gggcaaattt ggcctaaata ttatccgtgt ggatgcttca aaacgtttct tagaccttct
     6241 tgcagacgtt gaagatcctg agaaaaaacg taaaattatt ggtaatgaat ttgtctatgt
     6301 ttttgatgat gaagccagca aattaaaagg tgttgacttc cttgcccaag gaacacttta
     6361 tactgatatc attgagtcag gaacagaaac tgctcaaacc atcaaatcac atcacaatgt
     6421 gggtggtctc cccgaagaca tgcagtttga attgattgag cccttaaaca ctcttttcaa
     6481 agatgaagtt cgagcgcttg gaatcgctct tggaatgcct gaagaaattg tttggcgcca
     6541 accatttcca ggtcctggac ttgctatccg tgtcatggga gcaattactg aagaaaaact
     6601 tgaaaccgtt cgcgaatcag acgctatcct tcgtgaagaa attgctaagg ctggacttga
     6661 tcgtgacgtg tggcaatact ttacagttaa cacaggtgtc cgttctgtag gcgtcatggg
     6721 agatggtcgt acttatgatt ataccatcgc cattcgtgct attacgtcta ttgatggtat
     6781 gacagctgac tttgctcaac ttccttggga tgtcttgaaa aaaatctcaa cacgtatcgt
     6841 aaatgaagtt gaccacgtta accgtatcgt ctacgacatc acaagtaaac cacccgcaac
     6901 agttgaatgg gaataacaga ataaacatta aaagactcgc caaaatgagc gagtctttta
     6961 atgtttattc tttaactgtt ttcgtatttt gtacatggta ttagcaatat gataaagtgg
     7021 gctgacaggg agattaaatt ctcctataaa ttcttctatt gtcggagcaa agttggcctt
     7081 aaatttggta agtccatcat caagcgagcc ttctactcct cccatgttag cccaaataat
     7141 accatcttga taagcatcct gaaaaacatt aggatacagc agatactgag gataaaactt
     7201 cttaaaatca tcattcatcc cagcataaag catttccata acatttccat aagaaataga
     7261 taatatacct gctacaacaa cttcctcagg atattggtct gtaaagcctt caaattcagt
     7321 tatataacgt tctaaagaag ctttttgatc ttctaatttt tttaaacgct tcttttgatg
     7381 agcttgggtg cgagtaatat cttggttaat aagaattaat tgctggcggt attgatctag
     7441 tttttgagga atattcactt ttgctagatg taagtaggcc ttatccccat aagtagtcat
     7501 caacttttga aagtaagctt cgttacgcaa agaaatattt ttacgttttt ctgttaagga
     7561 gacaatcttg gaaaatttgt gaagttctga ttgactgaca cgatatgttt ttacaccacg
     7621 ctgcttagca tcttttatta aacgtctggt atgcttagga aattgcatct caaggttttc
     7681 ttgagtgtaa atattagctt ggaaacgagg ttggatacta tctgcaatct ccattgttaa
     7741 accagtccaa tgaacaccag cttcttggag attcttaata gctgctaaag ctaaaggttt
     7801 ttcttcttct tcctgtccca gtgcgtattg ttttaacagg atagctggat catatttgat
     7861 aaagagggcc tttttagttt taccataatc ctttagtgtt ttcatggtaa atgccaccaa
     7921 atcacggtca agataatcca tgactggccc tcttggaata taaataatgc ttcttccaag
     7981 tggcaatagc ttaatcaaaa gtgataaaga ggcaacctgc ttttcctctt tatagatacc
     8041 aattcgctca ttctgccatt gatttttgat ttttgcccaa tcactacctt gtaaaacgct
     8101 aatttgctga tgttctttaa caaaagagtc atgctcttct tctgaaatac cgatttttgc
     8161 ataaaacgtt aaattcgtca tttattgtcc ccatctattc gtaatcttag cagatgtact
     8221 tactaatcat ctttactgt
//
LOCUS       DAUGJR010000055         7434 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUGJR010000055 DAUGJR010000000
VERSION     DAUGJR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7434
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.055"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(155..1222)
                     /locus_tag="VH800_001593"
     CDS             complement(155..1222)
                     /locus_tag="VH800_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEQ8362647.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDGIPPI
                     SLTQKTTATTSENWHHIDKDGLIPLGISLEAAKEEFKKEVEESRLSEAQKETYKQKIK
                     TAPDKDKLLFTYHSEYMTAVKDLPASTESTTQPVEAPVQETQASASDSMVTGDSTSVT
                     TDSPEETPSSESPVAPALSEAPAQPAESEEPSVAASSEETPSPSTPAAPSTPAAPETP
                     EEPAAPSQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSL
                     VSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIAT
                     MTLMSLFGSLLVTKRQKETKK"
     gene            complement(1319..4813)
                     /gene="scpA/B"
                     /locus_tag="VH800_001594"
     CDS             complement(1319..4813)
                     /gene="scpA/B"
                     /locus_tag="VH800_001594"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEQ8362648.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTAVSEEAPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATI
                     RDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAK
                     KEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGA
                     MPEAQLLLMRVEIVNGLADYARNYAQAIIDAVNLGAKVINMSFGNAALAYANLPDETK
                     KAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPD
                     KQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIE
                     RGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENP
                     QKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKL
                     SGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFS
                     PRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYY
                     QATVQTDKVDGKLFALAPKALYETSWQKITIPANSSKQVTIPIDVSQFSKDLLAPMKN
                     GYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDA
                     KDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTF
                     AKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNV
                     VWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISS
                     GAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDED
                     LPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEG
                     HSNKPEQDGSDQAPDKKPETKPEQDGSGQAPDKKPETKPEQDGSGQTPDKKPETKPEK
                     DSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTKDQLPTTNDKDTNRLHLLKLVMT
                     TFFLGLVAHIFKTKRTED"
     gene            5247..6633
                     /locus_tag="VH800_001595"
                     /pseudo
     CDS             5247..6633
                     /locus_tag="VH800_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(7031..>7434)
                     /gene="sic"
                     /locus_tag="VH800_001596"
     CDS             complement(7031..>7434)
                     /gene="sic"
                     /locus_tag="VH800_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="complement-mediated lysis inhibitor Sic"
                     /protein_id="HEQ8362649.1"
                     /translation="TGYEKRDDWRGPGHIPKPENEQSPNPSHIPEPPQIEWPQWNGFD
                     GLSSGPSDWGQSEDTPRFPSEPRVTEKPQHTPQKNPQESDFDRGFSAGLKAKNSGRGI
                     DFEGFQYGGWSDEYKKGYMQAFGTPYTPSAT"
BASE COUNT         1929 a         1507 c         1571 g         2427 t
ORIGIN      
        1 catcttttat cacagcaact gaagagataa gcaaaagaca attgttgaca gctatttgtc
       61 ctaacttctt tttgatgagg cagcacatct aaaaaaatag agagaaccaa attggttctc
      121 tctattaaat aagctcttat cagtttaagt aatactattt tttagtttct ttttggcgtt
      181 ttgtgactaa aagactgcca aatagagaca tcaaagtcat agtagctata aagagtggct
      241 gtgctttttc acctgttgaa ggcaagtact tacctgactc atgggcccta acctgtcttg
      301 acaatgagcg atttggagag taagactgtt cttgctcttc ttttttatca gaagatctct
      361 ttgaagttgg ttgttgaacg gtttgttctg aaacaagtga agaggctgct ggtttttcag
      421 ctgctgaaga tggcttatca gagtctttag taacagctgg tggcgtctga gtctctgatt
      481 cagctggagt tgatggagac gggcttgtcg tagctgctac tgaagattct tcactctcag
      541 ctggttgaga tggagctgct ggttcttcag gagtttctgg agccgctgga gttgatgggg
      601 ctgctggagt tgatggagat ggggtttcct cagaagatgc tgctactgaa ggttcctcac
      661 tctcagctgg ttgagctgga gcctcagata aagctggggc cactggactt tccgaagatg
      721 gggtttcctc aggagaatca gtcgtaactg atgttgaatc acctgtcacc atcgaatctg
      781 aagctgatgc ctgtgtctcc tgcacgggtg cctcaactgg ctgagtagta gactcagtag
      841 acgctggaag atccttaacg gctgtcatat actcactatg atacgtgaat aatagcttat
      901 ctttgtctgg tgcagtttta attttttgtt tatacgtttc tttttgtgct tcagataaac
      961 gtgattcttc tacttctttt ttaaattcct ctttggcagc ttctaagctt atacctaaag
     1021 gaataaggcc atccttatca atatgatgcc aattttctga tgtagtggct gtagtctttt
     1081 gagtaagaga gattggaggg atgccatcta cggcataggc aacctttcct aaaaagagac
     1141 tcgcaattgc tatactcgtt accccaacgc tcagtttgcg aatggaatag cggctgtgtt
     1201 tgttattttc tgctctacgc atattgtcct cacatatcta tttttatact gctatgcctt
     1261 cttttgaaaa gaagactgat ctaactcatc atcaatagta gccatctgat cagttgtact
     1321 aatcttcagt gcgttttgtt ttaaagatat gagctactaa tcccaagaag aaagtggtca
     1381 taactaactt aaggagatgt aaacgatttg tatccttgtc attagtcgtt ggtaactgat
     1441 cttttgttga tgcttttgta gctaaagcac gcttagaaga tcgtttctct agagtacgag
     1501 aaggttgacc tttttgagga gttttacctg gtgtttgacc tgaactatct ttttctggtt
     1561 tagtttctgg ttttttatct ggtgtttgac ctgaaccgtc ttgttctggt ttagtttctg
     1621 gttttttatc tggtgcttga cctgaaccgt cttgttctgg tttagtttct ggttttttgt
     1681 ctggtgcttg atctgaaccg tcttgttctg gtttattaga gtggccttcc aatagcttag
     1741 tcactggtgt ataagtgatg ttaccagcca tatcttcaac aacataagta aagtctgaca
     1801 ttttcaatgg aacagtagcg ccttccattg tttcagcctc ttcaggaaga gtaaaggtac
     1861 catcttcatt tggagaaata tactctgttg ttggcagatc ctcatccata taagtgtaag
     1921 caatacgctc acggtaaacc ggttggctgg tttttggttt agatgcaagt gtcaaacgac
     1981 gatcttctgt tgagaatgtt gccgatgttg cgacttcagg tgtcgtattg tctacaatca
     2041 catcaaaatc agtgtgttgt tcttttgcac ctgagctaat cggagtgtag cgaacacgat
     2101 aggtgtatgt tccgttagca acaactttgc cgtctttatc tttaccgtcc caacgcgttt
     2161 tttcaaaacg ggttgaacca agtgtgcttg ccaagtcatt gttgtagttt ttaacaactt
     2221 gctcggttac ctcacttgtc caaacaacat ttccttcttt gtccaagact tcagccacaa
     2281 ggtttttagc attacgcaag aaagtacctt ggaattggac ataatctctg ttaccgtccc
     2341 catttggaga gatcgcagca tatggcttgc cattagcgtg acggtggata tagtagtggc
     2401 tatcatcgtc ttgttttgca aaagtacctg caaaaatggt ttctgtgatc tctgaagatt
     2461 cgatatcctc tatgttttca accccttctt tgacagcttt aataatcgtc catggattag
     2521 actctgtagt aagtgctgta aagttatttt tcagagcgta aaactgtaat ccatcaccat
     2581 ctaattggtc tttggcatca ctatttgctt catgatagta gctgctaccg tctttgctat
     2641 catagattgg tttttctaag gctgacagat tgccaaaatc acctcggaaa ccaatatagg
     2701 gaatactcat aagctcttct tttgtaggat cttgtttgaa acgaacaaaa ccttctaaga
     2761 aatagccatt tttcattggg gcaagcaagt ccttgctaaa ttgactaaca tcgattggaa
     2821 tggtgacttg tttgctgcta ttggctggaa ttgtgatttt ttgccatgat gtctcataca
     2881 atgctttagg agccaaggca aagagttttc catctacttt atctgtttga acagttgctt
     2941 ggtaatacaa ctcttgaggt ttatcagatt tgttgtgaac tgttactgtt acttcaaatt
     3001 tatcagaaac attgttcagg tgaaccttgc ttgaggtatt atccttatct gtcacataca
     3061 tcgttgctgc tgaagctttt ttagcatcga ctgctcctgc tccttgttgg cgaggagaaa
     3121 aataagcttt ttcatcttca tcatataagg cagttgctga gctcatcaat acttttttag
     3181 ctaaatcaag acgctctgat ggtgtcatat caggatactg tgtctcatat tgcttttgca
     3241 acagtcccat gatacccgct actaatggcg cagacatact agttccagaa agtttggcat
     3301 acttgttgtt agccactgat gacaaaatat cttggccggg tgctgcaata tctggcttaa
     3361 tattgccgtc agctgtcaga ccccagcttg agaagcggct tagtttggtg ccacttgctg
     3421 ttggcaatac cttaggtgtc gcattgaagg tgatggtttt ttggggattc tcttttaata
     3481 agagaccatc ttttcgactg ataaaggccg caggcatctg atcaacattt ggcaattcaa
     3541 tcgggaagcc cttgtcctga ttgtcataga tcaagactcc tacagcacca gcttttttag
     3601 cgtttgcaat cttatctttg aaatcaatat cgccacgttc aataagggca atcttacctt
     3661 tgacatcctt aaaatcatcc tctttcatcc cacgattagc ataagcatag tcgtaagcct
     3721 tgtttggctc aaaacggttt gttgaaagaa caggcatttc tttatcttgc tgatcggctg
     3781 ttttgaccgt agcagtttca gtgagctgtt tatctgggct gtaagaagca actgtcaatg
     3841 ttgagtctgc cgctgcaggt gtcccaacca ccccataatc aggatgatct gctagaggta
     3901 gacgggtctt gcccccaaag ctactatcat taccagctga ggtcacaatg ctaacacctt
     3961 ttgatttggc atagtcaaag gcttttttgg tttcgtctgg aaggttggca taggctagtg
     4021 cagcattacc aaagctcata ttaatcacct tagctcccaa gttgacagca tctatgatag
     4081 cttgagcgta gttacgagca tagtctgcta gtccatttac aatttcgaca cgcatcaaaa
     4141 gcaattgagc ctcaggcatc gcaccttcta ggcggtaagg ttctttcgtt tcagatggag
     4201 catttcctga caagatccct gacacgtgtg tgccgtgctc ttgatcgaca gcggttttac
     4261 catctttact atagtcgtgg taataagcaa ccttatcatt gacccactcg ccataggtaa
     4321 taccgtgctc ttttttagct ttttcaagat cttcttttga ttggtaacgt gctttggttt
     4381 tgtctgttaa gcgccacgct tcatgatttt tatcaaaacc agcatcaatc actgcaacaa
     4441 cagtcccagc tcctttgcct gctttttcct gcagggtttt gacctgagaa gggtcgttca
     4501 aatccctaat agtcgctttt gaggttgctg gtgtatcagc agttttagca ggagcttgag
     4561 gggctagatc attagcgtca tctgctattg tttcttctgc gtcatcagga gtttgtgggg
     4621 ttttggtttc ctttgatgat ggtgcttcct cagaaaccgc tgttggttgt ggggtttcta
     4681 cagcttgttc ggtagcagga gtgtcttctg tcacagtatt tgctttaatg tctgattgtg
     4741 cattgagcaa gatgctcgta gacatgagcg caatggcaag tttatcaaat ggtaattttt
     4801 gttttttacg caatgtgtcg tcctttcctg atgagagact ttgtctttat gaccattaag
     4861 aaaagagaga atcaaacgat tctctcctag ctgtccatct gtgcgtagag aaataaggat
     4921 aacgtctttt ttaaagagca aacaggggtt atttgcatat gatacagcta tttttcttgc
     4981 ttttgtcata atgattaaat gtatctcatt tatcaattat attaataaca tatttattat
     5041 aaaacaaaga tgattattag taaaggtcag ctttttaaga gttgcttagt ttgtgacctc
     5101 cttatcctca ttcttttaga cataaaagag agaaccgatc ggttctctct tcagactgaa
     5161 gacaaagtcc ttagaatcgc ttttctaggg gctttttatg atatttagga gtataatata
     5221 agaaaaagga cttgtgaggt tctcctatgt tacacaaaga aaaacctgat tataaccgca
     5281 atcagtacgg tttctatacc cttgaccagt tagtgcctga tgaacatttc ctgcgccaag
     5341 tggaagctgt gattgacttc gacttcatct atgacctagt agaagacacc tattcgtctg
     5401 ataatggtcg ccctagcctt gatcctgtca tgttggttaa aatccctctg attcagtgct
     5461 tttatggcat tcgttccatg cgtcagacca tcaaggatat tgaagtgaat actgcctatc
     5521 gctggttttt aggtttgact ttggatgaca aggtgccaca tttcacaacc tatggcaaaa
     5581 attattcccg tcgctttcaa gaaaaaggct tgattgagtc catttttacg catattgttg
     5641 ggctatgtat caatacaggc ctgattgacc cgacggagat tttcatagat gggactcata
     5701 ttaaggctgc ggctaataat cgcaagttca tcaaccgaga ggtggaaaaa caagccaagt
     5761 tcatgagtga acagctagaa atcgaaatca atcgggatag ggagaagcat ggaaaaaagc
     5821 cgctagggcc cgccaaagag ctagagcccg tcgctaagaa aatctccaca accgatccag
     5881 aaagtggctg gtttcacaaa ggtgatcata aggaagtctt cgcttattct gctcaggtgg
     5941 cttgtgacaa gtatggatgg gcgcttgctt atagtgttga ggctggcaat atccatgata
     6001 gtcaggcttt tcctgcactt tttgccaagc ttgaaccctt gaaaccacag tttattattg
     6061 cggattccgg ctataacgtt cccagcattg ccaagtttct gattgataag gagatcactc
     6121 ctgtccttcc ttacacacga ccaagaggaa agaaagacct tctacgtccg aaagaattga
     6181 tttatgatga gcactttgat tgtgtcatct gccctgaaca tcaagccttg acctaccgca
     6241 ctacgaccag agaaggctac cgagaataca aaagtgaccc tgtaatttgt gccaattgtc
     6301 ccctgttatc tgtatgtacg accagtaaga actaccaaaa agttgtcaca cggcatattt
     6361 ggaaagacta tttggcacag ccaaggaata ccacaatctc tgctatacga gagagaaagg
     6421 caagtccaaa atggaagata cggttggact gactttggca tgcttaaatc tcaaaaaact
     6481 ggtcaaaagg atggcgggag agccttttta ttttgttcag atgaggtggt ttaagcacgg
     6541 aaacagccat ttttatctaa aaacactaaa aaagacaaac accaaatcga tgtttgtctt
     6601 caatctgttc tagagacttt ttctttattc tgagcgatag ttgtcataca ttgctttttt
     6661 agatgagtac actgcactct tttataatgg ttttagtgtc cgtggaataa agagttcagc
     6721 attatactca ctattgttaa cttcactatc actttattca atgtatcata gtctaaccaa
     6781 gcttgctagt ttccccaatg atagtcacca gcaattcagg tagtggcaat atgctacccg
     6841 tctcctaagc aagaatcttt ctcggactca gatagtccat agcgcagcgc atcaatcact
     6901 cctatcagaa attttagcaa gacataaata acattttaca gccctacatc acctatggaa
     6961 tcagaatttt tcgtaaaaat ccctaagaag cgtggcaaaa gcagcactaa actattccta
     7021 tcgcatccct ttacgttgct gatggtgtat atggtgtacc gaaggcttgc atgtaacctt
     7081 ttttatattc gtctgaccag ccaccatact ggaaaccttc aaaatcaata cctctacctg
     7141 agttttttgc tttcaagcca gctgaaaacc ctctatcaaa atctgattct tgtggatttt
     7201 tttgaggagt atgttgcggt ttttctgtca cacgaggttc acttgggaaa cgaggggtgt
     7261 cctcagattg gccccaatca gaggggccag atgataatcc atcaaagcca ttccactgag
     7321 gccactcaat ctgaggaggt tcaggaatat gagatgggtt tggtgattgt tcgttctcag
     7381 gtttaggaat atgtccaggt cctctccaat catcacgttt ttcataccct gtac
//
LOCUS       DAUGJR010000056         7429 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUGJR010000056 DAUGJR010000000
VERSION     DAUGJR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7429
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.056"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(15..224)
                     /locus_tag="VH800_001597"
     CDS             complement(15..224)
                     /locus_tag="VH800_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8362650.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
     gene            complement(214..1059)
                     /locus_tag="VH800_001598"
     CDS             complement(214..1059)
                     /locus_tag="VH800_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEQ8362651.1"
                     /translation="MDISIEFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLETI
                     LDSEFSTERESLIAEIDELESQLTTLNQELQELGNIPNLSSEYLENYSKLTATINALK
                     EQNEAYLKESGLSKEKSETDADLKRSTEDILLDLEVKINSKMREVNNILYPDIRKAPQ
                     INLNAHNSYSFYTPDDDGTGTKFKGMIVFDLVMLYLTNLPALAHDSLLLSNVSYQATE
                     ALLKLYDQSRSLNKQVFLVFDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGE
                     NSDEI"
     gene            complement(1144..1872)
                     /locus_tag="VH800_001599"
     CDS             complement(1144..1872)
                     /locus_tag="VH800_001599"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEQ8362652.1"
                     /translation="MLIEMWSPVFKKHGEIREPICFHHGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARRYAFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDI"
     gene            complement(1863..2087)
                     /locus_tag="VH800_001600"
     CDS             complement(1863..2087)
                     /locus_tag="VH800_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362653.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSRNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            complement(2087..2980)
                     /locus_tag="VH800_001601"
     CDS             complement(2087..2980)
                     /locus_tag="VH800_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362654.1"
                     /translation="MTNMLDFPYHHEFIEFLGRWTHILIALPKRHHGQVDTAIPRYLL
                     VTIREKTGIVKLTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEALNLIALCPDGFLTYQADRRKKIVTTLKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYNISYDSKQLTDKISPENNRTLYQLVKNQVI
                     DNYLTIQKIIVNLDKQGKIDYEKIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHLATL
                     QDIYFCQMIVSYFIQKCEVLE"
     gene            2996..3172
                     /locus_tag="VH800_001602"
     CDS             2996..3172
                     /locus_tag="VH800_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ8362655.1"
                     /translation="MGQNVVMRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCICRQG
                     DEASVYDERGILSF"
     gene            3227..3529
                     /locus_tag="VH800_001603"
     CDS             3227..3529
                     /locus_tag="VH800_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEQ8362656.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLFQLKENA"
     gene            3529..3834
                     /locus_tag="VH800_001604"
     CDS             3529..3834
                     /locus_tag="VH800_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8362657.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADDLLERLSQGM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            3853..4125
                     /locus_tag="VH800_001605"
     CDS             3853..4125
                     /locus_tag="VH800_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362658.1"
                     /translation="MELVKTIQIGDDIYPPIPDLFGIQENQEFNLYKSTDGTLVLSPS
                     DSKLSADHQSISSDEQMTTAVEQARLDEIATSVLSRHLDAFKELTE"
     gene            4230..4682
                     /locus_tag="VH800_001606"
     CDS             4230..4682
                     /locus_tag="VH800_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8362659.1"
                     /translation="MGLLDLIGRKRARDKPQNSYEGQDFSYLFGRTTSGENVDEFKTM
                     QTTAVYACVRVLAEAVASLPIHIYERTENGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TIMSHLLIWGNAYVQIIRDKSGMVSLLLKQKASVLIRKLLLIIWQRMP"
     gene            4748..5062
                     /locus_tag="VH800_001607"
     CDS             4748..5062
                     /locus_tag="VH800_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362660.1"
                     /translation="MPRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNGNL
                     SIDTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVR
                     ID"
     gene            5479..5817
                     /locus_tag="VH800_001608"
     CDS             5479..5817
                     /locus_tag="VH800_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEQ8362661.1"
                     /translation="MKPPFTVTNTMLNKVVEISKIIGNLELQVQKDLKLRKENRIQSI
                     HSSLAIEQNSLTVEQITAIIDGKRVLGNPREIREVKNAYEAYEEILTLTPYDESHFFK
                     MKKFQQYIYR"
     gene            5841..6665
                     /locus_tag="VH800_001609"
     CDS             5841..6665
                     /locus_tag="VH800_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine ligase"
                     /protein_id="HEQ8362662.1"
                     /translation="MGLGSDSLPVKISLFDVDTYLADSMQFHLEYILRLFPKSGVHYL
                     MPTFRGEAVDHRHLSQFYHSECEIEGDLHYVMNLVDRYIKFLVSEILRECRDSIFAIT
                     KDVSHLESFIDRKIPIITFEEACTILENEIDSLEYNDEHHFYVLTDVGEKKLMEHFEG
                     VVWVKNYPCKSVPFYQRFSTDHLFAYNADLLLGIGETVGCGERCETYEEVVENMNYLQ
                     VDASEYSWYLEMKKTRPMKSSGFGLGVERLIAWILKCDDVRKVQLISRENGIDYLP"
     gene            6679..>7429
                     /locus_tag="VH800_001610"
     CDS             6679..>7429
                     /locus_tag="VH800_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEQ8362663.1"
                     /translation="MKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFV
                     ETIETSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSF
                     RFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNF
                     SELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIY
                     TPLGITKKIVDEKLFMDEIGHIFPSNLNKEEK"
BASE COUNT         2353 a         1141 c         1532 g         2403 t
ORIGIN      
        1 tgcttttttt atttctagat attattatct acaatttcta ctatatcttc aatcttacaa
       61 tcaagtgcaa tacaaatttc caataaaata tcagtagtga tattttcccc ttttcccaat
      121 tttgcgatcg tggaagaact aatcccagct tcttgcctga gctttgtttt ggtccaacct
      181 ttatcaataa gaagtttcca taatttattg taactaaatc tcatctgagt tttctccttt
      241 gttccatgaa ataccgtaga gttcatttcc gttactagag agtctcaata ccgtattttc
      301 tgacaagagt tgattagcat ctggagaata agagctggct ttatcgaaga ctaaaaagac
      361 ttgtttgttc aatgaccttg actggtcata tagcttcaaa agtgcttcag tcgcttggta
      421 gctaacatta ctcaagagta atgaatcgtg tgcgagtgct ggcagattag taaggtagag
      481 cattactaag tcgaatacaa tcatcccttt aaacttagtt cctgtaccat catcatctgg
      541 tgtatagaag gagtagctat tgtgagcatt taggttaatt tgaggagctt tgcgaatatc
      601 tggatataga atgttattga cttcacgcat cttactgttg atttttactt ctagatctag
      661 aaggatatct tctgtactgc gtttcaagtc agcgtccgtt tctgattttt ctttggatag
      721 accagactcc tttaagtagg cctcgttttg ttcttttagt gcattgattg tagctgttag
      781 tttagagtag ttttctaagt actcacttga aagatttggg atgtttccta gttcttgaag
      841 ttcttggttt agagttgtta attgactctc taattcgtcg atctcagcta ttagggattc
      901 acgttcagtt gagaattcgg aatctaaaat agtttccaat tttttgtggt aagcttcaac
      961 ttcatataat tttttgagat tagtatctgg gaagtattgt tgaagctctg ttaagtcaga
     1021 ttcagtagga tataagccaa attcgatact gatgtccaat agcttaagac gtctttgctt
     1081 gtcccgaaga ctgctttcta actccagctt agtatttcta agttggagtt tttgttgatt
     1141 tttttaaata tcatcagagt caattttatc ttgatgagta tcttggagat gtgctaaatc
     1201 atattccaat ctttttattt ctgagacatt tgcttcaaat tgctttttac cgccaaccag
     1261 gttggagatg aaggcatacc tgcgagcatt acgaaaagtt gttaactggt cgctcttatc
     1321 tttcagacgt tctttgtatc gtgcaatgtt atcatacaaa ttaaacagtt ggatgagagt
     1381 agtaatagat tcagaagatt tttggctcga ataaacttgt aaggggaaat cggtattttg
     1441 attacttttt cctgcaatcc taaagaagcc actcatagct aatcggaatg atagctctgg
     1501 agaatctaaa tgatatcgtt tcttaagttt gttaagaaaa attcctaggt ccattgtttc
     1561 accggttgga gagtagctct tgtcacacac tagaatgata tctgggttgg ccgtatctct
     1621 tgaaaaataa aactttttct caaattgaaa gcagaagtag ataggatgat cacctaattt
     1681 tttaaccgca attgatttta gatagctatt acctccaaag atgaaatcaa tggctaatag
     1741 tgaggaggat ttgccgatag agttatcagc taaatccatc cccataatca cgtttaaccc
     1801 atggtggaag cagattggtt cccgaatttc tccgtgtttc ttaaatactg gagaccacat
     1861 ttctataagc ataattttac ttctccttca ttagacattt caatagcgtt caatgcatac
     1921 aagcaatcca ttatggatag aaaatctgta ggatcatcca actcttctga gatagcgtga
     1981 aagatatctt tgacgtttga gtttctactt ttgatttcat ttagcactct aggcaaataa
     2041 gcaagggtgc ttttttgata ggagtaaagt ttatttggta attgcattat tcaagtacct
     2101 cgcatttttg tataaaataa gagacaatca tctgacagaa gtagatgtcc tgtagtgtag
     2161 ccagatggag tttttccgaa atagtattga aaatagccag attattatgc ttggctgctt
     2221 ttaacttttt atacatcgat cgcgtttgat attggatttt ctcgtaatca atttttcctt
     2281 gtttgtccaa atttacgatg attttttgaa tggttaagta gttatcaata acttggtttt
     2341 taaccaattg ataaagcgta cgattgttct caggtgatat cttatcagtc aattgcttcg
     2401 agtcatagga gatattatat tcatcacatt ttagtttatt gagactagtc aaaactgaaa
     2461 caattccact gtctaacttc atatcagaaa tcgcttgttg gctgttatgt gcagagacta
     2521 gaatcttttt aacatttttt agagttgtta caattttttt gcgcctatct gcttgatagg
     2581 ttaaaaaacc atctgggcag agggctatca gattcagtgc ttcagcgtcc ttatcttttt
     2641 caatggctga aacctcgtaa ttttctgctg ctaagttgcc actggttaga atgagtggtc
     2701 tatcacagcc tgggcatgca caacagttat tagattctgt taacaagaac tgcccgtatt
     2761 gttttttgag ttgattcgac tgggtagtga acgctgtatt ttgcacagtg gttaatttta
     2821 caatccctgt cttctctctg atggttacca gaagatacct tggaattgcg gtgtcgactt
     2881 gaccatggtg ccttttgggc agggctataa ggatatgagt ccaccgtcca aggaactcta
     2941 taaactcatg atggtaggga aaatctaaca tgttggtcat ccagtcctta aatggatggg
     3001 acaaaacgtg gtgatgcgac aagcccctgg aggcaacatc aagccagata aggaaaaatc
     3061 tgttgagaag attgacggta ttgtaggtct tatcctgggg cttgaccgtt gcatttgccg
     3121 ccaaggtgat gaagctagcg tctatgatga gcgagggata ttgagttttt agttgagtca
     3181 actctaaaaa cgtgatacaa tgtcgttaca aaaaaggagg ataaccatgg ctaaaacggg
     3241 aactttgaat ttacgagttg atgattcagt aaaaagtgcg gcagatgata ttttgaaacg
     3301 cttaggtatt cctatgtcaa ctgcgattga tatgtttttg aatcagatta ttttgactgg
     3361 gggtatccca tttgatgttt ctctacctga agcgcctcaa cgagttaatg ttgattacat
     3421 gagtcaggag aagttttatg ataagcttat caccagcttt gaagatgcga aaactggcaa
     3481 ccgtcaggat gtcagagaat ttctatttca attgaaggaa aatgcttaat gaaagaatat
     3541 caggtcacca tgtcggatga tgctaaagca gatttgctga gcatctatca ctatgttcgt
     3601 gatgaactct gtgcaccaca ggcagcggat gatcttcttg agaggttatc ccaaggaatg
     3661 ttatcactat ccatttttcc tgaacgttgt gccatcattg aggatctgat tggaaaaggc
     3721 tataccttca gacaactgat tgtcaaaaaa tatcgcattg tatatcatgt tctggaagat
     3781 gaagttataa ttgttgcggt cgtctatgga tcacgtcata tgaataattg gtaaagtaag
     3841 ggagagtgat gtatggaact cgtaaagacg atacaaattg gtgatgacat ctatcctccg
     3901 atacctgacc tatttggcat tcaagagaat caggagttta acctttataa atcaactgat
     3961 ggaactttgg tgttaagtcc atctgatagc aaactatcag cggatcacca aagtataagc
     4021 agtgatgagc agatgacaac agctgttgaa caagcaaggt tagatgagat tgcgacttca
     4081 gtattatcac gacatcttga cgcatttaag gaattgacag aatgagaata ctaggttttg
     4141 taagaaagac tgttgattac tttgaaagaa atataccgaa agcacttcaa aggaggtgct
     4201 ttttttgtac cccaaaataa ggagggctta tgggactact tgatttaatt ggaagaaaaa
     4261 gggctagaga taagccccaa aacagttatg aaggtcagga cttttcctac ctctttggtc
     4321 gcacgactag tggcgagaat gtggatgagt ttaagactat gcagacgacg gcagtctatg
     4381 cctgtgtgcg tgttcttgct gaagcggtgg cgtcacttcc tattcacatc tatgaacgga
     4441 cagaaaatgg gaaggagaaa aagctggacc acccactgta ctttcttctt catgatgaac
     4501 ccaatccaga gatgtcctcc tttatctttc gagagacaat catgagccat cttttgatat
     4561 ggggaaatgc ctatgtacag attatacgag ataaaagtgg tatggtatcg ctactgctaa
     4621 agcagaaggc gagcgttctg ataagaaagc tgctcttgat tatctggcaa cggatgcctt
     4681 agaagcacga attgcagcac ttcacaaagc taagattgat gagttgaccg tctctagttc
     4741 agcatggatg ccaaggctta tctcccaaca gattctatca gagtatgtga agagcctaga
     4801 agttgaagct gataaggtcg ttattccagg acagaatact ccagtcttta gttgggatag
     4861 ggatgggaat gggaatcttt ccattgacac accgctccta aaggtgagag gggaaagtct
     4921 agcgacacaa gctgacctta caaccatctc tttaactcct ggtccaaagg gagaactctg
     4981 gcagacaagt gttgaaaggt tggatataaa agtagacaag cacatcagcc taaccttcaa
     5041 aaatggcgta cggattgatt gataaaaggc aagggcgtat caattcggca cgtccttttt
     5101 tagtttatct gtggtataat gaaagaagtt atattgggag ttgagatgca cgattcattt
     5161 gaattttgca ctccctaaaa agggtaaagg ttagattgta tgataaaact aatagcaaca
     5221 gaaataggaa taaagtggat aatacaataa aagttctaaa tagcttgaaa caaagggact
     5281 aggagtttga gtgggaattt taatactcta gggtaatttt atgtagagtg tttgaaaata
     5341 ataacgttaa aaagttagta atcgttaaag aatttaaaat aaattgtaat agtttatcgc
     5401 ttgttttatc gcttgaagaa cgagcgataa atttattttt atggtataaa taagaaaaaa
     5461 gattgtaagg agaaaatgat gaaaccacct tttacagtta cgaataccat gttaaataag
     5521 gtagtagaga tttctaaaat tattggtaat ttagaattac aagtacagaa agatttaaaa
     5581 ttaagaaaag aaaatcgtat tcagtctatt cactcatcac tcgctattga acaaaattct
     5641 ttaacagtag aacaaataac agccattatt gatgggaaaa gagtgttagg gaacccccgt
     5701 gagataagag aagtaaaaaa cgcttatgaa gcttatgaag aaattttaac gctaactccc
     5761 tatgatgaat cacatttttt taaaatgaag aaatttcaac agtacattta ccgataacaa
     5821 catcgtcaat cacaagtcct atggggttgg ggagtgattc gctacctgta aaaatttcct
     5881 tatttgatgt tgatacctat cttgcagatt cgatgcagtt tcacttagag tatatactta
     5941 gactttttcc aaagtcagga gttcattact taatgcctac ttttagagga gaagcagtag
     6001 atcatcgaca tttatcgcaa ttttatcata gtgagtgtga gatagaggga gatttacact
     6061 atgtgatgaa tttagtggat agatatatta agtttctggt tagtgaaatt cttagagagt
     6121 gtcgagatag tatttttgct ataacaaaag atgtaagtca tttggaaagt tttattgatc
     6181 gaaagatacc aattattacg tttgaagagg cttgtactat attggaaaat gaaatagatt
     6241 cattggaata taatgatgaa catcattttt atgtgttaac agatgttggg gaaaagaaat
     6301 taatggaaca ttttgaggga gtagtttggg taaaaaatta tccctgtaaa agtgtccctt
     6361 tttatcaaag gttctcaaca gatcatctat ttgcctataa tgcagatttg ttgttaggaa
     6421 taggcgaaac tgtaggttgt ggagaaagat gcgaaacata tgaagaagtt gtagaaaata
     6481 tgaattattt acaagtagat gcttctgaat atagttggta tttagaaatg aaaaaaacaa
     6541 gacctatgaa atcttcagga tttggtttag gagtagagcg tttaatagcg tggatattga
     6601 agtgcgatga tgttcgaaaa gttcaattaa tcagtagaga aaatgggatt gattatttac
     6661 cataaaggag gaagaaaaat gaaaaagaat attttaattg taggtggagg tccagagata
     6721 actatatgtt atgatttaat taacaatagt acggagtata atttcttttc agtatcagaa
     6781 attcctacga tgtatccaga gttgtttgta gaaacaattg aaaccagctt tagaaatttt
     6841 ggaaagacga ttgaacaaat taaagagctc aaatattcta ttgatgctgt tgcttgttgg
     6901 gatgaagctt taacgcatat agctgatgat atttcaaaag aattaggatt gaaccctatt
     6961 tcatcgctag attctcaatc attcaggttt aaagatcgaa tgagaatggt atgtgaagct
     7021 ggtggactaa aaatgcccaa atataaaatt atcaatcaat tttcagatac aaataaaata
     7081 atcaattgga aatatccatt aatagtgaaa ccaacctctt ttttagcaag tataggagtg
     7141 aaaaaagttt ataatttttc agaattacaa caagcagttt ctcaaatgct taatgtaaaa
     7201 tttccggttt acatagcttc aggggtatat gaattggggg aattatataa tttagaacct
     7261 agagttttgg tggaagagtt tattgatgga gaagaatata gcttagagag cgtggtaaga
     7321 aatggaatct atacacctct agggataact aaaaaaatag tggatgaaaa attatttatg
     7381 gatgaaatag gccatatttt cccttcaaat ttaaacaaag aagaaaaaa
//
LOCUS       DAUGJR010000057         7252 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUGJR010000057 DAUGJR010000000
VERSION     DAUGJR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7252
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.057"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            585..674
                     /locus_tag="VH800_001611"
     CDS             585..674
                     /locus_tag="VH800_001611"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8362664.1"
                     /translation="MIIDYCNNKRIKIKLKGLSPLQYKTKSFT"
     gene            complement(712..1635)
                     /locus_tag="VH800_001612"
     CDS             complement(712..1635)
                     /locus_tag="VH800_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362665.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1628..2698)
                     /locus_tag="VH800_001613"
     CDS             complement(1628..2698)
                     /locus_tag="VH800_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8362666.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2707..3633)
                     /locus_tag="VH800_001614"
     CDS             complement(2707..3633)
                     /locus_tag="VH800_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362667.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRFIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3633..5135)
                     /locus_tag="VH800_001615"
     CDS             complement(3633..5135)
                     /locus_tag="VH800_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8362668.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDSFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5200..7170)
                     /locus_tag="VH800_001616"
     CDS             complement(5200..7170)
                     /locus_tag="VH800_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8362669.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     VKQYEKAKEKWMKAKAKSNAKYAEKLADHVEK"
BASE COUNT         2261 a         1405 c         1340 g         2246 t
ORIGIN      
        1 actttttttg tactttttta tttgcccgcg ttgtaaaatg aagtgcaaca aaaaagagaa
       61 aaagccttga actacacccc aaacgttaga caaaaaaatc taacgttcgg ggtatttttt
      121 atgaaattaa gtgatgaaag tacgaaatag acatcgttaa gaaagaaaaa aatatctact
      181 atccaccaga gataaagcaa gaaataatgg ataacgtttt gatagaaggc ccgccacaat
      241 accaagtatc acttgtttat ggcttgttac atgcaggaac tctcccaagt tgaatagcac
      301 aatataagaa aaacagttat actgttgaga aaacaagagc aagaccatca caaacaggac
      361 gtaaaccaaa agaaacctga agaaatgact aaattagagc ggcttcaaga agaaaatgaa
      421 tatctcagaa ctgaggttgc ttacttaaaa aaaccgagga actccgtttg aaagaagcat
      481 ctctgcaaag aagaagacaa aaaaaccatt ataaaaaatg gacaaagacg agttctgatt
      541 agattttctt ttaagaacgg ctgtattgac tcgttctacc tactattatc atcgattatt
      601 gcaacaataa acgtatcaaa ataaaactaa aaggacttag tcctctacaa tacaaaacta
      661 aatcctttac ttaaaataga gtagccaact tttggggtca gtgcatctct tttacaattc
      721 tttttgatat ttttcaattt ctgcttggtt tgcccaaaca aagtgatttg gtttgatttc
      781 aaccattgat ggcttatcta atgtataatc atgttggtct ggatgataga caacaagttc
      841 tttttgacgc tctaaaattg gatctgggat aggcacggct gataacaaag attgggtgta
      901 gggatgaatt gggttattaa acagttcttc tgtttctgca acttctacaa taaccccttt
      961 atggataacc gcaatacgat ctgaaataaa gcgaacgact gaaagatcat gggcaatgaa
     1021 gagataagtc aaaccttttt cggcttgcat tcttttaaga agattcaaga cctgtgcgcg
     1081 aacggaaacg tccaaagctg aaatcggttc atcagcaata acgaattcag ggttcattac
     1141 tagggctcta gcgataccga tccgctgacg ttgacctcct gaaaattcat gagggtagcg
     1201 cgtcaaatgc tctgatagca aaccaacttc ggccatcatg ttcttaattt tttctttacg
     1261 ttcttcctct gttttaaaca gattaaagtt ataaagacct tctgaaatga tgtagtcaac
     1321 ggttgcccgt tcattcaaac tagcagcggg atcttggaaa atcatttgaa ttttacgaat
     1381 gagctcattg gcttctgatt ttgattttct gccattaatt actttcccat cgtataaaat
     1441 ttgacctgaa ctagtatcgt tcaaaccaat aatagcacga ccaattgttg ttttaccact
     1501 cccagattct ccaactaaag aaaaggtttc tcctttttta ataaagaaat tagcattttt
     1561 aactgcaaca aattttttct ttccttctcc gaaggaaatt tctaggtctt ttacttcgac
     1621 taatttctca gacatttcct tcctcctgtt gtgacatttt tcttaagatt ttttgatgca
     1681 aatcttgaat gacttctggt ttttgaactt ttggagcctc tgggtgtaaa agccatgttt
     1741 tggcccaatg agtctcagat acgttaatcg ccggaggtgc tttttcaaag tctaaaacca
     1801 tagcatattc tgagcgaagt gcaaaggcat ctccgataat tggtgaataa agtgatggag
