LOCUS       DAUGOH010000001        94532 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUGOH010000001 DAUGOH010000000
VERSION     DAUGOH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 94532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94532
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.001"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            155..421
                     /locus_tag="VH957_000001"
     CDS             155..421
                     /locus_tag="VH957_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEQ8557956.1"
                     /translation="MLRDLLKGTLRFGQLKSSIGSVSQKVLTAQLRAMEADGLVHREV
                     YAEVPPWVEYSLTETGLSLAPVIEAMSDWGQTYQEKHADLFEEG"
     gene            complement(700..1413)
                     /gene="treR"
                     /locus_tag="VH957_000002"
     CDS             complement(700..1413)
                     /gene="treR"
                     /locus_tag="VH957_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEQ8557957.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            1624..3648
                     /gene="treP"
                     /locus_tag="VH957_000003"
     CDS             1624..3648
                     /gene="treP"
                     /locus_tag="VH957_000003"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEQ8557958.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPATEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFSAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANAIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSE
                     APAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDAFTVTVEGNLPHQIKANDKLVVAMKK"
     gene            3716..5344
                     /gene="treC"
                     /locus_tag="VH957_000004"
     CDS             3716..5344
                     /gene="treC"
                     /locus_tag="VH957_000004"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEQ8557959.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMGQGNGWNALFYNNHDQPRALNRFIDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAK
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILAEN"
     gene            5552..7447
                     /gene="pepO"
                     /locus_tag="VH957_000005"
     CDS             5552..7447
                     /gene="pepO"
                     /locus_tag="VH957_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEQ8557960.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGDHVPDDAILANFVKFHRLVADYAKRDEVGVSPILPLIAEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPNTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYS
                     KKVIDESLSLVENAQNLAKITIAHTWSKWSKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKINGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(7613..8653)
                     /locus_tag="VH957_000006"
     CDS             complement(7613..8653)
                     /locus_tag="VH957_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEQ8557961.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(8787..9554)
                     /gene="rpsB"
                     /locus_tag="VH957_000007"
     CDS             complement(8787..9554)
                     /gene="rpsB"
                     /locus_tag="VH957_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEQ8557962.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            9858..12932
                     /locus_tag="VH957_000008"
     CDS             9858..12932
                     /locus_tag="VH957_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8557963.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALIILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGCLESICL
                     EPFNRQESLAYINSQLGSQPVTEEEMEHLYQASQGTPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDVLLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMQE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTSGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIRQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(12963..13949)
                     /locus_tag="VH957_000009"
     CDS             complement(12963..13949)
                     /locus_tag="VH957_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginase family protein"
                     /protein_id="HEQ8557964.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSSSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYRMGYQKVCQTIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPK
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHN"
     gene            complement(14135..15676)
                     /gene="hutH"
                     /locus_tag="VH957_000010"
     CDS             complement(14135..15676)
                     /gene="hutH"
                     /locus_tag="VH957_000010"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEQ8557965.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGIACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLIEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KSENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(15687..17030)
                     /locus_tag="VH957_000011"
     CDS             complement(15687..17030)
                     /locus_tag="VH957_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEQ8557966.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNIGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVIFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(17250..17846)
                     /locus_tag="VH957_000012"
     CDS             complement(17250..17846)
                     /locus_tag="VH957_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEQ8557967.1"
                     /translation="MTTVMVKTPADYTQTDWSGGETNQLFLYPEKGDYKERTFSYRLS
                     TATVALRQTTFTRLDGYHRILMSLDKPITLSDLSHAKEISLAPFEPYAFEGDTRIVSR
                     GTCQDINLMYDDHYQGQLLPVWSDTLFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCPNQTSPAQTPVAVWAGLWYKT"
     gene            complement(17868..19541)
                     /locus_tag="VH957_000013"
     CDS             complement(17868..19541)
                     /locus_tag="VH957_000013"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8557968.1"
                     /translation="MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDAR
                     QLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYDADDSIETKLT
                     KIVTKVYGGKGITLTPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFI
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(19559..20185)
                     /locus_tag="VH957_000014"
     CDS             complement(19559..20185)
                     /locus_tag="VH957_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEQ8557969.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQAIITEIHAKSTALQASLLAAIDKDTEAFNLVSAVFDMPKETDEDKA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     SAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(20196..21095)
                     /gene="ftcD"
                     /locus_tag="VH957_000015"
     CDS             complement(20196..21095)
                     /gene="ftcD"
                     /locus_tag="VH957_000015"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEQ8557970.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATTKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTA
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEIIGLAPAKALIDV
                     AEYYLQVEDFDYHKQILENHLLG"
     gene            complement(21184..23214)
                     /locus_tag="VH957_000016"
     CDS             complement(21184..23214)
                     /locus_tag="VH957_000016"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEQ8557971.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPINEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWVTQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            23506..24771
                     /locus_tag="VH957_000017"
     CDS             23506..24771
                     /locus_tag="VH957_000017"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEQ8557972.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(24829..26361)
                     /gene="ahpF"
                     /locus_tag="VH957_000018"
     CDS             complement(24829..26361)
                     /gene="ahpF"
                     /locus_tag="VH957_000018"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEQ8557973.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHGSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     ADTANMTIIKNVATKDIVGDDHVTGLNYTERDSGEDKHLDLEGVFVQIGLIPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(26382..26942)
                     /gene="ahpC"
                     /locus_tag="VH957_000019"
     CDS             complement(26382..26942)
                     /gene="ahpC"
                     /locus_tag="VH957_000019"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEQ8557974.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            27349..27419
                     /locus_tag="VH957_000020"
     tRNA            27349..27419
                     /locus_tag="VH957_000020"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27381..27383,aa:Cys,seq:gca)
     gene            27938..28141
                     /locus_tag="VH957_000021"
     CDS             27938..28141
                     /locus_tag="VH957_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEQ8557975.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            28337..28798
                     /locus_tag="VH957_000022"
     CDS             28337..28798
                     /locus_tag="VH957_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEQ8557976.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            28798..31242
                     /locus_tag="VH957_000023"
     CDS             28798..31242
                     /locus_tag="VH957_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8557977.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSYGKLTFHIA"
     gene            31420..31710
                     /gene="groES"
                     /locus_tag="VH957_000024"
     CDS             31420..31710
                     /gene="groES"
                     /locus_tag="VH957_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEQ8557978.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            31746..33377
                     /gene="groL"
                     /locus_tag="VH957_000025"
     CDS             31746..33377
                     /gene="groL"
                     /locus_tag="VH957_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEQ8557979.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            33628..33894
                     /locus_tag="VH957_000026"
     CDS             33628..33894
                     /locus_tag="VH957_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8557980.1"
                     /translation="MNHFGEIFKTFRESKGLRLKDVAKAGISTSQLSRFEKGETDLTI
                     STFMLILDESNMSIDEFMYAVHDFHRDDLNELLSKSEGFRNNSR"
     gene            complement(34622..36121)
                     /locus_tag="VH957_000027"
     CDS             complement(34622..36121)
                     /locus_tag="VH957_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8557981.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVEEKPKNKKGLNRS"
     gene            36368..38008
                     /locus_tag="VH957_000028"
     CDS             36368..38008
                     /locus_tag="VH957_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8557982.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLISGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(38097..39098)
                     /locus_tag="VH957_000029"
     CDS             complement(38097..39098)
                     /locus_tag="VH957_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8557983.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            39674..40054
                     /locus_tag="VH957_000030"
     CDS             39674..40054
                     /locus_tag="VH957_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8557984.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            40093..42429
                     /locus_tag="VH957_000031"
     CDS             40093..42429
                     /locus_tag="VH957_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8557985.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKARLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            42478..42630
                     /gene="rpmG"
                     /locus_tag="VH957_000032"
     CDS             42478..42630
                     /gene="rpmG"
                     /locus_tag="VH957_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8557986.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            42644..42820
                     /gene="secE"
                     /locus_tag="VH957_000033"
     CDS             42644..42820
                     /gene="secE"
                     /locus_tag="VH957_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEQ8557987.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(43056..43829)
                     /locus_tag="VH957_000034"
     CDS             complement(43056..43829)
                     /locus_tag="VH957_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEQ8557988.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            43955..44701
                     /locus_tag="VH957_000035"
     CDS             43955..44701
                     /locus_tag="VH957_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8557989.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKVITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            44717..45697
                     /locus_tag="VH957_000036"
     CDS             44717..45697
                     /locus_tag="VH957_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEQ8557990.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRKQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            45985..46305
                     /locus_tag="VH957_000037"
     CDS             45985..46305
                     /locus_tag="VH957_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8557991.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            46333..46641
                     /locus_tag="VH957_000038"
     CDS             46333..46641
                     /locus_tag="VH957_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8557992.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIQMADYGMLDGNKVLDLALSLVKE
                     "
     gene            46651..47955
                     /locus_tag="VH957_000039"
     CDS             46651..47955
                     /locus_tag="VH957_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8557993.1"
                     /translation="MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSDVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGLIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQATEES"
     gene            48166..50583
                     /locus_tag="VH957_000040"
     CDS             48166..50583
                     /locus_tag="VH957_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEQ8557994.1"
                     /translation="MTETKSPYFGHLTDRMAHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKEMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGQLTPEELWHALESDFAGERGEDIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            50596..51264
                     /locus_tag="VH957_000041"
     CDS             50596..51264
                     /locus_tag="VH957_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8557995.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYKGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     DSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            51321..52409
                     /locus_tag="VH957_000042"
     CDS             51321..52409
                     /locus_tag="VH957_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEQ8557996.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNSMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(52491..53000)
                     /locus_tag="VH957_000043"
     CDS             complement(52491..53000)
                     /locus_tag="VH957_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEQ8557997.1"
                     /translation="MSTDHHLREVSYQLLAERGGSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGYSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            53363..54178
                     /gene="sdaB"
                     /locus_tag="VH957_000044"
     CDS             53363..54178
                     /gene="sdaB"
                     /locus_tag="VH957_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEQ8557998.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(54419..55261)
                     /locus_tag="VH957_000045"
     CDS             complement(54419..55261)
                     /locus_tag="VH957_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8557999.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            55760..55930
                     /locus_tag="VH957_000046"
     CDS             55760..55930
                     /locus_tag="VH957_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558000.1"
                     /translation="MDNPKKDKGLSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            56202..57398
                     /gene="speB"
                     /locus_tag="VH957_000047"
     CDS             56202..57398
                     /gene="speB"
                     /locus_tag="VH957_000047"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEQ8558001.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDVNGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            57400..57705
                     /locus_tag="VH957_000048"
     CDS             57400..57705
                     /locus_tag="VH957_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEQ8558002.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMVEAYQKQINSLD"
     gene            58185..59114
                     /gene="prsA"
                     /locus_tag="VH957_000049"
     CDS             58185..59114
                     /gene="prsA"
                     /locus_tag="VH957_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8558003.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(59385..59621)
                     /locus_tag="VH957_000050"
     CDS             complement(59385..59621)
                     /locus_tag="VH957_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558004.1"
                     /translation="MIHRFFLTPLSTLWRRLRPKRYSKKVLADEPTGYQPPAAHGPCD
                     ETHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            60045..63071
                     /locus_tag="VH957_000051"
     CDS             60045..63071
                     /locus_tag="VH957_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8558005.1"
                     /translation="MTNCKYKLRKLSVGLVSVGTMLIAPTVLGQEVSTGASSTETSAS
                     TNTSTASAGTSTSETAASGTGSEAAVVSSEGSQSSESGQASTQPQAQTLEQSAATSPS
                     SNSSTSSSEDKAPKAASTKSSSATVASSSNGSNQGAGAEDAPQMMDVERYTVDREKTE
                     LNIKDGKTPKTRNSVDKDTKLIRNRDGKQRDIVDIKREVKDNGDGTLDVTLKVTPKEI
                     DKGADVMALLDVSKKMTDADFKNAKDKIKKLVTTLTSKSASNSDNDEHKHNSRNSVRL
                     MTFYREISNPIDISGKTDAELDKLLDDLRVKAKANYDWGVDLQGAIHKAREIFNKEKE
                     SKKRQHIVLFSQGESTFSYDIQKSEKEKSSNLSRINEKITSSNPLLPWPPIFDHTHQN
                     GDMINDVRALIAFASKLGIKNLSWIETSLSALSVGSNLLGSVFGGGGLGEYLTLKEYD
                     SQKLNEDQFDYTKRVGEGYHYHSFSNRESEDKMPLETEIKKALEAALPKFEENNWFTK
                     VLKYFGLKDKAEQAKLDVIMKVIKSVFYKRQYHYYNHNLSAIAEAKMAQKEGITFYSV
                     DVTALNTARRVKRQTAVLKNTKEEERNKKFDEYLKKMSEGGNAFFNDVDKADKFKDTL
                     TKLTIKDEFDGKVSVDKTSYQSSSAINYSEASNSFWRTTKESLTWTISKEQLKKAFED
                     GKPLTFTYKLKVDNNKFKTALEENNKKKRTKRSTPTENENSVTEKIISNTTTYEINEQ
                     KVEGNKLGDVSLTYSKFKVPVPQIDGHVIEPQAPTLPKLPPVIEHGPNFEYEEETGYQ
                     LPLKHGSNAPDTQVTIEEDTVPQRPDILVGGQSGPVDITEDTQPGMSGSNDATVVEED
                     TAPKRPDVLVGGQSEPIDITEDTQPSVSGSNDATVVEEDTVPQRPDILVGGQSDPIDI
                     TEDTQPGMSGSNDATVIEEDTKPKRFFHFDNEPQAPEKPKEQPSLSLPQAPVYKAAHH
                     LPASGDKREASFTIVALTIIGAAGLLSKKRRDTEEN"
     gene            63251..65212
                     /locus_tag="VH957_000052"
     CDS             63251..65212
                     /locus_tag="VH957_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8558006.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAISNRLEYQEQYKRVKEE
                     LDALKEKSPKLGERSLYFRLVNRFLGWFGVVWDPLAIKETDHLLDLIGQVNYLVSNTE
                     FQAPEYQKAKNKLDLAVAGYDLYLAREKKRGDAPDYQVTQLTLGQLETIKTKIQEALK
                     TFAQEVKTIQQKTPDLFPHAYVLNAKTSAIDGKAQPFLVNGYYDVFYKQFLFTNKNDG
                     YNYNKEADNLTSYQNLIKELLDLKAEIDRLTKDDPKNDRLETLMWQSKFTLSDFRRTS
                     RLSAYYTQGDYVKTVVLSEEAPNLRTAKEKVKTLKGILHDYYVETNKPEKAKEYRVED
                     ETLPSQPEAPVTPEAPAPSPVPGQKPAEAERSSQATEPANPSKENSSTDASQGSHDSE
                     NPATDSPSQPQAPDQGNHQSQVPNDKPQTDKTDTPNVPAPPQNTPNAPAIPQDTPKVP
                     EAGGQSGPAGNAEEKAPDSGPKASDQSSSKESPSVGEDTTPNQPDVLVGGQSEPIDIT
                     EDTITDAPPTVSGHNASTQPQSVVEDTAPQRPDVLVGGQSEPIDITQDTQPGMSGSND
                     ATVINEDTKPKRVFHFDNKEPQASEKAAEQKLAPHDSHTTPQASDDTAAPHLPASGDK
                     PEKAFALAALTMVAAAGLLSKKRRNTDKN"
     gene            65354..65650
                     /locus_tag="VH957_000053"
     CDS             65354..65650
                     /locus_tag="VH957_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEQ8558007.1"
                     /translation="MTKQDQLIVEKMEQTYETFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            65799..66083
                     /locus_tag="VH957_000054"
     CDS             65799..66083
                     /locus_tag="VH957_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEQ8558008.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            66507..67775
                     /locus_tag="VH957_000055"
     CDS             66507..67775
                     /locus_tag="VH957_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8558009.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATAATEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            67762..68436
                     /locus_tag="VH957_000056"
     CDS             67762..68436
                     /locus_tag="VH957_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558010.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            68449..69666
                     /locus_tag="VH957_000057"
     CDS             68449..69666
                     /locus_tag="VH957_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558011.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            69760..70413
                     /locus_tag="VH957_000058"
     CDS             69760..70413
                     /locus_tag="VH957_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8558012.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            70410..71798
                     /locus_tag="VH957_000059"
     CDS             70410..71798
                     /locus_tag="VH957_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8558013.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            71900..73528
                     /locus_tag="VH957_000060"
     CDS             71900..73528
                     /locus_tag="VH957_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8558014.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTAD
                     TDTDDESETAKKDKKSKETASQHDTQKDHKSSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSAEKT
                     PEKGPEKATEKTPEPNRDAPKPIQPPLAAAAPVFAPWRESDKDLSKLKPSSRSSAAYV
                     RHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVR
                     AIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIAN
                     KNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTP
                     EIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVD
                     RYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILIS
                     ESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP"
     gene            73606..73857
                     /locus_tag="VH957_000061"
     CDS             73606..73857
                     /locus_tag="VH957_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558015.1"
                     /translation="MIKKVTTPSQKIKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            74533..76125
                     /locus_tag="VH957_000062"
     CDS             74533..76125
                     /locus_tag="VH957_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8558016.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKDCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGCAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQRDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIE
                     KQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSP
                     SKSHSDKEVQKPDNSVKQATSS"
     gene            76312..77589
                     /gene="mrp"
                     /locus_tag="VH957_000063"
     CDS             76312..77589
                     /gene="mrp"
                     /locus_tag="VH957_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Mrp"
                     /protein_id="HEQ8558017.1"
                     /translation="MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAETV
                     GRFSDEQVRKAREKAIEDVFDGYTGARSVYQSGNLPNRLTPTKLSKLMQQMYKETLQK
                     KEELDTLSKALTHTIEKKIESENAYKKELGQLKAAAEAEAQKALDALNNKNKQISDLT
                     NENAQLKEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEE
                     IAKLQSEAATLENLLGSAKRELTELQAKLDTATAEKAKLESQVTTLENLLGSAKRELT
                     DLQAKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKAL
                     KEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLP
                     STGEETTNPFFTAAALTVIASAGVLALKRKEEN"
     gene            77814..78917
                     /locus_tag="VH957_000064"
     CDS             77814..78917
                     /locus_tag="VH957_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407885.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEQ8558018.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTTVKADSD
                     NINRSVSVKDNEKELHNKIADLEEERGEHLDKIDELKEELKAKEKSSENVERHYLRKL
                     DQEYKEQQERQKNLEELERQSQREVEKRYQEQLQKQQQLETEKQISEASRKSLSRDLE
                     ASRAAKKDLEAEHQKLKEEKQISDASRQGLSRDLEASREAKKKVEADLAALTAEHQKL
                     KEEKQISDASRQGLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEK
                     EKAELQAKLEAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQKRTL
                     PSTGETANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            79127..80233
                     /gene="enn"
                     /locus_tag="VH957_000065"
     CDS             79127..80233
                     /gene="enn"
                     /locus_tag="VH957_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Enn"
                     /protein_id="HEQ8558019.1"
                     /translation="MARQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRAEGV
                     KATTNLPEEAKYAALKDENTGLRGDQTKLVKKLEEEQEKSKNLEKQKQELENQALNFQ
                     DVIETQEKEKEDLKTTLAKATKENEISEASRKGLSRDLEASRAAKKELEAKHQKLEAE
                     NKKLTEANQVSEASRKGLSNDLEASRAAKKELEAKYQKLETDHQALEAKHQKLETDYQ
                     VSETSRKGLSRDLEASREANKKVTSELTQAKAQLAALEESKKLSEKEKAELQAKLDAQ
                     GKALKEQLAKQTEELAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPSQNKGMRSQ
                     LPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            80568..84116
                     /gene="scpA/B"
                     /locus_tag="VH957_000066"
     CDS             80568..84116
                     /gene="scpA/B"
                     /locus_tag="VH957_000066"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEQ8558020.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTAVSEEAPSSSKETNPPQIPDDAEETVADKANDPAPQAPAKTADTPVTSKAT
                     IRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA
                     KKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEG
                     AMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDET
                     KKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSP
                     DKQLTETATVKTADKQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALI
                     ERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDN
                     PKKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAK
                     LSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYF
                     SPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDTFEVTVTVHNKSDKPQELY
                     YQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMK
                     NGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSD
                     AKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGT
                     FAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGN
                     VVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPIS
                     SGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDE
                     DLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLE
                     GHSNKPEQDGSDQAPDKKPETKPEQDGSGQAPDKKPEAKPEQDGSGQTPDKKPEAKPE
                     QDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTRDQLP
                     TTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED"
     gene            84213..85448
                     /locus_tag="VH957_000067"
                     /pseudo
     CDS             84213..85448
                     /locus_tag="VH957_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            85700..86620
                     /gene="lmb"
                     /locus_tag="VH957_000068"
     CDS             85700..86620
                     /gene="lmb"
                     /locus_tag="VH957_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEQ8558021.1"
                     /translation="MKKGFFLMAMAVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            86633..89104
                     /locus_tag="VH957_000069"
     CDS             86633..89104
                     /locus_tag="VH957_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEQ8558022.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGPATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNP
                     GQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGL
                     IFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDHSK
                     PSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHY
                     IGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVG
                     YMMSKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLP
                     MHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHE
                     ESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETF
                     VWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQAD
                     KSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQP
                     EGVQFYNKNGELVTYDIKTLQQINP"
     gene            89273..89473
                     /locus_tag="VH957_000070"
     CDS             89273..89473
                     /locus_tag="VH957_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8558023.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(89553..90179)
                     /locus_tag="VH957_000071"
     CDS             complement(89553..90179)
                     /locus_tag="VH957_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558024.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHDFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(90163..90966)
                     /locus_tag="VH957_000072"
     CDS             complement(90163..90966)
                     /locus_tag="VH957_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558025.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(90978..91799)
                     /locus_tag="VH957_000073"
     CDS             complement(90978..91799)
                     /locus_tag="VH957_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558026.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(91796..92773)
                     /locus_tag="VH957_000074"
     CDS             complement(91796..92773)
                     /locus_tag="VH957_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558027.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVIRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNFIADILNSIINPQLRRKV"
     gene            complement(92886..94514)
                     /locus_tag="VH957_000075"
     CDS             complement(92886..94514)
                     /locus_tag="VH957_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8558028.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGIHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT        30289 a        18674 c        19644 g        25925 t
ORIGIN      
        1 catttatcag ccctatcttg tttctgttct ctctaatagt ctataatggg ttataagtta
       61 caaaaagata ctaagaggag ctgctgccta tgctgaaaaa aagaccggct tgtcccgtag
      121 aaacgacctt atcggtaata aatagaaatt gttaatatta agagacttgc taaaggggac
      181 cttgcgtttt gggcagttga agtcctcaat aggttcggtc agtcaaaagg tccttactgc
      241 ccaattaagg gctatggaag cagacggatt ggttcatcgg gaagtgtatg cagaagtgcc
      301 accttgggtg gagtattcct taacagaaac tgggttgagc ttagctcctg ttattgaagc
      361 gatgtcggat tggggccaaa cttaccaaga aaaacatgcc gatttatttg aagaaggcta
      421 gaggaaagag ttgcccgagc atactgagac cgagagaagc tgagagtttt taaaaaatga
      481 tattatcaaa ttctttacag tttgataaaa ttactttttt tctacaaaaa gacttgcgct
      541 catctcacga atatgataat ataatatcaa gtatgtttga gaaaacagaa gctcaggtca
      601 agtaagtgca cacttacaat aacacagttg ataatgggga aactcagagt caagaaaaag
      661 aaaagcaagc cttgcatttt gcaaggcttt tttctgtctt tattttggtc tgcgccgagc
      721 aaaatctaaa aatttaaatt tttccagttt atggcgactc tcggtgaatt ggaattggtt
      781 attattggaa aggtagactt tggatttgac ggaaacaaca tgttggtctg atccaaggtc
      841 aagtaaaatt ttatcacgat cggttatttg gtcaatggta acctctttga gggcaaagtc
      901 aatggcgaga tggagttcct tttccaaata ttgataaata gaatgctctg cgatttccct
      961 tgtcattatt ggcaccaaag ttttactaag gtaatcaatg tctaagacgg aagccacacc
     1021 ctcaacaacg cgttggcgcg taacacgcca gaccaagctg tttttgctaa aaccggtcaa
     1081 ttttgaaagt gtctcatcca caatcagttt atcaatggca atgacgttgg tcttagaatc
     1141 tagatttgag taagagacga gttcctgata actagttagt tctgagatag ggaacatgat
     1201 ctgatgatgt ctaatcactt gggtgccacg tccttgtttt ttgaggataa gacctgcctt
     1261 tgtgagaagt gagagagcct tgcggacggt atctcggcta gcttggtatt gttgactcaa
     1321 ttctatttca gtaggtaaaa aatccccttc tttgtaaaag tctttgttta tttttgtttc
     1381 gaggtcttta taaatacgtt catactttgt catagggtaa attacctttc cacttgtcta
     1441 tttttttaca gacaacacct tttattttac caaaataatg gcttttttgg cacaaacaac
     1501 ttgcagacaa atttgcaatc gattacaata aaggtgtcaa tcaggttcta tctaagaatt
     1561 tgaatatttc attttgacgt tgcttgttaa aagcaactag aacaaaggac taggggatgt
     1621 cacatgggaa aatttgaaca ggatgctaaa agtcttctaa ctgctattgg cggtaaagaa
     1681 aacatcaagg ctgtcacaca ctgtgcaacg cgtatgcgtt ttgttttgaa tgataataat
     1741 aaggcaaatg tcaaagagat tgaaaaaatc tctgtagtta aagggacatt taccaatgct
     1801 gggcagtttc aggtaatcat tggtaatgat gttccagttt tttataatga ctttacagct
     1861 gtttctggta ttgaaggggt gtctaaagaa gctgccaaat cagcagctaa aagtaatcaa
     1921 aatgccttac aacgggtgat gaccatgttg gctgagattt tcacacctat tattccggcg
     1981 attattgttg gggggcttat tttaggtttc cgtaatattt tggagagtgt gccttttgaa
     2041 tttcttgggc agcaggtcga aaaagggaaa ttagtttttg atgcagctgg ggatcctgtt
     2101 tggaatacga ttgtgagggt atctcctttc tggtcagggg ttaaccattt cttgtggtta
     2161 ccaggggaag ctattttcca cttcttacca gttgggatta cttggtctgt gacgcgtaag
     2221 atgggaacca ctcaaatttt agggattgtc cttggtatct gtttggtgtc gccacaatta
     2281 ttgaatgcct atgcggtggc aggaacgcct gctactgaga ttgccaaaaa ctgggtttgg
     2341 gattttggtt tctttactat taatcgtatt gggtatcagg cacaggttat tccagccctt
     2401 ttagctggtc tgtcccttgc ttatcttgaa attttctggc gtaaacggat tccagaagtg
     2461 gtttcaatga tttttgtgcc attcctttct ttgattccag ctttgatttt agcgcatacg
     2521 gtattggggc caatcggttg gactattggt aaagggattt cctttgttgt gttagctgga
     2581 ttgactggtc ctgttaaatg gctattcagt gctatctttg gtgccttgta tgctccgcta
     2641 gttattactg gtttacatca catgacaaat gccattgata cccaattaat tgctgatact
     2701 gcaactcgta caactggttt gtggccaatg attgctcttt caaatatcgc tcaagggtca
     2761 gccgtttttg cttactattt aatgaatcgt catgaagaac gtgaggctga aatatcgctt
     2821 cctgcagcaa tttctgctta ccttggggta actgagcctg ctttatttgg ggttaatgtt
     2881 aaatacgttt atccctttgt agccggaatg attggctcag gtattgcggg tctcttatca
     2941 acaaccttta atgttcaggc aaatgctatt ggtgttggtg gcttaccagg tttcatggct
     3001 atcaatgtga agtacatgat tccattcttc atctgtatgg cagtagccat tgtggtaccg
     3061 atgtttttaa ccttcttttt ccgtaaatca catatcatga ctaagacaga agatgaggct
     3121 aaactacctg agacacccgt ttcggaggct cctgcagcaa ctgctccaca taagactatg
     3181 caagggacag ttatcacttt aacaagccct ttaacgggtg aagttaaagc gttgtctgaa
     3241 gctgttgatc ctgtctttgc acagggagtt atgggccaag gtgctcttct tcaaccgaca
     3301 gaaggggtgt tagtagcgcc ttgtgatgct gaagtatcgg tcttgttccc aactaaacac
     3361 gctatttgtt tggtgacgac tgaaggtttg gaattattga tgcatattgg catggatacg
     3421 gttaacttag atggtcaagg atttgaagct ttggtgaagc aaggtgatca ggttaaggct
     3481 ggacaaacat tgattcaatt tgatatagca gctatttctg aagctggata cgccactgaa
     3541 acgcctcttg tggtgactaa tcaagatgct tttacggtaa ctgttgaagg taacttaccg
     3601 catcagatta aggctaatga taagttagta gtagcgatga aaaagtaggt ttactaggga
     3661 gaaaacgttc aggaactgag atcagttcct gaaactattt tagggaggaa aactcatgac
     3721 aattgataaa aagaaagtcg tctatcaaat ttacccaaaa tcctataagg acactactgg
     3781 aaatggtgtg ggagacttgc gagggatcat tgataaattg ccttacttac aagaactagg
     3841 aatagatatg atttggttga accctttcta ccctagtcca caacgagaca atggctatga
     3901 tgtttcagat tatacggcgg tcaaccctga ttttgggacg atggctgatt ttgaagattt
     3961 ggtaaaagct gctaaggagc atcagattga gttaatgttg gatatggttt tgaatcactg
     4021 ttccacagac cacgagtggt tccaaaaagc tttagcagga gacccttatt atcaggattt
     4081 ctttatcttg agagatcagc cgactgattg ggtttccaaa tttggtggga atgcttgggc
     4141 gccttttgga gatacaggca agtactactt acacttgttt gatgtgacac aggctgactt
     4201 gaattggcgg aacccacatg ttcgtgagga attggctaaa gtggttaatt tttggcgaga
     4261 taaaggagtg aagggattcc ggtttgatgt gattaacctg attgggaaag atgaagagct
     4321 ggtggattgt ccggtcaatg atggtaagcc agcttatacg gatcgtccta ttactcacac
     4381 ttatcttcat gatctcaatc aagccagttt tggtcaggat gattcgttta tgacagtagg
     4441 ggaaatgtct gccacgacta ttgacaactg tcttttatac acggctcccg aacgtgagga
     4501 gctatccatg gcttttaatt tccaccatct aaaagttgat tatgagaatg gtcagaaatg
     4561 gactattatg gcttttgatt ttgcagcgct gcgagactta ttccatgctt ggggtgaagg
     4621 catgggtcag ggcaatgggt ggaatgcctt gttctacaat aaccatgatc aaccacgtgc
     4681 cctgaatcgt tttattgatg taacacattt ccgaaacgaa ggtgcgacga tgttagcggc
     4741 ttccatccat ttgtcacgag gaacgcctta catttatatg ggtgaggaga ttggcatgct
     4801 tgatccagat tttgatagta tggatgatta tgtggatgtg gaaagtctca atgcttactc
     4861 aagcttatta gtctcaggta aaagtgcgaa agaagccttt gccattatca aggctaagtc
     4921 aagggacaat gccagaacac caatgcaatg ggatgctagt gaacatgctg gctttacgac
     4981 tggtaagcct tggttagagg ttggcaaatc ttatcgagac atcaatgtcg aaacagaaaa
     5041 agaaggacgt atttttcctt tctaccaacg cttgattgct ttgcgtaagg aactccctat
     5101 tattgctgaa ggggactatc gggctgcttt taaagatagt caggctgtct acgcctttga
     5161 acgccattta ggtgaccagt gtttgcttgt tctcaatcat ttctatgctg atgaggtcga
     5221 actggaatta cctccacgtt atcaacatgg acaggtctta atcagcaact atgagaaagt
     5281 ttctatttgt gaaaaagtga tactgaaacc ttatcagaca cttgctatct tagctgaaaa
     5341 ctaactaaaa gcctgaggtt aggcctcagg cttttggtga ttgtcacgaa aaaagaagtt
     5401 ttctcatata tttattttta aactcttatt ttttctaaat aaaaacaatt gagataagtt
     5461 attttagcta aattttggta caatggaaaa gattataagt agagtttaag ataaagattc
     5521 tacaaattta aaatgatata aggagatacg aatgacaact tatcaagatg atttttacca
     5581 ggctgtgaat ggaaagtggg ctgaaacagc agttattcca gacgacaagc ctcgaacagg
     5641 tggattttca gacttagcag atgaaattga ggcattaatg ctagacacta cagatgcttg
     5701 gttagcaggg gatcatgtcc ctgatgatgc aattttagca aactttgtga aattccatcg
     5761 tttggtggct gactacgcta aacgtgatga agttggagta agtccaattc ttcctttaat
     5821 tgcagaatat cagtccttaa aatctttttc agaatttgtt gctaatatag cgaaatatga
     5881 attggcaggt ttaccaaatg aatttccctt tagtgtggca ccagacttta tgaatgctca
     5941 gctgaatgtg ctttgggcag aagcaccaag cattcttttg ccaaatacaa catactacga
     6001 agaaggcaac gaaaaagctg aggaattgcg tggtatttgg cgtcagtcgc aagaaaagct
     6061 tttacctcaa tttggttttt caacagaaga aatcaaggat cttttggata aggtaattga
     6121 gctagataag caattggcca agtatgtctt gtctcgtgag gaaggctcag aatatgccaa
     6181 attataccat ccttatgtgt gggctgattt taaaaaacta gctccagagc ttcctttgga
     6241 tagcattttt gaaaagattt taggccaagt acctgacaag gttattgttc ctgaggaacg
     6301 tttttggaca gaatttgcag ccacttatta ctctgaagcc aattgggatt tactcaaggc
     6361 taatttgatt gtggacgcgg ctaatgctta caatgcttac ttgacggatg atattcgtgt
     6421 ggaatcaggc gcttattcgc gcgctctttc aggaacacct caagctatgg acaaacaaaa
     6481 agcagccttt tatttggcgc aaggaccgtt tagccaagcg cttggcttgt ggtatgctgg
     6541 tcaaaaattc tccccagaag ctaaggctga tgtggaaagt aaggtagcac gcatgattga
     6601 ggtttataag tctcgtctag aaacggctga ttggttagca ccagccacac gtgaaaaagc
     6661 cattactaaa ttaaatgtta tcacgccaca tattggttac ccagaaaaat taccagaaac
     6721 ctattctaaa aaagtgattg atgagagctt gtcattggtt gaaaatgcac agaacttggc
     6781 taaaatcacg attgctcaca cttggagtaa atggagcaag ccagttgacc gtagtgagtg
     6841 gcatatgcca gcccacttag tcaatgctta ttatgatcct cagcaaaatc agattgtctt
     6901 tcctgcggca atcttacaag agccatttta ttctttagat cagagttctt cagccaatta
     6961 tggaggaatt ggtgcagtca ttgcgcatga gatttcacat gcctttgaca ccaatggtgc
     7021 ttcctttgat gaacatggta gcctaaatga ttggtggaca caagaagact atgctgcctt
     7081 taaagagcgt acagataaga ttgtggcgca gtttgacggc ttagagtcac atggtgctaa
     7141 gatcaatggt aaattgacag tttcagaaaa cgtcgctgat ctaggtgggg tagcttgtgc
     7201 tttagaagcg gcacaatcag aagaagactt ctcagcccgt gacttcttta ttaactttgc
     7261 gacgatttgg cgtatgaagg cccgtgagga atacatgcaa atgctagcta gcattgatgt
     7321 tcatgccccg ggtgaactgc gaacaaatgt caccttaacc aactttgatg ctttccatga
     7381 gacctttgat attaaagaag gcgatgctat gtggagagct ccgaaagacc gtgtgattat
     7441 ttggtaatta ggtagttgat aaaccttcaa atgcttgtga ttataaaaat gactgattct
     7501 gtgaaacaca ggatcagttt tttgcttcct tattggtgtc cgttttgaca caacaaaaag
     7561 acaaccctca ggaaagaagg tcgccttttt tagacttatc agaaataagt gattagttgt
     7621 taagggcagc agccatagta gctgcaactt ctgattcaaa gtcgttagct tttttctcga
     7681 taccttcacc aacttcaaaa cgtgcaaaag caatcgcttt agcgtttact gagtcaaggt
     7741 aagcttcaac agttttgctg tcgtccatga tgtaaacttg tgcaagaaga gtgtaagctt
     7801 ggtcaacttt agtgttgtca agcatgaagc ggtccatttt acctgggatg attttgtccc
     7861 agatcttttc tggtttgcct tcagcagcaa gttcagcttt gatgtctgct tcagcagcag
     7921 taatcacgtc gtctgataat tgagcttttg aaccgtattt caagaatgga agtgctggtt
     7981 tgtcaaccat tgcacgcgat tcgttgtcaa gttcgatagc gtggttcaat tgagcaagtt
     8041 catctttgat gaattgtgca tcaagctcag tgtatgaaag aacagttggt ttcattgcag
     8101 cgatatgcat tgatacttgt ttagcaagag catcgtcgcc gccttcgaca actgagataa
     8161 ccccgatacg gccgccatta tgttggtaag caccgaagtg ttgctcatct gttttttcaa
     8221 tcaaagcaaa acgacggaat gagatttttt ctccgatggt agcagttgca ttaacgtaag
     8281 cttcagcaag agtttcacct gaaggcataa caagtgcaag tgcttcatcg ttgttagctg
     8341 gtttgccttc agcgataact ttagcagttg cgtttaccaa ttcaacgaat tgagcatttt
     8401 tagcaacaaa gtctgtttca gcgttaactt caacaacagc agcaacgtta ccatgaacgt
     8461 aaacgcctgt taaaccttca gcggcaacac ggtcagcttt tttagctgct ttagccattc
     8521 ctttttcacg aagaagttca acggctttgt ccatgtcacc atctgtttca acaagtgctt
     8581 ttttagcgtc cataacgcca gcaccagatt tttcacgtaa ttcttttaca agcttagctg
     8641 taatttctgc catgtgtagt atcctccaaa tgatatttgt tttggtttca aaaaacgaga
     8701 cagagcggtt tgctttctgc cccgtttggt tttcgattgt taaagacaaa caaagtttgc
     8761 cataagagtt aggaactctg tgctaattaa gcgttgtcgc cttcgacaac ttcaacgatt
     8821 tcttcgattg aatctgcttg agtgtcagct tcaaaagcaa cgtctgcatc ttcaccttga
     8881 cggccttcga taatagcatc agctaattta gcagtgatta atttaacggc gcggatagcg
     8941 tcatcgttag ctggaatgat gatatcgata tcatctggat cagcgtttgt atcaaccatc
     9001 gctacgactg ggataccaag ttttttagct tctttaacag caatttgttc tttatgtggg
     9061 tcaacaacat acatcacgtc tgggatacga ggcatatctt cgataccgcc caagaatttt
     9121 tcaagacgag cgcgttgttt gttaagaagt gcaacttctt tcttaggaag aacgtcaaag
     9181 gttccttctt cttccatacg tttgatttct ttcaaacgag cgatacgttt ttggatagtt
     9241 ccccagttgg taagcgttcc acccaaccaa cggtggttga tgaagtattg gcctgcacgc
     9301 gttgcttcgt cagcaactgc ttcagcagct tgttttttag taccaacgaa caagatgaca
     9361 gcatcgtttg ctgcagcatc acgaacaaat tcgtaagctt ggtcagctaa ttttacagtt
     9421 tgttgaagat cgataacgtg gataccgtta cgctctgtga agatgtattt agccatctta
     9481 gggttccagc gacgagtttg gtgaccaaag tgaacaccag cctcaagaag ttgtttcatt
     9541 gaaattactg ccatgagtag tttctccttt ataaaatgtt ttttcctctt ccagacttcg
     9601 acttgcaggc taacctagcg gcaacaagcc cacaattggt ctagaatgag tatttgccgt
     9661 ctacacgacc ctactatatt atcaaaaaaa gaggttaaaa gcaaggagaa atgctatgaa
     9721 ttcccttatt ttcgagatga ctagcttctt tgtttattgg taagtgttaa gacaagcttt
     9781 tgctcatttt gggtgacact tgccaaatcg ttttatttaa gatatagtga acttgactaa
     9841 tttttggagg cgttttcatg acgaagggta ttcgatttca attgcttggc agtccccaca
     9901 tttttcttga tgacaaagaa caattttttg cctttgccaa agcaaatgct ctcctttatt
     9961 acttagtggt taatggatct gttagccgcg aggtggcggc gagtctactt tgggaaaata
    10021 agaacacgca aacagcgaaa aagaatttac gaaacgctat ctaccaggtc aataaagtct
    10081 tgcaagctga tgtgattatt tgtcccaatc gcaacctgct ggttttgaat aaaacacttg
    10141 atatcaaaac agatattaac ctttttctgg ctgatccgct agctcactta gaactctacc
    10201 aaggggagtt tttgcagggc ttttacctta aaagtggtga ggaatttgat ctttgggttt
    10261 caaaaatgcg tatgcagtat gaacaggtat acctaaaagc gtgttaccaa aaaattgaag
    10321 aaaagctctc tttagatgcc attgaagatg tcgaggaaca tttaaaacag cttattgaac
    10381 gtgatgaatt tgaagagaaa aattatcagc tcttgatgag gctttatcag caggggaatt
    10441 gtcctggtaa ggtcatcgaa acttattatc agttggctaa tgtgttggat aaggagctag
    10501 ggattcagcc aagtttgcaa agccaacaga tttatcagga agtggtcgct aaagatcgta
    10561 atgaacgcaa aatcaagcat tttttgcgca acagtaatca ttttttgggg cggattgatg
    10621 agattaagca gctggaaaac tattttgcca actgtttggc ctgccaagag gtaggagctc
    10681 tgctcttaat tggtgataca gggattggga aacgaaccct agccagacag gtcttagcca
    10741 atcaaaccca aacgtttcaa attgtcacag ctaaatgttt tcgtgaagag gctatggatt
    10801 ccttattgcc ttggcgtaat atcttagatg gcctgggaga tttggtgatt caaaaccgct
    10861 tattgaccac caaagcttgg aaggctgctc ttaaacgctg ttttcctgtg gcaaccattt
    10921 ttcaagaaga taacaaccaa ccctttatca aggaccacac cagcttgttg gtttccttta
    10981 ttgttgatat tttacaacat ttggcagaaa tcaaggcgct gataatcctt attgaggatt
    11041 gtcattggat ggatgaggac agtttgacct tgttgcaacg ggtcatgaat caattggtcc
    11101 actatccgat tgcttttgtc ttgaccaagc atctaggaac gactcctgag ctcggtcttt
    11161 gtttgaatgc tttgatgagt caggggtgtt tagaaagcat ttgtttggag ccttttaatc
    11221 ggcaagaaag tttggcttat attaacagtc aactgggtag tcagccagtg acggaagaag
    11281 aaatggagca cctctatcaa gccagccaag gcaccccttt ctttttgtca gaatacactc
    11341 aggccctact gcgtcacgaa aaatttgtgc ctttaacgcc tgccattaag gctaagttgg
    11401 gtcttaaact agctaatcta agtagtcgtg atgacgtatt gttaaactat ttgtcttgtt
    11461 gtcggaggcc tatccctcta aataccctcg ctcaattgat gttactgcct ttagaagaag
    11521 tgatcgagat ggtggataat ctggggcact actatatttt ggtggaagaa agcgtaggag
    11581 aggaggtgtt gatttcattt cgtcagcgaa ttattcaact ctatagttat gaccgtttat
    11641 ctttgtcaaa aaggcgttta ttgcacggac aaattgccaa acggttagaa gatttactgc
    11701 ctattttgac accaagccct cacttattag atgacattgc ttaccattat caggaatcac
    11761 ggcaggtgat taaggctttg gaatacaacc ttaactatct agatgctacc ttgccatttc
    11821 agcatgagct gtttcccatt tattcaaaga gtattggctc cttggaaaag tcagatcgtg
    11881 accatcaacg cttaatgcaa gagcagtttg ataagattcg gcaaagcatt gcggatttgg
    11941 aactgaccta tgataataac cgtgatttcc agcagttgct tattcgtttt tcttaccttg
    12001 aaggccgtta tgatattcga acagggaggt atcaagaagg gattaaacac attcaaaagg
    12061 tcatcgcttt ggcaaccgag ctaaaacagc cctccttctt gctagaaggc tatcgccagt
    12121 taattcatta ctgtatccaa gtggaaaaca agccagaaat gcgttattac actagtcttt
    12181 cattggaggc agcggttgct gctaatcatt ttgaggccat tgcgattagt ttgcggttaa
    12241 acggtcttta tcatttgatt attggggagt taaatgaggc agagcgtctg cttcaacagt
    12301 cgattgactt ctttaaggtg acgtcaggct tgcaagctaa ctatgcgatt cagattgctg
    12361 ctgccttaga ttatttgggg gagatcgccc agattcgcta tcagtttgaa aaggccgttg
    12421 cttaccaaaa acaagccatt gccttgaccg aaaacaagcc agctgagtta tcagtgagta
    12481 ttttttatat tggattaggg atttcctact tttatttagc tgattttgaa caagctgagc
    12541 aaatcttgag tttggctaag gaagctttgg tcaatcatag ttatccttgg aaagaaacgc
    12601 aacttgaaat ttacctggcc atgattcaat ggaaaaaggg taattatcag ccagccttga
    12661 ctctacttga ttacagagaa accttgatgt ctaggtatcg caatccgcga gataagggct
    12721 tggttttcta tttgatggct gtggtcaagt accaattgat acgtcaagga gctaccctaa
    12781 gtcagcagga aaaggaaatg gcagaccacc tgttgtcaga atcctttgag tattattatg
    12841 agattgctag tactaacctc aacccttacc gagattgtca tttggtgagt gagttgaacg
    12901 atttgcgtca acaattatct gctaaaagct aaggaaaacc ctctgattca catcagaggg
    12961 ttttagttat gttgtgccat aatctgtacg aggtaaaaga taaaggtggc tgctaaattg
    13021 gcggtgtggt tatcaatatc gtgtggtggt gaaacctcaa ccacatcaaa gccaactaat
    13081 tttccgctag ctgcaatgtg ttgcaaaacc aagacggcaa gttttgggtc aacaccgagg
    13141 gattggatag cactaacccc aggtgcagca ccaactgaga agcagtccat gtcaatggtc
    13201 agatagactc tttcttgccc ttctaagaaa cgatcaatgg tttggcaaac cttttgatag
    13261 cccatgcgat aaatatcttg cccagtcaaa aattgaatgc ccttggattt tgccacaaag
    13321 tcaaatagga aaaggttgtt attatgttct tgaatgccta aaacgaagta tttaaagagg
    13381 cgtttgtcag caaccgcatc gtcaaacatt tgtcgaaagc ctgtccctga attagggcct
    13441 gtttggtcgt agggtcttaa atcaaagtgg gcgtccatat tgatgacagc taggtcatca
    13501 cttgaggata ggctttggcg taggcctaag tagtggccgt aggcggtttc atggccacct
    13561 cctaagacga tgggtttgag attgaggtca cacatccgtt tgatggcttt gcttaaactg
    13621 ttttgcagtt gttccaaaga gcgattgggg ccgtcaatgt tacccacatc gtaaaccata
    13681 acttggtttc ctaaatgcca agggaatttg gcgagctggg tacgtatagc agctggactt
    13741 tcgaccgctc cgacacgacc attattgata taaactccct tatcactttt aaagccaatc
    13801 aaggcaaaat gtgtcccttc aaatggggtt agtgagctgt cgttaaggtc aaggaaagtc
    13861 atgaccatgc cccatttggc agtatataag tcatcgtcga tcccaccatg ataatagcta
    13921 gtggtggatg ggtagtaatc ttctagcatg cgcgtcatct cctttaggat tatgatagca
    13981 aaataaaact tacagtcaac actttcttgg cctttgtcac tgctttttag gaatagcaga
    14041 gcaataaaat cgtctgcttt tggtcccggt tagttagtct aaagaggcca tgacctctgc
    14101 cacagcccct ctagttaaag aagtacctta ttcactaaaa ttggatactc aactcaactg
    14161 cctgctcaac cgcttcgagg aagcttgggt cttcaatgac tgctgatgcc ttgtttagtt
    14221 catcgtagat ttcgatgtgt ttatcgtgtt cgataaagtt gacttccttg cggaagagat
    14281 cgtaggcaac cttagtccct ttacctagtt catgattttc agatttgaga tcaagagctt
    14341 ggcaggctgc catgatttca gtagccacga tgcggcgaga atttttaagg atttcaaagg
    14401 ccttgcgagc agcggtggtg cccatgctga caaagtcttc ttggttctca caagatggga
    14461 tagaatccac gctggctgga tgtgccaaaa ccttgttttc agaagcaaga gaggcacagg
    14521 cgtactgggt aatcataaag cctgaattga gacctgggta tttgacaagg aaggatggca
    14581 atttgctgag ctggctattg accaaacgtt ccacgcggcg ttcagaaaca tttccaattt
    14641 cagaaatggc gatgcctaag aagtcaaatg gctgtgccat tggttctccg tggaagttac
    14701 ctcctgaaat aacgtgacca tctttacaga taattggatt atctgtgaca gaattgattt
    14761 caatgtcaac tttggatttg acataggcga tactgtcttt gctagcccca tgaatttgag
    14821 gcatgcagcg caaggtgtaa gggtcttgca cacgagattg agtagctacg gttgtgtttt
    14881 ggctgccttc aatgaggttt cggatattgc gggctgttgc caactggccg ctttgtgggc
    14941 gaatggtgtg aaggttttct tcaaatggac tagtaatccc gttatgcact tcaagggata
    15001 gggcaccagc taggtctgac agtttcaata attgaatggc gtcataggtt gcaagggcac
    15061 cgattgcagt gagaacagtt gttccgttga taagggcgag tccttcttta gcggctaaag
    15121 aaatcttgtc aataccagct ttatcaagag cttcttgacc agaaagaagc tctcctttgt
    15181 agtaagcttt ccctagacca agcataggaa gcaccatgtg agcaagcggc gccaaatctc
    15241 ctgaagcccc tagagaccct ttttcaggaa tgtaaggatg aaccccttta ttgagcagtt
    15301 ccaacagctt ttcaatggtg gatagacgaa taccagaata ccctttgacg agagagttga
    15361 tacggatcag catgatagcg cgcacggcat cttctggcaa tgggtcacca aatccactag
    15421 catgggtacg aatcaaattt tcttggagtt gaactgtatc ttctggtgag atgctcacgt
    15481 tacaaaggga tccaaaaccg gtggtcaccc cgtaaaccac ccgtttttca ctgacaatgt
    15541 catcaacaat tttacgagag gcattcacag cttcaatagc actatcatca atgcgacagg
    15601 ctatgccttg gcgagcaatc gcaatcacgt cttcgatagt aaggctttcg ccatctaaat
    15661 taatcactct tgtcatagtt tttctcctag atttgttcct tagggggcat ttggtccatt
    15721 tggtggttac gtccgtgcat aaggtagtac acactacttg caatgatgac accaactgca
    15781 ccataaacaa agttcattgg gttgtcaccc caaatcataa ctaaactaac gataactgca
    15841 agaattggga taataggacc aaatggtact cggaagatca cattagcatc gggatcgtcc
    15901 ttccgtaatt tcataacggc tagtgctgtt ggaatgtatt ggaagaagcg gaaaataaca
    15961 ctgagttttg ctaagttttc aaatgagcca gtgagtagga gtacaatagc aattgctcct
    16021 gaaaccaaga tagcaacgag tggtgcgcca ttttgatttt gcttggcaat agcagctggt
    16081 aagagccctt catcagcaat ggcagcaccg taacgtggca ccatgatgga ttctcctatg
    16141 ttaagacctg taatggaaat taaagcaccg attgagacca tccaagcgcc agcagggcct
    16201 atcattttaa caaaggcatc ttgaacaggt gcattggtca tcatgatttg agagccaagc
    16261 atggcaatgg ttccaccgat aatcagcata tataagacag agacgatact gattgatcct
    16321 aaaagagcac gcggtacatt tttttcaggg tcacgcattt ccccagcgac aatagagagg
    16381 gtttcaaaac cgataaagcc atagaagata taaacagcag tattggagat agcccctaag
    16441 aggttagtcc ctggttccaa ctgaacaaat ggggtaaagt taggaagccc gtttttgatg
    16501 aagaaaaggg tacaggcaca aaaggcaacg attggaatta acttagcaat ggtggctgtg
    16561 atggtgacaa ttttagaggt tttcaaacca gcgatattca tcaaagatag taagatgatt
    16621 aacccaatgc taagtggaat gtgccaacct tcaaaggcag ggaaagtaat gataaacatt
    16681 ctggcaaacc cagctgccat ggctgcccaa gcgaagatgg taacggtcca accaaggaag
    16741 ccaacgttaa agccaataaa atcaccaaaa gctcgtttgg aatattggaa ggctccgccg
    16801 tttttcccaa aataaccaga gacttctgca aaacaaactg ccaacatgat ggtcaaaata
    16861 gctgttccaa acataacagc gatggatgca gggccaaggc ccttgtaaat ggccctaggt
    16921 aagagaaaaa taccagagcc gataacggca ttgatcccgt aaagagtggc accgctcaag
    16981 ctaaactttg cctgttctct ttcttgttcg ttcatgtgat ttgacgccat aataatgctc
    17041 tcctttttgt ttgcaaattg cgttcaaata taatggataa ggtcgctagg aaatgaggag
    17101 atagtcggtt taggagggtc cttcttgcac ctaacgatag tgatgagcta ttggttagcg
    17161 atgagaaata ggtagccttt tgtgatgatg tgtagtgatt tcattggaga agaataggca
    17221 tgagtagtgt gatgcctatc tttatcccac taagtcttat accataagcc tgcccaaaca
    17281 gctactggag tttgggcggg gcttgtttga ttggggcaaa cttttaggtc tgaaaggctg
    17341 gcctcctgct cgattaccaa caagtgattg gcttcaagct cttgattcgc ctgattggtc
    17401 acagaataag tcagtttgct tagggcataa agcagttggc agtccgcttt gggtgcctca
    17461 aatagtgtgt cagaccagac gggtaataat tgcccttggt aatgatcatc atacattaaa
    17521 ttgatgtctt ggcaggttcc acgactgacg attctggtat cgccttcaaa cgcatagggt
    17581 tcaaaaggag ctagggaaat ctctttagca tgactcaaat cacttaatgt gatgggcttg
    17641 tctaggctca ttaggatcct gtgatagcca tcaagtcggg taaaggttgt ctgtcgtagg
    17701 gctacagttg cagttgagag acgataggag aacgttcttt ctttgtagtc tcccttttca
    17761 ggataaagga acaattggtt ggtttcaccg ccagaccagt cagtttgagt gtaatctgct
    17821 ggcgttttga ccattacggt tgtcatctgt tctctccttg tttccaatta gaatagtcct
    17881 gtgatgttgc cctcctcgtc aatatcaatt gtttcgctgg caggtacttt tggaaggcca
    17941 ggcatggtca tgatagcacc tgtcagggca acgataaatc ctgctcctgc ggacacttta
    18001 aggttgctaa tagtcactat aaagtcagtt ggtgcgccaa gttttttggc atcgtctgag
    18061 aaggaatact gggttttggc catgcaaatt gggtagttgc caaagccgag gcgttctaag
    18121 tcagccagtt cacgtttggc tgcgggggtc aaggtgatgc ctttaccacc gtaaaccttg
    18181 gtaacgattt tagtcagttt ggtttcaatg ctatcgtctg catcgtaaac aaagcggaat
    18241 tgattgtctt gctcggctag tgtcacgact ttttcagcta attcacggcc accagctccg
    18301 ccatttgccc aaacatcaga aatcacaacg tcaacgccac gtttgtcgca ggcatcatag
    18361 acagcttgta attcagcatc ggtatcaagc gggaatttat tgatcgccac gacaactgga
    18421 aggccataga cgtcttggat attagccaaa tgtttgtcaa ggttaggtaa accatccaca
    18481 acggcctgaa cattttcagt agccaggtct gcttttggca cacccccatg cattttaagg
    18541 gcacgaatag tggctactag gacaacggct gctggacgaa ggccggacat gcggcatttg
    18601 atgtcaatga atttttcagc tccaaggtca gcaccaaatc cagcttcggt aacggcataa
    18661 tcaccatatt tcaaggctag tttggtggct aggacactat tacagccatg ggcgatatta
    18721 gcaaatgggc caccgtgaat gagggctggt gtgtgttcca gggtttgcac gagattagga
    18781 tgaatcgcat ccttgagcag tgcggctagg gcaccaccag ctttcaagtc tttagctgtt
    18841 acaggttcgc cttgatagtt gtaaccgatg atgatttttt caaggcgggc tttgaggtca
    18901 gaaatatttt cggataggca caggattgcc atgatttcag aggcgacggt aatgtcgtaa
    18961 ccatcctcac gagggacccc gttgaccttg ccttgcaagc cgtcaacaat atgacgaagc
    19021 tggcggtcat tcatatccac cacacgtttc caagtaatac gtctggaatc aatgcctagg
    19081 ctattgccat ggtgaatgtg gttatcaatc aaggcagcta ataagttgtt ggcgacaccg
    19141 atggcatgaa agtcccctgt aaagtgaagg ttgatgtctt ccattgggac aacttgcgcg
    19201 tggccaccgc cagcagctcc tcccttaacc ccaaaaacag gaccaagaga aggttcacga
    19261 agggcaataa ctgctttttt tccaatggca gaaagagcat ctaccaatcc aacggaagtg
    19321 gtggttttgc cttcaccagc tggtgttggt gagatagcag tgacaagaat gagtttgcca
    19381 tcaggtttgt cttttaaggc gaccagttga cgggcatcaa tttttgcctt gtacttgcca
    19441 tagagacaga gcgcttcctc gtcaatccct aattgattgg caaccttact gataggctcc
    19501 atagtgacag agttggctat ttcaatatct gataaaacca tagttactcc tttacttgtt
    19561 aaacaatatc gagaattttc gtgtagatgt catctgccaa gtgacagccc ttgtctaata
    19621 aggcttgtcc tttttggcga tagtcggtaa caaagtcttc atctttgatg ccagacagat
    19681 taatcaaaac attcaaccaa gcgctttgta aacctgcttt taagtttaaa gcagcaactc
    19741 ctaagtcgct agcagcattt gtattagact taccgacagc tgttgcagtg atctcaagtg
    19801 cttcgaccat gagggtcatc atctcaaaag gtgattgtgc agctgttttc aaggcctttt
    19861 gcatggcagt tcgtctagca gccttgtctt cgtcagtctc ttttggcata tcaaaaacgg
    19921 cagaaaccag gttgaaggct tcggtatctt tgtcaatggc tgcaagcaag ctagcttgta
    19981 gagcggtgct tttagcatgg atctctgtaa taatagcttg gtagtcagcg tattttttct
    20041 taccaagagt caattcacag accatcttgg ttaaggaaat gccattagcg ccagagagag
    20101 cagcagcaga accaccacct ggagcagggg catctgagcc aaggacttta gcgaaatctg
    20161 ttaagcttaa atcaactaaa cccatagaga acctcctaac ctagcaaatg gttttcaaga
    20221 atctgtttat ggtagtcaaa gtcctcaact tgtaagtagt attcagccac atcgattaag
    20281 gccttggctg gcgctaagcc gatgatttca gaaccaataa cattcacacc gtagcgacgc
    20341 gcttcaaatt tgatggtttc aaaagtacgg taaagagaac atttttcaaa gttaaccatg
    20401 ttcatggaaa cttgggcaat atgacggtct tctaacatga caccgatagc cttacaatat
    20461 ttgtagccac cacctgaacc gcggataatt ttagcaattt tatgagcaat gtcgatattg
    20521 tcagtatcca aattaacatt gaaggcaacc aatggcatgc gagcaccaac ggcagttacc
    20581 ccagcagttg ggtgaatctt acgatctccg tagtcaggtg cccaatcctc ttccaacagt
    20641 ttttctggca tgccttcgaa ttgtccttta cggactttgg ccaggttttg acgttctggg
    20701 cgtgtggcag agtcttcgta aaggaagatt gggattccaa gttcacggtt aatccgttct
    20761 gcgacttgtt tggaaatctc aacacattct gctgtggtga tgtctttgat tgggacgaac
    20821 gggcagacat cggtggcacc catacgaggg tgttcgccat gatgtttggt catgtcaatg
    20881 ttttcagaag cgtatttcac cagttggaaa gctgcttctt gaatagactg gtcatctcca
    20941 actaaggtaa acacgctccg gttgtggctc gcatcagaag agtagtcgag aagggtcact
    21001 ccaggaatac ttttggtagt cgctaccaag ccgtcgataa cagcctgatt ttggccttct
    21061 gagaagttgg gaatacattc aacaattttc gccatgttta atctcctttt atgtcattga
    21121 gttactcatt aagagaatag gttacctaat ttagataacg cttacatttt tagctagcag
    21181 ttattagtga aataattgat ctaccgctga agtcacaagg tcatcatcag ccaagtatgg
    21241 gatagtgatg tgatcagtac ctgcatggag acggttgtat tcaatagcgg tttcaatagc
    21301 gtgctcattg cgagcccaat tgcgacgagc aacaccaccc atggtgtccc aagcaatggc
    21361 agatttaata atctcatcaa tgcgttcgct gccatctaaa acaagaccga aaccaccatt
    21421 gatggcttta ccaataccag ttccgccacc gttatgaaga gccactaaac tcataccacg
    21481 cgcagcgtta ccagcgtaac attgaaccgc catatcacag gtcacattgg aaccgtcttt
    21541 aatgtttgag gtttcacgaa atggtgagtc ggtaccagac acgtcatggt ggtcacgacc
    21601 aatcatgaca ggaccaatct tgcctttgcg gaccaattca ttaaatttaa gggcgatagt
    21661 cacacgaccg atacagtctt ggtaaaggat ccgggcttgg gtaccaacta cgagttgatt
    21721 tttctcagca tcacgaatcc agttgtagtt atcacggtct tgatagcggc ggtcaggatc
    21781 gatagcttcc atggcagctt tgtcagtggc caccaagtct tcgtgtttac cactcaagca
    21841 gacccaacga aaaggtccat agccatagtc aaaaagcata ggtcccatga tgtcttcaac
    21901 ataagaaggc cagataaagc cgtctttgtc gttacgacca ttcttagaaa tttctgtaat
    21961 accagagtcg taaacagact tcataaaggc attaccgtag tcaaagaaat aggtgccatt
    22021 ttcagttaac gtcttaatag cttcaaaatg ccgtgccaag gtatcatcaa ccatttggtg
    22081 gaaggtatct ttatcttctg ccaagagccg ggttctttcg tcaaagctaa tacctactgg
    22141 gcagtagcca ccgtcataaa cgttgtgaca agaggtttgg tcagacaaaa gatcaacatg
    22201 aatctgcttg tcattgacgt actctaaaag atcaacgata ttaccatggt aagcaatcga
    22261 agtggactct ttagcatcta tggctttttg ggctaattgc agagcttctt cagggctctc
    22321 agcaatttgg gtaacccagc cttgcgaatg acgggtttca atccgagatt ggtcaacttc
    22381 agcaataatg gcaactgctt tagcaatttc agcagcctta ccttgtgccc cactcatgcc
    22441 tcctaaacca gatgagataa agagtttacc ggtcaaatca ccatcgtcag ccaccccaag
    22501 tttgagacga ccagcattta agagggtatt aaatgttcca tgaacgattc cttgtgggcc
    22561 aatatacatc caaccacctg cggtcatttg accatagttg gtgacaccca tctcttcagc
    22621 gatttcccag tctttcatgt tgtcgtattc acccaccaaa aggccattag taataatcac
    22681 acgaggcgct tcaggtttgg atttgaaaag accaactgga tgaccagact caaccaccaa
    22741 ggtttgttca tcagtcatga cttctaggta ttttttaatc aaacaatatt gcatccagtt
    22801 ggcacaaaca gaaccagttt ctccataagt gactagttcg taagggtaca aggcaatctc
    22861 aaaactcaag ttattgtcaa tcatgacctg catggccttg gcagctgtac aatttccctt
    22921 gtactcgtta atgggtttgc cgtaaatgcg gtcttttgga cgccatctgt aaccatagat
    22981 gcgtcccctt gttttgagtt cttccaaaaa ttctggaatg acttcttcgt ggaacttcgt
    23041 aggtacatag cgtagggcat ttttcaaggc gatttcggtc tgagcctggg tcaatcgaaa
    23101 acctctgtct ggtgctcttc ggataccttc tttgaagaca gtcttttccg gtaaaacatc
    23161 gtctaactta acagtcatag cggcagctat gtcagtttca ctgtaaaatg acatagaaaa
    23221 ctcctcctca actccttttt attgtcgaga ttagtctaac ttagtctagt ctataaaaag
    23281 tcaaccacgc tttgaaatgc gaaaaaagtc taaaaaaaaa tcaaaacctc attttttgac
    23341 taaaatttga cgcttaatca gtacacttga ggcatgacag ataaagtcag tcagaggtta
    23401 attgttgtta ccaaagttgc aaagatcgca actattgagt gggtgagggg ggactagtaa
    23461 tggctattaa tcagttgaca aacgatgtta aaaaaggagg tttttatggt tgctgatgtc
    23521 ttattaacac attttaatca actattttgt ctaaatgatc caggtcatcc tttaactggt
    23581 caagaaatga aaaaagccac tatcgttgaa gatggctata tagccatcaa agacggcctc
    23641 attgtggctc ttggttctgg tgaaccagat gctgagcttg tcggtccaca gactattatg
    23701 cgttcttata aaggtaaaat tgcaacgcct ggtattattg actgtcatac ccatttggtc
    23761 tatggtggca gtcgtgaaca tgaatttgcc aagaaattag caggggtgtc ttacttggat
    23821 attttagctc aaggtggtgg tattttaagc acggtgaggg ccactcggtc agccagcttt
    23881 gacaaccttt atcaaaaatc caagagattg ctagactaca tgttgcttca tggagtgact
    23941 actgtcgaag cgaaaagtgg ctacggcctt gattgggaaa cagaaaaacg ccaactggat
    24001 gttgttgctg ctttagaaaa agaccatcct attgatttgg tgtctacgtt tatggcagcc
    24061 catgcgattc ctgaagaata caaagggaat cctaaggctt atctcgatgt gattatcaag
    24121 gatatgcttc ctgttgttaa agaggaaaat ctggcagaat tttgtgatat tttctgtgaa
    24181 aaaaatgttt ttacagctga tgagtcccgc tatctgttaa gcaaagccaa agaaatgggc
    24241 ttcaagcttc gtattcatgc agatgaaatt gcgtctatcg gcggagttga tgtcgcagca
    24301 gagctcagcg cagttagtgc agagcatttg atgatgataa cagatgatgg tatcgctaag
    24361 ttgattggtg ctggtgttat tggtaatttg cttccagcca ccacctttag tttaatggaa
    24421 gacacttatg cccctgctcg caaaatgatc gatgccggca tggctatcac tctctcaaca
    24481 gatagtaatc caggcagttg cccgactgct aacatgcagt ttgtgatgca attaggttgt
    24541 tttatgttac gtttaacacc gattgaagtc ttaaatgctg ttaccattaa tgcggcctac
    24601 tctgtcaatc gtcaggagag ggttggtagt ttgacagttg gtaaagaagc agatattgcc
    24661 atctttgatg ccccaaatat tgattaccca ttttatttct ttgccaccaa cttgattcac
    24721 caagtctata aaaaaggaca actcacggtt gatcgaggtc gtattcttta aaaaatttca
    24781 aaaagaagct ttgagcgtta gctcaaaact tcttttaaat atgctgtttt attgacgaat
    24841 caagtagtca aaggcaccga tggcagcagt agcaccagac cccatggaaa taatgatttg
    24901 tttataagct gaatcagtac agtccccagc agcaaagatg ccgggaatat tggttgaacc
    24961 atgtttatcc acaatgattt ctccgcggtc ggttaggttg acaccactat ctttgagcca
    25021 agctgtgttt ggaataagac caatttgaac aaagacccct tcaaggtcaa ggtgtttgtc
    25081 ttcaccgcta tcacgttcag tgtagttgag accagtaaca tgatcgtcac caacaatgtc
    25141 tttagtagca acatttttga taatagtcat gttagcagta tcagctgcgc ggtcttgaag
    25201 cactttgtca gctttgagct caggcaagaa ttctaacacg taaacgtgtt tagcaagacc
    25261 agccaagtca agggccgctt ctaaaccgga gttaccacca ccgataacag caacatcttt
    25321 gccttcaaag agtgggccat cacaatgagg acagtaagtc acccctttat tacggaattc
    25381 atcttcacca ggaacattaa tgttacgcca tttggcccca agagctaaga tagcagtttt
    25441 ggcttgtaga accgcaccat tagctagagt aacctcgatg ttttcttttt tctcaataga
    25501 agtagctagt tgtgctttga taatatcaac atcataagac ttagtatggg cctccacttc
    25561 ggccattaat tttggtcctt cagtgtaaag ggtaccaatc atgttttcga tgccgaccgt
    25621 ttccatgacc tgaccaccaa aggtttcagc aagtaaacct gtttttagtc ctttacgagc
    25681 tgcatagata gcagcgctat tgcccgcagg gccaccacca ataacaagga catcatagag
    25741 gcctttatca gcaaaggctt cctcagaaag tgggccagcg atttgttcta agagttgctc
    25801 aatggtagcg cgaccagaag tgaattcttc cccgtctaaa aagacagtag ggacagacat
    25861 aatgcctttt gctttcactt catcttggaa catgccgcct tctaccatag tgtgtgaaat
    25921 cttgtcgttc aagacggaca taatgtttaa agcttgaaca acatctgggc agttatggca
    25981 ggttaagctg acataagttt caaaatgcaa cggacggtca atggccttga tgcgatcaat
    26041 aacatcttga tccacttttg gagcacgtcc agatacttgc aagagagcaa gaataaagga
    26101 cgtcaattcg tggcctaaag gaagaccagc aaagacaacc ccactaccgt gacctttttt
    26161 cgcaacctta aagcttggtt gtcgatctaa agtgatgttt tcaatagaaa tacgctcaga
    26221 catagcagct atttcttcca caaagtcttt gactttttga gactgctcat tgtcaccaag
    26281 ggaaacttgc aaaacaagat cagcttctaa cagggtgagg tattgggcaa gttgttcttt
    26341 aatatcagga cttaatgcca tagctttcct cctaaaattt attaaatttt accaactaaa
    26401 tcaagacttg gtgtcaaagt ttcagcgcct tctttccatt tagctggaca aacttcacct
    26461 ggatgtttac ggacgtattg ggcagcgtga attttatcaa tcaaggtgct agcatcacgt
    26521 ccaataccat cagcattaat ttccatcatt tggataatac catctgggtc aacgataaat
    26581 gttccacgtt gagcaagtcc gtcttcgcca agcacttcaa aggcttgtga aataaggtgt
    26641 gaagggtcac caatcatagg gtatgtgata gtgccaacca catctgaatc atcatgccaa
    26701 gctttatgaa caaaatgagt atcagtagag acagaataaa cttctacacc aagagatttc
    26761 agtgtttcgt attgctcttg aaggtcaccg agttcagttg ggcaaacaaa tgaaaagtct
    26821 gctgggtaga aacaaaaaac tgcccatttt cctttaacgt cttcatttgt aacagtgatg
    26881 aattttccat cgtgataagc ttgagctgaa aattcagcaa tttcttttcc aattagagac
    26941 atatagttgt cctccttttt tatagtttta tacttgtatt ataaaagaac aacaagatta
    27001 tgtctactca gaaacccttg attttactgg gaaatcagcg attgttttct gacaattcag
    27061 ttgtgaaata aatcacatta attaaaatga ttctaaataa gctgaagacg ccgttaaatc
    27121 aaaggttaat ttaattataa tctacagaaa atgtaattat tattaaagcg tttacaaaaa
    27181 aacttttttg attccgttaa ggcaacttaa tattatggtt acctaatcgc taatattgta
    27241 acctattttg gcatgagatc agggaatggc tgttatatta attggatatg tcttgtgcaa
    27301 atagtgcttg acggatttgt ggaattaggg taaaataatc tttgttgtgg cggtatagcc
    27361 aagtggtaag gcacggctct gcaaaagctt gatcgtcggt tcaaatccgt ctaccgcctt
    27421 ttatatacaa aacaagcctt gattaatttc gtgaaaacgt tgttaaatca aggtttttat
    27481 tttttgcgac aggataaaaa aagagaaaaa aagaaataaa gtcggtcaaa agtcggtcaa
    27541 atttcccgaa gatgtctttt atagcctgat tattaggtat gaaaaatact atggccaaaa
    27601 ttggtaaacg attgcaaata aaggtcagag ttcttacccc cttaaacgat atgcgttaaa
    27661 agttagttga actgccgtgc acctaacgat agacacggtg atgtgagagc gagtagagtt
    27721 gaatctctac ttgtttatct taccatagtc agctttataa agtaaccacc cattacaatg
    27781 caactatatt cttaatgttt ttaagcatgt tattgacaag tgttataaaa tgtgttactc
    27841 ttagtgagta aattagtttt tgagttagta tttgtgtttc aacatcttta tttctctcta
    27901 tttttacaaa tgatttttag aaaggaagtg gatgtatatg gcacaaggta cagtaaaatg
    27961 gtttaacgct gaaaaaggtt ttggttttat ttcaactgaa aacggtcaag atgtctttgc
    28021 acatttttca gccatccaaa ctaatggttt taaaacgtta gaagaaggac aaaaagtggc
    28081 atttgacgtc gaagaaggtc aacgtggacc tcaagcagtc aatatcacta aattggccta
    28141 atctggttaa agtaactaaa gagaagcaga tgttggaaac aacaactgct tttttgattt
    28201 ctaccagtta cctttaatga ttaagagttg cgtttaaggt cttgtatttg ttataataat
    28261 agtcagtttt agtcaaaatg tattgacgtg gtgctactaa gtttttagag tagcccgcaa
    28321 gcaaaggagt gacagcatgc caaccaaaaa tacttcagac agcattgaag agtatattaa
    28381 agaattatta gctaagtcag gaatagcaga aattaagcgg tccatgctag cagattcgtt
    28441 tcaagttgtc ccaagtcaga tcaactatgt cattaaaacc cgttttacgg agagtcgagg
    28501 ctatgaagta gagagtaaac gaggtggtgg aggctatatt cgtattgcca aggttcattt
    28561 ttcagacaaa caccatctga ttggcaattt aatggcaact attgaagact gtatcagtga
    28621 gcaagttttc acggactcga tacaattgct ttttgacgaa cacttattga cagagcgtga
    28681 gggaaatatc attttggctg tggcgtctga tgatgtttta ggaactgatg gttcaactat
    28741 tcgtgcacga atgctctatc gcttattgca acgaattgac agaaagggaa gcaattaatg
    28801 attatgtatt caacgaagat gcaagacatt tttagacagg cgcagttcca agctgctcgc
    28861 tttgatagcc attgcctgga aacttggcat gttttgttag ctatggtagc tgtagataat
    28921 tctttagcaa atatgatttt aagtgaatat gatgcccaag tcgccataga agaatatgaa
    28981 gctgcagcta ttttagccat gggcaaaacc cctaaggaac agttgtctcg tgtagacttc
    29041 agacctcaat ctaaaacctt gactaacttg ttagcttttg cgcaggctat tagccaaatc
    29101 actagggatc aagaagtcgg ctctgagcat gtcttatttg ctattttatt gaatccagat
    29161 atcatggcga gtcgtttgtt agaaatagca ggctatcaga taaaagataa cggcaatggg
    29221 cagccgcgat tagctgactt gcgaaaagca atagaacgtc atgcaggtta cagtaaggaa
    29281 atgattaagg ctattcacga actacgtaag cctaaaaaaa cgaaaacaca agggaccttt
    29341 tcagatatga tgaagccacc aagtacagct ggtgaattga gtgatttcac aagagatttg
    29401 actgaaatgg caagacaagg tttgttagaa tcggtgattg gacgtgacca agaagtatct
    29461 cgtatgattc aggtactaag tcgtaaaacg aaaaacaatc ctgtcttggt aggtgatgca
    29521 ggtgttggta aaactgcgct tgcttatggc cttgctcaac ggattgcaaa tggcgctatt
    29581 ccttatgaac ttaaggagat gcgtgtccta gaattagaca tgatgagtgt ggtagcagga
    29641 acccgttttc gtggggattt tgaagagcgc atgaatcaaa tcattgatga tattgaagct
    29701 gatggtcaga ttattctttt tgttgatgaa ctacatacta ttatgggttc tggcagtggt
    29761 attgacagta cacttgatgc ggctaacatt ttaaaaccag cattatcgcg cggtactctt
    29821 catatggttg gagcaacaac tcaagaagaa tatcaaaaac atattgaaaa agatgcagct
    29881 ctttcgcgtc gttttgctaa aatattaatt gaagaaccta atacagaaga tgcttatcag
    29941 attttgatgg gcctaaaatt atcttatgag acctaccata atgtctcgat atcaaatgag
    30001 gcagttaaaa cagctgtaaa aatggcacac cgttatttaa ccagtaaaaa tctccctgat
    30061 tcagctatcg atttattaga tgaagctagt gctgctgtgc aaaacatggt gaaaaaatca
    30121 gctcctgaga ctttaacacc aatagaccaa gctcttatca atggtgatat gaaaaaagta
    30181 tctcgcctct tagctaaaga agcaaaaggt cagatgagaa aaccaacacc agtgacagaa
    30241 gatgatattt tggcaacctt gagtaagtta tcgggaattc cacttgaaaa actgacgcaa
    30301 gctgatagta aaaaatacct caatttagaa aaagaactgc ataagcgtgt gattggtcag
    30361 gatgctgctg ttacggctat ttcaagagcc attcgtcgca atcagtcagg tattcgaaca
    30421 ggaaaacgtc ctattggatc atttatgttt cttggcccaa caggagtagg taagacagaa
    30481 ctagcaaagg cccttgcaga agttctcttt gatgatgaag cagcgcttat tcgttttgat
    30541 atgtctgagt acatggaaaa attcgcagcg tctaggctta atggagcacc tcctggttat
    30601 gtcggctatg atgaaggagg tgaactgaca cagaaagtta gaaataaacc ttattcagtc
    30661 ttgctttttg atgaagtgga aaaagcacat cctgatattt ttaacgttct ccttcaagta
    30721 ttagatgatg gtatattgac tgatagtcgt gggcgtaagg tcgatttttc aaatactatt
    30781 attatcatga ccagcaatct tggcgcaaca gccctgcgtg atgataaaac ggtcggtttt
    30841 ggggtcaaag gcattcacca agaccatcaa gctatggaga aacgtatttt agaagaatta
    30901 agaaaaactt accgcccaga atttattaat cgtattgatg aaaaagtggt ctttcatagt
    30961 ctgacccaag ataacatgcg cgatgtggtt aaaatcatgg tacagcctct gattactaca
    31021 ttggcagaaa aaggtattac ccttaaaatt cagcctttgg ccttgaaaca tttgtccgag
    31081 gtcggctatg atgagcatat gggggcaaga ccattacgtc gaacgctgca aactgagata
    31141 gaagataagc tatcagagct tatcctttct cgagaattga caagtgggca tacgctaaaa
    31201 attggattat catatggcaa attaacgttt cacatagctt aatttccata taaaaggtgg
    31261 atcatccttg atgtcaccaa aaaaagaggt tattcttaca aaaataactt cttttttctt
    31321 gactattttt gaccaagtga taaaatagaa tataaagtta gcactcgatg aacatgagtg
    31381 ctaactttac taaagattct tttattggag gaaaatttca tgttaaaacc attaggtgac
    31441 cgtgtggtcg taagatttga tgatgaaaaa gagcagacag tcggtggttt tgtccttgca
    31501 ggcactcata aagagtcaac acgaaaagcg acagtcctcg ctgtcagtga aacgggtgtt
    31561 cgcactatta caggtgatag cgtgctacct tcagtttcag tgggtcaaga ggttttagtt
    31621 gaaaatgggc atgatttaga agtaaccgta gatgatgaga aagtttctat catccgtgaa
    31681 tctgacatca ttgctattgt tacaaaataa aacgacaaat ctctaaatag aaagaaggat
    31741 tgaatatggc aaaagatatt aaattttcag cagatgcgcg tgctgccatg gtgcgcggag
    31801 ttgatatgtt agcagatacc gtcaaagtaa cgcttggtcc taaagggcgt aatgttgttc
    31861 ttgaaaaagc ttttggttct cccttaatta ctaatgacgg ggtaaccatt gctaaagaga
    31921 tcgaattaga agatcatttt gaaaacatgg gagcaaaatt ggtgtctgaa gtggcttcta
    31981 aaaccaatga tattgctggt gatgggacga ctactgcaac agttttgaca caagccattg
    32041 ttcatgaagg actaaaaaat gtgacagcag gtgctaatcc aattggtatc cgtcgaggca
    32101 ttgaaacagc aacagcaaca gctgttgaag ccttgaaagc cattgctcaa cctgtatctg
    32161 gcaaggaagc tattgctcag gtcgctgcag tatcatcacg ctctgaaaaa gttggagagt
    32221 atatctcaga agctatggag cgtgtgggca acgatggtgt gattaccatc gaagaatctc
    32281 gaggtatgga aacagaactt gaagtggtcg aaggcatgca atttgaccgt ggttacctgt
    32341 ctcaatacat ggtcacagac aatgaaaaaa tggttgcaga ccttgaaaac ccatttatct
    32401 taatcacgga taaaaaagtg tcaaacatcc aagacatttt gccactactt gaggaagttc
    32461 ttaaaaccaa ccgtccatta ctcattattg cagatgatgt ggatggtgaa gcccttccaa
    32521 cccttgtctt gaacaagatt cgtggtactt tcaatgtggt tgctgtcaaa gcgccaggat
    32581 ttggtgatcg tcgtaaagct atgcttgaag acattgctat cttgacaggt ggtacagtga
    32641 ttacagagga tctaggactt gaattaaaag atgctacaat gacagccctt ggacaggctg
    32701 ctaagattac agttgataaa gatagcacag taattgttga aggttcagga agttcagaag
    32761 ctattgctaa ccgtattgca ctgattaaat cgcaattaga aacaacaact tctgactttg
    32821 accgtgaaaa actacaagaa cgtttggcga aattagctgg tggtgtagct gttatcaaag
    32881 taggagctcc aacagagaca gctttaaaag aaatgaaact tcgcattgag gatgctctaa
    32941 atgctacacg tgcagccgtt gaagaaggta tcgttgctgg tggtggaaca gcacttatta
    33001 cggttattga aaaagtagca gctcttgaac ttgagggcga tgatgctact ggacgtaaca
    33061 ttgtgcttcg tgctctagaa gagcctgtac gtcaaattgc tttaaatgct gggtacgaag
    33121 gctccgtagt tattgacaag ttgaaaaaca gccctgcagg aacaggattt aatgctgcaa
    33181 caggtgagtg ggttgatatg attaaaacag gaatcattga ccctgtcaaa gtaacacgat
    33241 cagcgcttca aaatgcagct tctgtagcta gtcttatttt gacaacagaa gcagttgttg
    33301 ctaataagcc tgaaccagct gcgccagcgc cagcaatgcc agcaggtatg gatccaggaa
    33361 tgatgggcgg cttctaaggt ctctatagca ttaaggatta tgaaaaagaa gttgagacta
    33421 aaggtctgct tcttactatg aaaaaagaac aaagattgga tttcgactca tgatatccca
    33481 tctttgtttt tttagttgtg atataaaatg ccaatctttg tggttacaga cttttaatgt
    33541 attggaaaat atattgtttt tctttgtcat gtgctatcat ggagccaatg aaaagttatt
    33601 cccatatatg cgtggtggag gtctgtgatg aatcattttg gagagatttt taaaaccttt
    33661 agagaatcaa agggattacg attaaaagat gtcgcaaagg ctggtatatc aacctctcag
    33721 ctgtcgcgtt tcgaaaaagg ggagacggat ttaaccatat cgacatttat gctgattttg
    33781 gatgaaagta acatgtccat tgatgagttt atgtatgctg tccatgattt tcatcgtgac
    33841 gacttaaatg aactcttatc aaaaagtgag ggatttcgta acaattcaag atagtgatgg
    33901 cttgaagcag ttacttcatg ctcaactagc atcaactgat aagaaggaaa tgttcacgga
    33961 tatcttttgg catatctagc atgtctaagt ctgctatggc atgccatttt gggagtccct
    34021 cacgcgactc tgtcagtagc tctccttcaa aggattcaca tagaaagtcg taatagacat
    34081 agcactcttt ttttgtcagg cttgataaag ctagaaatac cctttaattg aaggtttaaa
    34141 gctgtcagac ctatttcttc ttttagttct cataaagccg cttcaaagaa agattcacag
    34201 ggctcgactt taccttctgg ctggacccat cctggtaagt tatcgtgttg tctatggagt
    34261 cataaaatca tatcgttatg tttgacacac atattgcccc agtctctaac cgttgctatc
    34321 accagattca ccacctttta gtatagtata agaaaaaagg ggtgaaagag gtttcttgtt
    34381 gtttttttgg cttaagattt ctttaagtct tatctagtat actaatgtca ttccttaata
    34441 ggataagtat ttggttgtag aagtatcgtc ttaaactaac gctatctcaa ccgattccca
    34501 acttattcac ccctcctata ccgataaggt ctcacaaagt gtgagacctt attttttgac
    34561 ttcagctcta gttatggaga aacttgttga tacaagcttt tttgggttat gggttatggt
    34621 attatgatct attcaagcct ttcttgtttt tgggtttttc ttcaaccaac ttggcttcaa
    34681 tagcttttaa gcgtttgaag gttttttcag cgcgatctag tgaaatctta tcagcttttt
    34741 cttgagcagc tttggggtca ctgacgacta agtcactgat ttctttggtg cttttgtctt
    34801 gttcggctat ccaggttttt tccaagcctt tcatctcatc aatcacttta gttccaaatg
    34861 gttttggatg agcagccacg agatcattaa tgtgtgacac cgtccaatac catgacttat
    34921 cgttatattg ggtgcttttt tcttgatagg cttcataggt tctactgata ttgccaaggt
    34981 atggcaagta aggggcatta cgaggactgc caatagatag ccacatgaca ccaccaccca
    35041 attcagcagg gatgtctttt ttcagttgga aaatatgagc ttccatgaca ttaggatttg
    35101 agatgggata agcataacct ttaacagctt ttttggattt tggtttaccc ttaccgtcta
    35161 atgccatctg atcaagtggt ttaagatcca gcccctcaaa acgattacgt tgcagtttca
    35221 tcgcatcttc tagactgaag gtcttatcag tgctttggag caactcataa ttgctgtctt
    35281 tataagttac ttttgaatca gggtcaagtg atttaatccc tgagaaagag cgagagcggt
    35341 tggcatcgtt tagtggtgga ttgtaagatt tggcaatatg aaatttacca tcaacttcgg
    35401 tataagattt ggctttttta gcgacttttt ccacatcttc tgaggcaatc gtattttcct
    35461 tatcgttgaa atcgacatgt ccgagataga aggtatttgg aaaaacagcg tatttatcat
    35521 ctgggaattt gatggcaaca tattggtgac cagagagaat ttccatgtac cagatgccat
    35581 ctttgtcagc caaggtaaca atatttcctt cagcagctcc tttttcagtg actattttag
    35641 caatcaatgc gacaccttca cgggctgttt tgacgcttgg taaaatgaca ctggccatag
    35701 atgattccgc taagccattt ttgacgtaag gatcaatttt ttggatggca tcattagctg
    35761 aagctgatac tgttgcagac atagagacgc caaactcatt aaaaccagct tcgtcataaa
    35821 cgcctttgtt aggtgttaca tcaggaatcg cactatagcg ataagaatgc tcaggcaacg
    35881 ggtactcaaa accattagag aggtctttcc atttttcgcc agcaggattg tcctttgcta
    35941 gacgtacaat gaaattttta ttatggtgtg gctcaagatc ttctgttcga ccataaagaa
    36001 gagaaccgtc tttggttaaa tctttgccaa taataaaacc agtacaagca taactaacac
    36061 tttgaagcga aaaggctgtc agaatactta aaactccaag tgatattttt ttgtttatca
    36121 tgcgaatcct cctagtaaac gataacgctt tcacagacat tataaaatgc tctttttaaa
    36181 aattcaagtc ttttatgaag tgttttgaaa ttgttagcta tctaaatatt atgagaattc
    36241 tctcttgaat tttggcttaa cggcccctaa aaacgtatag gcagtgaact atctaggttt
    36301 cttcgaaaat ccattagcca tttatgatat aatagtaaag aaaaacatag aaagttgggg
    36361 tctgttgatg accaaaccat ttcatcataa gaaactaaaa caaataacta taatagctgc
    36421 aactagcctt tttttattcc tgatcagtgg tgccttttac tactctaaaa atcattgtat
    36481 taatgcctat cttaaagctc gatcagccca atcaggacca gtttttgaga atatcaaagc
    36541 atatctagtc tgggatgata ctaatgagca gatcacaaat gacgaggcga tgtatactaa
    36601 gtttagaagg tatagtcaaa aagaattgag gcaaaaaaag caggatttaa aagccgctag
    36661 tcaagatagt gccgttcaag taaagtctgt tggtcgtcgt ttttggattt ttcctgatta
    36721 tcggattgcc ataaaaccca tggatttaac gataaaaacg aatgtgcctc aagcagacgt
    36781 tcttttaaat caaaaaaaag ttgctgtttc tgattcagaa cagttctcag tcaagcttga
    36841 tcggctacca acggcagaat ataccgcaag tatcagaggc aaacacaacg ggcgaaacat
    36901 taaagtcaac aaatcatatg atggtgataa tcccgtgcta gatttgagtg tgtcttttag
    36961 aacttttttg gtaacaagca atgctaagca aggagatctt tacttcgatg ataaccatat
    37021 tggcacatta aaagatggtc aattacaagt agaagattac cctgttacag aaaacgcaca
    37081 agcttatatg aaaacaacat tcccagatgg tgagttaaga tcacaaaaat atgctctagc
    37141 tgatgttgaa gaaggagcaa ccctggagat tttagttaca gatcttttag aagaggacaa
    37201 ggcaggggag ctattagtat cagcttttga tcagctgatg cactacctca gtacaggtca
    37261 agactcatct aacttacgta gcgtctttga ggcagggtct agcaacgcat tttatagagg
    37321 attgaaagag tccataaaag cgaaatttca gacagataca agaaaagcca gccgtctcaa
    37381 tattccatct atccttttga caacaatgac tcaagtgggt aaaacaactt acgtgcttga
    37441 tttcacagct acctacgaat ttttgtatga caactcaaca gatcctgagc agcatacctc
    37501 tggacatatt aatcaagact tgactggaaa agtgacggta aaaaaagttg gacagcatta
    37561 ccttatcagc cagtccggct ccaaaaatat tactgttgtt aaagaggaca atcaactcaa
    37621 agcgccatct gtctttcctg agtctatttt gggaacgtgg acaggccaag ccaatggttt
    37681 gagcatccat atgtctctag catcagatgg aacaattacg actaaagttg aagatcaaaa
    37741 aggcaaccgt tctaaagaaa ctcggacagc taaaattagt aaagttgaag acaaaggcaa
    37801 tggtttttat ctttatacgc cagatcctgg aagtgacata agcgccttag ttccagaagg
    37861 aggattgggg ggtgcaaatg tcaaatatgc ttatggtttc aaaatatctg gtaaaacagc
    37921 ctctccagtg gtgtggcagg cagcattaac acatgaattt gattatacca agccactttc
    37981 gggagtaact ttgcaaaagc aaccataaag gatgcaaagc cacaaagaac agtagaaaca
    38041 atgttatcac tcaaatacag tgctatgaaa acagctaaac tcaaaaggct aggagcttat
    38101 ttcctagcct tttgagcgtt taagactgcg tcaaatgtag ctgatttagc ttgcacgcaa
    38161 atgtcttctt gggttagagg gtgtttcaaa cgtaattgat aagcatggag catcagtcga
    38221 gcacaatctt tttttccatt agaatacaaa ggatcaccaa ataaaacatg accttgatgg
    38281 gctaaatgga ctcgaatttg atgagtccgt ccagtttgta attgacaatt gagtaagctt
    38341 gccgttttgt ggaagttttt gactagagtt acctcagtaa tagctttctt gccatttatc
    38401 ggatcgacaa cacgttttct gcggtcatgt cgatgacgac caattggatg atggtaagtt
    38461 accctaggac tgtctaagga tccgtgaact agtgccaaat attctcgatg gatgtctcgt
    38521 ttttctaaaa gacgattaag gattggtaag ataaaaggtg ttttagcaaa taaaatggcc
    38581 ccacttgttt ccttatccag acgatgaacc acatagcagg tctgtcccgt gtaagcagac
    38641 acgtggttga gcagcgccaa ctctgttgga tcattgccgt gtgttttcat cccttcaggt
    38701 ttgttaacaa taatgatgtg ttcatcttca taaaggcagg ttactttttc ggcctgcccc
    38761 atcacgataa tcttttcagg ataatcttcg tgatcgaaaa aaagtttgac ctgatcaccg
    38821 tatttaacac aactttgcca gttaacagga tgaccattaa taagaacatg ttttttagtt
    38881 ctcagaaaat gcctaatttt acggggaatt aacaattgtt cctctaataa tgctttgacc
    38941 gtcaattctt caaagggatt tttcagtgtg acagtaaacc cctttgatgg tttatttgtt
    39001 gtcttcattg agccagttat ggtatttttc aacaaggttg atagccattt gggtggcaag
    39061 agcagcagag aaagcttcag taccttcacg ctcgtcatta gctacctcca agcgagtctc
    39121 atcgtaaatg gcttttagac tttctgcgga taaggtttct ttaaaagctt ggaatttatt
    39181 cattggttaa acccgtcctt ctatgtttaa tgtgagctcc tgattaatgc aaggaattca
    39241 atgctattat agcatgtttc taatcaaaac gtgccactca aaaaggtaaa aacgttattt
    39301 tgctaatcca tataataaga aagtgtctta aataagacct cttgatagag tttgtaacag
    39361 aaatgatatg aaactaggtg ctaacgcaga aatagaaaac aactaacgtg ttgcgaagtt
    39421 ggaacagtca taaaaaatag caagataaaa cttatcaaca cacagttacc taagacgatg
    39481 agtcaaacag gtatgttctt tcaaaacaac cccatgaggt tgaacgacgt atcggaaaaa
    39541 tacggattag tttggcctta tgataggtcc ttctctatcg taaaagaagt caaccaaagg
    39601 tttttaatat aaaatattaa gaaaaattgt tataattatg ataaaaacat aatcgtaaaa
    39661 tagaggaaaa acaatgaaaa caattagacg ttatgatgtt aacgaagata gagggcatac
    39721 aggccttgta gaagcaggag atttctatta tttaaactat tgtgtcggca atgtcggaca
    39781 agacattgaa agtcagatta atggagcctt tgacgagatg gagcgccgat tagcattggt
    39841 ggggctcaca ttagatgcag ttgttcaaat ggattgtcta tttcgagacg tttggaacat
    39901 acctgtgatg gaaaaaatga ttaaagagcg ctttaatggc agatatcctg ctcgaaaatc
    39961 gattcaaacg gaatttgcac atcacggtgg accacaagga ctactctttc aagtggatgg
    40021 tgtggcttat tcaaaacata tttcgatgac ctaatcaagg ttactttaag atcatagtgg
    40081 tataataacg ttatgagatt tctagaactt ttacaaaaga aattttttcc taaagcatat
    40141 caggaaaaac aattcttaat gcatcaaaaa gcgcgtttaa cgccacaaca caatcaaaag
    40201 cagtattcgc caaatgccaa tcatttggac tcatcagcta ccaaaaactc agaacaagac
    40261 cctgcaatag ctctgcaacg cagtagagcc tatgaaggaa gccctaaaag tcggcccgct
    40321 tggttgcaaa agttggaagc tgttttgccg tctcctcaac atccaattcg gcgtttttgg
    40381 cgccgctatc acatcggaaa actgctaatg attctgattg gaactcttgt cttactctta
    40441 ggatcatact tgttttactt atcaaaaaca gctaaagtat ctgatttaca agatgccttg
    40501 aaggctacaa ctgttattta tgatcacaaa ggagagtatg caggcagttt atctggtcaa
    40561 aaagggagtt atgttgagct caacgctatt tcagatgatc ttgagaatgc tgttattgcc
    40621 actgaggata ggacttttta cagtaatagc ggtattaatc ttaaacgctt cttattggcg
    40681 gtagttacgg cgggccgctt tggaggtggc tcaacgatta cacagcaact ggctaaaaat
    40741 gcttatctct cacaagatca gacaattaaa cgaaaggccc gagagttttt tttggcgtta
    40801 gagttgacca aaaaatacag taaaaaagat attcttacta tgtaccttaa caactcctac
    40861 tttggaaatg gagtttgggg agttgaagat gccagtcaaa aatattttgg aaccacagct
    40921 gctaacttaa cactggatga agctgccaca ttagcaggta tgctcaaagg acctgaaata
    40981 tataaccctt accattctct aaaaaatgct actcaccgta gagatactgt tttaggagcg
    41041 atggttgatg ccaaaaagat tacccaaaca aaagctcagc aagctagagc agtagggcta
    41101 aaaaatcgct tagctgatac ttatgttggt aagacagatg actacaaata cccatcctac
    41161 tttgatgctg ttattagtga agcaatagca acttatggtc tttcagaaaa agacattgtt
    41221 aataatggat acaaagttta caccgagcta gatcaaaatt accaaactgg catgcagacg
    41281 acttttaaca acgatgaact gtttcctgtt tcagcttatg acggtagctc tgctcaagca
    41341 gctagtgttg ctttagatcc taaaacagga ggtgttagag gtctgattgg tcgtgtgaat
    41401 agtagtgaaa atccgacttt cagaagtttt aactatgcga ctcaagcaaa acgtagtccc
    41461 gcatcaacaa tcaaaccact cgtggtttac gcgccagccg ttgcttcagg atggtcaatt
    41521 gaaaaagaac taccaaatac cgttcaagat tttgatggct atcagccaca taattatgga
    41581 aattatgaat cagaagatgt tcctatgtat caagcattag caaactctta taatattcca
    41641 gcagtttcta cattgaacga tatcggaatc gataaagcct ttacctatgg taaaacattt
    41701 gggttagata tgagctctgc caaaaaagag ttgggggtag ctttaggtgg cagcgtgaca
    41761 accaatccat tggagatggc tcaggcatat gctgcctttg ccaataatgg agtaatccat
    41821 cctgcgcact tgattaaccg gattgaaaat gccaggggtg aagtgctcaa aacctttact
    41881 gataaggcta aacgtgttgt cagccagtct gttgcagata agatgacagc catgatgcta
    41941 ggtacctttt caaatggaac agcagtcaat gctaacgtat atggctatac actagctggt
    42001 aaaacaggga cgacagaaac caacttcaat cccgacttag caggcgatca gtgggttatt
    42061 ggttatacgc cagatgttgt tattagtcaa tgggtaggat ttaatcagac cgatgaaaat
    42121 cattatctaa cggattcaag tgcaggcacg gcttcagcta tttttagcac tcaggcatct
    42181 tacattttgc cttataccaa gggcagccaa tttcatgtag ataatgccta cgctcaaaat
    42241 ggtatttcag ctgtttatgg agtcaatgaa acaggtaatc aatcaggagt tgacactcaa
    42301 tctattattg atggtttaag aaaatcagca caagaagctt cgcaatcact atcaaaagca
    42361 gtcgatcagt cagggttacg tgataaagcc caatctattt ggaaagagat tgttgactat
    42421 tttagatagc ttgcagtatt ttagagatcg tgttaaaata atagttacgg aggcgttatg
    42481 gcacagaaaa aagcgagtct agcgtgtgtc gaatgtggca gtcgtaacta ctctatcgga
    42541 gtgagtagca cgcctaaacc aacacgtcta gaagtaaata aattttgcaa atactgcaaa
    42601 acatatacct tacacaaaga aacacgttaa aaaggagagc ctgatgggat tcattagcgg
    42661 gacttttaaa gtcttaaaag acacaacatg gccaaatcgt aaacaacgtt ggaaagattt
    42721 tatctcagtt cttgagtaca cagctttctt tacggtgatt atctacatct ttgaccagct
    42781 cttagcaaag agtgtattag cactgattaa tttattttag gtcaagattg gtagaaatga
    42841 taagcttgct tggaaaagcc taggctggga gtattcccag ccttttttgt agtatcaata
    42901 atctaattag taagcttttt aaagcccata ctggtttgag ctattcaaaa gcataaaggt
    42961 aaaggcaatg tagcaacgat ctccaaacca agttcactaa attagcttgt aacagagtca
    43021 acgcataaac agcctggcct cacttgctta gcacattaaa aatagcaatg aatattatgg
    43081 ttgaggaaaa cagcctgata gtctgctaaa tcttcgggat gataagcctt gacctcagcc
    43141 atctcatact ccctacctag aagtttgtac ttgttttctc caaattgatg gaaaggtaac
    43201 agttgcactt ggtcaatctc aagctgatta aagagctctg agaaggcttt agcatcgtct
    43261 agtgaatcat taaattgggg aataacaggg atgcgcaaga cgatttcttt tccagcttga
    43321 aaggcataat gaatattttt gataatcaag tcattacgaa ccccagtcac tttttggtgt
    43381 ctgagctgat tataatgttt caaatcggta tagataaagt ctacgtagtc aataagggtg
    43441 acaaattgct cgtgtttggc aaaggcggtg gtttcaattg cggtgtgaag acctgctgct
    43501 ttggctgctt ttaacagggc taaggcaaag tcaaattggg caaagatttc cccccctgac
    43561 agggtcatgc ccccacctga ctcttcgtag aaatcaaggt ctttaaggac ttcttcgatc
    43621 acctcgtcca cggttttttc ctctccaact attttagtat taagcccatc acttgttaac
    43681 atctgctcag gtgctttttg ttgggattcg ggattggcac accaaggaca tctcaaggga
    43741 caacctttta aaaaaacggt tgtccgaata ccagggccgt catgaatact aaaatgttgg
    43801 atgttgaaaa caataccgcg atcagtcata agtgtgaatt cctttcgttg taaaaccatc
    43861 ataccagata aacgtaaata aatcaattac gaatgaaagt aaatatccct tttcttttaa
    43921 gaaaataact ggtacaatga aagggaggtg aatgatgaat cgattagaac gtattattca
    43981 actggtttcc cagaagaaaa aaatagatgt taacagttta tcagagcaat tagaagtttc
    44041 gaaagtaacc attcgaaaag accttgataa gcttgaaagt aagggcttgt tgcgacggga
    44101 acatggctat gcggtgctaa acagtggcga tgacctcaat gtacgcttgt cctacaatta
    44161 caacataaag cgacggattg cagaaaaagc agctgaattg gtgcaagaca acgataccat
    44221 tatgattgaa tctggctcaa cctgtgccct tttggcagaa gtgctttgcc agaccaaacg
    44281 aaatattaaa gtcattacca attcgtgctt cattgccaac tacattcgtc aatatagtag
    44341 ctgtcaaatc attttactgg gcggttatta ccagcccaat tcagaggtga ctgttggtcc
    44401 tttattgaaa gaaatgatat ccctttttca tgtcaatcgt gtctttgttg gaacagacgg
    44461 tttcaacaaa gatcttggct ttatgggcaa ggacatgatg cgctcagaag gggtgcgtta
    44521 catggcagat gctgctgagg aagtggtgat tctgaccgat tccagcaagt tttcaaaaac
    44581 cagtctggta caccagttgt cattagctga tgtcaatcgc gtcattacag accaagcact
    44641 agacaagcaa acacaagagt tattaagtgc tagtggtctt gttcttgatt ttgtttctta
    44701 gaaaataggt ggctagatga aagaagaacg cagacggctc cttgccaagg tggcttactt
    44761 gcattatgtt caaggcaaga gccaaacctt gatttcaaag gaaatgaata tctaccgaac
    44821 aacggtttgt cggatgttag caaaagccaa ggaagaaggc attgttcgga ttgaaattgc
    44881 cgactatgat gctgatttat ttgctttaga agaatacgtg cgaaagcagt atggcttgga
    44941 aaaactagac cttgtgccca accaggttga agatacccca atggatacct tgacaaatgt
    45001 tgctaaaaca gcagctgagg tttttagaca tgttgttaaa gatggcgata agatcggtct
    45061 gtcctgggga gcgactcttt cttgcttgat ggatgagtta aatccaaaag cgatgaaaga
    45121 tgtgtttatt tatcctttgg caggaggacc tagccatatt aatgccaaat accatgtcaa
    45181 taccctggtt taccgcttgg ctcgcatctt tcatggtaat agcgctttta tgaacgctat
    45241 ggtcattcaa gaagacaaac acttggctaa gggaatctta caatctaaat actttaacga
    45301 cattttaaca agctgggacc agctagatct tgccttagta ggaattggtg gggagcctaa
    45361 tagccttgag cagagtcaat ggcgtgattt attaaccagc tcagaccatg accaactcaa
    45421 atatgaaaaa gccgttggtg aagtttgttg ccgtttcttt gatcaggcag gtcagccagt
    45481 ttacactggc ctacaggatc gaactattgg tatttcgcta gaacagttga ggcgtgtccc
    45541 caaaacaatg gctgttgcaa caggtaaaca caaggctaag gcaatattgg cagccttaaa
    45601 agcaggtttt atcaattatc tagtgacgga taaagaaacc atgctagctg ttttagcgtt
    45661 agatgaagat attgatctta ataacgttct tctttaatag aaattcaaag atactatgat
    45721 atttatagag gcccaagacc aaacggtcag ggcttttttt gtttgatgtg ctgataaaac
    45781 agagattgct caaatgtgca gttaatgtat tggcacaaaa gtgcattaac caaaatatag
    45841 cacaaaatat attgacccta aaaacaaaaa tgatacaata aacttaccaa cgaaatgtaa
    45901 acgattacaa acataataac atcaccttcg aaaaaaagac tcattgccgt tacatcacat
    45961 gaaaaagaaa aaaaggagac accaatgcaa gttattgtac cagaccaaat cattatgggc
    46021 ttaattttaa atgcaggcga tgccaaacaa catatctacc aagctctgaa atgtgctaaa
    46081 gaggacgatt atgccactag tgaaaaagaa atggccttag cagatgatgc cttattagaa
    46141 gcccacaatt tacagaccca gtttcttgcc caagaagcta gtggtaataa gtcagagatt
    46201 acagctcttt ttgttcactc acaggatcac ttgatgacga ccattacaga aattaatctc
    46261 atcaaagaga ttattgacct tcgtaaagaa ttggcaacta aataagtttt catgactaaa
    46321 aaggagattg acatgattaa aattggattg ttttgtgcag caggattttc aaccggtatg
    46381 ttggtgaaca acatgaaagt agctgctgaa aaaaaaggca ttgattgtca gattgaagcc
    46441 tatgctcaag ggaaattagc ggactatgca ccattacttg atgtggcact tttaggccca
    46501 caggttgcct atactctgga taaatcagaa gctatttgta aagacaatga tatccctatt
    46561 gcagttatcc aaatggctga ttatggaatg ttagacggca acaaggtgct tgatttagcc
    46621 cttagccttg ttaaagaata ggagtcaatc atggcaaaaa tgaatatgca aaacatcatc
    46681 aagccaatca tgacatttgt gaatatgcgc ggcatcattg ccttaaaaga cggtatgtta
    46741 gccattttac ctttgaccgt tgtggggagt cttttcctga ttgctgggca gattcctttc
    46801 caaggggtta atgatgccat tgctagtgtg tttggtgctg actggacaga accctttatg
    46861 caggtttacc atggaacatt tgctattatg gggttgattt cctgttttgc aattggctat
    46921 tcttatgcta aaaactcaga tgttgaacct ctcccttcag gggttctatc cttgtcagcc
    46981 ttctttattt tattgagatc atcttatgtt ccagcagaag gtgaagctat tggagatgct
    47041 atcagtaagg tttggtttgg tggtcaaggg cttattggtg ctattgtgat tggtttaacg
    47101 gtcggagctg tttacacaac atttatccgt cgtcatatcg tcattaaaat gccagatcaa
    47161 gtgccacaag ccatcgccaa acagtttgaa gccatgattc cagcctttgt gatctttacc
    47221 ttgtcaatgc ttgtgtatat tattgccaag tcagtaacag gtggtggcac ctttattgaa
    47281 atgatttatg atgtcattca ggtaccgctg caagggttaa cgggttctct ttatggcgca
    47341 ctaggtattg ccttctttat ttcctttctt tggtggtttg gcgtgcatgg gcaatctgtg
    47401 gtcaatggaa ttgtcactgc tcttctctta tcaaatctag atgccaataa ggccttgatg
    47461 gcagcaggtg agttatccct agacaagggt gcccatattg taacccaaca atttttagac
    47521 tctttcttga ttctatcagg ttctggcatt acctttggtt tagtggtagc tatgatcttt
    47581 gcggctaaat ctaaacaata taaggcctta ggtaaggttg cagccttccc agccctcttt
    47641 aatgttaatg aaccagttgt ctttggtttt ccaattgtaa tgaatccagt catgttcttg
    47701 ccatttatct tggttcctgt cttggcagct ctcacagttt atggcgccat tgctattggt
    47761 ttcatgcagc cctttgcagg agtgaccctt ccgtggtcaa caccagccat tatctcaggg
    47821 ttcatggttg gtggctggca aggagctatt gtgcaaattc ttatactcat catgtcaacg
    47881 ttggtgtact tcccattctt taaaatccaa gataatatgg cttatcaaaa tgaacaagct
    47941 actgaagagt catgatttag cgtccacaca aattcttgag accatctcca gttagaggtg
    48001 gttttttaga aaaagaagag cgatttatca ggcctatatt gcacaatagt gcaaaataaa
    48061 gtgactatct cttcttatgg ttaaggatac gcaaaagtcg caatatatga taaaatagtt
    48121 acgaaagaaa catttataat ttcgtaagaa agaaggagac cccgcatgac tgaaacaaaa
    48181 agcccttatt ttggacattt aacagacaga atggctcact atcgtgaagc tgtgttagac
    48241 aagaaacctt atattgatgc tgagcgtgct attttagcca ctgaagccta tcaaaaacac
    48301 caaaataagc cagcaaacct caaacgcgct tacatgcttc aaactatttt ggaaaacatg
    48361 accatctata ttgaggatga aagcctcatt gctggtaacc aagcctcttc aaacaaggat
    48421 gcaccgattt tcccagaata cactctggaa tttgtcctca acgaacttga tctttttgaa
    48481 aaacgagatg gggatgtttt ctacattacc gaagaaacca agcaacagct ccgagacatt
    48541 gccccattct gggaaaacaa taacttgcgt gctcgctgcg gtgtcttgct accagaagaa
    48601 gtgcaagtgt acatggaaac aggtttcttt ggcatggaag gcaagatgaa ctctggggat
    48661 gcccatttag cggttaatta ccaaaaactc ttggaacacg gcttgaaggg atttgaagaa
    48721 cgggcacgag ctgccaaagc tgcgcttgat ctgaccattc ctgaaaacat tgacaaatac
    48781 catttttacg actctgtttt tattgtcatt gatgcagtca aaacttatgc caaacgctat
    48841 gccaagttgg ctagagaatt agcaaaaacg gctaaaccag aacgtcaagc agaattgtta
    48901 gacatcgcgc gcatttgtga caaagtgcct tacgaaccag cgaaaacctt tgcagaagct
    48961 gtgcaatctg tctggttcat tcagtgtatt ttgcaaattg aatcaaacgg gcattcccta
    49021 tcttatggcc gctttgacca gtacatgtat ccttatgtca aagctgattt ggaggctggc
    49081 cgtgaaacag aagacacaat cgttgagcgt ttgaccaacc tctggattaa gaccttgacc
    49141 attaataaag tacggagcca agcccacacc ttctcatcag caggtagtcc actttaccaa
    49201 aacgtgacga tcggcggtca aacacgcgat aaaaaagacg cggtcaaccc attgtcttac
    49261 cttgtcctac ggagtgtggc tcaaaccaaa ttgccacaac ctaacttgac tgttcgttac
    49321 cataaaggcc tagacaatac ctttatgaac gaatgtattg aggtcatgaa acttggtttt
    49381 ggtatgccag ccatgaacaa cgatgaaatc atcattccat ctttcatcaa aaaaggtgtc
    49441 tcagaagaag atgcttatga ttactcagcc attggctgtg tggaaacagc agttcctgga
    49501 aaatggggct accgttgcac ggggatgagt tacatcaact tccctaaaat tttgctgatt
    49561 accatgaatg acgggattga cccagcatca ggcaagcgct ttgcaaaagg acacggtcac
    49621 ttcaaagaaa tgacctctta tgaagaatta aaagcagcat gggatgccac cctgcgcgaa
    49681 attacccgca tgagcgtcat tgttgaaaat gctattgacc tcggtcttga acgtgaagta
    49741 ccagatattc tttgctcagc cttgacagat gattgtatcg gtcgtggcaa gaccttaaaa
    49801 gaaggcggag ctgtttacga ctatatctca ggccttcaag tcggtattgc caacctatca
    49861 gactccctag cagcgctgaa aaaattagtg tttgaagaag gtcaattaac tccagaagaa
    49921 ctctggcacg cccttgaaag tgactttgct ggagaacgcg gagaagacat ccgccaaatg
    49981 ctcatcaatg acgcaccaaa atatggtaat gatgatgact acgcagatag tttagtcgtc
    50041 gaagcttacg acacctacat tgatgaaatt gccaaatacc caaatacccg gtatggccgt
    50101 ggcccaatcg gaggtatccg ctattctggg acatcatcaa tctcagccaa tgtcggacaa
    50161 ggaaaaggga ccttggcgac accagacggt cgccatgcag ggacacccct agcagaaggc
    50221 tgttcaccag aacacagcat ggacaaaaaa ggccctactt cagtattgaa atctgttgct
    50281 aaattaccaa cagatgagat tgtcggagga gtactactca accaaaaagt taacccacaa
    50341 accctggcca aagaagaaga caaactgaaa ttaatggcct tacttcgtac cttctttaat
    50401 cgcctacacg gttatcatat ccagtacaat gtcgtgtcac gtgaaacctt gattgatgcc
    50461 caaaaacatc ctgaaaagca ccgcgacctc attgtccgtg ttgccggcta ctcagctttc
    50521 ttcaatgtgc tctcaaaagc aacccaagat gacattattg aacgtacaga acacacactt
    50581 taggagaaaa taagtatgga atacatgtta gacactttag atttagaagc gattaaaaaa
    50641 tggcatcaca ttttgccgct cgcaggtgtg acctcaaacc cttctattgc caaaaaagaa
    50701 ggtgacattg atttctttga acggattcga gaagtccgtg ctattatcgg tgacaaggct
    50761 tctattcatg ttcaagtgat cgcccaagat tacaaaggca ttttaaaaga tgctgctgaa
    50821 atccgcaggc aatgtggaga tagtgtgtat gtcaaagtac ctgtaaccac agagggcctt
    50881 gcagccatta aaaccttgaa agccgaaggc tatcatatca cagcaaccgc tatttatacg
    50941 accttccaag gactattagc cattgaagct ggcgctgatt atttggctcc ttactataac
    51001 cgtatggaaa atcttaatat tgatccagaa gctgtcatag gacaattagc agaagctatt
    51061 aaccgcgaga atgctgatag taagattttg gcagcaagct ttaaaaatgt ggctcaggtc
    51121 aataaatcct ttgctctggg agcacaagcc atcactgctg gcccagatgt gtttgaagca
    51181 ggatttgcca tgccatctat tcaaaaagcg gttgacgatt ttggcaagga ttgggaagcc
    51241 attcatcacc gcaagagcat ttaagaaata gcatcagtag taatcacatc attaggaatc
    51301 acagataaag gagttcaacg atgaaagtat ttgcaagtcc atctcgttac attcaaggta
    51361 aaaatgcctt gtttaccaat gctaaaaccc taaaacaact aggggatagt cccattttac
    51421 tgtgtgatga cgtggtgtat ggcatcgtcg gagaaagatt tgaaagctat ttgatagata
    51481 atagcatgac tcctgttcac gtagccttta atggcgaagc ctcagataat gaaatcagtc
    51541 gcgtggttgc cattgccaag gaaaatggca atgatgttat tattggtctt ggtggtggaa
    51601 aaaccattga cagtgctaag gctatcgctg atttacttgc tgttccggtg attattgccc
    51661 caaccattgc ttcaacagat gccccaacct cagccttatc ggttatttac accgatgaag
    51721 gagcctttga aaaatacatt ttctattcaa aaaatccaga tcttgttttg gttgacacac
    51781 aagtgatctg tcaggcacca aaacgcttat tggcgtcagg gattgcagat gggttagcaa
    51841 catgggtaga ggcgcgtgct gttatgcaaa aaaatggaga caccatggca ggtggcaatc
    51901 aaaccttggc aggagttgcc attgccaaag cctgtgagca gaccttgttt gcagatggcc
    51961 taaaagcgat ggctagctgt gacagacaag tcgtgacccc ggccttggaa aatgtcattg
    52021 aagccaatac acttcttagt gggcttggtt ttgaaagtgc gggtctggct gctgcacatg
    52081 ccattcacaa tggctttaca gcgctgacag gtgctattca tcaccttacc catggtgaaa
    52141 aagtcgccta tggcacgttg acccaactct tcttggaaaa tcgttcgcgt gaagaaattg
    52201 accgctacat cgacttttac caagctattg gcatgccaac aaccctcaaa gaaatgcatt
    52261 tagacacggc tactcaagag gatttcttaa aaattggccg tcaagcaacc atggcaggcg
    52321 aaaccatcca tcaaatgcca tttgttatca gtccagaaga tgtagcagcg gctttggttg
    52381 ctgttgatgc ctatgttacg agtcgatagg ctaaccaaaa agagatttct tatttgccag
    52441 ataacctcaa aaaaacaagt ctagggagtc acttcctaga cttgttttgc ttattgttgg
    52501 ttggtaatag cacttttagc ggggtcattg tgggcaatac ggctggcagc tgctgccgca
    52561 atggcgctaa caatatcatc taaaaaggta tggcaggagt agccatcttt gtggttgagt
    52621 ttgtcaacaa ttcctggttt tgtcttgtcc agatacccat aattggtaaa accgatagac
    52681 ccatagaggt taacaatgga taaggccagg atttcatcaa tcccatacag cccttggtcg
    52741 gttttcaaga tactaaggag tggctcagac agctggttgg cttcagccaa tttatccaat
    52801 tctaccccag tgataatagc attttgcact tctcgttttg caagcaccgc ctcaacgctc
    52861 tctaaacatt ctgccatggt caaattggga atataatcat tctgcaaaaa aagcaccagc
    52921 tctgcaatag cttctaaaga accccctcgc tcagccagta attgataaga cacttctcgt
    52981 aggtgatggt cagttgacat gtgagacctc ctttttttct ttattgtaac ataaaagatt
    53041 tcgagaaacc tctacaacag ctaaagaggg gatagttctt ttttaagaga tgttgactac
    53101 tgagatcccc tacttggtaa aagtcaaaga aacgatagta aagtaaccat cttacctagg
    53161 cctaaataca atcaccaccc ctaggtgaca cacagcacta tttcaaaaat gatattagta
    53221 tggcaaaaca aaaagacaac gccttctttt ttctccttac tatctccttt aattttcata
    53281 ttttttaaaa aaactattga taaactagtt aagtaagcgt atactatggt tagtgagcga
    53341 aattagaaaa gaggacaagc atatgaatct acttggatca agacgggttt tttctaaaaa
    53401 atgtcggcta gtaaaatttt caatggtagc tcttgtatca gccacaatgg ctgtaacaac
    53461 agtcacactt gaaaatactg cactggcacg acaaacacag gtctcaaatg atgttgttct
    53521 aaatgatggc gcaagcaagt acctaaacga agcattagct tggacattca atgacagtcc
    53581 caactattac aaaaccttag gtactagtca gatcactcca gcactctttc ctaaagcagg
    53641 agatattctc tatagcaaat tagatgagtt aggaaggacg cgtactgcta gaggtacatt
    53701 gacttatgcc aatgttgaag gtagctacgg tgttagacaa tctttcggta aaaatcaaaa
    53761 ccccgcaggc tggactggaa accctaatca tgtcaaatat aaaattgaat ggttaaatgg
    53821 tctatcttat gtcggagatt tctggaatag aagtcatctc attgcagata gtctcggtgg
    53881 agatgcactc agagtcaatg ccgttacagg aacacgtacc caaaatgtag gaggtcgtga
    53941 ccaaaaaggc ggcatgcgct ataccgaaca aagagctcaa gaatggttag aagcaaatcg
    54001 tgatggctat ctttattatg aagccgctcc aatctacaac gcagacgagt tgattccaag
    54061 agctgtcgtg gtatcaatgc aatcttctga taataccatc aacgagaaag tattagttta
    54121 caacacagct aatggctaca ccattaacta ccataacggt acacctactc agaaataata
    54181 ccaaaaggct agacctctgc tcactaggcc tagcttttta catcaaaaaa agcaatgact
    54241 atagaaagta aaaatactag aaaaagcaat gattgccgtc attgcttttt atgatttgtc
    54301 aaaaagtaaa aagcaaattg aaaaaatcgc cctggagctg ttgagataaa ctacaccatt
    54361 tattaagata ccaaatcaaa aagctaacac cataagagcg ttagcttttt aaagagcctc
    54421 aggacagttt atgtttaatg gcttctaggt aggtttgaaa catatgatgg atcgttttgc
    54481 aattaagtaa ttggaagatc tccaagatct gcacacactt ttgctcagcc ccctctttac
    54541 catttatgag accaataatg ccatcaaaaa aagacacaca acaccgttca tataagcaat
    54601 catcatttag ctgataatct tcaatttttg ccaaaatctc agaagcttta tcatactctt
    54661 gtcgctgaat aaacaaaatc aacatattga caaacatccg aatcgattca ttcccataat
    54721 accttagggt attgtattta tcgaggttca aaataacttt tgaaaacacc atctcaataa
    54781 agcaagactc aaaaataaac atacaattat taaaaagcac agtctcatag tgactccaag
    54841 tttcaatatt aataagatag tttgacaaat aagtccgctc tgtcagacag tcttcctcag
    54901 taagagttgc taataacacc ttgaccaagg caaaaaggtt cttttccttt gttgacttac
    54961 tatctttata agaatcaagg atatgattta aaccttctat gtttcggcat tcaaaataat
    55021 gttttgccgt atccatatca ataaattctt tgtattgttt aaagttatta ctaataaaga
    55081 gaaactcatc aacattgaca ttcaagttgt ctaagatata aagtaacttt ttcgaagaaa
    55141 tgtcaagatt atttttaata aaacgataat aggtttgcct agtgagataa tcaccacaaa
    55201 cttgtttaat cgaaatgttt tttgaatgcc taatgaattc aacggtttca ccaatttcca
    55261 tatgtcaagc cttcctagtt gatgtcaaaa atacgttacg catgtaccta atacgtaaca
    55321 agttgaatgt ttcggatgat agtcgcttat gataggtgca taaggtcaat aaccagatgc
    55381 gatagtttta tcaactgtca tatgttaaac ctttctaatc taatagatgt taaaaatacg
    55441 ttacgtgtgt acctaatacg taacaaaata atgggttagc aaaataagca gctatgatat
    55501 agccataagg ttaaaaggag gcgcctacta tgtggttatt gttactattt ttgtagttcc
    55561 ttttgcaaaa tggtagtaga taaaaatgag aagtcaataa aagcattgac aaacaaaaga
    55621 atcattttgt ttatattatc agtattttta agtttcttgt caactgaaat gagcatctac
    55681 tagccacaat agtaactaaa aggctaattg tcagtaaaaa tgagataaat cagccaggaa
    55741 aaagcctacg agtcaactaa tggacaaccc aaaaaaagac aaaggacttt cacttggtgt
    55801 tgtggaccct atcacgatcc ttatcacaga atcagttatt aacaaaatga gaacggtccc
    55861 atatcatcta aaaaaactgt caagcacaac ctattgtttg ctagctgatc ttgcctatca
    55921 gtctgcctag cagatacggc agaagataag aaatcaacca aaagatgata agtgcaacga
    55981 ctcatagcgt cttttgacca aaaccaatta ggctcacatg agatgagaat aattgggttg
    56041 ggttgtcagt gtcaactaac cgtgttattg tctattacca ttcatggtat cagcgacatc
    56101 gtatgataat catacgattc agctaagtaa ggaggtgtgt ccaatgtacc gttaaaagca
    56161 aatgcagtag attaacttat tttgaaagag gtataaaaaa aatgaataaa aagaaattag
    56221 gtatcagatt attaagtctt ttagcattag gtggatttgt tcttgctaac ccagtatttg
    56281 ccgatcaaaa ctttgctcgt aacgaaaaag aagcaaaaga tagcgctatc acatttatcc
    56341 aaaaatcagc agctatcaaa gcaggtgcac gaagcgcaga agatattaag cttgacaaag
    56401 ttaacttagg tggagaactt tctggctcta atatgtatgt ttacaatatt tctactggag
    56461 gatttgttat cgtttcagga gataaacgtt ctccagaaat tctaggatac tctaccagcg
    56521 gatcatttga cgttaacggt aaagaaaaca ttgcttcctt catggaaagt tatgtcgaac
    56581 aaatcaaaga aaacaaaaaa ttagacacta cttatgctgg taccgctgag attaaacaac
    56641 cagttgttaa atctctcctt gattcaaaag gcattcatta caaccaaggt aacccttaca
    56701 acctattgac acctgttatt gaaaaagtaa aaccaggtga acaatctttt gtaggtcaac
    56761 atgcagctac aggatgtgtt gctactgcaa ctgctcaaat tatgaaatat cataattacc
    56821 ctaataaagg gttgaaagac tacacttaca cactaagctc aaataaccca tatttcaacc
    56881 atcctaagaa cttgtttgca gctatctcta ctagacaata caactggaac aacatcttac
    56941 ctacttatag cggaagagaa tctaacgttc aaaaaatggc gatttcagaa ttgatggctg
    57001 atgttggtat ttcagtagac atggattatg gtccatctag tggttctgca ggtagctctc
    57061 gtgttcaaag agccttgaaa gaaaactttg gctacaacca atctgttcac caaatcaacc
    57121 gtggcgactt tagcaaacaa gattgggaag cacaaattga caaagaatta tctcaaaacc
    57181 aaccagtata ctaccaaggt gtcggtaaag taggcggaca tgcctttgtt atcgatggtg
    57241 ctgacggacg taacttctac catgttaact ggggttgggg tggagtctct gacggcttct
    57301 tccgtcttga cgcactaaac ccttcagctc ttggtactgg tggcggcgca ggcggcttca
    57361 acggttacca aagtgctgtt gtaggcatca aaccttagta tggaaatgca tttcgttaga
    57421 acagaacctg aggcacgccg catagctgaa accttttgtg ccgaaaacac acaaacaaaa
    57481 acccctatgc gcgtgcagca gttaagctat ccatcagaca cagatcactc aggtggtgag
    57541 ctatacatct atgctttgtc tcctgctgga tttatcatcg tatcaggaga taccagagcg
    57601 cacaccattt taggctattc ttttgataat aacctggacc tcaaccatga taatgtcaga
    57661 agtatggtag aagcttacca aaaacaaatc aactctttgg attgatcggt caaagtagct
    57721 tttgccccct caccactcgt ttaagacgac cgtgtttcta aaataccact accttttaag
    57781 tttcacgccg gcctaagcaa gtgtttgtct catggagcag actgtttcca tcgaaaagtc
    57841 acccattgat aaaggaggtc atcaacgcct actaatgatg acttccctaa gatgccaagg
    57901 taaaggactg agttctgtag agatgggact cagtcctttt acgatttttg ggagttattc
    57961 tagccatacc gtggcaagaa aacaacactc aaaaatagcc aacgtcagtt tctgttcata
    58021 catgactaca gccaaacacc acaacctaac ctatcctaaa cacagtggct ttctaacgaa
    58081 cagtcacaac gagcagcaac accaaaaagt aagattaagc tacgtttaag actaatgata
    58141 taagataaca gtaattatta atgagaaaag aggctcaaaa ggacatgaaa caaatgaata
    58201 aactcattac aggagtggta acgctggcga cagtcgtgac cttatcagct tgtcaatcat
    58261 cacacaacaa caccaaactc gtctcaatga aaggagacac catcactgtt agtgacttct
    58321 acaatgagac caaaaacaca gaactcgcac aaaaagccat gttaagcttg gtgattagcc
    58381 gcgtttttga gacacaatat gccaacaaag tctctgacaa agaggttgaa aaagcctata
    58441 aacaaaccgc agaccaatac ggtacatcct ttaagacagt cctagcacaa tcaggcttaa
    58501 caccagaaac ctataaaaaa caaattcgcc tcacaaaatt agtcgaatat gccgtcaaag
    58561 aacaagccaa aaacgaaacc atctcaaaaa aagactaccg tcaggcctat gacgcttata
    58621 ccccaaccat gaccgcagaa atcatgcagt ttgaaaaaga agaggatgcc aaagcagcac
    58681 ttgaagctgt caaagctgaa ggggcagact ttgcagctat tgccaaagaa aaaaccattg
    58741 cagccgataa aaaaacaacc tacacgtttg actcaggcga aacaacccta ccagcagaag
    58801 tagttagagc tgcatcaggc ctcaaagaag ggaacagatc agaaatcatc acagcgcttg
    58861 atccagccac ctcaaaacgc acctaccata tcatcaaagt caccaaaaaa gcaactaaaa
    58921 aagcagactg gaaagcgtac caaaaacgct tgaaagacat catcgtgact ggcaaattaa
    58981 aagaccctga cttccaaaac aaagtcatcg ctaaagctct tgataaagca aatgtcaaaa
    59041 tcaaagacaa agcatttgcc aatatcttag cccagtttgc aaaacctaac caaaaacaac
    59101 ctgcccaaaa atagagggtt gccagtttat ttccctaagg ttgcttaaaa agacagccct
    59161 agccatcact ccccttttca aaacaccgat aatggaaacg tgtcctatac tgatggtcta
    59221 gggcaatgtc ataaagctaa agactctatc ccaataagga tagagtcttt aatgttttaa
    59281 aaccagtcag caaaaaaatt cacgctaagt ctagaatgag gcttagcgtg aatggtatca
    59341 gtgatagtcc gttaaactag ctgattggga gtcagaaact ctccttaccc aatctgacta
    59401 tacccccagt accagaggtg tctcatcgca gaagtagcaa tcagataatc gtctgataag
    59461 ctcttgtcct caagcaactg atgagtctcg tcgcacgggc catgagctgc cggtggctga
    59521 tagccagtag gctcatcagc caaaactttt ttggagtaac gctttggtct cagacggcgc
    59581 cagagggttg agagaggggt gagaaaaaaa cgatggatca tcttggcctc cttgtctaat
    59641 gatagtcacc ttaacagaca aaagtgtcaa taatgtcatt ttaagaagaa aaagattaaa
    59701 aatcaaggtc acaaactttc ctttgttaaa aaaacgagac cctaacaaag accctaaata
    59761 cccctcgcac ctgagcttct ccttgcgcag ctatcttgcg cactcagttg tctccaggct
    59821 agtgatagcg ataccattat tgtcctatag gctatcgcga caaccccttt tttcgcttca
    59881 acgaggccga cacagctgtc atgacagaaa aaatacctct gcctatctaa gggaccatta
    59941 atttttctct caccaaaaaa ctgattttag aaacgaaaaa gcatggtgta taataaagtt
    60001 cggaacaatt atgacataat aatgaaagta aggttaacta aacattgaca aattgtaagt
    60061 ataaacttag aaagttatct gtagggctcg tctccgtcgg aacgatgctg atagctccga
    60121 cagttttagg acaggaggtt agtactggtg ctagcagtac tgagacgagt gctagtacta
    60181 atactagtac cgctagcgct ggtaccagta cgagtgagac agctgccagc ggaactggga
    60241 gtgaagcagc tgtagtatct agcgaaggaa gtcagagttc agaatctgga caagcctcaa
    60301 cacaacctca agcacagact ttagaacaat cagcagcaac gtcgccatca tcgaactctt
    60361 ctactagtag tagtgaagat aaagctccta aggcagcaag cactaaatca tcttcagcaa
    60421 ctgtggctag ctctagtaat ggtagcaatc aaggtgctgg tgctgaagat gcaccacaga
    60481 tgatggacgt ggaacggtat acagttgata gggaaaaaac agagctaaat attaaagacg
    60541 gtaagactcc aaaaactagg aatagtgtcg ataaagatac aaagcttatt agaaaccgcg
    60601 atggcaaaca gcgtgatatt gttgatatca agcgtgaagt aaaagataat ggcgacggaa
    60661 ccttagatgt aaccttaaaa gtaacaccta aagaaattga taaaggtgcc gatgttatgg
    60721 cccttttaga tgtctctaaa aagatgacgg atgctgattt taaaaacgct aaggataaga
    60781 tcaagaaatt agtcacaacc ttaacgagta aatcagcgag taactcagat aatgatgagc
    60841 ataaacataa ttctcgaaat tcggttcgtc tgatgacctt ttaccgtgag attagcaacc
    60901 caattgatat atcgggaaaa actgatgctg aacttgataa attattagac gatcttcgag
    60961 taaaagctaa agctaattat gactgggggg ttgatttaca aggcgctatc cacaaagctc
    61021 gggaaatttt taataaggaa aaagagtcaa aaaaacgcca gcatatcgtc ttgttctctc
    61081 aaggcgagtc gacttttagt tatgatattc aaaagagtga gaaagagaaa agtagcaatt
    61141 tatctcgtat aaacgaaaaa attacctcct ctaatccgct gttgccctgg ccaccaattt
    61201 ttgatcatac gcatcaaaat ggagatatga ttaatgatgt tagagcttta attgcatttg
    61261 ctagtaagct aggtataaag aatttatcat ggattgaaac atcacttagt gcgttaagcg
    61321 taggaagtaa cttgcttggt tctgtttttg gtggaggtgg actaggcgag tacctaactt
    61381 taaaagaata tgattcacaa aaattaaatg aagaccaatt tgattatact aaacgcgtag
    61441 gcgaaggata tcattatcat agtttttcaa atagggaatc tgaggataaa atgcctcttg
    61501 aaacagaaat taaaaaagct ttagaagctg ctttaccaaa attcgaagaa aataactggt
    61561 ttaccaaagt actaaaatac tttggattga aagataaagc tgaacaagcc aaacttgatg
    61621 taatcatgaa agtgattaaa agtgtcttct acaagcgcca gtaccactat tataatcaca
    61681 atctctcagc gatagccgag gctaagatgg cgcagaaaga gggcattacc ttctattccg
    61741 ttgatgttac tgctttaaac accgctagaa gagtgaagcg acaaacagca gtgctaaaga
    61801 acactaagga agaagaacgt aataagaagt ttgatgagta tctgaaaaag atgtctgaag
    61861 gcggtaacgc attttttaac gatgtggata aggcagataa gttcaaagac actttaacaa
    61921 aacttacgat taaagacgag tttgacggca aggttagtgt cgataaaact tcatatcaat
    61981 ccagtagtgc aatcaactat tctgaagcta gtaatagttt ttggcgtact accaaagaaa
    62041 gtctcacttg gaccatttcc aaagagcagt tgaaaaaagc ctttgaagat ggaaaaccgt
    62101 taaccttcac ctataagctt aaagttgata acaacaagtt taaaacagct ctcgaggaaa
    62161 ataataagaa gaagagaaca aaacgttcta cacctacaga aaatgaaaac tctgtcacag
    62221 aaaaaatcat ttcaaatact actacctacg aaattaatga acaaaaagtt gaagggaaca
    62281 aacttggtga tgttagtctg acatacagta aattcaaggt tcctgtacca cagattgatg
    62341 ggcatgttat tgagccacaa gcaccgacat tacctaagtt acctcctgtt attgagcatg
    62401 gccctaactt tgagtatgag gaagaaacag gttatcagtt accacttaaa catggcagca
    62461 atgcaccaga cacacaagtg acaattgaag aagacacagt tcctcaacgt ccagatatcc
    62521 ttgtaggcgg tcagagtgga ccggttgaca tcaccgaaga tacccaacca ggtatgtcag
    62581 gctcaaatga cgcgacagtt gtcgaggaag acacagcacc taaacgtcca gatgtccttg
    62641 ttggtggtca aagtgagcca atcgatatca ctgaagatac ccaaccaagt gtgtcaggct
    62701 caaatgacgc gacagttgtc gaggaagaca cagtacctca acgtccagat atccttgttg
    62761 gcggtcaaag tgatccaatc gatatcaccg aagataccca accaggtatg tcaggctcaa
    62821 atgacgctac tgttatcgaa gaagatacga aaccaaaacg cttcttccac tttgataacg
    62881 agccacaagc accagaaaaa cctaaagagc aaccatctct cagcttacca caagctccag
    62941 tctataaggc agctcatcac ttgcctgcat ctggagacaa acgtgaagca tcctttacaa
    63001 ttgttgctct aacaattatt ggagctgcag gtttgctcag caaaaaacgt cgcgacaccg
    63061 aagaaaacta accctcgtta gtctagcgac cctaagcctt tggctttaaa aatttctcat
    63121 tatccccctc aaacaccggt acttcactga gatggcgctt taaaaaggcg ctagtctcaa
    63181 atcaggtatc ccctacggtt gagggggatt aatgggtatc acaacaagta aaaaggtata
    63241 atgatgaaat atgactaaaa aatttattaa atcagcagtg attctaggct tagcaagcat
    63301 aaccatcagc atgacgcaac ccgttgaagc catttcaaat cgcttagaat atcaagaaca
    63361 atataaacgt gtcaaagaag aactagacgc attaaaagaa aagagcccaa aattaggaga
    63421 acgttccctt tattttagat tggtgaatag atttctaggt tggtttggcg tagtctggga
    63481 cccactcgca atcaaagaaa ccgatcacct gttggacctc atcggacaag tcaattactt
    63541 ggtgagtaac accgagtttc aagcccctga gtatcaaaag gctaaaaaca aactagactt
    63601 agctgtagca ggctatgacc tctacctagc tagagagaaa aaacgtggtg atgctcctga
    63661 ttaccaagtg acccagctaa cgctaggaca gctcgaaact atcaaaacga agatacaaga
    63721 ggccctgaaa acatttgcac aagaggtcaa aacaatccaa caaaaaaccc cagacctatt
    63781 tccccatgct tatgttttaa acgctaagac cagtgctatc gatggtaaag cgcaaccctt
    63841 tttagtgaat ggttactacg atgtctttta taagcagttt ttattcacta ataaaaatga
    63901 cgggtataac tataataaag aagcagacaa tctgacctcg tatcaaaatt tgattaaaga
    63961 gctattagac ttaaaagctg agatcgatcg gttaacaaaa gacgatccta aaaacgatcg
    64021 tttagagacg ttaatgtggc aatcaaagtt caccttatct gactttcgga gaacttcacg
    64081 ccttagcgcc tactatacac aaggcgatta tgtcaaaacg gtggtcctat ctgaagaagc
    64141 tcccaacttg agaacagcaa aagaaaaggt caagacctta aaagggatct tgcatgatta
    64201 ctatgttgaa actaataagc cagaaaaagc taaagagtat cgtgtcgagg acgagacctt
    64261 gccgtctcaa cctgaggctc ctgttacacc tgaagctcct gctcctagtc ctgttcctgg
    64321 tcaaaaacca gcagaagctg agagatcgtc acaagctacg gagccagcta acccgtcaaa
    64381 agagaattcc tcaacagacg catctcaggg atctcacgat agtgaaaacc cagcgacaga
    64441 cagtccttct caacctcagg caccagacca aggcaatcac caaagccaag tgcctaacga
    64501 caagcctcaa acggacaaga cggacactcc taacgtccca gcccctccac agaacactcc
    64561 taacgcccca gccatcccac aggacacccc aaaagtgcct gaggctggtg gtcagagtgg
    64621 ccccgctggg aacgctgagg agaaagctcc tgactctgga cctaaagcgt ctgatcaaag
    64681 ctcgtctaaa gagtccccat ccgttggcga agacacgacc cctaatcagc cagatgtcct
    64741 tgtaggtggt caaagtgagc caattgatat caccgaagac acaatcactg acgctcctcc
    64801 gacagtatct gggcacaacg catcaacaca gccccaatct gtggtcgaag acacggcacc
    64861 tcagcgccca gatgttcttg taggtggtca aagcgagcca atcgatatca cccaagatac
    64921 ccaaccgggc atgtcaggct ctaatgacgc taccgttatc aatgaagata caaaaccaaa
    64981 acgcgtcttc cactttgaca acaaagagcc acaagcatca gaaaaagcgg cagagcaaaa
    65041 acttgctcct catgatagcc acacaactcc tcaagcttca gatgatacag cagcccctca
    65101 cttgcctgca tctggagata agcctgaaaa agcgtttgca cttgctgcct tgacaatggt
    65161 cgcagctgca gggctactca gcaaaaaacg tcgcaacacc gacaaaaact agtcgctgtt
    65221 agacacaacg catcactaag gccagtgcat ttgcactggc cttagttagg tttttatcaa
    65281 atagaggttt tttcatgaca attgctagcg tttcggtgta aaataaaggt aataaccagc
    65341 aaaggagcaa cccatgacaa agcaagatca gttaattgtt gaaaaaatgg aacaaaccta
    65401 tgagaccttt agcccaaagc tagcaaatct catagaagcc ctagatgcct ttaaagagca
    65461 ttatgaggaa tatgccacac ttagaaattt ttacagtagt gacgaatggt ttcggcttgc
    65521 aaaccaacct tgggatgata tcccgtgcgg tgtcctatct gaagacctcc tctttgatat
    65581 gatcggtgac cataaccaac tactagctga tatcttagac ttggccccta tcatgtacaa
    65641 gcatatgtaa ccatcgctaa cgtcacagat actacgatga caggacaaaa aaagcttgaa
    65701 aatctcaaaa aaaaacagat aaaaaacaga taatcgttag aaaaacagta gatgcgtctg
    65761 ttaaactaaa ggtatcaaaa caaaaggagc atttcatcat gaaattcaaa aaagtattag
    65821 tcattcctgc attagcatta gcagcaacat gctttttaac agcttgtggc acaaaaaaag
    65881 attctaaaaa agaagaagtt aaagaaatca aaatgtctga catcaaagac gacgcagtta
    65941 gcaaaaaaac aaaagtggtt gatggcgaag aagttacaga atacaccaca aaagatggaa
    66001 acgtgattca gattcctgca ggaaacgaag aaggcatgga atcaaaagat gctggtggat
    66061 caggcgctcc tgctaaaaac taagggttac aacaaagagc ataaggtgac tcgcaaacgt
    66121 tacgcatgac atgaggcagt ctgcctaaga tggtaactca cttatcataa tgcctaaata
    66181 gccaaacaca ctaactcgca aatgtacaaa atcatatacc cgtgcttatg tgagcgaacg
    66241 gttatatgat ttttgttttc caaaaacaag aaaagaacgc taaaatagcc agtttgtcgt
    66301 gtttcaagct acgaaaaagg aagtgctaaa atgaaaaaaa gatccattat acctgtcatc
    66361 ttactgttgg tcatcggatt aatcgttggt gttaagcgtc atcatgacta gtaggtcttg
    66421 ctagtgaccg ttcaaaaggg ataacgttgg tatggtataa ccataaaaat cgtataaaaa
    66481 gaaaaaatag ctattgagga gaaagtatgt ttcagttaag aaaaaaaatg acgcgcaaac
    66541 aattagcctt gttgagtgct ggagtgttga cctgtgtggt tggtggtagc tacttgataa
    66601 tgaaccatca acaacaagaa attgtctcta gtgtcaacaa agtaaaagcc ttaaccataa
    66661 aagaagccat ggaacaagga aaagatatca gcttgacctt agctggcgaa gtaacagcta
    66721 acaacagcag caaagtcaaa atcgactcaa gtaaaggaga agtcaaagat gtctttgtca
    66781 aaaaaggcga tgttgtcaaa gtaggacaac ccttgtttag ctatgaaacg tcacaacggt
    66841 taacggctca aagttcagaa tttgatgttc aaaccaaagc caatcaactc caagttgcta
    66901 aaaccaatgc agcattgaag tgggaaacct acaatcgcaa ggtcaatgaa atcaacaccc
    66961 taaaatctcg ctacaacact gcaccagatg agagcttact agagcaaatt cgcagcgcag
    67021 aagacagtgt atcccaagca ctaagcgatg ccaaaacagc agatagcgat gtcaaaaccg
    67081 ctcaaatcga actcgataaa gctaatgcta ctgccgcaac ggaaaaaggt aaactagagt
    67141 atgacaccgt taagtcagac accgcaggaa ccattgttag tctaaatact gatttgccaa
    67201 atcaatcaaa atccaaaaaa gaaaatgaaa cttttatgga aattatcgac aaatcaaaaa
    67261 tgttagtcaa aggtaacatc agtgaatttg accgtgacaa gttaaaaatc ggtcaaaaag
    67321 tcgaagtgat tgaccgcaaa gacaactcta aaaaatggac tggaaaagta acccaagttg
    67381 gcaacctcaa agcagaggaa aaaggccaag gtcaaggcca aggtggcaat gaccaacaag
    67441 ataatccaaa ccaagcaaaa ttcccttatg ttatcgaact tgaccaatca gacaagcagc
    67501 cactcattgg ttcacacacc tatgttaatg tgctcaacaa tgttccagaa gctggcaaga
    67561 tcgtattgaa agaaaccttt acaatggcag aaaatggaaa aacctatgtg tggaaagttg
    67621 ataaaaacaa ggtcaaaaaa caagaaatca agactaagcc cttctcaaaa ggttatgttg
    67681 aggtgacaag tggcttgact atgcaagata agattgctca gccgcttcct ggcatgaaag
    67741 acggtatgga ggtaggaagt attgttaaac cttaaagata ttcgaaaaag ctatcatctt
    67801 gggactgaag aatttgcgat tttaaaagga atcgatttag aagttaacga gggtgacttt
    67861 ttagccatca tgggaccatc aggttcggga aagtcaacat tgatgaatat cattgggtgt
    67921 ttagataagc ctggctctgg ctcatatgcc attgaaggca gagacgtgtc atccttatct
    67981 gataatgaac ttgctgattt gcgtaatcaa aaaatcggct ttgtttttca aaactttaac
    68041 ctgatgccca agctaacagc ttgtcaaaat gtcgaattgc ccttgactta tatgaatgtt
    68101 cctaaaaaag agcgtcgcaa acgagcccta gagatgttaa agctagtagg attagaagaa
    68161 cgtagtgaat ttaaaccgat ggagctatct ggtgggcaaa aacagcgtgt agcgattgca
    68221 agagctttag tcactaaccc gagttttatc cttggtgatg agccaacagg tgcactagac
    68281 acaaaaacca gcgtccaaat catggaccta tttaaacaat tcaatgataa cggcaaaacg
    68341 attattatca tcacacacga gcctgaagta gctgctttat gcaaaaagac ggtgatccta
    68401 agagatggta atatagaaca ttccgatata gagtaaaggg ggaaaataat ggaagatatt
    68461 attgcagctt taagctctat attatcacac aagatgcggt caattttgac aatgctaggg
    68521 attattatcg gtattggtgc cattatcgca atcttttcaa tcatcgaagg taataccgaa
    68581 aataccaaaa gacagttgat tggtggcagc aataacacta ttaacattgt gtttaacaaa
    68641 aaaagtagta ttgaccctaa atttccagac aagtcaaatg ctaaaaaacc agactatctt
    68701 ccttttatgg ctgaagaaga gcttagcaaa atacagcaag tcaaaggcgt caaaaatgcc
    68761 ctgatctcat atggtattga tgacaaagtc taccatctag gccaaaaatc atctgcaaag
    68821 atttctgcca tcacaaaaaa cgtagctgaa gtgagacgca tgacatttat taaaggcagt
    68881 gacttttcag acaaagactt tattgaccaa aaacaggtga tttaccttga aaaaagcttg
    68941 tatgagtcac tatttccaaa agacgatggc cttggaaaat ttgtcgaagt gatgggaaat
    69001 cccttcaggg tcattggggt gtttgaatca aaagaacaaa gtggcctcac aagtgggact
    69061 gagaaaattg cttatatccc gctacatcag tggtataata ttaatggtgt agtggatgcg
    69121 acacctgaga tcacgatcca gacctatcgc gcagatgacc tcaaacctgt agcaaagcgt
    69181 gtcagtgata tgctcaatca aacgatccct aaatcagatt atatgtttgg tgtcatgaac
    69241 cttaaagaat ttgaacgcca actagacaac ctaaacaaat ctaattttgt gttattagct
    69301 ggtattgcta gtatctctct tattgtaggt ggtattggtg tgatgaacat tatgctagta
    69361 tcagttaccg aaagaacgag agaaattggg atcaaaaaag cgcttggcgc tagacgtaag
    69421 cttattttaa aacaattttt aattgaagcg gtcattctaa ccttgctagg tggtgtgata
    69481 ggggttattt cagggatggt atcaggattg atcatcacaa gatcactcga atatccctat
    69541 atcctatcct tgttctcagt tgtcttgagt ttagcgtttt gttgtattat agggattgtc
    69601 tttggactat taccagccat taaagcgtct aagctagacc caattgaagc attgcgattt
    69661 gaataatcaa ccaaacaagc ataaaagtca aaaaggatga ccctttgatg tcatccttag
    69721 ctgcttgata cactaaacgc caatctagaa agggaagtta tgtttaaaat attagtagtt
    69781 gaagatgatg ataccatcag tcaagtgatt tgtgagtttt taaaagcgaa taactatgat
    69841 ccagattgtg tatttgatgg ccaagctgcc ttagacaagt ggcagacaac gtcttatgat
    69901 ctgattattt tagacatcat gctcccatcc ttaagtggct tagaagtgct aaaaacaatt
    69961 cgaaagacat cagatgtccc tattattatg ctaacggcat tagatgacga gtacacacag
    70021 cttgtaagct tcaaccattt gattagtgat tatgtgacta aaccattttc accactcatt
    70081 ttaatcaaac gtatcgaaaa tgtattacgc gtctctactc cagatgaaaa gcgccaaatc
    70141 ggagacttac ttgttgatga gaccgaacat agcgtctatt ggcaaggaac attggtcaaa
    70201 ctaaccaaaa aagagtatga cattattgat tatttagcaa aacgtcacca aaagattgtc
    70261 accagagacc aattgatgga tgacatatgg ggctattctg aactggacac gcgtgtcctt
    70321 gacaaccaca tcaagaacct tcgtaaaaaa atgacgggta ttcccctcaa gacaattaca
    70381 ggcatgggct atttattggg agagcgtgag tgagactaat caaaaaaacc tttttggtca
    70441 tcaatggctt aattattgta gtggttacct ctattttgtt agtgctttat tttgcaatgc
    70501 caatttatta caccaaagtc aaagacaaag aagttaagcg tgaatttgac caaacaagca
    70561 agcaaatcaa aggcaaaacg gtaaccgaga ttagagatat cctaacaaaa aaaatcaaca
    70621 aagataatat ttggtacagc ttagtagaca gtgataacca actgctctat ccttccttgc
    70681 agctgttaga cggcgtcagt gaaagcaaag acagtcaaaa tgttaatatc gtcaccacct
    70741 ttgacaactc ttattctaat gttaaggtga tgagtcaaaa agtaacccta cgcgatggaa
    70801 aaaagatgac attgcttggg caatcttcac ttcaacccgt aacagatgct agcaaagttc
    70861 tccttgacct ctacccgtca ctattgattt tttcagtgac cgtagggagt attgtcgcct
    70921 acttatatag taggacttct agccggcgta tccttagcat gtcacaaacc gccaaaaaaa
    70981 tggtcaacct agaaccaaac ttaacgtgta ccattcacgg caaagatgaa atagcaatgt
    71041 tggctagtga tattaaccgt ttgtatgcga gtctttcaac gagcatcaaa tccttgcaaa
    71101 aagagtatga aaaagcttct gattcagaaa gagagaaatc tgagttttta cgcatgacat
    71161 cgcacgagct aaagacacca atcaccagtg ttatcggaat gattgatgga atgctctata
    71221 atgttggtga ttttgcagat cgtgacaaat atttgcgaaa atgccgagac gtccttgaag
    71281 ggcaagctca actggttcaa tccattttat ctttatctaa gattgaaacc ctagcttctc
    71341 aaaatcaaga actgttttca ctaaaaagca gcctagaaga agaaatggaa gtctttctcg
    71401 tcttatcaga actaaaacac ctcaaagtga ctatcaatct cgaagaacaa ttcgtcaaag
    71461 ccaataaagt atacctacta aaggcgatta aaaatattat tgacaatgcc tttcactata
    71521 ccaaatcagg cggccaagtg atgattcaac taaaagacaa ccaactagtg attaaaaatg
    71581 aagcagagac attattgaca caacagcaga tgaaacagtt attccaaccg ttttatcgac
    71641 cagattatag tcgtaacagg aaagacggtg gtacaggatt ggggctgttt atcacccacc
    71701 agattcttga tcagcatcat ctggcttatc gctttgttgt tcttgatcaa agatggatgg
    71761 tatttacgat tgattttcca tcccatcatg acgattgatc cacactagta ggacgacaaa
    71821 agccatcaat cactaaccaa gccttgacct ttacccatca ttgtttaggc aagtataaaa
    71881 aagaggagag aaatcatata tgaagaaaag gaaattgtta gcagtaacac tattaagtac
    71941 catactctta aacagtgcag tgccattagt tgttgctgac acctccttgc gtaataacac
    72001 atcatccact gatcagccta ctacagcaga tactgatacg gatgacgaga gtgaaacagc
    72061 aaaaaaagac aaaaaaagca aggaaacagc gtcgcagcac gacacccaaa aagaccataa
    72121 gtcatcacac actcacccaa cccctccttc aaatgatact aagcagaccg atcaggcatc
    72181 atctgaagct actgacaaac caaataaaga caaaaacgac accaagcaac cagacagcag
    72241 tgatcaatcc accccatctc ccaaagacca gtcgtctcaa aaagagtcac aaaacaaaga
    72301 tggccgacct accccatcac ctgatcagca aaaagatcag acacctgata aaacaccaga
    72361 aaaatcagct gaaaaaaccc ctgaaaaagg accagaaaaa gcaactgaaa aaaccccaga
    72421 gccaaatcgt gacgctccaa aacccatcca acctccttta gcagcagcag ctcctgtctt
    72481 tgcaccgtgg agagaaagtg acaaagacct gagcaagcta aaaccaagca gtcgctcatc
    72541 agcggcttac gtgagacact ggacaggtga ctctgcctac actcacaacc tgttgtcacg
    72601 ccgttatggg attactgctg aacagctaga tggttttttg aacagtctag gtattcacta
    72661 tgataaagaa cgcttaaacg ggaagcgttt attagaatgg gaaaaactaa caggactaga
    72721 cgttcgagct atcgtagcta ttgcaatggc agaaagctca ctaggtactc agggagtcgc
    72781 taaagaaaaa ggagccaata tgtttggtta tggcgccttt gacttcaacc caaacaatgc
    72841 caaaaaatac agcgatgagg ttgctattcg tcacatggta gaagacacca tcattgccaa
    72901 caaaaaccaa acctttgaaa gacaagatct caaagcaaaa aaatggtcac taggccagtt
    72961 ggataccttg attgatggtg gggtttactt tacagataca agtggcagtg ggcaaagacg
    73021 agcagatatc atgaccaaac tagaccaatg gatagatgat catggaagca cacctgagat
    73081 tccagaacat ctcaagataa cttccgggac acaatttagc gaagtgcccg taggttataa
    73141 aagaagtcag ccacaaaacg ttttgaccta caagtcagag acctacagct ttggccaatg
    73201 cacttggtac gcctataatc gtgtcaaaga gttaggttat caagtcgata ggtacatggg
    73261 taacggtggc gactggcagc gcaagccagg ttttgtgacc acccataaac ctaaagtagg
    73321 ctatgtcgtc tcatttgcac caggccaagc aggagcagat gcaacctatg gtcacgttgc
    73381 tgttgtagag caaatcaaag aagatggttc tatcttaatt tcagagtcaa atgttatggg
    73441 actaggcacc atttcctatc ggacgttcac agctgagcag gctagtttgt tgacctatgt
    73501 tgtaggggac aaactcccac gaccataaac ccacaaccaa gaagctacct gcctgttgac
    73561 caatctcaaa aagagatagc gtcaacttag aatgaggttc atcagatgat aaagaaagtg
    73621 accaccccga gtcaaaaaat aaaaaaacgt gttcgtaatg gctacctctt aaaactaggt
    73681 acagcctgtt tactcttaag tatactcagt tatggcattg gtcttttggg ccagcctagc
    73741 atggaaaata cgtttatggg aatagcgagt gttgccatgt taggaagtgt ctgtttcttt
    73801 attatctttg ctctaaatcg tatctttgac gcactagagg acaatttgcg agattagagt
    73861 aataggtcaa ataatcttcc aataatttag agcataagct aagttattgg aagttttttt
    73921 gtcttttgag agccatgatg ccatcaaaaa gccaaacact ccttatgatg tgagagtcac
    73981 atgactaaaa ttaaaagcaa aatagacccc aaagccctgt tttctcaaaa cagccaacga
    74041 aaaaagacaa gttaaccagt tcataaaaaa catcgtagaa acattttcaa gagctaatgt
    74101 tggtgtaaat tgactgaagt atgatagaat ttttaatgaa tgtgacaata atgtcacaga
    74161 taaaaaccga aaacagcaaa aataattaaa ttgaatataa aaaagttaat taagtgagtg
    74221 ataataaaaa aatgaagttc aaaaaatata aataaaataa aacaccagaa ctgctaaaag
    74281 cagtgaatga cataaatgtc gctaaaaaaa tagatagaag agtctaaaat ttcagtttta
    74341 ggtcacgttt tatgaataga aatcaggatg atgaccctaa gttgtgattt gcgcgtcatt
    74401 gactgctttc ctcgttttaa tgaaagaatt tgaaagatat tttatggtat acttttcctt
    74461 aatatggttc atacggactt gataaatcta tttacaaaaa taataaaaaa ttaagataag
    74521 gacatgaagt taatgcatgt aagtaaatta tttactagcc aacaatggag agaattgaaa
    74581 ctgatctcat atttaacaga aaactccaat gctatcggag ttaaagataa ggagcttagc
    74641 aaggctctca atatttccat gttaacatta cagtcatgcc tcactaatat gcagtttatg
    74701 aaagaagtag gtggaattac ctacaaagac ggctatatta acatttggta tcaccagtgt
    74761 tgtgggctac aagaggtcta tcaaaaagct cttcgagaat cgccttcttt gaaattacta
    74821 gagcttttgt ttttcagaga ctttagttcc ttagaagagt tagctgaaga gctgtttgtc
    74881 agcttatcta ccctcaaacg cctcatcaaa aaaaccaaca cttacttgtc tcataccttt
    74941 gctattagta tcgtgacaag tccagtgcag gtatcaggag atgagaggca aatccgcctg
    75001 ttttacctca agtatttttc agaagcctat aaaatctcag aatggccatt tggggacatt
    75061 ttaaacctga aagactgtga acgcctattg agcttattga tcaaagaagt agatgtcaaa
    75121 gttcatttta cactatttca gcacttaaaa atcttaagtg gtgtcaactt gatccgttac
    75181 tacaaggggt attcttgcag ttataacaat aaaaaaacca gtcaccgttt ttctcaactc
    75241 atccaacatt cctcagaaat ccaggatctt tctcgcttgt tctacctcaa atttgggtta
    75301 catctcgacg agtataccat agctgaaatg ttttctaacc atcttaacga caagctagaa
    75361 attggctgtg cttttgagat tatcaatcaa gacccaacat caggaggcag acaagtaacc
    75421 aactggatcc atctattaga tgagatggaa atcaagctca atctcagcat caccaataaa
    75481 tacgaagttg ctgtaaccct ccataacgct tcggtgttaa acgaagaaga cattacagcc
    75541 aattatttgc tgtttgatta taaaaagagt tacctgaact tttaccaaaa agaacaccct
    75601 cgcatttatg aggcctttgt gacaagtgtc gagaagctga tgcaggcaga taatgctcaa
    75661 gttagcaaag aattgatcaa tcagctcact tattgtttct ttattacctg ggaaaatagt
    75721 ttcttaaaag taaatcaaag agatgaaaaa gtaagactcc tagtgataga gagaagttac
    75781 aatagtgtcg gtaatttttt gaaaaagtac atcggtgagt ttttcagcat tactaatttt
    75841 gatgagttag attgtttgac aattgatcta gtagagattg aaaaacagta cgatgttatc
    75901 gtgacagatg ttatggtggg taaaagcgaa gagttagaga ttttcttttt ctacaagatg
    75961 atcccagaag ctattattga tagattaaac gaatttttga acgttagttt cacagataac
    76021 aacgttatgg tcaaaaacct cgaagcccct tccccttcaa aatctcatag tgacaaagag
    76081 gtacaaaagc cagacaattc agttaaacaa gcaacatcat cataggattt cagacgtcat
    76141 ggtaagaaaa aaagaatcat ttacagccca tagaggtgag gtcaaaagct gaaaacagct
    76201 caaaaaaact gacctttacc ttttggcttt ttttatttag aataatttta ttggagagat
    76261 gcttaataat ttaagcacaa ttcttagaaa ttaagaaata aggagtaaac aatgtctaaa
    76321 agaaatccaa acaagcacta ctcactgaga aagttaaaaa caggtactgc atcagtagca
    76381 gtagctttga cagttttggg gactggatta gcaaacacaa ctgatgtaaa ggctgagacc
    76441 gtaggtcgct ttagtgatga acaagttaga aaggctcgtg aaaaagcaat cgaagacgtg
    76501 tttgatggct atactggagc tcgttctgtt tatcaatctg ggaatctgcc taataggtta
    76561 actcctacaa aacttagcaa attaatgcaa cagatgtata aggagacttt acaaaagaaa
    76621 gaagaactgg ataccctatc taaagctctt acgcacacta ttgagaaaaa gattgagtca
    76681 gaaaatgctt acaagaaaga gcttggacag ctcaaagcag cggcagaagc agaagctcaa
    76741 aaagcattag atgcactaaa taacaaaaac aagcaaatct cagacttaac caacgaaaac
    76801 gcacagttaa aagaagccat tgaaggttat gtgcaaacta tccaaaacgc tagccgtgaa
    76861 atcgcagcaa aacaacaaga acttgcggct gcaaaaagcc agttagaggc aaaaaatgct
    76921 gagattgagg cattgaaaca acaagatgcc tctaagactg aggaaattgc taaattgcaa
    76981 tcagaagcag caactttaga aaaccttcta ggttcagcta agcgtgagtt gactgaattg
    77041 caagctaagc tagatacagc aactgctgaa aaagcaaaac tagaatcaca agtaacaacc
    77101 ttagaaaacc ttctaggttc agctaagcgt gaattgactg atctgcaagc taagctagat
    77161 gcagctaacg ctgaaaaaga aaagctccaa tcacaagcag cagccctaga aaaacaacta
    77221 gaagcaacta aaaaagagtt agctgattta caggctaaat tagcagcaac caaccaagaa
    77281 aaagaaaagt tagaagctga agcaaaagct cttaaggagc aattagcaaa acaagctgaa
    77341 gagcttgcta agctaaaagc agataaagct tcaggagctc aaaaaccaga tactaaacct
    77401 ggcaataaag aggttccaac aagaccatca caaacaagaa caaacactaa taaagctcct
    77461 atggctcaaa caaagagaca attaccgtca acaggcgaag aaacaaccaa cccattcttc
    77521 actgcagcag cattgacagt gatcgcatct gcaggcgtac ttgccctaaa acgcaaagaa
    77581 gaaaactaag cccaacccac actatctttt ctagcccaag aaaaaaacaa aaaaagagga
    77641 agaccattcc tctttttttg aacggttaaa cagtaaaaag gtcaaaaagg tactaaagtc
    77701 tcaaaaacct ggtctttacc ttttaccact tattctttag aatagaatta ttagagagaa
    77761 gtcttagaaa aatgaggcta attccctaaa gatgaaaaaa taaggagcaa ataatggcta
    77821 gaaaagatac gaataaacag tattcgctta gaaaattaaa aacaggtaca gcatcagtag
    77881 cggtcgctgt ggctgtttta ggagcaggct ttgcaaacca aacaacagtt aaggcggaca
    77941 gtgacaatat taatagatct gtctctgtca aagataatga aaaagaatta cataacaaaa
    78001 ttgcagacct tgaagaggaa agaggagaac atctagacaa aatagatgaa ctaaaagaag
    78061 aactaaaagc aaaggagaaa agttcagaaa acgtagaacg tcactacctc agaaaactag
    78121 atcaagaata taaagaacaa caagaacgtc aaaaaaatct agaggaactc gaacgccaaa
    78181 gtcaacgaga agtagaaaaa cgttatcaag aacaactcca aaaacaacaa caattagaaa
    78241 cagaaaagca aatctcagaa gctagtcgta agagcctaag ccgtgacctt gaagcgtctc
    78301 gtgcagctaa aaaagacctt gaagctgagc accaaaaact caaagaggaa aaacaaatct
    78361 cagatgcaag ccgtcaaggc ctaagccgtg accttgaagc gtctcgcgaa gctaagaaaa
    78421 aagtagaagc agacctagct gctcttactg ctgagcacca aaaactcaaa gaggaaaaac
    78481 aaatctcaga cgcaagccgt caaggcctaa gccgtgacct tgaagcgtct cgcgaagcta
    78541 agaaaaaagt agaagcagac ttagccgaag caaatagcaa acttcaagcc cttgaaaaac
    78601 taaacaaaga gcttgaagaa ggtaagaaat tatcagaaaa agaaaaagct gagttacaag
    78661 caaaactaga agctgaagca aaagctctta aagagcaatt ggctaaacaa gctgaagaac
    78721 ttgccaaact aaaaggcaac caaacaccaa acgctaaagt agccccacaa gctaaccgtt
    78781 caagatcagc aatgacgcaa caaaagagaa cgttaccgtc aacaggcgaa acagctaacc
    78841 cattctttac agcagcagct gcaacagtaa tggtatctgc aggtatgctt gctctaaaac
    78901 gcaaagaaga aaactaagct attagactga tgctaaagct aagagagaat caaatgattc
    78961 tctctttttg agtggctaag taactaacaa tctcagttag accaaaaaat gggaatggtt
    79021 caaaaagctg gcctttactc cttttgatta accatatata ataaaaacat taggaaaata
    79081 atagtaatat taagtttgtt tcctcaataa aatcaaggag tagataatgg ctagacaaca
    79141 aaccaagaaa aattattcac tacggaaact aaaaaccggt acggcttcag tagcggttgc
    79201 tttgaccgtt ttgggcgcag gttttgcaaa ccaaacagaa gtaagagctg aaggggtaaa
    79261 agcgactacg aacttgccag aggaggctaa atatgccgca ttgaaagatg agaatactgg
    79321 tttacgtggt gatcagacaa aattagtaaa aaaacttgaa gaagaacaag agaagagcaa
    79381 aaatctagaa aagcaaaaac aagagttaga aaaccaagcc cttaactttc aagatgtaat
    79441 tgaaactcag gaaaaagaaa aagaagatct caaaacaact ttagctaagg ctactaaaga
    79501 aaacgagatc tcagaagcta gccgtaaagg gttaagccga gacttagaag cttctcgagc
    79561 agctaaaaaa gagctagaag ctaagcatca aaaattagaa gcagaaaaca aaaaactaac
    79621 agaagccaat caggtttcag aagctagtcg taaaggtcta agtaacgact tagaagcttc
    79681 tcgagcagct aaaaaagaac tagaagctaa gtaccaaaaa ttagagactg atcaccaagc
    79741 cctagaagct aagcaccaaa aattagagac tgattaccaa gtttcagaga ctagccgtaa
    79801 gggtctaagc cgtgaccttg aagcatcacg tgaagctaat aagaaggtta catctgagtt
    79861 aacacaagca aaagctcaac tcgcagcgct tgaagaaagt aagaaattat cagaaaaaga
    79921 aaaagctgag ttacaagcaa aactagatgc acaaggaaaa gccctcaaag aacaattagc
    79981 aaaacaaact gaagagcttg caaaactaag agctgaaaaa gcggcaggtt caaaaacacc
    80041 tgctaccaaa ccagctaata aagaaagatc aggtagagct gctcaaacag ctacaagacc
    80101 tagccaaaat aaaggaatga gatcacaatt accgtcaaca ggcgaagcag ctaacccatt
    80161 ctttacagca gcagctgcaa cagtgatggt atctgcaggt atgcttgctc taaaacgcaa
    80221 agaagaaaac taagccttta gaacttggtt tttgtaacgg tgcaatagac aaaagtaagc
    80281 aaggccaaaa actgagaaag tcctaaaaag ctggccttta cccctcaaaa ttaatgtttt
    80341 ataataaaga tgttagtaat ataattgata aatgagatac atttaatcat tatggcaaaa
    80401 gcaagaaaaa tagctgtatc atatgcaaat aacccctgtt tgctctttaa aaaagacgtt
    80461 atccttattt ctccacgcac agatggacag ctaggagaga atcgtttgat tctctctttt
    80521 cttaatggtc ataaagacaa agtctctcat catgaaagga cgacacattg cgtaaaaaac
    80581 aaaaattacc atttgataaa cttgccattg cgctcatgtc tacgagcatc ttgctcaatg
    80641 cacaatcaga cattaaagca aatactgtga cagaagacac tcctgctacc gaacaagccg
    80701 tagaaacccc acaaccaaca gcggtttctg aggaagcacc atcatcatca aaggaaacta
    80761 accccccaca aattcctgat gacgcagaag aaacagtagc agataaggct aatgatccag
    80821 cccctcaagc tcctgctaaa actgctgata caccagtaac ctcaaaagcg actattaggg
    80881 atttgaacga cccttctcag gtcaaaaccc tgcaggaaaa agcaggcaag ggagctggga
    80941 ctgttgttgc agtgattgat gctggttttg ataaaaatca tgaagcgtgg cgtttaacag
    81001 acaaaaccaa agcacgttac caatcaaaag aagatcttga aaaagctaaa aaagagcacg
    81061 gtattaccta tggcgagtgg gtcaatgata aggttgctta ttaccacgac tatagcaaag
    81121 atggtaaaac cgctgtcgat caagagcacg gcacacacgt gtcagggatc ttgtcaggga
    81181 atgctccatc tgaaacgaaa gaaccttacc gcctagaagg tgcgatgcct gaggctcaat
    81241 tgcttttgat gcgtgtcgaa attgtaaatg gactagcaga ctatgctcgt aactacgctc
    81301 aagctatcag agatgctgtc aacttgggag ctaaggtgat taatatgagc tttggtaatg
    81361 ctgcactagc ttacgccaac cttccagacg aaaccaaaaa agcctttgac tatgccaaat
    81421 caaaaggtgt tagcattgtt acctcagctg gtaatgatag tagttttggg ggcaagaccc
    81481 gtctacctct agcagatcat cctgattatg gggtggttgg gacacctgca gcggcagact
    81541 caacattgac agttgcttct tacagcccag ataaacagct cactgaaact gctacggtca
    81601 aaacagccga taagcaagat aaagaaatgc ctgttctttc aacaaaccgt tttgagccaa
    81661 acaaggctta cgactatgct tatgctaatc gtgggatgaa agaagatgat tttaaggatg
    81721 tcaaaggcaa aattgccctt attgaacgtg gcgatattga tttcaaagat aagattgcaa
    81781 acgctaaaaa agctggtgct gtaggggtct tgatctatga caatcaggac aagggcttcc
    81841 cgattgaatt gccaaatgtt gaccagatgc ctgcggcctt tatcagtcga aaagacggtc
    81901 tcttattaaa agacaatcct aaaaaaacca tcaccttcaa tgcgacacct aaggtattgc
    81961 caacagcaag tggcaccaaa ctaagccgct tctcaagctg gggtctgaca gctgacggca
    82021 atattaagcc agatattgca gcacccggcc aagatatttt gtcatcagtg gctaacaaca
    82081 agtatgccaa actttctgga actagtatgt ctgcgccatt ggtagcgggt atcatgggac
    82141 tattgcaaaa gcaatatgag acacagtatc ctgatatgac accatcagag cgtcttgatt
    82201 tagctaaaaa agtattgatg agctcagcaa ctgccttata tgatgaagat gaaaaagctt
    82261 atttttctcc tcgccaacaa ggagcaggag cagtcgatgc taaaaaagct tcagcagcaa
    82321 cgatgtatgt gacagataag gacaatacct caagcaaggt tcacctgaac aatgtttctg
    82381 atacatttga agtaacagta acagttcaca acaaatctga taaacctcaa gagttgtatt
    82441 accaagcaac tgttcaaaca gataaagtag atggaaaaca ctttgccttg gctcctaaag
    82501 cattgtatga gacatcatgg caaaaaatca caattccagc caatagcagc aaacaagtca
    82561 ccgttccaat cgatgctagt cgatttagca aggacttgct tgcccaaatg aaaaatggct
    82621 atttcttaga aggttttgtt cgtttcaaac aagatcctac aaaagaagag cttatgagca
    82681 ttccatatat tggtttccga ggtgattttg gcaatctgtc agccttagaa aaaccaatct
    82741 atgatagcaa agatggtagc agctactatc atgaagcaaa tagtgatgcc aaagaccaat
    82801 tagatggtga tggattacag ttttacgctc tgaaaaacaa ctttacagca cttaccacag
    82861 agtctaaccc atggacgatt attaaagctg tcaaagaagg ggttgaaaac atagaggata
    82921 tcgaatcttc agagatcaca gaaaccattt ttgcaggtac ttttgcaaaa caagacgatg
    82981 atagccacta ctatatccac cgtcacgcta atggcaaacc atatgctgcg atctctccaa
    83041 atggggacgg taacagagat tatgtccaat tccaaggtac tttcttgcgt aatgctaaaa
    83101 accttgtggc tgaagtcttg gacaaagaag gaaatgttgt ttggacaagt gaggtaaccg
    83161 agcaggttgt taaaaactac aacaatgact tggcaagcac acttggttca acccgttttg
    83221 aaaaaacgcg ttgggacggt aaagataaag acggcaaagt tgttgctaac ggaacctaca
    83281 cctatcgtgt ccgctacact ccgattagct caggtgcaaa agaacaacac actgattttg
    83341 atgtgattgt agacaatacg acacctgaag tcgcaacatc ggcaacattc tcaacagaag
    83401 atcgtcgttt gacacttgca tctaaaccaa aaaccagcca accggtttac cgtgagcgta
    83461 ttgcttacac ttatatggat gaggatctgc caacaacaga gtatatttct ccaaatgaag
    83521 atggtacctt tactcttcct gaagaggctg aaacaatgga aggcgctact gttccattga
    83581 aaatgtcaga ctttacttat gttgttgaag atatggctgg taacatcact tatacaccag
    83641 tgactaagct attggagggc cactctaata agccagaaca agacggttca gatcaagcac
    83701 cagacaaaaa accagaaact aaaccagaac aagacggttc aggtcaagca ccagacaaaa
    83761 aaccagaagc taaaccagaa caagacggtt caggtcaaac accagataaa aaaccagaag
    83821 ctaaaccaga acaagacggt tcaggtcaaa caccagataa aaaaccagaa actaaaccag
    83881 aaaaagatag ttcaggtcaa acaccaggta aaactcctca aaaaggtcaa ccttctcgta
    83941 ctctagagaa acgatcttct aagcgtgctt tagctacaaa agcatcaaca agagatcagt
    84001 taccaacgac taatgacaag gatacaaatc gtttacatct ccttaagtta gttatgacca
    84061 ctttcttctt gggattagta gctcatatct ttaaaacaaa acgcactgaa gattagtaca
    84121 actgatcaga tggctactat tgatgatgag ttagatcagt cttcttttca aaagaaggca
    84181 tagcagtata aaaatagata tgtgaggaca atatgcttag agcagaaaat aacaaacaca
    84241 gccgctattc tattcgcaag ctgagcgttg gggtaacgag tatagcaatt gcgagtctct
    84301 ttttaggaaa ggttgcctat gccgtagata gcatgcagca aaactcttcg actcaaagaa
    84361 acacagccaa tacatccaaa aaatggtatc atattgatga taggggcttt attcctttag
    84421 gtataagctt agaagctgcc aaaaaagatt ttaaagaaga agtagaaaaa tcacgtttgt
    84481 ctgaagaaca aaaacaaacg tataatcaaa aaattgatgc tgaaacagac aaagacgaac
    84541 tattgtcaac gtatcataga gactatctga cagccgttaa gaatcttcca acgtctactg
    84601 agccagttga ggcacccgtg caggagacac aggcataagt ttcagattcg atggtgacag
    84661 gtgattcaac atcagttacg actgattctc ctgaggaaac actatctaca gaaaccccat
    84721 ctccatcacc tgagagtgag aaatcttcag tagcagcttc ttctgaggaa acctcatctc
    84781 cagaaactcc atcaactcca gaggccccag tagccccagc tttatctgag gctccatctc
    84841 catcacctga gagtgaggaa ccttcagtag cagcttcttc tgaggaaacc ccatctccat
    84901 caactccagc agccccagaa actccagcgg ctccagaaac tccagcggct ccagaaactc
    84961 ctgaggaacc ttcagtagca gctccttctg aggaaacccc atctccatca actccagcag
    85021 ccccagaaat cccagctgaa tcagaggctc cagctcaacc agctgagagt gaagaatctt
    85081 cagtagcagc tacgacaagt ccgtctccat caactccagc tgaatcagag actcagacgc
    85141 catcagctgt tactaaagac tctgataagc catcttcagc agctgaaaaa ccagcagcct
    85201 cttcacttgt ttcagaacaa accgttcaac aaccaacttc aaagagatct tctgataaaa
    85261 aagaagagca agaacagtct tactctccaa atcgctcatt gtcaagacag gttatggccc
    85321 atgagtcagg taagtacttg ccttcaacag gtgaaaaagc acagccactc tttatagcta
    85381 ctatgacttt gatgtctcta tttggcagtc ttttagtcac aaaacgccaa aaagaaacta
    85441 aaaaatagta ttacttaaac tgataagagc ttatttaata gagagaacca atttggttct
    85501 ctctattttt ttagatgtgc agcctcatca aaaagaagtt aggacaaata gctgtcaaca
    85561 attgcctttt gcttatccct tcagttgctg tgattttatc atacagtgat aaaagatggt
    85621 agttgccatt gacaaagcat tgataaagga gtaaaattaa ctggttaata actggttaaa
    85681 ttataattga ggaggtacta tgaaaaaagg tttttttctc atggctatgg ctgtgagttt
    85741 agtaatgata gcagggtgtg ataagtcagc aaaccccaaa cagcctacgc aaggcatgtc
    85801 agttgtaacc agcttttacc caatgtatgc gatgacaaaa gaagtatctg gagacctcaa
    85861 tgatgtgagg atgatccaat caggtgcagg cattcattcc tttgaaccgt ctgtaaatga
    85921 tgtggcagct atttatgacg cggatttgtt tgtttaccat tcacatacct tagaagcttg
    85981 ggcaagggat ctagacccta atttaaaaaa atcaaaggtt gatgtgtttg aagcgtcaaa
    86041 acctctgaca ctagatagag tcaaagggct agaagatatg gaagtcacac aaggcattga
    86101 ccctgcgaca ctttatgacc cacatacctg gacagatccc gttttagctg gtgaggaagc
    86161 tgtcaatatc gctaaagagc taggacgttt ggatcctaaa cacaaagaca gttacactaa
    86221 aaaggctaag gctttcaaaa aagaagcaga gcaactaact gaagaataca ctcaaaaatt
    86281 taaaaaggtg cgctcaaaaa catttgtgac gcaacacacg gcattttctt atctggctaa
    86341 acgattcggc ttgaaacaac ttggtatctc gggtatttct ccagagcaag agccctctcc
    86401 tcgccaattg aaagaaattc aagactttgt caaagaatac aacgtcaaga ctatttttgc
    86461 agaagacaat gtcaatccca aaattgctca tgctattgcg aaatcaacag gagctaaagt
    86521 aaagacatta agtccacttg aagctgctcc aagcggaaac aagacatatc tagaaaatct
    86581 tagagcaaat ttggaagtgc tctatcaaca gttgaagtaa aggagattat tagtgaagaa
    86641 aacatatggt tatatcggct cagttgctgc cattttacta gctactcata ttggaagtta
    86701 ccaacttggt aagcatcata tgggtccagc aacaaaggac aatcagattg cctatattga
    86761 tgatagcaaa ggtaaggcaa aagcccctaa aacaaacaaa acgatggatc aaatcagtgc
    86821 tgaagaaggc atctctgctg aacagatcgt agtcaaaatt actgaccaag gttatgtgac
    86881 ctcacacggt gaccattatc atttttacaa tgggaaagtt ccttatgatg cgattattag
    86941 tgaagagttg ttgatgacgg atcctaatta ccgttttaaa caatcagacg ttatcaatga
    87001 aatcttagac ggttacgtta ttaaagtcaa tggcaactat tatgtttacc tcaagccagg
    87061 tagcaagcgc aaaaacattc gaaccaaaca acaaattgct gagcaagtag ccaaaggaac
    87121 taaagaagct aaagaaaaag gtttagctca agtggcccat ctcagtaaag aagaagttgc
    87181 ggcagtcaat gaagcaaaaa gacaaggacg ctatactaca gacgatggct atatttttag
    87241 tccgacagat atcattgatg atttaggaga tgcttattta gtacctcatg gtaatcacta
    87301 tcattatatt cctaaaaaag atttgtctcc aagtgagcta gctgctgcac aagcctactg
    87361 gagtcaaaaa caaggacgag gtgctagacc gtctgattac cgcccgacac cagccccagg
    87421 tcgtaggaaa gccccaattc ctgatgtgac gcctaaccct ggacaaggtc atcagccaga
    87481 taacggtggc tatcatccag cgcctcctag gccaaatgat gcgtcacaaa acaaacacca
    87541 aagagatgag tttaaaggaa aaacctttaa ggaactttta gatcaactac accgtcttga
    87601 tttgaaatac cgtcatgtgg aagaagatgg gttgattttt gaaccgactc aagtgatcaa
    87661 atcaaacgct tttgggtatg tggtgcctca tggagatcat tatcatatta tcccaagaag
    87721 tcagttatca cctcttgaaa tggaattagc agatcgatac ttagccggcc aaactgagga
    87781 caatgactca ggttcagatc actcaaaacc atcagataaa gaagtgacac atacctttct
    87841 tggtcatcgc atcaaagctt acggaaaagg cttagatggt aaaccatatg atacgagtga
    87901 tgcttatgtt tttagtaaag aatccattca ttcagtagat aaatcaggag ttacagctaa
    87961 acacggagat catttccact atataggatt tggagaactt gaacaatatg agttggatga
    88021 ggtcgctaac tgggtgaaag caaaaggcca agctgatgag cttgctgctg ctttggatca
    88081 ggaacaaggc aaagaaaaac cactctttga cactaaaaaa gtgagtcgca aagtaacaaa
    88141 agatggtaaa gtgggctata tgatgtcaaa agatggcaag gactatttct atgctcgtga
    88201 tcaacttgat ttgactcaga ttgcctttgc cgaacaagaa ctaatgctta aagataagaa
    88261 gcattaccgt tatgacattg ttgacacagg tattgagcca cgacttgctg tagatgtgtc
    88321 aagtctgccg atgcatgctg gtaatgctac ttacgatact ggaagttcgt ttgttatccc
    88381 tcatattgat catatccatg tcgttccgta ttcatggttg acgcgtgatc agattgcaac
    88441 aatcaagtat gtgatgcaac accccgaagt tcgtccggat gtatggtcta agccagggca
    88501 tgaagagtca ggttcggtca ttccaaatgt tacgcctctt gataaacgtg ctggtatgcc
    88561 aaattggcaa attatccatt ctgctgaaga agttcaaaaa gccctagcag aaggtcgttt
    88621 tgcaacacca gacggctata ttttcgatcc acgagatgtt ttggccaaag aaacttttgt
    88681 atggaaagat ggctccttta gcatcccaag agcagatggc agttcattga gaaccattaa
    88741 taaatctgat ctatcccaag ctgagtggca acaagctcaa gagttattgg caaagaaaaa
    88801 cgctggtgat gctactgata cggataaacc caaagaaaag caacaggcag ataagagcaa
    88861 tgaaaaccaa cagccaagtg aagccagtaa agaagaagaa aaagaatcag atgactttat
    88921 agacagttta ccagactatg gtctagatag agcaacccta gaagatcata tcaatcaatt
    88981 agcacaaaaa gctaatatcg atcctaagta tctcattttc caaccagaag gtgtccaatt
    89041 ttataataaa aatggtgaat tggtaactta tgatatcaag acacttcaac aaataaaccc
    89101 ttaaccaaaa gaagatctca ttattaaagc actgctttat caaagcaagt tacggtgatt
    89161 ttgaagtcat tttatgtaac gagtagtgat aaaagttgga taatagcggt tttcttttgc
    89221 aaagaaatgg tatccatgtt agaataataa aaaaaagagg aggattctaa tcatgtcaga
    89281 agaaaaatta aaatcaaaaa ttgagcaagc atctggtggc ctaaaagaag gtgctggtaa
    89341 gttgacaggt gataaagagc tagaagcaaa aggatttgtt gaaaaaacaa ttgctaaagg
    89401 caaagaactt gcagacgatg caaaagaagc ggttgaaggt gctgtagatg ccgttaagga
    89461 aaaattaaaa taattaaaaa accagctgta agctggtttt ttaatggtgt gattttgtta
    89521 gaaaaagact caataggtaa taaccataga tgttaggtat gcttgaacag ttgagtacga
    89581 ttctcttcaa tcatatagca cgcgtcacaa agtttttcta acatatcaaa atcatgacta
    89641 ataatgatga gacctaaatt tctatccttt acaatctcca acaggctttt ccatacacta
    89701 gcttgtgtaa tgctatccaa catagtagtc atttcatctg caataaggta tttcgtctct
    89761 ggatgtaatg aacgcacaat cgaaaagcgt tgcaattccc ctcccgagag ttcactaggg
    89821 cgacgcttta gccatttttc ttgaatgcca aaagcatctc gcaaatcttg acttggatag
    89881 taggcttctt ccaaactttt tttcataggc cataaaggat tcatggtttg ttcaggatgt
    89941 tgttggataa gttgcacagg tctaaatgct ttgttaggca aatgactgcc atcaactaat
    90001 acttcaccag atttaggctg caaaaaaccg gcaagcactc tggataaact cgtttttcca
    90061 cacccacttt gtccaaatat ccctaagatt tgaccaggtg ctacctctaa atcaatctcc
    90121 ttaaaaagcc attgatcttt tttatgataa aagccaagct ttttagcctc taaggtcatg
    90181 agtaactcct ttcaaaaagt cttgctgagg gagtgtgcgc cataaacgtc tcgcaaattc
    90241 tgtttgtaat tgctccccac ctccgctaaa aaagctagct ggggctgttt caatagcttt
    90301 tccctcttta aaaatagtta tacgatccgc aatttgacta gctgctacaa tatcatgagt
    90361 gataaagatg acgcttattc ctttatctgc aaaagagcgt agttgatcta aaaccatttg
    90421 cagagcatct ggatgtaatc caggggtggg ctcatccgca ataatcaaag aaaccgtatc
    90481 actaatacac gttgtaaaca aaacacgtcg gagcattccg ccagaaagtt ggaaaggata
    90541 caagtcacca tcactttctt ttaaaccaaa ctgttgaaat aatccttctt gagtagcctt
    90601 agcattttct gagataccca agcgcacctg atgcttgact ttcatagatg gatctaaata
    90661 attaacggat tgtggaatca acgtcatttc ttttcctcgc aactgtttaa tgcgtttaga
    90721 agttagtgat tgaccacgat aaatcatatc tcctgttaca gctgcatttt taggaagaat
    90781 atccataata gcgtgtgcta ataaactctt ccctgaacca ctagcaccta taatagctaa
    90841 caactcacct tttttaactt ctaaattcag cgcttgtatc ggtgtggatt gaaatggttt
    90901 taaaaatctt ccgtattgag tgaaggtgat ggagaggtct ttaatgctta ataatgtttc
    90961 tgtcatatct ctacctccta aaaatgatcc gtttgagggt aaaagagttt ctttaaagat
    91021 tctccgatag tatcaaatgc attgacaacc aaaataagat aaaggcctgg aaaaatcacc
    91081 aaccaccaat tgccaagaga gatatgctta gctgcctctg ataaaatgat accaaccgaa
    91141 ggttgttcgg cagaaaggcc aaatcctaag aaagtcatgg atgcttcatg caagatgacg
    91201 tgcggaaata agaggataaa cccaatgaaa atttgagaag caatcaaagg caagatatga
    91261 tgcctcacaa tataataagg cgtttttccc atgcttttag agagctggac aaaggcttta
    91321 ttctttagat catagacttc attgcggata agccttgcta gagagggcca atgggtaaca
    91381 gctgttgcaa tgataacccc ttgagcccct ttcccaacaa caaaagaaat gagaatcata
    91441 aaaatcaaat gaggcatacc aataaacaaa tcaaccaacc aggctattat tttatcaata
    91501 aggctatttc ctagacctgc aagcactcca aaaacggtcg caagaaagac tcccataagg
    91561 gcacctaata agccgacttg taaagagaaa taaagccctt taatcgttct gacaaacata
    91621 tccctaccta aaccatctgt cccaaaaaga tggtttaagg aaggagcaag gttgcgtaaa
    91681 gctgcattgg tttccaaagg cgtcctatag aaataaaggt ttaaggctag aatactaaga
    91741 atgagagaaa tggcgatacc cagttgccat aaaaccatcg ttcgacgttt caatatcata
    91801 cttttctcct taactgtgga ttgatgatgc tatttaaaat gtccgcaata aaattgcccg
    91861 caaaaacaaa taatgtccct atcatcacaa tagctagaag tagcggtgta tcacttttaa
    91921 ggcctgcttc agtgagggta gaccctaagc caggatatga gaaaacttgc tcagcaagaa
    91981 cagatcctcc aaacaactct ccaaaatagg aaaaatgcag tgtaatagct ggtacgatag
    92041 catttctaag acaatgatgt ttaaaaattt gccactgtgt ttccccacgc gctctggcaa
    92101 ataagacata ttcactagaa agcaccgaca tcattttagt tctcgtatga agagtgacat
    92161 tggcgatgcc tagaatactt agcgtgaaaa caggtaacat aaggtgctta atccgatcag
    92221 ctaacgtaat atcttgactc aaagtgccta tcggagaaga aataccaatc gggaaccacc
    92281 ccagctggac agaaaagatt aataaaaaaa tgagtccaat ccaaaacgtt ggtactgata
    92341 tctgaaggta tgaaaaccac ctgataactc ggtcaagtaa tttcccttga tggaaagcgg
    92401 ataacgttcc taagataaat ccaataagac ccgataagat ccaagagagt cccataagta
    92461 tgaaagaagc acctgcccgt gatctaataa tatcactaac aggttgccga taaacgagcg
    92521 aggtccctaa atgtccctgt atcacatttt tcaaccaaat aaaatactgg actagagctg
    92581 gcttatccaa gccatagtgg tgagcaatcg ctttgtactg agcaggggtt agtgatgtgt
    92641 cataattgac acttgccatg actggatcta ctggagattg ttttaacaaa acgaaggtca
    92701 aaacagatac cccaaaaata agcgtgacac atctgatgat tttccagatg ataataatgg
    92761 tagtacgttt cacaatgaaa tctccttaat cgataagaaa aggagccgag gaaacgatca
    92821 gcacagtttt gtgtatcttg ttttctcaga ctccaaactt aaagtcgctg tattaactaa
    92881 acgcgttact tagttgattc atcccaagtc cactcggcaa tgttagtcaa taatgaccaa
    92941 tcatgaccat gactgtggat gccttgttta cctacattga tacgtttatc accaatataa
    93001 gtatggttaa ggctcaccaa ccatacattt ggcaaatctc caagagtaga agcacctgtt
    93061 ttgccatccc actgcgctaa cttccaatat tcgttagctt tgtcaaggtc agaagatgtc
    93121 attgctttgt caaggtactt agtcacggta ggattgttat aaaacgtaat attggtccaa
    93181 cctttacctg ctaggcttgg atgatgtgat tcataaaatt gctgcgcgtg atgacgtcct
    93241 ccggcataaa gtaaggctga gtcatgtgac ttcgttgcca tttcatccca gttactagct
    93301 ttgagtttaa tagtaatccc tagggctttg gcttgctctg ctacttcaac ggctaagttc
    93361 gctcgcaatt gatcattagt agggtagtac agatcaaacg ctgcatcaag gtcacctttt
    93421 ttacggctac cgtctgcttg ttctttccat cccgcttttg tcaacaattg cttagcttta
    93481 gctactttat tatctttaat ggctgttttt ggattccaaa atggtgtttt atcaataatt
    93541 gaataagctg gtttaccata accatttaaa accgtatcga gaactttttg cctatttaaa
    93601 ccaatagtca aggctttgcg gattgctgga tcactagtga catcatttcc tacaggataa
    93661 ccatcaggag aatcagtgat gacgcctttt ttcacataag gtaatgataa gccgcgcaca
    93721 tcatttgatg gaatatcaag gaggcgggtg cctttgactt ttttatcagc aagttctggt
    93781 gtcgcgtaga tcatatcaac atcaccagat tctaaagctg ctagtgctgt gttttcatca
    93841 agtaagaccc aagtccactt tttaaagtat ggttttttcc catgccagta agggttacga
    93901 acaaaaatag cttgttctcc agccttatat tcttttacca tgtaaggtcc tgaaccgata
    93961 ggattgctct tatacttatc attgtaatgt tttttaggga cgattgggat ttcagtcaac
    94021 tgtgctgtaa atgtcgaatg cgcctcagtc aaatggatat tgacctgatt tttcccaact
    94081 acttcaacgt tcttgatgaa ggttagatcc caagcctttc catctgcttt caacatatca
    94141 taagtaaact taacatcatc agcagtaaca ggctcaccat ttgagaattt aaaatcatca
    94201 tgcaagtcaa acgaccaagt cagcccatct tcagagagat ggtatgtttt agcaagctct
    94261 ccttttatat ctagttcagg agaacgtttc aatagagtgc tatgagtgat attcccttca
    94321 ttgtggactc cataacggtc ctttggatcg aattcatgag ggagctttgc ccccatagaa
    94381 acgacaagtt cgtcttttgg acgttgtttg cgctgacgtt cttttgtttg aggcttttgt
    94441 tgttgacatg caactaaaat aagcccagtc aaaaataacg tgataataga gaagtatttt
    94501 aggtattttg acacaatcaa atctccttat tt
//
LOCUS       DAUGOH010000002        86611 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUGOH010000002 DAUGOH010000000
VERSION     DAUGOH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 86611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86611
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.002"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            26..928
                     /locus_tag="VH957_000076"
     CDS             26..928
                     /locus_tag="VH957_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8558029.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSNISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            941..1645
                     /locus_tag="VH957_000077"
     CDS             941..1645
                     /locus_tag="VH957_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558030.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(1994..2959)
                     /locus_tag="VH957_000078"
     CDS             complement(1994..2959)
                     /locus_tag="VH957_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEQ8558031.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            3031..4419
                     /locus_tag="VH957_000079"
     CDS             3031..4419
                     /locus_tag="VH957_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8558032.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGVAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDVEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            complement(4542..4994)
                     /locus_tag="VH957_000080"
     CDS             complement(4542..4994)
                     /locus_tag="VH957_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEQ8558033.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            5225..6439
                     /locus_tag="VH957_000081"
     CDS             5225..6439
                     /locus_tag="VH957_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8558034.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            6656..7438
                     /gene="codY"
                     /locus_tag="VH957_000082"
     CDS             6656..7438
                     /gene="codY"
                     /locus_tag="VH957_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEQ8558035.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDDEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            7585..8139
                     /locus_tag="VH957_000083"
     CDS             7585..8139
                     /locus_tag="VH957_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEQ8558036.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            8583..8901
                     /locus_tag="VH957_000084"
                     /pseudo
     CDS             8583..8901
                     /locus_tag="VH957_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991537.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
     gene            9133..9435
                     /gene="gatC"
                     /locus_tag="VH957_000085"
     CDS             9133..9435
                     /gene="gatC"
                     /locus_tag="VH957_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEQ8558037.1"
                     /translation="MKISEEEARHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDIAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            9435..10901
                     /gene="gatA"
                     /locus_tag="VH957_000086"
     CDS             9435..10901
                     /gene="gatA"
                     /locus_tag="VH957_000086"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEQ8558038.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            10901..12340
                     /gene="gatB"
                     /locus_tag="VH957_000087"
     CDS             10901..12340
                     /gene="gatB"
                     /locus_tag="VH957_000087"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEQ8558039.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGAIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            12337..12552
                     /locus_tag="VH957_000088"
     CDS             12337..12552
                     /locus_tag="VH957_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558040.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTAYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNHHVCPHYY"
     gene            12771..13010
                     /locus_tag="VH957_000089"
     CDS             12771..13010
                     /locus_tag="VH957_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8558041.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIITGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            13402..14109
                     /locus_tag="VH957_000090"
     CDS             13402..14109
                     /locus_tag="VH957_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8558042.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            14099..14842
                     /locus_tag="VH957_000091"
     CDS             14099..14842
                     /locus_tag="VH957_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEQ8558043.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDSQEHLISGYRSVDYQTELYQSSIKKEMANDPTLTQEAAEALVQTYSQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            14839..15408
                     /locus_tag="VH957_000092"
     CDS             14839..15408
                     /locus_tag="VH957_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8558044.1"
                     /translation="MRKRLKFPYFLTLLACFLLLLVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            15543..16577
                     /gene="hrcA"
                     /locus_tag="VH957_000093"
     CDS             15543..16577
                     /gene="hrcA"
                     /locus_tag="VH957_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEQ8558045.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            16580..17152
                     /gene="grpE"
                     /locus_tag="VH957_000094"
     CDS             16580..17152
                     /gene="grpE"
                     /locus_tag="VH957_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEQ8558046.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            17333..19159
                     /gene="dnaK"
                     /locus_tag="VH957_000095"
     CDS             17333..19159
                     /gene="dnaK"
                     /locus_tag="VH957_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEQ8558047.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            19440..20576
                     /gene="dnaJ"
                     /locus_tag="VH957_000096"
     CDS             19440..20576
                     /gene="dnaJ"
                     /locus_tag="VH957_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEQ8558048.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            20796..21587
                     /locus_tag="VH957_000097"
     CDS             20796..21587
                     /locus_tag="VH957_000097"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEQ8558049.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            21661..22095
                     /locus_tag="VH957_000098"
     CDS             21661..22095
                     /locus_tag="VH957_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8558050.1"
                     /translation="MEYDKINHYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            22096..23070
                     /locus_tag="VH957_000099"
     CDS             22096..23070
                     /locus_tag="VH957_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEQ8558051.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLANIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVRI"
     gene            23131..23355
                     /locus_tag="VH957_000100"
     CDS             23131..23355
                     /locus_tag="VH957_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8558052.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            23557..24528
                     /gene="fabK"
                     /locus_tag="VH957_000101"
     CDS             23557..24528
                     /gene="fabK"
                     /locus_tag="VH957_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEQ8558053.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            24553..25491
                     /gene="fabD"
                     /locus_tag="VH957_000102"
     CDS             24553..25491
                     /gene="fabD"
                     /locus_tag="VH957_000102"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEQ8558054.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            25481..26215
                     /gene="fabG"
                     /locus_tag="VH957_000103"
     CDS             25481..26215
                     /gene="fabG"
                     /locus_tag="VH957_000103"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEQ8558055.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            26230..27462
                     /gene="fabF"
                     /locus_tag="VH957_000104"
     CDS             26230..27462
                     /gene="fabF"
                     /locus_tag="VH957_000104"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEQ8558056.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            27464..27964
                     /locus_tag="VH957_000105"
     CDS             27464..27964
                     /locus_tag="VH957_000105"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEQ8558057.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            27961..28383
                     /gene="fabZ"
                     /locus_tag="VH957_000106"
     CDS             27961..28383
                     /gene="fabZ"
                     /locus_tag="VH957_000106"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEQ8558058.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            28415..29779
                     /locus_tag="VH957_000107"
     CDS             28415..29779
                     /locus_tag="VH957_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEQ8558059.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRHNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            29788..30654
                     /locus_tag="VH957_000108"
     CDS             29788..30654
                     /locus_tag="VH957_000108"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEQ8558060.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            30651..31421
                     /locus_tag="VH957_000109"
     CDS             30651..31421
                     /locus_tag="VH957_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEQ8558061.1"
                     /translation="MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYKRFRKY"
     gene            complement(31644..32921)
                     /gene="serS"