     1861 gcgttcctgg aatagcgtaa agttcaccag attcatctgc caactgcggt aagctagaca
     1921 gcaaactcca tgtatagggg tgtcttggat catagaaaat ctcttcgact gttccaaatt
     1981 caacaatttc tcctgcatac atgacagcca ctttatctgc aatgcttgcc acaacaccta
     2041 aatcgtgcgt aataaagata atggtgaaat gatattctcg ttgaagcgac ttcaataact
     2101 caacgatttg agcttgaata gtcacatcaa gggctgttgt tggctcatca cagataagaa
     2161 tatctgggcg acaagctaaa gcaatagcga taacaatacg ttgacgcatt cctcctgaat
     2221 actcaaatgg gtaatcttca aagcgttttt tggcatttgg gatacccact ttattcatgt
     2281 aatcaagggc catttcttta gctttggcat gacttacttt ttggtgctta ataatcactt
     2341 ctgtgatttg gctaccgata gttttaatgg gactaagact ggtcattggg tcttggaaaa
     2401 tcgttgcgat ttttgagccg cgaatctttg cccactcttt atttgttttt aaatctgtca
     2461 attcttgccc acgatagaca attgaaccat tagcaatgcg tccattagac tccaacatcc
     2521 ctgtaaaggt ctttgttaaa acagatttac ctgagcctga ttcccctaca aaagcaagga
     2581 cttctccttc aacaagttcc agtgagacgt tacggatagc tgttaaaaca cgatcacgca
     2641 catcaaattc taccaccaca tctttggcag ttaagattac attattttct tttgtcattt
     2701 taactcctat ctatgtgaac gtgggtcact ggcatcagcc aagttttgtc cgacaatgta
     2761 tagtggtaac gatactaaaa tcaatgttac taagggaatc caaaagaggt aggcatttgt
     2821 tgttaagttg cttgaataat tagcaataaa acgtcctaaa cttggagtgg tggttggtaa
     2881 accaatccca aagaaggata agaaggcctc agaagataca taaactggta gcatttgtga
     2941 caacatagtc atgataactg aaaccaattg aggcaggagg ttcttaacag caatcttgta
     3001 cattggtgtt cccaaagttt gactagcaag gttgtattct aaatcacggt aacgcaagat
     3061 ttgaacacgg atggagtagg cgacaccaat ccatccagtg atacagaaag ctagaatcaa
     3121 attccaaaat cctgcaccta atgaataggt caaaacaatg ataataagca tagaagggat
     3181 atttgagata atgttataaa tttcaatcat aactttatca aatgctttag aaactcccca
     3241 tatggctcct aacactaccc caatggtgat attaattagt gtcgctataa ctgagattaa
     3301 aatagaatta cgtgccccat accaaacacc atcaaacaga gattgcccat ttttgtcggt
     3361 tccaaaccag tactctgcat ttggccaaat ataacgcttt gaaaagtcat tgatattact
     3421 aacgtcatta aagtcgtagt tggcaaacat tggataaata aagctcatca tcaagactgt
     3481 cactaaaatt acgagcataa agactgtaga ttttttagaa aaaaactgac gaaacactga
     3541 tttccagtaa gaataagcag gggtatcaat cacttcggag gcttcactat cgcgctcaac
     3601 aaatcgaaat ttagatttat caatcgattc cattacttac ctcctttttt tgttgacaat
     3661 ttaatacgtg gatcgacaag ggtcatgaca atatctccta gtaaaagtga aacaattgac
     3721 aagacagtga agataaaggt taatccaaca atcatagaat tgttagcaga tttaatagaa
     3781 tcaattaaca ttttacccat acccgggaag gcaaagacag tctctgttaa tgttgcacca
     3841 ccaatagcaa ggataatact tgcaggaacc cctgacacaa ttgggaccat ggcatttttg
     3901 aagagatgcc ctctgtaaat ttcagattct gataatcctt ttgaacgcgc aaaacgtacc
     3961 caatcgctgg cctgaaggtc aacaagatag cgacggaacc agataaccgt agttggaata
     4021 tttaaaattc ctaaaataag ggctggtaaa atataagatt taggatcaga tgcccccagc
     4081 attgggaaac tatctggtaa accaaccatg ccacctagga agcgaacaac atagataaca
     4141 gcaatacttg gtaaagcaag catgaaggtc atggtcgctg ttgagaaact gtcaaaatag
     4201 gtatttttaa accgagccat aaataaacca agaggcaaac caacgatata ggaaaacata
     4261 acaccaaaaa aaccaattac aaaagaattg tgaatcattg atgggtcgac ataattattg
     4321 atggttttag tgtaggaatc tcccttacca tagtttacct tggtgatatc atccaatgat
     4381 tttggatttt tgtagctacg gctatagata tccactgacg atttcttagt gacacctgat
     4441 gggaaggtca catcttgaag agctgttcgt ccttgccctt gtgaaatgac ctgaagaaca
     4501 ggaatattgc tgtatgttgg ataagatgtc cctaagttta aggtaacaaa gttttggtga
     4561 agataaggaa attttccgtt agtatagagg agatacttat gttttgtccc cgaaccaaca
     4621 agtgaccagc caactgattt atctttttct agacgaatat acctagctaa ttttggatta
     4681 tctttatcct gaatcttcca agggtgatca ataacaacta gatttgagaa aaagttccaa
     4741 acacgttcgt aaatagggat attgcgaatt gcataaaact gtttgctagt ggggaagcgt
     4801 tttagctgcc agccattgcc aagagaatca atatacttct catagatagc tttgttagca
     4861 ctagttgctt ctgtcgttac actactatct actttagaag cattatcttt taattctttg
     4921 cttgaaaaat aattgacata acccatacgt tgaaaagtta gattttcata cgctactttt
     4981 ttatctggtg ttgttgtcat tttattataa ttagggtctt gtttaaagat aaggctggta
     5041 ggtactagag tatatacgat ggtgtatgtt aaagccgtta ccagaactac cgacactaac
     5101 gatcgcatga tacggtttaa aatatatttt ttcatagttg tcctcaatag ttcaaaagaa
     5161 ctccctcaca taaacgagaa agttcttttg aacatcgttt tatttttcaa cgtgatcagc
     5221 taacttctca gcatattttg catttgactt agcctttgct ttcatccatt tttcttttgc
     5281 tttttcgtat tgttttactg tgacaggttt gtcttgaagt ttcattcctt tatatgctag
     5341 aggaccttta gaccctgccc aagagaagcc cccgctaaat ggaacggctt tagtaactcg
     5401 tggagtgcca cccaatgcca caactggaat atctacggca ttatctgtaa ggtaggcttg
     5461 tgcttttgcg taagctttat agcgcgcatc gttgtcgtct gtaattgctg ctgcttcatc
     5521 aagaagagtt tggtaggtat caaggcctgc agctgccaca acatccttat tttgacctgc
     5581 tttgattcca agtttttgga taacagatcc accacctact ggactcatga tgtcaaggta
     5641 ggtccgtgga tcttgatagt ctggtcccca ccatgatgaa atgatatcgt agtcttgttg
     5701 ttctggggtc tcagcataga agccttgggc ttcgtgagtt gatgtttctg tttcaagaac
     5761 attgacaatg acattctctt taccaagaga tgcttcaaca gattgtttga aagactgggc
     5821 ttcctgaaca gttgctgcgt ttgcttggtc aacagggtaa tctaattgaa ctgggaaggt
     5881 tacaccttca gctgttaaag cttctttggc ttttgcaaac tcagcttttg ctttttcagg
     5941 attatagaaa ccatcttgag catcagctaa gttaacgtct ttccattcat ccccaagttt
     6001 tgccatttcc ttttcaactt ctgaaccaaa atcactttct ccaatggtca caaatgttgg
     6061 tgggacaagc atgttacgta aggcttttgt tttggcatct tgacctgcag tttgtgcttg
     6121 gaatgacgct cggtcaaaag caaactgaat agcttgacga aaatccttgt tgttaagagc
     6181 tttcttaccg gcatcttgtt gtgcagggtc tttcttagtg tttttgaaag aagtacggtt
     6241 caaattccat gttaaatgac ggatatctcc agtcaacatt ccgtaagtaa tgttatcagc
     6301 atagtttttc ttagctgatt tgtaggtagg gtcatttggg taaagtcgtg caacgctgaa
     6361 ctcacccttg tcaaagttct tgtagaacga acctgggtct gaaccatctg agtaagtcaa
     6421 tttaacagat tctatcccaa cattcttagc atcccagtag ttttcatttt tatggaattc
     6481 catagatgat tttgaggtga aggcgctcaa gaagtaagca ccattaacaa ggattgatga
     6541 tggatcggtt gtaccaaaat ctttaccttt tgacttcaaa aatttcgcat taactgggaa
     6601 aagcacacta taagttgttt ttgaattcca gtagctttca ggcttgttca aagtatactg
     6661 aacagtttta tcgtcaaggg ctttgacacc aacttcttta aaatctactt caccattttg
     6721 gtaagccttt aagtttttta ttgaatcttc aacaacgtaa agagcatctg atttatcgtc
     6781 aaccgcgtgc ttcaaaccag tcacaaaatc ttctgctgtt actggggcat attcttcacc
     6841 atcagccgta taccaagaga caccatcgcg aagagtataa gtataagtca gaccgtcttt
     6901 tgaaaccttc caatctttag caagtgatgg tactaaatta ccatactcat cgttttccaa
     6961 aagaccatca accatttgtg ttatcacatc agtcgttcca ccgccattag tcaaaatata
     7021 atccaatgat tttggatcgt taacaaaaac gtacttgtag gtttttgtag cttctgagcc
     7081 acctgaagca tttttattac cacaagctgc caaagcggat actgacaaga tcgcaacact
     7141 tacagctgcc aaccatttac ttttcttcat aaaagtcacc cctaaacttt atttttcatt
     7201 ttttggcaat tgctaaatga aattggttaa ttgaagacat tatatcataa aa
//
LOCUS       DAUGJR010000058         6990 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUGJR010000058 DAUGJR010000000
VERSION     DAUGJR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6990
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.058"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(18..290)
                     /locus_tag="VH800_001617"
     CDS             complement(18..290)
                     /locus_tag="VH800_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEQ8362670.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            complement(307..1668)
                     /gene="dnaB"
                     /locus_tag="VH800_001618"
     CDS             complement(307..1668)
                     /gene="dnaB"
                     /locus_tag="VH800_001618"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEQ8362671.1"
                     /translation="MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFY
                     KYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANA
                     EYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFR
                     KISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTA
                     FVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNV
                     TIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPEN
                     RQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADI
                     VAFLYRDDYYRKECDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQF
                     EER"
     gene            complement(1704..2156)
                     /gene="rplI"
                     /locus_tag="VH800_001619"
     CDS             complement(1704..2156)
                     /gene="rplI"
                     /locus_tag="VH800_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEQ8362672.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            complement(2153..4129)
                     /locus_tag="VH800_001620"
     CDS             complement(2153..4129)
                     /locus_tag="VH800_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEQ8362673.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNGLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKCLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKYLLLKTINMTMKETGEVES"
     gene            complement(4220..6118)
                     /gene="mnmG"
                     /locus_tag="VH800_001621"
     CDS             complement(4220..6118)
                     /gene="mnmG"
                     /locus_tag="VH800_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEQ8362674.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPIKETNDRVQDLGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPTNIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            complement(6242..6559)
                     /locus_tag="VH800_001622"
     CDS             complement(6242..6559)
                     /locus_tag="VH800_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8362675.1"
                     /translation="MIVRNGKNFLTRDADDQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRAKVNQLAFMVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
BASE COUNT         2130 a         1469 c         1083 g         2308 t
ORIGIN      
        1 cctctatgag gcaaaaatca atctaaataa cgaattaatg ttttttctgt caaaatatct
       61 gaataggtgt atgattcgac ataagaatta tcaattgctc ctggagtatc agagctatca
      121 ctatactcaa tgataaagag tgaactgtaa acttcaataa gcctaccaat tttatttttt
      181 tcccgtttcc gtccattctc aagggttaat tctactaact gtccttcatg ggctcttatg
      241 tcctctttaa tttttttcat ttttgcaaca tctgtaaatg catcgctcat tttttgtctc
      301 tctttcttat ctttcttcaa actgggctat acttgagaat ttgttgtatt ctttttggaa
      361 catcagtttg actgttccac gcgccccagc tctatttttc tcgaggataa cttcaattgt
      421 gttatcttca acagcttctt cagcatcatc acattcttta cggtaataat cgtcccggta
      481 taagaaggct acaatatcgg catcctgctc aatagatcct gattcacgaa tatctgataa
      541 aactggtcgt ttatcttgcc tttgctcaac gccacgagaa agctgactta gggcaataac
      601 tggtactttc aattctttag ctaggatttt aagctgtctt gaaatatctg aaacctcttg
      661 ctgacgattt tcgggtttag ttcctgtaat caactgtaag tagtcaatta caatgagacc
      721 taaaccacca tccacttctt gagacaattt ccgtgatctt gcgcggattt cagtaatttt
      781 aatcccgggc gtatcgtcaa tataaatcgg tgcttctgcc aaagctccct gagcaattgt
      841 tacattattc caatcctgat ctgtgagttg ccctgttctt aaactgtgcg aatcaaccat
      901 tccttctgct gcaagcatac gatctactaa actttcagca cccatttcca aagaaaaaat
      961 agcaacagtc tttttttgct tagtccccac attttgcgca atattaagaa caaaggcagt
     1021 cttccccact gctggccgag cagctaaaat aactaattga tctgggtgta aacctgttgt
     1081 aatcttgtca aggtctctaa aaccagttgg taaacctgta acatttgaag tctgcttaga
     1141 acgtgcttct aaagcctcgt aattaacttt tagcacatct gaaattttgc gaaacccact
     1201 acgattacta tgttcattga gttcaattaa agctctctca actccagcga taacctcttc
     1261 tggttttaaa atttcatcat aagctaggtt gacagattct gtcaacctag caataatatc
     1321 acgcaacata gctttctcag ctacaatttt agcataatat tctgcattag cactagttgg
     1381 gacactatta actagttcaa caatatagga taagccacca atactttgca gatcatcttg
     1441 atcatctagg attgttctta tagtggttgc atcaatggca tcattacgat cgctgagggt
     1501 aatcattgcc cgaaagataa ttttatgagc gtacttataa aaatcgtctg gactgataaa
     1561 ttctctcact gcaatcagct tatcaggtga gataaagatt gacccaagaa cagattgctc
     1621 tgctagtaaa tcttggggtt gaactcgtaa ttcagctact tcaggcaact tcataacctc
     1681 caaatcttgt gatgtttttt atattatgct tctgtgatag ccaatttaat ctcagctgtt
     1741 acttccttat gtaatttcac aggaacttca attagaccaa tggcgcggat aggatgatct
     1801 aaaacaatat gacgtttatc aacttttaca ccaaattgct tttgcaattc ttctgaaatc
     1861 tttttagctg tgatggaacc aaatgtacgt ccatctggac caactttttc ttgaaattga
     1921 acacgtgttt tgtcctcatc caaaacagcc ttgacagctt gagcttctgc taatatttca
     1981 gcttgagctt tttcttcagc tttttgtttt ccttttaatt caccgatgct ttgactagtt
     2041 gcttctttag ctaaattttt cttaataagg aaattttgag catagcctgt tgggacctct
     2101 ttgatttctc cttttttacc ttttcctttt acatctgcta aaaaaataac tttcatgatt
     2161 ctacttctcc tgtttctttc attgtcatat taatagtttt caataataag tacttcgctt
     2221 ggggaagact gatatccgtt aactgacagg cagcaagatt aaagtggcct cctccaccta
     2281 atttttccat cacacgttga acattgattt tactacgact tctagctgaa atagcaatct
     2341 tatgagaagc tgtttcaact aatacaaagc tagcctcaac gtgagccatt gacagtatcg
     2401 tatctgcagc tttactagca ataacattgc tataaagatg atttttttct cctgcagcta
     2461 caatgatact gtcaccaaga cgttctcctt gtaaaataat ttcatttatt tgcttatatt
     2521 cttcaaaatc tgttgcggat atattttgaa tttcaacact atcacttcct ttgcttctta
     2581 agtaactagc gacatcaaag gtacgacttg tcactcgcgt agaaaaattt ttagtatcaa
     2641 gcataatacc tgccattaaa acactggctt ggatcttatt taaacatttt ttagcatttt
     2701 gaaattgaat taactcagtg acgagctccg cagcactact tgctccactt tcaataaaag
     2761 ttaagatagc attatcagga aaatcatcat ctcttctgtg atgatcaact acaataacat
     2821 tttgaaactg ttcataaaat tctttagaaa gtgttaaaga tatcttagaa tggtcaacca
     2881 ttactaaaag tgatcttgga gtcactaaac ccattgcttg agaaacactg attagacgag
     2941 tctttccgtc agcctgcaat cgctcaatag ccctttcaat atctggactc atctcatctg
     3001 gattgtaaac ggcaaaacta ttttcaataa tgttacctgc gaaaaattgc ataccaacag
     3061 ctgaacctag tgcatccata tcaagtttcc tatgtccaac aataaaaaca ttgtccacca
     3121 tcttgattcg atctgaaata gctgtcatca tagcacgggt acgtgttctt gaacgtttaa
     3181 ctgtagaaac agaccctccc ccgaaataaa ttggattcgt atgatccgca ttttcacgaa
     3241 tgacaatctg atcaccacca cgaacaagcg caatattaag attctcaaga gctacctgtc
     3301 caatctggct atgattttct tcaccaaaag aaattcctat gctgagtgtt aaagggcgct
     3361 gagcatcttg agcttcttta cgaaactctt ctaagacaga aaatttatta tccatcaaat
     3421 catttaatgt tttaaagtct gtaaagaaat agtagcgatc catattaaca cgacggtaaa
     3481 aaatccgttt tgactccata aactcatcaa tgaagttagc tacaaatgaa ttaatttttg
     3541 aggtatctgc atctgataaa tcatcagtga tatcatcata attatcaacc gaaataatgc
     3601 caacaaccgg tcttaacata ctagcatcag ctaattgcct gtttcccaca aagctatcaa
     3661 aaaaataaaa aattcctgat gatacatcaa tataagaagt gtatttatta ccagaaactt
     3721 caaatgtttg agaaatatct tcacgacgtt tttccgtaat aatttgctga atcaaaccgt
     3781 tttgtataaa accctcttca gttgtaaaaa ttaattctgc ataaggatta taccattcta
     3841 cagcgttggt ctcttgatca aattgaacta ctccaacagg catattatca agtagcgttt
     3901 ttaggttatc ttctgtttgt tcatttaaga gctcaatatg agctaagtct gataattgat
     3961 aagcttcttt ttgataccat aaaagagcaa caacaaatag caaaacgaga aaaatagcta
     4021 ataatattaa tatttttgat tgcataatac tgacacaaag tgccagcagt ccaaataaaa
     4081 tcaatcccat cataatcaaa tgaatggttt caaaacgaaa ttttttcatc tttataacct
     4141 cttaagcaca cattatacca taaaaaagcc ctgaaataca gagcttccac ttgctttgag
     4201 attacaattt catttccatt taatattttc gatgagcttt tccgtttcct tctaaataaa
     4261 tcatcaagat actgatgtcc gcaggattga ctcctgaaat acgactagct tgtccaattg
     4321 tttcaggatt aattttctta aatttctgac gcgcctcagt tgcaatagaa tcaatagcat
     4381 cccaatcaat atttgtagga atacgttttt cttccatgcg tttcatctta gcaacctgat
     4441 ctaaagcttt gcgaatatag ccttcgtact tgatttctgt ttctaaaagt tcaatgattt
     4501 tagcatctaa atcttcagcc gcaggaccaa caaaagagac tgcagtcgca taatcaattt
     4561 ctggacgacg catgaattct ttagcagtca tcgcatcggt taacggtttg aagcctagat
     4621 cttgaacgcg gtcattggtt tctttaatcg gttttaattt gatactgttc agacgtttta
     4681 attcgttatc aaattggttt ttcttaattt cgaaggcctt ccaacgctca tcatcaacca
     4741 acccaatgtc gcgaccaatc tctgtcaaac gcatatcagc gttgtcatga cgtaaaatca
     4801 aacgatactc agctcgcgat gtcaacaagc gataaggttc caaggttcct ttggtaacca
     4861 aatcgtcaat cataacgcca atataggcat cgctccgttt caaaataagt tctggcttac
     4921 cttgaacttt caaagcagca ttgattccag caataagtcc ttggccagca gcctcttcat
     4981 acccagaagt tccattagtt tgcccagccg taaagagtcc tgaaattagc ttggtttcaa
     5041 gtgtggcacg tagctggtga ggtaaaacaa tatcatattc aatagcataa ccagtgcgca
     5101 tcatttcagc cttttcaagt cctttgatcg aatgaatcaa atctttttgg acatcttctg
     5161 gaagactcgt tgacaaccct tgaacataca cttcttctgt atcacgcccc tctggctcta
     5221 agaaaagttg atgacgttct ttatcagcaa agcgaacaat cttatcttca atagatgggc
     5281 agtaacgagg gcctacacct ttaacaatgc cagaaaacat cggtgctctg taaaggttct
     5341 gattaatgat atcatgacta gtttgattcg tataagtcaa ccagcaggga atttgatctt
     5401 tgagataatc agcatctttt gacataaatg aaaaatgatt aggtttgtca tcacctggct
     5461 gaatttccgt ttgatcgtaa ttaatagaag atgctttgac acgaggaggc gttcctgttt
     5521 tgaatctgcc aatttctaag ccgagttttt ttaaattatc tgctaaggtt actgatgcca
     5581 aactattatt aggcccagaa gaatatttga gttctcctaa aataatttcg ccacgcagag
     5641 ctgttcctgt tgtcactaca actgccttag ctgcaaattt ttgtcctgtg gctgttaaaa
     5701 cacctacaac tcgtccatct tcaactagaa tatcatcaat catcgtttgg cgaagagtca
     5761 aattagcctg tttttcaacc gtatgtttca tttcacgcgc atacagggat ttatctgctt
     5821 gagctcggag agcgcgtaca gctggtccct tacctgtatt aagcattttc atctggatat
     5881 aagttttatc aatattttta cccatttcgc cgccaagagc atcaatctct ctaaccacta
     5941 tccctttggc agatcctcca atagaaggat tacacggcat aaaagccaac atatcaaggt
     6001 tgattgttgc caataaagtt ttacaaccca tacgactagt ggccaaactg gcttcaacac
     6061 cagcatgacc tgcacctatg acaatgacgt catagctttc tgtaaattca tgtgtcattt
     6121 ttttaaaatc ctttatttca gtctattcat ttaaaatcat acgctttagt ttagccttca
     6181 atacggacaa tatgtcctgg ccatttagcc aactcggttt gtaaaaactc aggaacaaga
     6241 ttcatttgat ccagttgatt gattggaatc cattcacaaa cctgtcgctt gcattctcta
     6301 tcatttctag tttagggtct tctaaggggc ttaccaaata atgaaattca atattatgcc
     6361 agaaaacatc atcgatatca aaatgattct caaccataaa agccagttga ttaaccttag
     6421 ctcgaatacc aacttcctct aaggtttcac gtaaaacagt ttcatgcgtt ttttcaccta
     6481 ccaaacttgt accaccaatg gtgtaatatt ggtcatctgc atctctagtt aaaaaattct
     6541 taccatttct aacaatcaag cactagctcg taaactaaag ttatctgacc tctagtgatt
     6601 ctaaattcca gtcctattag ccatctcatt tctagagcta aaccataaaa agggccaaaa
     6661 ccctagaaga ttgcaggaca aaaaaaccta caactttcat gagctttgac catcattccg
     6721 gttgttacta tctattttaa aaaaaatgat tagtgattgt caatattgat ttcatcacag
     6781 acctttacag taatgtcaat gtttttacaa ctctgtcaat ctattgtaat gtttttaaaa
     6841 tgattacaaa agtatcacta tgtctaatct agcgaggcga gaaataaaaa tgtcatcagt
     6901 attatcatac gattttttga tatcttctaa agtagtaaaa tacagatact gttgtttcta
     6961 agtctacaag taagaacgcc gataacaaaa
//
LOCUS       DAUGJR010000059         6870 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUGJR010000059 DAUGJR010000000
VERSION     DAUGJR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6870
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.059"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            172..945
                     /gene="cfa"
                     /locus_tag="VH800_001623"
     CDS             172..945
                     /gene="cfa"
                     /locus_tag="VH800_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEQ8362676.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NFQRDALVQKLDEGHQQLEAIKHEAKGTDIETTVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQDALETALKS"
     gene            complement(1314..2549)
                     /locus_tag="VH800_001624"
     CDS             complement(1314..2549)
                     /locus_tag="VH800_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEQ8362677.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQ
                     ITPIAKKQLHHTHYRIVKM"
     gene            complement(2669..3991)
                     /locus_tag="VH800_001625"
     CDS             complement(2669..3991)
                     /locus_tag="VH800_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEQ8362678.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSHLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(4119..4205)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            4520..6838
                     /gene="pcrA"
                     /locus_tag="VH800_001626"
     CDS             4520..6838
                     /gene="pcrA"
                     /locus_tag="VH800_001626"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEQ8362679.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
BASE COUNT         2305 a         1281 c         1347 g         1937 t
ORIGIN      
        1 tttaatgaca ttaaaaaatg attatttttg cgaaattctc ttattttctg gaaattaaag
       61 aaatattgac cttagtaaaa acaagtagta tgataacgtt ataagcgctt ataaattaat
      121 ttaacttcac ttaactattt aaatagattt attatattca ggaggaataa tatgaaaccc
      181 aaacaccttc tctgtctttc aacagttgtt gctggattag ctttattttc aactatgacg
      241 cactcagttt tagctgatga tgcttcaaat cccgatacta ttttaatgaa taacaaccaa
      301 gcaaattttc aaagagatgc tctagtgcaa aagcttgatg agggacatca acaattagaa
      361 gctattaaac atgaagctaa aggtactgat attgagacta ctgttaacaa agctatcgat
      421 gctgttgatc acatgaagag ttctatacgc ttcaatactg aaacgatcta tgattttagt
      481 tcaattgggg caagagtaga agcattatca gatgctatca aagcaatcgt attttccaca
      541 acccaattaa ctcataaagt agaaaaagcg catactgata tggggtttgc tattactaaa
      601 ttagtcattc gtattataga tccatttgca tctgttgacg ctatcaaagc tcaagtacaa
      661 gaaattaaag cacttgagga aaaagttatc aattatcctg atttacagcc aacagaccgt
      721 gctactatct atactaaagc taaactaaat aaagctattt ggaacactcg tttagaaaga
      781 gataaaaagg ttttgggaat caaaccattt gacgtttaca atagacttaa caaagctatc
      841 acacatgcgg ttggtgtcca actaaatccg acaaccactg ttcaacaagt tgacgatgaa
      901 gttattgctg tgcaagatgc tttggaaaca gctcttaagt catagagtgt ataagtaatg
      961 tgttgtatag gtagatgatt acattaggat atagaatagg taaagatttt aaatatctta
     1021 ccattgtaga gtttgaggtg atgttctcat aaacaatgag tcacctgtag ccctttttgc
     1081 ctttaacatg atgtaccaat ttaaggtatt gttcaaccgt cactattgaa tcttgtttaa
     1141 ccccctaaac taataagatt caatatgaaa acgtgtattc ttaaaaaaat ccctatgatc
     1201 tgtttaaaaa caaattgtag ggatttttta actatttcac ttatcatttt gggactagga
     1261 atcgctttag gaatatcatg aagtatagtt atgttataag agaagtgatg tttttacatt
     1321 tttacaatac gatagtgtgt gtgatgtaat tgtttcttag cgataggggt aatttggtgg
     1381 aagagtaagg accaagattc atgacgcctc caaatactgg tacgttgatt gccatttaat
     1441 tggtaagtta ccaacatcgt tttttgacta atggattcaa tctgaaaatg gttgaagtta
     1501 cttggataat aaatttcttg gttcaaaaat tgttcatagt taactgtttg gccattcgca
     1561 tcaatcagtt ggaaagactt agcaatgtag tggtcatagt caggaacctt actcaaaatt
     1621 aatttttcgt agcggtagag ctttttggcg acattatcaa aaatctcttc ttcgggaatc
     1681 atggcaggct caacgtgaat gtcaatgtca taaatagaaa attggtcact caataactgc
     1741 tccactttct ctgtaataga gtgactttca tagactgaaa gatcaggatt catttcaagt
     1801 acaatatcaa gatagacatt gctaccatag gtcctagctc gttgagactt aacggcgaca
     1861 attttaggga tttctaaaat ggctttttcg tattttttca aatgacggct atcaaatcca
     1921 tcagataaac taaacgaact ttccataaag atatcaaaag ctgttttaag aataaagaac
     1981 gtaatgatca tagcagctat atgatcgata actggtaaat gcaaagaagc tgctataata
     2041 gcaattgatg ttccgataga agtaacagca tcagctagat tatccttaga agcagcgact
     2101 aaggcactgg attttacacg tttggaaaga cgtttgttaa agacataaac ccctaacata
     2161 acaaaagctg aaacgatacc gacaatagcc ccaagagggt caatatcaac ttgctgacca
     2221 ctaaagatac ttttaattgt gtgaatcagt acttggaaac ctacaagaaa cataataaaa
     2281 gaagtgacaa ggctggataa gtcttcaatt ttccaatgac caaatttatg attggcatcg
     2341 gctggttggc tagctaagtg aagaccaata agcagggcta catttcccac aatatccgat
     2401 aaattgttaa atccatcagc aataagggaa cttgcattta acaaataacc agctaataat
     2461 ttggcaacac taagcgacaa gtagacaata atactaacga ttgggccctt tctggctagt
     2521 tttaaatttg caatcggatc ctgtgtcata ataactcctt tgatttcaac tttatattat
     2581 accataaaaa ggggcttaag aaaaaagcct agcgtcttga acttggcaga agaagactag
     2641 gtataactgg gtagtactaa cgtcatgttt acttaataaa gtaatgcttg gtttctaaaa
     2701 taacaactgg cgagagagct aggagggcaa tcaggttagg aagtgccatt aaaccattga
     2761 caatatcagc caaaacccaa attagttcta acttaaggaa gcctcctagg cctaccatta
     2821 agataaagac aatacggaag taggtgagat gtgtaatgcc aaagaggaat tcaaagcagc
     2881 gttctccata ataactccat cctaaaatcg ttgtaaaggc gaagagaact agggaaaagg
     2941 ttaggccaaa agtccctaaa tttccaaaca cagtggcaaa ggcagattgg gtcagaggag
     3001 ccccttcgag ctgcccagtc cattggcctg ttactaaaat agataggccg gttagggtac
     3061 agataataat cgtatcaata aaagttcctg tcatggagat cagtccctgc tccacgggtt
     3121 cattggtttt agctgctgct gcagcaatag gtgcagatcc tagtccagac tcattggaga
     3181 agacaccgcg tgcaattcct ttttgaatgg catccttcat gagacttcca gcaaagcctc
     3241 caatagcagc tgtcggagtg aaggctgatt gaaagactaa acgaataaca ggaagtagct
     3301 gttggtagtg actaaaaata actgctaaac tagatagaat ataaaaaata gccataaaag
     3361 gaacgacttt ttcagccact ttggaaatgg aatgaatgcc accaaaaata atggcagcca
     3421 caaagatagc taaaacaata ctgaccattt gtggggataa gccaaagcta tgacctaaag
     3481 acgaggtgat cgagttcact tgagcaaagg ttcctattcc aaatagggca actaggatcc
     3541 ctgaacccgc aaaaagaatg gctaagggtt tccattttgt ccccatgcca ttaacaatat
     3601 agtacatagg accaccagaa atatgaccgt tggcatcctt tgtacggtat ttaatcgcta
     3661 gtaccccttc agcgtactta gtggccattc caaaaaaagc ggcaacccac atccaaaaga
     3721 gcgctccagg accaccagac ttgatagcag tggcaacccc aacaatgtta ccagttccga
     3781 cagtagcggc aagggcagtt gcaagagcag caaaggatga aatatctcca tgtccttcgt
     3841 catctgaaaa aatgagttta aaggctcttg gtagttttaa gatttgaatt aatcctaaat
     3901 gactggtaag gtaaatcccc gtcccaacca ataaaattaa gaggggcggt ccccaaacaa
     3961 ggttatcaat taatttaacg agtgctatca tctttctctc ctaaaagtca tcgaagacgc
     4021 caaaagaaaa aagctatctc tttctttgag acaacttctg aagcaatgat aaaacagcaa
     4081 acacaaaaaa gactaagact gttcttaatg gtgtttgtat tttaccttct gtccttttgc
     4141 ctgagagatt gagcagtatg ccttgcccct tcggcgccta ataaggtctc tccagaagtc
     4201 cgtccatcaa acagtcccgt tcaaaaactg aacacctgag agtataactc cttcggcgaa
     4261 aaaaattctt ctcctgcatg acatcattcg gtttattaaa ttaggactat catacctcaa
     4321 aaaacgaatg aagtcaacca aaatagcaaa aaaataagga atgctttaag aaatcgctat
     4381 tatttttaaa tatctgatcc taaactagaa aaaaggaatc tctttacttt tggggtcttc
     4441 tttgctattt ttcttggaaa catgatataa ttttaaggtt gataaaagag atgtcactga
     4501 acgagattaa ggagaaagca tgaatccttt attaaatgga atgaatgatc ggcaggcaca
     4561 agctgttcaa acaactgaag gccccttatt gattatggcg ggggctggtt ctggtaaaac
     4621 aagggtactg acccatcgta ttgcctattt aattgatgaa aaatttgtca atccttggaa
     4681 tattttagct attaccttta ctaataaggc tgcgcgtgaa atgaaagaaa gggccttggc
     4741 cttaaatcca gctactaaag ataccttaat tgctaccttt cactccatgt gtgtacggat
     4801 tctgcgtcgt gaggctgatc acattggtta caaccgaaac ttcacaatcg tggatccagg
     4861 tgagcaacga acgttgatga agcgcatttt aaaacaatta aatatagacc ctaaaaagtg
     4921 gaatgaacgt tctattttag gaactatttc aaacgctaaa aatgatttgc ttgatgaaaa
     4981 gggatacgag gcacaggctg ctgatatgta tagtcaaatc gtagcgaggt gttacaaagc
     5041 ttatcaggaa gaattacgac gtagcgaagc acttgacttt gatgatttaa tcatgatgac
     5101 gctacgcctg tttgacgcta atcctgacgt gttagcttat taccagcagc gttaccaata
     5161 cattcatgtg gatgagtacc aagataccaa ccatgctcaa tatcagctaa ttaaattact
     5221 agcttctcgc tttaaaaata tttgcgttgt tggagacgct gatcagtcta tctatggttg
     5281 gcggggagct gacatgcaaa atattcttga ttttgaaaaa gattacccag atgctaaggt
     5341 agtgctttta gaagaaaact atcgctctac caagaaaatt ctgcaagcag ctaacgacgt
     5401 gattaacaat aaccgtaatc gccgtcctaa gaaactttgg acacaaaatg cggatggtga
     5461 acaactggtt tattaccggg caaatgatga gcgagatgag gcagtatttg tggcctcaac
     5521 cattagcaat atgagtcaag agcttggaaa aaacttcaaa gatttcgctg ttttataccg
     5581 taccaatgcc caatctcgga ccattgaaga agcactctta aaatccaata ttccttacac
     5641 catggttgga ggcaccaagt tttacagccg taaagaaatt cgggatttga ttgcctattt
     5701 aaccattgtt gctaaccctg ctgataatat ttcttttgag cggattgtga atgagcctaa
     5761 acgaggtgtt ggtccaggaa cgcttgataa actgcgtcag tttgcctatg agagtgacca
     5821 gtctttatta gaagcagctt caaatctatt gatgtccccc ttgaaaggta aagcagcaca
     5881 agctatcatg gacttggcca atattctcgg tcagctacgt caagacctag atcagatgag
     5941 tatcaccgac ttagcagaag ctttgttaga aaaaacaggt tatttagata gcttacgcct
     6001 gcaaaataca ttggaaagcc aagcccgtat cgaaaatatc gaagaattct tatctgttac
     6061 caaaaatttt gacgagtcaa gtgcctctca agaagaagac gaaaccggtg ttgatcgctt
     6121 gggacgtttt ttaaacgatt tagcactgat tgctgataca gatgattccc aagcagaagc
     6181 tgctgaagta accttaatga ccctacatgc tgccaaaggc ttggagttcc ctgttgtttt
     6241 cttaattggt atggaagaag gtgtcttccc cttatcacgt gcctctgaag atccagatga
     6301 attggaagaa gaaagacgtt tagcttatgt cggaatcaca agagctgaag aagttctctt
     6361 tatgaccaat gccaacacca gaaccctctt tggtaaaagt agttataacc gtccaacacg
     6421 cttcttgaaa gaaatttcag aggaactact ctcttataaa ggattggcaa gaccagcaca
     6481 atcttcattt ggtgtgcgtt tttctactga aacacacaca cagtttggac aagggatgag
     6541 cctatcagaa gccttacaag ctcgaaaggc ccaggctcaa gtaagacaat cagcacagcc
     6601 aatgcaggca catacgatac catcagcttc aactagctca gttttaccgt ttggttctaa
     6661 tagctctgta gaagaggtca cttggcagat tggcgatatc gctcaccata aaaaatgggg
     6721 agacgggact gtgcttgagg tttcaggctc cggaaaaacg atggaattga aaatcaaatt
     6781 tccagaagtt ggtttaaaga aattactagc aagtgttgct cctattgaga aaaaataaga
     6841 aaaaaatgag cttcctacta tataagtgag
//
LOCUS       DAUGJR010000060         6506 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUGJR010000060 DAUGJR010000000
VERSION     DAUGJR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6506
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.060"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            79..444
                     /locus_tag="VH800_001627"
     CDS             79..444
                     /locus_tag="VH800_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8362680.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            444..2108
                     /locus_tag="VH800_001628"
     CDS             444..2108
                     /locus_tag="VH800_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEQ8362681.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            2345..3235
                     /locus_tag="VH800_001629"
     CDS             2345..3235
                     /locus_tag="VH800_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEQ8362682.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHIRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            3465..4319
                     /locus_tag="VH800_001630"
     CDS             3465..4319
                     /locus_tag="VH800_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEQ8362683.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNLKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            4512..5708
                     /locus_tag="VH800_001631"
     CDS             4512..5708
                     /locus_tag="VH800_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEQ8362684.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            5971..>6506
                     /locus_tag="VH800_001632"
     CDS             5971..>6506
                     /locus_tag="VH800_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8362685.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKK"
BASE COUNT         2104 a         1056 c         1383 g         1963 t
ORIGIN      
        1 gttagctatt ctatctcttt tacattactt ctaaaatatg ataaaatagg atgataaaaa
       61 ctttttgagg tagtaactat gactgtaaaa attaatacaa aagatggtct aatcgagcta
      121 tccgacgatg tgattgcaac tgtcgtggga ggatcagcaa cggaaatttt tggtgttgtt
      181 ggaatggcca gcaaaagtgc aataaaagac aattttcaat cactacttcg caaagaaaac
      241 tacgctaagg gtgttgtagt aaaatcaaca gatctgggta tttctgttga tgtctacact
      301 gtgatgagtt atggtgtgaa aatcagtgaa gtctctaaaa atatccaaga acgcgtgaaa
      361 tttaaccttg aaagtcagct tggtctcact gctgatatgg ttaatgttta cgtgcaaaat
      421 attaaggttg taggagaaaa ttagtgtcaa atattacaac aagcttattc caagaaatgg
      481 tccaagcggc agcgactcgc cttggcaaac aagcagaata tgttaattcc ttaaatgttt
      541 ttcctgttcc agatggtgat acaggaacaa acatgagcat gactatggac aatggtgcca
      601 aggaagttgc tgataaacct gcgtcaactg tgggagaagt tggacaaatg ttatcaaaag
      661 gtcttttgat gggagcgcgt ggaaattctg gagttattac ttcacaactt tttcgtggtt
      721 ttggtcaaag cattaaggga aaagatgagc tgacaggtaa agatttggca caagcctttc
      781 aagtgggtgt agaagttgcc tacaaagcag tgatgaaacc tgttgaagga acaattttaa
      841 ctgtttctcg gggtgcagcg actgctgcct taaaaaaagc agatcttaca gacgacgccg
      901 tggaagtcat gcaagctgct ttagacggtg ccaaaggtgc ccttgctaag acacctgatt
      961 tattaccagt ccttaaagaa gttggtgtgg ttgattcagg cggtcaaggt cttgtcttta
     1021 tctatgaagg tttcctatct gctttgaatg gcgactatgt gacttcagca gactttaaag
     1081 cgactcctgc taacatgtct gaaatgatta atgctgagca tcacaaatcc gttgttggtc
     1141 atgtggctac tgaagacatt acctacggtt attgtactga aatcatggtt gcccttaaac
     1201 aaggcccaac ctatgtgaaa gaattcaact atgatgagtt tcaaggctac cttagtggcc
     1261 ttggtgactc gctgttagtg gtcaatgatg atgagattgt taaagttcac gtccatactg
     1321 aagaccccgg acttgtgatg caagaaggtc ttaaatatgg ttcgctcatc aagattaaag
     1381 tggacaatat gcgtaaccag catgaagcac aggttcaaaa gactgatgtc gaaaaaaaca
     1441 aggctgaagt aaaagacttt ggcttgattg cagtagtagc tggagaaggt ttatctgaaa
     1501 ttttcaaggc gcaaggtgtt gattacgtga tttctggtgg tcaaaccatg aatccatcta
     1561 cagaagatat tgttaaagct attgaagcag ttaatgccaa acaagtcatt atcttgccaa
     1621 acaataaaaa tatctttatg gctgcccaat ctgctgcaga agtggtggat attccggctg
     1681 ctgttgttgc aacacgtact gttccgcaag gatttaccag cttgttggcc tttgatcctt
     1741 caaaatcttt agaggacaat gtagcagata tgtcaactag tctttctgac gtggtcagtg
     1801 gaagcgttac tttggcagtc cgtgacacca ccattgatgg tttagaaatc catgaaaatg
     1861 atttcttggg aatggttgat ggtaaaatca tcgtttcaaa cccagacatg gaagcaactc
     1921 taaaagctgc ctttgaaaag atgattgacg aagatagcga gattgtgact atctttgttg
     1981 gtgaagaagg tgatcaagac ttagcagaag aacttgctgg gtatttagga gagacttacg
     2041 aagatgtgga agttgagatc catcaaggag atcagcctgt ttacccatat ctcatgagtg
     2101 tagaataata gaatataata aaaaaagagg agttaggcaa aggtctgact ctttttgtct
     2161 atattgatgt cgtaatgagt ggttttagtg atggtaagcc cctaaaaaat gagggtaatc
     2221 catcacaaag ctaatggtta cgatttaatt tgacaaaacc tagaaaaaca ttataattgt
     2281 attataacaa taagtcaaga actgaaaacg gttcagttct aagatatgac aaggaggaga
     2341 ttttatgtta ggaccattta tctttattgc ttttggggtt attgtaatcc tagctattgt
     2401 tgccagtacc ctttatgttg ttcgtcaaca atctgttgcc atcgtggaac gttttggtag
     2461 ataccaaaaa acagccacga gtggtattca tatccgactt ccgtttggga ttgacaaaat
     2521 tgctgcgcgt gtgcagctgc gtcttttaca gtcagaaatc atcgttgaaa ccaaaaccaa
     2581 ggacaatgtg tttgtaactt tgaatgttgc cactcagtat cgtgttaacg aacaaaatgt
     2641 aacagatgct tactacaaat taatgaaacc tgaatctcaa atcaagtctt atattgaaga
     2701 tgccttgcgg tcatccgtgc cgaagttgac cttagacgaa ttgtttgaga aaaaagatga
     2761 aattgccttg gaagtacaac atcaagtggc agaagaaatg tcaacctatg gatatattat
     2821 tgtcaaaacc ttgattacca aggtggagcc tgatgctgaa gtcaaacagt caatgaatga
     2881 aatcaatgcg gctcaacgca aacgtgtagc tgctcaagag ttggcaaacg cagataaaat
     2941 taaaattgtg acagcagcag aagcagaggc tgaaaaagat cgattgcacg gggtagggat
     3001 tgcccaacag cgtaaggcca ttgtggatgg tttggcggag tctattcaag agcttaaaga
     3061 agcgaatatt tccttaaacg aagaacaaat catgtccatt ttgttgacca accaatacct
     3121 ggataccctc aatacctttg cggcaaaagg aaaccaaacc ctttttctac caaatacacc
     3181 aagtggggta gaggatatcc gtacacaagt tttatctgcc cttaaaacaa aataacgtgt
     3241 aaaagcttgg ctaaaaagtt gctcaatact ggatttagca gaaggctatc ataccttgtg
     3301 aagtggcaaa cgacgaaatg aatacattac ttttattgga gaaatgaaag taaaaaaagc
     3361 ctttttcatg attaacaaca tagtattgat taaatgttaa gttgtattga cttttaaatt
     3421 aaataagttt aaaatcaact taataagcaa aaaggagatt ttcaatgaaa tccaaaaaag
     3481 ttgttagtgt tatatcactt accttatccc tttttttggt gacaggttgt gctaaagttg
     3541 ataacaacaa atcagttaat cttaagcctg ctactaaaca aacctataat agctatagtg
     3601 atgaccaatt aagatcgcgt gaaaatacca tgtctgtttt atggtaccag cgagctgcgg
     3661 aaactcaagc gctttattta caggggtatc agttagcaac ggatcgctta aaagaacaac
     3721 tcaataaacc aacggataaa ccttattcaa ttgtattaga tattgacgaa acagttcttg
     3781 ataatagccc ttatcaagct aaaaatgttt tggaaggaac aggatttaca cctgaaagct
     3841 gggattattg ggtacaaaag aaagaagcaa aaccggttgc tggtgctaaa gactttttgc
     3901 aatttgcaga ccaaaatggt gttcaaattt actacatttc agacagatca actactcaag
     3961 tagatgctac aatggaaaat ctccaaaaag aaggtattcc agtacaaggt cgtgatcatc
     4021 ttctattctt agaaaaaggc gtaaaatcaa aggagagtcg tcgtcaaaag gtcaaagaaa
     4081 caactaatgt aacgatgcta tttggtgata atcttctaga ttttgctgat ttttcaaaaa
     4141 aatctcaaga agatagaaca gctttattat cagatttaca agaagagttt ggaagacgct
     4201 ttatcatttt ccctaatcct atgtatggtt catgggaagg tgccatttat aaaggtgaaa
     4261 agctggatgt gcttaagcaa ctagaggaac gccgtaaaag tttaaaaagc tttaaataaa
     4321 gtaattgaaa aagaggtgca aaagaaaatg taacctcttt ttaagtacta ttattttctg
     4381 aaaatagggt taatgactga aaaaaatgtt gattttgtga aatgattatt ttattatttt
     4441 catattttat ctttatgcta ggaattgtgg tataatggag gagtataaaa aatattaagg
     4501 agtctattca catggctaaa ttgactgtta aagacgttga tttgaaaggt aaaaaagtcc
     4561 tcgttcgtgt tgactttaat gtgcctttga aagacggcgt tatcactaac gacaaccgta
     4621 tcactgcggc tcttccaaca atcaagtata tcatcgaaca aggtggtcgt gctatcctct
     4681 tctctcacct tggacgtgtt aaagaagaag ctgacaaaga aggaaaatca cttgcaccgg
     4741 tagctgctga tttagctgct aaacttggtc aagatgttgt attcccaggt gttactcgtg
     4801 gttcaaaatt agaagaagca atcaatgctt tggaagatgg acaagttctt ttggttgaaa
     4861 acactcgttt tgaagatgtt gacggtaaga aagaatctaa gaatgacgaa gaacttggta
     4921 aatactgggc ttcacttgga gatggaatct tcgttaacga tgcatttggt acagcacacc
     4981 gtgctcacgc atcaaacgta ggtatttcag caaacgttga aaaagctgta gctggtttcc
     5041 ttcttgaaaa cgaaattgct tacatccaag aagcagttga aactccagaa cgtccattcg
     5101 tagctattct tggtggatca aaagtttctg ataagattgg tgttatcgaa aatcttcttg
     5161 aaaaagctga taaagttctt atcggtggtg gtatgactta cacattctac aaagctcaag
     5221 gtatcgaaat cggtaactca cttgtagaag aagacaaatt ggatgttgct aaagacctcc
     5281 ttgaaaaatc aaatggtaaa ttgatcttgc cagttgactc gaaagaagca aacgcatttg
     5341 ctggttacac tgaagttcgc gacactgaag gtgaagcagt ttcagaaggc ttccttggtc
     5401 ttgacatcgg tcctaaatca atcgctgagt ttgaccaagc acttactggt gctaaaacag
     5461 ttgtttggaa tggtccaatg ggtgtctttg aaaaccctga cttccaagct ggtacaatcg
     5521 gtgtcatgga cgctatcgtt aaacaaccag gcgttaaatc catcatcggt ggtggtgatt
     5581 cagcagctgc tgctatcaac cttggccgtg ctgacaaatt ctcatggatc agtactggcg
     5641 gaggcgctag catggaactt ctcgagggta aagtattacc aggtttggca gcattgactg
     5701 aaaaataata gtcattataa tatatagtaa agggcatgct gatgcatgtc tttttttagt
     5761 tgatcatgta gagttattga actttcccta acttcactta tcatttacta gtttttagat
     5821 atagtggtat ttggctgaca ctgcattttt caaaagttta tgacgatttc atatcaattg
     5881 gtttataaaa gatatcctaa tcataaataa aacgtttacc aaaagggttt tatggattga
     5941 tatgttaaaa tagatagtga agggataggt atgaaaacgt taagaaaatt attatctaat
     6001 tacaagtttg atattaaaaa gtttaaattg ggaatgagaa cattgaaaac aggcttatcg
     6061 gtctttttag ttttattggt ttttcattta tttggttgga aagggctcca aattggtgct
     6121 ctaactgctg tatttagttt aagagaagac tttgataaaa gcgtgcactt tggcttttct
     6181 agaattattg gtaatagtat aggtggccta ctctccttag tattttttgc attcaatgag
     6241 atatttcatc aagctttttg ggttacttta ttaattgttc ctatttgtac catgttatgt
     6301 atcatggtta atgttgcatg taataataaa tcaggtatta ttggggcagt ggctgctctt
     6361 ttgattatta cactgtctat tccaacagga caaacgttta tttatgtgac ttcgcgggta
     6421 tttgaaacat tttgtggcgt ctttgtagct attttagtta atactgatgt tgaacttatt
     6481 aaaaataaat ggtttaacaa aaaaca
//
LOCUS       DAUGJR010000061         6251 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUGJR010000061 DAUGJR010000000
VERSION     DAUGJR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6251
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.061"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..198
                     /locus_tag="VH800_001633"
     CDS             <1..198
                     /locus_tag="VH800_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEQ8362686.1"
                     /translation="PDNGMMESFFGILKSEMFYGLETTYQSLDKLEEAITDYIFYYNN
                     KRIKAKLKGFSPVQYRTKSFQ"
     gene            complement(498..1370)
                     /locus_tag="VH800_001634"
     CDS             complement(498..1370)
                     /locus_tag="VH800_001634"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEQ8362687.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1594..2904
                     /locus_tag="VH800_001635"
     CDS             1594..2904
                     /locus_tag="VH800_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEQ8362688.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KALLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPDALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHSLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPILS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            2982..4132
                     /locus_tag="VH800_001636"
                     /pseudo
     CDS             2982..4132
                     /locus_tag="VH800_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4259..4414
                     /locus_tag="VH800_001637"
                     /pseudo
     CDS             4259..4414
                     /locus_tag="VH800_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039767.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4461..4991)
                     /locus_tag="VH800_001638"
     CDS             complement(4461..4991)
                     /locus_tag="VH800_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEQ8362689.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(4984..>6251)
                     /locus_tag="VH800_001639"
     CDS             complement(4984..>6251)
                     /locus_tag="VH800_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HEQ8362690.1"
                     /translation="FPIVYISFSGGKDSGLLLNILLDFRDKYYPDREIGVFHQDFEAQ
                     YSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTALSSYEMFWYPWDDKTEDIWVRPM
                     PSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYKQIHGNQKTVCILGNRASESLHRY
                     SGFINKKYGYQKECWITKQFKDVWTASPLYDWSVEDIWHAYYKFSYSYNELYDLFYKA
                     GLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKLLGRVQGVNFSNIYGRTKAMGYKS
                     IALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKSIDFWHKTGGGLAEETINELIEKG
                     YRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTTKDIPSWKRMCFCILKNDHICRTM
                     GFGLTREQQKIVAFLKEKYKTSLKELESE"
BASE COUNT         1938 a         1340 c         1013 g         1960 t
ORIGIN      
        1 ccggataacg gcatgatgga atccttcttt ggcattctca aatctgaaat gttttatgga
       61 ctcgagacaa cttatcaatc acttgacaag cttgaagaag ctattacaga ttacattttt
      121 tactacaaca acaaacgaat taaagcaaaa ctaaaaggat ttagtcctgt ccaatacaga
      181 actaaatcct ttcaataatt atttgtccaa ctttttgggg tcagtacact cctagttaac
      241 gactttgatt gattttatta tgatgaatcg tgatttctga aaacaaaatt ttcttcatgg
      301 atttggcgtg gaacttttac aataaaaaca ctaacctctc cctatcgttt tttcaggtga
      361 atgcttggaa ttggtataat aagcggacac gaatcaggtg aaaacaggga aagtatttga
      421 aaaggcgttt aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag
      481 ttagtttatt ttgcaactta gacatcaagg taggttaaac ccttcatgga aaaatcgaga
      541 ctcttagcac tatgggttaa actaccactg gagacgtaat caatcgctaa accacgaaaa
      601 cggctaatag tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt
      661 agagtaatgg cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcaaca
      721 cccgccgccg cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc
      781 acaaaagggg cataggcacg cgcttgagca atcgcctttt gaacactacc tactgccgca
      841 atgtgattgt cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg
      901 ccaactctca cggcatattt ctcaaaaaga cgtaaattag gagtggtttt tcgagtatca
      961 aataccttaa tgcgatcatc gcctaaggct tctacataag cagctgtcat cgaagcaatc
     1021 cctgataaat gttgtaaaaa attcaaggca acgcgttcac atgttaagag gcttctcacc
     1081 gagcctatga tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga
     1141 tgaggattct ggaaggtcac ctcggcatca aatagggtaa aaaccctttg aaaaacggtt
     1201 agccccgcta aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga
     1261 tcaaaaatgg cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc
     1321 aatgtatcat ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc
     1381 tctattttta atatcacttg taagcactag aggcaattgc tattaacttc cgtaggaaat
     1441 cacaaacctg aatacctcat tttaaatccc aacaagtgtc aagacaattg taattttttt
     1501 gtgtataata gtcaagtacc aataggaaac aggtggtctt ttgagcgcca aaattgccaa
     1561 cctattttca tattctaact aaaggacaat tcaatgattc atttaataat aattagcgcc
     1621 attgctctag ccattggaat tggttaccgc accaaaatca atattggcct gctggctatt
     1681 gctttttctt acctcatcgc aaccactctc atgggattaa gccccaaagc acttcttcat
     1741 ttttggccaa cctcactctt ttttaccatt tttagcgtct ctctctttta taacgttgca
     1801 acaactaacg gcactcttga tgttttggct caacacattc tctaccgcac acgcacccac
     1861 cctgacgccc tctacatgat tttatacctg atagcaaccc ttttgtctgc tttaggtgct
     1921 ggatttttca ctactatggc cgtttgctgt cctctagcga ttaccctctg tcaaaaagcg
     1981 gacaaacact ctttgattgg agctcaagcc gtcaattggg gagcttcagg aggggctaat
     2041 ttgataacca gtggctcagg cattgtcttt caaggcctgt ttaagcaaat gggatgggaa
     2101 gagcaagctt tttcacttgg caatcatatc tttatcgtca gcattatcta cccactcatc
     2161 gtcttgcttt tattatcttg ttacatccgc tacagtaagg gaagaacaaa ctcatccttg
     2221 actattgacc aaccaccaat cctcagcaag gtccaaagac aaaccacctt gctcatgatc
     2281 agcagcatgg ttttggtttg gctttttccc ttgttgcatc tcattttccc aaacatcgca
     2341 tggatagcta cttatcgaca aacatttgat attggctttg tctcaatact catggtctgc
     2401 ctcgccttaa ggctcaaatt agggaagcaa gaagccattt tggctaaggt tccctgggct
     2461 ataattatca tgctctgcgg catgagctta ctaatgtctc tagcggtcaa gtcaggttta
     2521 gttacactga tagggcacct cataacaaca accattcctc atttctggtt acctctgttc
     2581 ttttgtgtga tagccggagt gatgtcactc tttagttcca ccctatccgt tgtagcccca
     2641 actctctttc ccatcattgc taccatcagt gctcaaagtc ctcacattga tattcgctta
     2701 ctcacaacag ccactattat tggcgctcta tctactaata tctctccttt ttcatcagct
     2761 ggttccctca ttcaactctc ccttccccat atagaggaac gcagtcttgc tttcaaaaaa
     2821 caaattcttc tgggtgtgcc catcagctta agtttggcac tcttgaccat ctggattctc
     2881 atgctgctag cttccttaag ttagatttat tgtctaactt aaggttggac ttggtataat
     2941 aaagtagaca caaaattaag tggaaacgag gaaaagtcat tatgccaaga aaaacctttg
     3001 ataaagcctt caaactctct gctgtaaaac tcatccttga ggaagagtag cctgtaaaaa
     3061 tggctagttc aactttaaaa attcatccca atagtcttta tcgatggatt caagaatatg
     3121 aaaaatatgg agaaagtgcg ttcccaggac atgggagcgc acttcgtcat gctcaatttg
     3181 agacaaaaaa acttgaaaaa gagcacaaac tgctacagga ggaattagct cttctaaaaa
     3241 agttccaggt ctttttgaag ccaaaccgga aataaaattt cagtttctga aggaaaatag
     3301 tgttagcttg aatagtcatc acgcttgtca aactcttcaa gtctcccgtt caggtttcta
     3361 tgcttattta aaacgtcgtc cctcttcaag gcatgttgag aatgaagctt tgaaggaaat
     3421 gattaaagcc attttctatg aacataaaga gcgttacgga agtgtacgaa ttacccaaga
     3481 actttgtaga cgtggcatcc atgtcaatta taaacgtgtt ggtagactcc ttcatcagct
     3541 aggtctctat gctaaaggaa gtcgatatca atataaatac tataaccgtc gacgttcttc
     3601 attaactcgt cccaatcttg ttaatcaatg tttccaagcg actggtaaga ataaattatg
     3661 gctaggagac ctaacctaca ttcctacaca agaaggaata ctttatgtgt ctgtctttat
     3721 agacgtttat agtagaaaga ttgttggttg ggcaatgggc cgacgtatgc aagacaagtt
     3781 ggtaacagaa gctttcaatc aagcttataa tagagaaaag cctaaagaag gggtaatcgt
     3841 ccatacagat cagggttctc aatataccgg agcatgattt caggacctac ttagacagaa
     3901 aaaatgtaag tccaggatga gtcgaaaagg taatccatac gataatgcac tcatggaatc
     3961 cttttataaa acattaaaaa gagagcttgt caatgatgct catttcgcaa ctattgagca
     4021 agctcagctt gagattttta aatatagtga gacttactat aaccctaaac gtctgcattc
     4081 agctttaggg tatctctcac ctgttgaatt tgaaaaaata gttactcatt agcttaactt
     4141 tatgtctatt ttttcttgac aagtccaggg tatgaagtcc ctttatacac atactttcaa
     4201 aacagctctc aatcctctgt ccgctacaaa aatacgtcac cgctgccctc cagctgcctc
     4261 attcaacgac aaacttgaag ccacaaacag actcatcaag ggcattaagt acaatgcctt
     4321 tagatttcag aactttgaca actttaaaac caaaatcctc atcgctttga acatccaaaa
     4381 agagagaacc aatctgattc tctctcgttg ttaatgataa gtcacccact acagttgaca
     4441 atgagtctct tacttcctgt ttactcattt aatagctctt ctggttccca agattgatta
     4501 aactcatggt ccttaaaaag agaagccaat cctgttattt gtttcagtct taaaatttca
     4561 tctttatcca ttcctaaatg ttttgcaatc cagttatcac ttcgcccaca ctcatgaaga
     4621 tcctttacaa tctgactcat caaatcaaca tcatgacttc ctctagctct attatgtcga
     4681 atggtagaag ccattcgata gtctaatgac ttatcaataa cagaaacagg taatctccca
     4741 ctttcccttt cataaatatc tgaataatct agcattatac gatatctatg aaaaccatca
     4801 acaatactat accgatcctc ttccttatcg taatagcaaa caatcggcat agtataacca
     4861 tcagatttta tactatcata caataatttc atttcaggcg gagcaactga attcggatta
     4921 taatcatttg gagaaatctt ttcaattgga attgatttaa tctcatagac tggactaata
     4981 aaattactca ctttctaact cctttaaact cgtcttatat ttctctttta aaaaggctac
     5041 tattttttgt tgctctcttg tcaaaccaaa ccccatagtt cgacaaatat gatcgttttt
     5101 taaaatacag aaacacattc gtttccagct tggtatatcc tttgttgtta caatatcgtc
     5161 tgtatcatca ggaatttgat ctaaaaaaat aacccttgaa tgtttaaaag aggtataatt
     5221 tgaaatacca tttctagcaa tacgatatcc tttttcaatt agttcattaa ttgtttcctc
     5281 cgcaagtcct ccgcctgttt tatgccaaaa gtctattgat ttattaaatt ttctaacata
     5341 attatttctt aacctcactg gtagcgttga taaaagaaac tgagtgtacg acttccacga
     5401 atgacccttt ggtaaagcaa ttgatttata tcccattgct ttagtacgtc cataaatatt
     5461 cgaaaagtta actccttgaa cacgtcccaa aagctttacc caagtttctt gatctattat
     5521 tctataaaga tttaggctat caacagcata gtcttgaaaa ggagatgcaa ctctcatttg
     5581 tgatggtttt aaacccgctt tatagaatag atcataaagt tcgttataag aataagaaaa
     5641 cttatagtaa gcatgccata tgtcttccac tgaccaatca tataagggag atgctgtcca
     5701 gacatctttg aattgtttgg taatccagca ttccttttga taaccatact ttttattgat
     5761 aaaaccacta tatctgtgta aggattctga agcacggttt cctaatatac aaactgtttt
     5821 ttgatttccg tgaatttgtt tataccacct accaaattgt ttcgctaaat cctcctgatt
     5881 cattttataa cgataagtag taattgaatt attttccaaa ttaataacat aatcttgaga
     5941 tggcattggt cttacccaga tatcttctgt tttgtcatcc cacggatacc aaaacatttc
     6001 ataactacta agtgcagttc tagtagccat cggtaagcac acccaataca aagaaacttt
     6061 ttttctacct tctaaagaag tgaatgtttc ttgaacatat tttgttgtta aactgtactg
     6121 tgcttcaaaa tcttgatgaa acacacctat ttctctatcc ggataatatt tatctctaaa
     6181 atccagtaaa atattaagaa gtaacccact atcttttcca cctgagaagg aaatatagac
     6241 aataggaaat t
//
LOCUS       DAUGJR010000062         6021 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUGJR010000062 DAUGJR010000000
VERSION     DAUGJR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6021
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.062"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            125..4231
                     /gene="cas9"
                     /locus_tag="VH800_001640"
     CDS             125..4231
                     /gene="cas9"
                     /locus_tag="VH800_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEQ8362691.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSK
                     SRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKE
                     HPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLGGD"
     gene            4231..5100
                     /gene="cas1"
                     /locus_tag="VH800_001641"
     CDS             4231..5100
                     /gene="cas1"
                     /locus_tag="VH800_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8362692.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKA
                     LNNEGKGVPEFRI"
     gene            5097..5438
                     /gene="cas2"
                     /locus_tag="VH800_001642"
     CDS             5097..5438
                     /gene="cas2"
                     /locus_tag="VH800_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8362693.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5428..>6021
                     /gene="csn2"
                     /locus_tag="VH800_001643"
     CDS             5428..>6021
                     /gene="csn2"
                     /locus_tag="VH800_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEQ8362694.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYEEDSEL
                     KFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPR"
BASE COUNT         2100 a          883 c         1191 g         1847 t
ORIGIN      
        1 agagatattt tgaaaaagaa aaattaaagc atattaaact aatttcggag gtcattaaaa
       61 ctattattga aatcatcaaa ctcattatgg atttaattta aactttttat tttaggaggc
      121 aaaaatggat aagaaatact caataggctt agatatcggc acaaatagcg tcggatgggc
      181 ggtgatcact gatgattata aggttccgtc taaaaagttc aaggttctgg gaaatacaga
      241 ccgccacagt atcaaaaaaa atcttatagg ggctctttta tttgacagtg gagagacagc
      301 ggaagcgact cgtctcaaac ggacagctcg tagaaggtat acacgtcgga agaatcgtat
      361 ttgttatcta caggagattt tttcaaatga gatggcgaaa gtagatgata gtttctttca
      421 tcgacttgaa gagtcttttt tggtggaaga agacaagaag catgaacgtc atcctatttt
      481 tggaaatata gtagatgaag ttgcttatca tgagaaatat ccaactatct atcatctgcg
      541 aaaaaaattg gtagattcta ctgataaagc ggatttgcgc ttaatctatt tggccttagc
      601 gcatatgatt aagtttcgtg gtcatttttt gattgaggga gatttaaatc ctgataatag
      661 tgatgtggac aaactattta tccagttggt acaaacctac aatcaattat ttgaagaaaa
      721 ccctattaac gcaagtggag tagatgctaa agcgattctt tctgcacgat tgagtaaatc
      781 aagacgatta gaaaatctca ttgctcagct ccccggtgag aagaaaaatg gcttatttgg
      841 gaatctcatt gctttgtcat tgggtttgac ccctaatttt aaatcaaatt ttgatttggc
      901 agaagatgct aaattacagc tttcaaaaga tacttacgat gatgatttag ataatttatt
      961 ggcgcaaatt ggagatcaat atgctgattt gtttttggca gctaagaatt tatcagatgc
     1021 tattttactt tcagatatcc taagagtaaa tactgaaata actaaggctc ccctatcagc
     1081 ttcaatgatt aaacgctacg atgaacatca tcaagacttg actcttttaa aagctttagt
     1141 tcgacaacaa cttccagaaa agtataaaga aatctttttt gatcaatcaa aaaacggata
     1201 tgcaggttat attgatgggg gagctagcca agaagaattt tataaattta tcaaaccaat
     1261 tttagaaaaa atggatggta ctgaggaatt attggtgaaa ctaaatcgtg aagatttgct
     1321 gcgcaagcaa cggacctttg acaacggctc tattccccat caaattcact tgggtgagct
     1381 gcatgctatt ttgagaagac aagaagactt ttatccattt ttaaaagaca atcgtgagaa
     1441 gattgaaaaa atcttgactt ttcgaattcc ttattatgtt ggtccattgg cgcgtggcaa
     1501 tagtcgtttt gcatggatga ctcggaagtc tgaagaaaca attaccccat ggaattttga
     1561 agaagttgtc gataaaggtg cttcagctca atcatttatt gaacgcatga caaactttga
     1621 taaaaatctt ccaaatgaaa aagtactacc aaaacatagt ttgctttatg agtattttac
     1681 ggtttataac gaattgacaa aggtcaaata tgttactgaa ggaatgcgaa aaccagcatt
     1741 tctttcaggt gaacagaaga aagccattgt tgatttactc ttcaaaacaa atcgaaaagt
     1801 aaccgttaag caattaaaag aagattattt caaaaaaata gaatgttttg atagtgttga
     1861 aatttcagga gttgaagata gatttaatgc ttcattaggt acctaccatg atttgctaaa
     1921 aattattaaa gataaagatt ttttggataa tgaagaaaat gaagatatct tagaggatat
     1981 tgttttaaca ttgaccttat ttgaagatag ggagatgatt gaggaaagac ttaaaacata
     2041 tgctcacctc tttgatgata aggtgatgaa acagcttaaa cgtcgccgtt atactggttg
     2101 gggacgtttg tctcgaaaat tgattaatgg tattagggat aagcaatctg gcaaaacaat
     2161 attagatttt ttgaaatcag atggttttgc caatcgcaat tttatgcagc tgatccatga
     2221 tgatagtttg acatttaaag aagacattca aaaagcacaa gtgtctggac aaggcgatag
     2281 tttacatgaa catattgcaa atttagctgg tagccctgct attaaaaaag gtattttaca
     2341 gactgtaaaa gttgttgatg aattggtcaa agtaatgggg cggcataagc cagaaaatat
     2401 cgttattgaa atggcacgtg aaaatcagac aactcaaaag ggccagaaaa attcgcgaga
     2461 gcgtatgaaa cgaatcgaag aaggtatcaa agaattagga agtcagattc ttaaagagca
     2521 tcctgttgaa aatactcaat tgcaaaatga aaagctctat ctctattatc tccaaaatgg
     2581 aagagacatg tatgtggacc aagaattaga tattaatcgt ttaagtgatt atgatgtcga
     2641 tcacattgtt ccacaaagtt tccttaaaga cgattcaata gacaataagg tcttaacgcg
     2701 ttctgataaa aatcgtggta aatcggataa cgttccaagt gaagaagtag tcaaaaagat
     2761 gaaaaactat tggagacaac ttctaaacgc caagttaatc actcaacgta agtttgataa
     2821 tttaacgaaa gctgaacgtg gaggtttgag tgaacttgat aaagctggtt ttatcaaacg
     2881 ccaattggtt gaaactcgcc aaatcactaa gcatgtggca caaattttgg atagtcgcat
     2941 gaatactaaa tacgatgaaa atgataaact tattcgagag gttaaagtga ttaccttaaa
     3001 atctaaatta gtttctgact tccgaaaaga tttccaattc tataaagtac gtgagattaa
     3061 caattaccat catgcccatg atgcgtatct aaatgccgtc gttggaactg ctttgattaa
     3121 gaaatatcca aaacttgaat cggagtttgt ctatggtgat tataaagttt atgatgttcg
     3181 taaaatgatt gctaagtctg agcaagaaat aggcaaagca accgcaaaat atttctttta
     3241 ctctaatatc atgaacttct tcaaaacaga aattacactt gcaaatggag agattcgcaa
     3301 acgccctcta atcgaaacta atggggaaac tggagaaatt gtctgggata aagggcgaga
     3361 ttttgccaca gtgcgcaaag tattgtccat gccccaagtc aatattgtca agaaaacaga
     3421 agtacagaca ggcggattct ccaaggagtc aattttacca aaaagaaatt cggacaagct
     3481 tattgctcgt aaaaaagact gggatccaaa aaaatatggt ggttttgata gtccaacggt
     3541 agcttattca gtcctagtgg ttgctaaggt ggaaaaaggg aaatcgaaga agttaaaatc
     3601 cgttaaagag ttactaggga tcacaattat ggaaagaagt tcctttgaaa aaaatccgat
     3661 tgacttttta gaagctaaag gatataagga agttaaaaaa gacttaatca ttaaactacc
     3721 taaatatagt ctttttgagt tagaaaacgg tcgtaaacgg atgctggcta gtgccggaga
     3781 attacaaaaa ggaaatgagc tggctctgcc aagcaaatat gtgaattttt tatatttagc
     3841 tagtcattat gaaaagttga agggtagtcc agaagataac gaacaaaaac aattgtttgt
     3901 ggagcagcat aagcattatt tagatgagat tattgagcaa atcagtgaat tttctaagcg
     3961 tgttatttta gcagatgcca atttagataa agttcttagt gcatataaca aacatagaga
     4021 caaaccaata cgtgaacaag cagaaaatat tattcattta tttacgttga cgaatcttgg
     4081 agctcccgct gcttttaaat attttgatac aacaattgat cgtaaacgat atacgtctac
     4141 aaaagaagtt ttagatgcca ctcttatcca tcaatccatc actggtcttt atgaaacacg
     4201 cattgatttg agtcagctag gaggtgactg atggctggtt ggcgtactgt tgtggtaaat
     4261 acccactcga aattatccta taagaataat catctgattt ttaaggatgc ctataaaacg
     4321 gagctgatcc atttatcaga aattgatatt ttgttattag aaacgaccga tattgtcttg
     4381 tccactatgc tggtaaaacg gctagtggat gagaatgtcc ttgtcatatt ctgtgatgat
     4441 aaacgattac caacagctat gctgatgcct ttttatggtc gtcatgattc gagtttacag
     4501 cttgggaaac aaatgtcctg gtcagaaaca gtcaaatcgc aggtttggac gacgattatt
     4561 gctcaaaaga ttttgaatca atcttgctat ctaggagcat gctcctattt tgaaaaatcc
     4621 caatctatta tggatttata tcatggtttg gaaaattttg atccgagtaa tcgagaaggg
     4681 catgcagcga gaatttattt taatacactt tttgggaacg atttctcaag agatttggag
     4741 catccaatca atgcaggtct ggattatggt tatactttat tattgagtat gtttgcgcgt
     4801 gaagtggttg tgtctggatg tatgactcag tttgggctta aacacgctaa tcagtttaat
     4861 cagttcaatt ttgctagcga tattatggaa ccatttaggc ctttagtgga taagattgtt
     4921 tatgaaaatc gaaatcagcc ttttcccaaa ataaagagag agttatttac tttgttttca
     4981 gatacatttt catataatgg taaagagatg tatctcacga atattattag cgattatact
     5041 aaaaaagttg tcaaagctct gaataatgaa gggaaaggag ttcctgaatt taggatatga
     5101 gttatagata tatgagaatg atacttatgt ttgatatgcc gacggacacc gctgaggaac
     5161 gaaaagccta tcgaaaattt cggaaatttt tacttagtga agggtttatc atgcatcaat
     5221 tttctattta tagtaagttg ctgttgaata atacagctaa caatgccatg attggtcggc
     5281 tgagggagca taatcctaat aaaggaaata ttacattact aacggtcacg gaaaaacagt
     5341 ttgcacgaat gatttattta catggtgaaa gaaataattg tattgcaaac tccgatgaaa
     5401 gacttgtatt tcttggggag gcttttgatg aatcttaatt tttccttact agatgaaccg
     5461 attccattaa gaggcggtac aattcttgtg ctcgaagatg tctgtgtatt ttcaaaaata
     5521 gtgcaatatt gttaccaata tgaggaagat tctgaactta aattttttga tcacaagatg
     5581 aaaacaatca aagaatcaga aatcatgctt gtaacagata ttttaggatt tgatgttaac
     5641 tcctcaacca ttttaaaatt gattcatgca gatttagaat ctcaatttaa tgagaaaccc
     5701 gaagtgaaat cgatgattga caaattggtt gctacgatta cagaactgat tgtctttgaa
     5761 tgcttagaaa atgaattaga tttagagtat gatgaaatca caatcctgga attgattaag
     5821 tccttaggag taaaagtaga aacgcaaagt gatactattt ttgaaaaatg tctagagata
     5881 cttcaaattt tcaaatatct cactaagaaa aagttgctta tttttgtcaa tagcggagct
     5941 tttctaacaa aggatgaagt ggctagttta caagagtata tatcattgac aaatttaaca
     6001 gttctctttt tagaaccacg t
//
LOCUS       DAUGJR010000063         6013 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUGJR010000063 DAUGJR010000000
VERSION     DAUGJR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6013
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.063"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            202..813
                     /gene="rpsD"
                     /locus_tag="VH800_001644"
     CDS             202..813
                     /gene="rpsD"
                     /locus_tag="VH800_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEQ8362695.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(967..1500)
                     /locus_tag="VH800_001645"
     CDS             complement(967..1500)
                     /locus_tag="VH800_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8362696.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            1635..3908
                     /locus_tag="VH800_001646"
     CDS             1635..3908
                     /locus_tag="VH800_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEQ8362697.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNTEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPLNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEELSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADG
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(4026..5105)
                     /locus_tag="VH800_001647"
     CDS             complement(4026..5105)
                     /locus_tag="VH800_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEQ8362698.1"
                     /translation="MKNISRKCFMTSVVCIILGGILLGTGYATGGLQDIKHQTAPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKLIDPIVTTVTGKTLSLSQTP
                     KDVVITGGIEILGFTLNNSRQEKNYRSITITVPEKTSLNEVKASNVPHTTLSNLTVQD
                     MQFDGNLTLLHTKVKKATITGMLEATKSQLTNLELKADYSFSNLTDSSVENGTISLGN
                     GQLTTKDTTLKAVNIQSLHPGGIEAERTTLENVTFTVSKSKEEEENDYYDNDAIFTAH
                     ALTLKGTNTITGGDIDVDITLTKAKAIAYRARTENGKVSLGSQLTPAKIGKESTSDVI
                     SYVAENKAATGNLTVNLNKGDITIK"
     gene            complement(5102..5689)
                     /locus_tag="VH800_001648"
     CDS             complement(5102..5689)
                     /locus_tag="VH800_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEQ8362699.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATAFLRFSGRAFVAFIKWISNKKGAQA"
     gene            complement(5676..6002)
                     /locus_tag="VH800_001649"
     CDS             complement(5676..6002)
                     /locus_tag="VH800_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEQ8362700.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
BASE COUNT         1799 a         1132 c         1182 g         1900 t
ORIGIN      
        1 atgatagata gactgacttt acaaaacaac tttcttatgg taaactgttc tttgtgcgaa
       61 ataacagcag aaaaatatga agctcgtcaa caggtggtta tctattcaag taacctttgc
      121 tgtttaggcg aaaaccccct gcacgaatca ggatttttta aaccgttatt tcctcaaaaa
      181 atttagagga ggacatgtaa tatgtcacgt tatactggtc catcatggaa acaatcacgt
      241 cgccttggtt tatcacttac aggcacaggt aaagaattgg cacgtcgtaa ctacgttcct
      301 ggtcaacacg gtccaaacaa ccgtagcaaa ctctcagaat atggtttgca gttagctgag
      361 aaacaaaaac ttcgtttctc atacggttta ggtgaaaaac aattccgtaa cttgttcgtt
      421 caagctacaa aaatcaaaga aggaactctt ggtttcaact ttatggttct tttagaacgt
      481 cgtcttgaca acgttgttta ccgtctaggt ttagcaacta ctcgtcgtca agcacgtcaa
      541 ttcgttaacc acggtcacat ccttgttgac ggtaaacgcg ttgatatccc ttcataccgc
      601 gttgatccag gtcaagtgat ttcagttcgc gaaaaatcaa tgaaagtacc tgcaatcctt
      661 gaagctgttg aagctactct tggacgtcca gctttcgtat catttgatgc tgaaaaactt
      721 gaaggttcat tgactcgcct tccagaacgc gatgaaatta acccagaaat caatgaagca
      781 cttgtcgttg aattctataa caaaatgctt taattttaag attaaactta caaaaagcct
      841 atttaatagg ctttttttgt atctcataac aaatttatcc tgatcccttc attttactat
      901 ggcttctaaa aaagttatca ctaaggctga tgacttgtaa aatgatactt tcgtaagggt
      961 tattatttag gtactcgtaa gcattttgag aacgaattgt gtcatttctt gaggtgattc
     1021 ttttttacct ttagcaatcc aactttgaca gacaccaaaa aaagcatggg ctaagtagat
     1081 actttggtat tctttttccg tttgagataa ctcttcggta ctgaacttgt cctgtaaatc
     1141 agtagtgatg agtaggcgaa ctttattgat gataaaggcc tgtatttctt tagtaccgtt
     1201 agcagacaaa agggaagaga gaagctgttc tctttggaga aattcaaata cttcaaggaa
     1261 ggcttgttct ttattttgat attttttctc aaaaatatat tctaatttgt gaaaaaaggt
     1321 ttgctgataa tagtcaatca tttcatattt atctttatag tgtgtgtaaa aactagagcg
     1381 actaattcca gctcttttag ataatttaac tgtggtaata tcgtcaaaac tttcggtttt
     1441 tagtaacata accattgctt ttaaaattgc ttgcttcgta ttttctttac ggttgaccat
     1501 ctaccatctc tccttttgaa cacttttaga cataatgtcc aaaagtgaat ttttttctct
     1561 tgtaaattta aatttaaatt gtataatata ttttatcata atttttgaac agtatgtcca
     1621 ttttaggaga aaatatgtta gaagaattga aaacacttat taaaaatcca aaattaatga
     1681 ttacaatgat tggtgtggcc ctagtgcctg ccttatataa tttatccttt ctaggctcaa
     1741 tgtgggatcc ttatggtcgg gtcaatgacc ttcccattgc tgttgttaat catgataagc
     1801 ctgcaaagag agctgataag tcattgacaa ttgggaatga tatggtggac aagatgtcta
     1861 aaagtaaaga tttagagtat cattttgtct cagctaagca agctcaagag ggacttaaag
     1921 aaggtgatta ttatatggtt attactttac ccgaagatct ttctcaacgg gcagcaacct
     1981 tattaaatac cgaaccccaa aaattaacta tccgttacca aacgagtaaa ggacatggaa
     2041 tggtcgctgc taagatgggg gaaacagcga tggctaagct gaaagagtct gtttcgcaaa
     2101 acattacgaa gacttatacc tcagcagttt ttagcagtat gacagacctc caatcaggat
     2161 taaaagaagc ctcagctgga agtcaagcac ttgcttcagg agcgaagact gctcaggcgg
     2221 ggagtcaaac actttcgacg aacttagcag ccttaacggg tgctagccaa cagtttcaac
     2281 aaggtactgg tcgattgaca tcaggtttga ctacctatac agatggtgtc aaccaagtca
     2341 agaatgggtt aggaacatta tcaacggaca tccccaatta tctgaatggg gtttctaggt
     2401 tatcccaggg agcttctcag cttaatcagg gtctttcaca gttgacacaa gcaacaacac
     2461 tttctgacga gaaagctaag ggaattcaat ccttaattgt aggactacca gtcctaaatc
     2521 aaggcattca gcaactaaat acagagctat caacattgca accccttaac cttaatgctg
     2581 atgagttagg taatagctta ggagctatcg ctcaagctgc caaacaagtc attgctgaag
     2641 agactgccgc tcagaatgaa gaattatcgg ctctccaagc tactagcgtt taccaatcat
     2701 taactgctga acaacaagga gagttagctg cggccctcag tcaatctgat aaaagtcaga
     2761 ccgtatctgc agcccaaact attttaagtt ctgttcaaac tttgtcaaca agtttacagt
     2821 ctctctctca agaagatcag tcaaaacagt tggagcaact taaggaagct gttgcacaga
     2881 ttgctaatca atccaatcaa gctttgccgg gagcaagttc tgctttaact gaattatcaa
     2941 cgggattagc aaaggtaaat ggtagcttaa atcaacaagt tctaccagga agtaatcaat
     3001 tgacaacagg attagcacaa ttaaacaggt ataatactgc cattggttct ggggtaataa
     3061 aactctcaga aggtgccaat gccttgtcat ccaagtccgg agaattacta gatggtagcc
     3121 atcaattatc agaaggtgct actaaactag ctgatggtag ttctcaattg agtcagggtg
     3181 gtcatcaatt aacgagcgga ttgactgaat tatcaacagg attgtcaacc ttaaatggtt
     3241 ccttagccaa agcctctcag cagttatcgc ttgtttctgt gactgataaa aatgctaaag
     3301 ctgtcgcaaa acctcttgtg ttaaatgaga aagacaaaga tggtgttaag acgaatggga
     3361 tcgggatggc accttatatg attgctgttt ctctaatggt tgtggccctt tcaaccaacg
     3421 tcatttttgc taattcttta tctggtcgtc cggtcaaaga taaatgggat tgggctaaac
     3481 aaaaatttgt tattaatggt tttatttcga ctatgggatc cattgttctc tacttagcta
     3541 ttcaattatt agggtttgaa gcccgttatg gtatggaaac cttaggattt attatgctaa
     3601 gtggttggac gtttatggct cttgtcacag ctttggtcgg ttgggatgat cgatatggct
     3661 cttttgcttc tttggtcatg ttattgcttc aggttggctc ttcaggtggc tcttacccca
     3721 ttgagttaag tggagcattc ttccaaaagt tacatccttt cttaccaatg acttatgtgg
     3781 tatctggttt acgacaaacc atttcattat caggtcatat tggagtagaa gtgaaagtct
     3841 taactggttt cttactggca tttatggtat tagcactact catttatcgt cccaagaaaa
     3901 cagtctaaat aaaataacct caaaaaaaaa acagcatcta aggcagttac actagatgct
     3961 gttttttgtc ttattttgac aataacttga caatttctgt caagtttttt attgtcttgt
     4021 taagattatt tgatagtaat gtctccctta ttgagattaa ccgttaaatt tccagtagct
     4081 gctttattct cagccacata agaaataaca tctgaagttg attccttacc aatcttagct
     4141 ggtgtcagct gtgagccaag ggagacttta ccattttcgg tccttgctct gtaggcgatg
     4201 gcctttgctt ttgtcaaggt tatgtcaaca tcaatatcac caccagtaat agtattagtc
     4261 cctttaaggg taagggcatg agcggtgaag atagcatcat tgtcatagta gtcgttctcc
     4321 tcttcttctt tgcttttaga aacagtgaag gtcacatttt caagggttgt tctctcggct
     4381 tctataccac cagggtgtaa tgattgaata ttgacagctt ttagagtggt atctttagta
     4441 gttagttgtc catttcctaa gctgatggtc ccattttcca cactagaatc agtcaggttt
     4501 gaaaaagaat agtcagcttt taactcgaga tttgttaact gacttttagt ggcttccaac
     4561 ataccagtga tagtagcttt cttgactttg gtatgtaaaa gagtaagatt gccatcgaat
     4621 tgcatatctt ggacagttag atttgacaaa gtggtatgtg ggacattact tgccttaact
     4681 tcattgaggc tagttttttc aggaacagta atggtaatag aacggtagtt cttctcttga
     4741 cgactattat tgagagtaaa acctaaaatt tcaattccac cagtgatgac aacgtcttta
     4801 ggtgtttgcg aaagagatag ggtcttacct gttactgttg tgacgatagg atcaataagt
     4861 ttaggatgtg tgtaataggt cactgttggt ctttgaacgg gtcctgtctc tactgtaata
     4921 gttgaggcag aactgtcaat atcaagagca gttatttggt caaatgtttt gatgaccttt
     4981 ttgggagctg tttggtgttt aatgtcctga agtcctccag ttgcatagcc agtccctaga
     5041 agaatgcctc ctagaataat acataccaca ctggtcataa agcatttgcg tgagatattt
     5101 ttcatgcttg agctcctttc ttattactga tccacttaat aaaggcaaca aaagcccgtc
     5161 ctgaaaaacg aaggaatgct gtggcaataa tccaaataag aagaccacca ccaaaacaca
     5221 acaaggcgct gccgatgccc atagcttgtg caggaataga tgagccaatc aaggtcaagc
     5281 tttcaaacag ggtcactcct gcgacaagaa tacctgcaag cccaaaaatg taggcggcaa
     5341 agatagctgt gagcccgagc attaggcagg caataataaa gagaatcaac gccagcaata
     5401 cgggtaaagc aatcggagca gcaaagaggg acaaaatggt taatccaata attgttgccc
     5461 gatttttggg agttttctcg ggagttgcca agtgttttcc tagaacattt gaaatgattt
     5521 cactggcagc ttccttagga tttcctaaat cgtcgataac ctggctttct ttgtcaggac
     5581 cagcttcatc aaaatattca atataatatt ccatcgcttc atggtagtct tctctaggta
     5641 gtttgcgcaa gtatttatct agttctgcta gatactcagt ccttgtcatg tcttaagctc
     5701 ccttcaataa tcccgtctaa ggcaaattta tagctctgcc attctttttt tagaaaaatc
     5761 agctgtgctc tccccgaaga agtgacagca taatatttac gctttcgtcc ctgatgttct
     5821 tgactataag ttgtcaaaaa acctgctttc tccaattttt taagaatagg atagagagtg
     5881 gattctttga tattagccac tagtttaatg gtttgactaa tatcgtaacc gtaagaatca
     5941 tttttttcga caatggctaa aatcagaaat tcaatcaagg tagccgatac tggaaaatac
     6001 attttaggct cct
//
LOCUS       DAUGJR010000064         5592 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUGJR010000064 DAUGJR010000000
VERSION     DAUGJR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5592
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.064"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1252
                     /locus_tag="VH800_001650"
     CDS             <1..1252
                     /locus_tag="VH800_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8362701.1"
                     /translation="EDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDD
                     ESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQTSFFFSTASKFQE
                     NLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGILQNLFPKTSLAND
                     IAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDR
                     KRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLI
                     GWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAMSNYIRQKLATIKI
                     SKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKIIERLTL
                     KDVVTIGKAFFEKADASDFTVFPK"
     gene            1302..2327
                     /locus_tag="VH800_001651"
     CDS             1302..2327
                     /locus_tag="VH800_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8362702.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIVILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2341..2883
                     /gene="pgsA"
                     /locus_tag="VH800_001652"
     CDS             2341..2883
                     /gene="pgsA"