                     /locus_tag="VH957_000110"
     CDS             complement(31644..32921)
                     /gene="serS"
                     /locus_tag="VH957_000110"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEQ8558062.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(33313..33672)
                     /locus_tag="VH957_000111"
     CDS             complement(33313..33672)
                     /locus_tag="VH957_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEQ8558063.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            complement(33786..34697)
                     /locus_tag="VH957_000112"
     CDS             complement(33786..34697)
                     /locus_tag="VH957_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8558064.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            complement(34714..35523)
                     /locus_tag="VH957_000113"
     CDS             complement(34714..35523)
                     /locus_tag="VH957_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEQ8558065.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGIIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            complement(35612..36604)
                     /gene="manX"
                     /locus_tag="VH957_000114"
     CDS             complement(35612..36604)
                     /gene="manX"
                     /locus_tag="VH957_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEQ8558066.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            complement(36956..37768)
                     /locus_tag="VH957_000115"
     CDS             complement(36956..37768)
                     /locus_tag="VH957_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8558067.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            38031..39491
                     /locus_tag="VH957_000116"
     CDS             38031..39491
                     /locus_tag="VH957_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEQ8558068.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSGVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDMSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIIVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            39645..40106
                     /gene="tsaE"
                     /locus_tag="VH957_000117"
     CDS             39645..40106
                     /gene="tsaE"
                     /locus_tag="VH957_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEQ8558069.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHGSAKSRY"
     gene            40081..40605
                     /locus_tag="VH957_000118"
     CDS             40081..40605
                     /locus_tag="VH957_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8558070.1"
                     /translation="MVQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSGFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            40614..41897
                     /locus_tag="VH957_000119"
     CDS             40614..41897
                     /locus_tag="VH957_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8558071.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     KLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDYTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(42008..42364)
                     /locus_tag="VH957_000120"
     CDS             complement(42008..42364)
                     /locus_tag="VH957_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ8558072.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISRDLAHKWRYFNQETQAHLTEIQNRMAKYQENSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(42361..42780)
                     /locus_tag="VH957_000121"
     CDS             complement(42361..42780)
                     /locus_tag="VH957_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8558073.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            42852..43577
                     /locus_tag="VH957_000122"
     CDS             42852..43577
                     /locus_tag="VH957_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558074.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            43580..44614
                     /locus_tag="VH957_000123"
     CDS             43580..44614
                     /locus_tag="VH957_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558075.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISIKVKERAYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNMLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            44678..45469
                     /locus_tag="VH957_000124"
     CDS             44678..45469
                     /locus_tag="VH957_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEQ8558076.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            45469..46104
                     /gene="trmB"
                     /locus_tag="VH957_000125"
     CDS             45469..46104
                     /gene="trmB"
                     /locus_tag="VH957_000125"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEQ8558077.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFFNKGQVIYRVEANF"
     gene            46169..46255
                     /locus_tag="VH957_000126"
     tRNA            46169..46255
                     /locus_tag="VH957_000126"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46203..46205,aa:Ser,seq:gga)
     gene            46363..46899
                     /gene="rimP"
                     /locus_tag="VH957_000127"
     CDS             46363..46899
                     /gene="rimP"
                     /locus_tag="VH957_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEQ8558078.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            47074..48231
                     /gene="nusA"
                     /locus_tag="VH957_000128"
     CDS             47074..48231
                     /gene="nusA"
                     /locus_tag="VH957_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEQ8558079.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV"
     gene            48247..48543
                     /locus_tag="VH957_000129"
     CDS             48247..48543
                     /locus_tag="VH957_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEQ8558080.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            48536..48838
                     /locus_tag="VH957_000130"
     CDS             48536..48838
                     /locus_tag="VH957_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEQ8558081.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAVADAGFSKKMRTLME"
     gene            48858..51719
                     /gene="infB"
                     /locus_tag="VH957_000131"
     CDS             48858..51719
                     /gene="infB"
                     /locus_tag="VH957_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEQ8558082.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            51925..52275
                     /gene="rbfA"
                     /locus_tag="VH957_000132"
     CDS             51925..52275
                     /gene="rbfA"
                     /locus_tag="VH957_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEQ8558083.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELDKKD"
     gene            complement(52328..53329)
                     /locus_tag="VH957_000133"
     CDS             complement(52328..53329)
                     /locus_tag="VH957_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8558084.1"
                     /translation="MKKTLKSTLILLGLTLAIGASTQVDASSRSWKSWFIEKYFWLKG
                     DKGYYSEQDETKFDQYVNSAGEASNKGFDLKEEQVNGTLVTKTVDNMQVHTWNENPSN
                     KANQKVIFYLHGGSYLNNPTTYHIDMLKTLSTSLDAKIILPIYPKAPTYSYSDAMPKL
                     VDLYRDTLKETTAQNITIMGDSAGGGLALGLALALKNESLKQPKDIVLLSPWLDVTMS
                     NPDIESYESNDPILSAWGLRKVGEIWARRDPNNTKHPYVSPINGDVSGLAPITMFVGT
                     HEIFYPDVKKFDDILTAKGHQHELIVADKMNHVYPIYPIEEAKTAQYQIIDTIQKAY"
     gene            53492..53929
                     /locus_tag="VH957_000134"
     CDS             53492..53929
                     /locus_tag="VH957_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEQ8558085.1"
                     /translation="MNQNISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKT
                     LIGRLVEKKALGTYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLYD
                     LPMTLEEIEAFQELLEVKKENAVLEVPCNCLPGQCHCQKKETY"
     gene            53929..56160
                     /locus_tag="VH957_000135"
     CDS             53929..56160
                     /locus_tag="VH957_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEQ8558086.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPSFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGRAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTYQAIQKLLSLKATDVRVWRNSQWQLLPLEEISYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGQGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGVLFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQNLLT
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNATLMATLGIDLASVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALQQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVITNLQSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            56174..56377
                     /locus_tag="VH957_000136"
     CDS             56174..56377
                     /locus_tag="VH957_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEQ8558087.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLLKRALKDTKFELHKWS"
     gene            complement(56581..57351)
                     /locus_tag="VH957_000137"
     CDS             complement(56581..57351)
                     /locus_tag="VH957_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8558088.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQSTQLLVAHENKE"
     gene            57588..58061
                     /locus_tag="VH957_000138"
     CDS             57588..58061
                     /locus_tag="VH957_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8558089.1"
                     /translation="MFPNILFTEARTQPEFFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTMILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            58054..58359
                     /locus_tag="VH957_000139"
     CDS             58054..58359
                     /locus_tag="VH957_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8558090.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPIVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            58385..59836
                     /locus_tag="VH957_000140"
     CDS             58385..59836
                     /locus_tag="VH957_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEQ8558091.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHNHLPVLVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIVSI
                     ITLIIFIAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            60094..60519
                     /gene="lacA"
                     /locus_tag="VH957_000141"
     CDS             60094..60519
                     /gene="lacA"
                     /locus_tag="VH957_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8558092.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            60534..61049
                     /gene="lacB"
                     /locus_tag="VH957_000142"
     CDS             60534..61049
                     /gene="lacB"
                     /locus_tag="VH957_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8558093.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLETHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            61059..61512
                     /locus_tag="VH957_000143"
                     /pseudo
     CDS             61059..61512
                     /locus_tag="VH957_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            61559..62536
                     /gene="lacD"
                     /locus_tag="VH957_000144"
     CDS             61559..62536
                     /gene="lacD"
                     /locus_tag="VH957_000144"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8558094.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            62733..63350
                     /locus_tag="VH957_000145"
     CDS             62733..63350
                     /locus_tag="VH957_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEQ8558095.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEKR"
     gene            63352..64176
                     /locus_tag="VH957_000146"
     CDS             63352..64176
                     /locus_tag="VH957_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8558096.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLDLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPRGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(64213..64770)
                     /locus_tag="VH957_000147"
     CDS             complement(64213..64770)
                     /locus_tag="VH957_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8558097.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLKTKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            65063..65905
                     /locus_tag="VH957_000148"
     CDS             65063..65905
                     /locus_tag="VH957_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8558098.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            complement(66034..66756)
                     /locus_tag="VH957_000149"
     CDS             complement(66034..66756)
                     /locus_tag="VH957_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558099.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            66958..68589
                     /locus_tag="VH957_000150"
     CDS             66958..68589
                     /locus_tag="VH957_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEQ8558100.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADGKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            68707..69855
                     /gene="nagA"
                     /locus_tag="VH957_000151"
     CDS             68707..69855
                     /gene="nagA"
                     /locus_tag="VH957_000151"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEQ8558101.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWIEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            69977..70816
                     /locus_tag="VH957_000152"
     CDS             69977..70816
                     /locus_tag="VH957_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEQ8558102.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDHLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSATPNPDT
                     TSF"
     gene            70948..71481
                     /locus_tag="VH957_000153"
     CDS             70948..71481
                     /locus_tag="VH957_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEQ8558103.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            71853..72770
                     /gene="glyQ"
                     /locus_tag="VH957_000154"
     CDS             71853..72770
                     /gene="glyQ"
                     /locus_tag="VH957_000154"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8558104.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            73148..75187
                     /locus_tag="VH957_000155"
     CDS             73148..75187
                     /locus_tag="VH957_000155"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEQ8558105.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPAH
                     TLTVLLDDEALDLDFLDIHSGRVSRGHRFLGKETTITSADSYEDDLRSQFVIADAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGNFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYARLAGEDAAVARAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYANKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAVAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAVIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQALKNNRLAILSDLVSKAKTIAAFNQLNTK"
     gene            75341..75598
                     /locus_tag="VH957_000156"
     CDS             75341..75598
                     /locus_tag="VH957_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEQ8558106.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            75725..76117
                     /locus_tag="VH957_000157"
     CDS             75725..76117
                     /locus_tag="VH957_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEQ8558107.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            76477..78003
                     /gene="glpK"
                     /locus_tag="VH957_000158"
     CDS             76477..78003
                     /gene="glpK"
                     /locus_tag="VH957_000158"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEQ8558108.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            78019..79857
                     /gene="glpO"
                     /locus_tag="VH957_000159"
     CDS             78019..79857
                     /gene="glpO"
                     /locus_tag="VH957_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEQ8558109.1"
                     /translation="MEFSKETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGHQEG"
     gene            79859..80560
                     /locus_tag="VH957_000160"
     CDS             79859..80560
                     /locus_tag="VH957_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8558110.1"
                     /translation="MDIFGEFLGTVLLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAYLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            80669..82015
                     /locus_tag="VH957_000161"
     CDS             80669..82015
                     /locus_tag="VH957_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8558111.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRIIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QVNIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDADLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            82005..83504
                     /locus_tag="VH957_000162"
     CDS             82005..83504
                     /locus_tag="VH957_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8558112.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHKHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGVILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMDQETDFSQQLSDDILALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            83630..84274
                     /gene="fsa"
                     /locus_tag="VH957_000163"
     CDS             83630..84274
                     /gene="fsa"
                     /locus_tag="VH957_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8558113.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMMQHPLTTNGLKTFMEDWASFKK"
     gene            84492..86477
                     /gene="tkt"
                     /locus_tag="VH957_000164"
     CDS             84492..86477
                     /gene="tkt"
                     /locus_tag="VH957_000164"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEQ8558114.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QEALEAEDIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
BASE COUNT        26382 a        15388 c        18812 g        26029 t
ORIGIN      
        1 gataagtaca aaaaaggagc ggaaaatgac acagcaatca atgttactaa gtattgagca
       61 agtaaataaa tcctatggta aaaatcaggt tttaagtaat atctcttttg atatttacaa
      121 aggagaaatt tgcggccttg tgggtcaaaa tggtgctgga aagacaacgt taatgcgtat
      181 tttatctggc ctaattggaa aagattcagg gcaaatcaaa cagttacaac cctatcgaat
      241 gggatcaatt attgaatcac cgacacttta tcccaatatg acagctcatg ataatcttta
      301 ctatgcagcg ttgcaattga gattagctga tgcaaaagag cgcatacatg aggttttgga
      361 acttattggg ttagaaaaag tgagcaaaaa gaaaaaggtg aaagattatt ctttggggat
      421 gcgccaacgt ttggctattg gtctttcgat actagatttt ccagaatttt taatcttaga
      481 tgaacccatt aatggtcttg atccagcagg aatcaaagaa atgcgtcaga ttattttgaa
      541 cctaagagat tgctatggta ttacgatttt gatttccagt catattttat cagaattaga
      601 cttagttgtt gatcgttacg tgattatgca taaaggcaaa gttattaaga gtatggacaa
      661 agcagagctt aaagctcaag taaaagtaca aattgccctt catacaagcg atgatcagct
      721 ggtaaaaaat agacttttag aactggggct tagagttgag actgatggtc agatgctact
      781 aataaaacca actttatcag taatggagct tatcaaaatt gtgctagatc tgcctgttga
      841 gatttttgac atttatcatc atcaagtgag ctttgaacat tattacctcg atttgttagg
      901 taaagatgca gcgtcaccat taatttagaa agaggttttt atgatttcct atcttaaagc
      961 agatttattt cggatacgcc aagagcgttt agctctattt tcttgtatgc tacttgttgt
     1021 cattgctgtt ggtgtagcct atagttttcg caagacacct aaccaagtca tcatgataca
     1081 aatcattaat attattactg attttgtgac gcttttcttt ttaacaccag cccgtatctt
     1141 ttttagtgat gactataact accgtacgat taataatgtt gtggtcaaac aacaaaatcg
     1201 tactttaatt ataatctata aactgctagt tagttttggc ttatctcttt tatttattag
     1261 tttaacttat cttcttagtg ctttagcatt tcatttattt actggtcaag catactatgg
     1321 aatagtcata gatcggatga ttaaacaact gcctttttat attgctatta ttgctttgtg
     1381 tcaatttttg tttaatatac ttcgtaaaac ttatcagtca atcacagctt atatacttta
     1441 tgtccttctt tttgataaag tatctgctac tttagcaaac cattttttta agttagatat
     1501 tagcccagtt ttgatgttta aacacctatc cttgtctctt ggtgataaac acctttctag
     1561 tactagcata ttagtggcct ttggtttaac tctttgttat cttttaggca atgtctttct
     1621 tttttccaaa cgagaactaa aataaagggt aatatgtgct ttgtttattt taaaagacaa
     1681 agaagttctt agaaaaaggt cgtcttcatc attactaaaa aaggatgagc aagtagtttt
     1741 gttattattc aagtaagctc atacttaatg agataaaata aagacttgtt tacccggtat
     1801 ctgattgcta agagttggat ttattggaat actggtctca aactgttata gaaatgatta
     1861 tgagtgcaca atctcatagt ttgaaacata gttgtttatt atagacattt aggagatgtc
     1921 ctaatttaaa gcttaaagta ctagaaatgt cccactaata tgttttagtg ggacatttct
     1981 acaggaagct agattatcct tcaatataat cttttagctc ttgaccagta agtccggcgt
     2041 tgagagcaat taataacttt agacgggctt ttggagcatt caattctttt acaaacataa
     2101 cacctgcttc ttgtagcatc gcaccaccac cttcataagc atagacaggt tctgccatac
     2161 cattgaaaca acgggaaaca agaacgacag gaatacctaa agtaattaag tgctcgatct
     2221 ccccaactgc taatggtggg acatttcctg cccctagagc ttcgataact agaccttgaa
     2281 tgctacctgg agttaataga ctcaagatac taccatcgcc catacctgcg tatgctttga
     2341 taatggggat ggttccagaa atgcatctca agtcaaaacg aatacgaggt tcagcagttt
     2401 tgaaaaaaag taggtcattt ttcatgatga taccaagcgg tccgtgtgtg ggtgtttgga
     2461 aagttgaaat attggttgta tgtgttttag taacatattt agcagcatgg atttcatcgt
     2521 tcataacaac aagtacccct ttttctttag ctttatcact acttgcaact ctaagtgcgg
     2581 taaggtaatt atatatgcca tcactaccaa cttcattaga agacctcata gcacctgtta
     2641 ggacaacagg tatattagta ggcaatgcca tggtatctaa aaaataagct gtttcttcta
     2701 aggtatctgt tccatgtgtg atgactatac catcaaagac atcagttctt tcttgaatat
     2761 gatgataaat agataacatg tggtgaggcg tgatgtgagg actcggaaga tttagaaaat
     2821 cactaacggt aagctgaata tcttgggctg cagcatgtat tttcgtcata ggattatctt
     2881 gatttggaac aaccctacca gagttatcag cttgcataga aatggttcca ccagtgtgta
     2941 agactaggat ttttttcatt tgattgtcaa acttcctttt atttatgata taatctattc
     3001 tatcataaac acaggaggca aaagaaggtt ttgacagtaa aagcagtctt ttttgatatt
     3061 gatgggaccc ttctcaatga tcgtaaaaat atccaaaaaa caacgcaaaa agccatccaa
     3121 caactcaaaa aacaaggcat tatggtcggt ttagcaactg gtcgtggacc gggatttgtg
     3181 caaccttttc tagaaaattt tggattagat tttgccgtta cttacaatgg gcaatatatc
     3241 ttaacaagag ataaggtctt atatcagaat caattgccaa agtcgatgat ttacaaagtg
     3301 attcgctatg ccaacgaaaa aaagcgagaa atttctcttg gaacagcttc tggattagca
     3361 ggatcgcgta ttattgatat ggggactagc ccatttggac aagttattag tagttttgtg
     3421 cccaaaagtt gggcaagaac agttgagggt agttttaagc atttgattcg ccgaatcaag
     3481 cctcagagtt tcagaaattt agtaactatt atgcgggagc ctatttatca ggttgttctg
     3541 gtagcgtcac aagctgaaac taagaaaata caagagaagt tccctcatat aaaaattaca
     3601 agaagtagtc cttattcctt ggatctgatc tctgttgatc aatcaaaaat aaaaggaatt
     3661 gaacgtttgg gagagatgtt tggatttgac ttgtctgaag tgatggcttt tggagattca
     3721 gataatgacc ttgaaatgtt atcaggagtt ggtatcggtg ttgctatggg aaatgctgaa
     3781 actgtggtaa aagatggagc ccatttcact accgactcta ataataatga tgggatttcc
     3841 aaagccttag ctcactacgg tctcatccat tttgatgtag agaagagctt taaaagccgt
     3901 gatgaaaatt ttaataaagt caaagatttt catcgtctga tggactcaga tactattgaa
     3961 acaccgcgta gctataccat ttcagaagct ggttataggt caggcttcaa agtagaagaa
     4021 attgttgagt ttctttacgc agcaagcaag ggagaccaac aacaatttac acaggctatt
     4081 ttcgatttgc atggtgctgt tgaccaagca gctaataagg tacaagctaa aaaacatgtt
     4141 gaaacgcccc tgattgggca agttgatgcc ttagcggatt tgctttattt tacttatggt
     4201 tcttttgtac tgatgggagt agatccacaa cctatatttg aagcagtaca tgaagcaaat
     4261 atggctaaaa tttttccaga tggcaaggca cactttgacc ccgttaccca taaaattcaa
     4321 aaacctgact attggcaaga gcgtcacgca cctgaagtag ccataaaaaa agagttagac
     4381 aaacaattac aaaaatcact acaacgattc gataaataga ggtttactct tttaaatatc
     4441 aagaaataaa aagatattga ctagccttag ctcagcacaa aaaaacaagc aatttcgttg
     4501 tagatgctgc ttgttttttg gtgtttgaaa attgtaatag actaaagtgt tttagtgcta
     4561 tctcggacta caagtaagtc aatcttagcg tgtcgcataa tgtactcaga agatgagcca
     4621 ataaggaggc gttcaaaggt attaagacca gtagctccta ccataattaa atcagcgttc
     4681 tcacgatctg gaatatcgtg agctagtaag tttttgggat tgccaaattc aataatttgt
     4741 ttgatgtttg taattcctgc tatctgtgct tgtttttcaa aatcatctaa aacgtcctta
     4801 gcttcttgtt ctaatttttc atagatgtaa gtatcaaaag tagctacgct ttgcaaggca
     4861 cgggtgtcaa taacgtgtac tagtagtaag gtagcgtcgt tacgtagtgc tacgttaacg
     4921 cctttattga aagctaattc agactcataa gagccatcaa tagcaacgag gatacgttta
     4981 tattttagtg acatagaact gtcctccttt aacagtttga caagaatagc ttttattctt
     5041 tttttcatta tactcttttt tgagtcattt tgaaagcgat ccattatttt ggctaaacta
     5101 aagactgtat tatcgtctca taagacctgt gttaaaacga ttagctgtcc taagctttga
     5161 tggataaatt ctttctattt taagtatttt ggtttataat atggaatacg aggtgtatga
     5221 gactatgaaa attattgaaa aatcatcaaa attagaacat gttgcctatg atattcgagg
     5281 gcctgttttg gatgaagcta atcgcatgat tgcgagtggt gaaaaaattc tgcgtttaaa
     5341 tactggcaat cctgctgcct ttggttttga agcaccagat gaagtgattc gtgatttaat
     5401 tgtcaacgcg aggctaagtg agggctattc tgacagtaaa gggatttttt cagcgcgtaa
     5461 ggctatcatg caatattgcc aactcaaggg cttcccagat gttgacattg aagatattta
     5521 tttgggaaat ggcgtgtcag agttgatatc catgtccctt caagctttgc tagataatgg
     5581 cgatgaagtt ttagtaccaa tgccggatta tcctttatgg acggcttgtg tgagtcttgg
     5641 tggaggaaaa gcggtccatt atctttgtga tgaagaagct ggttggtatc ctgatattgc
     5701 tgatatcaaa tcaaaaatca cgagtcgcac caaagctatt gtggtcatca atcctaataa
     5761 cccaacagga gccctttatc ctaaggagat tttagaagac atcgttgctt tggcaagaga
     5821 acaccagctg attatttttg ccgatgaaat ctatgatcgt ttggtgatgg atggtaaaga
     5881 gcatattgct attgcaagtt tggcacctga tgttttttgt gtatctatga atggtctttc
     5941 caaatctcat cgtattgctg gttttcgtgt tggatggatg gtcttatcag gtcctaaaga
     6001 ccatgttaaa ggttacattg aagggttaaa catgcttgcc aatatgcggt tatgctccaa
     6061 tgttttagcc caacaagttg ttcaaacttc cttaggaggt catcaatcag ttgatgcact
     6121 gttactgcca ggagggcgta tttttgagca acgtaatttt atttatgaag ctattaatgc
     6181 tatccctggc ttatcggcag ttaaacctga agcaggtctt tatttatttc cgaaaattga
     6241 tcgtcagatg tatcgtattg atgatgatga agaatttgtc ttacagttat taaagcaaga
     6301 aaaagtgatg ttggtacatg gacgtggttt taactggaaa gatccagatc acttccgtat
     6361 tgtttaccta ccaagtgtag aagaattaga agatgtccaa gaaaagatta cacgtgtctt
     6421 ataccagtat agacgttaat gcaatgctca tctttgatta ataaaaataa cgtttcttaa
     6481 aagaatgtga ccctatgctc taacaagcta gtgcttatct cctttaaatg aagtgataat
     6541 aaggcatcaa tagttggaat tgtagtaaga atagaaaatt ttctgataat tccttgcaaa
     6601 agcgagttag ctttgttata atgaaagcgc aaataattca aaggaaaagg aaaaaatgcc
     6661 taacttatta gaaaaaactc gtaaaatcac atctattttg cagcgttccg tagatagcct
     6721 agaaacagaa ttaccgtata acacaatggc atctcgccta gcagatatca ttgactgcaa
     6781 tgcttgtatt atcaatggcg gcggcacact gcttggttat gccatgaaat ataaaactaa
     6841 cactgatcgt gttgaggaat tttttgaagc taaacaattt ccagatactt atgtaaaggc
     6901 tgctagccga gtttacgata cagaagctaa cctttctgtc gaaaatgaat tgactatatt
     6961 ccctgttgag tctaaagaca cttatccagg aggtctaacg actattgcgc cgatttatgg
     7021 tggagggatg cgccttggat cactcattat ctggcgtaat gacgatgagt ttagtgatga
     7081 tgatttgatt ttggttgaga tctcaagtac tgttgtgggg attcaactat taaatcttca
     7141 gacagaaaac ttagaagaca ccatccgtaa acaaacagcg gtcaacatgg caattaatac
     7201 gctttcttat tcagaaatga aagctgttgc agcaattctt ggagagttag atggtaatga
     7261 aggacgattg acagcttctg ttattgctga tcgtattggt attacccgtt ctgttattgt
     7321 caatgctctg cgtaaactag aaagtgcagg gattattgaa agtcgttctc ttggtatgaa
     7381 agggacatac ctcaaagtta tcaacgaagg tatttttgct aaattaaaag aattttaaat
     7441 agaaaaagac aacatctctt ttcaagagat gttttttgct gttaatggta gatgcaaata
     7501 gatgtcttga tacctgtaat aaaaactgat acaatgccat atataagaga taaggggaga
     7561 ggtttccctg tttaggagat agtgatgaga gcattgattt caattgatta cacaaatgat
     7621 tttgtagcag atgatggtaa attaagtgca ggtaaatctg cccaggctat tgccactaaa
     7681 atagcagagg taactaaaac ggcatttgat caaggagact atattttttt tgctattgat
     7741 tgtcatgatc aaaatgatcc ttggcatcct gagagtaagt tatttgcagc acataatatc
     7801 aaaggaacta ctggacgcca tctttatggt ccactagctg aagtttacag ttatatgaag
     7861 caacatccca gagttttttg gattgataag cgttattatt cagctttttc ggggactgat
     7921 ttagatatta gactacgaga aagaggtatc actcaattag tgttaacagg agttttatct
     7981 gatatctgtg tcttacatac tgctattgac gcttatcatc ttggttatca attagagatt
     8041 gttaaatcgg ctgtcgctag ccttacaaaa gaatcttatg agtggtcttt ggctcacttt
     8101 gagcaggttc ttggtgctaa gcttattaac gattactaaa agatcctacc aaactattga
     8161 ttcagtgact aagagtttgg taaccgtaat cattgctcta tgtggtttta ccgtatgtat
     8221 gggttaggta gatgaggtat gtgacatgct ggtcagaatt agtcctgatg attcttgtgc
     8281 tgtctaaaag gcaactaaac tttggactgt gtcagataga acacatgttt ttttgaagaa
     8341 gacaggattt tagctgtttg agaaatgatt tgagttgatg gtttagagga tcgtctcaca
     8401 gccattagac aaactctagt cttttcagca ttagaatata aataaagctt caaactcttg
     8461 aatgctagag gctgtaccat ttttatctta ggcttatcac atcacatgtt gtcacaatcg
     8521 ttgaggattt ggtaaattag gataaagcac ccctttatta ccttcgtaaa catattaccg
     8581 acttgaaaga acgttacttt ttctgtgatg ttgtaggaaa atgcttggaa gaatacgttg
     8641 acaggggtat ttttgataag gagccgttcc agacctttga tcagaaaggg attggccgtc
     8701 tctttagccc gttcggttaa gcctgagttg aaacttggta tttgtgggga acatggtggc
     8761 gatcctgctt ccattgactt ttaccacagc caaggcctga cctacgtttc ttgttcgcca
     8821 tttagagtgc cgcttactcg cttggcggct gctcaggctg ccatcaaagc ttcaggccac
     8881 agtcttaccc aagacaaata gagtttagtt tgtcacactt cctgactaag gttttctgac
     8941 cttagtcagg aagttttttg ctgtatagct ttctagaatt gcattagtca cctatggtaa
     9001 atgggcgcaa ttgtgatata ataattgaga ctatgtaaaa acgatgtgag gagtttttcc
     9061 gctacctttg gagaatagca gagctgttct ttggaattgg aatacttctg atcatcttgg
     9121 atgggagaaa tcatgaaaat ttctgaagaa gaagctcgcc atgtcgcgaa gctatcaaaa
     9181 ttatcattct cagaaagtga gacaacaacc tttgcaacga ccttatccaa aatcgttgat
     9241 atggttgaat tgctgaacga agttgacacc gaaggtgtcg ccattacaac aaccatggca
     9301 gataagaaaa atgtgatgcg tcaagatatt gctgaggaag gaacagaccg tgccttgctc
     9361 tttaaaaatg ttcctgaaaa agaaaatcac tttatcaagg tacctgctat tttggatgac
     9421 ggaggagatg cctaatgtct tttaatcata aaaccattga agagttgcat gacctccttg
     9481 tagctaagga gatttccgca accgaattga ctcaaaaaac acttgaagac atcaagtctc
     9541 gtgaggaggc tgtcgggtcg tttatcactg tttcagaaga agctgctctt aaacaagctg
     9601 cggcaattga tgccaaaggt attgatgctg ataacctcat gtcgggtatt ccactagctg
     9661 ttaaggataa tatctcaacc aagggcatcc taaccacagc cgcttcaaaa atgttgtata
     9721 actacgagcc gatttttgat gccacatcag tagcaaatgc ctacgctaaa gacatgattg
     9781 tcattggaaa aaccaacatg gacgaatttg ccatgggtgg ttcaacagaa acctcttatt
     9841 tcaagaaaac gaaaaatgct tgggaccaca caaaagtacc tggtggctca tcaggtggtt
     9901 cggcaacagc agtcgcttca ggacaagtcc gtttatctct tggttcagac actggtggtt
     9961 ctattcggca gccagctgca tttaatggtg ttgtcggttt gaaaccaacc tatggcactg
    10021 tttctcgcta tggtctcatt gcttttggaa gttcacttga tcagattgga ccttttgctc
    10081 cgacagttaa agaaaacgcc caattattaa atgtgattgc aagtagcgat gtcaaggatg
    10141 ccacttcagc gcctgtccgc attgcagact acacatctaa gattggtcgt gacattaaag
    10201 gcatgaagat tgcccttcct aaagagtatc ttggcgaagg gattgatcct gagattaagg
    10261 aaacggttct tgcggcagct aaacaatttg aagccttagg agctactgtt gaggaagtta
    10321 gtcttccaca tagcaaatat ggtgtggctg tttattatat tattgcttcg tcagaagcgt
    10381 cttcaaactt acaacgtttt gatggcattc gctatggttt ccgtgctgac gatgctaaaa
    10441 acttggatga aatctatgtt aacactcgta gccaaggctt tggtgatgag gtgaaacgtc
    10501 gtatcatgct tgggaccttt agtttgtcat caggttatta tgacgcttat ttcaaaaagg
    10561 ccggtcaagt gcgtaccttg attattgaag attttgacaa ggtctttgcg gattatgatc
    10621 ttattctagg cccaacaaca ccgacggttg cttttggctt agacacactc aaccacgatc
    10681 ctgttgccat gtatttggcc gacttattga ccattccagt taacttggct ggtctgccag
    10741 gaatttccat tccagcagga ttcgtcgatg gcttgccagt agggcttcaa ttaattggtc
    10801 cgaaatacgc tgaagaaacc atctatcaag cagcagcagc ctttgaagcg gtgacagatt
    10861 atcacaagca acaaccgatt atttttggag gtgacaagta atgaattttg aaaccattat
    10921 tgggcttgaa gtccatgtgg aattaaatac caattccaaa attttctcac cttcgtcagc
    10981 tcactttggt gaggatccaa atgccaacac gaatgtgatt gattggtctt tcccaggggt
    11041 cttaccagtc atgaacaaag gggtgattga tgcgggcata aaagctgcgc ttgccctcaa
    11101 tatggacatc cataaagaga tgcatttcga ccgcaaaaat tatttctacc cagataatcc
    11161 taaagcttat caaatttcac agtttgacga gccgattggc tacaacggat ggattgagat
    11221 taaattggaa gacggttcaa ccaagaaaat tcgtattgaa cgcgcacact tggaagaaga
    11281 tgctggtaaa aacactcacg gcacagatgg ttattcttat gtggacctta accgccaagg
    11341 agttcctttg attgagattg tgtcagaagc cgacatgcgt tctcctgaag aagcctatgc
    11401 ttatttgaca gctctgaaag aaatcatcca gtacacaggc atttctgacg tcaagatgga
    11461 agaaggctct atgcgggtgg atgccaatat ttcccttcgt ccttacgggc aagaacaatt
    11521 tggaacaaag actgaattga aaaacttgaa ctccttctca aatgtccgta aagggcttga
    11581 atttgaggtg gaacgtcaag ccaaactctt gcgttcaggt ggggcgatac gccaagaaac
    11641 gcgccgctat gacgaagcga ataaggggac tattttgatg cgggtcaaag aaggggcagc
    11701 ggactatcgt tatttcccag aaccagacct acccttgtat gagattgatg atgcttggat
    11761 tgacgagatg cgtgctcaat tacctcaatt cccagctcaa cgtcgtgcta aatacgaaga
    11821 ggaacttggt ctctcagctt atgatgctag ccagctaaca gctaccaaag ccttgtcaga
    11881 tttctttgaa actgcagtaa gtcttggtgg cgatgccaag caagtctcta actggttgca
    11941 aggagaagtt gcccaattct taaacgcaga aggcaaaacc attgaagaaa tcgctctgac
    12001 accagaaaat ttggtggaga tgattgctat cattgctgat ggtacaatct cttctaaaat
    12061 ggctaagaag gtttttgtgc atttggctaa aaacggtggc tcagcacgtg cttatgtgga
    12121 aaaagcagga ctcgttcaga tttctgatcc cgctgttttg gtaccaatta ttcaccaagt
    12181 ctttgctgat aatgaagctg cagtggctga tttcaaatca ggcaaacgta atgctgataa
    12241 ggctttcaca ggcttcttga tgaaggcaac caaaggtcaa gctaatccac aagtcgctca
    12301 acaattattg gcacaagaat tgcaaaaatt gcgagattga tagttgctga tagcaataag
    12361 ttaaagtatt ttgtctctga aaaaaaggcg gtcggtcttt cacaggctgc ctttttgtat
    12421 gtcatgttag tgaccgccta taaaaagacc atcatctatg ctaaaataag actgacaggt
    12481 attgctttag aaccttcagg agtttctgac gggtatttaa tgaaccatca cgtttgtcca
    12541 cattattatt agcgattagc tgtgtgataa agtttgttaa gttatttagt gtgtgaagac
    12601 ttctagtcgt tctcggtcta tctatcttaa tagaaggaat tgttttttct attttactca
    12661 ggcacggaaa cacttactaa agaagaaggt aaaggaatca actaaagtta agaacattta
    12721 atggatagca gttcttctaa aaggatttta caagaaagga ggtgttaacg atgatatggt
    12781 ctttaattgt aggtgccttt atcggcatga tagcaggtaa aatgactgaa aaaagccagt
    12841 ccatgggttg ttttactaat attatcacag gtctcatagg gtcagctgtt gggcaaaggc
    12901 tttttgggga ttggggaatt cagttggcag gtatggctat tttcccgtcc attttgggag
    12961 cagcaattgt aattgtactt gtttcagcta tttttggaaa aaggtattaa aaaaaggctg
    13021 catggaagtt tccaagcagc cttttttgca acataaaatg tcttatcttt ttattggttg
    13081 catcctcatt ataagatagt tgtgtgaaaa tttaatatcg ttttcttgac aaatagttag
    13141 attttgttac tgttttgaca tcattttgta acgtcagttt agttgtagtg tgggtctgtt
    13201 gttatatata tttgagcgaa acacacaaat gtaattgttt ggaaatttat gtgatgattt
    13261 gaattgtagc aatagcattg tttttaataa aatagacaat aagtcagtgg tctatttgat
    13321 ctcaaatagc catcaggaag tgttttgcaa gtgttttctt taaatgctat aataattaat
    13381 aagacagttt aggaggttga aatgacaaaa acaaggttgt atattgccag acatggaaaa
    13441 acgatgttta ataccattgg tcgcgctcag ggttggagtg acacacctct tacaaaaaaa
    13501 ggagaagaag gtattcgaga acttggccta ggtttaaaag atgcaactat accatttaag
    13561 gctgcgtttt caagtgattc aggtcgaacc atgcagacaa tagaaattat tttaagagaa
    13621 tcagaaaacg aatttttgcc ttatactaaa gataatcgta ttcgtgagtg gtgttttggg
    13681 agtctagaag ggacttatga ttcagaatta tttctaggtg tccttccaag aacaaaagcc
    13741 tttgaaaatc gtgataacct acgtgatgtt ccctattctg aactggcaga aagcatcgtg
    13801 gaagtagata ccgctaattg ggcagaacca tgggaagttc ttcgtaagcg catttgggag
    13861 gggtttgaag ctattgcctt gtccattcaa aatgctggcg gcggaaatgc tcttgtggtt
    13921 agccatggta tgacaattgg aacgtttctg tggttgattg atccagatcg agacaaacag
    13981 tatattgata atgggagcgt tacagttgtt gaatttgatg atggccaatt tacgataaag
    14041 actattggag atatgagtta ccgctaccgc ggtcgtgaaa taatagaaga acggtcagat
    14101 gaaatataat tcgttaaact atttagtgca attgctaatt gttattgttt ttttaggagg
    14161 gctttacctc tttataaaac cagaagagtc agtaacacca actcagttga ataaaaaaga
    14221 aatccaacaa aaagatatca aaaaaacgga ccgtttacga gctttaccta aggtatctgt
    14281 tgaagattgg gagttggttt tagtaaaccg cgatcacatt acaaaagaaa tgagtcctga
    14341 attagctgac attaatggta tttctgtgga taaacgcatt gagcaagcca ctagtgactt
    14401 tttagcagca gcacaagcta tcgactcgca agaacatctt atctctgggt accgttccgt
    14461 agactaccaa acagagcttt accaatcttc tattaaaaaa gagatggcta acgatccaac
    14521 attgacacaa gaagctgcgg aggctttggt gcaaacctat tcacagccgc caggggctag
    14581 tgaacatcac actggtcttg ctattgacat gagcactgtc gatactttaa atgccagtga
    14641 tccatcagta gctaaagcag ttcaaaaaat tgcacctgat tatgggtttg tcttgcgctt
    14701 tccagaagga aaaaagacta gtacaggggt tgattatgag gattggcatt accgctatgt
    14761 aggcaaggcg tctgctcgtt atatggctca gcacaaccta acgttggaag agtacattgc
    14821 tgctttaaag gagaaacgat gagaaaacga ctaaagtttc cgtatttttt aacgcttcta
    14881 gcttgctttt tattgctgct tgtttgtccc ttactgagta gccaaaggat agctagtgca
    14941 gataaagaag taagggtgaa ctacagccaa aaacaattta ttacaaaaat gggtaaagaa
    15001 gttaaaccat tggcaaaata ttatggcatt agaccatcta ttttgattgc tcaaattctt
    15061 ttggaaaccc atgatggaaa aacattacta gcgtctaagt atcataatct ttttagcaag
    15121 aaagcaactc caggacaagc agccattacc ctaaagtccc ctaaacaaac caaccaaaac
    15181 gtgagatatg ctatttataa agatgacgct agtgcaatta gagattattt acgaatgctt
    15241 cggcagggca aagaagtcga taagcgtttg tatcgtaatc ttgctacaga aaaaggctat
    15301 aaagcaccag ctaaaagttt acaaaagtat ttgcattata ctgataaaac ctatgctagg
    15361 cgactaattc aggttattga aagtaacgat ttaacaaact atgactgaaa ttagcactct
    15421 ttataaaaga gtgctaattt ttttgagttt ttttcttgac atgtctccca taaagagtat
    15481 aatagaatta taaattagca gtctactaaa tagagtgcta aacgaaaggg agtggttggt
    15541 ttgtgattac acaacgtcaa aatgatattt tgaatttaat cgttgagcta tttacacaaa
    15601 ctcatgaacc agtagggtct aaagctttac agagaacgat tgattctagt agcgccacta
    15661 ttcgtaatga tatggcaaaa ctagagaagt tgggattgtt ggaaaaagcg cacacttcta
    15721 gtggacggat gccaagtcca gctggtttta agtattttgt agagcactcc ctcaggctag
    15781 atagtattga tgagcaagat atttatcatg tcataaaagc ttttgatttt gaagcattca
    15841 aattagaaga catgcttcaa aaagctagtc acattttagc ggagatgacg ggctatacat
    15901 ccgttatttt agatgtggag ccagctcgtc aacgtttaac agggtttgat gttgttcagc
    15961 ttagcaacca tgatgctcta gcagtcatga ctttagatga atctaagcca gtgacagtgc
    16021 agtttgctat tccaagaaac tttttgacac gtgacttgat agcatttaaa gctatcgtag
    16081 aggagcgctt gctggataat agtgtcatag atattcatta taagttgagg acagaaattc
    16141 ctcagatcgt tcaaaagtat tttgtgacta cggataatgt tttacaacta tttgattatg
    16201 ttttttcaga gctgtttttg gaaacggtat ttgttgctgg caaggtaaat tctttaacgt
    16261 attcagatct atcaacgtat cagtttttgg ataatgaaca gcaagtagca atttctttga
    16321 ggcaaagtct gaaagaaggt gagatggctt ctgtccaagt ggcagatagt caagaagccg
    16381 cacttgcaga tgtgtcagtt ttaactcaca aatttttgat tccttaccgt gggtttggac
    16441 tcctgagttt gattggtcct attgatatgg attatcgtag gtctgttagt ttggtaaaca
    16501 ttattggaaa ggtattggct gctaaattag gtgattatta tcgataccta aattctaacc
    16561 attatgaagt tcactgataa tggcagtatt caataagtta tttaaaagga ggcactcagt
    16621 gtcagaagaa attaaaaaag acgatttaca agaagaagtg gaagccactg aaactgaaga
    16681 gacagttgag gaagttattg aagaaactcc tgaaaaatca gagttagaac ttgcaaacga
    16741 acgtgctgat gagtttgaaa ataaatactt gcgagctcat gcagaaatgc agaatataca
    16801 gcgtcgctct agtgaagaac gtcaacaact tcaacgctat cgttctcagg atctggcaaa
    16861 agcaatctta ccatcgcttg acaatctaga acgtgccttg gctgttgaag ggttgacaga
    16921 tgatgttaaa aaaggtttag aaatgactcg tgatagcctt attcaagcac taaaggaaga
    16981 aggcgtagaa gaagtagaag tcgactcgtt tgaccacaac tttcatatgg cagttcagac
    17041 cctcccagcc gatgatgaac atccagccga tagcattgca gaagtctttc aaaagggata
    17101 taaattgcac gagcgtctgc taagaccagc gatggtagtt gtttataact aaggtaaatg
    17161 agttttcgtt tttgtccgta atgacagtaa actagatagc aagttagaag ctatttcgct
    17221 tgctgattaa actatagtga ttgcttagaa ttggaagtaa aataattcga gtgcttacta
    17281 agataaattg aaataaaaag taataaagta ttataaaata agaggtatta acatgtctaa
    17341 aattattggt attgacttag gtacaacaaa ctcagcagta gcagttcttg aagggactga
    17401 atcaaaaatc attgctaacc cagaaggcaa tcgtacaact ccttcagtag tatcattcaa
    17461 aaatggtgaa attatcgtgg gtgatgctgc aaaacgtcaa gcagtgacaa acccagaaac
    17521 agtaatctct attaaatcta aaatgggaac ttctgaaaaa gtttctgcaa atggtaaaga
    17581 atatactcct caagaaattt cagcaatgat tcttcaatac cttaaaggtt atgctgaaga
    17641 ctatcttgga gaaaaagtag aaaaagcagt tattactgtt ccagcttact tcaacgatgc
    17701 acaacgtcaa gcaactaaag acgctggtaa aattgcaggt cttgaagtag aacgtatcgt
    17761 taacgaacca acagcagctg cacttgctta tggtatggac aagactgaca aggatgaaaa
    17821 aatcttagtt tttgaccttg gtggtggtac atttgacgta tcaatccttg aattaggtga
    17881 tggtgtcttc gacgttcttg caacagcagg tgataacaaa cttggtggtg acgactttga
    17941 ccaaaaaatt attgatttct tagtggctga atttaagaaa gaaaatggta ttgacttatc
    18001 acaagataag atggcacttc aacgcttgaa agatgctgct gaaaaagcta aaaaagatct
    18061 ttcaggtgtg acacaaacac aaatttcatt accgttcatc actgctggtt ctgctggtcc
    18121 tcttcactta gagatgagct tatctcgtgc taaatttgac gatctcactc gtgaccttgt
    18181 tgaacgtacg aaaactccag ttcgtcaagc tctttcagat gcaggattgt cattgtcaga
    18241 aattgatgaa gttatccttg ttggtggatc aactcgtatc ccagcagttg tcgaagctgt
    18301 aaaagctgaa actggtaaag aaccaaataa atctgtaaac cctgatgaag tggttgctat
    18361 gggtgctgct atccaaggtg gggttatcac tggggatgtg aaagacgttg tccttcttga
    18421 cgtaacacca ttgtcacttg gtattgaaac aatgggtggt gtcttcacta aattgatcga
    18481 ccgcaataca actatcccaa catctaaatc acaagtcttc tcaacagcag cagacaacca
    18541 accagccgtt gatatccatg ttcttcaagg tgaacgccca atggcagcag ataacaagac
    18601 tcttggtcgc ttccaattga ctgatatccc agctgcacct cgtggaatcc cacaaattga
    18661 agtaacattt gatatcgata aaaacggtat tgtttctgta aaagctaaag accttggtac
    18721 gcaaaaggaa caacacatcg ttatcaaatc aaacgacgga ctttctgaag aagaaattga
    18781 tcgcatgatg aaagacgctg aagctaatgc cgaagccgat gcgaaacgta aagaagaagt
    18841 tgaccttaaa aacgaagttg accaagctat ctttgctact gaaaaaacaa tcaaagaaac
    18901 tgaaggtaaa ggctttgata cagaacgcga tgcagcgcaa tcagctcttg acgagttaaa
    18961 agctgcgcaa gaatctggca accttgacga catgaaagct aaacttgaag cattaaatga
    19021 aaaagcgcaa gctttggctg ttaaaatgta cgagcaagct gcagcagctc aacaagcagc
    19081 acaaggtgca gaaggtgcac aagctaatga ttcagcaaat aatgatgatg ttgtagatgg
    19141 cgaatttaca gaaaagtaat gatttagtta tctagtaaca ttaatatccg aattcagagg
    19201 ttgcaccaaa cctctgtttt tggctaaata aaatgtaaaa atgctgacgt caaaatattt
    19261 taagaaagga atacaagttc gattattcga acacaggcta aagcgtgtaa agactctttt
    19321 gcggatttga acacgcctac gaccctgcga aaaaagagaa atacctccta gatacgagag
    19381 tatctttgtc ggatttccta tttttcattg agtcgtttta cggcttggta tcttacatta
    19441 tgaacaatac agaatattac gatcgtctgg gggtttctaa ggacgcttct caggacgata
    19501 tcaaaaaagc ttatcgaaaa atgtctaaaa aatatcatcc agatatcaat aaagaagctg
    19561 gagcggagca aaagtataag gatgttcaag aagcttacga aaccttaagt gattcacaaa
    19621 agcgtgctgc ttatgatcaa tacggcgctg caggtgctca aggtggcttt ggtggtggag
    19681 caggcggctt tggtggtttt gacggaggtg gctttggtgg ttttgaagat atcttctcaa
    19741 gcttctttgg tggcggtgga agccgaaacc caaatgcccc tcgtcaaggt gacgatttgc
    19801 aatatcgtgt taatttatct tttgaagagg ctgtatttgg tgttgaaaaa gaagttagct
    19861 ataatcgcga agcaacctgc ggcacttgtt taggctcagg tgcaaaacct ggtaccgctc
    19921 cagtaacttg tcgtaagtgc catggttcag gtgtaatgac aattgacacc caaacaccac
    19981 ttggtatgat gcgtcgacaa gtcacctgcg atatttgtca tggtagtggt aaggaaatta
    20041 aagaaccctg tcaaacctgt cacggtactg gtcatgaaaa gcaagctcat aaagtgtctg
    20101 ttaagattcc agctggtgta gagactggtc agcaaatccg tttacaaggt caaggagaag
    20161 ctggctttaa tggcggacct tatggtgatt tatttgttat tttgaatgtc ttaccaagta
    20221 agcaatttga acgcaatggt tccactattt actacaactt agatatttct tttactcaag
    20281 cagccttagg agatactgtt gaaattccaa cggttcatgg cgatgttgag atggctatcc
    20341 ctgctgggac acaaacaggt aaaaccttcc gcctcaaagg caaaggagca ccaaaactcc
    20401 gtggtggagg tcaaggggat caacatgtta ccgttaatat tgtgacccca accaaactca
    20461 atgacgctca aagggaagcc ttgcaagcat ttgcagaagc gagtggtgaa aaaatgttac
    20521 atccaaagaa aaaaggtttt tttgataaag tgaaagatgc cttagaggat atttaaagat
    20581 gtcaaacgta taatctcagg ataattttcc cgaagttata cgttttttta cgtcaaaaca
    20641 gttagagaaa acgttttctt ttatagatat cgtttttttc tcttgtcaaa atggtttatt
    20701 tagtatatca taattaggta attgatttga ttatcaaatg attttaaaga gaaataattt
    20761 cttagtcaaa taaattatca gaaaagagga ttgttatgca gtttaaacac atcatctttg
    20821 atgttgtaga tgatcttgcg acattgactt taaaccgtcc agaggtttca aacggtttta
    20881 atattccaat ttgtcaagag attctggtag cattagcaga agttaaacgc gatacatctg
    20941 tgcgtttttt attaattaaa gccgttggaa aagtgttttc agttggtggt gacctagttg
    21001 aaatgcaaga agctgttgca aaagataatg tgcagtcgct agtcaagatt gctgaactgg
    21061 tacaagaaat ttcttttgca atcaagcatt tgccaaaacc agtcatcctt tgcgccgatg
    21121 gagctgtagc tggagcggct tttaatatag ctttagctgt tgacttttgt atcgctagta
    21181 ctcaaacaaa atttatccaa gcttttgtaa atgttggact agcaccggat gccggtggtt
    21241 tatttctatt gactcgtgca gtaggactta atcgtgcaac tcaccttgtg atgacaggtg
    21301 aaggaattac tgctgataaa ggtctcgatt atgggtttgt ctaccgtacg gcagaatctg
    21361 ataaactaga caaagtttgt cttcaacttt taaagcgatt gagacgtggc tcttcaaatt
    21421 cttatgctgg aatgaaatca ttggtctggc aaagcttttt cacaggatgg gaagattatg
    21481 ctaaggcaga gcttgctatt caagaggagc tagctttcaa ggaagatttt aaagaaggtg
    21541 tcatagcttt tggagaaagg cgccgaccaa attttcaagg taagtagact catgcttgca
    21601 aagtgctttt aactctgata taatttgact gtcaaagttt tattgttagg aggtatttgc
    21661 ttggaatatg acaaaatcaa tcactacttg gttgatatct tcaaccgtat tttggtaatt
    21721 gaagagatga gtttaaaaac cagtcaattt aatgatgtct ctttaaaaga gatgcacact
    21781 attgaaatta tcggcaaata tgatcaggtg actccaagtg atatcgccag agaattaatg
    21841 gtaacgttag ggacagtaac cactagctta aataaattag aagcaaaagg ttatatcgca
    21901 agaacgcgat cacgctcaga taggcgagtt gtttacctgt cattaacaaa aaggggtcga
    21961 cttttggacc gcctccatgc aaagttccat aaaaatatgg ttggacatgt cattgctgat
    22021 atgagtgatg aagagatgca ggcattggtg cgtggactag ggaatctaca tcaatttttg
    22081 gaggatttgg tttaaatgat tttttctaaa atcagtcagg tagcccacta tgttccacag
    22141 cagttagtga ctaataatga tttagctaac ataatggaca ctagtcatga gtggatcttt
    22201 tctcgaacag gaatagcaga acgccatatt tctagagatg aaatgactag tgacctagct
    22261 attcaggttg ctgatcagct tttaactcag tctgggttaa aagctgatgc tattgatttt
    22321 attattgttg caactatcag ccctgatgcc actatgccat caacagctgc gaaagttcaa
    22381 gcagctattg cggctacaag tgcttttgct tttgatatga ctgctgcttg tagtggcttt
    22441 gtctttgcct tggctatggc agataagctt attgcatcag gtgcctacca aaacggaatg
    22501 gtaataggtg cagagacttt atctaagtta gtaaactggc aggatcgagc gacagccgtt
    22561 ctttttggag acggagctgg tggcgtgcta ctggaagcca gtaaagataa gcatgtttta
    22621 gcggaaacat tacacacaga tggtgcgaga tgtcagagtt taatttcagg agaaactagt
    22681 ctttcatctc cttactcaat tggcaaaaaa gccatagcga ctattcagat ggatggacgt
    22741 gccatatttg attttgcgat tagggatgtg tcaaaaagca tcctcacact aatggcgcaa
    22801 tcagatatta caaaagatga tatagactat tgtttattgc atcaagctaa tcgtcgtata
    22861 cttgataaaa tagcacgcaa gattgatgtt cctcgggaaa aattccttga aaacatgatg
    22921 cgttatggta atactagtgc tgctagtatc ccaatcctct tgtcagaggc tgttcaaaag
    22981 ggacagatta ggttagatgg tacccaaaaa atcttacttt ccggttttgg tggaggtttg
    23041 acatggggaa gtctaattgt tagaatctag ttattcatgt gcctagcaca tttataaaaa
    23101 caaatttata ttttttaagg agaaataaac atggcagtat ttgaaaaagt acaagaaatt
    23161 attgttgaag aacttggtaa ggagacagaa gaagtaacac tagaaactac atttgatgat
    23221 ttagatgcag attcacttga tgttttccaa gttatttcag aaattgaaga tgcttttgat
    23281 attcaaattg aaacagaaga aggattaaat actgttggtg accttgttgc ttacgttgag
    23341 gaaaagtcaa aataaggata aaagtgacaa gtaacatcag aagtctatga aaagcttact
    23401 gctgttatgt tcatgttcat cactaaaaaa aacaataagt attaatcaaa ccattagggt
    23461 gggattagac tctttttagg atctagctcg ctctttcttc ttactataat agtttgatta
    23521 tcaaattatt ctccttattt tttatagaaa gttattatga aaacacgtat tacagaatta
    23581 cttaatattg attaccccat ttttcaagga ggaatggctt gggttgctga tggtgattta
    23641 gcaggtgcag tttctaatgc tggtggttta ggcattatag gtggtggcaa tgctcccaaa
    23701 gaagtcgtta aagctaatat tgatcgtgtc aaagctatta ctgatagacc ttttggggtt
    23761 aatatcatgc ttttatctcc ttttgctgat gatatcgttg atttggtcat tgaagaaggt
    23821 gttaaagtag taacaacagg cgcaggaaat ccaggaaagt atatggaaag actgcaccag
    23881 gcgggtataa tcgttgttcc tgttgtccca agcgttgcgc tagccaaacg tatggaaaag
    23941 ctaggggtag atgctgttat tgctgagggt atggaagctg gaggacatat tggcaagtta
    24001 acgactatgt ctttagtaag acaagttgtt gaagcggttt cgattcctgt cattgcggca
    24061 ggtggtatag ctgatggtca tggtgcagca gcagcattta tgttaggagc agaggctgtt
    24121 caaattggaa ctcgctttgt tgttgctaaa gaatccaatg cccaccaaaa ttttaaagat
    24181 aaaatcttag cagcaaaaga tattgatacg gtgatttctg cgcaggttgt gggccaccct
    24241 gtccgttcta ttaaaaataa attgacctca gcttacgcta aagcagaaaa agcattttta
    24301 attggtcaaa aaacagctac tgatattgaa gaaatgggag caggatcgct tcgacatgct
    24361 gttattgaag gcgatgtagt caatggatct gttatggctg gccaaattgc agggcttgtg
    24421 agaaaagaag aaagctgtga aacgatttta aaagatattt attatggtgc agctcgtgtt
    24481 attcaaaatg aagctaagcg ctggcaatct gtttcaatag aaaagtagat aaacacatga
    24541 aggataatga taatgacaaa gacagccttt ttatttgccg gtcaaggtgc ccaaaaatta
    24601 gggatggcaa gggattttta tgataacttt gctattgtaa gaaaaacctt tgatcaagct
    24661 agtcaagtat tgggatacga tttgcgccgt ttgattgata gtgacgagtt aaaacttaat
    24721 caaactagct atactcagcc agctattttg acatcatcaa ttgctattta ccgtgttttg
    24781 ggcttacatc acgttaaacc ggatatggta gctggtcttt ccttaggaga gtactcagct
    24841 ttggtagcat caggggcact ctcttttgaa gataccctat ccttagtagc taagagaggg
    24901 cgcttgatgg aggaagcagc accacaagga tctggaaaga tggttgccgt tatgaataca
    24961 gacgtgcaag tcatcgaaga agtctgtcaa atagctgcta aacatggagt ggttgctcca
    25021 gcaaactata atactcctag tcaaattgta attggtggtc agacagatgc tgtgaacgtg
    25081 gcagttgaac ttttaaagga aaggggagtt aagcgtttaa tccctttaaa cgtgtcaggt
    25141 cctttccaca ctgctttgtt agaaccagct agccgcttgt tggctaaaga gttggaaaga
    25201 tacaacttca gtgacttcaa gattcctttg gttggtaata ccgaagctaa tattatggaa
    25261 aaagaccgta tcccagaact attagcccgt caagtcatgg agcctgttcg tttttatgac
    25321 agtgttgcga ctttagtaga aagtggcata acacaattca ttgaggtagg accaggtaag
    25381 gttttgacag gttttgtgaa gaaaattgat aaaaatttac tatgtactag tgttgaaaac
    25441 atggtaagct tacgtttatt tttagataga gaggacattc atggaaatta aaggaaaaaa
    25501 tatatttatc acaggctcaa cgagaggtat cggtttagca atggctcatc aattcgccag
    25561 tttaggagct aatattgtct taaatggtcg ctctgctatc tctgaggagc ttgttgctag
    25621 ttttactgac tacggcgtta cagttgttac catctctggg gatgtttcag aagcatcaga
    25681 agctaaacgt atggtcaatg aagctatcga aagtttaggt tcgattgatg ttttagttaa
    25741 caatgctggc attactaatg ataaattgat gcttaaaatg acggaagagg attttgagcg
    25801 cgtcttgaaa atcaatttga ccggtgcttt taacatgact caatcagtgt taaaaccaat
    25861 gatcaaggcc cgccaaggag caattattaa tgtctctagt gtggttggtt taacaggcaa
    25921 tattgggcaa gcaaactatg ccgcttctaa ggcaggaatg attggtttta ccaagtctgt
    25981 tgcccgtgaa gttgctgctc gtaacatttg cgtgaatgct attgctccag gatttatcga
    26041 gtccgacatg acaggtgtcc ttcctgaaaa aatgcaagag caaatcttaa gtcaaatccc
    26101 aatgaaacgt attggaaaag ctcaagaagt tgctcactta gcaagcttct tggtggaaca
    26161 agattatatt acgggacaag ttatcgctat tgatggcggt atgacaatgc aataaggaga
    26221 cgtagtgaaa tgacatttaa aagagtagtg gtaacaggtt atggtctaac atctccaatc
    26281 gggcatgatc ctgaaacgtt ttggaacaat ctgaaagctg gccaaatcgg tattggccct
    26341 attactaaat ttgacacgac tgattatgcg gtcaagaatg ctgctgaaat tcaggatttt
    26401 ccatttgaca aatactttgt gaaaaaagat ttgaaccgtt tcgatagata ttctctttat
    26461 gctctttacg cagcgaaaga ggctattaat catgctgatt taaatattga gatgattgat
    26521 tccgatcgat ttggcgttat tgtcgcttca ggtattggtg gaattgcgga gattgaagag
    26581 caggtgattc gcttacatga aaaaggacca aaacgtgtga agccaatgac gttgccaaaa
    26641 gcgctaccaa atatggctgc aggaaatgtc gccatgtctt taaaagctca aggagtatgt
    26701 aaatcaatta atactgcctg cgcttcttca aatgatgcga ttggggatgc ctttcgtgcc
    26761 attaaatttg ggactcaaga tgtgatgata gttggtgggt cagaggcggc cataaccaag
    26821 tttgccattg ctggcttcca aagtttaaca gctctctcaa caactgaaga tccaagcaga
    26881 agctctattc catttgataa agaccgaaat ggttttatca tgggagaagg atcaggaatg
    26941 cttgttttag aaagcctaga acatgcgcaa gaacgcgggg cgacaatctt agcagaaatt
    27001 gtgggttatg gaaatacctg cgatgcttac catatgacat ctccaaatcc tgagggatta
    27061 ggagctcgta aagccatcca cttagcctta caagaagctg gtattgaagc cagtgctatt
    27121 aattatgtca atgcgcacgg aacttcaacc ccagctaatg aaaaaggaga gagtcaagca
    27181 attgtagccg ttcttggtaa ggatgttccg gtgtcttcaa caaaatcgtt tacgggtcac
    27241 cttcttggag cagcaggcgc tattgaagct attgccacta tcgaggctat gcgtcataac
    27301 tatgttccga tgacggctgg gacacaagct ttatcagagg atatcgaagc aaatgtcatc
    27361 tttggagaag gaaaagaaac agctatcaac tatgccattt caaatacttt tggatttggt
    27421 ggtcataatg ctgtattagc tttcaaatgt tgggaggagt aggttgaata ttcaagaaat
    27481 caaagatttg atggctcagt ttgatacctc aagcctacgt gaatttttat tcaaaacaaa
    27541 tgaaggtgag ctaatcttta gtaaaaacga acaacacctc aatgcatcga catcaaatca
    27601 agaacatgct gtgcctgtac cacaggtaca acttgttccg aatccaactg cttcggaagc
    27661 gtctagtcca gcatcagtta aggatgttcc tgtagaggag caaccacaag cagaatcttt
    27721 tgtagcagaa ggtgatattg ttgaaagtcc tttagtcggt gtagcctatc ttgcagctag
    27781 ccctgacaag ccaccatttg tggcagtcgg agatactgta aaaaaaggac aaacccttgt
    27841 gattatcgaa gccatgaagg tgatgaacga agtgccagcg ccatgtgatg gtgtgattac
    27901 agaaattttg gtatcaaatg aagatgtcat tgaatttgga caaggattgg tgcggatcaa
    27961 atgatggata ttagagaaat tcaagcggct ttgcctcatc gctacccaat gttattggtt
    28021 gatcgtgtat tagaagtgtc agacgaccat atcgttgcca ttaaaaatgt gactattaat
    28081 gaacctttct ttaacgggca ttttcctcac tatcctgtga tgccaggtgt tctgattatg
    28141 gaagctttgg ctcaaacagc tggtgtctta gaattgtcaa aagaagaaaa taaaggcaag
    28201 ttggtctttt acgctggaat ggataaagtg aagttcaaaa aacaagtcgt ccctggtgat
    28261 caacttgtga tgacagcaac ctttatcaag cgtcgcggta ccattgctgt cgttgaagcc
    28321 agggcagaag ttgatggcaa gctagcagca agtggaacat taacctttgc ctgtgggcaa
    28381 tgagaatgat tgttctgcgg aggaagaaac ccttatgttt aaaaaaatct taattgctaa
    28441 tcgtggtgaa attgcagtgc gtatcattcg tgctgcacga gaattaggga tttccacagt
    28501 tgcagtttat tcggaagcgg ataaggaagc tctgcacacg atattggcgg acgaggctat
    28561 ctgtattggt cctgcccgtt ccaaggaatc ctatcttaat atgaattccg tcttgtcagc
    28621 agctattgtg acaggagcgc aagcgattca cccagggttt ggctttttaa gtgaaaactc
    28681 aaagtttgcg accatgtgtg aagagatgaa tattaaattt atcggtccat ccgcatcggt
    28741 tatggataaa atgggtgata aaatcaatgc tcgttctgaa atgattaagg caggagtgcc
    28801 cgttattcca gggtcagatg gtgaagttta taacgctcaa gaagccttag ctattgccaa
    28861 taagattggt tatcctgtca tgctaaaagc atcggcaggt ggtggaggta aagggattcg
    28921 taaagtggag acagaagcag atttggaggc ggctttcaat gctgccagtc aagaagcttt
    28981 gggagctttc ggaaatggcg ccatgtattt ggaaaaagta atttatccag ctagacatat
    29041 tgaggtgcaa attttaggag acgcttacgg taacatcatt cacttgggag aacgggattg
    29101 ctcgttacag cgtcataatc aaaaagtctt ggaagaaagt ccatccattg ctattggcaa
    29161 taccctcaga cacgaaatgg ggcaagcagc ggttagagca gctgaagctg tagcctatga
    29221 aaatgcggga accattgagt ttttgttgga cgaagacagc gagaaattct atttcatgga
    29281 aatgaatacc cgtatccaag ttgagcatcc tgtcaccgaa tttgtgacag gagtggatat
    29341 tgtcaaagag caaatcaaaa ttgcagcagg tcagcctttg gcgattaatc aagaagacat
    29401 cactatcacg ggacatgcta ttgaatgtcg tatcaatgct gaaaatactg cttttaactt
    29461 tgcaccgagt ccaggaaaga ttacagactt gtatatgcca agtggtggtg taggactacg
    29521 agttgattca gcagtttaca atggctatgc cattcctcct tattatgaca gcatgattgc
    29581 taaaatcatc gttcatggaa gcaatcgatt tgacgctttg atgaaaatgc aacgtgcctt
    29641 agttgaattg gaaattgaag gcattatcac caatacagac ttccagctcg atttgatttc
    29701 agataagcga gtgattgcag gagattatga tacctctttc ttgatggaaa cgttcctgcc
    29761 acattacaat aaagattagg agaaaatatg gctttatttc gtaaaaaaga taaatacatc
    29821 cgtattactc ccaataattc cctcaaagga tctgtcagcc ataatgtccc agaagttcca
    29881 gatgaactct ttgcgaaatg cccagcttgt aagcacatga tttataagaa agatttggga
    29941 ttggcaaaga tttgcccaac ctgttcttac aattttagga tttctgccca agagcggctg
    30001 accttaacag ttgatgaagg ctctttccag gaattattta caagtattga aaccaaggat
    30061 ccgttacgtt ttccaggtta tcaggaaaaa ttacaaaaag ccaaggaaac aactggtctg
    30121 catgaagctg ttttgacagg gaaagctatg gttaaaggac aacaaattgc acttgctatt
    30181 atggattctc actttattat ggctagtatg ggaactgttg ttggggaaaa aattacccga
    30241 ttgtttgaat tggctatcga agaaaacctg ccggtggtga tttttacggc ttcaggaggt
    30301 gcccgtatgc aagagggtat catgagcctt atgcaaatgg ccaaggtctc tgcagctgta
    30361 aaaagacatt ctaatgcagg cctcttttac ctcactattt tgacagatcc aactactggt
    30421 ggggtaacag ctagttttgc catggaaggg gatattattt tagcagaacc tcaatccttg
    30481 gttggatttg ctggacgccg tgttattgaa accacagtac gtgagaattt gccggatgat
    30541 tttcaaaaag cagaattttt acaagaccat ggttttgtgg atgctattgt gaaacgaaca
    30601 gagttgcgag acaagattgc ccacttagta gcatttcatg gaggtggcca atgacagatg
    30661 tatcaagagt tttaaaagaa gcgcgtgatc aagggcgttt aacaactttg gattacgcca
    30721 accttatttt cgatgacttt atggaactgc atggcgatcg ccatttttca gatgatggtg
    30781 ctattgtagg tggcttagct tatttggcgg gacaacctgt tacggtcatt ggtattcaaa
    30841 aaggtaagaa tttacaggat aatttggcaa ggaattttgg ccagcccaat ccagaaggtt
    30901 atcggaaagc cctacgttta atgaaacagg cagaaaaatt tggacgaccc gttgtcacct
    30961 ttatcaatac tgcaggagct tatccaggag ttggtgcgga ggaacgagga cagggtgagg
    31021 ccattgctaa aaatttgatg gaaatgagtg atctcaaggt tcccattatc gccatcatta
    31081 ttggtgaagg gggctctggt ggtgcattag ccttagcggt tgccgatcag gtctggatgc
    31141 ttgaaaatac catgtatgcg gtccttagcc cagaaggctt tgcttctatt ttatggaaag
    31201 atggttcaag agcgacagag gctgctgaat tgatgaaaat taccgcaggc gaattgtatc
    31261 aaatgggcat agtagatcgt attatcccag aacatggtta tttttcaagt gaaatcgttg
    31321 acatcatcaa agctaacctc atcgaacaaa taaccagttt gcaagctaag ccattagacc
    31381 aattattaga tgagcgctac aaacgctttc gtaaatatta acaacatcct tttggagtct
    31441 ccctacgtgt ttatcaagct aagggaggcc tttccaaaag ggtttttaac tagtcttgta
    31501 aataaggaaa tgggtatact ttgataaact agtgtgaaga aaagtgttgt taaaggggca
    31561 atgtagtgag tttcaagtga tgtggtggct ctttaaaata gtaaacccca gaaatcactt
    31621 taatgatctc tggggtgagt ttattattta ggtgaaatga cggtttcgcc acccatgtaa
    31681 gggcggagta cttcagggat ggtaacagaa ccatcttcat tttggtagtt ttctaaaatg
    31741 gctgctacgg tacgaccgac agcaagtcct gacccattaa gggtgtgaag aagtttgacc
    31801 ttaccgtcag cctcatcacg gtaacggatt tgagcacgac gtgcttggaa atcttctgta
    31861 tttgaacatg atgaaatttc acgataggta ttttgtgcag gaatccagac ttcaaggtca
    31921 taggttttag cagctgagaa gcccatgtct ccagtacaaa gggaaatgac gcgatatggc
    31981 aaaccaagtt tttgaagaat attttcagca ttagcagtca ttttttctag ttcttggtaa
    32041 gattcttctg gtttagcaaa tttaaccatt tcaactttgt ggaattggtg taggcggata
    32101 aggccacgtg tgtcacgacc cgcagaaccc gcttcagaac gaaaagatgg gctcattgca
    32161 gtaaagtaaa ttggcaattc tttgccgtct aggatttccc cacggtaata attggtcaaa
    32221 ggcacttcag cagttggaat caggacaaag ttggtatctg ctaattcaaa ggtgtcctct
    32281 ttgaactttg gatattgtcc tgtaccaaac atggaatcgt ggttaaccat gtaaggtgtg
    32341 atgatttctt gataaccttc tttgatatgt tcatccagca tgaagttata aagagcacgc
    32401 tccaaacgag caccaagatt tttatagaat aagaaacgag caccagttac ctttgcccca
    32461 cgttcccagt ctaaaatatc aagatcttcg cctagatccc aatgagcctt aacttcgaag
    32521 tcaaagtcac gaggcgttcc ccaacggcga atttcgacat tgtcttcttc gtcagctcca
    32581 acagggacag aatcgtgagg agtattaggt aaaacagtga tgatgtcagt aacttgctgg
    32641 tcgatagcta ctagttgatt gtcaatagtt ttgatatctg cagagacttt ttgcatatca
    32701 gcaatttgtt gagtggcatc ttctttttga cgttttgctt gggcgatggc tgcagaagca
    32761 atattacgct ctgcttttaa ttcttctgat tgcactaata gagcacgacg tttttcatca
    32821 agttctttaa gatgggtcag ggtgtcttca gaaacaccgc ggttttttaa tttggcagcg
    32881 acagtgtcaa aatcggtacg gatacgttta agatctagca tacagaagct cctttaagat
    32941 agttattagt agctgtcagt gaaacaaggc taagtaagac agttggatct tgtgattctc
    33001 tgacgataga aaaagcacag cttatgaaga tgctggagcg ctttggcgcg gttccatcca
    33061 gcttcacaat ctgtgcactt aatctatatt ttattgatga cacggtagaa tttcatatca
    33121 ttttccctat ctgttcacag catccacaga ctctctgaat gaaaaaaagg tattacttat
    33181 ccgttaggac tattataaca aaaaacaaga aaaagtaaac tcaaatgagg gaatcttttc
    33241 cactaaatag caatttagag ctactattct ttgctttctt gaaatgataa atcggcactg
    33301 cgcattattt ttttaatgtc gaaaaaattt gttaataaag gtttgcatca aggttggtaa
    33361 tgtaatcact ttctcattac caatatgttg acgagtgatt tttaagattt ttccagagtc
    33421 tccagaagca aataaaaact tgccttggtc cgtaaaaatt tcaaagtggc ggctaacttt
    33481 ttttcttgaa acattagccc cgatgtgatt gatagctgtc caaggaattt gaatataatc
    33541 attcacattt ttatcgttgt aaaattcaag ggccttgtca ccgagtaaaa tatgaccaac
    33601 tttgcctccc attccaaggt aggagacagc ttttgtcttg tattcgacac tagtgtttaa
    33661 agattgagcc attttagttc ctttcattgc gtagttgtag ttattatacc atattttaag
    33721 tgggattttc ctgacataaa gcataaaaaa gaagcctgag ttcatctcag acttccattg
    33781 gttgattaca taatacctgc aaggtgagca aggataccaa atgcaaacaa gccgatgatg
    33841 attgcgattg gagaaacttt tttcttcaat aaccacatgc aaaggaatgt aaggagtaat
    33901 ccagctaaac ctgggataag agagtccaat tgtccttgaa gggtttgagc ttggacttta
    33961 tcaaggctca taccaccaat agcgttggca aggatagttt tcaactcagc acctttaaca
    34021 gcgccatctg ggaagaccac ataggcacca tctgacaatt gttttccagg aaggtcgata
    34081 gtaaagttga tagataccca acgttgaaca agcactgcaa ggataaacat tccaaggatt
    34141 gaagcacctt tagtaatgtc ttggaggata ccgcctgaca tgtctttagt aatttcagaa
    34201 ccagctttgt aaccaaattc ttgagtatac cataagaagg ccatacggat aaggttccat
    34261 ccaaagaaga acagaagtgg accaacgatg ttacctgttg aagccaaaga agcaccaagt
    34321 gccccaagga taggacgaac cgtaaaccag aatactgggt caccgatacc agcaagaggt
    34381 cccatcatac cgattttaac cccttggata gccttgtcat caattggcgt accatttgcg
    34441 cgttcttctt caagggcaag tgttacacca atgattggag ctgcaacgta tgggtgagtg
    34501 ttaaagaatt ccatgtggcg ctcaagagca gctgcacggt cttcaggaga cgtatacaat
    34561 tttttaagag cagggataag tgcataagcc cagcccatgt tttgcatacg ttcgtagttc
    34621 caagaacctt gtaagaattg tgaacgccac caaacacgtt gacggtctga tttagttaat
    34681 ttaatttgtt cagtcatttg ttcttacccc tttctagtag tcttctaaga tgtcgccgat
    34741 tggatcagct gaacctgctg cattaccacc gttaccacct tttttagaaa gattaaggta
    34801 gatgaaggca attgctacac cgataatacc catagcgata agggttaatt ggctgatagc
    34861 tgcaagagca aaacctaggg cgaagaatgg ccatacttca cgagtagcca tcatgttgat
    34921 aaccatagca taacctacag caacaaccat cgcaccaccg atttgcatac cttcgttcaa
    34981 ccagtttggc atagcattca aaacagattg tacggctgaa gtaggaacag caacaagaag
    35041 agctgctggg acagcgatac gcaatccttg aagaagaagg gcaataaagt ggaagcgttc
    35101 aatacctgcg aaattacctt cagcggcagc tttgtcacca gcgtgtacaa gggcagttga
    35161 caaagtacga acgatcattg taaggaaaag accagcaaca gcaagtggga tagctgttga
    35221 gtaagcaaag gtaattcctt tttgagtaaa gtcgccactt ttgaccatga tgatagcagc
    35281 tgcaacagag gcaagggcag catcaggggc aacggcagca ccgatgtttg cccaaccaag
    35341 agcaagcatt tgaagtgtac caccaaggat gacaccagct tcaaggtgtc cagttacaag
    35401 tccaatcaaa gtacaggcaa caagtggttg gtgcatttga aattggtcga ggataccttc
    35461 aagaccagcg aagaaggcaa tgataacgac caaaattgca gaaataatcg aaatatctga
    35521 catgttgtaa tcctttcaaa gtatagtaaa cgaggccttt ttgctaataa gttagctagt
    35581 catcgtttta aaaccttata gcgtttgaaa cttatttaat gttagctttt tggataagct
    35641 caaataagtt tttcttagaa tcgttaggaa ctttacggac gtcgaatgta acacctaggt
    35701 cgcgtaattt ttcaaaagta gcaacgtctt ctttgtccat tgataaaacg ttgttaacca
    35761 ttgttttacc agttgagtga gccattgaac caacgttcaa ttcgttgatt tcaacaccac
    35821 cttcaaccgc tcgaagggca tcttgagggg tttggaaaag aataagtgcg tgtgtgttac
    35881 caaaacgagg atctttagaa gcttcaatca atttgctaat tggaacaacg ttagctttga
    35941 caccaccagg tgcagcctgt ttgatcaatt gtttgcgaag gtcatcttga gcaacctcat
    36001 cagaagcaac aatgatacga tcagccttag aagctggagt ccatgctgtt gcaacttgac
    36061 cgtgtaaaag acgagtgtca acacgagcaa gattgatctt taatttacca tctccgatga
    36121 cagttccagc aggaatagct ccttgaagtg cgttaacaac tttttcagtt gcagcagttt
    36181 cttcaactgg gttaaggtct tcaggaaggg ctttgatacc gtccttagat tccttaatga
    36241 tgtttgcagc aacttgttca acacctgcac cagcatccat aagacgttca gtgtaagctt
    36301 gaataagcat aggcaagttg agaccagtga tgatcgccat tttgcggtca ggattttcac
    36361 ctgccacacg actagcttgg ttaaatggag aaccactcca aaggtcagct agcacaagga
    36421 tttcatcatc agcatcaaat tgttggatag cattgttgaa gtgtccatac aaatcatctg
    36481 gtccttcgtt tggcatgaaa gtaacaactt gaactttctc ttgttcacca aaaatcatag
    36541 aaccagattg atgaatacct tcagcaaatt taccatggct ggcaataata ataccgatac
    36601 ccattcttgt tcttcctcct ttaaaatatt cttcgttgaa atgaagaaga ataatctcct
    36661 tccaaaacta aattttggca attctttttc acttaaacga aattcaagaa cgtttctatt
    36721 ttaaaacgtt ttcactaaaa aatcaagccc tttcggaaaa atagtacaaa acatgaaaaa
    36781 attttcagaa ttcagtatta aataggcaga ttattgatat taaaggtgtt ttcaagctgt
    36841 ttaaaacaaa aatatgctga aaaatgttga aattattaaa atgattttca ttttttgata
    36901 gctgttgaca gaagaaaaac caccattttc tgaaaaatag tggtttcgtt tgctactaca
    36961 agaaaagttc ttccaatttt ttggcaacac cgtcttcttc gttggaaaaa ttaagctgct
    37021 gatcagcata aggcagtagc acagggctag catttttcat agcataacca gttccagcaa
    37081 aagctagcat ctcagtgtca ttgtgttcat caccaaaggc gattaaatcc tttttatcca
    37141 tattgtaaat tccaaggaga tagttcagag cgtaagcttt attgacattc ttagacgaaa
    37201 tttcaagaat gttgagaggg cctccccaag aatcaatttc aatttcatct ttgaagaaag
    37261 cacgcatgtt tttagctaag gcatacttgt cttcgtgatg cgtttgcatc aataaggcgt
    37321 ttggatttcg agtgattttg gtaatctcta atgccatgtc ctgagtaatt tcatcaacac
    37381 caaagagttg cgggtcgata ctttctggat tggtcatggt gatgtagaca ttttttcgat
    37441 actcactggc aataaaatcc atctggaaat catcctgata ttttagtaac cttagtaggt
    37501 agcctttgtc caaagtgaca ttatgttcat aggcccattt ttgttcaggc atgtgggtca
    37561 aggccccatt aaaagtaatg attggggtct ttaaattgag ctgcagatag tagtccagtg
    37621 ccatgcggta aggacggcct gttgaaataa tgacgtggtg gcccttgtct tggacagctt
    37681 tgatggtttt ttgagtatag gtagagatgg tgttgtcatg atgtaataag gttccatcca
    37741 aatcaatggc aatcaatttt ttagtcataa ttaaattata gcaaattttg ctccaagata
    37801 aagagaaaag ataagttaag cgtattcatt agtaaaaaag ataggataac tgttttttta
    37861 atgaataaat gaagttatag acgttgaaaa gtgaacaaaa aatggtaaca tagtgttatt
    37921 gttcatttta atacgaacaa taacaataat aatgaggtgt caaaaagact tatctagtga
    37981 taagcgcttt ttgattttac ctactattta attaaggaga ctccatttca atggaaaagt
    38041 tttttaagtt aagcgaaaat gggacaactg tctcaactga gattatggct ggtttaacga
    38101 ccttttttgc catgtcctat attttgtttg ttaacccaag tattttaggt gcagcgggga
    38161 tgccctctaa tgctgtcttt ttggctacga ttatcgcagc agccatatca accttaatta
    38221 tgggactatt tgccaatgtg ccttatgcgt tggcaccagg aatgggactt aacgcttttt
    38281 tcacttatac agttgttttt gctttagggt tttcatggca agaagccttg gcaatggttt
    38341 tcatttgtgg attattcaat atttttatta ccgtaaccaa gtttcgtaaa agtatcatca
    38401 aggcgattcc agttagttta cagcatgcta ttggtggggg aattggtgtc tttgtagctt
    38461 atttaggatt taaaaacgca aatatcatta ctttttctat ctctgctgaa aatatagtaa
    38521 tggtaaatgg tgttgaaccg gctaaagcat cggctaaaac atttgcagat ggtctattat
    38581 ttgtagacgc caatggtgga gttgtaccta cgatttctag ttttacggat tccggtgtat
    38641 tacttgctat ttttggttta cttttaacga cagctcttgt gattcgaaat tttagaggtg
    38701 ctattttaat tggtattgtc gcaacaactc ttgtaggtat tcctttagga atagtggata
    38761 tgtccaacct caattttggg atcagccata ttggtgaagc ttggactgaa ttaggtacaa
    38821 ctttccttgc agctttcgat ggtttgagtt ctctttttag cgattcaagt cgtttaccgc
    38881 tagttttcat gactattttt gcttttagtc tatcagatac ttttgacaca attggtacct
    38941 ttatcggaac tggtcgtcga acaggtattt tctctcaaga cgatgagaat gctttggaaa
    39001 atagtatagg ctttagttca aaaatggatc gtgcgctttt tgcagacgct atcggtactt
    39061 ctattggggc tttggttgga acttcaaata cgactaccta tgttgaatca gcagcaggaa
    39121 ttgctgaagg tggacgtact ggactaacag cagtctccac cgcagtatgc ttcttattat
    39181 caatattgct attaccgctt gtaggtattg tcccagctgc tgctacggct ccagctttaa
    39241 ttattgtggg tgtcatgatg gtgtcttctt ttcttgatgt taattggagt aaatttgcag
    39301 atgctcttcc agcttttttt gcagctttct ttatggcgct gtgttactct atttcctatg
    39361 gtattgccgc tgcctttatt ttctattgtc tagtaaaagt tgttgaggga aaaacaaaag
    39421 atattcaccc tattatttgg ggagcaacct tcttgttcat tgtaaatttc atcatattaa
    39481 ctatcttata accaaataat ttacttattt tgctactaac tgccgcttct ttaattgatt
    39541 ttaaccttta atataaagaa gcgtttttac tttacgaata ccttattgga gtcatcttct
    39601 aggtagtgct tggaagtatg ttttttttct gatataatgt tgctatgttt tatagtgaaa
    39661 atgaatatac tcttaaagct tacggagaaa ccctaggtac ttatttgtct attggagatg
    39721 tgattgtatt gtctggcgac ttaggtgccg gtaaaacaac attggcaaaa ggtattgcta
    39781 aagggatggg gattagtcaa atgatcaaaa gcccaactta tactattgtt agagaatatg
    39841 aaggacgtct acctctttat cacttagata tttaccgtgt tggtgatgat ccagactcta
    39901 ttgatttaga tgattttctt tttggtaatg gtgttaccgt tattgagtgg ggagaattat
    39961 taggagaggg attattacaa gactatttgc aaattaccat tactaaacga gacaaaggtc
    40021 gtcaactaga cttgttggcg catggtgagc gctctcgtca gcttctggag ataatgtcac
    40081 atggttcagc aaagtctcgt tattgaagaa ggcgtacctc aagatgcaaa agctgtactt
    40141 tccttagtga cggcagctgc caaagaaaca gattttataa caggcgtaga gactatatta
    40201 gaggctactc ctcaagaatt gtcaggcttt ttatcaagaa gtcaaacctc ttttattgat
    40261 ttttgccttc tagctagatt agatgaaaaa gtagtagggc ttttaaatct ttctggggaa
    40321 gtattatccc aaggccaagc tgaagcagat gtatttatgt tagttgctaa gacttaccgt
    40381 ggttatggta tcggtcaatt attgttagag attgctcttg attgggctga agaaaaccct
    40441 tatatcgaaa gccttaagtt ggacgttcaa gtaagaaata ctaaggctat ttacctgtat
    40501 aaaaagtatg gttttcgtat tgaaagtatg cgaaaaaacg acatcaaatc aaaaaatgga
    40561 gatgacttag atgtttatca tatgcgtaaa tctgtaagtc agtaagtgaa tcgatgaaaa
    40621 ttggaaaaaa aatagtttta atgttcacag ctattgtgtt aacaactgtc ttggcattag
    40681 gtgtctatct aactagtgct tataccttct caacaggaga attatcaaag acctttaaag
    40741 atttttcgac atcttcaaag aaaagtgatg ccattaaaca aacaagagct ttttctatct
    40801 tgttgatggg tgttgataca ggctcttcag agcgtgcctc caagtgggaa ggaaacagtg
    40861 attcgatgat tttggttacg gttaatccaa agaccaagaa aacaactatg actagtttag
    40921 aacgagatac cttaaccacg ttatctggac ccaaaaataa tgaaatgaat ggtgttgaag
    40981 ctaagcttaa cgctgcttat gcagcaggtg gcgctcagat ggctattatg accgtgcaag
    41041 atcttttgaa tatcaccatt gataactatg ttcaaattaa tatgcaaggc cttattgatc
    41101 ttgtgaatgc agttggaggg attacagtta caaatgagtt tgattttcct atctcgattg
    41161 ctgaaaacga acctgaatat caagctactg ttgcgcctgg aacacacaaa attaacggtg
    41221 aacaagcttt ggtttatgct cgtatgcgtt atgatgatcc tgagggagat tatggtcgac
    41281 aaaagcgtca acgtgaagtc attcaaaagg tattgaaaaa aatccttgct cttgatagca
    41341 ttagctctta tcggaagatt ttatctgctg taagtagtaa tatgcaaacg aatatcgaaa
    41401 tctcttctcg cactatccct agtctattag gttatcgtga cgcacttaga actattaaga
    41461 cttatcaact aaaaggagaa gatgccactt tatcagatgg tggatcatac caaattgtta
    41521 cctctaatca tttgttagaa atccaaaatc gtatccgaac agaattagga cttcataagg
    41581 ttagtcaatt aaaaacaaat gctactgttt atgaaaagtt gtatgggtca actaagtctc
    41641 agacagtaaa caacaactat gactcttcag gccaggctcc atcttattct gatagtcata
    41701 gctcttacgc taattattca agtggagtag ataccggctc atcttatcag agtgctagta
    41761 cagaccagga ctatactgct tcaagccata cgccaactac gccgtcttct tcatcggatg
    41821 ctttagcagc tgatgagtct agctcatcag ggtctggatc attagttcct cctgctaata
    41881 tcaaccctca gacctaacgt tctgagggtt tttatgttta aaatatccga ttttgaatat
    41941 aaaaaagaca ggtatcaaag atgatagctg tctgtgattt caaataaagt gtatgaggga
    42001 gataatacta tctggaatgg ttgttagtta aaatgacggt ttggcaagta ggtgattcac
    42061 tagaaattag ctcactattt tcttgatatt tggccatacg attttggatt tcagtgaggt
    42121 gtgcttgtgt ctcttggtta aagtagcgcc atttatgggc caagtcccga ctaatatttt
    42181 gaattacttt tccttgactg tgaatgaggt caaggtttgc tttaatgtta tctaaatcaa
    42241 gttgggcagc atcttttgct tgtctactga tggataacag ctcttttatg gtacaacgtt
    42301 tttgatatgc tttgtaagcg gtaaaagata ataatccgac ggctatcacg gttttaactt
    42361 tcatgaacta acctcctgat tgatttgtcg ggcgagcttt tccaagacag gaaagtcagg
    42421 ctcatgagtg gtgtattgaa ttgagatacc gtcttcttca ttataacgag gaacgagatg
    42481 aacatgagca tggaaaacag tttgtcccgc taaggcttcg ttattgttaa tgatattcat
    42541 ggcagtagcg ccagtagctg actggatagc acgagcaatt ttaggaatac gagcaaagag
    42601 atgactagct gtctcagcag tcatctctag taagttacga acatgttgct taggaatgac
    42661 tagagtatgc ccttttgtag tttgtgagat atctaaaaag gcgaggacct gctcatcttc
    42721 gtagactttc gaagagggga tatccccttg aatgatgctg caaaaaatac aattttccat
    42781 tttatatcac cttctctact tgaatttgtt ataatatatt ataagtatat caaaaactag
    42841 aaagaaatta tatgttaaac attaaaaatc taacaggagg atatcacaat atccctgttt
    42901 taaacgatgt ctcattttct gtagacaatg gagagttagt cggtttgatc gggctaaatg
    42961 gtgctggaaa gtcaacaact atcaacgaaa ttattggctt tttgaagcct tatcaaggaa
    43021 gtatttctat tgatggttta actctagcag aaaatgcagt tgcctaccgt caaaaaatag
    43081 gttttatccc agaaactcct agtctctatg aagaattgac cttatcagag catatcaaca
    43141 ccgtagctat ggcttatgat atcgacttag aagtggcaca aaaacgagca caacctttct
    43201 tggaaatgtt tcgtttaact gacaaacttg aatggtttcc tgtcaatttt tctaaaggga
    43261 tgaaacaaaa agtcatgatt atttgtgcct ttgtcattga tccaagtcta tttattcttg
    43321 atgaaccatt cttagggtta gaccctttag ctatttcaga cttaatccaa acgctagaag
    43381 tcgaaaaagc aaaaggaaaa tctattttga tgagtacaca tgttttggac tctgctgaaa
    43441 gaatgtgtga tcgctttgtg attttgcatc atggacaagt tcgtgcccaa ggaactcttg
    43501 ctgacttgca agaagctttt ggtgaccgtt cagcgagctt aaatgatatc tatcttgcat
    43561 taacaaaaga ggattaagta tgaaagcatt atttctgaaa cgccgtcaag actttcaaaa
    43621 acaacaaaac aaataccttc gttacgtctt aaatgatcac tttgttttgg tgttgatgtt
    43681 tttattaggc tttgctatgg tgcagtatgg tcagctacta aaccattttc caacgaatca
    43741 tctacctatt caggtttgtc ttgggatatt gatcccatta ttgctcagta tgggatctat
    43801 agcaacgtat ctagaagagg cagatcagca tttcttactt ccaaaagaag aagaagtgat
    43861 ttcttatatc aaacaagctg agcgactctc ttttttgctt tggggaactt tgcagactgc
    43921 tgtattgctc tttttatatc ctatttttag acgtctaggt ctgtctttat ttatttttat
    43981 tatcttagtt ttgatattat tggcactaaa aagagtagtg cttagtcgaa agacaagata
    44041 ttttttgaga ggaaatcgtt tagattgggc aaaagctgtc gcatttgaaa gcaatcgcaa
    44101 gcaaagtatt ttaaagtttt attctctttt tacaacagtc aaaggaattt ctataaaagt
    44161 gaaagaaaga gcttatctaa atcctctttt aaaattagtt aagcaaactc cttcaaacct
    44221 ttggctgtcc ctttatgcta gagccttttt acgtagttca gattatttgg gcttattttt
    44281 acgactaatg ctattaagct cattatctgt attttttatc cataatcttt atttgtcagt
    44341 aagtttagca ctcattttta actatttagt tgtattccaa ttactttcac tttattatca
    44401 ctacgattac cattatatga ctagtcttta tcctgaaaat agtcggagca agaagaaaaa
    44461 tatgttaagt tttttacgag gtttaagctt tttaatgtta atcgtcaata tgctgtgttg
    44521 ctcatcagcg cccaaagcac tcattttgat tgtaggtatg gttttcatag cttgtatata
    44581 tctaccttat aagttaaaga agatcattga ctaagtagcc taaaacaagt aaaatagggg
    44641 taaacgacta taaaagatag aaaaggaggg cgataaggtg acaacgacgg aacaagaact
    44701 taccttgact cccttacgtg ggaaaagtgg caaagcttat aaaggcactt atccaaatgg
    44761 ggaatgtgtc tttataaaat taaatacgac ccctattcta cctgccttag caaaagaaca
    44821 gattgcgcca cagttacttt gggccaaacg catgggcaat ggtgatatga tgagtgccca
    44881 agaatggctt aacggccgta cattgaccaa agaagatatg aacagtaagc aaatcattca
    44941 tattctattg cgccttcaca aatctaaaaa attagtcaat caactgcttc agctcaatta
    45001 taagattgaa aacccatacg atttattggt tgattttgag caaaatgcac ccttgcaaat
    45061 tcagcaaaat tcatacttac aagctatcgt taaagaatta aaacggagct taccagagtt
    45121 caaatcagaa gtagcaacga ttgtgcatgg agatattaaa catagcaatt gggtgattac
    45181 tactagtggt atgatttttt tagtagattg ggattctgtt cgtctgactg atcggatgta
    45241 tgatgttgct tacctgttga gccactatat tccacggtct cgttggtcag aatggctgtc
    45301 ttattatggc tataaaaata atgacaaggt tatgcaaaaa attatttggt atggtcaatt
    45361 ttctcacctg acacaaattc tcaagtgttt tgacaagcgt gacatggagc atgtgaatca
    45421 ggagatttat gccctcagaa aatttagaga aatatttaga aagaaataat gcgagttaga
    45481 aaacgaaaag gtgctgagga gcacttagct aataacccac actatgtgat attaaatcca
    45541 gaagatgcca agggccgttg gcatgacgtt tttggaaatg accgtcccat tcatatcgaa
    45601 gttggttcag gaaagggcgg atttatcaca gggatggcct tgaaaaatcc tgatattaac
    45661 tacattggca ttgatattca attatctgtc ctaagctacg ccttggataa ggtattagct
    45721 tcagaagtac ccaatgtcaa acttctgcga gtggatggat caagtttaac caactatttt
    45781 gaagatggtg aggtggatat gatgtatctc aacttttcag atccttggcc aaaaaccaag
    45841 catgaaaaac gtcgtttgac ctacaaggat ttcttagaca cttacaagcg tatcttgcca
    45901 gaacacggtg aaattcattt taaaaccgat aatcggggct tgtttgagta cagtttagct
    45961 agtttttctc aatacggcat gaccttgaga cagatctggc ttgacttaca cgctagtaac
    46021 tacgaaggaa atgtcatgac agaatacgaa gagaagttct ttaataaagg tcaagtcatt
    46081 taccgagttg aggcaaattt ctagtagtat tttgtttcaa aatatgataa cataaaggag
    46141 ttgatgcagt attaacttct ttagtaatgg agaggtcgca tagtggctta gtgcgcacgc
    46201 ttggaaagcg tgtagtcctt aacggggctc gggggttcga atcccctcct ctccttgtga
    46261 gtaaaacaaa gtgcatatcc ttgcattcct cttaaattat ggtataatag gcttaaataa
    46321 tacagaaagg tggtgggata tgtctcacca cttttgtatt aagtggattc ccaaggacca
    46381 attatcttag agaagagcat aaaaatagag gaggtaatca aaatagcaaa tacatctatt
    46441 atcgatatcg taaccaagac agtaacacct gagattaagg caccttatga attagtagac
    46501 gttgagtatg acaaaatggg tagtgactac atccttagta ttttagtcga taaggaaggt
    46561 ggaatcacag tggaagatac atctgacttg acgaatatta ttagtccgct gttagatacg
    46621 attgatccag atccttttcc aaaccaatat atgctagaag tctctagtcc aggtttggag
    46681 cgtccgctca agacagctga cagtttaaaa gcagcagttg gctcttatat caatgtgagt
    46741 ctttatcaag ctattgataa ggtgaaagtt tttcaaggag acttattagc ctttgatggt
    46801 gaaacgttga ccattgatta tcttgataaa acacgtcata agatcgtgaa tataccatat
    46861 caagcagttg ctaaggtgag aatggctgtc aaattataac ttttatttca aagcactaaa
    46921 cttttttagg aacgcttaag caaatttgaa acaacaccta tagagtttat acaagctaaa
    46981 caaaaggaat taagggagcc tttagggggc tattgatcgt attaatttaa gaaaggattt
    47041 ttgccaagct ttacaagcaa ggtagataac attatgagca aagaaatgct agaagccttc
    47101 cgtattttgg aagaagaaaa acacattgat aaagcagata ttattgacgc agtgacagaa
    47161 tcattaaagt ctgcctataa acgtcgctat ggtcaatcag aatcatgtgt tattgaattt
    47221 aatgaaaaaa cagctgattt tcaagtattc acggttcgtg aggttgttga agaagttttt
    47281 gacagccggc ttgagattag tttgaaagat gctcttgcta tcagttctgc ctatgaattg
    47341 ggtgataaga ttcgctttga ggaatctgtc aatgaatttg gacgtgtcgc agctcaatca
    47401 gctaagcaga ctattatgga aaagatgcgc cgccaaatgc gtgaagtgat gttcaatgaa
    47461 tacaaagagc atgaaggtga aattatgaca ggaacagttg aacggtttga tcaacgtttt
    47521 atttatgtca atcttggttc cttagaagca caattgtctc accaagacca gattccaggt
    47581 gaaactttca aatcacatga ccgtattgac gtttatgtct acaaagttga aaataatcct
    47641 aaaggagtta acgtctttgt tagtcgtagc catccagaat tcatcaaacg tattatggag
    47701 caagaaattc ctgaagtctt tgatggtact gttgaaatca tgagtgtctc tcgtgaagca
    47761 ggtgaccgta ccaaggttgc tgtgcgcagt cataatccta acgttgatgc catcggaaca
    47821 attgttggac gtggtggaag taatattaaa aaggtcatca gcaagttcca tccaaaacgt
    47881 gtagatgcta agacggggct tgaaattcca gttgaagaaa atattgacgt gattcaatgg
    47941 gtagatgatc cagctgagtt catctacaat gccattgctc cggctgaagt agacatggta
    48001 ctttttgacg atgaagatct taaacgtgct acggtagtag ttcctgatag caaattatca
    48061 ttagctatcg ggcgtcgcgg ccaaaacgtt cgtttagcgg cacatttgac tggctaccgt
    48121 attgatatca aatcagctag cgaatatgat cgtcttgagg cggaaaaaga agcagcaaca
    48181 gttgtggaag agccagttgt tgacgatgtt atgactgccg aggaagtgta agaaaagagg
    48241 tgtttgatgt ctaaagtcaa aaaaatacct ttacgaaaat cacttgtttc tggtgaaatt
    48301 attgctaaac gagatcttct taggattgta aaaactaagg atggtcaagt tttcattgat
    48361 ccaactggta aacaaaatgg tcgtggtgct tatatcaaat tagacaatca agaggcctta
    48421 atggccaaga aaaaacaagt tttcaacagg agtttctcaa tggacattcc agaaagtttt
    48481 tacgatgact tgattgctta tgttgatcac aaaatcaaaa gaagagagtt aggtcttgac
    48541 taatttagaa agattatcta gtcttattgg tctagctcaa cgggctggaa aagtgatttc
    48601 aggtgaagaa ctagtagtaa aagctattca acaccagcag gtaatattag tatttttagc
    48661 caatgatgct ggtcctaatg tgacaaaaaa agtgacagat aaaagtaatt attataatgt
    48721 agaagtctcc acagtgttga atgcactgga attaagtgct gcactaggta aaccaaggaa
    48781 ggttgctgcc gttgcagatg ctggattttc aaagaaaatg aggactctta tggaatagat
    48841 gaataggagg acacaaattg tcaaagaaaa gattacatga aattgccaag gaaattggta
    48901 aaagtagtaa agaggtggtt gaacacgcta aatacttagg attagatgtg aaaagccatg
    48961 catcaagtgt tgaagaagcg gatgcgaaaa agattatttc aagtttttca aaggcttcta
    49021 aacctgatgt gacagcttct caaacagtca agcccaaaga agttgctcaa ccctctgtaa
    49081 cagtggtcaa agaaacaggt tctgagcatg tagagaaaac acaggtctct aagccaaaga
    49141 gtcgtaattt taaagctgaa agagaggctc gtgcaaagga acaggctgct cgaaaacaag
    49201 caaatggctc ttctcatcgt tctcaagaac gtcgaggagg ttatcgccag cccaataatc
    49261 atcaaactaa cgaacaagga gataagagga ttacccatcg ttctcaaggt gatacaaacg
    49321 ataagcgtat tgagcgaaaa gcatcgaatg tatcacctag acatgataat catcagctag
    49381 ttggtgatcg taaccgttcc tttgctaagg agaatcacaa gaatggtcga ttcacaaacc
    49441 agaaaaagca aggacgacaa gagcctcaat cgaaaagtcc taaaattgat ttcaaagctc
    49501 gtgctgctgc cttaaaagct gaacaaaatg ctgaatactc acgccaaagt gaaacacgtt
    49561 ttcgtgcaca gcaagaagct aagcgtttag ctgagttggc aagacaagaa gctaaagaag
    49621 cggctttaaa agcacaagct gaggagatga gccatcgtga agcagcactg aaatctattg
    49681 aagaagcaga aactaaatta aagtcatcaa atattagtgc taaatctact gctgataatc
    49741 gccgtaaaaa acaagcacgt cctgaaaaga atcgtgagtt aactcatcat tcacaagaag
    49801 gacaaaagaa aaataagaag agttggaata gtcaaaacca agtgagaaat caaaaaaata
    49861 gtaactggaa taaaaataaa aagaccaaaa aaggcaaaaa tgttaagaat actaacaccg
    49921 ctccaaaacc agtaaccgag cgtaaattcc atgaattgcc aaaagaattt gaatatactg
    49981 aaggcatgac agttgccgaa atcgcaaaac gtatcaaacg cgaacccgct gaaattgtta
    50041 aaaagctgtt tatgatgggt gttatggcaa ctcaaaacca gtctttagat ggggatacta
    50101 tcgaattatt gatggtagat tatggtattg aggctaaggc taaggtagaa gtagatgatg
    50161 ctgatatcga gcgcttcttt gaggatgaaa attacctcaa tcctgaaaat attgtagaac
    50221 gcgcacctgt tgtaactatc atgggacacg tagaccacgg taagacaact ttgcttgata
    50281 ctttgcgtaa ctcacgtgtg gcaacaggag aagctggagg aattactcag catattggtg
    50341 cttaccagat tgaagaagct ggcaagaaaa ttaccttctt ggatactccc ggacacgcgg
    50401 cctttacaag catgcgcgca cgtggagctt ccgttaccga tatcaccatt ttgattgttg
    50461 cagctgatga tggtgttatg ccacaaacga ttgaagcgat caatcactca aaagctgctg
    50521 gtgttccaat tattgttgct atcaacaaaa ttgataaacc aggtgctaat ccagaacgtg
    50581 ttatcgcaga attggcagaa tatggtatca tctcaactgc ttggggcgga gagtgcgaat
    50641 ttgtagagat atctgctaaa tttaataaaa atattgatga actattagaa acagtccttt
    50701 tggttgctga agtagaagaa ttgaaagctg atccgacggt tcgtgctatt ggtactgtga
    50761 ttgaagcacg cttagataaa ggtaaaggtg ctatcgctac gcttcttgtc caacaaggaa
    50821 ctcttcatgt tcaagaccca atcgttgttg gtaatacctt tggtcgtgtc cgtgccatgg
    50881 taaatgacct tgggcgtcgt gttaaatctg cggagccatc aacaccagtt tccattactg
    50941 gtttgaacga aacaccaatg gctggtgatc actttgctgt ttacgctgat gaaaaagctg
    51001 cgcgtgcagc tggtgaggag cgatcaaaac gtgccctcct caaacaacgt caaaatacac
    51061 agcgtgttag ccttgataat ctctttgata cccttaaagc aggagaaatc aagactgtta
    51121 atgtcatcat caaagcagac gttcaaggtt ctgttgaagc ccttgcagca tctcttgtaa
    51181 agattgaagt ggaaggtgtc cgtgtcaatg tcgttcactc tgctgtaggt gctatcaatg
    51241 agtctgatgt gacccttgct gaagcatcaa atgctgttat tatcggtttc aacgttcgcc
    51301 ctaccccaca agctcgtcaa caagcagata cggatgatgt ggaaattcgt cttcatagca
    51361 ttatctataa agtcattgaa gaagtagaag aagccatgaa agggaaactt gaccctgttt
    51421 accaagaaaa aattcttggt gaagccatta ttcgtgaaac cttcaaagtt tctaaagtgg
    51481 gaacaattgg tggctttatg gtaatcaacg gtaaggtgac acgtgattcg agtgttcgtg
    51541 ttatccgtga tagtgtcgtt atttttgatg gtaaactggc cagcttgaaa cattacaaag
    51601 atgacgttaa agaagtcggt aatgctcaag aaggtgggtt gatgattgaa aactttaacg
    51661 atcttaaagt tgacgatact attgaagcct atattatgga agaaattgtg agaaaatagg
    51721 ggctaagaag gtctgagatg tgacgttttt cctctgtcgg aaataatgac ttgttctacc
    51781 agatgagcta cttggggcat tccttccagt ctcgtcatgg aattctcaga ttccctttag
    51841 ttgtcgttat caaaacaggt agcaatgtca taagctgggc tttcagccta gcttttgttt
    51901 taaaaatgtg gaaaggaaat ggctatggct aatcatcgta ttgaccgcgt tgggatggaa
    51961 atcaagcgcg aagtaaatga tattcttcag aaaaaagtgc gtgatccacg cgttcaggga
    52021 gtaacgatta cagaagtgca aatgcagggt gacttgtcac ttgctaaagt ttattacact
    52081 attatgagtg acttggcatc tgataatcaa aaagcacaaa cagggcttga aaaagcgact
    52141 ggaacgatta aacgtgaact tggcaaacaa ttgaccatgt acaaaattcc agatttggtg
    52201 tttgaaaaag acaattccat cgcctatggt aataaaatag atcaactgtt acgtgagctt
    52261 gataaaaaag attaaattaa aaacctttaa ggtatcttat tagagtcacc ttaagggttt
    52321 tttgttttta gtaagctttt tgaatcgtat caatgatttg atattgtgca gtcttggctt
    52381 cttcaattgg atagattggg taaacatgat tcattttatc agcgacgata agttcatgtt
    52441 gatgaccttt ggcagttaat atatcatcaa atttcttaac atctgggtag aaaatttcat
    52501 gtgtaccaac aaacatagta ataggtgcta gccctgatac atctccatta attggactaa
    52561 catatggatg tttggtgttg tttgggtcac ggcgtgccca aatttcccca actttacgta
    52621 ggccccaagc tgaaagaatg ggatcattac tttcatagct ctcaatatct ggatttgaca
    52681 tggttacatc taaccatggt gataagagaa caatgtcttt tggttgtttt aaactttcat
    52741 tttttagggc taatgctaaa ccaagcgcta gtccaccacc tgctgaatca cccataatag
    52801 tgatattttg tgcagttgtt tctttaagag tatctctgta aaggtcaacc aattttggca
    52861 tagcatcact gtaagagtaa gtaggtgctt ttggatagat tggtaagata atcttagcat
    52921 caagactagt tgataaggtt tttagcatgt cgatatgata agtagttggg ttgtttaggt
    52981 aagagccccc atgtaaatag aaaatgacct tttgattggc tttattgctg gggttctcat
    53041 tccaagtatg aacttgcata ttatcaacag ttttagtgac taatgtgcca tttacctgtt
    53101 cttctttaag atcaaagcct ttatttgaag cttctccagc agagttgaca tattgatcaa
    53161 acttagtttc gtcttgctct gaataatagc ctttgtctcc ttttaaccaa aagtatttct
    53221 ctataaacca gcttttccaa gatctagaac tggcatcaac ttgagtgcta gctcctattg
    53281 ctagagtaag tcctagtaaa ataagagtgc ttttaagtgt ctttttcaat gagttctcct
    53341 tattattatc atttttttat catataatca tatcataaat gaaaaaattg tcaacttaag
    53401 aaataaaatc attagaaact ttatatattt acaaatgtag ataaatatga tataatatat
    53461 ctacaaatgt agattaaaag gttgtgagtt gatgaatcaa aatatttcag ctgccgaatg
    53521 ggaagtcatg cgtgtggtgt gggccagtgg tgatattaaa agtagtgata ttattactat
    53581 tttaaggaaa aaatatcaat ggtcagattc taccattaaa accttgattg ggcgtttggt
    53641 ggaaaaaaag gctttgggaa cttaccggca aggaagagct tatatttatc aagctctttt
    53701 ggatgagact ttgctacaaa aagaagcact agcgactgtt ttagacggta tttgtcagcg
    53761 gcaacacacg cgtctacttc ttgaacggct ttatgactta ccgatgacct tagaggaaat
    53821 tgaggcattc caagagctac tagaagtcaa aaaagaaaat gcagttcttg aggtgccgtg
    53881 taattgcctg cctgggcagt gccactgtca gaaaaaggag acgtattaat ggctaaagag
    53941 atatttttag tggagggaat gagttgtgcc tcttgtgctc taacaattga aaaaacggtc
    54001 aatcaattgc ctgaagtaga acaggctgtt gtgaatttag cgaccgagaa actcacggtt
    54061 acttatcaag atgacgattt agaaacggcc aaagttattc aagcggtaaa agctgctggt
    54121 tatggtgcac aagtctttga tgaacatgca aaacacatgc aaacaggtcg tcgtgacgaa
    54181 gacctaaagg ttatttggtc tcaggtcttg tggtctgccc tattcaccat tcctatatta
    54241 tacctagcta tgggtcacat ggtgggctta tggcttcctt catttctgca accagatcgc
    54301 tatcctttcg tttacagctt tagtcagcta ctcttgacga ttccagtctt agtattaaat
    54361 cgtcattatt accataatgg gttcaaagct ttgttcaagg gacatcctaa tatggactcc
    54421 ttggtagctt tagcaaccag ctttgctttt gcttatagtc tttatggagt ggttgaaatc
    54481 agtctgggcc gggcgcactt tgtgcactcc ctttattttg aatcggtggt agtgattttg
    54541 acactcattg gtctaggaaa gtattttgaa agtcgttcta agggccgtac ttatcaagct
    54601 attcaaaagc tcctatcctt gaaggctact gatgtgaggg tatggagaaa cagccaatgg
    54661 caattgttgc cgttagaaga gattagctat gatgaccttg tcctggttca accaggtgaa
    54721 aaagtttcta ttgacggcat tatcgtggaa ggacatagca gtttggatga atccttttta
    54781 actggggaaa gtttgcctgt tgaaaaggga gaaaaagata atgtctttgc gggcagcttg
    54841 aatggtcaag gcgccctcac gattaaacca gataagcttg ggaatgatac cttgttagca
    54901 caaattatcc aactagttga gaatgctcaa gaaaataaag cacctattgc agccattgct
    54961 gatagagtct caggtgtctt tgttccggtg gttttggtat tagctctgtt aacaggggtg
    55021 ttttggttgg tattcatgca ggaaagtctt cgttttagtt tgacaacagc catcgctgtt
    55081 ctagtcattg cttgtccttg tgcgcttggt ttagcaaccc cgacagcgat tatggttgga
    55141 acagggcgtg cagctgaaaa tggtgttctt tttaaaggtg gtgacatctt agaacaagcc
    55201 catcaggtag atacggttgt ttttgataaa acggggacga ttacggaggg gaaaccaagt
    55261 cttcaaaacc tcctaacttt ttcgggagat gatcacctta tcttgcaaga agctgcttcc
    55321 ttggaggcct attctcaaca ccccttaggg gaggctattg tccgtgctgc tcaggaagct
    55381 ggttacgata gtctaccagt ggaagagttt gagtctttaa ccggcctagg agtcactggt
    55441 cagcttgaag ggcgtcgttt ggcgattgga aatgctactt taatggcaac ccttggtatt
    55501 gatttagctt ctgttcagtc agtttgtgct aaggcttcag ggaaaggtca aacccttgta
    55561 tattatgcta aagaggggca gctaagagct cttttcagta ttgctgacgc tgtcaaagaa
    55621 gatagtcaag ctaccgtcga agctttgcag caactgggaa ttcacaccat catgctaaca
    55681 ggtgaccacg atgctaccgc taaggctatt gcctctcaag tggggattac agatgtgatc
    55741 agtcaagtct tacctgatca aaaagcaggc gtgataacaa acctccaatc tcaagggaga
    55801 aaagttgcaa tggtaggtga tggtattaat gatgctccgg cattggctgt agcagacatt
    55861 gggatagcta tggggtcagg gacagatatt gccattgaat cggcggatgt gattctgatg
    55921 aaacctgata tgctggattt ggtgaaagct atgtcattga gtcgagcgac tatgaggatt
    55981 gtcaaggaaa atttattttg ggcattcata tacaatgtcc tcatgattcc agtggccatg
    56041 ggcttacttc atctttttgg aggtccacta ttgaacccga tgttagcagg ttttgccatg
    56101 agttttagtt cagtatcagt tgttttgaat gccctgcgat taaaaggaaa aaccatttga
    56161 aggagaaaac gaaatggaaa aacactatca ggttacagga atgacgtgtg acggttgtgc
    56221 aagaacggtt actgaaaaat tatcagctgt ccccggtgtg caatcggtcc aggtaaattt
    56281 ggaaaaagga gaggctaagg tgacaggacg tcctttaact ttcctactca agcgtgcttt
    56341 gaaggatacc aaatttgaat tacataaatg gtcttaggtt attttggtag ccttacttca
    56401 tctcaaaaga ggttccagtt ttttaatctg ggcttctttt tttgtggtca ctcataaaga
    56461 ctctgacgtt agcaggtgtg ttccgagcaa aacaaaaaca cctctctggg ggcaaatcac
    56521 ttttgccaga aggtgtttaa ggacgatgcg ctgacaggct gtccattctt gatgaaacgg
    56581 ttactccttg ttttcgtggg ctactaataa ttgtgtggac tgactataac gttcgatgac
    56641 gtcctcagtt atttgcgaat ctgtaacaac agcatcaatg ttgtttaaat ggtaaaaaat
    56701 gaagaagtcg taggcattga atttttggtt atctaccaag aggtattttt caatagaatt
    56761 attaaaagct agcttttgaa tctctccttc agtttcgcta taagttgcaa tatcgttttt
    56821 ataaatgcca ttacagctaa taaaagcctt ggcaaatttt aaggatgaga tattttgact
    56881 agcaagggac cctacaaaag ctcctgtaat agatcggtat tcaccaccga taagaatcag
    56941 gtcaatggtt tcgctgtcct gaaggatgtt aaagacaggg aggctattgg tcacaatgcg
    57001 aatctgacga ttttttaatt gctcagcgaa acattctaaa gttgttcctg gaccaataaa
    57061 gattgtttca ccatcattga ctagttgtgt cgcatatgaa gctagttccc atttttcctt
    57121 tgtttgaacg gtttgttttt caatatttga ccgctctttt ttattaggca tggtaatact
    57181 ttgtgcacct ccatggatgc ggatcaattt gccggctttt tccagttcat ctaagtctct
    57241 acgaactgtc atatcagaaa cgtttaaagt ctgaataata tcattcacag taacaatacc
    57301 ttgctcattg actatttcgg taatttttag aagtctttct ctttttaaca tctaaggggc
    57361 tcctttctat agtttattta cttatgttta tcatagcata tagaccttca tatttcaata
    57421 aaacaaaata aacaaaacaa aaacaaacat atagaacaaa aaatattgcg taaaaatgtt
    57481 gaattatgtt gaaggttata ctataatgat tttgtaaacg gttaccaatt tgttgatgat
    57541 gagatgacag ttgttaaaaa ttgatactta tagaaaggcg gtagggagtg tttcctaata
    57601 ttctatttac tgaagcaagg acgcagccag agttttttga tcttgttgct agccacttgg
    57661 aaaaggttgg gtatgtgacg caagagtacc atcaggcttt agtggagcgt gaggcggtat
    57721 ttccgacagg actcaaagtg gacctcaaag atgggtcaga tattttgtat gcggctattc
    57781 cgcatacaga aaccaagtat tgcttggttg atcaagtggt ctatgttaga aatagtcaag
    57841 cccttacctt taagcacatg attaatccag aggaagactg tttggtaacg gatttcttct
    57901 ttattatcaa tagtcaaaac gagggtcaaa cgatgattct atccaatctc attaccttct
    57961 ttattacgaa aggcaatctt agctatctag ccagtctaaa agatgataaa caagctattt
    58021 caaactattt aatagaaaaa ggagtgtttc agcatgatta aaattctagc agcctgcggt
    58081 gcaggggtta actcaagcca tcaaattaaa gatgcgattg aaactcagat gagtgaccgt
    58141 ggttacgatg ttcactgtga tgcggtgatg gtcaaagaca tcacagaaga attggtgtct
    58201 cgttatgata tttttacgcc gattgcaaaa actgacttgg gatttgagat gccaattccc
    58261 atagtagaag caggaccgat tctctatcgt atcccaatca tgagtgagcc tgtttttgct
    58321 gaattagagc gcgtgattaa agaaaatcat ttgcagtgag ttaataaaaa cataaggaga
    58381 caagatgatg caaccttttt tagacattat taacaagatt ctgggatttc ctattcagtt
    58441 gggatcaggt gtggtcatgc tgattgtcat gacaggttta gccatgattt tcggggttaa
    58501 attcacaaag gcactggaag gcgggattaa gttagctatc gctcttacag gtattggagc
    58561 cattattggg attttgacgg gggctttttc agagtcttta caggcctttg ttaaaaatac
    58621 agggatcagt ttaaacatta ttgatgtcgg ttgggcaccg cttgcaacaa ttacctgggg
    58681 ttccccttat accctttatt tcttgctggt gatgctggtg gttaatattg tcatgattgt
    58741 catgaaaaaa acggacaccc ttgatgtcga tatttttgat atttggcatt tgtctatcac
    58801 aggtctattg attatgtggt atgctgatca caaccatttg ccagtccttg tgtctctttt
    58861 gattgctact gtggcagtta ttcttgttgg ggtattgaaa atcattaact ctgatttgat
    58921 gaaaccgacc tttgatgatc ttcttgggac agggtctcaa tcaccaatga cttcaactca
    58981 catgaactac atgatgaatc caatcattat ggtcttagat aagatttttg acaaggtctt
    59041 tccggggctg gataaatatg actttgatgc tgctaaattg aacaaaaaaa ttggcttctg
    59101 gggctctaag ttctttatcg gaatggctct aggttttgtg attgggatta tgggagatcc
    59161 tcatttcact gttgaatcta tcaaaaattg gtttggtcta ggatttacag ctggtgcctg
    59221 cttggaactt ttctctttga ttggctcttg gtttatcgca gctgttgagc ctttgtcaca
    59281 agggattacc aattttgcca atgctagaat gcatgggcgt cgtttcaata tcggtttgga
    59341 ctggcctttc attgctggtc gcgctgaaat ctgggcctgt gccaatattc ttgctccaat
    59401 catgttgatt gaagccgttc tcctatcaaa agttggcaat gggattttac cattggcggg
    59461 aattattgct atggggatga caccagctct tcttgtggtc acacgtggtc gtttgattcg
    59521 catgattatt tttggttccc tcttattgcc attattcctc ttgtcaggaa ctatgattgc
    59581 tccatttgcg acagagttgg ctaaaaaagt aggggctttt ccagcaggta caagcgctgg
    59641 ttccttgatt acgcattcaa cacttgaagg accaatggaa aaaatctttg gttatgtgat
    59701 tggtcaagcg acaacaggtc agattgtctc aatcatcacg ctaatcatct ttattgccat
    59761 ttacctaggt ctctttgctt ggtatgctaa ccaaatgaag gcacgtaacg ctgagtatgc
    59821 gaaaacaatg aaataaaatc aggtcaagtg actgactaaa aaattaggga gaatagcaga
    59881 taaccgctta aggtattcct gccttatccc ctaacgtgaa aagagtattt ctcatgtaag
    59941 gcaaggcgct ctgtgggaac ccacaagtgc tttgtcttga aagaaataat ggaagacaac
    60001 taagactgct ggcaatcatc ttgatctaag gacaggtaat catgtccccc ttctctagat
    60061 tggcaagcgt tttgggttag aaaaggaaaa gctatggcta ttattttagg tgcagatgca
    60121 cacggaaatg cattaaaaga attgatcaaa agttttcttc aagaagaagg ctatgacatt
    60181 attgacgtga ctgatattaa cagtgatttt attgataaca cattagcggt ggctaaagcc
    60241 gttaatgaag cagaaggtcg tttaggcatt atggtggatg cttacggagc aggtcccttt
    60301 atggtagcca caaaactaaa aggaatggtt gctgctgaag tgtcagatga acgctctgct
    60361 tacatgacgc gcggtcacaa caatgcccgc atgatcacaa taggggcaga gattgtaggt
    60421 ccagaattag cgaagaatat cgtcaaaggt tttgtgactg gtccctacga tggtggtcgt
    60481 catcaaattc gtgttgacat gctcaataaa atggcctaaa ggaggataaa gtgatgaaaa
    60541 ttgcgattgg ttgtgaccat attgtcacca acgaaaaaat ggctgtttct gattttttga
    60601 aatctaaagg ctatgacgtt attgactgtg gcacttatga ccatacaaga acccattacc
    60661 ctatttttgg aaaaaaagtc ggcgaagctg tggttaatgg tcaagcagac ttgggtgttt
    60721 gtatttgtgg aactggagtt ggcattaata atgccgtgaa caaggtacca ggtattcgtt
    60781 cagcccttgt tagagatatg acaacagcgc tttatgccaa ggaagaattg aatgccaatg
    60841 tgattggctt tggtggtaaa atcactggtg aacttcttat gtgtgatatt atagatgctt
    60901 ttattaaggc agaatacaaa gaaactgaag agaataagaa gctaattgct aaaatagccc
    60961 acttggaaac tcatcatgct aaccaagaag atcctgattt ctttacagaa tttttagaaa
    61021 aatgggaccg tggtgagtat cacgattagg aagaagagat gagtttaaca gttaccttaa
    61081 atccttctgt cgctatttcc tatcctttag attgtctggc tatggacacg gttaatcgtg
    61141 ttgacagaac ggcaaaaaca gatggtgata aggagctaaa tgtgaccaga atgttagcaa
    61201 aagctggtca gttatggcaa caggatttag tggtggtaaa ctgggtgact ttatcattca
    61261 tcagttacaa gaacagggca tttctaacca atttttcaaa atcaaagggg aaacgagaaa
    61321 ttgtattgct gttttacatg aaggcatgca gacaaaaatt ttggaagctg gtccctacag
    61381 tgatgtggac gaagccgaag tctctttgag ccacatgagt actattgcta agccgtttga
    61441 tgtcttaact tctcaggcag tctgcctaag agactagcta ctcactatta tcaagatttg
    61501 atgactatgg caacttttaa acaattatat cagcaacttc aagtaagaga ggtatcacat
    61561 gacaatcaca gcaaataaaa gacattactt agaaaaagtg agccatcaag gaatcatatc
    61621 agctttagct tttgatcaac gaggtgcact gaagcaaatg atggcagcac atcaagaagg
    61681 agaagcgaca gttacacaga tagaaacatt gaaagttctc gtttctgagg aattgacgcc
    61741 ttatgcttca tctattttat tagatccaga atatgggttg ctggctacta aggtaagagc
    61801 taatcagaca ggcttactgt tagcttacga aaaaacaggt tatgatgcta caaccactag
    61861 tcgtttaccc gattgcttag tggaatggtc ggtcaaacgg ttgaaagcag caggtgcaga
    61921 tgctattaaa tttttgctct attatgatgt tgatggagat gaacaaatca atttacaaaa
    61981 acaagcttat attgaacgca ttggttcaga atgtacagct gaagacattc ctttttttct
    62041 tgaacttttg agttatgatg agagaatatc agataacaac agtgcggcat acgcaaagct
    62101 taagccacat aaggttaacg gtgctatgtc agtattttcg gataagcgtt ttggcgttga
    62161 tgtgctaaaa gtagaggttc ctgttaatat ggcttatgta gaaggtttta ctgaagggga
    62221 agtccattac agtcaagctg aggctattaa agcttttcaa gaccaagaag ctgccagcca
    62281 cctcccttat atctatttga gtgcaggcgt atctgccaaa ctttttcaag agacattata
    62341 ctttgcagca gcagcaggtg ctcaatttag cggtgttttg tgtgggcgtg ccacgtgggc
    62401 aggatccgtt ccagtttata ttactaaagg agaggacgaa gcaagaaagt ggctatgcac
    62461 tgaaggcttc caaaatattg acgagttaaa cagggtactc gaagagacag ctagcccttg
    62521 gacggaaaaa atctaaaaca accttatcct atcaagcagc tctcattgat gtgataagat
    62581 aagtatgggg ataattgttt gaatcttttg tagcaaggat gaaaatgggt tttatccttg
    62641 cttttttatc cttacatttt atctttttct acttattttt taaaggaaaa cgtggtaaac
    62701 taaaagaaga ctaaaagaca atagggtagc ttatgacaat tgatatgtgg gaaattttaa
    62761 atatcatcgg gaccattgcc tttgctcttt caggtgctat tgttgccatg gaagaagaat
    62821 ttgatatttt agggattttt attttaggtt tcgtgacagc ctttggaggc ggagccattc
    62881 gaaacaccct aattggttta cctatagagg ccttatgggg gcaaaagcca gaattcactt
    62941 gcgctttctt tgctatggtt ttgattatgc tttttcctaa gctaatagct agaggttggg
    63001 tacgggcagc tgttttgact gatgccattg gtctggcagc ttttagtgtc caaggagcct
    63061 tgcatgctgt ccgtcttaac cagcctttaa gtgctgtcat tgtagcagct gtgttgactg
    63121 gtgcaggcgg tggtgttgtc agagatattc tggcagggcg aaaacctagt gttttgcgta
    63181 gtgaaatcta tgctgggtgg tctattcttg cagctattgt tttgcatttt aaactagcag
    63241 attcaacgat tgaatgttat gccttggttg ttttactcac gactttacgc atgattggca
    63301 accgtaaaaa atggaacctc cctaaaatca aatggaaaga gaagagatag gatgattcaa
    63361 ctaattgcaa ttgatttgga cggcacctta ttaaaccagg acaaacagat tccaaaagag
    63421 aatatcacag ccatccaaga agcagctcag tcaggcttaa aaattgtctt atgcacaggc
    63481 cggcctcagt cagggacaag accctatttt gaccaattag atttgacaca agaggaattc
    63541 ctcattatca ataatggctg tagtacttat agtagtcctg actggcaatt acgccattca
    63601 aaaatgttga aggtttcaga tattgaattg ctggaagagc taagccaaag ctttccagat
    63661 atttacctga ctttaactga ggaaaacgat tatttggtgc ttgaagaaga agtgccagac
    63721 cttgtgcagg aagatggaga tttggtattt accattgtca agcctgtctc cttagcagag
    63781 ctgtcggaca ctcctcgcct gatttttcaa gccatgtact taggagaaaa agctgcgcta
    63841 gatgcctttg aacgtgcggt gagaaatcag cttagtcaga gtttccatgt tgttcgtagc
    63901 caagataata ttttagaaat tctccctcgg ggagtcagca aggcatcggc tctcaaagaa
    63961 ttagtagaag atttgggttt aactgctgac caagtgatgg ctattgggga tgctcccaat
    64021 gacattgaga tgttaactta tgctggttta ggagttgcta tggaaaatgc ttcagcagct
    64081 atcaagccat tagctgacaa agtcactttg actaatgata tggcgggtgt ggcccaggct
    64141 atccgtcagt ttgcacttgc agctcaaaaa gactaactat tatataaaaa aaggttccca
    64201 aaaggaacct ttttacgtta atagaggcaa gcccatagca gccatttctt cggcaggaac
    64261 gatcatgtca tctgaaatcc agtttgtcaa gacagaaaca atagcattgc tccaaaaaag
    64321 gcgcttatag tgcgattgtt ttttgtcttt taatttttga taagctttca gacgtttagt
    64381 gactaatcgt gttagaagat ggtgcaggtg atgtttgaaa atcattttaa gaagctgagc
    64441 ttctttttta gcttcagtaa aaagatagag ccaggcttga taagcctgag ttttaatatc
    64501 aaattgtttt agtccacgaa aaatacgacg gataacccct actaacagtt gttctataat
    64561 ggcttcttta gaggtataat tacgataaaa agcgttacga gatactcctg ctttcgtcac
    64621 caattctgaa atcgtaatat cacctaaagg ttttgttttt agaagattta gtaaggcgat
    64681 ttccatagat tcacgtgcta tgcgtcgtgt ttctttatta aattgtgtta agttttgaag
    64741 tgatcttttt gagagtgctt tatcagtcat cacaaatacc tttcaagtgt tacatctgat
    64801 gagttatcag tagcaaaaac cgacttaata atgatataat tttatgggaa aagtcttagt
    64861 ttgtcaacta aagttagtta tcaggagcct cattacctcc ctgtatagct ctattggatg
    64921 actttactaa ctattgaaaa ggctagtaat aaaacatagg atttaatgac tagttattac
    64981 cattagccta gacatcttag cgaaggctta ataatctggt ctttgttacc gaacacaaat
    65041 tagagaaaaa gaaggataaa aaatgacttg gaaaattgta acagattcag gatgtgatct
    65101 tagaagtttg actagacaat ccaaagagtt gcgctttgaa cgtgtgcctt tgaccctaca
    65161 gattggcaca gaaattttta gagatgatga tggattagat atcgataata tgatgacaac
    65221 tatgtaccag tcgtctaaag caacgacatc cagctgtcca agcccagaag cctttttgca
    65281 ggcctataga ggtgcagata atgttatcgt gatgacaatt acagggacct tatctggcag
    65341 tcataatagt gcacgactgg ctaaaaatga acttcttgaa gaaaatccta atgtcaatat
    65401 tcacctaatc gattctttat cagcaggtgg cgagatggat ttgctcgtac tggagcttga
    65461 gcggttgatc aatcttggat tatcctttga agaagttgtc aaacagatca cagcttatca
    65521 gcaaaaaaca cgtttgattt ttgtgcttgc caaggttgat aatttggtta aaaatggtcg
    65581 actgagtaaa ttagtaggta aagtaattgg cttactcaat attagaatgg ttgggaaagc
    65641 tagcaataaa ggaacgcttg aacttcttca aaaagcgcgt ggtcaaaaaa aagcagtttc
    65701 tgctttgata gaagaaattc aaaaagaggg ttatgtaggc ggaaaagttt acattgctca
    65761 tgctcaaaat ccaaaaattt gtgagcagat cagtgaaaaa atcaaatctt tatatcctga
    65821 tgctgtgatt caaactggaa ggacctcagg tttgtgtagc ttttatgctg aagacggagg
    65881 acttttaatg ggctacgaaa tttaatgcta tctaacaaaa caaaaagcta gactcttttg
    65941 atttgagcta gcttttttaa gatgtcagga agactaatca ctaagatagc cgtctaaaac
    66001 gtttattgat tgattttacg aaaaactttt gtattactct tttgatgatt gcttgtctcc
    66061 tgagtcggaa ggttctgaag aggtctgagg cggaattgga tcaggatgac taggttgtgg
    66121 cgtaacatct gaagctgaag attctgagct tgggtctaaa gtaggtgact gggaattatc
    66181 ataagtatct gagacgtctc ctgggaaagg tgtccagtaa gagttatctg ttatttctcc
    66241 actttgtctt ggaaattcat caataatggg tttcgctggt aaaatagcgt ctaaccgaga
    66301 ttgtaaagcg gcttttttac ctttgttact taagtcgtta actgcttttt gggcgatatc
    66361 tttaagattt tgattgagag tctcctcagc agctttaact gcttgagtag ctgcatcttc
    66421 ttgctcttgc tttgctttgg caacgtttag ctgttcttgt agcgtttttt tcttagaaga
    66481 ttctgctaat ttatcaacag ctttctgggc ttcttggata gcagctgcag tggctaaacg
    66541 atcagcgtca ttaactgctt taactgcttt ttttagtaaa ctagcagcac ttttagaatg
    66601 tttagctacc ttatcttgcg tttgagggtg ggatccaaaa ataaggcagg agccacctat
    66661 tagagtgata gttagaacac tcaacatcca ataaagcgcc tctttttgtg atttagtcat
    66721 ggaatctcct ttatgatatt gtttcatcgt agccatatta tacctctaat taaacgaaat
    66781 gaaaagattt gtgcaaaaac aaatgatgta aaatatcgga aaagcctaac accttatcaa
    66841 accaataata tgcaaatgtt gacatcggta tacacagaaa cgcttaaaaa aaccttgtga
    66901 taaagaccgt aatacattaa aatagaatag actaaaaaaa tgagcgagga caatattgtg
    66961 tcagtaaatt ggcaagacat tgcatttcat ttctttggag gcttaggtct ctttcttttc
    67021 agtatcaagt atatgggaga tggtctgcaa caagcagcag gagataaact aaggtattac
    67081 attgataaat ataccagtaa tccctttttt ggtatcttag tcggaattgc catgtctgcc
    67141 ttaattcagt ccagttcagg cgtcactgtg attacggttg gtttggtttc tgcgggtttg
    67201 ctaaatttgc gacaagccat tggaattgtt atgggggcta atattggaac gactatcact
    67261 tcgtttttaa ttggttttaa actaggagat tacgccttgc ccatgatttt tattggtgca
    67321 gcctgtcttt tctttacctc taataaaaag ctcaacaatt ttgggcgtat catttttggt
    67381 gtcggaggaa ttttcttctc gctgaaccta atgggagatg ccatggatcc tttgaaatct
    67441 gtgtcagcct ttcaaaatta tttagcgaca ttaggtgata aacccttcca aggtgtcttt
    67501 atcggaacgg ctttgaccat gttgattcag tcatcggcag ccattatcgg gattttacag
    67561 ggtctgtttt caggcggtct tttgacctta cagggggcta ttcctatttt gttaggctca
    67621 aatataggaa cctgcattac agctgtctta gcagctatag gttcaaatat tgctgctaaa
    67681 cgtgtggcag cagctcatgt gttatttaat ttgatcggta caattatttt tatgattatc
    67741 ctagtcccat tcacatcatt gatgttatgg ctacaatcaa agttgagttt aacgcctgag
    67801 atgactatcg ctttttctca cggttctttt aatatcacta ataccatctt attaattcct
    67861 ttcattagtc tactagctat gattgtgact agactcattc caggagaaga tgaagtggtc
    67921 aaatacgaag ccctttattt agatcgctta cttattaccc aagccccttc tatcgcacta
    67981 ggaaatgccc acaaggaatt ggttcattta gcctcttatg cgattcaagc ttttgaagct
    68041 tcttacagtt atattatgac agctgacggt aaatttgggg aaaaggtcaa gcgttatgaa
    68101 agagcagttg ataccatcga tgaggagtta accacttatt tggttgatat ttctaacgaa
    68161 gccctcagcc caagtgaaaa tgaagtcttg gctggtattc ttgactcttc acgtgatttg
    68221 gaaagaattg gagatcattc tgagtcttta ggcattctaa ttgaaggcat catatctaaa
    68281 caaattggtt tttcaatatc tgctcgtcaa gaattgacag agatgtatca attgacgcat
    68341 tgtttaacac tggatgccat tagagctatc gttgatagtg atacagactt ggcgcaaact
    68401 attgtgactc gccataaaga aattgaagaa aaagagcgac gattacgtaa aacccacatt
    68461 aagcgcttga attgtggaga atgtacggca caagcaggta ttaattttat tgatattatt
    68521 tcccactata cccgcatcac agatcacgcc ttgaatttag cagagaaagt actttcacac
    68581 cagctttaaa aaaagagaaa acgtgaatga tcatccacgt tttctttttt gaatccaaaa
    68641 agtggtatat accatttaca aagtaaagaa taaggcgtat aataaggaaa aaagggagga
    68701 aaaaagatga catgctatct taaagcagat tgtttttatt acccaacaga ggtgaaaccg
    68761 gctggctacc taggtcttca tgatggtgtt tttggggagt ggatagaaat tgttccggca
    68821 gatgcgcaaa tcattgacta caccggttat caaattgcac caggtcttgt ggatacgcat
    68881 atccatggct atgcgggagc tgatgtcatg gataattctg cccaagggat tcatcaaatg
    68941 agtgaaggac tattagcaac aggagtaacg tcttttttac cgacgacctt aacttctacc
    69001 tttgagcagt tagaaaaagt atcagggact attgcttcag ttgctgatca ggtaaaaggt
    69061 gctaaaatac aaggtattta ctttgaaggt ccttatttta ccgaagaata taagggtgct
    69121 caaaacccaa gttatatgaa aaacccacgc ttggaggaat ttgatgcttg gcaaaaagcc
    69181 gctaaagggc tcatcaaaaa aattgccctt gctcctgagc gtgatggtgt caaagaattt
    69241 gtgtccgcag tgacaaaaca aggcgtaaca gtggccttag ggcattcaaa cggtacttat
    69301 caagaggcta aagaagctgt tcaagctggt gctagtgttt gggttcatgc ttataatggc
    69361 atgcgaggat tgacccaccg tgaaccaggg atggtgggag cggtttataa tcttccaaat
    69421 acttacgcag agttgatttg tgatggccac catgtctcac caattgcttg tgatattttg
    69481 atgcagcaaa aagggcatga tcatgtagcc atgattacgg actgtatgcg agcaggtggt
    69541 tcaccagatg gtgattacct cttgggggaa ttctctgtgg ttgtggcaaa tggcactgct
    69601 cgtcttaaag agagtggaaa cttggcagga tctattttga aattaaaaga cggccttaga
    69661 aatgtagtgg cctggggaat cgcaactccg gcagaagcca ttcatatggc aacctatgtg
    69721 ccagctgttt ctgtcggtat tgacgacgta tgtggtcaaa tcaaagctgg gcatgcggct
    69781 gactttattg ttcttgataa ggatttaaca cttgttgcaa cctatttaaa tgggcaaaaa
    69841 gcttttgatg cctaagagat acaaaaggat tggggtagct atgtctggca ggccaattct
    69901 ttttgtattt tctttcttta tgatagaata gattacagta atcgcttaca gagattgata
    69961 aaaggaggtt tttgtgatgg taacaacagt aaaaatgaca agtggctatg agattcccgt
    70021 tttaggattt ggaacttacc aagcagccga tggtgaggaa gcttaccaat ctaccttagc
    70081 agccatcaag gctggctatc gtcatattga tactgcagct atttataaaa atgaagaaag
    70141 tgtgggtcgt gccatcaagg attctggggt tctacgagaa gacttattta ttacaactaa
    70201 actctggaat gacgcccata gttatgaagg ggcaaaagac gctttagctg cttctcttga
    70261 ccatcttggt ctggattatg tggatctcta tcttatccat tggccaaacc caaaagctct
    70321 gcgtaacact tggaaagagg caaatgctca agcatggcaa tatatggaag aggcggttga
    70381 agcaggactc attaaaagca ttggcgtcag caattttatg gtgcatcatc tagaagctct
    70441 tcaagagaca gctaaaataa ctccagcaat taatcagatt cgattagccc caggttgcta
    70501 tcaaaaggaa gtggttgatt attgtaaggc aaatgagatt ttattggaag cttggagtcc
    70561 tctaggacaa ggggagattt ttgataatga gactatgcag cagttagcta ataaatatga
    70621 caaaacagtg gcacaagttg ccttagcttg gtcgctggca gaaggtttta ttcccttgcc
    70681 aaaatcggtg catgatgagc gcatcaagga aaatatggct atttttgatg tgagcttgac
    70741 acaagaagat aaaaaaacaa ttcgctatct ctcaggaatg tcagcgactc ctaaccctga
    70801 tactacaagt ttttaggaaa gtacaaagat ttagccataa ttcgctaaat cttttttgaa
    70861 aacggtttga caaaggttta tcatttagct ataatcttta ttagtgtttt gtgaaagaaa
    70921 ctattattga aaataaggag ccgtattgtg accatctttt tagtgatgtt agccatgttt
    70981 actattcgtt tagtattttt gaagaaatcg ataacaaatg aaaaagccat attagcccaa
    71041 ggaggacagg aatttggtgc tcagaacacg aaatttttga cgttacttca cattatgatt
    71101 tatgtgtttg cggtgattga agcgctgctt aaacaaatta agtttgatgg catcagtttt
    71161 ttaggtcttt tgttgatgtt attatcagta gctgttttat atgaagtgac acgtatctta
    71221 ggtgacattt ggactgtaaa attgatgtta gcaaaagacc acaaatatgt ggatcactgg
    71281 ttgttcaaaa cgattaaaca tcctaactac tttttaaata tcgcccctga gctggtgggc
    71341 atagccttac tttgccatgc taaaattacg gctatgcttc ttttcccatg ctacattgta
    71401 gtaatatatt tacgtattcg agaagaaaac aagctattag cggaagtgat tattccaaat
    71461 ggtactcgaa caaaacctta agctcatgat ggacaaacta atggctttat gctaaactag
    71521 actctaggaa aaaggatgca agtatcttat ctaaagcgag ttcggggtag ttagagccga
    71581 atggtaggac tgcagattgg cgcttccgtt tgggcagtgt gattaagtat atttgtcaat
    71641 attgcccaaa aagatactat ataaatgaag taataaatta gggtggaacc gcgttttgac
    71701 gcccctaggt cttatgattt aggagcatca aaatgcggtt ttttggtgcc tagacctgta
    71761 atacatgcta gtaacatcgt caggtatttt actgatgaca aaaaaacgat tgtcaatgat
    71821 ataccatttt actactatca aaggagtacg aaatgtctaa aaaacttacc tttcaagaaa
    71881 tcatcttgac cttacaacaa tattggaatg atcagggttg tatgctcatg caagcctatg
    71941 acaatgaaaa aggagctggg accatgagtc cttacacgtt cttacgtgct ataggtcctg
    72001 agccatggaa tgcggcttat gtagagccat cacgtcgtcc tgcagatggc cgttacggag
    72061 aaaacccaaa tcgtctttac caacaccacc aatttcaagt ggtcatgaaa ccatcaccat
    72121 caaatattca agaactttac cttgcttctt tggaaaaatt gggcatcaat cctttagaac
    72181 atgatattcg ttttgttgaa gataactggg aaaacccatc aacaggatca gcagggcttg
    72241 gttgggaagt ttggcttgat ggaatggaaa tcacacaatt tacgtatttc caacaagttg
    72301 gtggccttgc gacatctcca gtgacagcag aagtaactta tggtcttgag cgcttagctt
    72361 cctatattca agaagtggat tcggtctatg atattgagtg ggcaccaggt gttaaatatg
    72421 gtgaaatctt cttacaacct gagtatgagc attcaaaata ttccttcgaa atatcagacc
    72481 aagacatgct gcttgaaaac tttgaaaagt ttgaaaaaga agcctcgcgt gccctagaag
    72541 aaggtttggt tcacccagct tatgattacg tgctcaaatg ttctcatacg tttaacctgc
    72601 tggatgcccg tggcgctgtt tccgtcacag aacgtgcagg ctacattgct cgtatccgta
    72661 atttggcacg tgtcgttgct aagacctttg ttgcagaacg caagaagctt ggatttccac
    72721 tgttggatga agcaacacgc gcaatcttgc tagctgaaga tgacgaataa gtcgatttaa
    72781 agatgatcta gttgcgagct ttgtaatctt aagagcgagc aagaagtggg cgaccgaagg
    72841 tcgccgaatc aaggttactc ccgctgtagt gacaattcgg taaggttact tatcgaacga
    72901 gggagttggc gagactttag gctggctaac taggaatgga acacttttgt tttctgaaat
    72961 tatccactgg ataatttcac tttgcgtccc ccctacctaa gggaacaatc aaaaagatac
    73021 tttttagaga aaggaactga acacgggcta cggactatgt caaaaagacc aagacttcct
    73081 aggtgcaagc acctgcgtcg ctttgctatt ttgatggtgt ccgcttaacg cctttggtat
    73141 cttaattatg agtaaaaatc tactaatcga acttggtctg gaagaacttc cagcctacgt
    73201 ggtcacacca agtgaaaaac aactgggaga gcgcttggcg actttcttaa cagaaaatcg
    73261 tctctctttt gaagatatac aaaccttttc aactccacgc cgtttggcag tgcgtgtgtc
    73321 tggattagct gatcagcaaa cggatttgac tgaggacttt aaagggcctg ctaagaaaat
    73381 tgcccttgat gctgatggga atttctcaaa agctgctcaa ggatttgttc gtggcaaagg
    73441 cttgaccaca gatgctatcg aattccgcga agtcaaagga gaagaatacg tttatgtgac
    73501 caaacacgaa gctggaaaac ctgctaagga agtgcttcta ggcgttactg aagtgttgtc
    73561 agcaatgacc ttcccagtca gcatgcactg ggctaacaat agttttgaat acattcgtcc
    73621 tgctcacacc ttgactgtac tcttggatga tgaagctctg gaccttgact tcttggatat
    73681 tcattctgga cgcgttagcc gtggccaccg tttccttgga aaagagacga ccatcaccag
    73741 tgcagactct tatgaggatg atttgcgcag ccagtttgtt atcgctgatg ctaaagagcg
    73801 tcaagagatg attgtggagc aaatcaagac gctggaagtg gagcagggtg tgcaagttga
    73861 cattgacgaa gacttgctta atgaagtttt gaacttggtc gagtttccaa cagctttcat
    73921 gggaaatttt gaggctaaat accttgatgt cccagaagaa gtattggtaa catcaatgaa
    73981 aaaccaccaa cgttattttg tggtacgtga tcaggctggt cacttgatgc caaactttgt
    74041 atcagttcgt aacgggaatg atcaagccat tgaaaatgtt attaaaggga acgaaaaagt
    74101 tttggtagct cgcttagaag atggtgaatt cttctggcgt gaggatcaga aattgcaaat
    74161 tgctgattta gttgccaaat tgaccaatgt gaccttccat gaaaaaatcg gctctcttgc
    74221 tgaacacatg gatcgtacgc gtgtcattgc cgcatcactt gctaaggaag ccaacctatc
    74281 tgctgaggaa gtcacagctg ttgaccgtgc tgcccaaatt tacaaatttg accttttaac
    74341 aggtatggtt ggtgaatttg atgagctgca agggattatg ggtgaaaaat atgcccgtct
    74401 agctggtgaa gatgctgctg tggcaagggc tatccgagaa cactacttac ctgatgctgc
    74461 aggaggtgcg ctacctgaaa ccaaagttgg cgctgttctg gccttggcag ataaattgga
    74521 tactctcttg tcattctttt ctgttggctt gattccatct ggctctaatg atccttatgc
    74581 tctacgtcgt gcaacgcagg gtatcgttcg tattcttgat cattttggat ggcgcatccc
    74641 aatggataag ctggtagata gcttatatga cttgtccttt gatagtttga cctatgccaa
    74701 caaggcggat gtgatgaact ttatccgtgc tcgtgtggat aagatgatgg gcaaagccgc
    74761 accaaaagac attcgggaag ctattctagc aagctcaacc tttgtggttc cagaaatgtt
    74821 agcggtagct gaagctcttg tcaaagccag ccatacggaa aattacaaac cagcagttga
    74881 atctttgtca cgtgctttta atttggcaga aaaagcggac gcttctgttc aggtggaccc
    74941 tagcctcttt gaaaatgagc aagaaaacac tttgtttgca gttattcaag gcttgactct
    75001 agcaggcagt gctgcccagc agttagaaca ggtctttgct cttagcccag tgattaatga
    75061 tttctttgat aacacaatgg ttatggcaga agatcaagcc cttaagaaca accgtttagc
    75121 tattttatca gatttagtaa gcaaagctaa gaccattgct gcttttaacc aactaaacac
    75181 caagtaaata gaaaggaaag agccgttggg gacttagcta gaaaagtgag ttcagtaccc
    75241 gagtggaaaa aacaaggcct ttaaacattg cttttcacag tgagagttaa gtcagttttt
    75301 taagccttat acttttttcc caggctctta gtggcttaac atggatccta aaaaaattgc
    75361 tcgtatcaat gagctggcta aaaagaaaaa aacggtaggc ttgactggac ctgaaaaagt
    75421 ggaacaggca aaactccgtg aagaatacat tgaaggctat cgtcgctctg tcagacacca
    75481 tatcgaaggc atcaaattgg tggacgaaga aggaaacgac gtgacccctg aaaaattaag
    75541 acaggtgcaa cgtgaaaaag gcttgcacgg ccgttcatta gatgacccaa aatcataaga
    75601 caaaaagcag ctctgaactg ctttttgttt atcgtgatga ctgttagctt ttattttaaa
    75661 tggtatgata cttcaaagtg accacacgtt tttatattgt atagtcaaaa tattaggaaa
    75721 aaccatgtgt ttgagttata atagaagaaa tcaaagaaag aaggtagtac ttatgacaat
    75781 taaaaaattc tctctactag ccatagccag cctctcttta ctcagtcttg cagcctgtga
    75841 tatggatgat aaagacgatc atatggataa tcaaccaaag acaagtcaaa ctagcaagaa
    75901 agttaaactt tcagaagaca aagccaaatc aattgcgtta aaagatgctt ctgttacgga
    75961 agctgatgct caaatgctat cagttacaca agataatgaa gatggcaaag ccgtgtatga
    76021 aatcgaattt caaaacaaag atcaagaata cagttatacc attgacgcca actcagggga
    76081 tattgtggaa aaatcttctg aaccaatcaa tgactaatca agaactgtaa tgaataagac
    76141 agccttaact cttgtgccca attgtctttg cctcttaggc acggctgttt gataccgtgt
    76201 tgcctttgag gcttagttct ctttatgacc caatgatgac tctggattag aagagtgatt
    76261 gttgggtctt ttgattttct ttgataagaa agattacctc gttagaaatg aggagacgtg
    76321 gttgtcatca gtggattttt caagatcatc tagtgggata agctacctat cttatcagct
    76381 tttttttagc tttaaaaatt cttgataata tatttctgat aaaattagct ataatagaat
    76441 caaataggaa aacgcttact taaaggaggg taatgaatgt cgcaagaaaa gtatatcatg
    76501 gctattgatc agggaacaac aagttcacga gcgattattt tcaatcaaaa aggggaaaag
    76561 gttagcagta gccaaaaaga attccctcag attttcccac acgctggttg ggtagagcac
    76621 aatgctaatc agatttggaa ttcggttcag tctgttattg cgggtgcttt tattgagtcc
    76681 agcatcaaac caagccaaat tgaagcaatc ggaattacca accaacgtga gaccacagtg
    76741 gtttgggaca aaaaaacggg tgtacctatt tataatgcta ttgtgtggca atcacggcag
    76801 acggcaccaa ttgctgagca actcaaacaa gatggccata caaaaatgat ccatgaaaag
    76861 acaggccttg ttattgatgc ttacttttct gcaaccaaga tccgttggat tttggaccat
    76921 gtgccaggtg ctcaagaacg agctgaaaaa ggcgagttac tttttggaac cattgatact
    76981 tggctggttt ggaaattgac agatggtgct gttcatgtga cggattattc caatgcggct
    77041 cgtaccatgc tctataatat taaagactta acatgggatg atgagatttt agagctttta
    77101 aatattccaa aagatatgct tccagaggtt aaatccaatt ctgaaattta tggcaaaaca
    77161 gctgcctttc atttttatgg gggcgaagtg cctatttcag gtatggcggg tgaccaacag
    77221 gcagctttgt ttggccaact agcttttgag cctggtatgg tgaaaaacac ttatggcacc
    77281 ggttctttca ttatcatgaa tactggtgat gagatgcagt tatcgagtaa taatcttttg
    77341 accaccattg gttacgggat taatgggaag gttcactatg ccttggaagg ttccatcttt
    77401 attgcaggct ctgccattca atggttgcga gatggtctta aaatgattga gacttcacca
    77461 gaatctgaac agttcgctct agcatcaact agtgacgatg aagtttatgt tgtgcctgct
    77521 tttaccggtt taggagctcc ttactgggat tctaatgcgc gtggatctgt ctttggcttg
    77581 acacgtggta ccagcaaaga agactttgtc aaagcaacct tacaatctat cgcctatcaa
    77641 gtgcgagatg ttattgatac catgcaggtg gattcaggta ttgacattca acagctccgt
    77701 gtggatggcg gtgcagccat gaataatatg ctcatgcaat ttcaggctga tattttagga
    77761 attgatattg cccgtgctaa aaatttagaa acaacagctc taggagcagc tttcttagca
    77821 gggcttgctg tgggctactg ggaagacatg gatgctttga aagagttaaa tgccacaggc
    77881 cagctcttta aggctagcat gaatgaatcg cgcaaagaaa aattatacaa gggttggaag
    77941 cgcgctgtta aagcaactca agttttcacc caagaagaag atgcagatga cgatgcaaaa
    78001 taactagagg aggatggaat ggaattttca aaagagacaa gacgcttagc tctccaaaaa
    78061 atgcaagaaa gagatttaga cctactgatt attgggggag gtattacggg tgctggtgtg
    78121 gcgcttcagg cggcagctag tggcctagat acgggtctga ttgagatgca agattttgcg
    78181 gaaggaacct ccagtcggtc gaccaaattg gttcatgggg gacttcgtta cttgaaacag
    78241 tttgacgttg aagtcgtctc agatactgtt tcagaacgtg ctgtggtcca acagattgca
    78301 cctcatattc ctaagccaga tcctatgtta ttacctgttt atgacgaacc tggcagcacc
    78361 tttagcatgt tccgtttgaa ggtcgctatg gatttgtatg atcttttagc aggcgtgtcc
    78421 aatacgccag cggccaacaa ggtgttaacc aaagaagaag tcttaaaacg agaaccagac
    78481 ttaaaacaag aaggcctgct tggtggtggc gtttaccttg atttccgcaa taatgatgca
    78541 aggcttgtta ttgaaaatat caaacgagct aatcgtgatg gggctcttat tgctagtcat
    78601 gtgaaagcag aagatttctt gctagatgac aatggtaaga ttattggtgt gaaggcgcgt
    78661 gatttgctgt cagatcaaga aatcattatc aaggctaaat tagtcatcaa caccacaggt
    78721 ccatggagtg atgagattcg tcaattctct cataagggac aaccgattca tcaaatgcgc
    78781 cctacaaaag gggtgcatct ggtagtggac cgtcaaaaat taccagtgtc tcaacctgtc
    78841 tatgttgaca cagggttaaa tgatggtcgt atggtctttg tcttgccacg tgaagaaaaa
    78901 acttattttg gaacaacgga cacggactac actggagact tggagcaccc acaagttact
    78961 caagaagatg tggattattt gttaggcgtt gtcaataacc gctttccaaa tgccaacgtg
    79021 accattgatg atattgaaag cagttgggct ggtcttcgcc ccttgttatc aggtaatagt
    79081 gcttctgact acaatggtgg caacagcggt aaagtcagtg atgatagttt tgatcacttg
    79141 gttgatactg tcaaagccta tattaaccac gaagatagcc gagaagctgt tgaaaaagct
    79201 attaagcagg ttgaaaccag cacatctgaa aaagaattgg atccgtctgc agtgtcacga
    79261 ggttcaagtt ttgaccgtga tgagaatgga ctctttacct tggcaggtgg taagattacc
    79321 gactatcgca aaatggctga aggagcattg acagggatta ttcaaatcct caaagaagag
    79381 tttggcaaat ccttcaagct tatcaattca aaaacctatc ctgtttcagg aggtgaaatc
    79441 aatccagcca atgtagattc ggaaatagaa gcctatgctc aattaggaac tcttagtggt
    79501 ctttcgatgg atgatgctag gtatttggca aacctttatg gttctaatgc gccaaaagtc
    79561 tttgccttaa ctcgtcaatt aacagcagct gaagggttaa gtttagctga aaccttgtcc
    79621 ttacattatg cgatggatta tgaaatggct cttaaaccga cagattattt cttgagaaga
    79681 acaaatcacc tcttatttat gcgagatagc ctagatgctt tgattgaccc agtgattaat
    79741 gaaatggcta aacattttga atggtctgat caggaaagag tggcacaaga agacgatctt
    79801 cgtcgcgtga ttgcagacaa tgatttgagt gccctaaaag gccatcagga gggttaatat
    79861 ggatatcttt ggtgaatttt tgggtacagt cttattggtt ttactaggaa atggtgtggt
    79921 agcaggggtt gtcttgccca aaacgaaaac ccatgcttct ggctggatcg tgattgcgac
    79981 tggctgggga attgcagttg ctgtggcagt ctttatcagt ggcaaagttg cccctgccta
    80041 cctcaatcca gctgttagcc ttgcttttgc catgagtgga accattgcct ggtcaacagc
    80101 cattgcctat agccttgccc aactattggg agctatggtt ggttcaactc tggtattcct
    80161 tcagttcagg ccacattatc tggctgctga gagtcaggct gatattttag ggacatttgc
    80221 gacaggtcct gctattcgag atactagctc aaacctattg agtgaaatct ttgggacctt
    80281 tgtcttgatg cttggtattt tggcatttgg cttatatgat atgccagcag gactaggaac
    80341 cctctgtgta ggtaccttgg ttattgggat tgggttatcc ttaggaggaa cgacaggtta
    80401 cgccattaac ccagcgcgtg atttaggacc tcgtctagtt catgctattc taccactcaa
    80461 caacaaggga gattctgatt ggtcttatgc ttggatacct gttgtaggac caattattgg
    80521 agcggcctta gcagttttgc ttttccaagt catgtcctaa ccatcactaa aggggttggc
    80581 tatcataggc cagctccttt gcattttctt tataggatta ggtaaaacgc tttcatatct
    80641 taaaaacaac tgctataata atactattat gacattaacg acaaagacca tacatgttat
    80701 cggggcatcc tttgctggtc tagcctttgt tgataaatat aaggacctca atccagattc
    80761 ccaaatcatt ctcattgata aggaaagctg tcccaattat attccaaatg gtatcaacca
    80821 attattcaga ggagacattc aagacctgtc tgatgctatg tggggaagag cctgcctagc
    80881 agcacaaata gaatctaacc accggattat tcaagcagaa gtgttagcta tcgaagctcc
    80941 ctcaaacacc ttgcttctca aagacagtca aggacgagtt tttgaagaag gttatgaaac
    81001 gcttgtttgt gccatgggtg ctagccccca gtctcattat attgagacgt cacagaccaa
    81061 caaagttttg gtaaccaaat attatgaaga aagccaagct agtttaaaac tgattgaggc
    81121 tagccaagag gtcttggtta ttggtgccgg cttgattggc ttagaccttg cctacagttt
    81181 gtcattacaa ggcaaacggg tcaaactgat tgaagcagcc gaacgtccag atttctatca
    81241 gactgacgca gaactgatag cccctgtaat ggcagaaatg tccactcacc atgtcacctt
    81301 tattaataat aagcgtgtta cggctattca tgagatagag ggaaaagttg tcgctcatac
    81361 cgagcaaggg gacaccttcc aaggtgattt ggctatttta gccattaact ttaggccaaa
    81421 tacacacctt ttgcaaggac aagtggcttg tgctctggat aagaccattt tggttaatga
    81481 aaacttacag accagccagg ttaatatcta tgccattgga gacatggttt cattgcattt
    81541 tggtatattg ggaatggatt actatacacc tttgattaac caagcaatga agacaggtca
    81601 ggctctggct ctgcatttag ctggatatcc tattcctcca ttacagacgg tcaaggtatt
    81661 aggaagttct cactttggtt attatcgcgc gagtgttggt gtgacagaag aagaagcaga
    81721 gctttatatg gatacgtgta gctatttgta ccaaaatggg gattctaaaa acctcttttg
    81781 gctgaaatta atagctagaa aaacggatgg gattttaata ggcgctcagc tcctatccaa
    81841 aaccaatgct cttgtcatcg ccaatcaatt aggtcaggct ctggctctga aagttacaga
    81901 cgctgactta gcatttcaag attttctctt tttacaaggt cacagtgatt tggcttatca
    81961 tcttcatgaa gcttgtctca aattatttga aaagaggctc cgccatgaag attgaagact
    82021 taatggataa ggaacgaagg gcccaatatc gtctcttggt gaccctttat catgctaaag
    82081 aaacgttaag gctaaaagac ctaatgaggc tatcaaactt gtctaaagtg accctattaa
    82141 aatacattga caatctaaat catttgtgtc gagaacaagg tttagcctgt caattacttt
    82201 tagaaaaaga cagtctgagc ttaaaagaaa atggccagtt ccattgggag gatttggtag
    82261 ctctgcttct caaagaatcg gttgcctatc agatattgac ctacatgtac tgccataaac
    82321 actttaacat caccaactta tccgttgaac tgatggttag tgaagctact ctaaacagac
    82381 aattagctca cctcaaccag cttttatcag aatttgatct ggcgctctcg caaggcagac
    82441 aactgggaag tgagcttcag tggcgttatt tctattttga attgttccgc cataccttga
    82501 ccagacaagg catagacgcc ttggtcaatc agttagacgc ttcgcatttg gctaccttaa
    82561 ttgagcggct gattggccag tcattatcgg cagaagcctt agaacaatta ttgatttggt
    82621 tggcgatttc gcaagcgcga atgtcctttc aaaaaggcta caatgatcat tttttaagag
    82681 atagtgactt tatgacatct aatattttct ttaagcgctt agaaagcatg cttttacatt
    82741 acttaagacg ctatgccctt gaatttgatg cttttgaagc taagagcctc tttgtctttt
    82801 tgcatgctta tcctctactt cctattgcca gcatgaagta tagtttgggt tttggaggtc
    82861 ctattgctga tcacatttca gaagccttat ggcttttaaa gaaggctcat gtgattatcc
    82921 atcagacaaa ggaggaaatc atttatggct tggggatatt tttttccaaa gcttactttt
    82981 ttaaaggagt tatccttagt caaccaacca atagccaata cctttatcaa ttagtaggcg
    83041 aagataaaag agcgctttta agggttatca taaaccattt agtgctgcaa atggatcagg
    83101 aaacggattt cagtcagcag ttgagtgacg acattttagc attgttgatt ttttccattg
    83161 agcgccacca tgagcctctt ttagtagggc ttgccttggg gcaaaataag gtggaagcag
    83221 ccattgcgga attggccatt agacgtcatt tggggcatcg tagggatttt caattaatgc
    83281 cctatgatca tcagaaagtt tatgattgtc tgattaccta tcagactgtc tgtttaccga
    83341 gacaagattt accctattac cggttaaaac agtatagctc cccctatgaa ctcactgctt
    83401 tagaagcttt tctcaaagac cttttccagc aaaaaaatac acgagaagag gaactctcac
    83461 tcagcccagc agctaagtct agttttgcac acaaaactgt gtgatacttg gtcttttcta
    83521 aggactgtta cacttttata ataataaagt aggatagtct aaaggtagat gatttgaaaa
    83581 agcttatcaa atagagctta acaaaatcga aaatttttgg aggtaagaaa tgaaattttt
    83641 cctagataca gctaatgtag ccgctattaa agcgattaat gaacttggcg ttgtagatgg
    83701 tgtcaccacc aatccaacca ttatctcacg tgaaggacgt gattttgaaa cagttatcaa
    83761 agaaatctgt gacatcgtcg atggcccaat cagtgctgaa gtgacagggt taacagcaga
    83821 tgctatggta gaagaagcta gaagcattgc taagtggcat gacaatgtcg tcgttaaaat
    83881 tccaatgact acagaagggt taaaagcaac aaacattctt tcaaaagaag ggattaaaac
    83941 taatgtgacc ttgattttca cagtaagcca aggtttaatg gcaatgaaag caggcgcaac
    84001 ttacattagc ccatttatcg gtcgtttgga agatattggc acagatgctt atcaattaat
    84061 cagcgacctt cgtgaaatca ttgacttgta cgatttccaa gcagaaatca tcgcagcaag
    84121 tattcgtaca acagcccatg tggaagctgt tgctaaatta ggcgcacaca ttgcgaccat
    84181 tccagatccc ttgtttgcta agatgatgca acatccctta acgacaaatg gtttgaaaac
    84241 ctttatggaa gattgggctt cctttaaaaa ataaggctaa agagtctgtg gctactgtgt
    84301 caacaggctc tcttatattc atcgtcaaaa agaattcacc aatgatgtcc aaactagttt
    84361 ttttctggca aaatagggaa aaagaattta gggactttgg aggattttct gaaaaaagcg
    84421 tctatttttg tgatacaata gacaatagaa aacgtttaat tttagttgta ataaacagag
    84481 aggttttact tatgacattt gatgcaattg accaattggc agtaaacact gtccgcaccc
    84541 tatcaatgga tgccattcaa gcggcaaatt ctggacaccc aggacttcca atgggggcag
    84601 cacctatggc ctatgttctt tggaatcact tcatgaacat caatcccaaa acaagccgta
    84661 attggtcaaa cagagaccgt tttatcctat cagcaggtca tggaagtgcc atgctttata
    84721 gcttgttgca tttagcaggt tatgatttat ctgtagaaga tttaaagaac ttccgtcaat
    84781 ggggttctaa aacaccaggt cacccagaag tgaaccacac agacggtgtc gaagcaacca
    84841 caggacctct tggtcaaggg atcgcaaatg ccgttggtat ggccatggca gaagctcacc
    84901 tagcagctaa atttaacaaa ccaggctttg acatcgttga tcactacaca tttgctttga
    84961 atggtgacgg tgaccttatg gaaggggtca gccaagaagc agcaagtatg gcaggacatt
    85021 taaaacttgg gaaattggtc ttgctatatg attcaaacga catctctctt gatggtccaa
    85081 cctctatggc tttcacagaa gatgtgaaag gacgtttcga agcttacggt tggcaacata
    85141 tccttgtgaa agatggaaat gatttagaag aaattgcagc tgctattgaa gcagctaaag
    85201 ctgaaactga gaaaccaacc atcatcgaag tcaaaaccat tattggtttt ggtgccgaaa
    85261 aacaaggaac ttcagctgtt cacggcgctc ctcttggagc agaaggcatt gcttttgcca
    85321 aaaaagctta ccaatggact catcaagatt ttgaagtgcc tgctgaagta acagagcgct
    85381 ttgctcaagg tcttcaagcg cgtggtgaaa aagcagaaca agcctggaat gacttgtttg
    85441 cagcttatga agcagaatat ccagaattag cagcagaata ccaaaaagcc tttactaacg
    85501 aagctgctca agtagaactt gaagcgcacg aacttggtag ttcaatggcg agtcgtgtat
    85561 ccagtcagca agctatccaa caaatttcag aacaagtagc ctctttctgg ggtgggtcag
    85621 cagacctttc agcttcaaac aatactatgg ttaaggctga aacagatttc caaccaggtc
    85681 actacgaagg ccgtaacatc tggtttggcg ttcgtgaatt tgccatggct gcagccatga
    85741 acggtattgc ccttcacggc gggacacgcg tttacggcgg aaccttcttt gtcttctcaa
    85801 actatcttct tccagctgtt cgtatggcag cgctccaaaa cttgccaaca gtttatgtca
    85861 tgacacatga ttctatcgct gtcggtgaag atgggccaac gcacgaacca attgaacaat
    85921 tggcaagtgt tcgctcaatg cctaacttga acgttattcg tccagcagac ggtaacgaaa
    85981 caaatgctgc ttggaaacgt gccattgctg aaacagatcg cccaaccatg cttgtattga
    86041 cgcgtcaaaa ccttccagtg cttgagggca caaaagaatt ggcagaagat ggtcttaaca
    86101 aaggagctta tatcttgtca gaagccaaag gcgaccttga tggtatcatc attgcaacag
    86161 gttcagaagt gaaactggca atggatactc aagaagctct tgaagcagaa gacattcatg
    86221 tgcgtgtcgt atctatgcca tcacaaaata tctttgacga acagtcagca gagtataaag
    86281 aaagcatcct accagcagct gtgactaaac gtctcgctat cgaagcaggt tcaagctttg
    86341 gctgggcaaa atatgtcggc ctagcaggaa aaacattgac cattgacact tggggtgctt
    86401 cagctccagg aaatcgtatc ttcgaagaat atggtttcac tgtggcaaat gcaactgagt
    86461 tatacaaatc actctaggtt acacatccca aacagagtaa atcatttgat ttactctgtt
    86521 tttttaaaat aaaatactca gttctttctt ttcctcaaac tgcctaatac acttcttttg
    86581 ataagaagtc attgacaaaa cgattcataa a
//
LOCUS       DAUGOH010000003        82672 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUGOH010000003 DAUGOH010000000
VERSION     DAUGOH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82672
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.003"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            122..1336
                     /gene="sstT"
                     /locus_tag="VH957_000165"
     CDS             122..1336
                     /gene="sstT"
                     /locus_tag="VH957_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEQ8558115.1"
                     /translation="MKKIYNLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIFLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVVEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(1391..2065)
                     /locus_tag="VH957_000166"
     CDS             complement(1391..2065)
                     /locus_tag="VH957_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEQ8558116.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(2075..3466)
                     /locus_tag="VH957_000167"
     CDS             complement(2075..3466)
                     /locus_tag="VH957_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEQ8558117.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSIEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(3536..4249)
                     /gene="rsmG"
                     /locus_tag="VH957_000168"
     CDS             complement(3536..4249)
                     /gene="rsmG"
                     /locus_tag="VH957_000168"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEQ8558118.1"
                     /translation="MTPQDFYRTLEKDGFLLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEKNEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            4399..4956
                     /locus_tag="VH957_000169"
     CDS             4399..4956
                     /locus_tag="VH957_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEQ8558119.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            5003..5899
                     /gene="htpX"
                     /locus_tag="VH957_000170"
     CDS             5003..5899
                     /gene="htpX"
                     /locus_tag="VH957_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEQ8558120.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            6133..6666
                     /locus_tag="VH957_000171"
     CDS             6133..6666
                     /locus_tag="VH957_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEQ8558121.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPICLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            6933..7619
                     /gene="covR"
                     /locus_tag="VH957_000172"
                     /gene_synonym="csrR"
     CDS             6933..7619
                     /gene="covR"
                     /locus_tag="VH957_000172"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEQ8558122.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            7625..9127
                     /gene="covS"
                     /locus_tag="VH957_000173"
                     /gene_synonym="csrS"
     CDS             7625..9127
                     /gene="covS"
                     /locus_tag="VH957_000173"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEQ8558123.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            9342..9836
                     /gene="nrdR"
                     /locus_tag="VH957_000174"
     CDS             9342..9836
                     /gene="nrdR"
                     /locus_tag="VH957_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEQ8558124.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVIQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            9820..10995
                     /locus_tag="VH957_000175"
     CDS             9820..10995
                     /locus_tag="VH957_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEQ8558125.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAASIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGNLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            10996..11898
                     /gene="dnaI"
                     /locus_tag="VH957_000176"
     CDS             10996..11898
                     /gene="dnaI"
                     /locus_tag="VH957_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEQ8558126.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            11961..13271
                     /gene="der"
                     /locus_tag="VH957_000177"
     CDS             11961..13271
                     /gene="der"
                     /locus_tag="VH957_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEQ8558127.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVISAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            13478..16576
                     /locus_tag="VH957_000178"
     CDS             13478..16576
                     /locus_tag="VH957_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8558128.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASDTDKGDNENIFPNHARHL
                     RLPSGFFEEGVHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGESGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            16820..17422
                     /locus_tag="VH957_000179"
     CDS             16820..17422
                     /locus_tag="VH957_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558129.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            17462..18790
                     /locus_tag="VH957_000180"
     CDS             17462..18790
                     /locus_tag="VH957_000180"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEQ8558130.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEKGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            18836..19318
                     /locus_tag="VH957_000181"
     CDS             18836..19318
                     /locus_tag="VH957_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8558131.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            19430..21004
                     /gene="mltG"
                     /locus_tag="VH957_000182"
     CDS             19430..21004
                     /gene="mltG"
                     /locus_tag="VH957_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEQ8558132.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKDAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAFTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            21077..21559
                     /gene="greA"
                     /locus_tag="VH957_000183"
     CDS             21077..21559
                     /gene="greA"
                     /locus_tag="VH957_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEQ8558133.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(22183..23106)
                     /gene="yidC"
                     /locus_tag="VH957_000184"
     CDS             complement(22183..23106)
                     /gene="yidC"
                     /locus_tag="VH957_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8558134.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMTFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMSIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(23188..23466)
                     /locus_tag="VH957_000185"
     CDS             complement(23188..23466)
                     /locus_tag="VH957_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEQ8558135.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGGIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGN"
     gene            23727..24464
                     /locus_tag="VH957_000186"
     CDS             23727..24464
                     /locus_tag="VH957_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEQ8558136.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            24503..25003
                     /locus_tag="VH957_000187"
     CDS             24503..25003
                     /locus_tag="VH957_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8558137.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            25018..25707
                     /locus_tag="VH957_000188"
     CDS             25018..25707
                     /locus_tag="VH957_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEQ8558138.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            25885..26127
                     /locus_tag="VH957_000189"
     CDS             25885..26127
                     /locus_tag="VH957_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEQ8558139.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            26305..27099
                     /gene="racE"
                     /locus_tag="VH957_000190"
     CDS             26305..27099
                     /gene="racE"
                     /locus_tag="VH957_000190"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEQ8558140.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVEHRFFTTANSEIFQEIASIWLKQKINVEHVTL"
     gene            27096..28082
                     /locus_tag="VH957_000191"
     CDS             27096..28082
                     /locus_tag="VH957_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEQ8558141.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQREIKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDTILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            28061..28582
                     /locus_tag="VH957_000192"
     CDS             28061..28582
                     /locus_tag="VH957_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEQ8558142.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYSSLSKEFKR"
     gene            28579..29040
                     /locus_tag="VH957_000193"
     CDS             28579..29040
                     /locus_tag="VH957_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8558143.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            29037..29783
                     /gene="xerD"
                     /locus_tag="VH957_000194"
     CDS             29037..29783
                     /gene="xerD"
                     /locus_tag="VH957_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEQ8558144.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPMTLEKYYKS"
     gene            29783..30487
                     /locus_tag="VH957_000195"
     CDS             29783..30487
                     /locus_tag="VH957_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEQ8558145.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKNNHTV
                     IERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNKVISIFLASLELIKLHVVFV
                     EQLSNFGAIILRKEKK"
     gene            30484..31035
                     /locus_tag="VH957_000196"
     CDS             30484..31035
                     /locus_tag="VH957_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEQ8558146.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            31156..31878
                     /locus_tag="VH957_000197"
     CDS             31156..31878
                     /locus_tag="VH957_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8558147.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            31875..32138
                     /gene="yidD"
                     /locus_tag="VH957_000198"
     CDS             31875..32138
                     /gene="yidD"
                     /locus_tag="VH957_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEQ8558148.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            32316..32864
                     /locus_tag="VH957_000199"
     CDS             32316..32864
                     /locus_tag="VH957_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEQ8558149.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHIYEHDKLK"
     regulatory      32973..33097
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            33176..33739
                     /locus_tag="VH957_000200"
     CDS             33176..33739
                     /locus_tag="VH957_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8558150.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            33741..34394
                     /locus_tag="VH957_000201"
     CDS             33741..34394
                     /locus_tag="VH957_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8558151.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILLIGLSRIYLGVHYPSDILAGFVLGFGILHFIYPFYKQKRFEWRFLLKQD"
     gene            34687..35607
                     /locus_tag="VH957_000202"
     CDS             34687..35607
                     /locus_tag="VH957_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEQ8558152.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            35646..36200
                     /locus_tag="VH957_000203"
     CDS             35646..36200
                     /locus_tag="VH957_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8558153.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            36333..37667
                     /locus_tag="VH957_000204"
     CDS             36333..37667
                     /locus_tag="VH957_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEQ8558154.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQDQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            37745..38536
                     /gene="pflA"
                     /locus_tag="VH957_000205"
     CDS             37745..38536
                     /gene="pflA"
                     /locus_tag="VH957_000205"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEQ8558155.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            38667..39602
                     /locus_tag="VH957_000206"
     CDS             38667..39602
                     /locus_tag="VH957_000206"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEQ8558156.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            39678..40331
                     /locus_tag="VH957_000207"
     CDS             39678..40331
                     /locus_tag="VH957_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEQ8558157.1"
                     /translation="MITIFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRSQLTLANYFYRLKRGEKPSAEQIDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(40376..41413)
                     /locus_tag="VH957_000208"
     CDS             complement(40376..41413)
                     /locus_tag="VH957_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8558158.1"
                     /translation="MLFMVNKKRRPLLKSQRHLLRLYTSLILLLVSLMGLALSLGESH
                     LSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(41374..42426)
                     /locus_tag="VH957_000209"
     CDS             complement(41374..42426)
                     /locus_tag="VH957_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8558159.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKSYHQLRLVLAGVMVSILLSALGQGITNYYHLTNAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYFLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(42416..43348)
                     /locus_tag="VH957_000210"
     CDS             complement(42416..43348)
                     /locus_tag="VH957_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8558160.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(43374..44156)
                     /locus_tag="VH957_000211"
     CDS             complement(43374..44156)
                     /locus_tag="VH957_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558161.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAIQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(44402..45847)
                     /locus_tag="VH957_000212"
     CDS             complement(44402..45847)
                     /locus_tag="VH957_000212"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEQ8558162.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQ
                     VDGKTLFFAKGATFKAEYLKEAIAKGLPLYVSEVDYKLDIPVVLVTDIKKAMSLIAMA
                     FYDNPQDQLKLLGFTGTKGKTTAAYFAYHILKESYKPALLSTMNTTLDGQTFFKSQLT
                     TPESLDLFAMMAECVKNGMTHLIMEVSSQAYLVGRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            45935..47569
                     /locus_tag="VH957_000213"
     CDS             45935..47569
                     /locus_tag="VH957_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEQ8558163.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGVVFSAIMYLGSPLFTSLSGGDAKLIPIMHSLSLAVLVFPVMSVIRGIFQGHNN
                     IKPYAISQIAEQLIRVIWMLLTTFLIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLTAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWSFVNT
                     MSLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLLALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            47737..48366
                     /gene="upp"
                     /locus_tag="VH957_000214"
     CDS             47737..48366
                     /gene="upp"
                     /locus_tag="VH957_000214"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEQ8558164.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEVHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            48590..49180
                     /locus_tag="VH957_000215"
     CDS             48590..49180
                     /locus_tag="VH957_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEQ8558165.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            49675..49950
                     /locus_tag="VH957_000216"
     CDS             49675..49950
                     /locus_tag="VH957_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEQ8558166.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            50199..50834
                     /locus_tag="VH957_000217"
     CDS             50199..50834
                     /locus_tag="VH957_000217"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEQ8558167.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGG
                     VAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLTKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            50852..51727
                     /locus_tag="VH957_000218"
     CDS             50852..51727
                     /locus_tag="VH957_000218"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEQ8558168.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHTNAANSLLKYIEEPQGEAYMFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            51746..51986
                     /locus_tag="VH957_000219"
                     /pseudo
     CDS             51746..51986
                     /locus_tag="VH957_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
     gene            52390..52713
                     /gene="yabA"
                     /locus_tag="VH957_000220"
     CDS             52390..52713
                     /gene="yabA"
                     /locus_tag="VH957_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEQ8558169.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            52718..53581
                     /gene="rsmI"
                     /locus_tag="VH957_000221"
     CDS             52718..53581
                     /gene="rsmI"
                     /locus_tag="VH957_000221"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEQ8558170.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGAISEILSYL
                     EETPLKGECLLIVAGAQVDSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            53608..54000
                     /locus_tag="VH957_000222"
     CDS             53608..54000
                     /locus_tag="VH957_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558171.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(54047..54676)
                     /locus_tag="VH957_000223"
     CDS             complement(54047..54676)
                     /locus_tag="VH957_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEQ8558172.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQSLSQLTGTAIVHGTKII"
     gene            54976..55332
                     /locus_tag="VH957_000224"
     CDS             54976..55332
                     /locus_tag="VH957_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEQ8558173.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGK
                     VLQVGYRKPYQELDLG"
     gene            complement(55406..56233)
                     /gene="xth"
                     /locus_tag="VH957_000225"
     CDS             complement(55406..56233)
                     /gene="xth"
                     /locus_tag="VH957_000225"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEQ8558174.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDTQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYCLASNRIVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            56467..57648
                     /gene="lctO"
                     /locus_tag="VH957_000226"
     CDS             56467..57648
                     /gene="lctO"
                     /locus_tag="VH957_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEQ8558175.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDYLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVNQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            57914..62857
                     /gene="scpC"
                     /locus_tag="VH957_000227"
     CDS             57914..62857
                     /gene="scpC"
                     /locus_tag="VH957_000227"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEQ8558176.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLVGSVFLMMTTTVAADELTTTSEPT
                     ITNHAQQQAQPLTNTELSSAESQSPDTSQVTPETNREKEQSQDLVSKPTTTELADTDA
                     APMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFGDFD
                     EDWENFEFDADAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDETKY
                     ESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIED
                     AVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDP
                     LATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVD
                     FKDIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKHG
                     ALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVS
                     KAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIA
                     GASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNI
                     DGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKDKTLRYDTELLTDHVDPQ
                     KGRFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRF
                     RDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGK
                     HFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNN
                     QDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTL
                     LGTAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDP
                     ETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVADNKTFVERQA
                     DGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKE
                     TLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKG
                     LKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQ
                     YVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVRE
                     EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVED
                     RAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYY
                     NNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATSQ
                     ITAHFDHLLPEGSRVSLKTAQGQLIPLGQSLYVPKAYGKTVQEGTYEVVVSLPKGYRI
                     EGNTKVNALPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSAT
                     AKALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            63641..64348
                     /locus_tag="VH957_000228"
     CDS             63641..64348
                     /locus_tag="VH957_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEQ8558177.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSFIL
                     TGIAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALIPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            64588..66588
                     /gene="metG"
                     /locus_tag="VH957_000229"
     CDS             64588..66588
                     /gene="metG"
                     /locus_tag="VH957_000229"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEQ8558178.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADCLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADLSQLIDAQLADYHKYMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALAAFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKFYPNEQELVGKKLQIVA
                     NLKPRKMMKKYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            67082..68095
                     /gene="nrdF"
                     /locus_tag="VH957_000230"
     CDS             67082..68095
                     /gene="nrdF"
                     /locus_tag="VH957_000230"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8558179.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            68099..68587
                     /gene="nrdI"
                     /locus_tag="VH957_000231"
     CDS             68099..68587
                     /gene="nrdI"
                     /locus_tag="VH957_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8558180.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            68554..70734
                     /gene="nrdE"
                     /locus_tag="VH957_000232"
     CDS             68554..70734
                     /gene="nrdE"
                     /locus_tag="VH957_000232"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8558181.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLVNPAIKK
                     TYISARKFFQFIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVEAGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDKATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTASGASDETTTECQSCMI"
     gene            complement(70940..71692)
                     /locus_tag="VH957_000233"
     CDS             complement(70940..71692)
                     /locus_tag="VH957_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEQ8558182.1"
                     /translation="MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLIYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHTDITSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTVLKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDHKKLHIEACFKGSL"
     gene            72150..72596
                     /locus_tag="VH957_000234"
     CDS             72150..72596
                     /locus_tag="VH957_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558183.1"
                     /translation="MKTKSKRFLKLATLCLALLGTTLLMTRPVKAEVVMTQSLAEGSN
                     SSEKNSEQQDQDKVQQRGDSKEDWDRGYDDGYKKGEESDTREELDRSTFDSFPPGISD
                     QGEYLDGYEGGYEAGWRKGHPVEAFLEMAWHFLTYAFTSLFGNHGS"
     gene            72752..73108
                     /locus_tag="VH957_000235"
     CDS             72752..73108
                     /locus_tag="VH957_000235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558184.1"
                     /translation="MTYPVKATETPLSGYESTEQALPKSNQVTETLHSEGDLQKIAEK
                     SDDGYKLGYQKGYEAGRKEDASENPDENKLESKSLDYISGYYAGYYRGWDETNKPFQT
                     LLEDIYRWLWEIFFKP"
     gene            73631..74089
                     /locus_tag="VH957_000236"
     CDS             73631..74089
                     /locus_tag="VH957_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558185.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLTTQPVKAEEGQNKQQEVSVS
                     SQSGQSEGEDLSEDSDDKYPYAEGHEAGQDFGYKEGLKAGWQEADPKEPKDIPEPEFN
                     PYESEGEDRNDFKEGFRDGYPAGYVEGWRKSHPLWAIVQDVLPWLYNFLR"
     gene            complement(74171..75669)
                     /locus_tag="VH957_000237"
                     /pseudo
     CDS             complement(74171..75669)
                     /locus_tag="VH957_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612207.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(75866..76682)
                     /locus_tag="VH957_000238"
                     /pseudo
     CDS             complement(75866..76682)
                     /locus_tag="VH957_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            77333..77986
                     /locus_tag="VH957_000239"
     CDS             77333..77986
                     /locus_tag="VH957_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558186.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDAIKWELDPETSQNSPIAVNV
                     DNANKLRFTLPTGWSVSFKRKKDHYNPLEVNNKLVSETKNRNTSPRIVDYGKNGNPIL
                     AIYNDNQGSSGLPITVTVDKPNEGDELTLLYRADDGFFGGFTKLKDSKTLKKEKKEKE
                     RQLAEEKQIEEERKHVEQKQLEESMLKQIREEDHKPWHQRLSESIQDQWWNFKGLFQ"
     gene            complement(78278..78415)
                     /locus_tag="VH957_000240"
     CDS             complement(78278..78415)
                     /locus_tag="VH957_000240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558187.1"
                     /translation="MLTYHELKKAVANRYIKGDMISITRKLVSSLILSFLIELYEYQE
                     F"
     gene            79115..79675
                     /locus_tag="VH957_000241"
     CDS             79115..79675
                     /locus_tag="VH957_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558188.1"
                     /translation="MKTKSKRFLNLATLYLALLGTTLLMGRPVNADNADMDGYGSESK
                     VQREQSPYEKGVRDGHDAGYKQGKQDRQQGSPDASPTPPDKLRVPEPESNPYNKDHDK
                     QNNQRYKNGWDIAYRSSYYTGWYSAEGTGHLESDDYPNEEEGEDISDNSPSQGSTGST
                     DDGFSNLIDMVVDITTFLWGLVSNWF"
     gene            79909..80160
                     /locus_tag="VH957_000242"
     CDS             79909..80160
                     /locus_tag="VH957_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558189.1"
                     /translation="MPEKKVLPVLSMVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLVLAAIAVAVVAYAYYDPTVIPY"
     gene            complement(80255..80887)
                     /locus_tag="VH957_000243"
                     /pseudo
     CDS             complement(80255..80887)
                     /locus_tag="VH957_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            81444..>82672
                     /locus_tag="VH957_000244"
     CDS             81444..>82672
                     /locus_tag="VH957_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEQ8558190.1"
                     /translation="MRKYDIQKLLLSGENQSVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDSDKVLDELYSLLNNPNKINRNVINEESVEVTNVKGK
                     EIIIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINAMLRDSAKESFDSTL
                     VQNFSISDLDRETINRYREKFDDINAEHPFSKLDTEQFLLKINALRRDRTDNKIKPTV
                     AGLLIFGTHNAIKEFIPHYNVEYVLKDFTENNRFKDRVIYDGTWGEDNLFNFFHLVIE
                     KLYLTLNDNSNIQENSLNRIGISKLRIAIREAFVNSLIHSDYKSEKGIMVIRYSDRYI
                     FTNGGTLRIDLKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESRLKY
                     PKLRTQLDSVELTLWDTS"
BASE COUNT        26239 a        15132 c        16897 g        24404 t
ORIGIN      
        1 tagaaattga ctgaaaattc ttagcacaaa aaatggttaa gatatgtagc tcattcgatt
       61 tgacgaatag atagaattat attattataa aaaacatgta actttagtaa ggatgtaacg
      121 tatgaaaaaa atatataatt tatgggttag ggttagtcta atcaaaaaaa taggtatcgg
      181 tgttgtaata ggagtcatgt tgggcatttt ggctcctgat cttacaggtt ttagtatttt
      241 aggaaagtta tttgttggtg gtttaaaggc tatcgcacct ttgcttgtat ttgctttggt
      301 ttcccaagcc atctcccatc agaaaaaagg gagacagact aatatgacat taatcatttt
      361 tctgtattta tttggtacct ttgcgtcagc tttagtagca gtactgacag cttatctatt
      421 ccctttgacg ttagtgttaa atacacctgt aaatacagaa ttatcaccac ctcaaggtgt
      481 tgttgaagtt tttcagtcac ttctattaaa attagtggat aatccgatca atgctttagc
      541 tactgccaat tatattggtg tgctatcatg ggcaattatt tttggactag cattaaaggc
      601 tgcaagtcaa gaaacaaagc atcttataaa aacagcggca gaagttactt cacaaatagt
      661 tgtttggatc atcaatctgg cacctattgg gattatgagt ctggtgttca ctacgatttc
      721 tgaaaacggt gttggaatct tatctgatta tgcttttttg atactagttt tagtaggaac
      781 aatggttttt gtcgccttag tggttaatcc acttattgcg gttttgatta cacgacaaaa
      841 tccttatccc cttgtcttga gatgtttacg tgagtcaggt cttacagcat ttttcacacg
      901 aagttctgca gccaatattc cagtcaatat gcaattatgc caaaaaattg gattgagtaa
      961 agatacttat tcagtgtcaa ttccacttgg agcaactatt aatatgggtg gggcagcaat
     1021 taccatcaat gtcctaacgc ttgctgctgt acacactttt ggtattccta ttgattttct
     1081 aacagccctc ttacttagcg ttgttgctgc tgtctctgct tgtggtgctt ctggtgttgc
     1141 tgggggatcg ttgttactta ttcctgtagc atgtagtttg tttggcattt caaatgatct
     1201 tgcgatgcag gtggttggtg ttggttttat tgttggtgtt atccaggatt cttgtgagac
     1261 agccttaaat tcgtcaaccg atgttctttt tacagctatt gctgaaaatg ctttttggaa
     1321 acgtaaaaaa gcatagctag atttaacata gtaaaaaaca tccttggaaa acgccaagga
     1381 tgttttttta ttatttaaga tagccaagat aatcaaattt ttcaaaggtg tggtcattag
     1441 cgatggccac aatgatagta ttcggttcta aaggttcaaa aggtttgaca ttagtatcta
     1501 aggttttaac ttctttttga cgcatgccaa tcacatttaa ctcatattta cgacgaacat
     1561 ctaactctga aagagattgt ccttcccagc ttttaggaat gacaaattca atcatcgaaa
     1621 taccatgttc caaatagatg atgctttcaa tatgtcgtct gagaaggttt gaagctacac
     1681 gttttccaga atcacgttca ggggtgatga ctttagttgc tccgatgcca tatagcactt
     1741 cttcaaaaat tttattttta gccttggcaa taatggttgg aacaccgagt tttttacagt
     1801 gcatgactgc aagaacagaa gattccaagt tattccctga agcgataacg acagtatcac
     1861 aatgttcaat ccctacagct aatagaaatt ctttgtcagt aatatctcca acagcggctt
     1921 tagtgaccaa gtcggccacc tctttaacat gactttctct gatatcaata gcaataacgt
     1981 cttgatcaaa attacttaat tctctggcaa cagtacggcc aaaaatacca aggccaagaa
     2041 cgccgacagt tttacgtttt aacatgtttt ctccttaacc cactagaata tcagtagtgg
     2101 catattgaat ggttttttct tttcgttgaa tcagactgat gaggacagta attgggccaa
     2161 cgcggccgac gaacatcaag acaatgacaa taagacgtcc agcagtagac aattgtggtg
     2221 tcaaatccat agatacccca actgtcgcga tggcagaaat agattcaaat aagagtggta
     2281 taggagcgat atgaggctcc acgctaagta ataaaataaa acctatcata agaactgcaa
     2341 aaaagaagat aagaactgtc atggtctgct taattgtctt atttgcgata attcggttac
     2401 gaaaggtaac ttctgattgc cctgaaagtt ccgctttaaa gagtaagaaa gtaatggcag
     2461 cagtcgtcac tttaatacca ccagctgttc caccaggagc accaccaata accatttgaa
     2521 tcatataaag aatgttagtc ggtgctaggg tatcgttata agagattgtt gcaaagccag
     2581 ctgttctcat agtgactgtt tgaaaaaatg aaaccataag ttgctgatgt aaactaaaat
     2641 tggcaatggt tttgctgtta tctttttcta aaaaccaggt taagaaggtt ccaagaaaaa
     2701 gaataacagc tgtggtttgt agtactagac gagactgatt ggataattta cgaaaagttg
     2761 ccccataaca atgaggtctt tcaaaaaagt attttttaaa agctactcct aaatcaaccc
     2821 aaaccgcaaa accaagtcca ccagagataa tcaagaacgt aatgataaca tttaatgtag
     2881 gatttaacat aaagtctttt aaactagaag atcctaaatt gtcaaaacca gcgttacaaa
     2941 atgccgacac agctaaaaaa atactattga agataccatt tttccacccg aagcggggga