                     /locus_tag="VH800_001652"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEQ8362703.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2885..3724
                     /locus_tag="VH800_001653"
     CDS             2885..3724
                     /locus_tag="VH800_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8362704.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3700..4542
                     /locus_tag="VH800_001654"
     CDS             3700..4542
                     /locus_tag="VH800_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8362705.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREV
                     LKHG"
     gene            4535..5335
                     /locus_tag="VH800_001655"
     CDS             4535..5335
                     /locus_tag="VH800_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8362706.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         1819 a          888 c         1040 g         1845 t
ORIGIN      
        1 cgaagacctt tactatgtaa aattagaaaa tggtttaact gtttatttta taaaaaaaat
       61 agggttttta gaaaaaacag ctatgttgac agtaggtttc ggttctcttg acaataagtt
      121 gacagtcgat gacgaatcac gagatgctcc agcaggtatt gcacactttt tagaacataa
      181 actctttgaa gatgaatcag gtggagatat ttcattaaag tttacacagc taggagcaga
      241 gacaaatgcc tttacaactt tcaaccaaac gagtttcttc ttttcaacag ctagtaaatt
      301 tcaggaaaat ttggaactcc ttcaatattt tgttctttct gctaatataa cagatgaatc
      361 tgttagtaga gaaaaaaaaa taatcgggca agaaattgat atgtatcaag atgatgctga
      421 ctaccgtgca tatagtggaa tccttcagaa cttatttcca aaaacaagtt tagctaatga
      481 tattgctggc tcaaaagcat ccattcaaaa gatcacgaaa atattattgg aaacgcatca
      541 tacttatttt taccaaccta ctaatatgag tctattcatt gtcggtgata ttgatattga
      601 cgaaactttt ttagctattc aaaggtttca aaccacatta tcctatccag atagaaaaag
      661 ggtaactgtt gatcctttac actactatcc tgtcattaaa tcatcttctg ttgacatgga
      721 tgttactact gccaagctgg ttgttggttt tcgagggtat ctgaccttaa ctcagcattc
      781 actattaacg tatcgtattg ccttgaagct atttttatca atgcttatag gttggacttc
      841 taaaatctat catacgctat atgaagatgg taaaatagac gattcatttg atgtggatgt
      901 tgaaattcat cataattttc aatttgtatt aatatcactt gatacaccag agcctatcgc
      961 aatgtctaac tatatccgtc aaaaattagc tactataaag atatcaaaag agtttacaaa
     1021 tgagcactta aatctattaa aaaaagaaat gtatggtgac tttattcaga gtttagactc
     1081 tatagaacat ttaacccatc agttcagtct atacctgtct gattctgata aagaaacata
     1141 ttttgatatt ccaaaaatta tagaaagact cactctaaaa gatgttgtta caattggaaa
     1201 agcatttttt gaaaaagctg atgcttcaga cttcacagtc ttcccaaaat agatgaaaat
     1261 ctgttataat agggttacta tattattttt gaggtacctg tatgagtgaa aaaagtcttg
     1321 gtgaagtgtt aagagaatcg cgtgttggaa aaaatatcac actagatgat atagaattga
     1381 agacagggat ttcttcccat tacttgctgg caatggaatt ggatcagttt aaaattattc
     1441 cggaagaaaa atttgatcaa tttttaaaag aatatgctga cattgttgag ttagatttca
     1501 atactttaaa aagacgatac cgttatcaag ttaattccaa aaaagacagt gatataaaat
     1561 ctgtaactga gattgttgaa gagaagttaa gtaagaaacg attacaagag aagttgttat
     1621 cacatcagag catggggtat ggtcaaccgt tagaagtttc taaaaacaaa gaaaccttag
     1681 ttatccctgt aaagactgtt ggtttagata gcaaatcgcc actaaaaacg atatcgcctg
     1741 ttagccaatt taaatcagat aacaggttaa ttcctaaaaa aaatgtgtca cgtatgaggc
     1801 gaaatagcac tgacagtcgt tctaaaacgt cactatttcc catagttata ttaggaacga
     1861 ttgcttttgc aattatcagt gttatcattt taggtgtttg gcaacaattc gaaaagagtc
     1921 aaagagctaa agaagctgaa gttgctttgc ttaaagcctc tgagcagtct actaacggtt
     1981 taaaaaataa ttcaaatgat cgcaaaactc aagtcacaac tgaggggtcg ggtaattatt
     2041 taatagcgac tgttactaaa tctaaagaga ccgttgatat cagtgtgtct ttaaccgagg
     2101 cacaaagtag ttggatttct ctaacaaatt cagaaattgg tgaaggtggt ataacattga
     2161 ctcaagactc gccaacttat acagcgactt tacctgcaga aataacagaa tcattgttga
     2221 cacttggtgt gacaaaaggt gtatctgtaa caattgatgg acaacctgtt gatctatcac
     2281 ctttaacaag tactgactta agttatatca cgtttaagat ccaataatta aggtagacta
     2341 atgataaaaa aagaaaatat tcctaatcta ttaactcttg ttcgaatcgc aatgattcct
     2401 ttctttcttt ttattacttc ctcatctaat aaggtggggt ggcatatttt tgcagctgtg
     2461 atttttgcaa ttgccagttt taccgattat ctagatgggt atcttgcgcg taagtggcat
     2521 gtagccagta attttggaaa gtttgccgat cctctagcag ataagatgct tgtcatgagt
     2581 gcctttatca tgttagttgg acttggctta gttcctgcgt gggtgtcagc tgttattatt
     2641 tgccgagaat tggcagtaac tggtcttcga ttactacttg ttgaaaccgg aggaaaggtc
     2701 cttgcagctg ctatgccggg aaaaatcaaa acagcgacac aaatgttgtc tattatttta
     2761 ttactttgcc attggatatt cctaggaaac gtcttactct atattgctct ttttttcact
     2821 atttattctg gatatgatta ttttaaagga gcaagctttc tttttaagga tacgtttaaa
     2881 taacatgtca gctattattg aacttaaaaa agttacattt aattaccata aagaccaaga
     2941 aaaaccaaca ttagatggcg tatcgtttca tgtgaaacaa ggtgagtggc tgtctatcat
     3001 tggccataat ggatctggta aatcaacgac tattcggtta attgatggat tattggaacc
     3061 agaatcaggg tctattattg ttgatggaga tctactaacc ataactaatg tttgggaaat
     3121 tcgtcataaa attggtatgg tctttcaaaa ccctgataat cagtttgttg gagcaactgt
     3181 tgaagatgat gttgcttttg ggcttgaaaa taaaggtatt gcacatgaag atataaaaga
     3241 gagggttaat catgctttag agttagtcgg catgcagaac tttaaagaaa aagaaccagc
     3301 ccgtttatct ggtggccaaa aacagcgcgt agctattgca ggtgcagttg ctatgaagcc
     3361 taaaattatt attttagatg aagctactag tatgcttgac cctaaaggac gattagagtt
     3421 aatcaaaact ataaaaaaca tccgtgacga ctaccagctg actgttattt ccattactca
     3481 tgacttagat gaagttgctc ttagtgatag agttttagtg atgaaagatg gtcaagtgga
     3541 atcaacatca acaccagaac aattatttgc aagaggggat gaactactcc aattaggtct
     3601 tgatatccct tttacaacat ctgttgtaca gatgcttcaa gaagaaggtt atcctgttga
     3661 ctatggatat ctcacagaaa aggaattaga aaatcagtta tgtcaattaa tctccaaaat
     3721 gtaagttata cttatcaagc agggactcct tttgaagggc gtgccctttt taacattaat
     3781 ttagatattt tagatggttc ttatacggct tttatcggac atactggatc cgggaaatcg
     3841 accattatgc aattgctaaa tggtttacac gttccgacaa cgggaattgt cagcgtagat
     3901 aaacaagata taacgaatca ctctaaaaat aaagagatta aatctattcg aaaacatgta
     3961 ggattagttt ttcaatttcc agaaagtcaa ctatttgaag agacagtttt gaaagatgtt
     4021 gcttttggcc ctcaaaattt tggggtctct ccggaggaag cagaagcttt agcgcgtgaa
     4081 aaactagctc ttgttgggat ttcagaaaat ctttttgaaa agaatccatt tgaactctca
     4141 gggggtcaaa tgcgtcgtgt tgctattgcg ggtatccttg ctatgcagcc aaaggtttta
     4201 gttttagatg aaccgactgc tggtcttgat cctaaagggc gtaaagaatt aatgactatt
     4261 tttaaaaagt tacaccaatc tggcatgact attgttttag taacccatct gatggatgat
     4321 gtggccaatt acgcagattt tgtatatgtt cttgacaaag gtaaaattat tttatcagga
     4381 aaacccaaaa caatttttca acaagtcagt ttgcttgaga aaaaacagtt aggagttcct
     4441 aaggtgacta aacttgctca aaggcttgtt gatagaggaa tacctatctc ttctttgcct
     4501 attaccttag aggagctaag agaggtacta aaacatggat aagctgattc ttggtcgtta
     4561 tattcccgga gattctctca ttcatcgtct tgacccaaga agtaaattat tagcgatgat
     4621 tatttatatt gtcattatct tttgggctaa caatgttgtg acaaatttgt tgatgttgac
     4681 ttttacttta gcagttgttt ttttgtcaaa aatcaagttg tctttctttt taaatggggt
     4741 taaaccaatg attggtatta tcctcttcac gactttattt cagatgtttt tctcacaagg
     4801 aggaaaagta atttttagtt ggtggttcat tagcataact gatttaggat tgagccaagc
     4861 tattttaatt tttatgcgtt tcgttctaat tattttcttt tcaacgctgt taacgttgac
     4921 gacaacacct ttaagcctat ctgatgcagt tgaatcatta ttaaaacctt taacaagatt
     4981 taaagttcca gctcacgaga tcggactaat gctttcttta agtttacgtt ttgtgcctac
     5041 tttaatggat gataccacgc gtattatgaa tgcacaaagg gcccgtggag ttgattttgg
     5101 agagggaaat ttaattcaaa aagttaaatc cattattcct attttaatcc ctcttttcgc
     5161 ttcaagcttt aaaagagccg acgcattagc tattgctatg gaagctagag gttatcaggg
     5221 aggagaaggg cgaactaaat atcgtcaatt agactggcag ctaaaagata gtttagctat
     5281 tggaatagtt tctttattgg gtttgctact ttttttcttg aaaacctctt tgtaatattt
     5341 tttagcacaa aacttttctt tattagtaag aagtgaattg tacctcaaaa gttagataca
     5401 atatctaatg attgaggtac ttttcttcat ttgaggaatt gaaaaccgct atctcaacta
     5461 tattaatcct cccaataata acaaatcgaa cgaaatctaa aaggactgag tcctgttcaa
     5521 tacagaacta aattcttagt ttaatgatat tatcccgctt tttaatgttg ctaagaagaa
     5581 gagttttatg at
//
LOCUS       DAUGJR010000065         5398 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUGJR010000065 DAUGJR010000000
VERSION     DAUGJR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5398
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.065"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..517)
                     /locus_tag="VH800_001656"
     CDS             complement(<1..517)
                     /locus_tag="VH800_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEQ8362707.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKG"
     gene            complement(624..1319)
                     /locus_tag="VH800_001657"
     CDS             complement(624..1319)
                     /locus_tag="VH800_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEQ8362708.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            1558..2493
                     /locus_tag="VH800_001658"
     CDS             1558..2493
                     /locus_tag="VH800_001658"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEQ8362709.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIKDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            complement(2793..4655)
                     /gene="cadA"
                     /locus_tag="VH800_001659"
     CDS             complement(2793..4655)
                     /gene="cadA"
                     /locus_tag="VH800_001659"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEQ8362710.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTYILEKVQDLSAFEETIQVEEKQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRTM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(5186..5368)
                     /locus_tag="VH800_001660"
     CDS             complement(5186..5368)
                     /locus_tag="VH800_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8362711.1"
                     /translation="MLTYDEFKQAIDNGYIAGDTVAIVRKDGQIFDYVLPHEKVKNGE
                     VVTKEKVEEVLVELSR"
BASE COUNT         1665 a         1111 c          917 g         1705 t
ORIGIN      
        1 ttcctttgta taagatacct gctaattcta aatcatgctt aatagctaaa aaggcttctt
       61 gactaggaca cgaaattaag tgactatgta gtccttctgt caacgaagac aataactctg
      121 ctttagattg actgagtttg gacatgaaat tagttacatc agagtgtgtc ttaatattta
      181 aaggggctgt tatcataccg taaataggat gttctacctc taccgtcgta ataatccctt
      241 gatgagctaa aataatttct aattcttttt tagtttcttc tacattatgt tggcacacaa
      301 tacgtgcaca aaattggtga ctataaagtg ctgttgacat aatataacct tttggagtcg
      361 aaataatatc aatctgctga gctcgaagaa gagctatatc tccaacgatt acttggcgac
      421 tcactcctaa taacttacct aaacgagtag cagatacagc tttttgttca ctatttaagc
      481 actcaataat tttttgacga cgatcttctg ctttcataat ctatctatcc ttttttattt
      541 ctatcatatc atatttttaa gcagggtttt ctttcttctt aggatataga accaaaaaac
      601 cagaccaaag tctggttttt aagttattca ccaccaaggt agtattcttt aacaatgtta
      661 agtttttcat ctaattcaaa aacaagtggt gggaagtttg gaatttccac atccatgatt
      721 tcgtcatctg aaagaccttt aatgtgtttc acaagagcgc ggattgagtt accatgtgcg
      781 ccaacaaaga cgtttttacc gtcaagaaga gctggagcaa ttttttcttc ccagtaaggc
      841 attgcgcgtt caagagttac ttttaagttt tcagcatctg gaataagggc tgggtcaaga
      901 tcagcataac gacggtcttt gtgtgctgaa tactcatcat ctttagccat agctggcggc
      961 aacacgtcgt atgaacgacg ccagatatga acttgttcat caccaaattg ttctgcagct
     1021 tcagctttgt ttttgccagt caaagcacca tagtgacgct cgttcaagcg ccatgatttt
     1081 tcagttggaa cccacaattg acctgcattt tcaagggcaa ggttagttgt tttgatagca
     1141 cgtgtcaata ctgaagtgaa agcaaggtca aattcaatac ctgcttcttt gatcaattta
     1201 cctgcatcaa tcgcttgttg tgtccctttt tctgaaagat caacatctgc ccaaccagtg
     1261 aagaggttag ctttgttcca ttctgactca ccgtggcgag cgaaaaccaa ttttaccatg
     1321 agttaatatc tccttttaat ttaaaggttg ctaccttttt acagttccta ttttacaaaa
     1381 aatatagcaa aaaagctagt ctattctgac tttattgaaa atcataatgt gactatcatg
     1441 aaaatttcaa atgttcgtca ataacagtaa tatatttaca tttttgtaaa aatagcttgc
     1501 tattattcat gcctagtggt agaatagaaa aaatttgtct aaaatatgga ggaaataatg
     1561 gtttctactg ctacacaaat tggtcatttc tcttttgata actgtttgat gaatgctgct
     1621 ggtgtttact gcatgacaaa agaagagctt atggaggttg aaaagtctca agccgcttcc
     1681 tttgtcacca aaacagggac gcttgaagtt cgtccaggta atccagaacc tcgctacgca
     1741 gatactcgtc ttggttctat caattcaatg ggactcccta ataatggttt tcgctactac
     1801 ttagactttg tcagtgatct tgccaaaacc gggcaacata aacctcactt tctctccgtt
     1861 gtcgggctat ctcctactga aaccgaaacc attttaaaag ccatcatggc ttcagattat
     1921 gagggtctag tggaactaaa cctttcttgc cctaacgttc caggaaaacc acagattgct
     1981 tatgattttg aaaccactga tcaacttcta gagaacatct ttacctatta cactaaacct
     2041 cttggtatca aattacctcc ttattttgac attgtgcatt ttgatcaagc ggctgcgatt
     2101 ttcaataaat accccctttc ctttgttaac tgtgtcaatt ctatcggaaa tgggctggtc
     2161 attaaggatg aacaagtcct catcaagcct aaaaatggct ttggtggtat aggtggagat
     2221 tacatcaaac ctactgctct agccaatgtc catgcgtttt acaaacgctt aaaaccttct
     2281 atccacatta ttggtacagg gggagttaaa acaggacgcg atgcctttga acatattctt
     2341 tgtggcgcca gcatggtcca aattgggaca gcccttcatc aagaagggcc agctatcttt
     2401 gaacgggtca ctaaggaact taaaacgatt atggtagaaa aaggctacca aagcttagac
     2461 gattttcgtg ggaacttacg ttacaaagat taaccttaat agtcaaaaaa gcttggaaat
     2521 gtgcactttg tacactttcc aagcttttta aaatgggaat ttttttgaag ggacagcgtc
     2581 actttcttgg gactgtcttt gctggttgtt tgattcaact tttctttttt gcttgcgctc
     2641 aaattgctga taaaaataga aaaatagaat gattttaatt attgaaaata cagctaaacc
     2701 aatgatcata atagtaaaca tacggcggtt ttctctttca taagtcttac tattattata
     2761 aacactttca agttttcaag caagtttcta aattatttaa aagaaagtaa acgcaagcca
     2821 tttaaaatca ctaaaatcgt tgagccttcg tgtccaacaa caccaagcgg caagttaact
     2881 acctgaaaaa cattggctaa aatcaataag gtaatcacag ataaggcaaa aacaatattt
     2941 tgtttgataa tggtcttcat tgtgcgggaa agttgaatcg aaaatggaat acgagtcaag
     3001 tcatccataa tcacactgtc tgcactttcc attgcaatat ctgttcctga tccaatagca
     3061 taagaaacat ctgcttgagc aagggcagga gcatcattaa taccatctcc taccatagcc
     3121 acaaaaccat atttagtctt taattctgct aacttagcca ccttatcttg aggcatacag
     3181 ttggctacca cttcatcaat accaagtttt tgtgccacat aattggcggt tcgttcttgg
     3241 tcacctgtta acatgactgt tttgattccc atggcatgaa gagacttaat agcacgtttt
     3301 gattctattt tgatatcatc caagagggca tagtaagcta tcaattgatg gtcacgtgaa
     3361 acaaagatta gggttttccc ttgtttttct tccacttgaa tagtttcttc aaaagctgat
     3421 aggtcttgaa ccttttccaa aatgtaggtt ttcttgccaa ttcgccattc ttgcccttga
     3481 tagaagccct gaaaaccttt cccagaaatt tcttctaagt ggtcaaaggt cagtggctcc
     3541 aatttttcag tgtattcaag aagggcttta gaaataggat gggtactagc agtctctgct
     3601 ccttttacca gtctattcac gagcaactca tcttccaaat aatgagcatt cacaacagaa
     3661 ggttttcctt gggtgagcgt tcccgtttta tccatgacaa cagccttaat atctcccatg
     3721 ttatcgacaa tatcccctcc tttgataatc aatccctttc tggctgcacg agaaatagca
     3781 gccaagctag caggtgtgga actggcaatt agggcacatg gtgaagctac tgttaagaga
     3841 atcatccctc ggtaaaaagc agccaaccaa gtccaagaaa gcacaaagtg gctaaagagg
     3901 ataaaggcag gaataaggac gagcacaaat ttgacataac catcttctaa gctttcgata
     3961 aaggtggcgg ttttgctttt cttttcttgg gcagattcca ccagattaat aatcttggca
     4021 aagagagtat cgtcattttc aatagtaacc aacatatcta tggtttgtcc ttggttaatg
     4081 gttcccccaa tcagatcctg gccttctgcc ttatcaacag tgataggctc accagtgacc
     4141 atagattcat caaattgacc aaaaggacta agcaactgcc cgtcaattgg aacagcttcg
     4201 cctttacgaa cttgtaaacg gtcaccaaca ctcaaggatc tggtctcaac ttctaaaata
     4261 tggccatctt cttggtattg acgagctgta tctggcgtca aggacatcaa ggctgaaata
     4321 gcatccttac ttttttccat ggccatttct tcaagcgtat tggacaacga aaagataaaa
     4381 ataagcagag caccctccag ccaatagccg ataattccag caccgatagc tgccaaaatc
     4441 atcaaaatat ccactgacaa gtgtttgttc ttcaccaaat ccaatatacc cgtttttgca
     4501 gacgcatatc ctccaatcaa gaaggctgta atgaaaatag cggaagccac ttgtggaaat
     4561 gagtgtaaaa aggctaggcc aattattatt aataccaaac acgctaaagt ctccatcaaa
     4621 tgaagatggt ctgccatcca ttgtctgatt gtcattttta gttccctcgc aattaaaagt
     4681 tattcaatct ttaagatata ttaattataa taattctaaa taaataagtc aagtaattta
     4741 gaaacattct aaataaactt ttttaaactt accttttgct ttcaaaaatc ctaacttcaa
     4801 ctatttgcaa atatgaaaaa aactccccct acctgcggaa atgatatact aatagaagga
     4861 tgactgacca ttatagagtg catgctttag aacttggctt aactgaagag aaaactacta
     4921 actttatgcc ccaaatataa aaaaagaacc ttgtcgctat caataaacat cgatagcaac
     4981 aagatttttc tagacgaatt atttaacagc gtcttttaaa gattacttaa tattgtgcac
     5041 atataatata ataaactttg attttataaa gctacaaaat aacgaaactt tatataattg
     5101 cttcgaatca actatgtaag ttttaaactt atgcccccta tttacccctt taataaaact
     5161 acttctcagg gggcaaagaa aatacttatc tcgaaagctc caccagcacc tcttccactt
     5221 tttccttagt cacaacttct ccattcttta ctttctcatg tggcaacaca taatcaaaaa
     5281 tctgtccgtc tttacgcacg atcgctactg tatcgcctgc gatatatcca ttgtcaatcg
     5341 cttgcttaaa ctcgtcgtat gttagcattt ttaccctcct acttatttat tcgtattt
//
LOCUS       DAUGJR010000066         5154 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUGJR010000066 DAUGJR010000000
VERSION     DAUGJR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.066"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            101..1649
                     /locus_tag="VH800_001661"
     rRNA            101..1649
                     /locus_tag="VH800_001661"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1701..1773
                     /locus_tag="VH800_001662"
     tRNA            1701..1773
                     /locus_tag="VH800_001662"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1734..1736,aa:Ala,seq:tgc)
     gene            2072..4974
                     /locus_tag="VH800_001663"
     rRNA            2072..4974
                     /locus_tag="VH800_001663"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5060..>5154
                     /gene="rrf"
                     /locus_tag="VH800_001664"
     rRNA            5060..>5154
                     /gene="rrf"
                     /locus_tag="VH800_001664"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1462 a         1062 c         1481 g         1149 t
ORIGIN      
        1 agacgaacca aacgtgaggg tgatatggag acatattacc cgtcaagaaa cgagaaataa
       61 atctgtcagc gacagaagga acgagtaagt tcaaacgcaa attaaagaga gtttgatcct
      121 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gagaactggt
      181 gcttgcaccg gttcaaggag ttgcgaacgg gtgagtaacg cgtaggtaac ctacctcata
      241 gcgggggata actattggaa acgatagcta ataccgcata agagagacta acgcatgtta
      301 gtaatttaaa aggggcaatt gctccactat gagatggacc tgcgttgtat tagctagttg
      361 gtgaggtaaa ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
      421 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
      481 tgggggcaac cctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
      541 tctgttgtta gagaagaatg atggtgggag tggaaaatcc accaagtgac ggtaactaac
      601 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
      661 tccggattta ttgggcgtaa agcgagcgca ggcggttttt taagtctgaa gttaaaggca
      721 ttggctcaac caatgtacgc tttggaaact ggagaacttg agtgcagaag gggagagtgg
      781 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
      841 ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
      901 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt aggccctttc cggggcttag
      961 tgccggagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1021 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1081 aagaacctta ccaggtcttg acatcccgat gcccgctcta gagatagagt tttacttcgg
     1141 tacatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     1201 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttaagttggg cactctagcg
     1261 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     1321 gacctgggct acacacgtgc tacaatggtt ggtacaacga gtcgcaagcc ggtgacggca
     1381 agctaatctc ttaaagccaa tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     1441 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     1501 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctatta
     1561 ggagccagcc gcctaaggtg ggatagatga ttggggtgaa gtcgtaacaa ggtagccgta
     1621 tcggaaggtg cggctggatc acctcctttc taaggaaatg gaacacgttt atcgtcttat
     1681 ttagttttga gaggtcttgt ggggccttag ctcagctggg agagcgcctg ctttgcacgc
     1741 aggaggtcag cggttcgatc ccgctaggct ccatcaggat acaatcctac taaacttaat
     1801 acaagtgaag ttgaacacgc aactcacttc ctaggaaaat ggacaatctt cccttgtgtg
     1861 caaggcccac atggtcagat tcctaatttt ctacagaagt ttcgctaaag cgagcgttgc
     1921 ttagtatcct atataatagt ccattgaaaa ttgaatatct atatcaaatt ccacgatcta
     1981 gaaatagatt gtagaaaagt aacaagaaaa taaaccgaaa acgctgtgac tatttaataa
     2041 gttttctagt ttaaaaaaac taggttaata aggttaagtt aataagggcg cacggtggat
     2101 gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt ggggagctgt
     2161 aagtaagcgc tgatccagag atgtccgaat gggggaaccc actaactaat ggttagtatc
     2221 cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta agtagctgca
     2281 ggaagagaaa gcaaacgcga ttgccttagt agcggcgagc gaaacggcag gagggcaaac
     2341 cgaagtgttt acacttcggg gttgtaggac tgcgacgtgg gactttaaaa ggatagaaga
     2401 attacctggg aaggtaagcc aaagagagta aaagcctcgt atttaaaatt cttttgagcc
     2461 ctagcagtat cctgagtacg gcgagacacg tgaaatctcg ttggaatctg ggaggaccat
     2521 ctcccaaccc taaatactct ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgatatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtcttaatag ggcgatttag
     2761 tatcatgttg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgaggtaa
     2821 aactcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgatgtt aagtctcttg gaggtagagc actgtttggg tgaggggtcc atctcggatt
     3001 accaatctca gataaactcc gaatgccaac gagatatcat cggcagtcag actgcgagtg
     3061 ctaagatccg tagtcgaaag ggaaacagcc cagaccacca gctaaggtcc caaaataact
     3121 gttaagtgga aaaggatgtg gggttgcaca gacaactagg atgttagctt agaagcagct
     3181 attcattcaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
     3241 ggggctaaaa cagtttaccg aagctgtgga tgacacaaaa gtgtcatggt aggagagcgt
     3301 tctatgtgtg aagaaggtgt accgtgagga gcgctggaac gcatagaagt gagaatgccg
     3361 gtatgagtag cgaaagacag gtgagaatcc tgtccaccgt aagactaagg tttccagggg
     3421 aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt gtatccgatg
     3481 gccaacaggt tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa
     3541 ctaaaccgga cgattggaag agtccggcta agcagtgagg tgtaagatga gtcaaatgct
     3601 tatctttata acattgagct gtgatgggga gcgaattgta gtagcgaagt tagtgatgtc
     3661 acactgccaa gaaaagcttc tagcgtttaa tgatactcta cccgtaccgc aaaccgacac
     3721 aggtagtcga ggcgagtagc ctcaggtgat cgagagaact ctcgttaagg aactcggcaa
     3781 aatgaccccg taacttcggg agaaggggtg ctgacttagg tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagggttta gcgcaagcga agatctgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac
     4081 tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc
     4141 atggagcttt actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga
     4201 gccattgact tcgggacgcc agtttcgaat gaggcgttgt tgggatacta cccttgtgtt
     4261 atggctactc taacccagat aggttatccc tatcggagac agtgtctgac gggcagtttg
     4321 actggggcgg tcgcctccta aagagtaacg gaggcgccca aaggttccct cagattggtt
     4381 ggaaatcaat cgcagagtgt aaaggtataa gggagcttga ctgcgagagc tacaactcga
     4441 gcagggacga aagtcgggct tagtgatccg gtggtaccga atggaagggc catcgctcaa
     4501 cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg
     4561 gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt
     4621 tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc
     4681 ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac
     4741 cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct gggtagctat
     4801 gtagggaagg gataagcgct gaaagcatct aagtgcgaag cccccctcaa gatgagattt
     4861 cccatgattt tatatcagta agagccctga gagatgatca ggtagatagg ttaggagtgt
     4921 aagtgtagcg atacatgtag cggactaata ctaatagctc gaggacttat ccaaaaagaa
     4981 atattgacaa cgttacggat tcttgttaga ctatagatat tcaattttga gtgggttatg
     5041 aaaatagcac atttacaagt taagtgacga tagcctagga gatacacctg tacccatgcc
     5101 gaacacagca gttaagccct agaacgcctg atgtagttgg gggttgcccc ctgt
//
LOCUS       DAUGJR010000067         4814 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUGJR010000067 DAUGJR010000000
VERSION     DAUGJR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4814
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.067"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            61..1257
                     /locus_tag="VH800_001665"
     CDS             61..1257
                     /locus_tag="VH800_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8362712.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
     gene            1510..2472
                     /locus_tag="VH800_001666"
     CDS             1510..2472
                     /locus_tag="VH800_001666"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8362713.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEIGN"
     gene            2658..3413
                     /gene="recO"
                     /locus_tag="VH800_001667"
     CDS             2658..3413
                     /gene="recO"
                     /locus_tag="VH800_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEQ8362714.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            3516..4523
                     /gene="plsX"
                     /locus_tag="VH800_001668"
     CDS             3516..4523
                     /gene="plsX"
                     /locus_tag="VH800_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEQ8362715.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            4516..4758
                     /locus_tag="VH800_001669"
     CDS             4516..4758
                     /locus_tag="VH800_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8362716.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMRDILDYLVQRLT"
BASE COUNT         1565 a          741 c          992 g         1516 t
ORIGIN      
        1 aatacttttt tttttggtaa aatataagat gtcttatcga aaaggagtag tttttttatt
       61 atgaaaaaaa gaattttatc agcagttctt gtaagtggtg ttaccctcgg agcagctaca
      121 actgtaggag cggaggattt aagtactaag attgctaagc aagattctat tatctcaaat
      181 ctgactacag agcaaaaagc tgcacagaat caagtttcag cgttacaggc tcaagtaagt
      241 tcactacaat ctgaacaaga taaactgacc gcaagaaata cagaacttga ggcgctttca
      301 aagcgatttg agcaagaaat taaggctcta acaagtcaaa ttgttgctcg taatgaaaaa
      361 ttaaaaaatc aagctcgtag tgcttataaa aacaatgaaa cttctggtta tattaatgca
      421 cttttgaatt ctaaatcaat ttctgatgtt gtaaaccgtt tagtagcaat taatagagct
      481 gtctctgcta acgctaaatt gttagaacaa caaaaagctg ataaagtttc ccttgaagaa
      541 aagcaagctg ctaaccaaac agctattaat accattgccg ctaatatggc aatggctgaa
      601 gaaaaccaaa atacattacg tactcaacaa gctaatttgg tagctgcaac tgcaaattta
      661 gctctccaat tagcatctgc tactgaagat aaagctaatt tggtagctca aaaagaagct
      721 gcagaaaaag ctgctgctga agccttagca caagaacagg ctgctaaagt taaggcacaa
      781 gaacaggctg cacaacaagc agcatctgtt gaagcagcaa aatctgctat tactccagca
      841 ccacaagcta ctccggcagc gcaaagtagt aatgctattg aaccagctgc actcacggct
      901 ccggcagctc cttctgcagg accacaaaca tcatatgatt cttctaatac ttatccagtt
      961 ggacaatgca catggggagc taaatcttta gctccttggg caggaaataa ttggggaaat
     1021 ggtggtcaat gggcttatag tgctcaagca gctggttatc gtactggttc aacgccgatg
     1081 gtaggtgcga ttgccgtttg gaacgatggt ggttatggac atgtcgccgt tgtagttgag
     1141 gttcaaagtg cctcaagtat tcgtgtgatg gagtctaact acagtggtag acagtacatt
     1201 gctgaccacc gtggctggtt taatccaaca ggtgttacat ttatttatcc acactaacat
     1261 attatttagg ttagaacagt tgttctaacc tttttgatta ctcctattgt ggaatagttc
     1321 tgagagtatt gacgatatag ttaatttata agagagttgt ttggccaatc gcttatgtat
     1381 aatataagag aagtatataa agtcgataaa aggtatattt aatacattct ttaacggttt
     1441 ttcaatttca tttgataatt cacttgaaaa gcgttaaaat ggtataggat taaaactttg
     1501 gaggaaaaaa tgtcttattc tgatttaaaa ttgtttgctt tatcgtcaaa caaggaatta
     1561 gcagaaaaag ttgcgtctgc aatgggtatt caacttggaa agtctacggt tcgccagttt
     1621 tcagatggtg aaatccaagt aaatattgaa gaatcaattc gtggtcatca tgtctttatt
     1681 ttgcaatcaa ctagctcacc tgtcaatgat aatttaatgg aaattttgat tatggtcgat
     1741 gctttaaagc gtgctagtgc tgaaaaaatt tcagttgtga tgccttacta cggctatgca
     1801 cgccaagacc gtaaagcgcg ttctcgtgaa cctattactt caaaattagt tgctaatatg
     1861 ttagaagttg ctggtgtaga tcgcttatta acggttgatt tacatgctgc tcaaattcaa
     1921 gggttctttg atattccagt tgatcacttg atgggtgcac ctttaattgc agactatttt
     1981 gatcgtcatg gtttagtggg tgaagatgtt gtcgttgtta gtcctgacca tggtggtgtg
     2041 actcgtgcgc gtaaattagc acaattcctc caaacaccaa ttgcaattat cgataagcgt
     2101 cgtagtgtgg ataagatgaa caccagtgaa gtgatgaata ttatcggaaa tgtttcgggg
     2161 aagaaatgta tcttgattga cgatatgatt gataccgcag ggactatttg ccatgcagca
     2221 gatgcgcttg ctgaagcggg ggcaacagct gtgtatgcgt catgtacgca tcccgttctt
     2281 tctggaccag cacttgataa tattcaacgt tcggctatcg aaaaactaat tgttcttgat
     2341 actatttatc tgccaaaaga acgccttatt gataaaattg aacaaatttc aattgctgat
     2401 ttggttgcag aagcgattat tcgtattcat gaaaaacgtc cgttgtcacc tttatttgag
     2461 ataggcaatt aaacttaacg aagcctgaga taatagatct cgggcttttt gacttgaata
     2521 aaatgtaagg gtaatgtggt attaattatt gtgggatgaa ctatgcaatt ctaaaggatt
     2581 ttgggtataa taagaaagat aacaacagtt tattgtaaac taagataaaa ggtaagagaa
     2641 aaatacgacg aggtaatatg caactaacag aatcactagg catcgttctt tttaatagga
     2701 attatcgaga agatgataaa ttagtcaaaa tatttactga agtagcaggt aagcagatgt
     2761 ttttcgtgaa acatattagt cgttccaaaa tgtcctcaat cattcaacca ctaacgattg
     2821 ctgattttat tttcaagtta aatgatacag gcttgtctta tgttgttgac tatagtaacg
     2881 ttaacactta tcggtatatt aataatgata tttttcgatt agcctatgct agttatgtct
     2941 tagcattagc tgatgctgcg attgcagata atgaatcaga ttcgcatttg tttacgtttt
     3001 tgaaaaaaac acttgatttg atggaagagg gcctagatta tgaaattttg acaaatattt
     3061 ttgaaattca gatattagat cgttttggta ttagtctaaa ctttcatgag tgtgccattt
     3121 gtcatcgcac tgatttaccg cttgattttt cccatcgttt ttcagctgta ctttgttctg
     3181 aacattatta caaagacaac cgacgtaatc atttagatcc aaatgttatc tacttgttga
     3241 gtcgatttca aaaaatcaca tttgatgatt tgagaactat ttcattgaat aaagacatca
     3301 aaaagaagct tcgtcagttc attgatgagt tgtatcacga ctatgtagga atcaaattaa
     3361 aaagtaaaac attcattgat aatttagtta agtggggaga tattatgaaa tgatagggtc
     3421 tctttcgttt atgggaattg gtttcagaat atgctataat aaaaatatta ttaatagatt
     3481 gtgtaagaac acaagatata attaaaggag tggaaatgaa gagaattgca atagatgcta
     3541 tgggtggaga taacgctcct aaagctattg ttgagggtgt taatcaagca atagaagcat
     3601 tttcagatat cgaaattcaa ctttacggtg atcagacaaa gattaactcc tatcttattc
     3661 aatcagatcg tgttgctatt attcatacag atgaaaaaat tatgtcagat gatgaacctg
     3721 caaaagctgt tcgccgtaaa aagaaggctt caatggtttt agcagctaag gcagtgaaag
     3781 aaggaaaagc agatgccatt atttcagcag ggaatacagg tgctctttta gctgtaggtt
     3841 tgtttgttgt ggggcgtatc aagggagttg atcgtccagg attattatca actattccca
     3901 cagtaaccgg attaggattt gatatgttgg atcttggagc taatgctgaa aatacggcaa
     3961 aacatttaca tcaatatgct attttaggct ctttctatgc taagaatgta cgtgggattg
     4021 ctaatccacg tgttggtcta ttaaacaatg gtacagaaga aacaaaagga gatccccttc
     4081 gtaaggccac ttatgaactt ttaacagcag ataatacaat atcttttgtt ggtaatgtcg
     4141 aggcgcgaga acttatgtca ggtgttgcag atgttattgt atcagatggt ttcacgggaa
     4201 acgcagtgtt gaaatcaata gaaggaacag ctattagcat tatggggcaa ctgaaacaga
     4261 taattaatag cggcggtatt aagactaaaa ttggagctag tctacttaaa agtagtcttt
     4321 acgagatgaa gaagactctt gactactcta gtgctggagg tgcagtttta tttggtttaa
     4381 aggcacctgt tgtaaagtct catggttcta gtgatgtaaa agctattttt tcaacgataa
     4441 aacaagtacg tacgatgcta gacactaacg tggtcggaca attagtagaa gaatttgcta
     4501 aggagactca agtaaatgac tagacaggag atttttgaaa ggctgattaa cttaattcag
     4561 aagcaaagaa gctatttgag tgtagctatt acagaacaaa cacatttaaa aaatgattta
     4621 gcggttgact ctattgaact agttgaattt attattaatg ttgaagatga atttcatatt
     4681 gctattcctg atgaagatgt tgaggatatg gtatttatga gagacatttt agattattta
     4741 gttcagcgtt tgacttagtt agaataataa aaagagcgta agctcttttt attattcttt
     4801 aaaaacgaac cttt
//
LOCUS       DAUGJR010000068         4663 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUGJR010000068 DAUGJR010000000
VERSION     DAUGJR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4663
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.068"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            97..486
                     /locus_tag="VH800_001670"
     CDS             97..486
                     /locus_tag="VH800_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEQ8362717.1"
                     /translation="MTKKELFENFQKNWMRLLSPFEIEDIDKWIDEDNMPVEVVNEAL
                     KETVIYNAPNLRYLNRVLNNWKRQGIDTVEKVEFARLQFENKKLSQNKNQQSNVPSWS
                     NPDYKEPDLKEFALGSMDGIEDGSGDF"
     gene            467..700
                     /locus_tag="VH800_001671"
     CDS             467..700
                     /locus_tag="VH800_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362718.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKNGVKP
                     IFNWINLYAFGTGMTTAEADRLRIERYKQENVL"
     gene            697..837
                     /locus_tag="VH800_001672"
     CDS             697..837
                     /locus_tag="VH800_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362719.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            846..1052
                     /locus_tag="VH800_001673"
     CDS             846..1052
                     /locus_tag="VH800_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362720.1"
                     /translation="MTPEQAEKAKIRAKQELETFSIYLDQAIDELGGVLTSREVFLAA
                     GITYLGAGQTDIHAAVEGLCEQIQ"
     gene            1108..1437
                     /locus_tag="VH800_001674"
     CDS             1108..1437
                     /locus_tag="VH800_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362721.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNKKDVLAYNVELTDSIQLASF
                     LPEEAYNIQKEKIDNLAETLGCDVVVIEASYDLKFIDGEDVPELTKEQKVKSMVNGMF
                     EQVFGGE"
     gene            1440..2369
                     /locus_tag="VH800_001675"
     CDS             1440..2369
                     /locus_tag="VH800_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEQ8362722.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIEEDNQDST
                     ISTPKDITPQEANSLDDLIGHQNENKDAPNNLKDVTEDLHDEEEKTLADENKTALEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLMP"
     gene            2366..3163
                     /locus_tag="VH800_001676"
     CDS             2366..3163
                     /locus_tag="VH800_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEQ8362723.1"
                     /translation="MTKLDLLGKDYYSRESAIKYWSISQYKRFRECEARALAELRGGW
                     TDTRDNTALLVGNYVHSYFESKAAHEEFKAQNDSEMISTRGTTKGQLKKDYLVAEQMI
                     EALKNDSNFMAIYQGEKEAAITGFLGEVEFKGKIDCLNVERGYFVDIKTTKGPIDDTI
                     WNREERVRWFEAYGYILQMAAYKTMLEAKYNKPFKPIIYAVTKETPPDTRAIRIQNVD
                     AMQNELDDLAQNIKHLDDVKKGLEKPKPCGHCEYCRANQLTQRVMIF"
     gene            3173..3340
                     /locus_tag="VH800_001677"
     CDS             3173..3340
                     /locus_tag="VH800_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362724.1"
                     /translation="MTKYYVSAKIANLDIGAETEAENQHMAPIAFKETYDHLLRFGSH
                     KLIILGVEELN"
     gene            3518..3859
                     /locus_tag="VH800_001678"
     CDS             3518..3859
                     /locus_tag="VH800_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362725.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGSLTMQWDFISGFKKIDDE
                     PSLDEDGELFETAYDLILAAKPKTKINLTSSYFAKEHKKDIDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            3856..4368
                     /locus_tag="VH800_001679"
     CDS             3856..4368
                     /locus_tag="VH800_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362726.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSKSYFERGRY
                     MASQLRLIQSRALKKYDCYFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKYWKFSYKDRSKKSMKLQSKIKVEQEFNKSVKDDEADAILIGSYYVNQGY
                     LDELETHDYY"
     gene            4452..>4663
                     /locus_tag="VH800_001680"
     CDS             4452..>4663
                     /locus_tag="VH800_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362727.1"
                     /translation="MTEEQMIDCLLYELVKKDKAIKKKSIIIAALTVMLIVVSGLCVS
                     LKSYYEPQIYGLRTQLSRTQKQLKRA"
BASE COUNT         1723 a          781 c          984 g         1175 t
ORIGIN      
        1 aacgtaacac taataattac taacttataa ataaatacta aataacaata aatactaaca
       61 gataataaga tgatgctgct agaagggagt cgataaatga ctaaaaaaga actttttgaa
      121 aattttcaga agaattggat gaggcttctt tcgccgtttg aaatagagga tatcgataaa
      181 tggatagatg aagacaatat gcctgtagaa gttgttaatg aagcgttgaa agaaacagtt
      241 atatacaacg caccgaacct tagatactta aacagagttc taaacaattg gaagcggcaa
      301 gggattgata cagtcgagaa agtcgaattt gctagattgc aatttgagaa taaaaagctc
      361 agtcaaaata aaaatcaaca atccaacgtc cctagctggt ccaatccaga ctacaaagaa
      421 ccagatttaa aagaatttgc tctaggaagc atggacggta tagaagatgg atcaggagat
      481 ttttaatttt tttaacaaac aaatcaaaaa agattttggt aaaacggcga gtaaagagac
      541 ttttgctaag tttgctagtt actgcgccga aggaatcgaa aaaaatggag ttaagccaat
      601 ttttaattgg ataaacctat acgcttttgg aaccggtatg acaacagcag aagcagaccg
      661 attaagaata gagcgatata aacaggagaa tgtgttatga caaaacagca tagagaaacg
      721 cttatctggt acagagcaag ccatcaagag cgtgagagat tgcttgattt cgggcttgtt
      781 gataaatcac agtacatgac actattgcgg caattgcgca agaaatatgc gatttaggag
      841 aaaatatgac accagaacaa gcagaaaaag caaaaatcag agctaaacaa gaacttgaaa
      901 cgtttagcat ataccttgat caggcaattg atgagctcgg tggagttcta acttcacgag
      961 aagtcttttt agcagcggga ataacatatc ttggcgcagg tcagacagat atacatgctg
     1021 cagtcgaggg attatgtgag caaatccaat gattttaaat ttagtgaaga ctgggagagc
     1081 aactaaaaca caggaagagg aaatgaaatg aacatcaaag aaaaaattgt agtgctaaga
     1141 aacactgaag acggaagttt tttaaagagt ttcaaaaaca aaaaagatgt acttgcttat
     1201 aatgtggaac ttacagatag cattcaactg gcatcatttt taccagaaga agcttacaac
     1261 atacaaaaag aaaaaattga taatttggca gaaacgcttg ggtgtgatgt tgtagttatc
     1321 gaagcatcat atgacctaaa atttattgat ggcgaggatg ttccagagtt aacaaaagag
     1381 caaaaagtta aaagtatggt aaacggaatg tttgagcagg tttttggagg tgaatagaga
     1441 tggcaaatca attatcaaca tacacacaca aacaattttt taacgcacca acaattcaaa
     1501 aagcttttga tgacgtttgg aaaggcgccg ggacacagtt cgcagtaagc atcttgtcag
     1561 tactacaagg tagtcaaagt ttgaaatcgg catctaatga atctatttat gcagcagcta
     1621 tgaaagcagc cgtgttaaat ctgcctattg agccaagctt aggaagggcc tatttagttc
     1681 cgtacaaagg tcaagcacaa ttccaattag gctataaagg gttgattgag ttagctcagc
     1741 gcagcggaca atacaaaaat attaatgcag gtatcgtcta taaatcacaa ttaatttctt
     1801 acaacccttt gttcgaggaa ttaatccttg actttagcaa gccacaagat gaaattgtag
     1861 ggtattttgc cgcttttaaa cttttaaatg gattcgagaa agtttctttt tggacagtag
     1921 aaaaagtaac tgcacatgga aagaaatttt caaaatcgtt tgctagcggt ccttggaaaa
     1981 cagactttga tgcaatggct caaaaaacta ttttaaaaga tattttgagt aaatatggtc
     2041 cgttatcagt tgagatgcag aaagctatcg aggaagataa tcaagattca acgatttcta
     2101 ccccaaaaga cattacccca caagaagcaa atagccttga cgacctaatt ggtcaccaga
     2161 acgaaaataa ggatgctcct aacaatttaa aagacgtaac tgaagattta catgacgaag
     2221 aagaaaaaac gctcgcagac gaaaataaga cggctttaga agatacgtct tatccggctg
     2281 atgaaatccc tgatttcgac caagagacag gcgaaattaa agctagcgaa ggcaacctct
     2341 ttgataacct tggggactta atgccatgac gaagttagac ttgctcggaa aggactatta
     2401 tagccgtgaa tcagcgatta aatactggtc cattagtcag tacaagcgtt ttagagagtg
     2461 cgaggcaagg gcgcttgctg aattacgagg gggttggaca gataccagag ataacactgc
     2521 gctgctcgtc gggaactatg tccactctta ctttgagagt aaagcagctc atgaagaatt
     2581 caaagcccaa aacgactctg aaatgatttc gaccagagga acaactaaag gtcagctcaa
     2641 aaaagactat ttagtcgcag aacagatgat tgaagcactt aaaaatgaca gtaacttcat
     2701 ggccatatac caaggagaaa aagaagcagc aatcacagga tttcttggcg aggttgaatt
     2761 caagggtaaa atcgactgct tgaatgttga acgtggctat tttgtagaca tcaaaacaac
     2821 aaaagggccg attgacgaca caatctggaa tagagaagag cgtgtcagat ggtttgaagc
     2881 ttatggatat attttgcaga tggctgctta caaaaccatg ctagaagcta aatacaataa
     2941 gccgtttaag ccgattattt atgcagtgac taaagaaacg ccgccagaca cgagagccat
     3001 cagaatccaa aatgtagatg ctatgcaaaa tgagttagac gatttagccc aaaacatcaa
     3061 gcatttagat gatgttaaaa aaggcctaga aaaacctaag ccttgcggtc attgcgagta
     3121 ttgtagagcc aatcaattaa cacaaagagt aatgattttt taggagatag aaatgactaa
     3181 atactatgta tcagctaaga ttgcaaattt agacattggt gcagaaactg aagcagaaaa
     3241 tcaacacatg gctccgatag cgtttaaaga aacgtacgac catttactta gatttggaag
     3301 ccataagctg ataatattag gcgtcgaaga actcaattaa caacctattg caaagtgaag
     3361 ctcgaccttt gcagtatcaa tattttccga gtgagaaagg aaagttggaa tatcgtcaag
     3421 ttaacaggat cgatgatatg aagaattgct acactcgtcc ttgccaatgc tcacacacaa
     3481 ttttagggcg agtgtggatt ttaaaaaggt gaaaaatatg gaacaaatca aaattacagg
     3541 aacaggaaca gcactaattt tagatagagt aaaccgaatc tttgccatct ctggcagttt
     3601 gactatgcaa tgggatttta ttagtggttt taaaaagatt gacgacgaac cgtcacttga
     3661 tgaagatgga gagttattcg aaacagccta cgacctcatt cttgcagcta aacccaaaac
     3721 taaaatcaat ctaacatctt catactttgc taaagagcac aagaaagaca tagacgaaat
     3781 cataaaagta ttctcattta tcgaagataa caagagaaat atctttgaaa cccttggcat
     3841 tcgcggggtg cttgaatgag caatctagtt ttatcgttag acatctcaac atctggaaca
     3901 gggtgggcct tatttaaagg ctcagatctt atccagagtg gtgtcttaaa acataagagt
     3961 aaatcctact ttgagcgcgg ccgctatatg gctagtcaat taaggctaat ccagtcacga
     4021 gcattaaaaa aatacgattg ctattttagt acaatcgcag tcgaaaaaaa ctcggttatg
     4081 ggacctaacc agcaatccat gcttaaaatc ggtattgtta caggaattat cttaggaaga
     4141 ttaatagctg ataacgtcgt gtttatcaat gtatcaacgt ggcgtaagta ttggaagttt
     4201 agctacaaag accgaagcaa gaagtccatg aaattacagt caaaaataaa agtggagcaa
     4261 gaatttaata aatcggtcaa agacgacgaa gcagacgcta ttttgattgg ctcatactat
     4321 gtcaatcaag gctatcttga tgaattggag acacatgact actactaaaa acgaagcgat
     4381 gcggtttatt agacagctag agttagctag cggcaagcgc gtaaacgagt actacatgaa
     4441 ggggtaaacg gatgactgaa gaacagatga ttgattgctt gctttatgag ttagtaaaaa
     4501 aagacaaagc aatcaaaaag aaaagcatca ttatcgctgc actaacagtt atgctgattg
     4561 tcgtatcagg gctttgcgta tcgcttaaaa gctattatga accgcaaata tacggactac
     4621 gtacacagct aagcaggaca caaaagcagc ttaaacgtgc gag
//
LOCUS       DAUGJR010000069         4644 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUGJR010000069 DAUGJR010000000
VERSION     DAUGJR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4644
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.069"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..407
                     /gene="tilS"
                     /locus_tag="VH800_001681"
     CDS             <1..407
                     /gene="tilS"
                     /locus_tag="VH800_001681"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8362728.1"
                     /translation="SFKITKIVPKTELVKEEKMLEYDSNLCYRDYYFSFMPKSNEDQG
                     QVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQDEQI
                     IFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG"
     gene            412..954
                     /gene="hpt"
                     /locus_tag="VH800_001682"
     CDS             412..954
                     /gene="hpt"
                     /locus_tag="VH800_001682"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEQ8362729.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            976..2955
                     /gene="ftsH"
                     /locus_tag="VH800_001683"
     CDS             976..2955
                     /gene="ftsH"
                     /locus_tag="VH800_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEQ8362730.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGNVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            3280..>4644
                     /locus_tag="VH800_001684"
     CDS             3280..>4644
                     /locus_tag="VH800_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8362731.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYG"
BASE COUNT         1546 a          669 c          904 g         1525 t
ORIGIN      
        1 tctcttttaa aattacaaaa atcgttccta agactgagtt agttaaagaa gaaaaaatgt
       61 tagaatacga tagtaactta tgctacagag attattattt ttcatttatg ccaaaaagta
      121 acgaagatca aggacaggta agtatacctt tatttagttt atcgtctatt aaattaagaa
      181 gtcgccaatc tggagattat atttcttttg gtcacttttc aaaaaaaata agacgtttat
      241 ttatagatga aaaattcaca atagctgaac gtcaaaatgc tattattgga gagcaagatg
      301 agcagattat atttgtattg ataggtaata aaacttattt gagaaaagct tgtaaacatg
      361 atataatgtt ggctaaactg tatattgata aattagaaaa agggtgacag catgctcgag
      421 caagatattc aaaaaattct ttactctgaa aatgatatta ttcggaaaac taaaaaatta
      481 ggagaacaat taacaaaaga ttatcaagaa aaaaatccgc ttatgattgg tgtattaaaa
      541 ggatcagttc cttttatggc agaactaatg aaacacatcg atactcatgt tgaaattgat
      601 tttatggtag tatcaagtta tcatggcggt acatctagca gtggtgaagt taaaatttta
      661 aaagatgtag ataccaatat tgaaggaaga gatatcataa ttgttgaaga tattattgac
      721 accggtcgca ccttaaaata tttacgagat atgtttaagt accgtaaagc taatactatc
      781 aaaattgcaa cactgtttga taaacctgaa ggtcgtgttg ttaaaattga agcagattat
      841 gtttgttaca atattccaaa tgaatttatc gtaggctttg gtttagatta cgcagaaaat
      901 tatcgcaatc ttccttacgt aggtgtatta aaagaagaag tctattcaaa atagaaaaag
      961 gtcaatgttt actgtatgaa aaataataaa aataatggtt ttgttaaaaa ttcttttata
     1021 tatatattga tgattattgt tgtcatcaca ggatttcaat tttatcttaa gggaaccagc
     1081 acacaaagcc aacagattag ttattccaaa ttaattaaac atcttaaggc tggagatata
     1141 aaatctttaa gttatcagcc tagcggtagt attattgaag ttaaagggaa atatgagaaa
     1201 cctcaaaaag tgacagttaa ttcaggacta tcatttttag gtggaagagc ttcaacacag
     1261 gtaacagagt tctcatcttt agtattacct agtgatacca tcttgaaaga aatgacagca
     1321 gcagctgata aaaatggaac agagcttaca gttaagcagg aaagttcaag tggtacttgg
     1381 attaccttct taatgagctt tttacctatt gttatttttg ctgctttcat gatgatgatg
     1441 atgaatcaag gtggtggagg agctcgtggt gctatgagtt tcggcaaaaa taaggcaaaa
     1501 tctcaatcaa aaggtaatgt taaagtgaga tttacagacg ttgctggtgc cgaagaagaa
     1561 aaacaagaat tagtagaagt tgttgatttt ttgaaaaatc ctaaaaaata taaatcacta
     1621 ggagcacgga ttccagcggg agttcttcta gaggggcctc caggtactgg taaaacatta
     1681 ctagctaaag ctgtagcagg tgaagctgga gtgccatttt tcagtatttc aggttcggat
     1741 tttgtcgaaa tgtttgtcgg tgtaggtgct agtcgtgttc gttctttatt tgaggatgct
     1801 aaaaaagctg agcgtgcgat catctttatc gatgaaattg acgctgtagg tcgtcgtcgt
     1861 ggtgctggca tgggaggcgg taacgatgaa cgagaacaga cccttaacca attactcatt
     1921 gaaatggatg gttttgaggg taatgagaac attatcgtta ttgctgcaac taaccgtagt
     1981 gatgttttag atccagcttt actaagacca ggtcgttttg atcgtaaggt tttagttggt
     2041 cgccctgatg ttaaaggacg tgaagccatt ttacgtgttc atgctaaaaa taaaccactt
     2101 gcaaatgacg ttaatttgaa agtagtagcc caacagactc caggttttgt aggtgctgat
     2161 cttgaaaatg ttttaaatga agctgcgttg gttgctgctc gcagaaataa aattaaaatt
     2221 gatgctagtg atattgatga agctgaagat cgtgttattg ctggaccatc aaagaaagat
     2281 cgcactattt cgcaaaaaga gcgagaaatg gttgcttatc acgaagctgg tcatactatt
     2341 gttggtttag ttttatctaa tgcgcgtgta gttcacaagg taactattgt acctcgtgga
     2401 cgagcaggtg gttatatgat cgctcttcca aaagaagatc aaatgcttct ttctaaagaa
     2461 gatctgaaag agcaattagc aggattgatg ggtggtcgtg ttgctgaaga aattgttttt
     2521 aatgctcaaa catcaggtgc gtcaaatgac tttgagcaag ctactcagat agcaagggcc
     2581 atggttacgg aatatggtat gagtgaaaag cttggaccag ttcaatatga aggtaaccat
     2641 gcgatgatgc caggacagat ctctcctgaa aaagcttact ctgcccaaac agctcaaatg
     2701 attgatgatg aggttcgtga actcttaaat caagctcgta atcaagcagc tgatatcatc
     2761 aatgagaatc gagatactca taaattgatt gctgaagctc ttctcaaata tgaaactcta
     2821 gacgctgcac aaattaaatc aatttatgaa actggtaaaa tgccagttga tttagaaact
     2881 gatgataatg aagctcatgc gttatcttat gacgaaatta aaaataaaat gacagaatct
     2941 gaatctgcag aatgatataa aaaagctgaa cttatagatt aagttcagct tttttatcaa
     3001 cacaatatcc ttgtaaacgt tatgaattgt aataggtgcc taattgctag aaatgagaag
     3061 atgacatact ttttttcttt attacttaaa gtgagaaaga ctttggtatt taaaactaga
     3121 aaattgttaa agccatttga aaaatctatt agtgttttct tagaataata gaagaacaga
     3181 agatagcaaa agtttcagtc aaccaataag atgaaattta caatcattac taactatgat
     3241 acacttagta gaaaatcatt tactatagaa ggtgataaca tgactatttt tcgtaaaaaa
     3301 aagaaatatt ccaataaaac agaaatgcaa aggcacttca aagttattga tttagttttt
     3361 ttaggcctag gttcaatggt tggaacaggt atctttacag ttactggcat aggcgctgct
     3421 aagtatgcag gtcctgcttt aacaatatcg attatcattt ccgcgattgc tattggaatt
     3481 ttagccttat tttatgcaga atttgcgtct cgtatgcctt ctaacggtgg tgcttatagt
     3541 tatgtttatg caaccttggg agagtttcca gcatggcttg ttggctggta tattattatg
     3601 gaatttttaa cagctatatc tagtgttgct gttggctggg gaagttattt aaaaggatta
     3661 cttgccaatt ataatatagt attaccaaac gctttaaatg gcacgttcaa tcttaagaat
     3721 ggaacttaca tagatattct tcctgtttta gtgatgtttt tcgtgacagg gattgtccta
     3781 atgaattcga aattagccct gagattcaat agttttttag ttattttaaa attttcagca
     3841 ctggctttat ttatctttgt aggcattttt tttattgatc acaataattg gtctcatttt
     3901 gctccatatg gtgtaggaca aattactgga ggtaaaacag gtatctttgc tggtgcttct
     3961 gttatgttct ttgcattttt aggatttgaa tctatttcaa tggcagttga tgaagtgaaa
     4021 gaaccacaaa aaacaatccc taaaggcatc attttatctt tgattattgt aacagcactc
     4081 tatatagttg tcaccactat tttaacggga attgtacact acactaaatt aaatgttcca
     4141 gacgcggtgg cttttgcttt aagaaatatt agactttatt gggcagctga ctatgtgtcg
     4201 atagttgcta ttttgactct tattacggta tgtatttcta tgacctatgc attagctaga
     4261 acaatttaca gtattagtag agatggttta ttacctaaat cactttatac tctcactaaa
     4321 aaaaataaag tgcctcaaaa tgctactctt gtcactggac tacttgctat gatttgtgcg
     4381 ggaatatttc ctttatcgag tctagcagag tttgttaata tttgtacttt agcatattta
     4441 attattctgt cgggtgcaat tattaaactc agaagaatag aaggagaacc aaaagcaaat
     4501 gaatttaaaa ctcctctagt accattccta ccaatgttgg caattatcat ttgtctatca
     4561 tttatgagcc aatataaagc ttttacttgg attgcttttg ctattgccac aattattgga
     4621 acattaatct acttagctta tggt
//
LOCUS       DAUGJR010000070         4413 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUGJR010000070 DAUGJR010000000
VERSION     DAUGJR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4413
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.070"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..1181)
                     /locus_tag="VH800_001685"
     CDS             complement(<1..1181)
                     /locus_tag="VH800_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEQ8362732.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYYCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NTGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     G"
     gene            1271..2137
                     /locus_tag="VH800_001686"
     CDS             1271..2137
                     /locus_tag="VH800_001686"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEQ8362733.1"
                     /translation="MKRIVVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQNPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            2115..2672
                     /locus_tag="VH800_001687"
     CDS             2115..2672
                     /locus_tag="VH800_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8362734.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRVPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            2806..4350
                     /locus_tag="VH800_001688"
     CDS             2806..4350
                     /locus_tag="VH800_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8362735.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
BASE COUNT         1431 a          666 c          857 g         1459 t
ORIGIN      
        1 tttccagtta ttattattct atcagattta tctaatgtaa agtttctata agagtctgat
       61 gtcgtgtaat caatcactaa atgagtaggg gttagttgat agtgaatatc agggcaattt
      121 tgttttaaaa agagagccaa ttgacgttcc cgctgtttta gataacgctt aataaagcga
      181 agattttttt gaaacatccc attttctaaa taaagagcta atgctttttg cattagtaag
      241 ttcgtgtcta aatcaatcaa tgatttttgg gttaaaaaat gaggttttaa acctgacggt
      301 aaaactagag ctccgatacg gagtgcagga aaaacactca ttgaaaaaga ttttaggtag
      361 atgattcggt gatgagtgtc ataataatga attggtggct ctttaagttt cacaaaatct
      421 cctaaataat catcttctaa aatataaacc tggtatcgtt gtgctagacg aacaatagct
      481 tccttttcct tagtgctata agaaagtccc agaggatgtg aaaatcgtga aatcgtgtaa
      541 aaaaatttaa tatcgccagt ttgaaataaa gattctaaga gttctaaatc aaggccatta
      601 aagtgtctag agatagtttg atagggtaat cctaactgag caacaatagc ttccatccga
      661 tgataagtag gcttttcaag gagaattgtt ttgcccgtat taggaaaagg catttgtgat
      721 aaaatataaa gcgcttgttg cgtcccagag gtgattaata gttggtcttt gttactgtaa
      781 acactatttt cagctaagta aagaagcaaa gcttccctta gttcttctag tccttcggtt
      841 ttgtgataat aatgaaagag gtatttgtct ttagcactta aggcctcatt taagcagagt
      901 cggaaatctt cataagccat attattataa tcttcaagac ttagattaag aacattatcg
      961 ggcatgctta cgttacccaa aacataataa ccacttttag gaacagcata aattaagtga
     1021 cgatatttta attctaaaag agcccgctga acagtatctt tgctacaata ataaacctta
     1081 cttagtaccc taattgaagg tagcttgtcc ccttttttta gtcgctgttt ctggatatct
     1141 tgttcgatat tggaaatgat tgtttgatat tttgttgtca taaattgtcc ccatacagtt
     1201 aagtgttata actattgtat cttatgcctc tttttcttac aatagttatt atagaaaaga
     1261 ggtaatagct atgaaacgga ttgttgtggc aaatgatctg gttggtgttg gtaaggtagc
     1321 cttgtctgct agtattcctt taatggcttc ttgtttgtta gagcaagttt tattaccaac
     1381 ttgcctttta tcaagccata ctggcggagg acagaaccct gtgaagcata ctacatcaag
     1441 tatattagac gtttttttaa cagattggga caacaaaaga attaagtttg acggcatttt
     1501 tataggttat tttacgacaa caagagatgg gcaaaagctg ctagaatggc tttcaagaaa
     1561 gcaacttccc ttaattttag atccaattat ggcagataat ggaaaacttt atcaaggctt
     1621 cagtcaaaaa catatagaga ttatgataaa acttactcaa aaagctgagc ttgttttacc
     1681 taatattagt gaggcttgtc tattaacaca aacagcttat ttagcaaaaa attatgatga
     1741 agaagatatt agacaggtgg ctagaaaatt agctaagctt ggacctaaac aggttgtcat
     1801 tagcggaatc tcttttgagg agggcagcat tggttttgct tactatcagt cagattcaga
     1861 tcaattaaca ttccattttg ggaagcaatt cccttaccat ttctatggta caggagatat
     1921 agcatcagct attataacag caggattcta ttatcagcta ccactaacac aaattctaga
     1981 tcttgttgtt tcatttcttg aaaaagtatt gcaaaatacc cttacattaa aaagagattt
     2041 aatcttaggt gttgcttatg aatctcattt aaattactta actaaatcgt ttaaaaagtt
     2101 gttggaggaa aaaaatgtca tctcaaaaat tagctaatta tattgaattg agtatgtatg
     2161 ccgctttaat ttttatttca gtacaagtgt tgcgtgtccc tgtcggtatg cagtttattc
     2221 atcttggcaa tgcattagtt gttattgcag tcttaatcta tggtagtaaa aaaggagctc
     2281 tagttgctag tcttggttta gggatctttg atgttttgaa cggctatgct tcagtcgttt
     2341 ggataactat cttagaatcc ttggctattt gtttaatttt gcatttggta tatgaaagag
     2401 ctatgcaatc tagtaaaaaa ccaaaagcca ttataacaat aacagttatt gctgcattgt
     2461 caaaattaac tattaacctt ataaaatact tactgttagc ttatataggt actcagctac
     2521 cactttcggt atctttttgg gtagctcttg gaaaaattgg tggtagtttc ggaacatctt
     2581 ttgtgacttt agttgctgtt cctcttttgt atcctgttat caaaaactta aaagaaaagg
     2641 ttacaatcgg acaagcaaaa agaggttttt gatacaagta ccttatcgat aaaaaagcaa
     2701 ggtacacttt tagtcaaata ttgacaaaag gttacaattt tgccataatg aaataactat
     2761 aaagccgttt tgacggcttt tttgatgaca gttaaggaag aaacgatgag tattttagaa
     2821 gttaagcagt tgagtcacgg ttttggggat cgggctattt ttgaaaatgt gtcatttcgc
     2881 ctcttaaaag gcgaacatat tggactagtt ggggcaaatg gtgaaggaaa atcaaccttt
     2941 atgagtatag tcacaggaca tttacagcct gacgaaggaa aagtagagtg gtcgaagtat
     3001 gtcactgcag gttacctgga tcaacataca gtgttggaat caggacaaac cgttcgtgat
     3061 gtcttgcgaa ctgcttttga tgagttattt aagaccgaga atcgtattaa tgagatttac
     3121 gcgtcaatgg cagatgataa agctgatatt gctgttttga tggaagaagt aggtgagctt
     3181 caagatcgtt tagaaagtcg tgatttctat actttggatg ctaagattga tgaagtagcg
     3241 cgtgcgcttg gtgttatgga ttttggaatg gagtcagatg ttacatcctt atcaggtggg
     3301 caacgaacaa aggttttatt agccaaatta ctattagaaa aacctgatat tctgctatta
     3361 gatgaaccaa ctaaccattt ggatgctgag catattgaat ggttaaaacg ctatttacaa
     3421 cattatgaaa atgcttttgt gttgatttcg catgatattt ctttcttaaa tgatgtgatt
     3481 aatattgttt atcatgttga aaatcaaagt ttagttcgct atactgggga ttattaccaa
     3541 tttcaagctg tttatgagat gaaacaatct caacttgaag cagcctatga acgtcaacaa
     3601 aaagagattg ctaacttgca ggattttgtc aaccgaaata aggctcgggt agcgacacgt
     3661 aacatggcaa tgtctcgcca aaaaaaactt gataagatgg atataattga acttcaagct
     3721 gagaaaccaa aaccaaattt tgaatttaag caagctagaa ctcccagtcg attcattttt
     3781 caaacaaaaa atcttgtgat tggttatgat tacccattga ccaaagaacc cttaaatata
     3841 acgtttgaaa gaaatcaaaa aattgctatt gttggggcca acggtattgg aaaatctact
     3901 ttgctaaaaa gtttattagg tgttattgag cctttagaag gtcatattgt cacaggggat
     3961 tttttagaag ttggctactt tgaacaagaa gtgacaggtg ttaaccgaca aactccgcta
     4021 gaagtagttt gggatgcttt tcctgcctta aatcaggcag aagttcgagc ggcactagct
     4081 cgttgcggac taacatcaaa acatatcgaa agtcaaattc aagtactttc gggtggtgaa
     4141 caagcaaaag ttcgtttttg tttgttgatg aatcgtgaaa ataacgtgct tattttagac
     4201 gaaccaacaa atcatcttga tattgatgct aaaaatgagc tcaaacgtgc tttaaaagca
     4261 tataagggtt ctattttaat ggtttgtcat gaacctgatt tctacaatgg gtgggtaacc
     4321 gatacttggg attttagtaa gttaacctaa actattcctt aattttttac acagaaatta
     4381 ctaaaatcag taaagatata gaataaatac tgc
//
LOCUS       DAUGJR010000071         4012 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUGJR010000071 DAUGJR010000000
VERSION     DAUGJR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4012
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.071"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            250..1839
                     /gene="mga"
                     /locus_tag="VH800_001689"
     CDS             250..1839
                     /gene="mga"
                     /locus_tag="VH800_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Mga"
                     /protein_id="HEQ8362736.1"
                     /translation="MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISML
                     TLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFR
                     DFNSLEELAEELFVSLSTLKRLIKKTNAYLMHTFGITILTSPVQVSGDEHQIRLFYLK
                     YFSEAYKISEWPFGEILNLKNCERLLSLMIKEVDVRVNFTLFQHLKILSSVNLIRYYK
                     GHSAVYDNKKTSQRFSQLIQSSLEFQDLSRLFHLKFGLYLDETTIAEMFSNHVNDQLE
                     IGYAFDSIKQDSPTGCRKVTNWVHLLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDI
                     TANYLFFDYKKSYLNFYKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFIT
                     WENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYVGEFFSITNFNELDALTIDLEEIE
                     KQYDVIVTDVMVGKSEELEIFFFHKMIPEAIIDKLNAFLNISFADSLPLDKPINPLDF
                     HRKEVILPTPPNKLHAPPSTT"
     gene            2024..3478
                     /gene="emm"
                     /locus_tag="VH800_001690"
     CDS             2024..3478
                     /gene="emm"
                     /locus_tag="VH800_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein"
                     /protein_id="HEQ8362737.1"
                     /translation="MAKNNTNRHYSLRKLKTGTASVAVALTVLGAGFANQTEVKANGD
                     GNPREVIEDLAANNPAIQNIRLRHENKDLKARLENAMEVAGRDFKRAEELEKAKQALE
                     DQRKDLETKLKELQQDYDLAKESTSWDRQRLEKELEEKKEALELAIDQASRDYHRATA
                     LEKELEEKKKALELAIDQASQDYNRANVLEKELETITREQEINRNLLGNAKLELDQLS
                     SEKEQLTIEKAKLEEEKQISDASRQSLRRDLDASREAKKQVEKDLANLTAELDKVKED
                     KQISDASRQGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLD
                     ASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQ
                     LAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQL
                     PSTGETANPFFTAAALTVMATAGVAAVVKRKEEN"
     gene            3667..>4012
                     /gene="sic"
                     /locus_tag="VH800_001691"
     CDS             3667..>4012
                     /gene="sic"
                     /locus_tag="VH800_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement-mediated lysis inhibitor Sic"
                     /protein_id="HEQ8362738.1"
                     /translation="MNIRNKIENSKTLLFTSLVAVALLGATQPVSAETYTSRNFDWSG
                     DDWSGDDWPEDDWSGDGLSKYDRSGVGLSQYGWSKYGWSSDKEEWPEDWPEDDWSSDK
                     KDETEDKTRPPYG"
BASE COUNT         1508 a          733 c          779 g          992 t
ORIGIN      
        1 aaaagagcat aaatggcata aaaaatgggt aaaaatccaa tttttgggtc acgttttata
       61 atatgtttta taaataatga acaaaaagaa ataaatgcgt gatcgtgact gttttttgga
      121 ttttaatgaa agaatttgaa aggcatttta tggtatactt tttcttaata taggtcgtac
      181 tgacttaacg aaatacctca cgaaataaca agaaaatcaa gaaaattaaa aagaagggta
      241 tacaaggtaa tgtatgtaag taagttgttt acaagtcaac agtggagaga actaaaatta
      301 atctcatacg taacagaaaa cgctgacgcc attggcgtca aagataaaga actcagcaaa
      361 gctctcaaca tctccatgtt aacattgcaa acatgtctca ctaacatgca atttatgaag
      421 gaagtgggag gaattaccta taaaaatggt tatattacaa tctggtacca tcaacattgc
      481 ggtttgcaag aagtctatca gaaagctctg agacactctc aatcatttaa attgctggag
      541 accctttttt tcagagactt caactctttg gaagaattag ctgaagagct ctttgtgagc
      601 ctttcaacac tcaagcgtct catcaaaaaa accaatgcct atttgatgca tacctttggt
      661 attactattt taactagtcc cgtacaagta tcaggagatg aacaccagat tcgactattt
      721 tacctcaagt atttttcgga agcctataaa atctcagagt ggccttttgg ggaaatccta
      781 aacttaaaga actgtgagcg gctactcagt ttaatgataa aagaggtcga tgtgagggtt
      841 aattttacat tatttcagca ccttaaaata ctaagctcag ttaacttgat tcgttattac
      901 aagggacact ctgccgtcta cgacaacaaa aaaaccagtc aacgtttttc tcagctcatc
      961 caatcatcct tagaattcca agacctttca cgcttgtttc acctcaaatt tggactatac
     1021 ctagatgaga ctaccatagc tgagatgttc tctaatcacg ttaatgacca attagaaatc
     1081 ggttatgcgt ttgatagcat caaacaagac tcaccaacgg gctgtcgaaa agtgaccaac
     1141 tgggttcatc tccttgatga gttagaaatc aggctcaatc tcagcgtcac caacaaatac
     1201 gaagtagctg tcatccttca taacactacc gtattgaaag aagaagatat cacagctaat
     1261 tacctatttt tcgattacaa aaaaagttac ctcaactttt acaagcaaga acaccctcat
     1321 ctttataaag catttgtagc aggtgtagaa aaactgatgc gttcagagaa agaacctatc
     1381 agcacagagt tgactaacca attgatctac gcctttttca tcacttggga aaatagtttc
     1441 ctaaaagtaa atcaaaaaga tgaaaaaatt cgtcttctgg tgattgaaag aagttttaac
     1501 agtgttggta atttcctaaa aaagtacgtc ggagagtttt ttagcatcac aaacttcaat
     1561 gagctagatg ctctgaccat cgatctagaa gagattgaaa aacagtatga tgtgatcgtg
     1621 acagatgtta tggtaggaaa aagcgaagag ctagaaattt tctttttcca caaaatgatt
     1681 ccagaagcga ttattgacaa gctcaatgcg tttttaaaca tcagctttgc agacagcttg
     1741 ccactagaca aacccatcaa ccccttggac tttcatcgca aagaggttat cttacccact
     1801 ccccccaaca agttgcatgc ccccccctcc acaacttaga cagcctaact gtagcaactc
     1861 aaaaacagat tcatcattaa tagcatttag gtcaaaaagg tggcaaaagc taaaaaagct
     1921 ggtctttacc ttttggcttt tattatttac aatagaatta ttagagttaa accctgaaaa
     1981 tgagggtttc ttcctaaaaa atgatagcat aaggagcata aaaatggcta aaaataacac
     2041 gaatagacac tattcgctta gaaaattaaa aacaggaacg gcttcagtag cggtagcttt
     2101 gactgtttta ggggcaggtt ttgcgaatca aacagaggtt aaggctaacg gtgatggtaa
     2161 tcctagggaa gttatagaag atcttgcagc aaacaatccc gcaatacaaa atatacgttt
     2221 acgtcacgaa aacaaggact taaaagcgag attagagaat gcaatggaag ttgcaggaag
     2281 agattttaag agagctgaag aacttgaaaa agcaaaacaa gccttagaag accagcgtaa
     2341 agatttagaa actaaattaa aagaactaca acaagactat gacttagcaa aggaatcaac
     2401 aagttgggat agacaaagac ttgaaaaaga gttagaagag aaaaaggaag ctcttgaatt
     2461 agcgatagac caggcaagtc gggactacca tagagctacc gctttagaaa aagagttaga
     2521 agagaaaaag aaagctcttg aattagcgat agaccaagcg agtcaggact ataatagagc
     2581 taacgtctta gaaaaagagt tagaaacgat tactagagaa caagagatta atcgtaatct
     2641 tttaggcaat gcaaaacttg aacttgatca actttcatct gaaaaagagc agctaacgat
     2701 cgaaaaagca aaacttgagg aagaaaaaca aatctcagac gcaagtcgtc aaagccttcg
     2761 tcgtgacttg gacgcatcac gtgaagctaa gaaacaggtt gaaaaagatt tagcaaactt
     2821 gactgctgaa cttgataagg ttaaagaaga caaacaaatc tcagacgcaa gccgtcaagg
     2881 ccttcgccgt gacttggacg catcacgtga agctaagaaa caggttgaaa aagatttagc
     2941 aaacttgact gctgaacttg ataaggttaa agaagaaaaa caaatctcag acgcaagccg
     3001 tcaaggcctt cgccgtgact tggacgcatc acgtgaagct aagaaacaag ttgaaaaagc
     3061 tttagaagaa gcaaacagca aattagctgc tcttgaaaaa cttaacaaag agcttgaaga
     3121 aagcaagaaa ttaacagaaa aagaaaaagc tgaactacaa gcaaaacttg aagcagaagc
     3181 aaaagcactc aaagaacaat tagcgaaaca agctgaagaa ctcgcaaaac taagagctgg
     3241 aaaagcatca gactcacaaa cccctgatac aaaaccagga aacaaagctg ttccaggtaa
     3301 aggtcaagca ccacaagcag gtacaaaacc taaccaaaac aaagcaccaa tgaaggaaac
     3361 taagagacag ttaccatcaa caggtgaaac agctaaccca ttcttcacag cggcagccct
     3421 tactgttatg gcaacagctg gagtagcagc agttgtaaaa cgcaaagaag aaaactaagc
     3481 tatcactttg taatactgag tgaacatcaa gagagaacca gtcggttctc tcttttatgt
     3541 atagaagaat gaggttaagg agaggtcaca aactaaacaa ctcttaaaaa gctgaccttt
     3601 actaataatc gtctttgttt tataatgaaa acattaacga aataatttat taaggagaga
     3661 atactaatga atattagaaa taagattgaa aatagtaaaa cactactatt tacatccctt
     3721 gtagccgtgg ctctactagg agctacacaa ccagtttcag ccgaaacgta tacatcacgc
     3781 aattttgact ggtctggaga tgactggtct ggagatgact ggcctgaaga tgactggtct
     3841 ggagatggtt tgtctaaata tgaccggtct ggagttggtt tgtctcaata tggctggtct
     3901 aaatatggct ggtctagcga taaagaagaa tggcctgaag attggcctga agatgactgg
     3961 tctagcgata aaaaagatga gacagaagat aaaacgagac caccatatgg ag
//
LOCUS       DAUGJR010000072         3970 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUGJR010000072 DAUGJR010000000
VERSION     DAUGJR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.072"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..683)
                     /locus_tag="VH800_001692"
     CDS             complement(<1..683)
                     /locus_tag="VH800_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
                     /protein_id="HEQ8362739.1"
                     /translation="MEHQIERLIAEDIYIKVSFSVKQSGLIFIPNYQLDIRKEENHKK
                     YKVYIRETAQFFIYNKEASELNRYMRGHELICQLTNDSKSIPKRRRQTIDTLKKKIEE
                     ISLLIELDTENKPYQDIKDDIVKDMAQLDLTITELQDHIAHLNKVAEVLLNLNNNDIE
                     NRRLARYDYAKMNLTAAIKIEEVEKEIETSQNELNISIDEYEYLVRRLEKFGEILSDS
                     KIIDTSRNE"
     gene            complement(948..1160)
                     /locus_tag="VH800_001693"
     CDS             complement(948..1160)
                     /locus_tag="VH800_001693"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362740.1"
                     /translation="MMTDRVVKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLL
                     NRANSLEELLLKAKEVNLTIDLKQKM"
     gene            complement(1206..1480)
                     /locus_tag="VH800_001694"
                     /pseudo
     CDS             complement(1206..1480)
                     /locus_tag="VH800_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(1471..1796)
                     /locus_tag="VH800_001695"
                     /pseudo
     CDS             complement(1471..1796)
                     /locus_tag="VH800_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            complement(1971..2570)
                     /locus_tag="VH800_001696"
                     /pseudo
     CDS             complement(1971..2570)
                     /locus_tag="VH800_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            complement(2869..3234)
                     /gene="rplL"
                     /locus_tag="VH800_001697"
     CDS             complement(2869..3234)
                     /gene="rplL"
                     /locus_tag="VH800_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEQ8362741.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(3299..3799)
                     /locus_tag="VH800_001698"
     CDS             complement(3299..3799)
                     /locus_tag="VH800_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEQ8362742.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVIVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     misc_feature    complement(3829..3964)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
BASE COUNT         1134 a          847 c          629 g         1360 t
ORIGIN      
        1 atttcatttc gagaagtatc gataattttg ctatcactca agatctctcc aaacttttcc
       61 aaccttctta ctagatattc atactcatct atggatatat taagttcatt ttgagaagtt
      121 tcaatctctt tctcaacttc ttctattttt atagctgcag tcaagttcat cttggcatag
      181 tcatatctgg ccaaacggcg gttctctata tcgttgttgt tcagattaag caagacctcc
      241 gcaaccttat tgagatgagc aatatggtcc tgcaactctg taatggtcaa atctaattga
      301 gccatatctt taacaatgtc atctttaata tcttgataag gcttattctc cgtatctaac
      361 tcaatgagga gacttatttc ttcaatcttt ttcttaagtg tatcaatggt ttgtcgtctt
      421 ctttttggaa tactcttgct atcattggtt aactggcaaa tgagctcatg ccctcgcata
      481 tagcgattaa gttcagacgc ctccttgttg taaatgaaga attgtgcggt ctcacgaata
      541 tagactttat attttttatg attttcttct ttcctaatat ccaattgata gttaggaatg
      601 aaaataagac cactctgctt tacactaaaa gacaccttga tataaatgtc ctcagcaatt
      661 aacctctcaa tttgatgttc cacaagttca acttcaaact catggatggc atctcgttgc
      721 cccttgtatt tcttgaagac ttccttactc tcttcagtgg atacctcctc tttatctcgt
      781 tcttcttgaa aagcatgtac tgtttctgta gactttctaa tcgatctgaa acaccgactt
      841 ccttattttt aaagtaatct tgaaaaaatt gacatcatat aatttcttat cgcttatttt
      901 tttatgacct aaacttatct tttgagtatc ttcttctagg ataaaagtta cattttttgt
      961 tttaagtcaa tggttagatt cacttctttt gcttttaata gtagctcctc taatgaattg
     1021 gcacggttca acaaaaattc taatcgactt tcaatttcta tcttggcaaa atgtgtacga
     1081 aaaaattctt catcatataa atctcgttta ctgagttgac ggcctcgaat tggttttttc
     1141 actactcgat ccgtcatcat gaatctgcta tgcttctgac taaaatcaat atgaacatgt
     1201 aattactctg ctttttctaa aaaatcatca aagaactttg actgctgcat caaaaaataa
     1261 agacgttgtt tcaattcaaa tttatgacta gactacctat atttttgata gtcacggtag
     1321 gaataacgct tctcgataat ttttgctcca gtcatttttg aaatacggtc tgaaatcata
     1381 cggaggtttc gttccaaggc ataattccat atcaattttt tatctgaatt acggtcaatg
     1441 gcgttgattg gatgtgatta tgggtatgat ttttatctgt ttggtcgctc gagtaatctc
     1501 aaagaagaga gttctcctag tgccctcaaa tcccagtcgt ctgcctgcga gtgaaaatgc
     1561 ttgacaaggg aaaaaccacc gcagatgata tccacttgcc ctctaagttg tctaaagtct
     1621 tggtctgtga cttgtctaat gtcatgaaat tctatttctc cttcggtctc atagatggct
     1681 ttgtaagatt gcctcgcaaa cttatcaatc tcacaaaagc caatacactc atggcactga
     1741 ttaattaaac ccaatcgaaa gcctccaatt cctgcaaaca aatctaaaaa cttcatatct
     1801 ctcattcctt tctgacaaaa taaaaggacc ttactgctta tgtaacgtcc ttactcaact
     1861 ataatcttcc atttctggtg cagtgataac ttcaataatc aaccaaattg tccttagtcc
     1921 ccaaacacct aataatagcc accaaaacat cttactcact tcgcttcttg tcaccttagt
     1981 tgcttggtcc attcggataa gacaccatta aagacatatt ccgcaatagc ttcagctgtt
     2041 cttgcgaacc gtatgtgttc cagcgcataa gcatagcgtt cttcaaaata gctcatgact
     2101 aagtcactag cagcttgtga taaaccacct tcacgtaatt gggaatgaac caaactccaa
     2161 atataatctt tgtcatattt ggtgacctga tcaacttgac gggtaaagtg accctcagtc
     2221 tttttcacac tagtgcactc ctttctttcc tcctcgtcct caatcactaa attactctct
     2281 ttagtttcac taccttcagt ttcactcttt tcagtctcac taggggctga atttaacacg
     2341 gggctggtct gtttttgaga ctggccccgt ctgaacttaa gactggggtg aaatcatgtt
     2401 ccaactttcc taaataaatc ttattagcca aacgcccttt ttcactggga gactgttgga
     2461 cttcatcgat caaaccatag tctcgtaggt tttcttaatc gctaacaatt tcgacttgga
     2521 acagccaagg agtactgtca ttttgagttg gaataaatga gatagatggc aatcaccatt
     2581 tgtcgtgatg actgttcatt catttgcatg attttcctcc tgaaaataaa aaaatgagaa
     2641 cacttattaa aatgttctcg ttcacataaa aaaattatta ctagacacat atagatagaa
     2701 taaccactct actcagctta atttttatag aaaataaaaa tcctgccaaa gattttttgg
     2761 gcaggatttt tggcaagaaa ccaaatcaat ttatcagttt cttcaaatcg ctataaactc
     2821 taaaagactg ataaatcggg atttcgctct caaattgcta tctgcttctt atttaagagt
     2881 gattgttgct ccagcttctt caagtttagc tttgatttct tcagcttctg cagcagcaac
     2941 gccttcttta acgttagcag gtgctccatc aacaagacct ttagcttctt taagaccaag
     3001 acctgtgatt tcacgaacag ctttgataac gccaactttt ttgtcgccag cagatgtcaa
     3061 ttcaacgtcg aatgaatctt tagcagcttc ttcagcacca ccagcagctg cagcagctac