     3001 taaagtcaat catgataact atcgcagcaa aggcttctat actaaaggtt actttataag
     3061 caaaaaaaag gtagtgcttt aaatctttgc tatcacctcg atttaacgct gattggagca
     3121 aggtttgatc gctcaatcgc atttttcgct tgagggcaaa agtactcaca gctattaacg
     3181 tcaccaagcc aagaccacca atctgcatta gtgccatagc aatggtttgt ccgataccgt
     3241 tatacacttc agcgacggga acaacagaaa gtccagtcac acaaaccatg gaaaccacat
     3301 taaagaaatg atcaagatag acggtattag gaccattttg ataatgggta aagggcatgg
     3361 ataacaagag agtcccaatc agaatcacaa tggcaaaact aaatgttaag cgctgtgtga
     3421 ctgaaagaga tttgataaaa gagcgtttca tgtttcctcc agacataata tctcctacta
     3481 taataacaaa aataagttaa aaaagctaag tttcatctta gcctttggta ctattttata
     3541 gaggtttttt gttaggcaag ccagcttttc ttggatactt gttaggtgtt tcctttttct
     3601 tctcaacaat ggtgatgaag cgagaatctc catttggcaa ttggtagcta tggtttttaa
     3661 tgactttacc aaaaagaaga caaagagcat tcttagcttc ttctaactct tggtcagcag
     3721 cttgtgcctt taaggcgatt aattttcctc caatttttaa aaaggggatg gttaattcag
     3781 atagaacctg catccgagca accgctctgg cagtaacgac atcaaattga cctcgaaagg
     3841 ccttgtcctg tccgaaatct tctgctctac catgaaaaaa atggacattt tccaagccca
     3901 attcctgagc aaggagtgtc agaaaagaaa tccgcttatt aagagaatca ataatggtaa
     3961 cctcaaggtt tgggaaaaga attttcatgg gtaggctagg aaaaccagct ccagctccaa
     4021 tgtccaataa tttgattggt tcattagcta aaaagccctg taaaatagga gcgatggaat
     4081 cataaaaatg cttgaggtaa acttcatttt tttctgtaat agctgttaaa ttaattttag
     4141 tgttccattc cactagtaat ttgaagtagg tgtcaaattg ctctttttgc ttcgatgata
     4201 ataaaaaacc atctttctct agtgttcggt aaaagtcttg gggtgtcatt agtgtcctct
     4261 gtttttgata gttgttacca ttttatcata aaatagccta taacaaaatc caataaatca
     4321 tcagaaataa cacctcatta cttgctatta gcctagaaat tgctataatt gagacacaaa
     4381 gattaaagga gacccactat gccaacagtt ttgattatct tagtcgtttt aggagtgctt
     4441 gcgctatggt taatgattag ttacaatagc ctggttaaat ctcggatgca cacaaaagaa
     4501 gcttggagtc agattgatgt gcaattaaag cgtcgtaatg acttgattcc aaatcttatt
     4561 gaaaccgtaa agggatatgc tagctacgag caaaagacat ttgaaaaaat cactgatttg
     4621 cgtgcgcgtg ttgcgaatgc ctcaactcct caagaaacca tggcggcttc taacgaattg
     4681 agtaaacaag tgaccagttt gtttgccgtt gctgaaaatt acccagactt aaaagctaac
     4741 gaaaacttct tgaaattaca agaagagttg accaatacgg aaaataaaat ctcatattct
     4801 cgtcaactct ataattcaac aacgtctaat tacaaccttc aattagaatc tttcccaagc
     4861 aatatcgctg gtaaattatt tggttttaaa ccaagtgaat tcttacaaac accagaagct
     4921 gaaaaagaag ttccaaaagt tgaatttaac ttttaaatat gaaattatca tctagtaggc
     4981 aatcataaga gaaaggagaa ttatgcttta tcaacagatt tcacaaaata agcaacgaac
     5041 agttgtttta ttagttgttt tcttcgctct cttagcactt attggagcgt cagcaggcta
     5101 tctgctgtta gataattatg ccatgggctt ggttcttgct cttgtcattg gggtgattta
     5161 tgctaccagt atgatttttc aatccaccag tcttgtaatg agtatgaaca atgctagaga
     5221 agttacagaa aaagaggctc caggcttctt ccatattgtc gaggatatgg ctatggtggc
     5281 ccagattccg atgccgagag tttttattat tgaagatcct tctttaaatg cttttgcgac
     5341 aggatctagc cctcaaaatg ctgctgttgc agcaacgaca ggtttacttg aagtcatgaa
     5401 tcgtgaagaa cttgaaggtg ttatcggcca tgaaattagc cacatccgaa attatgatat
     5461 ccgtatttcg actattgctg tagctttggc gagtgctgtt accgttattt ctagtatcgg
     5521 tgggcgtatg ctatggtatg gtggcggttc tcgcaggcaa agagatgacg gagatgatga
     5581 tgttttaaga atcattacgt tacttttgtc gttattatct ttgcttttag cgcccctagt
     5641 agcaagtttg attcagttgg ctatttctcg tcaaagagaa tatctagctg atgctagttc
     5701 tgttgaacta acaagaaatc cccaaggtat gattaaggct cttgaaaaat tgcagttatc
     5761 tcagccaatg aagcatcctg ttgatgatgc tagtgcagcc ttgtatatta atgagcctcg
     5821 caaaaaaagg agcttcagtt cattattcag cacccatcct cctattgagg agaggattga
     5881 aaggttaaaa aacatgtgag cgtttggggt ttttgctcaa gcctcacttt tttatgtctt
     5941 tgggcagata atctaaaatg gcaggaatta tcaaaaatat ctgaacaaaa agaaaaaaat
     6001 gagtgaaaca atggttaaaa atagaatgat ttaaatctta aaattaaaaa acgtcagaaa
     6061 ataaatgcaa aactattgac aaatctttta gatagtagta aaaataaatg agagttttat
     6121 taggagaaga tgatgttagc tatttccgaa atcagaaaac acccagacgg tctctcgttt
     6181 gatcgtttat gtgatgtcaa aagtatgtta cttgagcgtg accaacagat tattgacata
     6241 aaggcagtta aagctgtcgg taatgttcgc tatgataagg ggctttatct gttagattat
     6301 caattgagtt acgaagtgat attaccgtct agccgttcta tggttccgat ctgtttaagt
     6361 gaagtccaac acattcaaga attatttata gaggcgacag atttagctga taagaaagag
     6421 ttggttgaag acaatctggt attagtttta gacaaagacg ctattaacct cgaagaaagt
     6481 attgtggata atatcctact tgctattccg ctacaggtct tgacagagga agaaaagaaa
     6541 tcaaaagagt tgccagcagg tcaaaattgg gcagttttga cagaagaaga ctaccagtgt
     6601 ctaaaagaag aaaagcaaaa agaaaataat ccttttgcta gcttgcaagg gttgtttgat
     6661 gaataaaact gaatattaaa gatgtctgta atttttattt gaaaaaacag ctattctttg
     6721 atatactctt tagagaatat ggttacttat ctaaagtaga aggtattttg accatagagg
     6781 gcaaagaagg taatgactat tagatgcttc atattttatt cgctagaaga ctatttgacc
     6841 attagaactg aaatagtcta ggatatgaga tgaatttcat agttttcttt ctgggagaaa
     6901 aagatagatt aagaggataa gggttggtat aaatgacaaa gaaaatttta attattgaag
     6961 atgaaaagaa tctggctaga ttcgtttctc ttgagctgca acatgagggt tacgaagtca
     7021 ttgttgaggt caatggtcgt gaagggttag aaactgcttt ggaaaaagag tttgatttaa
     7081 tcctgcttga cttaatgtta ccagagatgg atggttttga agtgacccgt cgtttgcaaa
     7141 ccgaaaaaac aacgtatatc atgatgatga ctgcgcgtga ttctattatg gatgtggttg
     7201 caggtttaga ccgcggtgca gacgactata ttgttaaacc gtttgccatt gaagaactac
     7261 ttgcccgtat tcgtgctatt ttccgccgtc aagatattga atctgagaag aaagtgccta
     7321 gtcaaggcat ttatcgagat ctagttttaa atccacaaaa ccgttcagtt aatcgtggcg
     7381 acgatgagat ttctctcact aaacgtgaat atgatttgct taatattttg atgactaata
     7441 tgaatcgtgt catgacacgt gaagaattat tgtcaaatgt ttggaaatat gatgaagccg
     7501 ttgagactaa tgttgtagat gtctatattc gttatctccg cggcaaaatt gacattccag
     7561 gcaaggaatc ttatatccaa acagtgcgtg gcatgggata cgttattcgt gagaaataag
     7621 tcatatggaa aatcagaaac aaaaacagaa gaaatataaa aactcgttac caaaacgact
     7681 atctaatatc ttttttgttc tttttttctg cattttctct gcctttacac tgattgccta
     7741 tagttcaaca aactatttct tattgaagaa agaaaagcag tcagtctttc aagctgtaaa
     7801 tattgttaga gttcgtcttt ctgaggtgga ctctaatttt acattagaga acttagcaga
     7861 agttttgtac aaaaacgata aaacacatct gagaattgat gacagaaagg gcagtcgagt
     7921 cattaggagt gagcgcgata tcacaaatac tctagatgcg aatcaagata tttatgtcta
     7981 taacattgat aaacagatga tttttaccac agataacgaa gaatcatctc ctggcttgca
     8041 tggtcctatt ggtcgggtgt atcacgacca tatcgaagat cagtatcgtg ggttttccat
     8101 gacacaaaag gtatattcta atcggactgg aaaatttgtg ggctatgttc aagtctttca
     8161 tgatttaggc aattattatg tcattagagc aagactgctg ttttggctac tagttgttga
     8221 gttatttggc acaagcttag cctatttaat catcttaatt actacgcggc gctttttgaa
     8281 gcctttacac aatttacatg aagtgatgcg taatatctct gaaaatccta ataatttaaa
     8341 cctgcgctca gatatttcgt caggagatga aatcgaagaa ttgtctgtta tctttgacaa
     8401 tatgttagac aaattggaga cacatactaa gttgcaatca cgttttatta gtgatgtcag
     8461 ccatgaatta cgaacaccgg ttgcgattat taaagggcat attggtctct tacaacgttg
     8521 gggtaaagat gacagtgata tacttgaaga aagcttgaca gcaacagcgc atgaggctga
     8581 ccgtatggca atcatgatta atgatatgtt agacatgatt cgcgtacaag gctcatttga
     8641 gggacatcaa aatgatatga cagttttgga agattctatt gaaactgttg ttggtaattt
     8701 tagagtttta agagaagatt ttatctttac atggcagtca gaaaatccaa aaacgatagc
     8761 ccgtatttat aaaaatcatt ttgagcaggc tttgatgatt ctgattgaca atgctgtgaa
     8821 gtattcccgt aaagaaaaga aaatcgcgat taacctttca gtgactggca aacaagaagc
     8881 tattgttaga gttcaagata aaggcgaagg aatttctaaa gaagatattg aacatatctt
     8941 tgaacgcttt tatagaacgg ataaatcacg taatcgaaca agtacccagg ctggattagg
     9001 gattggcttg tctattctca agcaaattgt agatgggtat catttacaga tgaaggttga
     9061 aagtgaatta aatgaaggtt cagtgtttat cttacatatt cctttggccc agtctaaaga
     9121 gagttagagt agcttaaggc attgttaatg tgacaggtat agtatgtaat cattagataa
     9181 tagtagcagt cttttgccac aactggttag aagctgatgc tattttttta gcaatgatgg
     9241 atgacatgaa agaaatactg tcaatcgcga tgccttttgt tatccttgag aatatggtaa
     9301 aatagtgtat tagattaatt tgatagaatt ggggtgtttg cgtgcgttgt ccaaaatgta
     9361 attaccataa atcgagtgtt gttgacagta gacaagctga agacggcaac accattcgtc
     9421 gtcgaagaga atgtgaacag tgtcatactc gctttactac ctttgagcgt gttgaagaac
     9481 tccctttatt agtcatcaaa aaagatggca cacgagagca attttctaga gataaaatat
     9541 taaatggggt tatccaaagt gcgcaaaaac gacctgtctc gagcacagat attgaaaatg
     9601 tcatttctcg tattgaacaa gaagttcgaa caacctacga aaatgaagtg tcaagtactg
     9661 ctattggtaa tttagtgatg gatgagttgg ccgaacttga tgaaatcaca tatgtacgct
     9721 ttgctagtgt ctacaagagc ttcaaggacg ttgatgaaat cgaagaactt ttgcaacaaa
     9781 ttacgaatcg cgtacgcgga aagaaaaaac gtttaaataa tgatgaaacc aattgatact
     9841 tttacatatc taaaacgcaa caaagtaact cttgattcgg tgactttaat acagttgtac
     9901 tttccaatta ttggaagtga cgcagcctct atctatcaat actttattca cttttttgac
     9961 gatggtttac aacgtcataa attcagcgat attttaaatc acctacagtt tggtatgaaa
    10021 cgttttgaag atgctcttgc catattgaca gcaatggaat tagtgagtgt gtatcagcta
    10081 tcagatacat atctcattac gttgcaccag ccgcttagcc gtgacttgtt ttttcaacat
    10141 ccagcttatt ctcgattatt agaacaaaag attggagagg tagctgtctc tgagttgcag
    10201 gtaactgtcc caagtcaagc aagaaatatt tctaagcgat tttcggatat ttttggggtg
    10261 caaggaaatt tgacgaacgt acctcaaaag ccacaaaaga attttgacct ttcaagtttc
    10321 cagcaattaa tggttcgtga tgggttacaa tttgaagata atcaaaaaga tatcatcagc
    10381 ctttacagta ttgctgaaca gtatgatatg acgtggtttg atacttatca aatagctaag
    10441 gcgacggctg ttaatgggaa aattcgacct gaacgcttat tggctaaaaa aaatcaaagc
    10501 atgacaaaac caagcaaaga aaatttttca caggctgagc aaattatttt gcgagaagca
    10561 aagcaagaca gtgctttagt ctttttggaa aaaattaaaa aggctagacg tgcaacgatt
    10621 actaaggatg aacgcatttt attgcaaaca ttggccaaaa tgaattttct tgatgatgtt
    10681 atcaatgtca tggtgcttta tacctttaat aagacaaaat ctgctaattt acagaagagt
    10741 tatgtcttaa aaatggccaa tgatttcgcc taccaaaagg tgtcaacggc tgaagaagct
    10801 atagtggttt tgcgagcctt cacggatcgt caaagtcgtc ggcaatcaaa agtaaaaaca
    10861 agtcaaagta atgtgcctaa gtggagcaat cctgattacc aagagacaac aagtcaagaa
    10921 gagcaggcga aactagatca gttcaaacag gctgctttga agaggttaga aaacctagga
    10981 aaagggggtg actagatgga aaagattgga gaaaccatgg cgaaattggg tcaaaacact
    11041 cgtgttaata gcgaccagtt gattcaaacc attttagcgg atcctgaagt agcaagcttc
    11101 atcagtcaac atcacttatc tcaagagcaa attaacctta gcttatctaa gttcaatcaa
    11161 tttttggtgg aacgccagaa gtatcaactc aaagatccct cttatattgc taagggctat
    11221 cagcctattc tagctatgaa tgagggctac gctgatgtgt cttatttgga aaccaaagaa
    11281 ttggtagaag ctcaaaaaca ggcagctatc tctgaacgga ttcaactggt tagtttgcca
    11341 aaatcctatc gccatattca tttatcagat attgatgtta ataatgcgag ccgtatggaa
    11401 gccttctctg ctattttaga ttttgtggaa caatacccat cagcagagca aaaaggctta
    11461 tatttgtacg gagatatggg aattggcaag tcttacttgt tggctgctat ggcccatgaa
    11521 ttgtctgaga aaaaaggtgt gtcaacgacc cttctacatt ttccgagctt tgccattgat
    11581 gtaaaaaatg ccatttcaaa cggctctgtt aaagaagaaa tcgatgcggt caaaaatgta
    11641 ccagtgctca ttttagatga tattggtgca gagcaagcca cttcttgggt ccgtgatgag
    11701 gtgttgcagg tgattttaca ataccgtatg ttagaggaat tgccaacctt ctttacctct
    11761 aattacagct ttgcggattt ggagcgaaaa tgggcaacca tcaaaggaag tgacgaaact
    11821 tggcaggcca aacgtgtcat ggaacgcgtg cgttatttgg ctagagagtt tcatttagaa
    11881 ggggctaacc gccgttaagt ttgagatagc aatcaagaag aatagctaca cgtatgagtg
    11941 agtgaaagaa aaggagaatc atggttttac ctaccgttgc cattgtgggc cgtccaaatg
    12001 tgggcaagtc caccttattt aatcgaatcg caggagagcg catttcaatt gtagaagacg
    12061 ttgaaggggt tactcgtgac cgtatttatg ctactgggga gtggcttaac cgccaatttt
    12121 cattgattga tacaggtggt attgatgacg ttgatgcccc gtttatggag caaatcaagc
    12181 accaggctca aattgccatg gaagaagctg atgttatcgt ttttgttgtt tctggcaaag
    12241 aaggggttac ggatgcagat gaatatgtgt ctaaaatcct ataccgaacc aatactccag
    12301 tgattttagc tgtcaacaaa gtggataatc ctgaaatgcg taatgacatt tatgattttt
    12361 attcacttgg tttaggagat ccctatccag tttcttctgt tcatggtatc ggaacagggg
    12421 atgtcttgga tgcgatcgtt gaaaacttgc cagtagaaga ggctgaagaa aatgatgata
    12481 ttattcgctt cagtttaatc ggtcgtccta atgttgggaa atctagcttg attaacgcta
    12541 ttttaggtga ggaccgtgtt atcgctagcc ctgtcgcagg gacaacacgt gacgctattg
    12601 acacgcattt tacggatgct gacggtcaag aatttaccat gattgacacg gctggaatgc
    12661 gcaaatctgg caagatttac gaaaatacag agaaatattc tgtcatgcgt gccatgcgtg
    12721 ccattgaccg ctccgatgtg gtcttgatgg ttatcagtgc tgaagaaggt atccgtgaat
    12781 acgacaagcg tatcgctggc tttgcacacg aagctggtaa aggaatgatt atcgtggtta
    12841 acaaatggga taccattgac aaggataatc ataccgttgc taagtgggaa gccgatattc
    12901 gtgaccaatt ccaatttttg acatacgctc cgattatttt tgtgtcagct ttgacgaagc
    12961 agcgcctcaa caaattgcct gacttgatta aacgtatcag tgagagtcag aataaacgta
    13021 tcccatctgc tgtcctcaat gatgttatca tggatgctat tgccattaat ccaacaccaa
    13081 cggataaggg taaacgtttg aaaattttct atgccactca agtgtcagta aagccaccaa
    13141 catttgtcgt ctttgttaac gaggaagaat tgatgcactt ctcttatcta cgcttcttgg
    13201 aaaaccagat tcgcgcagcc tttacctttg aagggacacc gattcatctg attgctcgca
    13261 aacggaaata agaaatgaac atcaactaaa atgctgacct aagaaataat ctcatcattg
    13321 ataaggactg tgttgtgtat gttacaggag acagtccttt ttataatacc tttaagggtg
    13381 tagacggaag attagtagca aacaaagaaa aaggattttg acaagaaata tcagtcggtt
    13441 tttgctataa tgaaaggata agcaaaaagg tggaaaaatg atggctagat taattccagg
    13501 acgagtaagg aatgaaggta ttaagcttta tgagcaaggt ttagtctcat tccaagatga
    13561 taataaaggc attcttcaaa tagaagtgga gacttatcag gttcaatatg gagcagatga
    13621 tgaggatatc acttgtcaat gcgacacatt tcatatgaaa cattattgca agcatattgc
    13681 agcagtcgag tattttttaa aaaatgatca aaaaggtaag ctttttttaa aacagttaac
    13741 aaatcaaaca aaaatcaaag aaacaacaaa gaaaatgaca tcttttggta gcctcttttt
    13801 agatagctta gccatgaatg aagatgattc tgttaaatac aggctgtctg ctcttggtag
    13861 tcgaagccct ttttcgtcag attactggtg gagtctgaaa atcaatcgtt taccagatga
    13921 tcgttcttat gtgattcgag atattaaagg ctttttgcag cttattaaaa aagaaggctt
    13981 ttatcagatt ggaaaaaatt attttgaaca actttcatgg ctgcagtttg acccatccag
    14041 tcaagacctt attgagtttt tatggcgctt agcatctgat actgacaaag gggacaacga
    14101 gaacattttt ccaaatcatg caaggcattt gcgcttacct agtggttttt ttgaagaagg
    14161 cgttcactat ttgacgtcac tttatgattt tacttttgag gggccttctc aaacttatca
    14221 tcatcttttt gtccgttctt tggaagcaga ggcaggcctt tatgagttta aagtggaagt
    14281 gcatcgcaaa tctattgaat tgcaaattgc tgaaaaaaat gtgcaatacc tctttgataa
    14341 tgactatctt ctttatcaag atacctttta tcacttgacg ttaaagcaac gaaaaatggt
    14401 tcaggctatt cgtagtctgc ccattgaggc cgacttggct aaacatattc attttgattt
    14461 ggatgatcat gcgaaattag ctgcaagctt atcagatttt aaacagatcg gtctagtaga
    14521 ggctcctaaa agctttgcta ttagagactt tgaggtgact tttcaatttg atttgttaaa
    14581 tcgagatgaa atcagttgtc agcttatgtt tgattatggc aattaccaag ttagtgacaa
    14641 agcaagttta gaagcacttc cttttgctag tcatttaaaa aaagaagaaa aaatcaatcg
    14701 ttctttactt gcttttggct tctcgccaca attttactca aaaaagcgac taacaagtgc
    14761 aaaagagctc tatacttttt ttgaagaaac agttccatgt tttgagcgct taggtaatgt
    14821 tgcgttgagt acagctatcc aagcattaca agtgaaagaa atgcccaaga tcgctattag
    14881 acgcaatcag ggattactag atatttcgtt tgatttttca actattattg aaaatgatat
    14941 tgaccaagct gttacagctc tttttcaaaa taatccttat tttgtgagtc aaacaggtca
    15001 attagtggtt tttgatgatg aaactcaaaa agttagcaaa agtttacaag aattaagagc
    15061 aagacagcta aaaaatggtc acttgcaact ggatggcatt agagctctac aagtatccaa
    15121 actttttgaa ggcatgacat ctgttcattt ttcaaaggaa ttagaagagt tagcctatca
    15181 tttgcagcat cctgaaactt tttcaataaa accgttacca gttaaggctc aaatgcgaga
    15241 ttatcaacgc aacggtgttc agtggttatc aatgctcaat cattatggct ttggtggcat
    15301 tttagcagat gatatgggac ttggaaaaac tctccagaca cttgcttttt tagctagtca
    15361 cctgaaatca gatagtaaag tgctcatttt atctccatct agtcttatct ataattggtt
    15421 tgatgaatgt caaaaattca cacctcagct agatgttgtg gtttcttacg gacttaaaca
    15481 aatcagagat caaatcatcg aagaaggtca tcaaataacc ataaccagct attcctcctt
    15541 tagacaggat tttgagacct atcaagcgtt tcactacgat tatcttatct tagatgaagc
    15601 tcaagtgata aaaaatgcac aaactaagat ttcacactgt ttacgtgcgt ttaatacagc
    15661 caattgtttt gcgctttcgg gcactcctat tgaaaataaa atgcttgaaa tttggtccat
    15721 tttccaaatt gttttgccag ggttgctacc gactaaaaaa gagtttttaa aattaacagc
    15781 tgagcaagta tcacgctata tcaaaccctt tgtgatgcgt cgtaaaaaag aagatgtcct
    15841 accagaatta cctgatttaa ttgaaactaa ttattcaaac gagatgacag atgaacaaaa
    15901 agctatttac ttagcgcagt taaggcagat gcaagatcaa attcgaaatt ctagtgatgt
    15961 ggatattagc cgtcaaaaaa ttgagatttt atctggtatc actcgattga ggcaaatctg
    16021 tgacactcca agtctcttta tggattacca aggcgaaagt ggtaagctag atagtttgcg
    16081 aatcttattg acacaaatta aagaaaatgg tcatcgggct ttgatttttt ctcaatttag
    16141 agggatgctg gacttggcca agcaagagat gactgctcta ggattgacct cttatcaaat
    16201 gacgggatct acccctgcca atgaacgtca agaaatgact agagccttta ataacggttc
    16261 caaggatgct tttttgattt ccctcaaggc aggtggagtt ggaatcaacc ttacgggagc
    16321 agacacagtg attttaatcg atttatggtg gaatcctgct gttgaaatgc aggcaattag
    16381 tcgcgcctac cgtattggtc aaaaagaaaa cgttgaagta tatcgcttaa tcactcgagg
    16441 aacgattgaa gaaaagattt tagagcttca agaaagtaag cgcaatttgg tgactacagt
    16501 tttggatggc aatgaaagcc gagcaagtat gtccattgaa gaaataaaag aaattttggg
    16561 gctaaacact cattaatctt ccttgatttt agtgacatta aaaacccttt aaagaagatg
    16621 acaccaaaag caccttatat aatctcgtta aaacgcttct ttttgaaata tctttattga
    16681 tatagcgatt tgtcatttgc tagtaatgat taaaacattt agaaaaagac aagtcataga
    16741 atcatcaagg aatgctttga aaaataacag tatttaagtt ataatagagg atgctacaag
    16801 aagggagaat caaaaaagga tggtaaaaaa tcagtttcct ttagttgcag atggcattgc
    16861 tattagtgat ccagcaaagc aaatggctct gtatgaaaat gaagatctca ttaccaacat
    16921 ccgtggctat taccaggaca aggagtatga tgatattgct agaaatgagg agtttactgc
    16981 taaagcaact tctcggcagg ccccttctag taagcgcttt tgtagcaatg atgaaaaaca
    17041 ccattatgtc aaagaggcgc gtcaaaaagc aaagcaagat ctcaaggaaa aaagacaggc
    17101 ttatcttgcc aaagaaatgg cctatgttcc taaacaggtt tctaaaaagc aacagcctgc
    17161 ggattcttct ccttctcaaa agcaagcaac aacagaaatg agtcgtttta caaaaaagct
    17221 tcatcaagac aactatattt tagctgagtt gccaaaagaa tataaagagc caaaaaatct
    17281 tcctcaacaa ggaactacaa aaaaaaataa ttacgatttt ttaaaatcca gtcaaattta
    17341 caataataaa gaaatgagac aacaacgaga aaaaacaatt gcgcaagagc ttaatcttag
    17401 taggtttgag gatcttcctt aataaatcta ctcagcgtat gcagatgaca aaggagttaa
    17461 gatgtcaaaa acgtatcatt ttatcggaat taaagggtca ggaatgagtg ccttggccct
    17521 tatgttgcat caaatggggc ataaggtgca aggtagtgat gttgaaaaat actatttcac
    17581 tcaaagagga ttggaacaag cgggcatcac tatcttacct tttagcgagg acaatattac
    17641 gccagatatg gaacttatcg ttgggaatgc ctttcgtgaa aacaacaaag aagtggccta
    17701 tgctttgaga caccagattc ctttcaaacg ttatcatgac tttttaggtg attttatgaa
    17761 atcatttatc agttttgcag tagcaggtgc tcatggtaaa acttctacaa cgggtttatt
    17821 gtcacatgtc ttgaaaaata tcacagacac atcttattta attggtgatg gtactgggcg
    17881 tgggtctgct aatgcgcagt attttgtttt tgaatcagac gaatacgaac gccattttat
    17941 gccttatcac ccagaatact ctatcattac taatattgat tttgaccatc ctgattattt
    18001 cacaggaatt gctgatgtgc gaaacgcttt caacgattat gctaagcagg tcaagaaagc
    18061 tttgtttgtt tatggtgaag atgacgaact aaaaaagatc gaagcacctg cacctattta
    18121 ctattatggt tttgaaaagg gcaatgattt tatcgcttac gacattacgc gtactacgaa
    18181 cggatcggac tttaaggtaa aacaccaagg agaggtcatt ggtcagtttc acgtacctgc
    18241 ttatgggaaa cataacattt taaacgctac agcagtaatt gcaaacttgt ttgtagccgg
    18301 cattgatatg gctctagtgg cagaccatct taaaactttt tcaggtgtga aacgtcgttt
    18361 tacagagaaa attatcaatg acactattat tattgatgac tttgctcatc atccaaccga
    18421 aattgtggca acaattgatg cggctagaca aaaataccca agtaaagaaa ttgtagcaat
    18481 attccagcca catactttta ctcgcactat tgccttatta gaggattttg cttgtgcttt
    18541 aaatgaagct gacagtgttt atttagccca gatttatggt tctgcacgtg aagtagataa
    18601 aggtgaagtt aaggttgaag atttggctgc taagattatc aaaccatcac aagtagtaac
    18661 ggtggaaaat gtctctcctc ttcttgatca cgataatgct gtttatgttt ttatgggagc
    18721 tggagatatt cagctatatg aacattcttt tgaggaatta cttgcaaatt taactaaaaa
    18781 taaccaataa catgtcctgc cttaggcagg ttttctcatt ctaaaggagt ttgatatgtt
    18841 gattagacag gttcaaggat ccgatttgga agttattgct accattgaaa gtgacaattt
    18901 ttcaccacaa gaagcaacga caagagcagt tcttgaagag cgcatacggc tgataccaga
    18961 tactttttta gtggcactta tcgatcagga aattgttggc tatatcgaag gtccagttgt
    19021 cactactcct attttggagg attctttgtt ccacggggtg actaaaaatc ctaaaactgg
    19081 aggctatatt gctattacta gtttgtccat agctaaacat tttcagcaac aaggggttgg
    19141 gacagctttg ttggcggcac taaaagattt agtagtagcg cagcaaagaa caggtcttat
    19201 tttgacttgt catgattact tgatttccta ttatgaaatg aatgggttta ttaaccaagg
    19261 aatttcagag tctcaacatg gtggaaccct ttggtaccaa atgatttgga aactttagaa
    19321 tcacagctga ttcaactgtt ggtttgttaa aaataagtaa caaatgcatc atttaattgc
    19381 aattaggata cttttaagtt ataatggcgg ttgattatat ttaggaggat tggctttgac
    19441 cgattttaag gataaagacc aacaagatca gcagcgaagc tttaaagagc agattcttgc
    19501 tgagttggaa aaagcaaatc aaatcagaaa agaaaaagag gaagaacttt ttcaaaaaga
    19561 gttggaagct aaagaagcag ctaggagaac ggcccagcta tatgctgaat ataaaagaca
    19621 agatgctttt caaaaagagt ctatagcaca taacaataag acagctaaac actttcaagc
    19681 tataaaagat gcggtaatga cttcagaagc gcttaaaccg actttacttt ctgaaaaaga
    19741 aaactcatct ttaaaaacga caaataagag agtcgtgcag gcaaatgagc ttcaagagac
    19801 tgcctctaaa gaatctcaag taccgttaac tattgagaaa ggtcattcag tgagacgaaa
    19861 attaagtaaa cgccaacaga ctgagcgagc tgctaaaaag atttcaaccg ttttgattag
    19921 ctctattatt ataacccttt tggcttttac tctagcagga gcaggctatg tttatagtgc
    19981 tttaaatcct gttgataaaa atagtgatgc ctttgttcaa gttgagattc catctgggtc
    20041 aggcaataaa ttgattggtc aaattcttca aaaaaaaggt ttaatcaaga atagcactgt
    20101 ttttagtttt tatacaaaat ttaaaaactt tacaaatttt cagagcgggt attacaatct
    20161 gcaaaaaagt atgagtctag aagaaattgc tagtgcttta caagaaggtg gtacagcaga
    20221 acctaccaag ccatctcttg ggaagatctt gattccagaa ggatacacga ttaaacaaat
    20281 agctaaagct gttgagcata atagcaaggg aaagaccaaa aaagctaaaa caccttttaa
    20341 cgagaaggat tttttggatt tagtcacgga tgaggctttt attcaagata tggtaaaaag
    20401 atatccaaaa ttattagcaa ctatcccaac taaagaaaaa gctatttacc gtttggaagg
    20461 ttaccttttc ccagcaacct ataactatta caaagaaact accatgagag aacttgtaga
    20521 ggacatgctg gcagctatgg atgctacttt ggtaccctat tatgataaaa ttgctgctag
    20581 tggtaagaca gtcaacgagg tattgacctt ggcctctttg gttgaaaaag aaggttcaac
    20641 agacgatgac agacgtcaaa ttgcaagtgt cttttataac cgccttaata gcggaatggc
    20701 actacaatct aatatagcta ttttgtatgc gatggggaaa cttggtgaga aaacaacctt
    20761 ggctgaggat gctactattg acaccaccat taattctcct tataatattt ataccaatac
    20821 aggtctgatg cctggtccag ttgctagctc gggggtttct gcaattgaag caaccctaaa
    20881 tccagcctca acggattatt tatactttgt ggccaatgtc catactggtg aagtttacta
    20941 tgcaaaaaca tttgaagagc actctgcaaa tgttgaaaaa tatgtgaata gtcaaattca
    21001 gtaaacacaa acatggtgct taagcaccat gtttgtgttt ctgattcgtt caaaaaagaa
    21061 aagagagaaa acaattatgg cagaaaaaac gtatccgatg accctaacgg aaaaagaaca
    21121 acttgaaaaa gaacttgaag aattaaaact tgtgcgtcgt ccagaaatag tggagcgtat
    21181 taaaattgca cgttcgtatg gagatctttc agagaactct gaatacgatg ccgcaaaaga
    21241 tgagcaagct tttgttgaag gtcaaatttc aacgcttgaa actaagattc gctatgctga
    21301 aatcattgac agtgatgctg ttgcaaaaga tgaagtcgct atcggaaaaa cagttatcgt
    21361 tcaagaagtt ggaacaacag ataaagatac ctatcatatt gtaggtgctg ctggagcaga
    21421 tatcttctcc ggaaaaattt caaatgaaag cccgattgct caagctttga ttggtaaaaa
    21481 aacaggtgac aaggttagaa ttgaatcacc agcagctact tatgatgttg aaatcatcag
    21541 cgttgaaaag acaaattaat ccgatgaagc cattatttgc ctaaccacta agtgttttgg
    21601 ttgctaatgg cttttctagt atcttcaaat gaggttgact gttaggaagg tcaagtatta
    21661 atcgcattga ttatgagcca agaggactat agatcaaaga tcgttttcga tggttattta
    21721 ataccaaaag aaaagaccag caccttaatg tactgacccc aaaaagttgg acactatatt
    21781 ttaagtatag gaagtgtata atctaaggaa actgacacta atcattgacc gttttgcaag
    21841 actttattaa tgatttcttg ctttatttta aatgaataag tctgatacgt ttccttcctt
    21901 aacactatcg actccataat gacccatcag tcaaacggta tatctcaaac gactacggtt
    21961 tactccaaat tcattggcta gttgaggcca agaaacacct gattttttta atgctaaatt
    22021 tctagcttat cttcatagct taatttcata caaaaacacc ccaatcgtta gatttttttg
    22081 atatgtcccc tttcactaga tgagtccagt aaaagggggc atatcgtttt ttgtctaact
    22141 tttggagtgc agttcataat tgtgctaggt tttttgtctt tcttaacgct ttcgctgttt
    22201 tccagcatta cgattggatt ttattttttt aggcaagtta gcctgttcca tgttttgtga
    22261 aggcgtaacg tccttacgag aagaagttga ttggtatgct ttaggcgggt ttttagcgta
    22321 ttcttcttta atttgcttat gcaatcgagg ttttaagagg taggttgtga ttaactgttg
    22381 aataatacta aagaaaccac caactagcca gtaaagacca acgccagcag ggagtgagaa
    22441 ggacatgaag atcatcatga taggcatggt gtacatcatc gtcttcattt gctcacgttg
    22501 ttcttctgaa acggccatca ttgataacca tgattggaag aagtaaagag cagcgataat
    22561 tgctgttaac actaaactac ggctaccaag atcaatgctc ataaaggtac ttgttgatac
    22621 tcctttagtg tattgagcgg caaaatacat ggcagaaaag aatggcatct ggatgagaag
    22681 aggtagacat ccaatacctc caagagggtt aatcccatga gcacgctgag cagccatcaa
    22741 ttctgtttgg gcagccattt tttcttcctg actacttgcc tgtttgatac gtttgttgat
    22801 tggttcaaaa acaggtttca agaaggtcat tttctcagat tgataacttg ctttccaaga
    22861 ttgatataga cctagtggta agataagtgt tctaacaata atggttacga tgatgatagc
    22921 cagtccataa cctagtccag cattgtttgc aaagtaatcg ataaagtatg acatgggttt
    22981 tccaagaaat tcccaaatca tacctttggg atttccgtga gcgtctcttc ccacacagcc
    23041 tgtcaaggtg aatagaattg acagtgctag tcctgaaaat aggatgcgat ttaatgttag
    23101 tttcaatgtg tttatccttt aattttaata tacttatcta ttttacagtt tttttcagaa
    23161 attcacaata gttctgaagg ccgattttta attgcctatt tgaaagtcct gaaagtcttc
    23221 aaaattagcc atggtgacat ccacataagt gacttttgcc catttggatg gtcctttacg
    23281 aacttcttga ataaatgtgg ctattttatc tgaatctttt gattgggcca gaatttcaac
    23341 ggtcccatcg ttgttattcc agacacgacc ataaatacct cctatatcta gagctaaagt
    23401 atgagtagcg tatcgaaaac caacaccttg tacacgtcca gaaacaatta aacgtacttt
    23461 ttgcataaga agggcctcct tgcttttatt ataacacata cttagcagga aatctcttta
    23521 gccaattgtc tacttcctgt cacttttact aaagacaaga atacaaaaat gagatagtta
    23581 gtagtactaa cagtaaaaga ggtttgtcta ttttaaaaat agtatcaaaa aaaggtcttt
    23641 taggtttaaa acattgaact gcccccaaat tgaccatcta agaagttgat gctttcaaat
    23701 gctgtcgcgt atggtataat aggcgcatgg ttattacatc aaaagcaaat caactaatta
    23761 agcaaacaaa aaaattattg caaaaaaagc atcgaaaaca gtcctatttg attgagggtt
    23821 ggcacctttt tgaagaagcc caaaaatcag gacaagtttt tcgccacatc tttgttttag
    23881 aggaaatggt ggagcgtcta gcaggtgagc aagaactcgt tattgttagc ccacaagtgc
    23941 tcaaggagtt gaccgactct cctagtccac aaggcattgt tgctgaggtg gagataccta
    24001 agttagcctt tccatcagat tacaaaggga aatatttggt tttagaggac gtccaagacc
    24061 caggaaatct tgggaccatc attcgtacag cagacgctgc acggtttgat ggggtctttc
    24121 tttctgaaaa atcagcagat atttacaacc aaaaaaccct acgttccatg caaggtagcc
    24181 attttcattt accaatttgg cgaacagatg tctatcagct ttgtcgagag ctccaagagt
    24241 ataaaactcc catcctagca acaactctgt caaagaaatc tgttgactat aaaagcctca
    24301 cacatcatga aaggttggct ttggtgttgg gaaatgaagg ccagggcatt agtgctgaaa
    24361 tggcagccct agcagaccaa ctggttcata ttacaatgcc tggtcaggcg gaaagtttga
    24421 atgttgccgt agcagcagga atcctcattt tcagcttgat ttaagctaat atgatataat
    24481 aaccaagtga ggtaattatg ttatgcatta tacagaagat aaagaatata tggaacacgt
    24541 cggtcatttg atcgctcatc ctcgctttca aaaattgagt catattgttc agcaccaaca
    24601 ttcaacgcgt cttgaacatt ctatcaatgt ttcttattcc agttataaat tagccaagcg
    24661 atttggttgg gatgctaaaa gtacagccag agggggctta cttcatgatt tcttttatta
    24721 tgattggcgc gtgaccaagt ttaataaggg tcatgcctgg gttcatcctc gtattgctgt
    24781 acgaaatgcg aaaaagttaa cagaactcaa taaaaaagaa gaggatatca ttctaaaaca
    24841 catgtgggga gcgaccattg cttttccgcg ttacaaggaa agttatattg tgacaatggt
    24901 agataaatac tgggctgtca aggaagcagt gacgcctttg agacaaaaat ggtctaatcg
    24961 acggtttctt cgccgcaaga ccctccaaag tcataatcgt taagtaaagg agttattatg
    25021 aacgatcacg ttatttatac acaatcagat gtgggattaa atcagttttt tgctaaaatt
    25081 tatagtctag tgggaatggg agtgggtttg tctgcttttg tttcttattt gatgctttat
    25141 ccatttagag aaaatttaat ctctattctt gttaatcagc cgatgattta ctatggtgct
    25201 gcgattattg aacttatttt agtttttgta gccagtggtg cagcacgaaa aaacacacca
    25261 gctgcattgc ccatttttct tatctattct gcgctaaatg gctttaccct aagctttatt
    25321 attgtggcat acgctcaaac gacagttttt caagcatttc tttcttcagc agctgtgttt
    25381 tttgccatgt caatcattgg tgtcaagact aaacgggata tgtcaggtct tagaaaggct
    25441 atgtttgctg ctttgattgg tgttgttgtg gctagtctga ttaatctttt tattggtagt
    25501 gggatgatga gttatgtcat tagtgtgatt tccgtgctaa ttttctcagg tctcatcgca
    25561 tcagataatc aaatgattaa gcgcgtttat caagcaacaa atggccaggt tggtgatggc
    25621 tgggctgttg ctatggcctt aagcttgtat ttagatttta ttaacttatt tatcagcctt
    25681 cttcgtattt ttggaagaaa tgattaacat taaaaagtga gtataactac tcacttttta
    25741 atgttaacag gataagtaaa ctgtaagcaa gaaattcgag atagatataa gatgaggctg
    25801 ctaaaagacc tagtgttaat ttgtaaactc tttctttttt tggtatacta ttaaggatta
    25861 aatacgagga gaatatagat agatatgtca acagctattt ggattttatt acttattgtt
    25921 gcccttgggg taggtgtttt tggtgggatt tttattgccc gtaaacaaat tgaaaaagaa
    25981 attggtgaac acccacgttt aacaccagaa gctatccgtg aaatgatgag ccagatgggg
    26041 caaaaaccaa gtgaagcaaa aatccaacaa acttatcgta atatcatcaa acaatcaaaa
    26101 gcagccgtat ccaaaggtaa aaaataaaag ctaattgtta taggggaaac ctttgtgata
    26161 gttagaagtg aacagtcttt gatctcaatg ttcagtagca cttgtcttat cagttagatt
    26221 tgtcaactgt tcagggttta aaaagaaact cagttggcta tttccaactg agtttttcat
    26281 atcgtcagta aggaagtaaa gataatggat acaagaccaa ttgggttttt agattctggt
    26341 gtgggaggtc tgaccgtcgt ttgtgaattg attcgtcagc tccctcatga gaagattgta
    26401 tatattggtg attcagcaag agccccctat ggtcctagac ccaaaaaaca aattaaggag
    26461 tatacttggg agctagtcaa ttttttgctg actcaaaatg ttaaaatgat tgtttttgca
    26521 tgcaataccg caacagcggt ggcttgggaa gaagtaaaag cagctttaga tattcctgtt
    26581 ttaggggttg tcttaccggg ggcaagcgca gctattaaat caacgacaaa aggccaggtt
    26641 ggggtcatcg gaaccccaat gacagtggct tcagacattt atcgcaaaaa aatccagcta
    26701 ttagcaccat ctgttcaagt aaggagtctt gcttgcccga agtttgtacc gattgtggaa
    26761 tcaaatgaga tgtgttcgag tatagctaaa aaaatagttt atgacagtct agcaccatta
    26821 gtcggtaaaa tagataccct tgtactagga tgtactcact atcccttgtt acgaccaatt
    26881 atccaaaatg ttatggggcc atctgttaag ctgattgaca gtggagcaga atgcgtccga
    26941 gatatctctg tcttattaaa ctattttgac attaacggta actatcatca aaaagctgtc
    27001 gaacaccgct tttttacaac agcaaattct gagatttttc aagaaattgc ctcgatttgg
    27061 ctgaaacaaa aaataaatgt ggagcatgtc accttatgag tgaaaaaatt tacgaataca
    27121 aagatgaaaa taactggttt atcggaaaga tgactggtca taatttaata tcgggctggg
    27181 gagtcaaaca cacgacaatc aaaaaaatag atgacctttt agacggtatt gccgcaacgt
    27241 tagattggga aaatcctaaa ggttacgatg tttcggtggt gcgttatcag tctcctttat
    27301 ctctcatcac ctttattatc gacatgataa atcaagagac ccagcgtgag attaaggtaa
    27361 ctccccatgc aggcacgatt ttattaatgg aaaatgcgaa actgcttgca gtttatctcc
    27421 cagaaggtgg agtttcaacg gctacatttt ttgcaactag tgaacaggga tttggggata
    27481 ctattttaat cgctacacga aacgagggaa aaaccaaaga gttccgcaat ctgtttgggc
    27541 agctaggtta tcgtgtggaa aatctcaatg attatccaga attgccagaa gtggcagaaa
    27601 ctggtactac ttttgaagaa aatgctcgct tgaaagcaga aacgatttca cgtctcacag
    27661 gaaaaatggt attagcagac gattcaggac taaaagttga tgccttgggt ggtttacctg
    27721 gggtttggtc agctcgtttc tcaggaccag atgccacaga tgccaagaat aatgccaaac
    27781 tcttacacga attagctatg gtgtttgacc aaaagaagcg ctcagctcaa tttcatacga
    27841 ctttggtagt ggctgctccc aataaagata gtttggttgt ggaagctgag tggccaggct
    27901 atattgctac gcagcctaag ggagaaaatg gttttgggta tgaccctgtc tttatcgtcg
    27961 gagagactgg gcgtcatgct gcagaattag aggctgacca aaagaatcag ttgtcgcata
    28021 gaggtcaagc agttcgaaaa ttaatggagg tctttccagc atggcaagca aaacaatcat
    28081 agtaatgagt gactctcatg gtgaccgaga tatcgttcaa gccattaaag acaagtatct
    28141 tggtcaagtt gatgctattt tccataatgg ggattctgaa ttaaacagct cagatcctat
    28201 ttgggctggt atttatgtcg ttggcggtaa ttgtgactat gatacaggtt accctgatcg
    28261 tttagtaact caattaggca cagttacgat tgcccagaca catggtcact tgtaccatat
    28321 taatttcact tgggataaac tggactactt tgctcaagaa gtagcagcag atatttgtct
    28381 atatggacac ctacaccgtc cagctgcttg gcaagttggg caaaccctct ttatgaatcc
    28441 cggatctgta acacaacctc gcggagaaat taacgagaaa ttatatgctc gtgttgaact
    28501 aactgatact caaattaaag ttgattactt tacaagagat cataaacttt actcatcact
    28561 gtctaaggaa tttaaacgat gatcgcaaaa gaatttgaaa cgtttttaat gagtcattta
    28621 gataattatc ttatcccgga acaagacttg gctattttta tcgacacaca taatgcagac
    28681 catgtgatgt tactattggt gagcaatggt ttttctagag ttcctgttat cacacgggag
    28741 aaaaaatatg tgggaaccat tagcatctca gatattatga tgtaccaatc taaaaggcag
    28801 ctgacagatt gggaaatgag tcaaacagat attggcgaga tggttaatac caaaattgaa
    28861 accattagca ttacttctag cctaacagaa attatgcaca agttaattga tttcccattc
    28921 ttaccggttg tagatagagc gaaccgcttt gttgggatta ttacgcgaaa atctatatta
    28981 aaggctgtca acagtctttt acatgatttt acagatgatt acacgattat aaaaaaatga
    29041 agagttatat tgaacctttt attgctagca aggctttatc tcaaaatagt caaaaagctt
    29101 atcgatacga tttgcaacag ttttgtcaac tggttggtga acgtgtcaat caagacaaac
    29161 tattacttta tcaaaatagc atagctaacc taagtttatc tgcaaaaaaa cgcaaattat
    29221 caacagctaa tcaattctta tattacttgt atcaaataaa gtatttaaat agttattttc
    29281 gattaacaga taccatgaaa gtgatgcgga ctgagaagca gcaagctgct attattaata
    29341 ctgatatttt ctatcaaaaa accccttttg tgtgggggca attaatcagc ttattaatat
    29401 tggagctggg tttaactccg agtgaagtag ctggtattga agtagctaac ttggatttaa
    29461 attttcaaat gttgacgcta aagactaaaa aaggtgtgcg tgtattacct ttgtcgcaaa
    29521 tactaatccc ttttttagaa caacaactcg ttggcaaaga agtctatctt tttgaacatc
    29581 gaggcatccc tttttcaaga caatggtttt ttaatcacct aaaaaccttt gttcgaagta
    29641 ttggttatga aggattgact gctcaaaaat tacgagagca atttattttg aaagaaaaac
    29701 tagctggtaa atcgataata gaacttagcg atattcttgg gctgaaaagc cctatgacct
    29761 tagaaaaata ctacaaatca taatggatat aaaacttaaa gattttgaag gtcctcttga
    29821 tttactcttg cacttggtat cacagtacaa agttgacatc tacgaggttc ctattgttga
    29881 ggttattgag cagtacctta attatattga aaccttacag gtaatgaaac ttgaagtggc
    29941 tggtgactac atgctgatgg caagtcagct catgttaatc aaaagtagaa ggctattacc
    30001 aaaggtggta gaacacatcg aagaagaaga tttagaacaa gatctgttag aaaagatcga
    30061 agaatatagt cgctttaaag cagttagtca agcgttagcg aagcaacatg accaaagggc
    30121 aaaatggtat tcaaaaccta aacaagaatt aatttttgaa gatgctatct tacaggaaga
    30181 taaaacggtg atggatctat ttctagcttt ttcaaacata atggcagcta aaagagcagt
    30241 tttaaaaaac aaccatacag tcatcgagcg tgatgattat aagattgaag acatgatggc
    30301 ttctattaaa cagcgactgg aaaaagaaaa cgttattagc ttatcagcga tttttgagga
    30361 atgccaaaca ttaaataaag ttatcagtat atttttagct agtctagaat tgattaagct
    30421 tcacgtggta tttgtagagc agctctctaa ttttggggct atcatactac gaaaggagaa
    30481 gaaatgacgt atttgtcaca gatagaagcg ctgctatttg ttgcaggtga agaaggatta
    30541 agtttgcgac atctagcgtc tatgttatca ttaacgccaa cagctcttca acagcaatta
    30601 gaaaaactct ctcaaaagta tgaaaaagat caacattcta gtctttgctt gatagaaaca
    30661 gctaatacct acaggctagt aactaaagaa ggttttgcag aactcttgcg tgcttatgcc
    30721 aaaacaccaa tgaaccaaag tttatctcgt gcgagtttag aggtcttgtc tattgttgca
    30781 tacaaacaac ctattacacg aatagaaatt gatgacattc gaggggtaaa ctccagtgga
    30841 gctttgagta aattattggc atttgatctc attagagaag ctggcaaaaa agatgtggtt
    30901 gggcgtcctc atttgtatgc gacaacagat tattttctgg actatatggg aattaatcat
    30961 ttagacgaat tgattgaagt atctgccgtt gaaccagcag atgaagagat tgctcttttt
    31021 aggacacaag actgagtttt gcttgtcatc aaatagcaaa tggcgtttac aaaaggattt
    31081 gttttaaggc gttttagttg aaaaaagcct taaactaggg acaacaaaaa gttgctcaaa
    31141 agaaagaaga atataatgcg aattaacaaa tacattgccc atgcgggtat tgccagtcgt
    31201 cgtaaggctg aagaattgat taagcaaggc ttagtaacct taaatggtca ggttattacg
    31261 gatttagcaa ccactgtaaa atcgggagac gtggttgaaa tagaaggaag tcctatttac
    31321 aacgaggaaa aggtttacta tttgcttaat aaacctcgtg gcgctatctc aagtgtgtca
    31381 gatgacaaag gccgtaaaac ggtactggat ttactacctc aggttaaaga acgcatatac
    31441 cctgttggac gattggattg ggacacatca ggggtcctta ttttaacgaa tgatggtgat
    31501 tttacagata ctatgattca tcctagaaat gaaatagaca aggtttatct ggcgcgtgtc
    31561 aaaggaattg caacgaaaga aaatcttcgt cccttaactc gaggaattgt tattgatggt
    31621 aaaaagacca aaccagctcg ctacaatatt gttcgtgtag aagctgataa gaatcgatcg
    31681 attgtagaat tgactatcca tgaagggcga aaccatcagg ttaaaaaaat gtttgagtct
    31741 gtggggcttt tggttgataa attatctcgt acacgttttg ggaccgtcga cttaaaggga
    31801 ctaagaccag gagaagcaag acgcttaaat aaaaaagaaa taagtcaact gcataactta
    31861 gctaatacga aaaaatgatg aaaaaactat taatagtatc tgttaaagct tatcaaaaat
    31921 acatttctcc tttatctcct cctagttgtc gctacaagcc aacctgttca gcttatatgt
    31981 taactgctat tgaaaaacat ggtactaagg gaatactaat ggggatagca agaatattaa
    32041 gatgtcaccc ttttgttgct ggtggtgtcg atcctgttcc agaagatttt agcctaatga
    32101 gaaataaaaa cacgtctaaa aacgctgaaa aggcatgact ttatcaaaaa atggcttgac
    32161 attgatagct gaagtgttat aatggaaaac aagcattcgt tggtttaaat caaacctgtt
    32221 atgatttaag ttagcgagtc accatcaacc acattgtttg ctgagcatga ctccgagcag
    32281 tgtggttttt taaattaaaa agagtaaatg agattatgac gacaaaagaa cttatcaaca
    32341 aaaacgacaa agtaaaaaag gctcgcaatc atattgtcct gtttcaaccc caaattccac
    32401 aaaatactgg taatattgct agaacatgtg ctgcaactaa tgcaccttta cacattatta
    32461 aacccatggg atttcctatt gatgaccgca aaatgaagcg tgccggcttg gattactggg
    32521 acaagttaga actgcatttt tatgatcatt tagaacagtt tatcaatcaa tgtcacggac
    32581 agcttcacct gattagcaag tttgcagtta ataattattc tcaagctact tatgctgatg
    32641 gcgattccca ttatttcttg tttggacgag aagatacagg cctgccagaa gattttatgc
    32701 gagaacatgc tgaaaaagca cttcgtattc cgatgaatga tgagcatgta cggagtttaa
    32761 atgtctcaaa tacggtttgt atggtgattt atgaagccct tagacaacag ggctttcaag
    32821 ggttagagtt aaagcatatt tacgaacacg ataaactaaa ataatggact ttttaaaagc
    32881 gtcagttttt ggcaacatgc gttgtcagta gctgacgctt ttaaaaattt agtcaaagct
    32941 attgctatct aggtttaaat ctgctatgct agaagtgtct tcagggcagg gtgtgattcc
    33001 cgaccggcgg tgactaggta actagaagtc cgcgagcgca agctgatgtg gtgtaactcc
    33061 acaaccgaca gtatagtctg gatgagagaa gaccgggctt tttgtgtagg cttattttag
    33121 ctacacaata acgacggaac ttctttcaat ttgaaaaaat tggaggaatt ttttaatgtc
    33181 aaaaacacat aaaatgatta tgattggtat actttctgcg atatcatttc tattgatgct
    33241 agttagcttt gccattattc caggcgcagc ttttttaaaa attgaattta gtattattcc
    33301 tgtcttattt ggtttaatga ttatggactt aaagagtgct tacttgattt tgttattgag
    33361 gtccttattg aaactctttt tgaacaatcg tggggttaat gattttattg gtctcccaat
    33421 gaatattatc gctatcgctt tatttgtgac ggcttttgcc ttagtttgga accgtcaaaa
    33481 aacgcttagt caatatgtat ttgctagctt actaggcaca gggttattaa cgtttggcat
    33541 ggttgttctc aattatactt ttgccattcc tttatatgct atatttgcaa atattgatat
    33601 cagagcttat attggtgtta ctaagtatat gatgactatg gttattccgt ttaatcttgt
    33661 tgaggggttg atatttgcaa ttacctttta ttttgtgtat attgcaagta aaccaatttt
    33721 agaaagatac ttacactaat atgatgacaa acaaacaaac tcacttttta atagcttctt
    33781 ttgcattgct aatctttgtt ataataggct atacggtcaa attttttcct gaacgtttgg
    33841 cacttctaga taatactatt caagcagaga ttagaggcaa ccttcctata gtgctgacgc
    33901 aattctttag gggtgttact gtatttggaa atgtcatgac acaagttttg ttagttattg
    33961 tgtcggtcct agttttattc tttatgaagt ggaaaattga agctttgttt atcttatcaa
    34021 atggtgccat tgcagcattt ttgattacga ctctcaagct cttttaccaa agaccaagac
    34081 ctgctattga gcatttggtt tatgctggtg gctattcgtt tcccagtggc catgcgatgg
    34141 gtagcatgct gatttttggt agcctattga ttatttgtta tcagaggcta cattcaaaac
    34201 tattacaatt tgtgactagc atgatcttta taatactaat tttattaatt gggttatctc
    34261 gtatttatct aggagtacac tacccaagtg atattttagc aggctttgta ttaggatttg
    34321 gtattttgca ctttatttat cctttttata agcaaaaacg atttgaatgg cgatttcttt
    34381 tgaaacaaga ctaatttttc ttgagaagac atagggctta tttaaatcat ttagaataac
    34441 attggcaagc atcacccctt gattgccagt gttattttag ttttagttag atgatgtgag
    34501 ctgataatta gtaaatacgt ttagataaaa aacgattaaa gtgctatgta acgtcagaaa
    34561 agacatgatt tttgttgatc tgtaatcatt aagtaagctg atgtagaagt agtgaattct
    34621 aatgactgag ctatcttttg catagatgac tatcttgcta gtaatgattt gtgctacaat
    34681 agaaacatga aaaaaagata tcagacatta aacgagcatt accgtcaact atttggcgca
    34741 aaaatgttta aagttccgat tgatgccggc tttgattgtc ccaatcgtga tggaacggta
    34801 gctcatggag gatgtacttt ttgcacagta tcaggttctg gagatgctat tgtagcacca
    34861 gatgctccaa ttaaagagca attttataaa gaaattgatt ttatgcaccg taaatggcct
    34921 gatgtcaatc gctatttggt ttattttcaa aactttacca atactcatga tacagttgat
    34981 gtgattcgcg accgttacga acaagctatt aacgaacctg gagttgttgg tattaatatt
    35041 ggcacacggc ctgactgtct accagatgat accattgctt acttagcaga attatcagaa
    35101 cgcatgcatg tgacagtgga gctaggctta cagacaactt atgaagaaac ttctaggcta
    35161 attaacagag cacattctta tgatttgtat aaagaaacgg tgaggcgact aaggcattac
    35221 cccaacatta atattgtctc gcacttgatt aatggattgc caaaagaaac tcatgacatg
    35281 atgcttgaaa atgtgagacg ctgtgtaaca gataatgaca ttcaaggaat taaattgcat
    35341 ttgctgcatt tgatgaccaa tactagaatg caaagagatt atcatgaagg acgcttaaag
    35401 ttgttgagtc aaaaggacta tgtttcgatt atttgtgacc agctagagat tatccctaag
    35461 catattgtga ttcatcgtat tacaggagat gccccacgag atatgttgat tgggcccatg
    35521 tggagtctaa ataaatggga agtattgaat gccattgata aagaaatgga aagacgagga
    35581 agctttcagg gctgtaaagt tgactaattt gtctcatttt gacggatttg gataggagaa
    35641 aagtgatgct aaaacgcccc attcatctct cgcatgattt tttagcggag gttgtggata
    35701 agtctagtgt ggttgttgat gccacgatgg gtaatggaaa tgatactgcc tttttggcac
    35761 aattagctaa aaaggtttat gcttttgatg tgcaagaaca agctattaga aaaacaagtg
    35821 agcggttagc gcagctagga ttatcgaacg ctgagctgat tttagcgggt catgaagcgg
    35881 ttgatcagta tgtgacagag ccggtgcgcg cagcgatttt taaccttggt tatttgccca
    35941 gcgcagataa atctattatt accttaccaa ataccacact ccaagcttta tcaaaactac
    36001 taacgttatt aatggtaggt gggcgtattg ctattatggt ctattatggg catgatggag
    36061 gcagtttgga aaaagatgct ttattagatt ttgtcaagca attagaccaa agaaaggttt
    36121 ctgcaatgct ttatcagcct cttaatcagg tgaatacccc acctttttta atcatgttgg
    36181 agaaattagc agacgtttag ctcttatccc tgtgtcaagt ctactagaag ttctgcgatt
    36241 atttcggtgg aaaaagaaga aatcccatag gctttggcta taaatgtgat ataatgaagt
    36301 cactatatta tttttttagg agttacatta acatggaaga ccctgtgagt cagcccttag
    36361 tgattcaatt tttattgtta gttgttttaa ccttgttaaa tgcttttttt tcagccagtg
    36421 aaatggcctt agtttctctc aatcgttctc gggtggaaca aaaagcagca gacggtgata
    36481 aaaaatacgc tcgtttgttg cgggttttag aggaacctaa tcatttttta tcaacgattc
    36541 aagttgggat tacctttatt agtttactat caggagcaag tttatcagct tctttgggta
    36601 aggtgatctc aggttggcta ggtaattcag cgaccgcaag gacagctggt actatcatct
    36661 ccttggtttt cttgacttat gtctctattg ttttaggaga attgtatcca aaacggattg
    36721 ccatgaacct caaagacaag ttggcgattg tttcagcccc tattatcatt gggttaggga
    36781 gactggttag tccctttgta tggctcttat cagcttctac taatttgctg agccgactta
    36841 cccctatgac ctttgatgat gcagatgagc aaatgacacg tgatgaaatc gagtatatgt
    36901 tatcaaaaag tgaggcgacc cttgatgctg aagaaattga gatgttgcaa ggagttttct
    36961 cacttgatga aatgatggcg cgtgaagtca tggtcccaag gaccgatgct ttcatgattg
    37021 acattaacga tgatccgctt gaaaatattc aggaaatctt aaaacaaagt ttttcacgca
    37081 ttcctgttta tgatgtggat aaagataaaa ttatcggtct catccacact aagcgtctct
    37141 tggagtcagg tttccgccag ggatttgatc agattaacat gcgaaaaatg ttacaagaac
    37201 ctctttttgt tcccgaaacc atttttgtag atgatctctt acgccagctg cgcaataccc
    37261 aaaatcagat ggctattttg ctagatgaat atggtggtgt ggcaggactt gtgactttgg
    37321 aagacttgct tgaagaaatc gtcggtgaaa tcgatgatga aaccgataaa gcagaacaat
    37381 ttgttcatga gattggagac aatacctata ttgttgttgg taccatgact ttaaatgagt
    37441 ttaatgacta ttttgatacc gaactagaat cagatgatgt agataccatt gctggttttt
    37501 atttgacagg tatcggaacc attccaagcc aggatcaaaa agaagcctac gaaatagata
    37561 acaaagacaa acatttagtt ctaatcaacg ataaagtcaa agatggccgt attacgaaat
    37621 taaaattaat cctgtctaat atagaacaga ttattgagga agactaggct ccatgcctag
    37681 tctttttgat gaaaagtgtt ataatgaaaa tgtaaaaacg tttacaagta atgaaggaga
    37741 tgcaatgact gagaaagatt atggacaagt aacagggatg gtgcattcga cagaaagttt
    37801 tggttctgta gatggtccag gcattcgttt tatcattttc ttgcaaggct gtaaattacg
    37861 ttgccaatat tgccataatc cggatacttg ggagatggaa accaacaatt caaaaatcag
    37921 aacagtcaat gatgtcttga aagaagccct tcagtacaaa catttctggg gaaaaaaagg
    37981 aggaattacc gtatctggtg gtgaagctat gcttcaaatt gattttatca ctgccttatt
    38041 catcgaagct aaaaaattag gtatccatac cacactagac acctgtggct ttacctatag
    38101 accgacacct gaataccatc aggttcttga taacttattg gcagtgaccg atttgatttt
    38161 attggacttg aaagaaattg atgaaaaaca acataaaatt gtcacgcgtc agcctaataa
    38221 aaacatattg caatttgcta ggtatttatc cgacaagcag attcctgtct ggattcgaca
    38281 tgtcttggtt ccaggcttga ctgatattga tgatcatttg acacgattgg gtgagtttgt
    38341 caaaaccttg aaaaatgtcg ataaatttga agttttgcct taccatacca tgggagaatt
    38401 caagtggcgt gagctaggta ttccttatca gttagaaggt gttaaaccac caactaagga
    38461 acgcgttcaa aatgctaaaa atctgatgca gaccgaatct tacacagaat atatgaatcg
    38521 gattcatcag tcataagagc tgttataggg ttgaggtttc ctcaactttt taaagtatta
    38581 taagcagatc ttttgtaatc ttcctttgat tttagggggt aattttgcta aaataaaatg
    38641 aataaacaaa atgaggtaga atgattatgt caaaaatttt agtttttggt catcaaaatc
    38701 ctgatacgga tgctattgca tcatcttatg cttttgatta cttatcccaa aaagcgtttg
    38761 gtttggatac tgaagtcgta gctttaggaa cacctaacga agaaacagct tttgcccttg
    38821 attattttgg tgttgaggca ccacgtgtgg tagagtctgc taaagcacaa gggtctgaac
    38881 aagtgatttt gacagaccac aatgaattcc aacaatccat tgcagatatc cgtgaggttg
    38941 aggtatatgg tgtggttgat caccaccgtg tggctaattt tgaaactgca aatcctttat
    39001 acatgcgtgt ggaaccagta ggatcagcct cgtctattgt ttaccgtatg tttaaagaaa
    39061 atggcattga ggtgccaaaa gcgattgcag ggatgctctt atctggtttg atttcagata
    39121 ccttgttgtt gaaatctcca acaactcatg tgtctgatca ccttgtcgct gaagaattgg
    39181 cagagctagc agaagtgaac ttggaagact atggaatggc tcttttaaaa gcaggtacaa
    39241 accttgcaag caaatcagaa gtagaattga ttggtattga tgccaaaaca tttgaattaa
    39301 atggcaatgc tgtacgcgtg gcacaagtga acactgttga cattgcagaa gtcttagaac
    39361 gtcaagaagc tattgaagca gccattaaag atgccatggc tgcagaaggt tattcagact
    39421 ttgttttgat gatcacggat attgttaact caaactctga aattctagct attggagcaa
    39481 acatggacaa ggttgaagca gcctttaact tcacccttga caacaatcat gccttcttag
    39541 caggtgccgt ttctcgtaaa aaacaagtgg ttccacaatt gacagaaagt tttggagctt
    39601 aatgaaaaga cgctttaaaa ggacttggtt tttttgacca agtccttttt tcactcttct
    39661 atgctataat agaaggtatg ataacaatat ttcattcaga taaactcacc agacaacctt
    39721 tctttcaaga ccttatcaat tatctcgacc agcatgatca cgttatatta cgagagatca
    39781 aaaaagcctt tcctaatgtg acaggtattg acaaggccat cgaaagctat gttcaagctg
    39841 gctatattcg ccgtgaaaat aagcgttatg gcatcaacct tcctttggtg agttctgatc
    39901 agcagctggc cttagacact atgctttttg tggacacctg ttcagctatg tatgaaaata
    39961 ttttagcggt tgtttttgag actcagctaa caaaccaaac caatcacgtg atgatcaagg
    40021 aaaagaccaa catcacgaga agtcagttga ctctagctaa ttatttttac cgtctcaaaa
    40081 gaggtgagaa gccatcagct gagcagatag acttgtatga cctcttgggg gatgtgaatc
    40141 aggaatatgc ccttaaatat atgacaactt ttttgcttaa attcacgcgc aaagaccttg
    40201 tgatgcaaaa acgtcctgat atatttgtgg aagctctggt tacacttggt tacctaaaac
    40261 aagtggagcc tacaacatac cagctgctaa tgaccttgga taaagaaagt ttaaccttta
    40321 tagcaccata gaaaagagct aggaacaagg actgttctta gctttttgag tgcttttatt
    40381 ttgtttttgc cattaagtaa agaaaataag gggctccgat aagcgacact aaaatccctg
    40441 tctggatatt actgccaacc agatagactc gtcctactgt atctgcaaca agaagtagga
    40501 tcattccgat taaaatacta atgggtattg ttattttatg attactccct accaagtatg
    40561 tactaaagtg tccagctatt aagccgataa aactaatatt accaaccaaa agaacactca
    40621 aagcacctaa gccagctgct aagacaagta tcaaacgacg cttacggttt aaagggagtc
    40681 ctagtccaat agcagtatta tcagctaatc ccataatatt aaggaaatgg gcttgactat
    40741 aagtcaatag ccaaaaacac aataataaag gagcgatgac actcagagta ggccagtcgt
    40801 ctcctattaa ttggccgcta agccaattga tgaccaaatc gactttgtag cgattaatat
    40861 gaccaacaag agcaaccatt agacttgaaa gcatggtagt aacagctaca ccagtaagaa
    40921 ttaaccgtgt aggatcaatt tgtccttgtt ttgtcaaaga tagccaataa acgctaaagg
    40981 ttgttacaac agcaccaagc atggcaaata aaggcaagta atggctgata tgagcttgct
    41041 caaagaaaga aaaggagacc acaatagcca aagagatacc tgctcctata gtaataccta
    41101 atacaccaga gtcagctaag ggatttcgtg ttaaacgttg taataatagc cctgataaag
    41161 caagagaacc gcctcctaga caagcagcta gaattcttgg cagacgaatg ttaataacga
    41221 tgaaagatat ggcatggcta gattttccca aaaacacatg gacaaggtcc aaaaaagata
    41281 gatgagattc tccaagggac aaagctaatc ccataagact tacaagtagc aggatcaggc
    41341 tagtatataa ccttaaaagg tgtctttgag atttcaatag cggcctcctc ttcttattaa
    41401 ccataaaaag catggaaaac caattaagct aaccaatgcc ccaagagggg tttcataagg
    41461 cggattgaga ttacgacaag caatatcaac ccataccatg aaactagcgc cagaaactgc
    41521 acaaagcggc aaaaagtatc ggtaatgatg aggtgtaaag tgtttcataa gatgaggaat
    41581 gactaagccg ataaaagaaa tgcttccagc aatggctaca gctgctgatg ataaaataag
    41641 aaccaaaatc ataaagactg cactgatcaa gttggtcttt tgcccaagag cttttgcctg
    41701 agactcactt agactaagga cggtcaggtg ataagataat agctgggcta aacaaagact
    41761 aagaataata agaggagcaa tatagccgat catttgccaa ttgaccccga caagacctcc
    41821 tgcttgccag ccgataacag catttgtcag atgatagtaa ttggtaatac cttgacctaa
    41881 tgctgatagc agtatggaaa ccataactcc tgctaagaca aggcggagct gatggtagct
    41941 tttgccagat tgataagaaa ggccaaagac taaggttgct gccaggctag accctaacaa
    42001 cgaaagcaga ataatgaggg aatagtgcaa gtgaggtaca aacgcataag ccagtaccaa
    42061 ggctagtcct gctccagcat taatgcctaa aaggccaggc tcagcgatag gattacgtgt
    42121 gattgcttgc atgatagttc cagaaacagc taacgcagag ccagttaagg tagcaccaaa
    42181 aagtctcggt aatcgtatag cgagtaaaac attggcttta tggccgtttt gctttccaaa
    42241 taaaatagag ttaagatcct gatgtgataa agcaacggct ccaaagcgca gatgacagta
    42301 aatagcaaca cataagctaa aactaagtag cacaaagaca agccaaaaga tatgtgactt
    42361 agtgattatc tgcgtttttt ttaagcaaaa acgctcgaga cacaaaaagg gatgcttagt
    42421 tttcacttga taagattgcc tctcgtaaag tctctaattg atattctaaa gaaagaggat
    42481 cagtaaagta aaagacattg gcattgactt tgatcacatg gtgttttttc acagctggaa
    42541 tggattgcca tagcttgctt tcatatagag cagaaccagt cttatcatct tctgcagcaa
    42601 cgacgacata atcaccaata tagtctggca agacttcctg cgacaatgac aggtaacctt
    42661 gtttaaaaac ttcagtcttc actttttcag gagcatcata atggaaagct tgatggataa
    42721 cctctccgcc acgtccccag tctttaccaa aaaggtaaac gtctttttca taaagcccca
    42781 taatagtaaa ggttgctttg tcacctgtaa cggccttgac ttctttttca taagctgctg
    42841 ttttagtttt ccaatctttt aaccatttct tggctttgcc ttctttgtta aagatgcggc
    42901 cgaagtcaga taacacttgt aaataatcac gtttgcggta ttcaatcgaa ataacaggcg
    42961 caatttctgc caattgttta atattttctt ctgtagagcc aacaacaatg aggtcaggct
    43021 taagcgttgt aatggcttct aaatcagttg cagcaacttg ctttgctttt tttacagtct
    43081 ttgctaagat ggggtttttc ttgtcataag aagtaacccc gactagattc atatctaatt
    43141 ttttgaggta accagtgtaa gttgaagcca gactgactac tcgcttaggc tgtttaggaa
    43201 tatctccgta ataagtcaca ccagcaattt gaggcatagg cgataaactt tttgaggcgg
    43261 tgttagaatg attagttgct tgattaccac aggcgattaa ggtaatagtt gtcaaacaga
    43321 gtgttaatag tagagttaat tttttcatgt atgctaattc tcctagaata aagttattga
    43381 agctgataag tcagcactat aggacagttg tggataggat catcaaccag taccggtttg
    43441 atttggaaga tgtcttgaat gataggtgaa gtcataacat ctgctatagt accagtataa
    43501 tggatcttgc catgtttcat agcaatcaga tgatccgaat agcgggctga aagattgagg
    43561 tcgtgaagaa ccataacaat agtcttgccg gcatccttat ttagggattt aacgagctct
    43621 aggatttcta gttgatgatt taaatctaaa taagtagttg gctcatctaa aaaaatagta
    43681 tcagtgcctt gggctaatgc cattgcaagc caaacccttt gacgttgccc cccagaaaga
    43741 gcatcaacag gttgatcagc ataggccatg acattggtgg cttgtatagc ccaatgaatg
    43801 gcttttttgt cagctggact aagatttcca aagtaagatt gatggggaaa acgtccgtaa
    43861 gaaaccaatt cgtaaacagt tatgccgtta gttgcttctt gaacttgagg taaaagagct
    43921 agttttttag caacctcttt agtttctaat gtggcaatgt tttgcccatt taaatacaca
    43981 actccctgtt ttggtggtaa taatcttgtc agtgctttta ataaactaga cttcccacag
    44041 ccattggcgc caataatggt cgtaatttta ccttcaggaa tataaaacga taatttatcg
    44101 atgatggtac gctgttcata ggcaattgtg aggtcttcag cactaattgt tgtcatatgg
    44161 ttgcctcctt tctaaaaaga gtcaaagggt tgatgaaagt gcacattaaa gtgttcatct
    44221 gcccatttta aaatagttga gaagtagctt attttctcaa aatcttcact attatagcat
    44281 agaaaaaagg cttaacaaag ccttttttga tgtgattttt aggatgtatt aaaaaagaaa
    44341 tattagttta gaatgattaa aaacaatagc gataatcatt ctaaactaac gtcgacatac
    44401 tctagaggta gtgtttggcg attgctaaat caccagcata agctacttgt tgtcctttaa
    44461 caatttgata agcatctgcg cctttcccag cgataatcac agcatctttt gctccttggc
    44521 aaagagacat ggctttttga atagcttgct cacggtcact aataatctct accgggcgtg
    44581 cgatatggct ggcaatttct tttgaaatat cttctggatc ctcgaaatta gggtcatcag
    44641 cagtgagaat gacggtgagg tttggatgct gatgaatcac cctaccaaaa tcagctcgtc
    44701 tgctctcgcc tttatttcct ggtgcaccta aaatcaacat taatttgcct gtctgatgtt
    44761 cttccacaac gctgagtaat ttttctaagc tgtcaccatt atgggcataa tcaacaaaaa
    44821 ctttagcatg atttgtcata gtgaggactt ccatacggcc tgggacgcga gtcttagcga
    44881 tacctttttg aatatcagct aggctagcac ccaaacgaag gcaggcaagt ccagctgcca
    44941 tagcattttc ttggttaaaa tggccaatta attgaatgtc ataatggcca gctaattgtc
    45001 ctttagcttc aaaggagaaa gcttggctag tggtgatttg attgtcagac aagggaccat
    45061 aaaacacatg ctcttgatcc gctacctgat ccgctagaaa tgaaaaatga tccatcccgc
    45121 tattgatcac aacagctctg ctattctcca ttaaaagacg cttatgatag aaataatctt
    45181 caaacgttgg atgctcgatt gggccaatat gatcaggact aatatttagg aaaaccccaa
    45241 catcgaacgt aagcccatag acgcggccaa caagataagc ctgactggat acttccataa
    45301 tcaagtgggt catgccattt ttaacacact cggccatcat agcaaaaagg tctagacttt
    45361 caggagttgt caattgtgat ttgaagaaag tttgaccgtc caaggtagtg ttcatcgtag
    45421 acaacaaggc aggtttataa gattctttca aaatatggta ggcaaaataa gcagctgttg
    45481 ttttgccttt tgttccagta aaccctaaga gtttgagctg atcctgagga ttatcataga
    45541 aagccatagc gattaaactc atggcctttt taatatcagt gaccaaaaca acgggaatat
    45601 caagcttata atctacttct gagacataaa gaggaagtcc cttagcgatt gcttctttaa
    45661 ggtattcagc cttgaatgta gctcccttag caaaaaaaag ggtcttgcca tctacttgac
    45721 ggctatcgta actcaagcgc tcaaaactta agccttgata atggtagtgg tatccgtcgg
    45781 catcaagaac ctcacgaaaa ttatggtctt tttttaaaat gtctaataat tgttcaatgg
    45841 ttatcatacc cttattttat ccttaaagtt cttgttttac aagtcacaag caaaagttta
    45901 taataaagct aatagaaact aggaaagaat agatatgtcg acagaaaaaa aacaactgac
    45961 acaagaagaa ttgatggttc agggagcagc ctggtccaca gctggtaatt tcattagccg
    46021 acttttagga gtgttataca ttattccctg gtacatttgg atggggcaat acgcgattca
    46081 agccaatgct cttttcaata tggggtataa tgtttatgct tattttttat tgatttcaac
    46141 cacaggactt aatgttgcga ttgctaagca agtcgccaaa tacaattcta tggggcagac
    46201 ggagcatagc taccaattga ttcggagcac gttaaaactc atgcttggtt tgggtgttgt
    46261 gttttcggca attatgtatc taggttctcc cttatttacc agtttatctg gtggggatgc
    46321 taagcttatt ccaattatgc atagtctttc cttggctgtc cttgtctttc cagtcatgag
    46381 tgtcattcga ggcatttttc aggggcacaa taacattaag ccctatgcca ttagtcagat
    46441 tgctgagcaa ttgattcgag tcatttggat gcttctgacc accttcctta tcatgaaatt
    46501 aggttctggt gattacgctt cagcagtgac tcagtcaact tttgcagcct ttatcgggat
    46561 ggtggctagt atgggtgttc tgggttacta tctttggaaa cagggacttc taacagctat
    46621 ttttagtaag ccagatcata ccgtttctat tgatatcaag ggcttgttgc ttgaaacctt
    46681 aaaagaatcc atccccttta tcgtgacagg aagcgctatt caagcctttc agttgattga
    46741 ccagtggtcc tttgtgaata ccatgagtct gtttacagat tatagccgct ctcaattatt
    46801 ggttttattt ggttatttta acgctaatcc tgctaaaatt accatggttt taatcgctgt
    46861 agcagcttct atcggagggg ttggtattgc tttgttgaca gaaaattatg tcaaaaaaga
    46921 catgaaagca gctgctcgct taatcattaa caacattgaa atgttagtga tgtttttgtt
    46981 acccgctctt actggggcaa ttattttagc aagacctcta tattctgttt tttacggagc
    47041 tagcgaggat cgtgccattc acctctttgt ggcggtcctc ttccaaacct tgctactggc
    47101 gctttacacc ctcttttcac cgatgcttca agctcttttt gaaaatcgaa aagcgattta
    47161 ctactttgcc tatggtatct tgattaagtt agttttacag ataccgctta tttatttgct
    47221 acatgcttat ggtcctttac tagcgacgac gattgcttta gtggtgccga tttatttgat
    47281 gtatcgacgc ctatatcagg ttactcattt taaccgcaaa ctgttgcaaa aacgtttatt
    47341 attaaccttg attgaaacct tactaatggg actggtcgtg tttgtggcca actggctatt
    47401 gggctatgcc tttaaaccga caggccgctt gaccagcctt ctttacctcc tcattattgg
    47461 tggcttggga atgacggttt acacggcact caccttgctg acgcatcaac tggataaatt
    47521 aattggtagc aaagctagtc gccttcgtca gaaattaggc tggcattaat ataatgacac
    47581 caagaacgat ttcgtgagtg cttatcgaaa tcgttttttt cttaatgatc tcgcttagta
    47641 aaggtagctg ataaaaaatc aggatttccc aagcaaacta ctgatatttt tggtataatg
    47701 ataaaagtgt aaaaaaatag aaggaagtat atcaacatgg gaaaatgtca agttatttcg
    47761 catccgctta tccaacacaa actttcaatc ttacgtcgtc aaaccacatc aactaaagat
    47821 tttcgtgagt tggttaatga aattgcgatg ctgatgggat atgaagtgtc acgcgacctt
    47881 cccttagaag atgtcgacat ccaaacgcca gtctcaaaaa cggtccaaaa acagttagct
    47941 ggtaaaaaat tagctattgt tccgattctt cgtgctggta ttgggatggt tgatggcttg
    48001 ttaagtttgg taccagctgc aaaagttggc catatcggca tgtaccgtaa tgaagaaact
    48061 cttgaacctg ttgaatacct cgttaaacta ccagaagata ttaaccaacg acaaattttc
    48121 cttgttgatc caatgttggc aacaggtggt tcggctatct tagcagtgga ttcgttgaaa
    48181 aaacgtggtg cagcaaatat taagtttgtc tgtttagttg cagcaccaga aggggtgaaa
    48241 aaacttcaag aagttcatcc agatattgat atcttcacag cagcacttga tgatcattta
    48301 aatgaacatg gctatatcgt gccaggcttg ggcgatgctg gtgatcgttt atttgggaca
    48361 aaataaaaga gacaaccatc aaatagtagc ctttttaggc caatcgttct tgattttgtt
    48421 taaaaaatca gagagatttc tcttctttaa aggaaaagca agtttatgat ttgaccttta
    48481 ttgaccaaaa tattataata aagacaatca gtaaaaaaga gatgacctag tgggttgccg
    48541 tctctcaaaa tgacgctact aaaaaccctt gtagattgga gaatgtatta tgattcctgt
    48601 tgttattgaa caaactagcc gtggagaacg ttcttatgac atttattcac gtttattaaa
    48661 agaccgtatt atcatgttaa cagggcctgt cgaagacaac atggccaact ctgtcatagc
    48721 gcagctctta ttccttgacg cgcaagacaa cacgaaagat atctacctat atgtcaacac
    48781 accaggtggc tctgtctcag caggcttggc tattgtcgat accatgaact ttatcaaggc
    48841 cgatgtgcaa actattgtca tgggtatggc agcttctatg gggacagtca ttgcttcatc
    48901 aggaacaaaa ggcaaacgct ttatgttacc aaatgcagag tatatgatcc accagccaat
    48961 gggtggcaca ggcggtggca cgcaacaaac ggatatggct atcgcagcag aacatctctt
    49021 aaaaacacgt caccgtttag aaaaaatctt agcgcaaaat gctggaaaaa cgattaaaca
    49081 aatccataaa gatgctgagc gtgattattg gatgagtgct gaagaaacct tggcttacgg
    49141 tttcattgat gaaatcatgg aaaacaacga actaaaataa agaggatctc tgcaaaagta
    49201 ttctagaaac ttctaggatg ctttttctct tagaaaggaa aataatgata cagcctactg
    49261 cattaaaaca gcttcaagag ttaaaacgtc agttcagatc cctttgcaac caattatgag
    49321 atagtttgag gatgatcctt agcagctgtg tgcaagaagt tatgacgatt tcataaagga
    49381 tgacctagcc agtctttctt cgtctctttt acttaaagtg tggtataatc agattatgct
    49441 agccaaaact aaaaaatgca ttgccattaa aggtgttgta gatcggctta tcctagatct
    49501 cataacaatg ctgtagtacc gcccttacct tgctactaaa ggcgctgttg aagcacaaat
    49561 tgacttgcaa aggatcttga ctgataggta tatgtccggt ggaatcgcta aagcagcaaa
    49621 aagaccaaga cccttctttg gtctctacca aaatataata gaaaaggatt tagaatgttt
    49681 caaaaacaag aacgtattgg actcgtcgtt tacctgtatt ataaccgaga tgccagaaag
    49741 ttatcaaaat ttggtgattt atattaccat tccaagcgct ctcgttacct cattatttat
    49801 attaataaaa atgatttaga cacaaaatta gaagaaatga gacgtttgaa atgtgttaaa
    49861 gacattagac catcagcttt tgatgatatt gaccgccaat ttgtaggtaa ccttcatcgc
    49921 gacgaaacaa acaaccatca aaagggttaa caccccccta gttactgatt agcgtttcag
    49981 atttagttag cttattaaag taagaaggtt ttgacagatg ctcacactac ttcaagacaa
    50041 tgagacaact agagcattag tgaataactg agttgactgt cacttcttta ataagaacgg
    50101 ataggattgg tcctaaaata gagcactgca aagatatgcc agtgcttttt agctcatttt
    50161 ttgataaaat agaactacta aaaagtgaag gaaataagat gatcacagga aaactcataa
    50221 ccgttgaagg tccagatggc gcagggaaaa cgactgtttt agagcaactc attccactgt
    50281 taaaacaaaa agtggctcag gagatcttga caacaagaga gcctggaggt gttgccattt
    50341 cagaatacat tagagaactt attttagaca tcaaccatac tactatggac cctaaaacag
    50401 agctcttact ttatattgcg gctcgaaggc agcatttggt ggaaaaggta ctaccagctc
    50461 ttgaagcagg ccagttggtt tttattgatc gtttcatcga tagttcagta gcttatcaag
    50521 gtgcgggacg cggtttgacc aaagcagaca ttcagtggct caacgagttc gcaacagatg
    50581 gtttagagcc tgacttgacc ctttattttg atgttccttc tgaaattggt ttagcacgga
    50641 ttaacgcgaa ccaacaaaga gaagtcaatc gtttagattt ggaaacaata gagatacatc
    50701 aacgagtacg aaaaggatac ctagccttag ctaaggagca tccaaaacgt attgtcacaa
    50761 ttgatgcgac taaaccattg aaagaagttg tctctgtcgc tttggaacat gtcttagcct
    50821 tgcttttagc ctaggataag ggagggtagg aatggattta gcgcaaaaag ctcctaacgt
    50881 ttatcaagct tttcagacga ttttaaagaa agaccgtctg aatcatgctt atcttttttc
    50941 gggtgatttt gctaatgaag aaatggctct ttttttagct aaggtcatct tttgtgaaca
    51001 gaaaaaggat cagacgccct gcgggcattg tcgctcttgt caattgattg aacaaggaga
    51061 ttttgccgat gtgacggtat tggaaccaac agggcaagtg attaaaacgg atgtggtcaa
    51121 agaaatgatg gctaactttt ctcagacagg atatgaaaac aaacgacaag tttttattat
    51181 caaagattgt gacaaaatgc ataccaatgc cgctaatagc ttgctaaagt atattgagga
    51241 gcctcaggga gaagcttaca tgtttttgct gaccaatgat gataacaaag tgcttccgac
    51301 cattaaaagt cggacacagg tttttcagtt tcctaaaaac gaagcctatc tttaccaatt
    51361 ggcacaagaa aagggattat taaaccatca ggctaagcta gtagccaaac ttgccacaaa
    51421 caccagtcat ctagaacgtc tgttgcaaac gagcaagctt ttagaactga taactcaagc
    51481 agagcgtttt gtatctattt ggctgaaaga tcagttgcag gcatatttag cgttgaaccg
    51541 tctggtacag ttagcaactg aaaaagaaga acaagattta gttttgaccc ttttgacctt
    51601 gctcttggca agagagcgtg cgcaaacgcc tttgacacaa ttggaggctg tttatcaggc
    51661 taggctcatg tggcagagca atgttaattt tcaaaacaca ttagaatata tggtgatgtc
    51721 agaataagtg caattggaat tcgttatggg gaaacgaagc ttgtcaaaag acttgccctt
    51781 agcgaccaaa gtagcggcgc ataggggcaa aacaagcttt tgaagaaaat actgcctttg
    51841 caacagattt gatgaaagaa gtatcacgat taataacaca aaatcaactt gaaatgacgt
    51901 ttattaatag tgtctttccc ttagatcagc atgttgtcct aattcccttt tcagcagaag
    51961 agcacatgga tttttacaac tgttaaaaga tttagcggcc gattttaggt caagaagtga
    52021 gctgccccag attaacagcc aagaagaaac caagatttat gggcgcttag gaccgtgtgg
    52081 cagaccactg tgctgctttc gtttttggga aaatttctga cagtatctat taaaatacta
    52141 aaaaatcaaa ggttatcatt gactttgggt aaagcaacaa gcccttatgg ccgtttgctt
    52201 tgctgtctct atgatgaagg tggcttttac caataaagca agaaaaaatt ccctgaatat
    52261 ggtaccatag tagagacaag tgatggccct gcaacagtag cagccttgat atatttacag
    52321 atcccattaa ggtgcggtta aaagaccagt tgaccttagt cacttatgct ttagaggagg
    52381 ttaaagtagg tgaataaaaa agaattattc gatgcttttg atggattttc ccaaaattta
    52441 atggttactt tagctgaaat tgaagccatg aaaaaacaag tccaatcact agtagaagaa
    52501 aacacgattc ttcgcctaga aaatacaaaa ctacgggaac gtttgagtca cctagaacat
    52561 gaaacggtag ctaaaaatcc ttccaaacaa aggaaggatc acttagaggg aatttatgat
    52621 gaagggtttc atatctgcaa ttttttctat ggacaacgtc gtgaaaatga tgaagaatgt
    52681 atgttttgca gagaattatt agatagaaag taagggcatg caggttcaaa aaagttttaa
    52741 agacaaaaaa acaagcggaa ccttgtattt ggttccaacc ccgattggca atctgcagga
    52801 catgaccttt agagcagtgg caacgttaaa agaggttgat tttatttgtg cagaagacac
    52861 aagaaacaca ggtcttttgc taaaacactt tgacattgct accaagcaaa tcagctttca
    52921 tgagcacaac gcctatgaga agattcctga tttaattgat ttattaatat caggacggtc
    52981 attagctcag gtgtctgatg caggaatgcc atcgatttct gatcctgggc atgatttggt
    53041 caaggctgct attgatagtg atatcgcagt cgttgcttta ccaggtgcct cagctgggat
    53101 tacagctttg attgctagtg gactggctcc tcaaccccat gttttttatg ggtttttacc
    53161 cagaaaagca gggcaacaaa aggctttctt tgaggacaaa caccattacc cagagacaca
    53221 aatgttttat gaatcaccct atcgcatcaa agataccctg accaatatgt tggcttgtta
    53281 tggtgatcgt caagtggtgc ttgtcagaga attaaccaag ctttttgagg agtaccaacg
    53341 gggggcgatt tcagaaatct tgtcctacct tgaggaaaca cccctaaaag gggagtgtct
    53401 gctgattgtg gctggagccc aagtagacag tgaggttgag ctgacagctg atgttgactt
    53461 agtgtctcta gtgcaaaaag aaatccaagc aggagccaag ccaaatcagg ctattaaaac
    53521 aattgctaaa gcttaccagg taaatcgcca agagctttac caacaatttc atgacttata
    53581 agtcatcgta gattaggaga aaaacaaatg acagaagatc aagcaactat ccttatttta
    53641 ggagtatacg gaatcatatt ggctgtattc ttattatcag ctttattatg ccttatcgct
    53701 aactggcgac tctttaaaag agcaggttac aaaggatggt atagtctcat tcctttctat
    53761 gcaggttttg tcaaacacaa aatcactttt ggagaagata ataaatggtt ttactttatt
    53821 ggttgggtca ttgctattta ttattactat gtgcactttt gctatgtccg tgcttttggt
    53881 ggatcaaagg gtctagcagt atttggcttg tttttcccag gcattgcttc tttgatagtg
    53941 gcttttggaa aaacttatac cacacaagaa tgccaccctg tgccacatct tttaaactaa
    54001 gagagaaaag actatcaatt ggatttattg atggtctttt aggtgtttaa atgattttag
    54061 tcccgtgaac aatggccgtt ccagtgagtt gactcaagct ttggcaattc tcagcagtga
    54121 cgcctcctcc aatcatgatt tcaatgcgtt tattggcata ggtcacaaga cttttaagtt
    54181 gttccacatt gtctgtaata ggagtagctt caggggagcc atgagttagc acacgcacaa
    54241 agccataatc aatcagttga tcaagcgctt ggtgctggtg atcagtcgga atatggtcaa
    54301 aagccatgtg gaaaaccagt ggcaagcctt gtgtagcagg cagtaattgc tcgatagcgt
    54361 cggtatccag ttgattttct gtggtcagca agcctaagac tagcgcatct gagccagctt
    54421 caacagcttt taagatatct tcttccatag cttttagttc gaggtcgtta tagacaaaat
    54481 cgccaccgcg aggtcgaatc atggtcgcta cgctaatctt tttatcgtgt aagagctgac
    54541 aggcttcttt gatgacgcca taagatggcg tggtccctcc gacagctagg ttatcacaga
    54601 gttccacacg actgacttga ccagcatcaa gggttggcag tagtgtgagg ttctcagcac
    54661 aaaattcttt aatcattttt agttctcctt tatcactaat attatagcac gaatgaagct
    54721 agtcatcagg aaacattttt gtcaaatcat ggacattatg ctatactcac tagtattaaa
    54781 agtaggccaa aacagcagca aatactttga aaaaagcttg ctatgttcta cggcaatatc
    54841 agtctttacc aacgaactct caagaagaaa agaaagacaa agcttagcat tttaaaaaag
    54901 cctccccttt ttttgtgaaa tgatgaccaa aaacaggcgc ctcacgccta aaacagttac
    54961 cctaaaggag aaaaaatgat tacgatttac caatacccaa aatgtagcac ctgccaaaga
    55021 gccatggctg aattaaagca actggttagt gactttgaag ccattgacat caaagctaat
    55081 ccacccaaag ctcaggacct caaacattgg atggaaacat ctggttatac catcaaaaat
    55141 ttctttaata ccagtggtaa cagctaccgc gaattgggac ttaaagataa aatagaccag
    55201 cttagccttg ataaagctgc tgaactctta gccacagatg gtatgctgat taaacggcct
    55261 attctgatta aggacggtaa agtcctacaa gttggctatc gcaagccata tcaagagttg
    55321 gatttaggat aatgcgacaa agtctcaaaa aaggacaagg caacattata acgccttgtc
    55381 cttttttggg atctgttttt agacattaga gatcaatatc tagtaaaatt ggtgtatggt
    55441 cttggcgttc cccagaagaa atcatttcag aacgcttaac cttatccacg attcggtttg
    55501 aagctaggca atagtcaatt ctccaaccgg tattattgat tttgctggtt ttgctacgtt
    55561 gtgcccacca ggtataaaca tgaggaatat cgccgtgcaa gtgacgaaaa gtatctgtaa
    55621 agcctcttgc taataggtta gtaaagcctt gacgttcttc gtcggtaaaa ccaggggaac
    55681 gtcgattgct gcttggattt gccaaatcaa tctctttgtg ggcaacgttg taatctcccg
    55741 tagccaaaac aggcttttga gtatcaagtt cagtcaagta atcagcgtat ttgtggtccc
    55801 agatttgacg gtcatctaac cgtcttagac catcaccagc attaggcgtg taaacctgtg
    55861 tgacgaaaaa gtcttcaaat tctagggtaa tgatacggcc ctcagcatcc attgttgttg
    55921 gggcaccaat ttctggaaaa gtaatgacag ggtttaacgt gtttttgtac aggaacatgg
    55981 tgccagcata gcctttccta gcaggctcaa ctgaagaacg ccacacatgc aaatagtttg
    56041 gaaagtaact aagtagggtc tcaatatgtt ttttggtagg ccccttagca gataatttgg
    56101 tttcttgaat ggcaataata tccgcatctt gagcgactaa agtgtctaaa acagcgcgtg
    56161 ataaaagcgc acgaggggac tctcctgtga gagcagcatt taaggaatca atgttccatg
    56221 aaatcagttt catttggttt ctctttctaa cagatagtct tgttgttatt gtaacaaaaa
    56281 acgaaacgat aagcgacttt gggcacctag cccccataaa acagtctagc caaatgaagc
    56341 atagcagcgt aagaacaaga caaggaggtg atcagtgagc atatcgtttg acagttaaga
    56401 gtaggattac tataatagaa acacaaatgt aagcgctaac aaaataaaaa atataggaga
    56461 atgtcaatgg cacaaaaaac agtcatcacc gaagaaacaa ccgattttgt tatggatttc
    56521 aaaacaagta gcgctgaggg aaatgttgat tttattaacg tttttgacct tgagaaaatg
    56581 gcacaacagg tcatccctaa aggagccttt ggttatattg ctagtggtgc tggtgatacc
    56641 tttaccctcc atgaaaatat tcgctcattt aatcataaat taattgtccc tcactccctc
    56701 aaaggggttg aaaatccgtc aacagagatt acgtttgatg gtgattactt aacctctcct
    56761 cttattttag cacctgtagc ggctcataaa ctggccaatg aacaaggaga agtagcgtct
    56821 gctaaaggat tgaaggaatt tggaagtatc tacaccacta gttcctactc aacaactgac
    56881 ctgccagaaa tcagtgctgc cttaggtggg acaccccatt ggtttcaatt ttattacagt
    56941 aaagacgatg gcattaatcg taatattatg gatcgtgtca aagcacaagg ttgcaaagct
    57001 atcgttttga cagcagatgc aacagttgga ggaaaccgcg aagttgatag gcgaaacggt
    57061 tttgtttttc cggtcggtat gccaattgtt caagaatatt tacctgatgg tgcaggtaaa
    57121 acaatggatt atgtctataa atcagctaaa caagcgctta cctcaaaaga tattgaatat
    57181 atcgcaactt actcaggcct gcctgtttat gtcaaaggac cacagtgtgc tgaggatacc
    57241 ttgcgggcat tggacgcagg agcatcaggt atctgggtaa ccaatcatgg tggccgtcaa
    57301 ttagatggtg gtccagctgc ttttgattcc ttacaagaag tcgctgaagc agttaatcaa
    57361 aaagttccta ttgtctttga ctcaggtata agacgaggtc aacatatttt caaagctctt
    57421 gcttcaggtg ctgaccttgt tgccttgggg cgtccagcga tttacggctt ggctatggga
    57481 ggaagcattg gtactcgtca ggtctttgaa aagttaaatg acgagttaaa aatggtcatg
    57541 caactggctg ggacacaaac tatccaagat gttaaagcct ttaaccttcg ccacaatccg
    57601 tatgattcat cgattccatt tgatcaaaat gcgttacgct tagattagaa cagacaaaaa
    57661 cctccgctat catgtcacaa atagtagagg ttttacactg caaaaagagg tatgaaaatc
    57721 caataacata gttacaaggc tttcgcttac caacccctac taatagatta aaatgaaaga
    57781 cttcttacat taatagaaat ttctgttgct tttctcagaa aaatgtggtt aaataatcaa
    57841 atattattaa cgaaaaatga gttaatgatt aacattaaac tggttttagt taaaacattt
    57901 aggagggtat caggtggaga aaaagcaacg tttttccctt agaaaataca aatcaggaac
    57961 gttttcggtc ttagtaggaa gcgttttctt gatgatgaca acaacagtag cagcagatga
    58021 gctaaccaca acgagtgaac caacaatcac gaatcacgct caacaacaag cgcaacctct
    58081 caccaataca gagttgagct cagctgaatc acaatcccca gacacatcac aagtaactcc
    58141 agagacaaat cgtgaaaaag agcaatcaca agatctagtc tctaagccaa ccacaactga
    58201 gctagctgac acagatgcag caccaatggc taatacaggt cctgatgcga ctcaaaaaag
    58261 cgcttcttta ccgccagtca atacagatgt tcacgattgg gtaaaaacca aaggagcttg
    58321 ggacaaggga tacaaaggac aaggcaaggt tgtcgcagtt attgacacag ggatcgatcc
    58381 ggcccatcaa agcatgcgca tcagtgatgt atcaactgct aaagtaaaat caaaagaaga
    58441 catgctagca cgccaaaaag ccgccggtat taattatggg agttggataa atgataaagt
    58501 tgtttttgca cataattatg tggaaaatag cgataatatc aaagaaaatc aattcgggga
    58561 ttttgatgag gactgggaaa actttgagtt tgatgcagat gcagagccaa aagccatcaa
    58621 aaaacacaag atctatcgtc cccaatcaac ccaggcaccg aaagaaactg ttatcaaaac
    58681 agaagaaaca gatggttcac atgatattga ctggacacaa acagacgatg agaccaaata
    58741 cgagtcacac ggtatgcatg tgacaggtat tgtagccggt aatagcaaag aagccgctgc
    58801 tactggagaa cgctttttag gaattgcacc agaggcccaa gtcatgttca tgcgtgtttt
    58861 tgccaacgac gtcatgggat cagctgaatc actctttatc aaagctatcg aagatgccgt
    58921 ggccttagga gcagatgtga tcaacctgag tcttggaacc gctaatgggg cacagcttag
    58981 tggcagcaag cctctaatgg aagcaattga aaaagctaaa aaagccggtg tatcagttgt
    59041 tgtagcagca ggaaatgagc gcgtctatgg atctgaccat gatgatccat tggcaacaaa
    59101 tccagactat ggtttggtcg gttctccctc aacaggtcga acaccaacat cagtggcagc
    59161 tataaacagt aagtgggtga ttcaacgtct aatgacggtc aaagaattgg aaaaccgtgc
    59221 cgatttaaac catggtaaag ccatctattc agagtctgtc gactttaaag acataaaaga
    59281 tagcctaggt tatgataaat cgcatcaatt tgcttatgtc aaagagtcaa ctgatgcggg
    59341 ttataacgca caagacgtta aaggtaaaat tgctttaatt gaacgtgatc ccaataaaac
    59401 ctatgacgaa atgattgctt tggctaagaa acatggagcc ctgggagtac ttatttttaa
    59461 taacaagcct ggtcaatcaa accgctcaat gcgtctaaca gctaatggga tggggatacc
    59521 atctgctttc atatcgcacg aatttggtaa ggccatgtcc caattaaatg gcaatggtac
    59581 aggaagttta gagtttgaca gtgtggtctc aaaagcaccg agtcaaaaag gcaatgaaat
    59641 gaatcatttt tcaaattggg gcctaacttc tgatggctat ttaaaacctg acattactgc
    59701 accaggtggc gatatctact ctacctataa cgataaccac tatggtagcc aaacaggaac
    59761 aagtatggcc tctcctcaga ttgctggcgc cagccttttg gtcaaacaat acctagaaaa
    59821 gactcagcca aacttgccaa aagaaaaaat tgctgatatc gttaagaacc tattgatgag
    59881 caatgctcaa attcatgtta atccagagac aaaaacgacc acctcaccgc gtcagcaagg
    59941 ggcaggatta cttaatattg acggagctgt cactagcgga ctttatgtga caggaaaaga
    60001 caactatggc agtatatcat taggcaacat cacagatacg atgacgtttg atgtgactgt
    60061 tcacaaccta agcaataaag acaaaacatt acgttatgac acagaattgc taacagatca
    60121 tgtagaccca caaaagggcc gcttcacttt gacttctcgc tccttaaaaa cgtaccaagg
    60181 aggagaagtt acagtcccag ctaatggaaa agtgactgta agggttacca tggatgtctc
    60241 acagttcaca aaagagctaa caaaacagat gccaaatggt tactatctag aaggttttgt
    60301 ccgctttaga gatagtcaag atgaccaact aaatagagta aacattcctt ttgttggttt
    60361 taaaggacaa tttgaaaact tagcagttgc agaagagtcc atttacaggt taaaatctca
    60421 aggcaaaacc ggtttttact ttgatgaatc aggtccaaaa gacgatatct atgtcggtaa
    60481 acactttaca ggactcgtca ctcttggttc agagaccaat gtgtcaacca aaacgatttc
    60541 tgacaatggt ctacacacac ttggtacctt taaaaatgca gatggcaaat ttatcttaga
    60601 aaaaaatgcc caaggaaacc ctgtcttagc catttctcca aatggtgata acaaccaaga
    60661 ttttgcagcc ttcaaaggtg ttttcttgag aaaatatcaa ggcttaaaag caagtgtcta
    60721 ccatgctagt gacaaggaac acaaaaatcc actatgggtc agcccagaaa gctttaaagg
    60781 agataaaaac tttaatagtg acattagatt tgcaaaatcg acgaccctgt taggcacagc
    60841 gttttctgga aaatcgttaa caggagctga attaccagat gggtattatc attatgtggt
    60901 gtcttattac ccagatgtgg tcggtgccaa acgtcaagaa atgacatttg acatgatttt
    60961 agaccgacaa aaaccggtac tatcacaagc aacatttgat cctgaaacaa accgattcaa
    61021 accagaaccc ctaaaagacc gtggattagc tggtgttcgt aaagacagtg tcttttatct
    61081 agaaagaaaa gacaacaagc cttatacagt tacgataaac gatagctaca aatatgtctc
    61141 agtagcagac aataaaacat ttgtggagcg acaagctgat ggcagcttta tcttgccgct
    61201 tgataaagca aaattagggg atttctatta catggtcgag gattttgcag ggaacgtggc
    61261 catcgctaag ttaggagatc acctaccaca aacattaggt aaaacaccaa ttaaacttaa
    61321 gcttacagac ggtaattatc agaccaaaga aacgcttaaa gataatcttg aaatgacaca
    61381 gtctgacaca ggcctagtca caaatcaagc ccagctagca gtggtgcacc gcaatcagcc
    61441 gcaaagccag ctaacaaaga tgaatcagga tttctttatc tcaccaaacg aagatgggaa
    61501 taaagacttc gtggccttta aaggcttgaa aaataacgtg tataatgact taacggttaa
    61561 cgtatacgct aaagatgacc accaaaaaca aacccctatc tggtctagtc aagcaggcgc
    61621 tagtgcatcc gctattgaaa gtacagcttg gtatggcata acagcccgag gaagcaaggt
    61681 gatgccaggt gattatcagt atgttgtgac ctatcgtgac gaacatggta aagaacatca
    61741 aaagcagtac accatatctg tgaatgacaa aaaaccaatg atcactcagg gacgttttga
    61801 taccattaat ggcgttgacc actttactcc tgacaagaca aaagcccttg gctcatcagg
    61861 cattgtccgc gaagaagtct tttacttggc caagaaaaat ggccgtaaat ttgatgtgac
    61921 agaaggtaaa gatggtatca cagttagtga caataaggtg tatatcccta aaaatccaga
    61981 tggttcttac accatttcaa aaagagatgg tgtcacactg tcagattatt actaccttgt
    62041 cgaagataga gctggtaatg tgtcttttgc taccttgcgt gacctaaaag cggtcggaaa
    62101 agacaaagca gtagtcaact ttggattaga cttaccggtc cctgaagaca aacaaatagt
    62161 gaactttacc taccttgtgc gggatgcaga tggtaaaccg attgaaaacc tagagtatta
    62221 taataactca ggtaacagtc ttatcttgcc atatggcaaa tacacggtcg aattgttgac
    62281 ctatgacacc aatgcagcca aactagagtc agataaaatc gtttccttta ccttatcagc
    62341 tgataataac ttccaacaag ttacctttaa gatgacgatg ttagcaactt ctcaaataac
    62401 tgcccacttt gatcatcttt tgccagaagg cagtcgcgtt agccttaaaa cagctcaagg
    62461 tcagctgatc ccgcttggac agtccttgta tgtgcctaaa gcttatggca aaaccgttca
    62521 agaaggtact tacgaagttg ttgtcagcct gcctaaaggc taccgtatcg aaggcaacac
    62581 aaaggtgaat gccctaccaa atgaagtgca cgaactatca ttacgccttg tcaaagtagg
    62641 agatgcctca gattcaactg gtgatcataa ggttatgtca aaaaataatt cacaggcttt
    62701 gacagcctct gccacaccaa ccaagacaac gacctcagca acagcaaaag ccctaccatc
    62761 agcgggtgaa aaaatgggtc tcaagttgcg catagtaggt cttgtgttac tcggacttac
    62821 ttgcgtcttt agccgaaaaa aatcaaccaa agattgataa caaagcgcaa agagacaaca
    62881 aatcatccct tttaacagtc tgacctttct ttgagattga gctggcagat gatcatttct
    62941 taacaaaagt taaagagttg agcaaagtaa ggaacagaca taaagaccat aaaagcaagc
    63001 cagtttggct tgcttttatg gtgttattgt cgtgtgctac gatgactgaa aaagagcaac
    63061 gaacaatgac ctcgaatcac caaaaggact tgatttgata gcttccctat gctatactaa
    63121 gcctattctt tcaagaagga ctccttttgt ggaaaagact gaaaaaaagg acactaatct
    63181 atccaaaaac tccagatgag tagctgcatg agtagctgca accggatgcc tctgctgtga
    63241 tcaaggtggt aaagcagact ggcttgtcac tacctgagca ggtgtcaaaa aaagaagctt
    63301 tggctttgtc attcaacata ctgagcttta gtctttcaga acggagacac ccccagtttt
    63361 gtactcaaaa agcataaaca gctctgctga tgcgacatcc gatttctacg tccgcagtga
    63421 gccaaaccag ctgctgtttg ctatggtaaa agtggcgcca atcgggattt ttgagatcct
    63481 aggctcaaaa ataaggcata gaattccaaa ggaagtcgct gccgtgagca caacctaaga
    63541 aaaactattc caaaagactt tttctgcaat ttgaaatact gaatttcagt attttttctt
    63601 ttgtaactaa gagcaatgaa tgaggtaaaa aaaggcaaca atgtcaaaaa agaaacgaaa
    63661 acactatcag gtttatgagg gattacgctg tgctatgacg ctttgtttta tcagtggcta
    63721 tgtcaatgcc tttacctata tgacacaagg caaacgtttt gcaggtgttc agacaggcaa
    63781 ccttttgtca tttgccattc gcttgtcaga acagcaactg aaggaggcac tgcaattttt
    63841 acttcccatg atagttttta tgcttgggca gtcctttact tatttcatgc accgctgggc
    63901 cactaaaaaa gggctccact ggtacttatt atcaagcttt atcttaacag ggattgcttt
    63961 tggaacggcc ctattcacgc cttttcttcc ttccaatgtt acggtagcag ctttagcctt
    64021 ttttgcctct attcaagttg atacgtttaa aaccttacga ggagctagct atgctaatgt
    64081 gatgatgaca ggaaatatca aaaatgccgc ctatttacta accaaaggct tgtacgaaaa
    64141 aaatcacgaa ctaacacata tcggacgcaa caccttaata gtcattttgg cttttgctgt
    64201 tggggtggtt tgttcgacgt tgctttgcat agcttatggc gagtatgctt tgatacctat
    64261 tttaatgcct ttactctatg tcaattacct gttggctcag gaattttatc acattcaaac
    64321 caaaatcaaa ccgattaaaa gaacttaacg gacttgtgga gaaagaaagt tcatttaggg
    64381 taagttttta ctgaccctcc gttgatttgc tggttttgct gccccttaaa atatgatata
    64441 atagaccatt gatagctgtt acttaacaga aggctgataa aaaaggttcc attagccttg
    64501 agggttgaat ttaaacaggc aaaaacgaaa tcctacacta tgcatctcaa tcatactttc
    64561 atttgagtat ggttctgaaa ggaaactatg atgaaaaaac cattttacat tacgacaccc
    64621 atttattacc catctgggaa attacacatt ggttctgcct atacaactat tgcttgtgat
    64681 gtcttggcac gctacaagcg cctgatgggc catgaggtct tttacctcac aggactagat
    64741 gaacacggac aaaagattca aaccaaggca aaagaagctg gtattacacc tcaaacctac
    64801 gttgataaca tggcaaagga tgtcaaagcc ctttggcaat tgctagatat ttcctatgac
    64861 acatttatcc ggacaactga cgattaccac gaagaagtcg ttgctgctgt ttttgaaaaa
    64921 ttgctggcgc aagacgacat ttaccttggc gaatactctg gttggtattc tgtctctgat
    64981 gaggaatttt tcactgaaag ccaattaaaa gaagtcttta gagatgaaga cggtcaggtt
    65041 attggaggga ttgccccatc aggtcatgag gtcgagtggg tctctgaaga atcctatttc
    65101 ctacgcctta gcaaatacgc tgattgtctt gtggccttct ttaaagagcg acctgacttt
    65161 atccaaccag atggtcgtat gaatgaaatg gtgaaaaact ttatcgagcc aggtctagaa
    65221 gatttggctg ttagccgtac tacctttaca tggggtgtac ctgttccatc agacccaaaa
    65281 cacgtggttt atgtgtggat tgatgccctc ttaaattacg cgacagctct tggttatggt
    65341 caagctaatc acgctaactt tgataaattc tggaatggaa cggttttcca catggttgga
    65401 aaagatatct tacgttttca tagcatctac tggccgatct tactcatgat gcttgattta
    65461 ccaatgccag accgcttaat tgctcatggt tggtttgtta tgaaagacgg taaaatgtct
    65521 aaatcaaaag gcaatgtggt ctatccagaa atgttagtgg agcgctttgg acttgatcct
    65581 cttcgttatt acctcatgcg ttctttgcca gtgggttcag acgggacctt tactcctgaa
    65641 gattatgtgg gtcgtatcaa ctatgagtta gccaacgacc ttggtaattt attgaatcgt
    65701 accgttgcga tgatcaacaa gtattttgat ggcacggtgc cagcttacgt tgacaacgga
    65761 actgcctttg atgctgactt aagtcaactg attgatgctc agctagcaga ctatcataag
    65821 tacatggaag cggtggatta cccacgcgcc ttggaggctg tttggaccat catcgctcgt
    65881 accaacaaat acatcgatga aaccgctcct tgggtgctcg ctaaagaaga tggtgacaaa
    65941 gctcaactag ccagtgtcat ggcacacttg gcagctagct tgcgcgtggt cgctcatgtg
    66001 atccaaccct ttatgatgga aacatcagct gctatcatgg cccagcttgg cttagcgcct
    66061 gtttctgact tgtcaacact tgctctagca gcttttcctg ccaatacaaa ggtcgttgcc
    66121 aaaggcacac cgattttccc acgtcttgac atggaagctg agattgacta catcaaagct
    66181 caaatgggtg acagctcagc tatttcccaa gaaaaagaat gggtccctga agaggttgcg
    66241 ctcaaatctg aaaaagacgt catcacattt gaaacctttg atgctgtgga aatccgggtg
    66301 gcagaagtca aggaagtgtc aaaagtggaa ggttcagaaa aattgctgcg ctttagagta
    66361 gatgcaggag acgggcaaga ccgtcaaatc ttgtcaggta ttgccaaatt ttaccccaac
    66421 gaacaagaat tagtgggcaa aaaactacaa attgttgcta accttaaacc tcgtaaaatg
    66481 atgaaaaaat acatcagcca aggcatgatt ttatcagcag agcatggaga tcagctaacg
    66541 gtcttaaccg ttgattcctc tgttccaaat ggaagtatca ttggttgatg ctgacctatt
    66601 attcaaaaaa cctaagcaag aatatgtgct taggtttttt tgattgcctt taagaaagac
    66661 gaataacgag atgggtgata tggcatcaaa agcataacta tcctaggacc tgtcctagta
    66721 agattgctgt gcttttgaca agtgaacaga gaggtcttaa actatatctt gtcataaaaa
    66781 agattgcaaa acactatatc ttgtgttatt atggttttta taaaagttaa gcatgcttaa
    66841 ctttagccaa acaaaagagg acactagagc gtgtcccaca agacagttga gcccttcgct
    66901 tttttagtag agtaggagtg ctcaagtcaa aaagagacat cccatcaaac cattgctgtt
    66961 tagcaggtct ttttgtgttg ctcaaaaaga caattcctgt ctgtttggcg tctagtgatg
    67021 acttaggctt agcgctacta gacttttgtt tgaaaaatac ctcaagcctt gaaggagaca
    67081 aatgacccaa cattattatg aacgttcgca atccccaatt gaatacgccc tatctgaaac
    67141 acaaaaacag ttgcgctcca tcaattggaa ttaccttaat gatgacaaag atttggaagt
    67201 gtggaaccgt gtcactcaaa atttttggtt gcctgaaaag gttcctgttt ctaatgattt
    67261 aaattcttgg cgctccttgg gtgaggattg gcaacagctc atcacaagga cctacactgg
    67321 gttgacttta ctagatacag tacaagcaac ggttggtgat gtggcacaaa ttcagcattc
    67381 acaaaccgac cacgaacaag tcatctatac gaactttgcc tttatggtgg ggatccatgc
    67441 ccgctcttac gggacgattt tttcgaccct ttgcagtagc gagcaaatcg aagaagcaca
    67501 tgaatgggtg gtctcaacac agagcttgca agaccgtgcc cgtgtcttga ttccttacta
    67561 tacgggtgat gaccctttga aatcaaaagt agcagcagct atgatgccag gatttttgct
    67621 gtatggcggc ttttaccttc ctttttacct atcagcacgt ggtaaaatgc caaacacatc
    67681 tgatatcatc cgcctgattt tacgcgacaa agttattcac aactattaca gcggttacaa
    67741 ataccaacaa aaagtagcac gtcttagccc agaaaaacag gctgaaatga aggcctttgt
    67801 ctttgacttg ctctatgaac tcatcgacct tgaaaaagct tacttgagag aactgtatgc
    67861 aggctttgat ttggcagaag atgctatccg ctttagcctt tataacgctg gaaaattcct
    67921 tcaaaattta ggctatgatt cgcccttcac agaagaagag acccgtatct cacctgaagt
    67981 atttgctcag ctatcagcgc gtgcagacga aaaccatgac tttttctcag gcaatggctc
    68041 atcttatgtg atggggatca ccgaagaaac cacagatgac gattgggagt tttaagaaat
    68101 ggcagagctg attattgtgt atttttcatc taagtccaat aacacccatc gcttcgtcca
    68161 aaaattaggc ttgcctgctc agcgcatacc agtagataat aggccacttg aagtttcaac
    68221 ccattacctt ttgattgtgc ctacctatgc agctggtggc tcagatgcca aaggagctgt
    68281 ccctaaacaa gtgattcgtt ttttgaataa tcctaacaat cgtaaacatt gtaagggagt
    68341 gatctcttca ggaaatacca attttggcga tacctttgcc ttagcaggcc ctatcatttc
    68401 tcaaaaattg caggtcccct tattacacca atttgaacta ttaggcactg ctacagatgt
    68461 caaaaaggta caggcgattt ttgcccgctt aaagcatcac acacacgaca agcaaaaaca
    68521 aaccaacaac ctgattacag aaaggacaca cccatgtcac aaaccaatgc gtcatacctc
    68581 tcattaaatg cactgactcg ttttaaaaaa ccagacggca gctaccattt tgatagcgat
    68641 aaagaagctg ttaggcgcta cctggaagaa catgtctctc ccaatcaaat ggcttttaac
    68701 tcactagaag ataagctagc ttacctcatc aatgaagggt attatgagca ggccattttt
    68761 gatgcctacc ctaacgacct tatcaaggag gcctttcatt atgcctatca acaaggctat
    68821 cgctttttaa atctcatggg cgctatgaaa ttttaccagt cctatgcctt aaaaaccttg
    68881 gatggtaagc agtatctaga aacatttgaa gaccgtgctg tgatgaatgc actcttttta
    68941 gctgatggag atcaaacctt tgtctttgac gtgattgatg ccatcttgca ccgacgcttt
    69001 caaccagcta ccccaacgtt tttaaatgcc ggaaaaaaac gccgtggcga atacatttcg
    69061 tgctatcttc ttcgtgtcga agacaatatg gaatctatct ctcgcgccat tagcaccagc
    69121 ttgcaacttt caaaaagagg aggcggagtc gccttgtgtc tcaccaacct cagagaaatc
    69181 ggagcaccga taaaagggat tgaaaatcag gcaacaggca ttgttcctgt catgaaacta
    69241 ctagaggact ctttttccta tgccaatcaa ctaggtcagc gccaaggagc aggtgcggtt
    69301 taccttcatg cccatcaccc cgaggtcctg acctttttag acaccaaacg tgaaaatgcc
    69361 gatgagaaaa ttcgcattaa gtccctagca ttgggacttg tgatcccaga tattaccttc
    69421 cagttagcca aagaaaacaa agacatggca ctcttttcac cctatgatat caagcgtgcc
    69481 tatggcaagg acatgtcaga catctccatc acagaggaat acgataaact gctagtcaat
    69541 ccagccatca aaaagaccta catcagtgct agaaagttct ttcagttcat tgcagagcta
    69601 cattttgagt caggctaccc ttacctcttg tttgatgaca cggtcaataa gcgcaaccct
    69661 catgccaaaa aaggcagaat cgtcatgtct aacctgtgtt ctgaaatcgc tcaagtcagc
    69721 accccaagca ctttcaaaga agatttgagt tttgaaacca ttggagaaga tatctgctgt
    69781 aatttagggt ctatcaatat tgcccaggct atggcagatg cgccacactt tgaacagctc
    69841 atcacaacga gcatcagagc acttgatcgt gtctctagag tgtctgacct gaattgtgcg
    69901 ccttctgttg aggcaggcaa tgcagccaac catgcagtag gattaggcgc catgaaccta
    69961 catgggtttt tggcaaccaa ccacatctac tatgatacaa aagaagccgt tgactttaca
    70021 gatctgtttt tccatgccat ggcctattat gcttttaaag cctcttgcca attagccaaa
    70081 gaaaaaggcg cttttgcagg attttcgtta tcaacctatg cagatggcac ttattttgcc
    70141 aagtatttgc aagaagatgc caagccacaa acagccaagg ttgccacatt gttgcaagat
    70201 tacggcttca cattgccaac ggtggcggat tggcaagccc tagtagcaga tatcaagcag
    70261 tttggcctag ccaatgcaca cttgctagcg gttgctccga caggctccat cagctactta
    70321 tcatcctgca ctccgagtct acaaccagtc gttgctcctg ttgaggtccg aaaagaaggt
    70381 agcctgggca ggatttacgt ccctgcttat cagattgacc aggctaacta tgcttactat
    70441 gaacgtggtg cctatgaggt cggcccaaaa gccatcatcg acgttgtcgc tgctgcccaa
    70501 aagcacgttg accaagccat ctcattgacc ctgtttatga ccgataaagc gaccacacgt
    70561 gaccttaacc gctcctatat ccaagctttt aaacaaaact gtgcatcgat ctattatgtg
    70621 cgagtgaggc aagacgtcct agcaggcagc gaacagtatg acgaggatag tcttgtgaca
    70681 gcttctggag ctagtgatga gaccaccaca gagtgtcaaa gctgtatgat ctaacagcta
    70741 ctagaaagct ctcgtgtccc ctatcacatg cataggatca gtgcgcacga cctttcaaga
    70801 caagcaagca tcagctcttg cttgtctttt tttggcctca aagcccgtta gtctgctgct
    70861 atgcgaggct tttttttgag catcagaacc tcaaaaaaaa ggacatggag tccttttttg
    70921 gtgatcggtg ttgaggccgt cacaaactgc ccttgaagca cgcttctatg tggagctttt
    70981 tgtggtcctg tgacacgtaa gctccaacga cctccagctg acagcctctt ggaaacaaga
    71041 gctcaacctc tgaaggcaca gccgaataag gctcgacaaa ggctgccttg gccccttttt
    71101 tgacacagat gcgcacctcc accggtcgat gggtcatggc gccgtttttc aagactgtcg
    71161 tgctcataaa actgtgcttg gtgtagcgtg taccaagctt gatcttacaa aggatatgag
    71221 ggtcaaactg atggttacga tagtaagacg tgatatcagt gtgtgaaaca ccgatatcac
    71281 gcaaaaacgt ctcgtataca tagcggtata ctacaatgtt ccacgggatg actagccggt
    71341 gagtcgcagc atcgagctgg gccacctgat cccttagctc aggcgtgagt tggctgagct
    71401 cacctttggc cttgtctagg ctggtgttga tagggcctgc ctgctgacag gtataagcag
    71461 ccatcgcctc ttgctcagcc cttgggtaga tgagaccctt gccccagcgc tttttaatca
    71521 gtgtctcagc gcccttttga tccgaaaagg taaaataagc aggcgtcccc tcacaaaccg
    71581 cccgctcata gtgctcacag acaaaaagct cgaccaagcc ctcagtttgc cagatcagac
    71641 taaaacagct aagaagaagg acaatagcca gttgatagcg cttttttagc atagttcccc
    71701 ctgacaccag cccaaaaggc tgacccttcc cctaggcctt ttggctagct catgatacca
    71761 ccagtttctc agacaggcta atctttttgt catctctttc tccctaaaca gactctctta
    71821 tcatgatatt atgctattat gagcgatttg tcaatccata gcaatcgttt tttagttaga
    71881 taagtaagct tttgacctag aggcagacaa gagtggcagt acctcccgtt cactgtggtg
    71941 gctaataagg actaacacaa aatctcaaac gctttcaaaa acagctcctg agcttaaaaa
    72001 aggctgatga acaatttttt tgagtttaag agagattgcc atgattttct aatcatttga
    72061 tgtttaaaat gataaaaaca tgaacttgaa atgaaagaat acgagtagta aactataact
    72121 atatcaaaat gatggaatgg agtgatttta tgaaaacaaa atcaaaacgc tttttaaaac
    72181 tagcaaccct ttgcttggcc ctactaggaa caactttgct aatgacacgt cctgtaaagg
    72241 cggaggtggt gatgacccag agcctagctg agggtagtaa tagttcagaa aaaaatagtg
    72301 agcagcagga ccaggataaa gtacagcaaa gaggtgatag taaagaagat tgggatagag
    72361 ggtatgatga tggttacaag aagggtgaag aatcagatac tcgagaggaa ttagatagaa
    72421 gtacttttga cagttttccc ccaggtatat cggatcaagg agagtatttg gatggctatg
    72481 aagggggata tgaagcagga tggcgtaaag gtcatccagt agaagcattc ctggagatgg
    72541 catggcactt cttaacatat gcatttacta gtttatttgg taaccacggt tcttagtaat
    72601 tgatctattc gttttttaat ttagttatta atgataaaaa aactagaggt gtatattaaa
    72661 cgtatcaaat aataacgaaa tggagtgatt ttatgaaaac aaaataaaat tagcaacctt
    72721 ttgcttggtc cttttgggat caaccttact agtgacatac ccagtaaaag cgacagaaac
    72781 gccattaagt ggatatgagt ctactgaaca agctctacct aaatccaatc aagtaacgga
    72841 gaccttacat agtgaagggg atttacaaaa aattgcagaa aaaagcgacg atgggtataa
    72901 gcttgggtat caaaaggggt atgaagctgg tcgaaaagaa gatgcttccg aaaatccaga
    72961 cgaaaataaa ttagaatcta agtctcttga ttatattagt ggttattacg caggatatta
    73021 tcgagggtgg gatgaaacta acaaaccttt ccaaacatta ttagaagata tttatcgttg
    73081 gttatgggaa attttcttta aaccgtaagt aaatgttaat tattcattaa aatatagtca
    73141 taaaatgtga taacatctat ttattatagt tattttactt gaggaagata gtaccttgta
    73201 tgcatgcaga agcatattat aaagatctgc tataattggg atagtccctt tagtagtcag
    73261 gccacctctg ataggggtgg cttttttggg ttttagtgac ccgtgtgttg agaaaggagc
    73321 atttatgcca gaaaagaaag tgttgcccgt ccgttgccta atatgaaccg acagttattc
    73381 cctattaaaa tagacgcaaa tatccacgct ttcactgtag ttgctagtaa ggtctaacac
    73441 aaaacatcaa aggctttcaa aaacaactcc taagcttaaa aaaggctgtt taacagattt
    73501 gttgagctta agggagattg ccatgatttt ctaatcattt gatgtttaaa atgataaaaa
    73561 catgaacttg aaatgaaaga ctgctagtag taaactaagc ttatcaaaaa aatgaaaatg
    73621 gagtggtttt atgaaaacaa aatcaaaacg ctttttaaac ctagcaaccc tttgcttggc
    73681 cctactagga acaactttgc taacgacaca gcccgtaaag gcggaggaag ggcaaaataa
    73741 gcaacaggaa gtgtctgtca gcagccagtc tggacaatct gaaggagaag acttatcgga
    73801 ggattcagac gataagtatc catatgctga aggtcatgaa gctggccaag attttggata
    73861 taaagaagga ttaaaggcag gttggcagga agctgatcct aaagaaccaa aggatattcc
    73921 tgaacccgaa tttaatccat atgaatctga aggagaagac cgtaatgatt tcaaagaagg
    73981 atttcgcgac ggatatcctg caggatacgt tgaaggatgg agaaaaagtc atccattatg
    74041 ggcaatcgtt caagatgtct tgccttggct ttataatttt ttaagataaa atagtgtata
    74101 atactagccc tgacagttct ggcctacgcc tactatgacc tacctaaacg acatccaaag
    74161 agtgagggaa ctacgaggct gggcaaaaac tagcttcgac ataaaaccac actgcagttc
    74221 tttccatctt gaaaatactc aagatgaaag aattacgtgt ggtttttgat ttttaaaagt
    74281 tttagtaact aaattctttg ccaattttgt gagattcatg ctcatgaaga gacatccgac
    74341 ctccgtttgg acgaattaat tgcctcaaac gtgaactctg cgtacgctaa aaatactctt
    74401 caatctacca aaaacgggtt cgacatcgat tttccgttta gcgtagatat gagagccctc
    74461 ttcgctatgc aattgttcct ttatgagttc cttaaaataa ttccaagtcg gattataatg
    74521 gatttgtttc tgacgatcac tttctgtttt agccagttat tctagctctg gcgtgtcctg
    74581 tattttatct gcctcgtaaa ttttgaaatc tcgtttaaac ccgtacttgt cgactcgacg
    74641 agagtaagat ttaaaagaat agacaatccc atcaggtttt ataatctggt ctgtctctcc
    74701 aagatagtcc cagttagctg ggttctccgc actgttctta tatttctgag tcaattcctt
    74761 ttggtacatg ccatagggaa taagagctgt tttctccaac tcatcaataa taaaacgata
    74821 attttcttcg ctaccataac ctgcatcggc cataatattt tggaataagt ccaatgtttg
    74881 attggattgg aggaagggtc ttagggttct gatatcggtt gggtttgcaa agatatcata
    74941 agcaaggata tattgaccat tagtcgctgc ttgaacatta taacctggtt tcagctgacc
    75001 attcttcata tgactcgctt ttatatttta aggcttgtga agaaatagtc tctcccagac
    75061 tatttctttc ctttattcgc ataaaggtag cgtcaggatc agttctagaa aaagagttgc
    75121 gttcttgaag aatttctctc gcctcctcat atcgctgttt acgaggaata taatctttcc
    75181 tcaactgatt gcggaatttc ttgatgcgct gccgtttttg tgtattaacc gaactacctt
    75241 ttatcacttt tggttcttga gtgatcgctt tttctacttc atcaagggct tctttccctt
    75301 tttcaagcag cacgttaagt ccttcgctag tttcatattc ttcttttgaa agggctaaag
    75361 ttaccccttc ttgaatgagc ttatcataga gttaagaaat gtttccattg tctctcaaga
    75421 gcaaggtaaa ataaataaaa gtagtcttaa tcaggttatt ggcaggctta ctcgaacggt
    75481 cttattgatc gttttatagc taacataagt gtcttgactt agccatttca tcggaataac
    75541 ttcttcgttc atctgcacca ttttacgacc agaaaagacc tgacgactat aggcaaagag
    75601 tgtcattttt aaaagcatag caagatgaaa agcaggtcgg ccagtatgag acttttcttc
    75661 aagtaaaatc aacgctgaag actttttgga ttcccataat tgttaactac atcattttag
    75721 agcaatcata tagagactaa gacataattt taccaaagtt ttgaaggcta ttgaagagta
    75781 actttcttct ttaatatatt taataaattt tcgcaagttg tcaagtcaag tgcaacgagt
    75841 tcatagataa ctagagttcc agaggttaag ctgttcgggc tagctcaaac aggaatgttg
    75901 aggattgata ttgaagaagt cgtcttgggc gttcattgat ggctgtaaga taattgtcaa
    75961 attcttcaga ggttagtgaa ttaagagaga ttcctttagg gacatattct ctgaggaggc
    76021 cattgaagtt ctcgtttgtt cctctctcat gtgaagaata gggatgtgca aagtaaacgt
    76081 caacagcttc taaggttgag agtaaactaa actcagaacc attatccgct gtggtggatg
    76141 caataggata ctgactgatg agatgcgtga cagcacggtt aatggtttgg gactgcttgt
    76201 cttctagctt aactcctagt gcatagcgtg tctggcgctc taccaaagtc aacataacag
    76261 cttcaccttt ggttttcttg ccgagaacca aatcaatctc ccaatgccca aattcagaac
    76321 gatcattaat atattctgga cgttcttcga tagatttacc taaagtcttc ttattcgttt
    76381 tcatgacttt cttagaacgt tttctgatac taaccatctt aggcaaatcg attggtttca
    76441 tagacacgtt gtctactatc agcgaaatag gcgttgaaga aggtttgttt tccattctta
    76501 tcctttacct gatctactga accacgtttt atttctcggc agattgtaga acggtgacta
    76561 cccagaagtc gagcaatctc aacgggtttc tttcccattt taagataagc agcaatttca
    76621 ccgcgttctg tggctgaaag atgagaatag gaggattttc tggtaaaatt aatattagac
    76681 atgttcatct gctttccata ctgaattggg gaattctagt atatcagacg aacatgtctt
    76741 ttttgttgca cttcatttta caacgcggga aaatataaaa tatatctttg agcaaggtag
    76801 ttattcttga aaatttgaga atatattgtt aaagacatca aaaaacagta cctatcaaga
    76861 tacagtcgta tttctttaaa ttatgctaaa aactgcagat gataaacatt tattaaacta
    76921 ttcgaagtta attgaaaaga atgcctaata tcgttgttct atttcataat attgataaat
    76981 aacatatcac gatacgagat atcaggtaag ttaggttact caagaaacgt cgttttcaac
    77041 tgacataaaa caactttaag agagaataag cgaccaaaaa gagcacttaa cagagtgtgc
    77101 aaattattta atagagataa agtgtcaaat aggctcttga ctatagacga tataaagata
    77161 tcttgaagta ttagcatatc ccaataaaat agtgaaacat taagtgagca gcagctactc
    77221 agagagatca aggacttctc cggtcgcctc agccaatcaa tccctatctt tttagcgcaa
    77281 gaattggtat aataaccctt gtcttaaaaa atgagcaaaa ggagagaatg aaatgaaaaa
    77341 gacattaacc ttgctactgg cactctttgc catcggggta actagtagcg tcagagcgga
    77401 ggatgcaatc aagtgggaac tagatccaga aacttctcaa aatagtccaa ttgctgtgaa
    77461 cgttgataac gctaataaac tacggttcac actacctaca ggctggtcgg tatcttttaa
    77521 aagaaaaaaa gatcattaca atcctctaga ggtaaataat aagctagtat ctgagacaaa
    77581 aaacagaaat actagtccta ggatagtaga ttatggtaaa aatggtaatc ctattttagc
    77641 tatttataat gataaccaag ggtcatcagg tttaccaatc actgtaactg tcgataaacc
    77701 aaatgaagga gacgaattaa cactgcttta tcgtgccgat gatggttttt ttggcggatt
    77761 tacaaaatta aaagattcga agacactaaa aaaagaaaag aaggagaaag aaagacagct
    77821 agcagaagaa aaacaaattg aggaagagag aaagcacgtt gaacaaaaac agctagaaga
    77881 aagcatgcta aagcagataa gagaagaaga ccataaacct tggcatcagc ggttaagcga
    77941 aagcatccaa gatcagtggt ggaactttaa gggactgttt cagtgagggt ttgctaggct
    78001 atgaggttgg ctaaagcaca agaggctagg caaaaactag ctttagcata taaaaaacga
    78061 gcatttccgc agtcggagat gctcgttttc ttctgccatg gtttataatt ataataacgg
    78121 caaaacaact agaaagccat gacgatgtat aaagagtata acacaaatca attaagtttg
    78181 gaattaaatc ttgcttttga tatcctgata acgcatgaag caagactgat tagtttgttc
    78241 gtggacagta tccctaatca tgttttaatt aaagatacta aaattcttga tattcataaa
    78301 gctcaatcag gaaggacaaa atcaaagagc ttaccagttt tctggtaatg ctgatcatgt
    78361 ctcctttgat atacctgtta gctacagctt ttttcaattc gtgatatgtt aacattttta
    78421 tcctcctact taatctattc gtaaaaaatc tcttaaaata gatatttaaa aaaagtccat
    78481 tataacggat atgcccgtgt gcgaatacat gttcgggtaa atattttaaa tcaagatgtt
    78541 tgatgtttgt gtgtgcaaaa acaaaaaaat cgccctcgat tgatgatatg atacgtctta
    78601 agtagacagg ctaaataacc aaaatctact caagaggtat ttttatgtca gaaaagaaag
    78661 ggctgctcgt attaagcatg gtagtgagcc ttgtgtccct gcttgatcat atcttctttc
    78721 tgctacttat agttatcttt acttgccgct tgtagcaagt agtctagcta ttattagtct
    78781 ggtgcaaaac aaaggcaggc aaaaggtttg gtcgctagct gggctcgttt tagcagctct
    78841 agctgtggca gtagtggcct atgcccaacg gttattcctt atcaaatgca aagtccctcc
    78901 ctcttatata aactatcaaa tactttcaaa aacagttcct aaagctcaaa aaggttatct
    78961 aactgctcca agcgggcact ttctgtgata aggatagctt gccatttttt tctaatcatt
    79021 tgatatttaa aatgataaaa aaatgaactt gaaatgaaag aatgcgagta gtaaactata
    79081 accgtgtcaa aaaataatga aatggagtga ctttatgaaa acaaaatcaa aacgcttttt
    79141 aaatctagca accctttact tggccctact aggaacgact ttgctaatgg gacgtcccgt
    79201 aaatgcggat aatgcggata tggatggata tggaagtgag tcaaaagttc aacgagaaca
    79261 aagtccatat gaaaaaggtg tgagagatgg ccatgacgca ggttataagc aaggcaaaca
    79321 ggatagacaa caaggatccc cagatgcttc tcctacccct ccagataaac ttagagtacc
    79381 tgagcctgag agtaaccctt ataataagga tcatgataag cagaataacc agagatacaa
    79441 aaatggctgg gatattgcgt accgctcttc ttattatact ggctggtatt ctgctgaagg
    79501 gacaggtcat ttagaaagcg atgattatcc aaatgaagag gaaggagaag atatttctga
    79561 caactctcct tcacagggtt caacaggttc aacagatgac ggtttttcta atctcattga
    79621 tatggttgtt gatattacca catttctttg gggtctagtg tcaaattggt tttaaaatga
    79681 tactttagtt tgagcttcgt agcttagatt taccgagaaa taatatacta aataaattat
    79741 ttttaaataa caggggagat acttaatttg aggatacttt ccttagctca agccattccc
    79801 acactaatct gctataattg ggatagtccc tttagtagtc aggccacctc tgataggggt
    79861 ggcctttttt gaggttgtag tgacccgtgt gttgagaaag gagcatgtat gccagaaaag
    79921 aaagtgttgc ccgtcttaag catggtggtg agttttgtct gcctgcttga tcatatcttc
    79981 ttttttgcta cttatagtta tctctacttg ccgcttgtag caagtagtct agctcttatc
    80041 ggcctagtgc aaaacaaagg caggcaaaag gtgtggtcgc tagctgggct cgtcttagct
    80101 gctatagccg tggcagtagt ggcctatgcc tactatgacc caaccgtcat cccctactaa
    80161 ccttaacctc cccttcgcac gcaatcagca ccacaaaaag cacccctgac aggtgctttt
    80221 tgtgctttag ccaacctcat agcctcgtaa accctcactg aaacagtccc ttaaagttcc
    80281 accactgatc ttggatgctt tcgcttaacc gctgatgcca agatttatgg tcttcttctc
    80341 ttatctgctt tagcatgctt tcttctagtt gttttcttaa ttcattatcg cgtttttttg
    80401 cctcttcttg ttcctgtgct ttttccgctt gcaaccttgt gttttgtgtt ttttcatctt
    80461 cgaagactag tttacccaag taaaaatgac catcatttgc aaaggataga gtaactacgt
    80521 ctccaactgc aagtggtttt tgtagttgga cggtataatt cccatattta tcagcacgat
    80581 ttccgcttat catccaagta cgctcagtac aggtgctttg ctctgctgga catgtaacag
    80641 tgatttattt aagatttgtt ttaatttttt gtgtttctcc gtttttatgt tttatagaag
    80701 catatacgta accgtttgat tggagggtga tgtcaatagt ttgctctcct gttttaaaag
    80761 gtgagactgt aactgttggt actgtttgtt gaccgatagg tttaaattca aatacctcct
    80821 ccgctttgac gctactagtt atcccgatgg caaagagtgc cagtagcaag gttaatgtct
    80881 ttttcatttt tccctctcct tttgctcatt ttttaagaca agggttatta taccaattct
    80941 tgcgctaaaa agatagggag ttcatgtctt gtggttggga aatggcgcga ctatccttgg
    81001 taggggcaga caggctgacc aaagttccta tcttgcctgt tggtggattt tgaacttaaa
    81061 gcctctctga ttgcagtcgg taggcttttt tgatgctttt tcgtactttt tttatttatt
    81121 acgctaaaaa atgttatact tgatgaagaa aaaggagagt ttagaacgtt aagatatctc
    81181 acagcagatt gatagaggat atggaagaag gttagctttc ccaagagatg ccgtttggga
    81241 atggtataac aataactggc agaagttata agtaaaacaa gaataaatta actcagatga
    81301 tttttagacg ttcccacgcg tgtgcgaatg cgtgtgtgaa ttgatgttat caataaatcc
    81361 tttaataacg cctttttcga acaggaaaca aatttattat cccacgtgtg tgcgaatgcg
    81421 tgtgcgaatt aattggagaa aaaatgagaa aatacgatat acaaaaattg ttattatcag
    81481 gggagaacca aagtgttgaa tttaaagaag ctaaaaattc ttttcctaaa gacggtatga
    81541 aaacaatttg ttccttcgca aatacaaata atggtctgtt aattctaggt gtctcagaaa
    81601 acaccaagaa taaagatttt tatatttctg gcgttaatga ttccgataaa gtattggacg
    81661 aattatatag tttacttaat aaccctaata aaattaatag aaatgtgatt aacgaggaaa
    81721 gtgttgaggt cacaaatgta aaaggaaaag agattatcat tatccctgtt aacaaagtag
    81781 attacaagga taaaccaata tatcttaatg acaatatagc atctacctat tttcgtcagg
    81841 ggactggtga ttttaggtgt tcacaagaac aaatcaatgc gatgctaaga gattctgcaa
    81901 aagaaagttt tgatagtacg cttgttcaga atttctctat atcagatcta gatagagaaa
    81961 caataaaccg ttatagagaa aaattcgatg atattaatgc tgaacaccct ttttccaaat
    82021 tagacaccga gcaatttctc ttaaaaataa acgctctaag aagagatcgt acagacaaca
    82081 aaataaaacc aactgtggct ggattactga tttttggaac acataatgcc ataaaagagt
    82141 ttattcctca ctataacgta gaatatgttt taaaagattt taccgaaaat aatcgcttta
    82201 aagatcgagt catttatgat ggtacgtggg gagaagataa tctttttaat ttctttcacc
    82261 tagttattga aaaattgtat ctaactttaa atgataactc taatattcaa gaaaattctc
    82321 tgaatagaat tgggatttca aagttacgaa ttgcaattcg tgaagcattc gttaacagcc
    82381 ttattcatag tgattataag agcgaaaaag ggataatggt aattagatat tctgatagat
    82441 atatatttac aaatggcggg acacttagaa tcgacctaaa ggactttttt agtggggcac
    82501 attctgatcc aagaaactac ttaatacaag aaatttttag gtttctaaat ttatgtgaaa
    82561 aagcgggaac tggtatacct aaaataatgg aagcagttaa agagagtcgt ttaaaatatc
    82621 ccaaattacg aactcaatta gactcagttg aacttacatt atgggatact tc
//
LOCUS       DAUGOH010000004        78086 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUGOH010000004 DAUGOH010000000
VERSION     DAUGOH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 78086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78086
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.004"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..303
                     /locus_tag="VH957_000245"
     CDS             <1..303
                     /locus_tag="VH957_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEQ8558191.1"
                     /translation="KKEIEIIDKKINRLNDLYINDLIDLPKLKKDIEELNHLKDDYNK
                     AIKLNYLDKKNEDSLGMLMDNLDIRKSSYDVQSRIVKQLIDRVEVTMDNIDIIFKF"
     gene            complement(480..1391)
                     /gene="whiA"
                     /locus_tag="VH957_000246"
     CDS             complement(480..1391)
                     /gene="whiA"
                     /locus_tag="VH957_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ8558192.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFDLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            complement(1388..2365)
                     /locus_tag="VH957_000247"
     CDS             complement(1388..2365)
                     /locus_tag="VH957_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEQ8558193.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNENDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            complement(2362..3252)
                     /gene="rapZ"
                     /locus_tag="VH957_000248"
     CDS             complement(2362..3252)
                     /gene="rapZ"
                     /locus_tag="VH957_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEQ8558194.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            complement(3667..5013)
                     /gene="asnS"
                     /locus_tag="VH957_000249"
     CDS             complement(3667..5013)
                     /gene="asnS"
                     /locus_tag="VH957_000249"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEQ8558195.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVTNKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVTKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            complement(5034..6227)
                     /locus_tag="VH957_000250"
     CDS             complement(5034..6227)
                     /locus_tag="VH957_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8558196.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            complement(6562..9063)
                     /locus_tag="VH957_000251"
     CDS             complement(6562..9063)
                     /locus_tag="VH957_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEQ8558197.1"
                     /translation="MFCFIDIACYNRLTMIQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFTR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRKDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            complement(9171..9935)
                     /locus_tag="VH957_000252"
     CDS             complement(9171..9935)
                     /locus_tag="VH957_000252"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEQ8558198.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHVDGFKIGILDYNEETAQAAVD
                     KLSPEDAVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLAGDDSNYITGQTIVVDGGMVFH"
     gene            10103..10801
                     /locus_tag="VH957_000253"
     CDS             10103..10801
                     /locus_tag="VH957_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8558199.1"
                     /translation="MPFIFRYSFFNKVLIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIINVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            complement(11111..12040)
                     /locus_tag="VH957_000254"
     CDS             complement(11111..12040)
                     /locus_tag="VH957_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558200.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(12033..12725)
                     /gene="ftsE"
                     /locus_tag="VH957_000255"
     CDS             complement(12033..12725)
                     /gene="ftsE"
                     /locus_tag="VH957_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEQ8558201.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            complement(12744..13842)
                     /gene="prfB"
                     /locus_tag="VH957_000256"
     CDS             complement(join(12744..13769,13771..13842))
                     /gene="prfB"
                     /locus_tag="VH957_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEQ8558202.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            complement(13911..15035)
                     /gene="queG"
                     /locus_tag="VH957_000257"
     CDS             complement(13911..15035)
                     /gene="queG"
                     /locus_tag="VH957_000257"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEQ8558203.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRIYPERHLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKNEDSRKELELIRHKWQV"
     gene            complement(15731..16380)
                     /locus_tag="VH957_000258"
                     /pseudo
     CDS             complement(15731..16380)
                     /locus_tag="VH957_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            complement(16677..17312)
                     /locus_tag="VH957_000259"
     CDS             complement(16677..17312)
                     /locus_tag="VH957_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ8558204.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGMSFIRAIKSPLPQVEVMV
                     TGGISLDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            complement(17317..18318)
                     /locus_tag="VH957_000260"
     CDS             complement(17317..18318)
                     /locus_tag="VH957_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ8558205.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADATMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLANQRDVQR"
     gene            complement(18347..18988)
                     /locus_tag="VH957_000261"
     CDS             complement(18347..18988)
                     /locus_tag="VH957_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ8558206.1"
                     /translation="MKIALINENSQAAKNGIIYDALTTVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKGRAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVTYLKSVLEQ"
     gene            complement(19013..19807)
                     /locus_tag="VH957_000262"
     CDS             complement(19013..19807)
                     /locus_tag="VH957_000262"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEQ8558207.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            20131..20568
                     /locus_tag="VH957_000263"
     CDS             20131..20568
                     /locus_tag="VH957_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8558208.1"
                     /translation="MIAIIVMGHGHFASGIVSALELIAGKQEKVTAIDFTAEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVLGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            20568..21767
                     /locus_tag="VH957_000264"
     CDS             20568..21767
                     /locus_tag="VH957_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEQ8558209.1"
                     /translation="MARSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTSEAREAALKAADKLVQRYQDKGGFIQ
                     AWGVLGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDHDKKTYE
                     AAMHSMLRALIKDYANKDLNPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            21803..22291
                     /locus_tag="VH957_000265"
     CDS             21803..22291
                     /locus_tag="VH957_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8558210.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKYLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKHLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAICCLAHDHQVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            22310..23092
                     /locus_tag="VH957_000266"
     CDS             22310..23092
                     /locus_tag="VH957_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8558211.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWSFAILGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            23079..23900
                     /locus_tag="VH957_000267"
     CDS             23079..23900
                     /locus_tag="VH957_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8558212.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVLLTVLIGIIGSWLGILA"
     gene            23987..25894
                     /locus_tag="VH957_000268"
     CDS             23987..25894
                     /locus_tag="VH957_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEQ8558213.1"
                     /translation="MSLAFTRFKETVNPDFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQKAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFNALTKQEESLIL
                     ASLEKQLQFLHTNYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPALDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSICLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQINSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGMFLIIDTIQAQGNHCLVSQFILDNHLEVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALAWHLKGKQFDYSICVLQEDLIKGEKLVLLNGHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            25958..26953
                     /locus_tag="VH957_000269"
     CDS             25958..26953
                     /locus_tag="VH957_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8558214.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGKFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(27037..29718)
                     /locus_tag="VH957_000270"
     CDS             complement(27037..29718)
                     /locus_tag="VH957_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEQ8558215.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTMLVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(29948..30334)
                     /locus_tag="VH957_000271"
     CDS             complement(29948..30334)
                     /locus_tag="VH957_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEQ8558216.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            30416..31717
                     /locus_tag="VH957_000272"
     CDS             30416..31717
                     /locus_tag="VH957_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8558217.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSRGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMMQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            32173..32982
                     /gene="yidA"
                     /locus_tag="VH957_000273"
     CDS             32173..32982
                     /gene="yidA"
                     /locus_tag="VH957_000273"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEQ8558218.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            32982..34208
                     /locus_tag="VH957_000274"
     CDS             32982..34208
                     /locus_tag="VH957_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEQ8558219.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLGIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            34195..35430
                     /locus_tag="VH957_000275"
     CDS             34195..35430
                     /locus_tag="VH957_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8558220.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(35529..36287)
                     /locus_tag="VH957_000276"
     CDS             complement(35529..36287)
                     /locus_tag="VH957_000276"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEQ8558221.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(36528..37724)
                     /gene="tuf"
                     /locus_tag="VH957_000277"
     CDS             complement(36528..37724)
                     /gene="tuf"
                     /locus_tag="VH957_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEQ8558222.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            complement(38078..39382)
                     /locus_tag="VH957_000278"
     CDS             complement(38078..39382)
                     /locus_tag="VH957_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEQ8558223.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILA
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            complement(39522..42320)
                     /gene="ppc"
                     /locus_tag="VH957_000279"
     CDS             complement(39522..42320)
                     /gene="ppc"
                     /locus_tag="VH957_000279"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEQ8558224.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQTIIAEEVALLKEMLENITRR
                     MIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINHQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMNSSVGLNTSAWPSPASLEKPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            42479..44278
                     /gene="pepF"
                     /locus_tag="VH957_000280"
     CDS             42479..44278
                     /gene="pepF"
                     /locus_tag="VH957_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8558225.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEESLQDIDLFKRN
                     YEDRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIRDKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYTSVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVMSTAGYLNLKNNPDGAKEWLDFLKSGGSRTPFDTAMLIG
                     ADIATEKPLRDTIQFLSNTVDQIINYTEEMSHA"
     gene            44271..44750
                     /locus_tag="VH957_000281"
     CDS             44271..44750
                     /locus_tag="VH957_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEQ8558226.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFAWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(44796..45182)
                     /locus_tag="VH957_000282"
     CDS             complement(44796..45182)
                     /locus_tag="VH957_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEQ8558227.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQIQTTPSVPKADHHVRLVV
                     KEDTNTIDEKVSFGKGDTVLEILKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNG
                     KMADKGVDQITVKDGDSIEFYQEVFK"
     gene            complement(45166..45669)
                     /locus_tag="VH957_000283"
     CDS             complement(45166..45669)
                     /locus_tag="VH957_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8558228.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGCQ
                     AFLVALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            45994..46842
                     /locus_tag="VH957_000284"
     CDS             45994..46842
                     /locus_tag="VH957_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEQ8558229.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKASTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFTTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      46969..47065
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            47110..47673
                     /gene="thiT"
                     /locus_tag="VH957_000285"
     CDS             47110..47673
                     /gene="thiT"
                     /locus_tag="VH957_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEQ8558230.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMALSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     gene            47764..48243
                     /locus_tag="VH957_000286"
     CDS             47764..48243
                     /locus_tag="VH957_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEQ8558231.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            48584..49207
                     /locus_tag="VH957_000287"
     CDS             48584..49207
                     /locus_tag="VH957_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8558232.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNTSLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(49315..50217)
                     /locus_tag="VH957_000288"
     CDS             complement(49315..50217)
                     /locus_tag="VH957_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8558233.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DAAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            50391..51884
                     /gene="lysS"
                     /locus_tag="VH957_000289"
     CDS             50391..51884
                     /gene="lysS"
                     /locus_tag="VH957_000289"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEQ8558234.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKYFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            52020..52160
                     /locus_tag="VH957_000290"
     CDS             52020..52160
                     /locus_tag="VH957_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558235.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(52257..52469)
                     /locus_tag="VH957_000291"
     CDS             complement(52257..52469)
                     /locus_tag="VH957_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEQ8558236.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(52681..53967)
                     /locus_tag="VH957_000292"
     CDS             complement(52681..53967)
                     /locus_tag="VH957_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8558237.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(54069..54995)
                     /locus_tag="VH957_000293"
     CDS             complement(54069..54995)
                     /locus_tag="VH957_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8558238.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            55194..55478
                     /locus_tag="VH957_000294"
     CDS             55194..55478
                     /locus_tag="VH957_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEQ8558239.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM"
     gene            complement(55638..56066)
                     /locus_tag="VH957_000295"
     CDS             complement(55638..56066)
                     /locus_tag="VH957_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ8558240.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEDDIIIDYTEQDEPVSDTLDKH"
     gene            complement(56059..56466)
                     /locus_tag="VH957_000296"
     CDS             complement(56059..56466)
                     /locus_tag="VH957_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEQ8558241.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(56488..57267)
                     /locus_tag="VH957_000297"
     CDS             complement(56488..57267)
                     /locus_tag="VH957_000297"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEQ8558242.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(57264..58196)
                     /locus_tag="VH957_000298"
     CDS             complement(57264..58196)
                     /locus_tag="VH957_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEQ8558243.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(58561..58833)
                     /locus_tag="VH957_000299"
     CDS             complement(58561..58833)
                     /locus_tag="VH957_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEQ8558244.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(58897..59334)
                     /locus_tag="VH957_000300"
     CDS             complement(58897..59334)
                     /locus_tag="VH957_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEQ8558245.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            complement(59321..61453)
                     /locus_tag="VH957_000301"
     CDS             complement(59321..61453)
                     /locus_tag="VH957_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEQ8558246.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            61687..61842
                     /locus_tag="VH957_000302"
     CDS             61687..61842
                     /locus_tag="VH957_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558247.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            61990..62892
                     /locus_tag="VH957_000303"
     CDS             61990..62892
                     /locus_tag="VH957_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEQ8558248.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            62892..63707
                     /locus_tag="VH957_000304"
     CDS             62892..63707
                     /locus_tag="VH957_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEQ8558249.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMILSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFVDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(63806..65230)
                     /locus_tag="VH957_000305"
     CDS             complement(63806..65230)
                     /locus_tag="VH957_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8558250.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     GKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(65249..67111)
                     /locus_tag="VH957_000306"
     CDS             complement(65249..67111)
                     /locus_tag="VH957_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8558251.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGAATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            complement(67113..67955)
                     /locus_tag="VH957_000307"
     CDS             complement(67113..67955)
                     /locus_tag="VH957_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEQ8558252.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLIVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            68283..69650
                     /locus_tag="VH957_000308"
     CDS             68283..69650
                     /locus_tag="VH957_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8558253.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            complement(69704..71254)
                     /gene="ftsY"
                     /locus_tag="VH957_000309"
     CDS             complement(69704..71254)
                     /gene="ftsY"
                     /locus_tag="VH957_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEQ8558254.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEVVQQEDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHSSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KEVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(71254..72078)
                     /locus_tag="VH957_000310"
     CDS             complement(71254..72078)
                     /locus_tag="VH957_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8558255.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLINDESGVAEAVKTFILEEES"
     gene            complement(72082..72879)
                     /locus_tag="VH957_000311"
     CDS             complement(72082..72879)
                     /locus_tag="VH957_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8558256.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKVLANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            complement(73017..73331)
                     /locus_tag="VH957_000312"
     CDS             complement(73017..73331)
                     /locus_tag="VH957_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558257.1"
                     /translation="MTRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNGNL
                     SIDTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVR
                     ID"
     gene            complement(73397..73849)
                     /locus_tag="VH957_000313"
     CDS             complement(73397..73849)
                     /locus_tag="VH957_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8558258.1"
                     /translation="MGLLDLIGRKRARDKPQNSYEGQDFSYLFGRTISGENVDEFKTM
                     QTTAVYACVRILAEAVASLPIHIYERTENGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TIMSHLLIWGNAYVQIIRDKSGMVSLLLKQKASVLIRKLLLIIWQRMS"
     gene            complement(73954..74174)
                     /locus_tag="VH957_000314"
                     /pseudo
     CDS             complement(73954..74174)
                     /locus_tag="VH957_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(74193..74498)
                     /locus_tag="VH957_000315"
     CDS             complement(74193..74498)
                     /locus_tag="VH957_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8558259.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQGM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(74498..74800)
                     /locus_tag="VH957_000316"
     CDS             complement(74498..74800)
                     /locus_tag="VH957_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEQ8558260.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLSQLKENA"
     gene            74846..75940
                     /locus_tag="VH957_000317"
     CDS             74846..75940
                     /locus_tag="VH957_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558261.1"
                     /translation="MTQLKTQYPSLIIDASFITLAANATVKPQDKTYNTVNLLNRFFL
                     IWLDVASRGLSHHHVLSHPFKDWMTTMLDFPFHHEFIEFLGRWTHILITLLKRHHGQA
                     DTAIPRYLLVTIREKTGIVKSTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCD
                     RPLILTSGNLAAENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKIVTALKNVK
                     KILVSAHNSQQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTL
                     YQLVKNPVIDNYLTIQKIIVNLDKQGRIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTI
                     SEKLHKATLQDIYFCQMIVSYFIQKCEVLE"
     gene            75940..76164
                     /locus_tag="VH957_000318"
     CDS             75940..76164
                     /locus_tag="VH957_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558262.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            76155..77813
                     /locus_tag="VH957_000319"
     CDS             76155..77813
                     /locus_tag="VH957_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEQ8558263.1"
                     /translation="MLIEMWSPVFKNHGEIRESICFHYGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPNIILVCDKSYSP
                     TGETMDLGIFLNRLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYTFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDIEKNQQKLQLRNTKLELESSLRDKQRRLKLLDISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLETILDSEFSTERESLIAEIDEL
                     ESQLTTLNQELQELGNIPNLSSEYLESYSKLTATINALKEQNEAYLKESGLSKEKSEA
                     DADLKRSTEDILLDLEVKINSKMREFNNILYPDIRKAPQINLNAHNSYSFYTPDDDGT
                     GTKFKGMIVFDLVMLYLTNLPALTHDSLLLNNVSYQATEALLKLYDQSRSLNKQVFLA
                     FDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            77803..78012
                     /locus_tag="VH957_000320"
     CDS             77803..78012
                     /locus_tag="VH957_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8558264.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
BASE COUNT        23809 a        16634 c        13915 g        23728 t
ORIGIN      
        1 aaaaaagaaa tagagataat cgataaaaaa atcaatcgtc taaacgattt atatattaat
       61 gatttgattg acctaccaaa actaaaaaaa gacatcgaag aactcaatca tttaaaagat
      121 gattataaca aagcaattaa attgaattat ttagacaaga aaaacgaaga ctctcttgga
      181 atgctgatgg ataaccttga cattagaaaa tcttcgtatg atgttcaatc taggatagtt
      241 aagcaattga tagatagagt cgaggttact atggataaca tcgatattat ttttaagttt
      301 taaaagcatt atttaggcac tacaactagt atagttgtac atgccattat cggtctcctt
      361 tacaaacgtt attatccctt ttatcatatc acagaacatc agacacttca aaaaaacaat
      421 ggaaaacgac ttttagacag aaaaatcgta tgaacaaagg ctcatacgat aaaaatgttc
      481 tataagtcat ctgcaatttt attgatttta cgcaagcgat ggttgacccc gctcttggtg
      541 attgggaact caagggcatc agcaacttgt tgaatggaat agtctggatg cttaacccga
      601 agctgggcta cctgttgcaa ttcaatcggt aaactttcta aaccaattgt gtccatgatt
      661 ttaataatat tattaatggt tttcatgcta gcactgatag ttttggcaat attagctgtt
      721 tctgcattat tggcacggtt aatatcattt cgagcttctc gaagtaattt gatggcttca
      781 aagtcttctt tgcaggacat ggcaccaatt ataattaaaa agtccatgat atcttctgcc
      841 ttttgcaaat aagtaactgc accgctttta tgctcaatgg ttttggcatc tagcataaat
      901 ttttgcatga gttgagctaa atcttgagca tgatcaagat aaactgaata gatttctaac
      961 tgatacttgc ctgactcagg atctctgatg ctacctgccg ctagaaaagc ccctttaaga
     1021 taagaacggc cagcattatc gtctgataaa acctgaggtt cgatgcctgt ttccagatca
     1081 aaaaaggagt ccgctaattt caaatcggct aaaatggttt ccacaccttg ctcaacatag
     1141 acggtgtaaa cacggttttt gcgcaggttc gtcttttgat gatacctgat ttctggcacg
     1201 ataacatagg catcttcaat aaaagaataa atgtagcggg caattttagc attttcagtg
     1261 gtaatggata aatgaaggct ttggtgagct aagcccaagc tgcctgataa tttgatgatg
     1321 gcggccaatt cattgttgtc acctgtggac aagtgaatta attcctcttt gaccttggtt
     1381 gtaaaactca ttgcttgact atcctcacta aattcattaa ttcttccacc actaagttgc
     1441 catcgtgaaa agctccgcca ttctccaacc gtaaaaaata agacgaaatc acacgcttag
     1501 cagccctgca aaggccagca aagtcgtgat caacctgaac gaggtattca tcaaatttgt
     1561 tagaattcat gtaagcctgc ggcaccttag ccacatttac caaaaccgta tcaatcaaat
     1621 ctcttcctaa gtgctgattt aaaacagcca catggtctgc atctgaaaat tgttctgttt
     1681 caccatactg ggtcatgata ttacaaatat acaccacttc tgctttagtc tggcgcaaag
     1741 cttctttaat ttctggaatg accaaattag gtaaaataga ggtaaacagt gagcctggtc
     1801 ccaagacaat catgtcactt tctagaatag cctcaaccac cttacgactg gcctgaggct
     1861 tttggtcgtt gtaggtgttg gtcacataga catggtcaat catgccttgg tatttggcaa
     1921 tagaactttc tcctgctact tcatgcccat ctttaaaaac agcatgaagg gtcaaggcct
     1981 gctcgctaga ggggtaaatt ttacctgtaa tatggaaaaa tttggttaaa atttgaatgg
     2041 cattgtaggt tgagccttgc atttcagaga taccagcaat aatgagattg cctagagggt
     2101 gaccagccaa ggctccatca ttctcgttaa aacggtattg gaaaacccgc tcataaaatt
     2161 ttggcatgtc actcatcgct aacaagacat tccgtaagtc tcctggcggg gctaattgca
     2221 tggcattacg aagttctcct gaggaaccac catcatctgc aacagtgacc acagcagtaa
     2281 tatcaactgc ttcattacga aggcttttta ggataatgga gatgccagta cccccaccta
     2341 taacagtcat tttaggattt ttcatgaacg attcaccgtt tccttacgac gattttgatc
     2401 acgatggctt tcattaaccg accaatctgt tgccagactt tctgccaagc aatgggcaaa
     2461 ggcaacgctg cggtgttggc ctcctgtgca gccgatagcc accgtcaaga cagacttccc
     2521 ttctttttgg taagccggta agatagggac aataaggttt aacaaatgct tgtaaaacac
     2581 ctctgattct gggtgagaca tcacataatt aaaaacgtcc tcatctagtc ctgttttttc
     2641 acgaagctct acctgataat aaggattggg tagaaaacgc acatcaaaaa ccaaatccgc
     2701 atccaaagga agaccatatt tgaacccaaa gctcatcact tcaatacgga aagaggcttg
     2761 attagaccct tcagaaaact ggtctgaaat ggttttacgc aattgtctag gggtcaattt
     2821 tgttgtatcc accacatgtt ggctcatgct tttcaaagga gataggagtt ctctttccaa
     2881 tcgaatacca tcaagcacac gaccgtccgc agccaaaggg tggctccgtc tggtttcttt
     2941 atagcgtgac accaattctc catccgttgc atccaaaaaa agaatccgaa aatcaatgct
     3001 aggattgctt tcaatactat ctaaggtaga attaatttcc ttgaaaaaca aacgacttct
     3061 catatcgaca accaaagcca ccctacgatt ttcattggtt tgttcaatta attctaaaaa
     3121 ttttggaacc aaggctgggg gcatattatc aatggtaaag tagcctagat cctcaaaaga
     3181 ctgaatggca actgtttttc cagcgccgct cattcctgtc acaataacta aattaatgtg
     3241 tttgtctgac atttacaatt tccctttctc tatcgaaccg tccaccttca ttataccaca
     3301 tacataagaa agctaagaag tgaaaaagtg gtaacacatt ttgaactgta aaaatcagct
     3361 aattttaata ataactcccg tagctctcct attatatgaa tagacgagac ctttttagta
     3421 tcaaatgaga gtgtctattt gataatcgta gtccaaatac ttgtctataa aatatccctt
     3481 gagcaaggct atattgtctt atctgctaac tgatctacta aacttccaaa atttatcttc
     3541 acaaaggatg taggttcaaa ctctactatt tcttatctct cctttaggac atattgatgt
     3601 ttttataaca cactcacttc ttaccaatac aaaaagttca tagatgacat gaactttttt
     3661 gtattattag ggtctaatcc gatgtaacat acgtgggaat ggaatagctt cgcgaatatg
     3721 tttggtacca gcaacaaaag ttaccatacg ttcaatacct ataccaaaac cgccatgagg
     3781 aacagagcca tatttacgaa ggtcaaggta aaagtcatat tctgatttat ccatacctag
     3841 ttcatccatt ttagtcacaa gagcatcgta gttgtcttca cgcattgagc cgccaatgat
     3901 ctctccataa ccttctggag ctaaaagatc agcacaaaga acgcgttctg gatttccagg
     3961 aactggtttc atataaaatg ctttaaagct tgctgggtaa ttcactacaa atgtcggtac
     4021 tccaaagtaa ttagaaatcc aagtttcatg tggggaacca aagtcatcac catgctctaa
     4081 atgttcataa tctgtatctt catctgcttc atgctcttga agaagtgtaa tagcatcatc
     4141 ataagaaaca cgcttgaatg gctctgtgat ataacgtttg agagcctcaa catcacgttc
     4201 taaaatatca agtgcttgag gcgcacgatc tagaacgcct tggatcaatg ctttaacata
     4261 agcttcttga aggtcaagtg attcctcatg tgataagaaa gaatactcag catccatcat
     4321 ccaaaattct gttaaatggc gacgtgtttt agatttttca gcacgaaaga ctggaccaaa
     4381 gtcgaaaact cggcctagag ccattgctcc agcttcaagg tataattgac cagattggct
     4441 aagaaatgct ggtttcccaa aatagtctgt ttcgaataac tctgttgaat cttctgctgc
     4501 attttctgat aaaattgggc tatcaaattt gataaaacca ttttggtcaa agaattcata
     4561 agttgcataa ataatagcgt tacgaatttg cataacagcc atttgtttac gagaacgcaa
     4621 ccaaaggtga cggttgtcca tcaagaagtc tgtcccatgc tctttaggag ttataggata
     4681 ttcatgtgac tctccaatga tttcaaggtc agtaatatca agctcatagc caaatttaga
     4741 acgctcatcc tctttaacaa tccctgttac ataaacagat gtttcttgat tgagacgttt
     4801 aataacgtca aatttttcaa gacctgattc ttcaccatat ttttcaatga agtttggttt
     4861 aaaagcgaca ccttggaaaa aagcagaacc atcgcgcaac tgtacaaacg caatcttacc
     4921 tttacctgat ttgttagtaa cccaagcacc aatagtaact tcttgaccaa cataatcttt
     4981 aacatcaaca attgaaataa gtttttttga cataagtttc tctctatttt tatttaatta
     5041 atttcattac tttccataaa gacatgcagt ctacgaacag cttctttaag ggtttcgata
     5101 tctgtagcat aacttagacg aacattttcc ggtgcgccaa agcctgctcc actcacaaca
     5161 gctaatccga cttcctctaa aatagcattg gcaaagcttg tcacatcgga aaaacctgtc
     5221 atttccatgg ctttcttaac gtttggaaag aagtaaaaag ctccttgtgg tttaacaacc
     5281 tcaaacccag ggacctgaca caacaatgga taagtgatat taaggcgctc ttcaaatgct
     5341 aatcgcatct cttcaagtga tgactgacta ccacagaaag cctcgatagc agcatattgt
     5401 gaaacggttg tcaggttaga ggtagtctgc ccgatgatct tactcattgc cgaaatgatc
     5461 tctggttcac ctgctgcaaa accaacccgc cagcctgtca tggcataact tttagccacg
     5521 ccattgaccg taatggtttg acgacgaatc gcttctgaga gtgttgaaat aggaacaaac
     5581 tgattgccgt tatagactaa ggacccgtaa atatcatctg ccagaataag aatatcgttg
     5641 tgcaccgccc attctccaat ggcccttaat tcctcagcac cataaatcat gcctgttgga
     5701 ttggaaggag aattgataag gacaacttta gtcttacttg tccttgctct ttccagctgg
     5761 tcaacagtta ccttgaattg attttcttct agtccttgaa cgaagatcgg ctgaccttct
     5821 gccattttta cttggtcaga ataagatacc caatatggtg ttggaatgag aacttggtca
     5881 ccaggattta aaacagccat aaaaaaggca taaaggatga acttggcacc tgttcctgcc
     5941 acaatctgat caggagacaa gtgataccca tactgatttt tcagatatgt ggcaatcgca
     6001 gcttttaatt ctggaagccc agaagcattt gtataaaagc tagccgtacc attttgaata
     6061 gattcaatcg ccttgtcttg aatgtgctta ggtgtaaaaa aatctggttc tcctaaagtt
     6121 aaattcagta catcacggcc ctgcgctttc aaagccttag ctctagcacc tgcagccaga
     6181 gtaacactct ctttcatttc taaaactcgc tttgatagtt tgggcatcgt atctcctttt
     6241 tatcgacttc ttatcttcag attaattaat gatcaacaga tcattttttc ataatctacg
     6301 gtttcagttt taccaatact cgctactaat cgcacgaact atgacaagct gttttgatag
     6361 caactgacac taatgaaaag aacagtaatt gggtttacta aaaccaaaaa tttgttcatt
     6421 tattgtcctt atcaaaaaaa caattcgaaa acatttgaac agttgtctaa aagagcataa
     6481 taaaagttca aactaattta aatgttagtt gattgtgctt aacgccatta aaaatttttc
     6541 tgatataata gatcctttct attatatcaa aaaacagtcc gtttctacta gacaatcgtg
     6601 aaaattttgt tgagaaatca aaaattcctg accgagacct tccaaaataa cttgtccata
     6661 ggactttgta aggagacgac gatccaaaat aataaccact gacttttgat cttttcgacg
     6721 catcgtgcga ccaatagcct gttttaatcg caaaatagtc attggcaaga agtaatctct
     6781 gaaaggattt ttaccttttt ccaatagata atgactcatt ttcttaacaa agaaatcctc
     6841 tgggttatca aagggcaatc gtgcgataag ggtaatcata cgatccgctt gaataaaatc
     6901 aactccttcc caaaaagaac ctaaaccaag caaaatagtt tgctctcctt gatcaaaccg
     6961 ttttttaata ttataagctg ttccattctt ttcctgcgct aagtgaggca cctgccattg
     7021 gtctagatag tctgaaacca acagcaagtg ttttttagaa ttaaaaagca ctaaaatagg
     7081 ataaccctct tgcttcaagc tttcgattcg ttttgcaatt gcttccacat agatttggtc
     7141 actgacttct gtcacgatag gcgcctcttg atcaacaagc accaactggt cttgcttttt
     7201 atccttttca atgacatgat agagatactc ttcaaaacct aataggtctg ccaaggttac
     7261 ttctgagctg atggttaaag tggcagaaac aaaataagtt ttcaccgttt ctggtaagag
     7321 ctgttggaaa tgaataaatg ccttactagc actgtttaga taagtcactc gcttctcctc
     7381 ttgcttttcg ctactaagcc agtagtcacc atctgaggta gcaaaaaagg cttgtaactc
     7441 ttgataatct gctcctgtta attctttggc gtagccagct atacgagacc aatcatgagc
     7501 aagctggtgc tctttatttt gatagtaatc acttgacact tgtcccagtt caaacgacaa
     7561 gctttccaat aagcgttttt ctaaaagagg taaagggttg cttaacttgg cctgtattgt
     7621 ttgtaaaaaa accgtcaggt taagctgatg acgtgataat tgatctaatt ggagcatcag
     7681 cttttgggcc tcatcaaaga ccaagacctt gtttctagta aagtccttgt catcttgaac
     7741 acggtgtaaa aaataagcat ggttggtaat caggagacgg gctgttttgg ctttttcata
     7801 actaactctc caaaaatcat aatcgtaaaa ttcagaagac tgcttaatgt ctccatcgtg
     7861 cttaagctgc tcaaaataag cggcaaagcg ctgcttttgt ttgatttcgt caaggtctcc
     7921 tgtcttagtt tctaagagcc aaaccaataa ttgcatttta taacgattca ccaaacggtt
     7981 ctggtcattt tggtccaaac tatctgcaaa gctatctagc tttaggtaat tggcaggccc
     8041 ttttaaacta tggcaggcga tgtgaaattg ttcttgaata gcagctactt caccagccat
     8101 taattggtct tgaagaagtt tggttggcac actaacaatg atttggtttt gatcttcttt
     8161 tgccaaaagg ggtagcaggt agccgtaggt ttttccaata cctgtctgag cttcaataaa
     8221 actagctact ccctgatggt aatcttcgtc aattaactga gcaaattgag tctgtttagg
     8281 cctttcttcc agacctaata gtgccatatt aatagggaag ctttttgata tttgataagg
     8341 cttgagagct tttgagccct ttggtaagag aatctgtctg attttaatgt atttgttggg
     8401 atcataaggt ttggctttgg ctaatccttc ttgaatgacc attgctgttt caaacagcag
     8461 gctatctgaa tagactaata agctttctaa gcactcaatt ggaaggctct caattttttg
     8521 taaaagtctt aaaaacagta tagctgtagc tcttgcatct gcaatagcag tatgagcttc
     8581 tgccaaatca atattgagct gcctagatag gtgactaagg ttatactttt caaagcgagg
     8641 gaaaaatagt tgggctaatt caacagtatc aacacgtggt attgttaact catatccttc
     8701 caaaaaaaga gcttctgcca ataaatttgc atcgaacttt acattgtggg caacaaaaat
     8761 acaatcttca atcaattgat aaatgtgatg cgccacttga ccaaaatccg gagctttagc
     8821 caactgctta tccgtaatac ctgtcaaatg aacaatatgc tcatctaaag attcatgagg
     8881 attaacatct gtttcataac tatcaataat tttatttcct tggataataa caatcccaac
     8941 ctgaataata gaagcattgg gacctgctcc agtagcttcc aagtccacta ctgcatattt
     9001 tctaagtttt ttctggatca tagtaagtct attatagcac gctatatcta taaaacaaaa
     9061 catgactata tctcaaaggt gccatcactc caataaccaa gataggataa ttttttaaga
     9121 agtataaaaa acactgtgag tttcactcac agtgtcagca ttaatcattt ttaatggaat
     9181 accataccac catcgacaac tattgtttgt ccagtgatat aatttgaatc atctcccgct
     9241 aggaagccta ctgcattagc aacatcttct ggttcagaca agcgtttcaa agtgatatct
     9301 tttgcaaatt gctccatacc ccattcatca tctttgcctg catttttacc aacttcatgg
     9361 gcaatatcaa acatcatagg tgttttaaca atacctggtg cgtaagcatt gactgtgatt
     9421 ccttctgatg ccaaatcctt tgccaaagtc tgtgtaatac cacgaactgc aaattttgta
     9481 ccaccataaa cagtcaaatt aggattccct tcacatcctg cttgtgatgt tgcatttata
     9541 atttttccgc catgacctaa ttctctaaaa tgtttttgag ctgcttggct tccccaaatc
     9601 gttcctccga cattgattgc aaaagccttt tcaaactgct cttcagtaat cgtgtcaaga
     9661 ggggttgttg gggcaacacc tgcattgtta acaacaacat tcaaatcacc aaaagtatct
     9721 acaacttttt ggaaagcatc aaaaacttgg tcacgttttg aaacatctgc tacaactgca
     9781 acagcatcct caggtgatag tttatcaacc gcagcctgag cagtctcttc attatagtct
     9841 aaaatgccta ttttaaagcc gtctacatga agacgtttcg caatagcaaa tccaattcct
     9901 tgaccagcac cagtaacaat agcaactttt gacatatctt ccacctcata ttttttagtc
     9961 aaccgattag attgctctca aaaagtcagt gttcttaaac taagttcagc tttaggcttg
    10021 gcttattgat tacttttatg atacaccttt atgaaaacgg tgtcaagaaa ttgctgtgag
    10081 atctcatatt ttctgaaact aattgccatt tattttccgc tactcttttt ttaacaaagt
    10141 cttgattttt tggtacacta tccttatgaa aatctataaa acaataaacc acattgctgg
    10201 tgaaaatact tattacctcg ttaatgatca agctgttatc ctcattgatc caggaagtaa
    10261 cggccaagaa atcattgcta aaattaaatc ctttgaaaaa cctttagtgg ctatcctctt
    10321 aacgcatact cactatgatc atatttttag tttagatttg gtcagagatg cttttgatca
    10381 tccacctgtt tatgtttcag aaaaagaagc cgcttggcta tcttccccag atgataattt
    10441 atctgggtta ggccgtcatg atgatatcat taatgttata gcaagaccgg cagagaactt
    10501 ttttaaatta aagcaaccct atcaactaaa tggttttgaa ttcacagttt taccaacacc
    10561 tggtcattct tggggaggag tctcatttgt tttccactca gatgaattag tcgttactgg
    10621 cgatgctcta tttcgtgaaa ctatcggtcg tactgactta cctaccagta actttgagga
    10681 cctcattact ggtattcgcc aagaactatt caccttacct aatcattacc gagtttatcc
    10741 tgggcatggt ccttctacta ccatttgtca cgaaaaaaat gctaacccct tttttcattg
    10801 acatagctat tttagatact gtttgaggtt atcctaaaac tgaaatcata gtattttact
    10861 aaaaaagagc cactaaattt tgaatgacac cccaaaagtt agatacatca aacatctaac
    10921 ttttggggtg cttttcttct cttgaaacct tagaaactgc tattttaaac tgtattgcct
    10981 attacaaata aacaaatgaa tcaaaacaaa atgaaaagga ccagtcctgt gcaatacaaa
    11041 acgaggtcct tggaataata taagaggtcc aacttttgag ggtcgctacg tttcgtcagc
    11101 agcgcttttt ttagaatttt aaataacgtc tcatagaaag cactgaacca agcgaaccaa
    11161 tcataatacc tatgacaaac aaagcaccaa tcaggtaata tacataagga tcaagcggat
    11221 acatcgagag attattacgt tgtaattctt gtgcaaaatg cttataaaca agatcatatc
    11281 cataataaat cagaagagat ggtaaaacag ctcctaacaa gccaacccaa gccccttcaa
    11341 aaaagaaagg ccctcgaata taagaatttt tagcaccaac taaccgcata atttcaatgt
    11401 cgcgtttacg agacataata gtcatacgaa tagtgtttga aatgagaaag acagctacaa
    11461 ataatagcat tgctgttccg atcagccccc aagtttgaat taatgttgaa aacttaaata
    11521 gtttatcgga gttaatccct ccataatctg cggcttctac gccttcaatc gttctgatct
    11581 ttttagtgat cgccttaact tgtttaggcg tctgggtctc aataagatag atatcttgga
    11641 gcggattagt gtcttggtca tacatattcc aaacatcacc taaggtttct tgcaattttt
    11701 tcaattgttc atccttgcta gaaaatgtaa tctttttgac accttttatc tgagcaattt
    11761 tgtcgtaaac actgtggtag ttatcgttat taacaggttc accggcagta ttttgaataa
    11821 cttttgcagc atcagttgaa tcaacttgta agtaagtatt gatatggaca ttattttcaa
    11881 cacccgaagc aacacgctgt atattcaaca atgtcgccgc aaaaacacca actaaagtca
    11941 atgtaacagc caccatacta actgaagcaa atgtcatcca aaagttgcgt ttaagatttt
    12001 taatggattc ccaaatatga cggaaaaagt atctaatcat cgtaaccata atctcctttt
    12061 tcttcatcac gtactatgcg accatcttca atagcaacaa cacgatgacg gaatgtattc
    12121 acaatatgac tgttgtgtgt cgccattaag atagttgttc cctgaacatt aatacgttca
    12181 agtaactgca taatttccca tgaaatctca ggatctaaat tccctgtcgg ttcatctgca
    12241 atcaataatt tagggttgtt aacaatcgca cgcgcaatgg ccacacgttg ctgctcccct
    12301 cctgatagct gacttggaaa agaacgcatc ttatgtttca agccaactaa atcgagtacc
    12361 tctggcacgc gttttttaat gtggcggcgc ttttcaccaa taacttccat ggcgtaagct
    12421 acattttcaa agactgtttt tcttggtagc agtttgtaat cttgaaaaac tactccgatg
    12481 tgacgacgaa gaatcggaac atcacgtgct tttagtttag ttaaattgaa ttcacccaca
    12541 tatagcttac cagttgtcag ttgttcttca cggtaaagga gtttgataaa agttgattta
    12601 ccagcacctg atgggcctac gagataaaca aactcacctt ggttaacaga aacattgacg
    12661 tctctgaggg cggtcgttga gcggcggtat tttttagtaa caccagacat ttctattagt
    12721 gccatgtttc tcctttatta tttttagtct tcaatgcgcc acttaaggta ggcatcaata
    12781 aagccattga tttctccatc cataacctta tctacctgag caagctcaaa gttagtacga
    12841 tgatccttca ccatcgtata aggggtgaaa acataagaac gaatctgact tccccaagtg
    12901 atttcttttt tatcaccctt gagagcatct acttcttgtg ctttcttttc ttgttctaac
    12961 tgatatagct tagcctgcaa catcttcata gcgcgatcgc ggtttccata ttgagtacgg
    13021 tcaacggtag acgataccac aattccagtt ggaatatgcg tcaaacgaac acctgttgat
    13081 actttattga cattctgacc accagctcct ccggaacgga aagtatccat tttaatgtca
    13141 tcatcacgta cttctacttc aatcgtatca tctaactctg gcatcacttc aactgaagca
    13201 aatgaggtat gacgacgttt agccgaatca aaaggtgata tacgaacgag gcgatgaact
    13261 cccatttctg atttcaacaa accataagca ttaggacctt caaaagagag ggtaaccgat
    13321 ttaataccag cttcatctcc tgcttgataa tccaatactt ctactttgaa accattagca
    13381 ttgccaaaac gagtatacat tcgtaagagt aaatctcccc aatcttgcgc ttcagttcct
    13441 cctgaaccag gatggatttc taagatagca ttattgtggt catagggttc agataagaga
    13501 agcgtcattt cataagcacc cattatctta tctagctgca ttagattttc ttctaattct
    13561 tctttcaaag aatcatcttc gtcaagcatc tcaagtaaga gttctgtttc gtcagataat
    13621 tcttgcatat tatggaaagt atcatactta ccttttaact catttagttc ttgagatgtc
    13681 ttttgcgctg caatattgtc attccaaaag tctggctcag tcatgtgatt ttcaagaaga
    13741 gcaatctcct cttccaaacg atctaagtca aagagacctc ctgaagctag tcaacttctc
    13801 tttattttct actatttttt ggcgaatttc agccacttcc atgagatttc tccaatcttt
    13861 gttaatctgt tttattttat cataaggttc ttaaaaatac cataaaaggc ttaaacttgc
    13921 catttatgac ggattaattc caactctttt cggctatctt cattttttaa ggttaaatga
    13981 ctcataaacg ccagtatctc atcgtttggt tttttgacaa tttctcccaa tgcccatata
    14041 gctgttgcag tatgaatagg gttattattt ttatcaataa tctctattaa tttgaccact
    14101 gcggttttat catgagcatt tgctagcgca ataatggcat tacgctgtaa aatattttta
    14161 cctcgccaac ttccagcaat cataccaaat ttttctttaa attgtccatt tgataaactc
    14221 aaaaatggta ttaattctgg ttgagccaac tcaggatcaa tctctgtagc tggtgaattg
    14281 tttataccct tgttataagg acagcaaatt tggcaaatat cacaaccata gataactgtt
    14341 ttaatctttt ttcgaaactc tatgtccatc attcccttat cttgggtttg aaatgataga
    14401 caacgcttgg cattcattga gccatcacca attaaacaag aagttggaca ggcatctaga
    14461 caacgacgac agtcaccaca atcataatcg acaggcttgt ctggctcgat ctctaaattg
    14521 gtaattaatt ctcccaaaaa catataagag ccatattctt tagaaataac tagaccattt
    14581 tttcctataa aaccaatacc cgctctttgg gcaactgcag tatcaactaa agctccagta
    14641 tcgaccattg ctttttgttg caaaggaaaa tctcgacaca gctcttcaat gccttttgat
    14701 agtctgtcta acttttcgcc gaccacataa tgataatcaa gcccccacga actaggtgta
    14761 atttttccac gtttataagg tgttttttga ggttgctgag gaagtttgtg aggataagca
    14821 acgccaattg aaataatcgt tttagccgat tctaaatgcc tttcagggta gatacgatcc
    14881 tctatgactt tatgttcaaa tcctgaattg cgcccctctt ccacagaagc acgcaatgac
    14941 ttttccaaat aatcaaagtt atctgccgtc gtaaaaccaa ttttagagat accaatttct
    15001 ttggcgagtg ccttaatttc tgccttaata gtcatactac tatcataatc aaaataagtt
    15061 aagacttcaa ggaaaaagaa ggacaattct aatcaaacat aaccatttta cttcctgatt
    15121 tatttggggt ttctctctta acatgcacaa gaatgcaaca agtaaattca attacatcgt
    15181 aaaagtccct tttctggtta cctctacttg gtcagaaatc acatctccat cacgtcttgt
    15241 ctagacagtc agctcagctc taaagtaagt ctgactataa gcaatggacc tacgaagaca
    15301 agcagcataa cacttccaaa tattattata cctaaccaaa accgagtcac attacccgtg
    15361 caactcatgg actcagatac tgcctttgtc aaagcagtat tatgatcctt ctatatttac
    15421 tcactagcca atctaaaaac aaatccaaat aatgaccacg gttaaacata tctcctgcca
    15481 cataaagatg gtcaacgact aacgatcgca tccaaatcac aaaaatcata atccttttct
    15541 aggtgatctt atgcgacggt ttttttgata ataacttaaa catagtactc ttttcagtgt
    15601 catattgtaa ataggtagct aaaaaacagt aaaaacacat aaatatattc ttgttattgg
    15661 tctgtagaaa gtcctagacg tattcttaag tgtcttgaaa tatcatcaat gatcagttag
    15721 ttgtgttact tcacgatcca aaacaaccga tttttacaca cagttgtcct aaatgatcta
    15781 tcttgtgatc agcttgactc tgatcaatgc catatcggta gtcggtaatg gcaaaaactg
    15841 tcagattggc tgctttggcg gcagcaatgc ctttttggct gtcttctact acaagcagtt
    15901 gtttttttgt aatcctagtt tttgtactgc tttattatag atatctggat aaggtttgcc
    15961 tctagaaaca tcttcacgcg ctaggattat ttcaaaataa tcttttattt gcgttgtctc
    16021 caacgccaac aaaacatcct gacgcttcga gtttgatgcc acagccagtt taataccttg
    16081 ttttttcaac tgttcaagac aagagttcac ttctgtaatc aacagttttt gataaggagg
    16141 cttatgcgct tgtttgtaag cgtcatagtc agttgtaatt gccttaacga tagcatcatc
    16201 cctattttta cctaacaact ctttccataa ttcttgaaga ttgcccccaa taaaatcttt
    16261 agagttcaaa tgatcaatgg gaattccctt tgtcttaaaa aaatcttctc gtcgcctcag
    16321 ataaaaaggt tctgtatcaa ataaaacacc gtccatatca aaaataattc ctttaatcat
    16381 caacatttct ccttttttct attttagcat aagttgctgt aaaagctgta cagctagtcc
    16441 attctaagtg atatcacttt agatcaggtc catactaacg aattcaaaag gtattacttt
    16501 tgtttgatca taaaaagttt atatcctata tatcaaacga caggctcatc ttgttaaatt
    16561 agctgctctt atatctatat tatctggaaa aacataagca gaagcatatt aattgaatga
    16621 atgataaaaa aaacgttttt actagcacta aagccaaggt aaaaacgttt tttagattat
    16681 tgtcgcaaac ttttgatata atgagcggct ttcttagtga ttaggttata ttgtttttgg
    16741 ctcgctaact gattaaactc gcctcctatg cctagaacat ctactccagc agctagccag
    16801 tctttgagat tatctaaaga aatcccacct gtaaccataa cctctacttg tggcaaagga
    16861 gatttgattg cccgaataaa ggacatccct acagtagaac caggaaaaat tttgaccata
    16921 tcaacccctg attctaatgc tgtaaccact tcattaaccg tcatacaacc tggtaaataa
    16981 ggtatgctat aacgatgaca aatcaaagcc actgctcgat tgaaattagg accaacaata
    17041 aactgtgctc ctgctaaaat agcttggcgg gcagtgacat catccaaaac tgtcccagca
    17101 cctatcaaca cctcaggatc ttctttgaag cgttcagcta attgaccgat aacctcacta
    17161 gcaaaggggt tagtataggt gacttcaatt gtcttaatgc caccttcaat actggccagg
    17221 ctgcaagcta aagcttcctc actagactct cctcgtacaa ccaggacaag ccgattagcc
    17281 ttaagtttgg ttaagatttc tatttttccc atatcatcac ctctggacat ctcgttgatt
    17341 agctaagact gcttctactt gttggacgct gtgatagagc tgatcttcag ctactgtaca
    17401 ttttaggcta gctgttgcca cagcaaaatc aaggttgcgc tgcttttcgt taccttctaa
    17461 caactgataa agtaaacccg ccacaaaagc atctccactt ccaacccgtt gcaagactgg
    17521 ggtcgtcact tcacaggatt cgtaaaactg cccatcatag gcataagcct tgaaacgatt
    17581 actgccttgg gcatcatttg aacgctccgt atggtaaata gcttgtaact gatagcgctg
    17641 ataaagtcct gccagacgtt ctctaatcat cgtagcatct gccttattcc tatcaaacat
    17701 gtcaaaatcg tcactgtcta acagcaaagg ttccatgcca aaaataatat ccgcgtattg
    17761 agcaaagtgt gaaaagagtc gtttagcatc agctaccgca atcatactag atctaaagtt
    17821 aagatcaaaa gaaacacaaa tatccctttt cttagcttct ctcacaagta cctcaatcag
    17881 gtcctgagtt tttttgccca gtgccaaact gatcccacta aaatgaaagt gactaatgcc
    17941 ttcaaaaatg gcagctagat caagactatc cttatctaag gccgaaaagc tagagccaca
    18001 gcggtcataa taaacctgac tagaacgaca accaaagcca ttttcaaggt aatacagccc
    18061 aacacggttg ccctgccaag ccgtcaaggt catatccaca ccgctttgct tcaaaaactg
    18121 atgaaaagcg tgaccaacag gattatctgg tagggccgta aatagccttg cttctaagcc
    18181 aaaaccgcct agagttcttg caatattaac ttctgaaccg ccgaaaaaaa gctgagcgtc
    18241 gcaggcattg gtcaaaggct gaaactgatt gggactaacg cgtatcagcg gttcaccaac
    18301 caataataac ttagacatgt gatctccttt cctcgtcaaa atggaattac tgttcaagta
    18361 ctgatttcaa ataagtaact aattctgacg gctccgcatt ggcaaagaag tactctttaa
    18421 aatgagcgcc agaaatcgtt tctttgagga aatcttggtc gatgtctttg acaattgcca
    18481 acaaatctct gtaagtaatt tttttcagat cacttaaaat acgtgcattc cgctgttcag
    18541 gaatagctcg ccctttaggg taaccaccac ccattggttc tgcaaagagg cgttcaaata
    18601 ttaaggtcaa attcaactct gctccccaac caaaaccttt ggcaaaagga atggacaagg
    18661 cattaccacc attgatttga gaaaagagat aagcttctgt tggctcactc gcaaaaccac
    18721 aggtaacacc tgggaagctg ttcaaggcca acatagctcc aacacctgtc ccacaaccag
    18781 tcaccacaaa atcagccgcc ttagtggtca ataaaataga agctaagagt ccattttgaa
    18841 cataggtcaa ctggctttca ccttctgtgc catacatacc atagttaaag acttggtagc
    18901 cgtgtttatc tgtcactgtg gtaagggcat cgtaaatgat accattttta gccgcttggc
    18961 tattttcatt aattaatgca attttcatat aaaatctctt tctagtgtgt gattaaggtt
    19021 gttttccaat ataagctaaa atgccaccgt cgacataaag aatatggccg ttgacaaaat
    19081 tactggcatc gctagctaga aaaacagctg gaccagctaa gtcttctgtt gtcccccaac
    19141 gtgctgctgg tgttttagca atgataaatt gatcaaaagg atgacgacta ccatctgctt
    19201 gtcgctctct caacggagct gtttggggcg tcgcaatgta gccaggacca atcccattac
    19261 attgaatgtt ggcttctcca aactcagagg ctatattttt ggttaacatt ttcaagccac
    19321 ctttagccgc cgcgtaggca ctaactgttt cacgccccaa ttcgctcatc atagaacaga
    19381 tatttataat tttaccatgt ccctttgcaa tcattgatgg taatacagct tttgacacaa
    19441 taaaaggagc atttaaatca atatcaataa cttgacgaaa atcttctgcg gccatttcaa
    19501 gcatcggcgt acgtctaata atacctgcat tgttgaccag aatatcaata acacctactt
    19561 catcttcaat ttgactaacc atctgttgga taccagcttc atcagtcacg tcacaaacat
    19621 agccatgcgc ttctatccct aactctcgat aggcagccaa ccccttatca actaactctt
    19681 gtttgatgtc attaaacaca atagttgcac ccgcttgagc ataggctttg gcaatttcaa
    19741 aaccaatacc gtaggatgct ccggtaatca aggcaatctt accttgtaac gaaaacatat
    19801 tttccatagg attctccttt ttgttattaa attgagtaaa cctgtttact aagactataa
    19861 caaagtaaac tagttttgtc aagattttat gaaaacggtt caaaaataaa aaagagaaac
    19921 tagctagctt ttaaaaatag gttttattcc ttaatggcat ttcttttaca tagtgttctt
    19981 cattaaacaa ctatgattga tcccttttga catgttatgg agattaatct ctattttctc
    20041 taaaaataaa tctcaaaaaa gtattgacaa agaatcttga aagcgctaca atgtttttaa
    20101 gtaaaccggt aaactaaagg agatttattt atgattgcta ttatcgttat ggggcatgga
    20161 cattttgcga gtggtattgt ttcagcctta gaattgatcg caggcaaaca agaaaaggtc
    20221 actgctattg attttactgc tgagatgacc gccgctgatg tgcaggacca attatctcgt
    20281 gctttaatcc cagaagagga aaccttagtt ctttgtgacc ttctaggagg tacccctttt
    20341 aaagtcgctg caaccttaat ggaatctctt ccaaacacga cgtgtaatgt tctttctggc
    20401 cttaacttag ccatgctaat tgaagctagt tttgcaagac aaacagcagc ttcttttgac
    20461 gacttagtat taggacttat aacatgttct aaagaaggca ttgttgactg gaaaactctt
    20521 tctcagcaag aagacggtac gacagacgat gagttaggag gcatttaatg gcacgatctt
    20581 taaaaaccat tgctcttgaa cctatcaagc agcctgaacg atttaccaaa gaagatttcc
    20641 taagccaaga agacattact caggcccttg acttagccct caaacaagtt cggcttaata
    20701 tggactattt taaagaagac tttccaacgc cagctaccaa agataaccaa tatgccatta
    20761 tggataatac agaatggacc aatgcctttt ggacaggttg cctttggtta gcttacgaat
    20821 acagtggaga tgatgccatt aaagctctgg ctcaagcaaa tgacctttct ttcctagatc
    20881 gagtaacaag agacattgag ctagatcacc atgaccttgg ctttctttac accccttctt
    20941 gcatggctga gtggaaactt ttaaaaactt ctgaggctag agaagctgct ttgaaagcag
    21001 ctgacaaatt agtccaacgc tatcaagaca aaggcggctt tattcaagct tggggggtgc
    21061 tgggtaaaaa agaagattac cgtttaatca ttgattgtct cctaaacatc caattactct
    21121 tttttgctag ccaagaaact ggagacaacc gttaccgtga catggcgatc aatcatttct
    21181 acgcctcagc caatcatgtc atccgagatg acgcctctgc ttaccacacc ttctactttg
    21241 atccagaaac aggcgatcct gttaaagggg tcacccgaca aggttatagc gatgattcgg
    21301 cttgggccag agggcaagct tggggcattt atggtattcc tttgacctat cgtttcctaa
    21361 aagaacctga actcattcaa ctcttcaagg gcatgaccca ttatttcttg aaccgtcttc
    21421 ctaaagacca ggtgtcctac tgggatttaa tttttggaga tggtagcgag cagtctcgtg
    21481 atagttcagc aacagccatt gctgtgtgtg gtattcatga aatgttaaaa accttaccag
    21541 atcatgatca tgataaaaaa acatatgaag ctgccatgca cagcatgcta agagccttga
    21601 ttaaggatta tgctaacaaa gatctcaatc ctggcgctcc tctgctactt cacggagtct
    21661 attcttggca ctctggaaaa ggggttgacg agggaaatat ctggggagac tattactatc
    21721 ttgaagctct gcttcgtttc tacaaagact ggaaccctta ctggtaacaa acaccgatac
    21781 ctacatttaa aaaggagatt ttatgacaca accaaacatt atcatgacgc gagttgatga
    21841 gcgcttgatt cacggacagg ggcaattatg ggtcaaatac ctcaactgca acactgttat
    21901 cgtcgctaac gatgcggttt ctgaagataa gattcaacaa tccctcatga aaacagttat
    21961 cccatccagt attgccattc gttttttctc cattcaaaaa gtgattgaca tcattcataa
    22021 agcaagtcct gctcaaagta tcttcatcgt ggtcaaagat ttgcaagatg ccaaacacct
    22081 agttgaaggg ggtgttccca tcacagaaat caatatcggt aatattcata aaactgatga
    22141 taaggttgcg attacccagt ttatttcgct gggagaaaca gacaagtctg ctatttgttg
    22201 cttagcccat gaccaccaag tggtttttaa caccaaaaca actccagctg gcaatagcgc
    22261 ctctgacgtt gacatcttag attatattta atgaataaag gagattgata tggatatcaa
    22321 tttgttacag gcacttttaa ttggtctttg gacagccttt tgtttcagcg gaatgttact
    22381 tggcatctac accaaccgtt gtattattct gtcttttggt gtcgggatta tcttaggtga
    22441 cttgccaact gcacttagca tgggagctat ctccgaatta gcttatatgg gatttggagt
    22501 gggtgccggt ggtaccgttc ctcctaatcc tatcggccct ggtatctttg gtaccttgat
    22561 ggctattacc agtgctggta aagtcacccc agaagcggcc ctagccttat caacaccaat
    22621 cgcagttgcc atccaattcc ttcagacatt cgcctatacc gcttttgctg gggctcctga
    22681 aaccgctaaa aaacaattgc aaaaaggcaa tattagaggc ttcaaattcg ctgctaatgg
    22741 gaccatttgg tcttttgcta tccttggatt aggacttggt ttattaggtg ccttgtcaat
    22801 ggatactctc cttcacttag tggattatat cccacctgtc ttgctcaatg gattgactgt
    22861 cgctggtaaa atgttacctg ctatcggatt tgccatgatc ttatctgtta tggccaagaa
    22921 agaattgatt ccttttgtac taattggtta tgtttgtgca gcctacctcc aaattccaac
    22981 cattggtatc gctattattg gtatcatttt cgccttgaat gaattttaca acaaacctaa
    23041 acaagtcgat gcaacaactg tccaaggagg ccaacaagat gactggatct aataaattaa
    23101 ccaagaaaga ttacctcaaa acagctctga gagctttctt cctacaaaat gggtttaatt
    23161 acagtaatta ccaaggtatc ggatacgcca atgtcatcta tcctgccttg aaaaaacatt
    23221 ttggcagtga taaaaagggc ttatatcaag ctttagaaga taactgtgag ttttacaata
    23281 ctaaccctca cttccttcct ttcatcacca gtctgcactt ggtcatgtta gaaaatgatc
    23341 gtcctgaaga agaaacccga aacatcaaaa tggcacttat ggggccttta gctggtatcg
    23401 gtgactcctt atcacaattt tgcttggcgc cactcttttc aacgattgca gcttccttag
    23461 ctagtgatgg tttagtttta ggtccaattt tcttcttcct agccatgaat attatcctaa
    23521 ctgctattaa aatcggttct ggtctctatg gctataaagt cggcacaagc tttattgata
    23581 aattaagtga acaaatggcg gttgtgtcgc gcatggcaaa tattgtcggt gttaccgtta
    23641 tcgctggatt agctgctact tctgttaaaa taactgttcc cattactttt gcggctggca
    23701 aggtggatgc ggccaataca gcacaaaaat ttgtgactat tcaaggaatg cttgataaaa
    23761 ttgctcctgc acttttacca gctctcttta ccttactcat gtattacctt attaaaaaca
    23821 aaaaatggac aacctacaaa ttggttctcc tcactgttct tatcggtatt atcggtagct
    23881 ggttaggtat tttagcttaa tggttcacag agacctgtta tgagcatagg gaaatagttc
    23941 ctaagcacat gatgaggtct cttttctttt ggaaaggaaa tgtcctatgt ctcttgcctt
    24001 cacacgcttt aaagaaacag tcaatccaga cttttgcagg aattacctgc tagactatca
    24061 ggctgacagc tatgctgatc gaaaaaggat agctgaccta ctcttaacca ataccttttt
    24121 atttgaagat aattgggata tggagccctg ccacatccct taccacttag atcccattac
    24181 ttggcaaaag gctgtcacag atgatcctga gtggaatttt atgttaaatc gacagaccta
    24241 tctccaaaca ttaatcctcg tctaccttgt tgaaagagat gaacggtatc tcctaaaagc
    24301 caaaagtttc atcctcaatt ggattgaatc agctattcct ttagacccta aggggttagc
    24361 tactagaacc ttagatactg gcatccgttg ttttgcttgg gtcaaatgtt tgatttacct
    24421 taatcttttt aacgccttaa ccaaacaaga ggaaagcctc atcctagctt ccctggaaaa
    24481 acaacttcaa tttctccata ccaactacct tgataaatac agcctcagca attggggaat
    24541 cttgcaaacc actgcgattt tattagctga tgcctacttt ggttccgacc ttgatattgc
    24601 tgcagcaaca gctttcgcta gaaaagaatt gacgcaacaa atcgcactcc aaattctcga
    24661 agacggtagt caatttgaac aatcaaccat gtatcatgtg gaagtactca aagcccttct
    24721 ggaattaact gctctagtcc ctgattatct tccacagctt agacctactt tgcttgccat
    24781 gagtgattat ctcctcaaaa tgactggtcc tgaccacaaa cagatcccct tgggagatag
    24841 tgattttacc gataccagag acattctaac actagcagcc actatccttg aagaaccaca
    24901 cttaaaagct gctgcttttc ccgcacttga tatcgatagt cttctccttc taggagaaaa
    24961 aggtgtccac acttttgaac agttacccgt ccaaacctta ccaacttttg cgcatcactt
    25021 tgaacattcc gggcacatta ccatcaatca agaaaattat tatctttttt tcaaaaatgg
    25081 gcccatcggt agttcccata cccatagcga ccaaaatagt atctgtctct attataaagg
    25141 acaaccactt ttctgtgatg ctgggcgata cacttacaaa gaagaaccat tacgctatgc
    25201 cctaaaaagc gctagccatc attctaccgc cttcttagaa gaacaattac ctgagcagat
    25261 taatagctcc tgggcttacc tttcttaccc caaatccaat tattgtcacc ttcgacaaaa
    25321 tggacacgtt tactttattg aaggtagcta ccagacgcaa ttctctgata ggaacaacta
    25381 ccaacatgac cgacaaattc tcatcttacc accaggaatg tttcttatca ttgatacgat
    25441 acaggctcaa ggcaaccact gtcttgtcag tcaatttatt cttgataatc acttagaagt
    25501 aaagacagat caccttagtg acctcagact aatcagtgac tgccctttca ctatcgaaga
    25561 aacgattttg tcaaaaaaat acaaccaata cctgactagt cacaaactca tcaaacgaaa
    25621 accctttaaa gacaagggtt gcaccagtac cctattagtc cctgacgata ccaaagttac
    25681 tcccttaaca ccacttcaaa caggcaaacg caacccaatt gagaccgctc ttgcttggca
    25741 tttaaaagga aagcagtttg actacagtat ctgcgttctc caagaggact taattaaagg
    25801 agaaaaacta gttctcctaa atggtcataa aattagagga aaggtggttg ttatcaacca
    25861 tatcacgaat gagattattc gattgaaaca ctaaatcttt tacgagtcct tatgttataa
    25921 tatgactaac cattactaaa ttaaaggagt gtatgcaatg cagcgcaaag taaccatcaa
    25981 agatattgct gaattggcta aaacttccaa aacgacagtt tccttttact tgaacggtaa
    26041 atttgacaag atgtcagaag aaactaaaaa tcgcattaaa agcacgattg aagctaccaa
    26101 ctataaacca agcattgctg ccagaagtct caatgcaaaa tcaactaaac tcattggcgt
    26161 ggttattggt gatattacca atagtttttc caatcaaatt gttaaaggca ttgaaagcaa
    26221 agcccaggaa tttggttacc aaattatcat cggaaacagc aactacgacc cttctcgcga
    26281 agatgaactc attgaaaaga tgctgaacct cggagtggat ggctttatca ttcagcctac
    26341 ctctaatttc aggaaatatt ctcgcattat cgatattaag aagaaaaaag tggtcttttt
    26401 tgatagccaa ctttacgaac atcgcacaaa ctgggtcaaa actaataatt atgatgctgt
    26461 ttatgatacc attcaacaat gtatcgataa aggttatgaa cattttatca tgatcacggg
    26521 taaccccaat ttacttagca ctcgtattga acgcgcttcg ggcttcattg atgtgttaga
    26581 agctaatcat cttactcatc aagaaatgat tattgatgaa aatcagactt cttcagaggc
    26641 aattgctcag tttttgcaag gatcactgac taaaaagagt ttggtttttg tccccaattg
    26701 ttgggctctt ccaaaagtat ttacagctat gaagtctctt aaatttaata taccagagat
    26761 tggactagta ggatttgata acattgagtg gacaaaattt tcttcaccaa cactaacaac
    26821 tattatccaa cccgcctatg aagaaggcga acaggctact aagattttaa tcgatgatat
    26881 tgaaggtcac agtcaagaag ccaaacaaca aatttttgac tgtcaagtca attggcaaga
    26941 atcaactttt taatgtcagg cataccaata gtccttatcg ttgtaacgat tataaaaaaa
    27001 ggtttgagac aattgtctca aaccttttag cgtctattaa attgcttttt catcttgacc
    27061 aagtgatcgt tgaacagctt tgacaagctc aacaagaaca accatcaaga gacttccgat
    27121 aataaccact aaccattgtg tgatcgtcaa gtgtgtcaca tggaagaatt gattaaatcc
    27181 aggaacaaca actgttgcca tcaatgctac aaaggccact ggaatagaat agttgaacaa
    27241 tttgtttttg aacaacccaa cagtaaagat ggattggtaa acagatttca cgttgtaggc
    27301 atgtaccaac tgaatcaaac cgagggtcac ataagccatg gtcaaagcat ctgcatgaac
    27361 atcatggtag cttgtgtgtt ctgggaacat caaggcaaaa ccataaaccc caagaaccag
    27421 catggtttgg aaggcacctt ggtaaagaat ggcttccttc accccaccat caaagaagct
    27481 tgacttacgt ccacgaggtt tatgcttcat cacaccaggc tcagcaggtt caacaccaag
    27541 agcaatagct ggtagggtat ccgttaccaa gttaatccaa agcaagtgaa ctggttgaag
    27601 cacatcccaa ccaaacaagg ttgcaaggaa gatggtaaag acttctgcca tgttagcaga
    27661 aagtaaatat tgaattgttt tttgaatatt tgagaagacc ttacgtcctt cttcaaccgc
    27721 aacgataatg gttgcaaagt tatcatcggc aagaaccatg tcagaagctc ccttagaaac
    27781 ctctgtacct gtaattccca taccaatacc aatatctgcc gttttaagag atggtgcatc
    27841 gttaacccca tcgccagtca tggcaacaac tttgccttca ttttgccaag ccttaacgat
    27901 acgaacttta tgctcaggag atacacgggc atacacggag tattgtttaa agactttttg
    27961 gaactcttca tctgataatt cgttgagttc agcacctgta aagacatgat caacgccatc
    28021 ttcttcgata ataccaagac gtttcgcaat agcttttgct gtatcttggt ggtcaccagt
    28081 aatcatgatt ggacgaatgc cagcttcctt agctacttta acagcctgtg ctgcttcagg