     3121 aggagcagct gcagttacac caaattcttc ttcgatagct tttacaagat cgttaagctc
     3181 aaggattgaa gcttctttaa tttcagcaat aatgttttca atgttcaatg ccattgtgat
     3241 ttcctccaaa taattaattt aaaatgttaa gcgtagcctt aagctactct gagacgactt
     3301 aagcagcgcc ttctttgttt tctgcaacag ctttgacagc gtatgcaacg ttacggactg
     3361 gagcttgaag tacagaaaga agcatagaaa gcattccttc gcggtttggc aatgttgcaa
     3421 gtgcttggat ttcttctttt gaagaaacag cgccttcgat tgcaccacct ttgatttcaa
     3481 gtgcgtcagc agttttagta aagtcgttga taactttagc tggtgcgata acatcttcgt
     3541 tagaaaatgc tactgcagat ggtcctacga atacatcttt caactcatca agacctgctt
     3601 tttcagctgc acgagtcaaa attgagtttt tgataacttt gaactcaacg ccactttcac
     3661 gaagtgaacg acgaagaaca gtatcttgat caactgtaag accacgtgaa tcaacaataa
     3721 cgatacttgc tgctgctttc attttctcag caataagttc gacttgttca gcttttttag
     3781 caataattgc ttcactcatt agttttacct ccgtttttat ttttgggcta ggtacaaaaa
     3841 aaatcgcacc taaacctaga cacgaaagta caaatacgtt attttcttta atcacgtttt
     3901 gtgcctcggc aggaatatta tgagcatgct cccctgctgt cttaggtcag ttttttatca
     3961 aaacctatat
//
LOCUS       DAUGJR010000073         3657 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUGJR010000073 DAUGJR010000000
VERSION     DAUGJR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3657
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.073"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            26..217
                     /locus_tag="VH800_001699"
     CDS             26..217
                     /locus_tag="VH800_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362743.1"
                     /translation="MPDNTIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            229..945
                     /locus_tag="VH800_001700"
     CDS             229..945
                     /locus_tag="VH800_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEQ8362744.1"
                     /translation="MNQIINITVNDNHEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQVEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRANGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            977..1243
                     /locus_tag="VH800_001701"
     CDS             977..1243
                     /locus_tag="VH800_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362745.1"
                     /translation="MEEKKFFTTYEMDLMNSVVTLQKSILTQTEHLSDQLTKKLHHLE
                     DYNSPIDDEAIRLAEVTAEFYKLLIKSPSVGATVKEIVSEGHKR"
     gene            complement(1178..1984)
                     /locus_tag="VH800_001702"
     CDS             complement(1178..1984)
                     /locus_tag="VH800_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HEQ8362746.1"
                     /translation="MLNIDTQFVDTIGKILSDYVSHSEITRMGEVLGYPQNDQNSGFN
                     KHKRVHNLMSDILNRTQNTDNIKLVIEYVCNPLRYINEVSIFEQLRTAINIPLSLKGL
                     IVSDSGQIVTTTTSKTLSEAKKRFETLDSRLKELKVHPHVLKFCTQELLQENYFHAVF
                     EASKGVFHRIRLLTGSAMDSASLIDQCFKPGEPIVIINGNKLQTLDEQSEYKGLKNLL
                     LAIAHLYRNSKAHKLKYYNPDNLNDALTALTLMSLAHNLLDSCSNTRRLD"
     gene            complement(2126..2365)
                     /locus_tag="VH800_001703"
     CDS             complement(2126..2365)
                     /locus_tag="VH800_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362747.1"
                     /translation="MDTKEFMKVVSKHINQNFNVDNQLVEFVVAELNQMNAPITQKQA
                     QHIVNILEYVSKSTSKSTIAAMTNALLELGVLKGD"
     gene            2532..2717
                     /locus_tag="VH800_001704"
     CDS             2532..2717
                     /locus_tag="VH800_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8362748.1"
                     /translation="MWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKFD
                     DVVKIADVLGVSLDEFR"
     gene            2795..3106
                     /locus_tag="VH800_001705"
     CDS             2795..3106
                     /locus_tag="VH800_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEQ8362749.1"
                     /translation="MPKAEITYRAVDVNETASHGDYKHLIQQWEGLTVATAKQWATEM
                     RDHPDFKQFVLNPTHRIVFIDYEGFKLFVQWKSRNRYKTKKETLSEMLENIKFEKRVG
                     A"
     gene            3108..3293
                     /locus_tag="VH800_001706"
     CDS             3108..3293
                     /locus_tag="VH800_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362750.1"
                     /translation="MNKLELFLLVTTIILAIITRVQHEVIKKHNSPENKRRIFREVAL
                     ENSKGWREKRSGGKVVS"
BASE COUNT         1310 a          580 c          725 g         1042 t
ORIGIN      
        1 tatttttgaa aaaggaggta tacaaatgcc cgataacaca atcgccatcg aaaaaattaa
       61 aaagtatttg cttgataaca accttaaaca agttgatcta gcagttactt atggcaaaga
      121 accgcaagat gtggcgaaca ttcttgctgg acgaaaaaaa gacccagcat caaatcgctt
      181 tgttttaaaa gttatttcag atttaaaaat cagatagaaa ggcatcaaat gaatcaaata
      241 atcaatatta cagtaaacga taaccatgaa ccagttgtca gtggtcggga cttgcacaaa
      301 gtgcttgaaa ttaaaacagc ttataaagat tggtttccaa gaatggccga atatggcttt
      361 gaagaaggtc aggactttag ctcatttttg agcaaaagta caggaggtcg ccctagtcaa
      421 gaccatgtac ttaaactaga catggctaaa gaaattgcga tgttgcaacg gaatgaaaaa
      481 tcaaagcaag tccgcaaata ctttattcag gtcgaaaagg actttaatag tcccgagaaa
      541 atcatggcaa gagccctgct gatggcagac aagaaagtac ataaattaga ggctcagatt
      601 gaggctgacc gtccaaaggt gctatttgct gatgctgtaa gtgctagcaa atcatcttgt
      661 ctgattggtg agctagctaa aatcctgaaa cagaatggga tcaatattgg tcagaataag
      721 ctatttcagt ggttacgagc caacggctac ctaatcagtc gccgcggtga gtcttggaat
      781 cagccaacgc aaaaaagtat gcaacttgga ttgtttgaac tcaaaaaaac agccatcaat
      841 cactctgatg gtcacactac aacaaatgta accccaaaag ttactggtaa ggggcaacaa
      901 tactttatta ataaattcct taatcaggaa tatctaccag tttagaaacg taacaaaact
      961 aacgaaggga gaaaatatgg aagagaaaaa attttttact acatatgaaa tggatctgat
     1021 gaattcagtt gtaactcttc aaaaatcaat cttaacgcaa acggaacatt tgtcagatca
     1081 actaacaaaa aagcttcatc acctagaaga ctacaatagt ccgattgatg atgaagcaat
     1141 tagattggct gaggtaacag cagaatttta caagttgtta atcaagtctc ctagtgttgg
     1201 agcaactgtc aaggagattg tgagcgaggg acataagcgt taaggccgta agagcgtcat
     1261 tgagattatc tggattgtag tatttgagtt tgtgagcttt agagttgcga taaaggtgag
     1321 cgattgcaag tagcaaattt tttaatccct tatactcact ttgttcgtct agagtctgca
     1381 atttattacc gttgataatc acaatgggtt ctccgggttt gaaacattga tctatcagac
     1441 tagctgagtc cattgctgag cccgttagta gacgaatacg atgaaaaaca cctttacttg
     1501 cttcaaatac ggcatgaaaa tagttttctt gtaagagctc ttgagtgcag aattttaaaa
     1561 cgtgagggtg tacttttaat tcttttaacc tactatcaag tgtttcgaag cgttttttgg
     1621 cctctgataa agtttttgaa gtagtagtag taacaatttg tccgctatct gatacaatca
     1681 aaccttttag cgagagcgga atgttaatgg cggttcttaa ctgttcaaaa attgaaactt
     1741 cattaatgta tcttaaagga ttacagacgt attcaatcac aagttttata ttatctgtat
     1801 tctgtgtcct atttaatata tcggacatga gattgtgcac ccgtttgtgc ttgttaaatc
     1861 cagaattttg gtcgttttgg ggataaccta aaacttcgcc cattcgggtt atttcagaat
     1921 gcgaaacata gtcagatagt attttaccga ttgtatcaac gaattgggtg tcaatattta
     1981 acataacaaa cctcgttttt atttaaatta taccacagaa aggagaacca catgagacca
     2041 aaacgatatc cgtatagcgg agagaaaaag agagcctatc ataagataga ccctgaactg
     2101 ataaaaaccg gtaaagttga ttgcatcaat ctcccttaag tacgccaagc tctaacaatg
     2161 catttgtcat agctgcgata gtagatttag aggttgactt agagacatac tccaaaatat
     2221 taacgatatg ctgagcttgc ttttgtgtaa taggtgcatt catttgatta agttccgcaa
     2281 cgacaaattc aactaattgg ttgtcaacat tgaaattttg gttgatatgt tttgagacaa
     2341 ctttcataaa ttcttttgta tccataatta atctcctttc ttgcttattt gactaaacaa
     2401 gattagaaga atagaggtct ctcgagagat cttgttgaat catacgaata ttatatcaag
     2461 actatattga aaaatcaata tattgtatat aaaaagttat caacaactac atgttgtgct
     2521 taggaggaat tatgtggggt aaaatcgaag ctctattaat tgagaaaaaa atgaccaaat
     2581 atgaactgtc acaaaaggct ggattgaacc aaaattgctt gattgatcta aagaaaggaa
     2641 gaaaaaaatc attgaaattt gatgatgtcg ttaaaatcgc cgatgtctta ggtgtcagct
     2701 tggacgaatt cagataacaa aaaaagtccg acggcaatcg gactcaaaac tagattaatt
     2761 tacttaatta taccacaaga gagaggatat taatatgcca aaagcagaaa ttacttatag
     2821 agcagttgat gttaatgaaa cagcttctca tggtgattat aaacacttga ttcaacaatg
     2881 ggaggggttg acagttgcta ctgcaaagca gtgggcgaca gaaatgcgtg atcatccaga
     2941 ctttaaacag tttgtattaa atccaacgca tagaatcgta ttcattgatt acgaaggatt
     3001 caaactgttt gtacagtgga aatctcgcaa tcgttataaa acaaaaaaag agacactgtc
     3061 agaaatgctt gaaaatatta aattcgaaaa aagagtagga gcataacatg aacaaattag
     3121 aactattttt attagtaaca acgatcatct tagcaatcat cactagagta caacacgaag
     3181 tcattaaaaa acataattcg ccagagaata aacgcagaat ttttagagaa gtggctttag
     3241 aaaacagcaa agggtggaga gagaagcgtt ctggaggaaa ggtggtcagc tgatgcagta
     3301 catttttcaa aaatacgaca agtagctata catccgttag caacgaattt atagatgatt
     3361 gtgaattatc cctaaaatca aaaggcctgc ttatggtaat tcttagaaat aaagaagatt
     3421 ggagagtata tccagaggaa ttggctagaa ggtccagaga tagcgtgaga gttgtaagga
     3481 cttgcttaga agaattagag agagtcggat atgtgagaac ttacagaaaa tctttagggc
     3541 gagggaaagg catacaatat tatagatttt gctcagataa aaagatatcc gaacaagcat
     3601 ttaaaaaaat gattagtgat tttacaactt aacgttttac aaagttgtat tttacaa
//
LOCUS       DAUGJR010000074         3243 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUGJR010000074 DAUGJR010000000
VERSION     DAUGJR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3243
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.074"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..914
                     /locus_tag="VH800_001707"
     CDS             <1..914
                     /locus_tag="VH800_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8362751.1"
                     /translation="EENYSQEIPTRIKNLRKKHNITQSELGNAGQVSQVESGKRPITS
                     SMLVYLNALTASNYTYIVFGELDEFIENLFHYFFSSILYRDLEAVDENLYSFMSDDLI
                     SIQSSCLSIAKTFANFNIQRKRFMISTETEMDTFHKKDDIDVWVGGKSYNPARSFRNN
                     PINELTVIDFEEMADILLLMLRDNLIRSFEINVCNTLFELDKNGEPTTFNLDKIDSII
                     NKWWSENVSTEIIPNLIKKLRENPLFNIGFMVNDILERMYKEDIPKSYLTSVPLVISK
                     KARSTLSIKSNGSQKIDKSKFAQILSL"
     gene            980..1732
                     /locus_tag="VH800_001708"
     CDS             980..1732
                     /locus_tag="VH800_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8362752.1"
                     /translation="MAIPDLDKFSSNLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPKSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            1729..2331
                     /locus_tag="VH800_001709"
     CDS             1729..2331
                     /locus_tag="VH800_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362753.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(2807..3088)
                     /locus_tag="VH800_001710"
     CDS             complement(2807..3088)
                     /locus_tag="VH800_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8362754.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR"
     gene            complement(3095..3145)
                     /locus_tag="VH800_001711"
                     /pseudo
     CDS             complement(3095..3145)
                     /locus_tag="VH800_001711"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
BASE COUNT         1081 a          607 c          530 g         1025 t
ORIGIN      
        1 ttgaagaaaa ttattcacaa gaaataccta ctcgtatcaa aaatttaaga aaaaaacaca
       61 atattacaca aagcgaacta ggcaatgcag gtcaagttag tcaagttgaa agtggtaagc
      121 gaccaattac gagttcgatg ttagtttatt taaatgctct aaccgcttcg aactatacgt
      181 atatcgtttt tggagagtta gatgagttta ttgagaatct gtttcattat tttttcagtt
      241 ctattttata tagagattta gaggctgtag atgaaaacct atattctttc atgagtgatg
      301 atttaatttc aatccaatca agttgtctaa gtattgccaa gacatttgca aatttcaata
      361 ttcaaagaaa aagatttatg atttctactg aaactgaaat ggatactttt cacaagaaag
      421 atgacattga cgtatgggtt ggtggaaaaa gttataaccc cgctaggagt tttaggaata
      481 atccaataaa tgaattaact gttattgatt ttgaagaaat ggctgatatt cttttgttga
      541 tgttgagaga taatctaatt aggtcgtttg aaattaatgt ctgcaacaca ctgttcgaat
      601 tagataaaaa tggtgaaccg acaacattta atctagataa aattgactca ataatcaata
      661 agtggtggtc tgagaatgtc tcaacagaga taatacccaa cctcataaaa aaacttagag
      721 aaaatccctt gtttaatatc ggatttatgg taaatgatat attagaacga atgtataaag
      781 aggacatacc aaagtcttac cttacttctg ttccattagt tatttccaaa aaagcaaggt
      841 caactttatc gattaagtca aacggaagtc aaaaaataga taaatcaaaa tttgcacaga
      901 ttttgtccct ttagagacgg atgacttaca cattcaacgt ggattattct tcccttggag
      961 aaaggggatt tcagaacgct tggcgattcc tgatttagat aaattttcat ctaacttaca
     1021 acaggggaaa attcctgtca taaagcactt cgaactcaat ttagataagg ggagtcactg
     1081 ggctattgct ggaaattcag gttctgggaa accgtacgct ctcacttact tcttgagtgt
     1141 cctgaaacct aagtccggcc taattatcat tgacccaaaa ttcgataccc ctagccaatg
     1201 ggcaagagaa aataaaattg ccgttatcca cccagtagaa aaccattcaa aatctgattt
     1261 cgtttcacaa gtcaatgaac aattaaacca gtgtgcaact ctcattcaga aacgacaagc
     1321 tatcttgtat gataatccca atcatcaatt tacccatcta actattgtta ttgatgaagt
     1381 cctcgctcta tcagagggag tcaataagaa tatcaaagaa gcttttttct ccctactatc
     1441 acaaattgcc ttgttgggac atgctactaa aatccatcta ttcttgggaa gccagcgttt
     1501 tgaccataac actattccca tttcagtgag ggaacagcta aacgtattat tgcaaattgg
     1561 aaatatcaat cagaaaacca ctcaattctt atttccagac ctagatccag agggaattgt
     1621 cattccaaca ggacacggaa caggtatcat tcaagttgtc gataatgaac actcctatca
     1681 agttctaccc ttactctgtc caacctacta tactaagcga ggtatcctat gaccactaaa
     1741 acctacttca tgagaagctt caatctcata ttatacttac tgcttattgc tccaatctgc
     1801 tatgtgttcg gttggctgtt caatcttgtt tcagttcaat tatctaccgt cacatttgtc
     1861 aatctggata cggttaaaaa cgttactgat accattagtt ctgtatgtta tggattcgct
     1921 cttatttctt tacttctagc cttattatct ggattaaaga tgatacaacg cttgaataca
     1981 gatagccttg ggaactactg ccaatctatt tatcgcacct ttctattaag acacttcctt
     2041 ttccagcgtg aacgagtaca gaaggtaagc aactttgaac accagaccgt taccactatc
     2101 aatccaatcc ataacgggtt taaccgagct gtacgtaagt gtatcgtaga tatacgaaaa
     2161 gatgccatta ctgtatttct aaaagttcct agagaccaac aggggcaaaa aatcctaaag
     2221 gatacgggag tacaactgaa agaagagatt gtcatccaac acacagacta ttatttctct
     2281 tctcctgttc gagttcgtaa ccaattgtgg tttattggtc aaaagcgtta attccttggg
     2341 gctgtggctt gcgttaagca aaagccagac agcccctttt ttatattctt atctatcatg
     2401 acctattggg gttactacga caacgaaagt tagaagctgt gggtatttat ttatcttgaa
     2461 aagattgctg aactaacgca ataactactc taccattcac tctacctttt attaagcaac
     2521 tatcaataaa tattgataca ataaggttta taacagctaa aatagaaaat acttaacctt
     2581 tacagaagta aaataattga gatgagaaaa gcctatgaaa tgaacgtttc aaaggctttt
     2641 ttcgtgttta aaaaaacaaa tgaaaaaaca aaatagagag tagggttatt aacactgtca
     2701 gtcctgtgta cgcaataaca atccatgctt tttgataagg atattttgct ttttctttaa
     2761 tcttatcaat ctgatctaag ctctcaccct ttgctatagc ttcaagttat cggtaagtct
     2821 gaacatcata tgtcttttta aatcgctcaa ttcttaaggc gatacgcatg attatcaacc
     2881 ataagatagc aaccggacca tatccccacc aacctaacca agacattata ggataaatac
     2941 tgatagcaat taggagtgtc ccaaataaca taatatgcgt attcctatca cattgtttaa
     3001 tctcctcatc cttaataatt aaagtcattt ttgggatatc ttctgctatt agttgctcta
     3061 aaggaacctg taaggactta cttaacatca aaagattttg caggtctgga tagcttttac
     3121 cgttttccca gtttgagata gtcttcttga aacatacatc atttcagcaa gctcttcttg
     3181 tgacatctgt aatttttttc aataataaga taactggttt ttaaagccca taataaatct
     3241 cct
//
LOCUS       DAUGJR010000075         2913 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUGJR010000075 DAUGJR010000000
VERSION     DAUGJR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2913
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.075"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            192..842
                     /locus_tag="VH800_001712"
     CDS             192..842
                     /locus_tag="VH800_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8362755.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            845..1513
                     /locus_tag="VH800_001713"
     CDS             845..1513
                     /locus_tag="VH800_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8362756.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            1522..2754
                     /locus_tag="VH800_001714"
     CDS             1522..2754
                     /locus_tag="VH800_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8362757.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSVMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
BASE COUNT          976 a          418 c          576 g          943 t
ORIGIN      
        1 ttatagatca agtttactat gattttgttt gtaattcaat ggtattttta aaaaataacg
       61 tacaaaaaat atatgaaagc gatttaaaaa caaacgatac agatcatttg aagttatata
      121 gttagaaata aagataaccg atcattgcag agatttaagc atttgttgag aaaatttgtt
      181 ataataagcg tatgaaagaa agactagaac attattctac cagctctata tatagcggat
      241 ttgaagtgta cttgccgttg gtactacaga caataacaga tgtgattatt gctgagaata
      301 tcaaaagcaa aaaagaaacg gggtttaaac tatacgaaca ctttacatcc cgtattaaat
      361 cggaagcttc gatgattgaa aaatgtcaac gcaaacagct tcctctaaca agcaaatctg
      421 cgttaaaaat cattaaagat agtatcggta ttcgcattat ttgtggtttt attgatgata
      481 tttatcggat ggtagacttg ctcaaaagca ttcctggtat gtcagttaac actgaaaaag
      541 attatatttt aaatgccaag cctaatggct atagatcata tcatctcatt ttggaattag
      601 aaacacattt tccagatatt ttaggggaaa aaaaaggatg ttattttata gaagtgcagt
      661 tgcgaaccat tgctcaagac tcttgggcta gcttggaaca tcaaatgaag tacaaacatc
      721 aagttgctaa tgcagaaatg attacaagag agttaaagcg ttgtgcagac gagttggcat
      781 cttgtgatgt taccatgcaa accattcgtc aattgattca agaaacgacg gaggaagagt
      841 aaccatgaaa attttgttag ctgaagacga atggcagatg tctaatgttt tgacaactgc
      901 catgactcat caaggttatg acgttgatgt ggtttttaac ggtcaagagg caattgataa
      961 agccaaagac aatgcatatg atattatgat tttagatatc atgatgccga ttaagtctgg
     1021 cattgaggct ttaaaggaga ttcgcgcttc aggaaattgc tcacatatta ttatgctgac
     1081 ggctatggca gaaattaatg accgtgttac cggactagat gcgggagctg atgattatct
     1141 gactaaacct ttctcattaa aagaactttt agctagatta aggtcgatgg aaagacgagt
     1201 agaaagtttt actcctcagg tattacaatt tgctggtgtc acattaaata ttaatgagca
     1261 agaattgagt gccggtaatg ctatacgatt agcttctaaa gaaggtaaat taatggcctt
     1321 tttaatgtta aatcaaggaa agtacttgga tactaaaacg ctttaccaac atgtttggtc
     1381 agaccaagaa gattatgata cttctattgt ttgggtttat atttcttatc ttcgtcaaaa
     1441 attattagct attcaagcaa atgtcattat tgcaggtgat aaagatacta gctattgttt
     1501 attagaaaaa taggaggtga catgtttaat cgtatccgca ttcgttttat catgattgct
     1561 tctattgcca tttttattat tttaagttca attgttggta ttattaacac ggcacgctgt
     1621 taccaaagtc aacaagaaat taaccgtatt ttacatttaa tttcctcaaa taaaggtaaa
     1681 ttacctggca ctacggaaag ctctaaacga cttggaacga aactgtctga agatagccta
     1741 agccagtttc ggtattatag tgtcattttt aatgctaatg gacatctact ttcttctaat
     1801 actgctaata tttcagcttt agatagagaa gaagcccaat attttgctag actttttgct
     1861 aagtctgggg aagaaaaagg cagttaccgt caccaagata gtgtttattc gtacttgatt
     1921 actcagctgc caaatgaaga aaaactggtt gtaattttag atactacctt ttattttcgt
     1981 agtgtaggag atttattagc tgtttcagtg atgttggcct ttggaggatt tatctttttt
     2041 gttgttttag tgagtctttt ttccggtatg gtcatcaaac cttttgtcca aaattatgag
     2101 aagcagcgtc gctttattac taatgcaggc cacgagttaa aaacaccact agccattatc
     2161 tcagccaata atgaattggt cgaattaatg actggagaat cagaatggac caagagtaca
     2221 agtgatcagg tgaagcgatt gacaggcttg attaatcaaa tgattacttt ggctcgtttg
     2281 gaggaacagc cagatgtggt attacatatg gtagactttt cagctattgc tcaagatgca
     2341 gctgaagatt ttaagagtct ggttttgaaa gatggtaaac gttttgattt gacgattcaa
     2401 ccgaatatta tgattaaagc ggaggaaaag tcattgtttg aacttgtgac aattttagtt
     2461 gataatgcca ataaatattg tgatcctaaa ggcttggtca aggtatcttt aaccactatt
     2521 ggaagaagac gaaaacgagc gaaattagaa gtttctaata cctatttgga aggaaaatcc
     2581 attgattaca gccgcttctt tgaacgcttt tatcgcgaag acgaatccca taatagcaaa
     2641 gaaaaaggtt atggaattgg tttatctatg gcagaaagta tggttaagtt atttaaagga
     2701 acgataactg taaattataa aaacgatgct attgttttta cagtggtgat ttgacttaaa
     2761 catttttcag tacctttagc tagtaataat gtctaggtaa aggtaataaa cgatgcttaa
     2821 ccagcccatg aggctggttt ttaacgttta atttagtaga agagtgatta aagaaggtag
     2881 tttgaaataa gaaaattttt gttatgatct taa
//
LOCUS       DAUGJR010000076         2645 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUGJR010000076 DAUGJR010000000
VERSION     DAUGJR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2645
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.076"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            26..640
                     /locus_tag="VH800_001715"
     CDS             26..640
                     /locus_tag="VH800_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEQ8362758.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEVPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
     gene            complement(1053..1925)
                     /gene="sdaAA"
                     /locus_tag="VH800_001716"
     CDS             complement(1053..1925)
                     /gene="sdaAA"
                     /locus_tag="VH800_001716"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEQ8362759.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKEQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIDSQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(1937..2608)
                     /gene="sdaAB"
                     /locus_tag="VH800_001717"
     CDS             complement(1937..2608)
                     /gene="sdaAB"
                     /locus_tag="VH800_001717"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEQ8362760.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMGTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
BASE COUNT          829 a          497 c          494 g          825 t
ORIGIN      
        1 acggagaaaa gtgaggtatt attgaatgtt taagaaagaa aatttaaaac aacgttattt
       61 taattttgga ttagtagcgt tagctctaac aatattagcc atcatttttg ccttctcaag
      121 taaaaatgct gatactaagt cttatgctaa gaagtcagaa agtaaaatgg taacaatcga
      181 caaggctcca aaaaataatc atgctattac taaagaagaa agcaaagaaa aagcaaagag
      241 cattgcttcg gagcctattc ccacagtaga aaactctgta gctccgacag taacagagga
      301 agtaccggtt gttcagcaag aagtgactca aactgttcag caggtatctt cagtagccta
      361 taatccaaac aatgtggtac tttccaatgg aaatactgct ggtattgtag gaagtcaagc
      421 ggcggcacag atggcagcag caacaggtgt tccacaatca acttgggaac atataattgc
      481 gcgtgaatct aatggaaatc ctaacgcagc taatgcttct ggggcatcag ggttgttcca
      541 gacaatgcca ggttggggtt ctacagcaac ggttgaagat caagtcaatg cagccttgaa
      601 agcctatagt gcacaaggtt tatcagcttg gggttactaa ataaacatgg ctggaagaaa
      661 taaaacctat tgttagtatt tactaacaat aggtttttgg tatttaattg tctttatgat
      721 ttgtagtgat gaattagtct caaaacaaaa cattgcctta tcgggaatat agctcgtatt
      781 atttaggaaa actgaccagc acttaagtgc ctctgatatt taaggcagtt atactgataa
      841 caagcaggaa aaaaactctt aaatgtttat aaggtcatta gcaattttca gtattttaca
      901 ctactacact tttgagtttt aacaatttac tagaagttgt ttctaagggg aaacaacata
      961 gcttgatagc tatctattag tcattttagt gaatatatag cagaaaaata aaacgctttc
     1021 aaatatttct aagaattttt ctaactatct atttattcgc caaatatttc tacgctgtaa
     1081 cgtcgtccag ttggagtagc ggctaaacca ccttctgctg tttcacggaa agcagttggc
     1141 atggcagagc cgacttgata catagcatca ataacttcgt caacaggaat ttgagaatca
     1201 atatcagcta aagccatatc agctgcgaca agggcgaaac ttgctcctag ggcattgcgt
     1261 ttgacacaag gcacttctac taggccggca acaggatcac agacaagtcc taataaattt
     1321 ttgataacaa acgcaatagc ttgactagct tgatgagatg ttccaccggc tgctttaaca
     1381 agagcagctg cactcatagc agctgcagaa ccaacttctg cttggcatcc accttctgca
     1441 ccagaaatag aggcgttatt tccaataaca agaccaaaag ctcctgcagt aaataaaaac
     1501 tctaattgtt ctttttctga taagtcaagt ttttcaatag ctgttgcgag cactgctggt
     1561 aagcatcctg cacttcctgc agtgggtgtt gcacagacaa gtcccatttt agcatttaat
     1621 tcgtttacag ctatagcatt tctaacagca ttaagaatag tagtatcaga aaggctgttc
     1681 ccttttttaa tgtagttatc cattttgacc gcatcgcccc ctgtcaaacc actgatagat
     1741 ttggttgagg ttagtccttc tgttacagct gctttcataa cttgtaaatt gcgtgacatg
     1801 attttgataa tatcttctcg atttcttcca gacatctcca cttccgtggc aatcatgagt
     1861 tcagcaatat ttccattaaa ttgttggtca gcttgtttga caagttcttc aatagtataa
     1921 aacatagctt tcctttctag tcaaagaagt tgacattata aatatgagga atttttgcaa
     1981 tttggttggc tgcttcttgg cactctctag aatcgacttc tataatcata gtagcttttt
     2041 caccagcgga ttcacgtgta acattcattg tggcgatatt aatattattg gaagatagga
     2101 tatcagttac ctttgcgatc attccgggaa tatctttgtg tacagtaact atagtaggag
     2161 tattcatgga taacgagaca gaaaaaccat ttagttctgt tacttgaatg tttcctcctc
     2221 caattgaaac accagtaaca ctaagtgttt tgtcagcttt tttgacactg attttaacag
     2281 tattgggatg gggagcatta ctatctttta agatatccca atagattttt atcccttttt
     2341 gatgagcaat ttctagagaa tttttaatat caggattatc agtacccata cccataattc
     2401 ctgcaacaag agccttatca gtaccatgtc ctctgtaggt tttagcaaat gaattataaa
     2461 ggtgaaacgt cacttcatca ggaatatctc caaagatgga atggactacc ttaccaattc
     2521 tgacggcacc agctgtgtga ctacttgatg gaccaatcat tactggccca atgatgtcaa
     2581 aaactgattg aaatttttgt gtattcatag gcaactccgt tttttatttc tatgtttatt
     2641 ataac
//
LOCUS       DAUGJR010000077         2548 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUGJR010000077 DAUGJR010000000
VERSION     DAUGJR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2548
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.077"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            201..935
                     /gene="cofE"
                     /locus_tag="VH800_001718"
     CDS             201..935
                     /gene="cofE"
                     /locus_tag="VH800_001718"
                     /EC_number="6.3.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ8362761.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSEFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIRGLDYKWSENTSIKEALNE"
     gene            928..1914
                     /locus_tag="VH800_001719"
     CDS             928..1914
                     /locus_tag="VH800_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ8362762.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVDFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1924..>2548
                     /locus_tag="VH800_001720"
     CDS             1924..>2548
                     /locus_tag="VH800_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8362763.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVM"
BASE COUNT          953 a          308 c          494 g          793 t
ORIGIN      
        1 tgttaacaat gatttaggaa tacattatgt agaactaggt aaaggaatta tcgattataa
       61 aacaatcatt catgaaatcc atgaacattt tatagactta atttttagtt tagaagtaca
      121 tgaaaaagaa atagacaaaa aggcagaagt agtgaggaag tcttatctga cactaaatga
      181 gtatattaat ggaggctaaa atgaatttga gtatatttgg tttaaagaat attccttatt
      241 tgaaagaagg ggatagtata gaaaagctta ttgaagaaag cattaaaact tcagaatttt
      301 ttatcgaaga caatgatgtg ctttgcatag cttctaaagt tgtatctatc gcagaaggcc
      361 aggtgatgtc tttaaacgag atacaagtga gtgatgtagc aaaagaaatc cacaggaata
      421 ttcctcgtaa agatcctaga ataattgaaa ttatgctaaa tttagtcaat agagatctgt
      481 cacgtttaga tatcaaaaaa aattacattg gttgtcgctt ggaaaatggt ttaaagttga
      541 caagtggtgg aatcgataga aaatcagtag atgaagtatt tcttttacct aataatccgg
      601 atgcttctgc aaaaagaatt tcggaatatc ttaaaaaatc acttggaaaa aatgttgcag
      661 ttgttataac agatagtgat ggtagagagg ataaaagagg tgctactcaa gtagcaattg
      721 gtatttatgg tattcatcct ttgagaaaaa cagaagtaat agattcacaa ggagagacaa
      781 taaaattcca agaagagact ttgtgtgata tgattgcagc ttgtgctggc ttagtaatgg
      841 ggcaacgtgg aactggaatt ccagctgtcc tcattagggg cttggattat aaatggtctg
      901 aaaatactag tattaaggaa gcattaaatg agtagaaatc aggactgtaa gaatattcta
      961 atcattggtt ttggaaaaat tgggaaaatt aaagcgtaca agtggctatc acgcggatat
     1021 gaggtatatg tcaaagattt gaaattctcc agcatgaaat accttaatac aaatagtgat
     1081 gtgttggatg atttatcacg acaatatttt actattgaga tttgtactcc gacaaatcac
     1141 caccttacgc tattgaaaac cgttataaca aggtatgtct attcttatat tagcattgaa
     1201 aaaccactgt gtaataggtt agaagattta gaagaaatga agtcgctagt agaaagtcac
     1261 ccacatctag caaaaaaaat ttttgccagt gaacaatact tcttttcgaa aattttggaa
     1321 aaactgttac aagtagattg tttctctcta gataaaatca aggaaataac agttgatttt
     1381 tctaaagata ggattgagga taacgagaat gggagatttt tagataaaga gatattgggc
     1441 tatggaatag agattcctca tatcattgct gtcatttctt atttaggaat ttcattagaa
     1501 gaattcaaaa aaggaatctt tgtgaatgct atttatataa aagacttaga gaaacacgat
     1561 tattcaatag aaatcttatc ttgtattaat caaacagtga ttaaaattat tagtaatttg
     1621 ggaagttttg caataagaga gggcaagatt gaaggaggtg atgctaaaac agtaagaaga
     1681 gttaccattg atgacaaaac aatactattt gatccacatc ctaaactcga gaggtataag
     1741 agtgaattgg taactgggac aaatacgttt caaatacacg atgatatgat ggacacgtat
     1801 atcagtttgt tagaaggaaa tgctattcct gaagattgct atatcaataa tgcaattgag
     1861 ataacaaaat tattaattaa cttatattca gaatgtgaaa aaatttattt atgaggtgta
     1921 actatggatt taaaaattac aaacggcttt tatgacccaa gtcatttatc atacgaagta
     1981 gtagaacgca aaggcttagg tcaccctgat accttagcag atggaattgc tgagcaaatt
     2041 gaaattgatt actcacttta ttgtttggac aagtttggtg ttattccaca tcataatttt
     2101 gataagatta ttatccgagg gggacattca gttcaggatt ttggtggaag tgactttatt
     2161 gaaccaatta aaattatttt tctaggtagg gcgagcaaaa aatgttttaa tagttcaatt
     2221 ccacttttta aaattcagaa aaaggctgca actaaatatt taaatagaat tttacctaat
     2281 ttagatgttg aaaattatgt agaatttgag acattgacct cagattttac tacaaaaact
     2341 aattggttct cgcctgaagc aatagaagat ttaccggagt atctagatgt accaaaggca
     2401 aatgatacag ctacaatgat aagttattgg ccattaacaa tttctgaaga attagcatta
     2461 atgattgaag ggtattttta taaattagat aagaatgaat taccaacgcc aagatttact
     2521 aaaatgggtg gtgatattaa agtaatgg
//
LOCUS       DAUGJR010000078         2534 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUGJR010000078 DAUGJR010000000
VERSION     DAUGJR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2534
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.078"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(298..537)
                     /locus_tag="VH800_001721"
     CDS             complement(298..537)
                     /locus_tag="VH800_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEQ8362764.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(547..819)
                     /gene="rpsP"
                     /locus_tag="VH800_001722"
     CDS             complement(547..819)
                     /gene="rpsP"
                     /locus_tag="VH800_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEQ8362765.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            complement(946..>2534)
                     /locus_tag="VH800_001723"
     CDS             complement(946..>2534)
                     /locus_tag="VH800_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEQ8362766.1"
                     /translation="QYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRII
                     ADQEISFYLFRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYL
                     PEFIVGELSKITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTK
                     KKHVLLWMKLFAINGLTIVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFF
                     TTIFFKLCSAMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTS
                     HSKTVIAHRGLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLA
                     GVNKTIRNLTLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGN
                     YVDLFLETYHRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDF
                     YVIEDFSYRSYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIK
                     DLKQDNSYFSRLVRIISSLY"
BASE COUNT          899 a          440 c          391 g          804 t
ORIGIN      
        1 atgcccccca aaaaactgag agagcatttt ttaggaaact ataaacatac aacaaacagc
       61 aggttggaaa ataaagacta tctcgtaaga tgaattgtag ctattttaca tgacagcagc
      121 tatcaaaaac cagtataatc tcttataaag gcaatcagct aagccattct ttaacttctt
      181 tttagttaaa gacagaaaaa tctaatcttt tcatttcaga aatattaaga tttttgctat
      241 tcaaaaagct tgttgacttt aagtcaacaa gcttttcaat ccatctcaag ttagtgatta
      301 tttctcatca ataactaagc gaactttttt tcctagtgtt ggaaccgagt agacaatcga
      361 tcttatcgca gtaatagttc gacctttttt gccgataaca cgaccgatgt cttgagcatc
      421 caagtcaaga tgatactcta aaaagtcagg agtatcttca attttaatgg taagattatc
      481 tggttgtgaa atcaaaggtt tcacaatagc gataataaga ttttcaatgg tatccatagg
      541 ctgttattat ttagagaatt tttggtcgtg gaacttagcc ataacaccag ctttagacaa
      601 gatgttacga acggtatcag aaggctgcgc tcctttagat aaccactcaa gaacacgatc
      661 ctctttaata gtaatttgat tttcagccac taatgggttg tatgttccaa ctgtttcgat
      721 aaaacgacca tcacgtggtg cacgtgaatc tgcaacatta atacggtaga aaggtttttt
      781 cttagaaccc atacgagtta aacggatttt tactgccatt tttaaatagt ctcttttctt
      841 ttagtaatgt ataagaaata cagctacgct aaattcctat gttaaacagt ataactcagt
      901 ttaaagaaag tgtcaagttt ttttcttgac actttcctta aacctttaat aaagactact
      961 aataattctg actaatcgac taaaataaga attatcttgt tttaagtctt taatcaattg
     1021 attagttaaa gctggttggt ctgtaataat tccctgaata ggctttagga gataatgctc
     1081 tatgcgcttg ggatcattaa tagtccaaac gtaaatttct ttattattcc aaaaagcttg
     1141 ggacgacaaa taagaccgat aagaaaagtc ttcaatgaca tagaaatcaa caaattcatc
     1201 tccaaaaaat ccaaattgaa ttggtatgat ataaccagtc gtaattgatg gatttttttt
     1261 cttgatagct tctattactt ctaaatctaa agacatgact ttattatctt tgcttatacc
     1321 aagtcgatga taagtttcta aaaacaaatc gacataattt ccaggttctg taccaattgg
     1381 cttgagttca ataagtaatg gcatattcaa cttcttagcc ttttgataaa aggtgtcaaa
     1441 agaaacaaaa cgccctgaaa aatgtccttg atgactcgtt agatgttcaa cttcttttaa
     1501 ggttaagttg cgaatcgtct tatttactcc agctaaacgc ttcaatcgat tatcatgaga
     1561 caccacaaag tgattatcct tagtcaagat tagatccagt tctacataat cacttcctgc
     1621 tttcttagca ccttcaaggg cttccagaga attttctaca cctgctgata caagtcctct
     1681 atgcgcgata actgtcttag agtgagatgt gtcaaaaaaa gttaaacgtt caagagattg
     1741 ataagcaaaa cctactgtaa ccacgataaa gattacaaca tatgccttat tacttcttct
     1801 tggctcatca tattgctttt gtggttcaat tgcctctttt aaaatcattg ctgaacagag
     1861 tttaaaaaaa atagtagtaa aaaaaatgag ttcccatgta aaggtcaaag ctcccagctg
     1921 aacaataata ttattcccct taggattaaa catatcaaca aaaataagaa tcatggaaat
     1981 agctagcgat aagactacaa tcgtaagacc attgattgca aaaagtttca tccataacaa
     2041 tacatgtttc tttttagtct tttgccaact ctctctccat gcttgagcaa ccgtacgatg
     2101 gttgattgct atcaatggta aaaaatatac taatcttagg ttaaggtaaa acacaagaat
     2161 aagactgcca taaagcaagt actttgtgct agttatcttt gataattccc caacaataaa
     2221 ttctggaaga taaagctttt gagtaatcac agaagataaa ccaatatgta agactggaat
     2281 agtcaatagg atataaagca aaaaaagtaa taattggtaa ccagaaaatg ttttccaaag
     2341 cccccttagg taataagaaa actgttttct aaaaagatag aaactaattt cttgatccgc
     2401 aataattcga tatagagcaa aaaactcaag gtgaataaaa gcagctaata aaaataaata
     2461 ggcacctaat aaagcaagtg ctataggatt ttttaaaaaa gtcacaacat tgtctttatc
     2521 taaatgatat tgac
//
LOCUS       DAUGJR010000079         2400 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUGJR010000079 DAUGJR010000000
VERSION     DAUGJR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.079"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..231
                     /locus_tag="VH800_001724"
     CDS             <1..231
                     /locus_tag="VH800_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8362767.1"
                     /translation="TDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTGGFGL
                     GLALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
     gene            complement(356..604)
                     /locus_tag="VH800_001725"
     CDS             complement(356..604)
                     /locus_tag="VH800_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEQ8362768.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(658..1578)
                     /locus_tag="VH800_001726"
     CDS             complement(658..1578)