    28141 acgttcaggg tcaatcatcc ctaccaaacc agagaagaca agattagcct caacaatttc
    28201 tgtttccagt gttggaagag catcagaata tttgtaagcc atcatcaaga cacgaagagc
    28261 ttgtttggca agactcttat tggtatcaag aatggttttt ttatcagcat ccgtaatagg
    28321 acgaatttgt ccattttctt caatctgtgt gacacgcttc aacaattggt ctggcgcacc
    28381 tttaacagcg atgaaatatt tgccatcagc ttgtttatga atggttgaca tcaacttacg
    28441 gtcagaatca aatggtaatt ctgccacacg aggttctgcc accatagcct cacgtacgtc
    28501 aaaattgtgg tctaacccaa actgtaccaa agctgtttct gttgggtcac caattaactt
    28561 ccctgaagga tcaactttag tatcattagc aaagttcatt acacgaagtg tcgtattgtc
    28621 aaaagcaata tcagctgatg aactttggag tgtcccgttg gtataaactt tttcaacggt
    28681 catttgattc attgtcaagg tacccgtttt atcagaagca atgatttcag ttgatcctag
    28741 cgtttcaaca gctggtaatt tacggataat ggcgttacgt ttagcaagta cttgagttcc
    28801 aagagaaagc acaacagtaa caatcgcagg aagtccctct ggaatagctg caacggcaag
    28861 cgctactgaa gtcatcaagc cttcaagcgg gtgttgacca cgcaagaaga ctccaacagc
    28921 aaaagtcacc gctgcaatca caaggatcgc ataagtcaaa atcttagaaa ggttgtcaag
    28981 gttttgcttc aatggtgtat ctgtctcatc agcattagca agcataccag caatatgccc
    29041 aacctcggtg tacatgccag tgttagtgat aaccccaatc ccacgaccat atgtcacatt
    29101 tgagttttga tatcccatat tgacgcgatc accaataccg gcatcttctg aaacagccgt
    29161 tgacaagtct ttttcaaccg gtacagattc tccagtaagc gctgcttctt cgatttttaa
    29221 ggagttagct tccaaaagac gcagatcagc agggacaaca tctcccgctt ctagcaagac
    29281 aatatctcca gggaccaatt ctttagagtc tatctcagtc acatgcccat cacggcgaat
    29341 acgagccagt ggacttgaca ttgatttcaa ggcttcaata gcagcttcag cttgtccttc
    29401 ttggtaaaca ccaaaagcag catttaggat aacaacagcc aagataataa tggcgtctgt
    29461 caaaccttcc atcccctctg taagaactga aagaagggct gccacaatca aaataataat
    29521 catcaaatcc ttaaattgat caaggaattt cataaataaa cttcgttttt cgccttcatc
    29581 aagctcatta cgaccatact ctgctaagcg ctcttttgct tgggcagacg taagaccttc
    29641 gcgactggtc tctaattgag ccagtacggt ctcttcactt tgcgtgtaaa acgcttcatg
    29701 tctttgttct ttagacaaat tagtacctcc ttggtctttt tattttagtt attcaaataa
    29761 aaagacctgt ttattttctt aaacaagtct cgctgtttaa gattgtaccg gaaaccgaaa
    29821 ttccgtattg acgatacaat cacggctagc cgtctgctac tcccttgata taataaccat
    29881 tatagtaaaa acctgactaa aaaacaagaa taatccctaa tcagatgatt tactgctatc
    29941 tttttagtta atcccaactc agctcaagat gatagcttgc aaatagcatt tctgtttgag
    30001 cttgaagcaa atgataatga aggtccaatt tttgacaaga acaatctaag tggtaatgac
    30061 tggtatctgt caaaaattgt tgaaccccca tcggcgtagg tagagcaatc aggaccttct
    30121 tgcccgcaaa aaatttcatg attgactgag ggttggaaaa acggctcatg gtcagttctg
    30181 tctcattgta cttgatgaca accttttcct tgtcagtgtt ttgatagatg aggtactgat
    30241 agcccccttt ttctcgccac tcacaatcat gaatttcttg aataatctct gtctcatctc
    30301 caaagcgaat atggttggtt aactgtaatt tcataactct tctttctatt ctaagctcgt
    30361 ctgtttattc tatcaatttc tccttatttt atcaattttt gatataataa aaattatgaa
    30421 tgaaaaagta tttcgtgacc ctgttcacaa ctatatccac attgataatc cattaattta
    30481 tgaccttatc aataccaaag aattccaacg cttacgacgc atcaaacaag tccctacaac
    30541 agctttcacc ttccacggcg cagaacatag ccgtttttct cactgcctag gtgtttacga
    30601 aattgcccgt cgggtgacag ctatttttga agagaaatac gctgatatct ggaataaaga
    30661 tgaaagtctg gtcactatga cggctgccct cttacatgac attggtcatg gagcctattc
    30721 tcataccttt gaggctcttt ttcatacgga tcacgaggcc tttactcagg agataattac
    30781 caatcctgag acagaaatca atgccatttt ggtgcgtcat gctcctgatt ttccagacaa
    30841 agttgccagc gtgattaatc atacttatcc taacaagcaa gttgtgcaac tgatttccag
    30901 ccagattgac tgcgaccgta tggattacct tttaagagat tcttattttt ctgctgccaa
    30961 ttacggtcag tttgatttaa tgcgtatcct acgtgtgatt cgacctgttg aagatggcat
    31021 tgtctttgaa catagtggta tgcatgctgt cgaggactat attgtcagtc gttttcaaat
    31081 gtacatgcag gtctattttc atcccgccag ccgtgctgtt gagctcatct tacaaaatct
    31141 cctcaaaaga gcccaacact tatatcctga gcaacaggct tatttccaaa aaacagctcc
    31201 tggactcatc cccttctttg aaaagaaggc taatttagca gattatatag ccctagatga
    31261 cggagtcatg aatacttact tccaagtctg gatggcaagc gaagaccata tcttatcaga
    31321 tttggccagt cgctttatta atcgaaaaat tctgaagtct gttacctttg accaagattc
    31381 ccgaggagag ttagaacgct tgcgccaatt ggtcgaatca gttggctttg atccagatta
    31441 ttacaccggt atccatatca acttcgacct gccttatgat atttatcgac cagagctcga
    31501 aaatccaaga actcagattg aaatgatgca aaaagacggg agccttgctg aattatctca
    31561 gttatctcct attgtcaaag cattaacagg gacaacctac ggagaccgtc gcttttattt
    31621 tccaaaggaa atgttagagc tcgatgacct ctttgctcct agcaaggaaa cttttatgag
    31681 ttatatttcc aatgggcatt ttcactttag tcagtaaagc cctttaagat tgcagaaaaa
    31741 gtcttttttg atacttttct taggtggcac ttatggcagc gagttccttt ggaattctat
    31801 gctttatttt tgagcctagg gtctcaaaaa tcccgcgtaa cgtcactgcc agtattgaca
    31861 ccacttttgc cacagcaaaa agcagctgtt ttggctcacg tcacacgcag aaataagaaa
    31921 tcagttgtca aatcagcaga gcagttcatg ctttttgagc atcaaactgg gtttgtctcc
    31981 attctaagat tgaagaaaga gtactttctt caatcttttt agttactaca gaggcgattg
    32041 agctaaacta aaacgttttc tctcgttttt ccttaagttt cctttcccat cccatgacaa
    32101 aagcacctat ttttagtaag ataggaggga gaacattttt aagataaacc acaaaaaaac
    32161 aaggaggatg ccatgtctat caaactggtt gctgtcgata ttgatggcac attactcact
    32221 gatgaccgtc gaattacaga tgatgttttt caagctgtcc aagaggctaa agcccaaggt
    32281 gttcatgtgg tgattgctac tggcagacct attgccggag tgatttcatt actcgaacaa
    32341 ttagaactca accacaaagg aaaccacgtt atcactttta atggtggctt ggtgcaagat
    32401 gccgagaccg gcgaagaaat tgttaaagaa ttgatgactt acgacgatta tctggaaacg
    32461 gaatttttga gccgaaaatt aggagttcac atgcatgcca ttaccaaaga aggtatttac
    32521 actgccaatc ggaatattgg aaaatacaca gttcatgaat cgactttggt aaacatgcct
    32581 attttctatc gcactcccga agaaatgacc aataaagaaa tcatcaaaat gatgatgatt
    32641 gatgaacctg accttttgga cgcggccatc aagcaaattc ctcaacattt ctttgataag
    32701 tacaccatcg tcaagtcaac ccctttttat ttagagttca tgccaaaaac cgtcagcaag
    32761 ggtaatgcca tcaaacactt agctaaaaaa ctcgggctag atatgtcaca aaccatggcc
    32821 atcggggatg ctgaaaatga tcgtgctatg ttagaagtcg ttgccaaccc tgttgtcatg
    32881 gaaaatgggg ttcctgaatt gaaaaaaata gccaaataca tcaccaaatc caacaatgac
    32941 agtggtgtgg cacatgctat tcgcaagtgg gtattaaact aatgtataca tataaaatcg
    33001 gaatatctcc tgaagaacat gatcagtttg tcttagcaca gccacaagct ggcttacttc
    33061 aaagttcaaa gtggggaaaa gtcaaagata actggaaaca tgaacgcatc agcttttatg
    33121 aaaatggggt acaagttgct gctgctgctt gtttaatcag aaaacttcct cttggtttca
    33181 ctatgattta tatcccacgt gggccaatca tggactacgc caattttgaa ctccttgatt
    33241 tcgttattaa aacgctcaaa actttcggaa aaagcaaacg agcgcttttt gtcaaaattg
    33301 atccaagttt agtcatcaaa caaactttag aaggaaaaga aagcaaagaa aatgatgtga
    33361 cactctctat tattgctttt ctaaaaaaac ttggtgtcga atggtctggc agaacaaaag
    33421 aactcgaaga cactattcaa ccaagaatac aagccaacat ctacgccaag gattttgact
    33481 ttgacagcct gcccaaaaaa gccaagcaat ccattcgtac cgctaccaat aaaggtgtta
    33541 atgtcacgat tggtggcagt gaattgctag acgacttttc agccttgatg aaaaaaaccg
    33601 agaatcgaaa aggcattatc cttcgaggca aatcctatta tcaaaaatta ctaggtattt
    33661 atgctggtca gtcctacatt actatggcta gtttagactt acctgaacaa aaaaaactct
    33721 tgatccaaca gttggacaag gccttagcag aacaagcacg attaacagat aagagtaaac
    33781 ctagcaaagt agcagaaaat caaaaaacca ttgcacggct acaaaaagat ttaaccattt
    33841 taagcgagca gctcgctgca ggcaaaaccc gcatcccact agccgccacc ctaaccttga
    33901 tttatggcga gacttctgaa aatctttatg cgggaatgga cgatgattat cgcaattatc
    33961 aagctcctct tttaacctgg tatgaaacgg ctaaagaagc ttttaaaaga ggctgccgct
    34021 ggcataattt aggaggtgtg gaaaatcaac aagatggtgg actctatcat ttcaaagcta
    34081 gactcaaccc caccatcgaa gaatttgcag gtgaattcaa cattcctgtc ggccttgttt
    34141 caagcttagc catcttgacc tataacttaa gaaaaaaatt aaggagcaca actaatggca
    34201 ctaattgaaa tttcacaaga acaatttgac cattactgcc acagtctcgt ccatcattcc
    34261 tttatccaaa cctcagaaat ggccagcttg atggctaaaa gaggggcaaa accacaattt
    34321 cttggacttg aaaaagatgg tgaactaaag gttgctgcta tggtctttag ccaaaaagtg
    34381 gctggaggtt ggcgtatgga actcaatgca ggccctaata ccaatcatcc cgaagaatta
    34441 gaacattttt acactcaact taaagactat gccaaacaaa aagacgttat cgaactcatt
    34501 ttaaaacctt acgacaatta tcagtcattt gatactgatg gcatccctat ttctcatcca
    34561 aacactgacc ttattagcct tttaacggcg ttaggatata aacatgacgg tttaaaaaca
    34621 ggctatcctg agggtgaacc tgtttggcat tacgttaaaa agttagaagg aattgattcc
    34681 tcacgtttaa cccattcctt cagcaaaaaa ggaaaagctt taataaaaaa agctaatact
    34741 tttggtatta aattacgtca actgaaacga gatgagttac accatttcaa agaaatcact
    34801 gaagcaacct ctgatcgtag agattacctt gacaaatcat tatcttacta tcaggacttt
    34861 tatgatagtt ttggagactc ttgtgaattt atggttgcga ctcttaattt tgaagattac
    34921 cttaataacc ttaaacaaag acaactacaa ctagcaacca gcatcaacaa agttaaagga
    34981 gaccttggca aaaatcctca ttctgaaaaa aagcaaaata gattaaaaga actatccagc
    35041 caattcgaaa cctttcaggt aagaatttct gaagctctcc attttcttga agagtatgga
    35101 actaaagatg tgttccttgc gggaagtctt tttatctata ccgaacaaga ggccgtctac
    35161 ctcttttcag gatcttaccc caaatttaat aaattttata gcccagctct attacaagag
    35221 catgctatgc tcaaggcaat tcataagggc atcaaacaat ataattttct tggtattact
    35281 ggaaagtttg atggttcaga cggtgtcttg cgctttaaac agaatttcaa tggctttatt
    35341 ttgcaaaaac cagggacatt tagatgttat ccatttccaa tcaaatatca tttcattaga
    35401 ttggcaaaaa agctattaaa ccgctattaa gctaatgcat ttacctgtag aatcaccttt
    35461 attctctcat agtaagagtt aagtcatcta aaaaagaaaa ggatttaacc ttttcttttt
    35521 tagatgactt agttaaggaa atcaagcaaa gcaaggaagc tatcagcttc aagtgatgcg
    35581 ccacctacaa gggcaccgtc aacatctgga caagccatgt aatctttaac gttttcaggt
    35641 tttacagaac caccgtattg aacgcgaact ttatcagcaa cttcttgccc aaagtctgct
    35701 gctaccacgt cacgaacagc tttacacatg ttttgagcat catcttgagt agctgattta
    35761 ccagtaccga tagcccagat tggctcataa gctaaaacaa gtgaagctac ttgctctgct
    35821 gaaagacctg caagtgctgc tgaaacttgc gcacctacaa actcaacggc tttaccagct
    35881 tcataagttt caagagactc accacaacaa acaattggag ttaaaccgtt agcaaagatt
    35941 gctttggctt ttttattaat gtcttcatct gtttcatgga agtaatcacg gcgttctgag
    36001 tgaccaatca caacatagtc agctcccatt tcagcaagca cttttggtga tgtttcacca
    36061 gtgaatgccc ctgtgttttc aaagtagcag ttttgtgcag caactttaag aactgaatct
    36121 ttagcagctt caatagtggt taccaaatca acagctgggg ctgctacggc aacatcaaca
    36181 aggtcagttg aaggtaattt gcttgctaca gcctcaacga atgcttttgc ttcttgaggg
    36241 tttttgttca ttttccagtt accagcaata attggtttac gtgacatatc acatacctct
    36301 tcttttttta tttatatctt ctattttagc acaaatgacc gacgattaaa aggaattgct
    36361 tatattttag gaatattttc acaaataaaa actctttttc tgaaagcttt tcattcttat
    36421 ttatcagcat tttatggagt ttaagatagc aaaaagcccc cgaattgggg gcttcttcaa
    36481 acttaagttg tctgacttaa attgctattc tgggaactta attaaaatta agcttcgatt
    36541 tctgaaacga tacctgaacc aacagtacgt ccaccttcac gaattgagaa agtagtacct
    36601 tgttctacgg cgattgggtg gatcaactca acgttgattg ttacgttatc accaggcata
    36661 accatttctg tacctgctgg aagttcgatt gaacctgtta cgtcagttgt acggaagtag
    36721 aattgtggac ggtagttgtt gaagaatgga gtgtgacgtc caccttcgtc tttagaaagg
    36781 atatatactt cacctttgaa tttagtgtgt gggttgattg aacctggttt agcaataact
    36841 tgaccacgtt cgatttcgtc acgttgaaca ccacgaagaa ggatacctac gttgtctcct
    36901 gcaagacctt cgtcaagttg tttacggaac atttcaacac cagtaacaac agctttttta
    36961 gtttcttctt tgataccaac gatttcgatt tcgtcgttga cacgaacagt accacggtcg
    37021 atacgtcctg aagcaactgt accacgacct gtaattgaga atacatcttc gactggaaga
    37081 agcaatggtt tgtcagtgtc gcgttctggt tctggaatgt atgaatcaac agtatccatc
    37141 aattccatga tgatgtcttc aaatttagtg tcgccttcaa gagctttaag agctgaacct
    37201 tggataacgg gaaggtcatc acctgggaaa tcgtattctg aaagaaggtc acgaatttcc
    37261 atctcaacta attcaagcaa ctcttcgtca tcaacaaggt caactttgtt catgaacacg
    37321 ataaggtgtt taacaccaac ctgacgtgaa agaaggatgt gctcacgcgt ttgtggcatt
    37381 ggtccatctg ttgaagcaac tacaaggata gctccgtcca tttgagcggc accagtgatc
    37441 atgtttttaa cgtagtccgc gtgtcctgga gcgtcgatgt gcgcatagtg acgagttgca
    37501 gtttcgtact caacgtgtgc agtgttgata gtgattccgc gttcgcgttc ttctggagca
    37561 gcatcgatag aagcgtaatc ttttggttgg ttaactgatg aaggcaagcg acgtgccaat
    37621 acagttgtga ttgcagctgt taaagtagtt ttaccatggt caacgtgtcc gattgtacca
    37681 atgttaacgt ggggtttact acgatcgtat ttttcttttg ccattttagg aaaagcctcc
    37741 aataaaatat attttataga tagacggtag gccatacagt ctaactttac cttactattg
    37801 tagcaaatta caatgaaaat gcaagtattt tatgtttttt gccatttctt tattttttaa
    37861 atagaagaaa aagtcttttt tgatactctc cttaggtggt gcttatagca gcgacttcct
    37921 ttggaattcc acaccttatt tttgccacag caaaaagcag ctgtttgggc tcatgtcaca
    37981 cgcaaaaata agaaatcagc agagcagttc aagttttttg agcatcaaac tgggattgtc
    38041 tatattctaa aatctcctta aaggagattt tagaatatta ttgaaattgc ttgatattta
    38101 caactttact attttctttt cgagtgtcct ttcgataaga taattcagct tctttaaata
    38161 tatcatctcg cttttcgcta gcatcaatat ttagtacaaa acccactgca acagataaga
    38221 caagtaagct atttccacct tgagacaaaa aagggaaggt aacaccagta gatggaatta
    38281 agcctgagat accaccaata ttaacaaaga cttgcatgag catcataccg cctactccta
    38341 aagccatcat ggcattaaaa ggattttttg ctttaatacc aacattcata atacgtaaaa
    38401 ttaagaagaa aacaagtgcc aaaataaacc ctgctcctat tagacctaac tcttcaatga
    38461 caactgaaaa gacaaagtct gtctgtgctt cgggcaaata gccacgcttt tcaatggaat
    38521 ttcctaaccc ttggccaaac cacccaccat tactcatagc atagtaagaa ttggctaatt
    38581 ggtgacctga atcggtcaag tcatgaaaag gattaaaaaa ggcactaaaa cgtttagcga
    38641 catagccaaa aacaggaatc ttagcaactc tttctacccc aataacggca atagtcccaa
    38701 gaaagaccgt ggatagaccg gtaatcatgg ctaggatagc cgaaaaccat cggtaaccaa
    38761 tgccactgat agaaaacata ataatggctg tcaatacaat aatggaagca tttcctaagt
    38821 caggctgagc agcaaccaaa agtaccatca acaaagaata aacacgccag tcccgtaaat
    38881 cgttccattg tgttggccac cattttcgac gagttagtgc ttgataatca taaaggctaa
    38941 tgtttttttg gatcttagca aaggtcagtg ccaaatacca taccataatg atctttaaat
    39001 actcagcagg ctgaaagctg actggtccga tcacaatcca accatgcgct cctttgatag
    39061 cagttgtaaa gaagcgggca ataattaaaa gaaaggcctc tcctaacata accacagtta
    39121 atacccttgt attcgttaaa aaatttaatt ttaatttata gataaatgta atagccacta
    39181 gacttattat ccaaaaaact ccctggttaa tcaccgattt aaatggatta gcatgtgctt
    39241 gaatcaagct gacacttgtg gttgagtaaa ccattattaa gcctatcacc gataaaatta
    39301 aataaggcaa taatatagaa taatttaaga ggtgcctttt atcaatcttc atagttttcc
    39361 ctctacttct tgagataatc atttagcatt ataacatctt tctatatcaa acaaaaggaa
    39421 aagtcaagaa tcctcaaaaa aagaagctcc aagggctaac ctttaaaatt ctgattagtc
    39481 acttgaaaac ttctataaat accaattaat actcaagagt attagcctga attacgtaaa
    39541 ccagttgcta tgccattgat agttgtatgg atcaattttt catcattttc gtcaagttga
    39601 ttattacgcc aacgtttaat caattcaatt tgaatatagt tcaacacatt aaaatacggc
    39661 aagcgtgact tcaagctatg cttaagggaa ggattatcct ccaatagatc atcatggtct
    39721 tggatagcaa gaataacatt ttttgtcaat tgccactcat ccaaaatctc ataaaaaaca
    39781 tctcgaacat cctgactttc ggctagttgt gcatactgaa aggcaatatt catgtttgat
    39841 ttagataata ccatatcaac atttgataac aaggaatgga aaaaaggcca cgtctgatac
    39901 atgtgttgga ggcgttcaag gttaccttgt gctcggtcaa tataacgttt aaaggctgaa
    39961 cctaccccat accaacctgg gaacatgatg cgattttgtg accatgaaaa gacccaagga
    40021 atggcacgca agcctgtaat ttccgtaatc gttttacggg ctgctggtct tgacccaatg
    40081 ttgagactgg aaacttcctt aatcgggctt gcctcaaaga aataatcata gaaatgggga
    40141 ttgtcaaaaa ccaattttcg ataaatggtg ttgctatcag caacaatgct atccatgatt
    40201 tctcgaaaac tatcaatctc attaggatct gttatcattt gagtcaccat acgattgata
    40261 gaagctgaaa tcaacatttc taaatggtaa taagccacat ctttattgcc gtatttgttt
    40321 tcaataattt ccccttgctc tgtcagacga atccgatctt tgatggaacc aaaaggttgt
    40381 gaagtaatgg catcataaga agggccacct cctcgaccaa ctgttcctcc acgaccatgg
    40441 aagaaggtga ttttcactcc atgttcctca ccaatagccg ttaattcatt ctgagcttta
    40501 taaagagtcc aacccgatgc caagtagcca ccatctttat tactgtcaga ataacctaac
    40561 atgatttctt ggtaattacg attcgttgca atccaagatt tgacaatgtc atggcttaaa
    40621 taggctgcca tgatgtcacg ggcattatct aaatcctcaa tggtttcaaa gaggggaaca
    40681 atttgcacac gagcccgctg ctggtcaacc aatcccactt ctttaagcat gatggccaac
    40741 tcaaacatat cagagacact ttctgtatgt gaaataatat gttgcttaat aacctcttct
    40801 ccaagcttat ctttcaattc tcgtgccgta gtatagatag ccagttcttt ttctaatagg
    40861 tctgatttag caactgccgc tgaggataag gttcttggct cctccattaa ttgttgtaag
    40921 agaacatcgc atttttcagt ttctgaaaga gagctataat cgtcaacaat attggctcct
    40981 tttaataact ctgccacaca agcttcttgg acactggagt cttgcctcat gtcaatgctt
    41041 gctaagaaga agccaaaaat atcaacagct tgcatgactt ctcgcaaatc cccctcaatc
    41101 aaagcggagt tgccattatc aagtagcgac tgctcaatag cctttaaatc agctttaaaa
    41161 tcaacaggag agtcataggc taagatgggt ttttctaaac tagctggtga gggccaagca
    41221 gatgtgttta gtcccacact actattcata cgagctgctg gctgattagt tagttgaatt
    41281 tgtgtttgtt taagacgcga ttgaatataa tgaaaagctc tgcgataagg ttcatttcca
    41341 cggtaaatcg attggtcctg agacaaactg gctaaacgtt ccacttccga gttgggttgt
    41401 accaaggttg acgacagtga aaatgttcgg taaagggctg ctaatttgtc aatgtagtaa
    41461 ttgaggataa cctcactttg aaccgtagct gacaagcaca aggtttcagc tgtgacaaag
    41521 gggttgccat cacggtcccc accaatccac atccccatgg taatgggttt gggattgtct
    41581 aactctagac cgtgtttttg ggctaagttt ttgtactctg ttgtcaactt ggtcactgct
    41641 tgaatgagag aaccatcgta atactgcatg acatttttta tctcgttttt cacctgaagc
    41701 tttttctcgc gaataatatc tgtctgcatg atcatttcaa tataacgata tagctcctga
    41761 cgccatttct caagattaat cacaccagcc ttagcatcac ggtatttgcg cagaagttta
    41821 tgaatgtgag ttgtcaattc cagaatcgtt ttacgttgta cttgcgtcgg atgtgctgtt
    41881 aaaacaggaa ccacattaac ctgctccaaa atgtctttac cattatcttt tccagcaaga
    41941 tccttgatgg ttagggctaa ttttcctaaa taatcagtat ccgtattatt ttgatgatta
    42001 atttcatagg ctaaatcgac atcttctgaa atattgatta gcaagggtaa aatagaaaaa
    42061 tacctggaaa tcacttccat ttcttgattt gaaatattgg cgacaacttt ttctaattct
    42121 atgtaatctt gtttttcaga taacaccata atagactcga taactgtaaa cgcatcatct
    42181 ccaatcatcc gtcgtgtgat attttccaac atttctttca aaagagcaac ttcttcagca
    42241 atgatagttt gattgttact actctctaac tttttaagtg gcaaatgacc atctccttct
    42301 ttgctagttt cttctatcat accacttttt accaaaaata aaagtgagca tgttcataac
    42361 gtttgttttt taacaaaagt aagcgcttta tttcaaaaaa tgtttggata ggtttagtct
    42421 ccatattcca ctaaaattct gttatactag tcttgactat attgttaagg agacaactat
    42481 ggaattgaaa aaacgttcag aattccctga aaatgaactt tgggatctaa cagcgctcta
    42541 caaagaccgc caagattttt tactcgctat tgaagaatcc ttacaagata ttgacctgtt
    42601 taagcgcaat tatgaagacc gcttaacatc ggtggacgat ttcactcagg ccttaataga
    42661 aattgagcat atttatattc aaatgagtca tattggcact tatgccttta tgcctcaaac
    42721 cactgacttt tcagatgaaa gttttgctca aattgctcag gctggcgatg atttcatgac
    42781 taaagctagc gttgccctta gcttctttga caccgcctta gccaatgccg accttgacgt
    42841 gttagataca ttagaaaaga acccttattt cagcgcagct attcgcatgg caaaaatcca
    42901 aaaagaacac ctcttaagtc ctgatgtgga aaaggctttg gctaacttac gcgaggttat
    42961 caatgcgccc tatgatattt acaccaaaat gcgggctggt gactttgaca tggatgattt
    43021 tgaggtggat ggtaaaacct ataaaaatag ctttgtttct tacgaaaatt tctatcaaaa
    43081 tcacgaaaat gctgaaattc gtgacaaagc tttccgttcc ttctcaaaag gtctccgtaa
    43141 acaccaaaat actgctgctg ctgcttattt ggccaaggtt aaatctgaaa aattgttagc
    43201 tgatatgaaa ggctacactt ctgtctttga ttacctccta gctgaacagg aagtggatcg
    43261 tagcttgttc gaccgccaaa ttgacctcat catgactgaa tttggaccgg ttgctcagaa
    43321 attcttaaaa catgtcgccc aagtcaatgg tcttgagaaa atgacttttg ctgactggaa
    43381 gctagatatt gacaatgatc tcaatccaga agtcagcatt gatggtgcct atgacctcgt
    43441 gatgaagtct ttagccccat taggacaaga atacacgaaa gaaatcgaac gttatcagac
    43501 agaacgctgg gttgactttg ctgctaatgc caataaagat tctggtggtt atgccgctga
    43561 tccttacaag gtccatccgt atgtcttaat gagctggact ggcagaatgt ctgatgtcta
    43621 cacgctcatt catgaaatcg gacactctgg ccaatttatt ttctctgata atcaccaaag
    43681 ttacttcaac acccatatgt caacttatta cgtcgaagcg ccatcgacct ttaatgaatt
    43741 gatgcttagt gattacttgg aacatcagtt tgatgaccct cgtcaaaaac gttttgctct
    43801 tgctcaccgt ttaacagaca cctactttca taacttcatc actcacctat tggaagcggc
    43861 tttccaacgt aaggtttaca ccctgattga agaaggcggt acctttggag ctgaccaatt
    43921 aaatgcaatg atgaaagagg tcttaacaga cttctgggga gatgccgttg acattgacga
    43981 tgacgcagct cttacctgga tgcgccaagc gcattactac atgggcttat atagttatac
    44041 ctattctgct gggcttgtta tgtcaacagc tggttacctt aaccttaaaa acaacccaga
    44101 tggggcaaaa gaatggcttg acttcctaaa atcaggtggc agccgtacgc cttttgatac
    44161 tgcaatgctc attggggcag acattgccac cgaaaagcct cttcgagata ccattcaatt
    44221 cttgagtaat accgttgacc aaattatcaa ttacaccgag gagatgtcac atgcctaatc
    44281 tctatgattt tacggttaag gctcaaaacg ggaatgacct ttccttagct gcttataaaa
    44341 aaaaggttgt tttgattgtt aacacagcta ccaagtgtgg attaacccca caataccagg
    44401 ccctgcaagc actatatgac acataccatg acaagggatt tgaggtctta gattttcctt
    44461 gcaaccaatt tttaaatcaa gctccaggag atgctgagga gattaatcac ttttgcagtc
    44521 tgacctatca cactactttc cctcgctttg ctaaaatcaa agtgaatggt aaagacgctg
    44581 atcctttgtt tgcctggtta aaagaagaaa aaagtggtcc ccttgggaaa cgcatcgaat
    44641 ggaatttcac taaatttctc attgaccaaa atggtcaagt cattaaacgc tattcctcaa
    44701 agacagatcc taaactaatt gaagaagacc ttaaagcact tcttggttaa tataaaatag
    44761 acttggcgtg ccaagtctat tttatattat agttactatt taaaaacttc ttgataaaat
    44821 tcaatgctat caccatcttt aacggtaatt tgatcgacac ccttatctgc catctttcca
    44881 ttgaccttaa aaagccagta tttgttagct ttcgtgtctt gctcgatacc atcaattgct
    44941 gtgataaaac catctttttc tttaacctca taattatctt tgagaatctc aagcaccgta
    45001 tctccttttc caaaagaaac tttttcatca atggtattgg tatcttcttt gacaactaag
    45061 cgaacgtgat ggtctgcttt tggaacgctt ggagtcgtct gtatttgttt tgttccttgc
    45121 gagcaagcaa caagtagcat agcaacaagt gctagaaatc ctgttttaaa tcttttgttc
    45181 accgattaac ctcctaaata acatcatcac aactggaaaa aagacgagag ttgataaagc
    45241 atgcgctata ttaaagggca tccctgctaa aacatagctc caccaaggca tactatataa
    45301 atacgcaaaa caagtatcta tcagcacccc ataaaggagg ccacataagg cgaccaagaa
    45361 agcctgacag ccaagctgat atttggggaa ttgctgagac aaagggtaca agacaaaacg
    45421 ccataacaaa agaacaagca caaaacaagt aacttgccaa aagacccaag ggccaaatcc
    45481 cagcaaaaag gctgataaaa acaagcacaa catcataact aatacagcct cggctaaccc
    45541 aaagtaaaga agataactga gtaaaaatgc cgtcacaggc tgcacgttag gcaggctgct
    45601 aaaaaccatt ctcaacacaa cacatagggc tgacatgata gcaatgcgac tcataagctt
    45661 agctgacata aacttcttcc tcgttttttt ctctattatg acagatttac aaagcgttta
    45721 ccagtttgga gctcacttat ttatcaaatg ataataacat gagaattaaa taacaaaaca
    45781 gtacttgctg actgtcatga tatagtcaaa gactaaacta atattgtaaa gaatatagct
    45841 accaactata agagatagtg acataaactt gacatagtta gagaggatct catttgtaac
    45901 ttctcaaaga gaatacctta aaatgcaaga caatataaga aaacagttag gatattttga
    45961 ttttttttag taattagggt acaataacag ttaatgagaa gaaaaataaa acctattgtt
    46021 gtgctagtct tctttatttt actggcaatg gtattgatta tcggaaaaag acaagctaat
    46081 catgcgaaac aaaaagaagt tgaagacgct aagagtcata ttcctattgc aaccagtaat
    46141 cctagtaaag caaaagctag cacttctgaa accgaagact ttattttaaa tcctattgtt
    46201 gatgtttccg gctggcaact ccctgaagaa attgattatg acacattgtc acgtcacatc
    46261 tctggcgcaa ttgtacgtgt ctatggagga tcgcaaatta cagctcataa caacgctgct
    46321 tttacaactg gaattgacaa atcttttaca acgcatatca aagaatttca aaaacgaaat
    46381 gttcctgtag ctgtttacag ttacgcactt ggtcgtagta ctaaagagat gaaagaagag
    46441 gcccgagctt tctacaaaaa cgctgctccc tataatccaa cttactactg gattgatgtc
    46501 gaagaagcca ctatgaaaga tatgaataaa ggcgtaacag ccttccgaga agagcttaaa
    46561 aaacttggtg ctgaaaatgt tggtctctat attggaactt attttatggc agaacaagat
    46621 atttcaacaa aaggtttcga tgctgtatgg attccgactt atggtagtga ttctggctat
    46681 tatgaggctg ctcctaatac aaccttagat tacgatttac accaatatac ctcacaaggt
    46741 tatctcagtg gttttaacaa tgctttagat ttaaatcaaa ttgccgtaac aaaagacact
    46801 aaaaaaacgt ttgagaagtt atttggcaac tccaacaatt aagaggttag catcatggct
    46861 aatctttttt gtagtttaca tcttaccaag aaaaactcta ggtcaataat ttaacccccc
    46921 ttatccttga caaggagatt atctcatcat ataatgaaag cactataata tttcacaaag
    46981 gagtgctttg gctgagatcg caattgcgaa atcctgagga cctgatcttg ttagtacaag
    47041 cgtagggatt gtgaccaata atcaatgatt ggaaagcgat actctttttg tgcacaaaag
    47101 gagtttttta tgtcaccaaa caccaatgtc aaatacctta tcgaagctgc tatttttgct
    47161 gcattggcga tggccctttc atttattcca gattttgctg gctggtttag tccttcttat
    47221 ggtgctattg cactggttat tttctctttg cgccgtgggt taaagtacgg catgttggcg
    47281 ggtctcattt gggggctgct tcactttgta cttggaaaag tttactatct cagcatgtcc
    47341 caagtcttta ttgaatatat cttagccttt acctctatgg gattagccgg tagtttctct
    47401 gatagtttga ttaaaacttt aagaagacaa caaacctttt ttgccgtttt tcttgcaata
    47461 atggctagtt tactagccgt tacagtacgt tacttgtggc acttccttgc aggaatcatt
    47521 ttctggggca gttacgcccc taaaggcatg tccgctgtct ggtattcttt tagcgttaat
    47581 ggtacagctg gtgtcctaac ttttttaata acatgtttag cgttaatgat tgctttacca
    47641 attcatcctc aattatttga tcccaaagac taatttttag tcatttgaat cttacattaa
    47701 aaaaatggta taataatgtt gttataccat ttttttatgt ttagataaag gtaaggactt
    47761 gatatggcta aaaaaacaaa actcaaaaaa accttagtag aacaaatcct cgataaggct
    47821 aatattgctc atcaaggact caagcttaat gctttagaag gcgactttcc agatgacctt
    47881 caaccatcag atatttacaa gacacttgct ctgactggtg atcaaacagg tcctctaatt
    47941 ggcattattc cattaacaga acacttatca gaaaaacaat tggcaaaagt atcaggtaac
    48001 aaaaaagtgt ccatggttcc tcaaaaagac ttgcaaaaga caacaggcta tattcacggt
    48061 gccaataatc ctgttgggat tcgtcaaaaa cattcatatc ctatttttat tgaccaaact
    48121 gcactggaaa aaggtcaaat aatcgtttca gctggtgaag ttgggcgttc tataaagatt
    48181 tctagccagg ctctagctga tttcgttggc gcaagctttg ctgatttaaa gaagagaaaa
    48241 tgaacactac tgccaacttt atctggtttc ttttttaagt ttttcgcctt gattaagcta
    48301 gtctttgttt agtattattt tgatctcaac tgctttaaca ttgatcctgt taatcttttt
    48361 cttgtgtaaa ggcttgatat cacgacaaat tcaggtcgat ttgtcttaaa tctaatatgg
    48421 gctttacact ttaatcagaa cctagctatt atacacttat actacgcttt tttactttat
    48481 cttttcacta taggtattat ttttgcttgg tgatgcctaa actttttctg gttacttttt
    48541 tatttttagc gctcgcatca gttatttcta aaaggaggct taaatgaaat tatattttgt
    48601 aagacatggg aaaacccttt ggaatttaga aggtcgcttt caaggcgctg ggggcgattc
    48661 gccattactt gaagaggcaa aagacgaaat tcacttactt ggcaaagagt tagctaaggt
    48721 ggcttttgat gccgtttata ctagcgacct tcaaagagct atggcaacag cagctattat
    48781 cttagatgct tttgaccaac agccaaaact ttaccacacc gaccagcttc gggagtggag
    48841 attaggtaaa ttggaagggg ctaaaatagc aacaatggca gctatatatc cccaacaaat
    48901 gctggctttt cgggagaatc tagcccagtt caaaccagat cagttcgagg ctgaatcaat
    48961 ttaccaaacg acccaacgtg tctgccatct tatccaatcg tttaaagata aacattatca
    49021 aaacgttctt attgtaggac acggcgctaa cttaacagca actattcgct cattattagg
    49081 ttttgaacct gctcttttac tcgctaaagg tggcttagat aataccagtc ttactattct
    49141 tgaaactaag gattatttaa cttatgactg tttaatttgg aatgataaat cttttctaga
    49201 ggtgtaaaac cactagacaa taataaaaaa agctaacaca ttgatctctt actgacaaga
    49261 cactcacttt gctagctttt tttattatta tctagtgggc tattatggtt tcatctatct
    49321 ggcatatttt aagcgcaaaa ctttttcttg ctgcttggtt aatcgaagca agataaccac
    49381 tttgtcaatg ctcatgttgc tttcaagtaa acgctctgct gccatcatca agccattatt
    49441 gattcccatc tgtaaaattg gatttttctt gtcattgaca tcaaaaataa atttattatc
    49501 aggtaaatca aagagtactt taacggcacc aaagagctgt tcaaagttat caatagccgc
    49561 atcataaaca ggcttagttc ctggttttag ctgacgacct ctatgattaa accacataga
    49621 atgccaacca ccattaaagg cacccatgat atcattgtca taagagtccc caacatatag
    49681 tgtggtttgt gggttcatgt caaattgttc tgctgccagg ttaaaaattt ctttttctgg
    49741 tttttgaaag cctgttgctt ggctcacaat gacacgctta ggatcaatat aatcataaag
    49801 ccctaattta cgaacttttt tcagctgatg ttctgtgggc ccattggtaa taatccccat
    49861 aggaacattc tttgatttta aaaagtcaag ggtcatacgc atctcatcta acatggtaat
    49921 gttctcaagt tcgtgctcat agacttcttg aaaatgtact cccgcagctt cgtcgatttc
    49981 tcgatagcca aactcaagca gtgtttcctt gcaacgccaa aatcggaaat attctgtggt
    50041 ccactcccct gccattactc ttgggaatcc aacatctgaa tagtgacgaa agcgaatata
    50101 agcttgattc attactgaca tatcaaaatc tgggaagcac ttttccatgg cgattcgata
    50161 aggcgcttgc tggtcgtaaa ttgtgtcatc cacatcaaaa acaatagcag taatcatgag
    50221 tctcttttct tttctagttt aatatcccaa tcattatact attttccatt aggcttttca
    50281 attttatttt caaaaaagtg ccccgctgca gtcgcatttt ccaacgaaat ataggtgtat
    50341 tctagcctct tttatgatac aatggaaagg aaatcgtatt ggaggaaaat atgtctaatc
    50401 aacacatcga agaattaaat gaccaacaga ttgtccgtcg tgaaaagatg atggctctgg
    50461 ctgaacaagg aattgatcct ttcggtaaac gctttgaccg cacagccaat tctgctgaat
    50521 taaaagaaaa gtatgctgat aaaacaaaag aagaattaca tgagttaaac gaaacagcta
    50581 ttgttgctgg ccgcttgatg acaaaacgtg gcaaaggtaa ggttggtttt gctcatcttc
    50641 aagaccgtga aggccaaatc caactttatg ttcgcaagga ctctgttggc gaagacaact
    50701 atgaaatctt caaaaaagcc gatttaggcg actttatcgg cgttgaaggc gaagtcatgc
    50761 gtacagacat gggcgagttg tcaatcaagg caaccaagtt gactcacctt tctaaatcac
    50821 ttcgtcctct tcctgaaaaa ttccacggat taactgatat tgaaaccatt taccgtaagc
    50881 gtcaccttga tttaatttca aatcgtgaga gctttgaccg cttcgtgacc cgttccaaaa
    50941 tgatttcaga aatccgtcgt tatttagacg gtcttgattt cctagaagta gaaacgcctg
    51001 tgcttcataa cgaggctggt ggtgctgctg ctcgtccttt cgttactcac cataatgctc
    51061 aaaacattga tatggtgctt cgtatcgcaa cagaacttca tttgaaacgt ttgattgttg
    51121 gtggtatgga acgtgtctat gaaattggtc gtatcttccg taacgaggga atggatgcta
    51181 ctcataatcc tgagttcact tctattgagg tttaccaagc ctatgcagac tatcttgata
    51241 tcatgaacct gacagaaggc attatccaac atgctgctaa agctgttaaa ggtgatgggc
    51301 ctattgatta tcaaggaact gaaatccgta tcaatgaacc tttcaaacgt gtccacatgg
    51361 tagatgctat caaggaagtg acaggtgttg atttctggcc tgaaatgact gtcgaagaag
    51421 ctattgcact tgccaaagaa aaacaggtcc cactcgaaaa atacttcaca agtgtcggac
    51481 atatcatcaa tgctttcttc gaagaattcg ttgaagaaac cttggtccaa ccaacctttg
    51541 tctttggtca tcctgttgaa gtatcacctt tggctaagaa gaatccagaa gatacccgct
    51601 tcaccgaccg cttcgaactt ttcatcatga ccaaagaata cgccaatgct ttcacagagt
    51661 taaatgatcc cattgaccaa ttatctcgtt ttgaagcaca agcacaagct aaagaacttg
    51721 gtgatgacga agcaactggc attgactacg acttcgttga agctcttgaa tatggtatgc
    51781 cgccaaccgg tggactcgga atcgggattg atcgtctttg catgttatta acaaacacaa
    51841 caacaatcag agatgtgctt ttattcccaa caatgaaacc ttaacttttt taagatttgt
    51901 attcatatct taaaaccgat aagtggcaat ataacataac gttttattat ctctaaccag
    51961 tcttcattac catgaagact ggtttattaa cagtagctta tagaaagtga cttaacaaga
    52021 tgaccaaaga atatatctcc tacattagtg ctgctatctt cttgctttat ggccttttag
    52081 ctgccaaatg gatttttctt gggctaggct taattttggt acttgtcggc cttgctgacc
    52141 gcctcaattc aaaaaaataa tccttctatt cgctcctgtc cttttaacct agcgatgtca
    52201 tcaccaggtt aaaaggacag gggcgaacga gggattatgt ttcgtttaag gtaacattac
    52261 ttacgaaaag cgtctaagat ggttttaaat tcttcattag taagagtaat gcctttcccc
    52321 attttcgtat ggtctggact ccacgtgcgg atatcccatt tcgcttctgc gccattaaag
    52381 ctgacgcggt tcaattcttt tgtccaacct ttatcatttt ctgataaggt gagtaaatgt
    52441 tcctcaatgt tgaatgtaaa ttctgccatt agttttcctc ctcatctata ctattcgaaa
    52501 ttaaagtgga aaaaatcatc tttttttcac ttttttttat gactcattct cctattattc
    52561 tatcaagttt tgagaaaata agctattgtg atatccaact ttcaaaaaaa aacaggctct
    52621 cttttcccaa ctatggtcgt ataccatttg gaaaaagagg gcctctagta tttcttgtta
    52681 ttatgttcta acagttttac tggtgccatc tttttgatag aggttgacaa gaccttcctt
    52741 gcaagcccta atcatatccc ctggcttaac ttctctcggt aaagagatgg ttaagagttc
    52801 cattggattt ggggcacggt caatcttttg gccatccgca tcatgtaagt ccttaacaac
    52861 cgtttcaaaa tgacggaaac ctggtccata acattcaatc cgatcgcctt ccatgatgac
    52921 attacgctga cgaatggtcg ctgtcatgct ggctgagtca aaggcaacta cttctccgac
    52981 aaatttatat tgtggaattt tgcggcgagc accaaataat tgttcatttt cagttgggat
    53041 accatagtaa aaacctgtag ccaactcgcg ctgggcaacc ttccacaact cgtcaatcaa
    53101 ttcctctttg atagcataaa aagcttctgg gctttccatg taagcatcta cagccgcctt
    53161 gtaacagttg gttacggttg agacgtagtg gatagatttc attcggcctt caatttttaa
    53221 gctatcaacc ccattttcaa tcaggtcagg aatatggtca atcatacaca tgtcaacaga
    53281 ggacatagaa tagtcttctg gaatttcccc ttttaaggag cggcgctctc ctccaaatgg
    53341 catgtcatac aaatcatact tccagcggca agactgtgag cagccgcccc tgttggcatc
    53401 acggtgactc atgtggtttg acaaaacaca gcggcctgaa taagagatac acatggctcc
    53461 atggacaaag gcttcaattt ccacatctgt ccgcttacgg atttctgcta actcggccat
    53521 attaacctca cgagctaaaa caactcgggt caaacccatg gctttccaaa attcaaaggt
    53581 ctcgtaattg gtagatgaag cttgcgttga caaatgaatt tccaaacctg gggcttctgt
    53641 tgaacaaata acaatcaagg ctggatctga aacaatgacc gcatcaagcc ccatatcacg
    53701 cagttgacga aaccactcgc ccgcaccaat ttcgttccct tcgtgggtaa ccatgttggc
    53761 agcaacatag accttagctc cacgcgcatg tgcataatca atgccttctt gcaattcttc
    53821 catagagaag ttaccagcgc ggcttcttag gccataggcc tgtcctccaa caaaaacagc
    53881 atctgcgcca tagtcaatcg caacttttaa tttttcaagt gttccagcag gtgataagac
    53941 ctcgggacgt tttttcatat gtgacatgtg atattctttc tattttcaag ataggtagat
    54001 tacctgtgta atggtgtcat aaccctgtct tgccctgaaa tagtaaactc actcaagaca
    54061 aggattactt atttaacggt ttttggatcg aactcataaa agccagtatc taatccacgg
    54121 ccagctggat gatgggcatg cactgcttga tcaagctttt cagcttcttc ttgggtaaat
    54181 tgcccagctt ctaataaggt tttagcctga ataaacaatt tagtaatagc gacaaaatca
    54241 tcacctggac agtaaatgcc atctagcttc caatgagtta agccatgcgc atacagctca
    54301 cccaatttag acatcatgtc gatatcgtta ttaatgaaaa tatgagtgcc atgattgtct
    54361 tcataaatgg agtaatggct gctagcatct cctggttctg ccaagaaaag tcctcgttca
    54421 cgactaacct catcatcaat ctttgtaaaa tggtaataat tttctagcaa gggacgtttc
    54481 gagtgatgaa tcaccgaggc gccgtaaact agcacctctg ctggaaattc caaattttca
    54541 gctaaggtga ataactctgc tgatgggatt tcccttgcta aaacactttc aacagcacca
    54601 tgttgccccc agaaatttac ctgacggcta gaagtcacaa aaacagaggt atcataaatc
    54661 agtttaaagt tatagccatc ccttttattg acataaaaca cacctgcatc accaaccaca
    54721 agataatcaa cagcaatctc tatcattaag tctaaaaagg gtttgatctg atccatcata
    54781 tcttgatgca tcaaagcatt gcaagctact gtcaactctt tgcctgcatc atgcactagt
    54841 ttggcaattt gtctcaattc atcataagaa aaattatggg gaagacgtaa cccgtaattg
    54901 gcttcaccaa cataaatacg atcaacacca gcagctaata aagctttgac ttgctcaatg
    54961 ctttcagctg tggctgtaat aattattttt tccatataag ctttattata ccaaaaattt
    55021 taagacctta agcatatttc ttgcaaaagc ccaaacgtta agctagtccc cttactgtta
    55081 tagcatgata agtcacttgt cattagtaaa tcttttcaaa tcttttaaaa aaagatgaca
    55141 agaagagact tttatgatag aattacttag tatgttaagg aaaggagagg actatgcctg
    55201 caccgttaaa gaagcataat tcggttgaac aggatgattc ttaccaagaa tctcaaagta
    55261 aatttcgaga ttttcaagag ttcaatggcc aaagtgcaaa gctaaaagaa ttagtcttct
    55321 ttgctcgtat cgctagtttc agccttatta ccgttttatt tgcatttgtc ctgctcgtaa
    55381 tgaatttagc gccaatgttt gctttcttat ttgcaagcat catcagctta ggcattactt
    55441 ccttattagc caaggttatc aaatcattac tgatgtaact tccagagtcc attttgtatg
    55501 actctttttc ttttgccaaa aacaaaaaaa gattgaagcc acaatccccc ccttcttcag
    55561 ttagcctaaa actaaccatc gggactagtg atcagatcct tcaatctttt cttcttctat
    55621 gttttaggtc gttttagtta gtgtttgtct aatgtatcac taacaggctc atcttgttca
    55681 gtatagtcaa tgatgatgtc gtcttcattt aaatcaatga taacatcatc ttgcttttct
    55741 ttcgcttcaa cttcggcaag ggtttctttt gttttttgca cgaaagctgt tgttttatct
    55801 ttgagcaagt ctaacatgtc ctctttagtt aagtcaccag aagccaactt atctttcaca
    55861 tcataaaaag tgtcacgtgc taaatggctg tattcactac ctttttcttt agcaaattgg
    55921 tggtaatcat ctggactttc tttgtaggct tgataagctt tttcagcacg atttttcaaa
    55981 gccttgcctt tttctgttga taagaagtaa gctgccgcta ctcctgaaac agctccaatc
    56041 actaagtttt tgaaactttt attcatgctt ttctcctttt tttccaaata cttttgaggc
    56101 tactttacca actaatgcta attttccagc ttttgaaaca ttacctgtag cattagttgc
    56161 tttttgccca aaatgccttg cttgactatt taaatctgaa agactttctg acaaatcagc
    56221 aatagcaaca aacagtggat cgatggttgc tactttacca ttaacatctt caacaaggat
    56281 attagctttt gctaaaatat cattagtttg atgaagtgtc acattaacat cacttgtcaa
    56341 tacagaaatc gtttttttgg cttcatcaat tgtttctgag actttcttta atacaataat
    56401 caagaaaatc accaaagcaa caaatgcgag tgcaataatc atcagtgaga ttccaactaa
    56461 gtccataagt ttctcctttt tctatcctta ttcttgataa taagaaattc ctttttgacg
    56521 gcgtcttttt atgacaaaga ttaagccaat aataattaat aaggcagaca catattggga
    56581 gatgcgaata cctaaaaaca taagactatc tgttcgcata ccttcaatga ctagtcttcc
    56641 actaccatac caaattaagt aaaatgcaaa gatttctcca tctaatagac tttttggctt
    56701 acgacgccac atcataataa tgacaaatcc caaaagattc caaagtgatt catagagaaa
    56761 ggtcggaatg cggtaacttc cctctataaa catttgcttt tgaataaagc ttggtaagta
    56821 atttaactgg ctcacagctt taccataggc ttcttggttg ataaaatttc cccagcgacc
    56881 gatagcttga gcgaccatga cacttggtgc ggcaatatct aaaaaatgaa tgggattgag
    56941 caccttgtta taacagtaag ccaaaagtac aagagctcct gtaatgagac cgccataaat
    57001 agcaataccg ccattccaaa tggctatgat ttcatctaaa tgcttgacat aataagacca
    57061 ttcaaaaata acatagtaaa ttcttgcacc aacaatagca agtggaaaag caatcagaat
    57121 aaaatcgaaa atagcgtcag atgatattcc ttttttgggt gcttcttttg atgctaagta
    57181 aaccgccaaa acaagtcctg acaagataca tagcgcatac cagtggatgg ctagtggacc
    57241 acattttaag gcaatgggat tgatcattga ctcacctcat ttttggtgat tagttgagtt
    57301 aaacgatctt caaaagtttt tgtagcatca aagcccattt ctttagcccg atgattcatc
    57361 gcagcggctt caataaccac tgaaacattt cgacctgttt ttaccggaat acgaatacga
    57421 gggattctca ctcctgagaa agttatctcc tcattaccgt ttccgagacg atcaaaaact
    57481 ttaccagcct caaagttttc aaggtaaatg gccaattgaa cttgtgatga gtccttcaca
    57541 gcactagctc cataaagcga catcacatca ataataccta ccccacgaat ttcaagcaag
    57601 tggcgcaaga tctctgctgg ctctccccaa agggtttctt catctttggc atagacatcc
    57661 acacggtcat ctgcaaccaa acgatgccct cgcttaacta attctaaacc agtctcactt
    57721 ttaccaattc cagaatcccc ttggataaga acccccatac cataaatatc cattaaaacg
    57781 ccgtgaacac tagtacgttc agctaaagaa gcgtcaagaa aataagacat ttctccagct
    57841 aagcggctag ttgaaacacg gctacttaaa agtgaaatac cttcttcttt tgcagcttga
    57901 accatttctt ttggaatggc taaatttcta gagacaacca ctgcaggagt gtcctttttg
    57961 aacatctctt ttaaaacaga ataacggttg tgagaagtca tctgtgtaag ataagaccac
    58021 tctttcattc caaacagctg caacctttct ggagcataat aatcaaaata accagtcatt
    58081 tcaagacctg gacgtgaaat atctgatgtt gttatctctt ttgacagcaa gttatctgta
    58141 gcataaacca catcaagttt aactttttgc actagcatct ttacagtaac ggtcataatt
    58201 tctccttttt caatattata acacaaatcg accgttagac ccttgcaaat actcattttt
    58261 tcactactaa atgagaacaa cgacaccaaa aatggtctta gctctattaa aaactaggtt
    58321 ttatcattta gagatatgag tcaaaaataa gacaatggca aacaaatact ttactagtat
    58381 cattgagcaa ttagtgctta ttatggtatt taaaaaggta tcatcttact aagtcaaaaa
    58441 gcaaaaagcc tcatcatagc tgataagacc cctcgcttac ttacatatca aaacatttta
    58501 ttatcatcag ttaatcacat ggttgctctt acgtgatgaa ttatcatttt aactgattgt
    58561 ttaccagaac cagccatctt cttcttcatt taagacatca gcgtctttac gacgacgagg
    58621 acctcggcca taacgttctt caagcaagtc ttccttgtaa ggtaagaaga tggccaacaa
    58681 aatataaagc aaaactccaa aaccagttcc gtaaataaga agagccgcta agacacgcgc
    58741 tagagcaaga tcccaaccat acttatctgc taaaccagca atgacacctg caaccaagcg
    58801 attttttcgc tgtttataga atttagtttc cacgtttctt tacctcctca ttctatgata
    58861 ctagtttaca ttgtttttcg caaaataaaa ccagtcttac gactgatttt tttccataag
    58921 tttcccgtgg caatttccac aaacatattt agccagatta atacgccttt ttcgttgata
    58981 aacctgccca caggtttggc aactataatg atgattagtc tttgatttag agctagttgg
    59041 gacataacga agcccgttta cttgagctag cagatctttg aaatccctat ctttatgatg
    59101 gtaccctctt ccttcaaaat aaagatggta atggcagagc tcatggcgaa caattttccg
    59161 aaaaataagc tcaccgtgct cctcaagcat cctagggtta aaatccaaat gaccatcttt
    59221 tggaaaaaag cgaccgccag ttgtttttag gcgcttgttc caataagcct tgtggtgaaa
    59281 tggtttgcca aaatcagcca gggaaacttc ttggacataa ttagtgagtg tcacgcggtg
    59341 gcaataggct gagattgacc ttgtggcggt ccaagtcaat cttagagacc caaacagtta
    59401 ccaagtcacc cactgaaaca acttgactag ggtggttgac aaaggttttg ctcatttcag
    59461 aaatgtgaat aagcccatct tcatgaacac caatgtctac aaaagcacca aagtcaacga
    59521 cgtttctcac agttccttca agcttctggc caatttccaa atctttcaaa tcaaggatat
    59581 cttgacgtaa gattggtgct tcaaagtcat cacgaaggtc acgacccggt ttaaggagat
    59641 cagcaatgat atctttaagg gtttcctgcc caatagccaa tgtttctgcc atttggggaa
    59701 cttgaactgc tgctaaagtt gccttggcag cgtcgtccaa gtcctgaata ccaagtacct
    59761 taaagagttc tttgactgct gggtaggact cggggtgaac tcctgtgttg tctaaaatat
    59821 ttttggctcc tggaattctg agaaaacctg ctgcttgctc aaacgccttg gctcctaaac
    59881 gcggcacttt tttgatgtca gcgcgtgatg tcagtgctcc attttcttcg cggtatttga
    59941 caatattttc tgaaatcgtt ttgttcaaac ctgacacatg tgctaataaa gatggactag
    60001 ccgtgttcac attaacaccg acttggttaa ccacagtatc cacaacaaaa ccaagattct
    60061 cactcaactt tttctgactc acatcgtgct ggtactgacc gacgccaata gatttaggat
    60121 caattttaac caattctgcg agtgggtctt gcaagcgacg agcaatagaa atagcagagc
    60181 gcttttccac tgtgaggtct ggaaactcat ggcgggctaa ctctgacgct gaataaaccg
    60241 aagcaccgct ttcgttaacg atgacatagg acgtatttgg gaaatctttc aaaacgtctg
    60301 ctacaaaggc ttcactttcc cgactggctg ttccgtttcc aatggcaata atatcaatct
    60361 ggtaagtctc aatgagctga gtcagtgttt ctttagctgc ttgaatcttc gtttggctag
    60421 ctggtgctac gggataaata acctgagtag tcaacaattt tccagtctga tcaacgatag
    60481 ccaattttgc acctgttcga aaggcagggt caaacccaag aaccattttc ccttttaaag
    60541 gagacactaa caaaagatga cggagatttt cagaaaagag gtggatagct ccatcttctg
    60601 cggcatcact gagttctgaa cgaacccgtc tttccatagc tggaacaatt ttctttttga
    60661 tggtctgatt gatgacctct tcaatataag ggttggtttc tttgaaccgc acactgaaaa
    60721 agcgttgcat tttctccaag ttatgctcaa aagacacttt taagatgcct aacttttcgc
    60781 cacggttaag ggctaaagta cgatatcctt gcatgttaga cacttggtca gaaaaatcgt
    60841 aatagatttg gaaaaccttt ttctcatcca actgctcatc tttaagcgtt gatactaagc
    60901 ggctgtactg ccaaatctca ttgtaggtcc aagagcgtaa tttagcatct tctgacatgg
    60961 cctccacaag gatgtccaca gctcctgcta gagcttcttg tgggctggca aatccttctg
    61021 tgacaaaggg ttctgctgct gtttcaaggt tttgcgcatt ttgtaaaatc aaacgtgcta
    61081 atgggaacaa gcctgcttca cgcgcaatcg tcgcttttgt acggcgtttt tccttataag
    61141 gcaggtacaa ctcttccaaa tcagcgagtt tctcggttgc ttcaatactc gttcgtaact
    61201 gatctgtcag ttttccctgt tcctcaattt tagcgagaat ggttgctttg cgctcattca
    61261 gggtagtgag agacttatcc atatcaataa tggacttaat caccacttca tctagatttc
    61321 ctgttacttc tttacggtaa cgtgcaataa agggaatggt attgccttgt gctgttaggg
    61381 caagcacctg ttcaatttga tggagactaa ctgacaaagc ctctgcaatg ttgtgattat
    61441 tgttattttc cataatattg ctattataac acaaaccgtg ttaatgcaaa aaatgatagc
    61501 gaaacattgt cctaatataa agttgcgtaa agaatcaaaa aaagctactt ttagtaaata
    61561 actgacgaaa ccctaaataa caatacctaa ttttaaaaaa gaaagaagta aacaacactt
    61621 ccgttttggc attgttctca aatgatagta taatagactt atcttgaatg aaagaaggtc
    61681 atagatatgg caattaccca taaaaaaaat gatgaacttg aaaaaatgct agcaggcttt
    61741 gcatcaatcc ctagttttga taagcctttg gaagtcaata ctgatggtaa actagcgacc
    61801 aaagaaaaaa cgacagaaca aacaaaacca agcaaaccat agctagtttg tctcattctc
    61861 ttaacatatc gtccattcgt ttaaactgag ttgagagatt tttagcgatc aggctaacaa
    61921 aacgtatcag tcgaggctga acattcgtgt ttcagcctcc tcttttatca tctagaaagg
    61981 atatggtgaa tgtcactctt ttccaacctt cctcccagtg tcttgcaatg gtttgcgatt
    62041 tttatgtcca ttatcattga agctcttcct tttgtgctcc taggaactat tttatctggt
    62101 tgtattgaag tctttgtaac gccagaattg gttcaaaaat acctacctaa gcaaaaatgc
    62161 ttgcgcattc tgtttggaac ctttgttgga tttgtttttc cttcttgtga atgcgggatt
    62221 attcccatca tcaaccgctt tttggaaaaa aaggtgccta gttatacggc cgtccctttt
    62281 ctggcaacag cgcctattat taatcctatt gttttgttcg ctacttattc tgcttttggg
    62341 aattctttgc gctttctgat acttcgcttg gtcggtgctg cactagtagc cattacactt
    62401 ggggtaatgt tagcttttat tgtagatgat aacattctca aggataatgc tcaacccgtg
    62461 cattttcatg attattctca tgaaagcttg ccaaaacgca tttatctagc actggtacat
    62521 gctattgatg aattcttcga caccggtagg tatctcgtat ttggaacctt gattgcctct
    62581 gccatgcaaa tatatgtccc aactcgtgtg ttgacaacga ttgggcacaa tcccttgaca
    62641 gccattttga tcatgatgct gatggctttc attctatcat tatgtagtga agccgatgcc
    62701 tttatcggag cttccttatt atccaccttt ggagtggctc cagttcttgc ctttctttta
    62761 attggtccta tggtggatat taaaaacctt atgatgatgg taaaggcttt taaaggacgc
    62821 ttcattgtcc aatttatcgg cgtatccgtt cttatgattg ccgtttattg tttacttgtg
    62881 ggggtgctct aatgattcgc tttttaattt tagctggcta ttttgaacta accatgtatc
    62941 tccagctgtc tggcaaactg gatcagtaca tcaatgttcg gtattcttac cttgcttata
    63001 tttccatgat tttatctttc attttagctc ttgttcaact ctatacctgg atgaaaaaca
    63061 ttaaggtaca tagccattta accggaaaaa tcgcaaggct gaccagtcct tttatcttgg
    63121 tctttcctgt tttgattggt ctccttgtgc caacagtaac cctagattcc accacggttt
    63181 ctgctaaagg ctatactttc ccattggctg cgggagcctc taaaacggga gtcagtgatg
    63241 acggtaccac cattcaatac ctcaaacctg acaccagcct ttactttaca aagtctgcct
    63301 accaaaagga gatgcgtcaa gaactccata aatataaagg caagaaaccg gtcactatta
    63361 ccactgaaaa ttatatggaa gtgatggaat tgatctatct ctacccagat gagtttgttg
    63421 atcgtgacat ccaatacact ggctttgttt ataacgaacc gggccatgat aactaccaat
    63481 tccttttccg cttcggcatt attcactgta ttgccgactc aggagtgtac ggacttttga
    63541 ccacaggtaa tcaaaccagc taccctaaca acacatggct aacagttaaa ggtcgccttc
    63601 atatggaata tgataaaaac ttagaacaac atctacctgt ccttcaactt gctgaggttc
    63661 atcaaaccaa agagcctaat aatccttatg tttaccgcgt tttttaaaga ctaataaaaa
    63721 agcacttgtt ttttatcaaa acaaatgctt tttgcgtttt atcagttagc ataggaacag
    63781 agtcaccatc ttaaacaaga cctatttagg aaaaattatc ctcaaggtaa cgtccattgg
    63841 tttgaatgac ttgtcggtac caatcaaacg attttttctt atagcgtgtg agttgaccag
    63901 taccatcatc atttcggtca acataaataa aaccgtagcg cttacttaat tgggctgttg
    63961 acatagagac acaatcaata cagccccaag cagtgtaacc catgacctca acgccatctt
    64021 caatcgcttt ggcaacttgt acgagatgct gactcatgta gtcaatgcga taatcatcgt
    64081 gaaccgtcat gctgccatct gcggtttgca ccagctgatc ctttgcacct aagccatttt
    64141 caacaataaa caaaggaatc tggtagcggt catagtactg attcaagacc aatcgcagac
    64201 caattgggtc tatctgccaa ccccactccg aagattctaa atatggattg gacaaaccac
    64261 ctagaatatt tccctgacca gatgtgtaag cttcaggatt gtgagcttgt gtgacactca
    64321 tgtaatagct aaaggataga aaatcaaccg tatgttccgc taataattcc ttgtctccgt
    64381 cttcaaaaac aatctcaatc ccattttctt taaaatacga cttaatatat gaaggatact
    64441 tgcctctcac atgaatatct gaaaataaga gattaagatt ttcaaatgca tgcgcagcaa
    64501 gtatatcacg aggatcagag gtcattgggt aagcaggcat cgccaaaatc atacacccaa
    64561 ctttaacatc aggattgatt tcatgcgcta gctttgtgac actagcagat gctaccaatt
    64621 catgatgaat agcttggtat aaatcttgca ggctcagctt ttctttttct gtcatgatgc
    64681 caccactggt aaaaggcatg tgtaaaatcg agttgacttc gttgaaggtc aaccagtatt
    64741 tgactttgcc cttatagcgt tccatgactg tctgagcaaa gcgctcaaaa aagccaatca
    64801 gacgtctatc tgtccaacca ttataggctt tggccaaatg cagaggtgtc tcataatgcg
    64861 acaaggtcac taagggttcg atgccatagt tcaacaattc atcgaataag tcatcataaa
    64921 attgcaaacc tgcttcattg ggctggtcat cgtcaccatt tggaaaaata cgagaccaag
    64981 caatagacgt tcgaaagact ttaaagccca tctcggcaaa aagagcaatg tcttctttgt
    65041 agcggtggta aaaatcaatc gcctctaaag ttaaattatc gctggtagga ctatctgtcc
    65101 attctcctag tccaccattt ggtagaacat cttgtacgga caaacctttt gcgtctgcct
    65161 caaatgctcc ttccacttgg ttggcagcta ctgcgccgcc ccataagaaa tcttttggaa
    65221 aaattcccat tctccctctc cttttaggtt ataaaatgac taacaaagcg tcctctttag
    65281 tcaccatttt tttgtcatct tgaataataa tctccaactg ctcagccgaa ttggtcacga
    65341 ccacaggact gatgagtgaa tagccttttg aagtaatgaa atcaatatcc atttttagaa
    65401 gtgcctggcc tcgtttcacg acatcgccaa cagacactaa ctgctcgaaa ccttgccctt
    65461 ttaactcaac cgtatcaata ccgacatgaa tcaagacttc cacaccacgt gtgtttttta
    65521 aggcaacagc atgcttggtt ggaaagaaag tgatgacttc accatcaaag ggggcataga
    65581 ccacaccttc gcttggtaat atggcaaatc cttctcctaa taacttggaa gaaaaggttt
    65641 catcaggaac ttctgataga aaaagcatct cacctgtcat tggagcatac aacgtttgtt
    65701 tggttgacaa gccgctctta acttgtgaca tatctgctgc aacactcact tgctttgggg
    65761 actcttcatc aattcccatg aaccaagtca aactgaaggc taacacaatc gtcgcagctc
    65821 cggcaatcaa agcatttgta aaattagctc cgcctgatgg gttgatgtac tgtggtaaac
    65881 caataataga aggtacgaca aaggtataag aagcaatatt gacaaaacca ataaaggctc
    65941 caaccagacc acctgaaatc atggctgcat agagtggctt tttaaatttc agtgtgaccc
    66001 cataaagtgc cggttccgtg atacctgcca gcaaagctga aatccccgcg gcaagggcaa
    66061 cttgacgtgt ttgtttctgc tttgttttaa aggcaacagc caaagatgcg gctccttgag
    66121 ccaaattaga agccaacatt gctggtaaaa tcaagacatc tggtgttgcg accgaagcgg
    66181 ccaaaaagat tggtgcaaaa gcccagtgca tccccgtcat gacaacaagc ggcataatcg
    66241 ctcccaaaat ggcaagtgct agccacggag ccacatgata aatagcgagc atggtattag
    66301 ataacccttg accaataatc acaccaagag gacctacaac cactaaagcc aaaaagccag
    66361 aaatcaaaat gattaaggtt ggctgtaaga agcttttcat cacgcttggc accaagcgat
    66421 tgacccattt ttcaatgtat tgcatcaagt aaaccatcat caaaatggga ataacagatg
    66481 agccatagct agcaggagtg actggtgctc caaataaagc caatggttta ccttctgcta
    66541 ccattgcaac aaaggcagga tgcaataaaa tccctgcgat cgtcgctgct aaaacaggtg
    66601 tcaccttaaa gcgcgccgct gctgaatagg caatcatgac aggcataaaa taataagccg
    66661 catcgccaaa gaagttaata aaggcaacgg tttgagagtc cgcactcgct aagccaagca
    66721 taggaagcaa gatccccacc actttgagca ttccaccacc aagaagggct ggaatcagcg
    66781 gtgtaatcac accagcaatg gtttcaatca agcgctcaag gatacttcct ttcgcttttg
    66841 aagaatgatc ttcatcttga ttgtcaaaat gccctaggct taaaaaggct tggtaataat
    66901 tattgacatc attgcccaag ataatttggt actggccgtt tttgcgcatc acgccaatca
    66961 catttgaaat ggctttgact tgctgatctt taactttctc atcatttttc agtactaagc
    67021 gtagacgtgt tacacagtgt gtcacacgtt gaatatttgt tttgccacca accgccgcta
    67081 aaatagcctt ggcagtttct tgatacgtca tattaagtct cctttaaatg tttcactaaa
    67141 cgtttaacat gaaccgtcaa atacaaaagt tcgcttgaat taaggtgata gttgtaccgc
    67201 ttttttatct cctcactaat atctaagacg caccgatatt ctttagggta tttcgttttc
    67261 accactataa gcagttctgc atcatcatca tcgtaagaca tctctgataa cacacgttga
    67321 gcaaataatt taatatgggt cataaagcgg taataatcga tggatgtgtc atccaattct
    67381 gttttgaagt ctgttttgat tttttgctca atataagaaa caatctccgt caggcgatgt
    67441 ggctccttaa aaggagtgtc caaactagca ttgacaaaat gcatggcaat aaaagctgct
    67501 tcatcaatag ctagagtgac tcctagatta cgctcaatta gctctaaggc ttttacccct
    67561 agactatatt catcaggata atagcgttga atctcccacc gtagtgggtt atgaatcaac
    67621 attccttgct catgcctttc aatagcagag tgaatatgat ccgttaaatt aatatagaga
    67681 atttcatcta aggttttgcc taatttaatt ttacctagat tgataattct ctctgagcaa
    67741 gcaacaactt cttgtggcac cgtaataaat aactctgtga agcgattcat attgtcacta
    67801 ttttttaaaa caaatgatgt ttcgatagca ttaagctcaa tactatctcc aacttttttt
    67861 ccaaaggcaa tcccttttcc catcaataaa atatctaatc cttgatggtt ggtcgaaatc
    67921 gccgcattat ggtttaaaac gcgtttaatc aacataaaag tcctagtcct ttagtatcac
    67981 aataaaaaat gacctatcca aaagctcgct aaaaagcact tttcgaatag gtccctgctc
    68041 acaaaactgt gataacatcc tttaatattc tgattgttat gtctctagcc tgcttacttg
    68101 aagtaatcac atctgagaac gctttaatgt tatcatctct ttaagattct gtcaagcgtt
    68161 ttcaaaaaat tctctgaaag agcaactatt gttattcgta tctattgatt tagcaaaaaa
    68221 gagtttctga caattttaag attatatgat acaataacaa tcgattagat aaaggagtta
    68281 tcatgtcaca tcatcaacaa accgtttcaa aacaaacaat tatggcgatt atcgccatag
    68341 cactcattgg tttttcagga attttgtctg aaaccagtat gaatgtcacc ttcccgacac
    68401 tgatgtcagt ctatcagttg cccttaaata gcttgcaatg gatgacgacc atttatttac
    68461 tagcagtggc gattatgatg accacttcgg ctacactgaa aaaaaatgtg cgggaaagac
    68521 ccctcttttt tatggccaca ggtcttttta catttggcac catcttggcc gttctgaccc
    68581 agtcctttgc gatcatgttg ctagcccgca tttttcaagg cattggtact ggtctggtaa
    68641 tgcctcagat gtttaatatt attttagagc gtgtcccaat gcataaggta ggtctattta
    68701 tgggatttgc tggtcttatt attagcttag cgcctgcttt tgggcctact tatgggggct
    68761 ttatgattag ccattttagt tggcaatgga tttttatctg tatactccct gtaccactga
    68821 ttgcaggtat tctagcttat tattacctcg aagattctcc agtaagcgaa aaagtaccct
    68881 ttgactggtt ggcatttatt gcactatcga ttagcttaac ttctgcctta ttagctatta
    68941 ctagtctaga aaacggaagt gttaatttgt attacttagg gctttttatt ctcagctttg
    69001 tcctcttcct ctacaagaat ctcacagcta agcaaccctt tcttgatatt cgcattctta
    69061 aaattccctc tctaaccttt ggcctgattc ccttttttgt cttccagctg attaatttag
    69121 gcataaattt tctaacgcca aactttattg tcatggaaaa gattgcgaat agttctcaag
    69181 ctggtatggt attactacct ggtaccttac tcggagctct actagcacct gcttttggta
    69241 aactttatga tcaaaaagga gcaagacttt cgctttattt aggaaatgcc ttatttagtt
    69301 tatcattgat tattatgaca cttcaaacaa gacattttat gcttttacca ttcactcttt
    69361 tatatatttt attcacgttt gggcgtaaca tgggctttaa taatagctta gccacggcta
    69421 ttcgagaatt gcctgccgag aaaaatgccg atgccacggc catttttcag atgatgcagc
    69481 aatttgctgg cgctctagga actgctatgg catcactgat agcaaatagt caaccagaat
    69541 tcacaagcgg tgtccagtct gtctaccttc tctttactat ttttgctcta cttgatttta
    69601 tctttttctt tgctatgttt taccatttag ggaaaaaagg acttgcctaa gctgacttac
    69661 ttaaaaacca gcctcgttct gttgaacaag actggttttt ttcttataaa ataccttcta
    69721 aaagaccttt cataaagtct tctgagtgga attctccaat atcatccact ttttcaccaa
    69781 atccgatgaa cttgactgga atgtctaatt cttgacggat ggctaggacc accccacctt
    69841 ttgcagtccc atcaattttc gttaaaatta agcctgttaa aggtgttatt tttgaaaatt
    69901 ccttggcttg gctaagcgca ttttgacctg ttgacgcatc taaggccaaa agcgtttcat
    69961 gaggggcatc tggtagaacg cgcttaatga tacgacccat tttttccagc tctgccatga
    70021 gattttcttt gttctgcagg cgaccagccg tatcaatcag aagaatatct acttcttttg
    70081 ccacagcttt ttccatcccg tcaaaaacaa cagacgctgg atcagccttt tcagggccag
    70141 taatgactgg cacatctact cggcgtcccc attcgactag ctgagccaca gcccctgctc
    70201 ggaaggtatc tgctgccacc aacatgactt ttttaccttc ttgtttgtaa cggtaagcca
    70261 gcttcccgat tgaagtcgtt ttaccaaccc cgttaacacc tacaaaaagc ataaccgtca
    70321 agccatcttg ataattaatg gcttcattat aacgcccgtc tttttcatag atatctacca
    70381 atttttccac aatcacacgt ttcaaggcat ctggtttttt cgcattttcc agtttggctt
    70441 cataacgcaa ctcctctgtc aaagttgtcg ccacatgtac accgacatct gataagatca
    70501 gcatttcttc caagtcttca aagaattctt catccactcg cctgaaattg gcaaagaaac
    70561 tgttcagacg agctgagaag ccagtccgcg tttttttcaa gctacgcttg tatttttctt
    70621 gatctgtctc aggaatggta tcgtaggttg ccttgttttg agaagcttct gctgaggtag
    70681 aggcttgatt ttcttgtgga acttcttctg gcatcactgg aaccgttgcc gctgcttttt
    70741 cttgaaggct tttttcaaga gcagccttac gacggtagta gtcttccata acctgttggc
    70801 tactggattg ctcttttgaa gtgtctactg cttcttcatt cgccgaatca tttgaggcat
    70861 cagcttgggc ttgttttgtt ggaaactgtt ccacaactgg ctggtcaaca aggtcttttg
    70921 gttctgatgc cgtagattga ctaagttcac ttaccttaag atctgttttg tcggcagcaa
    70981 actcattggt atcttctgat gaatgattac tattatcacc tgtttcttcc tcaacctgtg
    71041 catttactga agctgcttcg ggaccatttt ccaccgaacc tgcgccctct gaagaaacgt
    71101 cctcttgttg aaccacctca atcttgtctt gctcattggc tttttcagaa agctcctctt
    71161 tctgagttgt ttctgtcaaa agattttctt ctaacttttc ctcagctacc ttcggggttt
    71221 cttttttccc aaataaacga tcaaataatc ccattaactc tcctcttcta aaataaatgt
    71281 cttcacagct tctgcaaccc cagactcatc attgatcaag gtggtcacgg catcggcaac
    71341 ggctttagct cctgaaacac cattagccat agctactcca agtcctgccc attctaacat
    71401 cgcaaagtcg ttagcttcgt ctcccatagc catgacatgt ctagcgtcaa ggccaaggtg
    71461 ctgacaaagc aagtttaatc caaaagcttt atcaatgcct tttggcatga tttcaaaaat
    71521 aatatctcgt gatttaaagg cttcaaaatc ctcaaataag cttggggata gctttataat
    71581 ctgctgatcc aaaaagtctg gatcggtgac tgtcacaatt ttgttatagg taatgtcttt
    71641 tggtagttcc gctacagatg tcacctcaat aaaggtcaac agtgggttag ctagatggta
    71701 ctgcgaatgc ctaccgtcct tacttggaat gctatacaca tccccaccac tgataatatc
    71761 tgttggtaag ccaaccgcct ctaaagcttg ctgaatctgg caaacctggt caaaactgag
    71821 agagctctta tccaaaacct cccctgtatt tcgctgaacc aaacccccat taaaggtaat
    71881 actgtagtca tcgtggtcaa gcaagtccaa ctcttctagc aagttaccga tggcctttag
    71941 agggcgacct gtggtaataa ccaccttaac ccctttttct ctagccgctg ctaaggcttt
    72001 tttattggca tctgtgacaa ttttttcagt gttgtagagg gtaccgtcta aatcaagcgc
    72061 caaaattcta atattcatga gttacactag tccttttaaa tacgttagta ctgctccgtc
    72121 attacagtgg ccaatgactt ggtctgaaat cactttgatt tcaggtcttg cattttccgt
    72181 agcaatagcc ctaccagcaa actccaacat ctggtaatca ttaaaattat ccccaaaagc
    72241 aatcgtttct gctttcttaa tgcccaaggc ttgacaaaga tgctccatac caaagccctt
    72301 attcacctct tttaagataa tatcaatgga atcaaagccg gtggtcactg cagtggcata
    72361 agggagggct tgattcaacc aatcgcttcc ttctaagacg gtatggcctg tgaagttggt
    72421 agaaacttta aaaatggcgt cattctccat atcttcaaaa ccattaataa ccttaacatt
    72481 agcatagtaa tgttttgttt tttgaatgta ctcttctgat gcgcctttta aaatataggc
    72541 tgccttttgc ccagaaaaaa ccatacctgt ttctacatag tgaggattgg ctaaaacctt
    72601 ttttgcaact tcggtatact gctctttggt catcatatct gcaaatagaa tctcaccacg
    72661 gtattgaacc acggaaccat tttctgcaat aacagcaatc tgatccaaaa agggctcaaa
    72721 gagctgatca atggctaaga gcgagcggcc actcgaaacc gcaaataaaa tgcctttttc
    72781 ggctaacttt ggcaagagcg cagctagttg ctcttgatta taagtaccat cttcagctag
    72841 gaaggtacca tccatatctg ttgctattag tttaatcata caatctaacc tttacccttt
    72901 ttagggagtg caaaattcaa atgaatcgtg catctcaact cccaatataa cttctttcat
    72961 tataccacag ataaactaaa aaaggacgtg ccgaattgat acgcccttgc cttttatcaa
    73021 tcaatccgta cgccattttt gaaggttagg ctgatgtgct tgtctacttt tatatccaac
    73081 ctttcaacac ttgtctgcca gagttctccc tttggaccag gagttaaaga gatggttgta
    73141 aggtcagctt gtgtcgctag actttcccct ctcaccttta ggagcggtgt gtcaatggaa
    73201 agattcccat tcccatccct atcccaacta aagactggag tattctgtcc tggaataacg
    73261 accttatcag cttcaacttc taggctcttc acatactctg atagaatctg ttgggagata
    73321 agccttgtca tccatgctga actagagacg gtcaactcat caatcttagc tttttgaagt
    73381 gctgcaactc gtgcttctaa gacatccgtt gccagataat caagagcagc tttcttatca
    73441 aaacgctcgc cttctgcttt agcagtagcg ataccatacc acttttatct cgtataatct
    73501 gtacataggc atttccccat atcaaaagat ggctcatgat tgtctctcga aagataaagg
    73561 aggacatctc tggattgggt tcatcatgaa gaagaaagta cagtgggtgg tccagctttt
    73621 tctccttccc attttctgtc cgttcataga tgtgaatagg aagtgacgcc accgcttcag
    73681 caagaatacg cacacaggca tagactgccg tcgtctgcat agtcttaaac tcatccacat
    73741 tctcgccact aatcgtgcga ccaaagaggt aggaaaagtc ctgaccttca taactgtttt
    73801 ggggcttatc tctagccctt tttcttccaa ttaaatcaag tagtcccata agccctcctt
    73861 attttggggt acaaaaaaag cacctccttt gaagtgcttt cggtatattt ctttcaaagt
    73921 aatcaacagt ctttcttaca aaacctagta ttctcattct gtcaattcct taaatgcgtc
    73981 aagatgtcgt gataatactg aagtcgcaat ctcatctaac cttgcttgtt caacaactgt
    74041 tgtcatctgc tcatcaccaa agttccatca gttgatttat aaaggttaaa ctcctgattc
    74101 tcttgaatgc caaatgggtc aggtatcgga agatagatgt catcaccaat ttgtatcgtc
    74161 tttacgagtt ccatacatca ctctccctta ctttaccaat tattcatatg acgtgatcca
    74221 tagacgaccg caacaattat aacttcatct tccagaacat gatatacaat gcgatatttt
    74281 ttgacaatca gttgtctgaa ggtatagcct tttccaatca gatcctcaat gatggcacaa
    74341 cgttcaggaa aaatggatag tgataacatt ccttgggata acctctcaag aagattatcc
    74401 gctgcctgtg gtgcacagag ttcatcacga acatagtgat agatgctcag caaatctgct
    74461 ttagcatcat ccgacatggt gacctgatat tctttcatta agcattttcc ttcaattgag
    74521 atagaaattc tctgacatcc tgacggttgc cagttttcgc atcttcaaag ctggtgataa
    74581 gcttatcata aaacttctcc tgactcatgt aatcaacatt aactcgttga ggcgcttcag
    74641 gtagagaaac atcaaatggg atacccccag tcaaaataat ctgattcaaa aacatatcaa
    74701 tcgcagttga cataggaata cctaagcgtt tcaaaatatc atctgcggca ctttttactg
    74761 aatcatcaac tcgtaaattc aaagttcccg ttttagccat ggttatcctc cttttttgta
    74821 acgacattgt atcacgtttt tagagttgac tcaactaaaa actcaatatc cctcgctcat
    74881 catagacgct agcttcatca ccttggcggc gaatgcaacg gtcaagcccc aggataagac
    74941 ctacaatacc gtcaatcttc tcaacagatt tttccttatc tggcttgatg ttgcctccag
    75001 gggcttgtcg catcaccacg ttttgtccca tccatttaag gactggatga ccaccatgtt
    75061 agattttccc ttccatcatg agtttataga gttccttgga cggtggactc atatccttat
    75121 aactctgctc aaaaggcacc atggtcaagc cgacaccgca attccaaggt atcttctagt
    75181 aaccatcaga gagaagacag ggattgtaaa atcaaccact gtgcaaaata ctgcgttcac
    75241 tacccagtcg aatcagctca aaaaacaata cgggcagttc ttgttaacag aatctaataa
    75301 ctgttgtgca tgcccaggct gtgatagacc actcattcta accagtggca acttagcagc
    75361 agaaaattac gaggtttcag ccattgaaaa agataaggac gctgaaccac tgaatctgat
    75421 agccctctgc ccagattgtt ttttaaccta tcaagcagat agtcgcaaaa aaattgtaac
    75481 agctctaaaa aatgttaaaa agattctagt ctctgcacat aacagccaac aagcgatttc
    75541 tgatatgaag ttagacagtg gaattgtttc agttttgact agtctcaata aactaaaatg
    75601 tgatgaatat gatatctcct atgactcgaa gcaattgact gataagatat cacctgagaa
    75661 caatcgtacg ctttatcaat tggttaaaaa cccagttatt gataactact taaccattca
    75721 aaaaatcatc gtaaatttgg acaaacaagg aagaattgat tacgaggaaa tccaatatca
    75781 aacgcgatcg atgtataaaa agttaaaggc tgccaagcat aataatctgg ctattttcaa
    75841 tactatttcg gaaaaactcc ataaagctac actacaggac atctacttct gccagatgat
    75901 tgtctcttac tttatccaaa aatgcgaggt acttgaataa tgcaattacc aaataaactt
    75961 tactcctatc aaaaaagcac ccttgcctat ttacctagag tgctaaatga aatcaaaagt
    76021 ggaaactcaa acgtcaaaga tatctttcac gctatctcag aagagttgga tgatcctaca
    76081 gatttcctat ctataatgga ttgcttgtat gcattgaacg ctattgaaat gtctaatgaa
    76141 ggagaagtaa aattatgctt atagaaatgt ggtctccagt atttaagaat cacggagaaa
    76201 ttcgggaatc aatctgcttc cactatgggt taaacgtgat tatggggatg gatttagctg
    76261 ataactctat cggcaaatcc tcctcactat tagccattga tttcatcttt ggaggtaata
    76321 gctatctaaa atcaattgcg gttaaaaaat taggtgatca tcctatctac ttctgctttc
    76381 aatttgagaa aaagttttat ttttcaagag atacggccaa cccaaatatc attctagtgt
    76441 gtgataagag ctactctcca accggtgaaa caatggacct aggaattttt cttaacagac
    76501 ttaagaaacg atatcattta gattctccag agctatcatt ccgattagct atgagtggct
    76561 tctttaggat tgcaggaaaa agtaatcaaa ataccgattt tcccttacaa gtttattcga
    76621 gccaaaaatc ttctgaatct attactactc tcatccaact gtttaatttg tatgataaca
    76681 ttgcacgata caaagaacgt ctgaaagata agagcgacca gttaacaact tttcgtaatg
    76741 ctcgaaagta taccttcatc tccaacctgg ttggcggtaa aaagcaattt gaagcaaatg
    76801 tctcagaaat aaaaagattg gaatatgatt tagcacatct ccaagacact catcaagata
    76861 aaattgactc tgatgatatt gagaaaaatc aacaaaaact ccagcttaga aatactaagc
    76921 tggagttaga aagcagtctt cgggacaagc aaagacgtct taagctattg gacatcagta
    76981 tcgaatttgg cttatatcct actgaatctg acttaacaga gcttcaacaa tacttcccag
    77041 atactaatct caaaaaatta tatgaagttg aagcttacca caaaaaattg gaaactattt
    77101 tagattccga attctcaact gaacgtgaat ccctaatagc tgagatcgac gaattagaga
    77161 gtcaattaac aactctaaac caagaacttc aagaactagg aaacatccca aatctttcaa
    77221 gtgagtactt agaaagctac tctaaactaa cagctacaat caatgcacta aaagaacaaa
    77281 acgaggccta cttaaaggag tctggtctat ccaaagaaaa atcagaagcg gacgctgact
    77341 tgaaacgcag tacagaagat atccttctag atctagaagt aaaaatcaac agtaagatgc
    77401 gtgaattcaa taacattcta tatccagata ttcgcaaagc tcctcaaatt aacctcaatg
    77461 ctcacaatag ctactccttc tatacaccag atgatgatgg tacaggaact aagtttaaag
    77521 ggatgattgt attcgactta gtaatgctct accttactaa tctgccagca ctcacacacg
    77581 attcattact cttgaataat gttagctacc aagcgactga agcacttttg aagctgtatg
    77641 accagtcaag gtcattgaac aaacaagtct ttttagcctt cgataaagcc agctcttatt
    77701 ctccagatgc taatcaactc ttgtcagaaa atacggtatt gagactctct agtaacggaa
    77761 atgaactcta cggtatttca tggaacaaag gagaaaactc agatgagatt tagttacaat
    77821 aaattatgga aacttcttat tgataaaggt tggaccaaaa caaagctcag gcaagaagct
    77881 gggattagtt cttccacgat cgcaaaattg ggaaaagggg aaaatatcac tactgatatt
    77941 ttattggaaa tttgtattgc acttgattgt aagattgaag atatagtaga aattgtagat
    78001 aataatatct agaaataaaa aaagcactaa gttgataaga tgtgtaagtc agatcaactt
    78061 agtgccttta ctttgaaaaa aataat
//
LOCUS       DAUGOH010000005        74242 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUGOH010000005 DAUGOH010000000
VERSION     DAUGOH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74242
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.005"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            79..333
                     /locus_tag="VH957_000321"
     CDS             79..333
                     /locus_tag="VH957_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEQ8558265.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            351..746
                     /locus_tag="VH957_000322"
     CDS             351..746
                     /locus_tag="VH957_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEQ8558266.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            1031..1350
                     /locus_tag="VH957_000323"
                     /pseudo
     CDS             1031..1350
                     /locus_tag="VH957_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264372.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            1347..1910
                     /locus_tag="VH957_000324"
     CDS             1347..1910
                     /locus_tag="VH957_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8558267.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTQLTAAETAQLIIQKMTHIKEN"
     gene            1912..4560
                     /locus_tag="VH957_000325"
     CDS             1912..4560
                     /locus_tag="VH957_000325"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEQ8558268.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKCVHSVGHSERSGAAVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTAVYPTVTPTFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            4714..7122
                     /locus_tag="VH957_000326"
     CDS             4714..7122
                     /locus_tag="VH957_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEQ8558269.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWNYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSIVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLS
                     AEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSA
                     SFYF"
     gene            7255..7983
                     /gene="cas5c"
                     /locus_tag="VH957_000327"
     CDS             7255..7983
                     /gene="cas5c"
                     /locus_tag="VH957_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEQ8558270.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            7983..9878
                     /gene="cas8c"
                     /locus_tag="VH957_000328"
     CDS             7983..9878
                     /gene="cas8c"
                     /locus_tag="VH957_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEQ8558271.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRSNESVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QTQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGI
                     CNISGREEQLTDKHRGLMGNTKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYHKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            9883..10731
                     /gene="cas7c"
                     /locus_tag="VH957_000329"
     CDS             9883..10731
                     /gene="cas7c"
                     /locus_tag="VH957_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEQ8558272.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKPIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTV
                     EILEGL"
     gene            10733..11407
                     /gene="cas4"
                     /locus_tag="VH957_000330"
     CDS             10733..11407
                     /gene="cas4"
                     /locus_tag="VH957_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEQ8558273.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQI
                     LHTKADNPYIKEKRKDLLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            11404..12429
                     /gene="cas1c"
                     /locus_tag="VH957_000331"
     CDS             11404..12429
                     /gene="cas1c"
                     /locus_tag="VH957_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8558274.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            12440..12733
                     /gene="cas2"
                     /locus_tag="VH957_000332"
     CDS             12440..12733
                     /gene="cas2"
                     /locus_tag="VH957_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8558275.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVNYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   12882..13776
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=12882..12913
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaat"
     gene            13936..14646
                     /gene="ccdA2"
                     /locus_tag="VH957_000333"
     CDS             13936..14646
                     /gene="ccdA2"
                     /locus_tag="VH957_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEQ8558276.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNIFYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            14659..15282
                     /locus_tag="VH957_000334"
     CDS             14659..15282
                     /locus_tag="VH957_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEQ8558277.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            15325..16431
                     /gene="msrB"
                     /locus_tag="VH957_000335"
     CDS             15325..16431
                     /gene="msrB"
                     /locus_tag="VH957_000335"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8558278.1"
                     /translation="MEHKWKLWLFIVGVVFLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSAAEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVIRYKEDKSFNMTRTEVRSRSGDSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            16519..17259
                     /locus_tag="VH957_000336"
     CDS             16519..17259
                     /locus_tag="VH957_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8558279.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLIQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLIGVTPSQYKKGDQA"
     gene            17256..18989
                     /locus_tag="VH957_000337"
     CDS             17256..18989
                     /locus_tag="VH957_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8558280.1"
                     /translation="MKRYPLLVQLISYIFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLIMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIKNGYAKDKSSFVYQRVIPNSQWTLIGVASLDQLHRV
                     QRQIFWSFLGMGLLACLICGLTTILVLRKWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYD
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDHFTEIQLTLPKMH
                     ELMADDTQENE"
     gene            19062..20141
                     /locus_tag="VH957_000338"
     CDS             19062..20141
                     /locus_tag="VH957_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEQ8558281.1"
                     /translation="MSLASDYFSRQTPIVEKLVAYGFEKRDNGYFYNERFMEGEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLGRLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYVCQVLETNIPNEGYRKNPNIDKLMRLRKRQQYKDGLLSFDLMKEHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            20155..20871
                     /locus_tag="VH957_000339"
     CDS             20155..20871
                     /locus_tag="VH957_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEQ8558282.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     ITSVHVLDKDNPHVLLFTEN"
     gene            complement(21037..21510)
                     /locus_tag="VH957_000340"
     CDS             complement(21037..21510)
                     /locus_tag="VH957_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8558283.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            21652..22332
                     /locus_tag="VH957_000341"
     CDS             21652..22332
                     /locus_tag="VH957_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8558284.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
     gene            22606..23841
                     /gene="arcA"
                     /locus_tag="VH957_000342"
     CDS             22606..23841
                     /gene="arcA"
                     /locus_tag="VH957_000342"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEQ8558285.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            23941..24369
                     /locus_tag="VH957_000343"
     CDS             23941..24369
                     /locus_tag="VH957_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8558286.1"
                     /translation="MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            24409..25422
                     /gene="argF"
                     /locus_tag="VH957_000344"
     CDS             24409..25422
                     /gene="argF"
                     /locus_tag="VH957_000344"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEQ8558287.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            25592..27085
                     /locus_tag="VH957_000345"
     CDS             25592..27085
                     /locus_tag="VH957_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEQ8558288.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            27102..28433
                     /locus_tag="VH957_000346"
     CDS             27102..28433
                     /locus_tag="VH957_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEQ8558289.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPKGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTEPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAAQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            28453..29403
                     /gene="arcC"
                     /locus_tag="VH957_000347"
     CDS             28453..29403
                     /gene="arcC"
                     /locus_tag="VH957_000347"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEQ8558290.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            29716..30708
                     /locus_tag="VH957_000348"
     CDS             29716..30708
                     /locus_tag="VH957_000348"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEQ8558291.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            30831..31370
                     /gene="rsmD"
                     /locus_tag="VH957_000349"
     CDS             30831..31370
                     /gene="rsmD"
                     /locus_tag="VH957_000349"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEQ8558292.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            31360..31851
                     /gene="coaD"
                     /locus_tag="VH957_000350"
     CDS             31360..31851
                     /gene="coaD"
                     /locus_tag="VH957_000350"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEQ8558293.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            31838..32875
                     /locus_tag="VH957_000351"
     CDS             31838..32875
                     /locus_tag="VH957_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEQ8558294.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            33297..34274
                     /locus_tag="VH957_000352"
     CDS             33297..34274
                     /locus_tag="VH957_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8558295.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTTYVCDSQNFDFESIQ
                     LEASSNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            34698..35342
                     /locus_tag="VH957_000353"
     CDS             34698..35342
                     /locus_tag="VH957_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEQ8558296.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRVSKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            35346..36425
                     /gene="rlmN"
                     /locus_tag="VH957_000354"
     CDS             35346..36425
                     /gene="rlmN"
                     /locus_tag="VH957_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEQ8558297.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILDDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(36507..37133)
                     /locus_tag="VH957_000355"
     CDS             complement(36507..37133)
                     /locus_tag="VH957_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEQ8558298.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQLQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            37361..37888
                     /locus_tag="VH957_000356"
     CDS             37361..37888
                     /locus_tag="VH957_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEQ8558299.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            38030..38233
                     /locus_tag="VH957_000357"
     CDS             38030..38233
                     /locus_tag="VH957_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEQ8558300.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            38238..39209
                     /locus_tag="VH957_000358"
     CDS             38238..39209
                     /locus_tag="VH957_000358"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEQ8558301.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            39219..39608
                     /locus_tag="VH957_000359"
     CDS             39219..39608
                     /locus_tag="VH957_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEQ8558302.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFSAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            39790..41631
                     /gene="typA"
                     /locus_tag="VH957_000360"
     CDS             39790..41631
                     /gene="typA"
                     /locus_tag="VH957_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEQ8558303.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            41753..42004
                     /locus_tag="VH957_000361"
     CDS             41753..42004
                     /locus_tag="VH957_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEQ8558304.1"
                     /translation="MFYLIMAVLIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            42360..43718
                     /locus_tag="VH957_000362"
     CDS             42360..43718
                     /locus_tag="VH957_000362"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEQ8558305.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISAILAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYSNFEVRGDEFLATFDCLRG
                     DA"
     gene            43718..44800
                     /locus_tag="VH957_000363"
     CDS             43718..44800
                     /locus_tag="VH957_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEQ8558306.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFILAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            44801..45949
                     /locus_tag="VH957_000364"
     CDS             44801..45949
                     /locus_tag="VH957_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEQ8558307.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLI
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMYDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQAPPSPETVLEQAHG"
     gene            46160..47524
                     /gene="ftsA"
                     /locus_tag="VH957_000365"
     CDS             46160..47524
                     /gene="ftsA"
                     /locus_tag="VH957_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEQ8558308.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            47548..48867
                     /gene="ftsZ"
                     /locus_tag="VH957_000366"
     CDS             47548..48867
                     /gene="ftsZ"
                     /locus_tag="VH957_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEQ8558309.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            48870..49540
                     /locus_tag="VH957_000367"
                     /pseudo
     CDS             48870..49540
                     /locus_tag="VH957_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
     gene            49552..50208
                     /locus_tag="VH957_000368"
     CDS             49552..50208
                     /locus_tag="VH957_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEQ8558310.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            50213..50467
                     /locus_tag="VH957_000369"
     CDS             50213..50467
                     /locus_tag="VH957_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEQ8558311.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            50467..51258
                     /locus_tag="VH957_000370"
     CDS             50467..51258
                     /locus_tag="VH957_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEQ8558312.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            51268..52026
                     /locus_tag="VH957_000371"
     CDS             51268..52026
                     /locus_tag="VH957_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEQ8558313.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSMTEPEVNLSETQTFKLNI"
     gene            52299..55100
                     /locus_tag="VH957_000372"
     CDS             52299..55100
                     /locus_tag="VH957_000372"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEQ8558314.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQESN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRNDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNTKENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(55365..55667)
                     /locus_tag="VH957_000373"
     CDS             complement(55365..55667)
                     /locus_tag="VH957_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEQ8558315.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(55718..56173)
                     /locus_tag="VH957_000374"
     CDS             complement(55718..56173)
                     /locus_tag="VH957_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8558316.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(56301..58583)
                     /locus_tag="VH957_000375"
     CDS             complement(56301..58583)
                     /locus_tag="VH957_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8558317.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPTNSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            58882..59112
                     /locus_tag="VH957_000376"
     CDS             58882..59112
                     /locus_tag="VH957_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEQ8558318.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            59239..59925
                     /locus_tag="VH957_000377"
     CDS             59239..59925
                     /locus_tag="VH957_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8558319.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISISVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMITTVMAQLLAVL
                     ERHMAQGGNH"
     gene            59925..60659
                     /locus_tag="VH957_000378"
     CDS             59925..60659
                     /locus_tag="VH957_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558320.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            60808..62217
                     /locus_tag="VH957_000379"
     CDS             60808..62217
                     /locus_tag="VH957_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEQ8558321.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQNHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            62395..64089
                     /locus_tag="VH957_000380"
     CDS             62395..64089
                     /locus_tag="VH957_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8558322.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYEEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            64296..65150
                     /locus_tag="VH957_000381"
     CDS             64296..65150
                     /locus_tag="VH957_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEQ8558323.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            65303..66643
                     /locus_tag="VH957_000382"
     CDS             65303..66643
                     /locus_tag="VH957_000382"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEQ8558324.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQLLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            66621..66836
                     /locus_tag="VH957_000383"
     CDS             66621..66836
                     /locus_tag="VH957_000383"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEQ8558325.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            66836..67708
                     /locus_tag="VH957_000384"
     CDS             66836..67708
                     /locus_tag="VH957_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEQ8558326.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            67701..68528
                     /locus_tag="VH957_000385"
     CDS             67701..68528
                     /locus_tag="VH957_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEQ8558327.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKFKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            68515..68985
                     /locus_tag="VH957_000386"
     CDS             68515..68985
                     /locus_tag="VH957_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8558328.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            69007..70668
                     /gene="recN"
                     /locus_tag="VH957_000387"
     CDS             69007..70668
                     /gene="recN"
                     /locus_tag="VH957_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEQ8558329.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIVKEY
                     QLLTGDELSSGDLEAELKALEKQLVAAASELSVSRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTSEERVEEIARMLAGADMTEAALTQARELLAKH"
     gene            70876..71823
                     /locus_tag="VH957_000388"
     CDS             70876..71823
                     /locus_tag="VH957_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8558330.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFNDDSFISQNETDKMFENLTDDR
                     LLNELDELDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPH
                     LRSLSDTALRSGEIRGHLDNKLDTLSVTATKLALTMAQKFDLTTHVYSIGESFSEVLA
                     AHYEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAV
                     AKRKIALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            72039..72890
                     /locus_tag="VH957_000389"
     CDS             72039..72890
                     /locus_tag="VH957_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8558331.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            72883..73725
                     /locus_tag="VH957_000390"
     CDS             72883..73725
                     /locus_tag="VH957_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEQ8558332.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            73703..>74242
                     /locus_tag="VH957_000391"
     CDS             73703..>74242
                     /locus_tag="VH957_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEQ8558333.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKK"
BASE COUNT        23478 a        12940 c        15771 g        22053 t
ORIGIN      
        1 cagttattaa taacatggca caagaggcct gccttatggt ataatggtaa agataatttc
       61 agaaagagga agccaagcat gtcttatgaa aaagaatttt taaaagattt tgaagactgg
      121 gttaaaactc agattcaagt caatcagcta gccatggcaa ccagtcaaga agttgcccaa
      181 gaagatggcg atgaaagggc taaagatgcc tttattcgtt atgaaagtaa gttagacgcc
      241 tacgaatttt tactaggtaa atttgacaat tataaaaatg gtaaagcctt tcacgatatt
      301 ccagatgagt tatttggagc aaggcattat taagaaggag acacgaaata gtggcaaaac
      361 aaaaaaatcg taaaaaagca ttgaaattag aaatgaagcg taatggcttg ttaaaaaaag
      421 caggtcaagt ttttgataag gcagttgaaa gtgttgaaac agctgtggat aaaaccattt
      481 ctgctggtaa aaatcttgtg gaaaaaggca gccaaacggt tgaaaacctg acagcaagca
      541 aggaaagact tactcttgat gagtttgcag ggcagccagt tgtagctggt atccgctctg
      601 accttgtcga aaccctatat gcagaaggca ttcattcagc gcaagctttt aaggagtgga
      661 cagaaaaaga cctccttgct cttaagggca ttggcccagc aacggttaaa aaattggtcg
      721 aaaatggcgc aagctttaaa aaatagtcat cttctcgttg cttaatggct ataaatttgt
      781 taaaatatta gcaatcagag gtgcattgag ttggtctgtt acagagagcg gtggtgttga
      841 gaaatccgca cagatgtcaa ggctagtagc tgaggatcag aaatcagata tgaaaagtag
      901 cagacccatt ttatggtttg aaacagtggt ggtaccgcgg aaatcgtaac acgaaattcg
      961 tccctgtcta ggttatctag gcagggatta tttggtttca tttgaaagaa gatgatggct
     1021 tattgttaaa atgttgttag aagtatataa tagaaaaact ttgcccaaag tggaaacaga
     1081 acggctgcta ttacgtcaac gaaaagggga caaggcattg ttccagaagc ggcttcagct
     1141 ctgattgaaa ttggttttac cttacttgat ttgcataaaa ttgagctggg ttgctacgac
     1201 tacaacaagc aaagtcaggc agtggctcgc aaattaggct ttaccttaga agccaatgcc
     1261 cgtgaccgta aggacgttca aggtcgccgc tgtggcgaca tgcgttttgg gttactgaga
     1321 agtgagtggg aggagcagaa acaaaaatga accttatcat cattggtgct caagcgtcgg
     1381 gcaagatgac cattgggcaa gaagttgcca ggcagacagg catgactttg tttcataatc
     1441 acgattctat tgactttgtt ttacggttta tgccttggtc tcaagagagc actgccttga
     1501 ttgaacgtat ccgttttgct ttttttgaaa cctttgctaa gacaggtcaa gacatgattt
     1561 ttactattgt aattgacttc aatgatccaa atgatgtagc aatgcttgaa aagattcagg
     1621 ctgtttttca gtcttatgac caagaggttc tctttgtcga attaaaaaca gatatagagg
     1681 aacgtcttaa acgcaatcgc acagaaaatc gtctcaaaca taaacctctt aaacgcaaca
     1741 tcgagtggtc agaacaagat attcaatcca cgatggcata tgctgttttt aatccagaag
     1801 aaccacccaa aacgctcacg cattaccaaa aaatcaataa tacccagctc accgctgctg
     1861 aaacagcgca gcttattatc caaaaaatga ctcatatcaa ggagaactaa gatgacagaa
     1921 ctatcaccta aatacaatcc tgccgaggtt gaggcaggtc gctatcaaaa atggcttgat
     1981 gcagatgttt tcaagccatc aggagaccaa aaagcaaaac cgtattctat cgtgattcca
     2041 ccgccaaatg tgactggtaa gttgcacttg ggacatgctt gggacacaac gcttcaagat
     2101 attatcattc gtcaaaaacg catgcagggc tttgatacgc tttggttgcc agggatggac
     2161 catgcaggga ttgcgacaca ggctaaagta gaggagcgtc tgcgcgagca ggggatttct
     2221 cgttacgacc ttggtcgtga caaattccta gacaaggtct gggagtggaa agacgaatat
     2281 gccactacga ttaaagagca gtggggcaaa atggggcttt ctgtggacta cagccgtgag
     2341 cgcttcaccc ttgatgaggg cttgtcaaaa gcagttcgca aggtttttgt tgacctctac
     2401 aaaaaaggct ggatttaccg tggtgaattc atcatcaact gggatcctgc tgccagaact
     2461 gccctttctg acatcgaggt tatccacaag gatgttgagg gagctttcta tcacatgaac
     2521 tatatgttgg aagatggctc acgcgccctt caagtggcaa caacgcgacc agaaaccatg
     2581 tttggagacg ttgccgttgc cgtaaatcca gaagatcctc gttacaaaga tttgattggc
     2641 aaaaatgtta ttttaccaat cgtgaataaa ttgattccaa tcgtgggtga cgagcatgcc
     2701 gatcctgaat ttgggactgg agttgtgaaa atcacgcctg cccatgatcc taacgacttc
     2761 gaggttggtc agcgtcataa cttaccacaa gtcaatgtca tgaacgatga cggtaccatg
     2821 aatgagttag ctggcgactt tgcaggcatg gaccgttttg aagctcgtca agctaccgtt
     2881 gctaaacttg aagaacttgg cgccctagta aacatcgaaa aatgtgttca ctcagtaggt
     2941 cactcagaac gttcaggtgc agccgttgag cctcgtctat ccacccaatg gtttgtaaaa
     3001 atggatgagc ttgctaaaca agctatggac aaccaagaaa cagatgaccg agtagatttc
     3061 tacccaccac gctttaatga taccttcctt caatggatgg aaaatgtcca tgactgggta
     3121 atctcgcgtc agctttggtg ggggcaccaa attcctgctt ggtacaatgc agaaggtgag
     3181 atttacgttg gcgaagaagc accagaaggt gatggctgga ctcaagatga agatgttctt
     3241 gacacttggt tctcatctgc tttatggccg ttctcaacta tggggtggcc tgacacagat
     3301 gtagaagatt tcaaacgtta tttcccaacc tcaaccttag taacaggtta tgacatcatt
     3361 ttcttctggg tgtcacgtat gattttccaa tcgcttgaat ttaccgggcg tcagccattc
     3421 caaaatgtcc tgattcacgg tcttattcgt gacgaagaag gacgcaaaat gtctaaatca
     3481 ttggggaacg ggattgatcc tatggatgtc attgagaagt acggtgccga tagcttacgt
     3541 tggttcctct caaacggctc tgccccagga caagacgtgc gtttctcata cgaaaaaatg
     3601 gacgcctctt ggaatttcat taataaaatt tggaacattt ctcgctatat cctcatgaat
     3661 aatgaagggt tgaccttgga agaagctgaa agtaatgtgg ctaaggtagc tgcctcagaa
     3721 gctggaaatg tgactgacca gtggattctc cacaatctca atgaaaccat cgctaaagtg
     3781 acagaaaact ttgacaagtt tgagtttggt gtggcaggac acattcttta caactttatt
     3841 tgggaagaat ttgccaactg gtatgtggaa ttgaccaagg aagtgctgta tagcgacaac
     3901 gaagctgaga aagttatcac gcgctctgtc cttctttata ctttggacaa aatcttgcgt
     3961 ctccttcacc caatcatgcc atttgtaacc gaagaaatct atgcccaata tgcccaaggt
     4021 tctattgtga ccgcagtata ccctacggtt actcctactt ttgaaaatga ggctgcgcat
     4081 aaaggtgtgg aaagtctgaa agatcttatc cgtgctgtac gaaatgcgcg cgctgaagtt
     4141 aacgtggcac catcaaaacc aatcaccatt ttggtgaaga cagcagatag tgagttggaa
     4201 gacttcttca ccagcaacgt gaactacatc aaacgtttca ccaatcctga aaaattagaa
     4261 atcagctcag ccattgctgc gccagagctg gctatgacca gcatcatcac aggtgctgaa
     4321 atctacttgc cactagcaga tttgcttaac gtggaagaag aactcgctcg cctagataaa
     4381 gaactggcta aatggcaaaa agaattggac atggtcggca aaaaactcgg aaacgaacgc
     4441 tttgtagcca acgccaaacc agaagtcgtc caaaaagaaa aagacaaaca agccgactac
     4501 caagccaaat acgacgcaac ccaagaacgg attgcagaga tgaagaaaat taaatcatag
     4561 tgtttagaac gcagttgaaa aactgtgttc ttttcttact aatagagata ttagattgaa
     4621 gtttaattat gagaaaaacg ctttctttat ttaaagagtt atgttacaat actattacaa
     4681 tcatcgtaca aatagtgtta ttttgagggg catatgagaa tgattttagc acactatgac
     4741 tgtaaaaaag ataaaaagca atctttagat gagcatttat ggcatgtggc ctgttctagt
     4801 cgacaggaag catctataat tggtcaagga gatgtgcttt ttttaattgg tctttaccac
     4861 gacctgggca aagctgatcg aacctttcaa gataaattat taaataatcc aaatcggcat
     4921 gttgatcact cttatgcagg ggcaaaatac ttatgttcta ttattgggcc tcatctaaaa
     4981 aaccgagggg ttgataaaaa tgagagaatg acattcaacg aaatggtggg gtatgtcatc
     5041 tctgctcatc atgggatgta tgatttatgc tactattttg acgatgctga atattatggc
     5101 tttaataagt ttaaaaatcg tatcaataga gacttagatg gttatcacta tcatgaagat
     5161 attaaagggt acgctctaaa attagaaaaa aaattatgtg attatggcta caaagattta
     5221 agggagctta ttgataaagc ttttgataat taccaacaag ccatgtcttc cttaaactgg
     5281 caagataaga gtgagtggaa ttattatcag tcttgtatgg tgagacttta cttgtcactc
     5341 ttaaaaaacg ctgatatttt ggacacagta aatgcctatg gccttaagat aagtcctatg
     5401 gataaaacag agcgatcctt tctaaaacac tcctatttag cggccattga acaaaaatat
     5461 gctagctttg gacagccaaa caatcagttg aacactattc ggacagaaat cgctgagcgt
     5521 gttaaagaaa gaggtaaacg agattccaag gggatttatc gcttagattt accgacagga
     5581 gctggcaaga ctaatcttag tatgcgttat gcgtttcacc aattagttca tcacgacaaa
     5641 tcaaggtttt tttacataac gccctttctt tcggttcttg agcaaaatgc ttccgaaatt
     5701 agaaaagtta caggtgacct tggcgttcta gaacaccatt ccaatgtggt gaaacaggct
     5761 aatgaagatg atgatgacaa ggacagttta ttgtcagctt atcttagtga tagctgggac
     5821 agtcaagtag tcttgacttc tatggttcaa tttttccaaa cacttttcaa aacaaaatca
     5881 gctaatctga gacgtttttc aagtttgatt aatagtattg tgattctaga tgaagttcaa
     5941 tccctgccta ttgaagtcac cactttgttt aatttaacga tgaatttttt aaataaagtt
     6001 atggatacaa ccatcgttct ttgcacagcg acacaacctg cttatgattc ttcagagatt
     6061 gaccatcgta tctgttatgg agggaacttg ggagaattag ctgaaatcgt tgagttaacg
     6121 attgaagaaa aacagatttt ttcaaggaca gagcttagaa aatttgatga tagtgatcag
     6181 aaagttcact tgactgatgt tattaacctt attctaggtg aggaaaactc cgttcttgct
     6241 atttttaata cgaaaaaaac ggttcataac tgctatacta tgctaaaaga catgactgat
     6301 agaccggtct atcagctttc gacaaatatg tgtgcgcagc atagacttga cttgattgct
     6361 aagatcaaaa cggagttaca aaataatatc cctattattt gtattagcac gcaattaatt
     6421 gaagcaggtg tagatgttga ttttcatcgc gtcattcgtt cctactcagg gattgattct
     6481 attgttcagg ctgctggacg gtgtaaccga gaaggcaaac gagataaagg gcaagtcact
     6541 cttgtcaatc tgaccaatga agaggaaaat atttctaggc tgacagaaat aaaagctaaa
     6601 aaagaagcca cagaatctat tcttcataag attgggtctc caattgatat ctcaacttta
     6661 aaccgtgact tttttgagta ttattatgcc aataatcagg gactgatgga ttatcctttg
     6721 gaagacaacc tatcaatcta cgactattta agccttaata tttatcagac ggcaaataaa
     6781 aagttcaaag gtaagttaaa acaagctttt aaaacagcag gagccaaaat gaacctcatc
     6841 aataatgata tgataggaat tctcgtacct tatggcgaag ctgagaaaaa attggcttat
     6901 ttagaagaat tgggtatgtc tcacttttta tcagcagaag attatcaaac gataaaatca
     6961 ttactaaaag agttacaacc ttttacggtt aatgtccgcg agaacgatcc tctctttgag
     7021 acaacaaaat cttatctaaa tggtcagatt ctggttttga cgtcggagta ttatgacacg
     7081 gaaagaggag ttaaatacga ttcagctagc ttttacttct aactcaaaac gaaagcagat
     7141 taacaaaagg ttgttagagg accttgttaa cctgccaatc atcattaata attattatca
     7201 atttagacta tttaataaaa ttagattaca aaaaaacaga aggaggaaag tagcttgtac
     7261 agatctagag acttctacgt gagagtaagt ggtcagcgag ctctttttac aaatccagcc
     7321 acaaaagggg gatcggaacg ctcatcctat tcggttccga ctagacaggc actgaatggt
     7381 atcgttgatg ccatctatta taagccgacc tttactaata tcgtcacaga ggttaaggtt
     7441 attaaccaga ttcaaaccga attacagggt gtcagggctc tgttgcatga ttatagtgca
     7501 gatttaagtt atgtatccta tttgagtgat gttgtttatc tgatcaagtt tcattttgtt
     7561 tggaatgaag atagaaaaga tttgaactca gatagacttc cagctaaaca tgaagccatt
     7621 atggagcgtt ctattcgtaa agggggacgt cgagatgtgt ttttgggtac aagagaatgt
     7681 ttagggcttg tagatgatat cagccaagaa gagtatgaga ctactgtgtc gtattataat
     7741 ggtgtcaata tcgacttggg aatcatgttc cattcctttg cctatccgaa ggacaaaaag
     7801 acaccattaa aatcatactt tacaaagact gtgatgaaaa atggagtcat tacgtttaaa
     7861 gcacagtctg aatgcgatat tgttaacacg ctttctagtt atgcttttaa agcaccagag
     7921 gagataaaat cggttaacga tgaatgcatg gagtatgatg ccatggagaa aggagaaaac
     7981 tgatggattt ttttacttct ctcttgaaga cttatgaaaa agcagagcta gcagacttgg
     8041 ttgatcacca aaaaagaagt aatgagtcgg ttttactgcc gatttatcat acgagtttaa
     8101 agtcaaatgg caaaaatatc atttcagtga aacttgacaa agatggccag tttcacaagg
     8161 cagaatttat ggcagataag caaatgatta tttttcctgt aacggctgat tctgttgcta
     8221 ggtcaggtag tcatcctgca ccgcatcccc tagtcgataa atttgcttat tatagtgctg
     8281 aaatggggca gactcagtat gattcttttc ataagcaact taataactgg attgattatt
     8341 gtgaggaggg tgacgtcaag aggtttttaa ccattgttca gcaatttatt ttgaaaccag
     8401 aatttctgac actgattctc gattctttaa ttggtcctga ttatcaaaat aatcaattaa
     8461 aagtcacatt ttgtgatgcc actggaaaag aaaaattaat tgatttatca gcttgctttt
     8521 tagaattttc aattgatcag ttccagggct ttaaaaatga atcggtttcg acatttaaaa
     8581 ctttacacca atcctatatt tcttttgttg aagccaatcg tgaaaagctt ggtatttgta
     8641 atattagtgg acgagaggaa cagctcaccg ataagcatag aggtttgatg gggaatacta
     8701 aaatcatctc tgttagtaat aaaagagaag cttataaagg acgttttaga gaacgcgaag
     8761 acgtttttag tgttggctat gaaacttccg aaaagattca tttaatgctc aagtaccttt
     8821 tagaaaataa aaataccagt acttggttag ggtcttctca atatttaatc aactggttta
     8881 gtgatgattt aacaaatgat agtcggttgg atatcgtatc accaatcttt gatgacggac
     8941 ttgaagaaga tgatgatgac gatacgcctc ctgttataac attagcaact gaagacaata
     9001 aaagaattgg taaatcattc atcaagggac aaaaattatt tgctaatgat gccacttact
     9061 acgttgctat tttgaataaa accagcaatg ggcggattgc tttaaaatat tttcgtcagc
     9121 ttcaagcgtc ccaattactc accaatctta acaagtggca ggaaacatac agttgggagt
     9181 cgcgatctaa gtttggaaaa agtcgcttaa gaacccctac ttttcatgac atccttaatg
     9241 tgtcctacgg ggttgatagg gatcgcttcc ttgaattaga taatgataac ttcaaaagtg
     9301 atcaaattca aaagttagtg gcaagtttga ttgatggtaa accgatgcca cagtccattg
     9361 tcaaaaagtt aggtaacaat gttaaagaac gacatcgtta ccataagcac tggtatcaag
     9421 ttgagcaggt ctgcttagca attttacaca aacaaaatgg ggaggaattt tcaccgatgc
     9481 tagatcatac caatcaaaat cgttcctatc tttttggacg attattagca atttttgaat
     9541 taatcgagac cttgcgttat ggcttggatg gaaacaataa cgaccgtatt accaatgctg
     9601 aacgttattg gacagcctat actggacaac caacaaaatt gatgatgtta ttggaaaata
     9661 aaattaagcc ttacgaagaa ccattgaaat taaatcgtcg tggcagttgg atgaaattag
     9721 aaaaagaaaa agaagagatt ttagaactgt taaatcctct gttagagaca gaaacaatgg
     9781 aaaaaccctt agattaccgc tttatttttg ggtattatgc tgagaaaaac tattactata
     9841 caaaacaaaa cactgaagta acagaaagtg aggagtaaaa agatgttgga acacaaaatt
     9901 gattttatgg taactcttga agtgaaagaa gcaaatgcaa atggtgatcc cttaaatgga
     9961 aatatgcctc gtacagatgc caaaggatat ggtgtgatga gtgatgtctc tatcaaacgt
    10021 aagattcgta atcgtctaca agatatgggg aaacctattt ttgtgcaagc taatgagcgt
    10081 attgaagatg actttcgttc actagaaaga cgcttttcgc aacattttac agctaagaca
    10141 cctgacaaag aaattgaaga aaaagcaaat gcattatggt ttgatgttcg tgcttttgga
    10201 caagttttta cttatctgaa aaaatcaatt ggggtgcgtg gaccagtttc catcagtatg
    10261 gctaagtcct tggagccaat tgtcatttcc agccttcaaa ttacgcgtag taccaatggt
    10321 atggaagcta agaataatag tggccgctct tctgatacga tggggacaaa acattttgta
    10381 gattatggtg tgtatgtact taaaggttct atcaatgctt attttgctga aaagactggt
    10441 ttttctcagg aagatgctga ggctattaaa gaagttttgg ttagcttgtt tgaaaatgat
    10501 gcgtcgtctg cacgtccgga aggctctatg cgagtttgtg aagtcttttg gtttacgcat
    10561 tcaagcaaac tggggaatgt ttcaagtgcg cgtgtctttg acttgttaga gtatcatcaa
    10621 tcaatagaag aaaaaagcac ttatgacgct tatcagattc atctaaatca agaaaaattg
    10681 gctaaatatg aagcgaaagg gttaacggtt gaaatcctag aaggactcta gtatggtcta
    10741 tgccgaagat gattatttaa tgctatcagg tattcagcat ttccaatttt gtaaacgtca
    10801 atgggcgttg atccatattg agcaacaatg gcttgataat gaagcgacag cgcatggaca
    10861 aattctacat actaaagcag ataatcctta cattaaagaa aaacgaaaag atcttttggt
    10921 ctcacgtgct atgcccattt cttctgcaga acttggactt tcaggaatta tggatgttgt
    10981 ggaattttat aaagatgatc aaggtgtgtc tttgagggga aaacgtggga aatggttacc
    11041 aaaagttgtg gaatacaagc gcggaaaacc taaaaaagat accagagata ttgtccagtt
    11101 ggtggctcag accatgtgtt tagaagaaac gctagactgc gacattaacg aaggttgtct
    11161 ttattaccat agtgtcaatc aaagagtgat tgttcctatg acatcagctt tgcgtcaaga
    11221 agtgaaggaa ttagccgcag agatgcatga ggtttatcag agtcaaatgc tacctaaagc
    11281 agcttatttt aaaaactgtc agctttgttc tttagtcgat atttgtaagc ccaggttgag
    11341 taaaaaaaca aggagtgtgt cgcgttacat caatgaggct atgaccagtg aggagatgga
    11401 cctatgaaga agttgctaaa taccttgtat ttgacgcaag aagattttta tgtcactaaa
    11461 gagggcgata acattgttat caagcaagaa ggtaaggttc tcaaacggtt tccgtttcgg
    11521 attattgacg gtattgtctg tttttcttat ttgggtgtgt cgcctgcttt ggtgaagtta
    11581 tgtacggaga atcagattaa tttatcgttt catacaccac aagggcgttt ttgtggtcgc
    11641 tatattggtt caaccaatgg gaatgtgttg ttgcgtagag aacattatcg tttatctgat
    11701 cgtgaggaat ctttggaata cgcaaagcgg tttattttgg ctaaaatttc caattcaagg
    11761 aaatacttgc tacgctttaa acgagatcat cgtcaacaga ttgataccaa gctttttgag
    11821 gctgttaatg acgaattgat atgggcttta gagatggttc aggcagcaga taataaagac
    11881 tctttaagag ggattgaagg ccaagctgct aatcagtatt ttcgcatatt taatgacctg
    11941 gtgttgacgg acaaaaaaac gttttacttc caaggtcgga gtaaacgacc acccttagat
    12001 tgtgttaatg ccctcttgtc ttttggttac agtttactga cctttgaatg tcaatctgcc
    12061 ttggaagctg tcggattaga cagttacgtt ggtttctttc acacggatcg tcctgggcgt
    12121 gctagtttag cgcttgattt agttgaagag ttccgctcat atattgtaga tcgttttgtc
    12181 ttttcattaa ttaataaagg acaacttcag aaaaaacact ttgaggttaa agaaaatggt
    12241 agtattttaa tgacggaaaa tggcagagct atttttattg atttgtggca gaagcgtaag
    12301 catactgagg tagaacatcc ttttacaaaa gagaaagtaa aacttatgtt attaccctat
    12361 gtacaagcgc agcttttagc taaggccata cgaggagatt tagaaagcta tccacctttt
    12421 atggtttagg agatgttata tgatggtttt agtcacttat gatgtaaata cggaaacacc
    12481 tgctggtaga aaaagattgc gtcatgttgc caaactctgt gtgaactatg gacaacgtgt
    12541 tcaaaattct gtttttgaat gttctgtgac acccgcagaa tttgtggata taaagcaccg
    12601 cttaacacaa atcattgatg agaaaactga tagtattcgc ttttatttat tggggaaaaa
    12661 ttggcagagg cgtgtggaaa cacttggtcg ctcagacagc tatgacccag ataaaggtgt
    12721 cttattattg taaaaatctc ttgtgcgaag ctagctttca cagaaacacc ttgcttgctc
    12781 gcgcaaaaat aacttaaaaa agaagcgaaa tggagataaa aaggcttaaa acacctctat
    12841 gtgtgccatc cgtttctcta taaactgtgt catttggcgc agtctcaccc ttcatgggtg
    12901 agtggattga aataagctaa acctatccta aaaatcaaag gcacagggtc tcacccttca
    12961 tgggtgagtg gattgaaata atgactatta tggggatatc tgccacgata tagtctcacc
    13021 cttcatgggt gagtggattg aaataccaat aattctaaag tcgctatctc tatctacggt
    13081 ctcacccttc atgggtgagt ggattgaaat ttataataca accaatagac ataatctaga
    13141 atcgtctcac ccttcatggg tgagtggatt gaaataaact atgtgactga cactctggac
    13201 tatgtcaaat acgtctcacc cttcatgggt gagtggattg aaattgctgt aggtaaagcc
    13261 gataataact ggggcggagt ctcacccttc atgggtgagt ggattgaaat aaaaaaatag
    13321 ctaagatcgc tactgtgtct gctgtctcac ccttcatggg tgagtggatt gaaatatgta
    13381 atcctgttgt taacttgtca aagtcataga gtctcaccct tcatgggtga gtggattgaa
    13441 ataaaaacaa atcgttatca atttgcgtct ttccagcgtc tcacccttca tgggtgagtg
    13501 gattgaaatg attcccccac gaagcaaaca agaattcaca gtcgtctcac ccttcatggg
    13561 tgagtggatt gaaatacgta aaatattaat cagtgttgat ttaccagtaa ccgtctcact
    13621 tttcatgggt gagtggattg aaataaattt ggcgaggaga gcgtgaggcg aatctagtgt
    13681 ctcacccttc atgggtgagt ggattgaaat attagcactg gttatattaa gtgccgagga
    13741 aaaagtctca cccttcatgg gtgagtggat tgaaagatga acccgacctc tcttttaatg
    13801 aggtcgggtt tttacatgcc tttagtcaac catttatctg atagcgtatc aaattcaagt
    13861 ttttgcatgt tctagtctat ggtttgcgcc actagctttc ggtaaactaa gagtaactta
    13921 agagaggagt tatttatgac actatcactt gtattaatgg tatcggtttt tggggcaggc
    13981 ttgttatcat ttttctctcc gtgtatcttt ccggtccttc ctgtctattt aggcatttta
    14041 ctggatgcag atgattcaaa gacgattact atatttggta aaaaactcta ttggtatggc
    14101 attgtcaaaa ccttagcctt tatttttggt ctatctacta tttttgtgat tttaggttac
    14161 ggggctggtt ttttaggaaa tatcttttat gcggtatggt ttcggtactt actgggagcc
    14221 ttggtcatta tcttggggat tcatcagatg ggcctcatta ccattaagag cttacaattt
    14281 caaaaatcac tgactttcca taataacaag aatcgcaacg gtttgttcaa tgcatttatc
    14341 cttggtttaa cctttagctt tggttggacg ccttgtgtgg gacctgtttt gagttctgtt
    14401 ctagctttgg tggcttcagg gggaaatggt gcctggcaag gtggcgtttt gatgattatt
    14461 tatactcttg gattgggcat tcctttcctg cttatctctt ttgcgtcagg cattgttttg
    14521 aaacagttta acaagctcaa accccacata cttttactga aaaaagtagg aggcgttctg
    14581 attatagtca tgggaatctt gcttatgaca ggaaccttaa ataacttagc acaacttttt
    14641 ggataaagga gaaacacaat gaaaaaagga ctattagtaa caactggttt ggcttgtctc
    14701 gggctactaa ctgcttgctc aacccaagac aatatggcta aaaaggaaat aactcaggac
    14761 aagatgagca tggcagctaa aaagaaagat aagatgtcaa catcaaagga caagtccatg
    14821 atggcagata aatcatctga taagaaaatg accaatgatg gtcctatggc gcctgatttc
    14881 gaactcaaag gcatcgatgg taaaacctat cgcttatcag aattcaaagg taaaaaagtt
    14941 tatttgaaat tttgggcctc ttggtgttca atctgtttat caaccttggc agataccgaa
    15001 gacctggcta aaatgtcaga taaagactat gtggtcttaa ccgtcgtctc gccaggtcat
    15061 caaggagaaa aatcagaagc agactttaaa aaatggttcc aaggaacaga ctataaggac
    15121 ttaccagtct tgttagatcc ggatggcaag ctattggaag cttacggcgt cagatcttac
    15181 ccaacagaag ttttcattgg aagtgatggt gttcttgcta aaaaacacat tggttatgcc
    15241 aaaaaatcag acatcaaaaa gacccttaaa ggtatacatt aggaaggacc agctgatagg
    15301 cattagaaaa aaggagttga gtttatggaa cacaaatgga aattatggct atttatcgtt
    15361 ggagtggtct ttttaatagg cggagcttct gttctcattc agaaaggtca agccaaggct
    15421 tttagtcaag gcaagcctca actaccagct aaaaaagtca aatccactaa agtagatccc
    15481 aatgcccctg ttgatcaaaa agtgatttac ctggctggag gctgtttctg gggcgttgaa
    15541 gaatattttt cacaagtgga tggcgttcta gatgcggtgt caggctatgc caatggtaga
    15601 ggcgatacca ccaactacca gttaattcat cagactggtc atgcagaaac cgttgaagtg
    15661 acctatgatg cgaaccgtat tagcttgaaa gaattattac tgcatttttt ccgaattatt
    15721 gacccaacca gtcttaataa gcaaggaaat gatcgcggta gtcaataccg aactgggatt
    15781 tactatactg acaaagcaga tttagctatt attgatgagg tcttcaaaga aaaagccaag
    15841 gattacaaga aaaaaatagt ggttgaaaaa gcaccattga aacactttat taaggcagaa
    15901 gactaccacc aagattacct caagaaaaat ccaaatggct actgccatat tgacatcaac
    15961 caagcgactt atcctgtgat tgatgaaagc aagtacccaa aaccaagtgc agctgagatc
    16021 aaagcaaaac tgtctgcaga cgagtaccga gtgacgcaaa aaaatgaaac tgaaaaagct
    16081 ttttctaatc gctactggga ttcttttgat gcaggaattt acgtagacgt tgtgacagga
    16141 gaaccacttt tctcttcaaa agacaaattt gaatcaggtt gtggttggcc aagttttagc
    16201 cgccccatca gcccagatgt tattcgttac aaggaagata agagtttcaa tatgacgaga
    16261 acagaggtgc gcagccgttc aggggattct catctggggc atgtctttac tgacggacct
    16321 aaagaccaag gcggccttcg ttactgcatc aatagcttgt ctattacctt tattccaaaa
    16381 gctgatatgg aagctaaggg ctatggttat ttattatcat ctgtagaata gggttaggcc
    16441 taaaaatctg atataataga agaaagacta gtatgagagg gccatgcaag gccctttata
    16501 aagataagga gacaccgtgt gtactcattg ttaattgtag aagacgaata ccttgtgcgc
    16561 cagggtattc gttctttggt tgattttagc cagttcaaga ttgatcgggt caacgaagca
    16621 gaaaatggcc agttggcttg ggacttgttt cagaaagagc cttatgatat tgttttgacg
    16681 gatatcaata tgcccaaatt aaatgggatt caactagcag aactcattaa acaggaatcc
    16741 ccccaaactc atctggtatt tttgacgggc tacgatgatt ttaactatgc cttatctgct
    16801 ttgaaattag gggcagatga ttacttgctc aaaccctttt ccaaggcaga tgtagaagac
    16861 atgttaggaa agctccggaa aaaattagaa ctttccaaga aaacagaaac cattcaggaa
    16921 ttggttgagc agcctcaaaa agaagtatca gcaatagcaa tggctattca tgagcggttg
    16981 gcagattctg atttgaccct aaaaagcttg gctcagcagc ttggttttag ccctaattac
    17041 cttagcgtct tgattaaaaa agagttaggg atgccctttc aagattatct gatacaagaa
    17101 cggttgaaaa aagccaagct tctcttgtta accagtaatc ttaaaatcta tgaaattgca
    17161 gagcaggtcg gttttgagga tatgaattat ttttctcagc gctttaagca actgataggc
    17221 gttaccccaa gtcagtataa aaaaggagac caggcatgaa gcgttatccc ctactggtcc
    17281 agttgatttc ttatatcttt gtgatcgtaa ttgccctcat taccacgctt ggtttgcttt
    17341 attaccagac gagttctcgt aatatcaggc aattaattga acgtgatact cggcagagca
    17401 ttcggcaaag ttcccaattt attgacgctt acatcaagcc tcttaaagaa acaacttcgg
    17461 tgctggcgaa aaatacggaa attcaagcct ttgctagtca aattcatcaa gaaaatgaca
    17521 agcaggtcct tcagctcatg aagatggttc ttgcgaccaa ttccgattta caagcagctg
    17581 ttctggtgac taaggatggt cgaacggtgt ctaccaattc tcagttgatt atgaaaacct
    17641 ccagtgatat gatggcagaa ccctggtata aagcagccat agaccgtcaa gccatgccaa
    17701 tcttaacccc agctcggcaa ttatcccttt cttctaaaaa agaatgggta gtttctgtga
    17761 cccaagaggt agtggatgct gctggtcata atttaggcgt gctaagactt gatattgcat
    17821 acccgaccat taaagcgtct ttagatcagc ttcagctagg ccgccaaggc tttgcattta
    17881 ttgtgaatga taagcatgaa tttgtttacc atcccaaaaa gagtgtttac agttcttcta
    17941 aggagatggc tgcgatgaag ccttatttgg ctattaaaaa tggctacgcc aaggataaat
    18001 catcctttgt ttatcaaagg gtcattccca acagtcaatg gactttgatt ggtgttgctt
    18061 ccttggacca attgcaccga gtacaacgtc agattttttg gtccttcctt gggatgggac
    18121 ttctagcctg tcttatttgt ggccttacga ctattttagt cttacgtaaa tggattcgtc
    18181 ccattcaaca attgcagcaa gttattcttg ctattcaaaa aggagatcgt cagttacgtg
    18241 cccaagaaac gggttctcca gaattgacag accttgccca acagtttaat gcgctcttag
    18301 atcaaattga tagcttgatg gttgccgttg cggataagga aaaggcgatt gggcagtata
    18361 ggttacaagc cttggctagt cagattaacc cgcattttct ctataacacc ttggacacta
    18421 ttatttggat ggcagaattt aatgacagca agcgcgtggt agaagtgacc aagtctctag
    18481 ctaagtattt tcgtttggcc cttaatcagg ggaacgaata cattcgtttg gcagatgaac
    18541 tggatcacgt tagccaatac ctctttattc aaaaacagcg ctatggagac aagctaagtt
    18601 atgacgttca aggcttagat gtctacgcag actttgttat tcctaagctt atcttacagc
    18661 ccttagtaga aaatgctatc taccatggca tcaaagaagt cgatcgcaaa ggcatgatca
    18721 aggttactgt atctgataca gctcagcatc tgatgttgac tgtttgggat aatggtaaag
    18781 gcattgaaga ctcttcactg accaatagtc agagcttgtt ggctagggga ggtgtgggcc
    18841 ttaaaaatgt tgaccagcgg ttaaaacttc actatggtga aggctaccac atgaccattc
    18901 atagccagtc agaccacttc actgaaatac aattaaccct tcctaaaatg catgagttaa
    18961 tggcagacga cacacaggaa aatgagtaag gttacaggaa gtgcatgtca gccatttccc
    19021 taagttaggg tattggagat aagaacctta gaaaggatat catgagttta gcatctgact
    19081 attttagccg acagaccccc atagttgaaa agctagtggc ttacggtttt gagaagcgag
    19141 acaacggtta tttctataat gaacggttta tggaaggaga atttgaggcg cagcttagga
    19201 ttgatgaggc tggcaatatc tgggatcggg ttattgattg tgatttggag gaggattatt
    19261 tgcctttaca acaagcagcc tggcaaggaa cctatactgg gcaggttaga gcagcctatt
    19321 tggaactctt ggggcgctta tcagtagcct gttttgaagt cactcctttt cagtcaatgc
    19381 aagctaatag acttgctaag catatcacca aagaatggtc tgacccaatg gactatcctt
    19441 ttgaaaagca cccagacctt gcaacctatc gggtaggggg caaatggtat gctatgattt
    19501 tttctctctt ggctgataaa ttagaccaga taccagagag attagtagga cagacatgtg
    19561 aagtgatgac tgtcaaagtt aatcccaagg ctttccctca gttactgcag caagaaggca
    19621 tttacccagc gtatcacatg tcaaagaaaa actggattag tattattttg gatgataagg
    19681 taacagatga taagctttgg acgttagtga ctcaaagtcg tcaactagtc aacccaaacg
    19741 gtctttctaa tcctaatggt cctgattatt gggttattcc agctaatttg aaatactatg
    19801 atattgatgc agaatttgca gccaatgatg tgattttatg gacccaaaaa gctggtattg
    19861 ccgtgggaga ctatgtgctg atttatataa cagccccagt caaatccatt cgctatgtct
    19921 gccaagttct agaaaccaat atacctaacg aaggctatcg taaaaatcct aacattgaca
    19981 aactcatgcg tctccgaaaa cgccaacagt acaaggatgg tctcttgtct tttgacctta
    20041 tgaaagaaca tggtgtagct gcagtgagag ggccaagacg attaagccct caattaattg
    20101 catttttaaa ggaaaaagag tattttaaag agaacaacta aaggagaata agagatggtt
    20161 gaatttgtag cagatcaaag tttttgggaa ctttttccag atgccaaact aggtgtcgtc
    20221 ttattaaagg atgttcagaa tcaagcagag tcaccagaag atgtcaaaca gctcttagca
    20281 gatagccatg agttagcaaa agcttattta acagcagaca attttagtga taatcaggtg
    20341 gttcaagtct accgcaaggc ctatcaacac tttaaaacca aaaaaggagc tcgctctagc
    20401 attgaagccc ttctcaagcg ggtgtcaaat ggtcaaagca ttccgtctat taacccacta
    20461 gtggatattt ataatgcggc tagtctacgt tttggtttac ctgttggagc cgaagatagt
    20521 gacagtttta tcggagattt gcgtctgacg ataacagatg gtggtgacga cttttacttg
    20581 attggggatg ctgacaataa cccaaccttg ccaaatgaac tgtgttataa agatgatatt
    20641 ggagcggttt gtcgttgcct taactggcga gatggcgaac gcaccatggt gacagaacac
    20701 accaaaaatg catttctgat tatcgaagct cttgatcaag aaggtcaaaa tagattgcaa
    20761 gaagctcttg acttcattga aggcagcgca aaaatgtacc ttcatgcaat cacttctgtg
    20821 catgtgttgg ataaagacaa tccacacgtg ctacttttta cagaaaacta gattagcagg
    20881 atgagctgtg taaaatagaa ggttaacaaa aaagcgagta aacgaatgtc ctgttcttta
    20941 ggttttcgtt tactcgcttt ttgatgagat cttactgctg ccctagcaaa aggtgaggat
    21001 gaggtcgtat atcacataga ggttttctgt taagccttat ttgttactaa agaagaatgg
    21061 tggtgtgtaa tgactaaggg tctcgtaaca agccttggct tgctcattgt cttcacagac
    21121 aatcaagcaa gtatcatcac cacagatcgt tgctacaatt tctggaattt gcatggcatc
    21181 taaaatggag ccaaaggatt gggctagtcc aggtaacgtt tttaaaataa tttgatgttg
    21241 aactatcttt aacatgacca aagcgtcttc catgtaaaaa cgaagacgat gttcccagcg
    21301 ggtttgtgaa atggctaacg cttcatagtg tgtgtcgttt ccagaagtta ctttgaccag
    21361 gttcaattcc ttcatgtcac gtgatagggt agcctgagtg atcgtgatgc catttttttg
    21421 caaccgttct tgtaattctt gctgtgtatg tatagttgtc tcagagatga gggaacgtat
    21481 gagttggtga cgcgtctctt tcttattcat tgttataatc ttcctttaac gtaattgata
    21541 acaatccgag tatagcaaaa agaggagaag gtgtaaagtt tttgatgaac cgcttacaaa
    21601 atggcttttt tatggtaaaa taaagatgat gtttagaaaa aggagatttg tgtgattcga
    21661 agagaagatt atcaatacct tagaaaacta aacgattttc gctacttttc tattgaacaa
    21721 tttgacaaaa ttgtagggca gatggaattc cgaaaagcta aaaaggacca tatccttttt
    21781 tttgagggag ataaaagaga taagcttttt ctagtgacct ctggttattt caaggtggag
    21841 cagtccgatc aatcaggaac cttcatgtat acggatttca tcagacacgg caccattttt
    21901 ccttacggtg gcctctttac agatgattat taccattttt cagtggtagc catgacagac
    21961 gtgacttatt tttactttcc agtcgattta tttgaagatt attcgcttga aaatcgtcta
    22021 caaatgaaac acttatatag taagatgtct aagctgctcg agttacatga gttgagggtc
    22081 cgaaacttga ttacatcaag tgctagttct cgtgtgattc aatctctggc gattttgctg
    22141 gttgaaatgg gtaaagacag tgatacctta ccttttcaat taacaacaac agatattgct
    22201 caaataagtg ggacgacaag agaaacagtt agccatgtgc ttagagattt gaagaagcaa
    22261 gaattgatta ccataaaagg taagtatttg acttatctag ataaagacta ttttttacaa
    22321 tacacaaagt gaattaaagg tcagaacact ttattttaaa agtttttctg acttatttta
    22381 atttataagt ataaattttt acactaagat gtaaaaaaca tacaagtaaa cgaatacaaa
    22441 tctataaaaa taaaaacaac gctcaaaaaa tgtaagcgat tactcaaaat agctgtgaga
    22501 aataccctat ttttatcttt tttaaggagt acactaggaa tataagcaag agttaagaat
    22561 cttgatggtg aattcacaaa aaccaattag aaagaggtaa ttcttatgac tgctcaaaca
    22621 ccaattcatg tttattctga aattggaaaa ttaaaaaaag tgttgctcca cagacccggt
    22681 aaagaaattg aaaatcttat gccagactac ttggaacgct tgttgtttga tgatattcca
    22741 ttcttagagg atgcccaaaa agaacatgat gcttttgccc aagctttgcg tgacgaaggt
    22801 attgaagtct tgtaccttga gaccttagct gcagaatctc ttgtcactcc agaaattcgc
    22861 gaagctttca tcgatgaata cctaagtgaa gctaatatcc gtggaagagc tactaaaaaa
    22921 gccattcgtg aattgttgat ggctatcgaa gacaatcaag aattgattga aaaaaccatg
    22981 gcaggagttc aaaaatctga acttccagag atcccagcat ctgaaaaagg cttgactgac
    23041 ttggttgaat ccaattaccc atttgccatc gacccaatgc caaaccttta tttcacacgg
    23101 gacccattcg caactatcgg tacaggtgtt tctcttaacc acatgttctc agaaacccgt
    23161 aaccgtgaaa ccctttatgg taaatacatt ttcactcatc acccaattta tggtggtggc
    23221 aaagtgccta tggtttatga ccgtaatgaa accactcgca ttgaaggtgg ggacgaactt
    23281 gttctttcaa aagatgtgct tgcggttggt atttctcaac gtacagatgc tgcttctatt
    23341 gaaaaattgt tggttaacat ctttaaacaa aaccttggct tcaagaaagt attggccttt
    23401 gaatttgcaa ataaccgtaa atttatgcac ttagacactg tctttaccat ggttgactat
    23461 gacaaattca ccattcaccc agaaattgaa ggcgatcttc gtgtttactc tgtcacttac
    23521 gacaatgaag aacttcatat tgttgaagaa aaaggtgatt tagcagaact tcttgctgct
    23581 aaccttggtg ttgaaaaagt tgaccttatc cgttgtggtg gtgacaactt agtagcagca
    23641 ggtcgtgaac aatggaacga tggttctaat accttgacca tcgcaccagg tgtggttgtg
    23701 gtttataacc gtaataccat taccaatgcc attcttgaat ctaaaggctt gaaattgatc
    23761 aagattcacg gaagtgaatt ggttcgcggt cgtggtggac ctcgttgtat gtcaatgcca
    23821 tttgaacgtg aagatattta ataagctatg gtaaaggtgg ttgtaggtca gaagcctttt
    23881 taaagggcag ctagtgttta tcttagcttc tgtgtctttg tccttcaatg aaattttgtc
    23941 atgacagata aatttgatgc caatgacgaa acaagaacgg tttatgcagt cgtttatgac
    24001 aatgaccagc ccgtttcaac aggacaattt ttagctgaaa cgaaaataga agcacgattg
    24061 acacgcattg taaccttagc agattattgt ggttgcggtt atggtgccaa agtcactgaa
    24121 gcgctagaaa cttataccag acgagaaggc ttttaccaac taaccattca cagtgaactg
    24181 acagcacaaa ccttttatga aaacctaggt tatcagtcct atggtcccaa gtgtttagaa
    24241 gatggtgagt attgtcagtc ccttgcaaaa accattctta aatgggagaa gaatatggac
    24301 atagcaatgc taattgcgat tgttggtggt ctattaggct gctatctcta tctcacaaaa
    24361 aataattaat caaaacagat tacagttaac actcgaagga gacaatagat gacacaagta
    24421 tttcaaggac gtagcttcct agcagaaaaa gattttacac gcgctgaatt agaatacctt
    24481 attgattttt cagcacattt gaaagatttg aaaaaacgtg gtgtgcctca tcactactta
    24541 gaaggtaaaa acattgccct cttgtttgaa aaaacatcaa ctcgtacgcg tgcagctttt
    24601 acaacagcag ccattgacct aggtgctcac ccagaatacc tcggtgccaa tgacatccaa
    24661 cttggtaaaa aagaatcaac agaagacact gctaaagtat tgggtcgtat gtttgatggg
    24721 attgaattcc gtggctttag ccaacgcatg gttgaagaat tggcagaatt ctcaggtgtg
    24781 ccagtttgga atggtttgac tgatgaatgg cacccaaccc aaatgcttgc tgactattta
    24841 acagtgaaag aaaactttgg caaacttgaa ggccttaccc ttgtttactg tggtgatggg
    24901 cgtaataacg ttgccaattc ccttcttgtg actggtgcta tccttggtgt taatgttcat
    24961 atcttctcac caaaagaact cttcccagaa gaagagattg tgacattggc tgaaggctat
    25021 gctaaagaaa gtggcgctcg tatccttatc acagaagatg ctgacgaagc tgttaaaggc
    25081 gcagacgtcc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcaaagaa
    25141 cgtgttgaat tgcttcaacc atatcaagtc aacatggacc ttgttcaaaa agcaggaaat
    25201 gacaagctta tcttcttgca ctgcttgcca gctttccatg acacaaacac cgtttatggt
    25261 aaagacgttg ctgaaaaatt cggcgtgaaa gaaatggaag tcactgatga agtcttccgc
    25321 agcaaatacg ctcgtcattt tgatcaagct gaaaaccgta tgcacactat caaagcggtt
    25381 atggcagcaa cccttggtaa cctctttatt ccaaaagtgt aataaggact ggtactcctt
    25441 aactcatttc acatatcaat gtgatccctt taatttaaca atttaactac ttaaaaacgt
    25501 actttaacta catgacaagt cgttctggtt ttcgcgtcct tgaccggaac tagaacggct
    25561 tatttttatg aaaaggtaag aggtaatcat tatgacagaa gaaaaaaaac ggggttttag
    25621 aattccttct tcttacaccg ttctttttat cattatagcc atcatggcag tgttaacttg
    25681 gtttattcca gctggcgcct acgaaaccgc taagggcggt ggtgttattt caggaaccta
    25741 caaaacagta gcatccaatc ctcaaggatt ttttgacatc ttgatggctc ccgttcgagg
    25801 catgttaggt gttgaaggca ctgatggtgc tattcaagtg tctttcttta tcttaatggt
    25861 tgggggcttt ttaggagttg tcaacaaaac aggtgctctt gacacaggaa ttgcgtcagt
    25921 ggttcgtaaa aacaaaggta gagaaaaaat gctgattgct attttaatcc ctttgtttgc
    25981 tctaggtgga acgacctatg gtatggggga agaaaccatg gccttttacc cacttttaat
    26041 tcctgttatg attgcggttg gttttgacag tattgttgct gtagccatta ttttgattgg
    26101 ttctcaaatt ggatgtctag cctccactat taacccattt gcaactggtg tagcagctga
    26161 tgctgctggt gtcagcattg cagatggaat gatttggcgt gttatccaat gggttattct
    26221 tgtcggcatg tctatttggt ttgtttacaa ttacgctagt aagattgaag aagacccaag
    26281 taaatcattg gttgcagata aggaagaaga gcataaggaa ctcttccagt tgcaaaattc
    26341 tggagaagac ttaaacaaac gccaacgaaa cgttttgacc atttttactt tgacctttgt
    26401 cattatgatt cttagtttga ttccgtggga agattttggt atcaaattct ttactaatat
    26461 caatacttgg ttaaccacaa tgcctatctt agggggagtt attgggaaaa ccatgggagc
    26521 atttggtact tggtatttcc cagaaatcac catgctcttt atcatgatgg gtgtcttagt
    26581 tgctattgtt tatcgtatga gtgaagaaga cttttttagc tcttttttga ctggtgcagg
    26641 tgaattttta ggtgttgcca tgatctgtgc tattgcacgc ggtattcaag ttatcatgaa
    26701 tggtggtatg attacagcca ctatcttaca cttaggtgaa acaagtcttt ctggtttatc
    26761 ttctcaagtt tttgtgatat tagcttatat tttctacctc ccaatgtcct tcttgattcc
    26821 atcaacatca ggacttgctg gggctacaat gggaattatg gcaccgcttg gacaattctc
    26881 aaatgtccct gctcaccttg ttattacagc cttccagtca gcttctggaa tcttaaacat
    26941 gatttctcca acttcagcaa tcgttatggg agcacttgcg cttggtcgcg ttgaccttgg
    27001 tacttggtgg aaattcattg gtaaatttat tgtaatggtg atgcttgtaa gcgtgctatt
    27061 acttgtagtt gcaacattct tttaacagat aggaggttcc tatggaatcc tatatcacac
    27121 ctaaacatca agaggcttgt gtagctgcca ttaaacagat cgtttcttac ccttctgttt
    27181 gtcatgaagg agaaaatggc acaccttttg gacaggccat tcaagatgtt ctcgaagcaa
    27241 ccttagactt atgtcaaggt cttggcttcc atacttatat tgatcctaaa ggttactatg
    27301 gttatgctga gttaggtgac caaaaagagg tcttggctat tctgtgccat ttggacgttg
    27361 ttccagaagg agatcgtcag ttatggaaga cagagccttt tgactgtgtt gaggcagacg
    27421 gctgtttatt tggtcgaggc actcaagacg ataaagggcc tactatgatg gcactatttg
    27481 ccaccaaagc cttgatagat gcaggcgtta cctttaataa acgcattcgt tttattttcg
    27541 gaacagatga agaaactttg tggcggtgta tgaatcgcta caatgatgta gaagaacagg
    27601 ctacctttgg gtttgctcct gattcaagtt tccctttaac ctatgccgaa aaaggcctac
    27661 ttcaggcaaa attagtgggg aaaggttctg ataaactgtc acttgaaatc ggacaagcct
    27721 acaatgttgt tcctgcaaga gcctcttatc aaggtgataa gcttgaggct ttacaaaaag
    27781 aactagataa gcttggcttt gagtacgtcg tcaaagaggg agaattaacg gtttatggtc
    27841 tcgcccaaca tgctaaagat gctcccgatg gcatcaacgc tatgattagg cttgccaaag
    27901 ctttagtggt ccttgaacct aacaaaaccc ttgattttct tgctaatgtc attgatgaag
    27961 atggcagagc acttaatatt tttggcagaa tcgaagatga accttcaggc aaattaagct
    28021 ttaatgccgc agggcttacc ttaaccaaag acaaggcaga aattcgccta gatattcgga
    28081 ttccagtttt ggcagataag gaaaaattag tccaacaatt aagccaaaaa gcacaagaat
    28141 acggcctaac ctatgaagaa tttgattatt tggctccatt atatgtgcca ttagacagtg
    28201 aattggtaac aaccttgtta tctgtctatc ggaaaaaaac aggtgatcaa agccctgccc
    28261 aatcatcagg aggggcaacc tttgctagaa caatgaagaa ttgtgttgcc tttggtgccc
    28321 ttttccctga tgctgctcaa acggaacacc aagaaaatga acatattgtt ttagcggatg
    28381 cttaccgcgc tatggatatt tatgcggaag ctatttaccg actaacgcga taacaagata
    28441 tgaggagtaa ttatgacgaa acaaaaaatc gtagtcgcac ttggaggaaa tgctattctt
    28501 tcaacagatg cgtcagcaaa agcacaacaa gaagccttga tttccacatc aaaatcattg
    28561 gttaaattaa ttaaagaagg tcatgaagtc atcgtgaccc acggcaatgg cccacaagtt
    28621 ggtaatctct tattacaaca agcagcggca gattctgaaa agaatccggc tatgcctttg
    28681 gatacttgtg ttgccatgac agaaggtagc atcggttttt ggttagttaa tgcccttgat
    28741 aatgaattgc aagcccaagg tattcaaaaa gaagtggcag ctgttgtcac tcaagtgatc
    28801 gtggatgcca aagacccagc ttttgaaaac ccaacaaaac caattggtcc atttcttacc
    28861 gaagaagatg ccaaaaaaca aatggcggag tctggtgcaa gtttcaaaga agatgcaggt
    28921 cgtggctggc gtaaggttgt gccatcacca aaaccagttg gtattaaaga agccaatgtc
    28981 atcagaagtc tcgttgattc tggcgttgtt gtggttagtg ctggtggtgg cggtgtgccc
    29041 gttgtggaag atgctactag caagaccctg actggtgtgg aagctgttat tgacaaggac
    29101 tttgctagtc aaaccctttc agaattggtg gacgcagacc tctttatcgt tttgacagga
    29161 gttgataatg tttacgtcaa cttcaacaaa cctgaccaag ccaaattgga agaagtgact
    29221 gtctctcaaa tgaaagaata catcacacaa gaccaatttg caccaggtag tatgttacca
    29281 aaagtggaag ctgccattgc ttttgttgaa aacaaaccaa atgccaaagc cattatcaca
    29341 tcgctagaaa atattgacaa tgtactatca gcaaacgctg gaacacaaat tatcgcaggg
    29401 taatcaagag gatttttagt tctgtttaaa agactcattt aatggtattt tctgaagagt
    29461 acgactgaca taaagagttg atactgtttt taaaggaaaa gagtgtgcca taataaaaaa
    29521 caataatagt attagaaaag gctaatttta ttgagaatta gccttttctt ttagctttga
    29581 taggtgtata ataaccatac tattttttat ttttcaaaat attagaataa acaaaagtgg
    29641 acaacgtata aagagaactg ctaagtcgtt gagctcatta gtcccaaaaa gattaccaaa
    29701 aaagaaggaa gaactatgaa gaaaagtttt attcatcaac aagaggagat ttcctttgtt
    29761 aagaatacgt tcactcagta tttgattgct aagttagatg ttgttgaagt gcaaggaccc
    29821 attttaagtc gggtcgggga cggtatgcaa gataatttgt ccggtactga aaatccagta
    29881 tctgtcaatg tcttgaaaat tcctaatgca acctttgaag ttgtgcattc attagcaaaa
    29941 tggaaacgtc acaccttagc ccgttttggg tttaatgaag gtgaaggcct tgttgttaat
    30001 atgaaggctc tccgacctga tgaggattca cttgaccaaa cccattctgt ctatgttgac
    30061 caatgggact gggaaaaagt catccctgat ggcaaacgta atctcgctta cctcaaagaa
    30121 accgttgaaa ccatttacaa ggtcattcgg ctaactgaat tagctgtaga agctcgttat
    30181 gatattgagg ctgttttacc taagaaaata accttcattc ataccgaaga attggtagct
    30241 aaataccctg atttgacgcc caaagaacgt gaaaatgcca ttactaaaga atttggagca
    30301 gtctttttaa ttggtattgg cggggtttta cctgatggta aaccacacga tggccgcgct
    30361 cctgactatg atgactggac aacagaaact gaaaatggct atcatgggct taatggtgat
    30421 attttggttt ggaatgacca acttggttca gcctttgaat tatcctcaat ggggatccgt
    30481 gtggatgaag aggccctaaa acgtcaggtg gaaatgactg gtgaccaaga ccgcttagcc
    30541 tttgattggc acaaatcttt gttgaatgga cttttccctc taacgattgg tggaggaatc
    30601 ggtcaatcac gtatggtcat gtttttgttg cgtaaaaaac atattggaga agttcagacc
    30661 tccgtttggc cccaagaagt tcgtgatagc tacgataata ttttataagt aatcacatca
    30721 ttttgctaag ttttccactt gtataagaga ctttaaataa atgatcagaa atattgaaaa
    30781 aagaaatcat ttttaaggtt tagagctaga aatttgctat aataaatgtt atgagagttg
    30841 tatcaggtga atttggtggg cgtcctttaa agacgctcga tggaaagata acacgcccta
    30901 cttcagacaa agttagaggt gcgattttta atatgatagg accttacttt aatggtggtc
    30961 gtgttttaga tttgtttgca ggttcaggtg gattagccat tgaggctgtt tctcgtggga
    31021 tgtctgctgc agttttggtt gagaagaatc gtaaagcgca agctattatt caagacaata
    31081 ttataatgac taaagctgag aatcggttta ccttgttaaa aatggaagct gagcgagcta
    31141 ttgattgctt gactggtcga tttgacttag tctttttaga ccctccttat gccaaagaaa
    31201 caattgtggc aactattgaa gctttagcag ctaaaaactt attgagtgaa caggttatgg
    31261 ttgtctgtga gacagataaa acagtcttgt tgccaaaaga gattgcaacg ttaggtattt
    31321 ggaaagaaaa aatttatgga attagtaagg taacagttta tgttaactaa aataggactt
    31381 tatacagggt catttgatcc tgttacaaac ggtcatctcg atattgttaa acgggcaagt
    31441 ggcctatttg atcaaatata tgttgggatt tttgataatc ctaccaaaaa aagctatttt
    31501 aaactagaag ttcgtaaagc aatgcttact caagctctgg ctgattttac aaatgtaatt
    31561 gtagtaactt cgcacgaacg tttagctatt gatgtagcta aagaattacg agtaactcac
    31621 ttgattagag gcttgcgaaa tgcaactgac tttgagtatg aagaaaattt ggaatatttt
    31681 aatcaccttt tagctccaaa tattgagacc gtctatttga tatcaagaaa taaatggcag
    31741 gcccttagct ctagtcgtgt gagagagcta attcattttc agtcttcctt agaaggtttg
    31801 gttcctcagt cagttattgc tcaagtggag aaaatgaatg aaaagactta aaaaaatcaa
    31861 atggtggtta gtgggtctgc tagctttaat ctctttattg ctagcgttat tttttccgct
    31921 accttattat attgaaatgc ctggaggcgc ttacgatatt cggactgtct tacaagtcaa
    31981 tggcaaagaa gacaaacgaa aaggagctta ccagtttgtt gcagtgggca ttagtcgtgc
    32041 cagcctcgcg cagctattat atgcttggct gacaccgttt actgaaatta gtacagcaga
    32101 agatacaaca ggcggataca gcgatgctga tttccttcga attaatcaat tctacatgga
    32161 aacatcacaa aatgcagcta tttatcaagc tttatcctta gctggaaaac cagttacatt
    32221 agattataaa ggcgtatatg ttttagacgt aaacaacgaa tctactttta aaggaacgtt
    32281 acacttagca gatactgtaa caggtgtaaa tggtaaacag tttactagtt cagcagaact
    32341 tattgactat gtttctcacc taaaactagg ggatgaagtt acggttcagt ttacgagtga
    32401 taataagcct aaaaaaggag ttggccgtat tatcaaactg aaaaatggga aaaatgggat
    32461 tggcattgcc ttgactgatc atacaagtgt caattcagaa gacacagtga tctttagtac
    32521 taaaggagta ggaggaccta gtgctggtct aatgtttact cttgatatat atgatcaaat
    32581 aactaaagaa gatttacgca agggccgtac aattgcaggt acaggaacta ttggcaagga
    32641 tggcgaagta ggagatattg gtggtgcagg tcttaaagta gttgcagcag ctgaagctgg
    32701 tgcagatata ttttttgttc cgaataatcc tgttgataag gaaattaaaa aagttaatcc
    32761 aaatgctata agtaattacg aagaagccaa acgggcagcc aaacgactaa agaccaaaat
    32821 gaagattgtt cctgttacga ctgttcaaga ggcactggtt tatcttcgca aataaaataa
    32881 ctatgaatgt attatattca attatattca attatattca cgctattaac tcataaaaaa
    32941 acggttgaac cagatagaca gatccttgac cagtcttttg ggttcaatca ttttttacat
    33001 aaaacataac taacttgaca gcgtaaaaaa gatgttataa aagtctagtg gtaaaaaggc
    33061 aatagagaat tgagtaaact ttagtcgatt atctggaaat agagcatact aaaaacacct
    33121 agtgaaaatt gatttttttc actaactcat ccaagaactt gcgcagataa tcatgagtcc
    33181 attccatgtc tctattattc aaagccttgc aatagacaag ttaacgttat aacaactaaa
    33241 ttaaaaactt gagattgaaa aatccccata aacttatttt acaaggaggt aaggctatgg
    33301 taaccattaa acaagttgct gaagaagcag gtgtttctag atcaacagtc tccaggtata
    33361 tttctcaaaa aggatatgta tctgatgatg caaggcataa aatcaaagca gcgatagcaa
    33421 aattacatta cactccaaat gtcttggcgc agtcattgaa gacgaaaaaa aatcaactag
    33481 tcggtttatt attaccagac atttccaatc ctttttttcc gaggttagca aggggagcag
    33541 aagaatattt aaaagaaaag gggtatcggg ttatgctagg aaatatttca gacagcgaag
    33601 ctcttgaaga agaatacgtc catgtccttc ttcaaagcaa tgctgctggc attattacta
    33661 cccatgactt tacaaagcgg tatcctactc ttgctattcc agttgtagtg gtagatcgtg
    33721 ttgaccaaga gacccagtac ggtgtctttt cagataatag ggcagggggc ttattggcgg
    33781 ctcagactgt ctggcaagca ggggcaaaag aagttttgtt aataagaggt ccgctggata
    33841 atgctgaaaa cattaatgag cggtttgaag ctagcttttc ttaccttcaa aaacaagacg
    33901 tgactacgta tgtgtgtgat agtcagaatt ttgattttga aagtattcag ctagaagcta
    33961 gttccaacct caagtgttac ccaacaatag acagtattat agcaccttct gatatccatg
    34021 ctattgctta tattcatgaa ctgcattctc aaggtaaaaa gattcctcaa gatgttcaaa
    34081 taataggtta tgatgacatt ttaatgagtc aatttattta tccttcttta tcgactattc
    34141 atcaatcctc ttatttgatg ggccgttatg ccgccgaatt agtttatact attgctagtc
    34201 aattaactgt gaaagcaaat cggattaaat tgcctgttca ctacgttgag cgagaaacaa
    34261 taaggaaaag ataagtaata atattagtcc agattttagc aggtatgatg aagatttatt
    34321 gggatttacc ttctacttta aaagatgtta tctgtcatta ctttcaccgc tatcagtcaa
    34381 aacgcattct tatgcaattc ttaaccttaa gcttaaggtc tttttgataa catagaggaa
    34441 tgttacacga cgatgacgca ataaagccta aatatagtaa ttgtcgtgat tttatagcta
    34501 gtgagtaatg agatagcaag tctctcattt acttacaaaa gtcaaaaaat agtgtataat
    34561 ggttgagtta cagataacac tgcaaaaaag ataacaagtg tccataatta tctaagacta
    34621 taaaggcgat atagacagat ataaaaaaga tgacgaatca gttatcactg gacaattaac
    34681 cgatttagtt acaactaatg gatttttcag aaaggtgtca aatgaaaaaa gaaatttcgc
    34741 cagaaatgta caactataat aaatttccag gtcccaaatt tattcatttt gaagagcaag
    34801 ttaaggctga aggcattgat ttgttactct tagaagatgt taagaacgct tttgatacga
    34861 ctagctttgg tcaacgttat acagaagttc tcctaaagta tgactatatt gttggcgatt
    34921 ggggaaatga acagcttcgt cttaaagggt tttataagga tagtgacgat atcaagaaaa
    34981 cgaatcgcat ctcacgttta gaagattata ttaaagaatt ttgcaatttt ggttgtgctt
    35041 attttgtttt agaaaatctt catccacaag atattaaatt tgaagaggag cgccaaccaa
    35101 gacgaaagaa atcacctaaa tcaaaatcaa atcgtcgcaa gccaaactat tcaaatcagc
    35161 agcccgcaac acctaagagt aaatcgaagc gggtatcaaa agaaaagcaa cctgaaaacc
    35221 aagcgtttac cagtcaaaaa cgtcgaagta atactaagca taaagaaaag tcaaaacgta
    35281 atcagactag tcaacttaat accaaaatta gtcattttat catcagaaag aaagataaat
    35341 aatccatgaa accatcgatt tatagcttaa cacgcgatga actgatcgcg tgggcagttg
    35401 aacgcggcca aaaacagttt agagctactc aaatttggga ttggctctat aaaaaaagag
    35461 ttcaatcttt tgaggagatg acgaatattt ctaaagattt tgtttctatt ttagatgata
    35521 gtttctgtgt caatccttta aaacagcgag ttgtacaaga atcagctgat ggtacagtaa
    35581 aatatttatt tgaactgccc gatggtatgt taattgaaac agttttaatg cgtcaacatt
    35641 atggtcattc tgtttgtgtg acgactcaag ttggctgtaa cattggctgt actttttgtg
    35701 ctagtggatt gatcaaaaag caacgtgatc taaacagtgg ggaaattaca gctcaaatca
    35761 tgttagtcca aaaatatttt gacgatagaa agcaaggtga gcgggttagc catgttgtcg
    35821 taatgggcat tggtgaacct tttgataact acaaaaatgt catgtgcttt cttcgcgtca
    35881 tcaacgatga taatggctta gcaattggtg cccgtcatat tacagtctct acctcagggt
    35941 tagctcacaa gattcgggat tttgcaaacg agggagtaca ggttaatcta gcagtctcgt
    36001 tgcatgcacc aaataatgat ttacgttcaa gtattatgcg agtaaatcgc tcttttccgc
    36061 tggaaaagct cttttcagct atagaatact atattgaaaa aacgaatcgt cgtgtcactt
    36121 ttgaatacat tatgctaaat gaagttaacg atagcattaa gcaagctcaa gaattagcag
    36181 acttaactaa aactattcgt aagttatctt atgttaactt gattccgtat aatcctgttt
    36241 cagaacatga tcagtatagt agaagtccta aagagcgagt tctagcgttt tatgatgtgc
    36301 taaagaaaaa tggagttaac tgtgtggtgc gtcaagagca cggaacagat attgatgcag
    36361 cctgtggcca gttacgttct aaaaccatga aaaaagatcg cgaaaaggtt acagcgacaa
    36421 aataaagccc aaaaaatatc tttgattgac aatgcttgat gacaaaatat tcctagtcac
    36481 taaaatgact aggtttttta tctggcctaa aaatgctcta gaagcacaat ccaaaataat
    36541 ccaaaactaa gataaggaat aaaaggtatg cgcttgatgc ctaatagtaa gcaagcagta
    36601 atacctgcta aactagcaag ttgaattagc caaatcaacg acgttagatc caatactaaa
    36661 gctaagctag caaggtagaa aaaatcgcct gctccaattg aaaaaggtct taaatgagct
    36721 aataaaccta gtagcagtaa tatcaatgat aaataattga tcgaataaaa caggagtaga
    36781 cttacaaagc taaaaagcca caagataaaa ggatattctt gagaacgcca atcaaataaa
    36841 ctaaataata aagaaaagag taacaagtaa cagtaactag cactaaccca atgtaccata
    36901 ctagcccata agataattat tagacttatc tctaagctaa agaagatttt ttggctagtt
    36961 ataaaatggt tttggagctg ccgaaaaacg cgtttggcaa aagttagttg gtcacaaaca
    37021 atgacagttt gtttacttag ctgttcttga ccattatcag gaaaataaag tagtaaacag
    37081 taaaaaagat gggtcaataa gatgcccgaa catatactaa aaaaagctat catacttatt
    37141 tattcgaaaa gaaatcaaat acttgcaatc tttccttaat cattgtagaa tatagatata
    37201 aaacgataat gattctaatt aagtatctaa tcatccaatt aggattattc cgttattgtc
    37261 gaataggatt aggtccttaa ccctttctta tgtttatcac gttagggtta gttccccctc
    37321 cattcttgcc ctttaagctg aaaagtaagg agatgttatt atgacaaaca cactcgttga
    37381 aaatatttat gcttcagtaa ctcacaatat ttctaaaaaa gaagcatcaa aaaatgaaaa
    37441 aactaaagct gttttaaacc aagctgtcgc tgacttatct gtggctgcat ctattgtgca
    37501 ccaagtacac tggtatatgc gtggtccagg tttcttgtac cttcacccaa aaatggatga
    37561 attacttgat agcttgaatg ctaatttaga tgaaatgagc gagcgtttga tcactattgg
    37621 cggagcgcct tattctaccc tagctgagtt ttctaaacac tctaaattgg acgaagcaaa
    37681 aggtacttac gataaaacag ttgctcagca tttagcaaga ttggttgaag tttaccttta
    37741 cctcagcagc ctttaccaag ttggtttgga tattaccgat gaagaaggcg atgctggaac
    37801 aaacgatttg tttacagcag ctaagacaga ggctgaaaaa accatttgga tgctccaagc
    37861 agagcgtgga caaggcccag cactctaatg gattatgcct taggataaaa gaagtcaatg
    37921 ataaaattgg cttctttttt atggaatcat cgattcattt tcagaaacat agaaagcgat
    37981 tccataattg tcttgaaatc tgccgtagaa tttgctaaaa tctacttata tgaaaacact
    38041 atatgatgtg caacaattgc taaaaaactt tggcattttt gtttaccttg gcaaacgtct
    38101 ctatgatatt gaaatgatga agattgaact tcagcgtctc tatgatagcg gcttattgga
    38161 taagagggat tacttaaatg cggagttaat tttgcgacgt gagcatagat tagaattgga
    38221 aaaagaagga tagacaaatg agtcaaaaat tactggggat tgatttaggt ggtaccacca
    38281 ttaaatttgg aattttaaca gcagcaggag aagtccaaga aaaatgggca attgagacta
    38341 atattttaga aggaggcaaa catattgtcc ctgatatcat cgcttccatc aaacatcgct
    38401 tagacttgta tggtctaagt agtgctgatt ttgtgggaat tggtatggga tcaccaggag
    38461 cggttgaccg tgatactaat acagttactg gggcattcaa ccttaattgg aaagaaaccc
    38521 aagaagtcgg ttccgttgtt gaaaaagaat tgggcattcc ttttgccatt gacaatgatg
    38581 ccaatgtggc tgcccttggt gaacgttggg taggtgctgg tgaaaataac ccagatgtcg
    38641 tcttcatgac acttggaaca ggtgttggtg gaggcattat tgctgatggt aacttgattc
    38701 atggtgttgc aggagcaggt ggtgaaatcg gccacatgat tgttgagcca gaaaatggct
    38761 ttgcttgtac ttgtggctca cacggctgtt tggaaacagt agcttcagca acaggagttg
    38821 tcaaagtggc acgtttactg gcagaagcct acgaagggga ttcagccatc aaagcagcta
    38881 ttgacaatgg tgaaggtgtt accagtaaag acattttcat ggcggctgaa gcaggggatt
    38941 cctttgctga ttctgttgtg gaaaaggttg gttactacct tggccttgct tcagcaaata
    39001 tttccaatat cttgaatcca gactcagtgg ttatcggtgg gggtgtgtca gcagcaggag
    39061 aatttctacg ctcacgtatt gaaaaatact ttgtgacctt cactttccca caagtgaggt
    39121 attcaactaa aattaagatt gcagagcttg gcaatgatgc tggaattatc ggtgcagcta
    39181 gccttgctcg acaatttatc acaaaatagg agggggatat gtctccaatc acacttatct
    39241 tatggttact tcttgtcggc attgttggtt attatacatg gaactatttc tcttttcgaa
    39301 aaatggcaaa gcaggttgat aacgagactt ttaaagacgt gatgcgtcaa ggtcaattga
    39361 ttgatttacg agagccagcg gcttttagag ctaagcatat tttaggagct cgaaattttt
    39421 cagcgcaaca atttgatgct gctatcaaag gtcttcgcaa ggacaaacct gttcttattt
    39481 acgaaaatat gcgtccccag taccgtgtgc ctgcggtcaa aaaacttaaa aaagctggct
    39541 ttgaagacgt ttatgtctta aaagacggta ttgattattg ggatggcaaa gttaaacaaa
    39601 caacctagtt aagagtaacg tggagttaag gggaataaag gcagtcactg tctcaaaaac
    39661 cttaattcct tttttgctgt atccagactt gctgaaagtc tgaaaacatt tacaattgat
    39721 taaaaccagt tttttaaaac attttgtgtt atacttatct agttaaaata tatttactta
    39781 gaggaacaaa tgactaactt aagaaacgat atccgtaacg tagcgattat tgcccacgtt
    39841 gaccacggaa aaacaacact tgtagatgaa ttattaaaac aatcccatac tcttgatgag
    39901 cgtaaagagc ttcaagagcg tgccatggat tccaatgacc ttgaaaaaga acgtgggatt
    39961 acaatccttg cgaaaaatac ggcagtagcc tataacgatg ttcgtattaa catcatggat
    40021 accccaggac acgcggactt cggtggtgaa gttgaacgta tcatgaaaat ggttgacggg
    40081 gttgttcttg ttgtggatgc ctacgaagga acaatgcccc aaacgcgttt cgtattgaaa
    40141 aaagcacttg agcaaaacct tatcccgatc gttgtggtga acaagattga caaaccttca
    40201 gctcgtccag cagaagttgt agatgaagtg cttgaattat tcatcgaact tggtgccgat
    40261 gatgagcaat tggaattccc agttgtttac gcatcagcta ttaatggcac atcatcatta
    40321 tcagatgatc ctgctgacca agagcatacc atggcaccta tctttgatac gattattgat
    40381 catattccag cgccagttga taattcagat gagcctttgc aattccaagt gtcacttttg
    40441 gattacaacg atttcgtagg tcgtatcggt atcggtcgtg tcttccgtgg tactgttaaa
    40501 gttggtgacc aagtaactct ttcaaaactt gatggtacca ctaaaaactt ccgtgttaca
    40561 aaactgtttg gtttcttcgg tttggaacgt cgtgaaattc aagaagctaa agcaggtgac
    40621 ttgattgctg tttcaggtat ggaagatatc tttgttggag aaaccattac accaactgat
    40681 tgtgtggaag ctctgccaat tcttcgtatt gatgagccaa cgcttcagat gactttcttg
    40741 gtcaataact ctccttttgc aggtcgtgaa ggtaaatgga tcacgtcacg taaggttgaa
    40801 gaacgtcttt tagcagaatt gcaaacagac gtgtcacttc gtgttgaccc aacagattcg
    40861 ccagataagt ggacggtttc agggcgtgga gaattgcact tgtcaattct tatcgaaacc
    40921 atgcgccgtg aaggctatga acttcaagta tcacgtccag aagttatcat caaagaaatt
    40981 gatggtgtca aatgtgaacc gtttgagcgt gttcaaattg atacaccaga agaatatcag
    41041 ggtgcaatca tccagtctct ttcagaacgt aaaggggata tgcttgatat gcagatggtt
    41101 ggtaatggtc aaacgcgttt gattttcttg attcctgcac gtggtttgat tggttattca
    41161 acagagtttc tttcaatgac acgtggatat ggtatcatga atcatacttt tgatcagtat
    41221 ctaccggttg ttcaaggaga aattggtggt cgtcatcgtg gtgccttggt ttctattgaa
    41281 aatgggaaag caacgacata ttcaatcatg cgtattgaag aacgtggaac tatctttgtc
    41341 aacccaggta cagaagttta cgaagggatg attgttggtg aaaactcacg tgataacgac
    41401 cttggtgtta acattacaac agctaagcaa atgacaaatg tccgttcagc gactaaagat
    41461 caaactgcag ttatcaagac gcctcgtatc ctaacgcttg aagaatcatt agagttcttg
    41521 aatgacgacg aatacatgga agtaacgcca gaatctatcc gcttgcgtaa acaaatcttg
    41581 aataaagctg cgcgtgataa agctaataaa aagaaaaaat cagccgaata gcttttgaag
    41641 ttaaactaac taaataaaat agcaaaaaga tatttaagaa aagtcatttt ttaaaggtct
    41701 ttttgcgttt acaagttcct atggaatata aaccaaaata aaggaggacg gaatgtttta
    41761 ccttattatg gctgtcttga ttatatctta ttatctatac atggctccta aaagtgtccg
    41821 taacaccctt gggatgattg gtttagttgg cttggttgct ctgcttattg ttttagcggg
    41881 cttgagtttt atcaaaatca tgcaaacccc tcctgaattt tttattggga tgggaatggt
    41941 ggcattgggc tattttgctt taaaagatgt gcgtaaaatg accaaaaaac cgagagttaa
    42001 ataaaagtac ttaaagattg atgattttgg tttttatacg ataaaaggac tgatttgttt
    42061 tagacaatat cagtcctttt ttaatagttc attttttctg aaagaaagct tttagccgat
    42121 tttcattgag tgtgcaacta aaaagagatg cttggtagtg acagttaaga cctctgacta
    42181 gtattttatc ttattttact taaaaaaacg taccaataat ctcacaaata tgggcatgat
    42241 gtttgtatat tggaaacgga ttctaattct aaactcaaga acggtatttt taaaatgttg
    42301 aaaaagcatc taaataaagg taaaatagaa atcaaataga atggatagtg tgagcttaga
    42361 tgaaagtgat aagtaatttt caaaacaaaa aaatattaat attggggtta gccaaatcag
    42421 gcgaagcagc agcaaaatta ttgactaaac ttggtgcttt agtgactgtt aatgatagta
    42481 aaccatttga ccaaaatcca gcggcacaag ccttgttgga agaggggatt aaggtcattt
    42541 gtggtagcca cccagtagaa ttattagatg aggactttga gtacatggtt aaaaaccctg
    42601 ggattcctta tgataatcct atggttaaac gcgcccttgc aaaggaaatt cccatcttga
    42661 ctgaagtaga attggcttat ttcgtatctg aagcccctat tatcgggatt acaggatcaa
    42721 acgggaagac aaccacaacg acaatgattg ccgatgtttt gaatgctggc gggcaatctg
    42781 cactcttatc tggaaacatt ggttatcctg cttcaaaagt tgttcaaaaa gcaattgctg
    42841 gtgatacttt ggtgatggaa ttgtcctctt ttcaattagt gggagtgaat gcttttcgcc
    42901 ctcatattgc tgtcatcact aatttaatgc cgactcatct ggactatcat ggcagttttg
    42961 aggattatgt tgctgctaaa tggatgattc aagctcagat gacagaatca gactacctta
    43021 ttttaaatgc taatcaagag atttcagcaa ttctagctaa gaccaccaaa gcaacagtga
    43081 ttcctttttc aactcaaaaa gtggttgatg gagcttatct gaaggatgga atactctatt
    43141 ttaaagaaca agcgattata gctgcaactg acttaggtgt cccaggtagc cacaacattg
    43201 aaaatgccct agcaactatt gcagttgcca agttatctgg tattgctgat gatattattg
    43261 cccagtgcct ttcacatttt ggaggcgtta aacatcgttt gcaacgggtt ggtcaaatta
    43321 aagatattac cttctacaat gacagtaagt caaccaatat tttagccact caaaaagctt
    43381 tatcaggttt tgataacagt cgcttgattt tgattgctgg cggtctagat cgtggcaatg
    43441 aatttgacga tttggtgcca gaccttttag gacttaagca gatgattatt ttgggagaat
    43501 ccgcagagcg tatgaagcga gctgctaaca aagcagaggt ctcttatctt gaagctagaa
    43561 atgtggcaga agcaacagag cttgctttta agctggccca aacaggcgat actatcttgc
    43621 ttagcccagc caatgctagc tgggatatgt attctaattt tgaggttcgt ggggatgaat
    43681 ttttggcaac ctttgattgt ttaagaggag atgcctaatg cctaagaaga ttttatttac
    43741 aggtggtgga actgtaggtc atgtcacctt gaacctcatt ctcataccaa aatttatcaa
    43801 ggacggttgg gaagtacatt atattggtga taaaaatggc attgaacata cagaaattga
    43861 aaagtcaggc cttgacgtga cctttcatgc tatcgcgaca ggcaagctta gacgctattt
    43921 ttcatggcaa aatctagctg atgtttttaa ggttgcactt ggcctcctac agtctctctt
    43981 tattcttgcc aagcttcgcc ctcaagccct tttttccaaa ggtggttttg tctcagtacc
    44041 gccagttgtg gctgctaaat tgcttggtaa accagtcttt attcatgaat cagatcggtc
    44101 aatgggacta gcaaacaaga ttgcctacaa atttgcaact accatgtata ccacttttga
    44161 gcaggaagac cagttgtcta aagttaaaca ccttggagcg gtgacaaagg ttttcaaaga
    44221 tgccaaccaa atgcctgaat caactcagtt agaggcggtg aaagagtatt ttagtagaga
    44281 cctaaaaacc ctcttgttta ttggtggttc ggcaggggcg catgtgttta atcagtttat
    44341 tagtgatcat ccagaattga agcaacgtta taatatcatc aatattacag gagaccctca
    44401 ccttaatgaa ttgagttctc atctgtatcg agtagattat gttaccgatc tctaccaacc
    44461 tttgatggcg atggctgacc ttgtagtgac aagagggggc tctaatacac tttttgagct
    44521 actggcaatg gctaagctac acctcatcgt tcctcttggt aaagaagcta gccgtggcga
    44581 tcagttagaa aatgccactt attttgagaa gaggggctac gctaaacaat tacaggaacc
    44641 tgatttaact ttgcataatt ttgatcaggc aatggctgat ttgtttgaac atcaggctga
    44701 ttatgaggct actatgttgg caactaagga gattcagtca ccggacttct tttatgacct
    44761 tttgagagct gatattagct ccgcgattaa ggagaagtaa atggcaaaag ataaagagaa
    44821 acaaagtgat gacaagctcg ttttgacaga gtggcaaaag cgtaacattg aatttttaaa
    44881 gaaaaagaag cagcaagctg aggaagaaaa aaaactcaaa gagaaattat tgagtgataa
    44941 aaaagcgcag cagcaagctc aaaatgcttc tgaagcagtt gagcttaaaa ctgatgagaa
    45001 aactgatagt caggaaattg agtcagaaac gacgtcaaaa cctaaaaaaa ccaaaaaagt
    45061 tagacaaccc aaggaaaaaa gcgcgacaca aatcgctttt caaaaatcct tgcctgttct
    45121 tttgggggcg ctcttactca tggcggtgtc tatttttatg atcactcctt atagcaaaaa
    45181 gaaagagttt tctgtaagag gaaaccatca aacgaacctt gacgaattaa tcaaagctag
    45241 caaagtcaaa gcatctgact attggttaac gttgttaatt tcgcctggtc agtatgaacg
    45301 accgattctt cgtactattc catgggtgaa atctgtacat ctctcttacc aatttcctaa
    45361 tcactttcta tttaacgtta ttgaatttga aatcatcgct tatgcacaag tcgaaaacgg
    45421 ttttcagcct attttggaga atggaaaacg tgtggacaag gtcagggcat cagaactacc
    45481 gaaatctttc ttgattctta atttaaaaga tgagaaagcg atccaacagt tagttaagca
    45541 attaacgaca ttacctaaaa aattagtcaa gaatatcaag tcagtgtctc ttgcaaattc
    45601 caaaacgaca gcggatttac tacttattga aatgtatgac ggtaatgtag ttagagtacc
    45661 gcagtcacaa ctcacattga aacttcccta ttatcaaaaa ttgaaaaaaa accttgaaaa
    45721 tgatagtata gtggatatgg aagttggaat ttatactaca acacaggaga ttgaaaatca
    45781 acctgaagtt cctcttacgc cagaacaaaa cgcagctgat aaagaaggag ataagcctgg
    45841 tgaacatcag gaacagacag acaatgattc agaaacgcca gcaaatcaga gtagtcctca
    45901 gcaagcacca ccatccccag aaacggtcct cgaacaggcc catggctagc taatatctaa
    45961 gttgaaaaag caatgaaaac gttagaaatt caacgattct aacccataat gaattgccta
    46021 aaaaaattaa gtttatataa caaaaaacgt aaaatgataa cattttacgt ttttttatgg
    46081 tataatattt tctgaatgat tctgtttttt agcagttttt agaatagcaa aagtttggaa
    46141 agtaagtgag gtcaagtgaa tggctagaaa tggctttttt actggtttgg acattggaac
    46201 aagctcgata aaagttttag tagcagaatt tatttctggt gagatgaacg tcattggtgt
    46261 tagtaatgtt ccaagtaccg gcgtaaaaga tggcataata atcgatatag aggcagctgc
    46321 gactgccatc aaaactgcgg tagaacaagc agaagaaaaa gcagggatga caattgaaaa
    46381 ggttaatgtt gggctaccgg caaaccttct tcaaattgaa ccaacacaag gaatgattcc
    46441 tgtcccaagt gagtctaaag agataaaaga tgaggatgtt gatagcgttg ttaaatcggc
    46501 tttaacaaaa agtatcacac cagaacgaga ggttatctct ttagttccag aagagttcat
    46561 tgtggatggc tttcagggca ttcgagatcc acgtggtatg atggggatta ggttagagat
    46621 gcgcgggctt atttatactg gaccaagcac cattttacat aatctgcgta aaacggtaga
    46681 aagagcaggc attaaagttg aaaacatcat tatttctccg ttagctatgg ctaaaaccat
    46741 tttaaacgaa ggtgagcgcg agtttggagc tactgtaatt gatatgggag gtggacagac
    46801 aactgtcgct tctatgcgag cacaagaatt gcagtatacc aatatatatg ccgaaggcgg
    46861 cgaatacatt actaaagata tatcaaaagt attaaaaacg tctttggcta ttgcagaagc
    46921 acttaagttt aattttggtc aagcggagat atcagaagct agtataactg aaacagtaaa
    46981 agttgatgtg gtaggtagtg aagagcctgt tgaggtaact gaacgttatt tatctgaaat
    47041 tatttcagcg cgtattcgtc atattttaga tcgtgtgaag caagatttgg aaagaggtcg
    47101 tttactagac ttaccaggag gcattgtttt gattggtggc ggtgcaatca tgcctggagt
    47161 ggtagaaatt gcacaagaaa tctttggagt aactgtaaag ctccatgttc caaatcaagt
    47221 cggtattaga aatccaatgt tttcaaacgt tatcagtttg gtagaatatg ttggtatgat
    47281 gtctgaagta gacgttttag cacaaactgc agtttcagga gaagaacttt tgcgacgcaa
    47341 gcctatcgat ttcagtggtc aagaatctta tttaccagat tatgatgatt caagaagacc
    47401 agaatcgacc attggctatg aacaacaagc gtcacaaaca gcatatgatt cacaagttcc
    47461 gagtgatcct aaacaaaaaa tttcagaacg tgttcgtggc atatttggga gtatgtttga
    47521 ttaaaagtaa taaagtgagg aaataaaatg gcattttcat ttgatactgc atcaattcaa
    47581 ggtgcaatta taaaagtaat tggagtcggc ggaggtggcg gaaatgccat taatcgtatg
    47641 attgatgaag gtgttgctgg tgttgagttc atcgcagcaa atacagacat tcaggcatta
    47701 agctcatcaa aagctgaaac ggttattcaa ctaggcccta aattaactcg tggacttggt
    47761 gctggaggac aacctgaagt aggacgtaaa gctgctgaag aaagcgaaga aattttaaca
    47821 gaagctctta caggagcgga catggtattt attactgccg gtatgggtgg tggctctggg
    47881 acaggggctg caccggttat tgctcgtatc gctaaaagtt tgggagcctt gacagtagct
    47941 gttgttactc gcccgtttgg ttttgaaggt aacaaacgtg gtaattttgc tattgaaggt
    48001 atcgaagaac tacgtgaaca agttgatact ttgttaatta tttcaaataa taaccttctt
    48061 gagattgttg ataaaaagac acctttatta gaagcactta gtgaagctga taatgtttta
    48121 cgtcagggag ttcaagggat aaccgactta attactagtc ctggccttat caatctcgat
    48181 tttgccgacg tgaaaacagt tatggcaaat aaagggaatg ccttgatggg gattgggatt
    48241 ggttctggag aagagcgcat tgttgaggcg gcgcgtaagg caatatattc acccctatta
    48301 gaaacgacta ttgatggtgc acaagacgtt attgtgaacg ttacaggagg tctcgacatg
    48361 acacttacag aagctgaaga agcctctgaa attgttgggc aagctgctgg tcaaggcgtt
    48421 aacatttggt taggaacatc tattgatgat actatgaaag atgacatccg tgtgactgtc
    48481 gtagcaactg gagtgcgcca agaaaaagcc gaacaagttt caggttttcg tcagcctagg
    48541 acttttaccc aaaccaacgc gcagcaagta gcgggtgcac aatatgcatc agatcaagca
    48601 aaacagtcgg ttcaaccagg gtttgatcgt cgctcaaatt ttgattttga catgggggag
    48661 tctcgcgaga taccaagtgc acaaaaggta atttctaatc ataatcaaaa tcaaggttca
    48721 gcttttggaa attgggattt gagacgtgat aatatttctc gtccaacaga aggtgaatta
    48781 gataaccatc ttaatatgtc aacgttctca gctaacgatg acagtgatga tgaattagaa
    48841 acgcctccat tctttaaaaa ccgttaataa tggatttact gacaaataaa aagaagattt
    48901 ttgagactat ccgcttatct acagaggcag caaataggac taatgatagt gtttcagtta
    48961 ttgctgtaac aaaatatgtg gatagtacaa ttgcaggtca gcttatcgaa gcaggaattg
    49021 agcacattgc cgaaaaccgt gttgataaat ttcttgaaaa gtatgatgcg ttaaagtata
    49081 tgccagtaaa gtggcattta atcggtacct tacaacgtcg taaggttaag gaagttatca
    49141 attatgttga ttattttcac gctctagatt ctgtgagatt agctttggaa atcaacaaga
    49201 gagctgacca tcctgtgaag tgttttctac aagttaatat ttctaaagaa gagagtaaac
    49261 atggttttaa catttctgag attgatgaag cgattgaaga aataggtaag atggagaaga
    49321 tacagttagt tggtttaatg actatggcac cagcaaatgc cagtaaagaa agtattataa
    49381 ctatttttcg acaagcaaat caattaagaa aaaacttgca gttaaaaaaa gaaagaatat
    49441 gccttttaca gaattgagca tgggcatgag taacgattat ccaattgcta ttcaagaagg
    49501 ctcaactttt attcggattg gtagagcttt ctttcactaa tggagaataa gatggctttt
    49561 aaagatacat ttaacaagat gatttcttat tttgacacgg atgaggttaa cgaagttgaa
    49621 gaagatgttg cagcatcaac tgataacgtt attccaagat cacaacaatc agtcagagca
    49681 agtagtcatc caaaacaaga acctagaaac aatcacgtac aacaagatca tcaagcgaga
    49741 tcccaagaac agacaaggtc acaaatgcat ccaaaacatg gtacttctga acgctattat
    49801 cagcagtctc agccaaaaga aggccatgaa atggttgaca gaagaaaacg gatgagcact
    49861 tctggtattg caaatcgccg tgagcagtat caacaatcaa cttgttcaga tcaaacaact
    49921 attgccttaa aatatcctcg taaatatgag gatgctcaag aaattgtgga tcttttaata
    49981 gttaatgaat gcgttttgat tgattttcag tttatgctag atgctcaggc tagacggtgt
    50041 ttagatttta ttgatggtgc tagtaaagtg ctctatggta gcttacaaaa ggtcggctct
    50101 tcaatgtact tactggctcc gtcaaatgta tccgtcaata tagaagaaat gactatccca
    50161 catactacac aagatattgg ctttgatttt gatatgaaaa ggcggtaaat aaatgatatt
    50221 aatactatct attcttcttc gtctgatcaa agtttacact tatttattga ttgcttacgc
    50281 attaatgtca tggtttcctg gggcatatga ttcaaaaatt gggcgtttga ttagtggtat
    50341 cgttgaacca attttaaaac cttttagagc atttaattta caatttgcag gtcttgactt
    50401 cactattttt gtcgtcatta ttagtttgaa ttttttagct caagttttgg tccgtgtgtt
    50461 tatttaatgg ttagtcatag taagatttat cagcattttc accaagaaga atatcctttt
    50521 attgatagaa tgtctgatat gattaataga gttgaagatt actatctttt agaagttact
    50581 gagtttttaa atcctagaga agtgatgatt ttaaaaagtt tgattgcttt aacagatcta
    50641 aaaatgttcg tatcaacaga ttactaccca agcgaatatg gtcgtgtcat tattgcacct
    50701 ggttactatg acttagaaca aagtgatttt caaatagctt tagtagagat aagttatcag
    50761 gcaaagttta atcagttgac acatagtcaa attttaggaa ctttaattaa tgaattagga
    50821 gtaaagcgaa atttatttgg agatgttttt gttgaaatgg gatatgccca gctcatgatt
    50881 aagcgggagt tattggatta ttttttagga acaattacta aaatagctaa aactagtgtg
    50941 aaattaagag aagttaactt tgatcagtta attaggtcta ttgataacag ccagaccctg
    51001 gatattctag tttctagttt tcgattagat ggtgtagttg ctactatctt aaaaaaatct
    51061 cgaacgcaag ttatagcatt aattgaagca aataagatta aggtaaacta tcgactcgct
    51121 aataaagctt cagataatct agtcataggg gatatggtga gtatcagagg tcacgggcgt
    51181 tttactcttt tagcagataa tggagtgacc aaacatggca aacaaaaaat aacactaagt
    51241 aaaatgatac ataaataagg agatacaatg gcacttacaa cgctagaaat taaagataaa
    51301 acttttaaga caaaattccg aggatactgt gaagaagaag tcaatgaatt ccttgatatt
    51361 gttgttgatg attacgaagc tcttgtacgt aaaaatcgtg ataacgaagc aagaattaaa
    51421 gatcttgaag aaaaattatc ttactttgat gaaatgaaag agtcacttag ccagtctgta
    51481 atcttagctc aagaaacagc tgaaaaagtg aaagcaacgg ctaatgcgga agcaacaaac
    51541 ttggttagta aagcgactta tgatgctcag catttattag atgaatctaa agctaaagcc
    51601 aatcaaatgt tgcgtgatgc aactgatgag gctaagcgag ttgcgattga aacagaagaa
    51661 ctaaagcgtc aaacacgtgt gttccaccaa cgtttaatct catctattga gtcacaatta
    51721 agcttatcaa attcacctga atgggatgaa ctgctacaac cgactgcaat ctatcttcaa
    51781 aattctgacg atgcttttaa ggaagtcgtg aagaccgttc ttaatgaaga cattcctgaa
    51841 tctgatgata gtgcctcttt tgatgcaaca cgtcagttta ctccagaaga gttagaagaa
    51901 ttgcaacgtc gtgttgatga aagcaataag gagttagagg cttaccaact tgactctcaa
    51961 tctgattcta tgactgagcc agaggtaaat ctcagtgaaa cacaaacgtt taaattaaat
    52021 atctaaataa agaaaaacaa gatgatttgc ttataatcac agcaagcggg agatgatgag
    52081 agtctcgtat tccctaagta ttatcattat cattttctaa aattttcgct gaactacagt
    52141 aagcgaggag gtttgttcac cttacgagca aagagggagc ggtaagtctt atgatatatt
    52201 atcgctctga actaaggtgg taccacgagc tttcgtcctt tttgagacga ggcttttttc
    52261 gttatagtcg caagtttgtt taaaaggagt ttgaaataat gaaattaaaa gagacactta
    52321 atctaggaaa aacagccttt ccaatgcgcg caggtcttcc taataaagag ccacaatggc
    52381 aagcagcttg ggaacaagca gagctttaca aaaaacgtca agaatcgaat gcaggtaagc
    52441 ctgcctttca tcttcatgat ggacctccat acgctaacgg caatattcac gttgggcatg
    52501 cccttaataa aatttcaaaa gatatcattg tgcgttctaa gtccatgtct ggctttcaag
    52561 cgccttatgt acctggttgg gacacacacg gccttccaat cgaacaagtc ttggctaagc
    52621 aaggaatcaa acgtaaggag atggatttag cagaatacct tgagatgtgt cgtcaatacg
    52681 ctttaagtca ggttgataaa cagcgaaatg atttcaaacg gttaggtgtt tcggcagact
    52741 gggaaaatcc ttatgtcact ttggacccac agtttgaagc tgatcaaatt cgtgtttttg
    52801 gagcgatggc tgaaaaaggt tacatctatc gtggtgctaa acctgtttat tggtcatggt
    52861 cttcagaatc ggccttggca gaagctgaaa ttgaatacca tgacatcgat tcaacctctt
    52921 tatactacgc caataaagtt aaagatggta aaggcatcct tgatactaat acgtatatcg
    52981 ttgtttggac aacaacacca tttacggtta cagcatcacg cggtttgact gttgggcctg
    53041 atatggatta tcttgtggtg aaacctgctg gttcagaccg tcaatatgtt gtggcagaag
    53101 gtcttttgga tagccttgct ggaaaatttg gctgggaatc ttttgaaact ttagccagcc
    53161 ataaaggagc tgatttagag tacattgtga cagaacaccc atgggatact gacgtagaag
    53221 aattggttat ccttggtgac catgttaccc ttgagtcagg gacagggatt gtccacacag
    53281 caccaggttt tggtgaggat gactacaatg ttgggacaaa atacaaactg gaagttgctg
    53341 tgactgttga tgaacgtggc ctaatgatgg aaaatgcagg tccagatttc cacggacaat
    53401 tttataacaa ggtaacgccg attgtcattg ataaacttgg tgatctttta ttggcacaag
    53461 aagtgatcaa tcactcttac ccatttgact ggcggacgaa aaaaccaatc atctggcgtg
    53521 ctgtaccgca atggtttgct tctgtttctg atttccgtca agatattttg gatgaaattg
    53581 aaaaaacaac cttccatcca tcatggggtg aaacacgcct ttacaatatg attcgtgatc
    53641 gtggcgactg ggttatttct cgtcaacgtg cttggggagt tccgcttcct atcttctatg
    53701 ccgaagatgg cacagctatt atgactaaag aagtgacaga tcatgtggct gatttgttcc
    53761 aagaaaatgg atcaatcatt tggtggcaaa aagaagctaa agacctatta ccagagggct
    53821 tcactcatcc agggtcacca aatggcgagt ttacaaaaga aactgatatc atggacgttt
    53881 ggtttgactc tggttcttct tggaatggag tcatgaatac taaagaaaat ctttcctatc
    53941 cagcggatct ctacttagaa ggctctgacc agtatcgtgg ttggttcaat tcatccttaa
    54001 ttacatctgt ggctgttaat gggcatgctc catataaggc tattttatcg caaggctttg
    54061 ttcttgatgg taagggcgaa aaaatgtcta aatcaaaagg caatatcatt tctcctaatg
    54121 atgtggctaa acaatatggt gcagatattc ttcgactttg ggtagcttct gtggataccg
    54181 ataatgatgt ccgtgtttct atggagatcc ttggtcaagt ctctgaaact taccgtaaaa
    54241 tccgtaacac ccttcgcttc ttgattgcta atacatctga tttcaaccct gctacggata
    54301 cagtagctta tgcagattta ggagctgttg ataagtacat gacaattgtc tttaatcagt
    54361 tggtagcaac gattactgac gcttatgagc gttatgactt tatggctatt tacaaagcag
    54421 tggtgaactt tgttacggtt gatttatcag ccttctatct tgattttgct aaagacgttg
    54481 tctatattga agctgccaat agcttagaac gtcgtcgcat gcagacagtc ttctatgata
    54541 tcttggttaa gattaccaag ttattgacgc caatcttgcc tcacactact gaagaaatct
    54601 ggtcttatct agagcatgag tcagaagcat ttgttcaatt ggcagaaatg cctgtggcag
    54661 aaactttctc agctcaagag gatattttag aagcttggtc tgctttcatg actttgcgta
    54721 cccaagctca aaaagctttg gaagaagcgc gaaatgctaa gattatcggt aaatcattgg
    54781 aagcccattt gaccatctac gctagcgaag aagtgaaaac cttattgact gctttagaca
    54841 gcgatattgc tttgcttttg atcgtgtctc aattaaccat tgctgacttg gcagatgcgc
    54901 ctgcggatgc agtggcattt gaaggtattg cctttatggt agaacatgcc ataggtgaag
    54961 tttgtgagcg ttcacgccgc atcgacccaa ctactcgcat gcgttcttac aatgcatttg
    55021 tctgtgatca cagcgctaaa atcattgaag aaaatttccc agaagctgtg gctgaagggt
    55081 ttgaagagag tggcaaataa gtcttatcaa gacttgaagt gacactgagt aagaagacaa
    55141 ccatcgggtc ttaggacctg atggtttttt agtagagctg attacgtcca ttagccagct
    55201 ttaatgagag acaaagtagg agaaatttag actacttttt ttatttcttt taagaaaatt
    55261 gctggcttca tataaggact attaagatag agttcacctt tcgctaataa aaaaacttag
    55321 ctcttttaga agggctaagt tttgtctgaa tagctagctg ctgtttatac agaagtttga
    55381 aatgaaattt caataaggtt attcgtgtga agtgtttttg attgtccagg aataacaatt
    55441 ttaggatcaa ttttacgttt taaaaaaaat tcgcgaatga tatcaagttc atcctccttg
    55501 atggcacggt atttatttga aataagtagt tcgtaatgtt ttggtgcttg ggtaaaaatg
    55561 acatctgtat ttcctgctga gtatacttcg actaaatagg catcggtgtt ttttagctga
    55621 tttctgatga gttctgggtg actgctagtg gtattgatga gtctcataaa tgtcctcctt
    55681 agtattcctg tacctattat agcactaatt taaagcctta gttagtagaa tgatgctttt
    55741 tttgccattc cttgactccc cattgatggc tctctcgttt taatttagca attgcctcga
    55801 taggagaaaa ccaacctaag ttattaaaat cttctaaggg cttagaaacg gcttgaaatg
    55861 cagttacttc ataaagatag gcaggatggt agaagtgggt atcacgatgg cgagagtaga
    55921 aatattcatc tgcctgaccg taatatgaac caatagtagc agaaaaacca agttcttcaa
    55981 tcagttcacg ctctagggcc tgaagctgac cttcacctgc ttcaatttca ccaccaggta
    56041 aaaaccagga accattagga gcttgaacaa gaataatttt tgtttgttcg tgattgggaa
    56101 tgatagcata gacaccgtaa cgtgtgacat agtctttatg tgcattttta tgtccaaatg
    56161 ttggaatcat cattttattt acctttcctt tttcttcatt atactaaatt tttgctaatt
    56221 attcttatca atttgtttag tttaataaaa aattgataga aaaagagaga gtctccttat
    56281 agaaactctc ttagctaacg ttaatcgaga gactcttcgt taagaaaaga atctccctct
    56341 ttaacagctt taatcgtgat gttttcactg tttgtcatca gtgcacgtaa ctgtttttca
    56401 gttgggtgtt ctaaataata gtctgtaatg gcatcttcga tataatcttg gatagtacga
    56461 cggagcggtc gagcgcccat tttaggatca tagcctaaat ctactaattt ttctttgacc
    56521 ttttgtgtca catcaagatg aatcccatta tagcctaagc gctcattaac atcttccagc
    56581 attaaatcaa cgatatgcag caaatgctct ttagataaag ctttgaattc aataatacca
    56641 tcgaaacgat tcataaactc tgggctgaag aagttgctta attcaccaag aacagaactt
    56701 gtccgtcctt ctctagcagc accaaatccg acagaagctt cgcttttacc tgttccggca
    56761 ttagaggtca tgataataat ggtgtccttg aagctgactg ttcgtccttg accatctgtt
    56821 aaacggccat catcaagaac ttgtaagaac atgtgcatga cgtcaggatg ggctttttcc
    56881 acctcatcta agagaataag tgaatatgga ttgcgacgaa cttgttcggt tagctgtcca
    56941 gcttcttcat agccgacata acctggagga gccccgacta atttggcgac agcgtgtttt
    57001 tccatgtatt cggacatgtc aaagcgaatc atattgtttg tcgaaccaaa gagttcaatg
    57061 gctagttgtt tagacaattc agttttacca accccagtcg gtccaacgaa taagaaagaa
    57121 ccaatagggc gatttggagt tcctaatccc acacggttac gacgaatagc cttagcgatt
    57181 ttatcaacag catcgtcttg cccgatcacg tgtgctttca gatcattggc taagtttacg
    57241 agttgagact gttccttttc ttttaagtcc ccaactggaa tattagtttt ttgctctaca
    57301 atagcttcaa tggttttttc agtaatgatg ggaatatctt gctcatcgac tttttgagcc
    57361 tgcatttctt tgtattttgt aatttgatcg cggaaataag ctgcgcgttc atagtcttcg
    57421 tctcgagtag cttgcgcctt gagattctca gcttcaataa gacgtttgtc aatttcttta
    57481 ggatcaacaa agttgagggt tagattcatt ttggaaccag cttcgtccag aagatcaata
    57541 gccttatcag gaagaaaacg gtcttgaata tagcggttag ataaatgagc ggcagcttca
    57601 atagcggctg ggctatattt gacatgatga tagtcttcgt atttcggttg gatacctttt
    57661 aaaatcgtga tggtttcctc aacagaaggt tcatcaactt taacgggttg catacgtcgc
    57721 tccaaggcag catctttttc aataatacgg tattcattta aggtagtagc accaacgagt
    57781 tgcaactcac cacgggccaa ggctggtttt aaaatattac cagcatccat attgccgtct
    57841 cctgcagaac cagcaccgac aatctcatga atttcatcaa taaagagaat cacatccttg
    57901 cgattgcgaa tttcttccat taatttttgc atgcgctctt caaactgacc acggatacct
    57961 gttccctgaa cgaggctaac cacatcaaga cgaatcactt gcttgccttg gagtttttga
    58021 ggaacagtac catcaataat tttttgagcc aaaccttcta caacagcagt tttaccaact
    58081 ccaggctcac caattagcac aggattattt ttagtacggc ggttgaggat ctcgataacg
    58141 cgtgtaatct cttcgtcacg accaataaca ggatcaatat taccatttct tgcaatatct
    58201 gtgacattaa tcccaaactc ttctaataag ccctttgctt gctgatttgg tgtttgtggc
    58261 tgagcaggtc gttgtccgtt gtagttacca ccatagcgtc ctccgccatt tccattttgc
    58321 cctgcctgag taggtggggt atttggaaga ttaccaaaag ctctaaaatt attcaaatca
    58381 ccaaaaaagt catcaaagaa aggacttgtg gatctatctt gtgctctata tcctggggtt
    58441 aggccattta aaatagaatt agtaggatcg gatttcatga tttgataaca attttgacag
    58501 agatcaacct gtctttgttt tccattaaca cttgtataaa gatgaatagt agattcgttt
    58561 aaattacaat tttgacacag cataatatac ctccgagggt ttatctaaaa gtcaaagtca
    58621 tttagtcaaa aatggtcaaa ctttatattc atattatagc accacggctt gggaaatcaa
    58681 gtaaaaagtt tatcgcttta gcgttagctt ttagagagta acatgacaga gtaactttat
    58741 taagtttcca atgagcaaat atttaaaatc attgaaaaga gtaaaaaaaa gtaaaatatc
    58801 aataaatata ttactttcct tgttagtttc ccttgttttg tgttaaaata agagggataa
    58861 aaaacgaata ggagaaacga aatggaatca catttggtga gaatcatcaa tcgtttggag
    58921 ttgatggtga cagatggcgg taatctcaag cgaaattttg aacgcgatgg tgttgttgtt
    58981 gcagaagttg ccttttcaaa tgatcctgaa aatggacctg ttttcacatt gcgtgatgtt
    59041 gaagcgcgtg agtcatattc ctttgatagc attgacttga ttgcaatgga aatctacgat
    59101 ttattatatt aagcttgaca tagtaaagag acttgcctga ggcaggtttt tttattgtca
    59161 aaaagtattg tattaatatt catcagatgg tataattatc tttattgtaa tgaacctagg
    59221 acttatgagg agatataaat ggatttgtca tttttgccca aatactgggc ctactttaac
    59281 tacggtgtac ttgtcaccat tatgatttca atcagcgttg tcttttttgg aacccttatt
    59341 ggtgtcttgg taaccctgat taagcgtagt catgtgaagc cgttgacctg ggtcgttaat
    59401 ctttacgttt ggatctttcg gggaacacct atggtggttc aaatcatgat tgcctttgct
    59461 tggatgcatt ttaacaatat gcctactatt ggttttgggg ttttagactt ggacttttca
    59521 agactacttc ctggaattat tatcatttca ttgaatagcg gtgcttatat ttcagaaatt
    59581 gttagagcag gtattgaggc tgtaccaaaa gggcaattag aagcagctta ttcactaggt
    59641 attcgtcctc aaaatgccat gcgttatgtg attttgcctc aggcctttaa aaatattttg
    59701 ccagccttag gaaatgaatt tattactatt attaaggata gtgctctttt acaaaccatt
    59761 ggagtgatgg agctttggaa tggtgcccaa tcagtggtaa cggctactta ttctccaatt
    59821 tcccctttac tggtggctgc tttttactac ttaatgatca caacagtgat ggcacagtta
    59881 ttggcagtct tagaacgtca catggcgcaa ggaggtaatc attgatgact gaggctatta
    59941 tttcaattaa agatttgcac aagtattatg ggcacaatga agtgcttaag ggaattgatt
    60001 tagacattat gccaggagag gttgtggtga ttattggccc ttctggttct ggaaaatcga
    60061 ccttacttcg aactatgaat cttttggaag taccaactaa gggacagatt aggtttgagg
    60121 ggattgatat taccgataag aagaatgata ttttcagcat gcgtgaaaaa atgggaatgg
    60181 ttttccagca gtttaacctc tttcccaata tgactatttt agaaaatatc actttatcgc
    60241 caatcaaaac taagggaatg gctaaagcag aggctgacaa aacagccttg agcttgttgg
    60301 acaaagttgg attatcagaa aaagccaagg cttatcctgc tagtctttct ggtgggcaac
    60361 agcagcggat tgcgattgcg cgtggactgg ctatggatcc agatgtttta ctctttgatg
    60421 aaccaacttc agctctagac ccagaaatgg tgggtgaggt cttggctgtc atgcaagatt
    60481 tggctaaatc tgggatgact atggttattg tgactcatga aatgggcttt gctaaagaag
    60541 tcgcagatcg tgtgattttt atggatggcg gcgttattgt ggaagaagga agtcctaacc
    60601 aactttttga tctgactaaa gaagaacgta caaaagattt tttgagtaga gtattataaa
    60661 tctgttctat gaattataaa aggaagtcct aaatcattta ggacttcctt ttataatttg
    60721 ctaaggcatt ttataggaga ttacttttct ttttgttaaa ataaaaagaa atagttgcat
    60781 tatttgcata gaagaaaggg atctgttatg gtttcagtga tgtggtttcg tagagattta
    60841 aggattgatg atcaaaaagc tttagctcat gctattgcta gtcaatcacc aaccttatgt
    60901 gtgtttcaat ttaacaagga gcaattaaat ctgctacata gtcggaatca atctagtttt
    60961 attactagcg ttttggcttt tagaaagtta ttaaaatgtg aaggtattga cttatatcta
    61021 atgtatggag acttaatgac ctgttttgag caattattga cacaattaaa agactggaca
    61081 gatgtgtatt ttaactatga tgaatctgga tatggtcgtt tacgtgatca aaaagcagca
    61141 caatttttca aaaaaaatgg gattgctgtt catacctacc aaaatcacta tttacatggt
    61201 agtcaagaga tcattaacca atcaggtcag ccttataaag tttttacgcc ctactatagg
    61261 atttggcaaa attatccgaa agagactcct attaaagtag aactatcgca aggcaggtgg
    61321 ttaaatcttg agacaccaga tgatgtttta aggactgttg agagttttaa agatgaaaaa
    61381 tatcaggatg ttgcaacttt tgatgaagcg tcaaaacaac taaatcgatt tattcaagac
    61441 caattagcag cttatcacgc taatcgagat tttccagcgc agctagggac gagtcggttg
    61501 tctccttttt taagaatagg agctattggc attcgcacgg tatatcacgc tgtgcgtcaa
    61561 gcaccaaata gtctagggca agctactttt ttaaaagaat tagcttggag agacttttac
    61621 aatatggtct atgtggctta tcctgatcag aaaactcagc ctatccaaaa agccttttct
    61681 caaatcgaat gggttaataa tcctgactgg tttcagttgt ggaaagaagg taaaacgggt
    61741 taccctattg ttgatgctgc catgcttcag ttacaaaaga caggatggat gcataatcgt
    61801 ttacgaatga tagtagcttc ttttttaact aaagatcttt tatgtgattg gcgtttagga
    61861 gagcagtatt ttcaacaaca actaattgat tatgatgctg ccagtaatat cggaggatgg
    61921 cagtgggctg cttccactgg aacagatgct gttccttatt ttagaatatt taatcctgtt
    61981 actcaaggta agcgttttga tcccaaaggc gagtttatta aagcgtattt gcctcaacta
    62041 gaacacgttc cagagaagta tctccacgaa ccgtggaaga tgccaaaata ccttcaagag
    62101 agtgtatcct gtattattgg cacagactat cctcaaccaa ttgtcgatca tgctaaacaa
    62161 cgtgaacaag ctattgcaaa gtatgagtgg gcaaaagaaa aagcaaaaat agaatgactg
    62221 ttctcattat aagagtttaa acaaaaagtt atcatgaatt aagattattt aatttaaaaa
    62281 ataagttgac tttatttaga ttatttgata ctattcagtt gtctccctta gagaaagcga
    62341 tttcttgttt tggagctgat ttttaccatt tggtcttaga ataggatgag taatatgact
    62401 tacaacgagg tatatcaaga atggttgcac aataatgatc ttagtgatga tattaaagca
    62461 gatttagcag ccataaaaga caatgaggct gagattcaag atcgttttta caaaacactt
    62521 gaatttggaa cagcagggct aagaggaaaa cttggagcag gcaccaatcg catgaatacc
    62581 tatatggttg gtaaggcagc acaagcttta gctaatacta ttattgatca tggacctgaa
    62641 gcggttaaaa agggcattgc ggttagttat gatgttcgct atcaatctag aacatttgca
    62701 gaattaacat gctctattat ggcagctaac ggtattaagg cgtaccttta taaagggatt
    62761 cggccaacac caatgtgttc gtacgctatt cgtgctttgg gatgtatctc tggtgttatg
    62821 attacagcta gtcacaatcc ccaagcttac aatggttata aagcttattg gcaagaaggt
    62881 tctcaaattt tggatgacat tgcggatcaa attgcacaac acatggctgc actaactcag
    62941 tatgaggaaa tcaaacaaat gccttttgaa aaggctctgg acagtggact tgttacttat
    63001 attgatgaga gtattgaaga agcatataaa aaagaagtgc ttggtttaac gattaatgat
    63061 actgacattg ataagtcagt ccgagtagtc tatacccctt taaatggtgt tgggaatcta
    63121 ccagtgcgtg aggttttaag acgccgcggt tttgaaaatg tttatgtggt acctgagcag
    63181 gaaatgcccg atcctgattt tacaacagtt ggctatccta atcccgaagt ccctaaaact
    63241 tttgcatatt cagaaaaatt aggtaaggca gttgatgctg atattttgat tgcaactgat
    63301 ccagattgtg accgtgtggc tttagaagtt aaaaatgcag tcggtgacta tgtttttctc
    63361 aatggcaata aaatcggagc gcttttatct tactatatct tttcgcaacg atttgactta
    63421 ggcaatttac cggctaatcc tgttttagtg aaatccattg taacaggaga cttgtcacgg
    63481 gctattgcta gccattatgg tattgaaacc gttgaaacat tgactggttt taagaatatt
    63541 tgtggcaagg caaacgaata tgatgtgacg aaacagaaaa actacctgtt tggttatgaa
    63601 gaaagtattg gtttttgcta tggcactttt gttcgtgaca aagacgctgt tagcgcctct
    63661 atgatgattg tagaaatggc agcttactac aagaaaaagg ggcagaattt actagatgtt
    63721 ttgcagacta tttatgcgac atttgggtat tataatgaac gtcaaattgc cttggagctt
    63781 gaggggatag aaggacaaaa acgcattgcg aggataatgg aagatttcag acagacacca
    63841 atagctagtg ttgcagagat ggcgttagac aagacaattg attttattga tggctatcaa
    63901 gattttccaa agcaaaactg tctcaaattt tatttggatg atggttcttg gtatgcactt
    63961 agaccatcag gaacagagcc taaaataaaa ttttatttat atactattgg ccaaacacaa
    64021 gaaaatagtg caacaaaatt agatgctatt gaagcagcgt gtcgcacaaa aataaatcag
    64081 gttaattaaa catcaaaaat ggataacact tttacactat tttccatata aacaactaca
    64141 aaaggaggtg agacttttag gcaccttctt tttcttgtag gtgccactaa tcaatttaat
    64201 cgactcaaat caatactaaa aaataagtaa gagtataaag aacaggcatc tatttttttg
    64261 ttataataga aaaatgaaat taaagggaga tgtcaatgac agaactaatt gatggtaaag
    64321 ccttagctca aaagatgcaa caagagttag cagctaaagt caacaatcta aaacaaaaaa
    64381 aaggaattgt accaggctta gccgttattc ttgtaggtga tgatcctgct agtcaggtgt
    64441 atgtccgtaa taaagagcgt gcagctctta ctgtaggttt taaaagtgag accgttagat
    64501 tatcagaatt catttgtcaa gaagagctta ttgcagtaat cgaacgttac aatgcagata
    64561 acactattca tggtatttta gtgcagctac ccctgccaaa tcatattaat gataaaaaaa
    64621 ttattctcgc cattgatccc aaaaaagatg tggatggttt tcacccgatg aatacaggtc
    64681 acctttggtc aggacgtccc ttaatggttc cttgtactcc atcagggatt atggaattgc
    64741 ttcgagaata taatgttaac cttgaaggta aacatgccgt cattattggc agatcgaata
    64801 tcgttggaaa accaatggca cagctcttac tagacaaaaa tgcaacagtc acgttgacac
    64861 attcaagaac acgtcaatta gaagaagtat gtcgctgtgc agatgtgttg attgtggcaa
    64921 tcggacaagg tcatttcata acaaaacaat atataaaaga tggtgcgata gtgattgatg
    64981 tgggaatgaa ccgtgatgat aatggcaagc taattggaga tgtggccttt gatgaggtgg
    65041 cagaagttgc agcgaaaatc acccctgtac caggaggtgt cggtcctatg acgattgcta
    65101 tgttgctaga gcaaacttat caatctgctc tccgtagtac tcataaatag ttatcattag
    65161 acaattcaac ataagagaat ataagaagtc agcaatggct tccttttttg tttttctgct
    65221 cactatttat ccagaaaaat ggtataattg cattagtatg caaagggact atgtcaggtc
    65281 caactaagtg aaaggtggct tgatggcaga ttatttaacc gtcactcatt tgacgaaata
    65341 tttaaaatta aaatttgacc gtgaccctta tttggaacgg gtttatctga ctggtcaagt
    65401 gtccaatttt cgaaaacgac caactcatca atatttttcc ttaaaagatg aaagtgctgt
    65461 gattcaagcc accatgtggg caggagtcta taaaaaacta ggatttgacc tagaagaagg
    65521 catgaaaatt aatgtgattg ggcgagtcca actttatgaa ccgagtggtt cctattctat
    65581 cgtgattgaa aaggcagagc cagacggcat aggtgccttg gctttgcagt ttgaacaatt
    65641 aaagaaaaaa ttaactgcag aaggttattt tgagcaaaaa cacaagcagc tcttaccaca
    65701 gtttgtgtca aaaattgggg tcattacaag tccaagtggc gctgtgattc gagatattat
    65761 cacaactgtt tcacggcgtt ttccaggggt tgagatttta ttattcccaa ctaaagtaca
    65821 aggtgatgga gccgcccaag aagtagtggc gaatattcga agagccaacc aaagagagga
    65881 tttggacttg ctcattgttg gccgtggagg tggctcgata gaagaccttt gggctttcaa
    65941 cgaggaaata gtagttcagg ctatctttga atcgcaactt ccagtgattt cgagtgtggg
    66001 tcatgaaact gatacaaccc tggcagattt tgtggcagat cgcagagcag ccacaccaac
    66061 agcagcagca gagttagcaa cgcctattac aaaaacagat cttatgtctt ggatagtaga
    66121 gcggcaaaat cgttcttatc aggcctgctt gaggcggatt aagcaacggc aagagtgggt
    66181 ggataaacta tcacaatctg ttatttttag gcaaccagaa cgattatatg atgcctactt
    66241 gcaaaaaatt gatcgcctta gcatgaccct gatgaatacg atgaaagatc gtctgagctc
    66301 cgccaaagaa aacaaggttc agttggacca tgccttggcc aatagtcaat tacagacaaa
    66361 aatcgagcga taccaagacc gtgttgctac cgctaagcgt ttactgatgg ctaatatggc
    66421 tagtcaatat gatagtcagc tggctcgctt tgaaaaagca caggatgctt tgctatcact
    66481 ggatgccagc cgaattatcg cccgtggtta tgcaatgatt gaaaaaaatc aagcactggt
    66541 agcctctgta agtcagataa caaagggtga tcagttaacc attaagatgc gtgatggaca
    66601 attagatgta gaggtaaaag atgtcaaaaa cgaaaacatt tgaagaaaat ttacaagatt
    66661 tagagactat tgtgaacaaa cttgaaaatg gggatgtccc tttggaagaa gctatttcag
    66721 aatttcaaaa aggaatgctt ctctcaaaag aacttcaaaa gaccttacaa gcggcagaaa
    66781 aaacactcgt caaagtgatg caagctgatg gcacagaagt agatatggat gattaatgga
    66841 caaattagct agaattgacg aagccattcg tcgctactat aagacgacta gtaacggtgt
    66901 atctgaagag ttgattgatg ctatcttgta ttctgttgac agtggtggca agcgcattcg
    66961 accacttatc ttattagaga tgattgaggg atttggggta tcgttacaga atgctcattt
    67021 tgatttggct gcagcccttg aaatgattca tacaggaagt ctgattcacg atgatttgcc
    67081 agccatggat aatgatgatt accgacgtgg tagactgacc aatcacaaac aatttggaga
    67141 agctacggcc attttggcgg gagatagctt atttttagac ccctttgggt taatagctca
    67201 agctgaatta aatagcgagg ttaaagtagc cttaatccaa gaactttccc tagcttcagg
    67261 aacttttggc atggttggtg gtcagatgct agatatgaaa ggggaaaatc aagctttgag
    67321 tctccctcag ttgtcactga ttcacctcaa taaaaccgga aaattattaa cttttccttt
    67381 taaagcagca gctcttgtaa cagaacaggc tattactgtt cgtcaacaac tagagcaggc
    67441 gggaatgctc atcgggcacg cctttcagat tagggatgat attttagacg tgacagctag
    67501 ctttgaagat cttggaaaaa cgcctaaaaa ggatttattt gcagaaaaag ctacttaccc
    67561 aagtttactg gggttagaag cctcctacca actgttgaca gagagtttag atcaggcttt
    67621 gacgattttt cagacactcg aaagcgatgt aggctttaag cctcaaataa ttacaaaact
    67681 gatagaaggg ttacgactta atgcctaaag aaagagtaga tgtgttagcc tataagcaag
    67741 gattatttga gaccagagag caagctaagc gtggtgttat ggcaggctta gtggtctctg
    67801 tgattaatgg ccaacgctat gacaagccag gtgacaaaat tgacgatggg actgagttaa
    67861 aacttaaagg tgaaaaattc aaatacgtca gtcgtggtgg attaaaactg gaaaaggggc
    67921 tgcacgtttt tggtgtatcg gttgctaatc aaattgggat tgatattggc gcttcaacag
    67981 gtggttttac cgatgttatg ttacaagatg gggccaaact agtctatgcc gtcgacgttg
    68041 ggactaacca gttggtatgg aaactcagac aagatccacg agtaagaagt atggaacagt
    68101 ataactttcg ttatgctcag ccagaggact ttaatgaggg acagcctgta tttgccagta
    68161 ttgatgtgtc ctttatttct ctcagcttga ttttgccagc cctgcataac gttttgtcag
    68221 atcagggaca ggttattgct ctcattaaac cgcaatttga agctgggcgc gagcagattg
    68281 gtaaaaaagg catcgtcaaa gacaaacaga ttcatgaaaa agtgattcaa aaggtcatgg
    68341 attttgcctc aggttacgga tttacagtta agggacttga tttttcccct attcagggtg
    68401 gtcatggcaa tatcgaattt ttagctcatc ttgctaagtc acagacacct gaaacgttag
    68461 ccccgcattt gattcagaaa gttgttgcca aggcacataa ggagtttgag aaacatgaaa
    68521 aagagtgaac gacttgaatt aatcaaaaaa atggttttga cgcatccaat tgagacgcaa
    68581 catgatctct taagattatt ggcagagcat gggttagaat taacccaggc tactatttca
    68641 agagacatga atgaaattgg tatagtaaag attccttctg gcagtggacg ttacatctat
    68701 ggtctttctc aagatagtgg aaaaaagatc gttcaaggac ctagatcgat aaagagcact
    68761 attttagctg tatctgacaa aacaaaaggt ttagaacaac acctctattt aaaagtcgta
    68821 cctggcaata gtaaattaat caaacgttat ttattagcag atttttcaaa agctattttt
    68881 agtcttattg ctgatgatga tagtttactg ttaattgcaa agtctccttc agaagcagat
    68941 atgatacgcc aagaaatttt gctttggatg cagggtataa cctagaaaaa aataggggag
    69001 aaagtgatgt tattagaaat ttctattaaa aattttgcta ttattgatga aatttcccta
    69061 aattttgaaa atggtatgac ggttttgacg ggtgaaactg gagcaggaaa gtctattatc
    69121 attgatgcta tgaatatgat gcttggtgcg cgtgctagta cagaagtgat tcgtcgtgga
    69181 gctaataaag cagaaattga ggggttcttt tcggtagatg ctaccccaga actggttgcg
    69241 tgtctggaat catcaggtat tgctatggaa gaagaactga ttattcgccg agatatcttt
    69301 gccaatggca gaagcgtgag ccgcattaat ggtcagatgg ttaacctagc caccttaaaa
    69361 caggtcggac agtttttggt agatattcat gggcaacatg accaagaaga attaatgcga
    69421 ccacagctcc accagcaaat tttggacgct tttggtgata aggcttttga gcaattgaaa
    69481 gagaactatc agcttatttt tgatcgttat aaaagcttgc gtcgccaggt tattgacaaa
    69541 caaaaaaatg aaaaggaaca caaagatcgt attgatatgt tggcctttca gatagcagaa
    69601 attgaagctg ctgccttgag tcgaggtgag gacgaccggt taaatcaaga acgtgatcgc
    69661 ttaatgaacc acaaacaaat tgctgatacc ctgaccaatg cctacgtcat gctagataat
    69721 gacgattttt caagtctatc caatattcgc tctagcatga atgacttact atcaattgag
    69781 cagtttgatt cagaatacaa agggatgtcg acttcgattt ctgaagccta ttatattctt
    69841 gaagaagtga gcaagcaatt atcagatacc attgaccaac tggattttga tggtgggcga
    69901 ttacaggaaa ttgaatttcg cttggataca ctcaatagct taacccgtaa atacggtggt
    69961 aatgtgaatg atgtgcttga ctactacgat aatatcgtca aagaatacca gctattaaca
    70021 ggcgatgagt tgtcttcagg ggatctagag gcagaattga aagccttaga aaaacaattg
    70081 gttgctgctg cttcggagtt aagtgtctct cgccatcaat tggcggagca attagaagct
    70141 gagattaaag ctgaacttaa ggaactttat atggaaaaag cagatttcaa agttcacttt
    70201 accacatcaa aattcaatcg tgatggtaat gaaagcttgg aattttacat ctccaccaat
    70261 ccaggtgaag gattcaagcc ccttgtcaag gtggcttcgg gcggcgaatt atcacgcttg
    70321 atgttggcca tcaaggcagc tatctctaaa aaagaagata aaacgagtat tgtttttgat
    70381 gaagtagata caggtgtttc tggtcgagtt gctcaagcca ttgcccaaaa gatttataaa
    70441 attgggcgac atgggcaagt tctcgctatt tcacacttac ctcaagtcat tgccatcgct
    70501 gattaccagt attttatttc taaagagagt aaagaagagt ccactgtttc gaaggtaagg
    70561 ttgttaactt ctgaagaacg tgtggaagaa attgccagaa tgcttgctgg tgcagacatg
    70621 acagaagctg ctctcactca ggctcgtgaa ttactggcca aacattaata aacagaaaaa
    70681 actgtgacta ttcaatagaa tagtcttttg ataagaaaga gaaaccgtcg gattagcctg
    70741 ttgttagatt ctggagcctt agcgctccga tgccatctag caggacgttt ggcggtttct
    70801 ttttgctcaa ctgtcttgac aaacccctga taaatagtag aatatataag agaattttaa
    70861 gctgagggga tagaaatgac tagtaaaaaa gcgtgtttat caagtatcat tgtgttagca
    70921 agtttaacgt gtggaaatga tactgttagt gccaatcatc tctcagcaac tggagataag
    70981 tttgatgatt gctcaacact tgttgaaaaa gatgtggccc ctaaagatga acttgagatg
    71041 ttagcatggt cctcgtctca aacaactgat gatgctgaca gagactatga agattttctc
    71101 gatgatgatt cttttaatga tgattctttt atttctcaaa atgaaactga taagatgttt
    71161 gagaatttaa ctgatgatag gttattaaat gaattagatg aattagatga attagatgaa
    71221 gaagatacaa ttgagccaga gcaaaatgta ataatgccta gtgacgatga gctatttgat
    71281 ttaactgatg ctgttgagac acgccttact gtttctagtg ctccccattt agaggctgaa
    71341 ttgccgaaac cacatttgag gagcctatca gatacagcac tgcggtctgg tgaaattaga
    71401 ggacatttag ataacaaact ggacactttg tctgtaacag ctacaaagtt agcattaacg
    71461 atggctcaaa aatttgattt gacaacgcat gtctattcta taggtgaaag ctttagtgaa
    71521 gtattagctg ctcattatga agacagaaaa gcagaatcag ctttttctaa gaaaaagaga
    71581 tttcaccttc ctattgctac tccagatgtt gttatagagg agttaaggcg cctagtctct
    71641 tctattggaa gttcaaaaga agatgtttca gttccttata atcggaagct aggtatggca
    71701 gttgcaaaaa gaaaaatagc cctgccacaa acgggagagg agttctctta ttatccagct
    71761 ttacttggtt taatgatatt aggattaacg ccgattatga taccaaagaa gataaataat
    71821 taggtaataa gttattgtag ttgtaaaaga cggggcaaat gttcaagcgt gaaaaggttg
    71881 acttttgcct cgttttgtat ctcgttattg ctaaggcatt ttcttcgagc agctagtgct
    71941 cgccatacct atctaccgag tgattattca atagcactac cagttttgct ttatttagta
    72001 aggagtgtta gaataaagag gtgagaaact agtttagaat ggaaaaatac atgggaacta
    72061 taaaaattgt tacagattca tcaataacta ttgaaccaga attaattaaa gctttagata
    72121 ttactgtagt gcctttatct gtcatgattg atagcaaatt atattctgat aatgatttaa
    72181 aagaagaagg tcattttttg agccttatga aggctagcaa atcccttccc aaaaccagtc
    72241 agccaccggt tggtctcttt gctgaaactt acgaaaattt ggtcaaaaaa ggagtaactg
    72301 acattgttgc tattcacctc tcaccagctt tatcaggtac tattgaagct tcccgtcagg
    72361 gggctgaaat cgctgaggca cctgttacag ttttagattc aggatttact gatcaagcca
    72421 tgaaatttca ggtcgttgag gcagcaaaga tggcaaaagc gggtgctagt ttgaatgaga
    72481 ttttggctgc tgttcaagct atcaaatcaa aaacagagct ctacattggt gtatctacct
    72541 tagaaaattt agtaaaagga ggtcgtattg gtcgtgtgac gggtgttttg agctcgctac
    72601 ttaatgtcaa agttgttatg gcacttaaaa atgatgagtt aaaaacgctt gtcaaaggtc
    72661 gaggtaataa aacatttacg aaatggttag atagttacct cgctaaaaat agtcatcgcc
    72721 cgattgcaga gatagctatt tcttatgctg gtgaagctag cctggcatta accttaaaag
    72781 aaagaatcgc agcttattac aaccactcta tttcggtttt agaaacaggc tctatcatcc
    72841 aaacacatac aggagaagga gcttttgcgg ttatggttcg ttatgaataa tcgtcattta
    72901 tttagtggga tatttttctt tgttattagt ttatgtctgg cctttttatt gctaaatatt
    72961 attatcccta agtcaaattc acgtttgaaa aagagtgatt ttctgaaaaa agaacaagta
    73021 gctatccaat atgttgctat aggagattca ttgacagaag gagtaggtga tctaactcat
    73081 caaggtggtt ttgttccttt gttaacgaat gatctcagtg aatattttaa ggctaatgtt
    73141 aatcatcaaa attacggcgt atctggtgat accagtcaac aaattcttga taggatgata
    73201 aaacaaaagc agatacagtt atctttaaaa aaagcagata taatgacgtt aaccgttggt
    73261 ggtaatgatg ttatggcagt tattcggaag aatttagcgg atttgcaagt ttctagtttt
    73321 agaaagccag ctcgtcagta tcaaaaacga ttaagacaga ttatcgagtt agccagaaaa
    73381 gataataaag atcttcctat ttttatttta ggcatctata atccgtttta tttgaatttt
    73441 ccagaactaa ctgatatgca aaaagtgatt gatgactgga ataccaaaac taaggaggtt
    73501 gttggagaat acgatcgtgt gtactttgtg ccaataaatg acctcttgta taaagggata
    73561 aatggacaag aaggaattgt ccattcttca ggagatcaaa ctacaattgt caatgatgcc
    73621 ttgtttactg gggaccattt tcacccaaat aatactggct atcaaatcat gtcaaatgca
    73681 gtaatggaga aaataaaaaa gcatgaaaaa aaaatcaaac cttaattggt ggaagtggag
    73741 cttcttatgt ctgcttgctt ttaatactgc ctttttgatg gttattgcaa gtcgtctcat
    73801 tcaagtaaga gaacctgagt cagaactgat tgctaaaaaa ccagttaaaa atatcaaaat
    73861 tggtacattt gtcacaacca gagaacagct taacgaaact gtagcaagtt atcttaaaga
    73921 ttatcagact aaaaaaatgt cttataaatt ttatgcgaca tcttcttcta ttttgtttga
    73981 aggaacttat caattattag ggtatgaagt ccctttatat atctattttc aacctcatcg
    74041 tctagaaaat ggagctgtcc aactacaggt gatctctttt tcagtgggaa ctctgccact
    74101 cccagaaaaa gatgttttgc agtatttgaa atcaagctac aaattgccaa gctttgttaa
    74161 agtgatgcca aatcaatcag ctatcgttgt taatttacaa gatatccaaa atgatgctaa
    74221 ggtttattta aaagccaaga aa
//
LOCUS       DAUGOH010000006        61557 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUGOH010000006 DAUGOH010000000
VERSION     DAUGOH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61557
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.006"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            60..1256
                     /locus_tag="VH957_000392"
     CDS             60..1256
                     /locus_tag="VH957_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEQ8558334.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            1519..2070
                     /locus_tag="VH957_000393"
     CDS             1519..2070
                     /locus_tag="VH957_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8558335.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            2137..2508
                     /locus_tag="VH957_000394"
     CDS             2137..2508
                     /locus_tag="VH957_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8558336.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            2546..3892
                     /gene="glnA"
                     /locus_tag="VH957_000395"
     CDS             2546..3892
                     /gene="glnA"
                     /locus_tag="VH957_000395"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEQ8558337.1"
                     /translation="MAITVADIRHEVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPIEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFISQWEIDHYIHNY"
     gene            complement(4120..5802)
                     /locus_tag="VH957_000396"
     CDS             complement(4120..5802)
                     /locus_tag="VH957_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8558338.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(5804..6034)
                     /locus_tag="VH957_000397"
     CDS             complement(5804..6034)
                     /locus_tag="VH957_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEQ8558339.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            6317..7015
                     /gene="tsaB"
                     /locus_tag="VH957_000398"
     CDS             6317..7015
                     /gene="tsaB"
                     /locus_tag="VH957_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEQ8558340.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHAPLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            6987..7442
                     /gene="rimI"
                     /locus_tag="VH957_000399"
     CDS             6987..7442
                     /gene="rimI"
                     /locus_tag="VH957_000399"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEQ8558341.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIW
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLGSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKNDR"
     gene            7432..8460
                     /gene="tsaD"
                     /locus_tag="VH957_000400"
     CDS             7432..8460
                     /gene="tsaD"
                     /locus_tag="VH957_000400"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEQ8558342.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(8631..8900)
                     /gene="rpsN"
                     /locus_tag="VH957_000401"
     CDS             complement(8631..8900)
                     /gene="rpsN"
                     /locus_tag="VH957_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEQ8558343.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(9121..9879)
                     /locus_tag="VH957_000402"
     CDS             complement(9121..9879)
                     /locus_tag="VH957_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8558344.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSCQSDTH"
     gene            10120..10899
                     /gene="udp"
                     /locus_tag="VH957_000403"
     CDS             10120..10899
                     /gene="udp"
                     /locus_tag="VH957_000403"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEQ8558345.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            10920..12122
                     /locus_tag="VH957_000404"
     CDS             10920..12122
                     /locus_tag="VH957_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEQ8558346.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            12152..12823
                     /gene="deoC"
                     /locus_tag="VH957_000405"
     CDS             12152..12823
                     /gene="deoC"
                     /locus_tag="VH957_000405"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEQ8558347.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECEDAIKNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAETFIALGASRLGTSRIIKIVKNEAT
                     KPDSY"
     gene            complement(12918..14087)
                     /locus_tag="VH957_000406"
     CDS             complement(12918..14087)
                     /locus_tag="VH957_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8558348.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVRLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGKVLTSTEVVSVKKQDDLFYLKSADQTFSCHKLVV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            14292..14822
                     /locus_tag="VH957_000407"
     CDS             14292..14822
                     /locus_tag="VH957_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEQ8558349.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            14871..15458
                     /locus_tag="VH957_000408"
     CDS             14871..15458
                     /locus_tag="VH957_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEQ8558350.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHIIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            15610..16347
                     /locus_tag="VH957_000409"
     CDS             15610..16347
                     /locus_tag="VH957_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8558351.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
                     SNYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPR
                     TRKLTCSHCHQKSYCLELAKEDTVSRG"
     gene            complement(16404..16703)
                     /locus_tag="VH957_000410"
     CDS             complement(16404..16703)
                     /locus_tag="VH957_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEQ8558352.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(16896..17270)
                     /locus_tag="VH957_000411"
     CDS             complement(16896..17270)
                     /locus_tag="VH957_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8558353.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            17440..17661
                     /locus_tag="VH957_000412"
     CDS             17440..17661
                     /locus_tag="VH957_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8558354.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(17741..20023)
                     /locus_tag="VH957_000413"
     CDS             complement(17741..20023)
                     /locus_tag="VH957_000413"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEQ8558355.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKANIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIVNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFETSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALVDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGNTLRVILYTTDFEHTVRDNS
                     NYTLTIDLSQSQLIVPIASN"
     gene            complement(20045..20704)
                     /locus_tag="VH957_000414"
     CDS             complement(20045..20704)
                     /locus_tag="VH957_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8558356.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            20870..22066
                     /locus_tag="VH957_000415"
     CDS             20870..22066
                     /locus_tag="VH957_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8558357.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTFLYLLKTK
                     TRQVVS"
     gene            22538..23386
                     /locus_tag="VH957_000416"
     CDS             22538..23386
                     /locus_tag="VH957_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8558358.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKVSYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(23722..24618)
                     /locus_tag="VH957_000417"
     CDS             complement(23722..24618)
                     /locus_tag="VH957_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEQ8558359.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            24916..25668
                     /locus_tag="VH957_000418"
     CDS             24916..25668
                     /locus_tag="VH957_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEQ8558360.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            25653..26603
                     /locus_tag="VH957_000419"
     CDS             25653..26603
                     /locus_tag="VH957_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEQ8558361.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADTTVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKVLNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(26783..29110)
                     /gene="pflB"
                     /locus_tag="VH957_000420"
     CDS             complement(26783..29110)
                     /gene="pflB"
                     /locus_tag="VH957_000420"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEQ8558362.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            29319..30413
                     /gene="dinB"
                     /locus_tag="VH957_000421"
     CDS             29319..30413
                     /gene="dinB"
                     /locus_tag="VH957_000421"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEQ8558363.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDLVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKVRGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(30506..30988)
                     /locus_tag="VH957_000422"
     CDS             complement(30506..30988)
                     /locus_tag="VH957_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558364.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTLSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(31079..33532)
                     /locus_tag="VH957_000423"
     CDS             complement(31079..33532)
                     /locus_tag="VH957_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEQ8558365.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKIADALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTYFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQAVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(33590..34183)
                     /gene="lepB"
                     /locus_tag="VH957_000424"
     CDS             complement(33590..34183)
                     /gene="lepB"
                     /locus_tag="VH957_000424"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8558366.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(34194..35096)
                     /locus_tag="VH957_000425"
     CDS             complement(34194..35096)
                     /locus_tag="VH957_000425"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEQ8558367.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHPFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            35253..35561
                     /locus_tag="VH957_000426"
     CDS             35253..35561
                     /locus_tag="VH957_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558368.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            35564..36109
                     /locus_tag="VH957_000427"
     CDS             35564..36109
                     /locus_tag="VH957_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEQ8558369.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            36258..38597
                     /locus_tag="VH957_000428"
     CDS             36258..38597
                     /locus_tag="VH957_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEQ8558370.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELSELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNISFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPILADKGSKIAVFNNIFADIGDEQSIEQNLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG"
     gene            38601..39101
                     /locus_tag="VH957_000429"
     CDS             38601..39101
                     /locus_tag="VH957_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8558371.1"
                     /translation="MESYEHFYAKLSQPFRKTPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            39182..39496
                     /gene="trxA"
                     /locus_tag="VH957_000430"
     CDS             39182..39496
                     /gene="trxA"
                     /locus_tag="VH957_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEQ8558372.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQTPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(39548..40135)
                     /locus_tag="VH957_000431"
     CDS             complement(39548..40135)
                     /locus_tag="VH957_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8558373.1"
                     /translation="MEIGQQIIRYRKQQALSQEELAEKVYVSHQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSSGKLLDEIEKREE
                     RAKLPYQNPLIVTVFFLITVAIFFASRFMFTWLFH"
     gene            complement(40312..41436)
                     /gene="mutY"
                     /locus_tag="VH957_000432"
     CDS             complement(40312..41436)
                     /gene="mutY"
                     /locus_tag="VH957_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEQ8558374.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKHFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQSGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            41634..41927
                     /locus_tag="VH957_000433"
     CDS             41634..41927
                     /locus_tag="VH957_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558375.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            42100..42390
                     /locus_tag="VH957_000434"
     CDS             42100..42390
                     /locus_tag="VH957_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEQ8558376.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGANVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            42412..42903
                     /locus_tag="VH957_000435"
     CDS             42412..42903
                     /locus_tag="VH957_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8558377.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            43068..43307
                     /locus_tag="VH957_000436"
     CDS             43068..43307
                     /locus_tag="VH957_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEQ8558378.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(43440..44096)
                     /locus_tag="VH957_000437"
     CDS             complement(43440..44096)
                     /locus_tag="VH957_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEQ8558379.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(44228..45172)
                     /locus_tag="VH957_000438"
     CDS             complement(44228..45172)
                     /locus_tag="VH957_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEQ8558380.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            45375..48203
                     /gene="uvrA"
                     /locus_tag="VH957_000439"
     CDS             45375..48203
                     /gene="uvrA"
                     /locus_tag="VH957_000439"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEQ8558381.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
                     GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            48318..49391
                     /locus_tag="VH957_000440"
     CDS             48318..49391
                     /locus_tag="VH957_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8558382.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLNVVAELLGADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDVSEIETIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIAASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFLGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            49426..49887
                     /locus_tag="VH957_000441"
     CDS             49426..49887
                     /locus_tag="VH957_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEQ8558383.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            49983..50540
                     /gene="efp"
                     /locus_tag="VH957_000442"
     CDS             49983..50540
                     /gene="efp"
                     /locus_tag="VH957_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEQ8558384.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            50586..50975
                     /locus_tag="VH957_000443"
     CDS             50586..50975
                     /locus_tag="VH957_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8558385.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            50968..51420
                     /gene="nusB"
                     /locus_tag="VH957_000444"
     CDS             50968..51420
                     /gene="nusB"
                     /locus_tag="VH957_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEQ8558386.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(51561..52526)
                     /locus_tag="VH957_000445"
     CDS             complement(51561..52526)
                     /locus_tag="VH957_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8558387.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEILKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(52531..53970)
                     /locus_tag="VH957_000446"
     CDS             complement(52531..53970)
                     /locus_tag="VH957_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEQ8558388.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDLDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGRA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTMRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            54212..56095
                     /locus_tag="VH957_000447"
     CDS             54212..56095
                     /locus_tag="VH957_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8558389.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSILGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSTDYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            56326..59298
                     /locus_tag="VH957_000448"
     CDS             56326..59298
                     /locus_tag="VH957_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8558390.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKEKVPEKVKEILAKAQQADKQAQELTKMKIPEK
                     IPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLFW
                     KELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVD
                     EYVYKYNLDGLDVDVEHDSIPKVNGKASDENLKRSIDVFEEIGKLIGPKGVDKSRLFI
                     MDSTYMADKNPLIERGAPYIDLLLVQVYGARGEQGEFQNDTKLVTETPEERWQGYSKY
                     IRPEQYMIGFSFYEERAGSGNLWYDINSRKDDDKANGINTDITGTRAERYARWQPKTG
                     GVKGGIFSYAIDRDGVAHQPKQIAEKDKQNVKNNQPQIPEITDNIFHSDYSVSKALKT
                     VMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNK
                     FKKLAQLDLIGLSRITKLDQSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLK
                     VSGLTGLKELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLS
                     TISNHVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVAEGNIDLQSQLLFGTVTNQGT
                     LINSEADYKAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATD
                     KEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADSQAALKAFDG
                     VIEYNPISTQNRASIIFEMKDPSLAKYWRLFNDSSKGEDDYIKEAKLEVFTGQLNAEA
                     DVKTSLEKSDDWQTVSTYSGQEQVFSHALDNISAKYWRVTVDTKGGNYSWPSLPELQI
                     LGYPLPNADTIMKTVTTAKELSQQKDKFSQKILDELKIKEMALETSLNSKIFDVTAID
                     ANAGVLKDCIEKRQLLKK"
     gene            59562..60446
                     /locus_tag="VH957_000449"
     CDS             59562..60446
                     /locus_tag="VH957_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8558391.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIAQT
                     IAYFKTFEADLAGMAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     LHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            60541..61494
                     /gene="manA"
                     /locus_tag="VH957_000450"
     CDS             60541..61494
                     /gene="manA"
                     /locus_tag="VH957_000450"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEQ8558392.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
BASE COUNT        18748 a        10786 c        12915 g        19108 t
ORIGIN      
        1 ttatgctagg aattgtggta taatggagga gtataaaaaa tattaaggag tctattcaca
       61 tggctaaatt gactgttaaa gacgttgatt tgaaaggtaa aaaagtcctc gttcgtgttg
      121 actttaatgt gcctttgaaa gacggcgtta tcactaacga caaccgtatc actgcggctc
      181 ttccaacaat caagtatatc atcgaacaag gtggtcgtgc tatcctcttc tctcaccttg
      241 gacgtgttaa agaagaagct gacaaagaag gaaaatcact tgcaccggta gctgctgatt
      301 tagctgctaa acttggtcaa gatgttgtat tcccaggtgt tactcgtggt tcaaaattag
      361 aagaagcaat caatgctttg gaagatggac aagttctttt ggttgaaaac actcgttttg
      421 aagatgttga cggtaagaaa gaatctaaga atgacgaaga acttggtaaa tactgggctt
      481 cacttggaga tggaatcttc gttaacgatg catttggtac agcacaccgt gctcacgcat
      541 caaacgtagg tatttcagca aacgttgaaa aagctgtagc tggtttcctt cttgaaaacg
      601 aaattgctta catccaagaa gcagttgaaa ctccagaacg tccattcgta gctattcttg
      661 gtggctcaaa agtttctgat aagattggtg ttatcgaaaa tcttcttgaa aaagctgata
      721 aagttcttat cggtggtggt atgacttaca cattctacaa agctcaaggt atcgaaatcg
      781 gtaactcact tgtagaagaa gacaaattgg atgttgctaa agacctcctt gaaaaatcaa
      841 atggtaaatt gatcttgcca gttgactcga aagaagcaaa cgcatttgct ggttacactg
      901 aagttcgcga cactgaaggt gaagcagttt cagaaggctt ccttggtctt gacatcggtc
      961 ctaaatcaat cgctgagttt gaccaagcac ttactggtgc taaaacagtt gtttggaacg
     1021 gacctatggg tgtctttgaa aaccctgact tccaagctgg tacaatcggt gtcatggacg
     1081 ctatcgttaa acaaccaggc gttaaatcaa tcatcggtgg tggtgattca gcagcagctg
     1141 ctatcaacct tggccgtgct gacaaattct catggatcag taccggcgga ggcgctagca
     1201 tggaacttct cgagggtaaa gtattaccag gtttggcagc attgactgaa aaataatagt
     1261 cattataata tatagtaaag ggcatgctga tgcatgtctt tttttagttg atcatgtaca
     1321 gttattgaac tttccctaac ttcacttatc atttactagt ttttagatat agtggtattt
     1381 ggctgacact gcaattttca aaaatttatg acgatttcat atcaattggt ttataaaaga
     1441 tatcctaatc ataaataaaa cgtttaccaa aagggtttta tggattgata tgttaaaata
     1501 gatagtgaag ggataggtat gaaaacgtta agaaaattat tatctaatta caagtttgat
     1561 attaaaaagt ttaaattggg aatgagaaca ttgaaaacag gcttatcggt ctttttagtt
     1621 ttattggttt ttcatttatt tggttggaaa gggctccaaa ttggtgctct aactgctgta
     1681 tttagtttaa gagaagactt tgataaaagc gtgcactttg gcttttctag aattattggt
     1741 aatagtatag gtggcctact ctccttagta ttttttgcat tcaatgagat atttcatcaa
     1801 gctttttggg ttactttatt aattgttcct atttgtacca tgttatgtat catggttaat
     1861 gttgcatgta ataataaatc aggtattatt ggggcagtgg ctgctctttt gattattaca
     1921 ctgtctattc caacaggaca aacgtttatt tatgtgactt cgcgggtatt tgaaacattt
     1981 tgtggcgtct ttgtagctat tttagttaat actgatgttg aacttattaa aaataaatgg
     2041 tttaacaaaa aacacagtga tgttagataa tataacatat atacttgaca ggttattttt
     2101 ttcagcctat aataaggaag atgaaaggag tttgtcatga aagaaaaaga acttagacgc
     2161 tcaatggctg tttttcctat tggaacggtg atgacattaa cagatctctc tgcgagacaa
     2221 attcgctatt atgaagatca aggtttaatt aagcctgaac gaacgcaagg gaatcggcgt
     2281 atgttttcct taaatgacat ggaccgactt ttggaaatta aagatttttt gtctgaggga
     2341 ttaaatattg cagctattaa acgcgaatat gtcgagcgtc aaggtaagtt aatgcaaaaa
     2401 caaaaagctc taacagatgc agatgtcaga cggatcttac atgatgaaat gctgacacaa
     2461 agcggttttt ctactccctc acagcatatt ggtaattttc gtatttaaga tatgaattgt
     2521 ataaaattta aaggagacct atttaatggc aatcacagta gctgacattc gtcatgaagt
     2581 caaagaaaaa aatgtaacgt ttcttcgctt gatgttcact gatatcatgg gcgttatgaa
     2641 aaatgtggag attcctgcaa cgaaagaaca gttagacaaa gtattgtcta acaaggttat
     2701 gtttgatggt tcatctatcg aaggttttgt acggatcaat gagtcagata tgtaccttta
     2761 ccccgattta gacacttgga ttgtttttcc ctggggagat gaaaatggag cagttgcagg
     2821 tttaatttgt gatatttata cagcagaagg aaagcctttt gcaggagatc ctagaggaaa
     2881 tttaaaaaga gccctgaaac acatgaacga gatcggctac aaatcattta atcttgggcc
     2941 agaaccagaa tttttccttt ttaagatgga tgataaaggt aatccgacac ttgaagttaa
     3001 cgataatggt ggttattttg atttagcgcc aattgactta gcagacaaca cgcgccgtga
     3061 aattgtgaat attttaacga aaatgggttt tgaagtggaa gctagtcatc atgaagtggc
     3121 tgttggtcaa catgagattg attttaaata tgcagatgtt ttgaaagctt gtgataatat
     3181 tcaaattttt aagctagttg taaaaacgat tgcccgtgaa catggacttt atgctacttt
     3241 tatggctaaa ccaaaatttg gaatagctgg atcagggatg cactgtaaca tgtctttgtt
     3301 tgataaccaa ggtaataatg ctttttatga tgaaactgat aagcgaggaa tgcagctatc
     3361 agaagatgct tattatttct tgggaggact aatgaagcat gcttataact acactgctat
     3421 cactaaccct acagtgaatt cttacaaacg attagttccg ggttatgagg cacctgttta
     3481 tgtcgcttgg gctggaagta atcgttcacc acttatccgt gttccagcat cacgtggtat
     3541 gggaacgcgt ttggagttac gttcggttga tccgacagct aatccttatt tagccttggc
     3601 tgttctcttg gaagctggat tagatggtat cattaacaaa attgaagctc cagaacccat
     3661 tgaagctaac atttatacca tgacaatgga agaacgaaat gaagcaggca ttattgattt
     3721 gccatcaacg cttcataatg ccttaaaagc tcttcaaaaa gatgatgtgg tacaaaaggc
     3781 actaggttac catatctaca ctaatttctt agaagcaaaa cgaattgaat ggtcttccta
     3841 tgcaactttt atttctcaat gggaaattga ccattatatt cataattatt agacttatca
     3901 ggacctgctc aagttgagtg ggtcttttgg atgagctatt gtatttgagc tagcaagcta
     3961 ttattagctg atcggacacc aattgatttt ccattataga aaactaaaaa ccagtccatg
     4021 ttctatgagg actggttttt agtttgataa ttatctgaac tagaactgat atgttaaaga
     4081 tatagacaga tagtattaag aaatgagtct tatttgattt tagtgcttat caggtgttaa
     4141 gaccatcgga attataattg gttcacgctc agtcttttca tacaagaatg gacgaagagc
     4201 attgacgata gcaccgttaa ctgattggat gctagcatcc ttatttttta aagcaatacg
     4261 gatagcgtta aagagcacac gttggctttc gcggatcaag tcacctgact cacgcatata
     4321 aatgaaacca cggctcagaa tatctggtcc agctaaaatc atttgtgtgt taaaatcaac
     4381 agttgcaaca gctaagacaa caccatcttc tgacaaatca cggcggtccc gtaaaacggc
     4441 tgctccaata tccccgatgc cattaccatc cacgtagatg tcttgggcat taaagtgacc
     4501 agcaatacgc gcactgtcac tggttaaagc tagaacgtct ccattttcca taataaagat
     4561 attttctttt ggaataccaa tatccatcgc cagtcctgca tgaacttttt gcatgcgata
     4621 ctcaccatgt actggcatga aatattttgg tttaatcaaa ctaagcatga gcttttgttc
     4681 ttgctgtcct ccatgaccag aagtatgaat attattgact tttccatgaa taacatcaac
     4741 accagcttct tggatggtat tgattaattt attgacactt gtggtattac cagggattgg
     4801 acttgatgag aaaatcacag tatcaccagg ctgtaaagtt acttgacgat gagtgccatt
     4861 agcgatacga gcaagtgctg ccatagactc accttgacta cctgtacaca taattaaaac
     4921 ttcactagca tgaagatttt taagttcgct tggctcaatg aaggtacctt ttggaacttt
     4981 aatatagcca agttcaatac cgttaacaat tgctttttcc atagaacgac caaaaacggc
     5041 aattttacgt cccgttttaa cagcagcttc tgcagcctgt tgcaaacggt agatgtttga
     5101 agcgaaggaa gcaaaaataa tacgcccatg aataccttcg ataattttta aaatggattg
     5161 gccaacaact ttttcagagt tagtaaaggt tgggatttca gcattagttg agtctgataa
     5221 taagcaaagg acaccttctt caccaagcgc tgccatacgt tgtaaatctg caggatctcc
     5281 tactggcgtg aagtcaaatt taaaatcacc agtacagata atcttacctt gaggggtgtg
     5341 aataacaata ccgaccggtt ctggaatgga atgagtagtc ttgaagaaag tgacgctcat
     5401 gtttttaaaa gttaactcgg tgttgtgatt gatttcgtaa acagttgctt cacgccaaag
     5461 accatgttct tccaatttac cacggataag agcaagtgct aaaggtcctg cgtagatagg
     5521 gatattagcc tgtttgagaa gaaatggaat accaccaatg tggtcttcgt gaccatgtgt
     5581 aataacaaga gctttgaccc ggtctaagtt atcgacaatg taagaatagt ctggaataac
     5641 gtaatcaatt cccaaaagat catcttctgg gaatttgata ccggcatcaa cgataatgat
     5701 ctcgtcttga tactcaatac cataagtatt cttcccaatc tctcccagac caccaatggc
     5761 aaacacccca acttcattag gttttaaact gatatttgtc atcttagaac tccgttaatt
     5821 caaaaacacc ggtctctttt tcgtaatcga ggtgtttgtc agaaagtagc tcgataaatt
     5881 ccacgttata ataggtgtta tcttcaacga gacgacgagc cttgatacgg ccatcgagtt
     5941 catcagtagc atcaatatta agatagagtg ctttagtact ttcacgacgt gggctttgat
     6001 cctttgtttc ttgatagaaa actttataaa tcatttgttt tttttccttt cgttatgaat
     6061 caattatcca aacaataata aataggtcaa aaggtaggtg ttccattttg acggttttat
     6121 atgttgtcat tattgtgtag tagattaatt cctgattctg tgcaattatt gcaattatac
     6181 cataaactta gcttttagta aaaaatttag gtacatttat ggtatagtct aaatcaaatt
     6241 aagagtcagc ctttttgttt atgattctta atttgtgtta taattgatac tagaacttgt
     6301 agtagaaagg cataaaatga agacacttgc atttgatacc tcaaataaaa ccttgtccct
     6361 tgctatactt gatgatgaga cacttctagc agatatgacc cttaacattc agaaaaatca
     6421 tagtgttagc cttatgcctg ctattgattt tttgatgact tgtactgatc ttaaacctca
     6481 agatttagaa agaatagtgg ttgcaaaagg ccctggatct tacacaggtt tacgagtggc
     6541 agttgctact gcaaaaacgt tagcgtacag tttaaatatt gcattggtcg ggatttcgag
     6601 tctatatgct ttggctgcgt ctacttgtaa acagtatcca aatactttgg tggtgccatt
     6661 gattgatgct agaaggcaaa atgcgtatgt aggttattat cggcaaggaa aatcagtgat
     6721 gccacaagcc catgctccac tagaagttat tatagaacaa ttagtagaag aagggcagct
     6781 gatttttgtt ggggagactg ctccttttgc tgagcaaatt caaaagaaac tacctcaggc
     6841 gatactactt ccaaccctgc cttctgctta cgaatgtggt cttttggggc aaagtttggc
     6901 accagaaaat gtagacgcct ttgtccctca atatctcaag agagtggaag ctgaagaaaa
     6961 ctggctcaaa gataatgaga taaaagatga tagtcactac gttaagcgaa tctaatatga
     7021 aaacagttga agaacaagca aaaaatattt atcagctttt ggaaatggtt tatggcacgt
     7081 ctccttggac tttagaacaa gtattaatcg atatatggcg ggatcaaaca gattatttcc
     7141 tactatatga tcacgataaa ttgctaggtt ttttagctat tcaagattta gctggtgaag
     7201 ttgaaatgac tcaaattgct atactaccta gtcatcaagg acttgggcta gcgtctcaat
     7261 tgatgacgca tttaggtagc attgaaagtg acatcttttt agaggttaga gaatctaatc
     7321 atagagcaca aggtttatat cagaagtttg gttttaagtt tattggcaaa agaccagact
     7381 actatagaaa tcctatagaa acagctttat tgatgaaacg ggaaggaaaa aatgacagat
     7441 aggtatattt tagcagttga gagttcttgt gatgagacca gtgtagcgat tttaaaaaac
     7501 gaaagtaccc tcttaagtaa tgtcattgca agtcaggttg agagccacaa acgctttggt
     7561 ggtgtggtgc cagaagtagc tagtagacac catgtcgaag tgattacgac ttgctttgag
     7621 gatgctttgc aagaagctgg catcagtgct tcagatttat cagcagttgc ggtaacttat
     7681 ggtcctggac ttgttggagc cttgttagtt ggattagcag ctgcgaaggc ttttgcttgg
     7741 gcaaatcatt tacctttgat tccggttaat catatggcag gtcacttaat ggcagcgcgt
     7801 gaacaaaagc ctttagttta tcctttaata gcactgttgg tttcaggagg acacacagaa
     7861 ttggtttatg tcccagagcc aggggattat catattattg gcgagacgcg tgacgacgct
     7921 gttggtgagg cttatgataa agttgggcgt gtgatgggct taacctatcc ggcaggacgt
     7981 gaaattgacc agttggctca taaaggtcaa gatacttatc atttccctcg tgctatgata
     8041 acagaagacc acttagaatt ttctttttca ggactcaagt ccgcttttat caatcttcat
     8101 cataatgcta agcaaaaagg cgatgaactg attctagaag atttgtgtgc atcttttcaa
     8161 gcagctgttc tagatatttt attggccaaa acaaaaaaag ctctgagcag ataccctgca
     8221 aagatgcttg tagtggctgg tggtgtagcg gcaaatcaag gattacgaga tagattagca
     8281 caagaaatta cacatataga agttgtgatt cctaaactaa gactctgtgg agataacgcg
     8341 ggtatgattg ctttagcagc agctattgag tatgacaaac agcattttgc taatatgagc
     8401 ctaaacgcga agcctagttt agcttttgac cagtttccag acagttttgt aataaactag
     8461 tcacacttgc tagttagtaa gatttataat ggataagaat ctccctttga aaaaacaacc
     8521 cggtatcttg gcataccggg ttgtcatgat gataagtaat tggcttctat ggttactaat
     8581 aattcagata attacctgca aaataattgt ctgcctaagg tgaagtaagc ttaccagcta
     8641 gctttagtga cgccaggaag ctgtcctttg tgagctaagt cacggaaatt gatacggcta
     8701 acaccaaact tacgcatgta agcatgagga cggccgtcaa ttttgtcgcg gttcttcaag
     8761 cggtttggat ttgaatcacg aggcaatttg cgcagtgatt cataatcgcc cttcgctttt
     8821 aagtcacgac gaaggtcagc gtactgttca atcagttgga gctgcttttg gtatttagca
     8881 atttttgact tttttgccat tgctttctcc ttcttaatat ttaataacct cagagtcgtt
     8941 atcagcgctc tgaatccact taactggtat ttaactggtt aagtggatat ataatcatta
     9001 tacaataaat aaaagcaaaa gcaaataaaa aaaattaact agttatcttt tttagccata
     9061 atatcaaaaa actccacatc taagtgtggg agtcaggtat taataactgt ttaaaggtgt
     9121 ttaatgagtg tcgctttggc aactttgaga ttgaactttt aagtcaaata aatcagcagg
     9181 aacgtagtgt ttggttgaga ccaagatgtc tttaccattg tagagagttt cttggattaa
     9241 aataaaagca ctattttctg atagagtata cttagttgct gtgtaattgc cagtcttggt
     9301 atagccgatt tggttgcagg aatgagaagc tttaccagat tcatagattt tctcttctaa
     9361 gaaagtaaga aggggctctt cttgattgag atttatagca tatttagaaa taacctcaat
     9421 agggataaaa gataaactat aagcaatagc tttattttgg ctatgatacc agcgatcaac
     9481 aataatcaca acaggagttt cttgttttag ggatgctgta atggcaacag tgggcacttc
     9541 aatccgatat tccaattcaa cctttgtgat gtcagatgat aggcttgcat atatggggtg
     9601 ttgaagatat tcgaaacctt ggtgatattt agtttcagga gtcttgagta taaaatttcc
     9661 ctttcctctg atatttttta tgagatgatc ctcttggagg agggctaggg atttacgtag
     9721 tgtcatccga ctgacattga gctgtctagc aagttcaggt tctgatggca gttgcatgcc
     9781 aggactatat gtaccatctt gaataagttg aaaaatagta ttatatactt gcacatgttt
     9841 aagttttttg agttttttgg ttaagtcgtt agtagacata tcacttacct catttaataa
     9901 tctttagtgg agtttaactt gtctaaaaac tattttagca ctaacagtat ttcttgatta
     9961 gaattgtacc catctatagt gttagtatct cacactcagg tactttttgt caaaaaagag
    10021 atgaaaaaca ccttaaaaaa gcgtttacaa aatagagtgt gtgtgatact atacaagtgt
    10081 atcaaaaatt agacaagtaa aatacaggag gtttttaaca tgcaaaatta ttcaggtgaa
    10141 gtcggattgc aatatcacct acagattcgt ccaggtgatg taggtcgtta tgttattatg
    10201 ccaggtgatc caaaacgttg tgcaaaaatt gcagaacatt ttgataatgc agttcttgta
    10261 gcagacagcc gtgaatatgt tacgtataca ggtacattaa acggtgaaaa agttagtgtt
    10321 acttcaactg gtattggtgg tccatcagcg tctattgcga tggaagaatt gaaactctgt
    10381 ggcgctgata cctttatccg tgttggaaca tgtggtggta ttgaccttga tgttaaaggc
    10441 ggagacatcg ttattgcaac tggagctatc cgtatggaag gtaccagtaa agaatatgct
    10501 ccgattgaat ttcctgctgt agctgacttg gaagtgacaa atgctctagt taatgcagct
    10561 aaaaagcttg gttatacaag tcacgcagga gtagttcaat gtaaagatgc attttacggg
    10621 caacatgagc cagaacgtat gccagttagt tatgaattat taaataaatg ggaagcatgg
    10681 aaacgtctgg gaacaaaagc gtctgaaatg gaatctgcag ctctttttgt agcagcaagt
    10741 catctaggag ttcgttgtgg atcagatttc cttgttgttg gtaatcaaga acgcaacgct
    10801 ttgggtatgg ataacccaat ggctcatgat acagaagcag ctattcaagt tgctgttgaa
    10861 gcactccgca cacttattga aaatgataaa tcacaataag cgaggttttg gaagtcatca
    10921 tgcaatttat ttatagtatt attggtattt tattggtatt aggaattgtg tatgcaattt
    10981 ctttcaatcg taagagtgtt tctctaagtt taattggaaa agctcttatc gttcaattca
    11041 ttattgcgct aatcttagta cgtatcccac taggccaaca aattgttagt gttgtttcaa
    11101 ctggagttac tagcgtaatc aactgtggtc aagctggttt aaattttgtg tttgggtcat
    11161 tagcagatag tggcgcaaaa actggtttta ttttcgctat tcaaacgctt ggtaatattg
    11221 ttttcttatc tgccctagtt agtctacttt attatgtggg aatccttgga tttgtagtaa
    11281 aatggatagg taagggcgtt ggtaaaatta tgaaatcctc agaggttgag agttttgttg
    11341 ccgtagctaa tatgtttctt ggtcaaacag acagtccaat tttggttagc aaatacctag
    11401 gtcgtatgac tgatagtgag ataatggttg tgttggtatc aggtatggga agtatgtcag
    11461 tttctattct tggtggctac attgcattag gcattccaat ggaatatctc ttgattgctt
    11521 caacaatggt tcctattggc agtattctca ttgctaaaat cttattgcct caaacagaac
    11581 ctgttcaaaa aattgatgac attaagatgg ataataaagg taataatgct aatgtgattg
    11641 atgcaatcgc tgagggtgca agcacaggtg cacaaatggc tttctcaatt ggtgctagtt
    11701 tgattgcctt tgttggttta gtttctttga ttaatatgat gttaagtgga ttgggaatcc
    11761 gcttagaaca aatcttttca tatgtttttg ctccatttgg ttttcttatg ggatttgacc
    11821 acaaaaacat tcttctagaa ggaaaccttc ttggaagtaa gttgatttta aatgagtttg
    11881 tttcgttcca acaattgggt cacctaatca aatctttaga ttatcgtaca gcattggtag
    11941 caactatttc actctgtggt tttgctaatt tatcaagttt aggtatttgt gtttcaggta
    12001 ttgctgttct ttgcccggag aaacgtagca ccctagctcg acttgttttc cgtgcaatga
    12061 ttggtggtat tgctgtaagt atgcttagcg cctttatcgt cggtattgta actctattct
    12121 aaacgttgac aaaagaaaga aggatagtaa cgtggaagta aaagatattt taaaaacggt
    12181 agaccatact ttgctagcaa caacagcaac gtggccagaa atccaaacaa ttttagatga
    12241 tgccatggct tatgaaacag cttcagcatg tattccagcc tcttacgtca aaaaagcagc
    12301 agaatacgtt tcaggtaaat tagctatttg tactgttatt gggttcccaa atggctatag
    12361 tacaactgca gcgaaggttt ttgaatgtga agatgctatt aaaaatggtg ctgatgaaat
    12421 tgacatggtc attaatttga cagacgttaa aaatggggat tttgatactg ttgaagaaga
    12481 aattcgtcaa atcaaagcta aatgtcaaga ccatatctta aaagttatcg ttgagacatg
    12541 tcaattaact aaagaagaac ttatcgaact ttgtggagtt gtcacacgtt caggtgcaga
    12601 ctttattaaa acctctactg gtttttcgac agcaggtgct acatttgaag atgttgaagt
    12661 gatggcaaaa tatgtcggcg aaggtgttaa aattaaggca gcaggtggaa tctcatcatt
    12721 ggaagatgct gaaacattta ttgctttagg agcttcacgc ttgggtacta gccgtatcat
    12781 caagattgtt aagaacgaag ctacaaaacc cgatagctat taacttaatc ataccgattt
    12841 agcttgagac taaaacaaaa aactcatgta ataggagtta aaaagcctac tatcttagtg
    12901 ataataggct tttttagcta tgaagacttc cctgcgatcc atcctgaaca aagagctgag
    12961 gtaatattaa accctccggt gtgagcatta atatctaaga cctctccagc gaaatacagg
    13021 ccaggaactt tcttactttc caaggtttta ggattgattt cttttaaatc cacgcctcct
    13081 ttggtcacaa aagatttagc caaagacatt tttcctgtaa tgggtatctg gaggtgtttg
    13141 agtttatcaa gcaattcctt ttcttgtttt ggagagagtt gtttgacctt ttcggggtaa
    13201 tcttctgata aaaaatcagc tactcgttca ggcagtaggc ctttaagagc atttttgatg
    13261 tttttatcac gttgatcact cagataagcg gttaagtcat ctgttgataa gtgtggcaaa
    13321 aagtccagct ctgcaatttc cccacctttc acaaaagagg acagacgaag agctgcaggt
    13381 cctgaaaggc caaagtgggt gaagagtaag tcgtgtgtga tgacgtgttt gtcataacta
    13441 agagtaacgt cgtctaggga aataccttgc aagactttgt gaggaaaatc agttaacaga
    13501 gggctctcag cagcttctaa atcagtcact gtcaatttaa aatgccgtgc aatatcatgt
    13561 ccaaaacctg ttgaacccgt tgaagggtag gacttgcctc ctgtggtcac aactaattta
    13621 tgacagctaa aagtctggtc tgcagatttg aggtagaaga ggtcatcttg ttttttaacg
    13681 gaaaccactt cagtgctggt tagtaccttg cctccaagag ccttgatttt tttctccaga
    13741 gcatcaatga ttgtcctaga tttatctgtt gtggggaaca tccgtccatg gtcttcttct
    13801 ttgagtctga cgccgttttc ctcgaaaaag gcaatgatgt catggttgtc aaactgggaa
    13861 aaaacactat ataaaaagcg gccatttcca ggaatgcctg ccataaggtc atcaaggtta
    13921 ccactattag tgacattaca gcgtccacca ccggttcccg ctaatttttt gcctaagcgg
    13981 cgattttttt caattaagag agttttatag ccatagtagc tgctggagat ggcggccatc
    14041 ataccagcag ggccacctcc aataataatc gtatcgtatt gagtcatagc cttattttag
    14101 cataaaagcg ggggatttaa tagtcaggta aatgaactaa cctggcatac cgttttctat
    14161 tcatctaaca atgttttcaa gaaataattg atgcctttag cacgactgaa atgaggtcaa
    14221 attgacagaa tactcctatt atggtactat ttttaataag aatattcagt gatagtgata
    14281 aagaggaaaa tatgggaatt gaaaagacag ttagtgaact agctgatatt ttgggagtga
    14341 gtcgtcaggc cgtcaataat cgtgttaagt ctttacccga agaagatctt gacaaaaatg
    14401 aaaaaggcgt tactgtggtt aagcgcagtg gtcttgttaa gctggaagag atctataaaa
    14461 aaacaatttt tgacgatgag cctatcagtg aagaaacgaa acaacgtgag cttttagaga
    14521 ttcttgtgga tgagaagaac actgaaatca cgcgccttta tgagcaactc aaagccaaag
    14581 atgctcaact tgcctcaaaa gatgagcaaa tgcgtgttaa agacgtgcag atcgctgaaa
    14641 aagataaaca attggatcag cagcaacaat taactgctaa agccatggct gataaagaaa
    14701 ccctaaaact agaattggaa gaagctaaag cagaagccaa ccaagctcgc ttacaagtcg
    14761 aagaagttca ggctgaagtt ggccctaaaa aaggcttttt aacccgcttg tttgcgaaat
    14821 aatcacaaaa aatgacgaag gccctatcag ggtctttttt ggaggaaaac atgaaacact
    14881 tagatactta tattgccttt gatttagaat ttaacactgt caatgacgtt agtcatatca
    14941 ttcaagtatc agcagtcaaa tatgaccacc ataaagaagt tgacagcttt gacacctatg
    15001 tttacacaga tgttccctta cagagcttta tcaatggcct aacaggaatc acatctgaca
    15061 agattgctgc ggcaccaaaa gtagaggagg ttatggctgc gtttaaaaat tttgtgggag
    15121 agttaccact gattggttat aatgctcaaa aatctgacct gcctattcta gctgaaaatg
    15181 gcttggattt aagggaccaa taccagattg acctctttga tgaagcttac gatagacgta
    15241 gcgcagactt aaatgggatt gctaaccttc gtctgcaaac agtggcaacc tttttaggca
    15301 ttaagggtcg aggtcataat agcttagaag atgccagaat gacagcagca atctataagt
    15361 cttttttaga aacagataca aacaaagcat atctcagcca gcaagaagag gtaaccacag
    15421 ataacccttt cgcagctttg ggagactttt tcgactaaag gctctgctat ttttgaaaaa
    15481 taaaaaaatc cctagggtta gcccttgctt ataacgctag gtcatgtgat aagctaggga
    15541 catatcaaga gggagtcgag tgcacacgaa tcgtttttga tcactaaatg atagaaagaa
    15601 ggtgtggaaa tgtctcaatt ctattcgact ggagaactgg ccaacttagc tggcgtttct
    15661 attcgaactg tccaatacta tgaccaacgt gggattttga ttccgacagc attgacagca
    15721 ggtggacggc gactatatac ggattctgat ttagaacaat tacgcatgat ttgctttctg
    15781 cgcgatttgg gattttccat tgagcagatt cgcaaagtct tagcagagga aaatgcagcc
    15841 caggtgctgg aattgcttct agttgatcat attgcgactg ccaaggaaga cttggccgca
    15901 aaagagcaac aagttgacat agctgtcaag atacttgaca gacttcgaaa acaagacccc
    15961 cagtcactag attttctgat ggacatttcg cttagcatga aaaatcaaaa agcttggaaa
    16021 aaattacaat ggaagatggg tatcagtata tttttagcca ttgtttcata tgtaggactt
    16081 attttactat ctaattatct gcaaaaattt tggttagttt atgttgctat gggactattt
    16141 ctaccaggtt tcagttggtt ggtaatttat tttaggaagc aatttattta tctctgtccc
    16201 cattgtcatc agaaatttga acctagcttt aatgaatttg cccttgcagg ccatacacca
    16261 cgaaccagaa agttaacctg ctcccattgc catcaaaaat cgtattgctt ggaactggca
    16321 aaagaggaca ctgtctcaag aggataagca ctaactcata aaaaaactag cctgagatcc
    16381 ttctcaagct agtttttgtt tttttagaat ggtaatttac cagcaaaagc gcctaatgtt
    16441 ttcttagttg cttcatcaat ttgcgtaagg gcatcattaa tggcttgtgt ggtcatgtct
    16501 tgaagcgttt ctacatcttc aggatctaca acagcttctt tgaagtcaat cccaaccaat
    16561 tttttatcac ccgtgaaagt ggcagtgaca aggtcttgag ctgattttcc agtaaattgc
    16621 atagcagcca aatccgcctg cttttgctcc atttgtttct gaagcttttg tgcctgcctc
    16681 atcatattct gcatattcat cataagacta tactctcctt aatttaatac taactattat
    16741 aacatataaa aagaggcaat aaaaacaatg tcagttagta gactagcctg tatcagtaag
    16801 aaagtcgcta tggataagat ggattagcag caagggtctg gctaatgaca gaataagtct
    16861 agaaatgaac tatttttgtc atagactagt ccgacttagt ggttatctaa ttcacgatct
    16921 tctttagctt gttgttctaa aagaatttgt gcgaagtcaa cccacttagt gtagttattt
    16981 tcggataatt gttctgaaat catcgctaac tctcgttgtg gcaactgata agagactccc
    17041 ttactttcta aggttaaatc ttcttccatt agggcggtta aactaacatc aaagatagca
    17101 gcgatatcac ttaatagacc agactttgga gtatattttc ctttttccca ctcactgatt
    17161 gaagaagagc tttttcgtcc taggagatta gcaagttcta attgttccat gttctttttt
    17221 aatctaaggt actttaaatt acttgcaaaa aaagttttct tggcggacat atttttctcc
    17281 ttttctttat ataaaatatg ataccataaa agaggttaaa gcaaaaggta tcgtaaaaga
    17341 tggtctaaaa actctctaaa aacttgactt cataaaaacc gaagtttata ataaacttaa
    17401 catgattaac taatctcatt ttagtgtgga gggaaaattg tgaccaaatc aactttaaaa
    17461 gagttaagaa caacaaagaa aatgacacag caggaattgt ctcacttaac aggtatttct
    17521 gtcagaacga ttgctaggta tgaaaaagat actaaaaagc taaggcgagc aaaatatgag
    17581 aagctaaaag gtattgcaca agcattagcg gtttccgttg atgatatttt tttaggaata
    17641 gattcggaat ttatgaactg agacgatcgt tttctgtttg ctattagtaa gaccaattaa
    17701 caaaaaagtg cttagttata ttgctaagca cttttctttg ttaatttgat gctattggca
    17761 caatcaattg agactgactg agatcaatag ttaaagtata gttgctgttg tcacggacag
    17821 tatgttcaaa atcggttgtg tataagatga ctcgaagagt atttcctttt tctagatgat
    17881 agatagttgg ttgcaaagga agtctaacag tcatccattt attattagga atagtttcaa
    17941 ttgacgacaa attattgcga ttttgtaaat tcatgaaacc tttcgaaata acacggtaag
    18001 aatcttctct aaatggtagc tctttaaggg gttctctaga gaaattttgc ccattgtcaa
    18061 tacttgattg ggtgagagca atgggaagat cacccaagcg ttttttctta ccatagtcaa
    18121 ggatttgtgc agatagaagt cctttatttt cacttgattt cacttttaac tgtaggacaa
    18181 tttcaccgtt aataggtaag tcctcttcca gtaaaatatc aaccagggct tgattggcct
    18241 tgcctttaaa gagagctgct ttgaacgcac ggaaatcttt accgtaagct ttaaattcat
    18301 cttcaccata gtgattatca attaaaagca gttcctgacc gaggtcaagc tctttgatgg
    18361 ttgaggtttc aaagacttta cgctcctgcc agttttgtgg gcaggtgtta tcctgccaga
    18421 tcatttcagg aaggctaaaa tcattagcta ggcctaagag tttttgacat aaaagggcat
    18481 tcatgctttc gcgaaaatca atggattgcc aattatgcat gtaaacatgc tcaccttgat
    18541 gtaaaaagag gtgcttgttg attgtggaag gaagcgcatt gacaatctca tagacctgtc
    18601 ttggtttgac attccagtct tgtaagccat gagtataaac gacatcacac tttatttgat
    18661 gagcattttt taagtaattg cggtcgtgcc aaaattgatt ataatcacca gattgtcggt
    18721 ctaacgcttg agactgttgg tttagcaatt cttgataacg atcattatgg cgaagataat
    18781 cgccagccaa taaattacgc gagtaagtga gctcagttag gacatctaga tcctctccag
    18841 gatagccacc aggactacaa actaagccat tttcgcggta gtagttgtac caagaagaaa
    18901 tagctgattc tgcaataatc atggctaatc cgtctacgcc tgtagtggct aaaccagtag
    18961 acatagttcc caagtaggac tttccagtcg tacaaactag accatttgcc caatcagctc
    19021 tcacttggtg ggtttttgag tggctggtgt aggctgtggc tcttccattt agccaatcaa
    19081 taacggcttt aaagctttca atttgagcat agtctccact cgtcataaag ccagtggaac
    19141 cagcagttcc cacacctgaa acatagatat tagcaaaccc acgtgcgagg aaataatcgt
    19201 tgaggctata ggagttaatg tagctaaagc tttctagatt ttgacctata ggaagtttgc
    19261 aaggctgtgt ctcaagagga ataaaatccc tgtcttcgac agtgatttgt ctcctttttt
    19321 taacgactaa ctctttttcc atacgataaa gttttttgtc gttggctact tcattgatac
    19381 cttgatggta tggactaggt gtcatcaaag ttggtaatgg tttttgagat tgaggacgaa
    19441 tgatattagc cttaataaga tcaagttggc catcttgatc ggtatcaaga ggtgcttcaa
    19501 cgtaaacaac ttctcgaatc agctgtgacg tgtcaaaggt agctaatgat ttaccgttga
    19561 agaaatggta atcattgtcc atagtaagca ttccttggct gaccaaatca tcaatcaggg
    19621 tcatgccaga cttacaacgg gtcgctaata agtggtggat atgcttgata atttctgttt
    19681 cgtcaaagtg gataggaaag gccagtttat caaggaaagc atcggcctct gtaaaatcaa
    19741 ctccaggaat aaagccaagg acttgcaggg ccagtaaatc aaaaacctct ttggataact
    19801 cttgctctga ttgaaaaaag ctcaatgcgt ccatgtcatt tttggcgatt agatgactta
    19861 aaggataatc actatcaggg tagtggaaga agagtttacg taaaaagctt tctaggttag
    19921 ctttggcagt tttttgcaga tccagatcaa agcccaattc ttttaattct tcagccgctc
    19981 tttctagact agttggaata taggaaaatt gattatagcg cataggagtt tcctttctag
    20041 tggcttagaa aacgatatta tcttttaatt tatcaagatt ggtaatgata atatgttgtt
    20101 tatcaatgcg aatgatgttt ttttctttca actgttttag aatacggctg acgctgctag
    20161 cggtagaaat gccacagaat ttaccgagtt cctcattagt aatgacaaaa ttaattaaaa
    20221 tttggccatt tggtagttct tcgccaaata gggtcattaa gtcatatatt tgagtagaaa
    20281 tggcaccgat acggccgtta gttaacatac attgcatttt tttcatggat ttttgaagac
    20341 gattatggta aaagtccttc acatatcctt gtagttcaat atcttcgttt atatctttta
    20401 aaaatgctga gcggcgaacc ttgtaaaaac tagctttctc tgactcgatg cgaacattat
    20461 aaggctctcc catatctttt gaataaccag tgttgagaac agaagtaatt tcaagtcctg
    20521 taacatatct caaattaaat tccattccat attttgaaag aacactctgt ttcacaatgc
    20581 cgtcttttaa aatataagtg aagtcctctt cgagactttc aaaagtcaag tacttgtgat
    20641 aacttttttc aatgatagga aagttatgat tatcaatata ccgttgcaaa atgtgatgat
    20701 tcacgctttt ctccaaatat tcttttacca atgtataatt tgtatcttca agagaaatta
    20761 acatttgcta atgccctttg atagtaacac ttatattata ccattgaaat atattatatt
    20821 ctgctttttt tgtaaaatgt ttatgaaaat agagaggagt tcattttcaa tggaagaaaa
    20881 attgtttaac aaacattttg tggccatcac agtaataaac tttatagtct atatggtcta
    20941 ctatcttttt acggttatta ttgcctttgt ggcgactaga gagctaggag ctcagactag
    21001 ccaggcagga ttggcaacag ggatttatat tctagggact ttattagccc gtttgatttt
    21061 tggaaagcag ttggaggtgt ttggtcgtcg tttggtttta agaggaggtg ctatttttta
    21121 tctcttaacg accttagcct acttttatat gccaacgatt agcatgatgt acttggttcg
    21181 tttcttgaac ggatttggtt atggtgtagt atcaactgcg acaaatacca ttgtaacagc
    21241 ctatattcca gctcgtaaaa gaggagaagg aattaatttt tatggcttgt caaccagtct
    21301 agcagcagct attggccctt ttgtaggaac ctttatgttg gataatcttc atattgattt
    21361 tcgcatgatt attgtcttat gtagcgtctt gattgggtgt gtggttgttg gtgcttttgc
    21421 ttttccagtc aaaaacatgt ctttaaatgc ggagcaattg gctaaaacca aatcgtggac
    21481 tgtggatagt ttcattgaga aaaaagcctt gtttatcact gcaatcgcct ttttaatggg
    21541 gattgcctat gcttcagttt taggatttca aaaattatac acgtctgaaa ttcatttgac
    21601 aacagtaggc gcttatttct ttgtggtcta tgccttaatc attaccatca ctcgtccagc
    21661 aatgggacgt ttaatggatg ctaaaggcga taaatgggtc ttgtatccaa gttatctttt
    21721 tttagcaatg ggactcttct tgctaggtag tgtatcgtct ggaggaagct atttgctttc
    21781 aggagccttg attggctttg gttatggcac ttttatgtct tgtggtcaag ccgcctccat
    21841 acaaggagtg gatgagcatc gctttaatac ggctatgtct acttatatga ttggtcttga
    21901 tttaggttta ggtgctgggc cttacctctt gggcttgatt aaagatttgg cacttggtag
    21961 tggtgtggct tcctttaggc acttattctg gttagctgct gtgattccac tgatttgtac
    22021 cttcctttac ttgttgaaaa caaagacaag acaggttgtg tcttaaggac aagaaaagga
    22081 gtttagtctt atacttaaat acaaacgtat cttaacagct gtagatagtt cctatgagcc
    22141 gggattagct gtgggtaaag ccattactgt agcgctttga aataatccta gtttgctatt
    22201 cgtacatgtc aataaaaatg actcgcaaaa gccattcgtg aaagagaaaa tgtggcctta
    22261 tttttagtag gtgcaattgg attaacatca gaatatagga tttgtcatgt taagattgat
    22321 ctgttgatag tgagagctaa taaaaaatgt tataatacta tgaaataaag tgataaagat
    22381 aaggtctttt atggtccttt tctttaccgc ttttattatt gtgtgaaaat aacacttaat
    22441 gatcatttta tttattattt tattaccttt acattcatca ataagcctgt taaaatggta
    22501 tttgttatat tttattattt ggaggaaacc agaaaacatg gaaatgacat ggactgtgaa
    22561 atacatcaca gaatttatcg caacggcttt tttgattatt ttggggaatg gagctgttgc
    22621 taacgtcgac ttaaaaggaa caaaaggaca taactcaggt tggttagtga ttgcttttgg
    22681 ctatggctta ggagttatga tgccagcttt gatgtttggt aatgtatctg gaaaccatat
    22741 taatcctgct ttcacagttg gactagcagt atcaggcttg ttcccatggg ctcacgtctt
    22801 acaatacgtt gtggcacaat tacttggagc tatctttggt cagttggtag tggtaatggt
    22861 ttataaacct tactttatga aaactgaaaa tccaaatcat gttttaggct cattctcaac
    22921 gatttcatct cttgataatg gtcaaaaaga cagccataaa gtctcttata tcaatggttt
    22981 cttaaacgaa tttgtaggtt catttgttct tttctttggt gctttggctt tgactaaaaa
    23041 ctactttggg gtagagttag ttggtaaatt gattgaagca ggttacgacc aaacaactgc
    23101 agcaacacaa atttcaccat acgtgacagg ctcattggcg gttgctcaca ttggtattgg
    23161 tttcttagtt atggtcttgg ttacttcatt aggtggacca actgggccag cactaaaccc
    23221 agcgcgtgat tttgggcctc gtttgttaca ccacttctta ccaaaatcag ttcttggtca
    23281 agccaaaggt gattcaaaat ggtggtatgc atgggttcct gtagttgcac ctatcttagc
    23341 ggcgatagta gccgtagcag cgtttaaata cctttatatc agataaaaaa agaactaaag
    23401 cttcttttag actcaagaca agctcgctta aggaacttgt cttttttata tgagttaagc
    23461 gaaatctaat gcaaacttga ctgtcttgta tagcgtattt tgtaaatttt actagacttc
    23521 ttgtaaaaaa gcctctcctc agataagatg actaatgcct ctaaacggtg ttacaaataa
    23581 acgaggcatc cctaacttcc tttatctggt gttgaaacta ttttgcacgg actaaatcac
    23641 tgatagagta aaaaacgatt tttcattttt gttgtaaaat attaaaaacg tctctggtta
    23701 gtgattccca gaaacgttat cttatctatt tgtttgttgc ttatgagagg taaaggagga
    23761 acgaatcagc attccaccag tgaagaaaac gatagcgatg accagaagtt tcaagctatt
    23821 aatatctaaa ttcgttaaga aaaacacagc tagtaaaacg ccaataatac caccagaaac
    23881 aattccagca aaaccatccc aactgacacg gtttgctttg ataaactggc tactagaagc
    23941 tgtcataatc atagctgcat ctagcatcat aacaggcata gcaactgttg ggctaagacc
    24001 cattaatgaa aagaaaatca attctggagc ataattgcct aaccccatag tcatcaagac
    24061 tccaacgata aaattaaaac caattccaac aaaaagccag atgccatgga ggccatgaat
    24121 ggtgtctgaa aggtgttctc ctggatggta gattattcta atgatcatga ttatagctgc
    24181 tatgattaaa agactaccaa ggattcgttg gacagttgga gcatgccagt tttttgtaat
    24241 atgagtccca aaataagctc caataaaggc tgctgcagcc atagcaagta aagttagaac
    24301 ctcaactttt acgacaaaaa taaagcaaag agattgaatg agcaccggaa gcacatgagc
    24361 tacggtcata gtgccaggca attgtctatc gtcagtgact aatttagtta acttaaagca
    24421 cgttgtggta gtagcaaaag accctatccc aagggtgtca agggcatctg ttagcaggcc
    24481 aatccaaaac cccgtccaaa agcgtttaaa aggattgatc ttattttttt taagatgttt
    24541 tactaacata aagaaaataa aaagcattgc cgaaactagc aaagcttgta tcagtctaag
    24601 gataagcatt tcgttcataa agactagttt acaaaaaaaa accttagccg tcaacgtgat
    24661 ttacttcatt aaaacatgcc actatgctta gaagagcttt agttcgatgt attttgttaa
    24721 aattaagcta aaatattaat attgcatgaa aggggacgcc ttcctttttc ccttactgag
    24781 cttagctgtt attgtagtga atgtttaaaa ggctagtttg tcgctcttta tcaaaaatct
    24841 agtaggatga atacgtataa tttcttgtca aatagaggaa ttttgtctat aatagcagag
    24901 gattaggagg aaattatgac tttaatggaa aatattacct ttaaaactcc agtattacgc
    24961 gttaatgatc gcgaccttaa tattgcattt tatcaaaata atttagggct tcgtttagta
    25021 tctgaagaaa atgcgattgc tatcttttca tcttggggag aagggcagga atgttttgta
    25081 attgaagagt caccttcagt tagaacgcgt gcggtagaag gccctaaaaa ggttaatacg
    25141 attgtcatca aaacaaatca acctaaagaa atcgaacaat tattagctca tggagcacat
    25201 tatgacgctc tttttaaagg tcaaaatggc tatgcctttg agactatttc cccagaagga
    25261 gaccgattct tgttgcatgc tgaacaagat attaaacatc tccaaggtac tgatttacca
    25321 tcgcttgaaa aagatgcgac ttttaaaggt ttaactcaat ttaagtttga tattattgtt
    25381 ttaaatgtta ttagtgaaga acgctcaaaa gctttttatc gggatctgtt tagtgatcag
    25441 ttacctatta ctatggattt tattcaagaa gaaggtcccg atttggcaat tgatccccat
    25501 attgcttggg atttagaaat tttagaattt caagtctcaa aggactatga tatgaaggtc
    25561 ctaaaagcaa ctttagaaga agacgggcac aaggtctaca ttgataaaaa acacaaagta
    25621 ttggtccttt ctgatccaag tcagatcgaa gtatggttta cgaaatgact ttggcagtca
    25681 ttaaatgtat tgaaaaccat cttcacaaaa aagtatacaa aggggccagt ctggctctct
    25741 ttcaatctgg tcgatggcaa gaataccata tcggaacaat tgatggaaga cgaccagttg
    25801 atgctaactt agtttatgac ttggctagtg tttcaaaagt tgttggtgtg gccacaatat
    25861 gcaatatttt attgaataat ggtacgttag cattagatga tcccttaaaa gtatattatc
    25921 ctagtattgc tgatacgact gtcactattc gacagttatt gactcatacc agtggtcttg
    25981 atccttatat tcctaacaga gatgttttaa atgcacaaca attaagaaaa gtacttaatc
    26041 atcttactca aaaagaaaat aaaaactttt attacacaga tgttaatttc ctcttgttag
    26101 gctttatgtt agaagagctc tttagtgaat ctttagacca gatatttgat aagactatct
    26161 ttactccctt tgggatgtat catacgtctt ttggccctcg tccagaagct gtaccaacat
    26221 taaagggtgt gagtgatgga gaagttcatg atcccaaagc aaaaatctta aaaaaacatt
    26281 ctggatctgc ggggctattt tcaactcttg cagatttaga aagttttagc aatcattatc
    26341 ttaatgatcc attttcagat tgtctgtggc gcaactacag ccaacaaaca attgagcggt
    26401 cactagggtg gaatttagat ggcgattgga ttagtcatac aggttacaca gggccgtttc
    26461 taatgcttaa taaaaaagag caaacggcag ctattttttt gaccaaccgt acttacgacg
    26521 aggatgataa aagtaaatgg ttaaaagaac gtcagttgct ttacaatgca ctaaagcatg
    26581 atctgacaac acccgtatcg taacgtctaa aggggcagtt ttagtgatct tattactgtt
    26641 tttaaagttt cttctaaaaa atagccattt catttgtctg atgcgattag agtgattata
    26701 agtgaaaaaa gaacagccat ctcattttga atcaaatgag atggctgttc ttttttataa
    26761 gttattgatc atttagatac tactatttac ttgaaatagc ttcagcggca tcatccattg
    26821 aaagcacttc gtggaagaca cgttgagtca attcagtttt ttgttctggt gtaaggtatt
    26881 tggtgttgac acagtaacca gagatacgca cgataacgtc ttcgccgttc atgattttgt
    26941 cataaacatc gttaaggtcc ataacgttca agttaacgtg ctgaccacca ttttcaaagt
    27001 aaccgtcaag cactgttacc aagttgtcaa cttgttcgtc aaatgtttta ccaagagcac
    27061 gaggtgatac ttgagtagtc aatgagatac catcgttagc atgtgagaat tccagtttag
    27121 caagtgagtt aaggttttgt aaccagccac cttttgcttt gttagatggg ttagcacctg
    27181 gtgagaagaa ttccacttgg ctagtgttaa ctgtaccatc ttcgttcaag aagacgccgc
    27241 ggtgaactgg agagttacca gtttgtttag agtaagcaac gtttgaagtg atggtaagaa
    27301 gtgatactga agcctcagca ttcttgtaaa gtttgtggct tgcaagacgt gtgtggtaag
    27361 cttccatcaa ccatttcgcg atgtcatcaa cacggtcgtc atcttcaccg taacgaggga
    27421 agtcacctgt tacttcgtag tcataaatgt agccattttc atcgcggata gttttaacag
    27481 ttgcgtattt aatagctgac aaggtatcaa ctgtgttagc gaaaccacag ataccgaatc
    27541 ccatgttagc acgttggtgt gttggcaaga aggccatttg aactgcttcg tagttgtatt
    27601 tatcagtcat gtagtggatg atgttaagcg catctacata agtatctgtc aaccagtcaa
    27661 gagatttctc aaagttagcc ataacttcgt cgtactcaag gacttctgat gtgattggtt
    27721 caacaacgtt aaacactttg tagtctctgt gaacatcatc gtaaccaccg ttaagaccag
    27781 taagaagggc tttgagaacg tttacacgag caccgaagta ttggatgtta tgacgttgtt
    27841 cttcattttc tgggtcaagt ggtgatacac aacatgaaat acatgacatt tcaccataac
    27901 cttctttagc cattgttgtc acaccttcat attggataga agagtgtttg tggctcattt
    27961 tcatacagta gcgacggaat gtttctggca gttggtcagt ccaaagaact gttaagtttg
    28021 gttctggaga gttaccgata ttatcaagag tgtttaagaa acggtagtcc atcttagtca
    28081 cacggtgacg accgtcgtta cccataccag ccatagaagt tgtgatgaat gttgggtcac
    28141 ctgagtaaag ggcatcgtaa gctttcgtac gaccaaattt tacggtacgg agtttaagga
    28201 caaaatcatc cacaaattct tggatttctg attctgtaaa ggtaccgcga gcaaggtcac
    28261 gttctgcaaa gatatcaaga acgattggca cacgtccaag agaagtagca gcaccgttga
    28321 tcacacgaca tacagccatg aaagcgatgt ttacccattg gatagcttct ttaacgtttt
    28381 gtgctgggcg acgaacatca actccgtaaa ggtcaccaag tttaaccact tcaccaagag
    28441 cttggtattg aaggttaact tcttcgcgaa gacgaatgga ttcttcatcg atttcagtga
    28501 tagcattcca gtcattgact ttttcttgca tcaagtagtc agcaccgtaa agagcaagac
    28561 gagcgtaaac accgatgata cgtccacgtg agtaagcatc tggaagacca gttacagtgt
    28621 gggcatgacg agcgcgacga atatttgaag tataagcgcg gaagataccg tcgttaacag
    28681 ttgtcacata cttagtaaag atttcatgta ctgctgggtc tggttcatag ccgttttctt
    28741 taagggtcgt ttccgccata cggataccac cttttggcat gaagttcaat ttgaacaatt
    28801 catcgttttg aataccataa attaattcat tttctttatc gatgaaacca gcaggaatgt
    28861 cagcaattga agttggacga gtatcgtatg ggaaacgtgt agcttcatag tgtgcttttg
    28921 tttcttcgat aacttttttg atgtgaagtg aacgttcagt agcaccagcc aagaaagatt
    28981 catcgccatc gtatggggtg tagttagctt gtacaaaacg tgagacactt gctttttctt
    29041 tccagtcagt tcctttaaag ccttcccaag ctttttcgaa aacatctgta ttggttttaa
    29101 cagttgccat aaatttctcc ttaaattcta gtaacaaagc gatctgttac atttacaatt
    29161 ctaagtttaa cacataggaa acgttttccc aagcaaaatt cttgacaaaa ttaagattct
    29221 tttataatac agattgttga aacagtcaca aactgtatta gaatgtattt ttttggcttt
    29281 aggtagccta aaaggtataa tagagaaagg agggacttat gcttattttt ccactgatta
    29341 atgacacgtc acgaaaaatc atccatattg atatggatgc cttttttgct gcagttgagg
    29401 aaagggataa ccctgcttta aaaggaaagc ctgttgtgat tgggaaagat ccaagagaaa
    29461 caggtggtcg cggagttgtt tccacttgta attacgaagc gagaaaatat ggcattcatt
    29521 cggccatgag ctctaaggaa gcttatgagc gttgtcccaa agccattttt atttcaggaa
    29581 attatgaaaa gtatcgaaca gttggggacc agatccgccg tatttttaag cgttatactg
    29641 atttggttga acctatgtct attgacgagg cttaccttga tgtgactgat aataagttgg
    29701 ggattaagtc agccgtcaaa atagccaagc tgattcagca tgatatctgg aaagaagtag
    29761 gattgacctg ttcagcaggt gtgtcttata acaaattttt ggctaaattg gctagtgatt
    29821 ttgaaaaacc ccatggcctc accctagtct tgaaagaaga tgccctgtgc tttttagcca
    29881 aactccccat tgaaaagttt catggtgttg gtaaaaaatc agttgaaaaa ctgcatgaca
    29941 tggggattta tacaggacag gatttgttgg cagttcctga aatgaccttg attgatcatt
    30001 ttggtcggtt tggttttgac ctttaccgta aagtgagagg catcagcaat tctcctgtca
    30061 agtctgatcg gatacgcaag tcaattggca gtgagagaac ctacgctaaa ctgctttatc
    30121 aagaaacaga catcaaggca gagatcagta aaaatgctaa gcgcgtggcc gctctcttac
    30181 aagaccataa aaagttaggc aagaccattg tgctcaaagt gcgttatgct gattttacca
    30241 ccttgacaaa acgtgtcacc ttgccagaat taaccagaaa tgccgcacaa attgagcaag
    30301 tagctgggga tatttttgac agcttaagcg aaaatcctgc tggtatccgc ctgttagggg
    30361 taaccatgac caatttggag gataaggtag ctgatatttc cttggaccta taggagaaag
    30421 agggctctat ccgtccgcct cattttggag aaaaaagaag ctgattaggg atttccctaa
    30481 tcagcttctt tggtccatta ttttattaca gcatagcttg gtctgtatca tcaccttttt
    30541 cgttaagggt tttagccttg taaaaagcaa agccataaag agcagcttgt ataaggataa
    30601 ggatagttcc aaccattgac aaggttgttg tgaactggtt aaccaagccg ataacagaaa
    30661 ggataagtcc taagatataa ggaatataac taaccgttaa tccttgtttt agtttggata
    30721 agttttgagc acaaaagaca atgatagcaa taatagcaag gacatttaag acagataaga
    30781 aaatcataaa tggtgtcatg ctgctttgta gctgtgccaa ttgttcagtt gttaattggg
    30841 cccgaaatgc ttcattcttg agttggcttt gtaagtagaa aatccctgca aatcccatta
    30901 atgacagtac aactccaagc ccgtttagaa taataatggc aatagtagac gttttgagtg
    30961 cctgacgcac tttttcataa gaaatcatat aatcctccta gagtccttaa tccgaaattg
    31021 tacaatgtgc ttaatacaaa aatattatac catagattaa tcaaaaatgt ccgtttttct
    31081 aggatttttt ctggaaaaag agggcaatat ctgactctgt aagccctatc atcgaatcga
    31141 tagtcgaata attctcaggt gttaacctaa aatcatcatt atctgactga gagttctcag
    31201 tggggttaga gtttgttgat tgagaggaag atttttgaga gtcgtcctca agggttgccg
    31261 tattagaaaa aagggaggtc tgctcttttg attttagctc ttggttaggt tgagaggagg
    31321 ctaagtcgga ttgttcttgg aagcgttcga tcaagtaggt ttggcgttta tcgccttcgt
    31381 gtttaatagc atactcaaag gcagtatatt ctcccaacag aattaactta cttttagacc
    31441 gagtaatggc cgtgtaaatc acatttcgtt gcaagagtcg gccgctttgg cgtgtgatag
    31501 gtaaaatcac cgcttgaaac tcactccctt gcgatttatg aatgctcatg gcataggcca
    31561 gggttaattt tagccattca tttctagggt acgtgacttc gctaccgtca aaatctaaga
    31621 ttaattcgtc ttgcttagat tcggtgtatt tagcaggaat caaatctgta atataaccaa
    31681 tatctccgtt aaagacattc aactgagcat cgttgactaa gtgcaggact ttatcacctt
    31741 tacgaaaata cgtatcattg aacagaaatt ctgtttgtcc ttgcaaggga ttgagaagtt
    31801 cttgcatgag ttgattaaga tgattgatgc cagcttgtcc tttgtacata ggcgctaaaa
    31861 tttgaatttc ctcagcaggg atgccacttt taatagcaga taggacaatt ttttgaatca
    31921 tgtcagggat aaaggctgct tgggcttcaa aataagaacg gtcagctttt ttatcacgaa
    31981 agtcagcagc taagattcct cgacgcatct gatctgccaa attgacaata gtagattctt
    32041 gggattgacg aaatatcttt tgcaaggcga tttggggcag gctattgact tttaaaagat
    32101 ctgacaggac ttgaccgggt ccaaccgaag gaagctggtc actatctccg acaataatca
    32161 cttgagttgt tgagttaata gctcctaaca actggttggc aagccaggta tctaccattg
    32221 aaaattcatc gacaatcagc aagtcgcagt ctagataatc ctccatggct tggtaatcgt
    32281 tgtcgccatt gaggcctaag tgcctgtgga tggttgcgct aggaagtcca gtcaactcat
    32341 tcatgcgacg tgcagctcga cctgttggag ctgctaacaa gataggaagg tcttttttat
    32401 ccaaatcaat ctgatgcagg ttcgcgtaag cctgcaaaat gcctcgaata acagttgttt
    32461 ttcctgttcc gggaccacct gttaggagaa agaccttgct ggttaaggcc ttagtaatgg
    32521 cttcttgctg cacttggtca taggtgatgg caaagtcttt ttgaacggct tggatggttg
    32581 tttgaatggt atcatgacta aatgactgac ttaaaggggt atctaagaga cgagagatgt
    32641 tgttagcaat cccttcttca gcaaaataaa ggctagcatc aaacagtttg gtgtcactgt
    32701 ttttgatttt gccctctatg atcaactcgc ttagttgttc agccacagca gcaggatcac
    32761 attctacttg acgtgcatct tcaaggagtg tgatggcaaa gtctaataat tgtcgtgctt
    32821 gaacataagt atctcctcga ttgatggatt cttccaagag acaatgaagg agggctgcac
    32881 gaaaacgttt cggagagtcg ctttcaatcc ctaagttttc agcgagagca tctgctattt
    32941 taaacccaaa accttgtaga tcttcgacta actgataggg attttcttta acaaggtcaa
    33001 gagcctcttc tttatacttt tcaaacgctt gaaaggcaaa acggttgcta aggccaagtt
    33061 cgacgagacc agcaatcagt tgctctgtgc cgtaattcaa ttttagttta gcgacaaagg
    33121 cttgacgatt agccttagat aggccagaga tagtttctaa tttacttggg tcttctaaaa
    33181 tatggtcaat agtattatga ccatatagtg caatgatttt ctccgctgtt tttttaccaa
    33241 tccccttaaa atggtcacta gagaaataat taaccaaacc agatgaacta ggtttgattt
    33301 tttggtaacg gcttagcttg agttgttgac cgtatttagg gtgctgggtc aattctcccc
    33361 aaaaggtgta gtcatctcct tcaataatgt cagccatcgt tcctgtgata atgatttcaa
    33421 agtcgtcaat gtcactgtct gtatcctcaa tggcaaggag gagaatttta aagaaattag
    33481 cctggttttc aaaaatgata cgatcaacag tacctgtaaa aacgtattcc atagtaactc
    33541 tttctattta tacaagataa ctgaaaacct gcccaaaggc aggttttttc taattaaaga
    33601 cggtcatttt attgagtggc caaaaacgag ctttcacttc accgataagg ttttcttttt
    33661 tgaaactacc aacttcgcga ctatcccggg aaacaatacg atcatcacca agaagaaggt
    33721 attctccttt tggaacactc atctcaaagc gtgtttgtcc ctcagaatta gttgtaaaag
    33781 catcagatgt ttctgctaac tgttggaata gggtattata ggcgtaagtt ttttggagtt
    33841 tatcgttttt aaattgtttt agatactcag ccaaatacgg ctcaactgtt tttttaccat
    33901 taatataaag tgtgtcatca ttataagaaa tggtatcgcc tggcaatcca ataactcttt
    33961 ttacgatttc tttcttttgt ccgttttctt cttcctgagc aactacaata tcaaagcgat
    34021 caatcctagc ttgattaaaa acgataaggc gttcgccatg agctagagtt gggtccatag
    34081 aatggccgtc tactttaaca gcctgccaca aaaaaagacg agatagacca aagagaatta
    34141 aaaagagagt gaatgggccc cattctttaa taaactgttt catatgattc cttttattta
    34201 gtgagaagcg cttgcgcttt gtgagtgttg gcgaagtgaa gtttagcact atattctaag
    34261 ctagacatac cataagcggc taagagttgg ctagcaactt tatctgaagc tgaaccagca
    34321 ccgcttggga gttggtaacc taaatcttga cctaattgat cgagattgtc taaaaataga
    34381 tttctagcaa tgatagagct aacagccaca gccaaatagt gactttctgc cttttcttga
    34441 aaggttagag gattcgggaa atggtttttt tcctttttta gatgcttttc ataatttgat
    34501 tggctagtga aagcatcaat aacaatttgt ttaggttgaa tgcctttttg taacaacaaa
    34561 aaaatagctt ggttatgaag agcaactttg atagaaatgg cattatatgg tttactttta
    34621 ccaaccaatt cgttatattt tttaggtgat aggagaagtg attgatgagg tatttgtttc
    34681 tctaacagag gcgcaatctg ttgaatggtt ttatccgata attttttaga atcatcaacc
    34741 ccaagctttt tcaggaaggg atgatcttta ggatcgacaa aacttgccac aacagcaatc
    34801 ccaccaaaat aagagccatt acccacctca tcactgccga ttataggtat atcttggcta
    34861 ttgttgcttg cttcaaaaac tgtcttagct actggaagat taagctcttg agctaaagca
    34921 tttgcaccgt ttccctggag aactaatttt ccggatttgt acagcaaaac agtaacccca
    34981 ttttttttag cagcaaaggc tacataggta ttttggctac tgatggtgta gggggctagc
    35041 tgttttttta aatgtttact cagtatagca tctattttca aaactaaggt attcataata
    35101 attattttaa cataaaatag ttgactatgg ttaattcata agtttattta acaaagaaaa
    35161 cagagactcg aatgtttaga cgggttaggg caatggtgtt gactatttta cgaaagtttc
    35221 attttacggt ataatgctaa tgaggtgacc ctatgaaaag tattaatcgc tataaattca
    35281 cctttggtga aaaaacatta acattgacaa ctgacaaaga caatctcttt atggaagaag
    35341 ttgagcgggt agctaaagaa aagtatcagg ctcttaaaaa tcatttacca gaagctgatg
    35401 acgagacaat cgctatttta atggctatca ataccttgtc aacacaatta agcagagaga
    35461 ttgccattga aaaaatggaa gctgaaattt tagatttacg tcaaaaaacc ttggttggtc
    35521 ttcaagaaaa agctaatcaa atagatgtga atgaggttta atcatgttat ctttattgat
    35581 agtgcttgtt ttaacttgga atttttatat tggttatagt agaggtatta ttcttcaatc
    35641 gttttatgtc ttaggagccc tactttctct tttggtagct aatcgatttt atattggatt
    35701 agcccataag ctaacgcttt ggattcctta ttctaacccg gtagaaggaa catcagtctt
    35761 tttctttaaa tcagttgata tctttgtttt agataaggtt tattatgcag gccttgcctt
    35821 ttttatcatt ttcttattgg ggtatgcact gagtcgcttt cttgggattt ttgttcattt
    35881 ccttttgcta gattattttg ataaccagtg gacaaaatgt ttgagtggcg gactagcgct
    35941 tctagtatcg cttctttttt tgaacatgtt actgtctatt tttgcaacgg tccctatgcc
    36001 ttttttacag cactatttgc actctagttt tcttgctcgt ttggtgattg aacaccttcc
    36061 accattgaca ataattattc aaaaattgtg gattcaagcc attatttgat atcgttttgt
    36121 gactaatata agaacctgga gtgagtttca cctttaggtt ctttatttac gagaaactgt
    36181 ttagaaataa agagaacgca tgggaactta gtgactttct tgccacattt tccatcattt
    36241 taggtataat gaagagtatg aataacaaga ttttagagca gttagaattt aacaaagtta
    36301 aggaattgct attaccttat ctcaagacag aacaatccca agaagaatta tcagagctgg
    36361 agccgatgac ggaggctcct aaaatagaaa aaagttttaa tgaaatttct gacatggaac
    36421 agatttttgt tgaacatcac tcatttggca tagtcagcct aagttcaatc tctgagagtt
    36481 taaaacgctt agagctttca gctgatctta atattcaaga acttttggct atcaaaaaag
    36541 ttttacagag ttcttcggat atgattcact tttattctga tttggataat atttctttcc
    36601 aatctttgga tcgtttgttt gaaaatttgg aacaattccc taatctgcaa gggtcttttc
    36661 aagctatcaa tgatggtggt tttttagaac attttgcgag tccagagtta gagcgtatcc
    36721 gtcgtcaatt aacaaatagt gaacgacggg ttcgtcagat tttacaggat atgcttaagg
    36781 aaaaagcaga gcttttatca gaaaatctaa tcgctagtcg aagtggacga agtgtcctac
    36841 cagtaaaaaa tacttatcgg aatcgtattt ctggtgtggt tcatgacatc tcttcttcag
    36901 gaagtactgt ttatattgag cctcgtgctg tagttacact aaacgaagag ataacgcagc
    36961 ttagagctga cgaacgccac gaagaaggtc gtattttaca cgcattttca gacttgttaa
    37021 gacctcatgt cgccactatt agaaataatg catggattct tgggcatctt gattttgtaa
    37081 gggctaaata tctttttatg tctgataata aggcgacgat acctaagatt tctaatgaca
    37141 gcacgttagc attaatcaat gttcgtcatc ctctgttaag taatcctgtg gctaatgact
    37201 tacattttga tcacgattta actgcaattg tcatcactgg tcccaatact ggtggtaaga
    37261 cgattatgct aaaaacactc ggtttagcac aattaatggg acagtctggt ttgccaatat
    37321 tagcggataa aggtagtaaa attgcagtat ttaacaatat ctttgcagat attggcgatg
    37381 agcaatctat tgaacaaaat ctatcaactt tttctagtca tatgacgcac atagtcagta
    37441 ttttaaacga ggctgaccac aatagtttag ttctctttga tgaactggga gcaggaacgg
    37501 atcctcaaga aggtgctagt ttggctatgg ctattttaga acaccttagg ttaagtcata
    37561 tcaaaacgat ggcgaccacg cactatccag aattaaaagc ttatgggatt gaaacaaatt
    37621 ttgtagagaa tgcgagcatg gaatttgatg cagaaacgct tagccctacg tatcgcttta
    37681 tgcaaggagt tcctggacgc tcaaatgcat ttgaaattgc ttctcgcctt ggtttagctc
    37741 catttattgt taaacaagct aagcagatga cagattctga ttcagatgtt aaccgtatta
    37801 ttgaacagtt agaggcacag acacttgaga cacgtagaag actggatcat attaaagaag
    37861 ttgaacaaga aaacctcaaa ttcaatcgtg cggttaagaa actctataat gaattttcac
    37921 atgaacgcga taaagagtta gaaaaaatct atcaagaagc tcaagaaatt gtagatatgg
    37981 ctttgaatga gagtgatact atcttaaaaa aactcaatga taagagtcaa ttaaaacctc
    38041 acgaaattat agatgctaag gcacaaataa aaaaattagc gcctcaagtt gatttatcaa
    38101 aaaataaagt cttaaataag gctaaaaaaa tcaaagcagc tcgtgctcct agaattggtg
    38161 atgatattat agtgactagt tatggacagc gaggtacctt aactagtcaa ttaaaagatg
    38221 gccgttggga agcacaagtg ggaattatca aaatgacatt aacacaagat gaatttagcc
    38281 tcgttagagt tcaagaagaa cagaaagtca aaaataaaca gattaacgtg gttaaaaagg
    38341 ctgatagttc tggaccaaga gctcgacttg atcttagagg taaaagatac gaagaagcaa
    38401 tgcaagagtt agatcatttt attgatcaag cattgcttaa caatatggga caagttgata
    38461 tcattcatgg tattggtaca ggcgttattc gtgagggagt gacaaaatat cttcgtcgtc
    38521 ataagcatgt taagcatttt gcttatgccc cacaaaatgc agggggatct ggtgccacaa
    38581 ttgtaacgtt agggtaaatg atggaatcat atgaacactt ttatgccaaa ctatctcaac
    38641 cttttagaaa aaccccacag ttaataattc ttttaaatgt tttactaaaa ataatcacag
    38701 gagtgatgta catactttat ccatcttttc tgatatttac gctttggcaa gggatgacat
    38761 ttcaattatg gttaaggcta ttaattattc ctgctgttgg ctttatagct ttgtcttaca
    38821 ttaggaaacg ctttgatttt ccacgaccgt atgaaaaatg gaatattaaa cctttaattg
    38881 ataaggatac aaagggaagg tcaatgccta gcagacatgt tttttcagct acgatgatta
    38941 gtatgtgttt gttacgatat tatgtttact ttggaatagt ttgtttaata ttatcggttt
    39001 tattggcaat ttgccgtgtg atagcaggta ttcactatcc taaggatgtt attgtaggtt
    39061 accttattgg cttgatgtta gggctttgtt tattgattta gcgagttcgt agcaaatagt
    39121 ttcaaaaaca actaaattct tgtacaatag gcttatcatt aagatgaaat ggagaaaaaa
    39181 gatggcatta gaagtaacag atgctacatt tgtagaagaa actaaagaag gtttagtact
    39241 cattgatttt tgggcaactt ggtgtggtcc atgtcgtatg caaacaccaa tcttagaaca
    39301 gttatctcaa gaaatcgatg aagatgaact caaaattttg aaaatggatg ttgatgaaaa
    39361 tccggaaact gctcgtcagt ttggtattat gtcaattcca acattgatgt ttaaaaaaga
    39421 cggagaagtg gttaaacaag ttgcaggtgt tcatactaaa gaccaactga aagctattat
    39481 tgctgaattg agttaactaa aataaagccc agcgtcacgc tgagctttat tttatgacct
    39541 actaacttca atggaataac catgtaaaca taaaacgact tgcaaaaaag atggcaacag
    39601 taatgaggaa aaatacagtg acaataaggg ggttctgata aggaagtttt gctctttctt
    39661 ctcgtttttc gatttcgtct aataattttc cacttgaaac agctaggatt tccttataag
    39721 gttgcacatc atattttttc ttaaaacgtt ccacacgatt agcataagtc atagtaatta
    39781 tcgataataa aacaaaaatg ccaagtccta gccactctaa gaaatagact aatggataac
    39841 ttgaaatcat taataatatc atcaatgtta ccattacttt ggtatctcgt ttaaaattct
    39901 ttttatcaac ctgagtgatg gtatatttca ttttctcaat gtctccttta atgagttggt
    39961 ctaagctcac ttgaaaaatt tgacttagga gtaagaggct atggatgtct gggtaagttt
    40021 tgtcattttc ccagttagat atgctctgat ggcttacata gactttctcg gctaactctt
    40081 cttgcgagag cgcttgttgt ttacggtagc gaataatttg ctgaccaatt tccataaata
    40141 tctcctttca taatattagt ataagaatga taagctaacg ggtctatcaa atgtatttga
    40201 cattagggat agatcactat ttataaggta ttaaaagaca atctgaggac aactttacag
    40261 cggcgtaaag gaattgtaaa caaaaagtga accgtcatag ttcacttgtg attaagcatt
    40321 tttctgtttt aagtaggtct ctagcatttt cttttgtggt gttgcaaagg gatacagaga
    40381 aaagtcctca attgctaccc actttaggtg aggagcatta ggtaaatctg ttgctttgac
    40441 caccccctct atgagttcta ttgtccactt ctggtgacta aaagtgtgct taatatttgg
    40501 aaagtgatta tcagtccatt ggggctttaa ttgatattct ctttcgaaag tttcattttg
    40561 ggtttgccag attatggggt tggattgatt gtcatcaaat aaatctaatt gttgagaaag
    40621 aggtgacgtt tcgataatag gaaatgacca aaaacctcct agaagtctcc ctttagtatt
    40681 tttctccagt agatattggc cactttggtt acgaatgaca aaagcctgaa ttcgcattgg
    40741 tttaggcttt ttctttggat tttttatggg atatttacca taagtaccat tcaaataagc
    40801 agcgttaaag aaacgaatag ggctttcatc aggcctaggt gtcttagcgg attcgatgtc
    40861 tgtacctaga tccataagtg cctggttaaa atcaccgggt ctgtcagggt caattagtat
    40921 ttccataata gcttgaaaaa ttttacgatt tttagggtca ccgatatcat aattaacttc
    40981 aaacaaacga gccatgacac gcatcacatt gccatcaaca gcaggctctg gtaagttgaa
    41041 tgagatgctg gcgatagcac ctgcagtata aggaccaatc ccttttaatg aagcaatatc
    41101 atcataagtg tgaggaaata tgccaccaaa atcaaccatc acttgctgtg cagccttttg
    41161 catattacgc acccgagaat aatagcctag tccctcccat gcctttagta attgttcttc
    41221 aggagcgtct gccaaatctt ttatttgagg aaaccactct agaaaatgtt tataataagg
    41281 gattaccgta ttaacttgtg tttgttgcaa catgatttca gaaacccaaa tatagtatgg
    41341 attagtagtt cttcgccaag ggagatcacg tttttcttgg tcataccacc ctaaaagtgt
    41401 gcgacgaaaa gaagcgattg tctcattatc ccacatatta ataccataat cttttaattc
    41461 aatcatgttg ttattgtaac acaggagcct taaaaagagt aaaaaaagat tttaggtatt
    41521 tgcgaaaaag aaaaggaaat attataataa tattaggttt acctcatcta aatgttgatt
    41581 tagaataact gaaattaacg atagaagcag acaggtttta atttggaggg gacatgttcc
    41641 agaaattaaa gaatcttatt gatcggtatt cgtggttcgt ttttataatg atgattcttg
    41701 tgttatttct taactatatt tatccatttg atccttcttt gagcggacta cagttggaat
    41761 ggctgatcat gacgcaagtt tttcctggat taggtatcgt atgtgccatg gttgctatta
    41821 tttttaaaaa gtttaacctt tttgttttgg ccctaatttt atattttgca ctttggttaa
    41881 aacttttcct tgctttttct tttttcacct attttttagg agtctgacta agtgccaatt
    41941 tttaaaactc gtgaaagaaa atgtttgaca aaacttagtc aagtagaaaa agttccttgc
    42001 ttttaattga ctattagtgt acaataagat tctgtgagta tacctcactt actcactcca
    42061 aaagtagtga gtcattagac caaaaggagg aaaatatcaa tggctaaata cgaaattctt
    42121 tatatcattc gtccaaacat tgaagaagaa gctaaaaacg ctttggtagc acgctttgac
    42181 tctatcttga ctgacaacgg tgcaaatgtt gttgaatcaa aagattggga aaaacgtcgt
    42241 cttgcatacg aaatcaacga tttccgtgaa ggactttacc acatcgttaa ccttgaagcg
    42301 actgacgcag cagctcttaa cgagtttgac cgtctttcaa aaatcaatgg tgacattctt
    42361 cgtcacatga tcgttaaact tgacgcttaa ttccaactaa gagggtagtt tatgattaat
    42421 aatgtagtac tagttggtcg tatgaccaag gatgcagaac ttcgttacac accaagtcaa
    42481 gtagctgtgg ctaccttcac acttgctgtt aaccgtacct ttaaaagcca aaatggtgaa
    42541 cgcgaggcag atttcattaa ctgtgtgatc tggcgtcaac cggctgaaaa tttagcgaac
    42601 tgggctaaaa aaggtgcctt gatcggagtt acgggtcgta ttcagacacg taactacgaa
    42661 aaccaacaag gacaacgtgt ctatgtaaca gaagttgttg cagataattt ccaaatgttg
    42721 gaaagtcgtg ctacacgtga aggtggctca actggctcat ttaatggtgg ttttaacaat
    42781 aacacttcat catcaaacag ttattcagcg cctgcacaac aaacgcctaa ctttggaaga
    42841 gatgatagcc catttgggaa ctcaaacccg atggatatct cagatgacga tcttccattc
    42901 tagtcagaat ggattgaacg aatacgaaat tatttgagtt cgggctaaaa atttagaact
    42961 tagaatttag atcaactccc taggaaatca agatttcttg ccagttttct aaaattcagt
    43021 cgttttttaa gagcccttaa catcataatt tataaaggag aaaatacatg gctcaacaac
    43081 gtcgtggcgg attcaaacgc cgtaaaaaag ttgacttcat cgcagctaac aaaattgaat
    43141 atgttgatta caaagatact gagcttctta gccgtttcgt ttcagaacgt ggaaaaattc
    43201 ttcctcgtcg tgtaacagga acttcagcta aaaaccaacg taaagtaaca acagcaatca
    43261 aacgtgctcg cgttatggct cttatgcctt acgtaaacga agactaataa acaaacagtc
    43321 catttcggac tgttttttag ttgactagga ctagtctagg cgtataggtg agttttttct
    43381 aaaagagaga atgatagtaa acgaaaatcc ttgcgtagac agcaaggatg aaatgattgt
    43441 tatttgttaa caggtgacat agtgttttga atgttgtatt tgcgttgtag gtaatagcgt
    43501 aaagcaaggg aaacaccacc aataatgagc aaggcaagag gaggcaactg tgggttaaga
    43561 gaggttggta aaaaggcagt tgcagagtac aaggcaatcc aaatcaacat ggctaatgat
    43621 aaggctgcga tgattttgaa ccaacttgga cgaaggctct tatcttttcc gagatgacgg
    43681 taaataaagt aataagtagc gtacatggat gctcctccac caaaaccaag tgccagtaag
    43741 gaaatcaatc ctgtaactgt agcgtttgtg ttgaagaagg tcatgatgcc atttaaaagg
    43801 gcaacaattc cgatgaatag caaagaggta tctagccaca tcaaccaagg attggtgttt
    43861 ttgtcagttt ctgctgctct ttgactaggg tcttggctaa aagaagctgc ccaagcagtc
    43921 ggagtgccta atagatttcg agcggtgaca ccttttttct ggttttctag aatagctgga
    43981 atggcttctt cgagaatcag cttaatgtct tcatcagact tgccgtcttg gattaatttg
    44041 ttcgtagcgg tgtggataaa ttcttgattt tttttggtaa gttcttgtaa ttccatggga
    44101 atcccttctt tatatgggtt agttaaagta agtcaatggt attagctagt tgtaatgaaa
    44161 ctttggagct agccgtttga cacagagttt tgtcaggtct taaccgcatt ctgcagcttg
    44221 ctccactcta gaaccatttt tttctaataa agtaaatcac aacaaaggaa ctaagtagca
    44281 tagcaatcaa ggtaatatac caaaaagcat gttctaggcc atttagtggt aaccagttgt
    44341 tttggaaatt cataccatag gcggagaaaa tcacagttgg tatatctaaa gccatggtca
    44401 tcaaggccag tgttttcata atggtgttct ggttattgtt gataatggaa gcagtggttt
    44461 cggtcatggc attcaagaca ttttcataaa tgccagccat ctcaatcgcc tgttgggttt
    44521 caatcaaggt atcttctagc aaatcctcgt cctcaatgta tttcttgaga gagcttgttg
    44581 agctggataa tttcttgacg atgcgttcgt tgaatttcaa ggaagccttt aagtagacaa
    44641 tggatttttc aagttccatc atgtcgataa gttcttcatt tcgagtagct gcttcaagct
    44701 gagcttccaa acgttcgctt tggcgatcaa tggtcctcaa ggcagtcaga aagagctcgg
    44761 cgttgcgata tagaatctga aaaacaaaac gtgtcttcat gaaggtatag aaatttttga
    44821 cccggcggtt gtgaaaatga tcgaaaaggg tcatgtcatg cagacaagtt gtgataacag
    44881 cattttccgt tacaataatg cctaaaggca tagtaatata gtaactttta ttgttacgtt
    44941 cttcgtatat cggaacgtct acgataatta gggtataatc atcttctacg gcaatacgtg
    45001 aggtttcttc cacgtccaaa ggcgcgcgca agtcagaaat atcaatgtta aattgatcgg
    45061 cgatcttcat agactcttct tgggaagggt taaccagttt aatccaagct cctggctcga
    45121 atgtttctat ttctttgaat tcaattgccg atgaaagaaa catttgtttc atgacaagcc
    45181 ctcctttttg atgattgact ggtagagatt gacatcaaac cttgataata aagccttctc
    45241 aaggattttc tgaaaaattc tcaatactta tctattatac caaaattcgc aaagtttggg
    45301 gcaataggtt atcagaaatt tttgttataa tataagaaag ctcgatgagg agggtgcctt
    45361 taggcacatt caagatgcaa aataaaataa taattcatgg ggcaagagcc cacaatttaa
    45421 aaaatattga cgtggaaatt ccacgagaca aattagttgt cgtgacaggg ttatcagggt
    45481 caggaaaatc tagtctagcc tttgatacta tttatgcgga agggcaacgt cgttacgtag
    45541 aaagtttatc agcttatgct agacagttct tgggtaatat ggaaaaacca gatgtggatt
    45601 ccattgacgg tcttagccct gctatttcca ttgatcaaaa aactaccagt aagaaccccc
    45661 gctcaacggt tggtacggtt acggaaatca atgattattt acgtttacta tatgcgcgtg
    45721 tgggcacacc ttactgtatt aatgggcatg gggccattac agcatcttct gcagaacaaa
    45781 ttgtagagca ggtcttagcc ctccctgaac ggacacgcat gcagatttta gcgcctattg
    45841 ttcgccggaa aaaaggtcaa cacaaaacca tttttgagaa aattcaaaaa gatggttatg
    45901 tccgtgtgcg ggttgatggg gatatttttg acgtgacaga agtgccggag ctgtcaaaaa
    45961 gtaagatgca caacatcgag gtggttattg atcgtctggt taataaggat ggtattcgta
    46021 gccgtttatt tgattcggtt gaagcagctt taaggctggg agatggctac cttatgattg
    46081 acactatgga tggcaatgaa ctgctctttt ctgagcatta ttcctgtcct gtctgtgggt
    46141 ttacggttcc tgaattagaa ccaagactct tctcttttaa tgcgccgttc ggctcttgtc
    46201 ccacctgtga tgggctaggc attaagttgg aagtggattt ggacttggtt gttcctgacc
    46261 caagtaagtc tttgaaagag ggagctttgg cgccttggaa tcctatttcc tccaattatt
    46321 acccaaccat gcttgagcaa gctatggcaa gttttggggt ggatatggat acaccttttg
    46381 aggccttgac tgaggaagaa agggatttag tgctttatgg ttcaggtgat agagaatttc
    46441 attttcacta tgtgaatgat tttggtggtg agcgtaacat tgacattcct tttgaaggtg
    46501 ttgtgactaa tgttaatcgc cgttatcacg aaactaatag tgattatacg cgcaatgtga
    46561 tgcgtggcta catgaatgaa ttgacttgtg cgacttgtca tggttaccgt ttgaatgacc
    46621 aagccttgtg tgtgcatgtg ggtggcgaag aaggacctca tattggtcaa atttcagaat
    46681 tatcgattgc cgaccacttg cagttgttgg aagaactgga actcacagaa aatgaaagta
    46741 ccattgctaa accgattgtc aaagaaattc atgaccgcct gaccttctta aataatgtgg
    46801 gactgaatta tctgacctta tcacgtgctg ctgggacttt atcaggtggg gaaagtcaac
    46861 gaatcaggtt agcgacacaa attggttcta acttatcagg ggtgctctat atcttggatg
    46921 agccttctat tggattgcac caaagagaca atgaccgttt gatcgaaagc ctgaaaaaaa
    46981 tgcgtgattt gggtaatacc ttaattgtgg tagaacacga tgaagacacc atgatgcagg
    47041 cagactggtt gattgatgtg gggcctgggg caggtgagtt cggtggagaa attattgcct
    47101 ctggaacgcc gaaacaagtg gctaagaata aaaaatccat cacgggtcaa tatttgtctg
    47161 gtaaaaaatt cattccagtg ccattagagc gtcgttctgg taatggccga ttcattgaaa
    47221 taaaaggagc agcgcagaat aatcttcaaa gcctcgacgt gagattccca ctgggtaaat
    47281 ttattgcggt cacaggggta tcaggctcag ggaaatcaac cttggttaat agtattttga
    47341 aaaaggctgt cgcccaaaaa ttaaaccgta atgctgataa gcctggtaaa tatcactcta
    47401 tttctggtat tgaacatatt gaacgcttga ttgacattga ccaaagtccg attggaagga
    47461 cgccacggtc aaatccagcc acctatacgg gtgtctttga tgatattcga gacttgtttg
    47521 cccaaaccaa cgaagctaag attcgtggtt acaaaaaagg ccgtttctct tttaatgtca
    47581 aaggtgggcg ttgtgaggct tgttcaggtg atgggattat caaaatcgaa atgcactttt
    47641 tgccagatgt ttatgtgcct tgtgaggttt gccacggcag acggtataat tctgagacgc
    47701 ttgaggtgca ttataaagaa aaaaatattg ctgaagtgct tgacatgact gtggatgatg
    47761 ccttggtatt tttctctgct attcctaaaa tcgctcgaaa aattcaaacg attaaggatg
    47821 ttggacttgg ttatgtgacc ttaggtcaac cagctactac tctatctgga ggagaagcgc
    47881 agcggatgaa attagctagt gaattgcaca aacgctcgac aggtaagagc ttgtatatcc
    47941 tagatgagcc aacgactggt ttacacacag atgatattgc aaggctatta aaagttttgg
    48001 aacgctttgt agacgatggt aatacggttc ttgtgattga gcataatttg gacgttatca
    48061 aatctgctga ccatattatt gacttaggac cagaaggtgg tgtcggaggt ggtcagattg
    48121 ttgccacggg gacaccagaa gaggtagctc aagttaaaga aagctatact ggtcattatt
    48181 tgaaagtaaa actacaacaa taggattagg agttcgtttg agctcctttt aatcttttaa
    48241 atgctctcaa atcatggtaa acttaaagta gttttttcat gctacaatat tctcaaaagt
    48301 taccaaagga gttcgcgatg tcaggatttt tagagcaacg attaggtcac tgcctaaggc
    48361 agatggcaga gaaggggcta gaggctcttc tggtcaccca tttaaccaat agttattact
    48421 tgacaggttt ttctggaact gcagcaactg ttttgataac ggccaaacgt cgtgttttga
    48481 tcacagattc acgttatacc ttgcttgcta aagctagtgt tgagggattt gatattatcg
    48541 aaagccgcac gcccctgaat gttgtggcag aattgttagg ggctgatcaa atagattgcc
    48601 ttggttttga ggaccaggta tcgttttctt tttatcaggc catgcaagca gaactgtcag
    48661 gaataacctt gcttgctcag tcaggctttg tggagcattt acgtcttatt aaggacgtct
    48721 ctgaaattga gaccattgct aaagcgtgct cgatctcaga caaagcattt gaagatgctc
    48781 ttgattttat taaaccaggg acaaccactg aacgtgacct ggctaatttt ttagattttc
    48841 gcatgcgtca gtatggtgcc agcggcacat catttgatat cattgcagct tcaggctatc
    48901 gctctgccat gcctcatgga cgcgccagtg acaaggttat ccagaataaa gagagcttga
    48961 ccatggactt tgggtgttac tacaatcact atgttagtga tatgacgagg accattcaca
    49021 ttggccaagt tactgatgaa gaacgtgaga tttatgctct tgttcttgct gctaataagg
    49081 ctctaattgc taaagctagc gctggcatga cttatagtga ctttgacggt attccgcgcc
    49141 aacttatcac tgaggcgggt tatggcagtc acttcacaca tggcattggt catggtatcg
    49201 ggcttgacat ccatgagaat ccatttttgg ggaaatctga gcaacttctc caagctggaa
    49261 tggtggtcac agacgagcca ggtatctatt tggataacaa atatggtgtc cgtattgaag
    49321 atgacttggt tatcacaaaa actggttgtc aagtcttgac cttggcaccc aaagaattaa
    49381 ttgtattgta aaagaatggt tcaggaaagg attaggggag aagcaatgac aaatcgttta
    49441 tcatggcaag actattttat ggccaatgca gagctgattt ccaagcgctc tacctgtgat
    49501 cgcgcctttg tgggagctgt tttggtaaag gataaccgca ttattgccac aggttacaat
    49561 ggcggagttt ctgctacgga taactgcaac gaagcgggtc attatatgga agacggtcat
    49621 tgtattcgca ctgttcatgc tgaaatgaat gctttgattc aatgtgcgaa agaaggaatt
    49681 tcaacggacg gaactgaaat ttacgtgact cattttcctt gtattaactg cactaaggcg
    49741 cttttgcagg cggggattac aaagattacc tataaagcac attatcgtcc gcaccccttt
    49801 gccattgaac tgatggagaa aaaaggggtt gcctatgtgc aacatgatgt gcctcaaatt
    49861 gttttaggag gcgataagga acaatagaaa gtgtacctaa aaggacggtc ataaaagatt
    49921 tgagccaagg ccacttttgt ggtaaaatga agtgataaat attttagtaa gaggtaataa
    49981 taatgattga agcaagtaag cttaaagcag gtatgacatt tgaagcagaa ggaaaattaa
    50041 tccgtgtcct tgaagctagc caccacaaac caggtaaagg aaacactatc atgcgtatga
    50101 aactacgtga tgtgcgtaca ggttctactt ttgacacaac ttaccgccca gatgaaaaat
    50161 ttgagcaagc catcattgaa actgtcccag cacaatacct atacaaaatg gatgacactg
    50221 cttacttcat gaacactgat acttatgatc agtacgaaat tccagttgct aacgttgagc
    50281 aagaattgct ttacattctt gaaaactcag acgtgaaaat ccaattttat ggaagtgaag
    50341 tgattggggt aacggttcca acaactgttg aattgaccgt tgcggaaaca caaccatcta
    50401 ttaaaggagc gacagtgacg ggttcaggga aacctgcaac tcttgagaca ggacttgttg
    50461 ttaacgttcc agactttatc gaagctggcc aaaaactaat cattaacact gcagaaggta
    50521 cttacgtttc tcgtgcttaa tcctttgtca aaacagatta gtctaaaaaa gagaaaggaa
    50581 atgctatgac aactgaatat atcggtgaaa tcgtcatttc accacgagtg cttgaggtta
    50641 ttacggggat tgctacgaca caagttgagg gcgtccactc actccataac aagaaaatgg
    50701 cagatagctt taacaaagca agtcttggta aaggggttta tctccagaca gaagaagatg
    50761 gaagtgttac agcagatatt tatgtttact tgcaatatgg agttaaggtc ccgactgtat
    50821 ctatgaatat tcaaaaaaca gtcaaatctg ctgtgtacga tatggcagaa gtgcctattt
    50881 ctgcagttaa tatccatgtt gaaggtattg ttgctgaaaa gacaccaaaa ccagatttga
    50941 agtcactttt tgatgaggat ttcttggatg actaacagct ttcaaaattc aagaagagat
    51001 ttgcgtgaac gtgcctttca ggctttattt aacatagaga tgggagctga gttattggca
    51061 gcttctcagt ttgcctatgg ttatgataaa gtaacagggg aggacgctca agtattggag
    51121 ctgccgattt ttttattaag tcttgtgacg ggtgtcaata atcataaaga agagttggat
    51181 aacttgatat caactcattt gaaaaaaggt tggtcgttag aacgcttgac actaacagac
    51241 aaaacgttat tacgactagg tctttttgaa atcaagtatt ttgacgaaac accagaccgt
    51301 gttgcactaa acgaaatcat tgaagtagct aaaaaatatt ctgatgaaac ctctgctaaa
    51361 tttattaatg gcttacttag ccaatatgtc tcggaagctc cttcagcaaa taaatcataa
    51421 taagtcggag caatcttagg attgtatccg attttttcaa tttatgtacg aatattaaaa
    51481 gacaaacaag catactctcg catctagaaa gagtatgctt gtttgtcttt tagagtaatt
    51541 agtgattggt tatgttttgt ttaaatactt gctcctggaa gtagcgtaat cggtaaaata
    51601 tagtctttac tggttttttc ttttttaatt tttttgatga gtatttcgac actcaattta
    51661 gcaatctcat caataggttg acgaatggtc gctaattgag gaacatattg ctggataaat
    51721 gtcgttccat cataacctat gactttcata tcctctggaa tagtaatgtg aagttgtttg
    51781 gctactttca taataaggat agcagttaaa tcatcagaaa cgaaaaggcc atcaggtttt
    51841 cgggttgcca aaatggattt aatttccatt tcgcgtctaa caggagatag gttatttggt
    51901 aatttgagga tttctgcact tcgtttgagc tggtagttaa accctagctg gcgcaaccct
    51961 gtgggcgaat cagaattgtc attacctgta atcatgacaa tgttttgaca accgtgtttt
    52021 tgcaaagttt gtgcggctaa tttaccacct tcaaaattat ctgaagaaat aaccgggata
    52081 tttggcgcta gattacggtc aaaagctaca ataggagctt cgacacgctc ataatcctca
    52141 attcccaaat tatgactgga agaaataatg ccgtccactt gattggccgc aagcatttct
    52201 aagtattcgc gttctttgac gggattatgt tcactattgc aaataatagt tttgtagccc
    52261 tgtttaaaca attcaatttc caaatgttca attaattcag cgtaaaagat attgctaatg
    52321 ttggggaaga taagcccaat gagttgggtt gatttacctt gcaaacttct agcgagattg
    52381 ttaggcttgt agcccaattc acgcatggcc ttattcacct tattcactgt tttttgggaa
    52441 aggtagcctt ttttgttgat tactcgcgaa acagttgttg gactgacacc cgccaaggct
    52501 gccacgtctg ttaattttgc gaccacttgc ctaatacctc atttcataat aatgtccaaa
    52561 agcttgtcct tctactactt ggatacctgt ttgtccttgg gttgggaaaa cacgactcgt
    52621 taggactttt tgcccttggt taataaagat ttcaagaatg gaattgtcca catagacatt
    52681 aagtgtaaca tggccttgtg ggatttggca agagcgcatc gtaccatagt cttgggcata
    52741 ttgaacccct gcccgacttc ggtcaatgct taactgtcct tttgttgtat ccaccttcaa
    52801 tcttaggcca ttcccttttt ggtcggcaaa taggagcagg tcaagctttt tttggcctgg
    52861 aatcgtcaat tccaactcat aacagttaga actgtctatt ttattatgaa ataattctgc
    52921 tggccctcga agattttgta gggctgaaac aggtgtttga tagagaattc cgtctttaat
    52981 ccttaattct ttcactaaac taagagctcc ttgatagtca taacgatctg tcggataatc
    53041 aatatctggt aacccaatcc aagacacggc tagaaccctg ccatctggac tactaaaggc
    53101 ttgagtggca taagcttcaa aaccaaagtc aagattttga agggcccttc cacccagcaa
    53161 ttggccagtt tctggattga agctttcaaa aattttatag gtattggggt agatattttg
    53221 ataatctaaa tcagctttag ccagtccttg tgggctgaaa atcaaaacag gcttgtcatc
    53281 gacaaacaca aggttggggc attcaatcat gtattccgta ccagaatcgt caaggtccaa
    53341 atcggctata aatcgccagt tgtccacatg attgtccaca gctttgtaaa gtttgatttt
    53401 tcctttgcca tctaaacctt gggcgccaat aatagcatag aattgacctt gataagaaaa
    53461 aagctgagga tcccgaaaat gttctgtaac atcatcgggc tgttcaatca aaacctgtgg
    53521 tattttggaa atatttcctt gtttatccat ccatgcgcca acctgtaatg gtgttctgac
    53581 ccaattggca tcgcgaacat taccagtgta aaagaggaag agcttgtcat caatagcata
    53641 tgcagaacct gagtaagccc catgactatc gtgagcgtgg tctggcagaa ggcggctcct
    53701 tgtttccgta aaatggacga ggtctgtgga tgtcatgtgt acccattgtt tcagaccatg
    53761 cgcagcgcca taaggccagt tttgataaaa aagatggtag cgaccgttga aataagaaaa
    53821 cccattgggg tcattgagta atcctgtctt aggttcgaca tgaaattggc tgtgccatgg
    53881 ggattgggcc attttttcag taatagcttg gtagtctttt gagctccact ctttgtaagg
    53941 gcggtagcga atagcttgtg gtagatccat caaaatctcc ttgttttata gtcgtcttca
    54001 agaatatact aaacgttttc tgtttaaaaa tcaagaattt aaagcatata aaataaaaat
    54061 atgttaaacg cttgacataa aaaatattag tgataaaatg atagtcaaga agtgaagcgg
    54121 attcactagc gttggtcatg cacattctta gccacaaagc tggcagaatg gaggagggac
    54181 taacaccaaa tgaaaaagga gacttttagg catggataat cgtcagattg cagctgaagt
    54241 gattgaggct ttaggtggtc gagaaaatgt gagaagtgtt gcccactgtg caactcgcct
    54301 tcgcgtgatg gtttatgatg aaggaaagat tgataaggaa aaagcagaag ctattgacaa
    54361 ggttaaagga gctttcttta attctggtca atatcaaatg atttttggaa ctggtaccgt
    54421 taataacatt tatgacgaag tcgttgctct tggtttacca acatcatcaa ccagtgagca
    54481 aaaggcagaa gcaggcaaac aaggcaatat cttccaacgg gcgattcgta cgtttggaga
    54541 tgtctttgtt cccattattc cagctattgt agcaacgggt ctctttatgg gggttcgtgg
    54601 tttggtgacc cagccagcta ttatggattt atttggggtg catgagtacg gggaaaattt
    54661 tctcatgtac actcgtattc taacggatac agcctttgtc tacttgccag ctttggtggc
    54721 ttggtcagcc tttagggtct ttgggggtaa tcctattatc ggtattgttt taggattgat
    54781 gctggtttcc aatgagttgc ctaatgcttg ggtagttgcc tctggtggag atgttaagcc
    54841 gctaaccttc tttggatttg ttcctgttgt tggttatcaa ggtaccgttt tacccgcctt
    54901 ctttgttggt ctggtaggag ctaagttgga gaaatggttg cacaaaaagg ttccagaagc
    54961 tttagactta ttggtcacac cgtttttaac gtttgctatt atgagtatct tgggactatt
    55021 tgtgattgga ccagtcttcc attctcttga aaaccttgtt ctggctggga cacaggccgt
    55081 cttgcatttg ccgtttggca ttgctggtct tattgttggt ggtatccaac agttgatcgt
    55141 cgttactggt attcaccata tctttaactt cctagaagcg cagctaattg ccaataccgg
    55201 aaaagatcct ttcaatgctt acctaacagc agcaacagct gctcaagctg gagctacctt
    55261 agctgttgct gttaaaacca aatcaacaaa actaaaaggt ctggcctttc catcaacctt
    55321 gtcagctctt ttagggatta ctgaaccagc tatttttggg gtcaacctcc gttatccaaa
    55381 agtctttgtt tcaggtctta ttggtggtgc cttaggtggt tgggtcgctg ggctctttgg
    55441 cattgcagga actggttttg ggattacagt cttaccagga acgctccttt acttgaatgg
    55501 ccaattatta caataccttg tgactatgct tgtcggtctt ggggtagcct ttgcaattgc
    55561 ttatacttgg ggttatcaag atagagaaac ccttccgtta ccagctgtcg aagttgatca
    55621 aacggctgat cagccagcct tagcagagga aactttatat agtcctttga atggaacagt
    55681 tgtagattta gcagctgttt cagaccctgt tttttcatca ggtgctatgg gtcaaggctt
    55741 agcaattaag ccagaagata ataccctata ctcaccagtt gatggtaaag ttgaaattgt
    55801 ctttgaaaca ggtcatgcct atgctataac gtcaagtcaa ggagcagaag tgttacttca
    55861 tattggtatt gataccgtgt cgatggcagg agatggcttt gaatctcttg tagcagtagg
    55921 tcaggcggtt aaaaaaggtg atcttcttgg acactttgat cctagcaaga ttgcagaagc
    55981 tggactagat gacaccacca tgatgattgt gaccaatagc actgactatc aaagcgtgga
    56041 cattcttgct caaggacatg ttttgattgg tgatcaagtg gcacttatca aataaggaca
    56101 aaagagctaa ctaagcagct cttttgtcct gccatgaatg gcaggttggc aaaaaaatga
    56161 gaaaagccta aaaaccttaa atttgtgtta ttttacctat actttgtacc ttgttttttt
    56221 taataaagtg ttgttatact taaggcgaac tataggaatg cgcttacata gatggtatat
    56281 caactgggaa gccatgactt agtaccaaaa ataaggagtg tccaaatgga taaacatttg
    56341 ttggtaaaaa gaacactagg gtgtgtttgt gctgcaacgt tgatgggagc tgccttagcg
    56401 acccaccatg attcactcaa tactgtaaaa gcggaggaga agactgttca ggttcagaaa
    56461 gaattatctt ctatcgatag cttgcattat ctgtcagaga atagcaaaaa agaatttaaa
    56521 gaggagcttt caaaagaaaa agtaccagaa aaggtcaaag agatattagc aaaagctcag
    56581 caggcagata aacaagctca agaacttacc aaaatgaaaa ttcctgagaa aataccgatg
    56641 aaaccgttac atggtcctct ctacggtggt tactttagaa cttggcatga caaaacatca
    56701 gatccaacag aaaaagacaa agttaactcg atgggagagc ttcctaaaga agtagatcta
    56761 gcctttattt tccacgattg gacaaaagat tatagccttt tttggaaaga attggccacc
    56821 aaacatgtgc caaagttaaa caagcaaggg acacgtgtca ttcgtaccat tccatggcgt
    56881 ttcctagctg ggggtgataa cagtggtatt gcagaagata ccagtaaata cccaaataca
    56941 ccagagggaa ataaagcttt agccaaagct attgttgatg aatatgttta taaatacaac
    57001 cttgatggct tagatgtgga tgttgaacat gatagtattc caaaagtgaa tgggaaagct
    57061 agtgacgaaa acctcaagcg atctattgat gtttttgaag aaattgggaa attaattgga
    57121 ccaaaaggtg ttgataaatc gcgtctgttt attatggata gcacttacat ggctgataaa
    57181 aacccattga ttgagcgagg agctccttat attgatttgt tattggtaca agtctatggc
    57241 gcaagaggag aacaaggtga gtttcaaaac gataccaagt tagttaccga gactcctgaa
    57301 gaacgatggc aaggttatag caagtatatt cgtcctgaac aatacatgat tggtttttct
    57361 ttctatgagg aaagagcagg cagcggcaat ctttggtatg atattaattc tcgaaaggac
    57421 gatgacaaag caaatggaat taacactgac ataactggaa cgcgtgccga acggtatgca
    57481 aggtggcaac ctaagacagg tggggttaag ggaggtatct tctcctacgc tattgaccgt
    57541 gatggtgtag ctcatcaacc caaacaaata gctgaaaaag ataaacagaa tgtaaaaaat
    57601 aatcagcctc agattccaga gattactgat aacattttcc actcagatta tagtgtctct
    57661 aaagcattaa agacagttat gctaaaagat aagtcgtatg atctgattga tgagaaagat
    57721 ttcccagata aggctttgcg agaagctgtg atggcgcagg ttggaaccag aaaaggtgat
    57781 ttggaacgtt tcaatggcac attgcgattg gataatccag cgattcaaag tttagaaggt
    57841 ttaaataaat ttaaaaaatt agctcaatta gacttgattg gcttatctcg cattacaaag
    57901 cttgaccaat ctgttttacc cgctaatatg aagccaggca aagatacctt ggaaacagtt
    57961 cttgaaacct ataaaaaaga taacaaagaa gaacctgcta ctatcccacc agtatctttg
    58021 aaggtttctg gtttaactgg tctgaaagaa ttagatttgt caggttttga ccgtgaaacc
    58081 ttggctggtc ttgatgccgc tactctaacg tctttagaaa aagttgatat ttctggcaac
    58141 aaacttgatt tggctccagg aacagaaaat cgacaaattt ttgatactat gctatcaact
    58201 atcagcaatc atgttggaag caatgaacaa acagtgaaat ttgacaagca aaaaccaact
    58261 gggcattacc cagataccta tgggaaaact agtctgcgct taccagtggc agagggaaac
    58321 attgatttgc aaagccagct tttgtttggg actgtgacga atcaaggaac cctaatcaat
    58381 agcgaagcag actataaggc ttaccaaaat cataaaattg ctggacgtag ctttgttgat
    58441 tcaaactatc attacaataa ctttaaagtt tcttatgaga actataccgt taaagtaact
    58501 gattccacat tgggaaccac tactgacaaa acgctagcaa ctgataaaga agagacctat
    58561 aaggttgact tctttagccc agcagataag acaaaagctg ttcatactgc taaagtgatt
    58621 gttggtgacg aaaaaaccat gatggttaat ttggcagaag gcgcaacagt tattggagga
    58681 agtgctgata gtcaagcagc tttaaaagcc tttgatgggg taatagagta caatccgata
    58741 tctactcaga atagagcttc gattatcttt gaaatgaaag accctagttt agcaaaatat
    58801 tggcgccttt tcaatgatag cagtaaaggc gaagacgact atatcaaaga agcaaaactt
    58861 gaagtcttta caggccagct gaatgctgaa gcagatgtga aaacgagctt ggaaaaatca
    58921 gatgattggc aaactgtttc aacctattca ggacaagaac aggtatttag ccatgcactg
    58981 gataatatta gtgctaagta ctggagagta accgtagata ctaagggagg aaattatagt
    59041 tggccatcac tccctgaact ccaaatttta ggttatccgt tacctaacgc cgacactatc
    59101 atgaaaacag taactactgc taaagagttg tctcaacaaa aagataagtt ttctcaaaag
    59161 atacttgatg agttaaaaat aaaagagatg gctttagaaa cttctttgaa cagtaagatt
    59221 tttgatgtaa ctgctattga tgctaatgct ggagttttga aagattgtat tgagaaaagg
    59281 cagctgctaa aaaaataaac aaagtaactc tcttagatag caacattcag attaaattaa
    59341 caaaatgtga ctatgataaa ggtttgctgg aattgattaa ccaaaagact aaaaatctga
    59401 gatgaatagt cccagatttt tagtctttta taggttttga tgacataaag ctaaataatc
    59461 gttagactac cagaaagtgg cgcttgtccg tgagacatgg ctgtcttgat aagagcctgt
    59521 gtcatcataa agataaaaaa gaacaagaaa aaggagaaaa catgggaaaa ttatatggaa
    59581 gtattgaagc tggtgggaca aagtttgtct gtgccgtggg tgatgaggag tttacagtgg
    59641 tggataaaac acaatttccg accaccacac cagaagaaac catcgcgcaa accatcgcat
    59701 attttaaaac ctttgaggcc gatttggctg gaatggcgat tggttctttt ggaccaattg
    59761 atattgatcc gtcgtcagag acttacggtt atatcacaac cactcctaag tcaggctggg
    59821 ctaatgtgga tttgttagga caactttcgg ctgcttttaa gattcctttt gatgtgacaa
    59881 cagatgttaa tagctctgct tatggtgagg tgcttgctcg tcctggtgtg gaaagtttgg
    59941 tctattacac cataggtact ggtattgggg cgggagctat tcaacatggc cactttattg
    60001 ggggattagg tcatacagaa gcgggtcata cctatgtcat gctccatcct gatgatatgg
    60061 ccaagggatt tttaggtgtt tgcccttttc ataaagggtg tctggaaggg atggcagcag
    60121 gtccaagtat tgaggccaga acgggagtga gaggtgaacg gcttgatcag gaagctgatg
    60181 tttgggacat tcaagctttc tacattgccc aagcagcgct gcaagcaact atgctttacc
    60241 gtcctcaagt gattgttttt ggcggaggtg tcatggcgca agaacatatg gtgttgcgcg
    60301 tgcatgataa attcactacc cttttaagcg gttatttgcc agtccctgat ttgacagact
    60361 acattgttac tccagctgtt gctgataatg gctccgctac tctgggaaat tttgctttgg
    60421 ccaagttggc tgcacaagga aaatagggtc tgtttttgcc tgcttgtcta gtaaaagaaa
    60481 gcgcagtcag ctagaacatg ctataataaa cagagattaa catcagaagc gaggaatatt
    60541 atgtcagaac cattatttct aaaatcaacc atgcacgaca gaatttgggg tggcaccaag
    60601 ttgagagatg tctttgctta caacatccca agtgacacca caggtgagta ttgggctatt
    60661 tctgctcatc ctaatggtgt ttcgacagtt actaatggac gttatcaagg acaaccttta
    60721 aatacattat atgcgcaaga gccagccttg tttgggaatc caaaggaaga agtttttcca
    60781 ctgttaacta agattttaga tgctaatgac tggctaagtg tccaagttca tcctgatgat
    60841 gcttatggac gtgaacatga aggagaatta ggcaagacag aatgctggta tattatttct
    60901 gccgaagagg gttctgaaat tgtatacggc catcaggcca agtccaaaga agaccttcgt
    60961 gccatgattg aagcaggtgc ttgggatgat ttgctgactc gtgtcccagt caaagcaggc
    61021 gattttttct atgttccaag tggcaccatg catgcgatcg gcaagggaat tcttatttta
    61081 gaaacccagc agtcatctga taccacttat cgggtttatg attttgaccg taaggacgtt
    61141 aatggtaatc ttcgtgacct tcatattgaa aagtctattg atgtcttaac gattggtaag
    61201 ccagaaaata gcgtgccagc cactatggtt ttggataata tggtagcaac aactttagtc
    61261 tcaacgccat ttttcactgt ttacaaatgg gtgactagtc aaatggttga catgaaacaa
    61321 gctgcgcctt atcttttagt gagtgtttta aaaggtcaag gaaaactcta tgtggaccag
    61381 aaggcttatg agctagaaaa aggcatgcac tttatcttgc ctaacgatgt taaatcgtgg
    61441 tcatttgatg gtcaattaga aatgattgtg agtcacccca atcaactcgt ttaataccat
    61501 ggtatcaata tgagaaaaaa ggataaaatt atgactctct gtttctctga taacttt
//
LOCUS       DAUGOH010000007        57342 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUGOH010000007 DAUGOH010000000
VERSION     DAUGOH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57342
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.007"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            134..295
                     /gene="sagA"
                     /locus_tag="VH957_000451"
     CDS             134..295
                     /gene="sagA"
                     /locus_tag="VH957_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEQ8558393.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            517..1467
                     /gene="sagB"
                     /locus_tag="VH957_000452"
     CDS             517..1467
                     /gene="sagB"
                     /locus_tag="VH957_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEQ8558394.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1464..2522
                     /locus_tag="VH957_000453"
     CDS             1464..2522
                     /locus_tag="VH957_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEQ8558395.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAINTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNDPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSDALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHACTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2542..3900
                     /locus_tag="VH957_000454"
     CDS             2542..3900
                     /locus_tag="VH957_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEQ8558396.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3875..4546
                     /locus_tag="VH957_000455"
     CDS             3875..4546
                     /locus_tag="VH957_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8558397.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELIFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4543..5226
                     /locus_tag="VH957_000456"
     CDS             4543..5226
                     /locus_tag="VH957_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEQ8558398.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLMALSYQDFLDV
                     LLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5249..6172
                     /locus_tag="VH957_000457"
     CDS             5249..6172
                     /locus_tag="VH957_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558399.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6181..7308
                     /locus_tag="VH957_000458"
     CDS             6181..7308
                     /locus_tag="VH957_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558400.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            7305..8423
                     /locus_tag="VH957_000459"
     CDS             7305..8423
                     /locus_tag="VH957_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558401.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALIIFSSLLLKPTRL"
     gene            8995..11727
                     /locus_tag="VH957_000460"
     CDS             8995..11727
                     /locus_tag="VH957_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEQ8558402.1"
                     /translation="MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTSLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVIKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGCVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      11892..12007
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            12005..12505
                     /locus_tag="VH957_000461"
     CDS             12005..12505
                     /locus_tag="VH957_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEQ8558403.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12699..14657
                     /gene="ligA"
                     /locus_tag="VH957_000462"
     CDS             12699..14657
                     /gene="ligA"
                     /locus_tag="VH957_000462"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEQ8558404.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTAVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWNFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRKL"
     gene            14671..15693
                     /locus_tag="VH957_000463"
     CDS             14671..15693
                     /locus_tag="VH957_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8558405.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            16085..16282
                     /locus_tag="VH957_000464"
     CDS             16085..16282
                     /locus_tag="VH957_000464"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEQ8558406.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16317..17033
                     /gene="atpB"
                     /locus_tag="VH957_000465"
     CDS             16317..17033
                     /gene="atpB"
                     /locus_tag="VH957_000465"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEQ8558407.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17051..17545
                     /gene="atpF"
                     /locus_tag="VH957_000466"
     CDS             17051..17545
                     /gene="atpF"
                     /locus_tag="VH957_000466"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEQ8558408.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17545..18081
                     /locus_tag="VH957_000467"
     CDS             17545..18081
                     /locus_tag="VH957_000467"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEQ8558409.1"
                     /translation="MTKKEQAIIEQYAKSLVEVASEHHSLDTLQADVLAILETFETTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKNRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18097..19605
                     /locus_tag="VH957_000468"
     CDS             18097..19605
                     /locus_tag="VH957_000468"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEQ8558410.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19621..20496
                     /locus_tag="VH957_000469"
     CDS             19621..20496
                     /locus_tag="VH957_000469"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEQ8558411.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20658..22064
                     /gene="atpD"
                     /locus_tag="VH957_000470"
     CDS             20658..22064
                     /gene="atpD"
                     /locus_tag="VH957_000470"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEQ8558412.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22077..22493
                     /locus_tag="VH957_000471"
     CDS             22077..22493
                     /locus_tag="VH957_000471"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEQ8558413.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22759..23016
                     /locus_tag="VH957_000472"
     CDS             22759..23016
                     /locus_tag="VH957_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEQ8558414.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23081..24352
                     /gene="murA"
                     /locus_tag="VH957_000473"
     CDS             23081..24352
                     /gene="murA"
                     /locus_tag="VH957_000473"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8558415.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24356..24544
                     /locus_tag="VH957_000474"
     CDS             24356..24544
                     /locus_tag="VH957_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8558416.1"
                     /translation="MTNGLKYVLEQMLLLFIIAALACLFLAIGLMIGYSFMGDGQSPW
                     HILSMDKWAELVNKFTGK"
     gene            24580..25119
                     /locus_tag="VH957_000475"
     CDS             24580..25119
                     /locus_tag="VH957_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEQ8558417.1"
                     /translation="MLTRKKRKRVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRTFK
                     PAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKP
                     YSTGQNYYEGLVCRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVP
                     NVQAGLTVDYRTGQIAINL"
     gene            25402..26445
                     /gene="pheS"
                     /locus_tag="VH957_000476"
     CDS             25402..26445
                     /gene="pheS"
                     /locus_tag="VH957_000476"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8558418.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGENISMGDLKGTLEMIIKKMFGDERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            26655..29060
                     /locus_tag="VH957_000477"
     CDS             26655..29060
                     /locus_tag="VH957_000477"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEQ8558419.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPADGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEVGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKENLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLASMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELNMAALEAALSSDQTFVEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTKIKLFDVYEGVTIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKSLTEQVGA
                     EVR"
     gene            29171..29548
                     /locus_tag="VH957_000478"
     CDS             29171..29548
                     /locus_tag="VH957_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEQ8558420.1"
                     /translation="MYQTKITGNRLYRTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            29541..29927
                     /locus_tag="VH957_000479"
     CDS             29541..29927
                     /locus_tag="VH957_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEQ8558421.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            30000..31076
                     /locus_tag="VH957_000480"
     CDS             30000..31076
                     /locus_tag="VH957_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558422.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GIGNITIAQAVLLQTFLLSALGSGLGLLGTWLTSLVLPEAVPFQSNWLVYLAILVSMV
                     CFALLGTLFSVFSIVRIDPLKAIG"
     gene            31086..31754
                     /locus_tag="VH957_000481"
     CDS             31086..31754
                     /locus_tag="VH957_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558423.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYQMQDGEL
                     RQER"
     gene            complement(31858..32775)
                     /locus_tag="VH957_000482"
     CDS             complement(31858..32775)
                     /locus_tag="VH957_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEQ8558424.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQAGYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRAVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            32926..36141
                     /gene="rexB"
                     /locus_tag="VH957_000483"
     CDS             32926..36141
                     /gene="rexB"
                     /locus_tag="VH957_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEQ8558425.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            36102..39770
                     /gene="addA"
                     /locus_tag="VH957_000484"
     CDS             36102..39770
                     /gene="addA"
                     /locus_tag="VH957_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEQ8558426.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERYSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPAFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGNVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QIPQLLNADDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            39909..40721
                     /locus_tag="VH957_000485"
     CDS             39909..40721
                     /locus_tag="VH957_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8558427.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAVQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLETPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            40862..41038
                     /locus_tag="VH957_000486"
     CDS             40862..41038
                     /locus_tag="VH957_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEQ8558428.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(41166..41528)
                     /gene="mscL"
                     /locus_tag="VH957_000487"
     CDS             complement(41166..41528)
                     /gene="mscL"
                     /locus_tag="VH957_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEQ8558429.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAV
                     APTQEELLTEIRDLLAQK"
     gene            41658..43472
                     /gene="dnaG"
                     /locus_tag="VH957_000488"
     CDS             41658..43472
                     /gene="dnaG"
                     /locus_tag="VH957_000488"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8558430.1"
                     /translation="MGFLWGGDDLAIDKEMIFQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNISSSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADTEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPMPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     ELLYQRLKQQGHITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            43481..44590
                     /gene="rpoD"
                     /locus_tag="VH957_000489"
     CDS             43481..44590
                     /gene="rpoD"
                     /locus_tag="VH957_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEQ8558431.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            44826..45164
                     /locus_tag="VH957_000490"
     CDS             44826..45164
                     /locus_tag="VH957_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEQ8558432.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            45302..46156
                     /gene="rfbD"
                     /locus_tag="VH957_000491"
     CDS             45302..46156
                     /gene="rfbD"
                     /locus_tag="VH957_000491"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEQ8558433.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            46275..47429
                     /locus_tag="VH957_000492"
     CDS             46275..47429
                     /locus_tag="VH957_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEQ8558434.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTK
                     QKGQLAELINQVDAGFDSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            47419..48351
                     /locus_tag="VH957_000493"
     CDS             47419..48351
                     /locus_tag="VH957_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8558435.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLNPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            48354..49157
                     /locus_tag="VH957_000494"
     CDS             48354..49157
                     /locus_tag="VH957_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558436.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            49157..50362
                     /locus_tag="VH957_000495"
     CDS             49157..50362
                     /locus_tag="VH957_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558437.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            50387..51394
                     /locus_tag="VH957_000496"
     CDS             50387..51394
                     /locus_tag="VH957_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8558438.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTIYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEVSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            51391..53136
                     /locus_tag="VH957_000497"
     CDS             51391..53136
                     /locus_tag="VH957_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEQ8558439.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMGPYFENFEEKEAVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKTESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETNDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            53133..55607
                     /locus_tag="VH957_000498"
     CDS             53133..55607
                     /locus_tag="VH957_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8558440.1"
                     /translation="MIKDTFLKTNWLNISHHITLLVFGFYFSFYSLAKELVSSTAQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLCYQGNTFS
                     VALILAVVPISDIHLLKLISSRFSELVRAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            55786..56481
                     /locus_tag="VH957_000499"
     CDS             55786..56481
                     /locus_tag="VH957_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8558441.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            56483..56824
                     /locus_tag="VH957_000500"
     CDS             56483..56824
                     /locus_tag="VH957_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEQ8558442.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            56817..>57342
                     /locus_tag="VH957_000501"
     CDS             56817..>57342
                     /locus_tag="VH957_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ8558443.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSSDSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCI"
BASE COUNT        18272 a         9571 c        11488 g        18011 t
ORIGIN      
        1 gatagttgtt gtgttacaac agtacaattg agctagcctt gtccttgttg tgttaacttt
       61 atttttaaaa taaggttaaa aataaacgac tcgcgttctt atcagttact tattagataa
      121 ggaggtaaac cttatgttaa aatttacttc aaatatttta gctactagtg tagctgaaac
      181 aactcaagtt gctcctggag gctgctgttg ctgctgtact acttgttgct tctcaattgc
      241 tactggaagt ggtaattctc aaggtggtag cggaagttat acgccaggta aataatctat
      301 ttagcatctc tatgtgatag tgatattaag gtaatgagtt tgctagcaac taagttatct
      361 ttggtaactt ctgattatag atgaatggca tagaggtgtt agaaaacatg agacaaaagt
      421 aatcttcttg atgctaacgt ctcaggtaat tagcaggtac tagatagtac ctgctaatta
      481 ctatatgttt agtaaaatga gataggaaag atagttatgt cattttttac aaaggaacaa
      541 caacctaaag agaattgtcc gccaataact gttgaaaaag caaggcaatt gtttgaattt
      601 aatacaaacc acttgtcctt atcggattac catcatcaaa cggtgctaaa aacgtcaaag
      661 cagctagttg ctcaacattt aatgcctaat gcaaccgata atcttagtca acattttttg
      721 atgaactata aagctaataa taattattta ggcttccaag ctagtattgt cgactttttt
      781 acagattctg ccgttgctaa tttttcaagt agttacgttt atgaaagtca ggaaaagata
      841 attcgtttac caaaacctac caagatatca actgctctgt cgacatgtat tataaaacga
      901 agaagtcatc gtcaattttc agatagacaa atgcctcttc aagatttatc aaacattctt
      961 tattatgcat gtggtgttag ttcacaagca tcaattagag atggagcatc agataagatt
     1021 acactcagaa actgtgcttc aggtggaggt ttatacccta ttcatttagt tttttatgct
     1081 agaaacatca gtaaattaat agatggtttc tatgaatacc taccctatca gcatgcacta
     1141 aggtgttatc ggcatagctc tgaggaaaac gttagagatt ttgcggaata cggtgctatt
     1201 aatgctgaaa attgtaatat tattattatt tatgtctacc attacatgaa aaatacacgt
     1261 aaatatggga atcaggcgac tgcctatgct tttattgaat caggagaaat agcccagaat
     1321 attcaattga ctgcaactgc cttaacttat ggaagtattg atattggtgg ttataataag
     1381 gaatatctcc aagaattatt agatttagat gggctaggag agcatgtgat tcacatgaca
     1441 ctcgtaggaa ctaaggagtc tcaatgaaat atcaacttaa tagtaatgtt cgtgtcgtga
     1501 catttcaaga tacattttgt tttagaaaag gaatctggga ctttaatgaa gccattctag
     1561 atttgacaca agaacctcaa aatttaaaga tagtttatca agaaatagtt tcacagttgg
     1621 ttaagggagt agccattaat actgaaactt atgaaaatac tttagaacct gagacgttcg
     1681 ctaatttaat ggaagtcatt tcaggcttgt attacaatga tatgctgatg cttgaggatg
     1741 actacaatct tgaagaaaat gtcatgaaaa ttttaatggg taatttccgt tttatggcgc
     1801 aagcaggtca tatggtaagc aatgatcctg ttttgtttat cagtgattcg acttatgtta
     1861 atgaatctgc tgagttgcta gctgaacaac tgcatttaca attgcaagtg gctagcgatg
     1921 acttaaaaat gttaattcag cagacagatg ttagttcgcg tttagatgct ttggagcatc
     1981 gccgtaacat gaattgttta tcagatgcct tgtgcgatta ccaaagtatt attatttgtc
     2041 aagagcgctt gaatattatg atgttgcgac acttgaatga agttagcgta gctatgaaaa
     2101 aacaattagt gattggtttt gtagatggac cattcttgca cgcttgtact ttgaatcctc
     2161 ctcatagtgc tgactttgat agcttagaaa gaagagtttt ggcacgttta caagactcaa
     2221 ctctctatca acattttgct aatcagattt taccagcaac acaagatgtg agccaggcct
     2281 atttaccatt gttaaatgtt ttaatgaatt tagttgttag cgaagctttc attattgctc
     2341 aaacaggtag ttctaaattt gagggacgtt tattaagcat ttacttaccg acgcttgaga
     2401 ttcaggtcca agatattttg aaaatgtcta attcacagac acaaggagct ttggcaaaat
     2461 taaagtatga ggatcagcag atatcaacac gtgagattgt taaaaaactc cttgacgagt
     2521 aacctataag gagaatctat tatgttatac tattatcctt cttttaatca tatttttgat
     2581 gaattaaaaa gtttaagtgg caatcgaaca ggtatcttaa atcaatctca agttccagtt
     2641 tgcaaccatc ctcacgatgt ttacttaaaa agtattactg gccaaatgcc agattatcat
     2701 aaacaattta taggtgagtt gagtcaagtt agttatcaca ttattggtta tggcagttac
     2761 tatgaagaag cacttatcaa gtatttagga gaaagtattg aacgctatgc tactgtaatt
     2821 gccggagact tactatcaga tcgtattgtc tatgcttctt ataatgagtt aaaactgtta
     2881 cataaagtga tgcctttaga atatttgcaa gtgtttaccc aagaacagat cgcattatct
     2941 tgtgacttgc aaatgatgat gtgcgataaa atggtaactg agaacgatgt attgggctgg
     3001 gttaaatgtc ccatgttctt tgaggacgca gagatgtatg ttccagctca aatgctttgt
     3061 gttgggtata aaacaaatga gactgtagga gaaagacgga taataccagg attttctacg
     3121 ggaacagctt ctcacaaaac gttagaagcg gctatgtgca acagtttgat tgaatacatc
     3181 cagatcgatt caatgatgct tagctggtat actaagaagc cttgccccaa gattattgtt
     3241 gatgatcctg atattgaagt gattttagaa gaagctagac tgggaaaaga cagtctatac
     3301 gacattattc ctattgatat gactgtagga gaagataatc ctctttatac gtttggaatc
     3361 attctcaaaa ataaatatga tgaagggcct tacctcttgt ttggagtgca ggctgggtta
     3421 gatcctaaac atgctttgct aagagggatc atggaagctt cagctattag ctatagttac
     3481 tactataatc ttttatatca aaaagcttcc cttgcaaata ttgaatgcga agaacctttg
     3541 tttttagatt tagatagtaa tgtcttctat tatgcacatc ccaaggacca agaccataaa
     3601 tggaaggcct ttgaaccttt gatttcagga gaagttctgt taagtgattt ggaagatcat
     3661 tctggtaaag ataaaaaaga agatttgaag actttattag cttatgctaa gaaagtcagt
     3721 cctaatgctg tctttttaga tattacacct cctgaagctc tagaaaaagg ctggtacgtc
     3781 acgcgagttc tgatgccaga acttcttgaa atgtgtatac cagcatttcc ttttgctaat
     3841 catccacgaa tgagacagtt tggaggtgta acaaatgcct ttgtccatcc aatgccttaa
     3901 tctttgtttt ttgttggtaa ctttttgtcc ttcaattcct atgcaagcta tttttggaaa
     3961 ggaagatagt ggttatgcat ttaatttaat tggttttcta agagcaactc tgatttatga
     4021 cattttggct ttggtaagta tttatgtttt gtcacctcaa ataaccttgt ctcttgaaag
     4081 tattgatagt aagacgttct ttatgggact tgtattttgc gtcttgatag tactgattga
     4141 actcattttc ttacatggtt tacgttgttg gcaaaaaaag caatggcttc ctgcaacttt
     4201 ctcgtttgta ggaacgacaa atgattggtc taagattggc tatcctttat tactagcttt
     4261 atttgaagag acgatttatc gttttttgtg gtttaatata ttagcttttc aatggcattt
     4321 accaacaatt attgttttaa ttgtaactag tttttgctat gctttaaatc acttattgat
     4381 ggggaaatcc attttttatg ctaagttggt aacaggcatc atttatggta gtatttacat
     4441 gctgactagt caattgtggt tggttgtgat aatgcatgta ggaggtaact tgctagttga
     4501 gtgtcttagc catcttcaaa caaaaaagaa gaaggaggtg acatgatgct attggttttg
     4561 ctgtcgtttt taggtctaac tactctttgg ttgaccagtt atcgaagacg ttgtttggct
     4621 agatggcatc ttcaatggtt aatggcctta tcctatcaag attttttaga tgtcttactg
     4681 agtctgtttc aatttgtcgt tattatactt gttttgttct tttactcagc tactattaat
     4741 ctaggagagg ttctgacctt tttgacacaa actagctggc attggcagat tctttgttat
     4801 ttagtgttgt atcttatggc catcatagag atgacgcttt tagttttaat tcttatcttt
     4861 gatgttttgc tccagaaaga tagtcgattg ctctttaaaa aaataacttg gctgcctttt
     4921 agacaagata aaccagtctt aagtatactt ttgctaggca tagttattct agtagacagt
     4981 ctcttttatt tgggcttgct tatattatta ggagaacagt cgctaacaag tttagcaacg
     5041 cttattttag gttatgggat agtcaaggct tgtcgctatt caggttggtt aaatgtacta
     5101 ttagcttttt gtcttttcac tatagttgga ctatgggcag ttacggcaac tttattatat
     5161 ggttggctag taggtgcgat gatattaacg gtgacttatt tgatgattag ttgcaaagag
     5221 tattagcaat attaaaaagg agtgatatat gagttttgta caattaacaa atgttgtcaa
     5281 gtcctacaaa aacggcaaga aagctgtcaa tgatgtttcc ttgtctattg aagcaggtaa
     5341 tatttatggt ttgttaggac caaatggtgc tggtaagtct accttgatta atcttatctt
     5401 aggcttgatc cctttgagtt ccggtaaaat tactgtttta gggcaatccc aaaagactat
     5461 tcgaaaaata agttcgcaga taggttatgt tcctcaagac attgctgttt atccagacct
     5521 aactgcttat gaaaatgtag aactatttgg gtcactttat ggcttaaagg gagctcagct
     5581 taaaaaacaa gttctaaaaa gtttagaatt tgtgggacta cactcccaag ctaagcagtt
     5641 tccaagtcaa ttctcaggag gaatgaagag acggttaaat atcgcttgtg cgctagttca
     5701 ttcacctaaa ttaatcattt ttgacgaacc gactgtaggg attgatcctc aatcacgtaa
     5761 tcatatttta gagtcgattc gtttgctaaa caaagaaggt gccacagtta tttatacgac
     5821 ccattatatg gaagaagtag aggctctttg tgattatatt tttattatgg atcatggtca
     5881 agttattgaa gaaggaccta aatttgaact ggaaaaacgt tacgttgcaa atctagcaaa
     5941 ccagattatt gtaactctaa cagattcacg tcatttggaa ctggcagata agcctgattg
     6001 gtctttgata gaagatggag aaaaactcat gttgaagatt gataatagtg atatgacatc
     6061 agttgttcat cagctcacac aggccaatat tacttttagc gagattagac ataaccattt
     6121 gaatttagaa gaaattttct tacacttaac aggtaagaag ttacgagatt agaggttact
     6181 atggttttat ttcatttaat caaaaaagaa agtttacaga tttttagaaa ccgaacagcc
     6241 ttattgatga tggtgatttt tccaattttg atgatcgtta ttttaagttt tgcctttaaa
     6301 tcaagtttta atactgcgac aacagtccct aaattgacca ttcgttacca attagagggt
     6361 gaaaaaacgg attaccagaa aaattttctt gcttttttaa aagttttaaa ccaaaaactt
     6421 catttagagg ctaaacctag taattctctt gaaaaagatc gacaaagggt cagtgaagga
     6481 gccttaacgg ctgttttaga agtgaagaag aatcagacca ttaaggttat tactaataat
     6541 attaatcagc aaaatgcaga tttaatcaat atgctagtaa aaaattatgt agataatgct
     6601 aaaacttatg actcgatagc agctctttat cctcaacaat taaatcatat cagaaagcga
     6661 agtgtggact atgttaaggt cagttcaata cagacaagta aaggaatgac atcagctgat
     6721 tattatgcta tttccatgtt taccatgatt actttttata gtatgatgtc tgcgatgaac
     6781 cttgttttgt cagatcgtca acaacggatt acaaatcgta ttcgcttaac aggagtttct
     6841 ccaagtcttt tagtctttgg gaaattaata ggtgctatgt tagcaacaac tgttcaattg
     6901 agtcttttat acatttttac aaggtttgtt ttacgagtta attggggcac taatgagtgg
     6961 atgcttattg gtataacagc ctccttagtc tatctctctg tagctatagg tatcgggcta
     7021 ggcataagca ttaaaaatga ggctttttta acggttgcat ccaatactat tattcctata
     7081 ttcgcctttt taggaggcag ttacgttccg ttgacaacat tacacagctc tattattaat
     7141 caattgtcga atatatctcc tattaaatgg gttaatgata gtttgttcta tcttattttt
     7201 ggtggtcaat ataatccgat tcctgtaact ttgatcgtta atattagtat cggaacaatt
     7261 tttataatat tggcattaat aggtatgaga aagcaggtga cgacatgatt tgttttataa
     7321 aaactctatt tgttaagata aagcgcaaaa aaacaagtta tgtgacattc tttttaatgc
     7381 ctattttaac gacacttttg gctttatctt tgagtttttc aaataataat caggctaaaa
     7441 ttgggatatt agataaagat aatagtcaga tatctaaaca atttattgct caactaaagc
     7501 aaaacaaaaa gtacgacatt tttaccaaaa tcaaaaaaga gcatattgat cactaccttc
     7561 aagataaatc tctagaagcg gtattgacta ttgataaagg gttctcagat aaagtgttgc
     7621 aaggaaaatc tcaaaaactc aatatacgtt cgattgctaa tagcgaaatt acagagtggg
     7681 taaaagcaca gaccaattat ctattggaaa actataatat tataggggat gtggctctag
     7741 gtaacgaaga tacttttaat agaattctcc aaaaaaacca acagttaaat tatgatgtta
     7801 agcaagtaac tttgacagac cgatcacgta gcaaagcagt atcttccaca acgacaggat
     7861 ttttgcttat tctaatgtta ggtagtacga gcgtgattta cagtggtatt ttggcagata
     7921 aatctagtca gttataccat cgattaatgt tatcgaactt atctcgtttt cgctatatgt
     7981 tgagttacgt ctgtgtagga tttgttgctt ttacgattca aattgtcatt atgctgagtt
     8041 tgttaaaagt atttaatatt agtttttttg ttccgacatc acttcttttg attatttttt
     8101 tcctttttag tttattagcg ataggctttg gcctgctgat tggagctatc acacaaaatt
     8161 cccaacaaag tagccagtta gctaatctta ttgtaatgcc gacttcaatg ttggctggct
     8221 gtttatggcc attgtctatt acgccttctt acatgcaagc aattggtaag ttattaccac
     8281 aaaattgggt tttatcagcc atagctattt ttcaaagtgg agggacctta tctcaggctt
     8341 ggccatactt gttagctcta atgggaacag cactagcttt gattattttt tcaagtttat
     8401 tattaaaacc taccagacta taattagtct tttgttaaaa aatactttcc taattagcta
     8461 actaccaggt agccctttta ttggcttata tgcaataaaa gggttgcttt ttgcttatat
     8521 tttctctagt gcacttatct tttgttaaaa gcgattgcga tgttactgtt gttactgtgt
     8581 tttttagaga gcatattatc aaaagcgacc tctctagaaa gttcgttttt gttgataaat
     8641 gagttgtcaa agtattttaa aaaaacgttt tcaataaaca taaaaactaa tgttattaaa
     8701 aaaaggtgta aaaacgtatt tattttatga aatgtttttg ttacaataag catgtatcga
     8761 atgctataaa gctgtcttgt tcgctatcag gggtgcttgt gatgttatgt cagatcaaac
     8821 aagtctttaa ttgggtgact taacagatta aaagaaaaga tctaatcgtg ttacttgata
     8881 gtataattaa tgcaaacaga aagtgtatcc caattcatag tctcaggtgg aggttaatat
     8941 tcaaaaataa aatcttgttg ttgtcttaaa ctaatcacat taaaaggaga tatcatgatt
     9001 aacaagaaat atataatacc tgtttcattg ttgacactag ctattacgct tactagtgtt
     9061 gaagaagtta cttcacgcca aaatttgact tatgccaatg aaatcgtaac acaaaggcca
     9121 aagagagaat ctgttattag tgataaatcg aattttcccg tcatatcacc ttacctagca
     9181 agtgtggatt ttggtgagag aaaaacatct ttgccaacac ctgataaagg agtaaaagta
     9241 actactgaac agtctattgc tcaagtaaga aaggggcctg aagaaagaac ctatactgtt
     9301 actggcaaga ttacgagtgt gatcaatggc tggggaggct atggctttta tattcaagat
     9361 agtgaaggta ttggacttta tgtttatcct caaaaagatt taggatacag taagggagat
     9421 attgttcaat taacaggtac acttactcgc tttaaaggtg atttacaact ccaacaggtg
     9481 actgcacaca aaaagttaga gttatctttt ccgacttctg ttaaagaagc agtaatatca
     9541 gaattagaaa caacaacacc ctcaacatta gttaagttat ctcacgtgac agttggagaa
     9601 ttatcaactg atcaatataa caacacatct ttccttgtaa gggatgatag tggtaaaagt
     9661 atagttgttc atatagatca tcgtacaggg gttaaagggg ctgatgttgt tactaaaata
     9721 agtcagggtg atttgattaa cctcacagcc atattgtcta ttgttgatgg tcagttacaa
     9781 ttaagaccgt tttctcttga acaattggaa gtggttaaaa aggtcacaag ctcaaatagt
     9841 gatgcttcat ctcgtaatat tgtgaaaata ggcgagattc aaggagctag tcatacgtcg
     9901 ccacttctca aaaaagcggt caccgtagaa caggttgttg tcacttattt agacgattcc
     9961 actcattttt atgttcaaga tcttaatggt gatggtgatt tagcgacttc agatggtatt
    10021 cgtgtttttg ctaaaaacgc taaggttcaa gtcggcgatg ttttgaccat ttcaggtgaa
    10081 gtggaagaat tctttggtcg tggttatgag gaacgtaagc agactgacct taccatcacc
    10141 caaattgtgg ctaaagcagt gatcaaaaca gggacagctc aagttccatc accgcttgtt
    10201 ttagggaaag atcgtatcgc gccagccaat attattgata atgatggctt gcgtgtgttt
    10261 gatccagaag aagacgctat tgattattgg gaatcaatgg aaggcatgtt agtggcggtt
    10321 gatgatgcta aaatccttgg tccaatgaaa aataaagaaa tttatgtctt acctggctct
    10381 agtacaagac cgttaaataa ttcaggtgga gtattacttc cagctaattc ttataacaca
    10441 gatgtgattc ctgttctttt caaaaaaggc aaacaaatta ttaaagcagg agactcttac
    10501 aaaggaagat tagctgggcc agtatcttat agctatggta attacaaggt ctttgttgat
    10561 gacagcaaaa acatgccaag tttaatggat ggtcatctaa aacctgaaaa aacaaacttg
    10621 caaaaagacc ttagcaagtt aagcattgct tcttacaata ttgaaaactt ctcagccaat
    10681 ccttcttcaa ctaaagatga gaaggtcaaa cggattgccg aatcctttat tcatgatctg
    10741 aatgctccag acattattgg attaattgaa gtccaagata ataatgggcc gactgatgat
    10801 gggacaacgg atgcgacaca aagcgcacaa cgcctcattg atgctattaa aaaactaggt
    10861 ggcccaactt atcgttatgt tgatattgct ccagaaaata atgttgacgg aggtcaacca
    10921 ggtggtaata ttcgaacagg attcctttat caaccagagc gcgtcagcct ttctgataag
    10981 ccaaaaggcg gtgctcgtga tgctctaact tgggttaatg gagaattaaa ccttagtgtt
    11041 ggtcgaattg atccaactaa cgccgcttgg aaagatgttc gtaaatcact agcagcagaa
    11101 tttatcttcc aaggtcgtaa agtcgttgtt gttgcaaatc atttgaactc taagcgtggg
    11161 gataatgctc tttatggttg tgtgcaacca gtcactttta aatctgagca aagacgtcac
    11221 gtcttggcta atatgctagc acaatttgcg aaagaagggg caaaacacca agctaatatt
    11281 gtgatgctag gtgactttaa tgattttgaa ttcacaaaga cgattcaatt aatcgaagaa
    11341 ggtgatatgg ttaacttggt gagccgacat gatatttcag atcggtattc ttattttcac
    11401 caaggcaata atcagaccct tgataatata ttagtttcac gccatttact tgatcactac
    11461 gaatttgaca tggttcatgt gaattcccca tttatggaag ctcacggacg cgcatcagat
    11521 catgatccat tgttacttca attatcattt tccaaagaaa atgataaggc agagtcttct
    11581 aaacaaagtg taaaagctaa aaaaacttca aaaggaaaac tgttgccaaa aacaggagat
    11641 agtcttgttt atgtgataac gctactagga acggctagtt tattagtgcc tattttatta
    11701 ttgactaaag gcaaaaagga atcatagcga tttgaagaat tggagttcat aaagagtcgt
    11761 taaaggcttg atatacttat gttagacctt aagctaaaat ggatgactat ataaaaacta
    11821 atattgataa caaaagaaga taacaataag acagctttac ttgctaaaga cttttgtcaa
    11881 gctaattgtt ttatggtaca atgtaaccgt tgctttgcaa cccttggtgc ttagttccct
    11941 ttcaccaagc atattagaaa cgtagatagc ttttgagagt tatccagacg ttaaaggaga
    12001 aaaaatgaca aaattgactg tacacgacta tgttcacatt gggctagtag ctgccttgta
    12061 tgttgtctta actattaccc cgcctctaaa tgcgatttct tatgggatgt atcaatttag
    12121 aatatctgaa atgatgaatt tcttagcttt ttatcatcgc aagtatatta ttgcggtgac
    12181 tcttggatgt atgattgcta acttttatag tttcggactg attgatgtct ttgtaggcgg
    12241 cggttcaact cttatttttg tgaccttagg tgttattttg tttagtaagt atcaaaaaga
    12301 ttatcttttt aatggcattt ttaataaagc ttttgtttac ttttctttct tttttgcaac
    12361 ttccatgttt actgtagcaa tcgaacttta cttctttgga gctccatttt tattaacatg
    12421 gtttacaact gcgttgggag aattagtatc tctgctcata ggatcactta ttattgataa
    12481 gttgtctcaa agaatttcct tttagtaatg catcatactc aaaagagttg ggtcaatacc
    12541 cttctctttt ttatgttgtt tgtaatgtta aaatcgttct agatagaaat atttaacact
    12601 ttagctaata gtaccatatg gagtggccaa cgattacttt tgatgttgtt atgatataga
    12661 aatagctcat ttgttatctt ttatgataaa ataaaagtat gaaaaaacgc ataaaagaat
    12721 taacagatct tcttaaccgt taccgttatg actattatac taaagatgcc ccatcagttt
    12781 ctgacagtga ctatgataag ctttatcgtg aactggtgac tttagagcag tcatatcccg
    12841 agtatgtctt gcaagatagc ccaacgcagc aggttggagg gactatttta aaggggtttg
    12901 aaaaatatcg acatcagtat ccgcttttta gtttgcagga tgctttttca cgtgaggagc
    12961 tggatgcttt tgataagcgc gtcaaggccg aatttccgaa tgccacctat ctagcagagt
    13021 taaaaattga tggtttatct atttccttga gttatgagaa tggcttctta caggttggag
    13081 caacacgggg tgatggcaat atcggtgaaa atatcacaga aaatattaaa aaaataaagg
    13141 atattcctca ccaattgagt gagcctttaa ccatcaccgt tcgaggagag gcttacatgt
    13201 ctcgtcagtc ctttaaagcg atcaatgaag cacgccaaga aaatggggag actgaatttg
    13261 ctaatcctag aaatgctgcc gctgggacac taaggcagct agatacggca gtggttgcta
    13321 agcgtcaact agccactttt ttgtatcaag aagctagtcc gacagctaga aatcaacaaa
    13381 atgaggtctt agcagaatta gcagatctag gtttttcagt aaatccgtat tatcaactca
    13441 catcgtctat ggatgagatt tggaatttta tcaaaactat tgaggcaaaa agagatcaat
    13501 tagcttatga catagatggc gttgttatta aagttaatag cctagccatg caagaagagc
    13561 tagggtttac ggttaaagct ccacgctggg ctattgctta caaatttcca gcagaagaaa
    13621 aagaggcaga aatcctttcg gttgactgga cagtgggacg aacaggcgtg gtcacaccta
    13681 cagcgaatct aactcctgtg caactagcgg ggacaaccgt gagtcgtgca accctacata
    13741 atgtggatta tattgccgaa aaagatatcc gtattggcga tacagtgatt gtatataagg
    13801 caggggacat tattcctgct gtcttaaatg tcgttatgag taagcggaac cagcaagaag
    13861 tcatgcttat tcctaaacta tgcccatctt gtggtagtga attagttcat tttgaagatg
    13921 aggttgcttt gcgttgtatt aatccgttgt gtcctagttt gattcagcga agtttggagc
    13981 attttgcaag tcgtgatgcc atgaacatta ctgggctggg accagctatt gtggaaaaac
    14041 tatttttagc ggggtttgtt catgatgttg ctgatattta ccagttgacc aaagaagatt
    14101 tcatgcaatt agatggcatc aaagaaaagt cagctgataa attgctcgct gcgattgagg
    14161 cttctaaatc aaattcagct gaaaaactgt tatttggtct gggaattcgt catattggct
    14221 ctaaggttag tcgcttaatt ttagaggtat acggagatat ttctgctctt ttaaccgcta
    14281 aagaagagga aatcgcaagg atagatggtc ttggctcaac gattgctcaa tcacttactc
    14341 aatactttga acaaaaaacg gctgcgattt tagtagacga gttaaagaca gcaggtgtca
    14401 acatgcatta ctcaggtcaa aaagttaata gtgacgcagc gctttttggt ctaactgttg
    14461 ttttaactgg caaattaaat cagctgaacc gaaatgaggc caaagataaa ttagaggcat
    14521 taggtgccaa agttactgga agtgtatcta agaaaacaga tttagttatt gcaggtagtg
    14581 acgctggttc taagctagaa aaagcaaaga gcttaggaat tcggattgaa gatgaagatt
    14641 ggctacgaaa gctttaagtg aggtaatgtt atgaaaaaac aattgagagc acgtctcatt
    14701 tataatccaa cgtcaggaca agaacttatg agaaaaagtg ttcctgaagt tttagacata
    14761 ttagaagggt tcgggtatga aacatctgcc tttcaaacaa cagcccaaaa gaactctgct
    14821 ctaaatgaag caagaagagc ggcaaaggca ggttttgact tattgattgc tgctggaggt
    14881 gatggcacta ttaacgaagt ggtcaatgga attgctccct tgaaaaagcg ccctaaaatg
    14941 gccattattc caacaggtac cactaatgat tttgctagag cgttaaaagt accaagagga
    15001 aatccgagcc aagcagcaaa acttatcgga aaaaatcaga ctatccagat ggatattggt
    15061 agagctaaga aagatactta tttcatcaat attgctgcag caggaagttt gacggaatta
    15121 acttacagtg taccaagtca gttaaaaacg atgtttggat acttggctta tcttgctaaa
    15181 ggagtagaac tgctcccaag agttagcaat gtgcctgtta aaattacgca tgacaaaggc
    15241 gtctttgaag gtcaagtttc tatgattttt gcagctatta ccaattctgt tgggggattt
    15301 gaaatgattg ctcctgatgc aaaactagat gacggtatgt ttacgctcat tttaataaag
    15361 acagcaaatc tttttgaaat tgtacatctt ttgcgtttga ttttggatgg tggtaagcat
    15421 attacagatc gtcgtgtcga atacattaag accagtaaaa tagtcattga accccaatgt
    15481 ggtaagcgaa tgatgattaa tttagatggc gagtacggag gagatgctcc aattacatta
    15541 gagaacctaa aaaatcatat cacttttttt gcagatactg atttgatttc tgatgacgct
    15601 ttagtcttag atcaggacga attggaaatt gaggaaatcg taaagaaatt tgctcatgaa
    15661 gtagaagact tagaacaaga attagaagaa taatacaata gttattagct actgacagtt
    15721 tagtcaaatg cactactatt agaatctaag atttttaaat caattgaggt agtgtttttt
    15781 gatgtgctca aagagtcaat ttattcatat gaggggccta tttgaggtct ctcttttttg
    15841 atcatatgca agaaaatgcc atgttttagg ggtgttatta tacccttttt ggaatcttgt
    15901 tgcctttttg ttataataag agtgtaattc tatttttaaa aagatcttaa caaagacaga
    15961 ctcgtttatc aaaaaggtta gtattagtct aagaaagcgt actcagtcta aagaaatctg
    16021 ttgacattct taattttaag gaatagaata gcaaagtaaa aaaaatttaa aggagtattc
    16081 tactatgaat cctattttcg cattggcttt ggcctgtttt ggtgtttctc ttgccgaagg
    16141 tttcttgatg gcaaatcttt ttaaagcagc atctcgccaa ccagaaatca ttggtcaatt
    16201 acgttcatta atgatcttgg gtgttgcctt tatcgaaggt actttctttg ttacccttgt
    16261 tatggccttc attcttaaat aacagcctat ttgataatag aaaaggaggg tgttagatgg
    16321 aagaagctaa aatacccatg ctaaagcttg gtccaataac ctttaatttg accctacttg
    16381 ctgtttgtat tgtcacaatt gctgttatct ttgcctttgt tttttgggca agtcgccaaa
    16441 tgaaattgaa accagaaggg aagcaaactg ctttagaata tttaatcagt tttgtggatg
    16501 gtattggaga agagcactta gatcataatc tacaaaaatc ttattcgctg ttactcttta
    16561 ccatttttct ctttgtggct gtcgctaata atttagggtt atttactaag ttagagacag
    16621 ttaatggcta taacctatgg acctcgccaa cagccaatct ggcttttgac cttgctctat
    16681 ctctttttat taccttaatg gtacacattg aaggggttag acgtcgtggc ttggttgccc
    16741 atttgaaacg tttggctaca ccgtggccaa tgactccgat gaatttatta gaagagttca
    16801 caaatttctt atcacttgcc attaggttat tcggtaatat ctttgccggg gaagttgtta
    16861 caggtttgat tgttcaactg gccaattatc gagtttattg gtggccgatc gctttcctag
    16921 tcaatatggc gtggacagcc ttttcagtct ttatttcctg catacaggct tttgttttca
    16981 caaaactaac agcgacctat ctaggaaaga aagttaatga atcagaagaa taaggaagga
    17041 gaacaaacga atgtcaatca catttggtga actcgttggg aattttattc tagtaacagg
    17101 ttctgtaatc gtcttgttac tcttgatcaa aaaattcgct tggggtgcaa ttgaatcgat
    17161 tttacagaca cgctcacaac aaatctctcg agatattgat caggctgagc aatcacgtct
    17221 aagtgctcaa cagttagagg caaaaagtca agctaaccta gatgctagtc gttcacaagc
    17281 aagtaaaatc attagtgatg ccaaagaaat tggtcaatta caaggtgata aattggtggc
    17341 agaagctact gatgaagcaa aacgcttgaa agaaaaagcg ttgacagata ttgaacaaag
    17401 caaatcagac gctatctcag cagtcaaaac agaaatgtct gatttaacgg ttcttttagc
    17461 ggaaaaaatt atgggagcca atcttgataa gacggcgcaa agccagctta ttgacagtta
    17521 tcttgatgac ttaggagaag cttaatgacc aaaaaagaac aggctattat cgagcaatat
    17581 gcaaaaagcc ttgttgaggt agcaagtgaa catcattctc ttgatacctt acaagctgat
    17641 gtgcttgcga ttttagagac gtttgaaaca actaatcttg atcaaagtct atcaagtcta
    17701 gctgttccgc atgctgaaaa aataaaattg ctaaccttat taaagggaaa taattctgtt
    17761 tatatgaata atttcttgaa tctcatttta caaaacgaac gtgaagctta tttgtatcaa
    17821 atgcttcagg ctgttttaaa tgaaattgca atagtttcaa atcagtatga tgtgactgtt
    17881 acctcatcac tacctttgac tgaggagcaa aaaaaccgtg ttcgagcagt tgttgcaaag
    17941 aaatttgctg taacagcggg tcgtttaatt gaaaaagtag atccttcgct tattggagga
    18001 tttattatca gcgtcaataa taaagtaatt gataccagta ttcgtcgtca attgcaagca
    18061 tttaaaatga atttaaaata gaaagtggtg tgacttttgg caattaatgc acaagaaatt
    18121 agcgctttaa ttaaaaagca aattgagaac ttccagccaa atttcgatgt cacagaaact
    18181 gggatcgtta cctatattgg tgacggtatt gcacgtgccc gtggattaga taatgccatg
    18241 agtggtgaac ttcttgaatt tgaaaatggt gcctatggga tggctcaaaa ccttgagtca
    18301 aatgatgtgg gtattattat tcttggtgat ttttcagcaa tccgtgaagg agatgtggtt
    18361 aagcgcaccg gtaaaatcat ggaagtacca gttggtgaag ctctcattgg acgtgtggta
    18421 aacccacttg gacaaccagt tgatggcttg ggagatattg aaacaactgg ctttagacca
    18481 gtagaaacgc cagctcctgg tgttatgcag cgtaaatccg tttctgaacc cttacaaact
    18541 ggattaaaag caattgatgc tttggttcca attggtcgtg ggcaacgtga gttgattatc
    18601 ggagaccgtc aaacaggaaa aacatccgta gctattgatg cgattttgaa ccaaaaaggt
    18661 caagacatga tttgtatcta tgtggctatt ggtcaaaaag aatcaaccgt tcgtacacaa
    18721 gttgaaaccc ttcgccgtta cggtgccttg gattatacta ttgttgtgac agcgtcagcc
    18781 tcacaaccat caccattgct cttcatcgct ccttatgcgg gtgttgccat ggctgaagaa
    18841 tttatgtacc aaggcaagca tgtattgatt gtctatgatg atttatcaaa acaagcggtg
    18901 gcttatcgtg aattgtctct cttgcttcgt cgtccaccag gtcgtgaagc ttacccaggg
    18961 gatgttttct acttgcatag ccgtcttttg gaacgctctg caaaagtttc tgatgactta
    19021 ggtggaggtt ctatcacagc tctaccattt atcgaaacac aggccggaga tatctctgca
    19081 tatattgcga ctaacgttat ttcgattaca gacggacaaa tcttcttgca agagaacctc
    19141 tttaattcag gaattcgtcc agcgattgat gcaggatcat ctgtctcacg tgtaggtggt
    19201 tcagctcaaa ttaaagcgat gaaaaaggtt gctggtactc ttcgtttgga tttggcttcc
    19261 tatcgtgaat tagaagcctt tacccaattt ggttcggacc ttgatgctgc aacacaagca
    19321 aaacttaatc gtggtcgccg tacggttgaa atcttgaagc aaccattgca taaaccgtta
    19381 cctgttgaaa agcaagtcgt tattctttat gcccttactc atggtttctt agatgatgtt
    19441 cctgtagatg atattttggc ttttgaagaa gctctttacg actactttga cgttcattac
    19501 aatgatttat ttgaaactat ccgtaccaca aaagaccttc ctgaagaagc tgcccttgat
    19561 gccgctatta aagcgtttaa agaacactca aactttaagt catagaggga ggatactagt
    19621 atggcaggct ctctaagtga aattaaagct aaaattattt caactgagaa aacaagtaaa
    19681 atcactagtg ccatgcgtat ggtttcttct gcaaaacttg ttaaatctga gcaagcagct
    19741 cgtgattttc aaatttacgc ctcaaaaatt cgccagatta ctacagattt attgaaatca
    19801 gaattaacca taggatctga taatccgatg ttggtgtctc gtcctgtcaa aaaaacaggc
    19861 tatattgtca tcacgtctga taaaggactt gttggaggtt acaattcaaa aatcttgaaa
    19921 tctgttatgg atatgattac agagtaccat gctgatggtg actatgaaat catttctatt
    19981 ggtagtgttg gttcagactt cttcaaagca agagggatga atgtggcttt tgaacttcgt
    20041 ggacttgcgg atcaaccaag ttttgaacaa gtgagacaaa tcatttcaca atccgttgac
    20101 atgtttgtca atgagatttt tgatgagtta tatgtctgtt acaatcacca tgtgaatagc
    20161 ttaaccagcc aagtccgtgt tcaacagatg ttgccaattt ctgacttggt tgctgatgaa
    20221 gcagcagaag aaggtgttac tgggtttgaa ttggaaccta atcgtcatga tattttagat
    20281 caattgttac ctcaattcac agaaagttta atttatgggg ctatcattga tgctaaaacg
    20341 gctgaacatg cagcaggtat gactgctatg cagacagcga cagataacgc taagaatgtc
    20401 attaacgatt tgaccatcca atataaccga gctcgtcaag cagcaattac acaagaaatt
    20461 actgaaattg ttgcaggagc aaatgcacta gaataaaaaa taacgctgac tagcgattag
    20521 gttattgtca gcattcaatt ttatcaatcg agataaaatg acttatggga cttttctatt
    20581 gaaagactgc tcttttcagt ataaaagaag ttagcaagac taactaagcc ctgactatcg
    20641 aatataagga gaaatgaatg agctcaggca aaattgctca ggttgttggt ccagtagtag
    20701 acgtcatgtt tgctagtggg gacaaacttc cagagattaa taatgcattg attgtttata
    20761 aagatagtga taaaaagcaa aaaatcgtcc ttgaagttgc actggaactt ggtgacggta
    20821 tggtgcgaac aatcgctatg gaatcaactg atgggcttac acgtgggtta gaagttcttg
    20881 acactggtcg tgcgattagc gtaccagtag gtaaagaaac tttgggacgc gtctttaatg
    20941 tacttggaga aaccattgat ttggaagaac catttgcaga agatgttgac cgtcagccga
    21001 tccataaaaa agcaccatcg tttgatgaat tatcaacatc atcagaaatt cttgaaactg
    21061 gtatcaaggt aattgacctt cttgcccctt accttaaagg tggtaaagtt ggacttttcg
    21121 gtggtgccgg agttggtaag actgtcctta tccaagaatt aatccacaat atcgcccaag
    21181 aacacggagg tatttcagta tttaccggtg ttggtgagcg aacacgtgaa ggaaatgacc
    21241 tttactggga aatgaaagaa tcaggcgtta ttgaaaaaac cgccatggtt tttggtcaga
    21301 tgaatgagcc gcctggggca cgtatgcgtg tagcacttac tggtttaacc attgctgagt
    21361 atttccgtga tgtagaaggc caagatgttt tgctctttat tgataatatc ttccgtttca
    21421 ctcaggcagg ttcagaagta tcagccctct taggccgtat gccttctgct gttggttacc
    21481 aaccaaccct tgctactgaa atggggcaat tgcaagaacg gattacatca actcaaaaag
    21541 gatctgttac atctatccaa gcgatttatg taccagcaga tgattatact gaccctgcgc
    21601 cagcaacagc atttgctcac ttggattcaa caactaacct tgaacgtaaa ttgactcaaa
    21661 tgggtattta tccagccgtt gacccattgg cttcaagttc acgtgcttta tcacctgaga
    21721 ttgttggtga agagcactat gctgtggcaa cagaagttca acgtgtgctt caacgctacc
    21781 gtgaattaca agacatcatc gctattttgg ggatggatga attgtcagat gaagaaaaaa
    21841 cattggttgg acgtgcgcgt cgtatccagt tcttcctctc acaaaatttt aacgttgctg
    21901 aacaatttac cggtcttcct ggttcttacg tgccagttgc tgagacagtt cgcggcttta
    21961 aagaaattct tgaaggaaaa tacgatcacc ttccagaaga cgcctttcgt tcagttggtc
    22021 caatcgagga tgtgataaaa aaagccgaaa aaatgggctt ttagtgaggt gatgccatga
    22081 cacaaatgac tgttcaagtg gtaacgccag atggaatcaa atatgatcac catgctaaat
    22141 gtatttctgt aacaacacca gatggggaaa tggggatttt acctaaccac atcaatttaa
    22201 ttgcaccctt gcaagttcat gaaatgaaaa ttcgccgagg tggtgaagat gaaaaagtgg
    22261 actggattgc tatcaatggt ggtattattg aaatcaagga taatgtggtt actgttgtcg
    22321 ctgattctgc agaacgtgac cgtgatatcg atgtcagccg agcagagcga gcaaaactaa
    22381 gagcagaacg tgaaattgca caggctgaaa cgacccacaa cattgatgaa gttcgtcgtg
    22441 ccaaggttgc cttgcgccgt gctttgaatc gtatcaacgt tagtaaaaaa taagtggtgt
    22501 tgataaaaga caaggataag taagaaaggt ttttaaccta atattttgtt tgctgagtct
    22561 ttttaacatc agtttctgag agtttgacca tactaccttc tctaaacacg ttattattgt
    22621 tgagaggagt tatatggggg aactcttttt tgtgtccacg ttgttagtag aaactcagta
    22681 atgacgctta atatattttt aggctatcaa cttagtcaga gaggatgtca acttaattga
    22741 taagttggac ggatcaagat ggtatgttat aataatccta tggaattatt aatgaagatc
    22801 attgcctttt cgtgtcattt attttttatt ggccttagtt accaattatt gattagtgtg
    22861 attgactgga caaaatttag tcattatcat ccagaaaatc ttggccggct acgacttttt
    22921 gtctttttat tagctactgc cctagggtat ttggtgagcc attgtatgct ggaattgctt
    22981 caaattagcc agacgctctt ttttgagttc cgctaatact ggaataaaag aagtatggta
    23041 taattttact acgactaaga gatagataag ggagaaaatt gtggataaaa taatcattga
    23101 aggtggtcaa acacgcttag aaggagaagt tgttattgag ggtgctaaaa acgcagttct
    23161 tcctttactg gcagcatcta ttttaccttc aaaaggaaaa acaattctta gaaacgttcc
    23221 tattctatct gatgttttta ccatgaataa cgtggtacgt ggtttagata ttcgtgttga
    23281 ttttaatgaa gcagctaacg aaatcacagt tgatgcctca ggacacattt tagatgaagc
    23341 cccttacgag tacgtgagcc aaatgcgtgc ctctattgtt gttttaggac caattttggc
    23401 acgtaatggc cacgcaaaag tatcaatgcc tggaggctgt acgattggca gtaggcctat
    23461 taatttgcac ttaaaaggat tagaggctat gggggcaacg attactcaaa aaggtggaga
    23521 tattactgct caagcagatc gactgcaagg tgccatgatt tatatggact tcccatctgt
    23581 aggagctacc caaaacttga tgatggctgc cactttagct gatggtgtga ccactattga
    23641 aaatgctgct cgtgagcctg aaattgttga tttagctcaa tttttgaata aaatgggagc