                     /locus_tag="VH800_001726"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEQ8362769.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1813..>2400
                     /locus_tag="VH800_001727"
     CDS             1813..>2400
                     /locus_tag="VH800_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8362770.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLKTLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKD"
BASE COUNT          808 a          340 c          443 g          809 t
ORIGIN      
        1 acggacaaaa atttattaat ttctgttatt gataatggtc cagggataac agatgaagaa
       61 aagaaaaaga tttttgatcg tttttatcga gttgacaaag ctagaacacg gcaaacaggt
      121 ggatttggct tggggttggc tttagctcag caaatcgtga tgtctttaaa aggaaatatt
      181 acagtaaagg ataatgatcc taaaggtagt atttttgaag tcaaactata agctaaaaag
      241 ggcgaccaat aaggtcagcc cttttaaagt tatttttaac tgtcaacgct ttattgtatt
      301 ttttgagttt ttaccgtata aaaaaactcc agctggagtt ttcattggat atttattagc
      361 caagttttgc agcaaggcgt gctttatcgc ggcttgcttt gtttttgtga atcaaacctt
      421 ttgattcagc tttatcgatg cttgaagaag cagcgcggaa aagctcttca gatgggttag
      481 cttcaaatgc tttgatagca gtacgcatag ctgatttttg tgctgagttt ttttcgtttg
      541 ctttaacgtt aagttcagcg cgtttaatag ctgatttaat atttgccaat gttttcacct
      601 ccaaattaat ctaactacat tattatatag aaaatatatg cgtttggcaa ccctttatca
      661 ctttttgagg taaatttcat caattttatg atcagcactt ttatgtaaaa ttaattcagc
      721 acggttacgt gtaggttcaa tgaatttttc aagattttct aaattaacgg ttttccaaac
      781 gttgcgcgca aatgctatag cctcagatcg aggtaattgt gcatattggg cataataatt
      841 atgagggtca cgttttgcta attttaaaat gcttagaaac cgttcaatgt accaggtttc
      901 gatgtgactg ctgtctgcat caatataaat agaaaaatca aagtaatcac tcatatataa
      961 acgattgttt tgttgatttt gaaaaacgtt aataccttcg acgataagga agtcagggtt
     1021 attaaatgat tgtttttgat ttgggataat atcgtaaata tcatgagaat agacgggtgc
     1081 aaaagcagtt tgaccatttt tgatggaatc tagaaaatct aagagaagtt ccatgttata
     1141 agattctgga aatcctttac gatttaacag tccttgttca ataagaaact gattaggata
     1201 taaaaaacca tcagtcgtta ccagttcgac ttgactattg gggtgcgttc gtgataataa
     1261 aagttgtaaa agacgactag ttgttgattt accaacagct actgaaccag aaattccaat
     1321 aataaaaggc cttaattgaa tgtctttttt tagaaaaagg cttttagaaa aagaaagatt
     1381 ttcttgcgca attttgtaaa cctggatcag attaattaat ggaaggtaga tatcaatgac
     1441 atcgttaata ctgatgttat catttaagct agtaatactt ttaagttcct cttgtgtgag
     1501 gagagctttt gccttttgat gtaatgtttt ccaagactct ctagaaattt tttcaaagtt
     1561 aataaattca tttgacatgg tagctcctaa tcatttgaca gtgcttacat tataccattt
     1621 tagttaaaaa ataaataatt tttcgttagt atttacacga aaattaatac aattaactca
     1681 aaaaagccac acattcctag tacaattatc ctgctatatt ctaacaaata gttaaagttc
     1741 ggtttttatt tgtaatatag ataaaattgt taaaaaacaa gcgtcttgta aaccatttca
     1801 aagtatgata gaatgaaaaa gtaccttaaa aagataggaa aaatgatgac aaagatgtat
     1861 tatgatgaaa atccagatag cctacacgat attcatgaag taaaagtaga gctgcttaat
     1921 catcccttta cttttttgac ggattcaggt gtcttttcaa agaaaatggt tgatttcggt
     1981 agccaagtat tattaaagac actaaatttc aaggagaacg aacgtgtact ggacttaggt
     2041 tgcggctatg gccctcttgg gattagtcta gccaaggttc aaagggtaga cgcaacctta
     2101 gtggacatca ataatcgtgc tcttgattta gctagaaaaa atgcaactaa taaccaagtg
     2161 gcagtaacta tttttcaatc aaatatttat gaaaatatta gtggccattt tgagcatatt
     2221 attagtaatc ctcctattag agcaggaaag agagtagttc atagtattat tgaaaaaagc
     2281 atagattttt tagtggttaa tggtgactta acgattgtga ttcaaaaaaa acaaggagct
     2341 cctagcgcta aagcaaaaat ggcaactatt tttggtaatg ttgagatatt aaggaaagat
//
LOCUS       DAUGJR010000080         2140 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUGJR010000080 DAUGJR010000000
VERSION     DAUGJR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2140
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.080"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..341
                     /locus_tag="VH800_001728"
     CDS             <1..341
                     /locus_tag="VH800_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEQ8362771.1"
                     /translation="GDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGEQIHFEIW
                     NNGERFSDSTLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLNNPARGGA
                     SAIISIKKKI"
     gene            489..629
                     /locus_tag="VH800_001729"
     CDS             489..629
                     /locus_tag="VH800_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEQ8362772.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     VK"
     gene            744..1361
                     /locus_tag="VH800_001730"
     CDS             744..1361
                     /locus_tag="VH800_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8362773.1"
                     /translation="MIKAQLKNLIKTIHLVKEAGFSLNGSLYMELLHDFTHDELVHNP
                     IIESTVDTIQSVEFERVSFSYNGKDNVINDISFSIKAGERLAIVGGNGSGKSTIFKLA
                     CGLYDNYEGNIYINGINLCSIQKKSYYKRISALFQDFLKYELTLRENVGLGELSKLYS
                     DESYNTSFFTTSWDSENELRLEDIYIRYSDGKFHFTTIDESIKRD"
     gene            1443..2132
                     /locus_tag="VH800_001731"
     CDS             1443..2132
                     /locus_tag="VH800_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8362774.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIILEKEYDGSENLEEL
                     FNNQILFEKRR"
BASE COUNT          781 a          262 c          415 g          682 t
ORIGIN      
        1 atggagatga ggaaaatctg ataagagctc tttctaacct tttagttaat gcaataagat
       61 ttatgcccgt attagataaa aaaatcgaag ttatactgtc tgagtcagga gagcaaattc
      121 attttgaaat atggaataat ggtgagcgtt tcagtgatag tacactgaaa aagggagata
      181 aattatttta cacggaagat tatagcagag gtaacaaaca ttatggaatc ggtttggcat
      241 ttgttaaagg cgttgctatc aaacacggtg ggaatcttca attgaataat ccagctagag
      301 gaggtgctag cgccataatc tcgataaaaa agaaaattta atagatttga ttgaaactgg
      361 agtatttcag gcaaaaaatc gtaaattttt ggctaaaata ctttttttct gaacaaattc
      421 tgaacttggg gtgtcataat aatcatgtaa atatatcgga tgcaaaaacg taagagagga
      481 actagaaaat gaataacaca attaaagact ttgatctcga tttgaaaaca aataaaaaag
      541 acactgctac accttatgtt ggtagccgtt acctatgtac ccctggttct tgttggaaat
      601 tagtttgctt tacaacaact gttaaataat aaagttatca ttatcataaa cattataatt
      661 tcaaataatt ttatatattt ataaatttag gggagtagac tgattttagt ttgctccttt
      721 attagtagat aaggaagtta tacatgatta aagctcagct aaagaatcta ataaaaacaa
      781 ttcatctcgt aaaagaggct ggtttctccc taaatggttc attgtacatg gagttattgc
      841 atgattttac gcatgatgag ttagtacata accctataat cgaaagtacg gttgatacaa
      901 ttcagtcagt tgaatttgaa agggtttctt tttcatataa tggtaaggat aatgtaataa
      961 acgatataag tttttcaatt aaagcaggag agaggttagc aattgttggt ggaaatggtt
     1021 ctggaaaaag tacgattttc aaattagcct gcggtcttta cgataattat gaaggcaata
     1081 tatatataaa tggtattaat ctttgttcaa tacagaaaaa gtcatactac aagagaatat
     1141 ccgcattgtt ccaagatttt ttaaagtatg aattgacact gcgtgaaaat gttggattgg
     1201 gtgaattatc aaagttatat agtgatgagt cttataatac ttcatttttt accacatcat
     1261 gggattcaga gaatgaactg cgattggagg atatttatat aagatatagt gatggtaagt
     1321 ttcattttac aactatcgat gaatcgatta aacgggattg atagagagtt tgaagagaaa
     1381 gtgtattgtt ttgcttacta tacactaaac gctcagcaat atatagaatg ggagtaacta
     1441 atatgttgaa aatacaaaat ctaaaaaaat cttatggtaa gagaaccata ttgaataatg
     1501 tcaatatgaa tattcctaag ggaaaagtgt atgctttaat cggtccaaat ggtgctggaa
     1561 aatcaactat tatgaaaatt ttgacaggct tagttagtaa gacaagtggt tctattattt
     1621 ttgaaggtag agaatggtca cgtcgggatc tgcgaaaaat cgggagtatt attgaagaac
     1681 caccacttta taaaaatttg agtgcttacg ataatatgaa ggtagttaca acaatgcttg
     1741 gtgtttcaga aagcactata cttccattat taaataaagt tggtctagga aatattgaca
     1801 agagaccagt aaaacaattt tctcttggaa tgaagcaacg gttaggtata gctatctctt
     1861 taataaattc acctaaacta cttatattag acgaacctac taatggcttg gacccaattg
     1921 gaattcaaga attaagggaa attatagagt catttaaatc agaaggaatg acaattatga
     1981 tttcaagcca tatactgtca gaagttgaac atctagctga ttttattgga tttatctatg
     2041 aaggaaagat tattctggaa aaagaatatg acggctctga gaatcttgaa gagttattca
     2101 ataatcaaat tttatttgaa aagaggaggt aggggctatg
//
LOCUS       DAUGJR010000081         2104 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUGJR010000081 DAUGJR010000000
VERSION     DAUGJR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.081"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            121..1413
                     /gene="purB"
                     /locus_tag="VH800_001732"
     CDS             121..1413
                     /gene="purB"
                     /locus_tag="VH800_001732"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEQ8362775.1"
                     /translation="MLERYSRPEMAAIWTEENKYHAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDTKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
     gene            1545..>2104
                     /gene="rgg4"
                     /locus_tag="VH800_001733"
     CDS             1545..>2104
                     /gene="rgg4"
                     /locus_tag="VH800_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEQ8362776.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     LILLELYLAYLDIEGMDGQYSDKIFY"
BASE COUNT          676 a          350 c          474 g          604 t
ORIGIN      
        1 attgataaga gcgaaggaag agttataccc agaagcttat ccagctaata tatttaaaaa
       61 tggtaaacgt actaaagaat taaaagaaaa aatgtctttt taataagata aggggaaaaa
      121 atgctagaac gttattcacg ccctgagatg gcggcaattt ggacagagga aaataaatac
      181 catgcttggt tggaggtcga gattttggct gacgaggcat gggctgagtt gggtgagatt
      241 cctaaggagg atgtggctaa gattcgtgag aaggcggatt ttgacattga ccgcattctt
      301 gaaattgagc aggacacgcg tcacgatgtg gtggctttca cgcgtgcggt ttctgaaacg
      361 cttggtgagg agcgcaagtg ggtgcactac ggtttgacct cgactgacgt ggtggacact
      421 gcctatggtt acctctacaa gcaagctaac gacattatcc gtcgcgatct tgagaatttc
      481 accaatatcg tggcagacaa ggcgcgtgag cacaaaatga ccatcatgat gggtcgtacc
      541 cacggtgttc acgccgagcc aacgactttc ggtcttaagt tggcgacttg gtacagcgag
      601 atgaaacgta atattgagcg ttttgaacat gctgccgcag gtgtggaagc tggtaagatt
      661 tcaggtgccg ttggtaactt tgccaacatc ccaccttttg tggaagaata tgtctgtgac
      721 aaattaggca ttcgtccgca agaaatttca acacaagttc ttccacgtga ccttcacgca
      781 gaatattttg cagtgcttgc aagtattgca acttctatcg aacgtatggc gacagagatt
      841 cgaggtctgc aaaagtcaga acaacgtgaa gttgaagaat tctttgccaa aggtcagaaa
      901 ggtagctctg ctatgcctca caaacgcaac ccaatcggtt cagagaacat gacagggcta
      961 gcgcgcgtga ttcgtggtca catggtgaca gcttatgaga acgtgtcact ttggcatgag
     1021 cgtgacattt cgcactcatc agctgagcgt atcatcacac ctgacacaac tatcttgatt
     1081 gactacatgc tcaaccgctt tggtaatatc gttaagaact tgactgtctt cccggaaaat
     1141 atgatgcgca atatggaatc aacttttggt ttgatttata gtcaacgtgt tatgctcaaa
     1201 ttgattgaaa aaggaatgac acgagaagaa gcttatgact tagttcaacc taagacagct
     1261 tattcctggg acaatcaagt ggatttcaaa ccacttttag aagaagacac caaagttacc
     1321 tcttgtctta cacaagaaga aattgatgaa ctatttaatc cgatttatta cacaaaacgt
     1381 gttgatgata tttttaagcg tttagggatt taatataaaa aaaagaaggt gattcccttc
     1441 ttttttattt aaaaaaacga atattttctt taaaaatatt aaaaaggtta gtttttaatt
     1501 agacgctgtg atataataaa gaaaacagtt gttggagaga aaccatgtta gaacattttg
     1561 gtggaaaagt aaaagtgtta agacttgaaa agaggattag tcgcgaggac ttgtgtgggg
     1621 atgagtctga actttctgtt cgtcaattag cacggataga actaggtcaa tccataccaa
     1681 gtttaagtaa ggttattttt attgcaaaag ccttaaacgt tagtgtcggt tacttaactg
     1741 atggtgctga tttagaacta cctaagcgtt acaaagaatt aaaatacctt atcttaagga
     1801 caccaactta catggatgat ggaaaattac aagtacgaga agagcagttt gatgaaattt
     1861 ttgaggatta ttatgataaa ttaccagagg aagagaaaat aatcattgat tgtttacagg
     1921 caactttaga tactttattg agtgagaata ctaactttgg cattgactta cttcaagaat
     1981 attttaatca aataaagact aaggtacgct ttaggcaaaa tgatttaata cttctagaat
     2041 tatatttagc ttatcttgat attgagggaa tggatggaca atattcagat aagatttttt
     2101 atga
//
LOCUS       DAUGJR010000082         2057 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUGJR010000082 DAUGJR010000000
VERSION     DAUGJR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2057
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.082"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(22..708)
                     /locus_tag="VH800_001734"
                     /pseudo
     CDS             complement(22..708)
                     /locus_tag="VH800_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1026..1242
                     /locus_tag="VH800_001735"
                     /pseudo
     CDS             1026..1242
                     /locus_tag="VH800_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
     gene            1255..1455
                     /locus_tag="VH800_001736"
     CDS             1255..1455
                     /locus_tag="VH800_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8362777.1"
                     /translation="MTTMKELTINDMSSISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            1749..1943
                     /locus_tag="VH800_001737"
     CDS             1749..1943
                     /locus_tag="VH800_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ8362778.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIP
                     WQGYILCGAAGAATNIIWPH"
BASE COUNT          656 a          307 c          424 g          670 t
ORIGIN      
        1 caagagtaga gtttttgaat attagtcaaa taaactatca agtgtgtcaa agcatgctcc
       61 gaatccttta tgaatacgag ctccgaactt aatattatag tcctcgaaaa tacttacaag
      121 acatcgttct aaggcttctt catttggaaa aaccaccctc cttcttgctt tgtcgcttga
      181 tttctttatt gagtgattca atcaagtttg tagagtaaat actagaccaa atgtaatgtg
      241 gaaattgata gaaagttagg agattttccg ttgtttcaag tgatgtcata acctttttgt
      301 aacgaggctt ccactcagaa acaagtggtc accatacatg cgcttaataa tgtcactgat
      361 ttcgcgtgtc gtaacgccag tctgatagag tttgatcact atctcttcca agtggtcctc
      421 tcgtctagca taagatggta ataaaactgg tgaaaactcg ccgtttcgat ctcttgggat
      481 gattaaattg actaagccat actttgtttc aaactgacga gaataagtcc cattacggct
      541 attacctgtg ttgtaacctt ctttttcata aggttcataa ccaagaaaag ctgatagttc
      601 aacttgcaag aggtcattca tagctatttc taaagaggag cgaaagaatt catcaatatc
      661 ttgtttttgt gctaggaagt taagtaattc tgtggtaaac tgagtcatgg gaataaatct
      721 ctttctagta agtgtcgcaa ctctactata caggatttat tcctttttgt gtgtttacac
      781 aagatatttt acactaccat caaaaatctt aaaaggtatt tataaaagca tgaatggtat
      841 catttaaact tcttaattaa ttaactattg tcacagcgta agtgtagaga ggataaaaag
      901 acatttcatg atgaaaaata gccttttaag attttgaaac catgatactg ttctttatga
      961 tattctgtac tagctcgagg ttgcaacgag acaaatttaa gaattatgaa aagaagttat
     1021 tcgatatgga gataaagaaa ctggaaacat ttcaccaaat gactatagaa aagcttgcca
     1081 aggttgaggg tggtaagaat aattggcagg caaatgtcag tggggttatc gctgcaggta
     1141 gtgctggagc tgctataggt tttccagttt gcggtgtagc ctggagctaa aacagctatt
     1201 actctttggg ctggtgtaac aggagctaca ggcggattct agaggaagga aaggatgaca
     1261 acaatgaagg aattaacaat taatgacatg tctagtataa gtggaggaaa cgctccagga
     1321 gatgctgtaa ttggtggtct tggaggctta gcttctggat tgaaattttg taaactgcca
     1381 catccagtat tgacaggtgg atgtgttgta ggatttacag ttggtggagc atatttggga
     1441 tatacagcaa attaaatgat ctatacgatt tttattatta tgcatgcgtc tataatgttt
     1501 ttaatgattg ttgatgccat tcataaaaaa atgttgataa atctatacca tatttagtgt
     1561 ttttaatttt caatcaatta tccctttcgg aaaaatcggt aaacatgtta tctatcgtag
     1621 ctttggtagc gtcattattt gtttttatcg ataaaagaaa atagtgatta tgccaatgaa
     1681 tttagatatc actcttagct ttttaaaata caaaagagtg aaattaaaat gaaaaagact
     1741 tcaaaaatat ggaagtgcta aaaaatggtc tggctatcat aaatggaggc ggaaaagacg
     1801 gagcaaatat ctttttgaca gggatggcag gtgctgcgca gggagtgaca gtttgtgctc
     1861 agacaggcgt atttatccct tggcaaggtt atattttgtg tggagcagct ggtgctgcta
     1921 caaatattat ctggcctcac taaatatata aatgactatc tatcactgat gtataagtag
     1981 tagaggagtg gtatgaaaac tttagatatt gttgtttgct atacaatagg aatgatttta
     2041 tcattaggtc gtcttat
//
LOCUS       DAUGJR010000083         2043 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUGJR010000083 DAUGJR010000000
VERSION     DAUGJR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2043
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.083"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1663
                     /locus_tag="VH800_001738"
     CDS             <1..1663
                     /locus_tag="VH800_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8362779.1"
                     /translation="RSQELGVLAILGFSKRELTKLLTLENLVILVLSYLVSLLLGPTL
                     YFLAVLAITHLLNLTMEVQWFITVNEIIESLGILVVVFLINVITNGLIISKQSLIEFV
                     NFSRKAEKKIKIRKVRAIIAITALLLSYILCLATVFSSTRNMLLSIGMVPVSLLIIVL
                     VVLGTVFTIRYGLAFVVSLLKENKKRLYRPLSNIIYPKFNYRIATKNKLLTVLGGLLT
                     VTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVESENGQVNVTTILENDQVSLVDVGLL
                     RLNTIPEVTITDSGQTIPYFDIINYSDYKELMKAQGRTNSIEGSKSLPLLINYYPTEI
                     SLGKTFNLGNAYDVTVKQVSTNNVFSFSTSVTTLVVSDKLYAKLSSRFPEKEMTIRTF
                     NGTSIRSSEAFYNQFSMVPDVISSYSKEHTVKTANIATYIFITFLSILFIICTGSILY
                     FTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYETGILFLIPVFIGIVNGGMLLIYYK
                     YLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVLTLRLVTSIIKN"
     gene            1703..>2043
                     /locus_tag="VH800_001739"
     CDS             1703..>2043
                     /locus_tag="VH800_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362780.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEIT"
BASE COUNT          664 a          301 c          352 g          726 t
ORIGIN      
        1 acgtagtcaa gagcttggag tcttagcaat actagggttt tcaaaaagag aattaacaaa
       61 attactaact ttagaaaatc ttgttattct agttctgagt tacttggtaa gtttattgct
      121 gggaccgact ttatattttt tagctgtact ggcaattact catctattga atttaacaat
      181 ggaagttcag tggtttatta cagttaatga gattatagag tctttaggaa tattagtcgt
      241 agtttttctg attaatgtca tcacaaatgg acttatcatt agtaaacagt ctttgattga
      301 atttgttaat ttctcaagaa aggctgagaa aaaaattaag ataagaaaag tcagagctat
      361 tattgctatc actgcattgc tattgtcata tattttatgt ttggcgacag tgttttcatc
      421 cacacgaaat atgctattaa gcatagggat ggtaccggtt tctctattga taattgtctt
      481 agttgtttta ggaacagtgt tcaccatcag atatggattg gcttttgtag tttcgttgtt
      541 aaaagaaaat aaaaaaaggt tataccgtcc tctgtctaat atcatctatc ccaaatttaa
      601 ctatcgtatt gcaacaaaaa ataaattatt aacagtcttg ggaggtcttt taacagtaac
      661 cgtttcagtt gccggaatga tggtaatgct ctatgcttat tctcttaatg ggatagagag
      721 gttgactcca tctgccatag aatataatgt tgaatcagaa aacggtcaag tcaatgttac
      781 aactatttta gagaacgacc aagtgagctt ggttgatgtt ggcctgttgc gattgaatac
      841 tatcccagag gtgactatca cagactctgg gcaaacaata ccttattttg atataattaa
      901 ctacagtgac tacaaagagt taatgaaagc tcaaggcaga acaaattcta ttgaaggtag
      961 taagtcactc ccattgttaa taaattatta tccaacagaa attagccttg gaaaaacctt
     1021 taacttagga aatgcatatg atgttactgt aaaacaagta tcaacgaata atgtttttag
     1081 tttttctaca agtgtcacga ccctggttgt ttctgataaa ttatatgcta aacttagttc
     1141 tcgttttcca gagaaagaaa tgacaattag gacttttaat ggaacttcga ttaggtcaag
     1201 tgaagcattt tacaatcagt ttagtatggt tcctgatgtt atcagtagtt atagtaagga
     1261 acacacagta aagactgcta atattgcgac ttatatcttt ataactttcc tatccatact
     1321 ctttattatt tgtacaggta gtattctgta ctttacaagc ctcatcgaaa tcatggaaaa
     1381 taaagaagaa tatggctatc taagtaagct aggttatagt aaaaaaatga ttcatcggat
     1441 tcttcgatat gaaacaggta tacttttcct tattcctgta ttcattggga ttgtaaatgg
     1501 tggtatgttg cttatttact ataaatattt attcatggat acattggtag caggcaatat
     1561 cataatgtta tctttattgc tttgtctgct tttcttcttg ataatatatg gcacatttta
     1621 tgtattgaca ttgcggttag tgacatccat aatcaaaaat taattttaaa aatcttttaa
     1681 ctttaacgat taagtaaata atatgataag aataaaaaac ataacaaaga gtaagttctt
     1741 tgggactgca ataatcttgt tgcaacaatt aatagccttg ttaattttgg tctataatcg
     1801 agagaacctg tctcttcttt tctctgaaaa agtagctctt gtaatgaccc ttattgatac
     1861 agcttttatt tggctggcaa caatattacg ccaaaaacaa ggtgatattt ttaaaaggat
     1921 tatttctatc atctccttaa caatttggca atacttagta tctgtgctga caagaggaac
     1981 tcctctcttt ttaagcagtg gactacagat tatattgctc tattgttata ccgttgagat
     2041 tac
//
LOCUS       DAUGJR010000084         1988 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.084, whole genome shotgun sequence.
ACCESSION   DAUGJR010000084 DAUGJR010000000
VERSION     DAUGJR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1988
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.084"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..421
                     /locus_tag="VH800_001740"
     CDS             <1..421
                     /locus_tag="VH800_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8362781.1"
                     /translation="IDYHYYLTTTGSCIDFGEEGAVGRGNKTHGIISSFRPNTMEAPA
                     GKNCTYFVGKVWGFLSDTIAKEIYEAFNTPCQIIMQLNIGSKLYRPTHLFIQTEESVD
                     QERVLEIVNRHLNNGKQNTNLILSTQHFIPKTNVYDG"
     gene            405..1373
                     /locus_tag="VH800_001741"
     CDS             405..1373
                     /locus_tag="VH800_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ8362782.1"
                     /translation="MSMMDKTVLYFGLVEISFDVPDFIFQKIKEQNNKIRYYSKSINI
                     LGSVKFINSNQQFIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLIEHSDTLLI
                     HAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSNSGILLTYA
                     GTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGIRTCNFSTE
                     ISKIYYIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNGKYFSTMPL
                     INYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            1428..>1988
                     /locus_tag="VH800_001742"
     CDS             1428..>1988
                     /locus_tag="VH800_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8362783.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKIFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFL"
BASE COUNT          730 a          232 c          359 g          667 t
ORIGIN      
        1 tattgattac cattattatt taactactac aggttcttgt attgattttg gagaagaagg
       61 tgcagttggt cgaggtaata aaactcatgg tatcatatca agttttaggc caaatactat
      121 ggaagcacca gctggaaaaa attgtactta ttttgtagga aaggtttggg gatttttgtc
      181 tgatactatt gccaaagaaa tttatgaagc attcaatact ccctgtcaaa tcattatgca
      241 attaaatatt ggatcaaaat tgtatagacc aacccattta tttattcaga cagaagaaag
      301 tgttgatcaa gaaagagtat tagaaattgt taacaggcat ttaaataatg gtaaacaaaa
      361 tactaattta atcttgtcaa ctcaacattt tattcctaaa accaatgtct atgatggata
      421 aaactgtttt atattttggg ttggttgaaa tttcttttga tgtgcctgac tttatatttc
      481 aaaaaataaa agagcagaat aataaaatta gatattatag caaatcaata aatatattag
      541 gtagtgtaaa atttattaac agcaatcagc aatttataga atatgatggc aatggaaata
      601 ttttagttta tggaagatta aagtatttta aagaaggaat ttcattatac tacattggag
      661 agtacttagc tgaatgtctc ttgattgaac atagtgacac cttattaatt catgcagcag
      721 cagtttataa tcctttatct ggccattcaa ttttactatt aggagataaa ggtgctggaa
      781 aaactacggt tgcaataagg ctttgtatag aacatgggta tcaccttatt ggtaatgacc
      841 aggtaatatt tggttcgaac tctggaatac tactaactta tgcagggaca tctttcttta
      901 aaataagaag gacagctgtt ttgtcggaca atttactgtt taaattattt agcaaatttt
      961 ttaatcgttc attacaattt aataaggcaa gttgggatga taaaatttca attttcccaa
     1021 aggagttggg aatacgaact tgtaattttt ctactgaaat ctcaaaaatt tattatataa
     1081 agacagacaa gaaagaaaag caaatttatc attcaatttg gagtgatagt ttagcaagtc
     1141 tatatctaaa tgagctattg ggaaggcata tttctggaca ggttgcatgt tttcaatcag
     1201 ataatggaaa atatttttct acaatgcctt tgataaatta tgaaaaaaat aatcgggtac
     1261 gagaacagat agtgaagggt attttcgcta aacaaaaatt atttaaaatt acagcagcta
     1321 cgccagctaa gattgcagaa gcgattatag aaaatgttaa gaaaaactca tagtgtgggt
     1381 gaatttgggg attaatatga agtattgaaa aaggagtaag agtaattatg tttgtgatag
     1441 gcattccaac tttaaatgag gcagataata tcagtagatt agttaaacaa attgatgagt
     1501 atgctgtaaa tttagggaaa gaaattatta ttattaattc ggatagtaaa agtacagatg
     1561 gaactccgca gattttttta gaaaccaaaa cttataacac caaagtttcg atagtatcag
     1621 aagctaaagg aaaaggttat aatgtgagaa atattttcga atatgcaata aatcatgtgc
     1681 cgaatttctc cggtttaatt ttgattgatg gagacgttgt ctcaatgaaa aaaatgtggt
     1741 tagaaaagat gtttatagca attgaatctg gaaatgatct tataatccca aattatgcta
     1801 gaaaatcttt tgaaggaaat gcgacaaacc attttattta tcccatgtta gtgaaaattt
     1861 tcaaacgtga tatgccttat caatgcatct ctggtgattt tggattttca agaggattga
     1921 taaaagattt aactttgaaa tgtaattggc acaaatatac attaggttac gggatagata
     1981 ttttttta
//
LOCUS       DAUGJR010000085         1871 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUGJR010000085 DAUGJR010000000
VERSION     DAUGJR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1871
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.085"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            87..728
                     /locus_tag="VH800_001743"
     CDS             87..728
                     /locus_tag="VH800_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEQ8362784.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEVTPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPSDIEKSKGR"
     gene            complement(775..1617)
                     /locus_tag="VH800_001744"
     CDS             complement(775..1617)
                     /locus_tag="VH800_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEQ8362785.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVSVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKADWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAFVLFALGIWLGLWMSQLE
                     EKYK"
BASE COUNT          678 a          326 c          356 g          511 t
ORIGIN      
        1 actaactagg agtaataagt tgaccaaaaa gctaggattg gttatgatga agataagatt
       61 aacggaaaga gaaattaggg aagactatga aggacttatt aaaacagtat caggcaaaac
      121 cactaggaga ggagaagcgg tacgccgtat ttttacctct tattcttgtc aatgatgact
      181 ggcatgtctt atatgaagtc agaagtcagc atatttcaca accgggggaa gtttctttcc
      241 cagggggaca agtagaaaat caggagacac ttcaagaagc tgctatccga gaaacagttg
      301 aggaattgac tgttgatgcg tcccagatcc agctatgggg tgaaattgat tatttagtac
      361 agtcttctag aactattcat tgtttcgttg gtcaattagt cgttgatgac tggaaaagca
      421 tacagcctaa cgaagaagtt gacaaggtct ttatagtacc tttacgtcag ctacttttca
      481 ctgatcctgt ctattatcgt ttagaagtca ctcctattga gacaacggat tttccttttg
      541 accgtattcg taatgggaaa tactaccaat ttagtcaaga gtaccgtagt attccgtttt
      601 atgaaaatct agaagaaacc atatggggaa tgactgccca gtttactaag tgtttaaccg
      661 atattctaaa tgatgaatca attgcaaaga aaaacccctc agatattgaa aaatctaagg
      721 ggagatagag cactagtttg ttggcgtcaa ctttttgtca acaaactgta aaggttattt
      781 gtatttttct tctaattgac tcatccaaag tccgagccaa ataccaagag caaataacac
      841 aaaggccata agccaggtta agatacctgc atgactgtag gaaatggatt cgggactact
      901 actatttgga ataagaatta atagcgtgct ggataataca ataccaatga taaagtggta
      961 aacttttgaa tgatggtgct gtaaagcata atccatactt ttagaaaaag ccaagatggc
     1021 taggactcct ccgatagcaa taggtaagaa agtccctaat aaatccaaag atttgaaccc
     1081 tattaacata ggaccataga gtcctaagat aagtaagaga tttgacgggc ttagtccagg
     1141 gaccagtact cctaaagcaa ttaaggcacc tgctaaaata aaggttaaaa agttagctgg
     1201 taaggtaccg attaagtcat ttaagaagta aagacctagt cctgaaataa caaaggtaag
     1261 gactagccat agccagtcag ctttgtctct ttgagactgc ttggttgact ccttaatcag
     1321 actaggaata gtgccgacaa tagcgccagc aaatccccat aagacgctaa cttgatagtg
     1381 cttaagcaaa aactcaacgg ggaaagaaaa gagagcaata cctaaaatac caccaattcc
     1441 tactggtaag aaaaataaga cattttcaat aaagttatcc ctcatatgag ctaaaaagga
     1501 aatcattcgc tcatagattc ctaaaatggc tgcgagaaca ccaccggata caccaggtaa
     1561 aataaaacct agtgcaataa tcatgccttt aaaaactctt gaaataaatg aaaccattgt
     1621 tgcctcctga aaagaatgat tttattgtat cataaattta aagaattgct gacacaaagc
     1681 tgcatatccc tactaaaata attgttccta ataaataata cattcaattt tgaagatatt
     1741 ttccttaaac accatgtctt tgtgatcaag tcaagtttga ttgtcaaagt tgtaaataaa
     1801 atttacaaag actgtaaacc ttacgataat tattaaaaag ataaacgaaa aaaagcttag
     1861 gtcaaagact t
//
LOCUS       DAUGJR010000086         1752 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUGJR010000086 DAUGJR010000000
VERSION     DAUGJR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1752
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.086"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            281..562
                     /locus_tag="VH800_001745"
     CDS             281..562
                     /locus_tag="VH800_001745"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8362786.1"
                     /translation="MTVLNYVNAGDAKNIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(1008..1095)
                     /locus_tag="VH800_001746"
     tRNA            complement(1008..1095)
                     /locus_tag="VH800_001746"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1059..1061),aa:Ser,seq:gct)
     gene            complement(1105..1178)
                     /locus_tag="VH800_001747"
     tRNA            complement(1105..1178)
                     /locus_tag="VH800_001747"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1142..1144),aa:Ile,seq:gat)
     gene            complement(1213..1283)
                     /locus_tag="VH800_001748"
     tRNA            complement(1213..1283)
                     /locus_tag="VH800_001748"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1249..1251),aa:Gly,seq:tcc)
     gene            complement(1296..1368)
                     /locus_tag="VH800_001749"
     tRNA            complement(1296..1368)
                     /locus_tag="VH800_001749"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1333..1335),aa:Phe,seq:gaa)
     gene            complement(1389..1462)
                     /locus_tag="VH800_001750"
     tRNA            complement(1389..1462)
                     /locus_tag="VH800_001750"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1426..1428),aa:Met,seq:cat)
     gene            complement(1472..1561)
                     /locus_tag="VH800_001751"
     tRNA            complement(1472..1561)
                     /locus_tag="VH800_001751"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1523..1525),aa:Ser,seq:tga)
     gene            complement(1584..1657)
                     /locus_tag="VH800_001752"
     tRNA            complement(1584..1657)
                     /locus_tag="VH800_001752"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1621..1623),aa:Ile,seq:cat)
     gene            complement(1678..1751)
                     /locus_tag="VH800_001753"
     tRNA            complement(1678..1751)
                     /locus_tag="VH800_001753"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1715..1717),aa:Met,seq:cat)
BASE COUNT          569 a          410 c          281 g          492 t
ORIGIN      
        1 gtttttttat aagctaacta tcgaaaactg gtcatctata aatcttagta ttccatcact
       61 caatcacaat tcataaagac tcgcaaactt tcacaacttt taattctata ctttctgtag
      121 taggtaaatc cacctcaaag attatagagt ctttttaaac atatataaaa agttccatat
      181 gacgatctat aatgaaaagc gaccaaacta tcatttcaga aagactcata tagaataatc
      241 cgattatagt ataatttcat taggaatcta aaaccttagc atcacggttt taaattatgt
      301 aaatgctggg gacgcaaaaa acattcataa tcatctcttt cattatacca gacaggttag
      361 aaggcatgtc aaagttatta ccataggcat actcagtgcc cactactatg agattactat
      421 gctttttcta caggctaaaa ttatcctcga ttgttttcat atcccccaac gtcttagaca
      481 agctataact cgctttcgta tccgaatcat aaatacttct gctataaaac ctatcgcgta
      541 tagaactctc aaactttact gaaaactcat acagcatgat tcatggaagc tcatcaataa
      601 tagctttatt gcccaatttt tcgtacgccc ataactaaca tctagaaaag aaaagctctt
      661 actcacaaga tctctgaatt tcaataatta ttcctaactc tatcaactct tgctcttccc
      721 atttttcaga caatttttaa aatttttcta aaagaaaaga acaagattag caatatactt
      781 aaactcaact actctaaggc caaattagaa acagtcaaca accttatcaa agccatgaag
      841 ttaaatgttt tactcctcta cagtagtcaa agagcctatc attttagtta tcgaaataat
      901 gaacaattta aatattctat ttagttggtt ttgaagatta caaaaaaaga cgataaccgt
      961 cttctttccc ctttatttac aattcatcca ttaatatgtt tacaaaacgg agaataaggg
     1021 attcgaaccc ttgcgccagt tacccgacct aacgatttag caaaccgtcc tcttcagcct
     1081 cttgagtaat tctccaaata tatatgggca cgagtggact cgaaccaccg acctcacgct
     1141 tatcaggcgt gcgctctaac cacctgagct acgcgcccaa gcttttattg atatagcttg
     1201 ggaaaactat aaagcgggtg acgagaatcg aactcgcgac aacagcttgg aaggctgtag
     1261 ttttaccact aaactacacc cgcaatatga taacatggcg cgagacggaa tcgaaccgcc
     1321 gacacatgga gcttcaatcc attgctctac caactgagct accgagccaa caactacata
     1381 cttatgtatt gcgggagcag gatttgaacc tacgaccttc gggttatgag cccgacgagc
     1441 tacctaactg ctccatcccg cgatagttaa aaggaggatg tgggattcga acccacgcac
     1501 gcttttacac gcctgacggt tttcaagacc gttcccttca gccggacttg ggtaatcctc
     1561 caaaataatg attatctatg atatggacct tgtaggactc gaacctacga ccgctcggtt
     1621 atgagccgag tgctctaacc agttgagcta aaggtcccaa gtcatccata aaaataatag
     1681 cggcgaaggg gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga
     1741 gctacaccgc ca
//
LOCUS       DAUGJR010000087         1587 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUGJR010000087 DAUGJR010000000
VERSION     DAUGJR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1587
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.087"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(274..1395)
                     /gene="mnmA"
                     /locus_tag="VH800_001754"
     CDS             complement(274..1395)
                     /gene="mnmA"
                     /locus_tag="VH800_001754"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEQ8362787.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADKIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          504 a          334 c          255 g          494 t
ORIGIN      
        1 atgaaataat ctgttttacg aaatacctaa tcatcaaaat atctgttgta atactagaga
       61 aagtgagtct catgatcgta tgatttctac agtaactaat aaagtaatga ctcaactttt
      121 acgaactatt tttaaaaata atgtgattat atttaaaata tacagatatc ataaattaat
      181 ccattaacgc atgattggct tttataaata atatcatatg atgtcaaagg aattgttgaa
      241 tgtccctttc tttttatctt aataaaagat tcattaaatg tactgacaag gctgcccatt
      301 tttataagcc atgtcaatca taccaccacc aaggcattct tttccgtcat agaaaacaac
      361 agcttgacca ggagtaatcg cgcgctgtgg ctctgcaaaa acaacttctg ccttatctcc
      421 tcgaacatgc accgccacgt gtgaatcggg ttgacgatag cgaaatttag cagtacattc
      481 aaatgtgaac tcttctggca tctcacgtgt aaaatggatg actgaggcgt caagactatt
      541 tgacattagg gcttcatggt agaaaccttg accaacgtat aaaatatttt gcgacaaatc
      601 tttaccgaca acaaaccaag gttgattatc cccaccatgc tgaccaccaa tgcccagacc
      661 cccacgctga ccaatagtat aatacataag gccggcatgt tctcccatat cgcgaccatc
      721 aatagtcatc atgcgacctt tttgtgccgg taagtactgg ctcaaaaact gtttgaaatt
      781 cttttcacca ataaaacaaa tacctgttga atctttcttt ttagccgttg caagccctgc
      841 tcgctcagcg atttctctaa cttctgactt ttgcaaatga ccaaggggga ataaagtctt
      901 ttgtagttgt tcctgtgata gttgacttaa aaagtaggtt tggtctttgc cattatcagc
      961 tccacgtaac atgtgaaccg taccattttc atcacgcttg acttgagcat agtgtcccgt
     1021 tgctacataa tctgcaccta aagtcatggc atagtcaagg aaagctttaa attttatttc
     1081 cttattacac atgacatcag gatttggagt acgacctgct cggtattcgg ccaagaaata
     1141 ttcaaatact ctgtcccaat attctttttc aaaattgact gaatagtaag gaataccgat
     1201 tttatcagca acggctgcta catctttgta atcttcagta gctgtgcaaa caccaaattc
     1261 atctgtatcg tcccagtttt tcatgaagac accaataaca tcataacctt gctcctttaa
     1321 aagtagagct gttacagatg aatcaacgcc accactcata ccaacgacaa cacgtatctt
     1381 tgagttatct gtcataaaaa attctcccat caataataag atagaaaaag ataatcatca
     1441 tattatgaat attatgattc tttttcttat cagttaacgt acgattgaag gtcgtcgttt
     1501 tcaaaagtcg atttgaaggt cgattttgaa gcgccatcag cgcaaacctt attataacaa
     1561 ttactgcgtg gaatgccaat catttta
//
LOCUS       DAUGJR010000088         1575 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUGJR010000088 DAUGJR010000000
VERSION     DAUGJR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1575