    23701 tagaattcgt ggtgctggaa cagagacgtt aacgataaca ggcgtcacgc atttacgagg
    23761 cgtagaacat gatgttgttc aagatcgtat agaagccggt acatttatgg ttgcagcggc
    23821 gatgacttca ggcaatgttt tgattagaga tgctgtttgg gaacataatc gtccattgat
    23881 ttcaaaatta atggaaatgg gtgtttctgt aacagaagaa gaatacggta ttcgcgttca
    23941 agcaaacacg ccaaagctca aacctgtaac ggttaaaacc ttgcctcatc caggttttcc
    24001 aacagacatg caagctcaat ttacagcttt aatggcagtg gtcaatggag agtctactat
    24061 ggttgaaact gtctttgaaa atcgatttca acatctggaa gaaatgcgac gcatgggctt
    24121 acaatctgaa atccttaggg aaactgccat gattcatggt ggaagacaac tgcaaggtgc
    24181 tcctgtgatg tcaacagatt tacgtgccag tgctgccctt atcttgacag ggattgttgc
    24241 tcaaggagtt acaatagtta ataatttggt tcatttagat cgtggctact atcaatttca
    24301 tgaaaaatta gcaaagcttg gagctactat tagtcgtagc agtgaggtct agcttatgac
    24361 aaatggttta aaatatgtct tagaacaaat gttattactt ttcataattg ctgccttggc
    24421 gtgtcttttt ttagccattg gacttatgat tggttatagt tttatgggag atggccagag
    24481 tccatggcat attttatcta tggataagtg ggcagagtta gtgaataaat ttactggaaa
    24541 gtaggccttg cctacttttt atagcatctg agaggaagta tgttaacaag gaaaaaacga
    24601 aaaagggtgc aagagcaaaa ggttcctaaa agagctaatg ccttacttac taagtcgaca
    24661 cgacagtatc gaaatcgcta tcaaacggat aatgcttatc gtaccttcaa gccagcaggt
    24721 tggcaccgat tgcaccactt aaaaggaagt tatgatcacg cggttgatag agggcatttg
    24781 ctaggttatg ctttagttgg tggactgaaa ggttttgatg cttctaccgg taatcctgat
    24841 aatattgcca ctcaactaag ttgggctaat caagcaaata aaccctactc gacaggtcag
    24901 aattactatg aaggtttagt atgtcgtgct ttagataagg ggcatcgcgt ccgctaccgt
    24961 gtcaccctac tttatgatgg tgataatcta ctagccagcg gtagccattt ggaggctaaa
    25021 tcctctgatg acagcttgac ttttaacgtg tttgttccaa atgtccaagc aggattgacc
    25081 gttgactatc ggacgggaca aatagctatc aatctctaag cgaaaagtca ctgatttaag
    25141 attgtcacta agcacttttt ttgatagaat agaactaatt gaataagtgt ctatgagact
    25201 agtactaata gagaaattaa cagggagtga gggccgtgac tggaagcctt cttaagggaa
    25261 ctattaggaa ttcactcagc taaagacaat taattaaggt ctgataacat cagataaaaa
    25321 cggatggtac cgcgtgtcaa cgctccgctt atcaagtgga ggagtggcac gcttttttca
    25381 tcgctaaaag aagggaaaac tatggattta caagcacaat tagaggaatt aaagacaaaa
    25441 acattggaga ccttacagtc tttgacgggt aatcatacca aagaactgca agatttgcgc
    25501 gtggctgttc ttgggaaaaa gggatctttg acagaattac taaaggggct aaaagacttg
    25561 tctaatgact tgcgtcctgt ggttggtaaa caggtgaacg aagttcgtga cttattgaca
    25621 aaagcctttg aagaacaggc caaaattgta gaagctgcta aaattcaggc ccaacttgat
    25681 gctgaaagca ttgatgtgac tttaccgggt cgtcaaatga ctttggggca tcgtcatgtg
    25741 ttgacacaaa ccagtgaaga aatcgaagat attttcttag gaatgggttt tcagattgtt
    25801 gatggctttg aggtggaaaa agattattac aactttgagc gcatgaattt gccaaaggat
    25861 caccctgccc gtgacatgca agatacgttt tatatcacag aagaaatctt gttacgaact
    25921 cacaccagtc ctgtgcaggc ccgtactctt gatcaacatg atttttcaaa agggccttta
    25981 aaaatggttt ctccaggtcg tgttttccgt cgtgatactg atgacgctac ccactcacat
    26041 caattccatc aaattgaagg tttggttgtg ggcgaaaata tttccatggg agacctcaaa
    26101 gggacccttg aaatgatcat caagaagatg ttcggtgacg aacgtagcat tcgtttgcgc
    26161 ccgtcatatt tcccgttcac agaaccatct gttgaagtgg atgtttcttg ctttaaatgt
    26221 ggtgggaaag gctgtaatgt ctgcaagaaa acaggatgga ttgaaattct tggtgctggt
    26281 atggttcacc caagtgtctt ggaaatgtca ggtgttgatg caaaagagta ttcaggcttt
    26341 gcctttggtt taggtcaaga gcggattgcc atgttgcgtt atggcattaa tgacattcgt
    26401 ggtttctatc aaggcgacca acgtttctct gaacaattta actaaaacga gtcgtttgaa
    26461 gacctctgtc agctatttta tctaagattg agtgaaagtt gataggtaat gataataggt
    26521 taattgtcta aggagaaagt ccctctcgct tcaacgtcat aagggttttg acttggaact
    26581 taaaatacga aaggaaatga ctcaaatcac ggcttgagag ctttctctag ccgagtgatt
    26641 tgggcactaa aattatgtta gtatcttata aatggttaaa agaattagta gatatcgatg
    26701 tgacaccggc agcacttgct gagaaaatgt cgacaacggg tatcgaggta gaaggaattg
    26761 aagtccctgc agatggttta tcaaaactgg ttgtggggca tgtgctttct tgcgaagatg
    26821 tgccagagac acatttgcat ttgtgtcagg tagatacagg tgatgaaacg ccacgtcaaa
    26881 ttgtgtgtgg cgcaccaaat gtgaaagcag ggattaaggt tatcgtggct gtgccaggtg
    26941 ctcgtattgc ggataactat aaaatcaaaa aaggcaaaat ccgcggcatg gaatctcttg
    27001 gcatgatttg ttccttgcaa gaacttggtt tgtcagatag tattattcca aaagaatttt
    27061 cagatggtat tcaaatcttg ccagaggagg ctgtgccagg tgatgctatt tttaaatacc
    27121 tggacttgga cgatcatatc attgaattgt ccattacacc taaccgtgct gatgcgcttt
    27181 ctatgcgagg tgtggcacat gaagtcgcag ctatttatgg caagtcagta tcattccccc
    27241 aaaaaaatct acaagaatct gataaggcaa cttcagaagc cattgaagtg gccattgcct
    27301 ctgataacgt tctaacttac gctagccgtg tcgttgaaaa tgtcaaagtt aagccaagtc
    27361 cacaatggtt gcaaaacctt ttaatgaatg ctggtattcg tcctattaat aatgtggttg
    27421 atgtgaccaa ctatgtgctc ttgtattttg gtcaacctat gcatgctttt gattatgata
    27481 aatttgaaga ccataagatt gtggcgcgtg cggctcgtca aggggaaagt ttagtcacac
    27541 ttgatggtga aaaacgggat ttgaccactg aggatcttgt tattaccgtg gctgacaaac
    27601 cagttgcttt ggcaggtgtt atgggtggtc aagccactga aattgatgcc aactctcaga
    27661 cggttgttct tgaagttgct gtttttgatg gcaaatcgat tcgtaaaacc agtggtcgtt
    27721 taaaccttcg ttcggaatcc tcttcacgtt ttgaaaaagg ggttaactat gcaactgttt
    27781 tagaagcgct tgactttgca gcggctatgt tacaagaatt agcagaaggt caagtcttat
    27841 caggccatgt tcaagctgga caattgccaa cagaacctgt tgaagtctca actagccttg
    27901 actatgtgaa tgttcgttta ggaacagaat taacttttgc tgatattcaa aggatttttg
    27961 accaacttgg atttggtcta acaggagatg aaacaagctt cacggtagct gttcctcggc
    28021 gtcgttggga tgttagtatt ccggctgatt tggtggaaga aattgcgcgt atttatggtt
    28081 atgataagtt gccaacaacc ttaccagagg taggaggaac ggctgcagaa ttaacgccaa
    28141 cacaggctct tcgtcgtaag gtccgtggtt tagcggaagg attgggcttg actgaaatca
    28201 tttcgtatgc tttgacaaca ccagagaaag ctgttgagtt tgcagtggca ccaagtcact
    28261 tgacagaact catgtggccg atgtctgtgg aacgttcagc gcttcgtcaa aatatggttt
    28321 cagggatgct agatacggtt gcctataatg tggctcgtaa acaaagtaac ttggctcttt
    28381 atgaaattgg aaaaatcttt gaacaagaag ctaatccaaa agaaaacctt cctaatgaag
    28441 tgaaccattt tgcttttgct atttgtggct tagtggcaca aaaagatttc caaacccaag
    28501 ctcaggcagt ggatttttac catgctaaag gtatcttgga tactttattt gcaaacctta
    28561 acctcaaggt tcaatatgtg ccaaccaaag acctagcaag catgcaccca ggacggacag
    28621 cgcttatcct attagatgag caagtgattg gatttgttgg tcaagttcat ccaggaacag
    28681 caaaggctta tagtattcca gaaacctatg tggcagaatt gaatatggcg gctttagaag
    28741 cagcgttgtc aagtgatcaa acttttgtgg agattaccaa attccctgct atgacacgtg
    28801 atgttgcctt gttacttgac cgtgaagtga gtcatcaggc cattgtaaca gctattgaat
    28861 cagcaggtgt aaaacgcttg actaagatta agctctttga cgtgtatgaa ggagtaacta
    28921 ttcaggctgg caaaaaatca atggcttata gccttacttt ccaaaatcca aatgacaatt
    28981 taacggatga agaagttgcc aaatacatgg agaaaatcac caaatcattg acagaacaag
    29041 tcggtgctga agtacgctaa gaaaaaaaac tgggcctcta aggctccgtt tttttctgtt
    29101 ataatagagg aaaaaagaac tccagttcaa atgattggag aaaaacatca gaaggtggag
    29161 gaaaatcaga atgtatcaaa caaaaataac aggcaaccgc ctttaccgca cggtttcgaa
    29221 aggctacgga gatagtgtaa ccttatttgg aaaaactgat caaggggaaa cccctatgag
    29281 tttactggtt attgccttgt cttcttgtgt gactatgtgt gtgcagggtt tttaccatcg
    29341 tcaatttcag caagacacac ttgctgtttc tgttgaggct agttatgagg aagaagtttt
    29401 tgaactactt gttaggattg atgatgtttt agatgacaaa aagaaagctg atttattggc
    29461 ttacattgga acttattgtc gtgtgaaaca actcctcaaa cctgaagtta cggtgaccat
    29521 tacgttggaa ggactgtctc atgtctgatg ctagtttgaa aacttaccaa aaacaatggg
    29581 cttatcaaaa gtattgggtc atggcacact cacagcagca ttacaatgct ttaagagaat
    29641 tgtttaaagg aaatcagtgg tcagaagaaa aggtgttgac ttttcattgt ttgattgaag
    29701 aagcgcaagc cattcctccc acagtaaaaa gcttacgaac ggcatatcag catgtttggg
    29761 ggtattttaa aaaggtagcg agtcaggaag aaaaagacca tttcaaagat ttggatgctc
    29821 agttggaaac taaatctgag gagatgctat gctttttaca agagatgact gctcattatc
    29881 agccctctta tctgctatct tgccgtttga ttaccaaagg tccttaaatg ctaaacagaa
    29941 aagtagggat ttctgggaag ttatgctaag ctagtgatat aaataagggg gaatgagaga
    30001 tgtttttagc gcttaatgaa atgaaacaat ccaaattgcg gtatggtttg attgctggtt
    30061 tgctatgttt ggttgcctat ttgatgttct ttttgtcagg attggccttt ggtttgatgc
    30121 aggagaaccg ctcggcggtt gatctttgga aagctgacag tgttttacta gccaaggatg
    30181 ctgacgctac cttgacctta tcacaggtgt ccagagctca agaaaatcaa ataacagcag
    30241 acaaggtagc tcctcttgct caactcaata ccgtggcgtg gtcagttaaa aatcctaagg
    30301 atgccgacaa agttaaggtt agccttttcg ggattgattc taatagcttt attcgtccta
    30361 acattgtaaa aggtcgatta tttaagacta acaaagaggt tgttttggat caaagccttg
    30421 caaaagagga agcttttgcg attggcaagg acttttacac atcgagttct agtcaagcat
    30481 taactatcgt tggttatact caaaatgcta gatttagtgt tgcaccagtg gtttatatga
    30541 atttggaagc ttttgaaaca ttaaaatatg gagaaccact accaaaagat aagcaagttg
    30601 ttaatgcttt tatcactaaa ggaagtttaa cagattatcc taaaaaagac ttccaaaaat
    30661 tagatattaa aacctttatt actaaattac ctggttatag cgctcaactt ttaacttttg
    30721 gctttatgat tagttttctt gtcattattt cagctattat tattggtatt tttatgtata
    30781 ttttgactat tcaaaaggca cctatttttg ggattatgaa agcgcaaggt atcgggaata
    30841 taacgattgc acaagcagtt ctgctgcaaa ccttcttgtt aagtgcttta ggaagcggtt
    30901 tagggttatt gggaacttgg ttgacgtctt tagtgctccc tgaagcagtt cccttccaaa
    30961 gtaattggct agtttactta gcgatattag tcagtatggt ttgttttgct ttgttaggaa
    31021 ccttattttc tgtttttagc attgtacgaa ttgatccttt gaaagcaatt ggataggagg
    31081 tagtgatgtc ggttttaaca tttaaacaag tgaccaaaac atttcaagat ggtcatcacg
    31141 aaatcaacgc attaaaggca actgactttt ccattgaagc tggagaattt gtggctatta
    31201 ttggaccatc aggttctgga aaatcaacct ttttgaccat tgctggtggc ttacagaccc
    31261 caagctctgg tcagctaatc attgatggca ctgattatac ccatttatca gaaaaagagc
    31321 gctcacgctt gcgcttcaaa tccgttggtt ttatcttaca agcttccaat ctgatacctt
    31381 ttttaacggt ccagcagcag ttggaattgg tcgatcattt gacaggaagc aaagaaaaag
    31441 ccaaagccaa tcagttattt gacgatttag gcattacagg gctaaaacat cagttacctc
    31501 aagaattgtc cggcggagaa aggcaaagag cggctattgc ccgtgctctt taccatgatc
    31561 cggcactgat attggcagac gaacctactg caagtttgga tactgaaaaa gcctatgaag
    31621 tggtcaaact gttggctaag gaaagtaaag aaaaaaacaa ggccattatt atggtcactc
    31681 atgatgatcg gatgctaaaa tattgtgaca aagtctatca gatgcaagat ggagagttac
    31741 gtcaagagag atagtagact ggtaagagtt tatgatatta gaagaaaaaa ccaaacaagc
    31801 acagcacttg tctggttttt ttctaagtgt gactattatc aatacgtcac catttcccta
    31861 aagcttacta tacgggatgc taaaggtatc accatgctca aagtcgccat attggtaacc
    31921 tcggtcaaac caacgttggc gttgcttaga agttccgtgg gtaaaactat caggaacggc
    31981 tctgccatag gtttcttctt gcagagtatc atccccaact gcgtgagctg ctgccattgc
    32041 ttcctcaata tcaccttttt ccaaaaggcc ttgcccttga acataattag cccaggcacc
    32101 agcatagtaa ccagcttgta attccaactt gacgttgagc tgattggctt tagcctttga
    32161 ttttccttgt ctagcgctag cgtaattatc cataattccc aattcatttt ggatgtggtg
    32221 gccaacttca tgagcaatca cataggccat agcgaaatca ccttttgcgc cgtacttggt
    32281 tgatagttca ttataaaaag aaatatctaa atacactttt tgatcgcctg ggcaatagaa
    32341 aggaccagaa gaggcttgcc ccctgccaca agcggtttga gttgctccag tatatagaac
    32401 taatgttggt ttatgataag ttaacccttt ctcacgaaat gtcttagtcc aatagtcctc
    32461 ggtagaggcg aagaccttac tgacaaaaga aacctgttct tgactagcct tgtcaccatt
    32521 tgtacgcgtt acttggcttg attgataggc attgttgttg gtagaagaag gcttgcctcc
    32581 taaaacacca gataggccac ctcctcccat aactaggaga aggagaagaa taaccagctt
    32641 ggttttccaa cctcctcgtg aaaagagtaa ttgaagcagg agaccgcccc ctaggccgcc
    32701 gcccccaaaa gaaccagacg attgaccacg tctatcttca acctgttgac tttctctcaa
    32761 atcatctgtt ttcataagtt tctcccatct atttcttgat tttattataa aataattcta
    32821 ttagaattgc tatttttatg atgagattat aactaaaaat aggaaaagca ataggtattt
    32881 gctataatat aacaagggta gattcagttt gtataaagga gtcatatgaa attaatttac
    32941 acagagatga gttactcgat gacagagatt ttggtgaatg aagcacgaaa agctgctgac
    33001 caaggttatc gagtgttcta tattgctcca aattctcttt catttgaaaa ggaaagagaa
    33061 gtcttaacct tattgcctga acgagggact ttttcgataa tagttacccg gttcgttcaa
    33121 atgtcaaggt attttacagt tgagagctct ccttctaagc aacatctaga tgacacgact
    33181 ttggctatga ttttttatcg ggccttgatg caattaaaac cagaagattt gccgagttat
    33241 ggtcgtttgc aaaataattc ggtttttatt gaacaactag ttgagttata taaggaatta
    33301 aaaaacgcac aattaagcgt acatgattta acaggattag accatcctca aaaacaagaa
    33361 gatcttatta aaattattga gcttgcagag acgatcatga ttcagcaaga ttataatcaa
    33421 gatagtcctc tacaatcttt tgcaagagca attaagttag gacttttaaa taaccaacta
    33481 tcaaaaacag ttgttgttat tgatggtttt tcacgttttt cagctgaaga ggattattta
    33541 ttatcacttt taaataacaa ctgtcaagag gtcatcattg gcagttatgt gagtcaaaaa
    33601 gcttatcaaa aatcttttat taagggaaat atctatgagg ctagccttca ttttttgcag
    33661 gatttggctc aaaaatacca tatcaagccg gtatttgcga cctctaatca agtgtttaaa
    33721 ccagcctttt cacggctaac acaattattt gaagcaactc atgatttttc acaagtagac
    33781 tggcaactcc aaaagaatga tcttgatcac tttagccttt ggcaatgtca tcatcaaaaa
    33841 gaggaaattg aacatgtagc aaaatccatt cggcaaaagc tatatgaagg ttaccgttat
    33901 aaggatatct tagtgttgct aggagatatg gatgcttatc aattacaaat tgggcctatc
    33961 tttgataagt ttgaaatccc ctactattta ggaaaagcag agcctatggc tgcccatcca
    34021 ttagtccaat ttatagaatc gctcgaacga agtcagcgct acaattggcg tcgtgaagac
    34081 attttaaaca tgttaaaatc aggacttttt ggttgttttg atgatagtga tattgatcgc
    34141 tttgaggaat atactcagtt tgcagatatt aaagggttta ctaaattttc aaagcctttt
    34201 accattaact cttctaggca gtatcctctt gactttttaa atgaaatgag acaagacatc
    34261 gttttacctt tgcaagaatt gtttaagagt caaaaacaac ttggtgcttc acttgttgac
    34321 aaattaatac tttttttaaa aaagattaga ttagctgaga atatgcaagg tttagcacag
    34381 tcccaattag aggtggaaaa aaacgaagaa gtttggaaaa ggtttacaga tattttgact
    34441 tcttttcatc atatctttgg ccaagaaaaa ttacggctat cagattgcct tgctttaatc
    34501 aaaacgggaa tgaaatcagc tcagtatcgt gttgttccag cgacattaga tgttgtcact
    34561 attaaatctt atgaccttgt tcaaccacat tcaaaacctt tcgtttatgc aattggtcta
    34621 actcaatcac attttcctaa gcaaattcac cattcaggac tactttctga tcaagagcgt
    34681 gctagaatta atgaaataag aaattatcgt cattttgata ttgctagtgc cgaaaatagt
    34741 aaaaaaaacc atcaaactgc gttatctctg tttaatgctg ctactaaaga gttagttctt
    34801 agtgttccaa cggtaatcaa cgagacattc gatgatctat ctccttatct taaagaatta
    34861 ataagctttg ggctacctct tttggataaa ggcaaaaact atctatctta tgataatagc
    34921 gatattggta actataaagc tctcttgtca caaattattg ctattaaccg acaagatctt
    34981 atagaaatgt cagatcaaga taagatgttt tggactgttg tcttacgtta tctcaggaaa
    35041 cagttaagaa agcaacagct agagttacct acttcagatt atcgtttatc aacaaagcct
    35101 ttgtctaaag aagttatcga ggtatgtttt ccaaagggaa tccctttaaa gctatctgca
    35161 actgctttaa ccgtttttta taataatcag tacaactatt ttttgaaata tgttttgaat
    35221 ttaaacaaaa cagaatccat tcatccagat tccagaattc atggtcaata cttgcatcgt
    35281 gtctttgagc ggttaatgaa agatcacacg caagaaccgt ttgataataa gttaaaacaa
    35341 gcaatctacc ataccaatca agaaagtttt tttcagcagg tttaccaaga taatgccgag
    35401 gctgagtaca gtttagctat actagaagat attgttagat caacagcacc tatcttgcaa
    35461 cttaaccaaa acataaaggt cattgatcaa gaaaagaact ttcatctgga tatgggaaat
    35521 gagatattag tccacgggat cattgatcgt attgaccagc tgagcgacgg tagcttgggc
    35581 attgttgact ataaatcaag cgcgaatcaa tttgatattg ggacctttta taatgggttg
    35641 agtccacaac tagtgactta cctcgcagcc ttaaaacaga tcgcaccgca cgatataaac
    35701 caattatttg gggctatgta ccttcatttg caagatccta aattggatct agtaacattt
    35761 aaacaaattg ataacacatt agtggagagt atctataaag cgttgaccta taaaggtatt
    35821 ttttcagaag tcgaaaaaga gcatctatct actggtgctt accaaaccaa aaatgctctt
    35881 tattccaatg acgaattgga aacactttta aattataaca agtacctcta tcttaaagct
    35941 gctaaacaca ttaaaaaggg acattttttg attaatcctt atacaagtga tggtaagaca
    36001 gttcaaggag atcaattaaa agccattacc cgttttgaag cagatcttga catgggacag
    36061 gcaaggcgac tagtgactct ccctgctaag gagaaaaaag agtgcttttt aacattaatg
    36121 agaaaggaga gccacttgtg atttcttttg ccccattttt aagccccgaa gctattaaac
    36181 atttacaaga aaacgaaagg tacagtgatc agtctcaaaa acgcacagct caacaaattg
    36241 aagcaattta tactagtggc caaaatatac ttgtatcagc ttctgctggt tcaggaaaaa
    36301 cctttgtaat ggtcgaacgc atacttgata aaattttgag aggtgtttca attgatcggc
    36361 tttttatctc aacctttact gttaaagcag ctacagaact gcgtgaacgg attgaaaaca
    36421 aattatactc acaaattgct caaactacag attttcaaat gaaagtttat ttaacagaac
    36481 aattgcaatc tctttgtcaa gctgatattg gtactatgga tgcttttgca cagaaagtag
    36541 taagtcgcta tggttatagc attggcattt catcccaatt tcgtatcatg caggataaag
    36601 cagaacaaga tgttttaaag caagaggtgt ttagcaaact ctttagtgag tttatgaatc
    36661 aaaaagaggc accggcgttt agggctcttg tgaaaaattt ttctggtaac tgtaaagaca
    36721 cttcagcttt tagagagtta gtttatactt gttattcttt tagccaatcg acagaaaatc
    36781 caaaaatatg gttgcaagaa aattttctaa gcgctgctaa aacttaccaa agacttgaag
    36841 atatcccgga tcatgatatt gaactcttac ttttggcaat gcaagacact gcaaatcagc
    36901 taagagatgt gactgatatg gaagattatg ggcagctgac taaggcaggt agccgatctg
    36961 ctaaatacac taaacactta acgatcatag aaaagttgtc tgattgggtg cgtgatttta
    37021 aatgtttgta tggaaaagcc ggattggatc ggttgatcag agatgtgaca gaccttatac
    37081 catctgggaa tgatgttaca gtctcgaagg taaaataccc tgtttttaag accttgcatc
    37141 aaaaattaaa acaatttagg catttagaaa caattttaat gtatcagaaa gactgttttc
    37201 ccttattgga acagttacaa gattttgtgc ttgcgttttc agaagcttat ttagctgtca
    37261 aaatacaaga aagcgctttt gaattttcag atattgcaca ctttgcaatc aaaattttag
    37321 aggaaaatac ggatattcgc caatcctatc agcaacacta tcatgaggtg atggttgatg
    37381 aatatcaaga taacaatcat atgcaagagc gactcctgac cttactatcg aacggtcata
    37441 atcgctttat ggtaggagat atcaaacaat cgatctatcg atttcggcaa gccgatcctc
    37501 agatttttaa tcaaaagttt agagactatc aaaaaaaacc tgagcagggg aaagtgattt
    37561 tactcaaaga aaactttcgt agccaatcag aggtgttaaa tgtcagcaac gctgttttta
    37621 gtcacttaat ggacgaatca gtaggaaacg tcttatatga tgagcaacat cagttaatag
    37681 caggtagtca tgctcaaaca gtcccctatc tagaccgtcg tgctcagtta ttgctatata
    37741 atagcgataa agatgatggc aacgcccctt cagatagtga gggtatttca tttagtgagg
    37801 ttacaattgt tgccaaagaa attattaagc ttcacaatga taagggtgtc ccttttgaag
    37861 acattacgtt actcgtttct tcaagaacaa gaaatgatat catttctcat acattcaatc
    37921 aatatggtat tcctatagta acagatggtg ggcagcaaaa ctatcttaaa tctgttgaag
    37981 tgatggttat gttagataca ttacgcacca ttaataaccc aagaaatgat tatgcccttg
    38041 tggctttact gcgctcaccg atgtttgcct ttgatgagga tgatttagca agaatagcac
    38101 ttcaaaaaga caatgagcta gataaagatt gcctatatga caagatacaa agggctgtga
    38161 ttggaagagg tgctcatcct gaattgattc acgatacctt gcttggcaag ttaaatgttt
    38221 ttttaaagac gttgaaaagc tggcgtcgat acgctaagct agggtcgttg tatgacttga
    38281 tttggaaaat tttcaatgat cgtttttatt ttgattttgt agctagtcaa gcaaaagcag
    38341 aacaagcaca agctaatcta tacgcattag ctctacgtgc taatcagttt gaaaaatcgg
    38401 gctataaagg gctgtaccgt tttattaaaa tgattgataa ggtacttgag acgcaaaatg
    38461 acttagcaga tgtggaagtg gctgctccta aacaagctgt taatttaatg accattcaca
    38521 agtctaaagg tttacaattt ccgtatgtat ttatccttaa ttgtgacaag cgcttctcaa
    38581 tgacagatat tcataaatca tttattctga atcggcagca cggtatcggt atcaagtacc
    38641 ttgcagatat caaaggttta cttggtgaaa caacactcaa ttctgttaaa gtaagcatgg
    38701 aaaccttacc ttatcaattg aacaaacaag agttacgctt agcaacttta tcagaacaaa
    38761 tgcgcttact gtatgttgct atgacacgag ctgaaaaaaa agtttatttt attggtaaag
    38821 ctagtaagag caaaagtcaa gatatcacag atcctaaaaa gttaggcaaa cttttgccgc
    38881 tggctttacg agaacagtta ttgacattcc aagattggct attagcaata gcagatatat
    38941 tttcaactga agatctttat tttgatgttc gctttattga agatagtgat ttgacacaag
    39001 agtcagtcgg acgacttcag ataccacagt tattaaatgc agatgatctt aaagataatc
    39061 gtcaatcaga aacaattgca cgggctttag atatgttaga agcagtgtct caattgaatg
    39121 ccaattatga agcagctatt catttgccaa cagttcgaac gcctagccaa cttaaggcag
    39181 cttacgagcc tttattagaa cccattggtg tagatattat agagaaatct tctcgatcgc
    39241 tatctgattt tactttgcca catttttcaa aaaaagcaaa agttgaagca agtcatattg
    39301 gatcagctct tcatcagttg atgcaggtgc tccctttgtc aaaaccgata aatcaacaaa
    39361 cgcttttaga cgctttaaga ggaattgata gtaacgaaga ggtaaaaaca gctcttgatc
    39421 tcaaaaaaat agagtcgttc ttttgtgata caagcctagg ccaatttttt cagacttacc
    39481 aaaaacactt gtatcgagaa gcgccatttg ctattttaaa agttgaccct attagtcaag
    39541 aagaatatgt cctacgtggt attatagatg cctacttttt gtttgatgat catattgtat
    39601 tagtggacta taaaaccgat aaatacaagc agcccattga gttaaaaaag cgttaccaac
    39661 aacagttgga gttatatgca gaagctctca ctcaaacgta taaacttcct gtgactaagc
    39721 gctatcttgt tttaatggga ggtggaaagc cagaaattgt cgaagtttaa ggttgttgtg
    39781 acacaagggt attttgcaaa tgataatagt agagttgagg attttacgaa atgcttgaaa
    39841 agctattgac ctttgaataa taatacaata taataagttt tattagcgaa aaaaggaata
    39901 aatatactat gaattttaaa aaaataagat ttggtttttt gctttgcctc ctactttatc
    39961 ctttagcagc ttgtaacaag tctgaacaac ttaatcacta cgaaagaatt aaaaaaacaa
    40021 gaaaattagt cgttgctgta agccctgatt atgctccttt tgaatttaaa gctttagtta
    40081 atggaaaaga tactattgtt ggagcagatg ttcaattagc tcaggctatt gctgatgaat
    40141 tagacgttga tcttgagctt tcaccaatga gttttgataa tgttttgtct agtttacaga
    40201 ctggtaaagc tgatcttgct atttcaggaa tctcacatac taaagaaaga gctaaagtat
    40261 atgatttttc aattccttac tatcaggcag aaaacgctat agtgatgaga gcatctgatg
    40321 ctaaagtgac caaaaatatt agtgacctaa acggtaagaa agtagccgtt caaaaaggta
    40381 gtatcgagga aggtttagtt aaaatacaat taccaaaggc caatctgatt tctttgactg
    40441 ctatgggaga agccattaat gaactaaaag caggacaagt ctatgcagtt accttagaaa
    40501 cacctgtagc tgctggtttt ttagcccaac ataaggatct ggctttagca ccctttagct
    40561 taaaaaccag tgatggagat gccaaagcag tggcccttcc taaaaatagt ggtgacttaa
    40621 ccaaagccgt taataaggtt attgctaagt tagatgagca agaacggtac aagtcattta
    40681 ttgcagagac aatagcacta acgaaaaata ctatgaagta ataaggttaa taaaaacttt
    40741 attagtatcc gttggaaaag tgtttggaat aaacaataaa agaggtttga ctttttttaa
    40801 aaaataatgt aatataattg ggaacgtgaa aatgttacga tatcttgagg aggtgaaaca
    40861 catgtcaaaa acagtagtac gtaagaatga atctcttgac gatgctcttc gtcgcttcaa
    40921 acgttctgtt actaaagctg gtactcttca agaatcacgt aaacgtgaat tctacgaaaa
    40981 accttctgta aaacgtaaac gtaaatcaga agcagctcgc aaacgtaaaa aattctaatg
    41041 gtaaaaaata aaaacagttc tcacaattag aactgttttt attttttatc cagaagaagc
    41101 aagggagctt ttttgatatc aaaaaaagca gttagacatg cctaactgct ttatcaaaaa
    41161 tcgccttatt tttgagccaa caaatcacgg atttctgtca ataattcttc ttgagtagga
    41221 gctacagctt ctttttcttt tttaggcata gctttttcag cggcttttac aacaaagaaa
    41281 agactggtac cgatgataag aaaattaata acggctccta aaaagctacc atatttaaca
    41341 ccattccatg acaattgagt gatattttca acatttgcag ctttcagagc tgggtttaaa
    41401 ataagcggtg tgataatatc gttcacaaaa gaagtgacaa tagcaccaaa agctcccccg
    41461 atgataactg ctacagcaag ttcaataatg tttcctctaa acaaaaatgc ttttaattct
    41521 ttaaccatta aatattcccc cttttaatat ctctaagtta agcatagcat aattagtaaa
    41581 caaaatccaa tggaatcact tcagttttta aatttacaaa aaagagtttc ggtggtataa
    41641 taaaacgtaa aactaaaatg ggatttttat ggggaggtga cgatttggca attgacaaag
    41701 aaatgatttt ccaagtaaaa aatagcgtta atattgtcga tgtcattgga gaagtggtca
    41761 aactttcccg atcagggcgg cattatctcg ggctttgccc atttcataag gaaaagacac
    41821 cctcttttaa tgttgttgaa gacagacaat tttttcactg ctttggctgt ggaaaatcag
    41881 gggatgtttt taaatttatt gaggaatacc gccaagtccc cttcttagaa agtgttcaga
    41941 ttattgccga taagactggt atgtcgctta atatatcgtc aagtcaggca gtacttgcta
    42001 gccaacacaa gcaccctaat cacgctttga tgacacttca tgaggatgct gctaaatttt
    42061 accatgcagt tttgatgacc actaccattg gtcaagaagc taggaagtac ctttaccaga
    42121 gaggcttgga tgaccaatta attgagcatt tcaatattgg tttagcccca gatgagtcag
    42181 attatcttta tcaagctctt tctaaaaaat acgaggaagg tcaattggtt gcttcaggat
    42241 tgtttaactt gtccgatcaa tctaatacca tttacgacgc ctttcgaaat cgtatcatgt
    42301 ttcccttatc agatgaccga gggcatatta ttgccttttc aggacgtatc tggacggcag
    42361 ctgatacaga aaagagacag gccaagtata aaaattcaag aggaacagtt ctttttaaca
    42421 aatcttatga attgtatcat ctggacaagg caaggcctgt tattgccaaa acccatgaag
    42481 tatttctaat ggaagggttt atggacgtga ttgccgctta ccgttccggc tatgaaaatg
    42541 ctgttgcttc aatggggacg gcattgactc aagaacatgt caatcacctt aagcaagtca
    42601 ctaaaaaagt tgttttgatt tatgatggtg acgatgctgg acaacatgct attgcaaaat
    42661 cactagaatt gcttaaagat tttgttgtcg aaattgtcag aatccccaat aaaatggatc
    42721 ctgacgaatt tgtacaacgg cattccccag aagcatttgc agatttgctt aagcagtcac
    42781 ggatcagtag tgttgaattt tttattgatt acctaaaacc tactaatgta gacaatttgc
    42841 aatcacaaat tgtttatgtg gagaaaatgg caccattgat tgctcaatca ccatccatca
    42901 cagctcaaca ttcgtatatt aacaagattg ctgatttgtt gccaaacttt gactattttc
    42961 aagtagaaca atcagtaaat gcattaagga ttcaagatag gcaaaagcgt caaggtcaaa
    43021 tagctcaagc tgtcagcaat cttgtgacct taccaatgcc aaaaagtttg acagctattg
    43081 ctaagacaga aagtcatctc atgcatcggc tcttacatca tgactattta ttaaatgaat
    43141 ttcgacatcg tgatgatttt tattttgata cctctacctt agaattactt tatcaacggc
    43201 tgaagcaaca aggacacatt acatcttatg atttgtcaga gatgtcagag gaagttaacc
    43261 gtgcttatta taatgtttta gaagaaaacc ttcccaaaga agtagctctt ggtgagattg
    43321 atgatatttt atccaaacgt gccaaacttt tagcagagcg cgatcttcac aaacaaggga
    43381 aaaaagttag agaatctagt aataaaggcg atcatcaagc ggctctagaa gtactagaac
    43441 attttattgc gcagaaacga aaaatggaat agaggaaatt atgacaaaac aaaaagaaat
    43501 aacaactttt aacgttcaag ttgcggagtt tattcgccat cacaaaaaag aaggaacagc
    43561 gattgatgat gacgtgaccg aaaaacttgt cattccattt gctttggatg ctgatcagat
    43621 tgatgactta cttgagcggt taacagatgg tggtatctcg attacggata aagaaggtaa
    43681 cccatcatca aaatacattg ttgaagaacc aaaaccagaa gaattaactg atgaagaatt
    43741 aattggtagt aattcagcta aagtaaacga ccctgtccgc atgtacctca aagaaattgg
    43801 tgtggtaccg cttttaacaa gtgaagagga aaaagaattg gctgttgcgg ttgccaaggg
    43861 agatttaatg gctaaacaac gtttagcgga agcaaacctt cgtcttgttg tctcaattgc
    43921 aaaacgttat gttggacgtg gaatgcagtt tcttgattta attcaagaag gtaacatggg
    43981 actcatgaaa gctgttgata aatttgatta ttcaaaagga ttcaaattct caacttatgc
    44041 aacatggtgg attcgtcaag ctataacacg cgcaattgca gatcaagcac gtacgattcg
    44101 tatccctgtt catatggttg aaacgattaa taaattagtc cgtgaacaac gtaaccttct
    44161 tcaagaactt ggtcaagatc caacgccaga acaaatcgca gaacgtatgg aaatgactcc
    44221 agacaaggtt cgtgaaattc taaaaattgc tcaagaacct gtttctttag aaacaccaat
    44281 tggggaagaa gatgatagtc acttaggtga ttttatcgaa gatgaagtta ttgaaaatcc
    44341 agtagattat acgacgcgtg ttgttcttcg tgagcaattg gatgaagttt tagatacgct
    44401 tactgaccgt gaagagaacg ttcttcgcct acgctttggc cttgacgatg gtaaaatgcg
    44461 tacgttagag gacgtaggta aagtctttaa tgttactcgt gagcgcattc gacagattga
    44521 agctaaagcc cttagaaaac ttcgccatcc tagtcgtagt aaacaattaa gagactttat
    44581 agaggactaa aatcgtccag tggacgattt taggtcgttc ctttgaaata agaaaggagc
    44641 gaaaatccca agtggcactt atcagcggta cacctacaaa ttagaaaacg gaccgaatgt
    44701 ggtgggtatt tttaagggta gacttgatat cttaaacaag cccagagggc aattcctcta
    44761 aataggcaaa gctttagtgg tttttttact tatctacgac atattcaaaa aatgaaagga
    44821 aagccatgtc tgatacacca aaatatacac aagatcaggt gatagctatc aagaatagaa
    44881 ttcttgaagc tttagaaact gttattgatc ccgagctagg tattgatgtt gttaatctag
    44941 gcttgattta tgaaattcgg tttaatgata acggttatac agagattgat atgacactca
    45001 caacaatggg ttgtcctttg gcagacttgt tgacagatta catccatgat gccctgcaag
    45061 atgtgccaga agtcactaag actgaggtca aattagtctg gtaccctgct tggacggttg
    45121 ataaaatgag ccgctatgct aggattgcgc tgggtattcg ctaatcattg atagtaaagg
    45181 gatgaaatat tccctttttt gatgtagaat aaaaggaaat acaggtgaaa gcctttggtt
    45241 aatgttagag aacactaaga tactgagaaa agtgttctac ctatggcaaa aaggagaact
    45301 gatgatttta attacaggaa gcaatggtca attagggaca gaacttcgat acttattaga
    45361 tgaacgaggt gttgattatg tagccgttga tgtcgcagaa atggacatca caaatgaaga
    45421 caaagtcgaa gctgtttttg cgcaggtcaa gccaacattg gtctatcatt gtgctgctta
    45481 tacggcagtt gatgcagcag aagacgaagg aaaagccttg aatgaggcta ttaatgtaac
    45541 aggctcagaa aatattgcca aggcttgtgg aaaatatggg gctacccttg tttacatttc
    45601 aacagactac gtatttgatg gcaataaacc agtcggtcaa gaatgggtag aaacagatcg
    45661 tccagaccct aagacagaat atggccgtac aaaacgttta ggagaactag ctgttgaacg
    45721 atacgcagag catttttata ttatccgtac tgcttgggta tttggaaatt atggtaaaaa
    45781 ctttgtcttt accatggaac agttagcgga aaatcactcc cgtttgactg ttgtcaatga
    45841 ccaacacggt cggccaacgt ggacaagaac cttggcagaa ttcatgtgtt atttgacaga
    45901 gaatcaaaaa gcctttggtt actatcactt gtcaaatgat gctaaggaag acaccacttg
    45961 gtatgatttt gccaaagaaa tcttaaaaga caaggctgtt gaagtggtgc cagttgattc
    46021 atcagctttc ccagcaaaag ccaaacgtcc tttaaattca accatgaatc ttgataaggc
    46081 aaaagcaaca gggtttgtta ttccaacatg gcaagaagcc ttaaaggcat tttaccaaca
    46141 aggactgaaa aagtaagtat tctaaaaaga gttggctttc taaggccaac tctttttcat
    46201 gggtttaagg tcgcattagc cttctaattg tggtataata tcactgatta tattttagaa
    46261 tggggtagta tgcaatgcag gatgttttta tcattggtag cagagggtta ccagcgaaat
    46321 acggtggctt tgaaaccttt gtcgaagagt tgattagtca tcaatcatct aaaaacattc
    46381 gttatcacgt tgcttgttta agcgatacga agcataaggt tcattttgat tataaggggg
    46441 cagattgctt ttaccttaat cccccaaaac ttggtcctgc tagagttatt gcttatgata
    46501 tgatggcaat tacctatgcc ctgtcttata gcgaccaaca ccagattcag aaccctattt
    46561 tttatgtgtt gggcaatact gtaggcgctt ttattgcgcc atttgtgaag cagattcaca
    46621 atcgaggtgg acgctttttt atcaatccag acgggttaga gtggaaacgg tctaaatggt
    46681 caaaaccagt gcaggcctac ctgaagtttt ccgaaaagca aatgactaga caggctgact
    46741 tggtcatttc agataatatt ggcattgacc gctaccttaa acaggtttat ccttggtcta
    46801 aaacatgttt tattgcttat ggaacgcaga cacaaccttc acgtttgaca acagcagata
    46861 gcaaggtcag agcttatttt caaacctttg atattagaga aaaggattac tatctcattt
    46921 taggacgctt tgttcctgaa aataattacg aaactgctat taaagaattt atggcttcct
    46981 caactaagcg tgatttagtg attatttgta atcatgaggg caatgcttac tttaagcaat
    47041 tacttgctga gacagagtgt gataaagacc cacgcattaa atttgttggt accctttatg
    47101 acaaagaact attagcctac attcgagaac aggcttatgc ctatatccat ggtcatgagg
    47161 taggagggac taatccaggc cttctagaag cactagccca taccaatctt aatttggttt
    47221 taggagttga ttttaaccag tcggtggcta agtctgctgc gctttattgg accaagcaaa
    47281 aagggcaatt agcagagctg attaaccaag ttgatgcagg ttttgatagt gatcgtctgg
    47341 gcaaagaagc caaagctatt attcaagaac attacacttg ggaaaaaatt gtaggggagt
    47401 acgaggcttt atttttaaat gaacattaat attttactat ccacctacaa tggagaacgc
    47461 ttcttagcag aacaaattca aagtatccaa aggcaaacag ttaacgactg gaccttattg
    47521 attagagatg atggttcaac tgatggcacc caggatatta ttcgcacatt tgtcaaggaa
    47581 gacaaacgaa ttcagtggat caatgagggg cagacagaaa atctgggagt tattaagaat
    47641 ttttacaccc tcttaaagca ccaaaaagca gatgtctatt ttttcagtga ccaagatgat
    47701 atatggttag acaataaact ggaagtgacc ttattggagg ctcaaaaaca tgaaatgaca
    47761 gctcctttat tggtttatac agacctcaaa gtggtaaccc aacatttagc tatttgccat
    47821 gacagtatga ttaagaccca atctggtcat gcaaacacaa gcctacttca agaattaacc
    47881 gaaaataccg taacaggcgg cacaatgatg attactcatg ctctggctga ggaatggacc
    47941 acttgtgacg gtttattgat gcatgactgg tatttagctt tactagcttc tgctactggg
    48001 aaattagttt accttgatat tccaacagaa ttataccgtc agcacgatgc taacgtgttg
    48061 ggagctagaa cttggtctaa acgcatgaaa aattggttaa acccccatca tttagtcaac
    48121 aaatattggt ggttgattac ttcaagccaa aaacaggctc aattactatt agatttacca
    48181 ttaaaaccaa atgaccatga attggtaacg gcctatgttt ctttattgga tatgcctttt
    48241 accaaacgct tagctacctt gaaaaggtac ggttttagaa aaaatcgcat ctttcatacc
    48301 tttatttttc gtagtttagt tgttacctta tttggttaca ggagaaagta agaatgaatt
    48361 ttttaacaaa gaaaaaccgt attttactga gagaaatggt aaaaacggat tttaaattac
    48421 gctatcaagg gagcgcaatt ggctatctat ggtctatctt aaaaccgctt atgatgttta
    48481 cgattatgta cttggtattt attcgttttc ttcgcctggg tggagatgta cctcattttc
    48541 cagtagcgct tttattggca aatgtcatct ggtctttttt ttcagaagca actagcatgg
    48601 gaatggtatc tattgtatct cggggagact tgttgcgaaa attgaacttt tctaagcaca
    48661 tcattgtttt ttcggcagtg ttaggagctt taattaattt tcttattaat ttggttgttg
    48721 ttttaatttt tgcgttgata aatggtgtga ctatatcagg gtatgcttat ctctctcttt
    48781 ttctttttat agaattagtt gttttagtgc ttggaattgc attgttattg tcgaatgtct
    48841 ttgtttatta tcgtgactta gctcaagtct gggaagtact attacaagca ggtatgtatg
    48901 ccactccaat catttatccg atcacttttg ttttagatag ccaccctttg gcggcaaagt
    48961 tgttgatgct aaatccagta gcacaaatga ttcaagattt tcgttattta ttgattgaca
    49021 gagccaacgt aacgatttgg cagatgtcaa ctaattggtt ttacattgtt attccatatt
    49081 tagtaccatt tgttatatta tttattggca tctttgtctt taagaaaaat gccgatagat
    49141 ttgcggagat tatttaatga ttaatagaga aattgcagta aaagtacagc atgttagtaa
    49201 aacatttaaa ctgcctacag aagcaactaa aagttttcgc acgactctgg ttaatcgcct
    49261 aagagggatt aaaggattta ctgaacaaca tgtgctaaaa gatattaact ttgatgttta
    49321 taaaggcgat ttttttggaa ttgttgggcg taacggctcg ggaaaatcaa cgctccttaa
    49381 aattatttcc cagatctatg ttccagaaaa aggacaggtt acagtagatg ggaagatggt
    49441 ttcttttata gagcttggag tgggattcaa tccagaatta acaggacgag aaaacgtcta
    49501 tatgaacggc gccatgctgg gatttaccaa agacgaagtt gatgatatgt acaatgatat
    49561 tgttgatttt gcagagttgc atcattttat gaatcaaaaa ttaaaaaatt attcttctgg
    49621 catgcaggta cgtttagcat tttcagtggc tattaaagcc caaggtgacg ttcttatttt
    49681 agatgaggtg cttgctgtag gagatgaagc ttttcagcga aaatgtaatg attattttat
    49741 ggaaagaaaa gacagtggta agacgactat tttagtgaca catgatatgg gagctgttaa
    49801 gaagtattgt aaccgtgcag ttcttattga agatggtctt gttaaagcat atggagaacc
    49861 atttgatgtt gctaatcagt atagtgtaga taatacagag acagctgagg atgcaatgaa
    49921 tgctgaaaaa atatctgtat ctgatattgc caaagatttg aaagtgtcat taatctcaaa
    49981 tccaagaata acaccaaatg acacaatcac atttgaagtt tcttatgaag ttttaaaaga
    50041 tgattttacc tacattgcct tttctttaac ggatattgat agaaacattt gggtttacaa
    50101 cgacaattct ttagattatc caacacaagg tataggtaga aaatgcattt cctaccaatg
    50161 tcaactatct caacttaatg atataaaact aaaattagaa gtaactgtcc gagataagaa
    50221 cggtcagatg ctactctttt caacagcaga acaatcaccc cagatagtga ttcaaagaaa
    50281 cgatattgat caagatgatc tgtcagctct agattcagca agtggcttgt atcaacgtaa
    50341 tgggaagtgg gtttttcatt aatgagtaat agctagaagg gaatttatgt ataaagtttc
    50401 aattatttgc accaattata acaaagctcc ttggatatct gatgcacttg acagtttttt
    50461 aagccaagtg acagattttg aagttgaaat tattgttatt gatgatgctt ctacagatga
    50521 ctcacgagag attttaaaga gttatcaaaa aaagtcttca ggaaaaatta aattactctt
    50581 taacgaaact aatattggaa taacaaagac ttggataaaa gcatgccttt atgcaaaagg
    50641 caaatatatt gctagatgtg atggtgatga ttactggacg gatagtttta aactccaaaa
    50701 acaagttgat gtcttagaag cttccaaacg gtcacgatgg tgtaatactg attttgactt
    50761 tgtaaatagt caaggcgact tattatatgc taatgctttt tcatctggtc atacaccttt
    50821 gacagacact tacgaaaaag ttttagcctt aaaagggatg acgatggcat cgacatggtt
    50881 agttgatgct gatttaatga gacaagtaaa ccaaaaaatc aatgtagata caccagacga
    50941 tacttttgat attcaactag agttatttca actgactcaa ctgacctata ttaaagactc
    51001 aacgacgatt tatcgcatga caaccgattc tgattcaaga cctactgata caccaaaaat
    51061 gattcatcgt attcaaaaac tacttgatac tcagttaaat tacttaaaaa agtataatca
    51121 ggtagataca aaagaagtgt ctgaactatt attacaacaa gatgctaagc aagaaatacg
    51181 aattcatgag ttgagttgct ttattcaaga attacaacaa actatcgtag ataaaacaaa
    51241 gcagcaagaa acacgtgaag tggagttgca aaatgtcata gaagaacaaa aaaatcaact
    51301 atctgaatta agacaacaat accatgccat tattaattca cgtcaatgga aatacacgtc
    51361 taagctcatt gcttttatta ggagaaaaaa atgaatcgta ttttattata tgttcacttc
    51421 aacaaataca ataaaataag tgcacatgtt tactatcaat tggaacaaat gagatcactg
    51481 ttttctaaga ttgtttttat ctcaaatagt aaagtgagtc atgaagattt aaaacgtctc
    51541 aaaaaccact gtcttattga tgagtttttg caacgcaaaa ataaaggttt tgatttttct
    51601 gcatggcacg atggcttgat tactatggga tttgacaagt tggaagagtt tgactcattg
    51661 acgattatga acgatacttg ttttggtcct atttgggaga tgggtcctta ttttgaaaat
    51721 tttgaagaaa aagaggcagt tgacttttgg ggaattacta ataatagagg tacaaaagct
    51781 tttaaagaac atgtccaaag ttattttatg acgtttaaaa atcaagtcat tcaaaacaaa
    51841 gtttttcaac aattttggca atcgataata gaatatgaaa acgttcaaga agtgattcag
    51901 cattacgaaa cgcaattaac atccattctc ttaaatgaag gctttagtta tcagacggtc
    51961 tttgatacta gaaaaactga gtcgtcattc atgccacatc cggatttttc atattataat
    52021 ccaacagcaa ttttaaaaca ccatgtgcct tttataaaag taaaagctat tgatgctaac
    52081 cagcatatcg ctccttactt actgaatctg atacgagaaa caaccaatta tcctatagat
    52141 cttattgttt cacatatgtc gcaaatctct ttgccagatg ctaagtacct tttatctcaa
    52201 aaatacctaa actgccaacg gttagcaaaa caaacttgtc aaaaggtagc tgttcattta
    52261 catgtttttt acgttgattt gctagatgaa tttttaacag ctttcgaaga ctggaacttc
    52321 cattatgatc tttttattac aacagatagt gatatcaaaa gaaaagagat caaagaaata
    52381 cttcaaagaa aaggtaaaac tgctgatata cgcgttacgg gaaatagagg aagagatatt
    52441 tatccaatgt tattactaaa agataaactt tctcaatatg attatattgg tcatttccat
    52501 acgaaaaaat caaaagaagc tgatttttgg gcaggagaat cttggcgaaa agaattgatt
    52561 gatatgctcg tgaaaccagc agatagtatt cttagcgctt ttgagacaaa tgatattggt
    52621 attataatcg cagatattcc aagttttttt agatttaata agattgtcaa tgcttggaat
    52681 gagcatttaa tcgctcaaga aatgatgtct ttgtggagaa aaatggatgt taaaaaacaa
    52741 attgattttc aagctatgga tacatttgtt atgagttatg gaacatttgt atggtttaaa
    52801 tacgatgctc taaaatcact ttttgattta gaattaactc aaaatgatat tccaagtgag
    52861 cctttaccac aaaactctat attacatgcg attgagcggt tacttgtcta tatagcgtgg
    52921 gggaattctt atgattttag gattgttaaa aatccctatg agttaacacc ttttattgac
    52981 aataaactgt taaatttacg tgaagatgaa ggagctcata cctacgttaa ctttaatcaa
    53041 atgggcggta tcaaaggagc attaaaatat attatcgttg gtcccgctaa agcaatgaag
    53101 tatatattct tgcgtttaat ggagaaactt aaatgattaa agacacattt ttaaaaacca
    53161 attggttaaa tattagccac catattaccc ttcttgtttt cggtttttat ttcagttttt
    53221 atagtttggc gaaagaacta gtaagctcca cggcacaacc ggtaaactat tatactcatt
    53281 tactaaatgt ttcttttgtg ggatatatta tatcactgat tggattatct tattatttga
    53341 gtcgccaagt tagtcgacag ctgtttttga aaactagttt tattgtgata tcttatctaa
    53401 ttgtcagcta ttgggtacaa ataacacagc acctgaatga taaacggttt gatatctggt
    53461 cattaactaa aaatcaattt tatcaatttc aagctctacc ttctttactc attattttag
    53521 tgatggccac tttaataaaa atattggtag catattttgc aatagaaaaa gatagatttg
    53581 ggctattatg ctatcaaggt aatacttttt ctgtagctct gattttagca gttgtgccaa
    53641 ttagtgacat acatctgtta aaactaataa gttctcgatt ttctgaatta gtaagagcag
    53701 gtaatagcca aattgcactg ttaaaaataa gtggactgtt gatagtttta cttgtcatat
    53761 ttgcaacaat catatacgtg gttttaaatg ctctaaaaca ccttaagtca aataaacctt
    53821 cattttcagt agcagctact actagtttgt ttttagcatt agtttttaac tatacgttcc
    53881 agtatggagt aaaaggtgat gaagcattgc taggatatta tgttttccct ggagctactc
    53941 tttttcagat agtagctatt acactagttg ctcttttagc atacgtgata acgaatagat
    54001 attggccaac taccttcttt ttgcttattc tgggaacaat tatttctgtt gttaatgatt
    54061 taaaagaatc aatgagaagc gagccgttat tagtaactga ttttgtttgg ttacaagaat
    54121 taggtttagt gacaagcttt gttaaaaaat cggtgattgt agaaatggtt gtaggacttg
    54181 ctatttgtat tgtggtggct tggtatctac atggccgagt tttagcaggg aaattattta
    54241 tgagccctgt caaacgggca agtgctgtat taggtttatt tattgtatct tgtagtatgt
    54301 taataccatt ttcttatgaa aaagaaggta aaatattatc tggtcttccg attatttcgg
    54361 ctttaaataa tgataatgat ataaactggt taggtttttc aacaaatgct aggtacaaat
    54421 ctttagcata tgtttggaca agacaggtga ccaagaaaat aatggaaaaa ccgacaaatt
    54481 atagccaaga aacaatagcg agtatcgctc agaagtacca aaaattagca gaagatatta
    54541 ataaagacag aaaaaataat attgctgacc aaacggttat ttatctttta agtgaaagtt
    54601 tgtcagatcc tgatagagta tcaaatgtta ctgttagcca cgatgtttta cctaatatca
    54661 aggcaatcaa aaatagcaca actgcgggac tcatgcagtc agactcctac gggggtggaa
    54721 ctgctaacat ggagtttcaa acgttaacaa gcttaccttt ttataatttt tcttcttcag
    54781 tatctgttct ttattcagaa gtctttccta aaatggccaa acctcatacg attagtgagt
    54841 tttaccaagg aaaaaatcgt attgcgatgc atcctgctag tgctaacaat tttaatagaa
    54901 aaacagttta tagtaattta ggtttttcca aattcttagc tctatcgggt tctaaggata
    54961 agtttaagaa cattgaaaat gtcggtttat tgactagcga taaaactgtc tataataata
    55021 ttttatcttt aattaatcct agtgaaagcc aatttttctc agttattaca atgcaaaatc
    55081 atattccttg gtcatccgat tatcctgaag aaattgttgc tgaaggaaaa aatttcacgg
    55141 aagaagaaaa tcacaaccta acaagttatg ctcggttatt atcgtttact gataaggaaa
    55201 caagagcatt tttagaaaaa ttaacacaaa ttaacaagcc tatcacagtg gtgttttacg
    55261 gagatcattt acccggttta tatcctgata gtgcttttaa caagcatatt gaaaataaat
    55321 accttactga ttattttatt tggagtaatg gtactaacga gaaaaaaaat catccgctta
    55381 tcaactcaag tgattttact gcagctttat ttgagcatac tgattcaaaa gtatcacctt
    55441 actatgcttt gttaacagag gtactgaata aagctagtgt cgataaatca ccagatagtc
    55501 ctgaagttaa agctattcag aatgatttaa aaaatatcca atacgatgtg actataggaa
    55561 aaggttacct tttgaaacac aaaacttttt ttaagatatc acgttaagaa aaatgctagg
    55621 ctgtccgagt atagacgagc atcaaggttt ggtaatttgc tcaaatgatt gtcaacagag
    55681 tgtctaggac caggtttaaa agattataat tcttaaggtc ttattcgttt ataaaaaatg
    55741 aatactcttt taaaatctta attgaaatga ataggagaag ttttcgtgaa aaagttaatc
    55801 attattcctg cttacaatga aagcagtaat attgtcaata ctatacgtac tattgaatca
    55861 gatgccccgg attttgacta tatcattatt gatgattgct caacggataa tacgttagca
    55921 atatgtcaaa aacaggggtt caatgttatt tctttgccca ttaacctggg aattggcggt
    55981 gcggtgcaaa ctggctatcg ttatgcacaa agatgtggat atgacgttgc agttcaagta
    56041 gatggagatg gtcagcacaa tccatgctat ttggaaaaaa tggttgaggt attagttcaa
    56101 tcttcagtaa atatggtaat tggatcacga tttatcacaa aagaagggtt tcagtcatca
    56161 tttgctcgac gtatcggtat aaagtatttt acttggctta ttgcgctact aacaggaaaa
    56221 aaaataacag atgcaacgtc aggtctaagg ttaattgacc gttcattgat tgaacgtttt
    56281 gctaatcatt atccagatga ttatcctgaa cctgaaacag ttgttgatgt attggttagt
    56341 cattttaaag tgaaagaaat tcctgttgta atgaatgagc gacaaggcgg tgtgtcatct
    56401 atctcgttga cgaaatcggt ctattatatg attaaagtga ctttagctat tttagttgtt
    56461 aggttgaaag gaaatcgtta aaatgacggt aacagccagt ttatttataa gttttattgt
    56521 attaaccttt gttttctttt tgattaactt aatcaaaaaa gacaaactag cgattaagta
    56581 ctctttattg tggtttattt tagctttatt aattttacta tttacgtggt tacctaacat
    56641 attaaataaa atgtctcact tcctgggtat tcattcacca accaatatgt tattcttttt
    56701 aggtttttgt ttgagtttag ctattatttt ttcactgact aataatattt cacttcaaaa
    56761 tgataaagta aaacgtctga cccaagaagt ggcccttatg aaaaaagaga aaaccaatga
    56821 ttaatccttc aaaacaaaac caaacgattt ttttatggaa tatgttagga agtttatcaa
    56881 cagctgtaat atcagttata ttacttatgg tggttactag gttactaact tcgtctgatt
    56941 cagatattta cgcctttgcc tattcttttg ctaatatgat ggtagttgtt ggactttttc
    57001 aggttcgtaa ttatcaagca acagatatta atgaaaaata ttcctttagt cagtacttag
    57061 tagcaagact gatgacttgt ttattaatgt tagctataac agtaatttat ttaacgttaa
    57121 ctaagacaga tagctacaag agtacaattg tctttctagt ctgtttctat agatcgacag
    57181 atgctttttc ggatttatat cagggaatgt tccaacaaca tgaacggctg gatattgcag
    57241 gtaaatcgct agcctacaga aatactctta tttttatggt gtacacagca ataatattat
    57301 attccaaaaa tcttacttta gcattagtag ctgtctgtat ag
//
LOCUS       DAUGOH010000008        53436 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUGOH010000008 DAUGOH010000000
VERSION     DAUGOH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53436
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.008"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            31..297
                     /locus_tag="VH957_000502"
     CDS             31..297
                     /locus_tag="VH957_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8558444.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSTP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            331..1065
                     /locus_tag="VH957_000503"
     CDS             331..1065
                     /locus_tag="VH957_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558445.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            1070..2698
                     /locus_tag="VH957_000504"
     CDS             1070..2698
                     /locus_tag="VH957_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558446.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMM
                     RQQALMIAIFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGTVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVVQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKVKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     EFMYRRDYRLLDLKWQDMTQLFTRGNGQWLTMGLIFGNLIVTGVVGFGAVIIANIIQQ
                     PLLISVLLSCLTLMVLGLAQLWIQKTFWKSLERL"
     gene            2763..3584
                     /gene="proB"
                     /locus_tag="VH957_000505"
     CDS             2763..3584
                     /gene="proB"
                     /locus_tag="VH957_000505"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEQ8558447.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKSPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            3577..4827
                     /locus_tag="VH957_000506"
     CDS             3577..4827
                     /locus_tag="VH957_000506"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEQ8558448.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNCFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAMAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDAFHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     HTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            4847..5062
                     /locus_tag="VH957_000507"
     CDS             4847..5062
                     /locus_tag="VH957_000507"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558449.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFVFLEMVC
                     WSAGSNVVSKFNQLLIDLQVTLQNCRR"
     gene            5105..5269
                     /locus_tag="VH957_000508"
     CDS             5105..5269
                     /locus_tag="VH957_000508"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558450.1"
                     /translation="MSWDKIFDIWLDNLLTDCCVIKEAKNLLQAVETLEAAAKSVLAK
                     LADSEQKEQD"
     gene            5293..6306
                     /gene="rsmH"
                     /locus_tag="VH957_000509"
     CDS             5293..6306
                     /gene="rsmH"
                     /locus_tag="VH957_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEQ8558451.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLQSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPTFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            6311..6634
                     /gene="ftsL"
                     /locus_tag="VH957_000510"
     CDS             6311..6634
                     /gene="ftsL"
                     /locus_tag="VH957_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEQ8558452.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            6638..8893
                     /locus_tag="VH957_000511"
     CDS             6638..8893
                     /locus_tag="VH957_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8558453.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGTGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            8895..9905
                     /locus_tag="VH957_000512"
     CDS             8895..9905
                     /locus_tag="VH957_000512"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEQ8558454.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGTMIGALLGFFL
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            10063..11406
                     /locus_tag="VH957_000513"
     CDS             10063..11406
                     /locus_tag="VH957_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8558455.1"
                     /translation="MSFKDYHFKQYIQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDETKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            11601..12404
                     /locus_tag="VH957_000514"
     CDS             11601..12404
                     /locus_tag="VH957_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8558456.1"
                     /translation="MTSVFLTSGWAFYDHLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKCLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            12404..13147
                     /locus_tag="VH957_000515"
     CDS             12404..13147
                     /locus_tag="VH957_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558457.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            13251..13475
                     /locus_tag="VH957_000516"
     CDS             13251..13475
                     /locus_tag="VH957_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEQ8558458.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            13539..14456
                     /gene="trxB"
                     /locus_tag="VH957_000517"
     CDS             13539..14456
                     /gene="trxB"
                     /locus_tag="VH957_000517"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEQ8558459.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            14625..16004
                     /locus_tag="VH957_000518"
     CDS             14625..16004
                     /locus_tag="VH957_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8558460.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            16175..17635
                     /locus_tag="VH957_000519"
     CDS             16175..17635
                     /locus_tag="VH957_000519"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEQ8558461.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAIIGGADATSNVRAGKRFGIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMALIDNIRKDTHGKSDLK"
     gene            17632..18456
                     /gene="nadE"
                     /locus_tag="VH957_000520"
     CDS             17632..18456
                     /gene="nadE"
                     /locus_tag="VH957_000520"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEQ8558462.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQAVALQQAGIEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALEVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            18641..19978
                     /gene="pepC"
                     /locus_tag="VH957_000521"
     CDS             18641..19978
                     /gene="pepC"
                     /locus_tag="VH957_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEQ8558463.1"
                     /translation="MSALTETFTEQLFAHYEASAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQY"
     gene            complement(20443..22608)
                     /locus_tag="VH957_000522"
     CDS             complement(20443..22608)
                     /locus_tag="VH957_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8558464.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(22595..23203)
                     /gene="recU"
                     /locus_tag="VH957_000523"
     CDS             complement(22595..23203)
                     /gene="recU"
                     /locus_tag="VH957_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEQ8558465.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            23284..23799
                     /locus_tag="VH957_000524"
     CDS             23284..23799
                     /locus_tag="VH957_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEQ8558466.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            23921..24247
                     /gene="gpsB"
                     /locus_tag="VH957_000525"
     CDS             23921..24247
                     /gene="gpsB"
                     /locus_tag="VH957_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEQ8558467.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRIAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            24261..24629
                     /gene="rnpB"
                     /locus_tag="VH957_000526"
     ncRNA           24261..24629
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VH957_000526"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            24692..25846
                     /locus_tag="VH957_000527"
     CDS             24692..25846
                     /locus_tag="VH957_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEQ8558468.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKINGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            25860..27329
                     /locus_tag="VH957_000528"
     CDS             25860..27329
                     /locus_tag="VH957_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558469.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQITKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(27474..27956)
                     /locus_tag="VH957_000529"
     CDS             complement(27474..27956)
                     /locus_tag="VH957_000529"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEQ8558470.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGTTWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(28030..29361)
                     /locus_tag="VH957_000530"
     CDS             complement(28030..29361)
                     /locus_tag="VH957_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEQ8558471.1"
                     /translation="MEIIGSLGVLVGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMD
                     PTKTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMAMG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIVIAFDLFS"
     gene            complement(29432..30211)
                     /locus_tag="VH957_000531"
     CDS             complement(29432..30211)
                     /locus_tag="VH957_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEQ8558472.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYIAQ"
     gene            complement(30244..30903)
                     /locus_tag="VH957_000532"
     CDS             complement(30244..30903)
                     /locus_tag="VH957_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8558473.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPSIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            complement(30905..31556)
                     /locus_tag="VH957_000533"
                     /pseudo
     CDS             complement(30905..31556)
                     /locus_tag="VH957_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
     gene            complement(31580..32767)
                     /locus_tag="VH957_000534"
     CDS             complement(31580..32767)
                     /locus_tag="VH957_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8558474.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALGNHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            32966..33862
                     /locus_tag="VH957_000535"
     CDS             32966..33862
                     /locus_tag="VH957_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8558475.1"
                     /translation="MDIKQIRYFIAIVENHFNLNQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNLKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQFKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            33992..35599
                     /locus_tag="VH957_000536"
     CDS             33992..35599
                     /locus_tag="VH957_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEQ8558476.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            35709..36344
                     /gene="gmk"
                     /locus_tag="VH957_000537"
     CDS             35709..36344
                     /gene="gmk"
                     /locus_tag="VH957_000537"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEQ8558477.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKKTFKAK"
     gene            36360..36677
                     /locus_tag="VH957_000538"
     CDS             36360..36677
                     /locus_tag="VH957_000538"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEQ8558478.1"
                     /translation="MMLKPSIDTLLDKVSSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            36742..39126
                     /locus_tag="VH957_000539"
     CDS             36742..39126
                     /locus_tag="VH957_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEQ8558479.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFIIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKAIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERQIDRSEPYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PIYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEAKILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            39188..40123
                     /locus_tag="VH957_000540"
     CDS             39188..40123
                     /locus_tag="VH957_000540"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEQ8558480.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSD
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            40113..41435
                     /gene="rsmB"
                     /locus_tag="VH957_000541"
     CDS             40113..41435
                     /gene="rsmB"
                     /locus_tag="VH957_000541"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEQ8558481.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRAVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            41473..42213
                     /locus_tag="VH957_000542"
     CDS             41473..42213
                     /locus_tag="VH957_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEQ8558482.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            42210..44108
                     /gene="pknB"
                     /locus_tag="VH957_000543"
     CDS             42210..44108
                     /gene="pknB"
                     /locus_tag="VH957_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEQ8558483.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSREHKIIFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGELSLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            44231..44923
                     /locus_tag="VH957_000544"
     CDS             44231..44923
                     /locus_tag="VH957_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEQ8558484.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            44920..45924
                     /locus_tag="VH957_000545"
     CDS             44920..45924
                     /locus_tag="VH957_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8558485.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            45917..46558
                     /locus_tag="VH957_000546"
     CDS             45917..46558
                     /locus_tag="VH957_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8558486.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            46595..47995
                     /locus_tag="VH957_000547"
     CDS             46595..47995
                     /locus_tag="VH957_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8558487.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPRLQEKADVITKKVEEDGILYALEELGLIDKELQFPQL
                     DLANHKGPKATIKTNHGDMTLVLFPEHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQYFIVQNSKVP
                     YAKKELERGGWPAPIAASYAENGGTPHLDRRHTVFGQLVNETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            47995..48372
                     /locus_tag="VH957_000548"
     CDS             47995..48372
                     /locus_tag="VH957_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8558488.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALDNGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKASLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(48390..49331)
                     /gene="cysK"
                     /locus_tag="VH957_000549"
     CDS             complement(48390..49331)
                     /gene="cysK"
                     /locus_tag="VH957_000549"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEQ8558489.1"
                     /translation="MTKIYKTITELVGQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETAIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARRTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIETK"
     gene            complement(49459..50091)
                     /locus_tag="VH957_000550"
     CDS             complement(49459..50091)
                     /locus_tag="VH957_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEQ8558490.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNSQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSSMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            50146..51471
                     /locus_tag="VH957_000551"
     CDS             50146..51471
                     /locus_tag="VH957_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8558491.1"
                     /translation="MESIENSYGRLLLESQLPDSARQLAQPLKSVVISRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLIYAIPPMHFPKGNYLVWSGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEGITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLAKKEIKEMNYKGYSHDLSTMSTN"
     gene            51443..52108
                     /locus_tag="VH957_000552"
     CDS             51443..52108
                     /locus_tag="VH957_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEQ8558492.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACQDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSLGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            52188..52736
                     /gene="raiA"
                     /locus_tag="VH957_000553"
     CDS             52188..52736
                     /gene="raiA"
                     /locus_tag="VH957_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEQ8558493.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDDATNILYRREDGNLGLIEAK"
BASE COUNT        16896 a         9416 c        11010 g        16114 t
ORIGIN      
        1 cgtaaaagta caaaaaataa aggagtataa atggaaaaga aacgacagcg cttatacgat
       61 gtgattagac aggcttatga ttatccagaa aaccgtgaaa atgtggcctt gtcgcagcta
      121 cttttagcag cttctaatag attaattaaa cacagtaccc cacttcttgt tgcctaccaa
      181 ctaaaccaag atgtggataa ttacttactt gataatgaca ttttacttcc aaaatcgctt
      241 tgccgtttta agcagtcatt ggaaaagtat attttagagg aagcctcatc agtctaggga
      301 gaaaaagaga agaaaaggaa aaaggatacc atgatagaat ttaaacatgt ttcaaagttg
      361 tatggcgaca aagaagctct cagcgattta aacgtcacca tcaatgacgg tgaaattttt
      421 ggccttatcg gacataatgg tgcaggtaaa accacgacca tcagcatttt gacttctatt
      481 atcgaagcga gttatggcga agtatttgtg gatggtcaac ttctgacaga aaatagagaa
      541 gctatcaaaa aacaaattgc ttatgtgcca gattctcctg atattttctt gaatctaact
      601 ccaaatgagt attggcaatt tttagccaaa atttatgggg tgtcagatga ggaccgagaa
      661 gaacggttag cacagctgac aacacttttt gaactgaagg aagaagttaa tcaaaccatt
      721 gatagtttct cacatgggat gcgccaaaaa gtgattgtga ttggtgctct tgtatcaaat
      781 cctaacatct ggattttgga tgaaccatta acaggtttgg atcctcaggc ttcttttgac
      841 cttaaagaaa tgatgaaagc tcatgcagct tctggacata cggtcttatt ttcgactcac
      901 gtgctatcag tcgctgagca gttatgtgat cgtatcggga ttctaaaaaa agggaaattg
      961 atttttgttg gaacgattga tgagttgaaa gaacaccatc ctgacaaaga cttggagagc
     1021 atctaccttg aactcgctgg gcgtaaggcg caagaagagg ggtgatggga tgaattggtc
     1081 tactatttgg gaacttatca agataaacat tctttattcc aatccacaaa gtttagctaa
     1141 cctcaaaaag cgtcaggaaa aacacccgaa agaaaacttc aaggcctata aaagcatgat
     1201 gaggcaacag gccttaatga ttgccatatt tttggtgatt taccttttta tgtttattgg
     1261 tgttgatttc agtcattatc caggactttt ctcctttgac gttgctatgt tttttatcat
     1321 gtcaaccttg acagccttta gctctcttta caccattttt tatgaaagta atgacctaaa
     1381 actttatatt cacttaccag taacgtcaga agaactctat attgcaaaaa ttgtctcatc
     1441 gctagggatg ggtactgtct ttttgatgcc ccttatctct cttctcttaa ttgcctattg
     1501 gcaactcttg ggaaatcctt tgtctatttt agtagctatc gtgctctttt tagtgttact
     1561 agtgagttct atggtattag ctatttatat caatgcttgg gtaggcaaaa tcattgtaag
     1621 aagtcgcaaa cgaaaactca tttcaactat catgatgttt gtctcaactt ttggcgcttt
     1681 cgtcttaatt tttgcgatta atattagtaa taacaagcgt acgatgacgg atggcgtatt
     1741 tactgattac ccaactattc cctatttcaa aggattctat gatgttgttc aggcaccgtt
     1801 ttctactgcg gccctcctta acttttggtt gccattgtta cttatcctag ctatggtata
     1861 tggtattgtc acaaaagtga tgccaactta ttatcgtgag gctttttata ttagtaacga
     1921 gaacaaagtc aagcaaacta aaaaaccagt taatcgtcct catcagaatc aatcactggc
     1981 gcagttgttg cgaaaacatc acctattaac gttacaaaat gcaactttac tgacacaaac
     2041 ctatctcatg cccctgatgt atgtgatgct ttttatcggt ccaagtttgt cacgtggcac
     2101 aggtttcttt aagcatattt ccccagatta ctttggggtg gccttattat ttggggtcag
     2161 tttgggtgtc atgtgtgcaa caccaaccag ctttattgga gtaggtattt cacttgaaaa
     2221 ggataacttt acctttatta aaagcttacc aataacgtta aaaaaattct tgctggataa
     2281 attttgcttg cttgtaggtc tgcaactgat tgtgcctatg gtgatttatc ttgtgtttgg
     2341 tctctttgtg ttgcacctgc atcctcttct aacgattgct ttttgtcttg gctacgccct
     2401 gtctctgatt gtgcaagggg agtttatgta tcgtcgtgac taccggcttc tggatttaaa
     2461 atggcaagac atgacacaac tctttaccag aggaaatggg cagtggctaa caatgggcct
     2521 tatctttggt aatttaatag tcacaggtgt agtaggtttt ggagctgtta tcattgccaa
     2581 tattatccaa caacctctgt tgattagtgt tctactgagt tgtctgacac taatggtttt
     2641 aggtcttgcg caattatgga ttcaaaaaac cttctggaaa agcttagaga ggctttaacg
     2701 aagagggatc attattcgga aaaacagtcc tctggggctg ttttttatgc tataatttgg
     2761 gtatgatgaa acgacaattt gaagatgtaa cacgtatcgt aattaaaatt ggcactagtt
     2821 cattagtgct accaacaggt aaaatcaatt tagaaaaaat cgaccaactg gcttttgtga
     2881 tttcaagttt gatgaataag ggcaaggaag ttattttagt atcatcggga gcgatgggat
     2941 ttggactaga tattttgaaa atggaaaaac gtccgaccaa tcttgctaaa caacaggcag
     3001 tttccagtgt tggtcaggtg gccatgatga gtctttattc acaaattttt gcacactacc
     3061 aaaccaacgt gtcgcaaatt ttattgacga gagatgttgt ggtttttcca gaaagtctag
     3121 ccaatgttac caatgctttt gaaagtctga ttagtttggg cattgtgccg attgttaatg
     3181 aaaacgatgc ggttagtgtg gatgaaatgg atcatgcgac taaatttgga gataatgacc
     3241 gtttatctgc tgtcgttgct ggtattacaa aagctgattt attaatcatg ttgtctgata
     3301 ttgatggcct ttttgataaa agccctacta tttatgagga tgcgcagcta cgcagccatg
     3361 ttgcggtcat tacgcaagaa atcattgcgt cagcaggtgg tgcgggcagt aagtttggca
     3421 caggtgggat gcttagcaaa attcagtctg ctcagatggt atttgaaaac aaaggacaga
     3481 tggtcttgat gaatggagct aatcccagag atattttaag agtgcttgaa gggcaaccac
     3541 taggcacctg gttcaagcag atagaagagg taacacatga ctgatatgag aaggttaggg
     3601 caaagggcaa aacaagctag tcttttaata gcacctttgt cgacgcaaat taaaaattgc
     3661 tttttaagca ccttagcaaa ggcattagtt gacgatacac agactctctt agccgctaac
     3721 caaaaagatt tagcgaatgc taaagaacat ggtatttctg acatcatgat ggatcgcttg
     3781 cgcttaactt cagaacggat taaagcgatg gcacagggag ttcaacaggt tgctgactta
     3841 gctgatccaa tcggacaagt cattaagggc tatactaacc tcgatggcct taaaatcctc
     3901 caaaagagag ttcctctagg ggtgattgcg atgatttttg agagtcgccc gaatgtttca
     3961 gtggatgctt ttagtctggc gttcaaaacc aataatgcca tcatcctaag gggaggaaaa
     4021 gatgcctttc actcaaataa agctttggtg aagttgatcc gacaaagtct ggaaaaatca
     4081 gggatcaccc cagatgctgt ccagctagtt gaggatccct cacatgctgt cgctgaagaa
     4141 ttgatgcagg caacggatta tgtagatgtt ttgattccac gtggtggtgc taaattaatt
     4201 cagaccgtta aggaaaaagc aaaagtgcct gtcatcgaaa caggtgtggg gaatgtgcat
     4261 atctatgtgg atgctcaagc tgacttagat atggctacta agattgttat caacgctaaa
     4321 acaaagcgcc caagtgtttg caatgcagct gagggattgg taattcacga agctgtagca
     4381 gcaaggttta ttcctatgct tgaaaaagcg atcaatcagg ttcagccagt agaatggcgg
     4441 gcagatgaca aggctttgcc gttatttgag caggcagtgc ctgcaaaagc agaggatttt
     4501 gagaccgaat ttttagatta tatcatgtct gttaaggttg tttcctcttt ggaagaagct
     4561 atttcttgga taaatcagca tactagtcac cattccgaag ctatcatcac aagggatatt
     4621 aaggcggcag agacctttca agatttagtg gatgctgctg ctgtttatgt caatgcttca
     4681 acacgattta ccgatggttt tgtttttggg cttggtgctg aaattgggat ttctactcaa
     4741 aaaatgcacg cccgtgggcc aatgggctta gaagccttga caagcactaa attttatatt
     4801 aatggggatg gacatatcag agaataagct actagaaggt cccttaatga ctaatgaaag
     4861 agaaaaagaa gaagcaaagg ttgctttaga agaactttta catcagattc aggtgattca
     4921 tttggaattg aaaattgtcc gaaattgggg ctattttgtt tttttggaga tggtatgctg
     4981 gtcagctgga tcaaacgtcg tgagcaagtt taaccaatta ttaatagact tacaagttac
     5041 tcttcaaaac tgccgaagat agctggcaga cgtcgatagg ctattattag ctgacttacc
     5101 gaatatgagt tgggataaaa tctttgatat ttggttagac aacctgctga cagattgttg
     5161 tgtgattaag gaagctaaaa atcttttaca agcagttgaa actctagagg cagcggctaa
     5221 gtcagtgctt gctaagttgg ctgatagcga acaaaaagaa caagattaga gaagaggaag
     5281 attcccacga gaatgaaatc cttttctctt actttttcat ttctaaacct tttgaagtat
     5341 ggtacaatta aagttatgac aaaagaattt catcacgtga ccgtactcct tcacgaaaca
     5401 gtggacatgc ttgacataaa gcctgatggg atttatgttg atgcgacgct aggtggctca
     5461 gggcactcag cttatttgtt gtccaaactt ggtgaagaag ggcacctcta ttgttttgac
     5521 caagaccaaa aggctattga caatgcacaa gttaccctcc aatcttatat tgacaaagga
     5581 caggtaactt ttattaaaga taattttaga cacctcaaag cacgtttaac agcgcttgga
     5641 gttgatgaaa ttgatggtat cttatacgac cttggtgttt ccagcccgca attggatgaa
     5701 agagaacgag ggttttctta taaacaagat gctccattgg atatgcgcat ggatcgtcag
     5761 tcgctcttaa cagcttacga agtggtgaat acctatccat tcaatgattt ggttaagatt
     5821 tttttcaaat atggtgaaga taaattctcc aagcagatcg ctcgaaaaat tgaacaagca
     5881 agagctatta agcctattga gacaacaaca gagttggcag aattgattaa ggcagcaaag
     5941 ccagctaaag agttgaagaa aaaaggccat cctgctaaac agatttttca agctattcgc
     6001 attgaagtca atgatgaatt gggagcggct gatgaatcta ttcaggacgc tatggaatta
     6061 ttagcccttg atggtcgtat ctcagtcatt accttccatt ctctggaaga tcgcctaacc
     6121 aagcagttgt ttaaagaagc tagtacggtg gatgtgccaa aagggcttcc tctaattcct
     6181 gaagatatga aaccgacatt tgaacttgtt tcacgtaagc cgatcttacc tagtcattca
     6241 gagttaacag ctaataaaag ggcacactca gccaagctac gtgttgccaa aaaaattcgg
     6301 aaataagcct atgacaaatg aaaaaagaac tcaggcagtt acaaatgcct tgcaaaaacg
     6361 aataaaaact ttctctagaa ttgagaaggc tttttatact gctatcattg taacagcgat
     6421 tacgatggca gtaagtatta tttacctgca aagtcgtaag ttgcagctac agcaagaaat
     6481 cactagttta aatagtcata tttcggatca aaaactagag cttaataatg ccaagcaaga
     6541 agtaaatgag ttatctcgcc gtgatcgtat tatagatatt gctggtaaag caggcttaag
     6601 caaccgtaat aataatatca agaaagtcga gtaatctatg aaaaaatggc aaaaatatgt
     6661 tttagattat gttgtgcgcg ataggagaac tccagtcgaa aatcgcgttc gagttggaca
     6721 aaatatgatg ctcttaacta tctttatttt ctttattttc attattaatt tcatgattat
     6781 tattggaaca gatcaaaagt ttggagttag tttgtcagaa ggggcgaaga aggtttatca
     6841 agaaaccgtt acgatccaag ctaagcgtgg gaccatttat gatcgaaatg gtacagctat
     6901 tgcagtggat tctacgactt atagcatata cgcaattttg gataaatcat ttgtctcggc
     6961 ttcagatgaa aagttatatg tacaaccttc tcagtatgaa acagtagctg atattttaaa
     7021 aaagcatctg ggaatgaaaa aaacagatgt aattaaacag cttaagcgta aaggactttt
     7081 ccaagtctcg tttggaccgt cagggtctgg catttcatat agtactatgt ctactattca
     7141 aaaggctatg gaagatgcca aaatcaaggg aattgctttc acaactagtc ctggtcgtat
     7201 gtatccaaat gggacatttg cttcagaatt tataggctta gcatctctaa cagaagataa
     7261 aaagacaggt gttaagagtt tagttggaaa aacaggtcta gaagcttctt ttgataaaat
     7321 tttatcaggt caagatggtg ttattactta tcaaaaagat cgaaatggga ccacactctt
     7381 gggtacaggt aagactgtca agaaagctat tgatggcaaa gatatttaca caacgctatc
     7441 tgagcctatc cagaccttct tagaaaccca gatggatgtt tttcaagcca aatcaaatgg
     7501 tcagttggcc agtgcaacac ttgttaatgc taaaactggt gaaattttgg caacaacaca
     7561 acgccccact tataatgctg atactctgaa aggacttgaa aatacgaact acaaatggta
     7621 cagtgcactt catcaaggaa attttgagcc aggctcaacc atgaaagtga tgactctggc
     7681 agcggctatt gatgataaag ttttcaaccc aaacgaaacc tttagcaatg ctaatggttt
     7741 aacaattgca gatgctacta ttcaagactg gtctattaac gaaggcattt ccacaggaca
     7801 gtacatgaat tatgcacaag ggtttgcctt ctcaagtaac gttgggatga ctaaacttga
     7861 acaaaaaatg ggtaatgcaa aatggatgaa ttatttgacg aagttccgct ttggttttcc
     7921 tactcgtttt ggtttaaaag atgaagacgc aggtatattt ccttctgata atatcgtgac
     7981 tcaagctatg agcgcttttg gtcaagggat ttctgtaacc cagattcaaa tgcttagagc
     8041 ttttactgct atttctaata atggtgagat gttagagcca caatttatca gtcaaattta
     8101 tgatcctaac acagcaagtt ttagaacggc aaataaagaa attgttggaa aacctgtatc
     8161 aaaaaaagcc gctagtgaaa caagacaata catgattggt gtaggaacag accctgagtt
     8221 tggaacactc tattcaaaaa catttggacc aattattaaa gtgggtgatt tacctgttgc
     8281 tgttaaatca ggaacagcac aaattggttc agaagatgga actggttatc aagatggtgg
     8341 attgactaac tatgtttatt cggttgtggc aatggtgcca gctgataaac cagacttttt
     8401 gatgtatgtt actatgacta aaccacaaca ttttggtccc cttttttggc aagatgtggt
     8461 taacccagta ttggaagaag catacttaat gcaagataca ctaactaagc cagtagtatc
     8521 agatgctaat cgtcaaacaa cttataaatt accaaacttt gtaggaaaga atcctggtga
     8581 gacatcaagc gagttgcgtc gaaatcttgt ccagccagtt gtccttggta ctggcagcaa
     8641 gatcaaaaaa gtatcgcatc agcccggtca aacgttaaca gaaaaccaac aagttctcat
     8701 attatcagac cgttttgtgg aggtaccaga catgtatggc tggacaaaat ccaatgttaa
     8761 aacctttgct aaatggactg ggatagacat cagctttaaa ggaacagatt ctggtcgtgt
     8821 tatgaaacaa agtgttgatg ttggtaagtc cttgaaaaaa ataaaaaaaa tgaccattac
     8881 tttaggagat taacatgttt ttaaccctta ttgcagcaat catatccttt atggtatctg
     8941 ctttcacaat gccttatttt atcaaattct atcaattgaa aaaaattggt gggcaacaaa
     9001 tgcatgaaga tgtcaagcaa catttagcta aagctggaac accgactatg gggggaactg
     9061 tttttctttt agtagctacg gcagtatcgt tattggttag tctattttcg atcaaaaaca
     9121 ctcaaagttt agctttgatt tcaggcattt tatcaattgt tgtcatttac gggattatcg
     9181 gatttttgga tgatttttta aaaattttta agcaaatcaa tgaaggattg acagccaaac
     9241 aaaaattagc cttgcagttg gctggaggat tgatgttcta ttttttacat gttagtccaa
     9301 gtggcatttc ttcgatcaat gtgtttggtt atcagctgtc gctgggaatt ttctacctat
     9361 tctttgttct attctgggtg gttggtttct caaatgccgt taatttgacg gatggtatcg
     9421 atggcttagc ttctatctca gtggtgatta gtttagtgac ttacggcgtt attgcctacg
     9481 ttcagagtca atttgatgtt ttgttactga ttggaaccat gattggtgct ttacttggtt
     9541 tcttcctatt taaccacaag cctgccaaag tatttatggg agatgtaggt agtttagccc
     9601 ttggagctat gttggcagct atttctattg cgcttcgtca agaatggacc ttactcatta
     9661 tcggaattgt ctacgttctt gaaacaagtt ctgtgatgtt gcaagtgtcc tatttcaagt
     9721 acaccaagaa aaaatatgga gaaggtcgtc gtatttttag aatgacgcct ttccaccacc
     9781 atttggaatt gggaggcttg tctggtaaag gcaagaagtg gtcagaatgg caggtagatg
     9841 cttttttgtg gggagtagga agtctagcta gtttactagt tttagctatc ttatacgtct
     9901 tctaaggggg attatcaaga atagtcacca atagcatttt gattaacatc atcaataaga
     9961 gagtggagat gacccacaaa tactgatttt gtgagtgttg tcccactcct tttgcttgtc
    10021 tctaacaata atgatataat atggaagaaa acgaggtaaa acatgtcatt taaagattat
    10081 cattttaaac aatacatcca gcaagcactg gaagaaattg gttttgtcaa tccaacagag
    10141 gtccagaagc ggctgattcc tattgttaac tccggtcgtg acttagttgg cgaatcaaaa
    10201 acaggttcag ggaaaaccca cacctttttg ttgcccattt ttgaaaaact tgatgaaact
    10261 aaagcagaag tgcaagtcgt tattacagca ccaagccgtg aattagcaac tcaaattttt
    10321 gatgcttgta aacagattgc taagcacttc caagaagaga ttcgtttggc caactatgtt
    10381 ggaggcacag acaaactccg tcagattgaa aaactaaaag gcagccagcc gcatattgtc
    10441 atcggaaccc caggtcgtat ttatgacttg gtcaagtctg gtgatttagc gattcataaa
    10501 gcaacgacct ttgttgtgga tgaggccgat atgaccatgg acatgggctt tttggatacg
    10561 gtagataaga ttgcagcttc gcttccaaaa tctgttcaga ttttggtgtt ctcagcaact
    10621 attccacaga aattacaacc ctttttgaaa aaatacttga ccaatcctgt tattgaacaa
    10681 atcaagacaa agaccgttat cgcagatacc attgataact ggcttgtgtc gacaaaaggg
    10741 cgtgataaga atggtcaact gttagagatt ctcaaaacca tgcagcctta tatggctatg
    10801 ctttttgtca ataccaagga acgcgcagat gatttgcatg cctttttaac agctaatggc
    10861 ttaaaagtgg ctaagattca tgggggcatt cctccaagag aacgtaagcg catcatgaac
    10921 caagtcaaaa aactggactt tgaatacatt gttgccacag acttagcagc gcgtgggatt
    10981 gacattgaag gggtcagcca tgtgatcaat gacgccatcc cacaagactt gtctttcttt
    11041 gtccatcgtg taggccgaac aggtcgaaat ggtatggcag gaactgccat tacactttac
    11101 cagccaagtg acgactcaga tatcaaagag ctggaaaaaa tggggattgc ctttacaccg
    11161 aaggtgctca aaaatggaga atttcaagat acctatgacc gtgatcgccg tcaaaaccgt
    11221 gaaaaagcct atcaaaaatt agacacagaa atgattggtt tggtgaagaa gaaaaagaaa
    11281 aaagtcaaac caggttacaa gaaaaaaatt cagtgggcgg ttgatgaaaa acgtcgcaaa
    11341 gaacgtcgtg ctgaaaatcg tgctaagggc cgcgctgagc gtaaggccaa aaaacaacat
    11401 ttttaagaac aaagagcaag caagtgatca attggcatct aatcttgctt tttttacacc
    11461 tgctacttgt attgtttacc atttgttaac acaaaaagtg atcatagctt ttgcttattg
    11521 ctataatacg gatttactat tttacatgtg ggtctaagag tgttagaata ttaagacaaa
    11581 caaatacaaa ggggaaatac atgacatcag tgtttttaac cagtggttgg gctttttatg
    11641 atcacctcat ctcaccgatt ccacatggga aactttttag ttggcatgct gtttttgatg
    11701 ccattccaaa tattatccaa cggcttccaa ttacgcttgg tttgacacta tcaggagcaa
    11761 cctttggctt ggttttggct ttgatttttg cccttgtcaa aattaataaa gtgaagctac
    11821 tataccctat tcaagctatt tttgtgagtt tcttgcgagg aactcctatt ttggtacagt
    11881 tgatgttgac ctactacggt attcccctct ttctaaaatg tctcaatcag aagtatggct
    11941 ttgattggaa tgttaatgca attccggctt ctatttttgc cattacagcc tttgctttta
    12001 atgaagcagc ctacgctagt gaaactattc gggcagccat tttatcagta gatacaggtg
    12061 aaattgaagc agcaaaaagt ctaggcatga cttctgtgca ggtttaccgt cgtgtcatta
    12121 ttcctaatgc aactgttgtg gctattccaa ccttgattaa tgggttaatt ggcttaacta
    12181 aaggaacatc gcttgccttt aatgcaggga ttgtcgaaat gtttgctcag gctcaaattc
    12241 taggcggatc agattaccgt tattttgaac gttatatctc tgttgctctt gtctattggt
    12301 ctatcagtat tttgatggag caagtaggtc gcttgattga aaacaagatg gccatcaaag
    12361 caccagaaca agctagaaat gaaaagttag gagaattgcg ttgatgatta caattagaaa
    12421 tttgagcaag acattctcag ggcaaaaagt tttagatagt ttggctcttg atattgaaaa
    12481 aggtcaagtg attgctttag ttggtgcttc aggagcaggg aaatcgacct tccttcgtag
    12541 cctaaactat ttggaaaaac cagattccgg ctccattagc attggtgact ttacggttga
    12601 ttttgagacc attaccacag agcaagtcct tattttacgt cggaaacttg ccatggtttt
    12661 tcaacaattt aatctttttg agcgtcgtac agcccttgag aatgtcaaag aaggtcttaa
    12721 ggtggtcaaa aaactgtctg accaagaagc gactaaactg gcgcaagcag aattggctaa
    12781 ggttggttta gcagatcgaa aacatcatta cccacgtcat ttatcagggg gacaaaaaca
    12841 acgggtagct ttagcaagag ctctggctat gaaaccagat gttttattac tagatgagcc
    12901 gacctcggct cttgacccgg aattagttgg cgaagtggaa aagtctatta ctgatgctgc
    12961 taaatccgga cagaccatgg ttttagtgag tcacgacatg aattttgttt accaagtggc
    13021 agatagagta ctctttttag atcaagggaa aatcttggaa caaggaacac ctgaagaagt
    13081 ctttagacat cctcaaaaag aacgaaccaa agaatttttt gcaagctatt caaaaacata
    13141 catttaatgt tattcttttg ttataataaa aaggtctagg tattcctggg cttttcttgt
    13201 tatgtttttt agaaaaactt atgggaaaga aataatgact aggtggaagt atgttagtag
    13261 aaatctttag cctttatgta aaaggtctca ttctctcaag ccttactatg attttaattt
    13321 gtttaatatg gactttatgg cgagcaaaaa ccaaaagaga taaaacattg attgaaagac
    13381 aagcttttct ttatgagatg ctaatggttg ctattttaac catcccaatt ttatcgtttg
    13441 cttttatgag tattttggtt gtcataaaat cctaatcatt gcaagaaggg attatcattg
    13501 ctaaaatatt ggcaagagta gattaaagga gaaaaatcat gtacgataca ttaattattg
    13561 gttcaggacc agcaggaatg actgccgctt tatacgctgc tagaagtaat ttatctgttg
    13621 ccattattga acaaggggca cctggtggtc agatgaacaa cacttttgat atagagaatt
    13681 acccgggata tgatcatata tctggaccag aattagctat gaaaatgtac gaacctttag
    13741 agaagtttaa cgttgaaaac atttatggta ttgttcaaaa aatagaaaat tttggtgact
    13801 ataagtgtgt gttgactgaa gatgctagtt atgaagctaa aacggttatt attgcaacgg
    13861 gagctaaata ccgtgtacta ggtgttccag gtgaagaata ctatactagt cgaggagttt
    13921 cttattgtgc agtatgtgat ggtgcgtttt tccgtgacca ggatcttttg gtcgttggtg
    13981 gtggtgactc agcagttgaa gaagctattt atcttactca gtttgctaaa aaggtaaccg
    14041 ttgttcatcg ccgtgatcaa ctaagagctc aaaaaatact gcaagatcgt gcttttgcca
    14101 atgataaggt cgactttatc tgggattcag tcgtcaaaga aattcaaggc aatgatatta
    14161 aggtctccaa tgtcctaatc gaaaatgtga aaacaggcca agtcactgac cacgcttttg
    14221 gaggtgtgtt tatctatgtt ggtatgaatc ctgtgacagg tatggtaaag gatctagaaa
    14281 ttaccgattc agaaggttgg attatcacag atgatcatat gaggacaagt attcctggta
    14341 tttttgcgat tggagatgtt cgtcaaaaag accttcgcca aatcacgaca gctgttggag
    14401 atggtgcaat tgcagggcaa ggtgtttatc actaccttga aagtttccct tcataaggtt
    14461 aaaactcctt catttctcct tgtctttccc ttaaaaaagc taaattgcat aagaccttta
    14521 agaaatataa agaacagttc tccttaatat ctttcctaga taaatgttga aaattttctg
    14581 aaaaaaggat ataataaata gtattttagt gaatggagtt tagaatgtct ataaaagaac
    14641 aaacagacaa taacgaacta gaaaatggaa tggtaagggg cttagaaaat cgtcatgtgc
    14701 agttaattgc gattgcagga acgattggaa caggtctctt tttaggggca ggacgctcta
    14761 ttgccttaac aggaccatct attatttttg tgtatatgat tacaggtgcc ttcatgttta
    14821 tgatgatgcg tgccatcggt gaaatgctct attatgatcc agatcaacac acctttatca
    14881 attttatttc caaatacatt ggtccaggct ggggttattt ttcgggtcta tcctattgga
    14941 tttcccttat ttttattgga atggcagaaa tcacagcagt aggtgcttat gtgcaatttt
    15001 ggttcccaag ctggccagcc tggttgattc agttggtttt cttagtctta cttagttcga
    15061 tcaacttaat tgctgtgcgc gtttttgggg aaacagagtt ttggtttgcc atgattaaga
    15121 ttttagctat tttagctttg attgcaacag ctattttcat ggtattgaca ggttttgaaa
    15181 ctcacacagg ccatgctagc ctttccaata tttttgacca tttttccatg ttcccaaatg
    15241 ggaaactaaa gttctttatg gccttccaaa tggttttctt tgcttatcaa gctatcgaat
    15301 ttgtggggat taccacttct gagacggcta acccaagaaa agttttacca aaggctattc
    15361 aagaaattcc aacccgtatt gtgatctttt atgtgggagc cttggtctct attatggcaa
    15421 ttgtgccatg gcatcagtta ccagttgatg aatctccttt tgtgatggtg ttcaaattga
    15481 ttggtattaa atgggcagca gccttgatta actttgtggt cttgacatca gcagcgtcag
    15541 cgcttaactc aaccctttat tcaaccggtc gtcatctcta tcagattgct aatgagactc
    15601 caaacgcttt gaccaatcgc ttaaagatta atactttatc tcgacaaggg gtgccaagtc
    15661 gtgccattat tgcttcagcg gttgtggttg gtatctcagc tttgattaat atcctaccag
    15721 gagttgcaga tgcgttctca ctcattacgg cctcctcatc aggtgtatac attgctatct
    15781 acgccttaac catgattgct cactggaagt accgtcaatc taaggacttt atggcagatg
    15841 gttatttgat gccaaaatat aaagtgacaa cgcctttgac ccttgctttc tttgcttttg
    15901 tctttatctc tcttttctta caagaatcca cctatatcgg cgccattgga gcaacgattt
    15961 ggattattgt ttttgggatt tatagcaatg tcaaatttaa ataataatta gcgatataga
    16021 actgaatcca ttaactcttt cttatttgag gatgtcatga tggatcagtt ctttttttac
    16081 tttagcgata acttaagtta tttctaaatc ctagccaaag agtccttttt aaaatatgtt
    16141 ataatagtaa caataattca aaggagtccc ctttatgtat aaagatgata gtttaactct
    16201 ccatactgat ttgtatcaga ttaatatgat gcaagtttat tttgagcagg gcattcataa
    16261 tcgtcatgcg gtgtttgaag tctatttccg caaggaacct tttaacaatg gttatgctgt
    16321 ttttgccggt ttacagcgca tggtggagta cctagagcag tttcaatttt cagaaacaga
    16381 tttggcttac cttgaagaac tgggttatcc agaaaacttt ttgacctacc ttaaagagtt
    16441 acgattagaa ttgaccatcc gttcagctaa agaaggagat ttggtttttg ctaatgagcc
    16501 gattgtgcaa gtagaaggcc ctctaggtca gtgtcagttg gtcgaaacag ctcttttaaa
    16561 cattgttaac ttccagacct tgattgctac aaaggctgct cgtattcgtt ctgtgattga
    16621 ggatgaaccc cttttggaat ttggcacccg tcgtgcacag gaactagatg ctgcgatttg
    16681 gggaacccgc gcagcgatta ttggtggagc agatgcaaca agtaatgtga gagcaggtaa
    16741 acgctttggt atccctgttt caggtacgca tgctcatgct ttagtgcaag cctatggtaa
    16801 tgattatgat gctttcatgg cttatgctaa gacccacaaa gattgtgtgt ttcttgttga
    16861 tacctatgac acgcttaaag taggtgtgcc aacagctatc cgagtagcca aagaaatggg
    16921 tgacaagatt aattttctag gtgttcgatt ggactctggt gacttggctt acctctcaaa
    16981 aacagtccgt cagcagttag acgacgctgg ttttaccgag gctaagatct atgcttctaa
    17041 tgacctcgat gaaaatacca tcctcaactt aaaaatgcaa aaggccaaaa ttgatgtttg
    17101 gggtgttggg accaaactga tcacagccta tgatcagcct gccttaggtg ctgtttataa
    17161 gattgtctct attgagcaag aagatggtag catgcgtgat acgatcaaat tatcaaataa
    17221 tgcagaaaaa gtatccacac caggtaaaaa acaagtttgg cgcatcacca gtcgtgaaaa
    17281 aggcaaatca gaaggcgact atatcacgtt tactgatatt aatgttaatg aattaactga
    17341 gattgagatg ttccatccga cctataccta tattaagaaa accgtcagaa attttgatgc
    17401 aattcctctc ttagttgata tttttgtcaa gggagaatta gtttaccagc taccgacctt
    17461 atctgaaatc aaggcttatg ctaaaaaaga atttgacaag ctttgggatg aatacaagcg
    17521 tgtcttaaat cctcaagact acccagtaga cttggcacga gatgtttggc aaaataagat
    17581 ggccttaatt gataacattc gtaaagatac tcatggaaag agtgatttaa aatgacctta
    17641 caagaagaga ttatccgaca attaggcgtc aaggctagca ttgacccaca agaagaaatt
    17701 cggaaaacag ttgatttttt aaaagcttat ctgcgtaagc actcattttt gaaaacttat
    17761 gtcttaggca tttctggagg tcaggattct accctcgcag gaaagctagc ccagatggcc
    17821 attgcagagt tacgggagga aacaagtgat caagcttacc aatttatagc tgttcgcttg
    17881 ccttacgggg ttcaggctga tgaagcagat gcacaaaagg ccttggcttt tattgcacca
    17941 gatcagaccc ttaccattaa tatcaaggca gctgtggacg gtcaagcagt agccttgcaa
    18001 caagctggca tcgagatttc tgatttcaat aaaggtaata ttaaagcacg tcagcgaatg
    18061 ataagtcaat atgccattgc tggccaaatg gctggtgctg ttattggaac ggatcatgcg
    18121 gcagaaaaca tcactggttt ctttactaaa tttggtgatg gtggagcaga tattcttccc
    18181 ctctttaggc ttaacaaacg tcaaggaaag gctcttttga aagttttagg agcagatgct
    18241 gctttgtatg aaaaagttcc aactgctgat ttagaagatc aaaaaccagg cttggctgat
    18301 gaggttgctc tagaggtgac ctatcaagac atcgacgact atttggaagg gaagctgatt
    18361 tccaaagtag ctcaagcaac tattgaaaaa tggtggcata aaggacaaca caagcgtcac
    18421 ctgccaatca ccatttttga tgatttttgg aaataagaga tgatgttcaa agagtaaaaa
    18481 aagaaaacaa aaaaagttag gttatcctaa cttttttctt gaagaaaatc aaataaggtc
    18541 tataatagaa gtaatccttt agaatagaat ggctggataa taaccatctt gccaatatta
    18601 tttcaggtga agcttatctt aatattttag gaggacaata atgtcagcat taacagagac
    18661 atttacagaa caactatttg ctcattacga agccagtgca aaattttcag ctattgagaa
    18721 tgccgttacg cataatggtt tgctaaaatc attagaaacc cgtcaaagtg aagtggacaa
    18781 tgattttgtg ttttctattg atttaactaa agataaggta tctaaccaaa aggcttctgg
    18841 tcgttgctgg atgtttgctg ccttgaacac tttccgacac aaattaatca cagagtttaa
    18901 attagaaaat tttgaactgt cacaagctca tactttcttt tgggataagt atgaaaaagc
    18961 taactggttt atggagcagg tcattgctac agctgaccaa gaattaacca gtcgtaaagt
    19021 taagtttctc ttggatgttc cacaacaaga tggtggtcag tgggacatgg tagtttcctt
    19081 gtttgagaag tatggagtgg tgccaaaatc tgtttaccca gaatcaatct catcaagtaa
    19141 cagtcgtgaa ttaaaccagt atttgaataa attattgcgc caagatgctc aaattcttcg
    19201 tgacctgatt gcgtcaggcg ctaaggcaga ccaagttgag gatcgaaaag cagagcttct
    19261 tcaggaaatt tttaacttct tggccatgac ccttggttta ccacctcgtc attttgattt
    19321 tgcctaccgt gataaagatg accactatca tgttgagaaa ggtttgacac cgcaagcgtt
    19381 ttacgacaaa tttgttggct taaagctttc tgattatgtg tctgttatta atgcgccaac
    19441 tgctgataag ccttatggca aatcatacac tgttgagatg ctaggaaatg tggtcggtag
    19501 tcgtgaggtt cgctacctca accttgatat gaaacgtttc aaagaactag ctatcaagca
    19561 gatgcaggct ggtgagtccg tttggtttgg ctctgatgtg ggtcaagttt cagatcgtca
    19621 aaaaggcatt ttggcaacta atacttacga ttttgaagct agtatggata tcaatcttag
    19681 tcaagataag gctggacgtt tggattatag tgaaagtttg atgacacatg ctatggtttt
    19741 aacaggtgtt gacttagatg aaacaggaaa accattaaaa tggaaggttg aaaattcatg
    19801 gggtgagaag gttggtgaca aaggttactt tgttgcttca gatgcttgga tggatgaata
    19861 tacctatcaa attgttgtcc gtaaagaatt cttaacagct gacgagttag cggcttatga
    19921 aaaagagcca caagtactag ctccctggga tccaatgggt gctttagcac aatactaatt
    19981 cctttctttg cgactgtatg aaatctaaaa gctggacaaa acgaacagca aacggattgg
    20041 actccgcata agaaagtgaa catgaaaaaa attatgatgc taagaaaatg acatatgaaa
    20101 aaacacgtct tcggtatatg gaaacgtgtt tttttcatgt atactctctt atggcattag
    20161 ttgctattta taacaatttt aaataagtct attttatttt aggttaacgt ttgaaaaatc
    20221 agttgctaat tcccttaacg ttgtaccttt tctttaatac gattaaagaa ttctgttttt
    20281 tgttttatat tgtatgtggt aggtcatttg tgtcatataa aaacgagtcc tcacagaacg
    20341 tggactcgct ttttatttag attatcactt aaggtagata ttaaaagtaa gtaaatggat
    20401 atgtaataaa aggtaggtac agacaataag tagagttaga gattaatgag ttgtcttttt
    20461 atcatcggta gatggatgat tgctattgtt gtctgtattg gttgaattac ttgtatcatt
    20521 gctactacta gtatcatctg aagtcgtttg gctagaagct gttgtcgtgt tattgctgta
    20581 aagattgttg taaaccgaat tagtatagtc ggtgttgctc gcataggttc cgcttaagta
    20641 gaggaatcca ccactgcgat aaagaccatt tggcatcgtc caatcttcac tgtaaccatt
    20701 tgttaagtaa gtcatcatgc tacgataaac gtcagatgca atctctagac ttgatccgta
    20761 gactggggtc aagcggtttt tgtaacctgt ccaaacagcc atggcgtagc gcttagtaaa
    20821 gccaacaaag ttttcgtctg gcgctaatgt accaacataa tctggataaa ggccgtattt
    20881 ttcaccaatt ttagctagtt cctcatcagt gtagttagaa gtccctgttt taccagcttg
    20941 cgcaacacca ggaatggcag cagcggtgcc tgtaccataa gtgagaacag tttttaacat
    21001 atctgtcatc atataggccg tggtttcttt catggcacgt tttccttttt catcaaaagt
    21061 tttacttgta ccatcactaa attccacttt attgacatac cttggtttat gataaatacc
    21121 accatttgca aaagcagcgt atgcagcggc cattttttca ctacttgcac catatttttt
    21181 atctgagcta ctgttattac ttgagatagc gtttgagtag tgcatttcgg gatagttaat
    21241 acctaaactg cttaagaaag atcgagcata gtcaagtcct gcggcttcca gtgctcggac
    21301 tgctgggaca tttcgcgata gcataatagc agcttggatt gtcatccatc cgttatatct
    21361 aaggtcccag ttaaacaatt gggtagtggt tccaggccaa taatagactg agtcattagt
    21421 cgactgagca gtagaagtat aaacaccaga ttcaatagca ggagcatagg ctgtgattgg
    21481 cttcatggta gaaccccagt cacgatcagt taaaacagct tggttagtcc caaatgaaac
    21541 attttcatct tgattacgtc cgccaagctg agcaataaca tgaccatttg tcacatcaac
    21601 aatcgttgaa gcaacttgga aatcttggtc tggatagtaa acataatcac cagaatgata
    21661 aatattataa agagtctgct gcgcatcggg gataatatta gtataaactt ttaaaccagc
    21721 ggtaaaaata tctttatttg tttctttttt gacttcttca ataacttgtt ttagataatt
    21781 atccatatat tttggataag ttgagcgctg ttggagtgat tgtagacctt cagcgacggg
    21841 agttgcgatg gcagtttcat attctgcttt cgtcagatgt ttttccatgt acatctgttg
    21901 caacacgacg ttacggcgat tttgagcagc ttcaggatga aggtaaggat catattgact
    21961 aggagcttga gggattccag ccaatagggc tagctgggca taagataaat ccttaagatc
    22021 cttgccataa taagacttag cggctgtcag cataccatag ttgccattac ccatatatac
    22081 tttgttgatg taaaaagtca ggatttcttg tttagtatat tttcgctcca tttgaagagc
    22141 aagccaaact tcttgagcct tacgttttaa ggtttgatca gattcattag tagaaaaata
    22201 ggctagttta atgagttgct gatcaagcgt tgacccccct tgagtggtct gactcgttag
    22261 attatgaaag gcagcaccaa aaatacgata aagatctact ccacgatggt taaagaaacg
    22321 tttatcttca attgaggtaa tagcattaac tagattaata gggatactat cagctgttac
    22381 attttcacgc ttttcagaac ccaaatcagc aatcagattg ttattaccgt cataaaccaa
    22441 gctagagttt gttgatttta actgggcttc tgacagtttc ggagcactgc taatgtagaa
    22501 ggtaaacaaa agaccaccaa taataataac aaggataata aggctaagaa ttgcacttaa
    22561 tacatacttt agccacttaa ggatttttgg atttttaatt gtaatcaccg cctaaaaaat
    22621 tttgttcaat tatgtttaaa taagggactt gtggaaaggc tccaaatgct accttaaagc
    22681 cattttttct gatataatca atgggcatcg atttactgcc attatctatc tgataaaatg
    22741 aaatcaaggc ttgagcaggt aggtagtaag tctccttcag tgtggaaaag tgaagaagga
    22801 caaagcagat tcctttttga tgtaaaacgc aagccatatg ttcaatctga tgtaaatgga
    22861 aatttttcat gggcatagct gttttttgcc tggtttcttt tgcttcaaaa tcaacataat
    22921 gtcctttata aacgccgcaa tagtcagtcg ttgaagcttg tctaaagtat gcttcaacga
    22981 tttttgcccg actgcgctta gggtaatcaa ctttgacaat ttggacagga gtaggttttt
    23041 tgtgaatgac agctatttga cgagataaat aataatcatt tgtcgcgttg atagcagctt
    23101 caaaggacat acctctattg gcgaagtcca ccttattttg ctttgtttgc ttttgaacgg
    23161 aacttacttt ttgtcgaata agattatgag gataattaac cattgttctc ctaatattat
    23221 ctagttaatg ctaaaaattt aagcactttt attataacat attttttgaa aggataacac
    23281 ctaatgactg cgattctaat tacaggttac cgaagctttg aaatagggat ttttgaccat
    23341 aaagacccac gagtttcaat tattaaacag gctattcgta aagatttaat aggttatttg
    23401 gaaaacggtg tggattggtt tatctttaca gggaacttgg gttttgaaca atgggctttg
    23461 gaagtagcta atgagctaaa agaggagtat cccttgcaga tagctactat attcttgttt
    23521 gaaacgcatg gagataggtg gaatgaaaaa aatcaagaag ttttaagtca gtttagggct
    23581 gttgactttg taaaatatta ctttccaaat tacgaacaac cgacgcaatt tagtcaatat
    23641 tatcagtttt tattagaaaa gacagaaggg gcttatgttt tttatgacac agaaaacgag
    23701 accaacttaa aatattttct caagaaagca aaagatatgc cgcattatca gttgctattg
    23761 ctaacctttg atcggctaaa tgatatgtca caaagctagc attgtatttt taggggtatt
    23821 ggtatttaaa tacttgcttt ttgaactatt tttctgtatc attaataata atactgaaat
    23881 ataattttgg taaaaagatt gaccgttcgg agagtaaaga atgacaagta ttatttatag
    23941 tcctaaagat atttttgagc aagaatttaa gactagtatg cgagggtttg ataagaaaga
    24001 agttgatgaa tttcttgata atgtaattaa agattatgaa aatttcaatg ctcaaattga
    24061 agctttaaaa gctgagaacg aagccttaaa aaaggcgaag tttcaagcta gaaatacagt
    24121 ttcagcgact gttcaacaac cagtaccgca accgactcgt attgctcaat cagctactaa
    24181 ttttgacatc ttgaaacgta ttagtaaatt ggaaaaagag gtttttggta aacaaattat
    24241 tgagtaatga aaactgtgca atttttggat aatcgcgtag tattttaata ctatgaggaa
    24301 agtccatgct agcactggct gtgatgccag tagtgattgt gctaggcgaa cacataagcc
    24361 tagggatgtg catacacatt acggcgaagg aaatggctaa gtcgtttgat atgccaaagt
    24421 acttctgaaa gtgccacagt gacgtagttt ttatggaaac gtaaaaaatg gaacgcggta
    24481 aacccctcaa gctagcaacc caaactttgg taggggcatg ggatagttgg aaacgaacaa
    24541 gctatcctga ctgtcaacag acggtagaca gatgattatc gaaggaaata attcctagtt
    24601 atttccggaa caaaacatgg cttatagaaa attgcataat aggttaagct agcacttgct
    24661 agcttttatt tgatttaaaa gaaagagata tatgaaagaa acatttagat tagtcgcaac
    24721 tgcagccgca ggtttagaag ctgtcgttgg taaagaagtc agagcactag gctttgattg
    24781 tcaggttgaa aatgggaaag tttattttga aggtgatgta gaagcgattg ttaaaacaaa
    24841 tctttggtta cgtgcagcag atcgtatcaa aattatcgta ggacaatttc ctgctagaac
    24901 ctttgaagaa ttattccaag gtgtctttgc cttggattgg gaaaattatt taccgctagg
    24961 agctaaattt ccaatctcaa aagccaaatg tgttaagtct aaattgcata acgagccaag
    25021 tgttcaggcg attaccaaaa aggccgttgt taagaaactg caaaagcatt tccacaggcc
    25081 agaaggagtt cctcttcaag aagttgggtc aacgtttaac attgaggtat ctattttaaa
    25141 agaccaagcc actattatga ttgacacgac aggatctagc ctatttaaac gagggtatcg
    25201 cgttcaaaaa ggtggagcac cgatcaagga aaatatggca gctgctatct tggccttatc
    25261 taactggttt ccagataaac ctctggttga tcccacctgt ggatcgggaa cgttttgcat
    25321 cgaggcagcc ctgattggga tgaatattgc tccaggattt aaccgttcgt ttgcttttga
    25381 agaatggagc tgggtagata aagacatggt gcaacaagtt cgtgatgatg ctgaacaaga
    25441 agctaattat gaaatcgaat tagatatttc tggctttgat atcgatggcc gcatgattga
    25501 gattgctaaa agtaatgctg aagaagctgg tttatctgat gtgattacct ttaagcaaat
    25561 gcgtctgcaa gactttcgaa cagacaagat taatggtgta gtgatatcaa atcctcctta
    25621 tggagaacgg ttgcttgatg acaaagcggt tgacatcttg tataatgaaa tgggacaaac
    25681 ctttgcacca ttgaaaacat ggagcaaatt tatccttaca agtgatgaac tttttgaact
    25741 aaaatacggg caaaaagctg ataaaaaacg taaactttat aacggcaccc taaaagttga
    25801 tttgtaccaa ttttatgggg aaagggtaaa gcgacatctg atatagagag gtagtaagcg
    25861 tgtcagaaga aagcaaagaa gtcgaagtaa caaaagaatc gcaaacattg gggcttaatg
    25921 aagccaagtc aatgacaatt ggtgaagctg tacgcaaaca gtcagagata aaagcaggtg
    25981 ttactaagga tgatagtatt ttagataagt acattaagca acaccgtgac gaagtttctt
    26041 ctcaaaagtt tgatgctaag tatacagagc ttgatacagc tagtttagat aactttatca
    26101 aaaaacaaag agaagcattg agtaaagccg gtcttgttga tgacgaacct gtgtctgcgg
    26161 agtctgctga gcaagatagc actttggttg aagaagtagc tgaagactta gctccaatgg
    26221 agactactgc ggtggtaact gggattccgg tggaagcgac agtccctgtg ttagatctag
    26281 atccatcaga gagggtcatt ccggaaccac agataaccaa agaagagcca aaaagagatc
    26341 agtttctttc tgaagatagc caccatccag ccaaacaaaa cacgaaaaaa ggttggttaa
    26401 tagctttatt tctgctatta ttggccattc ttgcagttgt atttggttgg aaccatttct
    26461 tgagacaaga cagtggtaaa acaactcaaa cagcaagtaa acagacaaag acctctttgc
    26521 agaccgacag tgctaaaaaa gcaacgcgct tgaaggctgc tgctaaagct ttcgaaaaac
    26581 aatatggtac tttttataca gatgccacaa agagcaaatt aaaaaatagt gcctttgcta
    26641 ctttgccaga tttagaagct gccttgaaag ctttggaagg ctctgcttac tatgataagg
    26701 cgaaagcaaa agtcgattcc cttaagaaag ctattgctgc tattacagcg gttaacggta
    26761 aatttgtttc cgatgttgtt gtagatggtg aaaaggtttc ggctgaagtc aaggctgatg
    26821 ctaattttga tgatttatca agtgcaacct tgacaacagg aaatgcaaat cttgatgctg
    26881 tcttgcaggc aagcatcaca gaaggtcgtc agcagctagc cagcaaggct gaggccgcta
    26941 aagcagctaa tgagcaagca gcccaggctc aagcagctca aggacaaagt acatcagtag
    27001 caccatctgg ctatggcttg acaagttatg accctgcaag cttacaacgg catttatcac
    27061 gtgtacctta caatcaagat gttattgctg atagagctaa cccatcttgg gcatttaatc
    27121 caggagttct tgaaaaaatt gtagcaacct cacaagctag aggttatatt tcaggcaacc
    27181 aatatatttt agagccggtt aatattatta atggcaatgg ttactataat atgtttaagc
    27241 ctgatggcac ttatttgttc tctattaatt gtaagacggg ttattttgta ggaaatggca
    27301 aaggttatgc tgatgcttta gattactgag aaaatcaaaa aaactgagat aaggcaactt
    27361 gtctcagttt tttgattaat aaggtatgtt gtcttaaaat ctgcagatag acttgttttt
    27421 tgtaacaagt aaaataggtc aataggattg ttatgtttga caacacacta gtatcagatg
    27481 acatggcgac taaaaggatc gtctgaaatc ccttgatcaa taatcaattg agcccattct
    27541 ttggcggcaa agaggctatg atccttatag ttcccacagg attcaagagt tgttccagga
    27601 acatcttccc aagtagtccc agttgcaatt tcttctaggc tggatttaat caccttggca
    27661 atatcagtag aactgtgttt tccccacatg ataaggtgaa aacctgttcg acagccaaaa
    27721 ggagagcaat caatcatccc atcaatgcgt tggcggatga gcttggcaag taagtgttca
    27781 atggtatgca aaccggctgt ttcaatagaa ttttggttag gctgcactag gcgaacatca
    27841 aaatttgtaa tacgatcgcc cttgggtcca aattcttcag aaataagacg aacataaggg
    27901 gcctttacaa tagtatgatc tagctcaaaa ctttcgacga taacttcttt tgtcatttca
    27961 atctcctttg ttttacactt tatcataaca caaatagtga gaaagtggct acttgtggag
    28021 gagaaaaggc taagaaaaca gatcaaaggc tatcacaatg acctgtgcga taaaagtact
    28081 tacagaaaca gtaataaaag tttctttaaa agcatttttg tggttaagtc ctgtcaatgc
    28141 taagaaggtg agaaagacac cactttgggg cacaatggta aagatattcg aagcaatagt
    28201 ggcaacacgg tgaatcattt cgggattaag gccttgatct aaataatact gggcaaaatt
    28261 aggcatgaca attcctagag cacctgaaga agaaccggta atagctgaca tagaggaagt
    28321 caacacggct aaactaataa gaggattacc gggaatattc aaaatgagat ctgagaagaa
    28381 tgtgaaacct ggggcaatca tcacaacggc tccgaaggca actgcagatg ctgtcgcaaa
    28441 aataggtgca atagagctgc tagctcctaa attaaagaca gcaatcttat taggaataaa
    28501 ctgtctaaag agccagcttg cggtgagaat ggcagctaaa agtgctatga aaataatgtt
    28561 cttcttaaaa aaatcgtttc cgaaaaggct accggttagg gcgataataa tgagcaacaa
    28621 taaaggtaag atactggcaa ggaaatgtgg gagatttttt gttttcactt gtatctcatt
    28681 gtcaaaagca taagtggcat aagtttcacc cattgccata ctttttgcta gacaatattt
    28741 catataaaag agcccaaaag tcacgcagcc gattgagcca acgatactcg gaatggcggc
    28801 agcagttagt gaggtgtcca agtattgaat aggaataaca ttttgaatgg caggtgttcc
    28861 gggtaaaatc gtcatggtaa aagtcgcaat accgagccaa agaggaactt gaattaagtt
    28921 ccaagccaag tccatttttt tgaatagact tcgtgcaagc ggcaagacag caaacatgac
    28981 aacaaagagg ctgattcccc cgtaagttaa tatagcactg attagaaaaa tagcaacgag
    29041 tactttataa ggactatcat gaccaacttt ttttaaaata taatctgcaa tagaagtggt
    29101 tgcaccgctt gtttccatta atttggctaa gatagaacct aataaaaaga tagcaaaata
    29161 attgagaata taagtggaga gtgcccccat aaattggttg ggttcttttc caagtaaggt
    29221 tttggttgga tccatttgat taaacaaaat gaccaagctg gtagcaagag gcgcagcgat
    29281 gataatgtta acttctttga cagacaggta aataataaca ataacaccta ccaagacccc
    29341 cagagaacca ataatttcta tagttttatg acctccttat tagaaaataa agagacagat
    29401 cacaagatac agcctcttta tctctccaaa tttattgagc aatgtagcca ccgtctaaga
    29461 tacaggcttg acctgtaaca ccttttgcct tatcactggc aaggaaagac acatagtctg
    29521 caatttcttg aacgtcaatg aggcgttttt gaggaacaag tgggtatagc acttcttcaa
    29581 gaacattttc aaggggaata cctcttgttt tggaaaggtc ttcaaactgg ccacgaacca
    29641 gtggtgtgtc aacatatcca ggacaaatgg cattgaccgt aatgcctgaa tcagcagctt
    29701 ctaaggcagt tactttggtc agaccgatca agccgtgctt agctgaattg taggcggatt
    29761 tgccagcaaa accaatgaca ccattgatag aagccatatt aataatacga ccgtgttttt
    29821 gagctttcat tgtaggaaaa gcacgtttaa tggcaataaa tggtgctgtc aacatgattt
    29881 taatcatgaa ttcaaatttt tcagttggaa aatcttcaat catggcaaca tgttgaaggc
    29941 ctgcgttgtt aaccaaaata tcaatacgac catatttttc aacaaccgta tcaatagcag
    30001 cattgatggc ttcttctttg gtgacatcgc acacaacact aaaagcgtca tagccttctt
    30061 tagtatagtc agcaacaacc tgatccagtt tttcttgatt aatgtcggaa aaaacaaccg
    30121 ttttaccttc ttttaataag gtttccccga tttgttttcc aattccgctt gcagcaccag
    30181 tgataaatgc aacttcttta gtatgtgtca tgatactatc ctcgtctttc ttttggttag
    30241 tctttagttt gttttatcaa ttagggtaac ttcggtaacg ttttgcacgt cttcaaaggt
    30301 gtaatctggg ttaatttcaa gggcgcatag accttcatct tgatattcaa agactcccat
    30361 ttcagtaatg attaggttaa caacattttg agcagtcaga ggaagggtgc atttgtctaa
    30421 aatttttgct ttgcctttat tggtatgctc cattgcaaca atgacttttt tagcacctac
    30481 caataagtcc atggcccctc ccatcccagg aaccattttt ccaggaatca ggtaattagc
    30541 aatgctagct tctttatcaa cttgtaaggc acctaagacg gttgcggcca catggccgcc
    30601 tcgaataata ccaaaggaag ttgagctatc gaagaaagcc cctccaggag caatactaac
    30661 aggttgtcca ccagcattaa caatactagg atcgtagtga tcatctgtta atccagtgag
    30721 accgacaaaa ccattttcgg actgcagggt aatggttaca ccttcaggaa tatagttggc
    30781 tacttttgtt ggcaaaccta tgcctaagtt gaccagtgta ttgtgttcta attcttgtgc
    30841 aacgcgctta gcaatacgtg tttgaatctc ttcttttgaa agaacagtag ctgatgttcc
    30901 catgttaggc tcctttcact aagtagttaa caaaaatgcc aggagtatgg acaaaattag
    30961 gatccatttg ccccacgtca acaatttctc ttgcttcaac aatggtggtt ttcgcattag
    31021 cagccatcac atgattaaag ttattttcag aacctgcgta ttgcaaattg ccatttttat
    31081 ctgccttgtt agcaaaaata agtgcgatat cagctttcaa aggtttttca agaaggtagt
    31141 ctttgccgtc aatagtaatg acttcttttc ctttggcaac ttcggttcct attccagtag
    31201 gtgttaagaa accgcctagc ccaaaaccgc cactgcggat gcgctcagct aatgttccct
    31261 gaggtacaag atcaattaca gtctcgccct cagtcatttg tcggcccgct tcacggttga
    31321 gaccgatatg tgatgcaata tatagttgaa aactgtttat tggcaaccat cttaccaacg
    31381 cctttgtcag gaaaaacagc atcgttacag attaaagtga ggtctttgac acctttttcc
    31441 acaagtgcat caattaattt ttctggtgtg ccatttgtca tgaagccacc aaccataatg
    31501 gtatcaccat ctttaacgtg agctaccgct tcttttatta tgatttcttt acctattttt
    31561 tctaccaact ttcacgagac taagtattgt ttttcacgat aacagcagtt ccttgtcctc
    31621 caccaatgca aagtgttgct agtcctctgg ttacttggcg ttttttcatt tcgtggatta
    31681 atgtgactag aatgcgagcg ccactggcac caataggatg acctaaagcg atggctcctc
    31741 cattaacatt cacgatttct gggtttaact ttaaatcttt taaaaccgcc aaggactgtg
    31801 ctgcaaatgc ttcattggac tccactaagt ccaaatcaga aattgttaat ccagctttct
    31861 taagggcttt ttgagtggca ggaattggtc cagttcccat cagttcaggt gcaacacctg
    31921 cactagcata gctttcaata gtgactaaag gtgttaaccc taattcaaga gctttttctt
    31981 cagtcattaa catcaataag gctgcaccat cgtttattcc tgaggcattc ccagcagtaa
    32041 cggttccttc tttagggagg aaagcaggac gtaattgctg taatttttca aggcttgtgt
    32101 caacttttgg gtattcatcc gtagtaacaa ttaaaggatc tttgcgtcgt tgaggcacag
    32161 agacagggac aatttcgtca gcaaaacgat gatttcctaa tgccttagca gctttttctt
    32221 ggctttctaa agcaaattga tcttgctctt ctcttgagat gccatatttc tgagcaacgt
    32281 tttcagcagt aatacccatg tggtaattat taaaagcatc tgttaagcca tcatgaacaa
    32341 gagtatcaat caattgacta ttaccaagac gttgaccaaa gcggtgctga gttgagacat
    32401 aagctgcttg tgacatgttt tccacaccac cagcaataac gatatcagcg tcaccaagca
    32461 tgatgctttg cgcagctaat tggattgctt taagcccaga accgcaaacc atatctaatg
    32521 tgaaagctgt tttatcttca ggaattcctg agtggactgc aacttgtctt gccacatttt
    32581 gtcctaggcc tgcatgaagg acgtttccta ggatgacttc atcaaccatt tcaggcttta
    32641 cttgcgtttt atcaaggatt tttttcagta cagttgttcc aagttcaaca gcagagacac
    32701 ttttaaagga gcctccaaaa gctccgatag gagttcgtaa agcttcaacg ataactatgt
    32761 ttttcataaa ataaacatcc tttcagtttt agaaagcgtt ttctatatct ctaagataac
    32821 aagaaaccgc tcaaaataaa aatatagaat ttttataagc atataaattt ttttgataga
    32881 tttggcaata gcaattaaaa atcacttatg tcataatgga attaatacta tcggaaaaaa
    32941 gactaataga caaggggata accatttgga tattaaacaa attcgttatt ttatcgcaat
    33001 cgttgaaaat cattttaact tgaaccaggc ggcggaactg ttgtatgtgt cgcagccgac
    33061 acttagcatg atgatcaatg attttgaaaa aagggaaaat gttaagctct tcaaacgaaa
    33121 aagaggtcgt attattgggt taacctatct tggtgataat tattataagg acgctcaaaa
    33181 ggttctcagt ctctatgatg acatgttttt gaaattgcat gatcacagta aagggttaaa
    33241 gggaagtatc aatattggta ttcctcctct tattttatca gttgttttct cagaagtaat
    33301 gccaaaactg attttagaaa atccgggaat tcaattcaat cttaaggaga ttggtgctta
    33361 ccaactaaaa aatgaactac tcgtgggaaa tgttgacgtc gcagtcttgt tatccccaac
    33421 aggcatcgct gataatttgg ttgagactta tgaaatccag agatcagaat tatctgtatg
    33481 cctgtctcca cgccatcgtt tagcttctaa aaaagttatt cagtgggaag atttaacaga
    33541 tgaacaactt gccctatttg atcctagttt catggttcac catttagtgc ttgaagcttg
    33601 cgagcgtcac caagtcagac ctaatattat tttgacgtcc tcttcctggg attttatgct
    33661 taattctacc aagattaatc acaacgtctt aactatttgt cccaaaccta ttacagaatt
    33721 ataccaattc aaggacatta agtgtattcc aatggaacgt cccatttctt ggcgtgttgt
    33781 cttaacacgc ctccggaaaa aaagttattc tgaaatagaa gcctacatca tggacgactt
    33841 gctacagtct ttttttaagt agggttctca actacttggc ccgaatgtta atttttttaa
    33901 aaatgaattg gaattgtgta aacgctcaat ttatgataaa ctaagagatg gctttctatt
    33961 aatgaaatct agaatatatt gaggtacaaa catggttaat attattttat taattgtttc
    34021 tgccctcatt ggtttaatat taggttatgc acttatttcg attagactca agtctgcgaa
    34081 ggaagctgca gagttgactc ttttaaacgc tgaacaagaa gctgttgata ttcgtggcaa
    34141 agcagaagta gatgctgaac acatcaaaaa aacagctaaa cgtgaaagta aagcaaatcg
    34201 taaagaatta cttttagaag caaaagaaga ggcaagaaaa tatcgtgaag agattgaaca
    34261 agaatttaag tctgaaagac aagagcttaa acaactcgag acacgcttag cggagcgctc
    34321 cttaactctt gaccgtaaag atgaaaacct atcaagtaaa gaaaaggtac tagatagtaa
    34381 agaacaaagt ctgaccgata aatctaaaca cattgatgag cggcaacttc aagtggaaaa
    34441 acttgaagag gagaaaaaag cagaactgga aaaagttgct gcgatgacga ttgcagaagc
    34501 gcgtgaagtg attttaatgg agacggaaaa caaactgacc catgaaattg cgacgcgcat
    34561 tcgagatgcc gaacgtgaca tcaaggaccg aacagttaaa acagccaagg acttgttagc
    34621 gcaagccatg caacgccttg ctggtgagta tgtgactgaa caaactatta ccagtgtcca
    34681 tctcccagac gacaacatga agggccgaat tattggacgt gaaggccgta atattcgtac
    34741 tttagagagc ttgactggca ttgacgttat tattgacgat actcctgaag ttgttatctt
    34801 atcaggattt gatcctattc gacgtgaaat tgctcgtatg accttggaat ctctgattgc
    34861 tgatggtcgc atccatccag ctcgtatcga ggaattggtt gagaaaaatc gtcttgaaat
    34921 ggataatcgt attcgtgagt acggtgaagc tgcagcctat gagattggtg caccaaacct
    34981 tcatcctgat ttgattaaaa tcatgggacg cctgcaattc cgtacctcgt ttggtcaaaa
    35041 tgtcctacgt cactctgttg aggttggtaa gttagctggt attttagctg gtgagttagg
    35101 tgaaaatgtt gctcttgccc gccgtgctgg tttcttgcac gatatgggta aagctattga
    35161 ccgtgaggtt gaaggtagtc acgttgagat tggaatggaa tttgcacgta aatacaaaga
    35221 acatccagtt gttgtcaaca ctattgctag ccaccacgga gatgtggagc cagattctgt
    35281 gatcgctgtg ctagtagctg cagcagacgc tctcagttcg gctcgtccag gcgctcgtaa
    35341 tgagtcaatg gagaattaca tcaagcgtct tcgtgattta gaagaaatcg cgacaagttt
    35401 tgatggggta caaaatagtt ttgcgctaca agctggacgt gagattcgta ttatggttca
    35461 acctgaaaaa atttcagatg atcaggttgt cattttgtcg cataaagtaa gagaaaaaat
    35521 tgaaaacaat ctagattacc caggaaatat taaagtaact gttattcgtg agatgagagc
    35581 ggttgattat gccaagtaga aaaagaggaa ttatcctctt tttctttatg acttgccttt
    35641 gaaaatgttc ttgaaaaaga ctagcctttt tgataaacta ttaaaaagca actaataagg
    35701 agaatacaat gtctgaacgc ggtttgttaa tcgtcttttc tggcccttca ggtgtcggaa
    35761 aaggaacggt aagacaagaa attttttcaa cgccagatca taaatttgaa tattcggttt
    35821 caatgacgac tcgtccgcaa agaccgggcg aggttgatgg ggttgattat ttcttccgca
    35881 cacgtgaaga atttgaagaa ctcattaaaa ctggtcaaat gctagagtat gctgaatatg
    35941 ttggtaatta ctatggcacc cctttaactt atgttaatga gactcttgat aagggaattg
    36001 atgtcttttt agaaattgaa gttcaaggag ctcttcaggt taagtcaaaa gtaccagatg
    36061 gtgtttttgt ttttttaaca ccaccagatt tagatgaatt agaagaccgc ctggttggtc
    36121 gtggtacaga tagtcaagaa gtcatagctc aacgtattga aagagcaaaa gaagaaattg
    36181 cccttatgcg cgaatacgat tatgcagttg ttaatgatga agttgccttg gcagctgagc
    36241 gggttaagcg tatcattgag acagaacact ttcgtgtgga gcgcgtgatt ggtcgttatg
    36301 ataaaatgat taaaataaca aaaaaaacct ttaaagctaa atagaaaaga gtaagcatta
    36361 tgatgttaaa accttccatt gataccttat tagataaagt atcatccaag tattcacttg
    36421 tgattttaca agccaaacgt gcccatgaac tagaagctgg tgccactcca actcaagaat
    36481 ttaaatcagt gaagtcaaca cttcaggcac ttgaagaaat tgaatcagga aacgttgtga
    36541 ttcacccaga tccttcagct aaacgtgaag ctgtccgtgc taagattgag gcagaacgct
    36601 tggccaaaga ggaagaggaa cgtaaaatca aagaacaaat tgctaaagaa aaagaagaag
    36661 aaggagaaaa aatctaaggt ttcagaaatc ttagattttt tcatatttag tacgatgtcc
    36721 atgacagaaa aggagaagca aatggaaaaa gtagctcatg tgattgtaga tattccattg
    36781 atgcaaacgg acaagccatt ttcttatggt attccaaaag agttagtttc tctcgtgcag
    36841 cttggttctc gtgtgcatgt tccttttgga aaagggaatc gtttgttgca aggctttatt
    36901 attggttttg gccaagaaga ttcaagctct cttaaactga ttcagaccgt tttagatcct
    36961 gagccagtcc taaaccaaga acaattgacc cttgctgatc agcttcgaaa aacagttttt
    37021 tcttataaaa tcacgctctt aaaagcaatg attcctaatc ttcttaactc taactatgat
    37081 aaagtgctaa ggccagagtc aggtctaaaa aagcctgata gagactttct ttttgaagga
    37141 aaaccatctg tcttatattc taccttagac cgcgagaagg aaaaaatagc tcttaaggcc
    37201 atacaagctg ggcatattac tgttagttat ttagccaaag acaagaaaaa cttaaagaca
    37261 gaaaaatatt atcacgtcga cttagacgcc ttagcggtac atcccatctc tagccgtgcc
    37321 aaaaagcgtc aattattaaa agactatctg ctaacccata cgaaggaagc taaacttgca
    37381 acgctttatc aagccttttc tagagatgtg gtggcttact ttgtgacaaa tcacttaatt
    37441 cgtattgacg agcgtcaaat tgatcgcagt gagccctatt ttgaccagat caaaccatct
    37501 tcttttttaa ccttaaatga acagcaagcg tcagctgtta ctgaaattgt tgagcaaatt
    37561 gggaaaccga gtaaaccttt tttgattgaa gggattacag gttcgggcaa gacagaagtt
    37621 tatcttcata tcatcgaagc ggttttaaaa caggataaga cagccattgt tttagtacca
    37681 gaaatttcgt tgactcctca gatgacctct cgttttattt cccgtttcgg aaagcaagtg
    37741 gctattatgc attcaggctt atcagatggt gaaaagtttg atgagtggcg caagataaaa
    37801 acaggacagg ctaaggttgt ggttggtgcc cgctctgcta ttttctcccc actagagcgg
    37861 attggtgcaa ttattattga tgaggagcat gaatcaacct ataaacaaga aagcaaccct
    37921 atataccatg ccagagaggt tgccctgctc agagctaaac accatcaagc agttgtggtt
    37981 atgggctctg ctacgccaag tattgaaagc cgagcaaggg ctagtaaggg tgtctatcat
    38041 tttattcaat taacgcaaag agcaaaccct cttgctaaga ttccagaagt aacgattgtt
    38101 gattttcgtg attatattgg acagcaagca gttagtaatt ttaccccata tttgattgat
    38161 aagattaaag aacgtttggt taaaaaagaa caagttgtct taatgttaaa tagacgtggc
    38221 tattctagtt ttgtgatgtg tcgggactgt ggttatgtgg acaaatgtcc caactgtgat
    38281 atctctttaa cccttcacat ggatactaaa actatgaatt gccattactg tgggtttcaa
    38341 aaacctatcc caattacttg tcctgagtgt catagcaata gtatccgcta ttatggcact
    38401 ggaactcaaa aagcttttga tgaattgcaa ggggttattc cagaagctaa gatcttgaga
    38461 atggatgttg acaccacacg aaaaaaaaga agtcacaaaa ccatactaga tagttttggt
    38521 cgccaggaag cagatatttt gttagggacg caaatgattg ccaaaggact ggattttcca
    38581 aatgtgactt tagttggggt actaaatgca gatacctcct taaatttgcc ggattttcga
    38641 gcgtcagaaa aaacgtttca attgttaaca caggttgctg gtcgggcagg ccgtgcccat
    38701 aagccaggag aagtcttgat tcaaacttat aatcccgatc actatgctat tcaattagct
    38761 aagaaacaag attttgaagc cttttaccgt tatgaaatgg cgattcgccg tcagatggct
    38821 tatccccctt actactttac agtgggtatt acgctttcgc atcgtttaga agcatcggtt
    38881 gtaaaaaaag cttatcaagt tacagaactg ctaaagagtc acttatcgga taatattaaa
    38941 atattaggac cgactcctaa gccaattgct agaacacaca atttatacca ctatcaaatt
    39001 ttgttaaaat accgttttga agataaccta gaagagacgc tcaatcgtat tcttgattgg
    39061 agtcaagaag cagataatcg tcatttaaaa ctaattattg attgtgaacc gcaacaattt
    39121 ttataaggta aatcactaaa tctaggatga tcagttatga tataataaaa atacaaagag
    39181 gaaagtcatg ataaaattat tatttatggg aactccccaa ttttcagcaa ctgtattgaa
    39241 gggcttgcta gataatcctg cctatgagat tttaggagtg gttactcagc ctgatcgagc
    39301 tgttggacgc aaaaaagata ttaaggtaac acctgtaaag caattagctc ttgagcatgg
    39361 aatatcaatc tatcagccgg aaaaattatc aggctctcaa gaactcattg agattatggg
    39421 acttggtgca gatggtatta ttacagcagc atttggccaa tttttaccaa caatattact
    39481 tgattcagtt tcatttgcta ttaatgtaca tgcatcattg ttacctaaat atcgaggtgg
    39541 agcacctatc cattatgcta ttatgaatgg agataaagag gccggcgtta ctattatgga
    39601 aatgattaaa gaaatggatg caggtgacat ggtcgctaaa gcaagcactc caattcttga
    39661 aaccgataat gtaggtactc tttttgagaa attagccatc attggtcgag acttactttt
    39721 ggatagtttg ccagcttatc tttctggaga attaaaacct attcctcaag atcacagcca
    39781 agctactttt tcacctaata tctctccaga acaagaaaaa ttagattgga caatgtctga
    39841 tcaagaagtg ttcaatcata ttcgaggtat gaacccttgg ccggtagcgc atacgttttt
    39901 agaggggcaa cgtttaaaaa tttacgaagc tcaactagct gaaggagagg gattacctgg
    39961 acaagttatt gtcaaaacca aaaaatcttt ggtaatagct actggacaag gtgctttgtc
    40021 cttgatcgtt gtgcaaccgg ctggtaaacc taaaatgtca ataatagact ttttaaacgg
    40081 cattggtaga aaacttgaag taggggacat cattggcaga taattggaaa aaaagtacgc
    40141 gaggcaaagc cctccttgtc attgaagcta tttttgatca gggggcttac acaaacatag
    40201 cgcttaatca gcaactaagc aataaagctt tatctgctaa ggacagagct ctattaactg
    40261 agattgtata tggtaccgtt tcacgtaaaa ttagcttgga atggtattta gcccattatg
    40321 tcaaagaccg agataaattg gacaaatggg tttattatct ccttatgctc agtctttatc
    40381 aactgactta tttagataag ttaccagcgc atgccattgt taacgatgcg gttggtattg
    40441 ccaaaaatcg tggcaataaa aaaggtgcag agaagtttgt caatgctatt ttacgtcaat
    40501 tcaccagcca tcctctccca gatatggaaa caattaagcg tcgaaataag tattattcgg
    40561 tcaagtattc actgcctgtt tggttggtta aaaagttaga agaccaattt ggctccgaca
    40621 gagcagtggc tattatggag agtttatttg tgcgtagtaa ggctagtatt cgcgtgacgg
    40681 accctttgaa gttagaagaa gttgctgagg ctttagatgc agaacgttcc cttttatcag
    40741 caactggttt aaccaaagcg tcaggtcatt ttgcagccag tgattatttc acaaatgggg
    40801 acatcactat tcaagatgaa agcagtcagc ttgtagctcc tactttaaac attgacggtg
    40861 acgacataat tcttgatgcg tgtagcgctc cagggggcaa gacctctcat atagcatctt
    40921 acttaaaaac aggtaaagtt attgccttag atctctatga tcataaacta gagttggtga
    40981 aggaaaatgc taaccgctta ggagttgctg ataacattga gacaagaaaa ctagatgcca
    41041 gagaggttca tcgtcatttt gaaaaggata gctttgataa gattttggtg gatgctcctt
    41101 gctcaggaat tggtttgatt cgtcgaaaac ccgatatcaa atataataaa gaaagtcaag
    41161 attttaatgc tctacaggct atccagctag agatattgtc tagtgtttgt caaaccttgc
    41221 gtaaaggtgg tataataaca tacagtactt gcactatttt tgatgaggag aatcgtcaag
    41281 tcatcgaagc atttttacag agtcatccta attttgaaca agtaaaactg aaccatacac
    41341 aagcagatat tgtcaaggat ggttatctta ttatcacacc agaacaatac cagactgatg
    41401 gcttctttat tggacaagtc agacgagtct tgtagtattt taggaggaaa ctgactgagt
    41461 cagaaaaaac gtatgaagat ttcattaaaa acagacattg ggcaaaaacg ctcaaacaat
    41521 caagatttta tcaataagtt tgataataaa aaaggcatca ctttagtgat tttagcagac
    41581 ggtatgggtg gccacagagc tggaaatatt gccagtgaga tgacagtcac agacctggga
    41641 agagaatggg taaaaacaga cttcacagag ttaagtcaga ttagagattg gttatttgaa
    41701 actatccagt cagaaaatca acggatttat gatctaggcc aatcagaaga ctttaaagga
    41761 atgggaacga ctgttgaagc agtagcttta gttgaatcta gcgccattta tgctcatatt
    41821 ggtgattcac ggattggtct tgtccatgat gggcattata ccttattgac cagtgatcat
    41881 tctttagtga atgagttggt taaggcagga cagatcacag aagaagaagc tgctagccat
    41941 ccacaaagaa atattatcac tcaatctatt ggtcaagctt ccccagtaga gcctgattta
    42001 ggagtgaggg ttttggagcc aggggattat cttgtcatta acagtgatgg tctaaccaat
    42061 atgatttcaa atgatgaaat tgtgactatc ttgggcagta aggttagtct tgatgaaaaa
    42121 aaccaagaaa tgattgactt agctaaccta agaggaggcc tagataatat tacaatcgct
    42181 ttggttcaca acgaaagtga ggacgtcgaa tgattcagat tggcaaatta tttgctggtc
    42241 gttatcgcat tctaaaatct attggccgcg gtggtatggc ggatgtttat ttagcaaatg
    42301 acttgatctt ggataatgaa gacgttgcaa tcaaggtctt gcgtaccaat tatcaaacag
    42361 atcaggtagc agttgcgcgt ttccaacgag aagcgcgagc catggctgaa ttgaaccatc
    42421 ccaatattgt tgccatccgg gatataggtg aagaagacgg acagcaattt ttagtaatgg
    42481 aatatgtgga tggtgctgac ctaaagagat acattcaaaa tcatgctcca ttatctaata
    42541 atgaagtggt tagaattatg gaagaagtcc tttctgctat gactttagcc caccaaaaag
    42601 gaattgtaca cagagattta aaacctcaaa atatcctact aactaaggag ggtgttgtca
    42661 aagtaactga tttcggcatc gcagtagcct ttgcagaaac aagcttgaca caaactaatt
    42721 cgatgttagg cagtgttcat tacttgtctc cagaacaggc tcgcggctcc aaagcgacga
    42781 ttcaaagtga tatttatgcg atggggatta tgctctttga gatgttgaca ggccatatcc
    42841 cttatgatgg cgatagtgct gttacgattg ccttgcaaca ttttcaaaaa cctcttccat
    42901 ctattatcga ggagaaccac aatgtgccac aagctttgga gaatgttgtt attcgagcaa
    42961 cagccaagaa attaagtgat cgttacgggt caacctttga aatgagtcgt gacttaatga
    43021 cggcgcttag ttataatcgt agtcgggagc ataagattat ctttgaggat gttgaaagta
    43081 ccaaacccct ccccaaagtg gcctcaggtc ccaccgcttc tgtaaaattg tctcccccta
    43141 ccccaacagt gttaacacag gaaagtcgat tagatcaaac taatcaaaca gatgctttac
    43201 agccccccac caaaaagaaa aaaagtggtc gttttttagg tactttattc aaaattcttt
    43261 tttctttctt tattgtaggt gtagcactct ttacttatct tatactaact aaaccaactt
    43321 ctgtgaaagt gcctaatgta gcaggcacta gtcttaaagt tgccaaacaa gaactgtatg
    43381 atgttgggct aaaagtgggt aaaatcaggc aaattgagag tgatacggtt gctgagggaa
    43441 atgtagttag aacagatcct aaagcaggaa cagctaagag gcaaggctca agcattacgc
    43501 tttatgtgtc aattggaaac aaaggttttg acatggaaaa ctacaaagga ctagattatc
    43561 aagaagctat gaatagtttg atagaaactt atggtgttcc aaaatcaaaa atcaaaattg
    43621 agcgcattgt aactaatgaa tatcctgaaa atacagtcat cagtcaatcg ccaagtgcgg
    43681 gtgataaatt taatccaaac ggaaagtcta aaattacgct cagtgttgct gttagtgata
    43741 cgatcactat gcctatggta acagaatata gttatgcaga tgcagtcaat accttaacag
    43801 ctttaggtat agatgcatct agaataaaag cttatgtgcc aagctctagc tcagcaacgg
    43861 gctttgtgcc aattcattct cctagttcta aagctattgt cagtggtcaa tctccttact
    43921 atggaacgtc tttgagtctg tctgataaag gagagcttag tctttacctt tatccagaag
    43981 aaacacactc ttctagtagc tcatcgagtt caacgtcaag ttcaaacagt tcttcaacaa
    44041 atgatagtac tgcaccaggt agcaacactg aattaagccc atcagaaact actgctcaaa
    44101 caccttaaca aagaatagtt agtctcatgt tttactggca tgccactaac tattcttttt
    44161 aactactcgt catataaaga tgcaattttc caggaattct gataaaatac aaagaaataa
    44221 ggggaaacta atgaaaaaat ttcaattctt tttacttatc gagtgtatac tgctagctat
    44281 gggtatcatg acaatcttgg ataatgattt atcaagtttt atcctaattc tcgttcttat
    44341 cttattagca ttacgctttt ataaccaaga tagccgcaat aattttttgc taactgtcag
    44401 tttattgttt ctttttttaa ttttcatgct taatccctac attatcatgg ctgttctttt
    44461 ggggatagtt tacattttca ttaaccattt ttcacaagtc aaaaagaaga atcgctttgc
    44521 cttgattcgt ttcaaggaag aaaagattga agtgaataat accaagcatc aatggattgg
    44581 tactgctaat tatgaaagtg attattattg ttttgatgac attaacatca ttcgaatctc
    44641 aggaaatgac acggttgact taaccaatgt tattgtgaca ggaatggata atatcattgt
    44701 gatacgtaaa atttttggaa atacgactat attggtacct attgatgtca ctgttacttt
    44761 agatgttagt tccatatacg gaagcgttga tttttttaga tgtcagcaat atgatttgcg
    44821 caacgaatct attaagttaa aagaaacgga taaccaatcc cttaaaaaag tcaaaattat
    44881 cgttacaact attgccggaa atgttgaggt ggataggcga tgaaaaaacg ttactatgct
    44941 cttgtttggc tctactcaac cattaccatt ttatctattg tttttgtggt catggataat
    45001 ttaggaatca cttttaacta ccttcgcaac catttatggc aggttgaacg tctagggttt
    45061 tcgattttat tgttgattgt ttctgtgact ttattattgt tgttattgtg gattattatg
    45121 gatgataaca gtaagcgtaa catcaaccaa aatctaaaat atattctcaa taatcgacga
    45181 ctctatctag atgagacatc agaaatcaat actaatttaa gtcgactttc taaaaaaatg
    45241 tctcacctga ctgctaacat gcaaaagaaa gaaagtgctt atattcttga tagccaagaa
    45301 gttgtaaaac aagagcgcaa acgaattgca agagatttac atgacacagt cagtcaagag
    45361 ctattcgctt cgtcattgat tttatcagga atttcgatga gtttggaaca actggacaaa
    45421 acacaattac aaacacagtt aacaacggtt gaagcaatgt tgcaaaatgc tcaaaatgat
    45481 ctacgcattc tccttttgca tcttagacct accgagctag ctaatcggac tttatctgag
    45541 ggccttcata tgattcttaa ggaattaaca gataaaagtg atattgaagt catttataag
    45601 gaaaccattg ctcagcttcc caaaacaatg gaagataatc tttttagaat tgcccaagaa
    45661 ttcattagca acacgttaaa acatgctaaa gctagtcgaa ttgaagttta tctcaatcaa
    45721 acctcaacag aattacaatt gaagatgatt gatgatggtg taggatttga tatggatcag
    45781 gtaagggatt tgagttatgg tctgaagaat attgaagacc gtgtcaatga tttagcagga
    45841 aacctacatt taattagtca aaaaggcaaa ggagtttcca tggatattag actgccgata
    45901 gtgaagggag atgacgatga gtaagataaa agtgatattg gtcgatgatc atgaaatggt
    45961 ccgcatggga ctcaagagtt ttttgaattt acaagctgat attgatgtcg ttggtgaggc
    46021 ctctaatgga cgtgaagggg ttgatttggc attggctttg aagccagatg ttttggttat
    46081 ggatctagtg atgccagagt taggcggtgt tgaggcaact ttagaagtcc taaaaaaatg
    46141 gaaagaggct aaggtacttg tgttaacttc ctatctagat aatgaaaaga tataccctgt
    46201 cattgatgca ggagcgaagg gttatatgtt aaaaacatcg agtgcggctg aaattttaaa
    46261 tgccattcgc aaggtttcaa agggagagtt agctattgaa acagaagttg acaaaaaaat
    46321 taaggcgcat gatcaacacc ctgacttgca tgaggaacta acagcgcgtg agtatgatat
    46381 tttacacctt ttagctaaag ggtatgataa tcagaccatc gctgatgaac tctttatttc
    46441 cttaaaaacc gtcaaaacac atgtgtccaa tattctagcc aagttagaag ttgatgaccg
    46501 aacccaagcg gttgtctatg cttttcgaca ccatttagtc ccccaagacg ataattaatg
    46561 ctataatata gggtatagca aattggagga aagtatggac gcaaaactaa aatacaaagc
    46621 taaaaaaatc aaaatggtgt tctttgatat tgatgatacc ttgagggtca aagatacggg
    46681 ttatatgcct gagtcgattc aaagagtatt taaggctttg aaggcaaaag gcatcttggt
    46741 tggtattgct tcaggtcgcg ctcgttacgg tgttccacaa gaagttcaag atttacatgc
    46801 tgactattgt gtcaaattaa atggagctta tgtcaaagac gatgctaaaa ctattatttt
    46861 ccaagctccg attccagcag atgttgttgt ggcctataaa aaatgggcgg atgatatggg
    46921 cattttttat ggaatggcgg gtcgtcatga agcggtgttg tccgctcgaa atgacatgat
    46981 tagcaatgct attgataatg tctacgctca actagaggtc tgtccggatt ataatgagta
    47041 tcatgatgtt taccagatgt ggactttcga ggacaaggga gatggcttgc agttgcctgc
    47101 tgaattagca gagcaccttc gtttggtcag atggcacgat aactcatcag atgttgtctt
    47161 gaaaggtacg tcaaaagcgc taggtgtttc aaaagtagtt gaccatttag gattaaaacc
    47221 tgaaaacatt ttggtgtttg gtgatgaact aaacgactta gagttatttg actatgctgg
    47281 tatcagtatt gcaatgggag tatcacaccc acgtttgcaa gaaaaagcag atgttatcac
    47341 aaaaaaagtt gaagaagatg gcattttata tgccttggag gaattaggat tgattgacaa
    47401 agaattacag tttccacaat tggatttggc aaaccataaa ggaccaaaag caaccattaa
    47461 aacaaaccat ggcgatatga ccctggtctt gttcccagag catgccccta agacggttgc
    47521 taacttctta ggattagcta aagaagggta ctatgatggg attatcttcc accgtattat
    47581 tcctgaattt atgattcaag ggggcgatcc aacaggaaca ggaatgggtg gacaatccat
    47641 ctatggtgaa agttttgaag atgaattttc ggatgaactt tataatctcc gtggggcctt
    47701 gtcgatggct aatgcgggac caaatactaa cggcagtcag tactttattg ttcaaaatag
    47761 taaggttcct tatgccaaaa aagaactaga acgtggtggt tggccggctc caattgcagc
    47821 ttcttacgct gaaaatggtg gaactcctca ccttgatcgt cgtcatacgg tctttggtca
    47881 gcttgtgaac gaaacttcat tccaagtttt ggatttgatt gctggcgttg aaactggcgc
    47941 acaggataaa cctaaagaag acgttatcat tgaaacaatc gaggtatttg actaatgaaa
    48001 attggcgaca aactgcatgg gaccattaca ggaattaaac catacggtgc ctttgttgcc
    48061 cttgacaatg ggacaacagg tctcattcat atttcagaaa taaaaacggg atttattgat
    48121 gatattgatc aattattggc tataggcaac caggttttag tacaagtaat tgatattgat
    48181 gaatatagta aaaaggcaag tttatctatg cggaccttag cagaagaaaa acagcatttt
    48241 ttccatcgtc atcgttattc caacagtcgg cacaagattg gctttaggcc acttgaagag
    48301 cagttacctc agtggattga agaaagccta cagtttttaa aaaagaacac taaaaagagt
    48361 ctggaacctt agtagttcca aacccttttt tatttcgtct caattactgg tacatcatag
    48421 agttcagtcg ataaatagcg ttcgccatta tctggtaaaa tagttaatac atgtttgcct
    48481 tttcctaact gtttagcgac ttcaatagcg gcgtaaagag cagctccaga agaaatccca
    48541 accaggaagc cttccttagc tcctgttcgt cgagcagttt ctaaagcatc tttcgattta
    48601 acacggataa tttggtcata ggctttggta tctaacgtgt ttgggataaa tccagctgat
    48661 ataccttgga ttttatgtgg tccaggctct tgaccagata agacagcaga ttcttcagct
    48721 tcaacagcat agatagcagt ttcagggcta gcttttttca agacatgtga aacaccagaa
    48781 agtgttcctc cagtaccaac accagatacg aatgcatcta aagaaatctc cttaaaagct
    48841 tccaaaattt cttgagctgt tgttttttca tggatgcttg gattggcagg gttattaaat
    48901 tgcataggca tccaagcacc tagttctatt gctaaagttt cagcttttgc aatagcccct
    48961 ttcatacctt ctgctccagg tgttaagaca agctctgcac cataagcctg aatgatttgt
    49021 cgtctttcca agctcatcgt ttcgggcata acaataatga ctcgataccc tttagcagca
    49081 cctacccatg caagaccaat acctgtatta ccgcttgttg gttcgataat aacgtcacca
    49141 ggacttatca gaccttcagc ttcagcagct tcaatcatcg ataaagcaat acgatcttta
    49201 acagaagatc ctgggttaaa agcttctaat tttacataaa cgtcagcagc ttcgtttgga
    49261 attaaacggt taagtttgat aataggtgtt tgacctacta attctgttat agttttgtaa
    49321 attttagtca tagtttagcc tcttttcttg atacaaaata aatacgctgt gtatttaagt
    49381 ataaggagag atattattaa agtaaaatac agatttacta tcactctgat aataaagcca
    49441 tatcactttt gttgatgatt aatcacaggg gaattcaata actttggatc cgattttctc
    49501 acagcttatc tgaccatgat aataatttgt taaagtatca atgagatttt ctacacgttc
    49561 agtatcacaa taaagtgttg tctttatcgt gtctgaaaac ttagtttctg tttcggttaa
    49621 agccaattga tctagcaagt tagaatatag ttgatattgg ggataagaaa gtgtgatttc
    49681 tagtcctatc tgctgtttaa cttcaatgat gccaaatcgt ttaatagctg ttgcggtcat
    49741 gctagagtat gctctgatta acccacctgt tcctaattta ataccaccaa agtaacgcgt
    49801 taccacaact actacatttg ttaaacactg tttttctaac acagaaagga taggtattcc
    49861 agcagttcct gaaggttcac catcatcact tgagcgcttg atctgactgt tgttaccgat
    49921 aatcatcgca aagcaggaat gattagcttt gtaatgttct tttttgatag cattaacaaa
    49981 attcttacca tcttcttcag tgctcactcg tttgatatga caaatgaaac gagatttttt
    50041 aatactttct tcgaaaaaac cactggcttt gattgtctta aaatgttcca taaaaaaatt
    50101 gtacaagaaa agataaaaat tagcaaaaaa agcgaataat aaagtatgga gtctattgaa
    50161 aatagttatg ggcggttgtt gctagaaagc cagttaccag attcagcaag gcaacttgct
    50221 caacctttaa aaagtgtagt aatatcgaga ggaaaaatga tttgtcaacg ttgtcactat
    50281 cagcttgatg aagaagcacg attgccaagt ggagcctatt attgccgatt ttgtcttgtc
    50341 tttggacgaa atcaatcaga taaattgatc tatgctatcc cacctatgca ttttccaaaa
    50401 ggtaattatc tggtttggag cggtcaacta actgcttatc aagagatgat ttcccaacag
    50461 ttattaatca atatgcaaaa tcaaaaaaca acattagttc atgctgtaac tggtgcagga
    50521 aaaacagaaa tgatttatgc tgcgattgag gcggtaatta acacaggtgg ctgggtttgc
    50581 attgccagcc caagagtaga tgtttgtgta gaggtggcta ctcgtttatc ccaagccttc
    50641 tcctgcagca tctgtttaat gcacgcagag tctcttcctt atcaaagagc tcctattata
    50701 gtagccacaa cgcatcagct gctaaaattt cacaaggctt ttgatctctt aattattgat
    50761 gaagtagacg cattcccttt tgtaaataat attcaacttc attatgcagc aagtcaggct
    50821 ttaaaagaag gtggcgcaaa gattttatta actgcaactt caactagaac tttagaaaga
    50881 aaggtaaaca agggagaagt agtcaagctg acattggcga gacgctttca taataggcca
    50941 ttagttattc cgaaatttat aagaagtttt aatctattta aaatgataca tcggcaaaaa
    51001 cttcctccta aaattttaaa atacttaaaa aaacaaagaa aaacaggcta tcccctttta
    51061 atttttctac ccactattat aatggcagaa tctgttacag caatcttaaa agagttattg
    51121 cccgccgaac aaatagcttg tgtttctagt caatcacaaa acaggaaaga aggtatcaca
    51181 gcttttcgtc aagggaaaaa aacgatttta attacaacaa caattttaga aaggggtgtg
    51241 acatttcccc aaattgatgt ttttgttctt gggtctcatc atcgtgtcta tagttcccaa
    51301 agtcttgttc aaattgctgg acgagttgga agatctatag acagaccaga cggaacgtta
    51361 tatttctttc atgaaggtat cagtaaagca atgctactag caaaaaaaga gattaaagaa
    51421 atgaattata aagggtattc gcatgatctg tctactatgt caacaaatta gtcaaacacc
    51481 aataagtatt acagaaatca tctttttaag gcgtatctct tcaccgattt gtcaacaatg
    51541 tcaaaaaagc tttcaaaaga taggaaaaag tgtttgtgcg acatgttgtg caaactcaga
    51601 tataatagct tgtcaagatt gtctaaaatg ggaaaacaaa ggatacaatg taaatcatag
    51661 aagcttatat tgttataatg ctgctatgaa agcatacttc agtcaatata agtttcaagg
    51721 agactattta ttaagaaaag tttttgcagt agaacttgcc gatgttatca ccaagtacta
    51781 taaaggctat atcccagtcc cggttcctgt aagtctcggt tgttttcgag aaagacaatt
    51841 taatcaagtg agcgctattc ttgaggcagc taatgttagc tacctttctc tttttgaaaa
    51901 gctagataat actcaccaat cttccagaac aaaaaaagag agattattag tagaaaaatc
    51961 ttatcgacta ctaaaagtat caaacattcc tgataaaatc cttatagtag atgatattta
    52021 tactactggt agtacaatta tcgctcttag aaaacaattg gctaaagtag caaatagtga
    52081 cattaaaagt ttgtcaattg cacgttaaaa cttgcaaatt ttcatgaaag cagtataata
    52141 gtattaaaga taaagtaagc gcttcaagcg cgagaaagag gtatcctatg attaagttca
    52201 gtattcgtgg agaaaatatc gaagtgacag aagctattcg cgattatgta gaatcaaagc
    52261 ttactaaaat cgaaaaatat tttgctaaag accaagaaat agatgcacgt gttaatttaa
    52321 aagtttatcg ggagagatct tcaaaagttg aggtaacgat cccattagat tcagtaaccc
    52381 ttcgtgctga agatgtttca caggatatgt atggctctat tgatttagtt gttgataaga
    52441 tcgaacgcca aattagaaaa aataaaacca aaattgctaa aaaacatcgc gaaaaggttc
    52501 caactggtca agtctttaca actgagtttg aagctgaaga agtcgatgag ataccagaag
    52561 tacaagttgt acgtactaaa aatgtgacat taaaaccaat ggatgttgaa gaagcgcgtt
    52621 tacagatgga actattggga catgatttct ttatctacac tgattctgaa gatgatgcaa
    52681 caaacatttt ataccgtcgc gaagatggaa acctaggatt aatagaagct aaatagttca
    52741 caactaaaac ctacagggat gattatacgt attttaaaag tgggaaaaag ctattcatgt
    52801 ttagaggtga catgatgaaa atgagattaa gtgatagata cgacagtcat tatgctaaca
    52861 aaagtatcta ttacagttcc tctttaagta aatcttacgt aaaattagtt tgaaaaaaga
    52921 ttagtcccaa ttctgggcta gaaattctca aaaaatatga aaaagcgcgt tttcagaata
    52981 taaagcgcgt tttttctttt tccatttaac aataaaaaac tcatgacgaa tatggtatca
    53041 taagagaatt tttacttttt aaaaaaaggt caaagacttt ctgacaccaa ataaaaatag
    53101 aattttttct aactaaaaat aatagcacaa tctttggcag cgatccgaat tgtttttcca
    53161 taaaagattt aagcacttac gtttgcttaa aatataggtt atgtgacgtg cgtgcaagat
    53221 cagattataa caaaatagtt ccaaataagc ctatcactga gaaagcatca cagaagggtt
    53281 aaactttttt tgtattagcg ttttatcagt acaacctaac acttattttt ataaaaaaat
    53341 aaaaaagcta ttgacaatct tatacaagat aacgtatact aataaagctg ttgtaaatat
    53401 ggtaaagcaa tagatgctat caggaaaaaa tgtgaa
//
LOCUS       DAUGOH010000009        52798 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUGOH010000009 DAUGOH010000000
VERSION     DAUGOH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52798
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.009"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..224)
                     /locus_tag="VH957_000554"
     CDS             complement(<1..224)
                     /locus_tag="VH957_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8558494.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLETIPNSGDGFPLKITINKELTGFKLSIT"
     gene            complement(214..1341)
                     /locus_tag="VH957_000555"
     CDS             complement(214..1341)
                     /locus_tag="VH957_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8558495.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     NTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            complement(1338..2318)
                     /locus_tag="VH957_000556"
     CDS             complement(1338..2318)
                     /locus_tag="VH957_000556"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8558496.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            complement(2458..3036)
                     /locus_tag="VH957_000557"
     CDS             complement(2458..3036)
                     /locus_tag="VH957_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEQ8558497.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFVNSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHITFKYAKSKVARCINTLKKFNDK"
     gene            3124..3795
                     /locus_tag="VH957_000558"
     CDS             3124..3795
                     /locus_tag="VH957_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8558498.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            3770..4606
                     /locus_tag="VH957_000559"
     CDS             3770..4606
                     /locus_tag="VH957_000559"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEQ8558499.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            4603..5508
                     /locus_tag="VH957_000560"
     CDS             4603..5508
                     /locus_tag="VH957_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8558500.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            5512..6507
                     /gene="pta"
                     /locus_tag="VH957_000561"
     CDS             5512..6507
                     /gene="pta"
                     /locus_tag="VH957_000561"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEQ8558501.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKETFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            6634..7389
                     /locus_tag="VH957_000562"
     CDS             6634..7389
                     /locus_tag="VH957_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEQ8558502.1"
                     /translation="MGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKVLET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGFDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEERVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(7583..8272)
                     /locus_tag="VH957_000563"
     CDS             complement(7583..8272)
                     /locus_tag="VH957_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEQ8558503.1"
                     /translation="MKNAISILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     QSNQLSTFQGIFSFHEHDIDFPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            8692..9420
                     /locus_tag="VH957_000564"
     CDS             8692..9420
                     /locus_tag="VH957_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558504.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNAPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWAPEEVRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVANLFGGDEHA"
     gene            9413..10939
                     /locus_tag="VH957_000565"
     CDS             9413..10939
                     /locus_tag="VH957_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEQ8558505.1"
                     /translation="MPSLFITFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGTAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITFL
                     VLLASYTPMVLSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAEEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKASLLTKHPELKGILNQLAGKITEKEMQDMNYKVSVKGADANKVARDYLLKAGLIQK
                     "
     gene            11217..12200
                     /gene="guaC"
                     /locus_tag="VH957_000566"
     CDS             11217..12200
                     /gene="guaC"
                     /locus_tag="VH957_000566"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEQ8558506.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAGQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAYEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVNGETFKEYYGSASAYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      12323..12418
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12505..13086
                     /locus_tag="VH957_000567"
     CDS             12505..13086
                     /locus_tag="VH957_000567"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEQ8558507.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            13086..14369
                     /locus_tag="VH957_000568"
     CDS             13086..14369
                     /locus_tag="VH957_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEQ8558508.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIVAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(14433..15371)
                     /locus_tag="VH957_000569"
     CDS             complement(14433..15371)
                     /locus_tag="VH957_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEQ8558509.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLVQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKIFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETDMLSLTIMAPSSFYCDIWTTRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(15424..15609)
                     /locus_tag="VH957_000570"
     CDS             complement(15424..15609)
                     /locus_tag="VH957_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEQ8558510.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            15747..16316
                     /locus_tag="VH957_000571"
     CDS             15747..16316
                     /locus_tag="VH957_000571"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEQ8558511.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            16351..17430
                     /gene="prfA"
                     /locus_tag="VH957_000572"
     CDS             16351..17430
                     /gene="prfA"
                     /locus_tag="VH957_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEQ8558512.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDLNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            17430..18269
                     /gene="prmC"
                     /locus_tag="VH957_000573"
     CDS             17430..18269
                     /gene="prmC"
                     /locus_tag="VH957_000573"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEQ8558513.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFSEIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            18253..18843
                     /locus_tag="VH957_000574"
     CDS             18253..18843
                     /locus_tag="VH957_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEQ8558514.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            18861..19313
                     /locus_tag="VH957_000575"
     CDS             18861..19313
                     /locus_tag="VH957_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8558515.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            19303..20559
                     /locus_tag="VH957_000576"
     CDS             19303..20559
                     /locus_tag="VH957_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEQ8558516.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAITDHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALVPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVN
                     HNQTVILEEVRQEVRQLTDAFPLYKK"
     gene            20566..21543
                     /locus_tag="VH957_000577"
     CDS             20566..21543
                     /locus_tag="VH957_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEQ8558517.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVGQVKEVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            21544..22143
                     /locus_tag="VH957_000578"
     CDS             21544..22143
                     /locus_tag="VH957_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEQ8558518.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIKHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            22153..23877
                     /locus_tag="VH957_000579"
     CDS             22153..23877
                     /locus_tag="VH957_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558519.1"
                     /translation="MKRLRPYLKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLISVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHIGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLDPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KEQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPINDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKVLKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGEQK"
     gene            23874..25601
                     /locus_tag="VH957_000580"
     CDS             23874..25601
                     /locus_tag="VH957_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558520.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVIIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DVGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            25842..27212
                     /locus_tag="VH957_000581"
     CDS             25842..27212
                     /locus_tag="VH957_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEQ8558521.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIELFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(27371..28354)
                     /locus_tag="VH957_000582"
     CDS             complement(27371..28354)
                     /locus_tag="VH957_000582"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEQ8558522.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIIDKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            28545..31031
                     /gene="gyrA"
                     /locus_tag="VH957_000583"
     CDS             28545..31031
                     /gene="gyrA"
                     /locus_tag="VH957_000583"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEQ8558523.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELISTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIDEINTDRENSISKNKDN"
     gene            31051..31800
                     /locus_tag="VH957_000584"
     CDS             31051..31800
                     /locus_tag="VH957_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEQ8558524.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            31883..32296
                     /locus_tag="VH957_000585"
     CDS             31883..32296
                     /locus_tag="VH957_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8558525.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            32910..33347
                     /locus_tag="VH957_000586"
     CDS             32910..33347
                     /locus_tag="VH957_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558526.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKNSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEEKWQDTKDAVEVYGGIAAE
                     TVEESLGQAKEKVEGIGEATSQTIQSKMEKLTSDKTDADDDEK"
     gene            complement(33397..34308)
                     /locus_tag="VH957_000587"
     CDS             complement(33397..34308)
                     /locus_tag="VH957_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8558527.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEVITPKG
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(34425..35075)
                     /locus_tag="VH957_000588"
     CDS             complement(34425..35075)
                     /locus_tag="VH957_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEQ8558528.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(35072..35512)
                     /locus_tag="VH957_000589"
     CDS             complement(35072..35512)
                     /locus_tag="VH957_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEQ8558529.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQAGSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLSQEVTQ"
     gene            35731..36579
                     /gene="ylqF"
                     /locus_tag="VH957_000590"
     CDS             35731..36579
                     /gene="ylqF"
                     /locus_tag="VH957_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEQ8558530.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFREYY
                     PNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GNMDAD"
     gene            36569..37360
                     /locus_tag="VH957_000591"
     CDS             36569..37360
                     /locus_tag="VH957_000591"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEQ8558531.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKA
                     IQAELAEEERLEAMLSYEKALYKKGYQAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKAKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            37425..38261
                     /gene="dprA"
                     /locus_tag="VH957_000592"
     CDS             37425..38261
                     /gene="dprA"
                     /locus_tag="VH957_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEQ8558532.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            38368..40497
                     /gene="topA"
                     /locus_tag="VH957_000593"
     CDS             38368..40497
                     /gene="topA"
                     /locus_tag="VH957_000593"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEQ8558533.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEQWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(40572..41456)
                     /locus_tag="VH957_000594"
                     /pseudo
     CDS             complement(40572..41456)
                     /locus_tag="VH957_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            41469..42014
                     /locus_tag="VH957_000595"
                     /pseudo
     CDS             41469..42014
                     /locus_tag="VH957_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            42029..43021
                     /locus_tag="VH957_000596"
     CDS             42029..43021
                     /locus_tag="VH957_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEQ8558534.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGRKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNS
                     DLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            43126..43791
                     /locus_tag="VH957_000597"
     CDS             43126..43791
                     /locus_tag="VH957_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEQ8558535.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     ADD"
     gene            43784..44499
                     /locus_tag="VH957_000598"
                     /pseudo
     CDS             43784..44499
                     /locus_tag="VH957_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
     gene            44645..45991
                     /gene="trmFO"
                     /locus_tag="VH957_000599"
     CDS             44645..45991
                     /gene="trmFO"
                     /locus_tag="VH957_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEQ8558536.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAKSVTAELENHPLIEVIRDEITEIPNDAITVIATGPLTSDALAEKIHAVNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            46144..47550
                     /locus_tag="VH957_000600"
     CDS             46144..47550
                     /locus_tag="VH957_000600"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEQ8558537.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQARQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            47593..47907
                     /locus_tag="VH957_000601"
     CDS             47593..47907
                     /locus_tag="VH957_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558538.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            47907..48257
                     /locus_tag="VH957_000602"
     CDS             47907..48257
                     /locus_tag="VH957_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ8558539.1"
                     /translation="MKRYEVTVNGQVYEVSLRELADGETVEVSQPAAPATEKEMNANA
                     AGGGIQVKTPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            48267..49397
                     /locus_tag="VH957_000603"
     CDS             48267..49397
                     /locus_tag="VH957_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8558540.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(49598..50482)
                     /gene="citG"
                     /locus_tag="VH957_000604"
     CDS             complement(49598..50482)
                     /gene="citG"
                     /locus_tag="VH957_000604"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEQ8558541.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(50475..51170)
                     /locus_tag="VH957_000605"
     CDS             complement(50475..51170)
                     /locus_tag="VH957_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8558542.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(51328..52731)
                     /locus_tag="VH957_000606"
     CDS             complement(51328..52731)
                     /locus_tag="VH957_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEQ8558543.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
BASE COUNT        16508 a         9388 c        10835 g        16067 t
ORIGIN      
        1 tcggtgatag ataatttaaa acctgtgagt tctttattaa tagtgatttt taaagggaaa
       61 ccatcccctg aattaggtat tgtttcgagt aaacgtatta attggtagtg ccctacttta
      121 gtttgactaa atgtagtatc tcttagggta tattttttaa tgtttggact gattgtataa
      181 aggtatttac agtctttaag cttaatttct ttttcaaaag ccatctgttc ctcctaaaat
      241 attttttaat gtttgagcta attgattaac atcttcaatg ctattttgat ctgaaaaact
      301 gatacgaatt gattctttta aacgagaaga gtcatcccca tagtacgcag ctaaaacatg
      361 acttggatta acagctccag cagtacaagc agaaccagtt gatactgcaa tgcctgctaa
      421 gtcaagttgt gttagtaaaa tagtattttg gtagcctaaa aatccaatat tgagaacatg
      481 aggaagataa tgagtacctt gattaatata gtagggtagt ccttctagga ggctaatcaa
      541 gtgatgacgt aaactaataa tgtgatcagt tgattggtca agacaagtca tagcatcagt
      601 caaagcttgt gccataccaa taatacctaa catattttca gtacttgcgc gtcgctttcc
      661 ttcttgatca cccccgtgaa gaagaggatc gattggttgt ccgttactgt ataaaaagcc
      721 gcatccttta ggaccatgaa atttgtgagc agaagcagat aaaaagtcaa tcccaagttc
      781 gctaggaata atcttgagtt tgccaacagc ttgaacggca tcaacatgaa aagcagcttg
      841 atggtctttg agcagattcc caatgtcctt aataggtaac aggtcacctg tttcgttatt
      901 ggcatacatt atgcttacca aaatggtgtc atctctcaag gcttgtttta agtcagataa
      961 atttatttgt ccattttgac aaggcaaata agtgacctca aaaccaaatc gctcttcgag
     1021 ataggccatg gtattgagca cagagtggtg ctcaatagta gttgtgatga gatgtttgcc
     1081 ctttgcttga tgagctaaag catagccttt tatggccata ttattgcttt cagttccacc
     1141 ggacgttact ataatttgct gttcacttgc ccccaagttt ctagcgatag cttgtcggca
     1201 ttcacgaagg attttattgg ctcggcgccc gtagaaatga atactagagg ggttaccaaa
     1261 gttatcttgc atagctgctg tcatcgccct aatcacatta ggactaagtg gtgtggtggc
     1321 ggcgttatca aagtaagtca tgcgttattt ttgcctttag gttgataaga aaaaagtgga
     1381 cttaagggtc ttctttcatg gatacgaata atagcttctg cgattaaatc actggcgcta
     1441 agataagtaa cgttttctgg cacacgattt ttagttttaa cagaatctgt aacgataatt
     1501 tctttgattg gagctgtttc taatacctca gcagctccac cagcaaataa gccatggcta
     1561 gcgaccgcgt aagtatcagt agcgcctgag cgttcaagaa ttttagcagc ttctgcaaag
     1621 gttttcccag tatttaaaat atcatcaatt aaaatggctt ttttaccaga aacatcacca
     1681 ataatataac cttgttcacg ttcagaatca tcttgtgcat agtcgataat agcaatcggg
     1741 gaatcaagat attcagccaa gcttctagca cgtttaattc cagaattttt agggctaacg
     1801 acaacaacat cagaacctga taagcctaat ttactgtaac gttctgcaaa aagagggact
     1861 gtaaagaggt tatccactgg aatatcaaaa aaaccttgta cctgaacagc atgtaagtca
     1921 agcgtcacta cacgatcaat accagcttta gtcaacatat tagctactag tttagcagta
     1981 atcggttcgc ggggcttagc gacacggtct tgacgagagt aaccaaagta tggcaataca
     2041 atattgacgg tattagcact tgcacgttta caagcatcaa tcatgatgag taattcccaa
     2101 agattatcat tgacaggaaa actagtggat tgaataatat agatatcatc tccacgcact
     2161 gtttcttcaa tattgatcat aatttctcca tcggaaaatt gacgtgaaga catttttcca
     2221 agagggattc cagcagcttt agcaattttt tcagcaattg gaagatttga tgtgagtgag
     2281 aacagtttga tttgcttgtc agcatatcgt tcggtcatga tagatttagc tccttaactt
     2341 caataaaatt gggtaaactg ttttattaat gagtcacatt acccaaaagt gtttaattga
     2401 catccctatt ttaacagaaa aacagaaaaa tttcagtttt tctgtcgctt ttagccatta
     2461 tttatcgttg aactttttta aggtattaat acaccgagct actttacttt tagcatattt
     2521 gaaagtaatg tgatgttcag ataaaaaaga atcaaaatca atctttcctt gaagagcgtc
     2581 acttacttct aattctaatt catagtcttt ggtattggca tataggttat agtctaaggc
     2641 caatttacct atcggtatca ctgtctcgcg acgaacggta gttaaattgc caaaagttac
     2701 cagtgcagat ggtttgatac cttttgaaat aataatatca agagcagttg attcaggaag
     2761 attcccatgt ttaatcatat cttttgcttg ttcaagaaaa agagggacat tgtactcacg
     2821 attccccact ttttctggca cttttagggt taattcggcg ctatttacaa atgttcgaat
     2881 acgtaatgac attttgttag cttttaaatc aaatgctttt gtatcaatat agtaattagt
     2941 ttgtgtaaca ggcgtcacat gtttcatttg agataaaaga cggttatact cattttttgt
     3001 aagtagagtt ttatattcga tttctaggtt agtcatggga aattcctttt aatttgtgct
     3061 ataataaatt gttatttcaa ttttatatta ttatcctggc tttgacaaga aaggagacaa
     3121 tagatgacct tagattggga agaattttta gatccttata tccaaacagt tggtgaatta
     3181 aaaataaaac tacggggtat tcgcaagcaa tatcgtaagc aaaatcgtta ttctccgatt
     3241 gaatttgtta cgggacgtgt taagtcaatt gaaagtatta aagaaaaaat gattttacgt
     3301 ggtgttattg aagaaaatat agcacaagat attcaagata ttgctggact acgtattatg
     3361 gttcagtttg ttgatgatgt ggaagaagtc ttagctctat tgcgtcaacg acaagacatg
     3421 acaattgttt atgaacgaga ttatattcgc aatatgaagt ccagtggcta caggtcttat
     3481 catgtggtgg ttgagtaccc tgttgatact attgaaggtc aaaaaaaggt cttagcggag
     3541 attcagattc gtactttggc aatgaacttt tgggcgacca ttgagcattc tttaaattat
     3601 aaatatggtg gagacttccc agaagaaatt aaaaagcgtc ttgaagtgac tgctaaaatt
     3661 gctttagaat tagacgaaga aatgcgtaag attcgagaag atattcggga ggctcaatta
     3721 ttgtttgacc ccgtgacacg aaatttaagt gatggtgtag gaaatagtga tgacacagat
     3781 gaattataca ggtaaggtaa agcgagttgc tattattgca aatggtaagt accaaagtaa
     3841 acgcgtcgcc tccaaacttt tctccgtatt taaagatgat cctgatttct atctttcaaa
     3901 gaaaaatccg gatattgtga tttctattgg cggagatggg atgctcttgt ctgcctttca
     3961 catgtatgaa aaagaattag ataaggtacg ttttgtagga atccacaccg gtcatcttgg
     4021 cttttatacc gattataggg attttgaagt tgataaattg attgataatt taagaaaaga
     4081 caagggagaa caaatctctt atcctatttt aaaagttgct attactttag atgatggtcg
     4141 tgtggttaaa gcgcgtgctt tgaatgaagc gacggttaag cgtattgaaa aaacgatggt
     4201 agcagatgtt attattaacc atgtcaaatt tgaaagcttc cgaggtgatg ggatttcagt
     4261 atcaaccccg acagggagca cagcctacaa taaatcttta ggtggtgctg tcttgcatcc
     4321 gacgattgaa gcgctgcaat tgacggaaat ttccagtctt aataaccgtg tctttagaac
     4381 cttgggctca tcaatcatta ttcccaaaaa agataagatt gagttagtgc caaaacgatt
     4441 aggaatttat accatttcca ttgataataa aacctatcag ttaaaaaatg tgacgaaggt
     4501 ggagtatttt atcgacgatg agaaaattca ttttgtttcc tctccgagtc atacgagctt
     4561 ttgggaaagg gtcaaggatg cctttattgg agaaattgac tcatgagatt tgaatttgta
     4621 gcagacaaac gaataaaagt aaaaaccctt ttaaaaagtc atgatgtctc taaaggacta
     4681 ttggctaaaa tcaaatataa gggtggtaat atattagtga atggtattga acaaaatgcc
     4741 atttatttat tgcaagtggg agatgttgtc accattgaca ttccaaacga agagcccttt
     4801 gaaaagcttg aagccatccc ttttgatttg gatattgttc acgaggatga tcattttttg
     4861 gtgattaata aacccattgg ctttgccagt attccaagtg ccatccattc caataccatt
     4921 gctaacttta tcaaggcata ttatgtggac aatcattacc tagaccaaca agtacatatc
     4981 gtgacccgtt tagacagaga tacgagtggc ttgatgttat ttgctaagca tggttatgct
     5041 catgcaaggt tggacaagca actccaaact cgctcaatag agaaacgtta ttttgctctg
     5101 gtttctggaa atgggacgtt gccagatgaa ggagatatta ttgctccaat tgggcgttca
     5161 aaagatagta ttattaccag ggcagttgac cctatgggca aatatgccaa gactagctat
     5221 aaggttgtgg cgcgctattc agaaaatgtg catttagtgg atatcaaatt gcatacagga
     5281 cgtacccatc aaatcagggt tcattttgcc catattggtt ttccactttt aggggatgac
     5341 ctttacggag gtcgtttgga cttaggaata acaaggcaag ccttacattg tcattatttg
     5401 aatttcaaag atccatttac agaaagtgat tgtagctatg caatacactt gacagatgac
     5461 tttgatagcg ttatcatagg tttacagaaa aaagatagag gttattaaag aatgagtatt
     5521 cgtagtttat tcggtggttt aagagaaaaa attcttggta aaaacatgaa gattgttttc
     5581 ccagaaggta atgatgagcg cgtcgtccgt gcagctgctc gtttgaaatt tgaaggactc
     5641 ttagaaccga ttatccttgg acagtcagaa gaggtacgca accttttgac aaaattaggc
     5701 ttcgctgatc aagactatac tatcattaat ccaaatgaat atgcggattt tgacaaaatg
     5761 aaagaaactt ttgttgacat ccgtaaagga aaagcaacgc ttgaagatgc tgataaaatg
     5821 cttcgtgatg tgaattactt tggtgttatg ttggttaaaa tgggattagc agatggaatg
     5881 gtatctggtg ctattcattc aacagctgat actgttcgtc cagcccttca aatcattaaa
     5941 accaaaccag gtatttcaag aacttcaggt gttttcttga tgaatcgtga aaatacgagt
     6001 gagcgttacg tgtttgctga ttgtgctatc aatattgacc caacagcaca agaattggca
     6061 gaaatcgctg ttaacacagc tgaaacagct aaaatctttg atattgatcc taaaattgct
     6121 atgttaagct tctcaacaaa aggttctggt aaagcgcctc aagttgataa ggtaagagaa
     6181 gcaacagaaa ttgctaaagg gttgaatcct gacttagctc ttgatggtga attgcagttt
     6241 gatgcagcct ttgttcctga aacggcagct atcaaagcac cagattcagc ggttgctggc
     6301 caagccaata cttttatttt ccctgactta caatctggaa atattggtta caaaattgca
     6361 caacgtttag gaatgtttga tgctattgga ccaatcttac aaggattgaa caaacctgtt
     6421 aatgatttat ctcgtggctc aagcgctgaa gatatttaca aattagctat tattacagca
     6481 gcacaagcta tcgaaagcca agggtaactt aagacccctt gatataggat tctaaccgct
     6541 aagtgatgtg ttagaagttg tcctaagact aattgacatt attaaaaacg agttggccag
     6601 accatctcgt tttttttgaa ggtgaggaaa tgtatgggaa atattgcctt agtaacaggg
     6661 gcttcagccg gttttggcag agccattgtc gaacacttaa ttgcagatgg gataaaggtt
     6721 attggtgctt ctcgtcgtct tgagaaactc aaggtcttag aaacgagctt tgggtcggac
     6781 aacttttacc ctttgcagat ggatgtcaca gataccaaag cgattgatga tgctttgaca
     6841 agtctaccaa atcagtggca agatattact attttagtga ataatgcagg cttagcattg
     6901 ggatttgata aggcttacga agccgatttt gagaattgga tgacgatgat taataccaat
     6961 attgttgggt tgatttatct cacacgtcaa ttattaccac atatggtctc caaagatgat
     7021 ggtattatta ttaatttagg gtcaaccgca gggacaattc cctatccggg agctaatatt
     7081 tatggggcta gcaaggcttt tgttaagcag ttctcactca atttacgagc tgatttagca
     7141 ggtagccata tacgtgtgac caatattgaa cccggtctat gtgaagggac agaattttca
     7201 aaggttcgct ttaatggtga tgaggaacgg gtgaaggcca tttatcaagg agcacatgcc
     7261 attcaacctc aagatattgc gtcgactgta tcatgggtga ttcatcagcc ccctcatgtt
     7321 aatgttaatc gtattgagct gatgccagtg tcgcaaagtt atggaccgca accagttagt
     7381 cgtgactagc aagggatgag tccataagaa taataatctt tagaaaaatg gtttactggt
     7441 atggattatt ctttataagt gagacttacc gatttagtca tcaaaaaaag caatcaagaa
     7501 gaaggttttg aggtcttcaa gcgttcatga ttgcttcttg tgcgttgatg atttaggctg
     7561 aactccctat ttaaaatcaa gtttagtgat ctaaaatgga agggcctgat gtgacatcgg
     7621 accagccaac aatggcttgt ccagtttctt ctaaatactg gtttaataac ggtttaatgt
     7681 cttgaacggt atccaaaact cccaccagct gaccttgagg atttttaaga gcttgataat
     7741 gctgcatgta aatatgatcc aatgaacccg aaggaagtag gaaggtttta caagggttat
     7801 ctgataaacg caattcagca agaatccaat cttctatttc tttatcagta gttggcaaaa
     7861 aacttccatt aaaagcatga ttatcgacta tgatgtttcc atttgcatca gataaccttg
     7921 cttgcaaagg aaggtactgt aaaaaatgtc catcaaattt ttggtaaaat ccagtgaggt
     7981 attggcttaa cgataagact gctgttgctt gatcaaagac actttctgtc actaaaaagc
     8041 cctgaccatg ttgagaagtt ttgaaataga gtgtaggaaa gtcaatgtca tgctcatgga
     8101 aactgaaaat tccttggaaa gtcgacaatt gatttgactg aatgttggct ttgctagtga
     8161 gaatagtcac ctcaaaaagg tgtgagaagt ggtgggaaag ctctctaata aacgtctctt
     8221 caagttggtt ttcaggtgtt aagagcgcta aaatggaaat ggcatttttc ataattgtat
     8281 gatagctgta ttttctagaa aagacaatta atctgcttat ctatcatcat aggcaagtct
     8341 aggatttttg ataaggtaat tttggagaga taggctgaca aagtgacctg tttttctata
     8401 agggggtaat agtctcatta tttgacttat agtgggaaac tttttataat ggtcaacaac
     8461 aaacgacaag aaaataatga gagaaaatgt ttttgagaat gggtagtttt taccttactg
     8521 agggtcccta agagtccctt taattagtag atgcgtttgt ctaaaaatgg aagtgcctgc
     8581 agtgattcct tgtagttact cagaacgttt tgagaaaaaa tgacagagag acaggttgaa
     8641 tgaactcatc agcctttatg ttgatgcttt aaccaatgaa ttggagagat aatgatacgt
     8701 tttaataatg tttctaaaac ttttggtcag acaaaggttt tgcaagagca gacctttcaa
     8761 attaatgacc gtgaattttt tgtgctggtt ggccccagcg gatcgggcaa gaccacactt
     8821 ttaaaaatga ttaattgcct tattgaacca agctctggag acattttact aaataacgcc
     8881 ccacagaaag agttagattt acgtgagatg aggctatcta ttggatacgt attgcagcaa
     8941 attgctcttt tccccaatct cacagtagct gaaaatattg cgattatccc tgagatgaag
     9001 cagtgggcac ctgaagaagt tagacaaaaa actgaagaat tattggataa ggtgggccta
     9061 cctgctaaag attatcttga tcgttaccca agtgatttat caggaggtga acagcaacgt
     9121 attggtattg tacgtgctat catttctcat cctaaaattc tattgatgga tgaaccattt
     9181 tcagccttag atcctatttc acgtaaacaa ttacaagagt taatgttgag tcttcacaag
     9241 gaatttgaca tgacgattgt atttgtgaca catgatattg atgaggctat taaattagga
     9301 gaccgcgtgg ctattttaaa tgagggagaa attgtgcaac tggatcgccc agaaatgatt
     9361 aagacccacc ctgctaatgc ttttgtggcc aatttatttg gaggtgatga gcatgcctag
     9421 tttgtttatc acctttcaaa accgttttaa tgaatggctg gcggctctgg gggaacacct
     9481 gcaaatttcc cttttatctc ttatgatcgc cttgctaata ggtgtgcctt tagcagccct
     9541 tctcagtcgc agcaaacgtt ggtcagacat tatgttacag gtaacaggtg tttttcaaac
     9601 cattccctca ctggctttgc ttggtctttt catcccttta atgggaattg gaacgttgcc
     9661 tgcagtgaca gctttagtta tctatgcgat ttttccgatt ttacagaaca ccatcacagg
     9721 gttaaatggt attgacccaa gtctcgtgga agcagggaca gcgtttggga tgaccaaatg
     9781 ggagcgattg aaaacatttg agattccaat tgccatgcct gtgattatgt caggtgtgcg
     9841 gacgtcagca gtcatgatta ttggcacagc tactttagct tccttgatag gagctggtgg
     9901 acttggctct ttcatcttat tggggattga tcgtaataat gctaacctga ttctgatagg
     9961 ggctatttct tcagctctgc tagctattat tttcaatagt ttgttacagt accttgagaa
    10021 agcttccttg cgacgaatta tgattagttt tggaatcacc tttcttgtct tgttggcatc
    10081 atatactcct atggtgctta gtcagttttc aaaaggaaaa gatacagtgg ttattgccgg
    10141 taaattggga gcagagcccg atattctgat taatctctat aaggaattaa ttgaagacca
    10201 atcagatata agcgttgagt tgaaatctaa ttttgggaaa actagcttct tatatgaagc
    10261 tcttaaatct ggagatattg atatctatcc tgaatttaca ggaaccataa catcaagtct
    10321 tttacgtgac aaaccacctt tgtctaatga ccctaagcag gtctatgagg atgctaaaaa
    10381 aggcattgct aagcaagata aactgaccct tcttaagccg tttgcttacc aaaatacgta
    10441 tgctgttgct atgccagaaa aattggcaga ggaatatcag attgaaacca tttctgattt
    10501 aaaagcgcat gctgatactt taaaggctgg ttttactctg gaatttaagg acagagcaga
    10561 tggctataag ggaatgcaat ctcaatatgg gttacagtta tctgtggcga cgatggagcc
    10621 agctcttcgt tatcaagcaa ttcaatcagg agatatccaa gtaacagatg cttactctac
    10681 ggatgctgaa attacgaaat accatttgaa agttttaaaa gatgataaac agttgtttcc
    10741 accttatcag ggagctcctt tgatgaaagc ctccttatta acaaaacatc cagaattaaa
    10801 aggcattctt aatcaattag cgggaaaaat tactgaaaaa gagatgcagg acatgaacta
    10861 caaggtatct gttaaaggag cagatgctaa taaggtcgct cgagattatc tgttgaaagc
    10921 gggattaatc cagaaataaa cagaaatgtt ggtccgtagg actggcattt tttcgtctct
    10981 tacgttcaag aagtaacaat tcataaatac aaaaaccgaa catttaaatt aaaaatagta
    11041 tttaaatttg acaaaaaata aacaatgaaa taaactataa aaggaaaggt aagtttttac
    11101 ctagcgatgc ctctaatcat cagaggccat aggaaggtca ttttgtataa aggacgtgga
    11161 gaagaagatg agaactgact tattttcttt catctgtgtc taaagaggag aaacttatgt
    11221 ttaatgacat ccctgtattt gattatgaag atattcaact gattcctaac aagtgcatta
    11281 ttactagtcg ttcacaagca gatacaagtg tgacactcgg aaaataccag ttcaagctac
    11341 cagttatccc agcaaatatg caaaccatta ttgatgaaac aattgctggg cagttggcaa
    11401 aagagggtta tttttatatt atgcatcgtt ttgatgaaga tagccgcaaa ccttttatca
    11461 agcgcatgca tgaacaaggc ttgattgcat caatctctgt tggggttaaa gcttacgaat
    11521 atgaatttgt gacttctttg aaagaggatg ctcctgagtt tattaccatt gatattgctc
    11581 atggtcatgc taacagtgtt attgatatga ttaagcatat caaaactgaa ttaccagaaa
    11641 catttgtcat tgctggaaat gttggtacgc cagaagctgt acgagaactc gaaaacgcag
    11701 gtgctgatgc tactaaagta ggcatcggtc caggcaaagt atgtatcact aaagtaaaaa
    11761 caggtttcgg tacaggtggt tggcagttag cagcactgcg ctggtgcgca aaggcagctc
    11821 gtaagcctat cattgctgat ggtgggattc gcacacatgg tgatatcgct aaatccatcc
    11881 gctttggagc tagtatggtc atgattggat cgctttttgc agggcatatt gaaagtcctg
    11941 gaaaaacagt agaagtgaat ggtgaaacgt ttaaagaata ttatggctcg gcgtcagcat
    12001 atcaaaaagg cgagcataaa aatgtagaag gcaaaaaaat cttattgcct acaaaaggtc
    12061 acttatcaga taccctgacc gaaatgcaac aggatttgca atcgtccatt tcttacgcgg
    12121 gtggtaaaga tttagacagt ttgcgtcatg ttgattatgt tatcgtcaaa aattctattt
    12181 ggaatggtga ttccatttaa atgatatgga gttagctagg accagtaaag aattttttag
    12241 cttaatgctg gagatgcttt tatcatatct ctgtaggtat tgaaaaaaat aagaaacatg
    12301 gtaaaatagt aaattatcat aatgaattca ataatgacat acttatttat gctgtgaatt
    12361 ggcgcagcgt ctctacaaga caccttaatg tctaacaata agtaagcttt taggcttgct
    12421 tggtttttaa ccttgcaaag tgagaaactc ttatagtttc tggctttgcg gcaggctttt
    12481 tctatttgaa tcaaaaggag atttatgcag ttacttgaag aacgcatctt aacagatggc
    12541 aatattctag gagagaatat tctaaaggta gataattttt taactcatca agttgattac
    12601 cggttgatga aagcaattgg taaagtgttt gctcaaaaat atgctgaggc tggcattaca
    12661 aaagtggtta caatcgaagc ttcaggtatt gcaccagccg tatacgctgc agaagcaatg
    12721 gatgttccta tgatttttgc gaaaaaacat aaaaacatta ccatgacaga aggcattttg
    12781 acagcagaag tttattcttt cactaaacaa gttacgagca cggtgtctat cgctggtaaa
    12841 ttcctatcta aagaagacaa ggttttgatt attgatgact ttttagctaa tggtcaggca
    12901 gccaaaggct tgatcgagat tattggtcaa gcaggggcac aagtcgtcgg cgttggtatt
    12961 gtgattgaga aatctttcca agatggtcgt cgattgattg aagatatggg cattgaagtg
    13021 acctcattag cccgtattaa aaactttgaa aatggtaatc taaacttctt ggaggctgac