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.088"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..562
                     /locus_tag="VH800_001755"
     CDS             <1..562
                     /locus_tag="VH800_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8362788.1"
                     /translation="SQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            741..1436
                     /locus_tag="VH800_001756"
     CDS             741..1436
                     /locus_tag="VH800_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8362789.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            1438..>1575
                     /locus_tag="VH800_001757"
     CDS             1438..>1575
                     /locus_tag="VH800_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 family protein"
                     /protein_id="HEQ8362790.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LL"
BASE COUNT          532 a          229 c          286 g          528 t
ORIGIN      
        1 aagccaattt ttctcagtta ttacaatgca aaatcatatt ccttggtcat ccgattatcc
       61 tgaagaaatt gttgctgaag gaaaaaattt cacggaagaa gaaaatcaca acctaacaag
      121 ttatgctcgg ttattatcgt ttactgataa ggaaacaaga gcatttttag aaaaattaac
      181 acaaattaac aagcctatca cagtggtgtt ttacggagat catttacccg gtttatatcc
      241 tgatagtgct tttaacaagc atattgaaaa taaatacctt actgattatt ttatttggag
      301 taatggtact aacgagaaaa aaaatcatcc gcttatcaac tcaagtgatt ttactgcagc
      361 tttatttgag catactgatt caaaagtatc accttactat gctttgttaa cagaggtact
      421 gaataaagct agtgtcgata aatcaccaga tagtcctgaa gttaaagcta ttcagaatga
      481 tttaaaaaat atccaatacg atgtgactat aggaaaaggt taccttttga aacacaaaac
      541 tttttttaag atatcacgtt aagaaaaatg ctaggctgtc cgagtatagg caagcatcaa
      601 ggtttggtaa tttgctcaaa tgattgtcaa cagagtgtct aggaccaggt ttaaaagatt
      661 ataattctta aggtcttatt cgtttataaa aaatgaatac tcttttaaaa tcttaattga
      721 aatgaatagg agaagttttc gtgaaaaagt taatcattat tcctgcttac aatgaaagca
      781 gtaatattgt caatactata cgtactattg aatcagatgc cccggatttt gactatatca
      841 ttattgatga ttgctcaacg gataatacgt tagcaatatg tcaaaaacag gggttcaatg
      901 ttatttcttt gcccattaac ctgggaattg gcggtgcggt gcaaactggc tatcgttatg
      961 cacaaagatg tggatatgac gttgcagttc aagtagatgg agatggtcag cacaatccat
     1021 gctatttgga aaaaatggtt gaggtattag ttcaatcttc agtaaatatg gtaattggat
     1081 cacgatttat cacaaaagaa gggtttcagt catcatttgc tcgacgtatc ggcataaagt
     1141 attttacttg gcttattgcg ctactaacag gaaaaaaaat aacagatgca acgtcaggtc
     1201 taaggttaat tgaccgttca ttgattgaac gttttgctaa tcattatcca gatgattatc
     1261 ctgaacctga aacagttgtt gatgtattgg ttagtcattt taaagtgaaa gaaattcctg
     1321 ttgtaatgaa tgagcgacaa ggcggtgtgt catctatctc gttgacgaaa tcggtctatt
     1381 atatgattaa agtgacttta gctattttag ttgttagatt gaaaggaaat cgttaaaatg
     1441 acggtaacag ccagtttatt tataagtttt attgtattaa cctttgtttt ctttttgatt
     1501 aacttaatca aaaaagataa actagcgatt aagtactctt tattgtggtt tattttagct
     1561 ttattaattt tacta
//
LOCUS       DAUGJR010000089         1423 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUGJR010000089 DAUGJR010000000
VERSION     DAUGJR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.089"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            95..1165
                     /gene="xerS"
                     /locus_tag="VH800_001758"
     CDS             95..1165
                     /gene="xerS"
                     /locus_tag="VH800_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEQ8362791.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT          455 a          234 c          273 g          461 t
ORIGIN      
        1 tgctcttgta gagaatgaat gtcataaaat acatgagaca atttacgaaa attcattttt
       61 gaaaaaattg ttattgttaa ggaattatga tgatatgaga cgcgaattat tactagaaaa
      121 aattgaaacc tacaaggcta tcatgccctg gtatgtttta gattattacc aatccaaatt
      181 agctgttcca tacagcttta ccaccttata tgagtattta aaagaataca aacgcttttt
      241 tgattggctg atggatgctg atttaacgca ggcgccaaag attgctgata ttgacttgag
      301 cacgcttgag caccttacca agaaggattt agaggccttt gtgctttatt tgcgggaacg
      361 accttctctc aacacctatt ccaccaaaga ggggctttct caaaccacta ttaatcggac
      421 cttgtctgcc ttatcaagcc tttacaagta cttgactgaa gaggttgaaa atgaccaagg
      481 ggagccttat ttttatcgga atgttatgaa aaaagtgtca acaaaaaaga aaaaagaaac
      541 cctggcttcc agagcggaaa atattaagca gaaactgttt ttaggtgatg aaactctagc
      601 tttcttggat tatgtggata aggaatatga gcaaaaattg tctaatcgtg ccaaatcttc
      661 tttccgtaaa aataaggaga gggatttggc tattattgct ctactacttg cttctggtgt
      721 tcgtttgtct gaagcagtga atcttgattt aaaagatgtc aatctaaata tgatgattat
      781 cgaagttatt cgcaaaggcg gaaaacgtga ttcagtcaat gtagcaggtt ttgcgaaagg
      841 ttatttggag tcttatttag ctgttcgtca gagacgttac aaggctgaaa aacaggatct
      901 tgctttcttt ttaacagaat accgtggcgt tccaaatcga atggatgctt ctagtataga
      961 aaagatggtt ggcaagtact ctgaggattt taaaattcgt gtgactcctc acaaattgcg
     1021 tcatacgcta gcgacaagac tatatgatgc tactaaatct caggtgttag ttagtcatca
     1081 attaggccat tcctctactc aagtcacgga tctttatacc catattgtca atgatgagca
     1141 aaaaaatgct ttagataacc tttaatgtta cataattgtt tttatgtaac attaaagata
     1201 aaaatagctt caaaattaac tttaatagat ggctactatt aaccgtgaca gtttggtgtc
     1261 aggccgtttt ccaaactact caagccactt agaaaaagga atattactgc taactttgtc
     1321 ccttctttga atgacttttt tgtgatgttt atagattaaa tctagtaggg ttctcatcaa
     1381 aaagatgaga taagcctgtt tttagtatgt cagtactttt att
//
LOCUS       DAUGJR010000090         1315 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUGJR010000090 DAUGJR010000000
VERSION     DAUGJR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1315
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.090"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..538)
                     /locus_tag="VH800_001759"
     CDS             complement(<1..538)
                     /locus_tag="VH800_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEQ8362792.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIALFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLIT"
     gene            630..977
                     /gene="ssrA"
                     /locus_tag="VH800_001760"
     tmRNA           630..977
                     /gene="ssrA"
                     /locus_tag="VH800_001760"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1129..>1315)
                     /locus_tag="VH800_001761"
     CDS             complement(1129..>1315)
                     /locus_tag="VH800_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8362793.1"
                     /translation="LYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEV
                     VTVERVEEVMVELDYIK"
BASE COUNT          435 a          256 c          201 g          423 t
ORIGIN      
        1 tagttattaa aagaatagtt acaaagcgct ttaaagacat gtccgtcaat cccgtaatca
       61 taaccataat atcagctgga gaaacaggcg atgccataca aaaaataaat aatttttcat
      121 atcctggtgt ctccaaacgc ctttcatact tgtaaaatgt tttgtcattt acaaagagta
      181 agataaattt acgaccataa gtcttaacga gcaagaagag ggctatactg ccaataatga
      241 tgcctacata attataaata aaacctgtta cagggccaaa gattaaaaaa cctgcaactg
      301 tcgtaaggcc tccaggaatc acaggaaaaa caatctgtat gatctgcacg acaataaaaa
      361 caaacggccc ccataatcta tagcgctgca ctaagtcttt aagagcatta ctatcgttta
      421 atatacctag tctatacagc caaaaagcga ggaaaaaagt accaattagt gcaataattc
      481 ctaaaatttt gataattttt tgccataata tataggcttt tgaattacgt tttgtcatag
      541 actaatcata ccataagctg taaaattttg ctatttaaaa aaagttttga tagaatagtt
      601 agtgtaagaa attggttaat tatctatttg gggttgttac ggattcgaca ggcattatga
      661 ggcatgtttt gcgtcccatc ggcagatgta aattgccagt taaatataac tgcaaaaaat
      721 acaaactctt acgctttagc tgcctaaaaa ccagctagcg tgacttctac aagattgctt
      781 gtgtcctgtt agaagtctca aaatagcaag ctacggttac gaaattgtct agtttcgtga
      841 caagagattg atagactcgc aaactaatgg cttgagttat gtgtctttag tttgttaaat
      901 gaagacataa cctatggacg tagacaaata tgttggcagg tgtttggacg tgggttcgac
      961 tcccaccagc tccatcaatg cttaccgtaa gtaatcataa cttactaaaa ccttgttaca
     1021 tcaaggtttt ttctttttgt cttgttcatg agttaccata actttctata ttattgacaa
     1081 ctaaattgac aactcttcaa ttatttttct gtctactcaa agttttcttc atttgatata
     1141 gtctaattcc accatcactt cttccactct ctctaccgtc acaacttcat catctctcac
     1201 tttttcgtgt ggtaacacat aatcaaatat ctttccgttt ttacgcacta tcgctactgt
     1261 gtcacctaaa atatacccct tatcaatcgc ttctttaaac tcatctatat ataac
//
LOCUS       DAUGJR010000091         1206 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUGJR010000091 DAUGJR010000000
VERSION     DAUGJR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1206
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.091"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            118..>1206
                     /locus_tag="VH800_001762"
     CDS             118..>1206
                     /locus_tag="VH800_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8362794.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNK"
BASE COUNT          436 a          187 c          190 g          393 t
ORIGIN      
        1 aactatattt tactaacact agaatcccga caattaagtc aaaaaaagtt atcactcacc
       61 taacctgaat aaaaatggta taatcgtaag gatcacacta tttattaagg aaacattatg
      121 aaaattgttc agggagtaca acttcatctg attaagacca aacagtttaa aaccaatcat
      181 attacctttc gtttttcagg tgatttgaac caaaaaacag tagcaaaaag agtcttagtg
      241 gcacagatgt tagcaacagc taatgagtgt tatccaactg ttaggcagtt tagagaaaaa
      301 ttagcacgac tttatggagc tagcttgtca actaacgtgt taacaaaagg gttagttcat
      361 attgtggata tcgatattac ttttattcaa gatagatatg cttgcaatgg ggaaaaaata
      421 ctagatgaaa tgattcagtt tttaaaagat atcttgttct cacccctatt atccatcgcc
      481 cagtatcagc ctaaagtttt tgagactgaa aaaaataatt tgattaacta catcgagtca
      541 gatagagagg attcttttta ctacagctct cttaaggtaa aagaattgtt ttattgtaat
      601 aagaatctac aaatgtcaga atatggtagc ccagaactaa ttgcaaaaga gactgcctat
      661 actagctatc aagaatttca taaaatgctc aatgaagatc agattgatat tttcatttta
      721 ggagattttg atgattatcg cgttgttcag ctaattcatc aatttccact tgataaccga
      781 aataaaaacc taaatttctt tcatttacaa aattctgtca atattattaa agaatctatt
      841 gaaaaaagag cagttcatca atctatttta caattagctt atcacttccc ttcagttttt
      901 ggacaacgtg actattatgc tttagttctt ttaaatgggt tgttaggctc ttttgcacat
      961 tcccgtctct ttataaaaat tagagaagaa gaaggacttg cttatagtat agggtgtcgt
     1021 tttgatagtt atacaggatt atttgaaatt tatactggaa ttgacagtca acatcgcact
     1081 aaaacgttac aactaatcat ccaagaatta aatgccatta aaatgggacg attctcagaa
     1141 caattgatta aaaagaccag atcgatgttg ttgaataatg ccttattatc agaagattat
     1201 aataaa
//
LOCUS       DAUGJR010000092         1128 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUGJR010000092 DAUGJR010000000
VERSION     DAUGJR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.092"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..1093)
                     /locus_tag="VH800_001763"
     CDS             complement(<1..1093)
                     /locus_tag="VH800_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8362795.1"
                     /translation="MFDFANNTFLAGLNPASLSLVAVYQSLESVIGVLFNLFGGVIAD
                     SFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNVILAFMSAFSSPSYKAFTK
                     EIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGVLLLDGLSFLIAALLIS
                     FILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHKSIFIITVLSALVNFFLAAYNLLL
                     PYSNQMFGEISTGLYGTFLTAEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLML
                     APPFYIMFHNAIILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGIIFTITIL
                     FMPIGTGFFSVALNPNNSFNLFIIGSCITT"
BASE COUNT          450 a          187 c          164 g          327 t
ORIGIN      
        1 atgtagtaat gcacgaacca ataataaaaa gattaaagct attgttagga tttaatgcca
       61 ccgagaaaaa gccagtccca ataggcataa aaagaatagt tattgtaaag ataataccaa
      121 acactctccc taaaaaatcg ttatcaacat ctttctggac aagagaaaaa aattgaatat
      181 taaagatgga aagaaataaa ctgaataaag ctggtgacaa agctaaaata attgcattat
      241 gaaacataat ataaaatggg ggagctaaca ttaacatcag tcctgataaa gatagaaaca
      301 atatcaatct catacttgat aattctttat tcacaaaacc acttaatatt gccccaataa
      361 atccaccaat tgcttctgct gttaaaaaag tgccataaag tccagttgaa atttctccaa
      421 acatttgatt actatagggc aacaataaat tataagcggc tagaaaaaaa ttaacaagtg
      481 cagaaagaac ggtaataata aagatggact tatggctgta aacatattta aatcctattt
      541 ttaaatcgtt aaatatttct ctgattgtca ccttctcctt tatcaccact tcgtcattaa
      601 caggtaaaat aaaggaaatt agtaaagcag ctattagaaa tgatagtcca tccaatagta
      661 atacaccgtg tataccaagt agcttatata agaaaattgc taccatagga actgttactt
      721 tgattacagt acttgttgtc tctagcaatg aattaagttg tgatatacta tcttttttaa
      781 caatttcttt tgtaaatgct ttataggatg gactagaaaa agcactcata aatgccaaga
      841 taacattagt tagtacaatg gcataaacca accattgctc ttttgttagg aacgagagta
      901 ctaagcaagc tgtgccacat aagatatttg tagtaataat aatttttttc cgcttgaaac
      961 tgtctgcaat gactccacca aataaattaa atagaacacc tatgacactt tctagagact
     1021 gatatactgc aactaatgat agagacgctg gattaagccc agcaagaaaa gtattgttag
     1081 caaaatcaaa cataacatcg ccaattcgat atataacttt actataca
//
LOCUS       DAUGJR010000093         1056 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUGJR010000093 DAUGJR010000000
VERSION     DAUGJR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.093"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..>1056
                     /locus_tag="VH800_001764"
     CDS             <1..>1056
                     /locus_tag="VH800_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AIPR family protein"
                     /protein_id="HEQ8362796.1"
                     /translation="NQNISSNSQEVIDDFLQGVNSDGSDDVVTYRHIKLNDVYDHMAN
                     QGVAPKIDFEDVVVHNWGRPTLYNDSYKVYYGWLSATDIVNWKEQYGDRIFEKNIRNF
                     KQNTDVNNGIKIISEKVEKNLKGVSTTDYINLKLIGASIINGAQTTGSLFEAYHSEDI
                     DLTNVSVQVQIIVLGEDIDNIGPKITKLSNTQNRIENKDFAAQDKEQERLMKDLAIDG
                     KQYVYRQGVELPNSDEGCDLDSATVALGCYLDDVAISTQMKRAYGSIFDNTNKPPYKL
                     IFNSGTSAYKLWNCVEVYRELQNIEGEYQQDPNNQSKKLMSIHGNRFILHLIFQKLKN
                     NPSLDFENGYITTFPNL"
BASE COUNT          401 a          131 c          197 g          327 t
ORIGIN      
        1 ctaatcaaaa tatatcttca aatagtcaag aagtaataga tgattttttg cagggtgtaa
       61 attctgatgg tagtgatgat gtagtaacat acagacatat aaaacttaat gatgtttatg
      121 atcatatggc taatcaagga gtggctccta aaatagattt cgaggacgtt gtcgttcata
      181 attggggcag acctacatta tacaatgaca gttataaagt ctattatgga tggttatctg
      241 ctactgatat agttaactgg aaagagcaat atggagatcg aatatttgaa aagaatattc
      301 ggaactttaa gcaaaatacg gatgttaata acggaataaa aataatttct gaaaaagttg
      361 aaaaaaatct aaaaggtgtt tcaacaacgg attatatcaa tttaaaattg attggagcaa
      421 gtataattaa tggagcgcaa acaacgggtt ctttatttga agcataccat tctgaagata
      481 ttgatttgac aaatgtttca gtccaagttc aaataatagt attaggagaa gatattgata
      541 atatcggacc taaaataact aagttatcga atactcaaaa tagaatagaa aataaagatt
      601 ttgctgctca ggataaagaa caagaaagat tgatgaaaga tcttgcaatt gatggtaaac
      661 agtatgtgta tcgtcaaggt gtcgagctac ctaattctga tgaaggttgt gatctggata
      721 gtgcaacagt ggctctaggt tgctatttag atgatgttgc aatttctaca cagatgaaga
      781 gagcatatgg tagcattttt gacaatacta ataaacctcc atataagcta atctttaatt
      841 ccggaacttc tgcatataaa ttatggaatt gcgttgaagt gtatcgcgaa ttacaaaaca
      901 tagaagggga gtatcaacaa gatccaaata atcaatctaa aaagttgatg tctattcatg
      961 gaaatagatt tattcttcat ttgattttcc aaaagttaaa aaataaccca agtttagatt
     1021 tcgagaatgg atatattaca acttttccaa atttaa
//
LOCUS       DAUGJR010000094         1022 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUGJR010000094 DAUGJR010000000
VERSION     DAUGJR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1022
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.094"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            31..717
                     /locus_tag="VH800_001765"
     CDS             31..717
                     /locus_tag="VH800_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8362797.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
     gene            710..>1022
                     /locus_tag="VH800_001766"
     CDS             710..>1022
                     /locus_tag="VH800_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8362798.1"
                     /translation="MFKKYSIKNRVWRAVVEIVFGVCITVLMIAIISLSFSKLNIVTS
                     HNVGEEFYIKDKQSIKQLNNYMKTLGLDYVVFDRKTDKAMEGKYLSKEFSLFNEVAEE
                     KN"
BASE COUNT          373 a          110 c          195 g          344 t
ORIGIN      
        1 taagtatttc attatttaaa aggggtaata atgtataaga ttttagccat agatgatgat
       61 aaagaaattc tgaagcttat gaagactgct ttggagattg aaaattatca tgttataacc
      121 tgtcaagaga tagaattacc aatagttttt gatgatttta aaggatatga tttgatctta
      181 ttggatatca tgatgcctaa tataagtgga actgagtttt gttataaaat tcgggaagaa
      241 gttcattctc caattatttt tgttagcgct ttagatggcg ataatgaaat tgtccaagct
      301 ttaaatatag ggggagacga ttttattgtg aaaccattta gcttaaaaca attcgtagct
      361 aaagttaact ctcatttgaa gagagaagag agagcaaaga taaagaatga ggctgaggag
      421 agagtgaagc gtagttttcc acctatagaa atctatctag aggaacgtat gttatatatt
      481 gataaacagc cgttattcct gacttataga gagtacgaaa ttttagaatt actgtcacgt
      541 catccgtata aagttttcac aaaagaagag atatatgaac aagtatatag cgatgaagct
      601 tcagcattgt ttcattctat ttcagaatat atctatcaga ttagaatgaa attttcaagt
      661 tttggaatta atccaataaa aactattcgc gggattggtt ataaatggga tgtttaaaaa
      721 atattcaata aaaaatcgtg tttggcgcgc cgtcgttgaa attgtctttg gagtttgtat
      781 cactgtttta atgattgcga taatatcgct ttctttttca aagttaaata tagtgacatc
      841 tcataatgtg ggagaagaat tttatattaa agataaacag tcaatcaaac agttgaacaa
      901 ttatatgaag acattgggat tagattatgt tgtttttgat agaaaaacag ataaagctat
      961 ggaaggaaaa tatttatcta aagaattttc tttatttaac gaagttgcag aagaaaaaaa
     1021 ta
//
LOCUS       DAUGJR010000095          982 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUGJR010000095 DAUGJR010000000
VERSION     DAUGJR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..982
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.095"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..>982
                     /locus_tag="VH800_001767"
     CDS             <1..>982
                     /locus_tag="VH800_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8362799.1"
                     /translation="LNLPLKFISLLFVVSTLLIVFLPKKLEVATIIFILVFGTISAII
                     SPINDIPDEYVHYSRTVYISEGDINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKAT
                     KHSTREYSYPYIKGTNAYYSFSYIPQALGILVGNALDLPILLTYYFGRLCNLISYAML
                     AFIAIKLSGSFKQVIAVVTLLPMNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKS
                     NYNTKFFLYLVLCGLLVLSKFTYFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFL
                     FAAMWFRLYGQVKTPYVADFLKEVNVSQQVKNMLESPIVYSSIIIRHMVI"
BASE COUNT          323 a          151 c          145 g          363 t
ORIGIN      
        1 gtttaaatct acctttaaaa tttattagtc ttctttttgt ggtgagcact ttactgatag
       61 tgtttttacc aaaaaagtta gaggttgcta cgatcatttt tattttagta tttggaacga
      121 tatctgctat catatcacct ataaatgata ttcctgatga atatgttcat tattcaagga
      181 cagtttatat ctcagaaggt gatattaatc ttaccaacaa taacaaaaag ttaagaatat
      241 ccaaagatgt tgataagctt attaaacagt caggaaaaac atttataaca tcaaacttga
      301 aagcaactaa acacagcaca agagagtata gctatcctta catcaaagga actaatgcat
      361 attatagttt ttcttatata ccacaagctt tgggtatttt agtaggaaat gcgctggatt
      421 tacctatact tttaacatat tatttcggaa gattgtgcaa ccttattagc tacgctatgc
      481 ttgcttttat agctatcaag ttgtctggtt cttttaaaca agtgatagct gttgttactt
      541 tactacctat gaacatttat ttagcagcat cttttaatca agacggcttt gctatcggtt
      601 tagttttagt aacaattgga ttgtttatta acttgctctc atcaaaagat aaatctaact
      661 ataataccaa attcttcctt tatttagttc tatgtgggtt actagttctt tcaaaattca
      721 catacttttt attagtatgc cttccattat ttattcctaa tgaaaaattc ggaaaaaata
      781 ccaagttagt catcttgaaa aaattgggag gactattact catttttctt tttgctgcaa
      841 tgtggtttag actttatgga caggttaaaa ccccatatgt cgcggatttt ctaaaagaag
      901 taaacgttag ccagcaagtt aaaaatatgc tagaatcccc tatagtctat agcagtatta
      961 ttattagaca tatggtaatt aa
//
LOCUS       DAUGJR010000096          939 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUGJR010000096 DAUGJR010000000
VERSION     DAUGJR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.096"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..>939
                     /locus_tag="VH800_001768"
     CDS             <1..>939
                     /locus_tag="VH800_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEQ8362800.1"
                     /translation="GLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAINKLLC
                     KAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNILKINKKATIVIK
                     STVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNESRNSQLFLDIL
                     TDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIEAM
                     GYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKM
                     ILNSSAKTIGIYRINSKKDSDNCRESSTIDVAKLLKS"
BASE COUNT          348 a          142 c          148 g          301 t
ORIGIN      
        1 ggattatcga tagggctcct acttgcaaag gaacacgacg tcaccttttt tgatattgat
       61 aataaaaaaa ttgatttaat aaataaaagg caatcccctc ttaaagaagc agctataaac
      121 aaacttttat gtaaggcaaa aaatattaat gcaacttctt ctgaagaatt agcatataag
      181 gatgcgactt tcataatctt gtctttgcca accaacctaa aatttaataa gcttgatact
      241 tccattatcg aaatttctgt aagtaatatt ttaaagataa acaaaaaggc tacaattgta
      301 ataaagtcga cagttccaat tggttttaca gaatatttaa ggaatcgatt tcactacaac
      361 gatatcattt tttcacctga gttccttagg gaaggatcaa ctattcatga tcaattgtat
      421 ccttcgagaa ctatagttgg aaatgaatct agaaattctc aattattctt agacatacta
      481 acagatatat cggttgaaaa agactcgcca tctttattag ttggctcttc tgaagcagaa
      541 gcgataaagt tattttcgaa tgcatacttg gcacaaaaaa ttgctttttt taatgagttg
      601 gatacgtttg ctgaaatgca aaatttggac tcaaaaaaaa ttattgaggc tatgggatat
      661 gaccagagaa taggaaattc gcacaataat ccttctttcg gttttggtgg gtactgtctt
      721 cctaaggata ttaagcaatt agagtatcat tttaaagaaa ttccagcacc aattattacc
      781 agtataagtg aatctaattt attaagaaaa attcatatag caaaaatgat tttgaacagc
      841 tcagctaaaa caataggaat ttatagaatt aattccaaaa aagattcgga taattgtagg
      901 gaatcttcta caattgatgt tgctaaactt ctaaaaagc
//
LOCUS       DAUGJR010000097          882 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUGJR010000097 DAUGJR010000000
VERSION     DAUGJR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.097"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(211..306)
                     /locus_tag="VH800_001769"
     CDS             complement(211..306)
                     /locus_tag="VH800_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEQ8362801.1"
                     /translation="MCEAIFTTIIAPLLVGIILLLIQKWLDDSAD"
BASE COUNT          285 a          173 c          153 g          271 t
ORIGIN      
        1 gcctctattt taaagtatac tctaaaaaat gtcaatgaaa aatttaaatt tttactaact
       61 ttattactta caagttcttt gacaattgaa tatcgtatgt gatatgatat aggggaagtg
      121 aagatagttt cgtcgcgcat aggcgaacat aaaaacccct tgcaaaatcc tacaaatgca
      181 aggggttttt tctattttgc aatagaagca ctaatcagca ctgtcatcaa gccatttctg
      241 gattaataac aggattattc caaccaatag cggtgcgata atagttgtga agatagcttc
      301 gcacatagac gtcacctcct tagctaaggc aggtatagta gtgccagtca atattatatc
      361 atgtacgtta tcgattggat agcgtacttt tttgtttaaa agtataaaac accacctagc
      421 tgctatctag atggtgctac ggaaattatt ctgctcgaaa tgaaaatgct agagtgtccg
      481 atactctagc acccaccaat tttgattagc tctctgccca tcggacagac aaaacaaatc
      541 ttcgctggat tgggaaccag cactgcatgg tttataggta gcaacaacga ctctataccc
      601 ctaagtcgaa taacggcaat atttttacgt gtcatgccac cactccatct atctctaatt
      661 taaagtgata gacattttcg acttagattc attcctagtt ttgcgcgtct agtccgcttc
      721 ggctccgagt agagcaatgt gtctatttac ctatgagagc acagtacctt tcaaaaattc
      781 tgctaacaat aacatcagct cctttctgta ataaaggtac tttcattata agattgtaag
      841 tcaaaaaaat caagatggtt acaaaaatta ttgagcagaa ta
//
LOCUS       DAUGJR010000098          782 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUGJR010000098 DAUGJR010000000
VERSION     DAUGJR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.098"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(63..136)
                     /locus_tag="VH800_001770"
     tRNA            complement(63..136)
                     /locus_tag="VH800_001770"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(100..102),aa:Arg,seq:acg)
     gene            complement(153..237)
                     /locus_tag="VH800_001771"
     tRNA            complement(153..237)
                     /locus_tag="VH800_001771"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(201..203),aa:Leu,seq:taa)
     gene            complement(246..317)
                     /locus_tag="VH800_001772"
     tRNA            complement(246..317)
                     /locus_tag="VH800_001772"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(283..285),aa:Gly,seq:gcc)
     gene            complement(330..402)
                     /locus_tag="VH800_001773"
     tRNA            complement(330..402)
                     /locus_tag="VH800_001773"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(367..369),aa:Thr,seq:tgt)
     gene            complement(413..494)
                     /locus_tag="VH800_001774"
     tRNA            complement(413..494)
                     /locus_tag="VH800_001774"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(458..460),aa:Leu,seq:tag)
     gene            complement(500..572)
                     /locus_tag="VH800_001775"
     tRNA            complement(500..572)
                     /locus_tag="VH800_001775"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(537..539),aa:Lys,seq:ttt)
     gene            complement(604..676)
                     /locus_tag="VH800_001776"
     tRNA            complement(604..676)
                     /locus_tag="VH800_001776"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(641..643),aa:Asp,seq:gtc)
     gene            complement(694..766)
                     /locus_tag="VH800_001777"
     tRNA            complement(694..766)
                     /locus_tag="VH800_001777"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          203 a          229 c          168 g          182 t
ORIGIN      
        1 aacctgcgac accttggtcc caaaccaagt actctaccaa gctgagctac ttcccgaact
       61 gatgcaccct agaggagtcg aacctctaac cgcctgattc gtagtcaggt actctatcca
      121 gttgagctaa gggtgctatt tcaaaaaatt aatgccgagg accggaatcg aaccggtacg
      181 atgtaaacca tcgcaggatt ttaagtcctg tgcgtctgcc agttccgcca ccccggctcc
      241 tcaaaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt gatgttctac
      301 cactgaacta cgttcgcaac taatctcaat gccggctaca tgacttgaac acgcgaccct
      361 ctgattacaa atcagatgct ctaccaactg agctaagccg gctaatcttt tatgcgggtt
      421 aagggacttg aacccccacg ccgttaagcg ccagatccta aatctggtgc gtctgccaat
      481 tccgccaaac ccgcttttat gacccgtact gggctcgaac cagtgaccca ttgattaaaa
      541 gtcaattgct ctaccaactg agctaacgag tctttccttc aaaaaatatg actactcttt
      601 gaacggtccc gacgggaatc gaacccgcga tcttcgccgt gacagggcga cgtgataacc
      661 gctacactac gggacctgta ttttccaata ctatgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcccattg agtgtgtcat
      781 ta
//
LOCUS       DAUGJR010000099          701 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUGJR010000099 DAUGJR010000000
VERSION     DAUGJR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.099"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..532)
                     /locus_tag="VH800_001778"
     CDS             complement(<1..532)
                     /locus_tag="VH800_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEQ8362802.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVS"
     gene            complement(525..>701)
                     /locus_tag="VH800_001779"
     CDS             complement(525..>701)
                     /locus_tag="VH800_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEQ8362803.1"
                     /translation="KMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRL
                     TQEVALMKKEKTND"
BASE COUNT          256 a          112 c          110 g          223 t
ORIGIN      
        1 atgaaactat acagacagct actaatgcta aagtaagatt tttggaatat aatattattg
       61 ctgtgtacac cataaaaata agagtatttc tgtaggctag cgatttacct gcaatatcca
      121 gccgttcatg ttgttggaac attccctgat ataaatccga aaaagcatct gtcgatctat
      181 agaaacagac tagaaagaca attgtactct tgtagctatc tgtcttagtt aacgttaaat
      241 aaattactgt tatggctaac attaataaac aagtcatcag tcttgccact aagtactgac
      301 taaaggaata tttttcatta atatctgttg cttgataatt acgaacctga aaaagtccaa
      361 caactaccat catattagca aaagaatagg caaaggcgta aatatctgaa tcagccgaag
      421 ttagtaacct agtaaccacc ataagtaata taactgatat tacagctgtt gataaacttc
      481 ctaacatatt ccataaaaaa atcgtttggt tttgttttga aggattaatc attggttttc
      541 tcttttttca taagggccac ttcttgggtc agacgtttta ctttatcatt ttgaagtgaa
      601 atattattag tcagtgaaaa aataatagct aaactcaaac aaaaacctaa aaagaataac
      661 atattggttg gtgaatgaat acccaggaag tgagacattt t
//
LOCUS       DAUGJR010000100          627 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUGJR010000100 DAUGJR010000000
VERSION     DAUGJR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.100"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(378..>627)
                     /gene="spej"
                     /locus_tag="VH800_001780"
     CDS             complement(378..>627)
                     /gene="spej"
                     /locus_tag="VH800_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeJ"
                     /protein_id="HEQ8362804.1"
                     /translation="TIQEFDFKIRQYLMQTYKIYDPNSPYIKGQLEIAINGNKHESFN
                     LYDATSSSTRSDIFKKYKDNKTINMKDFSHFDIYLWTK"
BASE COUNT          207 a           88 c           93 g          239 t
ORIGIN      
        1 ctagaaatat agacgaagtt aataaaatca ttgaagattt agaaaaaaac ttgcaagcac
       61 aataaagtaa agattaatcc agatatatat agtagcagag taattctcgc tgctttttat
      121 ttcaacgctt tacgtttatg gatacctcgc acagtaatga caagcgctct ttttggtact
      181 tttattgtcg taagaaatga agaaacgatt attttattag ccatagctac cctctagcca
      241 taaaaatacc tcttaagtag attttgatta tttaacctgt ctacttaaga ggtatcatat
      301 catattttat gagcggtttt atatttggta tcaatatctt atagggcaat tgatcatatt
      361 tattgaaagc tcctatctta tttagtccaa aggtaaatat caaaatggct gaaatctttc
      421 atatttatag tcttattgtc tttatatttt ttaaaaatat cactccttgt actagatgag
      481 gttgcatcat ataagttaaa actttcatgt ttattgccat tgatcgcaat ttctaattgc
      541 ccttttatgt atggagaatt aggatcataa attttgtatg tttgcataag atattgtctg
      601 attttgaagt caaattcttg aatcgta
//
LOCUS       DAUGJR010000101          512 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUGJR010000101 DAUGJR010000000
VERSION     DAUGJR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.101"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            108..374
                     /locus_tag="VH800_001781"
     CDS             108..374
                     /locus_tag="VH800_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8362805.1"
                     /translation="MTYFRLKKELNWSLRNKGIVVYEGNQKLQIAINTGKNNSEKVFF
                     DTFFEVVRAAATFSTAKNICFGLGLLRSQKQEIGYHISRVVHVF"
BASE COUNT          176 a           69 c           96 g          171 t
ORIGIN      
        1 ataggagggc aattgtttaa ctggttaatt agaatttttg ttattttcag gaagatactc
       61 agggcttttt tataagttga tgtattaaca aaagataaag aggtttcatg acttatttta
      121 gattaaaaaa agaattaaac tggtcactaa gaaataaagg aattgtagtt tacgaaggga
      181 atcaaaaact tcagatagcc attaatacag gtaaaaataa cagtgaaaaa gtcttttttg
      241 atactttttt tgaggtggtt cgggcggcag cgactttctc cacagcaaaa aacatctgtt
      301 ttggtcttgg cttacttcgt tcgcagaaac aggaaatcgg gtatcacatt agcagagtag
      361 ttcatgtttt ttgagcatca cactgggtct gtctacgttc taaaagcttt tgtcattttt
      421 gtatcatacc ccctacaagt agaaacagca taataaagaa aatttataaa caaaaatggc
      481 tagtattatc aaggaattta tcaatttttg tt
//
LOCUS       DAUGJR010000102          504 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUGJR010000102 DAUGJR010000000
VERSION     DAUGJR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.102"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
BASE COUNT          161 a           66 c           93 g          184 t
ORIGIN      
        1 gtaatcattt tttgatttac agttattatc atgtgttatc tggcgactgt cctgtttaca
       61 agtaagttca caagtatggg ataaaatagt ataaactata gtaaatactg aatagtcaaa
      121 gaaaaatatc ggcataggtc agaagagctg atatgtttaa tactttttgc ggatatctac
      181 tgtatttaaa tgtatttgat atccttgtca aggatatacg tctaaacaag ttcaaaacga
      241 aatcatttgt gattatctta tcaggagttg actcttgata agatttttgt atatcagtac
      301 tgtggtacgt ttagatagct tggcagtgaa tttatagagt gtcaaacaac gagtgttttg
      361 tgttacacta accattagaa gagtctattg ttgagcatat caaggtgtta tcttttcgag
      421 ttgaggtatc atatctagtt gtaatgtcaa acatatctag tatatttaac tatcacgcca
      481 aacgcatgca gaaacttttg tttt
//
LOCUS       DAUGJR010000103          419 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUGJR010000103 DAUGJR010000000
VERSION     DAUGJR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.103"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..353
                     /locus_tag="VH800_001782"
     CDS             <1..353
                     /locus_tag="VH800_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEQ8362806.1"
                     /translation="GIGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIE
                     SMHWLLDVVYHEDHHQTLDKRAAFNLNLIRKMCLYFLKVMVFPKKDLSYRRKQRYISV
                     HLEDYLVQLFGERG"
BASE COUNT          134 a           63 c           92 g          130 t
ORIGIN      
        1 gtggtattgg gatgactcgt aacacgattg ataaggatgg tcagctgagt caagagaatc
       61 gttattttat ctttagcttt aagccggatg tcctcacatt tgccaattgt gtacgaggtc
      121 attggcagat agagagtatg cactggttat tggacgttgt ttatcatgaa gatcatcatc
      181 agacattgga taaaagagcc gcatttaacc taaatcttat ccgaaaaatg tgcttatatt
      241 ttctcaaagt gatggtattt cctaaaaaag acctcagtta tcgtcgcaaa caacggtata
      301 tttctgtcca tttggaagat tatttagtcc aattatttgg agaaagaggc taagcagatg
      361 attgatttaa aaaggaatct tttcaaaatt gatgtccggg cacaaaagga tgaagagaa
//
LOCUS       DAUGJR010000104          403 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071815
            SAMN33608265-rid17959983.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUGJR010000104 DAUGJR010000000
VERSION     DAUGJR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608265
            Sequence Read Archive: SRR23751812
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723537.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723537.1
            Genome Coverage       :: 266x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:46:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,782
            CDSs (total)                      :: 1,741
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 28 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 15 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608265-rid17959983.denovo.104"
                     /strain="AUSMDU00071815"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
BASE COUNT          148 a           59 c           68 g          128 t
ORIGIN      
        1 gaaaaaagag gtcttcacca tggttaagca aatgatctta gtactaaggt taaaagatta
       61 tcgtgaaata aagttttgac acaagtgtaa ttaatagagg agcttgaagt atccggtaaa
      121 actatcttga agtgaacaaa cgagtaaacc tcccctgata aatacaatat actagccatt
      181 tcagagccat taagagtttc cagtgaagtg cttttgatag agagctaaga aaaaaacagt
      241 caaggtttaa gaactgcaaa ttagcattta aattattttt tgttaatgac agttgtcttt
      301 attaccataa ctataacttc ttataatata gtcttcttaa ttcatcagtg gtggttcgtc
      361 tcatatctga ccttaaaata ttaaactgat catcagatga tag
//