    13081 gcataatgac acattcaaca aagcaggaac attctcactc gcaatcagct gtccttggct
    13141 tacagcatgt gctttcgatg tatgccggat ctattttagt accaattatg attgcaggtg
    13201 ctttaggtta ttccgctaga gagttgactt acctgatttc gacagatatt ttcatgtgtg
    13261 gtgtggctac tttcttacag ttaaagttaa ccaagcatac gggagtggga ttaccagttg
    13321 ttttaggatg tgcttttcaa tcagtggcac ctctatccat tattggagcg cagcaaggtt
    13381 caggtgccat gtttggagcc ctcattgcgt caggaattta tgtcatttta gtggcaggta
    13441 ttttttctaa gattgctcgt ttcttcccac caattgttac aggatcggtc attaccgtta
    13501 ttggcttaag tctcgtaggt gttgctatgg ggaatatggg agataacgtc aaagagccta
    13561 cggcacaaag catgatgcta tcattgttga cgattgtcat tattctttta gtccaaaaat
    13621 ttaccaaagg ttttgtgaaa tccatttcca ttttgattgg gcttgtagcg ggaactttgg
    13681 tttcagccat gatgggatta gtagatacaa ctcctgttgt agaggcttct tggattcatg
    13741 tgccaacccc attttatttt ggcatgccaa cttttgaaat cacttctatt gtgatgatgt
    13801 gtatcatcgc aacggtttct atggttgaat caacaggtgt ctacttagcg ctttcagatt
    13861 tgactaatga tcaattagat gaaaaacgtt tgcgcaatgg ttatcgctca gaagggatcg
    13921 cagtctttct cggtgggtta tttaatacct tcccttacac tggtttttct caaaacgttg
    13981 gacttgtcca aatctcaggt attaaaaccc gtcgtccgat ttactacgca gcaggtatcc
    14041 ttgtggtcat tggtctactc cctaaatttg gagcaatggc acaaatgatt ccaagcccag
    14101 ttcttggtgg agccatgctt gttctctttg gtatggttgc tcttcaagga atgcaaatgc
    14161 ttaatcgtgt tgatttccaa aagaacgagt ataattttat tattgttgcc gtttccatct
    14221 cagcaggttt aggctttaat ggcactaatc tttttgccag cttaccagag acagctcaaa
    14281 tgttcttaac gaatggtatt gtgattgcca ctttgacatc tgttgtctta aatttagttt
    14341 taaatggcaa agacaaacaa gatgaataat taaaaaacgg ctaattgagt cgttttttct
    14401 gtgatcagtt ttgagcaaac cgttaacccc ttttaatgat agtatggttg aaaatagtgt
    14461 ctcaaaccat ttgacataag gacatggtgc tttcttgtta ctagaagacc ttcaatatta
    14521 tcaaaggtat ttaaaagtgt gataatcatt gagctatcaa gaccaaataa acgggtagtc
    14581 catatgtcac aataaaaaga agaaggagcc atgatcgtta agctaagcat atctgtttct
    14641 atagggtagc ctgtctgacg atctaagata tgatgatact gtttcccttt ggctgtaaac
    14701 tgcctttcat aaattccaga agtcacaaca gagtgattgt taaccttgat gacaccaaga
    14761 tgttgcccac gtttagcatc tggtttttga atgccaattc gaaaaatctt gtcagggctt
    14821 ttcggattag gtccatgaac gcgtacattt ccacctaaat taataagggc agagtcaata
    14881 ccatcttcaa tcaggtaggc cataatctta tcagtaatat aaccttttgc taaggctcct
    14941 aagtctaaag ccattcctac ttgttgtaaa aagacagtct gttttttgtc atctataaga
    15001 acctgtctag gatctgttag agctaactgt tgtgagataa ggttatgact aggcactcta
    15061 gcatcttcaa atccaattcg ccaggcttga acaagtggcc caatggcgat attaagatta
    15121 cttggtgttg acaagctatg agctttacca atttggacta ggttaaataa atcagagtgg
    15181 acgctgacgg gtttaacacc agccgcctga ttaatagcca tcaattcaga gtttgaatca
    15241 ttagctgaaa aacgattttt gtaagtatat aataagtcaa tgactctact tagttgttgg
    15301 caagctttgt cagattcgat ctgaatatca ataactgttc ccattagctt taattgttgc
    15361 gtaacaaaca taattagtcc tctttttagc agaatacccc cactaaggag tgggggaagg
    15421 tcattatgat ttttgtttca tttcaccttg aggatagtaa gttccttcag gcatatcgtt
    15481 gataaaaaca tggatatttt ctttaggtgc ttttgcaatg cgtgatacta cttcggtaac
    15541 ctcgcgagct aattgatttt tttgttcttg tgagcgtccc tcaaacaagt caattgttac
    15601 aaatggcata atgttactcc tttatattat tgggcatcat tgtaacataa tgctatgaaa
    15661 aagtacacac tgttttcaat ggctgggaaa acttcagcct ttgtggtaaa ataggtagaa
    15721 tactatagaa agtaggattt tccgctttgg ctcaactcta ttataaatat gggacaatga
    15781 attctggtaa aaccattgaa attttaaaag ttgctcataa ctatgaagaa caaggcaaac
    15841 ctgttgtcat tatgacaagt gctcttgata cacgtgatgg ttttggcatc gtctcaagcc
    15901 gtattggtat gcgacgagaa gctattccca tttcaaatga catggatatt ttcacattta
    15961 ttgcccaatt ggaagaaaaa ccttattgtg tcctgattga cgaaagtcaa tttttaagca
    16021 agcaaaatgt ttatgatttg gcgcgtgtgg tggatgagct aaatgttcct gtcatggctt
    16081 ttggtttgaa aaatgatttc caaaacaatc tttttgaagg ttcaaaacat ttgctattat
    16141 tggccgataa gattgatgaa atcaaaacaa tttgccaata ctgtagtaag aaagcaacca
    16201 tggttttaag gacagaaaac ggaaaacctg tctatgaagg tgatcagata caaattggtg
    16261 gtaatgaaac atatatccca gtttgtcgaa aacattattt taatccagag atttaaaagg
    16321 taatcggttt taaaggagat acaaagaaaa atgaatattt atgatcaatt gcaggcagtt
    16381 gaagatcgtt atgaagagtt aggtgagtta cttagtgatc cagatgttgt ttcagataca
    16441 aagcgattta tggaattatc acgtgaagaa gctaacactc gagaaactgt cacagcttat
    16501 agagaatata agcaagtcat tcaaaccatt tcagatgctg aagaaatgat caaagatgcc
    16561 agtggtgatc ctgaattaga agaaatggct aaagaagaac ttaaagaatc aaaagcagct
    16621 aaagaagagt atgaagaaaa attaaaaatc cttctattac ctaaagatct taacgatgat
    16681 aaaaacatta ttttagaaat tcgtggtgct gctggtggcg atgaagcagc gctttttgct
    16741 ggtgatcttt taacaatgta tcaaaaatat gctgaaactc aaggatggcg ttttgaagtt
    16801 atggaatcat ccgttaatgg tgttggtggt attaaagaag tggttgccat ggtttctggt
    16861 cagtcagttt attctaagct taaatatgaa tcaggagctc atcgtgttca acgtgtcccg
    16921 gtgacagaga gtcagggtcg tgttcatacg tcaactgcaa ctgttttggt aatgccagaa
    16981 gttgaagaag tagaatacga cattgatcct aaagaccttc gcgtcgatat ttaccacgcg
    17041 tctggtgctg gtggtcagaa tgtcaataaa gttgctactg cagttcgtat ggtacacatt
    17101 cctacaggaa tcaaagttga aatgcaagaa gaacgtactc agcaaaaaaa ccgtgataaa
    17161 gcgatgaaaa tcattcgtgc tcgtgttgct gaccattttg cgcaaattgc tcaagatgaa
    17221 caagatgctg aacgtaaatc aacagttggt actggtgatc gttcagaacg tattcgtact
    17281 tataatttcc cacaaaatcg tgtaacagat catcgtattg gtttgacact tcaaaaatta
    17341 gatactattt tatctggaaa aatggatgaa gttattgatg cactcgttat gtatgatcag
    17401 acaaagaaat tagaatctct caataactaa tgaactatgc tacattaatc agaacttatg
    17461 aagataaact agaacaaata gatgaggatc gcgaaaatct cgcctatgtt tttagcgaaa
    17521 tcaaagaatg gtcaagtcta gatatgttga ttcaccaaaa tcaagctgtg actcctgaag
    17581 atgctgttct tttggaacat attttctgtt ctctaagtca gcatttatct cctcaatata
    17641 ttacaggtaa tgcttatttt cgtgatttga agcttgcagt cgacaagcgt gtattaattc
    17701 caaggccaga aacagaagaa ttagttgaca tgattttagc tgaaaatctt gatgcaccgt
    17761 tgaatgtttt agatattggt acaggtagtg gagcgattgc tatttctctc aaaaaagaaa
    17821 ggcctaactg gcaagtaacg gcatctgata tttctagagc tgctcttgac ttggcaaaag
    17881 ccaatgctga tgcttaccag cttgatataa cgtttattga atcagatgtt tttagtctca
    17941 tttcaggaac ctttgatatt attgtgtcaa atcctcccta catatcctac gaggataagg
    18001 aagaagtcag tctaaatgtt ttgcaatcag agcctcattt ggcacttttt gctaaagaaa
    18061 atggctatgc tatttaccgt aagattattg aacaagctga caattactta actaaggagg
    18121 ggaagcttta ctttgaaatt ggttataagc aagctgaagg tataaaagat atgttacaag
    18181 cctattttcc tcaaagacat atacgagtcg taacggatat atttggcaaa gaaaggatgg
    18241 tggttgttga ttatggagta tctagctagt atcattgaat caggtgatgc ccttgttttg
    18301 ccaacagaaa cggtttatgg tctttttgcc aaggctttag atgagaaagc agtaaatgct
    18361 gtttatgact taaaacaaag accccgagat aaagcaatga accttaatgt ggctgatttt
    18421 aatagtatct tagccttttc aaaagaacag ccgagatacc tcaagaaatt ataccaagcc
    18481 tttttaccag gtccgttaac gattatttta aaagctaatg accaggttcc ttattggatt
    18541 aattcgggtc tttcaacggt tggttttcgc ttacccagtc atccaattac cgcagcttta
    18601 attcaaaaaa caggcccttt aattggtcct tctgcaaact tatctggcaa agctagtggt
    18661 cgagtttttg atcatattat gcaagatttt gactttcaag tgtttggtta tgcagatgat
    18721 ccttttctaa caggtaagga ttcaaccatc ttagacttat caggtgagcg tgctgtgatt
    18781 ttacgtcaag gtgctatcac caaagaagaa ttattagcca acgtgcctga acttcgcttt
    18841 taagagagga gccgcttgga atgttgagac cattaagtaa aacggactgt cctatgctac
    18901 aagaaattaa cgccaaagcc cttggctatt tagtttcgct tgacttgtta gaaaggcaat
    18961 atgaacgatt gattgaggat tgccatcact attttttagc ttatgccgac aaggatacca
    19021 atcaattatt aggctatgtt cacgctgaac ggtatgagac cctttatgct tctgatggtc
    19081 ttaatctctt gggcttggct gttttaccag cctatcagag aaggggaatt gggagtgcct
    19141 tactaagggc cctggaatcc caagctaggc aggaaggcat tgcctttatt cgcctcaatt
    19201 ctgccagtca tcgtaaagaa gcgcatgctt tttaccgaaa cctcgactat gcagatgata
    19261 aaacacaatt acgattcatc aaaaacttac aaggagatga caatgatttt tgataaaggt
    19321 aatgttgaag actttgataa agagctttgg gatgccattc atgctgaaga agaaagacaa
    19381 gaacatcata tcgaattgat tgcatctgaa aacatggttt caaaagctgt catggcagct
    19441 caaggttctg ttttaaccaa taagtatgca gaaggctatc caggtaatcg ctattatggt
    19501 ggaacagaat gtgtggatat tgtcgaaacg cttgctattg aacgtgctaa gaaacttttc
    19561 ggtgccgcat ttgccaatgt tcaagcccat tccggaagtc aagccaatgc agcagcttat
    19621 atggccttaa ttgaggctgg tgataccgta ttaggaatgg atttggctgc aggtggtcat
    19681 ctcacgcatg gctctccagt aaatttttct ggaaaaacct accattttgt gggttactca
    19741 gtagatgctg atactgaaat gttaaattat gaggcgattt tagaacaagc aaaggcggtc
    19801 cagccaaagc ttatcgttgc aggggcttcg gcctactcta gaagcattga ttttgaaaag
    19861 tttcgtgcca ttactgatca cgtaggtgct tacttaatgg tggacatggc tcacatcgct
    19921 ggccttgtag cagcaggtgt gcacccgagt cctgtccctt atgcgcatat tgtgacgtca
    19981 acaacccata aaaccttacg tggtcctcgt ggaggcttga tattaaccaa tgacgaagct
    20041 cttgctaaaa agattaattc ggccgttttc cctggtttac aaggaggacc tctggaacac
    20101 gtgattgctg ccaaagcggt tgccttcaaa gaagccttgg ttccagcctt caaagactat
    20161 gcacaagcta ttattgataa tactgcggct atggcagcag tttttgcaca agatgaccgt
    20221 tttcgtctga tctcaggtgg tacagataat catgtctttt tagtagatgt cactaaggtt
    20281 attgctaatg gtaaactagc gcaaaatctt ctggatgagg ttaatattac ccttaataaa
    20341 aatgccattc cttttgaaac cttgtcgcca tttaaaacct caggcattcg tattggttgt
    20401 gctgccataa ccagccgtgg tatgggtgtt aaagagagtc agaccattgc ccgtcttatc
    20461 atcaaagcct tggttaatca taatcagact gttattcttg aagaagtccg tcaggaagtg
    20521 cgtcagttaa ccgatgcttt cccactctat aaaaagtaag gaatcatgtt agatagttat
    20581 ataaaacgta ttgtcattca tcaattttct cccaatgaca ctgagttact gttatcagat
    20641 cgtttagtga gcattacacc gcgaattgat gaatatttcc ggaaaaaatt ggccaaagtg
    20701 ttctcggacg aagccaaacg tggtcagttt gaggctaata ataccttttt tacaaccatt
    20761 ggtgatgatt tgttggaaac gtctgttacc attgcccagt tatggaagga agcctttgtt
    20821 atttcagagg atcaaaaaac caatgattta gtctttgtcc agtttgataa ggatggcgaa
    20881 cccttttttg ctttcttgcg aattgctttg aaagaacagt ttgctcacct ttctgacaat
    20941 tatgaacatc catttacggt gacgcagaat aatctgccga gtcccaccca gacaccagat
    21001 gaagcactag tcattaatct caaatctggt cagtactact tgattgaaaa gcgtgtgaag
    21061 cataatggca gttttgctaa ttatttttca gaacacctct tgaaagttac acctgagcaa
    21121 tctgttaaaa agtctatcaa aatgatagaa caaaccgctc aaaaaattgc agagcatttt
    21181 aatcaagatg attttacttt tcagtcaaag atgaaatcca ctctttttaa gcagttagaa
    21241 gcagacgacg ttttatcacc agaaaaatta gctgaccaac tctttgatga taatttaaca
    21301 gcccgtttaa cctttgtggg tcaagtcaaa gaagtcattc cagaacctat aaaaattagc
    21361 gatattgatc attctagaca gataaaaaaa ctagaaaatc aaaagctatc gttatcaaac
    21421 gggatagaat taacagtacc aaatgccatt tatcaggatg ctgaagcggt tgaatttttg
    21481 ttaaatgatg atgggactta ttcaatcttg attaaaaata tagaggatat taaaaccaaa
    21541 tagatgttta gacttttaaa gcgtgcctgc agttttcttc ttctttttgt catttatcaa
    21601 tcctttgtta ttcatcacaa tgttcaacgt gttttggcat ataagcctat ggttgagaaa
    21661 acattagcag aaaatgatac aaaggcaaat gtagacttag tcttagctat gatatacacc
    21721 gagacaaaag gaggagaagc agatgtcatg caatccagtg aaagcagttc aggacaaaaa
    21781 aactcgatta cagatagtca ggccagtatt aagcacgggg tgaatttact gtctcataat
    21841 cttgctctag ctgaggaagc aggagtagat tcttggacgg ctgttcaggc ctataatttt
    21901 ggaacagctt atattgatta tattgctaaa catggaggtc aaaataccgt tgatttagcg
    21961 actacctatt ccaaaacagt tgtggcgcca agcctaggca acactagtgg tcaaacctat
    22021 ttttattacc accccctcgc cttgatttct ggaggtaagc tttataagaa tggcggcaat
    22081 atctattact cacgagaagt tcatttcaat ctttatttaa ttgaactgat gagccttttt
    22141 tagaaagtta tcatgaaacg attacgtcca tatttgaaag ggtacctaaa agaaagtatc
    22201 ttaggtcctc tttttaaatt attagaagct ttatttgaat tattagtccc tttgttaatt
    22261 gctaacatga ttgatatatc gattagtcaa cacaacagcc agggaatttt gagggttgtt
    22321 ttaacattat ttggtttagc aaccattggc ttattgattt ccgttacagc ccagtatttt
    22381 tcttcgaaag cagctgttgg ttttacaaga caaatgacag atgatttgtt taaaaaaatc
    22441 atgtttttga gcaaggagga ccaagaccat attggttatg ctagtctgtt atcacgattg
    22501 accagtgata gttttcaaat tcaaactggt atcaatcaat ttttgcgtct ttttctaagg
    22561 gcccctatta tcgtatgtgg tgctatggta atggcttatt ggattagtcc aagtctaacc
    22621 ctatggtttg tgatgatggt gattgtctta ctaacacttg tttttgttat gtcacattta
    22681 ttagatcccc tttatctctt aatccgccga gaaacagatc acttggttcg tttgactagc
    22741 caacagttac aaggaatccg agtaattaag gcttttaatc aaacccaaaa agaactccaa
    22801 gcatttaagg agcaaaatat gctcttaagt cgccaccaat atcaagctgc taccctagcc
    22861 aatgtcttga atcctatgac ttttttagtg gtcaatctta ctctgttaat cttgatttgg
    22921 caaggaagtt ggcaagtagc tcatagatcg cttagtcagg gcatgttggt tgctttaatt
    22981 aattacctct tgcagatttt ggcagaactt ttgaaaatga ccatgttgat gggaaccatc
    23041 aatcaaagtg taacagccgc aaaacggatt aatcaggtgt ttgttttagc tgatgaagcg
    23101 cctttgccct tacttaaaga tggtcctatt tcaactcatc tgttgaccat ccggcacttg
    23161 acctttactt atccaggagc agcagagcca agtctgtatg atattcagtt aagtgctgat
    23221 cagggagaat ggattggcat cattggtggt actggagcag gcaaaacgac tttgattgac
    23281 ttgatctgcc aaacttattc acaatatagt ggtgagatta gtcttaattg gcaaggagaa
    23341 gtgccaaaaa cactaaccga gtggcgaaat gtgattgctc ttgttcctca aaaagctcaa
    23401 ttatttaaag gaacgattag aagtaacctc ctactgggac aatcaatgcc tattaatgat
    23461 gaggagctgt ggcgggctct tgaattggct caagcaaaag agtttgtcgc tgccttacca
    23521 gaacaattag aggcacctgt tgaagccttc ggccgtcatt tttcaggagg gcaacggcaa
    23581 cgtctagcca ttgccagagc acttctgaag ccaaaaccca ttttgatttt ggatgatgcc
    23641 agttccgcct tagacaatga gactcgagga cgacttttta aagttctaaa agaagagtta
    23701 tcagatgttt tagtgattct agtcacgcaa tccattaaga atttgcagtt tgctgataag
    23761 attttagtgt tggaacaggg ccatcaattg gattttgcca gtcatgacca gttaaaagta
    23821 agcaatgcac tttatcaaga aatgctagcg ctttacgtga agggggagca aaaatgatta
    23881 aaacagatca tcacctccta aagcgagtgc ttcaggattt gttaaaaaaa cctctacctg
    23941 tttgtattct cgtgatcgct agttttgtac aagttggttt aagtgtttac ttgcctgttc
    24001 ttatcggtaa agccgttgat atgagtttgt cagtcaattc ttggcaaact ttaaaatggc
    24061 tgttggggca aatgttagtt attattgtgg tcaacacatt gattcaatgg gtgatgcctc
    24121 ttgtctatag tcgtttgcta tatcaatata gccagcaatt gaaagataag cttttggaaa
    24181 aaattcatcg tcttcctttt gcatatctag atcgtcaaac cattggagat ttggttagtc
    24241 gagtgataac cgacactgag caactgatca atggtctaca aatggttttt aaccagttta
    24301 tacttggact attgacgatt ctgtgtacca ttatagctat ggcacagatt gactggctca
    24361 tgttaatctt ggttttggtg ttaacaccaa gctccctctt tttagctcgt tttattgctc
    24421 aaaagagttt tcattatgca caagcacaga ccaaaagcag aggaaattta gctcagttta
    24481 ctgaagaaat ccttcgtcaa gaaggtttgg ttcaactgtt taatgctcaa gagcagtcta
    24541 tctgtgatta tcatgtttta aataaaacct attgcgaggc ttcacaaaaa gccatttttt
    24601 acgcctcaac agtcaatcca gccactcgct ttattaatag tgtcatttat gctttactgg
    24661 caggtttagg ggctgttcgt atcatggctg gacttttttc agtaggtcag ctaaccactt
    24721 ttttaaatgt tgttgtccaa tataccaaac ctttcaacga tatttcatct gtcttggcag
    24781 agatacagag ttctttagct tgtgcgcaaa ggctttatga ccttttagat attgaaataa
    24841 aagagcaaga gcactttcta acatttaagg catcagcggt taaggggcaa attgactttg
    24901 aagaagtaag tttttcttat caaaaagaca ggcccttact gaaagatatt aatttttctg
    24961 ttcctgcggg ttccaaggta gcgattgtag ggcctacagg tgcaggcaaa tcgactttaa
    25021 tcaatttact catgcgcttt tatgaacttg atgttggtag catcaagtta gataaagttc
    25081 ctattaagtg ttatgctaag gaagaactta ggtccattac tggcatggta ttgcaagaaa
    25141 cctggttgaa agatgcgact gttcatgagt tgattgctta cggcagtgaa gaggctagcc
    25201 gtgatgaagt agtggcagca gccaaagcag ctcatgcaca cttctttatt atgcaacttc
    25261 ctaagactta tgatacttac ttaagtgctt ctgatgatgc tttgtcccaa gggcagctcc
    25321 agttattagc tattgccaga atgtttttga aaaaaccaaa agtcttgatc ctagatgaag
    25381 ccacctcctc tattgatatt agaacagaag ctgttattca agaggcacta aaagaactca
    25441 tgagaggaag gaccagcttt atcattgccc atcgtttatc aacgattcaa tcagctgatt
    25501 tgattcttgt tatggatcaa ggtcgattgg ttgagtgggg aacacatgcc agcttaatgt
    25561 caaaaaacgg atgttatgct agattacaaa agatagaata aagttcgtct tttaacaaag
    25621 gtgaactttt taactcttcc taaagttagt taattaacaa actttaaact gttatataaa
    25681 aaaataacag cgaaaaagcg gacgatcttt ttttataagt gagaaaaaac agttgactaa
    25741 agaagaaata actcaaaaaa gtgagcaata tatttggaag cgttttttga ctgtggtata
    25801 atagagccct atataatatt gtgaaatgag gaacaaaata tatgagtaaa atcgttgttg
    25861 ttggtgcaaa ccatgctggt acggcctgta tcaagactat gttaacaaac tacggtgatg
    25921 ctaatgagat tgttgtattt gaccaaaact caaatatttc atttttaggc tgtggtatgg
    25981 cactttggat tggtgagcaa attgctggac cagaaggact tttctattca gataaagaag
    26041 aattagagtc tttaggggct aaagtttaca tggaatcacc tgttcaatca atcgactacg
    26101 atgccaaaac agtgacagcg cttgttgatg gtaaaaacca cgtggaaact tacgacaagt
    26161 tgatttttgc aactggctca caacctatct taccaccgat taaaggtgcc gaaatcaaag
    26221 aaggatcact tgaatttgaa gcaactcttg aaaatcttca atttgtgaag ttataccaaa
    26281 actcagctga tgtgattgca aagcttgaaa acaaagacat taaacgtgta gccgtagttg
    26341 gtgctggtta cattggtgtt gagttagctg aagctttcca acgtaaaggt aaagaagtgg
    26401 ttctgattga tgtcgtggac acttgcttgg caggttatta cgaccgtgat ttgactgact
    26461 taatggctaa aaacatggaa gaacatggta ttcaactagc ctttggtgaa acagttaaag
    26521 aagtagctgg taatggtaag gttgaaaaga tcattactga caaaaatgag tacgatgtgg
    26581 atatggttat cctcgccgtt ggtttccgtc caaacacaac tcttggaaat ggtaagattg
    26641 agcttttccg taatggtgct ttccttgtca ataaacgcca agaaacttct attccaggtg
    26701 tttatgctat cggtgactgt gcaactatct acgataatgc tactcgcgat acaaactaca
    26761 ttgctttagc ttcaaatgcc gtccgtacag gaattgtagc agcacataac gcttgtggta
    26821 cagaccttga aggaattggt gtccaaggct caaacggtat ttccatttac ggcttgcaca
    26881 tggtatcaac tggtttgact cttgaaaaag ctaaacgact tggttttgat gctgcagtga
    26941 ctgagtatac tgataaccaa aaacctgaat ttatcgaaca cggtaacttc ccagtaacca
    27001 ttaagattgt ttacgataaa gactcacgtc gtatcttggg tgctcaaatg gcagcgcgtg
    27061 aagatatgtc aatgggaatt cacatgttct cacttgctat ccaagaaggc gtaaccattg
    27121 aaaaattagc tttgacagat attttcttct taccacattt caacaaacct tacaactaca
    27181 tcacaatggc agcacttggt gccaaagact agtatctgat aggaaaaagc cagagcagtt
    27241 cagcagcact ggcttttttg ctttttaatt gttgcaacct gaaaagttct aaacttatgt
    27301 ttatcctctt atagcacgtt ggaaaaggaa tatcaggcaa aacaaaaaga gactgaagtc
    27361 tcttttgtga ttagtttttg gcagcagaag caaattcttc cttagcgaaa gcttcatcga
    27421 tgatagcttt taattgattt gcagaggctt gcattttttg caattcagca tcgttaagtg
    27481 gaatgtttac tggacgaaca attccatacg ctccaacgat agctggttga ccaatatagc
    27541 aatcttcaac accttcgtat tggccttctt ggaaaacaga aagcggaaga acagcatttt
    27601 catcatcaag aatagctttt gtaatacgag ctagggcaac tgcaataccg tagaaagtag
    27661 cacctttttt atcgatgatt gagtaagcag catcacgtac agaaatgaaa agatcaacta
    27721 ggccttgctc atcaatgtca cgattagctt ggagccagtc gtaaagacct acaccagcaa
    27781 cgttagcgtg tgaccaaaca gcaaattcag agtcaccgtg ttctcccatg atgtaagcgt
    27841 gaaccgaacg cgcatcaaca ccgattttag cagccagagc ttgacggaaa cgggctgaat
    27901 ctagagatgt acctgaacca atgacacgct ctttagggaa acctgagaat ttccatgttg
    27961 agtaagtcaa aacgtcaact gggttagcag caacaagaaa gattcctttg aaaccagatg
    28021 caacgatttg tgtaacaacc tctttattga tacgaaggtt tttttcaaca aggtcaaggc
    28081 gtgtttcacc tggtttttga ggagcaccag ctgttaagac aacaagatca gcatcatgac
    28141 agtctgagta gtcagctgca tagatttttt taggtgatgt aaaagctaga gcgtggctta
    28201 aatcttctgc atctccttga gttttttctt taaaaatatc aataatacca agttcttgag
    28261 caatattttg tgttaccaat gcaaaagcgt atgatgaacc gacggcacca tcaccgacca
    28321 agattacttt tttgtgttgt ttagttgcag tcatttctaa acatctcctt aattttatta
    28381 gagcaaaagc tcatacggtc ttattttaac atattgataa ttgtttgtca ttgaattcag
    28441 aaaaataatg aaaatagttt cctgataacg cttccaataa gaaaaaataa ggaatttatg
    28501 gtataatgaa atctagtatt gactagaaaa ggagcattcc ttaaatgcaa gatcgaaatt
    28561 taattgacgt caatctgaca agtgaaatga aaacgagttt cattgactat gccatgagtg
    28621 tcattgtggc aagagctttg ccagatgtgc gtgatggtct gaaacctgtg catcgtcgta
    28681 ttctctatgg gatgaatgaa ctcggtgtga cacctgataa accgcataaa aaatctgctc
    28741 gtattacggg tgatgtcatg ggtaaatatc acccgcatgg ggattcttct atttatgaag
    28801 ctatggttcg tatggctcag tggtggagtt atcgccatat gcttgttgat gggcatggca
    28861 attttggttc tatggatggt gatggtgctg ccgctcaacg ttatactgaa gcgcgcatga
    28921 gtaaaattgc gcttgaatta ttaagggata tcaataaaaa taccgttaat tttcaagata
    28981 actacgatgg aagcgaaaga gaaccagtag tattaccagc tcgctttcct aatttattag
    29041 tcaatggagc gacagggatt gccgttggga tggcaactaa cattccgcct cataatttgg
    29101 cagagtctat tgatgctgtc aagatggtaa tggaacatcc agactgtaca acaagagagt
    29161 tgatggaagt gatccctgga cctgactttc cgactggtgc ccttgttatg gggcgctcag
    29221 gtattcatag ggcttatgat actggtaaag gttctatcgt tttacgctct cgaacagaaa
    29281 ttgaaacaac tcaaacaggt cgggaacgta ttgtggttac tgaatttccc tatggcgtca
    29341 ataaaacgaa agtgcatgaa cacattgttc gtttagcaca agaaaaaaga ctagaaggta
    29401 ttacagcagt tcgtgacgaa tctagccgtg aaggagtgcg ttttgttatc gagattcgtc
    29461 gagaggcatc cgcgacagtt atcttaaata acctctttaa attaacaagc cttcagacga
    29521 atttcagttt taatatgttg gctattgaaa atggtgtgcc taaaatattg tcactcagac
    29581 aaatcattga taattacatt agtcatcaaa aagaagttat tatacgtcgc acccgatttg
    29641 ataaagataa agctgaagcc agagctcata ttttagaagg cttactgatt gcccttgatc
    29701 atttagacga agtgattgct attattcgta acagcgagac agatgtcatt gctcagacag
    29761 aattgatgtc acgtttcgac ttgtctgaac gccaaagcca agctattttg gatatgcgtt
    29821 tgcgtcgttt gactggtttg gaacgtgata agattcaatc agaatatgat gatttgttgg
    29881 ccttgattgc tgacttatct gatattttag ccaaaccaga acgtattatc actatcatca
    29941 aagaagaaat ggatgagatc aagcgtaaat acgctaaccc acgccgtaca gaattaatgg
    30001 tcggtgaagt cctttctcta gaagatgaag acctaattga agaagaagat gttttgatta
    30061 ccttgtcaaa taaaggttat atcaagcgtc ttgctcaaga tgaatttcgt gcccagaagc
    30121 gtggtggacg tggcgtccaa ggaactgggg tcaacaatga cgactttgtc cgtgaattga
    30181 tatcaacaag tacccatgat actttgctct tctttacgaa ttttgggcgt gtctatcggt
    30241 tgaaagctta cgaaattcca gaatatggtc gtacagcaaa aggtcttcca attgttaatc
    30301 tattgaaatt agaagatggt gaaaccattc aaactattat caacgcacgt aaggaagaaa
    30361 cagcaggtaa atccttcttc tttacaacga aacaaggcat tgtcaaacgt acagaagttt
    30421 cagaatttaa taatatccgt caaaacggtc tccgtgctct taagttgaaa gagggagatc
    30481 agctgattaa cgtccttttg acaagcggtc aggatgacat tatcattgga actcattccg
    30541 gatattctgt tcgttttaat gaagcaagca tccgcaacat gggccgatca gctacgggtg
    30601 ttcgcggggt taagcttcgt gaagatgatc gcgttgttgg cgcgtcacgt attcaagata
    30661 accaagaagt tcttgtaatt accgaaaatg gctttggtaa gagaacaagt gctacagact
    30721 atcctacaaa aggtaggggg ggaaaaggaa taaaaacagc taatattacc cctaaaaatg
    30781 gtcaattagc tggattggtt accgtagatg gtacagaaga tatcatggtg attacaaata
    30841 aaggtgtcat tattcgcaca aatgttgcaa atatttcgca aacaggtcgt gctactttgg
    30901 gtgttaaaat tatgaaacta gatgctgatg ctaagattgt aacatttacc ttggttcagc
    30961 ctgaagacag tagtatcgat gaaatcaata ctgatcgtga aaatagtatt tcaaaaaata
    31021 aagataatta atcataacaa ggagtaaaaa atggtaaaaa aacaaaagcg tcgaaaaata
    31081 aaatccatgt cttgggcaag aaaactacta atagctgtac ttttaattct aggtttagca
    31141 ttgcttttta acaaacctat ccgaaataca ttaattgctc gaaactctaa taaatatcaa
    31201 gtaacgaaag tttcgaaaaa acaaatcaaa aagaataaag aggctaagtc aacatttgat
    31261 ttccaagccg tagagccagt tagtacagag agtgtcttgc aagcacaaat ggcggctcag
    31321 caacttcctg ttataggggg cattgccata ccagagcttg gcattaattt accaattttt
    31381 aaaggtttag gaaatactga gcttatttat ggcgcaggaa cgatgaaaga agaacaagtt
    31441 atgggaggag aaaataatta ttctcttgcc agtcatcata tttttggaat tacaggttca
    31501 tctcaaatgc tcttttcgcc gcttgaaaga gcacaaaatg ggatgtccat ctatttaaca
    31561 gataaagaaa aaatttacga atacatcata aaagatgttt tcacggtagc tcctgaacgc
    31621 gttgatgtta tcgatgatac agctggtctc aaagaagtga ctttagtgac ttgtacagat
    31681 atcgaagcaa cagaacgtat tattgtcaaa ggagaactaa aaacagaata cgattttgat
    31741 aaagcgcccg ccgatgtatt gaaagctttt aatcattctt ataaccaagt atctacctag
    31801 atatatctta aatataatat ttaaaaagta ggaccataga gaaaatttat ctcatcctac
    31861 tttttttgaa aggagaaata tgatgaaact aaatgccatt caccacgttg ctattattgt
    31921 atctgattat catctgtcaa aagattttta tgtgaataaa ctcggatttg aaattatcag
    31981 agaaaattat cgtcctgaca agcatgatta caaattagat ttatcttgtg gtcgtattga
    32041 attggagatt tttggtaagg tgacaagtga cccctactat caagctcctc ctaaacgtgt
    32101 aagtcaacca gaatttaaaa gtgaggcctg tggtttgagg caccttgctt ttcgtgttac
    32161 caacattgag agttatgtag atgatctaaa gagcttagga attccagtgg agcctattag
    32221 gcatgatgat tacacaggtg agaagatgac tttctttttt gatccggatg gtttgccttt
    32281 agaattacat gaatagactt attaggttaa cgattggatc gtgctattaa actcgttaaa
    32341 aatagttatt tgttgtatct tcttttgctt gattaatctc ttttgatcgt taaatgattt
    32401 ggttaacttt caaagtgaag agcaattttt ggagtaatct tgtcgaagtt ttttaataga
    32461 ataactatag gaaaagcaaa atatttgacg ataaactctt acagtgttat aatgacaata
    32521 taagtaaata actgtgttgt cactttgttg aaatgttttc gtattaatgt ttttttatct
    32581 attacgatag ataattttac ttcaattttt gattgaaaat actaaaataa gtgatgtggt
    32641 cactttgaca accatttatt ggtcctttta gataagacaa ttttgtggct cttcagttga
    32701 aaggatgtgt tgttgatgtt agaggaaaca atcatgttaa attaactcag gcttaaagac
    32761 caaaaaagga gtgaagtcta ttatgaaaaa aagaaatttt aaacttacag aaatgttaca
    32821 attggtttta ttagtggttc ctgctgtaaa acttgctaaa aaaatgttta acgatagtaa
    32881 aacaccgtct aaaagaaagt aggtctacaa tgactaaaaa aaatcatggc gttttttggg
    32941 ggttgttgct tggatcagca gcagctagca ttgcttactt aagtttatcg tcttccaaaa
    33001 aagatcaact cttgaaaaat agtgctaaaa aaatagatga tctcaacgct tacttgcaag
    33061 ataaaagtaa gcaagttctg gatgcagtat cggaaaaagt acaagaatcc aaagatgctg
    33121 ttgaagttta tggtggtatt gccgcagaaa ccgttgaaga aaagtggcaa gataccaaag
    33181 atgctgttga agtttacggt ggtattgccg cagaaacagt tgaagaatct ttgggacagg
    33241 ctaaagaaaa ggtagaagga attggcgaag ctactagtca aactatccaa tctaaaatgg
    33301 aaaaactcac cagcgataag acagatgctg atgatgatga aaaataggtt ttaaaatacc
    33361 tttaagataa gacaaaaagt gccattaggc acttttttaa tcttctgttg gaacaataat
    33421 cgaaatggct tttggaatga tatctaattg aatgggcaga tagtcacttt tatccccatc
    33481 aatcctggta cgtggtaata tcgcttgttt tttagcttgt ggtagtaagc taagcgtatt
    33541 ggcttgaaaa tgactgattt cctctgcttt ggaaaaatca ccctgtttaa aatcattaat
    33601 atgccataaa aatttaaaga aagagacttt tttcatggta taaacttgga aatagccatc
    33661 gtcagcttga gcaccaggag aaaaagaagg aaaaccagca atggtatttg tcatcgtgat
    33721 taagagaaac ttcgttttta ggtgaatacg atggttgtgg ctaattaaag agatggcata
    33781 gctgcgattt cgtttcagta ttcgaatact atcttttaaa aatgctagag gaccaaagcg
    33841 tcgtttttcc tcagccgtta cgtcggcagc aatatcagct agtaatccta aggttaaact
    33901 ggaaatcatg tattgctggt tagctttgca aatatcaact tgcttgattt gtccagtcaa
    33961 gatagtatcc aacgcctcag taatttgtaa agggatatgc atagccttgg caaaattatt
    34021 gactgtccct gagggcacta agcctattaa acaatgagct cctccttcat agatgccacc
    34081 gatgatttta tttagtgtcc catcgccacc aagagggata accaagtcaa tcttgtcctt
    34141 agcagcttgt tttgctaatt gaaaagcctg gtcagcacct ttaggggtaa taacttctac
    34201 agaatcttcg gaaaaaccat gttggcaaaa atagtctttg acttgcccag caagttggtc
    34261 ttctttcttt ccagaattag gattgtaaaa aatccgaacg gttttcatca ggtctctcct
    34321 ttgacagctt attacttgct atccattata ccacttctaa gaattgatgt cttacaccaa
    34381 ctcatcacat taagcctctc aatcagtctg agcatctatt tatcttaaag cataaagaaa
    34441 gtgatagcga taaattggag ggcagaggcc aataaaataa agagatgcca aatcatgtgg
    34501 aagtagggtc tttttttggc ataaaatacc gctccaatgg tataagacaa gccaccaaat
    34561 aacatgagaa gaccaaaagc aagactagtt ttttgaatga tgactggcaa gataaacaca
    34621 acgagccagc ccataacgat ataaagcatc aaactgaatt tttcattgat acgtttggca
    34681 aaaattttgt ataaaatccc aaaaagcgta atgccccact gcaaaacaat aatgatatag
    34741 cctagccaac cagaaacaag ggataaggca acaggtgtat aacttcctgc gatagcaatg
    34801 taaatcatac tgtgatcaat aatgcgtaga atgtatttgt gaaccgaacc ataagccatg
    34861 gagtggtaaa tcgtagagga caaaaacatc aaaaagagac tgatgacaaa gatggagata
    34921 ccaatagcgg ctttaaggtc ataagtttga taagcatagc tggctgaaat aggaagtaga
    34981 atgagcatag caaatgctcc gatagcgtgt gtcacgctgt ttgctacttc ctcactaaaa
    35041 gataagggta aactttgttt aaaggtttgg ttcattgggt cacctcctgt gataaataaa
    35101 tagttttgtg gtaatctttg accgtttgac aggcaacctg cacaatcggt ggaatgtcct
    35161 cctcaatggg agctttctga ttccaacagg ttacaaaagt attgtagaga ctttcagaac
    35221 cagcctgtgc ctgaagttcc tccaatacgc gactaatatc ttgaatagga aataccgttt
    35281 taaacaaact gatggcaatt aagcgcgcta gttgttgctt ttggtatttt ttcttgatag
    35341 gtttagtcac atacccatgc ttgacgtaat tattaatcat agatgccgtt agtgatttat
    35401 tatctgacac ttctgaaaaa tcagtgcact ggttgacata aagtaacact tgatccaaat
    35461 ataagtctaa atcagggagg tccttccaat aaggtaatga tggaaaaatc atagtttcgt
    35521 ctctctatct agttttgata actagattat attattaatg aaaacttatt gcaagcaaaa
    35581 actgtaaaga cttaaaagag gaaagtagaa atggcgaagt gaagctaatc atgctataat
    35641 gttaaagaat tgattgggat agatgccttc tgtcgcaatc agactatttt atcacgaaga
    35701 agatgatgct acgaaaggaa tgatacactc atggcaatga ttcaatggtt tcctgggcac
    35761 atgtccaaag ccagaagaca ggttcaggaa aatgtaaagc atgttgactt tgtaactatt
    35821 ttagtggatg cacgcttacc actttctagt caaaatccca tgcttacaaa aattgttggt
    35881 gataaaccta aattaatgat tttaaataaa gctgacttgg cagatgcaac tcgaactaaa
    35941 gagtggaagg cttattatga aagtcaaggt attaaaacat tagccatcaa ttccaaagaa
    36001 caatcaacgg ttaaaaaagt aacagaagca gccaaggaac tcatggctga taaaattcaa
    36061 cgcttgcgag agcggggcat tcaaaaagaa accttgcgaa ccatgattat tggcattcca
    36121 aatgctggta aatctacctt aatgaatcgc ttggctggta agaaaattgc tgtagttggc
    36181 aataaacctg gtgtgactaa aggacaacaa tggttgaagt ccaataagga attggaaatt
    36241 ctagacactc ctggtatttt atggccaaaa tttgaggacg aattggtggg cttaaaatta
    36301 gctttaacag gtgctatcaa ggaccaatta ctaccaatgg atgaagtgac tatctttggc
    36361 ttgaattact ttagggaata ctaccctaat cgtttaacca aacgttttaa gaatattcct
    36421 cttgaggaag aagctcctga aatcattatg accttgacac gccaacttgg atttaaagac
    36481 gattatgacc gtttttacac tttattcgtt aaggaagttc gtgatggtaa attaggtcaa
    36541 tacaccttag atcaggtggg aaatatggat gccgactagt attaaagcta ttaaagaaag
    36601 cttagaggcc gttactagcc tcttggaccc cctctttcaa gaattggcaa ccgacactag
    36661 gtcaggcgtc caaaaagctc taaaaagccg acaaaaggct attcaggccg agttagcaga
    36721 agaagaacga ttagaagcca tgctttctta tgaaaaagct ctttataaaa aaggttatca
    36781 agccattgca ggtattgatg aggtgggacg tggtccctta gcaggtcccg ttgtggcagc
    36841 ttgtgtgatt ttacctaagt attgtaaaat taaaggcctt aatgattcta aaaaaatccc
    36901 taaagctaag catgagacca tttatcaggc agtgaaagaa aaggctttgg ctatcggtat
    36961 cggtattatt gacaatcagc tgattgatga ggtcaatatt tatgaagcaa ccaaactagc
    37021 tatgctagaa gccattaaac agttggaggg ccaactcaca caaccagatt atctcttgat
    37081 tgatgccatg acattggata ttgctatttc gcagcagtct attcttaaag gcgatgccaa
    37141 ttccttgtct attgcagcag catcaattgt agctaaggtc accagagatc agatgatggc
    37201 taactatgat cgcatttttc ctggttatgg cttcgctaaa aatgcaggct atggcaccaa
    37261 agaacattta cagggattaa aagcttacgg cataacgcct atccatcgta aaagttttga
    37321 acctgttaaa tccatgtgct gcgattcaac taatccttaa aaagttctgt ttttagcaga
    37381 atttttttct tttttacgaa taaatgaagt aaggaggtaa cttagtgaat cattttgaac
    37441 tttataagct aaagaaagct ggactgacta ataaaaacat tctcaatatt cttgactacc
    37501 aaaaacaaca ggaaaaatcg ttgtcacttc gagatatggc cgttgtttct ggctgtaagc
    37561 atccgtctca ctttatagaa gcctataagc agttagatat tcaaaaatta aaaatagaat
    37621 ttaaacaatt tcctagtatt tctatcttag ataagcatta cccaatggca ttgaaagaaa
    37681 tatacaatcc acctgtcctc ttgttttttc agggaaattt agaccttctt gagaaaccta
    37741 aattagccat tgtcggctcc agacgctcaa gcgataccgg agtaaagtct gtccgtaaaa
    37801 ttcttaaaga actcgggaac cgttttgtga ttgttagcgg acttgctcga ggtatcgaca
    37861 ctagtgctca tttagcctgc cttaaaaatg ggggacaaac catcgctatt attggaacag
    37921 ggttggatcg cttttaccct aaagaaaata gggagttgca aactttctta gggaaaaatc
    37981 atcttgtgat aacagaatac ggtccaggag aagaagcttt atcttatcac tttccagaac
    38041 ggaatcgtat tatcgcaggc cttagccgag gtattcttgt cgttgaagca aaaaatcgtt
    38101 caggttcctt gattacttgt caaattggga tagaagaagg ccgagacatt tttgctgtcc
    38161 caggaaacat tttggacggg aaatccgaag gttgccttca gttaattaaa gagggagcaa
    38221 catgcgtcac atcgggcatg gatatccttt cagagtacta aaaaagttaa agtttcttcc
    38281 tatatagcat ttttttattg acagtttctt aaaaatggga tattatgcta taagctttaa
    38341 acaaactgtt ataggaagtg tgtcgaattg ggaacaaaaa ctacaactaa gccaaaaacg
    38401 ggtactaaaa agtccaccac taaaaagaaa tcaacagcga aaaaaaatct cgttattgtt
    38461 gaatcacctg ccaaagctaa gactattgaa aaatatcttg gacgcagtta taaagttgtt
    38521 gcttcggtag gacatattcg tgacttaaaa aaatcgtcta tgtctattga ttttgataat
    38581 aattatgagc cacaatacat taatatccgt ggtaagggac cccttatcaa ttctttaaaa
    38641 aaagaagcca aagctgctaa aaaagtttat ttagctagtg acccggatcg tgagggagag
    38701 gctatttctt ggcatttgtc acatatctta ggacttgatc ctcaagataa taaccgagtg
    38761 gtttttaatg aaattacgaa agatgcagtt aaacacgcct ttgtggagcc tcgtcagatt
    38821 gatatggact tggtagattc tcaacaagca cgtcgtgttt tggaccgtat tgtgggatat
    38881 tccatttcac caattctttg gaaaaaggtc aaaaaaggac tttcagcagg acgtgtccag
    38941 tcggttgctt taaaactcat cattgaccgt gaaaatgaca tcaaagcatt tgttccaaag
    39001 gaatactggt ctattgatgg tctttttaaa aaaggaacta aaaagtttca agcgactttt
    39061 tacggtatta atggcaaaaa aacaaagctt gataataaca acgatgtcaa agaggtatta
    39121 gcaaagctaa caaatgaaga ttttcttgtc agcaaggttg acaagaaaga gcgacgtcgt
    39181 aatgctccct taccttacac aacatcatct cttcaacaag atgctgctaa taaaatcaat
    39241 ttcagaacgc gtaaaaccat gatggtagcc caacaactgt atgaggggat tcatttagga
    39301 gaaaatggaa ctcaaggttt aattacctat atgcgtacgg attctactcg tatcagtcca
    39361 gtagcacaaa acgatgctgc tcaatttatt atcaatcgct ttggagctaa ttattcaaaa
    39421 catggtaatc gtgtcaaaaa taccagtggt gcccaagatg ctcacgaggc gattcgtcca
    39481 tctagtgtta atcatacgcc agactctatt gccaaatacc ttaacaagga tcagttaaaa
    39541 ctttatacgc ttatttggaa tcgttttgtg gctagccaaa tgacagcagc tgtttttgat
    39601 accgtaaagg tgaacttgga gcaaaatggc gtgatttttg ttgccaatgg tagccaaatg
    39661 aagtttgatg gttacatggc tgtttacaat gattccgata aaaacaaaat gttacctgag
    39721 atggcagaag gagaaacggt taaaaaaata tcgacctctc cagaacagca ctttacgcag
    39781 ccaccagctc gttattctga agcaactctg attaaaacgc tagaagaaaa tggtgttgga
    39841 cgtccatcaa cttacgctcc aaccttagaa gtcattcaac gcagatacta tgttaaattg
    39901 tctgctaagc gctttgagcc aactgagctt ggggaaattg tcaacaagct tattgtcgaa
    39961 tttttcccag atattgttga tgttgccttt actgccgaga tggaaggtaa gctagatcaa
    40021 gttgaaatcg gagaagaaca atggcaacat gttatcgatc aattctatca accctttgtc
    40081 aaagaattga ataaggctga gtctgaaatt gaaaagattc aaatcaaaga tgaaccagct
    40141 ggcttcgact gtgatgtttg tggtcaccca atggtcatta agttaggacg ttttgggaaa
    40201 ttttacgcgt gtagcaactt cccagagtgc cgtaatacaa aagccatcac taaagaaatt
    40261 ggtgttactt gtccggtttg tcataaagga caagttatcg agcgtaaaac caaaaaaaat
    40321 aggatatttt atggttgtga tcagtatcca gattgtgagt ttatctcgtg ggatttacct
    40381 attggacgtg cttgccctaa gtcaggtgac tatcttattg agaaaaaagt tcgtggtggc
    40441 aaacaagtaa tgtgtagcaa tgagacctgt gattacaagg aagaaaaaat taaataaaaa
    40501 aagaattgga actccttgtc ttgttccaat tcttttttta tttacaaagg tatttttaac
    40561 tacaaaaatc gctagttcgt ttttaaaagg cttaaaaatt cctcaataac tggactgaaa
    40621 ctcgcatcat ctcggtaagc aatcccaata gggtaaaaat tatttttatc ttgcaaagga
    40681 atccaaacta agttatctac ctgattaaga ctcttaaaat cactcgggag gatagtcaag
    40741 gtatttaaat cttgcaaact atgaataaga acttcccaat cattgtgttt aaagacaata
    40801 tctggttcaa aaccgagagc tcggcatttt ctaggaagca tttcgcctag catgtagtga
    40861 tcgtttaaag aagcaatctt atagcctttt aaatctttaa gttttaactg aggatgttgc
    40921 gccaaagggt gctgtttgag gagaacgata ctgaccttat agccttttgt ggacgtttgt
    40981 agtagctcaa tggtaatatc cttttgaata cttagaaagg agaggagacc aatatcgatt
    41041 tttccttggg acaataattc ttataatttg cgagaaccat cctgtataag cgataattca
    41101 acatttgagt gagtagccat aaagattgaa atttgtttca tgaattgtat agcaaacagt
    41161 gatgttaatt caacacgaat catctctttt tttcttgatt taattgctga atatccgcaa
    41221 caatttgatt aaagtcatcc acaaggtctt tgcctttgtg ataaagaata tctccagctt
    41281 cggttagtag tagctgtcaa tcactttgtg taaaaagcgt cgtgttcaaa ctaggactct
    41341 agccttttaa ttgattgaga aagagtatgt tgcgttacaa acaaactttt agcagcgtgg
    41401 gaatgatttt ttgtttcagc aactgcaata aaataggtta attatctaat atccatagta
    41461 gatccttcat gattggtcag ggaattgcgt ctctacttgg tttacaacct attttgatgt
    41521 ctctccttat tgccatgatt ttctgcttcc ttattgtttc tccaattgca acggtaggaa
    41581 ttgctcttgc gattaactta tctggtattg gttcaggtgc cgcaagcttt ggactttgct
    41641 tagcaggttg ggctgttaat tcaaaaggaa cttcacttgc tcacgtcttg ggatcaccga
    41701 aaatttcaat ggccaacgtt ttatcaaaac caaaaatcat gttgctaatg ttatgttctg
    41761 cagctgtact tggtgttatt ggtgctatct ttaatattca aggaacacct gctagtgcag
    41821 gctttggaat tagtggtttg atcggaccta tcaatgccct taatttagct aaaggcggat
    41881 ggtctccagt aaatattcta cttatcattg tcatttttgt aggggcacca attgttctca
    41941 atatgatctt taactacctt tttatcaagg tgcttaaagt gattgatcca atggattaca
    42001 aacttgatat ctaagaaagg aacttttgat gaaattaaaa ttatataatg ttagaggcga
    42061 agaagcagtc ttagcaaaaa aatgggctga tgacaatggg attgagattt ccttgacgga
    42121 gtctccctta actcctgaaa cggttaaaga agctgaaggc tttgacggga ttgccaatgc
    42181 ccaaattggt cctttagatg atgcgattta tcctctctta aaggaaatgg ggattaaaca
    42241 aatcgctcag cgcagtgctg gtgtcgatat gtataacctt gatttggcca ccgaaaatga
    42301 cattattatc acaaatgttc ctagctattc tccagaatcc attgcagaat ttacggttac
    42361 tattgccctt aatttaattc gtcatgtgga gttgattcgt gaaaatgtta aaaaacaaaa
    42421 tttcacttgg ggactcccta tccgcggccg tgttttaggt gatatgacag ttgcgattat
    42481 cggaactgga cgtattggtc tagctactgc taaaatcttt aaaggttttg gccgcaaggt
    42541 cgttggatat gatatttacc aaagcgatgc tgccaaagct gtcttggact ataaggaatc
    42601 tgtagaagaa gcgattaaag atgctgatct tgtttcctta cacatgccac caactgcaga
    42661 gaacacacac cttttcaatt ctgatttatt taaatcattc aaaaaagggg ctattttgat
    42721 gaatatggcg cgtggtgccg tcattgagac gcaagattta ctggatgctt tggatgcagg
    42781 cttactgagc ggagctggta ttgacactta cgaatttgaa ggaccttata tacctaagaa
    42841 ttttgaaggt caagaaatta cagattcact atttaaagct ttgattaacc atcctaaggt
    42901 tatttatacg cctcatgcag cttattatac tgatgaagcc gttaaaaacc tagttgaagg
    42961 tgcccttaat gctacagtag agattatcaa aactgggaca acgacaactc gtgttaacta
    43021 acaactgatt tgacgtccat tataaaggaa taattttaaa aattccttta taatggactt
    43081 ttttatatta gtccgttata atagactgta agaaagggga ctcttatgac atatatagcg
    43141 cttattggag atattatcca gtccaaacaa ttgacggatc gttccaaagt tcaaaaaact
    43201 ttagcagctt atttagacga cctcaacaaa acctttgctc cttatattat ttctaaatta
    43261 tccctaacgt tgggagatga atttcaagga ctttttcagg tggatactcc tattttccat
    43321 ctgattgatt tgattaatca tcacatggat atccctattc gatttggagt aggagtaggt
    43381 tctattctaa cagacatcaa tcctgatatt agtattgggg ctgatggacc tgcttattgg
    43441 catgctcgtg aggctattcg ttatattcat caaaaaaatg attatggtaa tactacatta
    43501 gctcttcgga ctggtcatca caaccaggat gatgtattaa acagtttact agcagctgga
    43561 gatgctatta aagccaactg gcgagctagt caatgggaaa tttttgacac gcttttagat
    43621 ttgggcattt atgaggaata ctttgatcaa caacgactag gaaagcaatt atctcttagc
    43681 tctagcgctt tgtcaaaacg tctaaaaagt agtcatgtta aaatttatct gagaacacgg
    43741 cagagtgcgc taaactgtct caaacaaatc aaggaggaag ctgatgatta atggtgtctc
    43801 tcactaccta gctcaaaccc ctacacttac cctgtttctc atttgtcatg tgttatcaga
    43861 ctaccagtta caaagtcagc aagtagctga tttaaaagaa aaacatttga cttatttagg
    43921 ttaccacttg attggagtta gcattcccct aatttgttta accctcatta tcccacaagc
    43981 atggttgatg agcctattgg ttatgataag tcacgcgctt attgactggc taaagccaaa
    44041 gatggctaac tctctaaaat ggaaaagaga gtggattttt ctgctggatc aatgcttaca
    44101 tatcgctatt agttcatttg ctgggctaag gttagcaggg atgaccttgc ctaattggct
    44161 tccgatatct attttgatga ccgttttatt tatcctactc attaccaaac caactaatat
    44221 tgtctttaaa ctctttttca gcaaatacca gcctgaccaa ggagaaaaaa tggacacgat
    44281 cataggagcg gggctaccat aggaattcta gagagaattg ttattggggt gtgtatgatc
    44341 atggggcaat ttgcttcaat aggtctggtc tttaccgcta aatctattgc tcgctataat
    44401 aaaatttcgg aaagtccagc ttttgcagaa tactacctaa ttggttcttt atttagtatt
    44461 ctcagtgttt ttatcgcagc atggatttgt ttcttctagt tgaaaagggt tcccgtagaa
    44521 agaggctaca catagcctct tttgcttttt tcccctttct gttataataa gtcaggtaac
    44581 tacattagaa agatttgtgg gtctgtcatc taagagatgt cattcccgaa gaggtattag
    44641 tgacttgtct caatcaactg caacttatat taatgttatt ggagctggac tagctggttc
    44701 tgaagctgcc tatcagattg ctaagcgcgg tatccccgtt aaattgtatg aaatgcgtgg
    44761 tgtcaaagca acaccgcaac ataaaaccac taattttgcc gaattggtct gttccaactc
    44821 atttcgtggt gatagcttaa ccaatgcagt cggtcttctc aaagaagaaa tgcgtcgctt
    44881 ggattccatt attatgcgta atggtgaagc taatcgtgta cctgctggag gagcaatggc
    44941 tgttgaccgt gaggggtatg caaagagtgt cactgcagag ttggaaaatc atcctctcat
    45001 tgaggtcatt cgtgatgaaa tcacagaaat tcctaacgat gccattacgg ttatcgcgac
    45061 gggaccgctg acttcggatg ccctggcaga aaaaattcac gcggtaaatg gtggcgatgg
    45121 attctatttc tacgacgcag cagcgcctat cattgataaa tctactattg atatgagcaa
    45181 ggtttacctc aaatctcgct acgataaagg cgaagctgct tacctcaact gccctatgac
    45241 caaggaagaa ttcatggctt tccatgaagc tctgacaacc gcagaagaag ccccgctgaa
    45301 tgcctttgaa aaagaaaagt attttgaagg ctgtatgccg attgaagtta tggctaaacg
    45361 tggcattaaa accatgcttt atggacctat gaaacccgtt ggattggaat atccagatga
    45421 ctatacaggt cctcgcgatg gagaatttaa aacgccatat gccgtcgtgc aattgcgtca
    45481 agataatgca gctggaagcc tttataatat cgttggtttc caaacccatc tcaaatgggg
    45541 tgagcaaaaa cgcgttttcc aaatgattcc agggcttgaa aatgctgagt ttgtccgcta
    45601 cggcgtcatg catcgcaatt cctatatgga ttcaccaaat cttttaacgg aaaccttcca
    45661 atctcggagc aatccaaacc ttttctttgc aggtcagatg actggagttg aaggttatgt
    45721 cgaatcagct gcttcaggtt tagtagcagg aatcaatgct gctcgtttgt tcaaaagaga
    45781 agaagcactt atttttcctc agacaacagc tattgggagt ttgcctcatt atgtgactca
    45841 tgccgacagt aagcatttcc aaccaatgaa cgtcaacttt ggcatcatca aagagttaga
    45901 aggcccacgc attcgtgaca aaaaagaacg ttatgaagct attgctagtc gtgctttggc
    45961 agatttagac acctgtttag cgtcgcttta acactaaaaa agagttcctt ttcagttgag
    46021 ttgctgaaga ggactttttt atttgctgat ttgagcgcta gctatgcaaa agaatgcaca
    46081 aaaaatacat gaatagacta tggtcactag aagcaatatt atataatgaa tagtactcat
    46141 tagttgattc agtttggagg ttttagcatg cagcagcaag tcgcaataac agaaacagtt
    46201 ttacgggacg gtcatcaaag tttgatggca acgcgtttat ctattgagga tatgcttcct
    46261 gtccttacca tcttagacaa gattggttat tattccctag agtgttgggg aggagcaacc
    46321 tttgatgcct gtattcgttt tttgaatgaa gacccttggg aaaggctgcg cacgttaaaa
    46381 aaaggcttac ctaatacccg tttacaaatg ttattaagag gccaaaacct tttaggctac
    46441 cgtcattatg cagatgacat cgttgacaaa ttcattagtt tatcagctca aaatgggatt
    46501 gatgttttcc gcatttttga tgccctaaat gacccacgaa atatccagca agccttaaga
    46561 gctgtgaaaa agacggggaa agaggctcaa ctgtgtattg cctatacaac tagcccagtg
    46621 cacacgctta actattacct ttctttagtg aaagaattgg ttgagatggg agctgattct
    46681 atctgcatca aagatatggc tggtattcta actcccaaag cggctaaaga gttggtatct
    46741 ggtatcaaag ccatgactaa cttacctctt attgtgcata cccatgcaac tagtggcatt
    46801 tctcagatga cctatctagc agcagtagaa gctggtgctg atagaattga taccgctttg
    46861 tcacctttta gcgaaggcac ttcacaacct gctacagaat ccatgtattt agccttaaaa
    46921 gaagcaggtt atgatatcac attagatgaa acgctactgg aacaggctgc taatcacctt
    46981 cgacaagccc gtcaaaagta cttagcagat ggcattctgg atcccagtct tctctttcca
    47041 gacccaagga cactacaata ccaagttcct ggaggcatgt tatctaatat gctatctcag
    47101 ctgaaacaag ccaatgccga atcaaaatta gaagaagttt tagcagaagt tcctcgggta
    47161 agaaaagact tgggttatcc tcccttagta acaccgctta gccaaatggt cgggactcaa
    47221 gctgctatga atgtgatttt aggaaaacct taccagatgg tgtctaagga aattaaacaa
    47281 tacttggcag gcgactatgg caaaacacca gcaccagtca acgaagactt aaaacgaagt
    47341 caaattggct cagctcctgt caccacaaat cgtcctgcag atcaactaag tcctgaattc
    47401 gaagtgttaa aagcagaagt agcagattta gcccaaacgg acgaagatgt gctgacttat
    47461 gccctcttcc caagcgtagc aaaaccgttt ttaacaacca aataccaaac tgatgacgtc
    47521 attaaagtga ctgcctttat caaagcataa taggctatct taatcagata gaaacaaaaa
    47581 tatggagatc aaatgaccta ttcctttatt gatatcttac aagttacctt agtatccttg
    47641 ttcttagtgt taacctgttt aacagggatt atgggattaa tgatgctaag tggtaaatta
    47701 ttgtcacaag aaaaaaaaac tctctctcaa caagcttcca gcattcctca agagcaagaa
    47761 gctgacaagt tgagtggaga agctctcgaa actcttttag ccaaagacga attggctaga
    47821 attgctgtta tgactagtct tgcttatgct agccaagaag agtcaggaaa acggtttgaa
    47881 gttattgccg tggaaaggaa atcctaatga aaagatatga agtgactgtc aatggacagg
    47941 tttatgaagt gagtttacgt gaactagctg atggagaaac tgttgaagtt agccagccag
    48001 cagcacccgc tactgagaaa gaaatgaatg ccaacgctgc tggcggtggc attcaggtaa
    48061 agactccaat gtctggaaca gtcttgtcta tctttgctac agaaggaaaa gctgttaaaa
    48121 aaggagaagc tgttctggtc ttagaggcca tgaaaatgga gaatgaaatt ctagcacctg
    48181 cagatggtct ggtttcaaaa attcatgttg tggctaacca aacggtcgag tctgaacaag
    48241 ttttgatttc attctaggag gaaaccatgc tagacgtact caatcaaatg gtccaatcgt
    48301 caggattggc tcatctaact gttaataatc ttatcatgat ttgcttggcc tgtttctttt
    48361 tataccttgg tatcaaaaag gaatatgagc cttaccttat ggtaccaatc gcctttggga
    48421 ttttactcgt taatttgcct atggcgggat tgatggacca ccctgccaat ggtaatcctg
    48481 gtggccttct ttattaccta tataagggaa ctagcctagg gatttaccca cctttaattt
    48541 ttctttgttt gggggcatca actgactttg gtcccttgat tgccaatcct aaaaccattt
    48601 tactaggagg cgcagcacaa gttgggattt tcttagcctt tttccttgct attatgttag
    48661 gcatgacacc tcaagaagcg gcttctgtcg ggattattgg tggtgccgat ggaccaacag
    48721 ctatttatgt gacgacaaag ttggcgcctg atttactctc tactatcgcc ctagcagctt
    48781 attcttacat ggctctggta cctattattc aacctcctat cattaaactc ttgactacca
    48841 aggcggaacg ccaagtgaaa atgactcaag caagaactgt ttcacaaaaa gaaaaaatca
    48901 ttttcccgat tatggtaaca atctttgtca gccttttggt tccaagtgct acaaccttgg
    48961 ttggctgttt gatgctggga aatctggtca gagaaattaa aattgttcct aaaattgtag
    49021 agaatctcca acaagtggtt atgttttgca ttactatcat tttagggtta accgttggtg
    49081 ctaaggccaa tggagatctc tttttatcag ccacaacctt gaaaattatt gcccttgggc
    49141 taatcgcctt tgctgctggt acagcagggg gtgtcttgat ggggaaggtc atgtactatt
    49201 tatctggtaa caaagtgaac cctatgatag gagcagcagg tgtttcagct gttccgatgg
    49261 cagcgcgagt ggtccaaaag gtcggacaag aagaagatcc aagtaatttc ttactcatgc
    49321 acgccatggg gcccaatgta gctggcgtta ttggctcagc cattgcctca ggtgccttgc
    49381 tggccttctt tggctaattg tgaaaaagga ttagtaaatt aatcttaata aatcattatc
    49441 aggagttgga agcaatctag ctcctttttt agtagaaagc tcgagtgata aactattcca
    49501 aaataattat aaaaaaagac tgtcctgatt gtacggacta tatcaattga cttttatagt
    49561 ctagctgaaa tagcagtgca aaactaagac actcgtttta aagtagtttt tctaaaaaag
    49621 caaaataaaa ggtcagagcc aataaatctg ccgcgccccc agggcttaaa tgctgattaa
    49681 tgaggcattg attgtaggag gacaaagcca atcttaggtc agttgttgat aaatcttgtt
    49741 gcaggagtag tcgcatatct gctttaacgc ctttccatgc ttcaatccct ccacgatgaa
    49801 tcagatttcc atcttcaaca atagacatca aataaacaag aagacgaagc tgactggttt
    49861 cggggtcatt ttgacttatc atctgacgaa agtagggcaa ggcatggtct gttaaggtcg
    49921 tgaatccctc gcttgcctca ccccgaggtc ctttgatgcc ataagttaca aagagttgct
    49981 ccccataagt gaactctttt ttagtgttca aatgaccaag gtctgtttga atcaaatgtg
    50041 ccgtcatagg ttttactaaa cgacagatag ctagagtatc ttccttgcta aaacacccta
    50101 aatcagtcat taagtgaggt gttcttgcta gataggcccc agttgcacca agaagtaaag
    50161 ccatggaaaa attcaggcct ttatgagtgt taattccctg agtagcacaa aacatggttt
    50221 cctcggcctt ttgacctagt tgtctaagac ggttaaacag aagaagtggc tcttcttttg
    50281 cataagcaaa acctgtttcg atataagcct gaaaaaaagg agagagtgct atcatactgt
    50341 cgataaaggt cataaaggac atgtcatcat gggcaccgtt atcaaatcga tcaactaaac
    50401 caggttttgg agatagtgag acttcataaa gcaaagcttt taaggccagt tgactaatac
    50461 ttgttagaac tgccttagtc attttgctca ggcctcattt cttttaagat aaattcaagt
    50521 gagctattca agtgttcatg tgtaatcaac gtaatttgct catgatcttt gttcttcata
    50581 cctcggtaaa tcatccagtg ttcagataga gctcgtttac ggcgttcaac tgaagaaatc
    50641 gaaatttttc taaagtagac caaataagct tgcaattctg tcacaatttc ttttaagcgg
    50701 accatttggc tatagctgta aatcaaattg ttaaaggcat taaaattatc caaaatacga
    50761 ttggtgtcat cctctgcgat aaaggtttca cagtcttcca acaagttatg cataacttta
    50821 aaatcttctt ctgtcattaa atgcatcgct tgcactgttg cgagagtctc tagagctttt
    50881 cgaatttcaa aaatttcaca ggcatccttg atactaactc ctttgacaat aatgcctttt
    50941 ttaggaatgt gctctacaag gtgttcttca gacaataatc ccaaagcgta gcgaataggt
    51001 gtcctgctaa tattaagcgc aatggaaaac tctttttcat taatgcggct tccaacagga
    51061 atttgtcgca aaataatggt ctttttaaga gcgttataaa aggctatttt caaagggata
    51121 tttcttgata ggtcaagatt ttgtttaacg gcttcgataa taggattcat gtcatctcct
    51181 taatgctagt gtcctcactt tattatactt aaatttgtga aacattccaa taggactaga
    51241 tgagttctga aaaattaaag ccatgctcac aaaaggacat gactttaatc atctcataag
    51301 gaataaggta gtagtgttat cgttggttta ttgtggaatg taaagtggca tttgccccat
    51361 ggcaataatg gttaccacaa agataacaaa gatgataagg gcatatttag cagcctcttt
    51421 ttgccattcc cccatgtcaa gacctgtcaa gcgaagaaga agataaatga aggcaactaa
    51481 tggactaagt aagtggaagg cttgtcccat gagggaagca agtgccatag ccatgttact
    51541 gaaaccatat tcagcaccag cttctgcaag aacaggcaag ataccatagt aaaaaccatc
    51601 attggagata aagaaggtac caggtgcaga aactaaggca ataacaagac cccagaaacc
    51661 tgccagttgt tttggaataa tggttgcaaa actttgtgca agagcgctag ccataccaga
    51721 accttgaaaa agacccataa agataccagc agcaaagacg agaataacca cttgaaccgc
    51781 atcaccagca ttgtcaccaa tgcgttttga ttgatcttta agtactgggt aattgaccat
    51841 caaggcgata caagttccca ccgcaaaaag aagaagcggt gccatagcaa tagatttgtt
    51901 gaaagagcca gcaactaacc aagtgattaa tccaatggtt aggatagcat tgaaaacaaa
    51961 gtttttagga cgacgaataa aaagggtatc tgggtcagta atgtctgtga gttgacgcat
    52021 gtcttcttca gacaagtcaa taacaccaag tcttgcacgt tctttacgcc ccatgcttgg
    52081 agcaacccaa caaatcacat aaagaagaga taaaatcata cccggtgcaa gatagccaag
    52141 aatttcagga ccgacaccaa gaacagacat cgcacgagca gtagggccac cccatggcag
    52201 taagttcata atagtatttt gaagaataat caagacacct aggttcatga ttttcatgtc
    52261 caatttttta tagataggta agaaagcaga gcaacaaatt aaagtagtgg ttgttccatc
    52321 accattaaga gatactgcag cagcaacgac agctgttgcg ataagcacct tcattggatc
    52381 acctttagca aagcgaatca tcttttcagt aatcggatca aacaatcctg catctaacat
    52441 gacagagaag aacaaaatgg caaatagcaa catgatacct gttttagcag tattgttgat
    52501 accatacata accattggtc cgatagctgt taggtcttta gcaattccac cgtcaccaac
    52561 aaaggcaaca aatttggcat ctgcattgaa gtcagctgaa ccagtcagta taacagcaat
    52621 cgtcatgatt aatggaatca tgaccaaagc agtaaaaggg gtcatttttt tcttcattac
    52681 cacgtacata aagacaataa tcatggcata agccagcatt gttaataaca tcattgttat
    52741 ctcctttttc aagttatgat ttcagtatag atgaaagcgc ttataaaata aatacttc
//
LOCUS       DAUGOH010000010        52067 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUGOH010000010 DAUGOH010000000
VERSION     DAUGOH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52067
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.010"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(224..856)
                     /locus_tag="VH957_000607"
     CDS             complement(224..856)
                     /locus_tag="VH957_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEQ8558544.1"
                     /translation="MVENTKLLCSWGWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            complement(856..1620)
                     /locus_tag="VH957_000608"
     CDS             complement(856..1620)
                     /locus_tag="VH957_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEQ8558545.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHVETSIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            complement(1620..2372)
                     /locus_tag="VH957_000609"
     CDS             complement(1620..2372)
                     /locus_tag="VH957_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEQ8558546.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGD
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            complement(2382..3512)
                     /locus_tag="VH957_000610"
     CDS             complement(2382..3512)
                     /locus_tag="VH957_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEQ8558547.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTITNLKAAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            complement(3575..4216)
                     /locus_tag="VH957_000611"
     CDS             complement(3575..4216)
                     /locus_tag="VH957_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558548.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKQDT
                     QNRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLHAKGCKPGNENDSDVCQLLKYFSKP"
     gene            complement(4340..5695)
                     /locus_tag="VH957_000612"
     CDS             complement(4340..5695)
                     /locus_tag="VH957_000612"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEQ8558549.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     AKIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            complement(5749..6705)
                     /locus_tag="VH957_000613"
     CDS             complement(5749..6705)
                     /locus_tag="VH957_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEQ8558550.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            complement(6702..7553)
                     /locus_tag="VH957_000614"
     CDS             complement(6702..7553)
                     /locus_tag="VH957_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEQ8558551.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            7660..9003
                     /locus_tag="VH957_000615"
     CDS             7660..9003
                     /locus_tag="VH957_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEQ8558552.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     ERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFVCLNCQFQRPTLDYQLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITHMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIMEAIEKQESKHAYILATYTAMLEFRSLLADRHVVEKEMN"
     gene            9003..9794
                     /locus_tag="VH957_000616"
     CDS             9003..9794
                     /locus_tag="VH957_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEQ8558553.1"
                     /translation="MTYTSLKSPEKTDYLYDLNIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGARVTVDIVSLNDAFDQDYYDLVFFGGGQDYEQTIVAKDLPSKKAALADYIAKNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(9903..10892)
                     /locus_tag="VH957_000617"
     CDS             complement(9903..10892)
                     /locus_tag="VH957_000617"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8558554.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILAKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            11125..13542
                     /gene="hylA"
                     /locus_tag="VH957_000618"
     CDS             11125..13542
                     /gene="hylA"
                     /locus_tag="VH957_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEQ8558555.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTPTTTDSEKKVVQSQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASANITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTTPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTFVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATTFSNHSLSHQGFYSFPH
                     PVKQNQQ"
     gene            complement(14217..15980)
                     /gene="lpdA"
                     /locus_tag="VH957_000619"
     CDS             complement(14217..15980)
                     /gene="lpdA"
                     /locus_tag="VH957_000619"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEQ8558556.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAM
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(16307..17716)
                     /locus_tag="VH957_000620"
     CDS             complement(16307..17716)
                     /locus_tag="VH957_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEQ8558557.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPTVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKVAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLACKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(17901..18899)
                     /locus_tag="VH957_000621"
     CDS             complement(17901..18899)
                     /locus_tag="VH957_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEQ8558558.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(18958..19926)
                     /locus_tag="VH957_000622"
     CDS             complement(18958..19926)
                     /locus_tag="VH957_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEQ8558559.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(20211..22118)
                     /locus_tag="VH957_000623"
     CDS             complement(20211..22118)
                     /locus_tag="VH957_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8558560.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQEALME
                     EWETIAEQIES"
     gene            complement(22164..22490)
                     /locus_tag="VH957_000624"
     CDS             complement(22164..22490)
                     /locus_tag="VH957_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558561.1"
                     /translation="MKQLLAIILWLPKLIVKLFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(22520..23305)
                     /locus_tag="VH957_000625"
     CDS             complement(22520..23305)
                     /locus_tag="VH957_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEQ8558562.1"
                     /translation="MANIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPKTLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFAANEKAIADF
                     RAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(23438..25099)
                     /locus_tag="VH957_000626"
     CDS             complement(23438..25099)
                     /locus_tag="VH957_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8558563.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKDKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            complement(25303..26061)
                     /locus_tag="VH957_000627"
     CDS             complement(25303..26061)
                     /locus_tag="VH957_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558564.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(26058..26927)
                     /locus_tag="VH957_000628"
     CDS             complement(26058..26927)
                     /locus_tag="VH957_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558565.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERFFKGVRLTR"
     gene            complement(27272..28270)
                     /locus_tag="VH957_000629"
     CDS             complement(27272..28270)
                     /locus_tag="VH957_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8558566.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANRQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAIKREDFPSASFIEN"
     gene            28624..30276
                     /gene="fbp54"
                     /locus_tag="VH957_000630"
     CDS             28624..30276
                     /gene="fbp54"
                     /locus_tag="VH957_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEQ8558567.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSEMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(30335..31582)
                     /locus_tag="VH957_000631"
     CDS             complement(30335..31582)
                     /locus_tag="VH957_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEQ8558568.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDLEGLTEVAREKLLQAVAISSEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLMYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(31572..32753)
                     /locus_tag="VH957_000632"
     CDS             complement(31572..32753)
                     /locus_tag="VH957_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8558569.1"
                     /translation="MPLIPDKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINRLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(32811..33287)
                     /locus_tag="VH957_000633"
     CDS             complement(32811..33287)
                     /locus_tag="VH957_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEQ8558570.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(33508..34548)
                     /gene="rfbB"
                     /locus_tag="VH957_000634"
     CDS             complement(33508..34548)
                     /gene="rfbB"
                     /locus_tag="VH957_000634"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEQ8558571.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(34792..35385)
                     /locus_tag="VH957_000635"
     CDS             complement(34792..35385)
                     /locus_tag="VH957_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEQ8558572.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYALVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(35385..36254)
                     /gene="rfbA"
                     /locus_tag="VH957_000636"
     CDS             complement(35385..36254)
                     /gene="rfbA"
                     /locus_tag="VH957_000636"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEQ8558573.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(36312..37418)
                     /locus_tag="VH957_000637"
     CDS             complement(36312..37418)
                     /locus_tag="VH957_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEQ8558574.1"
                     /translation="MKIAIVGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDTYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLWSAGKA"
     gene            complement(37458..38246)
                     /locus_tag="VH957_000638"
     CDS             complement(37458..38246)
                     /locus_tag="VH957_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEQ8558575.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISIYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(38236..38922)
                     /locus_tag="VH957_000639"
     CDS             complement(38236..38922)
                     /locus_tag="VH957_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEQ8558576.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(38994..39650)
                     /gene="nth"
                     /locus_tag="VH957_000640"
     CDS             complement(38994..39650)
                     /gene="nth"
                     /locus_tag="VH957_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEQ8558577.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(39647..40330)
                     /locus_tag="VH957_000641"
     CDS             complement(39647..40330)
                     /locus_tag="VH957_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ8558578.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFHLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(40411..40929)
                     /locus_tag="VH957_000642"
     CDS             complement(40411..40929)
                     /locus_tag="VH957_000642"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEQ8558579.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(41080..43290)
                     /gene="recJ"
                     /locus_tag="VH957_000643"
     CDS             complement(41080..43290)
                     /gene="recJ"
                     /locus_tag="VH957_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEQ8558580.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKAWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(43287..44051)
                     /locus_tag="VH957_000644"
     CDS             complement(43287..44051)
                     /locus_tag="VH957_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ8558581.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKIVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAKEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFNQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(44051..44980)
                     /locus_tag="VH957_000645"
     CDS             complement(44051..44980)
                     /locus_tag="VH957_000645"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEQ8558582.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(44995..45630)
                     /locus_tag="VH957_000646"
     CDS             complement(44995..45630)
                     /locus_tag="VH957_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEQ8558583.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(45623..46861)
                     /gene="hflX"
                     /locus_tag="VH957_000647"
     CDS             complement(45623..46861)
                     /gene="hflX"
                     /locus_tag="VH957_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEQ8558584.1"
                     /translation="MVETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(46934..47833)
                     /gene="miaA"
                     /locus_tag="VH957_000648"
     CDS             complement(46934..47833)
                     /gene="miaA"
                     /locus_tag="VH957_000648"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEQ8558585.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYEFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGTVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDCINQRVDHMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            47967..48143
                     /locus_tag="VH957_000649"
     CDS             47967..48143
                     /locus_tag="VH957_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEQ8558586.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(48261..49169)
                     /locus_tag="VH957_000650"
     CDS             complement(48261..49169)
                     /locus_tag="VH957_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEQ8558587.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFNYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FWGNLVLIAYYQYRFVFSFSWDNVSPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(49406..49825)
                     /locus_tag="VH957_000651"
     CDS             complement(49406..49825)
                     /locus_tag="VH957_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEQ8558588.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLADSRFNEIMDYLTGDFPFVFRPMF
                     NPHRYTISQDNQALEKVKQASYKRMGIAMTHLDGLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKIVEDSAVQQVLNAAH"
     gene            complement(50136..51122)
                     /locus_tag="VH957_000652"
     CDS             complement(50136..51122)
                     /locus_tag="VH957_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEQ8558589.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGV"
     gene            51318..51620
                     /locus_tag="VH957_000653"
     CDS             51318..51620
                     /locus_tag="VH957_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558590.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKCKYKDYPIKIETFLL"
     gene            complement(51983..52054)
                     /locus_tag="VH957_000654"
     tRNA            complement(51983..52054)
                     /locus_tag="VH957_000654"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52019..52021),aa:Arg,seq:ccg)
BASE COUNT        15826 a        11078 c         9153 g        16010 t
ORIGIN      
        1 tccttgatta tttgttataa aagttataaa ataatcttgt tggaaccatt caaaacagca
       61 tagcaagtta aaataaggct agtccgttat caacttgaaa aagtggcacc gagtcggtgt
      121 ttttttgata cttctattct actctgactg caaactaaaa aacaagcgct ttcaaaacgc
      181 ttgttttatc atttttaggg aaattaatct cttaatcctt ttatcattct acatttaggc
      241 gctgccatct tgctaaacct actaagctcc acaggatgat ttcgtaaact atcataaaga
      301 aaaggaaaca gtgcaagaaa aagacttctg gaaggatcca aatcacagga tctttcaagg
      361 gatcaaagag ccagctgcta tctcctacaa aaagcacctg atgaaaaaga gtaaaaaaat
      421 gttcaaaccc aatgaaacta gccattagac caatcataag aggaaacaaa gctgctagta
      481 ttaaaggttt ttgaaggagc cagaaacgtt tggtttttaa cctttgtgtg aaagtcttaa
      541 gggttgggta aaggaggcca agaaaaacga cttgagttag gtgaaaaagc cacttcacat
      601 ctgcaaaatg cttgagtccg tctgctgacg agtgaaaatt agcaaattcc aaccttgtta
      661 caaaaggatt ggtaaggtaa tttagtagtc cgttatagtt atgcaagata gcatccttgc
      721 tcataaaaac aacttgttct aactttagat ggtccacctc aagaggatac cacagccacg
      781 ttgaatagat cgttatgaga atagctaatg ctaataacca tccccagcta catagtaatt
      841 tagtgttttc taccatcaca acctccactc atcaagacta gataggacat gatctggctg
      901 aattggtaag gttggtacct cttcaggtct ggtaaagcct gttgtcacga ggatcgttgc
      961 aatatcattt tgaatacctg ccatgatatc agtcaagtaa ttatcgccaa ccataacggc
     1021 ttcagagcgc tgaatgccca atacctctag tgatttattc ataatgatag cgttgggctt
     1081 gccaataaaa acaggtttta cacgtgtggc agcttctagt aaggcattca atgcacctgc
     1141 tcctggcatc aaaccacgtt cggttggaat gtttaaatca ggatttgtcc caataaagag
     1201 ggcacctttt tgaatagcca aggtggctat agccaacatc tcataggtca cctgactgtc
     1261 taaaccaacc accacgtaag cgggattctc aagttcttct acgtaacctg ctgctgcaat
     1321 cgctgatttg agccctgttt ctccaataac gtaagctgtc ttgccacggt tcatgtcatt
     1381 catgtaatcg acggttgcca tggtagccgt ataaatggtc tcaatgcttg tctcaacatg
     1441 aaactgatta gccagcatgc tttgcaccat ttcgggtgtt cttgtggtat tattagtcac
     1501 taataaatag ggaatgcctc tttcttgtag gcgtttgata aaccgctccc ctgctggaat
     1561 acggtttttc ccttggtaaa tcgttccgtc taaatcaatt aaataaccct tataaggcac
     1621 tagtctgtct cgctttctgt ttgtttaatc gctcgccatt caatcatggc ttgggcattc
     1681 agctgcccat ctgaggtgat ttgatggtaa gaagttaatt ggtccaaatg gtaactggaa
     1741 gtaatttgac cgcctggtga gacttcttta acatatttca aagtcatctt aagaggctga
     1801 tgcgttttta aaaactcaca ccccaacaca tcatacatcc aatctaaata tttactgttg
     1861 ttgacatgac cattcatatc aatatcaaaa taacgcacat aataatcacg atcaattgat
     1921 tgttctaaaa gaggcatttt aggaacacgg tgtagctttt taacaaaatc agtcttaaaa
     1981 ggcgctacta aatcttctgg aatagttgcc acttttcgcg tatctgggtt taacaaagca
     2041 aaataggcta agatatccac taaaagatcc ccctcttgat cataaatata aaattggcga
     2101 taacaaaaaa atttattgta ggagagggct tttgtttcaa tggtgatggt ttcttgaaaa
     2161 tgtggcaagc gatgaatagt gatctcataa tccgttacaa tccaaacaag cttgtaatcg
     2221 actaaaagat tgttgttact tcgtcctaat tgcgcagact gtctaccaga aaccatcaaa
     2281 caatagtcta ataaaagggg caattttata tctgatttga catcacataa ttcaaaagga
     2341 agtgtcaact cctcctgata acttaatccc ataatactct cctaatctaa tataaaccgc
     2401 tcagcaacag aatcacctaa gaaaagaccc tttttagtca ttctgacaaa agcgtcatct
     2461 ttgacaagca gtccttggtt ttgaagctcc ctaacaatat ttccataacg ctcctcaaaa
     2521 gacataccaa atttttcttg gaaccgctgg atggagactc ctgtcttttt acgtaagccc
     2581 aaaaagagtt cctcttccat catttcctct ttgcgcagca cttcttcatt tagtctagcg
     2641 tttcctgctt caaccgcttt aagataatgc tggatgggca cccgattttg ataacgaatg
     2701 ccattaaggt aacctgaagc ccctgcacca catccaaaat actccacatt atcccaatac
     2761 atcaagttat ggcgactttc aaaacctggt ttggtaaaat tggaaatttc ataatgctca
     2821 aaaccattag cttccatttc tgaaataata tactcaaaca tttccgcttc caagtcttcc
     2881 gttggtaagt taagtttacc acgccgcatt ttgttcataa aaacggtgtg atgttccaaa
     2941 ataaggctat aaagactaag atggggaata tcaagtgcca aagctttagc aacattttcc
     3001 ttgacttgat ctaaggtttg acctggcaag gcataaatta aatcaatgga aatattgtga
     3061 aagcctgcag cttttaaatt agtgatggtg ctataaattt gttcttcatt atggctacgg
     3121 ccaatctgct ttaattgctt gttattaaaa gtctgcaccc ccaaggaaat ccgattgaca
     3181 gctgacctct gaagcaccgc aattttttct ggcgtcaaat caccaggatt tgcctcaatt
     3241 gtgaattctt caagatcatc taaattgagg tttcgttcaa ggtgatttag gagatactcc
     3301 aactgtttag cagtgatagc tgtaggcgta cctcctccaa tataaagggt ttttaggtct
     3361 cgaatgccat aagagtcaaa ttcttgaatc aaggctttca aataagcatc aacaggttga
     3421 ttttggataa agacttttga aaaatcgcaa taataacaaa tttgtgtgca aaaaggaatg
     3481 tgcacatagg ctgaagtagg tttttttgac atggtcttat tataccactt tgatgataaa
     3541 atgtttctat gaataaacca tttcccttga ttcctcatgg cttggaaaag tattttaaga
     3601 gctgacaaac gtcagaatca ttttcgtttc ctggcttgca acccttagcg tgcaaaacaa
     3661 acccttgttc ttggtaaaaa agcttgcttg attcttgact gaccataatg cttaaagaag
     3721 ggagtttctc ttgcatatct gccagaagat atgtctggac agcctccaca atagctgctg
     3781 gaacctcgtt ttctgtcact gtttcaagaa tccctaaagt catttctaga aattccccct
     3841 tttcttgaag aatcacaaag gctactcttg ctccatttcg aagcacttga aaaagcgtct
     3901 gatcctcgtt aacagcagcc gcaaacactt gattagctgc aactgtcgat aacaaatgat
     3961 aagctaggcc tttatctgct agcaattgct ctgctgtttt tcttgtcaca ggcatcacat
     4021 aaaaagatgg ggtatctagt aatcgttcaa aatttttagt taactgcttg atgcgacggt
     4081 tttgagtatc ttgtttttgt gtttgataaa cataagaagc ataaccttct tgaaattcag
     4141 gaatcatatc taagtaaagt gtggctgcaa aaggaggcag taagtccgct agtttttcga
     4201 tttgctgttt tgtcatccga tatcctttct cttctacttt agtaatttat aaaaagagac
     4261 ttgggctaaa cgccccaagc ctctttccaa ttgttgacag aagccttaga aataaggttt
     4321 cttgtttgta ctcaactcgt tagttatcgc atccgatttc tgtacggacg acatcagcaa
     4381 tagtatcgac ataataatca acttcggcat ctgttggcgc ctctgccatg acacgaagaa
     4441 gaggttctgt accacttggt ctcacgagaa tacgaccatt accagccatt tcatcctcca
     4501 tttttgcaat gatcttcgca atagctggaa cttccatagc acggtctttc atgctgtttt
     4561 ccacacgaat attcaccagt ttttgagggt aaatggttac ttcagcagct aattccgaaa
     4621 gtgatttccc agtttccttc atcaccttgg ctaattggat agctgtcaac tgaccatctc
     4681 cagtggtatt gtagtccatg ataatgacat ggcctgattg ttcaccaccg agattgtatc
     4741 ctgagctacg catttcttca accacatagc ggtctccaac tgctgtaatt gctttattaa
     4801 taccttgttt atctaaagct ttatgaaaac cgaggttaga catcaccgtt gtgacaatgg
     4861 tattgtgagc aagaagccct ttttctgaca aatatttacc aatgataaac ataatacgat
     4921 caccgtcaac aatctcgcca gtttcgtcca cagcaatcag acggtcgcta tcgccatcaa
     4981 aggctaaacc aagatctgct cctgtttcct taactaactc ttgaagttgt tctggatgcg
     5041 ttgaaccaac accgtcatta atattaagac catttggttt ttcaccaatg acagcaattt
     5101 ctgcatttaa atctaaaaag acatcacgtg ctgacactga agcagctcca ttagcagtgt
     5161 ctaaggcaac tgtcataccg cttaagtcag tacctgttgt taccaagaac ttttcatatt
     5221 tacgaagtcc ttctggataa tctaccaagg ttccaagtcc ttctgcactc gggcgaggaa
     5281 gcgtgtcctc cggagcatct aagagagctt caatttccaa ttcttggtca tcagctaact
     5341 taaacccatc attcccaaag aatttgatgc cattgtcaag cgcagggtta tgacttgcag
     5401 aaatcatcac acctgcactt gctttttcag ttctaactaa ataagagacg ccaggtgtcg
     5461 ctaaaacgcc aagtttataa acttcaatac caacagatag tagaccagca atcaaggctg
     5521 actccaacat ttctcctgaa atacgggtgt cacgcgccac aaaaacttta ggtctttcgg
     5581 tctcatgttg acttaaaaca taaccaccga atcggcccag tttaaaagct aactcaggtg
     5641 tcagctcaac atttgcttcg ccacgaacac catctgttcc aaaatatttt cccataattt
     5701 atataagcct aatggcttcc tccattcaat tttcctagtt attatccatt attttttggt
     5761 ggttgtcaac tgaacggtca ctactgacgg ctcaattgac acctgactag aagacaaact
     5821 cacggtctta ctagtatttt tagtgacatc agaaatgtta acttctgcaa taatttcatc
     5881 aatatcttct aagacctctc gactacctga gataacagct gtttgttttg acaatttgta
     5941 ttgaatatct gataagctat catccatcat ccccactgcc tcaactctaa tcgggactga
     6001 tttcgttatt ttttttacag caactgataa atttgttttt gcaggatcaa ttgcacttgc
     6061 taaaatagtt ccatcagctg agacagcttg taaggtcact cgactactat aattcctatc
     6121 taacacttga tcatcaggta actttgccac aacgtgatca attaaagcaa tggtagattc
     6181 atcactggtc acttcaacct tattaacccc cgtttcaatt ttgctaattt cataaccatt
     6241 tgcaatttgt ttagcatcaa cgcttcctct aacaggaaat accttagatt cttttttgcc
     6301 aattgtgact gatattttat ctggagatac ggtagctgtc accccagaag ggaggttttc
     6361 tactcttagg ttgacactta ctgtacctgg atgactatgt gttaaatccg ccacaatctt
     6421 aaaattacgt gtatcattgt tcacttcaga atctaatttg atacgattag tggaggttag
     6481 ataaacttcc gcaccataag aatacccact gataaaatat ttgtcactat catacttcat
     6541 atcaattggt acatctttaa ggctatgcgt ataggtttca atcggactat aaatttgcga
     6601 gctagagtta ttatgattgc tcgatgctgc agttaaaaaa aggagaatcg caaaaaagac
     6661 tgataccatt cctaaccaag gacgactatt taaaaatcgt ttcatttaga tttccctcct
     6721 agaattttct tataccatgg taaactaaca tttgaatcac tcatcaggta ggtcctaagt
     6781 accgtttcaa attcatctgt gcttaaatcg tgtaaaaatt ggcctttgcg agttactgaa
     6841 atagctcctg tttcttctga aacaatgata gttagtgcat cagagttttc agataatcca
     6901 atagccgctc tatgacgggt cccaaattct ttggaaattg cctttgattc tgacaagggc
     6961 aagtaggcac aagctgccac aatcttattc tgaccaacga taacagctcc atcatgaagc
     7021 ggcgtatttg gaataaaaat attgatgagt agttgacttg aaatatcggc attcagcgga
     7081 attcctgtcg caatatattc ttgtaaggtt tgagtctgtt caatagcaat cagtgcacct
     7141 atcttgcgtg gacccatata ggccacagat ttaatcaaag catcgaccaa agcagattca
     7201 ctgctgacgt actgtttttg taaaaaaact tgcgtagaac gaccaaattt ctccagtcct
     7261 gcccgaattt caggggtaaa aatgactact cctgcaatta caccataagt aatgacttgg
     7321 ttcattaagt atgtgattgt cgtaaagcca atccactctg caataaaacg aagaaccaaa
     7381 aagaaaatga ccccttgaac taaagacatg attttagttc cagtcaatgc tttaataaaa
     7441 cgataaatca aataagcaac aattagaata tctaaaagat gcactgctag cagccaagga
     7501 tccgcaaata agcttaataa aaatttaata tcgatactag ataaattatt catacaactc
     7561 tcatttctat atcaaaaaag ttattagcta tattatatca tatcatgatc aaagattttt
     7621 ccctatctaa aatcaataaa cttatgataa aatataagca tgaaaatgaa gacattactc
     7681 ggcattattg ctggcaaagc tgctcaatcc attttaacaa aactagggcg aggatctact
     7741 tatcctggtc gattggctct agcttgtaat aaagatattt taaaggattt gtctaaagac
     7801 tatgatattg tggtcgtcac tggtactaat ggtaaaacgt taacaactgc tcttactgtc
     7861 ggtattttga aagaggcatt tggcgagata atcacaaatc caagtggtgc caatatgatt
     7921 actggaatta cttctacttt tttagctgct aaaaaaggga aatctgaaag gcaaattgct
     7981 gttttagaaa ttgacgaggc tagtcttcct agaattacca cttacttaaa acctagtctt
     8041 tttgtttata ctaatatttt tagggatcag atggaccgct acggagagat ttatactact
     8101 tatcagatga ttgtagatgg tgctcgaaat gctccaaaag caactattct agccaatgga
     8161 gatagtccta ttttctcttc taaggacata gttaatccag ttcagtatta tggttttgat
     8221 actgctaagc atgctccgca gctagctcat tacaacacag aagggatttt atgtccaaaa
     8281 tgcgaacata ttcttcagta tcgtctcaat acttatgcga atctaggaga ctttgtttgc
     8341 ttaaactgtc agttccaaag accaacgtta gattatcaat taactgagct caccgctatt
     8401 actcaccaaa gttctgaatt tgttattgat ggacaaaact acaagataaa tgttggtggt
     8461 ctttataata tttacaatgc gcttgctgcc gtctctgttg ctgaattttt cggtgtttct
     8521 cccgagaaaa tcaaggcggg ctttaacaaa agtaaggcgg tttttggaag acaagaaact
     8581 tttactattg gtgataaatc atgcaccctt atccttatca agaatcctgt tggagccagt
     8641 caagcgcttg aaatgattca gctagctgat tacccattta gcttatctgt gcttttaaat
     8701 gccaattacg ctgatggcat tgataccagc tggatttggg atgctaattt cgaactcatt
     8761 acacacatgc caattactga gattaatgct ggtggtgtcc gtcactctga aattgccaga
     8821 agacttagag tcacaggatt tgacgacact aagataaaac aagctgaaaa gctcgagcaa
     8881 atcatggaag ctattgaaaa acaagaaagc aaacatgctt atattttagc aacctatact
     8941 gcaatgttag aattccgtag cttgctagcc gaccgccatg ttgttgaaaa ggagatgaac
     9001 taatgactta cacttcacta aaatctccag aaaagactga ctacctctat gacctaaaca
     9061 ttgctcatct ctacggaaac ctgatgaata cctacggtga caatgggaat gtcttgatgc
     9121 tcaagtatgt cgctgaaaaa cttggagcta gagttaccgt tgatattgtt tccctcaatg
     9181 atgcctttga ccaagattac tacgaccttg ttttttttgg tggtggacaa gactatgagc
     9241 aaaccatcgt tgctaaggat ttgcctagca aaaaagctgc tttagcggat tatatcgcta
     9301 agaataaagt ggtgcttgcc atctgtggtg gcttccaatt actagggcaa tactatgtcc
     9361 aagctaatgg ggttaaaatt gatggacttg gaattatggg acactacacc cttaatcagc
     9421 accaaaatcg ctttattgga gatattaaaa ttcataatga cgaatttaac gaaacctatt
     9481 atggctttga aaatcatcaa ggacgtacct tcttatctgg tgacgaaaag ccacttggac
     9541 gagtggttta tggcaacggt aataataaag aagaccaaac tgaaggtgtt cactataaaa
     9601 acgtctatgg tagttatttc cacggtccta tcttatcacg caatgttaat cttgcttacc
     9661 gcttagtaac aacagctctt aaaaaaaagt atggatcagc tatttcacta cctagctatg
     9721 atgatatact gaaacaagaa atcactgaag aatatgccga ccttaaaagc aaagcttcct
     9781 ttaataaagt ttaagttctt ctttcatgtc atcaaacaaa aactcctaag taggacacga
     9841 tagttcgctt aggagtttta tagttttttc ttctgacaga gcttcttaag tgattaaaac
     9901 cactaagaaa caatagcttt agcaacttct tcaacggtca tgcgtgagaa gtactgggtc
     9961 gtatcaatcg tttttaaacg ttcaaaaaca tcacggtact catatttaca accaattaat
    10021 aagttctcaa tgtcttgcac atctttgatt ccaaagaaat caccatagat tttaaggttt
    10081 ttaatgatag aattttcaac atttgcaaag gttgaaattt tacctgcagg gtaacgaaca
    10141 ttgcgttcaa tcgtatattc tggcgctttg ccgtaggtcc aatcccagct accaaattgc
    10201 tctttggcag attgttcaat cttagccaac tcatcctctg acaagacata ttctgtcatg
    10261 tctgggtacg tttctttcat cttggccaag attttatctg aaaattcctc aacggtaatt
    10321 ttttctggta attcatttaa aatattggtc acacgggcac gaacagactt cactccttta
    10381 gactcaatct tgtccttact taccttaaga gcatcgccaa gaacggtcat atccacatca
    10441 aacaaaaggc aaccatggtg catcatgcga cctttgtagt aagcttgagc attaccgcag
    10501 atttttttac catcaatttc aatatcatta cggcctgtaa agttggctgt tacacccaaa
    10561 tcagctaaag tcgcaatcac aggttgtgag aaggttttga aatcaaatgc gccttccgct
    10621 gttttatttg aaatgatagt gtagttcaag ttattcaaat catgataaac cgcaccacca
    10681 ccagataaac gtcgcacaac atgaatacca tgttcatcaa tgtattcttt attgatttct
    10741 tgaatggtat tttgatgttt gccaataata atagctggct cattgatcca aaggataaac
    10801 aattcgtctt cttccactag ttctctaaaa gcataggctt ccaaagcgat gttaaaggca
    10861 ggattgtgac ttttgttaac gatgtatttc ataggagaaa aaatcctttc aaaaatgtaa
    10921 tctacctctc tagtataatg aaaacaaata taaaagacaa gtgtcctatt ctgtatgaca
    10981 tcttcagtac ctacacttat tagtgcacaa aaactcagcc attatttatg taagggttta
    11041 taaaaatact ttaacgtggt atatttttac ttagtaaacc aatctacttt tattatctca
    11101 tttttatatt ggaggaattt atcagtgaat acttattttt gcacacacca taaacaatta
    11161 ctactttatt caaacctatt ccttagcttt gctatgatgg gccaaggaac tgccatttat
    11221 gccgatacac tgacttcaaa ttcagaacct aataatactt actttcaaac gcaaacgccc
    11281 actactacag atagcgaaaa aaaagtagta cagtcacaac aaaaagacta ctatactgaa
    11341 ttgttagacc aatggaacag tattatcgca ggcaacgatg cttatgataa aaccaatcct
    11401 gacatggtca cttttcataa taaagctgaa aaggatgctc aaaacattat taaaagctat
    11461 caagggcctg accacgaaaa tagaacttac ctttgggaac atgcaaagga ttattccgct
    11521 tctgctaata tcacgaaaac ttaccgcaat attgaaaaaa tagcaaaaca gatcactaat
    11581 cctgaatcat gctattatca agatagtaaa gctattgcta ttgtaaaaga cggtatggcc
    11641 ttcatgtatg aacacgctta taatctagat cgtgaaaatc atcaaacaac tggaaaagaa
    11701 aacaaagaaa attggtgggt ttatgaaatt ggaactcctc gtgctattaa taatacctta
    11761 tccttgatgt atccttattt tactcaagaa gaaattctta aatacacaac tccaatcgaa
    11821 aaatttgtgc ctgaccctac tcgttttagg gttcgcgctg ccaatttttc accttttgaa
    11881 gccaatagcg gaaatttaat tgatatggga cgtgttaaac tcatttccgg tattcttcgt
    11941 aaagatgatc tcgaaattag tgatacaatc aaagcaattg agaaagtttt cacgctagtt
    12001 gacgaaggaa atggttttta ccaagacggt tctttaattg atcacgtagt tactaacgct
    12061 caaagtccac tttataaaaa aggcattgct tacactggag cttacggtaa tgtgcttata
    12121 gatggcttat cgcaattaat tcctattatt caaaaaacaa agtctcctat agaagcggat
    12181 aaaatggcta ctatctatca ttggattaac cattcttttt tccctatcat cgttcgtgga
    12241 gaaatgatgg atatgactcg agggcgttct atcagtcgtt ttaatgctca atctcatgtt
    12301 gctggcattg aagcacttcg tgctatttta cgtattgctg acatgtctga agagcctcac
    12361 cgtttggcac ttaaaacacg tataaaaaca ctcgtcacac aagggaatgc tttttacaat
    12421 gtctatgata atttgaaaac ctatcacgat atcaaactta tgaaagaact actaagtgat
    12481 acttttgttc cagtccaaaa acttgatagt tacgtagcta gtttcaatag tatggataaa
    12541 ttggcactat ataataataa acacgatttt gcttttggcc tatcaatgtt ttcgaatcga
    12601 actcaaaatt atgaagctat gaataatgaa aatcttcatg gctggtttac ttctgatgga
    12661 atgttttacc tatacaataa cgatttagga cactacagtg aaaactattg ggcaacggta
    12721 aatccctacc gcttacctgg aaccacagaa actgagcaaa aaccactaga gggaactcct
    12781 gagaatatta aaacgaacta tcaacaagtt ggcatgacta gtctctctga tgacgctttt
    12841 gttgcaagta aaaaacttaa taacacaagt gctctagctg ctatgacctt cactaattgg
    12901 aataaaagcc tcactctcaa taaagggtgg tttatcttag gaaacaaaat aatctttgtt
    12961 ggtagcaata tcaaaaacca atcatctcac aaggcgtata caactattga acaacgaaaa
    13021 gaaaatcaaa agcaccctta ctgttcttat gttaacaatc aacccgttga cttgaataat
    13081 cagctagttg attttacaaa cactaaaagt attttccttg aaagtgatga tcccgctcaa
    13141 aatattggtt actacttctt caagccaaca acacttagca taagtaaggc acttcaaaca
    13201 gggaaatggc aaaacataaa agctgatgac aaatcaccag aagccatcaa agaagtttca
    13261 aataccttta tcactatcat gcaaaaccat actcaagatg gcgatcgtta tgcttatatg
    13321 atgcttccaa atatgactcg tcaagaattt gaaacctata ttagcaagct tgatatcgac
    13381 ttgttagaaa acaatgacaa actggccgct gtctacgatc atgatagtca acaaatgcac
    13441 gtcattcact atgaaaaaaa agcaacgacg ttttcaaatc atagtctttc tcatcaaggc
    13501 ttttatagtt ttcctcatcc tgtcaagcaa aatcagcaat aaaagcttgc tcatcaagga
    13561 attgcagcta aaaataatac tcttaactct cataaaattc cccacaaaag acaacgacgc
    13621 ttaccgcata ctgggtatca gtcctcctca ttagaattct taggtggagc tttagttgct
    13681 tcttttaacc atatcacaaa accctttcgt aagaaagact taaggattta gctgttattg
    13741 gaaagtaagg gttaacaatg aaacgttatt aaagacaaaa aaactggaaa ctgcactgag
    13801 ccccaaaagt tggctactct atttgaagta aaggatttag ttctgtgttg tagaggacta
    13861 agtccttttc gttttatttt gatacggtta ttggtgcaat aatcgatgat aataataggt
    13921 agaacgagtc aatttagccg tccttaaaag aaaatctaat cagaactcgt ctttatccat
    13981 tctttataat ggttttttgt cttcttcttt tcagagatgc ttctttcaaa cggagttctc
    14041 tcggtttttt tagcgctaaa tgtctagctt atcttcatag cttaatgtca tacaaaaaca
    14101 ccccaaacgt tagggtttta tatctaacgt ttggggtgca gttcatagtt gtgctagtct
    14161 tttttgtgat ctgttatgtg atgatatttt tcattagtta ataagacaaa gacgttttac
    14221 ttacgttttg gtgggttatg gatagcttcg ccaagcacat ctgcaaaggc ttcgtacatc
    14281 acttcagaga aagttgggtg tccatgaatt gataataaca attcatcaac ggttaattca
    14341 gattccataa tagtagctgc ttcgttaatc atctccgctg cagctggacc aataatatga
    14401 acacctaaga tttcgtggta tttggcatca gcaataactt tgacaaaacc atgggcttca
    14461 tttgaagcaa tcgcgcgtcc gttaccggta aagctatttt ttccgataag cacatcgcca
    14521 tattgctcac gcgcttgttc ttcagttaaa ccaaccattg ccacttcagg gtgtgtgtaa
    14581 acagccgctg gtgtgtattt aaggttagct ttacgagttg tgttgccatg catagcattt
    14641 tctgcagcca cttcacccat acggtaagca gcatgagcaa gcattttcgt tccgttaacg
    14701 tcacctggtg catagatacc tggaattgat gtctcttggt agtcattaac tttgatacgg
    14761 ttacgatcca tttcaaggtt aaggttttcc agaccgttca tttgtggtac acgaccgata
    14821 gaaagaagag ctttttcagc gacaacttct tcaccattgt taagtttcaa ggtcaattgg
    14881 ttatttgctt caacaatttc agagacacca acagatgttt tgatcttcat gcctttctta
    14941 gaaaggattt tttgaagttc aagagagact tccttatcca tagctgggat aatgcggtca
    15001 gccatttcaa taacggtaac atcaacaccg taagatgccc aaacaagtcc aagctcgata
    15061 ccaacaacac caccgcccat aactgctagt gattttggca tttcacgaag gtcaaggata
    15121 tcgtcagacg ttaagacaag tttagagtca attcctggga tattgatacg tgatacttta
    15181 gaacctgtag caaggataac gttgcgaccc ttaatggttt gtgacccaat ggttacagtc
    15241 ttatcagggt tgacttgacc aagcccatta aagatagtga ctttattagc ttttagaaga
    15301 ccttgaacac cacctgttaa ggttttaaca acggtgtttt taaagtcaac tgttttgtcc
    15361 atgtcaatgg tatagttagt tgaggcaagg ttaatcccac gtcctgctgc aatcttaata
    15421 ccatcaagga tttcagcatt tttaaggtaa gttttggttg ggatacaccc tacgttcaag
    15481 caagttccac caaattcaga tttctcaacg atggcaattt taccaccaag ttgagcacca
    15541 cgaatagctg cataataacc tgcagggcca ccaccaacaa cgatgatgtc atactcatca
    15601 tcagcaagtg cagcttttgg tgcagctgaa gcagcttgag ctggtgcttt tggcacttca
    15661 agtccagcag cttctaaatc ttctgttgta cgagcaacat tcacatctga agcagctggg
    15721 ctagaaacct caacagattc accttcagca ccgatatatc cgataacttc tgttacaggt
    15781 actgtttcac ctgcttgacg tgtaatttta agaagaacac ctgagtcttc tgcctcaagt
    15841 tccatattgg ttttatctga catgatttca agaagaatat cgccttcatt gacagtatca
    15901 ccttcttgtt ttttccactc gatgatttca ccttcttgca tgtcaacacc gagttttggc
    15961 ataataattt caacagccat aatttaagat accaagagca aggagaaagc gattgaattt
    16021 ttgcggtaag tcagaaatct ttgatttcgt tgacgcaccc acgtcaggac gactaggact
    16081 ttccgaaaca aaaattgagg aaagttcaga cgtctacgac gctaagatta gccaactctt
    16141 accattttta tccgagcttt tcgctcggat tcaattgctt atcactcatt tgcatgagag
    16201 ctcctcgttc tacatccttt ctatattttt gagaaaaggg caccaagtct aaacttagca
    16261 aaatcccttt tattattgaa tgcttttctt gtttaaaact gattgatcag attaacaatt
    16321 caaatggatt ttccatcaat ttcttgagat caaccatgaa ttttgcaccg ttcataccat
    16381 caactaaacg gtggtcgatg gttaggcaca tcgccataat tggacgggca acaatctcac
    16441 catccacaac cgttggagtt gggatagttg ctccaacacc aagaattgct gagtttggtt
    16501 ggttaataat tgggttaaat gtcttcgtac caaacattcc caagtttgtg atagagaagg
    16561 ttgatccaga catttcagct gccttcaact taccagtttg cgctttttta atcacatctt
    16621 ttgaagcaag cacaaaatct gacaagctca tcttgtcagc cccatggata acaggaacga
    16681 taagaccatc atcaagacct acggcaatac caaggttcac aaagcggtgc aattcaatat
    16741 cattagcatc attgatgagg gaagcattca tgtactcatg ctcaggtttc atcaaggttt
    16801 taaccactgc cataccaatc aagtctgtga agctgacttt aaggcctgtt ttagccatga
    16861 ttgggtcaat taacttctta cgaagggcaa tcatctctgt catgtcaata tcgtagttaa
    16921 gcgtaaaggt aggagcagta aggtaagagt ttgtcatacc tttagagatt gccttacgca
    16981 tagctgacat tggcttgtgt tccacacctt ctggaagatc aacaactttt tcttctttag
    17041 ctgctggggc ttttgcttca gctggtttag ccgcttcaag aatagccatg atatcttctt
    17101 tcatgacctt accgttaaag ccagtacctg atacggttgc caaatcaata cctttgtctg
    17161 ctgcaatttt acaagcaagt ggtgaagctt tcggttgagc acctttaaag ttttcaacat
    17221 cttctttatg gacacgtcct tttggtcctg ttcctggaac ttggccaagg tcaatgccca
    17281 tttctgctgc taccttacgt gcagctggag tagcacgaac ttttccgcca tttccttgcg
    17341 gaatagctgt cgctgccact tgaggagctg gacttgccac attttctttt ggagcaactg
    17401 ttggtccagc atctgctgaa gcaggaactg gaatttctgt tgttttttca cttgaagcaa
    17461 tagtatctac tgattcaccc tctgcaccaa tgtaaccgat aacttcagtt acaggtacag
    17521 tatcaccagc tggacggaca attttcaata gcacacctga gtcttctgcc tcaagttcca
    17581 tattggtttt gtctgacatg atttcaagaa ggatatcacc ttcattgacg gtatcacctt
    17641 cttgtttttt ccactcgatg atctcgcctt cttgcatgtc aacgcccagc tttggcataa
    17701 taatttcaaa tgccatttct acatcctttc acgatttgat aagcgccatc aacatcccca
    17761 ccttgctacg aaaacatacg aaaggtgagg tgccgcgaca cgggataaga caactcagtt
    17821 cttctaaaaa ctttcaaaat agtttttagc tgagacgtta ctgataaaca tagcctttat
    17881 cggaccactt gccttatctt ctagttgcct ttgtttgcca ttttcacaat agcagctttg
    17941 attttctcaa cgtctggtaa gatagcttgt tcaagtacac gtgcataagg tactggaaca
    18001 tcttcacttg caagacgaac gattggatga tcaaggtaat caaaggcttc actttcggta
    18061 atcatggttg caatttcccc aatgaatcca ccggtcttgt aggcatcgtt gacaagcatc
    18121 aatttacctg ttttcttaac agattcaata atcaactctt tatcaagtgg gatgagggta
    18181 cgtgggtcaa caacttcaac gttaatacca tccgctgcta cttcttcagc cgcttgaagg
    18241 acacgctcca acatacgacc atatgacaca attgtcaaat cagttccttc acgtttgatg
    18301 tcacctttgc caagtgggat atagaagtca ggatcttggt taacttcttc ttttttacca
    18361 taaagcgctt ttggttccat gaaaagaaca atgttattat cacggatagc tgattttaat
    18421 aagcctttag catcgttggc attaccagga gcaacaactt tgattcctgg aatgtgagtc
    18481 aaccatgctt caagagattg tgagtgttgc gcagcggaac caataccaga acctgatgcc
    18541 acacggaagg ttacaggggt aataaggcct ccaccgaaca tgtaattatt tttagcacca
    18601 ttattcacga tagcgtccat catgatggta aggaaatcca tgaaggtaac gtcgacaatt
    18661 ggacgtagtc ctgtaatcgc tgcaccaata gccgcaccag agatagcagc ttctgaaatt
    18721 ggggtatctt taacacgttt aggaccaaat tcttcaatca ttccaacaga agtcccgaag
    18781 tctcctccgt aaacccctac gtcttctccc ataaggaaaa tgttttcgtc cttgcgcatt
    18841 tcctcagtca tagcaaggtt gactgcttca cgcaaagcca ttaattttgt ttctgacatc
    18901 atttttactt ctccatttat tattcaaata cgattgcttc ttactgacaa ggtgatctta
    18961 gtcaacccaa acgtcttcga aggctactga aagttctgga tctggactgt tttgtgcaaa
    19021 ttcataagca tcgtcaactt cttttttgac ttgtgcttga atagcatcca attcgtcatc
    19081 agtggcaatg ccttcgcttg tcagataagt acgatatttg atcattggat ctttttcttt
    19141 ccactcatcc acttcttctt tagtacggta tttaccagca tctgcagtcg agtgaccaaa
    19201 ccaacggtat gattctacct caacaatagc tggaccattt ccaccacgaa catgttcaac
    19261 ggctttgccc attgtttcat agacagccat cacgtcattg ccatcttcac agtagaaacc
    19321 aggaattccg taagcttctg cacgtgtgta taaatgtggt gtatttgttg cattattgat
    19381 gctcattgaa attccataac ggttgttgat gatgaagaaa ataacaggaa gtttccatgt
    19441 tgcagccata ttaacagact cgtggaatga tccttcgtta gtagcgccat cacctgagaa
    19501 agcaacagct atattgttag ttcctttgta ttgttgagtg agggcagcac caactgcaag
    19561 agcgtaacca ccaccaacga taccattggt accatagttt cctttttcaa aatcagccaa
    19621 gtgcattgag ccaccacgcc ctttagaaac accagttgct ttaccagcaa gctcagccat
    19681 cattttatta aggtccatgt ctttagcgat tgattgtcca tgtccacggt ggtttgaaaa
    19741 aataatgtca tcgtaagaca agtgagccac cgctccaaca ttggctgctt cttcaccaac
    19801 tgagaagtga gtcatccctt gtacaaatcc acgacggacg agtttattaa tacgtgaatc
    19861 aaattcacga atacgttcca ttttaaggaa catatctaaa tgttgttctt tagaaactgt
    19921 taccatttcg gcctccatat tatcatatta cttttttatg ataaaacttt ttttcacaat
    19981 ttgcaaataa ttaaatcgct ttctacctta ccttatttgg ttttttagaa atgcaatagt
    20041 ttgtgaaatt acaaacaaaa ctgtactaaa aaatttaaaa atactatata acagtttcac
    20101 gttttaccga ccttgacata aaaaacacat cattttaaaa cctctttcac accttcaaac
    20161 aagtagcaaa gcgataaaaa taagcttagc aaaactgcta aagcttattt ttatgattct
    20221 atttgttcag cgatggtttc ccattcttcc ataagagctt cttgttcttg atccaattgg
    20281 tcccattcct tttgccaagc gattaactgc gccgtatcat tggaggcatg catgtcttct
    20341 tgaatagcac caatacgctc ttcaatggtt tcaagtcttg cttcaatctc ctcatatcgg
    20401 cgggtcaagc gacgacgctc tttttgatta gctttttgta gctgataatc agtggcagag
    20461 gcttcttttg tttcctcaac tgtctctcct gctgctaggc gggctaattc ttctagctct
    20521 gcctttttct caaggtaata atcatagtca cctaagtaaa gggttgagcc attttcggta
    20581 atttccaaaa ccttagttgc caaacgatta atgaaatagc ggtcgtggct gacaaaaagc
    20641 aaggtaccgt caaagtcaat gagggcattc tctagcactt ctttactgtc aatgtctagg
    20701 tggttagtcg gctcgtccag aacaagaaaa ttattgtttt ccatagataa cttcgcaaga
    20761 agcagacggg ctttttctcc acctgacagc atagccaccg attttttgac atcatctcca
    20821 gaaaagagaa aagcccctaa tcggtttctg atatcgactt ctggcgtagt tgaaaaatcc
    20881 tgccataatt cttccaaaac tgtgttgcta gacgtcaaat gtgattgggt ttggtcatag
    20941 taacctattt caacattggc accgtatttc acttctcctt tgatgaaagg aatctgtcca
    21001 ataacagatt taatcagagt ggatttacca ataccatttg gaccaacaat agcaatcgca
    21061 tctaatttgt gaacgtctag gttaataggt tcagataaga catgttggtt ataaccaata
    21121 gcagcttttt caaccgtcaa caccacattg ccagacggct tatctgcctg aaaagtcatg
    21181 tgagctgatt ttctagcact agtcggtttg tctaagcgtt ctattttttc caattgctta
    21241 cgtctcgcct gagcacgttt tgtagttgaa gccctgacaa tatttttttg aacaaaatct
    21301 tctaacttgg caatttcttt ttgctgtttg tcaaactgct tttcttcggc tactaatttt
    21361 tcagctttta aggtcataaa acgagaataa ttgccaacgt agcgatccaa tccatgagga
    21421 gttaaatcca aggtcactgt tgccacctta tccaaaaaat aacggtcgtg actcacaatg
    21481 attagagctc cttgataatt ggccaagtag ttctctaacc aggcaatggt ttcaatatct
    21541 aagtggtttg ttggctcatc aaggaccaat agttctggct tttctaaaag cattttagcc
    21601 aaggccagac gagtattttg accccctgac agctcagcga tagtcatctg ccacatgctc
    21661 tcatcaaact taaacccatt taaaatggct ttgatgtcag attcatacgt aaagccgcct
    21721 tgctgacgaa aatgctctgt aagcagatca taatctgtca tcagtcgggt taaatcttga
    21781 cctgaaacgg ttgccatatc catttccatc tgacgcaggc gcttttcatc ttggcgtaat
    21841 gcttcgaaaa ccttgagcat ttcctcatat attgtttgat ctgattcaaa acggctattt
    21901 tgagccagat aagacaaggt taggtctttt ttagtattaa cttctccgct cgttggggtt
    21961 tcttccccaa ccaatagctt gagtaaggtt gacttaccag ctccatttgg ccctactaat
    22021 gcaattctgt ctctttcatc aacttgcagt gatatatttt gaaaaagaac atctcctgag
    22081 aaagagcgtt ctaacttgtt tccttgtaaa ataatcatac tttcattcta acaaaaaaat
    22141 gcccttttga ggacattttc agcctagttt ccaaaagaaa tcgaactctt tttaagtcgt
    22201 tgattacctt ctttagcgct aacaaggaaa gtggaatgac tattaccact cccatgacgc
    22261 gtctttgcag atggcttttg tgttaagata tcaaaaattt gcaccacttg ctcagtaact
    22321 atcgagatct tattggctaa aacggaatca ctgtgattag aataatacat cagccctata
    22381 ataataatcg ttactaataa gatagtttgt aaaaaccctt tgataagatg ccaaaacagt
    22441 ttcactatta gcttaggaag ccacaaaatg atcgccagta attgtttcat tcgtcacctc
    22501 atgttgtact aggaaatggt taagataacc tttcttcttt ttggtagttt atcggtaacc
    22561 actctaacag aacttctaat tgttggttcc aatagtacca ctcatgttta ccatgacctt
    22621 tatgatagtc aatgtcaaga ccttgagctc gaaaatcagc aatagctttt tcattagcgg
    22681 caaaaaggaa atcctcataa ccacaccaag cataaaattt ggtttttcca tcactttctg
    22741 ccaccatatt tttaaggtaa tgcttatcaa ggtcagggtc atcaaactgg ccaaaaacgc
    22801 cctgccaata ggctaattct cccaggtttc cctcaagcaa ggtcttagga gaaaaatcca
    22861 aagcgcctga aaacgatgcc gcataagaaa accgattgct tttgagtgcc cacttaaagg
    22921 caccatagcc acccatagag agcccagcaa caaaggtttt ttctcgtttc tgggtcatat
    22981 taggaaagaa agctgctaag acctgcggta actcttgtga caacgcccga taatagttaa
    23041 gtccataagc cgtgtctgta taccaaccta ggtctgtcga aggcataacg actatcaaat
    23101 tggtatgccg caacaagcgt tcaatagctg ttcgtttttg ccaagagttt tcattgcctc
    23161 ccataccatg taacaaatat aaaacaggaa tatccttatc cccttgatct tttttaggga
    23221 tttcagactg gtcaggataa atcacattta ccttacgctc cattcctaaa actaccgaat
    23281 ggtattcaat tgcaatattt gccattcatt acactccttt ataccaaaat aatcctatca
    23341 cgtaaatcta ctgtatttgt gggtgaacag tttcctggtc taccagttgt taaaatcaaa
    23401 gaaggtaggc agtttttgcc taaccttcct attttcacta acgaacttcc attacaaccg
    23461 gcagaatcgc tgggcgcctt ttggtttgtt caaataagaa tttagacaaa tcatctctga
    23521 cattcccttt taattcgccc cagtcaaagg tatctttttt taagtaattg ccaacagttg
    23581 tattaactaa ttctgcactt tctcttaaaa tatcatgact tttcttgaca tacacaaacc
    23641 cacgcgtatt aactttagcc ttagaaataa tgcgtttttc ttttttagaa acagtaatag
    23701 caacaatgaa aataccatct tctgacaaga ctttacggtc tcgtaaaacg atattaccca
    23761 catcaccgat agcattaccg tcaatcatga catcactggc aggtacacct ccttcatgga
    23821 gaaaaccttc gtcattaagc accatgatat cgccacgctt cagaatatga atattctctg
    23881 gaaaaatacc aacttcttca gctagctttg catgggcagc taaatcacga tattctcctt
    23941 gtactggaaa aagatattgg ggttttaaca aattcatcaa tagttgcaaa tcacgcccat
    24001 tagcatggcc tgaaacgcgt aagttttgag tgattaattt aacagaacca ccggccttgt
    24061 aaatcaagtt ttcaacacgc gccaccatag cttctttagc cgtacttggt gttgttacaa
    24121 tataaacaag gtctccttct ttgatttgaa cataacggtg acgtcccgct gccatttttt
    24181 gtaagctatt aattggctca cccatacgac cagcttcaag gatgattaat tcatggtctt
    24241 cgaatttaga catatcctta ggtttaatta aaagacgctc atccgtaatc attaattttt
    24301 ctagacgtaa agctgttctg acaatgtttt ctgcatctgt tccggttaaa acaacacgac
    24361 gcccatgggc agtggcggaa tcaaatactt gttgaatccg aacaagattt gaggctactg
    24421 cagctacaat gacacggcca tcagcatcag agataacact gtccatttct tcaccaactt
    24481 cagattcgct agcaatctga tcgttgcttg tcgcattgac tgaatctgat aaaagagcta
    24541 gaaccccttc tttcccaatc tcagctaaac gtagcaaatc cgtctgataa ccttctcttg
    24601 ctgcttgatc aaatttgaag tcaccggtat aaacaatgtt tcctttatct gttccaataa
    24661 caatacccat actttctggg attgaatgcg ttgttctaaa gaacgaaact aggccatctt
    24721 taaattcaat ttcagtatca ctgtctacca catgaaaatt attaaatttc ttagtgctgt
    24781 tattactttt cacaaatagc ttggctaatt caatagtcaa ttcagatcca aatacaggag
    24841 ctgatacttc agctaacaaa taaggaagag ctccaatggc gtcagcatgg ccatgactca
    24901 agaaaatccc ttgtacctta tctttgtttt caattacata atctaaattg gggatgacta
    24961 aatctacccc aagttgctca ttttcggggt acttgagccc tgcgtctaaa ataaacatag
    25021 aatcgttaat ttctaccaaa tagaagtttt ttccgtattc acggacccct cccaaggcaa
    25081 tcattttaat atcagtcatg atactccttt aaatatttta ttattacaaa cggtccttac
    25141 aacgtaagtc gaattactgt tatgtagcta tgctactatc ttctatagta tatcatattt
    25201 gaggcgtttt ttctctaaat agccttgata ctttcagatt attttcagta cagaaatcaa
    25261 aaaatcactg tcttattatt agtcaatgat ttagatcgtt gactaatcaa atagttggta
    25321 atagtcagta atcgtcagtt gttctttttc catttgattt aaatctttaa taatgtttcc
    25381 atctttcatt acaatcagac gattcccata agttaatgca tcttccatat ggtgggtaat
    25441 catcaaagct gttaagccat cttttgtcac aaactcatct gtcaattgca ttaaagattg
    25501 actcgtctta gggtcaaggg cagccgtatg ttcatctaat aataagagag ctggcttttt
    25561 caacgttgcc attaataaac ttaaagcctg tctttgtcca ccagacaaaa gacctgctgg
    25621 tgtttctaaa tgcttttcta ggccatttcc tgttcgttta accaaatcct caaaactagc
    25681 taagtgctct gttatttttc gagaagccaa ggagcgtttt tctcctcttt gacgtgcgat
    25741 taagagattt tcagccactg tcatccgagg ggctgttccc attttgggat cttgaaagac
    25801 tcgcgatagg taaagagctc ttttttctgc aggccaatgc gtcacatcct gaccaagaat
    25861 cctaatttgt ccccgtgtca aacttagcgt tcctgcaatt acattaaaaa gggttgattt
    25921 tccagctcca tttcctccta aaatagttaa aaaatcatgt tcatagatag ttagtgtcac
    25981 attgtccaat attgttttag catcttcaaa accattatct acgtcaactg ttgcattgat
    26041 caattcaata atttttgtca tcgtgttaac ctcactccct taaagaagcg ctcttttacc
    26101 actggtatca tgaggcacag tgctaaaaca agagcactaa ttaattttaa ataacttgta
    26161 ttaaaaccta gcgtaataac tactgaaatt aaaaattgat aaagaatcga gcctattaca
    26221 atagcaatca aacgttctaa aagagtcagt ccagttgagt atagtacttc accaacaatt
    26281 atgctcgcca aaccaataac aataactcca atcccttttg agacatctgc atagccatct
    26341 tgttgactca ctagagcacc tgataaagct attaaactat tagaaaccac aagtcccata
    26401 acttccatcc aatccgtgtt aataccaaaa ctcttagcca tatctttatt gtctcccgta
    26461 gcgatataag cttgacctag attagtgtaa aggaaataga tcaaaacgct aataacaatc
    26521 acaacagtta tcagacctgt taaaaggcta tttaaatcaa ttgaaaaagg taaacaatcc
    26581 tgaatacgtt tatgatcatg taaacccaag tttgctcttc ccattaccat tagcataatg
    26641 gagttacatg acgtcatcac caaaattcca gctaaaagtg ttggcatttt tcctttcgta
    26701 tataacagcc ctgttagaaa acctgctaaa gcacctgata acataccaag taaggttgat
    26761 agaaatggat tccaccctaa gctaatagcg gtgaccgcaa cagctcctcc taaaggaaaa
    26821 gaaccttctg tagtcatgtc agggaagttt aaaatcctaa aggtcaggta gattcctaat
    26881 cctaaaactc cccatataag gccttgtgaa actgatgaaa taatcatatt tttcctcata
    26941 tttatattag cgggtaactc tcgccagtat aaaccctttc tttacattaa tttttagatt
    27001 tgttttgtac ttagttcagc accgtggctt agtctttttt tcaatcactt tgacgaaact
    27061 aagacagaaa acaaaaaagt cgagaatcat gtttaaactt actcaaaagg caagattttt
    27121 tacgtgtcta aaatagagca ttttaaaact aaaaatgata aaaataaccc ttacatcctc
    27181 aagacgattg tctgacttgg catccaaatt catctcagtg agggtgtttt ttatggtttt
    27241 ttcttgacct tttatatcac atgtcattgt attaattctc aataaaagaa gctgaaggaa
    27301 aatcttccct tttaatagca atacctaatt ctgctgctac attcttatta attagcggtt
    27361 gaccaatatc cacaactttg acaggaacat ctacaacacg ctttcctttg attaatttta
    27421 acacctgatt agctgtttga actcccaaat cgtactgatt ttgagaaata gctgccaaac
    27481 cacctttttc aaccattcga tcaacgctag tgtagacagg aatctttgca gccttactgg
    27541 ttgtcatgac tgatgaaaat gcacttgcta tagtattgtc ttgggggata aataccgcgt
    27601 ctactttacc taacataact gacatcgtgg caggaacttc gttagtagaa ggaaccgcgt
    27661 atgaaataac ttgatagccc tttttgcgag ctaaccgcct aaactcttta acttgagata
    27721 aggaattatc ctcattactt gcatataaaa ttccaactgt tttgacatgt ggtgtcagct
    27781 ttttcattaa atcaattgtc tgtttaacag gcactttatt agatagacca gttacattag
    27841 cttcaggttg atccaattgc atcactaatc tagatcctac tggatcagat actgctgaca
    27901 tgacaactgg gatatccttg ctggcagctg ctaagccttg cgccgccggg gttgcgatac
    27961 caatcacgat atcacttcct gattgcacta attgcctact cattgtttgg attttactct
    28021 gatccccctc agcattcata accttaatca ctacattttg tttttgaggc atctgctttt
    28081 tgagttgatc ttcaatacct cgcttaatat catcaagagc ctcatgagta acgaattgta
    28141 agataccaat tgtaatgttt tgtcggttag ccaaatcacg gttttccttt gatactcctt
    28201 ttgataatag agagcctatc actattacag ttaaaacaag gagggtagct attaaactct
    28261 tgtttttcat ctgaattcct cacatttcat gtcaatctct ttaaaacgtt gatgatgaga
    28321 atacttctca aaagaaaaag cacttagtaa tgattactag gcgctcttgt gaaatccaat
    28381 gtcagcgcat agatatcttt ttagaagtac tctaaaagtc gtatctatgc caattcataa
    28441 acacaactta tctatgccag ctttgccaat ttactaagtg ttgtgttttt accatcattg
    28501 acttcctttc tcgttttttt aacattataa cctaaatcaa aaaaattgca agctctttcg
    28561 tccatatttt tagtcaagta tttgtggtat aatgaagaga ttagaattca gaaaggagaa
    28621 accatgtctt ttgacggctt tttcttacac catttaacca acgaattaaa agagaacttg
    28681 ctttacggtc gtatccaaaa ggtcaatcaa ccctttgaac gggaacttgt cttaaccatt
    28741 cgtaaccatc gcaagaatta taaattgcta ttgtctgccc atcctgtttt tggaagggta
    28801 caaatcaccc aagcagactt tcaaaatcct caggtaccta atacctttac catgattatg
    28861 cgtaaatacc tccagggtgc agtcattgag cagttagaac agattgataa tgaccgcatt
    28921 atcgaaatca aggtatctaa taaaaatgaa atcggagatg ctattcaggc aaccctaatc
    28981 attgaaatca tggggaagca cagcaatatc atcttggtgg accgtgcaga aaataaaatc
    29041 atcgaatcca ttaaacatgt tggcttttca caaaactctt accgcaccat tttacctggc
    29101 tctacctaca ttgagccccc taaaacagct gctgttaatc cttttacaat tacagatgtt
    29161 cctctatttg aaatcctcca aacacaagaa ctaacagtta aaagcttgca acagcatttt
    29221 caaggtttgg ggcgagacac cgcaaaagag ttggccgagc ttctgaccac agacaaatta
    29281 aaacggttcc gtgagttttt tgctagacct actcaggcaa atctgaccac agcttctttt
    29341 gcgcctgttc ttttctcaga tagccatgcg acgtttgaga ctttatcaga gatgcttgat
    29401 cacttttatc aagataaggc tgagcgtgac cgtatcaatc agcaagccag tgatttgatt
    29461 caccgtgtgc aaactgaact ggacaaaaat cgcaacaagc taagtaagca agaagctgag
    29521 ctgctagcca ctgaaaatgc tgaattattc cgtcaaaaag gagaattatt gaccacctac
    29581 ctcagtctgg tcccaaacaa ccaagactct gtgattttag acaattatta tacaggggaa
    29641 aaaattgaga ttgccttaga caaggctctg acaccaaatc aaaatgctca acgttatttt
    29701 aaaaaatacc aaaagctaaa agaagctgtc aaacacttat ctggattgat tgccgatacc
    29761 aagcaaagta ttacttactt tgagagcgta gactacaatt tatctcaagc aagtatcgac
    29821 gatatcgaag atattcgcga agaattatat caggctggct ttttgaaaag tcgccaaaga
    29881 gacaaacgcc ataaacgtaa aaagcctgag cagtacctgg cttcagatgg aaaaaccatt
    29941 ctcatggtgg gacgcaataa cttgcaaaat gaagaactca cctttaaaat ggctaaaaaa
    30001 ggagaactct ggttccatgc taaggatatc cctggaagtc atgtcatcat caaagacaat
    30061 cttgacccaa gtgacgaggt taaaactgat gctgccgaac tagctgctta ttattcgaaa
    30121 gctaggttat caaatctcgt tcaggtcgat atgattgaag ctaaaaaatt acacaaacct
    30181 agtggcgcca agccaggatt tgtgacttat actggtcaaa aaaccttacg ggttactcct
    30241 gaccaagcca aaattctctc tatgaaatta tcctgataag caactaaaaa acagctctcc
    30301 taggaaagtt atttccccta ggagaactgt ttttttattc tgattgttgg tgcttgatat
    30361 ggtcaagaaa gtcttgcata ttcacatcat caggcacttg tctgaggtaa gcggtagcca
    30421 tttggatagc cttgtgaaac tggccaaact cccttaataa ataggcataa tcctgtaaaa
    30481 actctggatt ttctgccaaa tcagccgaaa tctcattata aagagccaaa gcaacttctt
    30541 cttgttccaa ggcgtggtaa gcctttgcaa tggtccattt ggttaagaca ttatcaatcg
    30601 tctcacgatt aagagcaata acctcctcaa aacgctcagc atcaaaataa agggtcacta
    30661 aacgcatgag aatctcttcg tcatcaacag ctacttcctt tgcttgaagc aggtaatttt
    30721 cagcattctg cctatcgtgt aattcataag aaagctgcga tgctagtaat aataattgac
    30781 tgtcaaatgc atttttacgt aggccctgtt gaaccaagcg caaagcttct gacgtcttat
    30841 gctcttcatg aagactcaaa gcataaccat attcataacc tggataatct ggattgatgg
    30901 tttccaactg tttaaagtaa agattggctt tttgataatt ttcttggtca tacatgaggg
    30961 tcgccaattc aaaaacagtt tcatcttcgt attcaatggc cacggccttt tccaagaatt
    31021 cgatggctgc ctcaaatttc cctaagctag cataggctcg tccaatgcgt tgataagtgg
    31081 aaatacctgt caattcaagg atttgacgat tgtctaactg tgcatagtaa tcaatagctt
    31141 ctttaaaata ctgcaaggac atgtcgattt ctgccaaacc aaaaatgacc aatggctctg
    31201 agctgatggc cactgcttga agcaattttt cacgcgccac ctctgtcagt ccttccaggt
    31261 catagaggtc agccatgact aagagagctg acaaataatt agggctatct tttgaaacct
    31321 tatccaaata caagaaagct tcttcaatgg cgtcgtcttc tgctgcaatc tgagctaaat
    31381 ttatattgag ttctgggtaa tcatcagcta actgcaaata aatacgcttg gcatgtggca
    31441 aaaaacctat actttctaag tattctccta aggcgattaa actatctgca tcatcttctt
    31501 ttaaagcttt ttggaaatat ttttcagcgt gcgctaggtc ttgctgatcc aaggaagcaa
    31561 tcattttttc actatttaac atggtcctta acctcctcga tcaccaatac ttcttcgtca
    31621 tacaaaccgc taactttttt gtaccagtca aataattctt taatcacgac tttgacagaa
    31681 gcgtagattg ggatgacaag gaaaacaccc cagacaccaa acatagagcc tgcagtcaat
    31741 aacaagaaca taatggtaat aggatgaatg ctcagcttat ttcccaaaac aagcggtgct
    31801 acaaaacgcc cttcgatggt ttgctcaatc ataaagataa caagcacctt aaccaacata
    31861 aatgggcctt gtaccatagc cataatcaca acaggtatca tggcaaggaa acttcctaag
    31921 taaggtatca tgttaagaaa gccagcaata atcccaaaag tgatggcata tttcagtcct
    31981 acgaggctaa acatgataga aaacataaag ccgacaacaa ttgcaaccgt aacctgccct
    32041 tggacatagc ctgataattg cttgttaata tctcccaaga ctcgaaccat aggcacccgt
    32101 aatttgagag gtaagacatt cacaaggcca tttttcatgt gactactgtc tcgtaaaaaa
    32161 taaaagagaa taaagggcga aataataata gccacggtaa tccgagcaat ggcaccagca
    32221 aaattaccag cccagtcaat agcatttttt gaaaaacttt gcgcgtaatc caaagccttt
    32281 tgacttgtat gggtaagcat gtcttggagt tggggcttgt agctgactaa ccattcattt
    32341 tcaagaagtt tattggcttc ttcattgacc ttgcccacgt atttgggcag atcctcaata
    32401 aaactggtaa gttgggtctg taccatggga acaaagcctg aaatcgccca gacaaaaagt
    32461 aaggtaatca aaccaaaaac aataaaaata gaggtggtac gattcgggcc caagcgatta
    32521 ataaggtcaa ctaagggttt ggtcagataa tacagaatgg tcgaaataac caagggcaac
    32581 atgatgaccg caaaaaaaga aatcactggc ataaataaaa aagagatttt agtaaaaaca
    32641 aaaatcgtta aaaaggctaa aagtgttatt actaaagcca tggtagcttg attatttaaa
    32701 aaccatttgt aaaataagct atctgttcta gacttgtcag gtattaaggg cattaagata
    32761 gggttccttt ctttgggaaa atgataagtt ttactggtaa cctgggtaaa tcaataaaag
    32821 gtcacagatt tatccatgag ttggttgttt tggtcatagg taaatttggc agagaaaaaa
    32881 ggacggtctt ctaaaatcca tttaaaaatg tcataatcac cttcccaagt tggcttttcc
    32941 aacacttgat cgtaaggtac ccattccaag gttccttctc gtgactcttc atctgaaatg
    33001 aggtctcctt caaatcctgt tactttaaaa acataggtat accagtcatg accaggggta
    33061 aattctggaa aagtaatgat tcctttaaag gccatctctg taacagtcaa atgggtttcc
    33121 tctaaaatct cacgacgggc acactcatct ggggtctcac cagcctcgag cttaccccca
    33181 actgaaatcc acttgccttt gtggacatca ttttcttttt tattgcggtg taataatagc
    33241 aaagaatcgc cattatcaat gtaacaaatg gttgctaatt gagtcatcta tctctttcct
    33301 ttccatcttt gtttctatta taccaatctc tagaaaatat gctatcattt tatgagtcaa
    33361 agtgtgaata cttagtcacg ctcaaaacct tctaaagatg ccttaaaaaa gtgtagataa
    33421 gagcctacaa tgaaaaacat caatttaaac tatcaaaaga accttgtcat atcaacgata
    33481 attgatatga caaggttctt taatgtttta tttaatcact tcttgagttt tagcatactt
    33541 agcttctaca gcatcttttt ctgctttcca ccatgtctca ttttctgtgt accacttaat
    33601 agtttcttcc aaaccttctg aaaagtttgt aaattgtggt tcccagccga gttcttcacg
    33661 caattttgta gaatcaatag cgtaacgaag atcgtgacca gcacggtcag ttacgtgatc
    33721 ataagcatct tttggttgac ccattttctc aaggataagc tcaagaactt ccttgttatt
    33781 tttctcgccg tcggcaccaa taaggtatgt ttcaccgata cgacccttag tcaaaatagc
    33841 ccagacacct gttgaatggt catttgtgtg gatccagtca cggacgtttt taccttcacc
    33901 ataaagtttt ggtttgattc ctgccaagat atttgtaatt tgacgtggaa tgaatttttc
    33961 gatgtgttgg tatggtccat agttatttga acagttcgaa atggtcgctt tcacaccgaa
    34021 ggaacgtacc catgccttaa cgataaggtc agaagctgcc ttagttgatg agtaaggtga
    34081 tgatggattg tattttgttt cagcagtgaa tttttcacct ggtccttcac cctgtcctgg
    34141 aaggtcttca cgaagtggaa gatctccata aacttcatca gttgacacgt ggtggaaacg
    34201 gatatcgtat ttacgagctg cttcaagcaa agtgtaagtt ccgataaagt ttgtatggat
    34261 aaatggactt ggatcttcca atgagttatc gttgtggctc tcagccgcat agtgaacaat
    34321 agcatccgtt ttggcagcca atttgtctac caattcagcg tcagcgatat caccaacaac
    34381 taactcaaca cgatcaccaa gaatagcttc aatgttagca cggttacctg catatgtcaa
    34441 tttatcaagg acagttacat gaacatctgg gtggttattg tagacatagt gtacaaagtt
    34501 agaaccgatg aaaccagctc caccagtcac gataatattt ttatacataa gatataaagg
    34561 gacctttcgt ttccgaaaaa atctattaaa agtaataact ctaacaaaga cgttttaggc
    34621 ctaagaaaac atcgctttct aagatttgag tcccatgttc agctcaaaga gagaaactga
    34681 actttccttt catcattttt agttgttact tgttacctga agtagagaag aataactccc
    34741 ctcatatcca cctcaaatga ttaatcccaa tcatctgagt atgttgtttc cctataggtc
    34801 ttttggtttc agtggtttga catcactaag aagaggatgg tttttatctg cttcagaaac
    34861 ttctgcagct gctagatttt cccaagtaat cccaagactt gggtcagcat agtttaccaa
    34921 agcatactta ggtttcaagt caagagccca gtagtcattg acaagataac tgtaagagac
    34981 agtctctgaa agaacttgaa agccattagc aacccctcta ggaacaaaca ttccttttga
    35041 agcatcaatc actgtctggt agacgtttcc aaaagtctct ccctcacgaa gatcaaccca
    35101 agctcctaaa accttgccat catcagcaac tgagatgtat ttatcccaag gttcagcatg
    35161 aagtccacgc agcacatgct gacgtgaaaa agaaacgttg ttttgtagtt ttccttcctc
    35221 aaaaaaacgt tctggaaagc caattggcaa cattttttct ttttggaaat tttctttaaa
    35281 ccagccacga ttatccccac gaacaggaat atcaaactct agtaagcctg ggatttcttt
    35341 gatttctcgg caagccaatg gtttgtcaaa aaaagtttct gtcattaagc ttctccaatc
    35401 aaacgaagca agtattgccc gtattcgttt ttctttaaag attgcgccaa tttatggaca
    35461 tcttctttac tgatgtaacc catgcgatag gcaatttctt ccagatttgc cacttgagcg
    35521 ttttgcaaac gttgaacagt ttcaatatat tgagccgctt caagtagact ttcatgcgtt
    35581 ccagtgtcta gccatgcaaa accacgcccc atcaattcaa cggagaggtc accacgatcc
    35641 aagtaagcct tgttgacgtc tgtaatttcc aactcaccac gcgcgcttgg tttaatgttt
    35701 ttagcaatct ctaccacgtc attgtcatag aaataaagtc cagtcactgc aaagtgggac
    35761 ttaggcactt ctggtttttc ttcgatagag atagcattca tgttctcatc aaattccacc
    35821 actccaaagc gctcagggtc tttcacttga taaccaaaaa cggtggctcc tttttctttg
    35881 gcagctgcct tttgaagcat tttagtgagg ccattaccgt ggtaaatatt atctcctaaa
    35941 ataagagcaa cacggtcatc accgataaac tcctctccaa taatgaaagc ttgtgctaaa
    36001 ccatctgggc ttggttgttc cttataggat aagctaatgc caaactctga cccatctcct
    36061 agtaattctt cgaaacgagg aagatcttgg ggggttgaaa tgattaaaat atctttaatc
    36121 cctgccaaca tcaaggttga caatgggtaa taaatcattg gtttgtcata aatgggcatc
    36181 aactgtttag atgcggcacg ggtcagtgga tacaagcgtg tccctgaacc tcctgcaaga
    36241 ataatacctt tcatagtagt gctcctattc ttctatatac cctatcattc tatcattttt
    36301 tgaaagcagt gtcacgcttt accagcagac cacaaaaggt aaggctcagg ggaatagtcg
    36361 ctaggcgtta aaagtccttc gtgtcctagc aataattgag ctaattcata gccaatcaaa
    36421 ggtccaactg ttaatcccga tgaccctaaa ccactagctg tataaaggtt cttcaatcct
    36481 ggaacctgac cataaaaagg agaataatca ctggtataag ctcttattcc tacacgacac
    36541 gttttttggg tagcttcttt taataacggc aaataagtaa gagcttgcat ttcaagtttt
    36601 tctaaaacct gccaatcagg ctccaaatca taacctttat cattttcgtg actcgcacca
    36661 acagaaatct taccttggtt aaaaggaata agatctattt caccttctgg cataacaact
    36721 ggataagtgt cgctgatgat gtgatgaacg tcataatcca agagttgtcc cttttgtggt
    36781 cgcacatcaa cctgatagcc taaaggcctc aataagtcag gtagccatgc tcctgctgcc
    36841 agaatgacct gatcaaaata atgaccagca atctcatacc cacttccttg ctgtttcaga
    36901 gtgacttttt ggcgaataac tggataacca ctggccttga gtaacgtctc acataaagcg
    36961 gctccctcca ctctagcagc tcctgaagcg tacagacagt tatcaaagcc tatcaatcct
    37021 ttaaaatcat tccccagttc tttacgattt ttaatggcta actcaccaat aatcggtgat
    37081 tctacctttc ttgctaacgc taattcataa agatctctta gtttttcttc ctgctttttt
    37141 aaaacataga tgccattttg ctgataaaaa tctgttgcaa aaccatcttc tttgaggtca
    37201 ttgattaatt gctgataaaa gtccgctcct aaacgagcca tgcgatacca aactttattg
    37261 cgacgctttg aaaaccaagg actaataata ccagcagcag ccttagtggc ttgtccttga
    37321 ccatggtcaa aaatggtaac ttctttttga ccactttgtt gtaaataata agcggcggtt
    37381 gatcctacaa tccccgctcc aacaattgct attttcattc ctggtatcct tttatcttat
    37441 tttaagacct taacagccta taaatggcta aatggattgg tcgaggcttt gcttgaaata
    37501 atgctgacat cccaaccgtt ctcttctttc cacccttgga gtttctcctt taatttctcc
    37561 gtaaaaagca cctcaatatg atgccccggg tcaaccgcaa atagtccttc tgtcagcatc
    37621 tcctgtgctg tatggtaata gatatcccct gtaatataaa cgtctgcgcc tttttgcaca
    37681 gcatcctgat aaaattcacc accacttccg ccacagatag caatctttga aatcaaaggg
    37741 ttttccttat cgtaacggat aagtcgcacg gtatctaaat caaacaccct tttgacctta
    37801 cttgctaact cttctaacgc ttgttcttta actgttccaa tacgaccaat gccaaagcct
    37861 tctttagttt cagacaagta agttgcttcc ttgatttcta gcaggtcaca aaaccaatca
    37921 tttagtccgc ctggtacaat gtcaatattg gtatggctca catagataga aatgtcatgc
    37981 ttgaccaaat ctagaaggat atcacgctga ggggatgaaa ccagatcttt aagcggttta
    38041 aagatgggag catgcttagt tataatgaga tcaacttcat ttttgatggc ttctgctact
    38101 gttgactctc ggatatctaa agtaatcata accttacgaa tgtctttatc caatgaaccc
    38161 atttgaagac ctttaacgtc tccttccata gataaatcaa gtgggcaaaa ggcttcatag
    38221 gcatcaatta gggttttagc tttcatgaac aatcacctct tttatttgtt gtatttttgt
    38281 caagagaagc tgacgctctt gagttttttc ttctgggatg caggacaagg cataagctaa
    38341 cttatccatt tctcgttgcc acttctcttt aaaaacgact gatttttcct gagaaaggta
    38401 tggaccaaaa cgcaattctg tcgcggataa ggccttttca ccatgctcag caacgatgat
    38461 ttcataatat ttgtcatttt cagccatgat ggtttctgca acaattttaa aagcgttaac
    38521 cgataaccaa gcccgtaaat catcctcacg attgttgggc tgtaaaacca gacgttcaat
    38581 gccctgcaat ttttccttac ctgcctctaa aatatcagca atcaaacggc cacccatgcc
    38641 acaaatggta atggctgtca catcatcagc ttcttcaaag gctgcaaggc cattggctaa
    38701 gcgcacctga atatgctcgg caaggccaga ctgtgtgaca tttttaagag cagattcgta
    38761 gggaccccta accacttcgc cagcaatggc tgctgaaatc tgattagttt ctaccaaaaa
    38821 tatgggaaga taggcatgat cactgccaac atctaataat ttgacacctt ttggaacata
    38881 ggccgcaact tgggctaaac ggtttgataa ttgactatcc atcttgattt ctttctaaaa
    38941 cgtaatggtt ctattatagc aaaattacct ccataaaaaa agaaaaccaa aggctaggct
    39001 ttcgattttc cataagtatt ttgatagtac ttgcagtaag actgaacggg acaaatctca
    39061 cattttggtt ttttggctaa acaatggtag cgtccaaaaa aaatcaatcg atggtgagta
    39121 ataatccaat ctttctttgg aattttagcc atcaaatctg cttcaatctg cttgacatcg
    39181 gcatctggtg atgaaatatt gagcctcttt gagactctag ccacatgagt atcaaccgca
    39241 atagctggaa caccataaac ctctgccaat accacattgg ctgtttttcg gccaacaccc
    39301 ggtaaacttt caagctcttt gtgggttttt ggcacttgac ccttaaaatc atcacgaata
    39361 gcctgagcag ttttaatgat atttttggcc ttatttttat agagtccaat cgttctcaga
    39421 gcattttcaa catcagaaag ttcagcaaaa gctaagtctt ctatttctgg ataagactgc
    39481 catagtccag gagttacctt attgacggcc ttatctgtcg tttgagctga taaaatcacc
    39541 gcaatcaaca attgaaaagg tgtttcccag tctaactctc ccttagcctc aggaaacatt
    39601 tgaccaatga tggtcaggac ttttgctaat cttgcttttc caattctcat gaatcactcc
    39661 ataaattcat cgcagataga aaatcctctg atatcgtcac ttgagaaaga tcttcgcctt
    39721 ctctaacacg tctacgttct tctacttgtc gaagattaac aataccttct tttcgccaat
    39781 tacgtaagat agcctggata tatttccaat ttgttttgcc gttgaagaca gcttctttta
    39841 aagcttctcg tatcaaatca ggatctgttt tatcatcacg aagcgttttt tcaagatctt
    39901 ctaactcaaa aggactcaag aatcgtccta attcacgttc aaattcatca actaatcgtt
    39961 tgaaatggtt tggtgtttct tgtttgtcaa tttcagttgc cgtttgactg acaaacaatt
    40021 gatctaactt ggctaacaca ggactcgcat caaaaataat ttcaatttct ccagtaagtt
    40081 caattgtccg catatctaaa agcccttgac tagtcaaaga tgaaatgatt ttattaatat
    40141 cagcaactga ttttccaagc gcatgagcaa tttgactggg tgctaagtca tctcgctttg
    40201 tcgtattttg aagatggaaa aactgccaga ccaaaaaatc atctgagctc ttaaaaagat
    40261 ctttgtaatg aaaaagcaag gcacttggga taaccaaatt acctgactta taatgttcta
    40321 aaaaactcat aatccctcaa tcaaaaggct aaaatcgaat ctatagcctt tactacttta
    40381 aatcccctaa tcagatgctg attaatgtgc ttacccagga aactgcatta agactttata
    40441 gtcatagttc ctaatagcat ggcgaccatt taaaccttct aattcaataa ggaaggcaca
    40501 accagctaca ataccaccaa gtttttcaat catttcaata gttgctttta ccgtaccgcc
    40561 agtcgctagt aaatcatcga caatcaaaac acgttgtcca ggcttaatag catctgcatg
    40621 catagttaag gtatcaagac catattcttt ttcgtaatca gcagagacaa catctcttgg
    40681 cagttttcct ggtttacgaa cgggagcaaa accaattcct aactcaactg caacaggaca
    40741 accaatgata aaaccacgcg cttcaggtcc aacaaccata tcaatatctt tatcacaagc
    40801 gtactgtgct atttcacgaa tagcatagct atatgcttta ccgtcagcca ttaaaggtga
    40861 gatatctcga aacgtaatac cagctttagg gtaatctttg atcgatgcaa tgtaatttgt
    40921 taaatccata gttaattctt tctagtggca aattgccaaa tataaaatac tcttcattat
    40981 atcacgaaac atatttttcg taaaataaga cttctgacat tattgtttat ctgatacttc
    41041 attcgtaact acctcaataa ctactgtcaa ctgctttact tattgatcgt ttgatttcac
    41101 caaataatca tacatctctt tcgggctagc caaagccatg atttcttgaa atttcaccaa
    41161 ttcttttaag tcttggtaaa tgtggctctc tgaaatctct cgtttttgcg cttgggggtt
    41221 aaccgtcatc agcccatcgt caatcgtcac aaaagacaac tcttcaaaaa tttgaatcaa
    41281 cttaatcagt aaaagttttt ctatgtttaa atagtgactc aactctgtca atttatgccg
    41341 taaatcaaat tcaggaaact gatagatggt tttgtagagc ttggcaaact gctctctgct
    41401 gccaaatcct gttaaataat aaggatgttt catctgattt ttaaaataga tggcgtcaaa
    41461 atccttgtga acaaactggt tgcgccaggc tttgaaatct tcagggatgt cattaatcag
    41521 aatgactctg gcatttgggt cttcttcaat agtcggaata ccttcaggaa ctttggctgt
    41581 ttttgtcctt aagtcaagaa gttgcactcc gtcaacacga gcatctacta acatgaattg
    41641 gagactcgtg ttcccattcc aatggttgac agataaggta actgctaatt ctaaaccagt
    41701 agcttgtcgg aactcttgca gttgacttcc ttgaccaaaa gccagtacgt caaaggaagc
    41761 tttgccctga ctgactttaa atttaagatg gctctggtct tgccctatgg tacgcgcttg
    41821 actaaccctt atgtccttga cataaaagac cggcttttga tgatccatcc cataaggggc
    41881 taatttatct aaactcttta aaatatcaag gctaagatcg tccaaagaca gtctttcatc
    41941 aatagttaac gtatttttgg cagtctgatc taagccacgt tctatcacaa actgacaaag
    42001 aaagtctgag agagcttcca agttgtcaac gggcagggtc attcctgctg caccagcatg
    42061 tcccccaaag gctgtaaata actcacgctt gccatttaag gcttcaaaaa tattaatagc
    42121 ttctaaactt ctggccgagc cttttgcaaa gccattatca atagtcaaaa cgacgaccgt
    42181 ttgtccaata gtttccatga tacgaccagc gacaatcccc agaacaccag gatgccagcc
    42241 agcttgtgcc aagacttgaa caggtttttg aggatcaacc atagccatcg cttgatcaaa
    42301 aatgtcttgg actaaggcct tacgctcttc attttttttc ttaatcatca aggcaatcgc
    42361 ttgagcttct tggtcatcaa agcccgtcag tagctcaatg gctggattag ggtcatctaa
    42421 gcgccctaaa gcatttaatt gcggagcaat ctgaaagcca atggcgtctt cattaaaatg
    42481 ttccaaatca ataggagaca aggacatcaa ctcctgcaag cccactcttt cggtgtgttt
    42541 gagcatggcc agaccatttt tgactaaaac acggttttca cctgtcaagc ttaccatatc
    42601 ggcaatggtt ccaatagcta ccaagtctag acagtctgtt ggtaaacttt ctagcaaagc
    42661 tgttgccaat ttaaaggcaa cgccacagcc agctaagtgt ttaaagggat aatcagcatc
    42721 aggatgctca ggatgaatga tggcaaaggc ttctggcaat tcttcaggca ggctatgatg
    42781 gtcagttaca atgacatcaa cttcctgttc ttgagcatat ctaatcgctt catgtccggc
    42841 cacgccatta tcaaccgtga taattaggga cacagcttcc tgctcaataa aatatttata
    42901 gacgctctgg ttggggccat agccatctgt aaagcggttg ggaagataaa ccaaaggctc
    42961 tgctcccatc atgtctaggg tttctttgac aatagaagcc gacgtcatgc catcagcatc
    43021 atagtcgccg taaatgagaa ttcgttcgcc ctcttcaata gcttgacgaa ttcttggaac
    43081 agcttttgcc atgtcatgta gcaagtaagg atcatgcagt tgagacaagt ccgctgttaa
    43141 aaactcatct aaggcttctt cagtccttat ccctcgatca taaatcaact gagcggcggt
    43201 ctgggttaga ccttttgtct ttgctagctt aaagaagcca tcatctggct tcttgtcttt
    43261 tattttccag ctatatttgg atttaatcat ttataattaa atacctttct tgcaagataa
    43321 tcagataatt tagggaaaag ggtgtaaaat tgatgggtca ccgctaaact aaagggcaaa
    43381 ttcaattctc gtttattttt cccgataata gaaaccaaac gcttagccac ttgatttggt
    43441 tggagagtaa atttaccaac gctttccaaa taatgtccag acgggtcagc ttggttaaaa
    43501 aacttggtgg caatgggacc tggattcacg gtggtcacgt aaaccccttt atccgctaat
    43561 tctaagcgaa gggcattgga aaatccgata agggcaaact tggtggctga ataaatgctc
    43621 gatttggctg acgcaatcaa gcctgccatg gacacaatat taataagatg accttgcccc
    43681 tgctctgcca ttttctgacc aatcaagcaa gcaaagtgaa tgctcgctag ggtgttaacc
    43741 tgaaacatat cagctatttc tttggcagaa aactcttcaa agcctttgaa agctccataa
    43801 ccagcattat taatcaagac atcaatacgg ccatagcgct ggtaaatctg ggcgactatt
    43861 ttctcaatgg ctactggatt ggtaatatcc aactcaaggc attctttgtt gtcaatatgc
    43921 tgataacagt gttctaggcg ttctttgtta cgtcctaata aaatcaagct gtcttccttg
    43981 ggtaactgct taacaattgc ctgagccagt cctccagaag ctcccgtgat aacaatgatt
    44041 ctttgtgcca ttaaataatc acttcctcta aatcttgtac cattttaaca ttttcaaata
    44101 tagtggcggc atctttttcc atctggcgac aatcacgccc taaaaagcga gctgatacat
    44161 gattgagcaa gaggcgtttt gcgcctgctt catgagcgat ttgtgctgcc tgcatgttgg
    44221 tagaatgccc gtgatttctc gcaatccgct cgtcaccctt accataggtg gattcatgaa
    44281 ccaaaacatc tgcatcttta gcgagtttaa cactggcaga cgttttgcgc gtatcgccga
    44341 taatggtgat gattttgcct tttttagggg cagaaatata atctttggca caaatcaggc
    44401 ggccgtcttc caactcaacg tcttgaccat ttttaatttt gccaaagagt ggtccaaaag
    44461 gaacacccgc tgcttttaag gcttctgcgt ctagggttcc ttctaagtct ttttgaacta
    44521 ctcgataacc catgcaaaaa atggtatgcg ccagacgctc tgcatagacc tcaaacttat
    44581 ctgtttccat tattttacct aatgatttgt catcaaattc atgaaaatga atctgataag
    44641 gtacacgcgc tccagaaact tttagactag ttaacacgta agttttaatg ccaattggtc
    44701 cataaatatc aagatctgtc tgttcttcac tagcttgaaa agaccgactt gataaaaatc
    44761 ctggtaatcc aaaaatgtgg tctccatgca aatgagtaat gaaaatcttt cttatttttc
    44821 gtggcttaat cgtcgtttct aaaatttgtc tttgcgtccc ttcaccgcaa tcaaacatcc
    44881 agacttcatt gatttcgtct agtaatttca aggcaagact tgacacattg cgctgcttgg
    44941 ctggttgacc agctccagtt cctaaaaatt gtaattccat tcaatctatt ctttctattg
    45001 ggtgatgtaa atcataaatt ctcgttgggc aaaatcataa tacttttgac cagaaaatgt
    45061 ttggctaaga gcccataact cctctacatt aaacccctta agcatggtga taccgtttgc
    45121 cagacgataa atcttcgaca agagtgtgtc atcaggcgta atgtcttcac attctccttg
    45181 ctcaaactgc ttagcctgca ttttaagctg gcctttgtct tcataaacca tatattgtgg
    45241 gaaaatttgt gttaattcaa agaagagttc gggtttctta ggctctgctt tttcagaaaa
    45301 taccaatgca acttcttggt cattttggta agcaaaacca taagcttttc cagacaaatt
    45361 gaggcgtaca aagggctttt cttcctcaaa agatggttgg tcagtaaaaa gccccaaagc
    45421 cttagaaaga ttaaaataat aatcagtcgc agcttgcggt gactgtttct ggtagatttc
    45481 agcaaagtag gcattaataa cacttggtgg tggtgtgata aaagctagtt tttgctggtc
    45541 tgtcaaactg gctaacagat ggtttaggta gttggtatcc agactagtaa atccaccata
    45601 ggtttttgct aaatcaatat aattattcat aaaaatcgtc aagtctccat tgctgttttg
    45661 gggaaatgta gcccgaaata tcctctattt cttggtcaaa cgtgtagtgg tccaaaagag
    45721 caactcggtt caaatcatac agcttgtacg ccttgtcttg atgcactttg attctaaaag
    45781 gaacaaactg gtctcgaatt tggtcaatga ttaaacgtct caagagaatt ttgctatcct
    45841 ttgaacgggc tgaaatcctg atatttggaa aagcagtagc tgtgaattgt tctgctatat
    45901 ccaccttgtt ataaatagct aaacgtggaa tattaagcat gtctagctct tttagaaggt
    45961 ttaaaaccac tttttcttgc tcactatgat tagggtcgct agcgtcaatc acatgtaaca
    46021 gcaaatccac atatttgctt tcttctaggg ttgatttaaa agcagccact aattccgttg
    46081 gcaagtcttg aataaagcct acggtgtctg ttaaggttgc ttgaaattga ttttctaaat
    46141 agagttgctt tgtagttgca tctaaggtag caaataattc attggcttca tagtggctgt
    46201 catctgtcaa caagttcata atggttgact tgccagcatt ggtgtagcca atcaagccaa
    46261 ttttaaaggt atctgaaccc acacgacgat ctctaatggt ttgacgattt ttctctacct
    46321 gagttaattg gcgttcaata tcagcaatct gatgacgaat cgaacggcga tttaactcta
    46381 gttggctttc acctggtcca cggctcccaa taccacctgc ttgacgactt aacatgatgc
    46441 cctgtccaac caaacgaggt aacatatatt tcaattgggc aaggtgtact tgtaatttgc
    46501 cctcatggct tctggcacgc atggcaaaaa tatctaagat taactgcata cggtcaatga
    46561 cttttacctc taaaacagct tctagattag cattttgcct agcagtcaac cgattgttca
    46621 caataactgc atcaatctca tcagcttcca caatcgcctt aatctcatcc agtttccctg
    46681 agccgataaa ggttttgctg tcgtaacgtt ctcgtttttg gctgaaactt gccataactt
    46741 tgacgccagc tgtcttggca agattagcta attctgtcat ggacatgtca aaatgttctg
    46801 ttgtctgaag ctcaactcct aaaagaatca ctctttcttg ctgacgcttt gtctcaacca
    46861 tcacctttac caatcctcca aattccgtaa attctattat aacatatctt caacagattc
    46921 tgctaatttt gcgtcatgac ttctctttct gaccaagaaa atccctgacc ctatcatgta
    46981 ctacctgtgg gtaatcagga gccgttatgg cagtgaagct aacagccatt cgattgcgga
    47041 accaagttag ctgtcgcttg gcaaaacgtc tcgtgttttg ttttaactga tcactagctt
    47101 ctgccaaagt catttcacct acaaaatagg ggaataattc cttataacct atgccacgac
    47161 tagcctgaac agtcgggtaa tgctcatata accattttgc ttcttccaac aagccgtttt
    47221 caagcatatg atccacgcgc tgattgatac agtcatagat gacttggcgg tcatcattca
    47281 agccgataat aagcggctca taagccgtct cggcattctc taattcatca gcaaactgag
    47341 ccaattcaag ggctcggatc gcccgcctgc gattcacctg ctcaatggta atgttattga
    47401 cttgcaagcg ttcatacaag tcgtgatcgt ctagttgctc caactcattc cgataggctt
    47461 ttacagcctc ttggtctact gttcctccta agtggtaacc ttcgagtaaa ctttgtaagt
    47521 aaagaccagt tccacctaca ataattggta atttcccacg actaacaatg tctgaaatag
    47581 ctttttgagc atcttggaca aactcgtagg ccgaataaga ctccgtcacc tcacgaatat
    47641 caattaagtg atgaaccgct gcttcttgct cttcttgagt ggccttggct gttccaatat
    47701 ccaactgtcg ataaacttgc tggctatctc ctgaaataat ttctccatta aaagccttgg
    47761 ctaaactaat cccaagtgct gtttttccaa ccgctgtcgg accaacaatc acaactattt
    47821 ttatttttgt cattttcttg tctttctatt agaaaagcgt gtccaaaaac gccttttact
    47881 tgaaaattag cttatttttc gctaccatat attataacat aagattaagg accactgagg
    47941 tccttcacta gaaatggaga ataatcatgg ttaagaaata tcaatttgtt aaaggtcttg
    48001 ctactggcgt cctagcaact gctgctactg ttgctggtgc tgtctttgct gtaaaaaaaa
    48061 caatcattga ccctgaagaa gaaaaagctg ctttcattga agaaaaccgc aaaaaagctg
    48121 cgcgtcgtcg tgtagctcgc taacgtgaca atggatcaat ttaaaagaga ctagcacatt
    48181 aaagtgccgg cctctttttt agtaatctcg ataactagtt agtagtaact gtctcttgat
    48241 gagccaagat gttagctgct ttacttattt tgaaatagaa atctcaggta agccccataa
    48301 acatacgtga ctaaagctgt cgccaacaat acctctccta gcaaaagaac ctgccaacct
    48361 aaaccttgcc aacctaaaaa agataaggtc atttttaagg aagtggcact aatcacaaac
    48421 ggaaaggtaa aagctgaaaa acctgggtta aagggacgat tgagtaagcg aggaagctgt
    48481 acaaccacaa aagcatataa cagttgtgag ctgatgagaa gaaagataac cattcctact
    48541 tgtggtctag gaaaggttgc taaataagac gctgaaagta aggacagagg ggcacaaaac
    48601 gttgaaatat tgggcattac tgcttgacct aaaccaatcc cataagtctt tttggccata
    48661 aaaggtaaaa tcacagcagt taagagaaga caaacccaaa aaatcacctg tcctaataaa
    48721 aactgcctac tagcaggtgc tgttaatgcc gccattgcaa ttccaacaaa aagcacggac
    48781 caggaaggag aaacgttatc ccatgaaaaa gaaaagacaa aacgatactg gtaataagca
    48841 atcaggacaa gatttcccca aaagaatagc caccaagtga gaaagcctaa ccaacaccct
    48901 cctgtcactt tgagaaagag tgaagacaac aacatccctg tcataaaaaa agttggaaaa
    48961 acagaggcaa ttagaggttg tcgtaactgc attttggtat cgttaaggtt cctaaccatg
    49021 ccaacaagca agataccata gataaaaaga gctgccagaa ttcccaaata attaaaaatc
    49081 gaaacataag tagccaacaa attgccaaat gacaacgttc ctaatgccaa tcctgacatg
    49141 accaatggtg ggtttttaag gtgtttcata agtgtccttt tctgcctatt aacagctatt
    49201 tttagtgaca taatcttgtt tattttatca catttcgagc atttttgaca ccacccgcga
    49261 aagaaaattt aaggctcttg ccattgtttt tttacattct cgcaaaacta gcaaactgct
    49321 taaaaagcta aggagtaacc actcttctct agaaaaatga aagagtagag aagacttggt
    49381 ctgatcttta cttcttcttt ttgatttagt gagctgcatt aagcacttgt tgaacagctg
    49441 aatcttccac aatttttgcc ataaaggctg ccagatgcgg ataattctcg taagattttg
    49501 gtgttttttg agaccatagc gccatggcgt aagcataagc atctgcaatg gtttgttgat
    49561 ctcgataaac atgcccactc tccccaataa gaccatctaa atgcgtcata gcaataccca
    49621 tccgcttgta agaagcttgt ttgacttttt caagcgcttg attgtcttga gaaatagtgt
    49681 agcgatgagg gttgaacatt ggcctaaaaa caaagggaaa atcacctgtt aagtagtcca
    49741 tgatttcgtt gaaccgactg tctgccaaaa gattatcttg gggaatgagc tgagatttca
    49801 gggtttgttt cgctataaag ggcaagataa tacctgcctg tgtgacaatt tgaccatcat
    49861 caagctgtaa agcttaaacc attcccaaag gattgatggt aaggcagtct tcagaatcca
    49921 gttttacctt ctctacctcg taatacagaa actcacaatt cttttgaaaa ggttctagac
    49981 agagttggtg ttgacgtctt cgctgttgat ggctctgcat gacaaaatga gcttggtgtc
    50041 cacgttcact tgtatcttgt tgcaaagtct ttgcaatttg gtctcatcat ctgtatcaca
    50101 aaaaacaaac cagtttcctg atttgttttg agatattaga cacctacaaa ttctggcaag
    50161 gattctccga tagcttctaa acgttctgcc cattcttgac gtgataaacc attttcttgc
    50221 acatagcgat tacgttcatg tgcacgacat tcaggcgagc accctcgaac atacttcgtt
    50281 tcgttttctt ctgaagcaaa aatttgtttg ttacaaaacg gatttgcaca attgacataa
    50341 cgttcacaag gtgttccatc aaaataatct ttactaatga cagttggatt aacatgatta
    50401 attggcaccg agatacgatc atcaaaaaca tacatcgcac catcccaaag ttcaccttga
    50461 acttccggat cttttccata tgttgcaata ccaccgtgta attgtccaac atctttaaag
    50521 ccttctcgaa ccatccaacc cgagaatttc tcacagcgaa caccacccgt acagtacacg
    50581 acaacacgtt tttccataaa cttatctttg ttgtcacgta cccattgtgg taactcacgg
    50641 aaattgcgaa tatcaggacg aattgctcca cggaagtgac ctaagtcata ctcataatca
    50701 ttacgcgtat ctaaaacaac agtatcttca tcaagcaagg cttctttaaa ttgtttagga
    50761 tttaaatact cacctgttgt ttccaaagga ttaatatcac tatcaaagtt attgtcttct
    50821 aacccaaggt gcacaatctc tttcttataa cgaacaaaca ttttacggaa agcttgttga
    50881 ttttcctcgt caatcttgaa ccaaagatca gcaaaacgct catcgctgtg gacccaatcc
    50941 atatacttct gagttgtttc ataatctcca gaaacagttc cattaatccc ctcatccgca
    51001 atcaaaatac gacctttaag cccaatagat ttacaaaatt ctagatgttt cgcagcgtac
    51061 tcttgcgcat tttcaattga aacatactta taatagagta aaactctgat tttttctgac
    51121 attttttctc cttcattgtt attcagttac ttcctattat atctaggaaa aacaagtcta
    51181 ggcaagccat ttgtttgtct tttttttcac aaaatagatc tcaatttatt tttgatgaga
    51241 tggcaatcca ttactccttt aagcaaatca ttagaagctt tatttagaaa atgctaagat
    51301 aaaacaagga ggccaaaatg acttatgaac tttgtttaga atatgggact tatccgttgt
    51361 cacgtgttga tgcttactgg ggagaagatc aaaatccccc aacattcatt caagaagatc
    51421 gactgctttg ccataaacta gaaactatga atcacctgtt ccatgattta tttgtaacta
    51481 ttgaatcaca attccattat gttggtttta acatgcctga aaaaagagcg cagattcgga
    51541 tactatatca agaagtagct actatattaa aatgcaaata taaggattat ccaattaaga
    51601 ttgagacgtt tcttctttaa aaatctaata ctaaaaaact aactgtgctt agacagatga
    51661 cacagctagt tttttaggta aaactcttct taaattttaa aacgtttcga aaaatcacta
    51721 aatgctttaa tagcacttgc taaaaatggt ttcaccatct catcaataat taaccttgat
    51781 tacttacaat cttatgaatc tgagtcaaat aaaattcagg ctgtggcatt acagagacat
    51841 ttaaaaccta tactcatcgt tttcaaggtc agaaagagaa tgattttgaa aaggttcgtc
    51901 aactcttcta gataattttg gacaaatttt gatcaagaaa caaaaagagc ctatcaaata
    51961 aggctttttt atatgatttc tatccacctt gagggaatcg aacccccatc tcaagaaccg
    52021 gaatcttacg tgatatccat tacactaaag gtggtcacaa ctttgtc
//
LOCUS       DAUGOH010000011        52041 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUGOH010000011 DAUGOH010000000
VERSION     DAUGOH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52041
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.011"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            101..376
                     /locus_tag="VH957_000655"
     CDS             101..376
                     /locus_tag="VH957_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEQ8558591.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            710..2572
                     /gene="cadA"
                     /locus_tag="VH957_000656"
     CDS             710..2572
                     /gene="cadA"
                     /locus_tag="VH957_000656"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEQ8558592.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYTSAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAEAASTHPISKAFLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYTLLDDIKI
                     ESKRAIKSLHDMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(2872..3807)
                     /locus_tag="VH957_000657"
     CDS             complement(2872..3807)
                     /locus_tag="VH957_000657"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEQ8558593.1"
                     /translation="MVSTATQISHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLFFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            4046..4741
                     /locus_tag="VH957_000658"
     CDS             4046..4741
                     /locus_tag="VH957_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEQ8558594.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            4848..5369
                     /locus_tag="VH957_000659"
     CDS             4848..5369
                     /locus_tag="VH957_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEQ8558595.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            5530..6072
                     /locus_tag="VH957_000660"
     CDS             5530..6072
                     /locus_tag="VH957_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558596.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            6196..6975
                     /locus_tag="VH957_000661"
     CDS             6196..6975
                     /locus_tag="VH957_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEQ8558597.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFATNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            7772..8368
                     /gene="recR"
                     /locus_tag="VH957_000662"
     CDS             7772..8368
                     /gene="recR"
                     /locus_tag="VH957_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEQ8558598.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            8469..9515
                     /locus_tag="VH957_000663"
     CDS             8469..9515
                     /locus_tag="VH957_000663"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEQ8558599.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            9706..11097
                     /locus_tag="VH957_000664"
     CDS             9706..11097
                     /locus_tag="VH957_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEQ8558600.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDICLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            11177..11872
                     /locus_tag="VH957_000665"
     CDS             11177..11872
                     /locus_tag="VH957_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEQ8558601.1"
                     /translation="MDFFAIDPIGLPHISLIFYLLSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLAFAFSKEK"
     gene            12120..13664
                     /locus_tag="VH957_000666"
     CDS             12120..13664
                     /locus_tag="VH957_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEQ8558602.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLTKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTSKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            13971..15590
                     /locus_tag="VH957_000667"
     CDS             13971..15590
                     /locus_tag="VH957_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8558603.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            15717..17716
                     /locus_tag="VH957_000668"
                     /pseudo
     CDS             15717..17716
                     /locus_tag="VH957_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
     gene            complement(17740..18018)
                     /locus_tag="VH957_000669"
     CDS             complement(17740..18018)
                     /locus_tag="VH957_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEQ8558604.1"
                     /translation="MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(18008..18862)
                     /locus_tag="VH957_000670"
     CDS             complement(18008..18862)
                     /locus_tag="VH957_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEQ8558605.1"
                     /translation="MKVDFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
                     KGKPNHDH"
     gene            18902..19642
                     /locus_tag="VH957_000671"
     CDS             18902..19642
                     /locus_tag="VH957_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEQ8558606.1"
                     /translation="MFYAYLRGLVVFLLWIVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKMAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            19842..20504
                     /locus_tag="VH957_000672"
     CDS             19842..20504
                     /locus_tag="VH957_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEQ8558607.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            20485..22728
                     /locus_tag="VH957_000673"
     CDS             20485..22728
                     /locus_tag="VH957_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEQ8558608.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVFFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
                     FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FASFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRREYHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPIFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGWTS
                     WHLETVR"
     gene            22799..23839
                     /locus_tag="VH957_000674"
     CDS             22799..23839
                     /locus_tag="VH957_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEQ8558609.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSYQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKVDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            23936..24541
                     /locus_tag="VH957_000675"
     CDS             23936..24541
                     /locus_tag="VH957_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEQ8558610.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
     gene            24708..24941
                     /locus_tag="VH957_000676"
     CDS             24708..24941
                     /locus_tag="VH957_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558611.1"
                     /translation="MLREKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGERQQTA
                     DLKMKSKIRKTVQKPLPEKSKEAKQAVMDADLA"
     gene            25166..25756
                     /locus_tag="VH957_000677"
     CDS             25166..25756
                     /locus_tag="VH957_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEQ8558612.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSIPDMQEYSLVCSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTAYYLQVLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLIALYSSGL
                     GGATQASEEVNGLGYVQLVQLTYVINEWHRVNHNMI"
     gene            complement(25910..27130)
                     /locus_tag="VH957_000678"
     CDS             complement(25910..27130)
                     /locus_tag="VH957_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8558613.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSALIQACYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLIHHY
                     QETRGDNKTSKTQH"
     gene            complement(27137..28165)
                     /gene="queA"
                     /locus_tag="VH957_000679"
     CDS             complement(27137..28165)
                     /gene="queA"
                     /locus_tag="VH957_000679"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEQ8558614.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGSKFQGDIQADSG
                     WTNIFIKPGYQFNVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            28367..29071
                     /gene="nagB"
                     /locus_tag="VH957_000680"
     CDS             28367..29071
                     /gene="nagB"
                     /locus_tag="VH957_000680"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEQ8558615.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDI
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            29190..29906
                     /locus_tag="VH957_000681"
     CDS             29190..29906
                     /locus_tag="VH957_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8558616.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            30202..31164
                     /locus_tag="VH957_000682"
     CDS             30202..31164
                     /locus_tag="VH957_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEQ8558617.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     CLSFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            31177..32982
                     /gene="pepF"
                     /locus_tag="VH957_000683"
     CDS             31177..32982
                     /gene="pepF"
                     /locus_tag="VH957_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8558618.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFS
                     GHLLDSSANLLTITDTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            33358..34554
                     /locus_tag="VH957_000684"
     CDS             33358..34554
                     /locus_tag="VH957_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEQ8558619.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            34620..35327
                     /locus_tag="VH957_000685"
     CDS             34620..35327
                     /locus_tag="VH957_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEQ8558620.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLRVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            35390..36445
                     /gene="prsA"
                     /locus_tag="VH957_000686"
     CDS             35390..36445
                     /gene="prsA"
                     /locus_tag="VH957_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8558621.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            36832..39450
                     /gene="alaS"
                     /locus_tag="VH957_000687"
     CDS             36832..39450
                     /gene="alaS"
                     /locus_tag="VH957_000687"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEQ8558622.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRN
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYDPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            39790..40005
                     /locus_tag="VH957_000688"
     CDS             39790..40005
                     /locus_tag="VH957_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8558623.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            40002..40763
                     /locus_tag="VH957_000689"
     CDS             40002..40763
                     /locus_tag="VH957_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEQ8558624.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVFSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            40782..41477
                     /locus_tag="VH957_000690"
     CDS             40782..41477
                     /locus_tag="VH957_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8558625.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVSTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(41569..42726)
                     /locus_tag="VH957_000691"
                     /pseudo
     CDS             complement(41569..42726)
                     /locus_tag="VH957_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(42822..44135)
                     /locus_tag="VH957_000692"
     CDS             complement(42822..44135)
                     /locus_tag="VH957_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEQ8558626.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASSAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(44110..45069)
                     /gene="nrdF"
                     /locus_tag="VH957_000693"
     CDS             complement(44110..45069)
                     /gene="nrdF"
                     /locus_tag="VH957_000693"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8558627.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(45402..47561)
                     /gene="nrdE"
                     /locus_tag="VH957_000694"
     CDS             complement(45402..47561)
                     /gene="nrdE"
                     /locus_tag="VH957_000694"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8558628.1"
                     /translation="MSLKDIGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSNLVKSLFKDHFIPQAEDWKALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(47581..47799)
                     /locus_tag="VH957_000695"
     CDS             complement(47581..47799)
                     /locus_tag="VH957_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEQ8558629.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            48192..48455
                     /locus_tag="VH957_000696"
     CDS             48192..48455
                     /locus_tag="VH957_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEQ8558630.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            48460..50193
                     /gene="ptsP"
                     /locus_tag="VH957_000697"
     CDS             48460..50193
                     /gene="ptsP"
                     /locus_tag="VH957_000697"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEQ8558631.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            50378..51805
                     /locus_tag="VH957_000698"
     CDS             50378..51805
                     /locus_tag="VH957_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8558632.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALISGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLVLAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            51900..>52041
                     /locus_tag="VH957_000699"
     CDS             51900..>52041
                     /locus_tag="VH957_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deacetylase"
                     /protein_id="HEQ8558633.1"
                     /translation="MKKLNVILVGLLSILILSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSD"
BASE COUNT        16007 a         9134 c        10774 g        16126 t
ORIGIN      
        1 aagctcaaat aacgttaaat acttgaccta atcgcttttt ttagatatga taatatctgt
       61 taaagcatta agcttactaa ttatttggag gatttgttaa atggctaaca aacaagattt
      121 aatcgcaaag gttgcagaag caactgaatt gactaaaaaa gattcagcag cagcagttga
      181 tgccgtgttt tctacaatcg aagctttcct tgctgaaggt gaaaaagtac aattgatcgg
      241 ttttggtaac ttcgaagtac gcgaacgtgc agctcgtaaa ggtcgtaacc cacaaactgg
      301 tgcagaaatt gaaattgcag cttcaaaagt tccagccttc aaagctggta aagctcttaa
      361 agacgctgtt aaataattcg tctagaaaaa tcttgttgct atcgatgttt attgatagcg
      421 acaaggttct ttttttatat ttggggcata aagttagtag ttttctcttc agttaagcca
      481 agttctaaag catgcactct ataatggtca gtcatccttc tattagtata tcatttccgc
      541 aggtaggggg agtttttttc atatttgcaa atagttgaag ttaggatttt tgaaagcaaa
      601 aggtaagttt atttagaatg tttctaaatt acttgactta tttatttaga attattataa
      661 ttaatatatc ttaaagattg aataactttt aattgcgagg gaactaaaaa tgacaatcag
      721 acaatggatg gcagaccatc ttcatttgat ggagacttta gcgtgtttgg tattaataat
      781 aattggccta gcctttttac actcatttcc acaagtggct tccgctattt tcattacagc
      841 cttcttgatt ggaggatata cgtctgcaaa aacgggtata ttggatttgg tgaagaacaa
      901 acacttgtca gtggatattt tgatgatttt ggcagctatc ggtgctggaa ttatcggcta
      961 ttggctggag ggtgctctgc ttatttttat cttttcgttg tccaatacgc ttgaagaaat
     1021 ggccatggaa aaaagtaagg atgctatttc agccttgatg tccttgacgc cagatacagc
     1081 tcgtcaatac caagaagatg gccatatttt agaagttgag accagatcct tgagtgttgg
     1141 tgaccgttta caagttcgta aaggcgaagc tgttccaatt gacgggcagt tgcttagtcc
     1201 ttttggtcaa tttgatgaat ctatggtcac tggtgagcct atcactgttg ataaggcaga
     1261 aggccaggat ctgattgggg gaaccattaa ccaaggacaa accatagata tgttggttac
     1321 tattgaaaat gacgatactc tctttgccaa gattattaat ctggtggaat ctgcccaaga
     1381 aaagaaaagc aaaactgcca cctttatcga aagcttagaa gatggttatg tcaaatttgt
     1441 gctcgtcctt attcctgcct ttatcctctt tagccacttt gtgctttctt ggacttggtt
     1501 ggctgctttt taccgaggga tgattctctt aacagtagct tcaccatgtg ccctaattgc
     1561 cagttccaca cctgctagct tggctgctat ttctcgtgca gccaggaagg gattgattat
     1621 caaaggaggg gatattgtcg ataacatggg agatattaag gctgttgtca tggataaaac
     1681 gggaacgctc acccaaggaa aaccttctgt tgtgaatgct cattatttgg aagatgagtt
     1741 gctcgtgaat agactggtaa aaggagcaga ggctgctagt acccatccta tttctaaagc
     1801 ctttcttgaa tacactgaaa aattggagcc actgaccttt gaccacttag aagaaatttc
     1861 tgggaaaggt tttcagggct tctatcaagg gcaagaatgg cgaattggca agaaaacatt
     1921 cattttggaa aaggttcaag acctatcagc ttttgaagaa actattcaag tggaagaaaa
     1981 tcaagggaaa accctaatct ttgtttcacg tgaccatcaa ttgatagctt actataccct
     2041 cttggatgat atcaaaatag aatcaaaacg tgctattaag tctcttcatg acatgggaat
     2101 caaaacagtc atgttaacag gtgaccaaga acgaaccgcc aattatgtgg cacaaaaact
     2161 tggtattgat gaagtggtag ccaactgtat gcctcaagat aaggtggcta agttagcaga
     2221 attaaagacc aaatatggtt ttgtggccat ggtaggagat ggtattaatg atgctcctgc
     2281 ccttgctcaa gcagatgttt cttatgctat tggatcagga acagatattg caatggaaag
     2341 tgcagacagt gtgattatgg atgacttgac tcgtattcca ttttcgattc aactttcccg
     2401 caaaatgaag accattatca aacaaaatat tgtttttgcc ttatctgtga ttaccttatt
     2461 gattttagcc aatgtttttc aggtagttaa cttgccgctt ggtgttgttg gacacgaagg
     2521 ctcaacgatt ttagtgattt taaatggctt gcgtttactt tcttttaaat aatttagaaa
     2581 cttgcttgaa aacttgaaag tgtttataat aatagtaaga cttatgaaag agaaaaccgc
     2641 cgtatgttta ctattatgat cattggttta gctgtatttt caataattaa aatcattcta
     2701 tttttctatt tttatcagca atttgagcgc aagcaaaaaa gaaaagttga atcaaacaac
     2761 cagcaaagac agtcccaaga aagtgacgct gtcccttcaa aaaaattccc attttaaaaa
     2821 gcttggaaag tgtacaaagt gcacatttcc aagctttttt gactattaag gttaatcttt
     2881 gtaacgtaag ttcccacgaa aatcgtctaa gctttggtag cctttttcta ccataatcgt
     2941 ttttagttcc ttagtgaccc gttcaaagat agctggccct tcttgatgaa gggctgttcc
     3001 aatttggacc atgcttgcgc cacaaagaat atgttcaaag gcatcgcgtc ctgttttaac
     3061 tccccctgta ccaataatgt ggatagaagg ttttaagcgt ttgtaaaacg catggacatt
     3121 ggctagagca gtaggtttga tgtaatctcc acctatacca ccaaagccat ttttaggctt
     3181 gatgaggact tgctcatcct caatgaccag cccatttccg atagaattga cacagttcac
     3241 aaagaaaagg gggtatttat tgaaaatcgc agccgcttga tcaaaatgca caatgtcaaa
     3301 ataaggaggt aatttgatac caagaggttt agtgtaatag gtaaagatgt tctctagaag
     3361 ttgatcagtg gtttcaaaat cataagcaat ctgtggtttt cctggaacgt tcgggcaaga
     3421 aaggtttagt tccactagac cctcataatc tgaagccatg atggctttta aaatggtttc
     3481 ggtttcagta ggagatagcc cgacaacgga gagaaaatga ggtttatgtt gcccggtttt
     3541 ggcaagatca ctgacaaagt ctaagtagta gcgaaaacca ttattaggga gtcccattga
     3601 attgatagaa ccaagacgag tatctgcgta gcgaggttct ggattacctg gacgaacttc
     3661 aagcgtccct gttttggtga caaaggaagc ggcttgagac ttttcaacct ccataagctc
     3721 ttcttttgtc atgcagtaaa caccagcagc attcatcaaa cagttatcaa aagagaaatg
     3781 actaatttgt gtagcagtag aaaccattat ttcctccata ttttagacaa attttttcta
     3841 ttctaccact aggcatgaat aatagcaagc tatttttaca aaaatgtaaa tatattactg
     3901 ttattgacga acatttgaaa ttttcatgat agttacatta tgattttcaa taaagtcaga
     3961 atagactagc ttttttgcta tattttttgt aaaataggaa ttgtaaaaag gtagcaacct
     4021 ttaaattaaa aggagatatt aactcatggt aaaattggtt ttcgctcgcc acggtgagtc
     4081 agaatggaac aaagctaacc tcttcactgg ttgggcagat gttgatcttt cagaaaaagg
     4141 gacacaacaa gcgattgatg caggtaaatt gatcaaagaa gcaggtattg aatttgacct
     4201 tgctttcact tcagtattga cacgtgctat caaaacaact aaccttgccc ttgaaaatgc
     4261 aggtcaattg tgggttccaa ctgaaaaatc atggcgcttg aacgagcgtc actatggtgc
     4321 tttgactggc aaaaacaaag ctgaagctgc agaacaattt ggtgatgaac aagttcatat
     4381 ctggcgtcgt tcttacgacg tattgccgcc agctatggct aaagatgatg agtattcagc
     4441 acacaaagac cgtcgttatg ctgatcttga cccagccctt attccagatg ctgaaaactt
     4501 aaaagtaact cttgaacgcg caatgcctta ctgggaagaa aaaattgctc cagctcttct
     4561 tgacggtaaa aacgtctttg ttggcgcaca tggtaactca atccgcgctc ttgtgaaaca
     4621 cattaaaggt ctttcagatg acgaaatcat ggatgtggaa attccaaact tcccaccact
     4681 tgtttttgaa ttagatgaaa aacttaacat tgttaaagaa tactaccttg gtggtgaata
     4741 acttaaaaac cagactttgg tctggttttt tgattctata tcctaagaag aaagaaaacc
     4801 ctgcttaaaa atatgatatg atagaaataa aaaaggatag atagattatg aaagcagaag
     4861 atcgtcgtca aaaaattatt gagtgcttaa atagtgaaca aaaagctgta tctgctactc
     4921 gtttaggtaa gttattagga gtgagtcgcc aagtaatcgt tggagatata gctcttcttc
     4981 gagctcagca gattgatatt atttcgactc caaaaggtta tattatgtca acagcgcttt
     5041 atagtcacca attttgtgca cgtattgtgt gccaacataa tgtagaagaa actaaaaaag
     5101 aattagaaat tattttagct catcaaggga ttattacgac ggtagaggta gaacatccta
     5161 tttacggtat gataacagcc cctttaaata ttaagacaca ctctgatgta actaatttca
     5221 tgtccaaact cagtcaatct aaagcagagt tattgtcttc gttgacagaa ggactacata
     5281 gtcacttaat ttcgtgtcct agtcaagaag cctttttagc tatcaagcat gatttagaat
     5341 tagcaggtat cttatacaaa ggaatataac tacagtatat tatgccattg atggttgtta
     5401 tgaataccat gctaaaatat tctattgatt atttatcagc aacaaggtat cgtttaaaaa
     5461 taccaaaaga tacaggtgtc ttgatagtta ttggttttta aggtatacta tttttgaaaa
     5521 ggagataaaa tgactaaaaa accaacacaa ctaatagctt atacctctat tttggtcgca
     5581 tttgcgattt tgattccgat aatcatgcct cttaagctta ttattggacc agcttccttt
     5641 actctggcga gccatgttcc tttgtttttg gctattttta tgtcgattcc agtagcaatt
     5701 ttggtcgctc ttggtaccac attaggtttt ttattagctg gacttccttt aattattgtt
     5761 ttaagagcac tctctcattt attgtttgct attttggcag cgtggtggtt aagtagaaaa
     5821 ccacaactga tgacatcggc agtaaaatgt tttagttttg cgtttttcat taatgtcatt
     5881 catggcttgg ctgaattttt agttgtctat attttaacag caaccacagc aacttctatg
     5941 tcttattttt ggtctatgct aggcttgatt ggcttaggtt cgcttattca tggcatattg
     6001 gatttctatc ttgctttagt tctatggcgt tttttagcaa aaaacttaaa acttcccacc
     6061 ataaatgcct aagactaaaa tagagatagt tatatgataa tgacgagccc tttcttgttg
     6121 aaagggcttg cattttttag gaaaattgat atactaaagt gtgtgtttgt gaatacagta
     6181 acaaaaggag atatcatgaa aacaccagaa cagattttag aagcaactat tcatattggg
     6241 gaacataagg ttaccaaaac ttttttggct aaatctatct taggctttat tggtggagcg
     6301 atgattagcc ttggttattt actctacgtg agaattgccg ccagtggttt agaaactttt
     6361 ggtgcttttt ccagtatcgt aggagcttgt gcttttccga ttggtctaat tattatttta
     6421 atggcgggtg gagaattaat tacagggaac atgatggctg tttctgcagc tttgttggcc
     6481 aaaaaaatta agtttagcga gcttgccaag aattggctta tcattacctt gtttaatgtg
     6541 attggagctg tttttgtagc ttttgtgttt ggtcattttc taggtttgac atcagctggt
     6601 atttttaaag aagaagtgat tgaggtggcc catgctaaaa tagcagcgag ccctttgcag
     6661 gcactagtat caggaattgg ttgtaactgg tttgttggtt tggccttgtg gctatgctat
     6721 ggggcaaatg atgctgctgg taaattcctt ggtacttggt ttcctgtcat gacctttgta
     6781 gcccttggtt ttcagcatag tgtagcaaat gcttttgtca ttcctgctgc tatttttgaa
     6841 ggaggagcaa catggttgga ttttgccact aattttattt ttgtctatag tggtaatatt
     6901 atcggtggag ccatttttgt tagtttttta tattttaaag tgtactatca tccgcaaaag
     6961 agtaaaactc aatgagaaaa tattttttta gactgagggc gtcctattct cagtcttctt
     7021 tttataattt atggtaaaat aagaagcgaa gtttaaaaaa tttagctaaa taatggttag
     7081 tttattccct aaaaaaggag tattcccaaa aaatccgtaa aaagaatttg ctatgggagt
     7141 agttcccaaa ataatgcaga tcattagttg tctttcaaaa atagccttga tagggtaaaa
     7201 agtggacagt gatgcagcaa cagattcatc aggcgtacaa actatcttat ggtttgtgct
     7261 tagagatttc ttaataatgc ttttggtaat acacttttag tgaagaaagt gtagcatgaa
     7321 agtttaaaga taaccatgag tttgctttat gcactattgt tgagaaaata gcatagtcaa
     7381 ttgagtaaac atcatttctg catggaatga aacaattcct ataaacttat atcataagga
     7441 tggtttgcgg tttctaaaaa agtaacatga atcaaaaaac aaaagccaaa tatcccaagg
     7501 ccaaggtaac aagtcgagta aaaaagtttt tacttggcta atccaaacgg ttctgtcacg
     7561 attcacgcta aaattggaac tgctgagact tgtatcacag acaattcaga tcagacctta
     7621 gtaacttaca acttaaatgt agtagcttat aatacaaata acgaagataa tattgcggtt
     7681 gctgttatgt atccacatat tacgaatata tcggcaaaga tgtgagggcg ctttatgtgg
     7741 cgatatatgg aaaacaataa aggagaactt agtgctttat ccaacaccca ttgcaaagtt
     7801 aattgacagt tactctaaac ttccaggaat tggtatcaag acggcgacga gattagcctt
     7861 ttatactatt ggaatgtcaa atgaagatgt caatgatttt gctaaaaact tattagcagc
     7921 taaaagagaa ctgacctatt gttcgatttg tggaaacctt accgatgacg atccttgtca
     7981 catttgcaca gacacgagtc gtgatcagac gaccattctg gtagtagaag atgctaaaga
     8041 tgtttctgcc atggaaaaaa tccaagagta tcatggctat tatcatgtgc ttcacggctt
     8101 gatttcgcct atgaatggtg tggggccaga tgacatcaac cttaaaagtt taattacccg
     8161 tctaatggat ggtaaggtga gcgaagttat cgtagctacc aatgccacag cagatgggga
     8221 agcaacgtcc atgtatattt cacgtgtctt gaaaccagcc gggattaagg taactcgttt
     8281 ggcaagaggt ctcgcagtag gttcagatat tgagtatgct gatgaagtga cattattgag
     8341 agctattgag aatcgtactg aactttaatg atcatgttgg tgcctttact cgcaaagaga
     8401 ggttttgaaa aggctacatc tttttgttat aataaaaaaa cattcaattc agataagaaa
     8461 ggttagctat gtccaaacaa acgttagttc tattatacgg aggccgctca gcagaacgtg
     8521 aagtctcagt gctttcagca gagagtgtga tgcgagcagt caactatgat aagttcttag
     8581 taaaaactta ttttattact cagatgggcc aatttatcaa aactcagcaa ttttcagaaa
     8641 agccatcgga atcagaacgc ttgatgacaa atgagacgat agagctaact caaaaaataa
     8701 aaccaagtga tatctatgaa gaaggtgcag ttgtatttcc tgtattacat ggacctatgg
     8761 gagaagatgg ctctatccaa ggtttcttag aagtgcttag aatgccatat atagggacta
     8821 atgtcatgtc ttctagcata gctatggata aaattactac taaacgtgtc ttagaatcaa
     8881 ttggaattcc acaagttgcc tatactgttt atattgacgg acaagatttg gaggcttgtt
     8941 tagttgaaac tttagcaaga cttacttttc ctatcttcgt aaaaccagct aatatgggtt
     9001 cttctgtggg gatttccaaa gcccaaacaa aagtagaatt aagaaaagcg attcagttag
     9061 ccctgaccta tgacagtcgt gtcttgattg aacaaggcgt ggttgccaga gaaattgaag
     9121 ttggtctcct tggaaatgat aaggttaaat caactctacc aggagaagta atcaaggacg
     9181 ttgattttta cgactaccaa gcaaaatatg ttgacaataa gattacgatg gccattccag
     9241 cagatgtaga ccagagtatt gtgacagaaa tgcgttctta tgctgaagta gcctttaaag
     9301 ccttaggtgg ttgtgggttg tcccgttgtg actttttctt gacccaagac ggacaggttt
     9361 accttaacga attaaacacc atgccaggct ttacccaatg gtctatgtat ccactcttat
     9421 gggaaaatat gggattggct tatccagatt tgattgaaga gctggtgaca ctggcacaag
     9481 aaatgtttga ccagcgtgag agccacctga tttaaaccta tgagatgaat aaacattgac
     9541 ttggatggaa cggcaaacat cgtcaagatg tgacgttcgt cctttttttg ttgctcttta
     9601 tagtagagcc attaagggag tttgacattt tagaaatttt tctaatgttt tgtgctataa
     9661 tagataggac atcgtaaata ctagtgttct tagaaagaaa acaaaatgaa attaacctta
     9721 cacgaagtgg ctaaaatagt tgacgcccaa aataatgtgt ctgacttaga cgacgttcct
     9781 ctgcatcaca ttgaatttga tagccgaaag attacaaaag gagacctctt tttaccctta
     9841 aaaggtcaaa gggatggtca tgagtttatt gatttagcct ttcaaaatgg agctgtcgct
     9901 actttttcag aaaaagaatt gccggggaaa cctcaccttc ttgttgaaga ctgcctaaaa
     9961 gcttttcaaa agctagccca ttattatatt gataagatgc gcgtggatgt tattgctgtg
    10021 acaggctcaa atggtaaaac ttccaccaaa gatatgatag gagctgtcct atcaaccact
    10081 tacaaaactt acaaaacgca aggaaattac aataatgaga ttggtttgcc ttacaccgtt
    10141 ctccacatgc ctgacgatac ggaaaaaatt gttcttgaaa tgggacaaga tcacatggga
    10201 gatatttgtc ttctgtctga aattgcaagg cctcgtattg cagttttaac cttagtcggc
    10261 gaagctcatt tagaatattt tggaagccga gacaaaatag cccaaggcaa aatgcagatt
    10321 gttgacggca tgaattcaga tgggatttta attgctccgg gagatccgat tattgaccca
    10381 tatcttccag aaaatcagat ggttatccgt tttggaaatc agcaggaaat tgacgttact
    10441 ggtattcaag aagacaaaga tagcttaacg tttacaacaa atgtgttagc aacacctgtg
    10501 tccctacctc taccaggaaa atacaacgcg accaatgcta tggtagcagc ctatgtagga
    10561 aaactattgg cagtaacaga cgaggatatt atagctgctt tacagactgt gacgttgaca
    10621 ggtaatcgta cggagtggaa aaaagcagcc aatggtgctg atattttatc agatgtctac
    10681 aatgccaacc caacagccat gcgtctgatt ttagaaacat ttgctaacat agcaaagaac
    10741 cccggaggaa aaaagattgc agtgctagca gatatgaaag aacttggaaa ggattcagtg
    10801 atacttcatt ctcagttaat tgacagctta acatcaggta atattgatca gcttgttttt
    10861 tatggggatc atattaaaga attagcacgg ttggcaagtc aggtttatcc tgctgagcaa
    10921 gtacattatt ttttaaaaac tgaacaagaa gaccagtttg aagccatggc acaatatgtt
    10981 caaaacattc ttaatccctt tgatcaaatt cttttaaaag gcagccactc gatgtcgcta
    11041 gaaaagttag tagatcgatt agtgactgac aagaattgtg acagctatca gccttgattt
    11101 ttataaaact ttcagagaag ggcttgttct ctcatgaaga ttaaggtata atgaaaaaat
    11161 atagaaaggg acgattatgg atttttttgc aattgacccc atcggactgc ctcatatctc
    11221 acttatcttt tacttgttgt cactcttgat agcgcttttg cttgtttttt tgacttttca
    11281 agcatatagg ttaaaatctt atcgttattt tttcttgttt ttacagttat ctcaggtgat
    11341 tggcttgtac acatggtacg tgttaagggg gtttccttta gatgaagctt tgccgttgta
    11401 tcattgtcgc atcgctatgt tagctatctt ttttctacct gatcgtaaca agtttaagca
    11461 attatttatg gttttgggga taggtggaac attccttgca cttttatcgc cagatcttta
    11521 tccgtttaga ttatggcatg tagcaaatgt ctcgttttat cttggtcatt atgctttgtt
    11581 agtgaatggt ttgatttacc tcttgcgttt ttacgatgcc agtcagttaa gactgctatc
    11641 agtagtacgc tatttagcaa ctgttaactt tcttcttctg ttggtcagtt tagccacgaa
    11701 aggaaattat ggttttgtga tggatattcc agtgattcat acgcgtcatt tgctacttaa
    11761 ttttgtgatc gttacaagtg gcttgacttt tatggttaaa ataaccgaat atttttacct
    11821 taaatttggt gaagctcaac agctggcatt tgctttctct aaagaaaagt aggtcgttga
    11881 aaaagcactt aaaatcagct ataataagaa gagtctggga tgatttccag gctcgatttt
    11941 tttaaaaaag acactcattg atagcccaag ataagttata ataccagttt tgaagaactt
    12001 tagaggctaa tcgtatatgg agaaacccaa tgtagcccaa ctcttttgat aaacaaataa
    12061 tacctaacga aaataactca gagaaaagct ctgccatttt actatacaag gaaaaaagaa
    12121 tgtcacttac agaagaaatt aaaaaacgcc gtacttttgc catcatctct cacccggatg
    12181 ctggtaagac gactattact gagcaactat tatattttgg tggtgaaatt agagaagcag
    12241 ggacagtaaa agggaaaaaa tcaggtacgt ttgcaaagtc cgactggatg gatattgaaa
    12301 agcaacgtgg tatctctgtt acttcatctg ttatgcaatt cgattacgcg ggtaagcgtg
    12361 ttaatatttt ggatacacct ggacatgagg atttctcgga agatacatac cgtaccttaa
    12421 tggctgtgga tgcggctgtc atggttgtag attcggctaa aggtattgag gcgcaaacga
    12481 aaaaactttt tgaagttgtt aagcatcgta atattccggt ttttacgttt attaataaat
    12541 tggaccgtga tggacgtgag cctttagaac tcttggaaga attagaagaa gttttaggga
    12601 ttgcttctta tccgatgaac tggccgattg gtatgggacg cgcctttgag ggcttatatg
    12661 atttacataa taaacgttta gaactctata agggagacga gcgttttgca agtattgaag
    12721 acggtgatca gctgtttgcc aataatccct tttatgaaca agtcaaagaa gatattgaac
    12781 ttcttcaaga agcaggtaat gacttttcag aacaagctat tcttgatggt gacctaactc
    12841 cagtcttttt tggctctgcc cttacgaact ttggagttca gacttttctt gatactttct
    12901 tggagtttgc cccagaacct catggtcaca agactacaga aggtaatgtt gttgacccct
    12961 taactaaaga tttttcaggt tttgtcttta aaattcaagc taacatggac cctaaacacc
    13021 gtgaccgtat tgcttttgtg cgtattgttt ctggtgaatt tgagcgcggt atgggagtta
    13081 atttgacacg cactagcaaa ggcgctaagc tctccaatgt tactcaattt atggcagaat
    13141 cacgggaaaa tgtgacgaat gctgttgctg gggatattat cggggtttat gatacaggaa
    13201 cttatcaagt tggggatacc ttaacagttg ggaaaaataa atttgaattt gaacccttac
    13261 caacttttac cccagaaatc ttcatgaagg tttctccgaa aaatgttatg aagcagaaat
    13321 ccttccacaa aggtattgaa caattagtac aagaaggagc aattcagctt tataagaatt
    13381 atcagacagg cgaatacatg ctgggtgctg tgggtcaact gcagtttgaa gtctttaaac
    13441 atcgtatgga aggtgaatac aacgctgaag ttgtgatgac accaatgggt aaaaagactg
    13501 ttcgctggat ttcagaagat gatttggatc aacgcatgtc ctcaagccga aacattttag
    13561 ctaaggatcg ttttgaccaa ccagttttcc tatttgaaaa tgattttgcc cttcgctggt
    13621 ttgcagacaa atacccagat gtcactttag aagagaaaat gtaaccgaaa catgattttc
    13681 aacagtctaa cgttttggag atcaatttac tgagtaactt tttaaaagaa atgagtggct
    13741 agttatctct tttgcagatt taagattcta tcaaaaaacg atatcttcac aactgtaagc
    13801 atatttatga tttagcggat aatcgtgaaa gcgtgttatt gcttatatta gccttatttc
    13861 ctatcttttt gattctaatt gtgttacact agttaggttg ttaatcaaac gacgaaaatt
    13921 aaaaggttta taaggcagct tcgcactgcc tttttagaaa agagaaacaa ttgaaattta
    13981 cagaatttaa cttatcacaa gacatccaat cagctgttgt taccgctggt tttgagaaag
    14041 catctcctat ccaggaaatg acgattcctc tcgcactaga agggaaggat gttattggtc
    14101 aagcacaaac aggaactggt aaaacagcag cgtttggtct accaaccttg aataagattc
    14161 gtactaacga aaatatcatc caagcattgg ttattgcacc aacgcgtgaa ttggctgtac
    14221 aaagtcagga agaattgttc cgttttggac gtgaaaaagg ggttaaggtt cgctctgttt
    14281 acggtggatc aagtattgaa aaacaaatca aagcccttaa atcaggtgcc cacattgtcg
    14341 tgggaacacc gggtcgcttg ttagatttga ttaagcgtaa ggctcttatt ttagatcatg
    14401 tggaaacctt aatccttgat gaagcagatg aaatgcttaa catgggattc ttggaagaca
    14461 ttgaagctat tattagtcgt gtcccagcag accgtcaaac cttgctcttc tccgcaacga
    14521 tgccggcacc tattaaacaa atcggggtta aattcatgaa agaccctgaa catgttcaaa
    14581 ttaagaacaa agaattaaca aacgtcaatg ttgatcaata ctatgttcgt gtgaaagaac
    14641 aagaaaaatt tgatactatg acccgtctga tggatgttaa ccagccagaa ttatccatcg
    14701 tttttgggcg gactaagcgc cgagttgatg aaattacacg tggcttgaaa cttcgtggtt
    14761 tccgtgccga aggaatccat ggtgatcttg accaaaataa acgcttacgt gttatccgtg
    14821 atttcaaaaa cgaccaaatt gatattcttg ttgccactga tgtagcagcg cgtggccttg
    14881 atatttcagg agttacccac gtttataact acgatattac ccaagatcca gaaagttatg
    14941 ttcaccgtat tggtcgtaca ggtcgtgccg gtaaatctgg tgagtctatc acttttgtct
    15001 caccaaatga gatgggctac ctctcaatga ttgagaactt aacgaaaaaa cagatgaaac
    15061 ctcttcgccc agcaactgct gaagaggcct ttcaagccaa gaaaaaagta gccctcaaga
    15121 aaattgaacg cgactttgcg gatgagacta ttcgttcaaa ctttgataaa ttcaaaggcg
    15181 atgctgtcca attggctgcc gaattcactc ctgaagaatt agctttatat attttgagct
    15241 taacagttca agatccagat agcttaccgg aagttgaaat tgcacgtgaa aaaccattac
    15301 cattcaaata tgtgggtggt ggtcacggca ataaaaatgg caaaggtggt cgtggacgtg
    15361 acaaccgtaa ccgtggtgat cgccgtggcg gctatcgtgg tgaccgtaac agagatgagc
    15421 gtgatggtga ccgtcgtcgt caaaaacgtg ataagcgtga tggtcacgat ggcagtggca
    15481 accgcgattt caaacgtaaa tcaaaacgta atagtaaaga ctttttcaat aaagagaaaa
    15541 aatcaagtgc taaaaatact ggttttgtga ttcgtcacaa aggtgaataa gcttaaagag
    15601 agttgatgag agtcagctct ttttaatttt ctgaaaaagt tgcttttata atggaatctg
    15661 ttataatggt ttcagttatt ttgttataat ttttaaaaaa ttaggaggag tataagatgt
    15721 ctgatagcca tcttactgcc tttgacaaag cttcaaaagc aggttttatt attgctttag
    15781 gtattgttta tggagatatt ggaacaagcc ccctttatac gatgcagtct ctagttgaaa
    15841 atcaaggagg ggttaatcag gtttctgaat cctttatttt aggatcaatc tctttaatta
    15901 tttggacact gaccttaatc acaacaatca agtacgtttt gattgctcta aaagcggata
    15961 accaccatga aggtgggatt ttttctttat tcaccttggt acgtaaaatg tcaccgtggc
    16021 tcattattcc ggcgatgatt ggaggtgcaa cacttttgtc tgatggggct cttacacctg
    16081 cggtaacagt tacttcagct attgagggct tgaaagccgt tcctggtctg agtcacatct
    16141 accaaaatca aaccaatgtc attatcacaa ctctagtgat tttaatagtc ttgtttggta
    16201 ttcagcggtt tggaacaggt tttattggta aaatttttgg accagttatg tttatctggt
    16261 ttagttttct aggtgttagt ggttttttaa tatgttgggg catctggaaa ttttcaaggc
    16321 tatcaatcct tactatgctc tgcatttgct gtttagtcct gaaaaccatc gtgggatttt
    16381 tatcttgggg tccatttttc ttgcgacaac aggagctgaa gccctttatt cggatttagg
    16441 acatgttggt cgaggaaata tttatgtgag ctggcccttt gttaagatgt gtattgtgct
    16501 gtcttactgt ggccaggctg cgtggatttt agcgaataaa cactcaggta ttgaactaaa
    16561 ccctttcttt gctagtgtac cttcccaatt aacggtgtat gtggttattc ttgccacctt
    16621 agcagccatc attgcctcac aagccttaat ttcaggttct tttactttgg tttcagaagc
    16681 catgcgcttg aaaatattcc ctctatttcg agtgacttat cctggtgcta atttggggca
    16741 attgtatatt ccggtgatta actggattct ctttgcagtc acgtcctgta cggttttgta
    16801 ttttagaacc tctgctcata tggaagcagc ctatggcctg gccattacca ttaccatgtt
    16861 aatgaccact atattattga attactattt gattaaagaa ggtgtaaaac ctttcctagc
    16921 tcatttagtg atgactttct ttgcccttgt agaattcatt ttcttctggg cctccgctgt
    16981 caaattcatg cacggtggct atgtagtggt tattttagcg ctagcaattg tctttgtcat
    17041 gtttatttgg catgcgggca cacgcattgt tttcaagtat gtgaaatctc tcaatttgaa
    17101 tgattacaag gagcagatta agcaacttcg tgacgacgtt cgttttgacc tttaccaaac
    17161 caatgtggtt tatctctcca atcgcatgca ggatcacatg attgaccgtt ctattttgta
    17221 ttccatttta gataagcggc ccaagcgcgc tcaagtttat tggtttgtga atgttcaggt
    17281 aactgataag ccttatacag ccaagtataa ggtggatatg atgggaacag attatatggt
    17341 tcgagtcgaa ctttatctcg gttttagaat gccacagact gtgccacgct atttgcgtac
    17401 gattgttcat gacttgatgg aaagtggtcg tttgccaaag caagaacaag aatataccat
    17461 cacacctggc cgtgatgttg gtgattttcg ctttgtttta atagaagagc gggtctccaa
    17521 tgtacgtcaa ctcactaatg ttgaacgctt tattatgcag actaaagcga gcatcaaaca
    17581 tgtcactgcc agtccaatgc ggtggtttgg tcttcaatat tccgaagtaa cccttgaagt
    17641 ggttcccttg attctatcag atgtcttgaa gttaccaatc aaagaattgg tgcctgtgga
    17701 agacagtgaa gcataaaaaa atcattgaga tgataagtct caatgatttt tcttttcttt
    17761 ttgatgagta gcaatatagg ccaatttctg gcttcttgtt tttcgttttt taaagagtgc
    17821 ttcagcgctc atcgcagcct ctttgctatc aaacacttcg taataaagta aagaaacagg
    17881 taaccggtag cgagtatatt tagccccctt tcctgcgtta tgtgtagcta agcgtttttt
    17941 caaatcagtt gtataaccag tgtagagggt tttatctgca cattctaaca catacatata
    18001 agctttttta gtggtcatga ttaggttttc ctttggaagc agcaccaaaa taaatctcaa
    18061 aaatatgatc agtgtattct ccgttttcct tgtggacaac taaaggaggt aaaatagtca
    18121 tcccttcaat agaaccgtct ttgattgctt caataagtaa catattagct gatttaccta
    18181 atttaggata gacaaattgt acccttttag gggcaagacc attagctcta aggctatcta
    18241 taatttccaa gaatcgatct ggtcgatgaa ccattgccag acgaccattt gatttaaggg
    18301 catgacgggc tacctgacaa atctcttcta aattagtggt cacttcatga cgagccagta
    18361 aataatgttc agagacgttc ttcttagaac tttcgtgact tttaaagtaa gggggattgc
    18421 agagcatcaa atcaactcct gaacgtggca catggtttag gaggtttttt aaatcatcac
    18481 aaatcatggt tacttggtct tccagttgat tgagttggat agagcgttgt cccatatcag
    18541 caagccgttc ttgtaattct acttcaacga tggctgcctt ggttctagtg ctagcaaata
    18601 agccaaccgc cccatttcct gagcacaaat ccacaattaa ccctttggaa ggcatcttgg
    18661 ggaagcggga taagaggacg ctatcaatag agtaactaaa gacatccttg ttttgaataa
    18721 tgccaacatc acttgaaaag agttgatcaa tacgttcgcc ttcttttaag attgctttta
    18781 tcatacctgt tattttaaca taaaataggc ttgaggtgaa tgtttgaaga gtgattttga
    18841 ctttcgaaaa gtcaactttc atgatacaat aagtaagatt attctattaa aggagaagcc
    18901 tgtgttttac gcttacttac gcggtttagt agtcttttta ttatggattg tcaatggcaa
    18961 tgcccactac catcatgaag aaaagatgtt agatgcttct gagaattata ttctggtagc
    19021 accccatcga accttttggg atccagttta catggcattt gcagcacgtc ctaagcagtt
    19081 tatttttatg gctaaaaaag agttgtttgc aaatcgtctc tttgcttggt ggattaaaat
    19141 gtgtggtgct tttcctattg atcgtgacaa accgagtcca gatgctattc gttaccctgt
    19201 taatatgctc aaaaagagca atcgttctct tcttatgttt ccaagtggaa gtaggcattc
    19261 gcaagaggtc aaaggagggg tcgctgtgat tgctaaaatg gctaaggtca agattatgcc
    19321 agcagcctat caggggccta tgtcggttaa gggattacta gcgggagaac gggttgacat
    19381 gacttttggg aatcccattg acgtctcaga tattaaacgc atgaatgatg aagggattgc
    19441 tgaggtggca aaccgtattc aggcagagtt tgatcggatg gatgacgagt tggcaccttt
    19501 ccaaccaggc aaagcaagga accctttaac ttatctctac cgtttaccat taggattggt
    19561 tttggtggtg gtattattat taaccatgtt attttcctat attgctagtt ttgtttggaa
    19621 tccagataaa catcgccatt aagaacatga gggctaacat gtgtctgaaa taagaagtga
    19681 ttgagattag tcttctattg aaagaagccg ctaatgctta atcacttttt tcatttctaa
    19741 aaaagatatt cgatgatacc cttaactctt ttaagcacaa aaaatgacaa tactactata
    19801 cttttggata tcatttacga ataaaaagat gaggtaaaaa aatgttagac gaattattaa
    19861 ttaaaggaaa atcgtttttg agagagcggt attttctgcc atacctaatt agtcttttat
    19921 taggactttt tctaatacta agcttcagtt ttttgttctg gggaaatagg cagagcaagg
    19981 cagccgttcc tgctttgaga gaaatatcgc ctgtgaaaca gcaggttagt gaagaaaaaa
    20041 aggaaattca agaagatagc agtattttag tggatttaaa aggcgccgta caaaaagagg
    20101 gagtttataa gctaactgct agcagtcgtg tgcgagatgt cattgaacta gctggaggcc
    20161 taacttcaga agctgataaa catgctatta attttgcaga aaaactaact gatgagcaag
    20221 ttgtttatgt acctaaacaa ggagaagaga tttctgtgct accaagatca ttagtttctg
    20281 gtaaaaaaga aactgccagc aaggatcagt caaaggttca tattaataag gccagcttag
    20341 aagaactaca acatatccca ggtattggtg ctaaaagagc tcaggatatt attgatatga
    20401 gagataagtt aggtggtttt aaagcgttag aagatctccg tcaggtttcg gggattggcg
    20461 aaaaaacgct cgagaaatta aaagatgaca ttttcttgga ctaagctagt gcccctgtca
    20521 aagattcaat ttgctttttt aatcttggtt ttcttttatc aaatccatag ccctagctgg
    20581 ttaacgtttc tccttagcct tagtttgatt tgcttacttg tcaagcgttt gtctaaaaaa
    20641 gaatttctcg gtgtctttgc catccttagt ttctgtgctt tgtttttgct gtatcagaaa
    20701 cagcagttgg ttcaaaaact ggaaattcag ccagtacaaa taacctctgt agcattagtt
    20761 cctgatagta ttcggattaa tggtgatcaa ttagctgttc ttggacgtca tgggaaacat
    20821 tcttatcagt tattttaccg tttgaaaagc caagcagaag cccaattgtt caagaaagag
    20881 caccgttggt tagtgatgca cgcaaaagtg acattggaaa aagctgagga agttcgaaat
    20941 tttaaaggct ttaattatca gacttttttg gcttatcaag gaatttacag gatagggaag
    21001 gtagagcaaa tagaacagct tgaagtgatt tcacccgagt caatatgtga ctatttgtcc
    21061 tctttaagac ggcgagccat tgttcattgc cagcagcatt ttccaagacc tatgtctcac
    21121 tacctgacgg gcctcctttt tggttattta gataagtcgt ttggtgagat gacagattat
    21181 tatagtcagt tgggtatcat tcatctcttt gctttatcag ggatgcaggt tggcttcttt
    21241 ctcacttgtt ttagaagggt gttgctatta ctcgcagttc ctttggaatg gataaaatgg
    21301 atagagcttc cttttgcttc cttttatgcc gcgttgacag gttatagtat ttctgttatt
    21361 cgaagcctcg tgcagtcgca gttgcgtcat ttaggaataa aaggattaga caatctggct
    21421 tgtacttttt tacttgtctt tttatgggat gctcatttct taatgactgt tggtggcgta
    21481 ttaacgttta gctatgcttt tttgttaaca gtggttactg ttgaagaatt atcaggagct
    21541 aaaagacagt tggtacaagt cttgaccatt tccctaggaa tattaccatt tttgctcttt
    21601 tatttttcca gttttaaccc catgtcaatg gtcttaacag ggctcttgtc ttatctcttt
    21661 gaccttttta ttttgcccct tctttgtctg gttttttgtc tatccccttt ggtgactgtc
    21721 tcaatatgta accatctttt tattttatta gaaaaagtca ttcaatttct cggaaatact
    21781 ttcaatagtt cccttgtttt tggaagcccg accagttggc acttgcttat cttggtgatt
    21841 agcttcgcta ttttttatga ttatcggcag gtgcgacaac gagttatcac ttgcggtttg
    21901 gttatagcgt tgacgctttt gtctgtcaaa tatcctttga ccaatgaagt gacctttatc
    21961 gacattggcc agggagatag tattttggtg agggagtgga cagggaaaaa tctcttaata
    22021 gatgtaggtg ggcgcccttt cttttcttca aaagagcact ggcgacgaga atatcacgta
    22081 gctaatgctc agaaaacctt aattccttac ttaaaaagta gaggtattca cacaattgac
    22141 caactattag taactcacgc agatactgat catatggggg atatcgaagt ggttgccaaa
    22201 gctattcgga taaaggagat tttgactagt caaggcagtt taagccatcc aatctttgtt
    22261 aggcggctaa ggcgtttaaa atgtcacgtt agggttttag cagctggaga ccagttgcct
    22321 attatgggaa gtgtcttaca ggtactctac ccttggcagt taggggacgg gaaaaataac
    22381 gattctttgg tactttatgg caggctctta aatcgaactt ttcttttcac aggtgacttg
    22441 gaaaaagagg gggaaaacga gatcataaaa cgttatcctc aactaagagt agattattta
    22501 aaagcaggtc accatggatc aaatacctct tctagtgcag cttttttaga ccatattcag
    22561 cctaaagttg cctttatttc tgctggaaaa aataaccgtt atcagcatcc tcacagagaa
    22621 accttagccc gtttggaaga cagacaaatt acttattacc gaacggatac acaaggagct
    22681 attcgtttga ctggttggac aagctggcat cttgaaacgg tccgttagtt aaaatttcag
    22741 cctgacgaag aaacaagcag tcgctttcct tttaggagaa agatgatata ataaaagcat
    22801 gattgcgata gaaaagattg aaaaactgag taaagaaaat ttgggtctta taacccttgt
    22861 cacaggagat gacattggtc agtatagcca gttgaaatcc cgcttaatgg agcagattgc
    22921 ttttgataag gatgatttgg cctattctta ctttgatatg tctgaggccg cttatcagga
    22981 tgcagaaatg gatctagtga gcctaccctt ctttgctgag cagaaggtgg tcatttttga
    23041 ccatttgtta gatatcacga ccaataaaaa aagtttctta aaagaaaaag acctaaaggc
    23101 ctttgaagcc tatttagaaa atcccttaga gactactcga ctaattatct ttgctccagg
    23161 taaattggat agtaagagac ggcttgttaa gcttttgaaa cgtgatgccc ttgttttaga
    23221 agccaaccct ctgaaagaag cagagctaag aacttatttt caaaaataca gttatcaact
    23281 gggtttggga tttgagagtg gcgcttttga acaactgctt ttaaaatcaa acgatgattt
    23341 tagtcaaatc atgaaaaaca tggctttttt aaaagcctat aaaaaaacgg gaaatattag
    23401 cctaactgat attgagcaag ccattcctaa aagtttacaa gataatattt ttgacttaac
    23461 cagacttgtc ctaggaggta aagttgatgt ggctagagat ttgattcatg atttacgctt
    23521 atcaggggaa gatgatatta aattaattgc tattatgttg gggcaatttc gcttatattt
    23581 acagcttgcc attcttgcta aagaaggaaa atcagaacag cagcttgtaa ccagtttgtc
    23641 agagatactt ggtcggcggg ttaatcctta ccaggtcaag tatgcgttaa aggattctag
    23701 gaccttatct cttgcctttc taacaggagc ggtgaaaacc ttgattgaga cagattacca
    23761 gataaaaaca ggactttatg agaagagtta tctagttgat attgctctct taaaaatcat
    23821 gactcactct caaaaatagg cgttggaccg ctttccaaga gataatcaaa ttagttgaaa
    23881 gctcttattt tttgcgataa gatagacgta tcataaagga aaagaggaca ggaaaatggc
    23941 tattatttta ccagaacttc catacgcgta tgatgctctt gaaccacagt ttgatgcgga
    24001 gacaatgact cttcatcatg ataaacacca tgccacttat gtcgctaata ccaatgcggc
    24061 tttagaaaaa cacccagaga tcggagaaaa tctggaggaa ctattggcag atgtcactaa
    24121 gattccagaa gatattcgtc aagccttaat taataatggt ggcggacacc taaaccatgc
    24181 gcttttctgg gaactattat cacctgaaaa acaagacgtc actcctgatg ttgcacaagc
    24241 cattgatgat gcttttgggt catttgacgc ctttaaagaa caatttacag cagctgctac
    24301 tggacgtttt ggttcaggtt gggcatggtt agttgttaat aaagaaggac aactcgaaat
    24361 cacatcaacc gctaaccaag atactccaat ttcagaaggc aaaaaaccaa ttctagcgct
    24421 tgatgtgtgg gagcatgctt actacttgaa ttatcgtaat gtacgtccaa attatatcaa
    24481 agctttcttt gaaatcatta attggaaaaa agtatcagaa ctttaccaag ccgctaaata
    24541 agaaaagggt ttccaatctc aaaaagagat tggtttttta agtgcttttg tgaataacag
    24601 tgtggggaca tcatttttta gaaaagataa aaatagtttg tctttttaat gtaattcctt
    24661 gatttttagc taaatttagc tagaatagaa tggataggag gttttaggtg ttaagagaga
    24721 agaaaactac cattgtaggg attattttag gaatgatgat agtgacctta cttgtcggct
    24781 gtttgactgg taaaaagaaa ggctttcctc ctaaagcagg tgagcggcag caaacggctg
    24841 acttaaaaat gaaaagcaag attagaaaaa ctgttcaaaa accgttacct gaaaaatcta
    24901 aagaggctaa gcaagctgtt atggatgcag atttagcgta aatcgatgcc ttagggctct
    24961 attacgatga caaccatttg agtttggtca atacggtcaa ggcgtattta aaggaatttg
    25021 gcattggtga atcccaaatt gccttttcct acaaagacct caattcaggt aggactgctg
    25081 ccatgaatga ccatcagcca atgattgcag gaagcaccta taagctgcca ttaaacatgc
    25141 cggtggtaga taaggcaaat tatccatgac agagcgtttt gacattacag aaactgatta
    25201 tgaatatgat caggaacatc atgcctatgt tgctcaattc aatggtgcca tgtctattcc
    25261 ggatatgcaa gaatattcct tggtgtgctc agaaaacacg ccagcttatg ctctagcaga
    25321 acgattgggt ggcatgaata aggcttacca attatttgac cgctacggga aggtatccgg
    25381 ggctattacg accattgatc gtaatggcaa taaaatcacc accgcttact atttgcaagt
    25441 tttggattac ttgtggcagc atcaggataa atataaggat atcttgtact acattggtga
    25501 atctttccct gatttgtatt acaagactta tttgcctcat gtaaaggttt atcaaaaacc
    25561 gggttatgtc agagaagcct taaatgtagg tgccattgtt tgcgaagagt ctccttattt
    25621 gattgctctt tattcatctg gtttgggtgg agcaacacaa gcatcagagg aagtcaatgg
    25681 ccttggttat gtgcagcttg ttcagctaac atatgtaatt aatgagtggc atagagtcaa
    25741 tcacaacatg atctaatact cagttgacat tagtctgata gtagacatac ttactgatga
    25801 cagtcactaa aataagtttt tgctcattaa aaaagcttga cctgaagaaa caggtcaagc
    25861 tttttgagat taatgctgtg tttttgagat taatgctgtg tttttgagat taatgctgtg
    25921 tttttgaggt cttattgtca cctcttgttt cttgataatg gtgaatcaat tttttgaatt
    25981 ttttaacggc agcgcgtgtt agctgcttag atgatttgcc atttctgctg taaatgggat
    26041 tgtgcttatc cctttgctgt tctaaatcgg gaactagaaa agttgcatca ggactattaa
    26101 ttgctttttc aataaaagcc ggatcaaaaa gcagaatagg gtcaatatca agcagacggt
    26161 gcaagtcatc gttttggttg ccataattga aagaagaacc attgacaata ctatttcgcg
    26221 ttaggttatc aggatctagt gctactaaaa attgtccaga ttctgacaaa ataaactctg
    26281 agtgaaaatg aatcaaaatc ttatagttgg cttgaggaat attgtctgta tagactgcct
    26341 gatgattgcc attagcatct aaaatactag caaccttatt atggtatcta gaagattcat
    26401 aaagagcata atcgtcatct tctagagtag ccaaatattt ggctaaggca tccgcatcgg
    26461 ttttcccttt attcccataa tgtgagcgaa cccactccgt ttgctgggtt gatatgaggt
    26521 aacggagttg atgaattttc cgattaaaac ggctataagg aatgtgttcg agattaacat
    26581 aacaagcctg aatcagggca gataattggt cccaaaaagg atctgttggc gatagctttg
    26641 gacttaattg tgccaatact tgctgtgttt gttttgattg tcctgtcaac tcgtctggca
    26701 tctttaaata cgtcaagagc agctgtagcc gtttttgagc ttcttgaggc gtctgtgcca
    26761 tctcttcttg ttgccagagc ttttgaaagt caggtgatcc tatcaggcga atgcgactat
    26821 aaagttgttc gaaatgataa gagtttcctc taacagcgag ttgttcaagg tatccttttt
    26881 ggatggcttt ataggaccat ccgtccttat cgagttttcg aacataatca agcaagtcgt
    26941 ggcgtaattt aatagcttct gaaagctgga gctctcgtaa tttaggatag ttttggtaaa
    27001 aaggtgccac taaatcttga taaagtttgt gttctttttc aaaggcaatc cgctgatagt
    27061 ctttctgcca aaaactgacg caaaaagtca gaaacatcaa gaagaatagc cattttccaa
    27121 gtaatttcat aggtttttag ttgacaaaca tggcatcgcc aaagctaaag aaacgatact
    27181 tttcgtcaac cgcgtgtctg taagcttcaa ggacaaagtc acgccctgca aaggctgata
    27241 ctagcatcac aagggttgat tttggaagat ggaaattagt tgaaaaagca tcaactacgt
    27301 tgaattggta gcctggttta ataaaaatat tggtccaacc tgaatcagct tgaatgtccc
    27361 cttggaactt acttccgatg gtttccaacg tacgaataga ggtggttcct acagcgacaa
    27421 cacgaccgcc agcttgtttg acgtctctta gggtttgcgc tgcttcttct gagagggaat
    27481 aaaattccga atgcatatca tgctcatcga ggttatccac ggaaacaggt ctaaaagtcc
    27541 caagccctac atgtagggtc aaataaacca aatgtacccc tttggcttcg atttttttga
    27601 gcaagtctgt tgtgaagtgg agaccagcag ttggggcggc cgcagagcca ttttctttag
    27661 cataaacggt ttggtatcgc tcagcatcct ctaatttttc gtgaatataa ggaggcaatg
    27721 gcatttcgcc gaggctctct aaaacttcta agaaaatccc atcatagctg aattcaacaa
    27781 ttcgtccacc atgttctaat tcgtcgataa tggtggcttt gagacgccca tctccaaaat
    27841 tgacttggct accaaccttg agccgtttgg ctggcttggc taaaacttcc cattgatctc
    27901 cttgtgtatt tttaagcaaa agcaattcca catgaccatg agtatcgggt ttttctccat
    27961 aaagtctggc aggcaagaca cgggtgttat tcatgacgag ggcatcccct ggatttaatt
    28021 gatcaatgat atggtcaaaa tggctatcaa ccatagtttt ttgacggtga tcaataatca
    28081 atagttttga actgtctctt ttttcgagtg gggtttgggc aatcaattct tctggtaact
    28141 caaaatcaaa atcgttagta ttcattgggg ctcctttaaa gccactagta aatctcttcc
    28201 tagtaactct ttcatgtaag ataaatcttt tctattatat cacttgtcgt ctaacccgtc
    28261 atctttaatc tttcatcaga aagtaaagga taggcttgac aaaaattggt atataccata
    28321 taataaaaac acgaaaggtc tataccaatt agaaaaggag aatgacatga aaattattcg
    28381 ggtccaagat cagattgaag gtgggaaaat cgcttttacc ttattgaaag atagcttagc
    28441 taagggagct aagacgttag gattagcaac aggaagttca ccaattagtt tttaccaaga
    28501 aatggtcaaa agtcctttgg atttttcgga cttaacaagt attaacttgg atgaatatgt
    28561 cggtctttca gtagagagcg atcagagtta tgattatttt atgcgtcaaa acctttttaa
    28621 tgcgaagcct tttaaaaaga attacttgcc caatggttta gcaactgata tcgaagctga
    28681 agctaaacga tatgaccaaa tcattgcaga gcatccgatt gattttcaag tgcttgggat
    28741 tgggcgtaat gggcacattg gttttaacga acctgggacc tcttttgaag aagaaacgca
    28801 tgtggtggat cttcaagaat caaccattga agccaatagt cgtttcttta caagtattga
    28861 ggatgtgcca aaacaagcta tctctatggg aattgcctcc atcatgaagt ccaaaatgat
    28921 tgttcttctt gcctttggac aagaaaaagc tgatgcgatc aagggaatgg tttttggacc
    28981 aatcacagaa gacctcccag caagtattct ccaaaaacat gatcatgtta tcgtcattgt
    29041 ggatgaagct gctgcgtcac aattagacta acctaaccag tcgttaaacc ttgtaagaac
    29101 aaaaatgagg agatagtcaa cctcatttaa gaagaagtct tgtaacttct atttcttttg
    29161 caagggtaaa tttatgttac actactaata tgcgtttaga taaattatta gaaggtacaa
    29221 aagttggctc tagaagtcaa gtgaagaaac tgattaaggc tcaaggggtt tgggttgatc
    29281 acatgcctgc cagaaatggt cgacaaaatg ttgatcctgg cttacaactg attgaggtga
    29341 ctggacagcg agtgacgcat cctaaacatt cttacattat cctcaacaag ccatcagggg
    29401 tggtctcagc taagaaagat actaactatt taaccgttat tgatcagctt gctgaagaag
    29461 ataaaagtcc agacttgtat cctgttggca gattggatag agataccgaa gggttggttt
    29521 tactcactga taatggtccc ctagggtttc ggatgttgca ccctagtcat catgtttcta
    29581 aaacgtatct tgtaaccgtt aatggcttgt tagcagaaga tgcctcagat ttttttgcag
    29641 ctggtatttg tttcccaaca ggtgaacaat gccaaccagc tcaattgact attcttaaag
    29701 ccgatacaga ccagtcacag gctagtttga ccatttcaga aggaaaattt caccaagtga
    29761 aaaaaatgtt tttgacctat ggtttgaaag tgacctctct gaaacggacg cactttgcag
    29821 ggctggaact cggtcattta gccagcggag aatatcgtta tctaacagcg tcagaaaggc
    29881 aactcattaa aacgtatctg gactgagcaa aacatgcttt caaaaagaag ctattcttgc
    29941 ttaatcaata aagtgtccat tgactattat agtcatgatg agtccgactt ttgctatgtt
    30001 tagtcatctt gttgttacaa aatcagataa gcaaaaagat tcaattccca ctatctcctt
    30061 aacctgaagc gttataaaaa cccttgtgtt aaactctcat aaaattggaa atgggagtgt
    30121 tttttgatgg ctaaaaaaac taaagctact taaagtttgg tacttagttt tcgaataata
    30181 aggtggaaga tctaatagga ggtgacaaaa atattaaccg ctttagatgg taagaatcag
    30241 ctcatttcgc tagtaactca gcctatttca acgaaaccgc cttttcgttg cccagcttgc
    30301 aaatctcctg ttcgcttgcg tcaggggaca attagacgac ctcattttgc ccatgtacaa
    30361 ctagctcatt gtcaattcca agcagaaaat gaatctgagg aacatttgac gttgaaggca
    30421 aaactttaca ccagtttagt ccgaacagaa gctgtctgta ttgaaaaata tcttcctgag
    30481 ctgcaacaga tagcagacct ttgggtgaat gataagttag ccttagaaat tcagtgcagt
    30541 cccttgccag ttgagcgtct aaagaaacgc accaaagcct atcaagaaaa ggggtatccg
    30601 gtacgatggt tactgggaag aaaattgtgg cttaacactc acttaactgc tttgcaaaaa
    30661 cagtttcttt acttttcatc ttgtttgagc tttcatttgt gggagctgga tgcagctgca
    30721 aatctgctac gtctcaaata tttaatccat gaagacttat ttggtaaggt aagttaccta
    30781 accaaaacca tttctttaga ccacaatatt atggaaatgt ttcgattacc ctatcagcaa
    30841 gaaatccttt attcttatca gaaaaaaatg actgtgaacc tatctaaaag aatacaaaga
    30901 gctcttttag ctagacaccc gaaatggcta cgacgacaag aaaaggctta cttatcaggc
    30961 tataatttac ttatgttaac aactgatgct ttttatcctc aatggagacc agttcaatct
    31021 tccagcggtt tttgtcaaat taaaggaaat cttcgccctt attatgaaag ttttaaagtc
    31081 tattataaaa aagaaaagga taagaaggtg caaacgcttt tttcaccaaa atattatgtt
    31141 aaaatggata gtaatagaaa atgagaagga gatgttatga ctgataatcg cagccattta
    31201 gaagaaaaat acacttggga tttgagcact atttttgcaa cagataagga ttgggaagct
    31261 gaagtcagtg acttagctac tgaaattgac gcggctaagg atttttcagg tcatttacta
    31321 gattctagcg ctaatctgtt gacaattaca gatacttatt tagagttagc tcgtcgtgtt
    31381 gagaaagtct atgtttatgc tcacatgaaa aatgaccaag acactactgt tgccaagtat
    31441 caagaatacc aagctaaggc ttcaggcttg tatgcaaagt ttagcgaagt gttttcattc
    31501 tatgacccag aagttatggc attgagtcag gaagattacc aagcttttct tgcggaaaca
    31561 cctgatttaa aaaggtatca tcatttcttt gacaaattgt tccagacacg tgaccatgtg
    31621 ctcagccagg ctgaagagga attattagca ggagcccaag aaattttcaa cggcgctgaa
    31681 gaaaccttta gtattcttga taacgctgat attgtctttc cagtagttaa aaatgataag
    31741 ggggaagatg ttgaattaac ccatggtaac ttcattagcc taatggaatc taaggaccgt
    31801 agcattcgcc aagctgctta tgaagccatg tatagtactt atgaacagtt ccaacatact
    31861 tacgctaaaa ccttgcaaac caatgtgaaa gtgcaaaact ataaggcgcg tgttcataaa
    31921 tacgattcag cacgtcaagc tgccatggct gctaacttta ttccagaagc tgtttacgat
    31981 accttgttag aaacggttaa taaacatttg ccactcttac accgttattt gaaattgcgt
    32041 caagaggttc ttggtttaga cgatttgaag atgtatgatg tttacacacc attatctgaa
    32101 acagatttag ccattggtta tgatgaggct ttggaaaagg ctgagaaggt tttggctgtt
    32161 tttggtaagg attacgcgga tcgtgtacat cgtgctttta ccgaacgttg gattgatgtt
    32221 cacgtcaata aagggaagcg ctctggggct tattcaggtg gttcctatga taccaatgcc
    32281 ttcatgctgt tgaactggca agatacactt gataatcttt acacacttgt ccacgaaaca
    32341 ggccacagtt tgcattctac tttcactcgt gaaacacagc cttatgtgta tggggattat
    32401 agtatcttct tggcagaaat tgcatccaca acgaatgaaa acatcatgac agaagctctc
    32461 ttaaatgaag tgcaagatga gaaagaacgc tttgccattt taaaccatta cctcgatggt
    32521 ttccgtggaa cagttttccg tcaaacccaa tttgctgagt ttgaacatgc cattcatcaa
    32581 gctgatcaaa aaggagaagt gttaacaagt gaatacctta accagctata cgctgattta
    32641 aatgaaaaat attatggttt aagtaaaaaa gataatcatt ttattcagta tgaatgggca
    32701 cgtattcctc atttctatta caattattat gtttaccaat atgcaacagg gtttgcagct
    32761 gcaagctatt tagcggataa gattgtgcat ggcacacaag atgatatcga tcattacttg
    32821 gcctacctca agtcaggaaa ttctgattac ccacttgaag tgattgctaa agcaggcgtt
    32881 gatatggcaa aaggtgatta tttggaagct gcctttaaag tctttgacga acgtctaaca
    32941 gaacttgaag tactcgtgtc caaaggcata cacaaaagct aaaatcacaa aagtcaagga
    33001 caaaaagagt ttaggattga tagaaatgga gattcacagt tggtgtgaat ctccatttct
    33061 atcggtcatt ttctttttat attttagtgg attatcagtc ctgaaaagca ggcttcattg
    33121 accttagttt gacggtttct tttttgtctt ttttattgtg tggtcactca cttaaataaa
    33181 accaatagtt gagtaaggcg cttcagatta acgccattcc attgttttag agataacgtt
    33241 cgtataaaac atgtttttat tatatttgac attttataaa agagataata gaattaaaat
    33301 actaaccttt atgtttttta aaaaataaac gttcgtataa taaaaaagga gttttttatg
    33361 gaaaaaacaa aacgttatat cattgcaaca gcagggatac ttctccactt aatgttggga
    33421 tcgacctatg cttggagtgt ttatcgtaat ccaattttac aagagaccgg ttgggatcaa
    33481 gctcctgtcg cttttgcctt ttctttagct attttttgtt taggtttatc tgctgctttt
    33541 atgggaaatt tagttgaaca atatggtcct cgtctaaccg gaacggtgtc ggctattctt
    33601 tatgcttctg gaaatatgct gactggttta gcgattgatc gtaaagaaat ttggctttta
    33661 tatattggtt atggtgttat tggtggctta ggacttggag cgggatatat cacaccgata
    33721 tcaactatta taaaatggtt tccagataaa agaggcatgg caacagggtt tgctattatg
    33781 gggtttggtt ttgcgtcttt attaacaagt ccgattgccc agtggctaat tgaaacagaa
    33841 ggtttggtag caacatttta ccttttaggg ctgatttatc taatagttat gctttttgct
    33901 tctcaattga taataaaacc aactgctgct gagatagcta tactagataa aaaaagatta
    33961 caaaataaca gttatttaat cgaaggaatg accgctaaag aagcacttaa aacaaaatca
    34021 ttttattgtc tttgggtaat tttatttatc aatatcacat gtggcttagg acttatctca
    34081 gttgttgcgc caatggcaca agatctaact ggtatgagtc cagaaatgtc agcaattgtg
    34141 gttggtgcta tggggatttt taacggtttc ggtcgtttag tgtgggctag tttgtcagac
    34201 tatattggac gccgtgtgac agtaatactt ttatttttag taagcataat tatgactatt
    34261 agtttaatat ttgcacatag ttccctaatt ttcatgataa gcattgccac ccttatgact
    34321 tgttatggtg cgggtttttc tctcattccg ccttatttaa gtgatctttt tggggcaaag
    34381 gaactggcta cattacatgg gtatatattg acagcttggg caatagctgc attaactgga
    34441 cctatgttat tatctatcac tgttgaatgg actcataatt atcttcttac cttatgtgtt
    34501 tttattgtct tatacatttt aggattaatg gtagcattaa ggttaaagaa atgatgtcct
    34561 ataaaaaatt taaaagtaaa ccctagcaaa gcctagggtt tttttatata attaggttta
    34621 tggttaaatc atacagtaaa acagcaaatc ataatatgcg tcgtcctgtt gtcaaagaag
    34681 agcttgttca ttatatgcga acacggcaga agcaaaccac aggtttttta gcagagttag
    34741 agcaattcgc aagacaagaa aacattccta ttattcagcc tgaggtcgtg gcttatttca
    34801 ggtttttatt gcaaagctta cagccaaaac acattttgga gattggcaca gccattggtt
    34861 tttctgcgct tttaatggct gaaaatgcac cagatgcgac gattgtgact attgatcgta
    34921 atcgagagat gatcgatttt gctaaagcaa attttgctaa gtacgacagt cgccaacaga
    34981 tccgcctgtt agaaggagat gcagcagata tattatctac acttgaagga aattttgact
    35041 ttgtgtttat ggattccgcc aaatccaaat atattgtctt tctaccagag attttaagac
    35101 tgttaagagt cggtggtgta gtcattttgg atgatgtctt tcaaggaggt gacattacaa
    35161 aaccgatcga agacattcga cgaggtcagc gtactattta tcgtggctta cagtctttgt
    35221 ttgatgccac cttaactcat ccaaacctaa caactagcct ggtccctctt agtgatggat
    35281 tattaatgat tcgtaaaaat caagcagata ttgtattacc agattaagta acattgataa
    35341 atttatgtta taataaatta gttaaagata aaaaggagct cagaagtaaa tgaaaaactc
    35401 aaataaactc attgctagtg ttgtgacatt ggcctcagtg atggctttag cagcttgtca
    35461 atcaactaat gacaatacta aggttatttc gatgaaaggt gatacaatta gcgttagtga
    35521 tttttacaat gaaacaaaaa acacagaagt atcgcaaaaa gcgatgctaa atctggtaat
    35581 tagtcgtgtt tttgaagctc aatatggtga taaggtttca aaaaaagaag ttgaaaaggc
    35641 gtatcataaa acagctgaac agtatggcgc ttcattctct gctgctttgg cacaatcaag
    35701 cttgacacct gagactttta agcgtcagat ccgctcttca aaattagtag aatatgcggt
    35761 taaagaagca gctaaaaaag aattgacaac acaagaatat aagaaagcat atgaatctta
    35821 tactccaaca atggcagtcg aaatgattac tttagataat gaagagacag ctaaatcagt
    35881 cttagaggaa ctaaaagccg aaggcgcaga ctttacagct attgctaaag aaaaaacaac
    35941 aacacctgag aaaaaagtga cctataaatt tgattcaggc gcgacaaatg taccgactga
    36001 tgtcgtaaaa gcggcttcaa gtttgaatga gggtggaata tcagacgtta tctcggtttt
    36061 agatccaact tcttatcaaa agaagtttta cattgttaag gtgactaaaa aagcagaaaa
    36121 aaaatcagat tggcaagaat ataagaaacg tttgaaagct atcattatag ctgaaaaatc
    36181 aaaagatatg aatttccaaa acaaggttat tgcaaatgca ttggataaag ctaatgtaaa
    36241 aattaaagac aaagcttttg ctaatatttt ggcgcaatat gcaaatcttg gtcaaaaaac
    36301 taaagctgca agtgaaagtt caacaaccag cgaatcatca aaagctgcag aagagaaccc
    36361 atcagaatca gagcaaacac agacatcatc agctgaagaa ccaactgaga ctgaggctca
    36421 gacgcaagag ccagctgcac aataagtagg attttattga ctaatcagtt aaaaaaactt
    36481 ataataattt agttaagaat tgtttatcaa ggattagata cagaaaagtg acggttgctg
    36541 cgagtcattg ataattagat aaacatgcta cttaacttta caacaattga tatcgtaaat
    36601 taagaatgac aagttcattg aatagaggtg gtaccgcggt tttcgccctc tgtgagatgg
    36661 acttgttttg tattgaggac tatttgaaat caacgaaagg aatagagtag actaggctgc
    36721 caggcttata gctgatctcc tagcaagaaa gacgagctgt gtcaactggt gtgattacat
    36781 tactagcttc agcataacac tgtttttctt actctttgta tctaaatttt tatgaaagaa
    36841 ttatcgtctg cacaaatccg ccaaatgtgg ttggatttct ggaaatccaa aggacattgc
    36901 gttgagcctt cagctaactt ggttcctgtg aacgacccaa cgcttctttg gatcaactca
    36961 ggtgttgcaa ccttgaaaaa atattttgat ggttcagtga ttccagaaaa tccacgtatt
    37021 accaatgcac aaaaatcaat tcgtactaat gatattgaaa atgttggtaa aacagcacgt
    37081 caccatacta tgtttgaaat gcttggtaac ttctcaattg gagactattt ccgtaatgaa
    37141 gctattgagt ggggatttga actcttgaca agtccagact ggtttgattt ccctaaagac
    37201 aagctctaca tgacttatta cccagatgac aaggattcgt ataaccgttg gattgcttgt
    37261 ggcgttgaac caagtcactt ggtgccgatc gaggataact tctgggaaat cggtgctggt
    37321 ccttcaggtc cagatacgga gattttcttc gatcgtggtg aagatttcga tccagaaaat
    37381 atcggacttc gcctcttggc tgaagatatc gaaaacgatc gttacatcga aatctggaac
    37441 atcgttctct cacaattcaa tgctgaccca gccgtaccac gttcagaata caaagaatta
    37501 ccaaacaaaa acattgatac aggtgctggt cttgaacgtc ttgcagctgt tatgcaaggg
    37561 gcaaaaacaa actttgaaac tgaccttttc atgccaatca tccgtgaagt agagaagttg
    37621 tcaggtaaaa cttacgatcc agatggcgac aacatgagtt tcaaggttat cgctgaccac
    37681 atccgtgcgc tttcatttgc tatcggtgat ggtgcgcttc ctggaaatga aggtcgtggt
    37741 tacgttcttc gtcgtcttct ccgtcgtgcg gttatgcatg gccgccgtct tggcatcaac
    37801 gaaactttcc tttacaaatt ggttccgact gttggacaaa tcatggaaag ctactaccca
    37861 gaagtgcttg aaaaacgtga ttttatcgag aaaatcgtta aacgtgagga agaaacattt
    37921 gctcgtacta tcgatgcagg tagcggtcac ttagattcat tgcttgcgca gcttaaggct
    37981 gaaggtaagg atactcttga aggtaaagat atcttcaaac tttatgatac ttatggattc
    38041 ccggttgaat tgacagagga attggcagaa gatgcaggct acaagattga ccacgaaggc
    38101 tttaagtcag ccatgaaaga acaacaagac cgtgcgcgtg cagctgttgt taagggtggt
    38161 tcaatgggga tgcaaaatga aaccctagct ggtattgttg aagaatcacg attcgaatac
    38221 gacacatata gtcttgaatc aagtctttca gtcatcatcg ctgataatga acgtaccgaa
    38281 gctgtttcag aaggtcaagc tcttcttgtc tttgctcaaa caccattcta tgctgaaatg
    38341 ggtggacagg ttgctgacac aggtagaatc aaaaatgata agggtgacac agttgctgag
    38401 gttgttgatg ttcaaaaagc acctaatggt caacctctac acactgtaaa cgttttggca
    38461 tcactttcag ttggaacaaa ctacacactt gaaatcaaca aagagcggcg tttggctgtt
    38521 gagaaaaacc acacagctac tcacttgctc catgcagctc ttcacaatgt tattggtgaa
    38581 cacgcaactc aggctggttc attgaacgaa gaagaattct tgcgctttga ttttactcac
    38641 tttgaagcag taagcaatga ggaacttcgt cacattgaac aagaagttaa tgagcaaatt
    38701 tggaacgctc ttacaatcac aacgactgaa actgacgttg aaaccgcaaa agagatggga
    38761 gcaatggcac tttttggtga gaaatatggt aaagtggttc gtgtggttca aattggtaat
    38821 tattctgttg aactttgtgg tggaactcac ttaaataatt cttcagaaat cggtctcttc
    38881 aagattgtca aagaagaagg tattggttca ggcactcgtc gtattattgc agttactggt
    38941 agacaagctt ttgaagctta tcgtaaccaa gaggatgccc taaaagagat cgctgctact
    39001 gtaaaagctc cgcaattgaa agatgcagca gctaaagtac aagctcttag cgactcactt
    39061 cgtgatcttc aaaaagaaaa tgcagaactt aaagaaaaag cagcagctgc agcagctggt
    39121 gatgtcttta aagatgttca agaagctaag ggcgtgcgct tcattgctag tcaagttgat
    39181 gttgcagatg caggggcact tcgtacattt gctgataact ggaaacaaaa agactactct
    39241 gatgtgcttg ttctcgtagc agctattggt gagaaggtta atgtccttgt tgcaagcaaa
    39301 accaaagatg tccacgctgg taacatgatc aaagaattgg caccaattgt agcaggtcgt
    39361 ggtggaggta aaccagacat ggctatggca ggtggtagcg atgcaagtaa aattgcagag
    39421 ctgctagcag cagttgctga aacagtgtaa acccataaaa aaccaagtta tttagaactt
    39481 ggttttttat atttgaaatg actattatcg ttgtcaaaaa gaaaaagata tgttacaatg
    39541 atagtaacaa atagacatga ggaggtgtta gagaaaatga cacatggtat caaacttaag
    39601 aggcagattt gcttatgggc aagtatcctg actcttttca ttttaagtta tcatcttatc
    39661 agggtaatct ggtttggagt acccttgagt tatctggttt tgggctttac aggactagcc
    39721 ttgctgttga atactttttc ttattttaga aagtaagtta taagttaaag aagaatgaag
    39781 gagatggcaa tggaggttat tcttaaaaat cggctcaaag aattacgagc cagagatgga
    39841 attaatcaaa cggaaatggc taaactggca ggagtatcga ggcagaccat cagtctcatt
    39901 gagcgtaacg agtacacccc atcagttata attgccatga aaattgcaaa ggtatttcag
    39961 gaaccagttg aagaggtgtt tcgtctagtg gaggtcgagg aatgaaaaag aagaagaata
    40021 gttttttacg cttgttaaaa atgttattgc tatcaagttt ggcgggaggg attataggtg
    40081 gcatggttgg agccttttta ggttaccatg gagagagatt agatcagctc acgttcctaa
    40141 aagatgatgt gattaacctg attatcttat taaatcgtct agtagttgtc acaggcctca
    40201 cactttcttt tgttttttta acgcaactga aaaaagagac agctgtttat aacacaattg
    40261 aagaggatga ttattctgaa aatggttacc gtcagctgaa taaaaagcat gcttatacca
    40321 tgttattgat tgccgtagct tctattttat ccatgtgcaa tgtgctactt ggtctgacct
    40381 taactaatga ttcacagcat gccatgctgg ccattccgct tctggatatc cttttattat
    40441 taatggtcat tccttttcaa gctttagcca tgaaacgtta caatgccatt cggggaaccg
    40501 atgttcctta ttttccaaat ttgaaagaat taaaacataa tatcatggct ctagatgagg
    40561 cagagttaca agcctatcat aagacatcgt ttgaaagtgt gttttcatta aatggagtca
    40621 tcatcccttc cttgtatgtg attttatttt ttgtctatct attcactggt caagtggagt
    40681 taacagccat cttagttttg gtgttaattc agctctattt actcgttaag agtgcaacaa
    40741 tgaccagaca attttaccgt tagcctaaaa ggagactgtt tatgaaagga ttcattaatt
    40801 atttaaaaat agcagtgctc attattctgg ctatggtttt caatgtcctt ccgatgattt
    40861 tattgcaaaa gcaacacgat attcctatgg tacttaattg gggaattggt attttctact
    40921 tggttattgt tggaagtgtc cttattgtat tatggcgtct ttatcaagct aagcaagaca
    40981 cccctattaa acagcaaaaa atgagattgg ttgactgggg ttatttagca ttattttggt
    41041 taatcatccg tgtgatagct attgtaagta cccttgttaa ccagctatgg tctggtcaac
    41101 aagtgagtgc taatgatgct gcaatacata ccttagctag acttatcaaa ggtggtttcc
    41161 cgctttatac tgccctattt gtacttgtga tagcttttat cgctcctatt atggaagaac
    41221 tagtctttag aggatttcct atgattgatc tcttcaaagg aaaatcactt aaggtggcag
    41281 gtttagtgac ctctcttgtt tttgctttac cacatgccac caatagtgtt gaatttatca
    41341 tgtacagctg tatgggcatt tttctctttg ttgcctatca aagacgagga aacttaaaag
    41401 atgctatctt gttacatatt tttaataact tgattgaagt cattttgtta atgtcaatag
    41461 gcttaggagt catataataa aaagcttcgg atggatgaac tgcaccccaa aagttggaca
    41521 aaaaaactaa catttggttg gacttgtcaa gaaaaaatag acataaagtt aagctaatga
    41581 gtaactattt ttttcaaatt caacaggtga gagataccct aaagctgaat gcagacgttt
    41641 ggggttatag taagtctcac tatatttaaa aatctcaagc tgagcttgct caatagttgc
    41701 gaaatgagca tcattgacaa gctctctttt taatgtttta taaaaggatt ccatgagtgc
    41761 attatcgtat ggattacctt ttcgactcat cctggactta cattttttct gtctaagtag
    41821 gtcctgaaat tctgctccgg tatattgaga accctgatct gtatggacga ttaccccttc
    41881 tttaggcttt tctctattta taagcttgat tgaaagcttc tgttaccaac ttgtcttgca
    41941 tacgttagcc cattgcccaa ccaataacct ttttactata aacgtctata aagacagaaa
    42001 cataaagtat tccttcttgt gtaggaatgt aggttaggtc tcctagccat aatttattct
    42061 taccagtcgc ttggaaacat tgattaacaa gattgggacg agttaatgaa gaacgtcgac
    42121 ggttatagta tttatattga tatcgacttc ctttagcata gagacctagc tgatgaagga
    42181 gtctaccaac acgtttatga ttgacatgga tgccacgtct acaaagttct tgggtaattc
    42241 gtacgcttcc gtaacgctct ttatgttcat agaaaatggc tttaatcatt tccttcaaag
    42301 cttcattctc aacatgcctt gaagagggac gacgttttaa ataagcatag aaacctgaac
    42361 gggagacttg aagagtttga caggtgtgat gactattcaa gctaacacta ttttccttca
    42421 gaaactgaaa ttttatttcc ggtttggctt caagaagacc tggaactttt ttagaagagc
    42481 taattcctcc tgtagcagtt tgttctcttt ttcaagtttt tttatctcaa attgagcatg
    42541 acgaagtgcg ctcccatgtc ctgggaacgc actttctcca tatttttcat attcttgaat
    42601 ccatcgataa agactattgg gatgaatttc taaagttgaa ctaaccattt ttacaggctg
    42661 ctcttcctca aggatgagtt ttacagcaga gagtttgaag gctttatcaa aggtttttct
    42721 tggcataatg acttttcctc gtttccactt aattttgtgt ctactttagt ataccaagtc
    42781 caattcatcc gaagcttttt attaaaaaag taattaacta atcatttaag gatgaaacga
    42841 taaaactgat agctaaaata aaaaatgagg ttagctaatg ctaaagggat aatcattagt
    42901 aacgattggc ctgtaatttc aaccagaaaa actggtgccg ccaagggtat cttattgatc
    42961 acacctaaaa agattgttgc accaaccata atggctaacg tatttgatag agacaaggga
    43021 ataaggtact gactaaggat agctagtagt aagccactag cacctccaag catcatagaa
    43081 ggagcaattt tacccccttt tgctccagaa gcaaaaacta aagagatagc gacagctttg
    43141 gcaacaagta gccagctaat atagctcaga tgtggttctt catggagaaa aaagagtaat
    43201 ccagctttgc catttcctaa aatctctggg aagaaaatgc tgagtcctgc gataaggcta
    43261 aaagcgatga gaactttcgg aataaaccac tgacttttgg catcagcctt aggaaggtgt
    43321 tccaaaagat gtttgtaagc gtgagcaaag agggaaagga taagaccagc caggacggac
    43381 caaataaggg ttcctagcgt ccaatgttgc tgaggcatta ggtattgaat ctcatgtcgg
    43441 ccttgtaata aagcaactgt ttccacagcc acatagctcg ttaggcaggc agcgtatata
    43501 tttttaaggg accaacggtt aagaatagct tccaagataa ataaaatagt ggctaaggga
    43561 gcattgtaga cagcaccaag ggcagcgcta gaagcgcaag ctaataaaag tttttgatcg
    43621 gcttttgaca agttgcatct ttggctccaa agagacgtca aggtaacagc gacttcccgt
    43681 gaagctcctt ctcggccgac aggagctccc atagatacgg tcgttaattg gagccaacca
    43741 tgccaaaact gtgtccaggg actaaatgag atgtcatctt gaatgatttg ctgaatagat
    43801 tgaatgtcct ttcctttttt agccaatagg tgccacccaa gacctgcaag aagtccagca
    43861 aagagaagtg aaagagctcg tctttgtggt ggaacgctag caatcatagt gctaaaagaa
    43921 ccttgactga atccaaaact gagggactga atcaggtgaa tggcttttgt taagataaaa
    43981 gcaacaaggc cagctgttaa acctgttaaa aagaggtaaa aggtcaagag taaaaagtgt
    44041 cgtttcataa gactattata acaaaagtta agaaaagaga ctgatagatt atcagtctcg
    44101 tgagcactat tagagtccat aattataatc gtcatcagac atagcttcta cagaaccaag
    44161 aagatagcca ttccctacct gtgagaaaaa gtcatggttt gatgttcctg ttgaaatacc
    44221 attcataaca attgggttaa catcgtttgc agtatctggg aataaaggat cttgtcctaa
    44281 attcataaga gctttgttag cattgtagcg taaaaaggtc ataacttcct cagtccaccc
    44341 tacgccatca taaagcgttt tggtgtattt ttcttcattt tcatacagct gataaaggag
    44401 gtcatacatc caatcacgaa aattctcttg ctcatcttct ggtagttcgt taaaaccaag
    44461 ctggaatttg taaccgatat aagtaccatg tacagattca tcacgaataa ttagtttaat
    44521 gatttcagca acatttgcta gcttattatt tcccaaatag taaagagggg tgaaaaagcc
    44581 agaataaaaa aggaaagttt cgagatatgt tgaggcaact ttcttttgta aggcatctcc
    44641 attagcgtaa atgtcattga taatacgtgc tttttcttga agaaactcat tattattagt
    44701 ccactcaaag atctcttcaa tttctttttt ggtgtttaag gttgaaaaga tagacgaata
    44761 agatttagcg tgaacagatt ccatgaattg aatattgttt aagacagctt cttcgtgagg
    44821 agtgcgaaca tcagcacgaa tagcttcgac accagtttct gattgcatgg tatcaagtag
    44881 ggttaatcct ccaaaaacct tgccaacaag atctttttct tgaagagaaa gtttgcgcca
    44941 atcgtctaag tcatttgata aagggatacg ggtatcaagc caaaattgtt cggtcaactt
    45001 ttcccaagtt gacttgtcaa tgacgtcttc gatttcattc cagttaattg cttcataata
    45061 tgtagtcata gaaaaatgat ctcctaaaga gtagtaaagt gcgttaagga tatcgagata
    45121 aaccagtaga accgaccaaa gttctagtgg taataataag tttaaataga ttcaaaaggg
    45181 taacgaatga gttagtgagt ggtttaggca gatcgcctaa agcgactgcc gtagaagtaa
    45241 tagatgcttt agcatcatta gggcatatcg aggaattacg acacggagta aggaaagtcg
    45301 ataatacttt ccttacatag ttagtgagtg gtttaggcag atcgcctaaa gcgactgccg
    45361 tagaagtaat agatgcttta gcatcattac ttcttaacca attaaatgac acaagattca
    45421 cattggtttg cgcccacttc ttccccatca tccgtaaagg tacggatata gtagatagat
    45481 ttaatgcctt tattgaaagc gtagtttcgt aagatggata aatcacgagt ggtttgtttg
    45541 ctttgtgttt tccactcata aagctccata ggcaactcac tacgaaggaa tagagttaat
    45601 gacaagcctt ggtctacatg ttcggtcgca gcggcataga catcaataac tttgcgcatg
    45661 tccatatcgt aagcagatgt atagtaagga atggtatccg tagacaaacc atttgcagga
    45721 tagtagattt taccaatttt cttttcttga cgctcttcga tgcgttgtgt gattgggtga
    45781 atagaagcag agcagtcatt gatataagaa atagagccat ttggagcaac tgctagacgg
    45841 ttttgatgat aaagaccatc tttttgaacg gcgtcgcgaa gagctttcca atcctctgct
    45901 tgaggaataa agtgatcttt aaagagactt ttgaccaaat tagattttgg aacaaagtgt
    45961 cctgtaacgt atttatcaaa gtaactacca ttagcgtact tagagttctc aaagccaaca
    46021 aaggtagttt ggcgctcacg agcgatgtta ttggattcga ccaaggtcca ataattcagg
    46081 agcataaagt aaatatcagt aaactcgatg gattctggac tgccatattc aatatgatgt
    46141 tgagcaaggt aagaatgtag tcccatagct ccaaggccaa aagtatgagc ttggctattg
    46201 ccatgtttaa tggttggaac agcttcaatg cttgatgaat cagtaacaaa agttagggca
    46261 cgtgtcatgg tcttaataga acggccaaag tctggtgagg tcatcatgtt caggatatta
    46321 gtggaaccta agttacatga aatatcagtt cccatttcta caaactcttg cgcatcattg
    46381 ataaggctag gtgtttgaac ttgtaaaatt tcagaacaca agttgctcat gatgattttt
    46441 ccatcgatag gattagcttt attagctgta tcaatattga tgatataagg gtaaccagat
    46501 tcttgttgta attttgaaat ctctgtttca agatcacgag ctttaatttt agtcttagta
    46561 attttagggt tcgccactaa ctcatcgtac atattggtaa tgtcgagata gttaaaggga
    46621 atgccatatt ctttttcaac attgtaagga ctaaagagat acatgtcctc gtttttacga
    46681 gctaattcgt agaatttatc aggaacggta atccctagtg acaaggtttt aacacgcacc
    46741 ttttcatcgg cattttcttt tttagtagat aagaaagcaa tgatatcagg atgaaaaaca
    46801 tttaggtaaa caacaccagc tccttgacgt tgcccaagtt gatttgaata agaaaaacta
    46861 tcttcaaata atttcataac aggaacaact cctgaggctg caccagcata gcctttgatt
    46921 ggtgcgccag cttcacggag gttagacaag gtaatcccaa cacctccacc aatacgggat
    46981 aattgcaagg cagagttaat ggaacgtccg atagaattca tgtcatcagt tacttgaatc
    47041 aagaaacaag agaccaattc accacgacgg cttcgaccag catttaaaaa ggaaggagta
    47101 gccggttggt aacgttggtt aatcatttca acggctaaat cttttgctaa gtcttcttga
    47161 ccatctgcaa aatacaaagc attaaacaag acacggtctt caaggttttc taaataatgc
    47221 tctccatcat ttgtttttaa ggcgtattgc tggtagaact tgtaggctgc cataaatgat
    47281 ttaaagcgaa aattttctga tttgattatg ctatctaatt cagtaataaa ttcaggacgg
    47341 tatttctgaa taaaagctga ttcaatgtaa tcatttgaga ttaaatactc aattttttcc
    47401 gtaatggaag taaaagacat ggtgtttggc agcacatttt cagcgaaaaa agcttttaaa
    47461 gcttctttgt ctttatgaag tggaatttta ccattaacag gacggttaat ttcattattt
    47521 aggcgaaaat atgaaatatc gccaatatct ttgagactca tattattttt ccttgtctta
    47581 ttaaatcaat tcttttaact ttgcaggttg gaagccagaa aatacgaggt tatctgcttc
    47641 gataacagga gcagatgtga agccaagact tttcacataa tccacttttt caggatgttc
    47701 atcgatatta atttcctgga agttggctcc gtgttgttct aaaaatttct tagtcatttt
    47761 gcactgcatg caattatttt tggaatatac tgtaatcatg tcttgtcctt ctaaaattag
    47821 taatggttcc atcttaaatg gaattactat aatagcatat aaaaaataaa gctaaaaagc
    47881 aagctataaa cttatctaaa acacaacata ttgtgttgaa ataaaaaaca gaaacctaaa
    47941 tattgtgtca atctggattc ttatggttag agctctagcg ttttggtgat agaagctaag
    48001 cagttttaat aaagcattaa agtctgaaaa ataaattgtg aaaaacgtga aaataaaaga
    48061 aaataatttc acattttttg tcgtttaaat atttaatctt gaaaataaaa aagcattgtg
    48121 ctataatcgg ttgttgtaag ggttatcatg tgatggctca aaaatacaca acttaaaagg
    48181 agaaccatac tatggcttca aaagactttc acattgttgc agaaacaggt attcatgcgc
    48241 gtccagcgac tttgcttgtt caaacagcta gcaaatttgc ttcagacatc actcttgact
    48301 acaaaggtaa agcagtaaat ctaaaatcaa tcatgggtgt tatgagtctt ggtgttggtc
    48361 aaggtgcaga tgttactatc tcagctgaag gtgcagatgc tgaagatgcc attgcagcaa
    48421 ttgaagaaac aatgactaaa gagggattgg cataagacta tgacagaaat gcttaaagga
    48481 attgcagcct cagacggcgt tgctgttgct aaagcatatc tactagttca gccggatttg
    48541 tcatttgaga ctgttacagt cgcagataca aatgcagaag aagctcgcct tgatgttgca
    48601 ctccaagctg cacaagacga gctttctgtt atccgtgaaa atgcagtaga aagcttaggt
    48661 gaagaagcag cagccgtttt tgatgcccat ttgatggttc ttgctgatcc agaaatgatc
    48721 agccaggtta aagaaacgat tcgcgcaaaa caaacgaatg cagaaacagg tcttaaagaa
    48781 gtgactgaca tgttcatcac catctttgaa ggcatggaag ataacccata catgcaagaa
    48841 cgcgcagcgg acatccgcga cgttgcaaaa cgtgtgttgg ctcacctttt aggtgtaaaa
    48901 cttccaaatc cagctacaat caatgaagaa tcaatcgtta tcgcacacga tttgacacct
    48961 tcagatactg ctcaacttaa caaacaattt gtaaaagcat ttgttacaaa tatcggtggt
    49021 cgtacaagtc actcagctat catggcacgt acacttgaga tcgctgcggt acttggaaca
    49081 aatgatatta caaaacgtgt taaagatggt gatgtgattg ccgttaatgg tatcactggt
    49141 gaagtgatta tcgatccaag cgaagatcaa gtacttgctt ttaaagaagc tggtgcggct
    49201 tatgccaaac aaaaagcaga gtggtctctc cttaaagatg cgcatactga aacagctgat
    49261 ggcaaacact ttgaattggc tgctaatatc ggtacaccta aagacgttga aggtgttaat
    49321 gacaatggcg ctgaagctgt tggcctttac cgtactgagt tcttgtacat ggattctcaa
    49381 gacttcccaa ctgaagacga acaatacgaa gcttacaagg cagtgcttga aggcatgaat
    49441 ggcaaacctg ttgtggttcg tacgatggat attggtggcg acaaggaact tccttacttt
    49501 gaccttccaa aagaaatgaa tccattcctt ggtttccgtg ctcttcgtat ttccatctct
    49561 gaaactgggg atgccatgtt ccgcacacaa atgcgtgcgc ttcttcgtgc ctctgttcac
    49621 ggacaacttc gtattatgtt cccaatggtt gcccttctta aagaattccg tgctgcaaaa
    49681 gcagtctttg atgaagaaaa agcaaacttg cttgcagaag gcgttgcggt tgctgatgac
    49741 atccaagttg gtatcatgat tgagattcct gcagctgcta tgcttgcaga ccaatttgct
    49801 aaggaagttg atttcttctc aattggaaca aacgacctta tccaatacac tatggcagca
    49861 gaccgtatga acgaacaagt atcatacctt taccaaccat acaacccatc aatattacgt
    49921 ttgatcaaca atgtgatcaa agcagcgcac gctgaaggta aatgggcagg tatgtgtggt
    49981 gagatggcag gtgaccaaca agctgttcca cttcttgtcg gaatgggctt ggatgagttc
    50041 tctatgtcag caacttcagt acttcgtacg cgtagtttaa tgaagaaact tgactctgct
    50101 aagatggaag aatatgcaaa tcgtgcgctt acagaatgtt caacagcaga agaagttctt
    50161 gaactttcta aagaatacgt ttctgaagat taacgggtta aagagttggt ttaaaccagc
    50221 tcttttttgc tagctaaaaa tacaattact ttttggtgtg aaatcatttg agtcatcaaa
    50281 tgattatcag aattttcaga tatttagtgt agccaaatct tgaattatat cggaaaagtg
    50341 atagaataag attactatca taaaaggaga taaaacgttg gcaaaacaat ataaaaattt
    50401 agtgaacggt gaatggaaac tatcagaaaa cgagattacc atttacgcac cagcaacagg
    50461 tgaagagtta ggatcagttc cagcgatgac gcaggcagag gtagatgctg tttacgcttc
    50521 agctaaaaag gctctatcag attggcgcgc cttgtcttat gtggaacgtg cagcttacct
    50581 tcataaagcg gctgatattt tagtacgtga tgctgaaaag atcggcgcga ttctttcaaa
    50641 agaagtagcc aaaggtcaca aggcagctgt cagtgaagtt attcgtaccg ctgaaatcat
    50701 taattatgca gcagaagaag ggcttcgtat ggaaggtgaa gttcttgaag gtggtagctt
    50761 cgaagccgca agtaagaaga agattgctat tgttcgtcgt gaaccagttg gtttagttct
    50821 tgccatctca ccttttaatt atcccgttaa cttggcaggt tctaaaattg ctccagccct
    50881 tatttcagga aatgttgttg ctcttaaacc accaacacaa ggctctattt ctggtttgtt
    50941 actagcagaa gcttttgcag aagctggtat tccagcaggt gtctttaata ccattacagg
    51001 gcgaggttct gttattgggg attacatcgt tgagcacgaa gcggttaact ttatcaactt
    51061 tacaggttct actccaattg gggaaggaat cggtaaatta gcgggtatgc gaccaattat
    51121 gcttgagctt ggcggtaagg attctgctat cgttttggaa gatgcagatc ttgttttagc
    51181 agcgaaaaat attgtagccg gtgcttttgg ttactcagga caacgttgta cagcggttaa
    51241 acgcgttctt gtgatggaca aggtggcgga tcaattggcg gctgagatta aaacacttgt
    51301 tgaaaaacta agtgtcggaa tgcctgaaga cgatgctgat attacaccat taattgatac
    51361 atcagctgct gattttgttg aagggttgat taaagatgca actgataagg gagctactgc
    51421 tttgacagcc tttaatcgtg aaggcaatct tatttcaccc gttctctttg atcatgtgac
    51481 aactgacatg cgtttggcat gggaagagcc gttcggccca gtattaccaa ttattcgtgt
    51541 aaccactgta gaagaagcca tcaagatttc taatgagtct gaatatggtt tgcaagcttc
    51601 tatttttaca actaatttcc caaaagcttt tggcattgct gagcaattag aagttggaac
    51661 tgttcacctt aacaataaaa cacaacgtgg aacagataat ttcccattct taggcgctaa
    51721 aaaatcaggt gcaggggtac aaggagttaa atattctatc gaagctatga caactgttaa
    51781 atctgttgta tttgatatcc agtaataaaa aaaataaaca aaaagttagg ttaacttaac
    51841 tttttgttta tttttttaat gttttttgtt acaatagtct atacagatgg aggcaactat
    51901 tgaaaaaatt aaatgttatt cttgttggtt tattaagcat tctgattttg agtttagcta
    51961 ttgtgtttat taatcgttgg aaactaaacg aagatagtca gcgtatagtt ttggctgaaa
    52021 agaaaaaaaa cacgtcagat t
//
LOCUS       DAUGOH010000012        46195 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUGOH010000012 DAUGOH010000000
VERSION     DAUGOH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46195
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.012"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            18..98
                     /locus_tag="VH957_000700"
     tRNA            18..98
                     /locus_tag="VH957_000700"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VH957_000701"
     tRNA            105..175
                     /locus_tag="VH957_000701"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VH957_000702"
     tRNA            187..259
                     /locus_tag="VH957_000702"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VH957_000703"
     tRNA            268..339
                     /locus_tag="VH957_000703"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VH957_000704"
     tRNA            359..442
                     /locus_tag="VH957_000704"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            1525..1833
                     /locus_tag="VH957_000705"
     CDS             1525..1833
                     /locus_tag="VH957_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ8558634.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSDVPYCLLSGCAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            1888..2100
                     /locus_tag="VH957_000706"
     CDS             1888..2100
                     /locus_tag="VH957_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ8558635.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATALMIGSGKTVFALCQTEKQTIIV"
     gene            2210..2653
                     /locus_tag="VH957_000707"
     CDS             2210..2653
                     /locus_tag="VH957_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEQ8558636.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2657..3376
                     /locus_tag="VH957_000708"
     CDS             2657..3376
                     /locus_tag="VH957_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558637.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRRLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEVETDDEKGGHGHA"
     gene            3369..4184
                     /locus_tag="VH957_000709"
     CDS             3369..4184
                     /locus_tag="VH957_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8558638.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVIGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4224..4607)
                     /locus_tag="VH957_000710"
     CDS             complement(4224..4607)
                     /locus_tag="VH957_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8558639.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWEGITINQENWDLAPFLKHL"
     gene            complement(4658..5914)
                     /locus_tag="VH957_000711"
     CDS             complement(4658..5914)
                     /locus_tag="VH957_000711"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEQ8558640.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHSEEVYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6006..8318
                     /locus_tag="VH957_000712"
     CDS             6006..8318
                     /locus_tag="VH957_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8558641.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQKHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEISVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8582..12148
                     /gene="rpoB"
                     /locus_tag="VH957_000713"
     CDS             8582..12148
                     /gene="rpoB"
                     /locus_tag="VH957_000713"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8558642.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12239..15880
                     /gene="rpoC"
                     /locus_tag="VH957_000714"
     CDS             12239..15880
                     /gene="rpoC"
                     /locus_tag="VH957_000714"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEQ8558643.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTADKYFLEPGQDIQEVIDGLEINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16032..16397
                     /locus_tag="VH957_000715"
     CDS             16032..16397
                     /locus_tag="VH957_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEQ8558644.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16490..17428
                     /gene="tadA"
                     /locus_tag="VH957_000716"
     CDS             16490..17428
                     /gene="tadA"
                     /locus_tag="VH957_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEQ8558645.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGHES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17412..18398
                     /locus_tag="VH957_000717"
     CDS             17412..18398
                     /locus_tag="VH957_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEQ8558646.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFTEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMAILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18400..18726
                     /locus_tag="VH957_000718"
     CDS             18400..18726
                     /locus_tag="VH957_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEQ8558647.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18701..19129
                     /locus_tag="VH957_000719"
     CDS             18701..19129
                     /locus_tag="VH957_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEQ8558648.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19134..19370
                     /locus_tag="VH957_000720"
     CDS             19134..19370
                     /locus_tag="VH957_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8558649.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEITLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19363..19797
                     /locus_tag="VH957_000721"
     CDS             19363..19797
                     /locus_tag="VH957_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEQ8558650.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRNHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19781..20107
                     /locus_tag="VH957_000722"
     CDS             19781..20107
                     /locus_tag="VH957_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8558651.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVSFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20205..21158
                     /locus_tag="VH957_000723"
     CDS             20205..21158
                     /locus_tag="VH957_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8558652.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21217..22413
                     /locus_tag="VH957_000724"
     CDS             21217..22413
                     /locus_tag="VH957_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEQ8558653.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22600..22908
                     /locus_tag="VH957_000725"
                     /pseudo
     CDS             22600..22908
                     /locus_tag="VH957_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22991..23761)
                     /locus_tag="VH957_000726"
     CDS             complement(22991..23761)
                     /locus_tag="VH957_000726"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEQ8558654.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23809..24876)
                     /gene="pepA"
                     /locus_tag="VH957_000727"
     CDS             complement(23809..24876)
                     /gene="pepA"
                     /locus_tag="VH957_000727"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEQ8558655.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPNIEDIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEDAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            25332..25625
                     /locus_tag="VH957_000728"
     CDS             25332..25625
                     /locus_tag="VH957_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEQ8558656.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25622..25939
                     /locus_tag="VH957_000729"
     CDS             25622..25939
                     /locus_tag="VH957_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEQ8558657.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25957..26583
                     /locus_tag="VH957_000730"
     CDS             25957..26583
                     /locus_tag="VH957_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEQ8558658.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPIVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            26735..27130
                     /locus_tag="VH957_000731"
     CDS             26735..27130
                     /locus_tag="VH957_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8558659.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27384..28025)
                     /locus_tag="VH957_000732"
     CDS             complement(27384..28025)
                     /locus_tag="VH957_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEQ8558660.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYEVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28045..29022)
                     /gene="dusB"
                     /locus_tag="VH957_000733"
     CDS             complement(28045..29022)
                     /gene="dusB"
                     /locus_tag="VH957_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEQ8558661.1"
                     /translation="MIKLNSSFRIGDVEIPRRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(29009..29881)
                     /gene="hslO"
                     /locus_tag="VH957_000734"
     CDS             complement(29009..29881)
                     /gene="hslO"
                     /locus_tag="VH957_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEQ8558662.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISYLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIINDKA"
     gene            complement(30028..31521)
                     /gene="rofA"
                     /locus_tag="VH957_000735"
     CDS             complement(30028..31521)
                     /gene="rofA"
                     /locus_tag="VH957_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEQ8558663.1"
                     /translation="MIEKYLESSIESKCQLIVLFFKTSYLSITEAAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALVPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFISPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSINFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVQHELTKGIAVAEISFDESILSIQELIYQVKEEKFQADLTKQLT"
     gene            31753..33498
                     /gene="sfbI"
                     /locus_tag="VH957_000736"
     CDS             31753..33498
                     /gene="sfbI"
                     /locus_tag="VH957_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein SfbI"
                     /protein_id="HEQ8558664.1"
                     /translation="MVSSYMFVRGEKMNNKMFLNKEAGFLAHTKRKRRFAVTLVGVFF
                     MLLACAGAIRFGQVAYAADERTVPNFKSPDPDYPWYGYDAYTGAFLRYHDLRVNLNGS
                     RSYQVYCFNIKKNYPRPFTSSDKKWYKRLEGTAETFKVHAMAPRVGGEELTKKLRSVM
                     YNGYPNDGNNIMKGLEPSNAIEVTQYAVWYYSDKSQYEIETLWKSEAKEGKISESQVT
                     LMREALRKLISSDEDLVKQVPSNFKLSTFESSDKSYQNLLSAEFVPDDPPKPGDTSEH
                     NPKTPELDGSPIPEDPKHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALPPLMPELDG
                     EEVPEKPSVDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQNPVDIDKKLPNE
                     TGFSGNMVETENTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVETEDTKEPGVLMG
                     GQSESVEFTKDTQTGMSGQTAPQVETEDTKEPGVLMGGQSESVEFTKDTQTGMSGFSE
                     TVTIVEDTRPKLVFHFDNNEPKVEENREKPTKNITPILPATGDIGNVLAFLGILILSV
                     LSIFSLLKNKQNNKV"
     gene            33786..34634
                     /locus_tag="VH957_000737"
     CDS             33786..34634
                     /locus_tag="VH957_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEQ8558665.1"
                     /translation="MTERLKNLGILLLFLLGTAIFLYPTLSSQWNAYRDRQLLSTYHK
                     QVTQKKPSEMEEVWQKAKAYNARLGIQPVPDVFSFRDGIHDKNYESLLQIENNDIMGY
                     VEVPSIKVTLPIYHYTTDEVLTKGAGHLVGSALPVGGDGTHTVISAHRGLPSAEMFTN
                     LNLVKRGDTFYFRVLNKVLAYKVDQILTVEPDQVTSLSEVMGKDYATLVTCTQYGVNT
                     KRLLVRGHRIAFHYKKYQQAKKAMKLVDKSRMWTEVVCAAFGVVIAIILVFMYSKMTD
                     KKVIKN"
     gene            34920..37181
                     /locus_tag="VH957_000738"
     CDS             34920..37181
                     /locus_tag="VH957_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus ancillary protein 1"
                     /protein_id="HEQ8558666.1"
                     /translation="MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMLLVLIGFEGKV
                     RAAHELVEVPVPIFHNPDPQSDYQWYGYEAYTGGYPKYDLFKTYYHDLRVNLHGSKSY
                     QVYCFNVHKHYPRPSQSFDRKWYKKLDGTAENFDSLAMEPRVRKEELTKKLRAVMYNA
                     YPNDANGIMKDLEPLNAIKVTQEAVWYYSDNSPINPDESFKSEALANKISATQISLMR
                     EALKQLIAPDLDEKQSRRVPDGYQLSIFESENKDYQNLLAAEEVPIQPPKPGDKPPLP
                     PVQTKQTSVIIRKYAEGDYSKLLEGATLKLAQIEGSGFQEKIFDSNKSGEKVELPNGT
                     YVLSELKPPQGYGVATPITFKVAAGKVLIKNKEGQFVENQNKEIAEPYSVTAFNDFEE
                     IGYLSDFNNYGKFYYAKNTNGTNQVVYCFNADLHSPPDSYDHGANIDPDVSESKEIKY
                     THVSGYDLYKYAVTPRDKDADLFLKHIKKILDKGYKKKGDTYKTLTEAQFRAATQLAI
                     YYYTDSADLTTLKTYNDNKGYHGFDKLDDATLAVVHELITYAEDVTLPMTQNLDFFVP
                     NSSRYQALIGTQYHPNELIDVISMEDKQAPIIPITHKLTISKTVTGTIADKKKEFNFE
                     IHLKSSDGQAISGTYPTNSGELTVTDGKATFTLKDGESLIVEGLPSGYSYEITETGAS
                     DYEVSVNGQNVPDGKVMKELVKEDETVAFENRKDLVPPTGLTTDGAIYLWLLLLVPFG
                     LLVWLFGRKGTKK"
     gene            37178..37699
                     /gene="lepB"
                     /locus_tag="VH957_000739"
     CDS             37178..37699
                     /gene="lepB"
                     /locus_tag="VH957_000739"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8558667.1"
                     /translation="MTNYLNRLNENPLFKAFIRLVLKISIIGFLGYILFQYIFGVMII
                     NTNDMSPALSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVSFTQEGG
                     LLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALPINQI
                     KGKISTLLRVRGI"
     gene            37721..38770
                     /locus_tag="VH957_000740"
     CDS             37721..38770
                     /locus_tag="VH957_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QVPTGV class sortase B protein-sorting
                     domain-containing protein"
                     /protein_id="HEQ8558668.1"
                     /translation="MKKNKLLLATAILATALGTASLNQNVKAETAGVVSSGQLTIKKS
                     ITNFNDDTLLMPKATFTFDVKPVDVTGEEKDTASGLKIQKGIAGVASQTIQYDNTDKP
                     TNKEKAVNFDFSTVTFPNVGVYRYEVSEQAGDVKGITYDSKKWTVDVYVVNENNKFTP
                     KYIVSKETTDSSKKPIVFNNELKTTSLTIKKEVTGNSGDKTSDFTFTLLLKENTQFET
                     GQKVKATKKKSGAEEETVEVTIGKQYTFTLKDSEELILDKLPIGITYQVDETDKNKEQ
                     YETSAKMTEDSKEAQGYTLNDLKTTDETADTITVTNKRNLPIPTGVVGILAPFAVLSI
                     VAIGGVIYITKRKKA"
     gene            38786..39511
                     /gene="srtB"
                     /locus_tag="VH957_000741"
     CDS             38786..39511
                     /gene="srtB"
                     /locus_tag="VH957_000741"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HEQ8558669.1"
                     /translation="MMMTIVQVINKAIDTLILIFCLVVLFLAGFGLWDSYHLYQQADA
                     SNFKKFKTAQQQPKFEDLLALNEDVIGWLNIPGTHIDYPLVQGKTNLEYINKAVDGSV
                     AMSGSLFLDTRNHNDFTDDYSLIYGHHMAGNAMFGEIPKFLKKDFFNKHNKAIIETKE
                     RKKLTVTIFACLKTDAFDQLVFNPNAITNQDQQRQLVDYISKRSKQFKPVKLKHHTKF
                     VAFSTCENFSTDNRVIVVGTIQE"
     gene            39528..40115
                     /locus_tag="VH957_000742"
     CDS             39528..40115
                     /locus_tag="VH957_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HEQ8558670.1"
                     /translation="MRKYWKMLFSVVMILTMLAFNQTVLAKDSTVQTSISVENVLERA
                     GDSTPFSVALESIDAMKTIEEITIAGSGKASFSSLTFTTVGQYTYRVYQKPSQNKDYQ
                     ADTTVFDVLVYVTYDEDGTLVAKVISRRAGDEEKSAITFKPKRLVKPIPPRQPDIPKT
                     PLPLAGEVKSLLGILSIVLLGLLVLLYVKKLKSKL"
     gene            complement(40274..41479)
                     /locus_tag="VH957_000743"
     CDS             complement(40274..41479)
                     /locus_tag="VH957_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEQ8558671.1"
                     /translation="MVIFDLKHVQTLHSLSQLPISVMSQDKALIQVYGNDDYLLCYYQ
                     FLKHLAIPQATQDVIFYEGLFEESFMIFPLCHYIIAIGPFYPYSLNKDYQEQLANNFL
                     KHSSHRSKEELLSYMALVPHFPINNVRNLLIAIDAFFDTQFETTCQQTIHQLLQHSKQ
                     MTADPDIIHRLKHISKASSQLPPVLEHLNHIMDLVKLGNPQLLKQEINRIPLSSITSS
                     SISALRAEKNLTVIYLTRLLEFSFVENTDVAKHYSLVKYYMALNEEASDLLKVLRIRC
                     AAIIHFSESLTNKSISDKRQMYNSVLHYVDSHLYSKLKVSDIAKRLYVSESHLRSVFK
                     KYSNISLQHYILSTKIKEAQLLLKRGIPVGEVAKSLYFYDTTHFHKIFKKYTGISSKD
                     YLAKYRDNI"
     gene            41870..45247
                     /locus_tag="VH957_000744"
     CDS             41870..45247
                     /locus_tag="VH957_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEQ8558672.1"
                     /translation="MTQKNSYKLSFLLSLTGFILGLLLVFIGLSGVSVGHAETRNGAN
                     KQGSFEIKKVDQNNKPLPGATFSLTPKDGKGKPGQTFTSNDKGIVDAQNLQPGTYTLK
                     EETAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISKAGSKDVSSSLQLEKSTMSV
                     VSKYGEQEKTSNLADFYRNHAAYFKMSFELKQKDKSETINPGDTFVLQLDQRLNPKGI
                     SQDIPKIIYDSANSPLAIGKYDADSHQLIYTFTDYIAGLDKVRLSAELSLFLENKEVL
                     ENTNISDFKSTIGGQEITYKGTVNVIYGNKSGDSNNYVKNILSNVGGSIESYNTQTGD
                     FTWYVYVNPKKQSINYSILNLWGFGRARSNTNNLETNANTSSAQLEKVEIYEVKEDYT
                     LPTSYGVDITKLTLRTDITVGNKDGFPMTKRQRIDFKDNLKDGKRFVVKVTGKTDQSG
                     KPLVVQSNLASFSTNQDYVDLKISGGNVYFQNEIALSPSKGSGSGKSEFTKPSITVAN
                     LKRVAQLRFKKMSTDNVPLPEATFELRSSTSDSQKVEAKSNEQGEVHFKDLNSGTYDL
                     YEKQAPKGYQQVTEKLATVTVDTTKPAEEMVKWEKTHPFVKVEVNKEVTIVNHKETLT
                     FSGKKIWENDRPDQRPAKIQVQLLQNRQKMSDKVQEVTKDNDWSYHFKDLPKYDDKNQ
                     EYKYSVEEVKVPDGYKVSYLRNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGSKIID
                     EDTLTSFKGKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEFKNLK
                     KYNGTGNDIMYSVKEVTVPTGYDVTYSANDIINTKREVITQQGPNLEIEEMLPLESGA
                     SGGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFSKRDIDGKELAGATMEL
                     RDSSGKTISTWISDGQVKDFYLMPGKYTFVETAAPDGYEIATAITFTVNEQGQVTVNG
                     KATKGDAHIVMVDAYKPTKGSGQVIDIEEKLPDEQGHSGSTTEIEDSKSSDVIIGGQG
                     QIVETTEDTQTGMHGDSGCKTEVEDTKLVQSFHFDNKESESNSEIPKKDKPKSNTSLP
                     ATGEKQHNMFFWMVTSCSLISSVFVISLKTKKRLSSC"
     gene            complement(45513..46178)
                     /locus_tag="VH957_000745"
     CDS             complement(45513..46178)
                     /locus_tag="VH957_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558673.1"
                     /translation="MKRCNKYLFTSLLAVSILFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKTLVDNNNSIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPKEITYEHHY
                     WDGTVDSKTRSNTQWHYDWENQKTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEEGYKDKWNKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
BASE COUNT        14477 a         8069 c         9778 g        13871 t
ORIGIN      
        1 aaaatttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tgtaaacctt gttttttgtt
      481 ttgatcttaa gctgtagcta cgtagtacaa tctcttatat tactgataag gtctatttaa
      541 tgcgcaagat ttgtggtatg atgaatatga ttgagtattg atgctttatg ggattaccgg
      601 taaggttttg aaaaaggttt gtcactacta ggtgcttttt tagctataga aagacagtta
      661 tggattgatg tattgtaact aatgttggag gttaatggtg gttgagtttt gagatattta
      721 cactgataat cgggtggaaa ctggtcgggt atcgggtaat ggagtgtgat tcttcgttta
      781 agcaaggaga ttatcgtttg gtggttcata tttgcttgtt aaatgttagg gatgagatgc
      841 tgagtcagca aggccatgaa gataaagctg actggccaga gctttgagat gtgacgtttg
      901 gtggaagtcc tttttggtga gatggtacag catatagtaa tattagatcc tgaggaagaa
      961 ttgggacttt cattaggctt gactggggta tgacctcact ttacaattca tttcgatgat
     1021 gggtttgatg atacgttttt agtttaagac tttgtagagt tggagaattt ggttctttat
     1081 gaggaagaag tgcaggtaat tcgttgagcc agtcgtgaag atattttagg tatgattgat
     1141 gaaggttcgt tcattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggc
     1201 caatataaag tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt
     1261 atatttgata gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga
     1321 gcttctgcaa aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac
     1381 gatttatcga tggtcatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata
     1441 gatgacaata agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat
     1501 gatgtttata agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc
     1561 gtttacttgg aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct
     1621 gttactatca gagcattaaa tcagttatgg ctccttactc ttagccgaaa agatatgatg
     1681 gatattggta taccgattgg tagtgatgtg ccttattgct tgctttcagg ttgtgcccaa
     1741 gtcactggta aaggtgaagt ggtttgtcgc attttggggc tgttatcgtc ttgggtggtt
     1801 ttggttaaac cagattttgg tatctcgact tgaacatttt ttctagatat taattgtaaa
     1861 atcatttcaa gagtgtctac tactcatttg gttgcggcga ttgaagcggg taactataat
     1921 gatgggatat tgactgaaat gaacaatttg ctggaagata ttttcattgc caagcgaccc
     1981 tttattcaaa aaataaaaga gaaaacactg caagccggtg ctgctactgc tttgatgata
     2041 ggaagtggaa agactgtttt tgctttgtgc caaaccgaaa aacaaactat aatagtttaa
     2101 aaggactttg caaggaagtt tttaaggtga gaatgttgta atattttgtt gggattgctt
     2161 ctttggaagc ttcatgttat aattaactgg ttaatgaaag aggagattta tggggacttt
     2221 agaaaaaaaa cttgataact tagtaaatac tattttatta aaagcagaaa atcagcatga
     2281 gttattattt ggagcttgtc aaagtgacgt taagcttact aatacgcaag aacatatttt
     2341 aatgttacta tctcagcaac gtctcactaa tacagatttg gctaaggcat taaatattag
     2401 tcaggcggca gtaactaagg ctatcaagag tttggtcaaa caagacatgc tagcaggaac
     2461 taaggatacg gttgatgcta gggtgactta ttttgaatta accgagttag ctaagcctat
     2521 tgcatcagaa catacccatc atcatgatga aaccttaaat gtttacaacc gtttattaca
     2581 aaaattctcc gcgaaagaat tagagattgt agataagttt gtaacagttt ttgctgagga
     2641 attagaaggg taatccatga gatacatatc agtgaaaaat ctctcctttc aatatgaaag
     2701 tgagccagtt ttagaaggga tcacttatca tttagatagt ggagaatttg tcaccatgac
     2761 cggtgaaaat ggcgctgcaa agtcaacctt aataaaagca actttaggaa ttttacaacc
     2821 aaaggctgga cgagttacta ttgctaaaaa aaataaagac ggtaaacaat taaggattgc
     2881 ttacttgccg cagcaagtag ctagctttaa cgctggtttt ccatccaccg tttacgagtt
     2941 tgtcaaatca ggtcgctacc cacgtagtgg ttggtttaga cgtttgaaca aacacgatga
     3001 agagcatgtg caagcaagct tagaagcagt cggcatgtgg gaaaaccgtc ataagagaat
     3061 tggtagttta tcaggtggtc aaaaacaacg tgtggttatt gcccgtatgt ttgcttctga
     3121 ccctgatatt tttgtgctag acgagccaac aacgggaatg gatagcggta ctactgatac
     3181 cttttatgaa ctgatgcacc acagtgcaca tcaacatggg aaatccgttc tgatgattac
     3241 ccatgaccca gaagaagtga aggcttatgc tgatcggaac attcatttag tcagaaacca
     3301 aaaacttcct tggcgttgtt tcaacattca tgaagttgaa acagatgacg aaaaaggagg
     3361 tcatggtcat gcttgatatt ttatcctatg atttcatgca acgggcggta atggcggtag
     3421 ttgccattag tatttttgct ccgattttag gtattttcct tattttacgt cgtcaaagtt
     3481 tgatgagcga tacccttagt catgtttctt tggctggggt agcgcttggg gtagtcattg
     3541 gtatttcacc aaccatcact actattattg ttgtggtttt agctgctatt ttgttagaat
     3601 acctgcgtgt agtttacaaa cactacatgg agatttcaac ggcgattttg atgtcacttg
     3661 gtttggccct atctctgatt attatgagta agtcgcatag ttcatcaagc atgagtttag
     3721 aacaatacct ttttggatcg atcatcacga ttagtatgga acaagttgtc gccttgtttg
     3781 ctattgctgc gattatttta atcttgaccg ttctcttcat tagaccgatg tacattttga
     3841 cctttgatga agatactgct tttgtagatg gtttgcccgt tcgcttgatg tctgttctat
     3901 tcaatatcgt cactggggtt gctattgctt tgaccattcc agcagcagga gcacttttgg
     3961 tttctaccat tatggtcttg ccagcaagta tcgcaatgag attgggtaaa aactttaaaa
     4021 cagttatctt actgggaatt gtcatcggtt ttagcggtat gttatctggt attttcttat
     4081 cttatttctt tgaaacacca gctagtgcca ctattaccat gattttcatt agtattttcc
     4141 tcttagttag tctaggtgga atgcttaaaa aacggttatt ttaataagaa aaatcctcac
     4201 atgtttaaca tgtgaggatt tatttataaa tgctttaaaa agggggcaag gtcccaattt
     4261 tcttgattaa tggtgatgcc ctcccaaaag ctatcattag ttaaacgagg aatcaaatga
     4321 aggtgaaaat gagtcccctc atccatcaac tccttgtcat tgctgacgct agtgacgcct
     4381 gaaatgggaa ggtgctgctc tagcttagca actagagcgg cttgtaagtc gatgagatca
     4441 tagcgcactt cctttggtag ttgtgttaga ctagtgtaat ggtctttgga aatcagtaaa
     4501 aggtgcccct tttggatagg atcaatatca aaaacaacct tgaaatattg actttgagtc
     4561 agtagctgat ttgctttgag ctgatggcaa aagatacatt ctgtcatagg tacatctcct
     4621 tatgaaaaaa cgagccagag ctcgtttaat cggttatcta gtaagtgaga acagcgtatt
     4681 ttttcttacc gcggcgaata acggttaatt gatcatcaat tttatcatca ttacttaatt
     4741 ggtaatctaa atcttgaacg cggtctccgt taatgtagat tgctccattt tgcacgtctt
     4801 cacgcgcttg gcgttttgat ggggaaatac ctgcggtgac aagcatgtca acaaggttaa
     4861 ggctgtcttc tgattgaacg tgataatttg gtacattgct caatccttgt tttaattcat
     4921 tagcagaaag atttttgatg tttccagcaa ataactgctc ggtaatgtta agagcttgtt
     4981 tataaacttc ttcgctatga accaaggtaa ccacttcgcg tgccaaggtt ttttgagcga
     5041 gacgctcgtg acgagcggca ttaaattgag tttcaatttc tgcaatctca tctagagata
     5101 agaaggtgaa gattttcaag aaacgcactg catcatcatc catgacattt aaccagaatt
     5161 ggtacatctc gtaaggagac gtcttatcgg catcaagcca gacagcatta ccttctgatt
     5221 taccgaattt tttcccggtt gagtcagtga tgagtggtac agtcatgacg tgcccagttt
     5281 tatcagcctt tttgcggagc aattcagtac cagctgtcat attaccccac tggtcagagc
     5341 cgccaatttg taaggttaca ttatgcttgt cattgagttc gtagaagtcg tagccctgca
     5401 tgatttggta agcaaactca gtgtaagaaa tgcctgtttc aatgcgtttt ttaacagagt
     5461 ctttactcat catgtagtta acggtgaagt atttaccgac atcacggagg aagtcaataa
     5521 agctgatttg cgagaaccag tcgtagttgt tgacaagctc tgctttatta tcaccatttt
     5581 caaaatcaag gaaagtagac aactgccctt taatcttgtc gctccactcc aaaactgttt
     5641 ctttggtttg aaggctgcgc tctgcatctt taaaggaagg atcaccaatt aaacctgtgg
     5701 caccacccac aagagcgtaa ggtttgtgcc ctgctagttg caagcgacga gatgttaaga
     5761 tagccactag atggcccaga tgaaggctgt cagcggttgg atcataaccg gtataatagg
     5821 atacttgccc ttctgttaat gctttgacaa gggcttgttc atcagtcgtt tgaaagacca
     5881 agccacgagc tttgagttct tcaaaaatat tcataggctt tctccatttt cattatagtt
     5941 tcgaatcatt atatcaaaaa acgctactgc tatgcaagct ttatcaaagt ttggtataat
     6001 gataaatgag gtattttatg gtgaaatgga acacgaaaca aaagcgtata agtcatcaaa
     6061 gattaggtct cttggatttg gggccggtgc tattacgtac gttgagacta ctgtctaact
     6121 ttttttatat tgttatcttc ctttttggaa tgatgggatt tggtatggca tttgggtatt
     6181 tggctagtca gattgaatct gttaaggtac caagtaaaga aagtttagtc aaacaagttg
     6241 aatcattaac gatgatttcg caaatgaact attctgataa tagtttaatt tctactttag
     6301 atacggattt acttcgaaca ccagtagcta atgatgcgat ttcagagaat atcaaaaaag
     6361 ctattgtatc aacagaagac gaacattttc aaaaacataa aggtgtcgtg ccaaaagctg
     6421 tttttcgggc aacattggct tctgtattgg gatttggaga agctagtgga ggttcgacct
     6481 taacacagca attggtcaaa caacaagttt tgggagacga tcccacattt aagcgcaagt
     6541 ctaaggagat cgtttacgct cttgccttag agcgttatat gtccaaagac aatatcttat
     6601 gtgattatct taatgtttca ccttttggtc gtaataacaa gggccaaaat attgctggtg
     6661 ttgaagaagc tgcgcgtggc atttttggcg tttctgccaa agatttaacg gtgccacagg
     6721 cagcattttt ggcggggctt ccgcagagcc ctattgttta ctctccttat ttgtcaacgg
     6781 gacaactgaa gtcagaaaag gacatggctt atggcatcaa gcgtcagcaa aatgttctct
     6841 ataacatgta ccgtacaggt gttctgtcta aaaaagaata cgaggactat aaggcttatc
     6901 cgattcaaaa ggattttatt caaccgggaa gcgcaatagt aaataatcac gattaccttt
     6961 attacacggt gttagcggat gctaaaaaag ccatgtatag ctatttgatt aagcgagata
     7021 aggtgtctag tcgtgacttg aaaaatgacg agactaaggc tgcttatgaa gagagagcct
     7081 taacagaatt acaacagggt ggctatacca tcaccacaac cattaataag cctatttaca
     7141 atgcgatgca gacagcggca gctcagtttg gtggcctgtt agatgatggc actggcacag
     7201 ttcaaatggg aaatgtcttg acagacaatg cgactggtgc tgtgttaggt tttgttggtg
     7261 gtagagatta tgctctgaat caaaataatc atgctttcaa tacagttaga tcgccaggtt
     7321 ctagcattaa accgataatc gcttatggtc ctgctattga tcaaggttta atggggagtg
     7381 ctagcgtttt gtctaattac ccaacaactt actcgagtgg ccaaaaaatc atgcatgctg
     7441 atagtgaagg aacagccatg atgccacttc aagaggccct aaatacttct tggaacatcc
     7501 cagctttttg gacacagaaa ttactgcgtg aaaaaggggt cgatgtcgaa aattatatga
     7561 caaaaatggg ttataagatt gcagactatt cgattgaaag tttacctcta gggggcggta
     7621 ttgaaatctc ggttgctcaa caaaccaatg cttaccaaat gctttcaaac aatggcttat
     7681 atcaaaagca atatattgta gataagatta ctgctagcga tggtacagtc gtttacaaac
     7741 atgaaaataa gccaattcgt attttttctg cagcaacagc tacgatttta caagaattgt
     7801 tgagaggtcc gattacttca ggcgctacga ctactttcaa gaaccgtttg gcggctatta
     7861 atccgtggct tgctaatgct gattggattg gtaagaccgg aacaactgag aattatacgg
     7921 atgtttggct agtcctgtct actccaaaag ttaccttagg cggttgggca ggacatgatg
     7981 acaatacctc attagcgcca ttaacaggat ataacaataa ttctaattat cttgcctatt
     8041 tagctaatgc cattaatcag gccgatccca atgttattgg agtagggcaa cgcttcaact
     8101 tagatccagg agtcattaag gcgaatgtct tgaagtcaac aggtttacaa ccaggaactg
     8161 ttaatgtcaa tggacatact ttttctgttg gcggagaaat gaccaccagt ctatggtccc
     8221 aaaaaggacc gggggctatg acttaccgat ttgctattgg tggcacggat gccgattatc
     8281 aaaaagcctg ggggaacttc gggttcagaa aaaattaggt tgccatttat cgataaaaag
     8341 ggtataatag taataactat ttgtcgtcca atctagctga aatattgtcc agttaggaag
     8401 aacagcagtt aaatcacact gataaagtca gatttagctg ctctttttgt gtctattttt
     8461 agaaaagata gggtttgtaa cctatattta aatattctaa aaattaacat ttagggcaaa
     8521 tgataactta gttgcgattt gctgaaacag caaagcttaa atagaagaag gagctaaaaa
     8581 cttggcagga catgaagttc gatacggaaa acaccgtaca cgtcgtagct tttcaagaat
     8641 caaagaagtt cttgatttac caaatttgat tgaaattcaa actgactcat tccaagattt
     8701 cctcgattca ggtttgaaag aagtatttga agatgtactt cctatttcaa actttacgga
     8761 tactatggaa cttgaatttg ttggttacga atttaaagaa cctaaatata cccttgaaga
     8821 agctcgtatc cacgatgcaa gttattctgc accaatcttt gtgaccttcc gcttggtcaa
     8881 taaagaaact ggtgaaatca agacacaaga agttttcttc ggtgacttcc ctatcatgac
     8941 ggaaatgggt acttttatca tcaatggtgg tgaacgtatc atcgtttctc agttggtgcg
     9001 ttctccaggt gtttatttca acgataaagt tgataaaaac ggtaaagttg gttatggatc
     9061 aacagtgatt cctaaccgtg gggcttggtt ggaattagag actgactcaa aagacattgc
     9121 ctacactcgt attgaccgta cccgtaagat tccattcaca accttggttc gtgcccttgg
     9181 tttctcaggt gatgatgaaa ttgttgatat ctttggtgaa agcgaccttg ttcgtaatac
     9241 cattgaaaaa gacattcaca aaaatccaag tgattctcgt acagacgaag cccttaaaga
     9301 aatttacgag cgtcttcgtc caggtgagcc aaaaactgca gatagctctc gtagtctttt
     9361 gattgcgcgt ttctttgatg cacgtcgtta cgatttggct gcggttggtc gttacaaagt
     9421 gaacaaaaaa cttaatatca agactcgtct tttgaaccaa atcattgctg aaaaccttgt
     9481 ggatgctgaa actggcgaaa ttttggtaga agctggaact gagatgactc gtagcgtcat
     9541 cgaatccatc gaagaacacc ttgacggtga tttgaacaag tttgtttaca caccaaatga
     9601 ttacgctgtg gttactgaac ctgttgttct tcaaaagttc aaggttgtgt caccaattga
     9661 tcctgatcgt gtagtaacta ttgttggtaa tgccaatcca gatgataagg ttcgtgcatt
     9721 gacacctgct gatattttgg cagaaatgtc atacttcttg aaccttgctg aaggtcttgg
     9781 aaaagttgac gatattgacc acttaggtaa ccgtcgtatc cgtgccgttg gtgaattgct
     9841 tgccaaccaa ttccgcatcg gtcttgctcg tatggagcgt aacgttcgtg agcgtatgtc
     9901 tgttcaagac aacgatgtgt taacaccaca acaaatcatc aatatccgtc ctgtcacagc
     9961 agctgtcaaa gaattcttcg gttcgtctca gttgtcacag ttcatggacc aacacaaccc
    10021 attgtcagag ttgtctcaca aacgtcgttt atctgcctta ggacctggtg gtttgacacg
    10081 tgaccgtgct ggttatgagg ttcgtgacgt gcattacacg cactatggcc gtatgtgtcc
    10141 gattgaaaca cctgaaggac caaatattgg tttgattaac aacttgtctt catttggaca
    10201 tcttaataaa tatggtttca ttcaaacacc ttaccgtaag gttgaccgtg cgactggtag
    10261 ggtaactaac gagattgttt ggttgactgc cgacgaagaa gacgaataca cagttgcaca
    10321 ggccaattcg aaactaaacg aagatggcac ttttgctgaa gaaatcgtta tgggtcgtca
    10381 ccaaggtaat aaccaagaat tttctgcaag tgttgttgat ttcgttgacg tttcccctaa
    10441 acaggtagtt gctgttgcga cggcatgtat tcctttcttg gaaaatgatg actccaaccg
    10501 tgctctcatg ggtgccaaca tgcaacgtca ggctgtgcca ttgattgatc caaaagcacc
    10561 atatgttggt actggtatgg aatatcaagc tgcccatgac tcaggcgctg cggtgattgc
    10621 tcagcacaat ggtaaagttg tcttttctga tgctgaaaaa gtggaaatcc gtcgtcaaga
    10681 tggctcactt gatgtttacc acattaccaa attccgtcgt tcaaactcag gaacagccta
    10741 taaccaacgc acccttgtta aagtaggaga catcgttgaa aaaggtgatt tcatcgctga
    10801 tgggccttct atggaaaatg gtgaaatggc ccttggacaa aacccagtcg ttgcttacat
    10861 gacttgggaa ggttacaact tcgaggatgc tgttatcatg agtgagcgcc ttgtgaaaga
    10921 agatgtctac acatctgttc acttggaaga attcgaatct gaaacgcgtg atacaaaact
    10981 tggccctgaa gaaatcactc gggaaatccc aaatgttggt gaagaagccc tcaaagacct
    11041 tgacgaaatg ggaattatcc gtatcggtgc tgaggttaaa gaaggcgaca tcttagtagg
    11101 taaagtcaca cctaaaggtg aaaaagacct ttctgctgaa gaacgtttac ttcacgccat
    11161 ctttggggat aaatcgcgtg aagtgcgtga tacctcactt cgtgtccctc atggtggtga
    11221 tggtattgtt cgtgatgtga aaatctttac acgcgctaac ggcgatgaat tgcaatcagg
    11281 tgttaatatg cttgtgcgtg tttacatcgc tcaaaaacgt aaaatcaagg tcggagataa
    11341 aatggccggt cgtcacggaa acaagggtgt cgtttcacgt attgtaccag ttgaagacat
    11401 gccatacctt ccagacggaa caccagttga catcatgttg aaccctctcg gggtgccatc
    11461 acggatgaat attggtcagg ttatggaact tcaccttggt atggctgctc gtaatcttgg
    11521 cattcacatt gcaacacctg tctttgacgg ggcttcatca gaagaccttt gggacactgt
    11581 tcgtgaagct ggcatggata gcgatgctaa gacggtcctt tatgatggtc gcaccggtga
    11641 accatttgac aaccgtgtat ccgttggtgt catgtatatg atcaaacttc accacatggt
    11701 tgatgataaa cttcatgccc gttctgtagg accatactca cttgttaccc aacagccact
    11761 tggtggtaaa gctcaatttg gtggacaacg ttttggtgag atggaggttt gggcccttga
    11821 agcttatggt gcatcaaatg ttcttcaaga aatcttgacc tacaagtcag atgacgtcac
    11881 aggacgtttg aaagcctatg aagcgattac taaaggtaaa ccaattccaa aaccaggtgt
    11941 accagaatcc ttccgtgttc ttgtaaaaga attgcaatcg cttggtcttg atatgcgtgt
    12001 gcttgacgag gatgataatg aagtggaact tcgtgatctt gatgaaggtg aagacgatga
    12061 tattatgcat gttgacgatc tcgagaaggc acgtgaaaaa caagctcaag aaacccaaga
    12121 agtttctgaa acaactgacg aaaaataagc aatcaattct tattaaataa ttatttactg
    12181 gtctggggca aaggccccag gaactggtaa agtcatcaaa ggcagaaagg taaaactagt
    12241 ggttgacgta aatcgtttta aaagtatgca aatcacatta gcctcaccaa gtaaggtccg
    12301 ttcatggtct tatggtgaag ttaaaaaacc tgaaacaatc aactaccgta cattaaaacc
    12361 agaacgtgaa ggactctttg acgaagtcat ctttggtcca acaaaagact gggaatgtgc
    12421 gtgtggtaag tacaaacgta tccgttataa agggatcgtt tgtgaccgct gtggggttga
    12481 ggtaactcgt gctaaagtac gtcgtgaacg tatgggtcac attgagttaa aagctcctgt
    12541 atcacatatc tggtatttca aagggattcc atctcgtatg ggattgactc ttgatatgag
    12601 tcctcgtgcc cttgaagaag tgatctattt tgcggcttat gtggtcattg atccaaaaga
    12661 tacaccgctt gaaccaaaat cattattaac agaacgtgaa taccgtgaaa aactacaaga
    12721 gtatggtcat gggtcatttg tcgctaagat gggtgctgaa gccattcaag atctcttgaa
    12781 acgtgtggac ttggcagctg aaatcgctga attaaaagaa gagttgaaat ctgcttctgg
    12841 tcaaaaacgg attaaagcag ttcgtcgttt agacgtcctt gatgccttta acaaatctgg
    12901 aaataaacca gaatggatgg ttcttaacat cctgccggtt attccaccag atcttcgtcc
    12961 gatggttcaa ttggatggtg gtcgttttgc ggcatcagac ttgaatgact tgtaccgtcg
    13021 tgtgattaac cgtaataacc gtttggcacg tttgttagaa cttaatgccc ctggcatcat
    13081 tgttcaaaat gaaaaacgaa tgcttcaaga agccgttgat gctttgattg ataatggtcg
    13141 tcgtggtcgt ccaatcactg gaccaggaag tcgtccattg aaatcattga gccacatgct
    13201 taaaggtaaa caagggcgtt tccgtcaaaa cttgcttggt aaacgtgtag acttctctgg
    13261 acgttccgtt atcgctgttg gtccaaccct taaaatgtat caatgtggtg tcccacgtga
    13321 aatggctatc gagcttttta aaccatttgt aatgcgcgaa attgttgcca aagaatatgc
    13381 tggtaacgtt aaagccgcta aacgtatggt tgaacgtggc gacgaacgca tctgggatat
    13441 cttagaagaa gttatcaaag aacacccagt cttacttaac cgcgcaccga ctcttcacag
    13501 acttggtatt caggcttttg aacccgttct tattgacggt aaggcacttc gtcttcaccc
    13561 acttgtgtgt gaggcctaca atgccgactt cgatggagac caaatggcca ttcacgtgcc
    13621 actttcagaa gaagcacaag ctgaagctcg tcttttgatg cttgctgcag agcacatctt
    13681 gaaccctaaa gatggtaaac cagttgttac tccatctcag gatatggttc ttggtaacta
    13741 ctatcttacg atggaagatg ctggtcgcga aggcgaaggt atgattttca aggataaaga
    13801 cgaagctgtg atggcatatc gtaatggtta tgctcatctt catagtcgtg tgggtatcgc
    13861 tgttgacagc atgccaaaca aaccttggaa agacaatcaa agacataaaa tcatggtgac
    13921 aactgttggt aagattttgt ttaacgatat catgccagag gaccttcctt acctccaaga
    13981 gccaaacaat gccaacttga cagaaggaac agctgataaa tacttccttg aacctggtca
    14041 agatatccaa gaagtgattg acggcttaga aatcaatgtg ccattcaaga agaaaaacct
    14101 cggtaacatc attgcggaaa ccttcaaacg tttccgtaca acagaaacat cagccttcct
    14161 tgaccgtttg aaagaccttg gttactacca ttcaaccctt gctggtttga cagtgggtat
    14221 cgctgacatt cctgttattg ataataaagc tgaaatcatt gatgctgctc accatcgtgt
    14281 tgaagaaatt aacaaagcct tccgtcgtgg tttgatgaca gatgatgacc gttatgttgc
    14341 cgttacaaca acatggcgtg aagctaaaga agcccttgaa aaacgtctga ttgaaacaca
    14401 agatcctaag aacccaatcg ttatgatgat ggactcagga gctcgtggta acatctcaaa
    14461 cttctcacag cttgctggta tgcgtggttt gatggctgct cctaacggac gcatcatgga
    14521 acttcctatc ttgtcaaact tccgtgaagg tttgagcgtt ttggaaatgt tcttctcaac
    14581 ccacggtgca cgtaaaggga tgaccgatac ggcccttaaa acagccgact caggttacct
    14641 tactcgtcgt ttggttgacg ttgcccaaga tgttatcatt cgtgaggacg attgtggcac
    14701 tgatcgtggt cttcttatcc gtgctattac agatggtaaa gaagttaccg aaacgcttga
    14761 agagcgtctt caaggtcgtt acacacgtaa atcagtcaaa caccctgaaa ctggtgaagt
    14821 cttgattggt gctgaccaat taatcactga agacatggct cgtaagattg ttgatgcagg
    14881 tgttgaagaa gtgaccattc gttctgtctt tacctgtgcg actcgtcatg gtgtctgccg
    14941 tcactgttat ggtatcaact tggcaactgg tgatgctgtt gaagtgggtg aagcagttgg
    15001 tactattgct gcccaatcta tcggtgagcc tggtactcag cttaccatgc gtaccttcca
    15061 cacgggtggt gtagcctcaa ataccgatat cacccagggt cttcctcgta ttcaagagat
    15121 ctttgaagca cgtaatccta aaggggaagc ggtcattact gaagtgaaag ggaatgtcgt
    15181 cgagattgaa gaagatgcgt caactcgtac caagaaagtc tacgttcaag gtaaaactgg
    15241 catgggcgaa tatgtcgtac catttacagc acgtatgaaa gttgaagttg gcgacgaagt
    15301 taatcgcgga gctgccctta cagaagggtc aatccaaccg aaacgtctcc ttgaagtgcg
    15361 tgataccttg tcagttgaaa cgtaccttct tgcagaagta caaaaagttt accgtagcca
    15421 aggggtagaa atcggagaca aacacgttga ggtaatggtt cgccaaatgc ttcgtaaagt
    15481 tcgtgtcatg gatccaggtg atacagacct ccttccaggt acacttatgg atatttctga
    15541 tttcacagat gctaacaaag atattgttat ctctggtggt attcctgcga catctcgtcc
    15601 tgttcttatg ggtattacta aggcttccct tgaaaccaat tccttcttat cagctgcatc
    15661 cttccaagaa acaactcgtg ttcttacaga tgctgctatc cgtggtaaga aagaccactt
    15721 acttggtctt aaagaaaatg ttatcattgg taaaatcatt ccagctggta ctggtatggc
    15781 gcgctaccgt aacattgaac cacaagcgat gaatgagatt gaagtgattg atcatacaga
    15841 agtctcagca gaagccgttt ttacagcaga agcagaataa tctcatgaaa gagtccttag
    15901 gggctctttt ttgtctgagt ttgttggcag taaaaagcat tgacaatcag tcttagtccc
    15961 aatgagcaga tgtttttcaa aatacttatg atttagctat aataatgcat aagaggaata
    16021 ggtaatgtgt tatgtatcaa gtaattaaaa tgtatggtga ttgggagcct tggtggttca
    16081 tcgatggatg gcaagacgat attatagatg agcaacaatt tagtgactgg caagaagcgc
    16141 ttgattattt taatcaagaa tggcagcgca tgaaagctat ttttcctagt tatcatagtc
    16201 aaaagaattt gttagctact ttttgggaaa aagaagataa aagatggtgc gaggactgtg
    16261 acgaagattt acagcagttt cattctcttt tactccttaa aaataaagat attgtaccaa
    16321 gcaataatta tatccctgaa tttgaacaac gaaatgattc accacaggta gcttatcttt
    16381 gcaagttaaa cctttaagtg tttgttaaaa acaaaataag ttaaaagaaa atatcacttc
    16441 ttctgatatt ttcttttttt gtttacgaat aaatgagtaa ggaggaatta tggtacaagc
    16501 attagcaaaa gctattctag caaaagctga acaggttcag gcacaagata tttatatttt
    16561 gccaagagca gatcaatatg atcttttttt acgaatagga gatgaaagga gattagttga
    16621 tgtttatcag agcgatcgga tggctcctct tattagtcac tttaaattcg ttgcaggaat
    16681 gatagttggt gaaaagagac gttgtcaggt gggttcatgt gattataagc ttagtaaaga
    16741 taagcagtta tctttgcgct tatctagcgt gggtgattat cgcgggcatg aaagcttagt
    16801 gattcgtctg cttcatcatc aaaataaaag tgtacattat tggtttgatg gattgacaaa
    16861 agtagccaat caagttggcg gtagagggtt gtatttattt gcaggaccag ttgggtctgg
    16921 gaagacaacc ttgatgtacc agctgatttc gagttatcat caagaagcac aggttattag
    16981 tatagaagat cctgtagaaa ttaaaaatca ccagatttta caattacaag tgaatgatga
    17041 tattggtatg acttatgaca atttgatcaa actgtcttta cgccatcgac cagatatttt
    17101 agttattggt gagattcgag atagtcaaac agcaagagcc gttattaggg ctagtctaac
    17161 aggtgccatg gttttttcaa cggttcacgc taaaagtatc tcgggtgttt atgcaagatt
    17221 gttagaactt ggtgtaacga aagcagaact gtctaattgc ttagcattaa ttgcttacca
    17281 aaggttactt aatggaggag cattgattga ctctactcaa aacgaatttg aatattattc
    17341 ctcatcgaac tggaatcaac aaattgatca gcttcttgag gcaggacatc tcaatcccaa
    17401 gcaagctaag cttgaaaaaa ttatctagta aacatcagca taaattcatt caattactag
    17461 ctaatctttt atctacagga tttagcttca cagaggttat tgctttttta aaaagaagcc
    17521 agttgcttca gctagattat gttcttaaaa tggaagagtc tttattaaaa ggacaaggct
    17581 tagcagatat gttgtcgggt ttaggttttt cagatgctat tcttactcaa attagtttag
    17641 ctgatagaca cggtaatatt gaaacaacat tagtagcgat tcaacattac ttgaaccaaa
    17701 tggcaaggat cagacgaaaa actgttgaag ttatcaccta tcctcttatt cttttacttt
    17761 ttctttttgt aatgatgcta gggttgagac gctatttagt ccctcaatta gaaactcaaa
    17821 atcagataac ttactttctt aaccattttc ctgccttctt tataggtttt tgctcaggtc
    17881 ttattttgtt gttcgggatg gtatggctac gatggcgatc tcaaagccgc ttgaaactct
    17941 atagtcggct aagccgttat ccttttttag gtaaactgtt aaaacaatac ttaactagtt
    18001 attatgctag agaatggggt acgttaatag gtcaaggtct tgatttgatg gctattttag
    18061 acattatggc cattgagaaa tcctcactaa tgaaagaatt agctgaggac atcagaatga
    18121 gtctgcttga agggcaagcc tttcacatta aagtagctac ctaccctttt tttaaaaaag
    18181 aattaagttt aatgattgaa tacggtgaaa tcaaatcgaa actgggggct gagttggaaa
    18241 tctatgccca ggaaagctgg gaacaatttt ttagtcagct ttatcaagtg acacaactta
    18301 ttcaaccagc tattttttta gtagttgctg tgacaatcgt catgatttat gcggcaatcc
    18361 tattaccaat ttaccaaaat atgggaggta ttttttaaga tgattaatca atggaacaac
    18421 ttacgacaca agaagctaaa aggatttact cttctagaaa tgttattggt gattcttgtc
    18481 atcagtgttt tgatgctatt atttgtgcct aatttaagca agcaaaaaga cagggttaca
    18541 gaaacaggta atgccgctgt tgttaaatta gtggagaatc aagcagaact atatgaatta
    18601 tctcaaggct caaaaccaag tttgagccag ttaaaggcag atggtagtat cactgagaaa
    18661 caagaaaaag cttatcaaga ctattatgac aaacataaaa atgaaaaagc ccgtcttagc
    18721 aattaaagct tttactttgc ttgaaacttt actaagtttg tcagtgatga gtttcattat
    18781 attgggattg tctgtaccag tgacaaaaag ctatcaaaaa gtagaagagc atctgttttt
    18841 tagccatttt gaacatttgt atcgacatca gcaaaagtta gccatattac agcaaaaaca
    18901 gcgcgtcttg gatatttctt caacaaaaat tgttacagaa ggtaatagcc taacagttcc
    18961 taaatcaata acagtgaatc atccttatcg gttagttatt gatcagatgg gaggcaacca
    19021 ttccttagct aaaattattt ttgacatgac tgatcgacgc tttaaatacc aattttatct
    19081 agggagtggg aattatcaaa aaacaagtca aagcttacat agcccttgaa agtatgattg
    19141 caacaggcat cctctttagt attgtcattc tcgtcttaag cagtttacag cagagtcagg
    19201 ctgctctaac gtactatcga aagcagcaag aaaagcttaa tctagccttg atggcagtac
    19261 aaactagaac taaagagata acattgaatg gttgtcatat tactatttta cgtacggata
    19321 gatacattag tattcacgat gacgaaggag aagtgatgaa gattgagtaa acaattaagt
    19381 aacataaaag cttttactct tctagaggcg ttaatagcct tactcgtgat atcagggtct
    19441 ttattggttt atcaaggttt gacccaaacc ctccttaaac gtagccatta tctagcccgt
    19501 catgatcaag acaattggct cttattttct catcaattgc gagaggagtt aagtggagca
    19561 agattttaca aagtagctga taataaacta tacgttgaaa aaggaaagaa agtactagct
    19621 tttggccaat ttaaaagtca tgatttccga aaatcagcta gtaatggaaa agggtatcaa
    19681 cccatgttat ttggaatatc acgtaatcat attcacatag agcagtcaca gatttgcatt
    19741 actttaaagt ggaaaagtgg gttagaaagg actttttatt atgcctttca agactaatct
    19801 caaagcaggc atccttttgt atgctatgtt tatggctagt atttttttgc tggttttaca
    19861 ggtttacctt tctcaagtga cagctctaca caaggaatac caagctcaaa ctgactatgt
    19921 taaagcccga ctgatagcag aaatagttta tcaagatcat agatataaag cttctaatcc
    19981 tgtttctttt aaaggtggtc aagtcatttg tcgagagcga aaagagagat ggatgttaat
    20041 tgttaagtta gatcagcaac gacagtatca gtttgaatac cttaaaccca aacaatatag
    20101 tcaataaata gtattgttgt cataaatcct taaaatgatc caatatatag taattaaagg
    20161 tgacacttct tttcatttca agtgtaattt ggtatgataa ggttatgact tttgaaaaaa
    20221 ttgaagaagc ttatcagctg ctcttagaga actgtcaact aattgaaaat gatctaaaaa
    20281 cacatatata cgatgccatt gttgaacaaa actcctttta tttaggggct gagggagcta
    20341 gtcctcaagt tgctcaaaat agtgataaac tgaaagcctt gtgcctgaca aaagaagaat
    20401 ggcgtaaggc ctaccagttt ctttttatta aggcagctca gactgagcaa ctccaagcca
    20461 accatcagtt cacaccagat gctattggct tcattctgct gtatcttttg gaacaattga
    20521 gtgataaaga tagcttagag gtacttgaga ttggaagtgg aacagggaac ctagcccaaa
    20581 cccttctcaa caacacgagc aagagccttg attatgtagg gattgaactt gatgatctct
    20641 tgattgatct gtcagccagt attgctgaga taatggattc ttcagctcat tttattcaag
    20701 aagatgcggt aaggcctcaa ttactaaaag aaagtgacat tgtcatcagt gacttaccag
    20761 ttggttatta tcctaacgat gatattgcca aacggtacaa ggtggctagt tcagataagc
    20821 atacctatgc ccatcattta ttaatggaac agtctttaaa atacttgaaa aaagacggtt
    20881 ttgcgatttt tctggcacca gtcaatttat tgacgagccc tcagagccag ttattgaaac
    20941 agtggttaaa agattatgct caggtggtga ccttgattac gctaccagat tctatttttg
    21001 gtcatccctc aaatgccaag tccattattg tcttacaaaa acaaacagac cacccaatgg
    21061 aaacctttgt ctatccaatt cgggatttga agcttgcaga gaatattcat gattttatgg
    21121 aaaatttcaa aaaatggaaa ctgagtaatg tcaattaatt gattttttgt tataataaaa
    21181 aagcatcaca gaaaacgatt tcaagagagg ttaaaaatgt caaagacaat tgcaattaat
    21241 gcaggtagtt ctagtttaaa atggcaactt tatcagatgc cagaagaagc agtgttagca
    21301 caaggaatta ttgagcgtat cggtctcaag gattctattt caacagttaa gtacgatggc
    21361 aaaaaagaag agcaaattct tgatatccac gatcatacag aagctgttaa aatcttattg
    21421 aacgatttga ttcactttgg aatcattgca gcttatgatg aaattacagg agttggacac
    21481 cgtgttgttg ctggtggtga acttttcaaa gaatccgttg tggttaatga caaagttctt
    21541 gaacatattg aagaattatc agttttagct ccacttcaca atcctggagc ggcggcaggg
    21601 attcgtgcct tccgtgatat tttgccagat attaccagtg tttgtgtgtt tgacacgtca
    21661 tttcacacta gcatggcaaa acatacttac ctttacccaa ttcctcaaaa atattatacg
    21721 gactacaagg ttcgtaaata tggggcgcat gggacaagtc ataaatatgt agcgcaagaa
    21781 gctgctaaaa tgcttggtcg tccattagaa gaattaaaac taattactgc tcatattgga
    21841 aatggtgtct caattacagc taattaccac ggtaaatcag ttgatacctc aatgggattc
    21901 actccattag ctggtcctat gatgggaaca cgttctggtg acattgaccc agctatcatt
    21961 ccttatttaa ttgagcaaga cccagagtta aaagacgctg ctgacgttgt taatatgtta
    22021 aacaaaaaat caggtcttag tggggtgtca ggcatttcta gtgatatgcg tgatatcgag
    22081 gctggtttac aagaagataa tccagatgct gttttagctt acaatatctt tattgatcgc
    22141 attaaaaaat gcattggtca atattttgct gttttgaatg gagcagatgc tttggtcttt
    22201 acagctggta tgggtgaaaa tgcaccattg atgcgtcaag atgttattgg tggcttaaca
    22261 tggttcggaa tggacattga tcctgagaaa aatgtttttg gataccgtgg tgacatttca
    22321 actcctgagt caaaagtgaa ggtgcttgtt atctcaacag acgaagaatt gtgcatcgcg
    22381 cgtgacgttg aacgtttaaa aaatacaaaa taaaagagac taagtctcaa tagattaacc
    22441 aagtaaggta acactttact tggtttttta tgaggtttat ctgttggtta tggtgcctag
    22501 gtattagttc tgatcagtct ccttgctttt tgtaatcttg tgctaggcga tttggatgtc
    22561 agccttattt agaagttttt aattgcttca acgcttttct tgtatgtgtt tatagagccc
    22621 aatgatctaa aagactattt gataacggtt tatgatgagc gtaatcgtgc gattcgaaaa
    22681 cagacacaag tttactgctt ttacctgatg attgttctat ttgttgcctt attctttttc
    22741 ttcccttgct taaccatttg agaccttgtt tcttataagc tacctttgat ttttgcttac
    22801 ctttacttga ttatcagaag tctggtggct aagaaaatgg aggcactagg gaaaataaca
    22861 actaatagtc aaaaacctcc gtttgatacg agtcaggttc tttgttagat gacttgtcta
    22921 acggttgagt ttcctgtctg gtcaacggag gtgtttgtat tgttgtctga tttgtattgg
    22981 ggcacttatt ttacaagctt ttagccttat cgatggtttt gtcaatggca gagctgacag
    23041 tagttgtgag gccaaggcgt tctaactcca ttagaccagc aatagttgtg ccaccggggc
    23101 tacaaatagc gtcaatgaaa tcgtgcggac tttgagaact ggtcttgaga ttgctggcac
    23161 tagccaagac tgtttgagta acaatctcta gcgcctttgc tttaggcatg ccattcttga
    23221 cgccagcctt agccaaagcc tcaataaaga gataaatata ggcaggactt gaccctgcta
    23281 aagcggtaaa ggtgtcaaaa tccttttcac taatatcaaa tgtgctacca aagctatctg
    23341 ttaagtctcg aacacgtgct tgtaattcct gggacaccaa agcatttccc gttaaagcgg
    23401 tactgctttg gagaatttgt gcattcatgt ttggcatgat acgtagcagc ggaaggtctt
    23461 gtcctacgaa tgttgctagt cgttgaaggg aaatgcctgc tgccatagat ataataggct
    23521 gtttgaagtg aagcggtttg agtaccgttt caaatagttg aggcttgatg cctaaaataa
    23581 caagatcaac ctggtcaata aggtcttggt gggacatagc ataaggcagt gttaactgct
    23641 ccgcaatttc cttggaccgt tctaaagatg atcctgaaat gataagttca tggggtgttt
    23701 gtttaaggcc tttgatgata gcgctagcca ttttgccaac accaataatg ccaattttca
    23761 ttctgttgct ccttgtggga tattacggtt aatcaggcta acgctagttt agtaacgttt
    23821 aatcaagtca acggttgagc gatccagttt tttgataatg gcttgtaaga aggcttgggc
    23881 ttctacgaaa tcatccatag cgtagagggt ttgatgagag tgaatgtagc gtgcacagac
    23941 tccgatggtt gttgatggga caccaccatt ttgaaggtgt gcagcacctg catctgtgcc
    24001 tcccttgcca caatagtatt ggaaattgac accagcgtcc tcagcagtag tcagtaagaa
    24061 gtcgcgcata tctttgagca tgacatggcc tgggtcgtaa aagcgcaata aggtaccatc
    24121 tccgattgtt ccaggattgc cataaatatc accagcaggc gaacaatcta ctgcgaaaaa
    24181 gagttcaggg tcgaacttgg tggttgagac gtgggctccg cgcagaccaa cttcttcttg
    24241 aacgttagca cctgcaatta gggtgttgtt aaggtcttgt ccttttaacg cttcaagcat
    24301 ttctgttatc atgagaacgc catagcgatt gtcccaagct tttgaaataa tatttttttg
    24361 attggctgtt aggatcgttt cagattgagg gacaataata tcacccggtg taatgccaaa
    24421 gctttcagct tctgccttat ccgtaaagcc accatcaaac acaatatctt cgatatttgg
    24481 tagactagca gagccatttg ccccacgtaa aaaatgggga ggtaccgatc ctgaaataag
    24541 gggaataact tggccagtgc gtgtgtaaag ggtaaaccgt tgtgaactga caacaagtgg
    24601 gttccaacca ccgataccaa ccacgcgtag cgttccgtca actttgatat cactgaccat
    24661 aaaaccgact tcgtccatgt gcgcagctac taaaatacgg ggggcttttt cagctttact
    24721 atctctgata ccaaaaatgc caccaagccc gtctgtttca acacggtcaa ccagcggggt
    24781 tattttggtg cgtaggtagt cacgaacgct atgttcatag cccgcaatgc catccagttc
    24841 ggtaacttct ttgatttttg agaataagtc tgtcattttt catctccatt taaaaggttt
    24901 cagaccagtt caacgcggtc atctccttat attctaccac tttttaagta agaatgggtt
    24961 tcacagaaaa gaaaaatccc agagactaga gatctctgga agaagtgttt gtcttttggc
    25021 gataacctgt ttttttaggc agcaaggaaa tcattaaaat gataaagcac aagctggtta
    25081 ataagaatag tagggcgctt aggatgcgaa aagactcttc actagcgaaa agtaaggata
    25141 atggagtcat aaggagaacc ttccatttta ggttaatcag tgatttttat agcgtggtta
    25201 aattaataat aaaccacacc taatcaacgt acctttagtt tagttgtttt tactattttt
    25261 gtcaatacat aacagtagaa atctttagtt ttcttatttc agatcgtcca atttgatctt
    25321 tttatgataa aatgagggat atgagtaaaa agaaaatagg tatgatttca ggtatctttg
    25381 gatttagttt agctattggc ctaggaatag ttatcaaaga ttattgccaa gacaggcagc
    25441 gtcgacaaat gacaagggat ttacgcacct ttttttcacc tttaggacaa atcgaagttt
    25501 tatatatcaa tccttgtcag gtcaaacaag attatatttc aggtggggtt gttatgtcaa
    25561 acggcaaaca gtaccaattc acctatcaca gtcgacaaat tagttttgag gaggacaagg
    25621 gatgatcaga ccgacttctt atgagtcgtt agcggctctt attgaaaaag aagataagct
    25681 ggtgttattt tttacggcag actggtgtcc agactgtcaa tttatttatc ctattatgcc
    25741 agaaattgaa gcagaactta cagatatgac ttttgtttgt gttaatcgtg atcagtttat
    25801 agaggtagca caaaagtgga atatttttgg tattcctagt tttgtcgtga ttgaaaaagg
    25861 tcaggaagta gggcgtctgg ttaacaaaat gagaaagaca aaaactgaga ttatgcattt
    25921 tttagctgct tatcaataag aaaagaggaa gaataaatga tttttgcata caataaagaa
    25981 caagttggcg atgtcttgat ggttatctta caagacacca aagatatcaa acgtcaagta
    26041 gaacgaaaag gcaaagtagc ccgtgttttt gcagaagaaa gcggcaaaac ccttgcttgg
    26101 aatatctttg aagcgtcaag cttgattact attgaaggca atggacagat ttttttgaca
    26161 gacgaggacc ttgcaagatt aaatgcagag cttgctaagg aaggattttc agaaaggctt
    26221 gaaccgattg tgggacctgt ttttgtggtt ggtcaaattg ttgaaatggt ggctcatcca
    26281 gatagcgacc atcttaatat ctgtcaagtg gctattggtg aagatcaaac ggttcaaatc
    26341 gtagcgggcg caccaaatgc tgcgcttggt ttaaaaacga ttgttgcctt accaggtgct
    26401 ataatgccaa atggtagtct gattttccca ggaaaattgc gtggtgaaga aagttatggt
    26461 atgatgtgct ctcctcgtga gttagccttg ccaaatgcac cgcaaaaacg tggtattatt
    26521 gaacttgatg agtcagctgt ggtaggagaa gcttttgacc cagccaaaca ttggaaaggt
    26581 tagaaaaacc agctgaaata agactgtatt taactaaatg accagaaaaa aaggattagg
    26641 agcccttaat ccttttttct tatgttttca aaaacgttta aaatgaaact tattttacca
    26701 caatttttac gaataataag ataaggaggt cagtatgtat aataaagtga tagcaatcgg
    26761 tcgtttggta gctaaaccag aattggtaaa aacagctacg gataagcatg tagcacgtct
    26821 ctctttagct gttaatcgaa gatttaaaaa tgcttctgga gagcgagaag ctgattttat
    26881 ttcagttgtt gtttggggaa agttagcaga aactctggtt tcttatgcta gcaaaggtag
    26941 tttgatgtct attgatggcg aacttaggac ccgcaagtat gataaagatg ggcaagtgca
    27001 ttatgtgaca gaagttctct gccaatcatt tcaactgctt gaaagtcgtg ctcagcgcgc
    27061 tatgagagaa aataatgtta ctaatgatct agttgattta gtcttagaag aagatactct
    27121 tcccttttga tagaggctaa tgcttctcat cagggttcag ctgattactg aaatatatga
    27181 tgaggtgata tccgagcaac aaaagtgtga ctagatactt ctgataaaaa taaaaaaaca
    27241 ccttacgagt atgaacaaag tttcaagtgc tagatgttgg aactttgttc atactcgtaa
    27301 ggtgtttttt agtgtattac ttctttttgt tgctagtgtt aaggtttact tgcttacaag
    27361 cggttatcag gccactagaa ctcttataat aaatggagct ctttgagttt ggtgtcaatc
    27421 atttttaaga cagtcgccaa atcttgtggg ttctgaacaa aatcaaggga attgccatca
    27481 attttcattt ttggagagac ctcgtagtct tcgtaccagg ttgggtattc accgtggact
    27541 tgatggtaat attgctcaag actaggattg ccgtcgacct gctcaaaact tcggccacgt
    27601 ttttcaatgc gctcaagcat tttgtcaaaa gacacatcaa tgtagatgag aagatcaggg
    27661 cgttttttag gcatgccttc tagttcttct aacatgttgg cgagaagttc ctgatagatg
    27721 tcaagttctg tcttagtgac attgccattt ttgtagttaa gttttaagaa gagttcgtct
    27781 tcaaaaatag agcggtcaag aatgttgtta tcggcttgat aagcttcttt gatggactta
    27841 aaccgtttat tcaaaaaata aatttgaagt aaaaaggcgt actttttagg gtcttggtag
    27901 tagaggtcta gcacggggtt attatcaaca gcttcgtaaa aaacgtcagt tcctaaatgc
    27961 tctccaagtg cagcagcaag cgagctcttg ccagccccaa ttgttccagc tagtacaatc
    28021 aacatgcgtc tccttctaat gtcattagcg tactgtttcg aagatggctt caacctcagc
    28081 tagagtctca gcgcgtgaaa cagcaccacg aactttggca gcacctgctg ttccacgaag
    28141 atagtgtggc gctaagcccc gaaattcccg aacagcaatg gtttcacctt tgaggttaat
    28201 taggcgtttg aggtggtctt tggcgatgtc taattttttg gcaaagggaa gatctggcaa
    28261 ttcttgacca gtttcaaaga aatgattgat ttgggtaaaa agataaggat tgttcatggc
    28321 tgcgcggcca atcatcacgg catctacacc gatttcttca atcataaatt tggcgtcttg
    28381 caccgaacgc acgtccccat ttccaataaa gggaatctta gtgatagcct tagaaactcg
    28441 ggctaatgtc tcatggtcgc aggttcctgt atacatttgc tcacgggtac gaccgtgcat
    28501 ggcaagagca gatacacctg ccgactcagc ggcaagggca ttttcaacag caagtgaact
    28561 atccgcccaa cctgtacgca ttttgacagt cagtggaata tctaaaacag acgtgacttc
    28621 cttgacaatg tggtaaatct tatcagggtc acggagccac ttggcaccag cctcgttttt
    28681 gacaacttta ttaacagggc agcccatatt aatatcaaca atatcggcct tggtattggt
    28741 ttgaatgaaa tcagctgcac gtttcaaccc ttctgcatca ccaccaaata attgaatgga
    28801 catagggtgc tcattctcgt caatatggag catatggagg gtcttttcgt tgttgtagag
    28861 cagccctttt tcggaaatca tttccataac caccaaacca gcaccaaatt ctttggcgat
    28921 ggtacgaaag gcagaattgg tcacaccagc catgggagca aggacagtgc ggcgagggat
    28981 ttccacatca ccaatcctaa aggaagaatt aagctttatc attgatgatg gcctccaaat
    29041 cactttcatt aaattggtac ttggtaccac aaaattggca aacaatctca gcacccttat
    29101 cttcgtcaat catggcctgt aaatctgctt ttggcaaagt cattagggct gcttcaaaac
    29161 gttctctaga acagtcacac tgaaaactca gaggttcttc agaaagacgc ttgtaaggtt
    29221 catctccata gatggcctcc aaaagggcat ccacatgatt tttggaagct agtaggtaag
    29281 aaatggcagg catttcttgc aggcgttttt catagcgagc aatctcttct tcagaagctc
    29341 ctggaagcac ctgcaccata aagccaccag caaccttgac cttatcattt tcatctaaaa
    29401 gcacattaag tccgattgca gatggtgttt gttctgattc ggttaagtag taggcaaaat
    29461 cctcaccaat ttctccagta ataagaggcg ttgttgaggt gtaagggtta cctgtgccat
    29521 aatcaataat cgtcacaaaa tgaccattcc ccataaaagg cccaacaagg acttcacctg
    29581 ttgcggtctt tttaatatcg acaccagtat tttgaatgta acctttcaca tgtcctttgg
    29641 tatctgccac agagataatg tgtccaaaag aagaatcacc aatcactttg acggtgattt
    29701 tactatcgcc tttttgatta gccgccaaaa tctggttggc gatcaaggta cggccaagcg
    29761 caacagtaga cgatgacagc gtgttgtgtt tttcttgagc taatgcaacc gtctcagtgc
    29821 tatcaaggac gtaagcccta aaagcccctg attgtgctat tgatttaatt attttatcca
    29881 taacttagat tatagcataa agtgtaaaac ttgtattgac aggattactt gaaaaatcaa
    29941 tacagataga cagtaaaaaa tcccagagaa tgactcggga ttaagttaag gtgtggtcta
    30001 aagtcgcgca atgtggtgac atggcgctta tgttaattgc ttggttaaat cagcttggaa
    30061 tttttcctct ttaacttgat atatcaattc ttggatagat agaatcgatt catcaaaaga
    30121 tatttcagca acagcaattc cttttgtaag ctcatgttga acaaaaggaa tcagttggct
    30181 gtgagtgatg accaaatctg gctttaaatc aggaatttga taaacattat cttgcaataa
    30241 ataataggaa tgaaaattaa tgcttttatc cgagaaatac cttgggaaag aatctgttag
    30301 gagatgagca ttgataaaat tactggctac gaaaacaaca actaaaggag gttggatatt
    30361 tcttagaatt tgctcgacat agtggcaaaa aagatgaaaa tgcttatggt tcaagtaacg
    30421 cttaccagga agtttggcca tccactcttc gacaattaac tttaaggacg tatagagttt
    30481 ttggtttcct ttatagtacg gagaaatgaa taagttggtc tcaggaataa aatgttgcag
    30541 attaaacaag aatgattttg aaaaaaacat aagagctttt actaaactag ccttttgctc
    30601 ttttaggtta ggtaaaagag tgatgatagg atttaaaagc aggcgaaaag tatcattttc
    30661 ttcaaaaagt tgacaacatt gtctgatatg ctcaggtgtc cattgtaagc tcgcaaaaga
    30721 attattagcg gtgatataaa ttaaatagag gtagtccaaa tctcctgctg aaaagtttag
    30781 ttggcagtaa gtttcgataa tatcacggct actttttttc aaagaatcgt agacaaaaag
    30841 tttttttaat tgttgaaaaa ttctggtttg gggaatagtt accgaaaatt gatgccgctt
    30901 ccacgataaa gccaataaaa tgtcatagaa agaaaacgat tccgataacc aaggagaggt
    30961 tttaaggtgg gtggaactat gggataaaaa gctatgaata gtgtttttgt cttgctgcgt
    31021 caagtcataa actttaatgc caaacttact atatagcaga gcgatgaggt aacggatgcg
    31081 atattcctca ccgacaatct tgttcttaga gagttttaat tcaaagtttc ttaataaggg
    31141 aaccaatgct tcgcgcatcc gataagctga ggagtttgat aaaaaatgac ttctcgcaaa
    31201 atccgtaagg ggacgagagt gtgaaccatt ttttattaaa aaggctagta attgtaagac
    31261 attagatgat gcatagagtt ggtaaagata agtttcttta aaaggatgtg taaattggca
    31321 agatatcatc cttttttgga tggtcataga cagactacca gggaaaaagg cattcagttc
    31381 ctcacaataa tggtttagtt gtaaaaaggt taagccagtt ttttctgctg cctcagttat
    31441 tgacaaataa gatgtcttaa aaaacaagac aattaactga cattttgatt cgattgatga
    31501 ttccaagtat ttttctatca aggaaagggg tcctctcttc ctacacttag aaagccaaat
    31561 aagtctttga taagtgtatt ctcctatttc aattctatct aagctaaaaa tagaaatcaa
    31621 atctaattgt ttttggtgaa aagtcgaaac cttttgaaat agctttaaag caatattttc
    31681 tcaaaaaatc attttcaaaa acactaattt ggtgaaatat acaatcaaaa aaatatcttt
    31741 cttgacaata acatggtaag ctcatatatg tttgtgagag gagagaaaat gaataacaaa
    31801 atgtttttga acaaagaagc cggttttttg gcacacacaa aaagaaaaag gcgatttgct
    31861 gtcactttag tgggagtctt ttttatgctt ttggcatgcg cgggtgctat ccgttttggt
    31921 caagtagcct atgctgcgga tgagaggact gtgccgaatt ttaaaagccc agatccagat
    31981 tatccctggt atggctatga tgcttatact ggagcgtttt taagatatca tgatcttaga
    32041 gtcaatttaa acggaagtcg gagctaccaa gtttattgtt ttaatattaa aaaaaactat
    32101 cctcgacctt ttacgagtag tgataaaaaa tggtataaaa gattagaggg aactgctgaa
    32161 acttttaaag ttcatgctat ggctcccaga gtagggggag aggaactaac taaaaaatta
    32221 cggagcgtta tgtataacgg ctaccctaat gacggcaata atattatgaa aggtttggag
    32281 ccttcaaatg ctatagaagt aacacaatac gcagtttggt actattcaga taagtcacag
    32341 tatgaaattg agacattatg gaagtctgaa gcgaaagaag gtaagattag tgagtcacaa
    32401 gttactttaa tgcgtgaagc cctgaggaaa ctaatttcct ctgatgaaga tttggttaaa
    32461 caagttccat cgaactttaa acttagtact tttgagtctt ctgataagtc ctaccaaaat
    32521 cttttaagtg ctgagtttgt acctgatgat ccccctaaac ctggtgatac gtcagaacat
    32581 aatcctaaaa ctcccgagtt ggatggtagt cctattcccg aagacccaaa acatccagat
    32641 gataatttag aacctacatt gccgccagtg atgctagatg gtgaagaagt cccagaagtt
    32701 ccaagcgaga gcttagaacc tgcgcttccc ccattgatgc cagagctaga tggtgaagaa
    32761 gtccctgaaa aacctagtgt tgacttacct attgaagttc ctcgttatga gtttaacaat
    32821 aaagaccagt cacctctagc gggtgagtct ggtgagacgg agtatattac cgaagtctat
    32881 ggaaatcaac agaaccctgt tgatattgat aaaaaacttc cgaatgaaac aggtttttca
    32941 ggaaatatgg ttgagacaga aaatacgaaa gagccagaag tgttgatggg aggccaaagt
    33001 gagtctgttg aatttactaa agacactcaa acaggcatga gtggtcaaac aactcctcag
    33061 gttgagacag aagacacgaa agagccagga gtattgatgg gaggtcaaag tgagtctgtt
    33121 gaatttacta aagacactca aacaggcatg agtggtcaaa cagctcctca ggttgagaca
    33181 gaagatacga aagagccagg agtgttgatg ggaggtcaaa gtgagtctgt tgaatttact
    33241 aaagacactc aaacaggcat gagcggtttc agtgaaacag tgaccattgt tgaagatacg
    33301 cgtccgaagt tagtgttcca ttttgacaat aatgagccca aagtggaaga gaatcgggaa
    33361 aagcctacaa aaaatataac acctatcctt cctgcaacag gagatattgg aaatgttttg
    33421 gcctttcttg gaatccttat tttgtcagta ctttctattt ttagcctttt aaaaaacaaa
    33481 caaaacaata aagtctgacg taaaagtgtt ccataagaaa taatgcgcaa atatgctgaa
    33541 tagtggataa ctgctacagt caagacaagt gttaattcaa aaggtactac ttatacatct
    33601 gataataata aggtgacaga taattcagag caagtaggat ggctaaaaaa tgatgtattc
    33661 tatgtataat agacttacaa gaaatcaagt tattgttaaa cgtcgtaaag cttaacgctt
    33721 tcaaaagtcg aaatcaatcg agactgtctt taggcagtct cgatttttat tgataaggaa
    33781 ctgcaatgac agaaagacta aaaaatctag ggatactctt attattttta ttgggaacag
    33841 ccatttttct ttaccctacg ctaagtagtc agtggaatgc ctatcgtgat cgtcaattgt
    33901 tatcaactta tcacaaacaa gtgactcaaa agaagccctc agaaatggag gaggtgtggc
    33961 aaaaggctaa ggcgtataac gctaggcttg ggattcagcc cgttccagat gttttttcat
    34021 ttagggatgg cattcatgac aaaaattacg aaagcctact tcaaattgaa aacaatgata
    34081 ttatgggata tgttgaagtg ccctctatta aagtgacgtt acccatatac cactatacga
    34141 cagacgaggt gctaactaag ggagcaggtc acttagttgg aagtgcctta ccagttggtg
    34201 gcgacgggac tcacacggtt atttctgctc atagaggcct tccatcggca gaaatgttta
    34261 ctaatttgaa tttagtgaaa aggggagata ctttttactt tcgtgtgtta aataaagtat
    34321 tggcttataa agttgatcag atactaactg ttgaaccaga tcaagtcaca tctctttctg
    34381 aggtaatggg aaaagattat gctactctgg ttacctgcac acaatatggt gttaatacca
    34441 agcgtctatt ggtcagaggt catagaattg catttcatta caaaaagtat caacaggcta
    34501 aaaaagcaat gaaactcgtg gataaatcaa gaatgtggac agaagtagta tgtgctgctt
    34561 tcggggtggt tatagctatt attttagtat ttatgtattc aaagatgact gataaaaaag
    34621 tgattaaaaa ctaacttgcc ctgaatcttc attatcgtac tgaaactgtc gtaaaagtaa
    34681 aataatctgg tagttactat cccctttgat gaagtttaat taaatctcat caagagaaaa
    34741 atattaggcg gttacaaatg attttcccaa aaattatttt ttggaacgca taatatggaa
    34801 aaaaagatga taagaacaac tgttttaaac atcaaataaa tgatatagta gctatgaaat
    34861 agcattgtga ctgtccggta aagggatggg actgaagatt ttattcagaa ggagagggaa
    34921 tgaataacaa aaaattgcaa aagaagcaag atgctcctcg ggtatcaaac agaaagccaa
    34981 aacaattaac tgtcacttta gtgggagtat ttttaatgct cttagtattg ataggatttg
    35041 aaggaaaagt tcgagcagct cacgaattgg ttgaggtacc agtacctatt tttcacaatc
    35101 cagatccaca gtcagactat cagtggtatg gctatgaagc ctatacaggg gggtatccga
    35161 agtatgattt attcaagaca tactatcatg atctgagagt gaatttgcat gggagtaaaa
    35221 gttatcaagt atattgtttt aacgttcaca aacactatcc tcgtccctcc cagagttttg
    35281 atcggaagtg gtataaaaaa ttagatggaa ctgctgagaa ttttgattct cttgctatgg
    35341 aaccaagagt tcgtaaagag gagttaacca aaaaactccg agctgttatg tataatgcct
    35401 atcctaatga tgctaatggc attatgaaag atttagagcc tttaaatgct attaaagtca
    35461 ctcaagaagc tgtatggtac tattcggaca attctcctat taacccagat gaaagtttta
    35521 aatctgaagc tctggctaat aaaattagtg ctacacaaat atctttaatg agagaggctt
    35581 tgaagcaact tattgctcct gatttagatg agaagcaatc taggagagtt cctgatggat
    35641 atcagttgag tatttttgaa tctgagaata aggattatca aaatcttttg gctgcagaag
    35701 aggttcctat tcaacctcca aaaccggggg ataagccacc actaccgcca gtgcaaacaa
    35761 aacaaacatc agtcattatc agaaaatatg cggaaggtga ctactctaaa cttctagagg
    35821 gagcaacctt aaagcttgct caaattgaag gaagtggttt tcaggagaaa atttttgata
    35881 gtaacaagtc tggagagaaa gtagagctac ctaatgggac ttacgtttta agtgagctaa
    35941 aacctcctca aggatatgga gttgccacac ccattacttt taaagttgca gctgggaaag
    36001 ttttaataaa aaataaagaa ggtcaatttg tagagaacca aaataaggaa atcgcagagc
    36061 catattctgt aacagctttc aatgactttg aagagattgg ttatttatct gattttaata
    36121 actatggtaa gttttactat gcaaaaaata ctaatggaac taatcaagtt gtctactgtt
    36181 tcaatgctga tttacactca ccacctgact catatgatca cggagcaaat attgatcctg
    36241 atgttagtga aagtaaagag ataaagtata cacatgtttc tggctatgat ttgtataaat
    36301 atgcagtcac accaagagac aaagatgctg atttattctt aaaacatatc aagaaaattc
    36361 ttgataaagg ttataagaag aagggggata cctataagac attaactgaa gctcagttta
    36421 gagcagcaac tcaattagct atttattact atacagatag tgctgattta acaacactta
    36481 agacatataa tgataacaag ggttatcatg gttttgataa actggatgat gcaacattag
    36541 ctgtggttca tgagttgatc acctatgctg aggatgtcac cttaccaatg actcaaaatc
    36601 tagatttctt tgttcctaat agcagtagat accaggcact tattggaacg cagtatcatc
    36661 caaatgaatt gattgatgtt atttctatgg aagataaaca ggctcctatt attcctatta
    36721 ctcacaagtt aactatttct aaaactgtta ctggaactat tgcagataag aaaaaagaat
    36781 ttaactttga aatacattta aaatcttctg atggacaagc tataagtgga acatatccga
    36841 caaactctgg agaactcaca gttacagatg gaaaagctac cttcacatta aaggatggag
    36901 aatcattgat tgttgagggg ctaccttcag gttactctta tgaaattacc gaaacgggtg
    36961 cttcagatta tgaggtaagt gttaatgggc agaatgtacc tgatggaaaa gtgatgaaag
    37021 aactagttaa ggaagatgag actgtagctt ttgaaaaccg aaaagatctt gtcccaccaa
    37081 ctggtttgac aacagatggg gctatctatc tttggttgtt attacttgtt ccatttgggt
    37141 tattggtttg gctatttggt cgtaaaggga ctaaaaaatg actaattacc taaatcgctt
    37201 aaatgagaat ccactattta aagctttcat acggttagta cttaagattt ctattattgg
    37261 atttctaggt tacattctat ttcagtatat ttttggtgtc atgattatta acactaatga
    37321 tatgagtcct gctttaagtg caggtgacgg tgttttatat tatcgtttga ctgatcgcta
    37381 tcatattaat gatgtggtgg tctatgaggt tgataacact ttgaaagttg ggcgaattgc
    37441 cgctcaagct ggcgatgagg ttagttttac gcaagaagga ggactgttga ttaatgggca
    37501 tccaccagaa aaagaggtcc cttacctgac gtatcctcac tcaagtggtc caaactttcc
    37561 ctataaagtt cctacgggta cgtatttcat attgaatgat tatcgtgaag aacgtttgga
    37621 cagtcgttat tatggggcgt tgcccatcaa tcaaatcaaa gggaaaatct caactctatt
    37681 aagagtgaga ggaatttaaa aaaatttgga gagagaaaaa atgaaaaaaa acaaattatt
    37741 acttgctact gcaatcttag caactgcttt aggaacagct tctttaaatc aaaacgtaaa
    37801 agctgagacg gcaggggttg ttagcagtgg tcaattaaca ataaaaaaat caattacaaa
    37861 ttttaatgat gatacacttt tgatgcctaa ggctacattt acctttgacg ttaaaccggt
    37921 tgatgtaaca ggagaagaaa aggatacagc ttcaggctta aagattcaaa aaggtattgc
    37981 tggagtagca tcgcagacaa tccaatacga taatactgat aagccaacga acaaagagaa
    38041 ggcagtaaac tttgattttt ctacagtaac ttttccaaac gtaggggttt accgatatga
    38101 agtttcagaa caagctggtg acgtgaaggg gattacttat gattctaaaa agtggacagt
    38161 agatgtctat gtagtaaatg aaaataacaa gttcacacct aaatatatcg tctcaaaaga
    38221 aaccacagac tcaagcaaaa aaccgattgt ctttaataat gagttaaaaa caacttcttt
    38281 aactatcaaa aaagaagtta cgggaaacag tggagataaa acaagtgatt ttacatttac
    38341 tctcctcttg aaagaaaata ctcagtttga aacaggtcag aaagtcaagg ctactaagaa
    38401 gaagtctggt gctgaagaag aaacagtaga agtcacaatt ggtaagcaat atacctttac
    38461 tttgaaagat agtgaggagc tgatactaga taaattaccg attggtatta cctatcaggt
    38521 agatgagact gataaaaata aggaacagta tgaaacatcc gcaaagatga cagaagattc
    38581 gaaagaagca caaggctata cgttaaatga tttaaaaaca acagatgaga ctgctgatac
    38641 aatcactgtt accaataaga gaaacttgcc tatcccaact ggtgttgtag gcatccttgc
    38701 tccatttgca gttcttagca ttgtggctat tggtggagtt atctatatta caaaacgtaa
    38761 aaaagcttaa gtgattagtc aaagaatgat gatgacaatt gtacaggtta tcaataaagc
    38821 cattgatact ctcattctta tcttttgttt agtcgtacta tttttagctg gttttggttt
    38881 gtgggattct tatcatctct atcaacaagc agacgcttct aatttcaaaa aatttaaaac
    38941 agctcaacaa cagcctaaat ttgaagactt gttagctttg aatgaggatg tcattggttg
    39001 gttaaatatc ccagggactc atattgatta tcctctagtt cagggaaaaa cgaatttaga
    39061 gtatattaat aaagcagttg atggcagtgt tgccatgtct ggtagtttat ttttagatac
    39121 acggaatcat aatgatttta cggacgatta ctctctgatt tatggccatc atatggcagg
    39181 taatgccatg tttggcgaaa ttccaaaatt tttaaaaaag gattttttca acaaacataa
    39241 taaagctatc attgaaacaa aagagagaaa aaaactaacc gtcactattt ttgcttgtct
    39301 caagacagat gcctttgacc agttagtttt taatcctaat gctattacca atcaagacca
    39361 acaaaggcag ctcgttgatt atatcagtaa aagatcaaaa caatttaaac ctgttaaatt
    39421 gaagcatcat acaaagttcg ttgctttttc aacgtgtgaa aatttttcta ctgacaatcg
    39481 tgttatcgtt gtcggtacta ttcaagaata acgaaaggag gagacttttg agaaaatatt
    39541 ggaaaatgtt attttctgtc gtaatgatat taaccatgct ggcctttaat cagactgttt
    39601 tagcaaaaga cagcactgtt caaactagca ttagtgtcga aaatgtctta gagagagcag
    39661 gcgatagtac cccattttcg gttgcattag aatcaattga tgcgatgaaa acaatagaag
    39721 aaataacaat tgctggttct ggaaaagcaa gcttttcctc tctgaccttc acaacagttg
    39781 ggcaatatac ttatcgtgtt tatcagaagc cttcacaaaa taaagattat caagcagata
    39841 ctactgtatt tgacgttctt gtctatgtga cctatgatga agatgggact ctagtcgcaa
    39901 aagttatttc tcgaagggct ggagacgaag aaaaatcagc gattactttt aagcccaaac
    39961 ggttagtaaa accaataccg cctagacaac ctgacatccc taaaacccca ttaccattag
    40021 ctggtgaagt aaaaagttta ttgggtatct taagtatcgt attactgggg ttactagttc
    40081 ttctttatgt taaaaaactg aagagtaagc tataaaaccc atttttaaga gtcacacatt
    40141 tttagttgct ctatttttat aatgaaactt attgacatct ccatagtctt gcttgacttt
    40201 ggagatgttt tctatgctga taggtttttg taccatataa gacaatgatt gatgaaaaga
    40261 gtgtcttgaa ttcttaaata ttatctcggt atttagcaag atagtctttt gaagaaatac
    40321 ccgtgtattt tttaaagatt ttatgaaaat gggtagtgtc ataaaaatat aagcttttag
    40381 ccacttctcc aacaggaatt cctcgtttta agagtagttg agcttctttg atttttgtac
    40441 ttagaatata atgttgtaag gaaatatttg agtatttttt aaagactgaa cgtaagtgag
    40501 attcggaaac atataggcgc ttagcgatat cagatacctt taatttggaa tacaggtgac
    40561 tatcgacata atgaagcaca ctattgtaca tttgacgttt atcagaaata cttttattgg
    40621 ttaatgattc ggaaaaatgg atgatagctg cacagcgaat tctcaaaact ttgagcaagt
    40681 cactcgcttc ttcatttaag gccatgtagt atttgacaag gctataatgc tttgctacgt
    40741 cagtattttc tacaaaactg aattccagta acctagttaa atagataaca gtgaggttct
    40801 tttccgccct tagagcagaa atagaagatg aggtgatact tgataagggg atacgattga
    40861 tttcttgctt gagcaattgt ggattgccta gctttaccag atccataata tgatttaggt
    40921 gctctaaaac aggcggtaat tggctagatg ctttgctaat atgcttaagg cgatgaatga
    40981 tatcaggatc agcagtcatc tgttttgaat gctgcaacaa ttgatgaatt gtttgttggc
    41041 aagtcgtctc aaattgtgtg tcaaaaaaag cgtcaatagc tatcaaaagg ttccgcacat
    41101 tattaattgg aaaatgtggg acaagtgcca tataggataa gagctcttct ttgctacgat
    41161 gagaagaatg ttttaaaaaa ttattagcta attgttcctg atagtcttta ttaagtgaat
    41221 aagggtagaa aggtccaatg gcaataatgt agtgacaaag aggaaaaatc ataaaggact
    41281 cttcaaataa accctcataa aaaataacat cttgtgtggc ttgaggaata gctagatgct
    41341 ttaaaaattg atagtaacat aataaatagt cgtcattacc atatacttga ataagtgcct
    41401 tatcttgtga catcactgaa ataggtaatt gagacaagct gtgtaatgtt tgcacatgtt
    41461 ttaaatcgaa tataaccatt tgatagattg ccccccatcc ttagttgtat cattttcctt
    41521 agacttgtaa aagctttagt aaatgttaat gatgaaaatt cctatttggt aggcacacta
    41581 aaaggtcttc ctaatagtaa actctctctc catcatctcc tgccttaatt atactatgaa
    41641 tagctaagca gataaagata aaggacttgt acgttaagcg cttgaaaaag aaagagttac
    41701 agataatgac ataaaaaacg ctaaaaaacc atcaaaataa atactctaac cataagatgt
    41761 agacttgaca actgaaaatg gtaatggtaa aataactatt tgacagttgt cctgtagtct
    41821 ttagttttgg acataggctg tcgcttatga atgtggagag agaaaataaa tgacacaaaa
    41881 aaatagctat aagttaagct tcctgttatc cttaacagga tttattttag gtttattatt
    41941 ggtttttata ggattgtccg gagtatcagt aggacatgcg gaaacaagaa atggagcaaa
    42001 caaacaagga tcttttgaaa tcaagaaagt cgaccaaaac aacaagccct taccgggagc
    42061 aactttttca ctgacaccaa aggatgggaa gggaaaacct ggtcagacat tcacttcaaa
    42121 tgataaaggt attgtagatg ctcaaaatct ccaaccaggg acttatacct taaaagaaga
    42181 aacagcacca gatggttatg ataaaaccag tcggacttgg acagtgactg tttatgagaa
    42241 cggctatacc aagttggttg aaaatcccta taatggggaa atcatcagta aagcagggtc
    42301 aaaagatgtt agtagttctt tacagttaga aaaatcaaca atgtctgttg tatccaagta
    42361 cggtgaacag gaaaaaacat caaacttagc ggatttctac cgtaaccatg ccgcctattt
    42421 taaaatgtct tttgagttga aacaaaagga taaatctgaa acaatcaacc caggcgatac
    42481 ctttgtgtta cagctggacc aacgtctcaa tcctaaaggt atcagtcaag atatccctaa
    42541 aatcatttat gacagtgcaa atagtccgct tgcgattgga aaatacgatg ccgatagcca
    42601 tcaacttatc tatactttca cagattatat tgcaggttta gataaagtcc ggttgtctgc
    42661 agaattgagc ttattcctag agaataagga agtgttagaa aacaccaaca tttcagattt
    42721 taagagtacc ataggtgggc aggagatcac ctataaagga acggtcaatg ttatctatgg
    42781 gaataaatcg ggagacagca ataattatgt taagaatata ttgagcaatg tgggtggaag
    42841 tattgaaagc tacaatacac aaacaggcga ctttacttgg tatgtttatg tcaatcctaa
    42901 aaagcaatct atcaactatt ctatcctaaa tttatgggga tttggaaggg ctcgttcaaa
    42961 cacaaacaac ttagaaacaa atgctaatac aagtagtgcc caattggaaa aagtagaaat
    43021 ttatgaagtt aaagaggact atacgctacc tactagctat ggggttgata ttacaaaact
    43081 tactttaaga acggatatca cagtggggaa taaagatggt tttccaatga ctaaacgtca
    43141 gcggattgat tttaaagata atcttaaaga tggaaaaagg tttgttgtta aagtaacagg
    43201 gaaaacagac caatctggta agccactagt cgttcaatcc aatttagcca gtttttcaac
    43261 taatcaagat tatgttgact taaaaataag tggagggaat gtctacttcc aaaacgaaat
    43321 tgccttgtct ccttctaagg gtagtggttc tgggaaaagt gaatttacta agccctctat
    43381 tacagtagca aatctaaaac gagtggctca gcttcgcttt aagaaaatgt caactgacaa
    43441 tgtgccattg ccagaagcga cttttgagct gcgctcatca actagtgaca gtcaaaaagt
    43501 agaagcaaaa tcaaatgaac aaggagaggt tcactttaag gacctgaatt cgggcaccta
    43561 tgacttgtat gaaaaacaag cacctaaagg ctatcagcag gtgacagaga aattggcgac
    43621 cgttactgtt gatactacca aacctgctga ggaaatggtc aagtgggaaa agacacatcc
    43681 gtttgtaaaa gtagaagtta acaaagaagt cacgattgtc aaccataaag aaacccttac
    43741 gttttcaggg aagaaaattt gggagaatga cagaccagat caacgcccag caaagattca
    43801 agtgcaactg ttgcaaaatc gtcaaaaaat gtccgataaa gttcaagaag taacgaagga
    43861 taacgattgg tcttatcact tcaaagactt gcctaagtac gatgacaaga atcaggagta
    43921 taagtactca gttgaagaag taaaagttcc agacggctac aaggtgtcgt atttaagaaa
    43981 tgatatattt aacaccagag aaacagaatt tgtgtttgaa cagaataact ttaaccttga
    44041 atttggaaat gctgaaataa aaggtcaatc tgggtcaaaa atcattgatg aagacacgct
    44101 aacgtctttc aaaggtaaga aaatttggaa aaatgatacg gcagaaaatc gtccccaagc
    44161 cattcaagtg cagctttatg ctgatggagt ggctgtggaa ggtcaaacca aatttatttc
    44221 tggctcaggt aatgagtggt catttgagtt taaaaacttg aagaagtata atggaacagg
    44281 taatgacatc atgtactctg ttaaagaagt aactgttcca acaggttatg atgtgactta
    44341 ctcagctaat gatattatta ataccaaacg tgaggttatt acacaacaag gaccgaacct
    44401 agagattgaa gaaatgcttc cgctagaatc aggtgcttca ggtggtacca ctactgtcga
    44461 agactcacgc ccagttgata ccttgtcagg tttatcaagt gagcaaggtc agtccggtga
    44521 tatgacaatt gaagaagata gtgctaccca tattaaattc tcaaaacgtg atattgacgg
    44581 caaagagtta gctggtgcaa ctatggagtt gcgtgattca tctggtaaaa ctattagtac
    44641 atggatttca gatggacaag tgaaagattt ctacctgatg ccaggaaaat atacatttgt
    44701 cgaaaccgca gcaccagacg gttatgagat agcaactgct attaccttta cagttaatga
    44761 gcaaggtcag gttactgtaa atggcaaagc aactaaaggt gacgctcata ttgtcatggt
    44821 tgatgcttac aagccaacta agggttcagg tcaggttatt gatattgaag aaaagcttcc
    44881 agacgagcag ggccattctg gctcaactac tgaaatagaa gatagcaagt cttcagacgt
    44941 tatcattggt ggtcaggggc agattgtcga gacaacagag gatacccaaa ctggcatgca
    45001 cggggattct ggttgtaaaa cggaagtcga agatactaaa ctagtacaat ccttccactt
    45061 tgataacaag gaatcagaaa gtaactctga gattcctaaa aaagataagc caaagagtaa
    45121 tactagttta ccagcaactg gtgagaagca acataatatg ttcttttgga tggttacttc
    45181 ttgctcactt attagtagtg tttttgtaat atcactaaaa actaaaaaac gcctatcatc
    45241 atgttaagat aagctgttgg tgacaatagc gaaaaagggt ccacttgtta gtggacctct
    45301 ttttctggaa tcgatcgtct cggttcacta gataagtcat tttaagtagt caaaataggc
    45361 agagccttaa aaggttttct gcctttttaa tcttgttggg cacttacgaa agtatttcgg
    45421 ccacttcaag cataataaaa agagtctgag caatcatgtt gtctcagact ctgactgtaa
    45481 ttatgcaaaa gatgatggac tggcagcttc atttactcac cgaactcccc tttataactt
    45541 gggaatgatg ctgctaatgg gttattttgt ttaatacctg ctataaacgg taatttattc
    45601 catttatctt tgtaaccttc ttcaagctca gttttaaact tccaaaccat tttatgagaa
    45661 aaataagtgt gtgattgacg gccgtaggtg tctactaaaa cgtgagaaaa ttttccgtcg
    45721 ttttttagtt tgtaaaattt atctagagaa ggactccaac cagtataacc agggaattta
    45781 tcaaattctt gattaaaatt tgttttttgg ttttcccaat cataatgcca ttgtgtatta
    45841 ctgcgtgttt tagaatcaac tgtaccgtcc caataatgat gctcataagt tatctcctta
    45901 ggagctttta cacccttagg aagaaacact gagaaatcag ggtaaaccca ttgttcttta
    45961 gctgaattaa aggttacagt ccattcgata ctgttattgt tatcgaccaa tgttttagta
    46021 tagtcgacat agttatcaac atagtaattt ccctgccagt aaaggtgcac tttacctttc
    46081 tcatcaatgt tatcatgggc atgtactgat ttatatgaac taaacagaat cgaaactgct
    46141 agtagtgaag tgaagagata tttattacat cgtttcatat catgaaaaac ctttc
//
LOCUS       DAUGOH010000013        44565 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUGOH010000013 DAUGOH010000000
VERSION     DAUGOH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44565
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.013"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            22..309
                     /locus_tag="VH957_000746"
     CDS             22..309
                     /locus_tag="VH957_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HEQ8558674.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            299..634
                     /locus_tag="VH957_000747"
     CDS             299..634
                     /locus_tag="VH957_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8558675.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQHKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKISHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     RSDYIKLFK"
     gene            786..1256
                     /locus_tag="VH957_000748"
     CDS             786..1256
                     /locus_tag="VH957_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8558676.1"
                     /translation="MEEFTKPTHKTYSEIFEKWYQAYHDTVEPTTASRTLDLFRLHIL
                     PVMGELPINKTSPLDCQKFITDKAKTFKNIKQIKSYTEKVFDFAIKMKLLKHNPMAEI
                     IMPKRKKIRIENYWTVQELQEFLAIVLQKEPYKHYALFRLLAYSGLKERRAMRS"
     gene            1219..1767
                     /locus_tag="VH957_000749"
     CDS             1219..1767
                     /locus_tag="VH957_000749"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8558677.1"
                     /translation="MAALRKGELCALKWVDIDFQSETLSVNKSLGRLDGKTIEKSTKN
                     DFSVRKIKLDSETISILQEWKAVSQKEKTQLAVAPLSIKSDFIFTYCTREGSIEPLHA
                     DYINNILSKVIKQHSLKKISPHGFRHTHATLMIEIGVDPVNTAKRLGHASSQMTLDTY
                     SHATAVGEDKSIKQFANYLKNN"
     gene            complement(1899..2291)
                     /gene="rpsI"
                     /locus_tag="VH957_000750"
     CDS             complement(1899..2291)
                     /gene="rpsI"
                     /locus_tag="VH957_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEQ8558678.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2312..2758)
                     /gene="rplM"
                     /locus_tag="VH957_000751"
     CDS             complement(2312..2758)
                     /gene="rplM"
                     /locus_tag="VH957_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEQ8558679.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(2976..3182)
                     /locus_tag="VH957_000752"
     CDS             complement(2976..3182)
                     /locus_tag="VH957_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8558680.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(3179..3685)
                     /locus_tag="VH957_000753"
     CDS             complement(3179..3685)
                     /locus_tag="VH957_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558681.1"
                     /translation="MFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGG
                     VAFVLTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLSMGASIFYRHY
                     LDAKEADE"
     gene            complement(3821..4681)
                     /locus_tag="VH957_000754"
     CDS             complement(3821..4681)
                     /locus_tag="VH957_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8558682.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHAKNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(4778..5296)
                     /locus_tag="VH957_000755"
     CDS             complement(4778..5296)
                     /locus_tag="VH957_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEQ8558683.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            complement(5300..6046)
                     /gene="rlmB"
                     /locus_tag="VH957_000756"
     CDS             complement(5300..6046)
                     /gene="rlmB"
                     /locus_tag="VH957_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEQ8558684.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKSRGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(6093..6890)
                     /locus_tag="VH957_000757"
     CDS             complement(6093..6890)
                     /locus_tag="VH957_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558685.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQTNQSANQEIDSTSNPFRSATNHRSTSLKRSTKNEKLTSTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLLGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(7086..7499)
                     /locus_tag="VH957_000758"
     CDS             complement(7086..7499)
                     /locus_tag="VH957_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEQ8558686.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(7492..8835)
                     /locus_tag="VH957_000759"
     CDS             complement(7492..8835)
                     /locus_tag="VH957_000759"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEQ8558687.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEAAGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKLAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFVNYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKALHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            complement(8863..9093)
                     /locus_tag="VH957_000760"
     CDS             complement(8863..9093)
                     /locus_tag="VH957_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558688.1"
                     /translation="MNKIRVGLYVIMSLSILVFSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(9571..10152)
                     /gene="cysE"
                     /locus_tag="VH957_000761"
     CDS             complement(9571..10152)
                     /gene="cysE"
                     /locus_tag="VH957_000761"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEQ8558689.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTIRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(10161..10913)
                     /locus_tag="VH957_000762"
     CDS             complement(10161..10913)
                     /locus_tag="VH957_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEQ8558690.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSVALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQESAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(10906..13038)
                     /gene="pnp"
                     /locus_tag="VH957_000763"
     CDS             complement(10906..13038)
                     /gene="pnp"
                     /locus_tag="VH957_000763"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEQ8558691.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIIAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASIKALIPRPPKPEKKEEKHD"
     gene            complement(13318..14049)
                     /locus_tag="VH957_000764"
     CDS             complement(13318..14049)
                     /locus_tag="VH957_000764"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEQ8558692.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDAKH"
     gene            complement(14059..15438)
                     /locus_tag="VH957_000765"
     CDS             complement(14059..15438)
                     /locus_tag="VH957_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEQ8558693.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLTFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVIFYLVATVASVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQE
                     AINNVSEEI"
     gene            complement(15465..15749)
                     /locus_tag="VH957_000766"
     CDS             complement(15465..15749)
                     /locus_tag="VH957_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8558694.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKDADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            complement(15742..17802)
                     /locus_tag="VH957_000767"
     CDS             complement(15742..17802)
                     /locus_tag="VH957_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8558695.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVISGSWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKKQIKQDYESLFYLVKRSLSPLEKQLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSEWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGARQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(18154..18423)
                     /gene="rpsO"
                     /locus_tag="VH957_000768"
     CDS             complement(18154..18423)
                     /gene="rpsO"
                     /locus_tag="VH957_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEQ8558696.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(18599..18799)
                     /locus_tag="VH957_000769"
     CDS             complement(18599..18799)
                     /locus_tag="VH957_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558697.1"
                     /translation="MTMLGYRLSAEVLGSAILPLLAGYLIRQAIAQVYSDLKTAFWLF
                     GLASSVAYGGLVKAKRAHSMTR"
     gene            18925..19182
                     /locus_tag="VH957_000770"
     CDS             18925..19182
                     /locus_tag="VH957_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8558698.1"
                     /translation="MTQNVCQQNITYTVKERFASYILKAQANQEVHLNFTLLANRFGI
                     SDRHLKHVLKQLIFQRIIERICFKTCRIADLDALTQLSVNN"
     gene            19308..19922
                     /locus_tag="VH957_000771"
     CDS             19308..19922
                     /locus_tag="VH957_000771"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8558699.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(19955..20497)
                     /locus_tag="VH957_000772"
     CDS             complement(19955..20497)
                     /locus_tag="VH957_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8558700.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(20628..21056)
                     /locus_tag="VH957_000773"
     CDS             complement(20628..21056)
                     /locus_tag="VH957_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8558701.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(21166..25563)
                     /locus_tag="VH957_000774"
     CDS             complement(21166..25563)
                     /locus_tag="VH957_000774"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEQ8558702.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLTRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRKNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKAAITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVVPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     ILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEIGILGNMPEDNQLSLFDDFF"
     gene            complement(25817..27673)
                     /locus_tag="VH957_000775"
     CDS             complement(25817..27673)
                     /locus_tag="VH957_000775"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEQ8558703.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRNAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTKSSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            complement(27871..29130)
                     /gene="rseP"
                     /locus_tag="VH957_000776"
     CDS             complement(27871..29130)
                     /gene="rseP"
                     /locus_tag="VH957_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEQ8558704.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHT
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(29203..29997)
                     /locus_tag="VH957_000777"
     CDS             complement(29203..29997)
                     /locus_tag="VH957_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEQ8558705.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(30010..30759)
                     /locus_tag="VH957_000778"
     CDS             complement(30010..30759)
                     /locus_tag="VH957_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEQ8558706.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            complement(30975..31340)
                     /gene="yajC"
                     /locus_tag="VH957_000779"
     CDS             complement(30975..31340)
                     /gene="yajC"
                     /locus_tag="VH957_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEQ8558707.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(31456..31830)
                     /locus_tag="VH957_000780"
     CDS             complement(31456..31830)
                     /locus_tag="VH957_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEQ8558708.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKDVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            complement(31945..35442)
                     /locus_tag="VH957_000781"
     CDS             complement(31945..35442)
                     /locus_tag="VH957_000781"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEQ8558709.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSDDGFQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLGFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAQYPYFIHDSYDSSDAVNHFDWAKATDSRAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDSSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            complement(35640..37253)
                     /locus_tag="VH957_000782"
     CDS             complement(35640..37253)
                     /locus_tag="VH957_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEQ8558710.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTNGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEDLRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTKLKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFAKDLAGAQ
                     VIITNTDVDTVLETKHLQPWDAFCLKLKA"
     gene            complement(37383..38516)
                     /gene="ugpC"
                     /locus_tag="VH957_000783"
     CDS             complement(37383..38516)
                     /gene="ugpC"
                     /locus_tag="VH957_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEQ8558711.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(38814..39662)
                     /locus_tag="VH957_000784"
     CDS             complement(38814..39662)
                     /locus_tag="VH957_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEQ8558712.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPADLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAH
                     LFLLKY"
     gene            40003..41325
                     /gene="ska"
                     /locus_tag="VH957_000785"
     CDS             40003..41325
                     /gene="ska"
                     /locus_tag="VH957_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEQ8558713.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSQPAQGGKTEQDLNPKSKPLATDKGAMSHKLEK
                     ADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKAVHNSAERVNVNYEVSFVSETGGLDFTPLLRNQYHLTTLAVGD
                     SLSSQELAAIAQFILSKKYPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYEINPKTGIKEKMNNTDLISEKYYVLKKGEKPYDPFDRSHLKLFTINYVDVNTNELL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDDTNRIIT
                     VYIGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK"
     gene            complement(41423..41863)
                     /locus_tag="VH957_000786"
     CDS             complement(41423..41863)
                     /locus_tag="VH957_000786"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEQ8558714.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLVGVGPDDNAEDLAYA
                     VRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLAS
                     QLYDSFNEQLAEFVPVERGVFGADMQVSLVNDGPVTIILDTKCH"
     gene            complement(41878..44097)
                     /locus_tag="VH957_000787"
     CDS             complement(41878..44097)
                     /locus_tag="VH957_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEQ8558715.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            complement(44349..44459)
                     /locus_tag="VH957_000788"
                     /pseudo
     CDS             complement(44349..44459)
                     /locus_tag="VH957_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_129544913.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        13064 a         9934 c         8424 g        13143 t
ORIGIN      
        1 tacataaagg ggttacataa aatgactaca gtaaaaaaaa acagagcggt tacctttcaa
       61 gctaataaag aattggtaag cgaagcaatg acagtattaa acaaaaaaaa tttaacctta
      121 tcatctgctt taagattatt cctacaaaat gtcgttgtca caaacgaggt tgacttattg
      181 acggaagagg agttagagaa agaaaaactt ttcaagcaat ttcaagctga aatcaacaaa
      241 aatattgagg atgttcgtca agggaagttt tatacctctg aagaagtgag ggctgaactt
      301 ggactataag aaatatcaga ttatctatgc tcctgatgtt ttagagaagc taaaagaaat
      361 tcgtgattat atttctcaaa actattcctc aacatcaggt cagcataaaa tggagcaaat
      421 cattagcgac atagaaaaac tcgaggtttt cccagaagtt ggttttgatg ctgatgaaaa
      481 atatggttca aaaatcagcc attatcacag cactaaaggt tacaccttaa gtaaagatta
      541 tattgtccta taccatatcg agggggaaga aaatagggtc gttattgatt acttgcttcc
      601 tactcgaagc gactatataa agttattcaa ataacacgtt aaaagcctta gcagtcttgc
      661 tagggctttt ttggtagatt acaaattaac taggagcaaa atgagttcgg gctgtttagt
      721 agatattcca caaagaagcc aaagactacg aagctaggct aatctacctt aaggcttcag
      781 gaaacttgga ggagttcacc aagccaactc ataaaactta tagcgagata ttcgagaaat
      841 ggtatcaagc ctatcatgat acggtagagc caaccacggc ttctcgtact cttgatctgt
      901 ttcgacttca cattttgcca gtcatgggag aattgcccat taacaaaacc tcccctttag
      961 actgccagaa attcatcacc gataaagcaa agacctttaa gaatatcaag caaatcaagt
     1021 cctacactga aaaggtcttt gattttgcca tcaagatgaa actgctcaag cataacccta
     1081 tggctgaaat cattatgcca aagcggaaaa aaatacggat agaaaactat tggacggttc
     1141 aagaacttca ggagttttta gccatagtac ttcagaaaga gccttacaag cactacgcac
     1201 tatttcggct actagcttat agcggcctta aggaaaggcg agctatgcgc tcttaaatgg
     1261 gttgatatag actttcagag tgagacacta agcgtcaata agagcctagg acgattagac
     1321 ggaaagacaa tcgaaaaaag cactaaaaat gatttctcag taagaaagat taagctagac
     1381 agcgaaacta tttctattct gcaagaatgg aaagccgtca gccaaaaaga aaagacacaa
     1441 ctagcagttg cacctctttc aattaagtct gactttatat ttacatactg tactagagaa
     1501 gggagtattg aaccacttca tgcagactat attaacaata tcttatcaaa ggtcattaag
     1561 caacatagtc ttaaaaaaat aagtcctcac ggcttcaggc atacccatgc aaccctgatg
     1621 attgagattg gagttgaccc agtaaataca gccaaaaggt taggacatgc tagtagtcaa
     1681 atgactcttg atacatacag tcatgctact gcagtcggag aagacaaatc aatcaaacaa
     1741 tttgctaact atctcaaaaa taactaaata aacgtattaa accaagtcaa aagttttccg
     1801 aaacggtatc aaaaaaggta tcaaaagcaa aaaacgacaa aaaaagcacc ttgcaagaga
     1861 cttgcaaaat gcttgtaatc gttgatgtaa agctgttctt aacgttttga gaattgtgaa
     1921 gctttacgag ctttcttaag acctggtttt ttacgttcaa ccatacgtgc gtcacgtgta
     1981 agaaggccag cgcgtttcaa tgaatcgcgg aagtctgggt ctacttgaag aagcgcacga
     2041 gcgataccat gacggatcgc acctgattgt ccaccgtaac caccaccaac aacgttaacg
     2101 aaaacgtcgt atgaaccttc agttgatgta actgcaaaag gttggttgat gatcaaacgt
     2161 aagtcagcat gtgggatgta ttcttctaca tcttttttgt taacagtgat tttaccagta
     2221 cctggaacca aacgaacgcg tgcaacagcg tttttacgac ggccagtacc tgcatattgt
     2281 gcttgtgcca ttatttaatg ctcctttcct cttagataag tcctgagatg tcaagtactt
     2341 ctggttgttg tgctgcgtga gtatgctcac cgccaacgaa gactttcaat ttcatacctt
     2401 gtgcacgtcc aagagtgtta tgtggaagca tgcctttaac tgatttttca atcaagcgaa
     2461 ctgcgttttt agagcgaagt tcaccagcag tgattgattt caaaccacct gggtacattg
     2521 agtgagtgta gtaaacttta tcagttgctt ttttaccagt taatttaact ttttcagcgt
     2581 tgataacgat aacaaaatca cctgtatcag tatgtggtgt gaaagttggt ttgttttttc
     2641 cgcgaagtac gctagcaact actgcagaaa gacgtccaag tggcacatca gttgcgtcaa
     2701 caacgtacca tttgcgttca acttggcctg gtttagccat gaaagttgtt ttgttcatga
     2761 tttctcctat acgaattcgt aatatttgtt tacaaggtga tgggtgttcc gtcccatcga
     2821 aggtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc tactatgata
     2881 tcaaacttaa gaggctccag tcaagtgctt tagctgattt tattggatta ttttttcttt
     2941 cgatttagga gaatggcaga gctgctctgc tggtgttaac gagaatcatc agcttcccaa
     3001 aaaaggtcat ctaaagtctt atcaagcact cgacaaatgg caatgcaaag attaatcgtt
     3061 gggttgtaat cacctttttc aacagccgca atggtttgtc tggagacgcc taccaaatct
     3121 gctagagctt gttgagacaa atctttgcct gcacgcgctg cttttaattt gaggttcttc
     3181 attcatctgc ctctttagca tccagataat gacgatagaa aatactagct cccatactaa
     3241 ggttacaata tgtcgtttga actgccaacc ctccccaaag agccaatgta aagaggaagc
     3301 ttgcagatac cagtccctct gtgaatcggc taataaagag tgacagccag ataaccacaa
     3361 tcataaacca aaacccaata gtgtatcctt tgagaagaat ctgtttttgg cgttcatcat
     3421 atttgggcaa cttctgatcg tcccttacct tagaatctag tacttccttg ctgtctagtc
     3481 tcgtttggag ctttttcgct gtctttagcc cccataccaa caatatgaga aagctagtca
     3541 atacaaaagc tacgcctcca actaagtaac gttgaaaact ggtcttagcc agtaatgttg
     3601 ctactatcac aactagatcc atcactgctg ttatgacaat gaaaccccat tgtgacttag
     3661 cgagattttg tttgctatca aacatgattc gtttctcctt taaatcttta tatgacataa
     3721 tataaattat tttggatatt ttgtcaaata tattttacat aattgattga cttaagcagc
     3781 aaaaaaggat tgaggatttc tcttcaatcc ttataaggga ttaacgggaa ttctgcccaa
     3841 tcacaaaaac tgccagggtg ttaggaccaa cgtgagctga gataactggt cctagtggca
     3901 tcataagaac atcgctaata ttctcatgcg ccagcagctc ttctcgcaac ttttcggcac
     3961 taccctgatc gcttgtataa gagacaataa ccgtcgaatc cgcaatatct ttttccactt
     4021 gagccaccat ttctttgatg gctttttggc gtccccgaat ttttgcaatg ggcaccaatt
     4081 tcccttcctc atcaatccac aaaagaggtt tgatactggc taaactgcct agaaaagctg
     4141 aaccttttga cagacgccca ccacgcatca aatgaaaaag atcatctact aagaaatagg
     4201 tgcgcagtcg aggaatcact gcttcaacaa tatctttagt ctccagtaaa tttttgccac
     4261 tatctctggc ttctgctgct aaaatggtta gatagccttc tcctcctgca gcagccaagg
     4321 tatcaacaat ttcaatcacc gcatcgggat aatcttctcg aacaagatcg cgtgccatta
     4381 gagcgctttg ataggtaccc gataaaaccg aagaaaaagc aagataaagc agtgctttgt
     4441 tgttcttagc atgttcacga aaaaccttct caaactctcc cacattaatc tgactggttt
     4501 gaggatgact gccagctttc atctttttca aaaggtaatc actactaata cggttaggac
     4561 cgaccgtttc ataaacctct ccatcgcaca aaatcgttaa tcctataagg acaatatcat
     4621 gatcttctgc ccaggtttga ttcaaatcag cggttgaatc tgtcattatt gtaaaggtca
     4681 ttcttacttc tcctcatcca gttttttagt ttgataatca aataattatt gttttatttt
     4741 atcaaaaaaa cccgcacttg gcgagtcgta attctcatta tcgatctaac tgagacataa
     4801 aatccttcaa ttgaataagc tgtccttggt caaaaggccg cagtttaggc gttttgagat
     4861 caatatctct agacatttta tctaaatcag ctttgacagt atgaactctt tgctctaatt
     4921 ctcttgcagt gacacgaaga gctccttgag aaaaaatcgt ccattgttca tttaaatcac
     4981 tcgtagctac ttctaccata tgtatagccg tatttaactc tgctgccatg cgctcaatgt
     5041 agctatctgc tgtttcgtct tcctctgtaa ataccactga gatataatac tggtcatatc
     5101 gttgccttaa ccccggtaca tattgggcat caaaaacaca aataatatta atattctcaa
     5161 aatgggcata atgattaagt tttgttaaaa gtgtgttacg tgcctgatca agctgatttg
     5221 tcttaaacaa ctgacgggtt gattgccaaa aggcaatcat attataccca tctactaata
     5281 atatccgttt tttcataatt tagcgcctat ttcggaaaac ttcatacatg agaatagctg
     5341 ccgctacgct agcatttaag ctctgtacgt gaccattcat aggaatcgta atcatttcat
     5401 caacttgctt tttgatattg gtagagatgc ctttgccttc gttaccaatg actaaagcaa
     5461 gtttaccatt agtgttccag caatcagacg gtgttccatt catgtctgtg ccaaaaatcc
     5521 agaatcctct tgatttcaat ttatctagag tttgactaag gttagttact ctcgctatcg
     5581 gaatatgttc aacagcacct gtagacgtct ttgaaaccac tggagtcaca ccaacagaac
     5641 gatgtttagg aataatcact ccacatacat ttgtagcatc agctgtccgt aaaatcgatc
     5701 ctaaattatg aggatctgtc agaccatcta aaataagaat caaaggattt gcttcttgct
     5761 ctgctatttc gaggatctca tcaacatcag tataggcaaa agctgatact ctcagaacaa
     5821 aaccttgatg cacagctcca tcagtcattt gtgacaaggt ttttttaggc gtccatgaaa
     5881 tagcgacctt tttttgtgtc gctaagcttt tgatgttatc cactttcttt cctcttaaat
     5941 cctcttggat ataaagctta tttcctgtat ttgcttgaag gctttctgta acggcatgaa
     6001 caccatagac gatatcgttt gtttcaatag tatctttatc ttccatgagt ttattatacc
     6061 atgaatgctt caaaataaat gcatagactc ttttattttc gtctagatac tttttgaata
     6121 gctataaata aacctgcagc taaactgact actagaccta ataagaccca agggaatcct
     6181 ctttttgaag taggttttac ttcctctttg tccactagca tttttgtctt gttgctaccg
     6241 tttttttggc tattactagc agttgatgta agtttctcat ttttagtaga tcgctttaag
     6301 gaagttgatc gatgattagt agctgatctg aaaggatttg aagtagaatc tatttcttgg
     6361 ttagctgatt gatttgtttg agcttttgtg tctacatcga ccgaattcgt cgttgcttta
     6421 gaagtatcct tttgttgcat attagttggt gtttttctag ctttgttttg atcaaaatga
     6481 acagttcctg attgaccagt tactgccttt tcttgagtat gaacggtgac agttacatga
     6541 tagtcaccac tcttttgtcc agttaaatca aaccaagctg taaaacgacg ctgttgcgct
     6601 gccatagtat atacccaact attaatagta ttatcactag cgtctttaag tgttatcgtt
     6661 gcctgagttg gttgtctgac aggttgatct gtggtgactg tagcatcaat ataaggttct
     6721 gttccacgca tactggcttc aacactgacc tgactaatag ttgattcagc tataacatta
     6781 tcagtgtgct gatcttgtgc atacacagat atggctttgc cagaagtccc cagcaaacca
     6841 ataagtaaag ctagtgataa taagctaact gttttttgca tagttgtcat aataaatatc
     6901 tcctctttaa attagtctta ccctctcatt ataaactatt cgaaaatgat ttcattattt
     6961 ttatgtcttt tttgttacaa atgtatcttt tttatatcat tatgtctttt tgatgtcata
     7021 aaaagagtta atggctctct acctttactt cagacctatg aaaataagag tctcctaggg
     7081 gactcttatg aggatatcaa ttgttgcttt tctacatact caatacacca tctgatcaat
     7141 tcttctaacc gctctttttg gcccatcata tcaagataac ccataatggc ttcaaaacct
     7201 gtcgacatac gataggtaat aatatcggca ttcttagctt tagtatggct attggtattg
     7261 cgaccacgct tatagatgtc ttcttctttt tcggtcaata gctgcgcttc taacatagcc
     7321 tgaatcaagt tggcttgtgc cttagcagaa acatatctcg ttgctaaacg gtgtagctgg
     7381 ctaggtttcg ttttaccttg aaaaatgaga tgacgacgaa catagtagga ataaaccgca
     7441 tccccttcaa aggctagggc aatgccatta atcaaattca catcaactgg attagtcacg
     7501 cagccacctc acaccatctt tggtatctag cagcttgatg ccttgagctg ctaactgatc
     7561 tcgaatggca tcagctgtgg caaaatcacg attcgcgcgt gcttcttgtc gcttagcaat
     7621 caaggcttca atgtcaacct caagcacctc ttcttcaaag ataataccaa aaacagctaa
     7681 cattttctca aaagcgcttt taacaggttc tgtataggag ccagaattaa tccacttggc
     7741 catgtcaaat acgacggtaa tcccatttgc tgtattgaaa tcatcgtcca tagcgtcttg
     7801 gaaagctatt acaaactgtt ttagctcttg ctcatctgca gtttctgtca gcggttgttg
     7861 caaggtgttt ttaagatact tcagattgat ttccgcatca tgaagagcct tttcagtgaa
     7921 gttaattggt tttcggtact gttgtgtcgc aagaaagaat cgcaaaacct gaccatcaac
     7981 ggtttgtaac atgtcatgaa cggtcacaaa attacctagt gacttggaca ttttttcgtt
     8041 atcaacagtg acaaacccat tgtgcatcca atagttaaca aaagtcttgc ctgttttggc
     8101 ctcagattgg gcaatttcat tggtatgatg aggaaattcc aaatcagctc cgccaccatg
     8161 aatatcaatg gtatcaccaa gaatttcagt agccatcaca gaacattcaa tgtgccagcc
     8221 tggacgacca aacccccagg ggctatccca agaaacctca cctgccttag ctaatttcca
     8281 aagagcaaag tccagtggat tttcttttaa agctgtctca gcatctgttc gaccactggc
     8341 tccaacttca agttctgaca gggttttatt agctagcttg gcataatgct ctgacttttc
     8401 cacgcggaaa tacacatctc cagctgcttc gtaagcaaaa tctttttcaa tgaggctttc
     8461 aacaaatgaa atgatttctg ctatataatc cataacacga ggattttgtg tggctggctt
     8521 aacaccaagt gccttggtat cttctataaa agctgcaata aagcgatctg acaattcttt
     8581 aggagaaaca cctgcttgag tagcagcttt gataatttta tcatcgacat cggtaaaatt
     8641 ggaaatgtaa ttgacctggt agccagtata ctcaaaataa cgtcgaatgg tgtcaaaagc
     8701 gaccgctgat ctagcatttc caatatgaat ataattatag accgtcggtc cacaaacgta
     8761 catattgact gtattttcag tcaaaggtac aaacttgcgg agcgaacggg tcatggtatc
     8821 ataaatttta atcatgtaaa ctccttattc aatagcctgg cattagttgt catcttgata
     8881 tcctaagtct ttttctgaaa tgctgttcca ccttttcaac aatttgatat taataaccaa
     8941 acctattaac caaaataggg tcaaaatgaa gtatataatc gctttaacca tgtcttgtct
     9001 cagtaaaaaa attagactag ccaccagtgt aatactaaaa acaaggatag acaaactcat
     9061 aatgacatac agcccaactc ttattttatt catgaggctc ctttattaac gaaaaacctt
     9121 cacaacctgt gaaggcttca gaaagtagac aaacccactt ttatgctcaa aaagcatgaa
     9181 tagatctgct gatttgacat caggtttcct atttctgtat gtggggtgag ccaaaacagc
     9241 tgctttttgt tgtggtaaaa gtggcatcaa tactgacagt gatgcccata cggatgtttg
     9301 agaccttagg ctcaaaacta aggcatggaa ttccaaagga agtcgctgcc gtaagcacca
     9361 cctgagaaaa aatatcacaa tagactgttt cttcagtcta agacttgctt agttgatgct
     9421 cttttacgcg ttttttgtat tttgtacatt cccatatcac tacactcagc aaccaaactg
     9481 atagggctag ctaagttcaa cattactcta ctagaaagtc ccaaaatatt ttattggaag
     9541 gcatcagtgc ttctttttgt tattttccga tcattttgac aactgataag agacctctcg
     9601 ttgtttttgt aaactttgaa tttgacgatt atctttttgc ccatgcactc gtactatctt
     9661 agctggcaca cctacaactg tcacgtcttc aggaacatct gataacacaa cagctgctgc
     9721 ccctacttta gcatttgctc cgatgtcaat aggtccaatc acttgggcat gtgccgaaat
     9781 taaggcacct tgtcgaatcg ttggatgacg cttgccacaa tcttttccgg ttccacctag
     9841 ggtcacccca tgataaagca tcacaccttt ttcaacaatt gctgtctctc caataacaag
     9901 accagcacca tggtcaatga agactccagg agcgatttgt gctccaggat ggatttcaat
     9961 ttgtgtccaa aatcgccaaa attggctatg cattctggct agtaatttaa aatgatgtcg
    10021 ccaaagaaaa tgagacaaac gatgagcagc tagggctttg atacctggat aagttaggat
    10081 aacctcaaga ctattacgag cagctgggtc tagagcttta acaatagcta tactttcttt
    10141 ccaccaaccc atactaactc ctacgactta tctaattctg accaatcaac aagaatttgt
    10201 tggtcatcaa aaggattgat ggcgacaccg aacgtttcat caagctcgtt ttcaccattt
    10261 cttggttgat aaatatcatc aatcgtccaa gtcagaatca ctccttcagc tttcctgaaa
    10321 aggcctccaa aatcgtcttg gttgtaccat ttcgcaaagc tttgaagatt tgaaaaggcg
    10381 ggaacatagc tttttccttc aggcgttgac atggtaggaa aaaggcggtc gtaatggtta
    10441 ttatctttag gataaacaaa ggcaggaaca aggtaaacct tttccatcgt atctgccgcc
    10501 acattgtcat cactcataag cgtatttaac acagtggtgt aatggttcat aaattgaatc
    10561 atatcactgc ttttgaaaat ggtagaattc ccaaaatctc cctttttctt aaggttaaag
    10621 acaagacctg ctgcaccaga tgtaatgact tcttctagca ctgcaagagc tgaacgctcc
    10681 agccaatact gactttgagc actctcttgt tcttctttaa agcgagccat atcttcctta
    10741 tcggtaaaaa caggggtaac cttgacacct tcgacttcta tcacgtaggg ttctttagca
    10801 gcccagacag gaaaattatg gaaagcattg acaagggcaa cactatccaa aaagttatca
    10861 ggcgcattga taaaagctct taagcgaata tctaattcat ttgatttagt catgtttttc
    10921 ttcttttttc tctggttttg gtgggcgtgg aatcaaagct ttaattgagg catccacacg
    10981 acccttctca tcaatcttaa tgaccttaac atcaacgtct tcacccactt caaggacatc
    11041 tgacacgttg gtcgttctag tccaagcaat ttcagaaatg tgaacaagtg catctgtttt
    11101 gtcaaagagg ttgacaaagg caccaaattt ctcaatacgg acaaccttag catggtaaac
    11161 ttcgcctacc ttagcttcac gtactaggcc agcgatgatt tctttagtgc ggttaatggc
    11221 agcttggtca cttgagtaga tagagacatt tccttcgtca tcaatatcaa ttttgacacc
    11281 cgtttcggca ataatcttat caatggtttc gccaccttta ccgataacca ctttgatttt
    11341 gtctacgtca atcttgatgg tgtcaatttt cggtgcagtt ggggctaact caggacgtgg
    11401 ttcagcgata gttgcttcaa tcacatcaag gatttcaaag cgagcttttt tagcttgtgc
    11461 aagagcttct tctaggattt gaggcgtaat ccctgcaatc ttaatatcca tttgaagggc
    11521 tgtaatccct tcacgagttc ctgccacttt aaagtccata tctccaaagt ggtcttcaag
    11581 accctgaatg tcagtcaaga cagtataatt tgtcccatcg gaaatgagac ccatggcaat
    11641 ccctgccaca ggagccttga ttggtacacc accagccatc agagcaaggg taccagcaca
    11701 gatagaagcc tgagaagacg aaccgttaga ttctagaact tcggcaacta aacgaatggc
    11761 ataaggaaat tcttctaagc ttggcaagac ttgttcaaga gcgcgttcac ctaaggcacc
    11821 gtgtccaatt tcacgacgac cagcagctcc gtaacgaccc gtttcaccaa ctgaatattg
    11881 cgggaaattg tagtggtgta aaaagcgttt tttgtactct ggagccagac catcaatgat
    11941 ttgagtttct cccattggtg ccaaggtcaa aactgatagc gcctgagttt gaccacgtgt
    12001 aaagagacct gatccatgta cttttggcaa gaagtcaacc acagcatcaa gcggacgaat
    12061 ttcgtcaatc ttacgaccgt caggacgaat cttgtcctct gtaatgaggc ggcgcacttc
    12121 agcatgctcc atttgttcaa ggatttctgc cacgtcacgc ataatggttg ctaggttttc
    12181 gtcttctgcg taacgctctt cgtactcagc cttaaccatt tctttaacgg cttctgtggc
    12241 tgcttcacgc gcttttttct cttcaacttg aacagctttt tgcagttgag cattgtactt
    12301 agccacaata tcagcttgta agtctgcatc aacctgtaac agttcaacct cagctttctc
    12361 tttaccaaca actgctatga tttgttcttg gaaggcaatt aattcttgaa tggcttggtg
    12421 accttttaaa agagcctcaa gcatgatgtc ttctgataat tctttggcac cagactcaac
    12481 catattgatg gcttctttgc taccagcaac ggttaattct aagagtgatg cttccatctg
    12541 ttctttatct gggttaatga tgaactcgcc atcaatatag ccaacttgaa cacctgcaat
    12601 cggtccatta aatggaatat ctgagattga caaggccaga gatgagccaa acatcgctgc
    12661 cattggagcg ctagcatttt catcataaga aaggacagtg ttaatcactt gtacttcgtt
    12721 acgaaaacct tcggcaaaca tgggacgaat cgggcggtca atcaagcgag ctgtcaaggt
    12781 cgcatctgtt gaagggcgtc cctcacgctt catgaaacct cctgggaatt taccagcggc
    12841 atacattttt tcttcgtaat taacttgaag ggggaagaaa tcacccgttg ccattttctt
    12901 agacataaca gctgcggtca ggacggttga ttctccgtaa cgaacaacgg ttgccccgtt
    12961 ggcttgctta gcgacttgac caacttcaac aacaaggggt ttccctgcaa atgttgttgt
    13021 aaaggtttgt tttgacatat attctccttt taattttcag aggggtaaag aggtacctgt
    13081 tctctgctta gattcagttg ttatacgttg ttttgctaca aaaagcaacc tgtcaggctt
    13141 gtcacaagct cctctttgta tcaaacgacg tatctgctac attttaccat aaaatagcag
    13201 aaatttcact gtcagatcgc aatctcttga aatgtccttg aaaaatatta aacgaaactt
    13261 atactcttta acaaagcaaa aaaagcaggt tggtatacct gctttcgtct cctaatatta
    13321 atgtttggca tcctctaaaa ttttaaagcc gaggctggta ctgtctttca gaaacatttg
    13381 cacggtttca agggaatagt cttctaaatc ttttccttga agaggcaact tggcaatcaa
    13441 atcagtggta caagtgataa tgtccacgcc tagctgatca gcttgataga tattataagt
    13501 ttcacgagga ctagcccaca acaactcgac cccttctttt tgacgacaaa tgcgtagagc
    13561 ttcttccatg attggcattg ggtcaacgcc ggtatctgca atacgaccag caaaaacaga
    13621 cacaatagct ggcactccag cggttaaatg atcaaccaca gcttgagtct gctcaattgt
    13681 aaaaatggct gtgacgttta acttaatgcc tttggctgac aacttttgaa tgaggggaca
    13741 ggttgattct cctgttgaag tggtgactgg aattttcaca tagacattgt cacctagact
    13801 ggcaattttc tcagcttcct tttccatgct tgcgagatca tccgcaaaga cttcaaagga
    13861 cactgggtag tctgtaattt tggcaagcac ttctttggca aagccaatat aagaactgat
    13921 gcctgctttt ttcatcaaac ttggattggt tgtaaagcct gtgaccaaac ctgtttgtaa
    13981 atcctttaac atggtctcta aaaccgcacc gtctgaaaag actttaacgt ttagtttttt
    14041 tgtcatcata tcctcctttt agatttcttc tgaaacatta ttgatggcct cttgagattt
    14101 tgacagaaag tttggaagca ccaatacaat agcaagcaca gcaaccacca agtaaatacc
    14161 gatttgacca atcgacgttc ctaagcggcc cagtaaaatc cctaaaacac cgaaatccac
    14221 atctccaaag gtcgtgtttg aaaaaccaag tttaccaagt acaggtagaa gcatggctgg
    14281 caagaaggcg agtaataagc cattagcgaa agcaccaatc atcgcaccgc gacgaccacc
    14341 tgttgaattt ccaaaaatcc ctgctgttgc accgcagaag aaatgaggca ccatacctgg
    14401 gataatcaga acaccacctg caactcctaa aatcaacatc ccaagtaagc caccaacgaa
    14461 acttgacgca aaaccgatga taacagcggt tggcgcataa gggaagaata ccgcacaatc
    14521 cacggctgga atagcatttg gaattaattt gttagcaata ccttggaagg ctggaatcaa
    14581 gtcagccaaa atcatgcgaa caccggcgta gacaattgcc acaccaaccg caaaggtaag
    14641 accactctta atagcaaaaa taaatgggtt ttgacctgct gctaattctt ctgttactga
    14701 agcattcctc aaaacagaag ccactgttgc caccaagtag aaaatcacca tgataagtcc
    14761 tgttgaaatg gtggtgttgc gtaagaaact ccatttttca gaaatctgaa ggtcctcggt
    14821 atctttactg tctttgccaa ccttgctacc aacccaggca gaaaggtaat agcccaaact
    14881 accaaagtgt cccatggcga tttcatctcc gtcagtcact ttcaacgtat actgttgacc
    14941 aatggctggc gaaatagctg accaagctcc caagaggaac ccacctaaga taatcaaaag
    15001 acttcctttg aaaccaacag ctccaagcac ggcggacaag agacaagcca taaagaagct
    15061 gtgatgtcct gttaagaaaa tgtatttgaa gcgggtaaaa cgagcaaaag tcaaattgag
    15121 caataaccca accaccaaga tggacatggt ttccacaccc agaatctttt gagcgacaga
    15181 agtgacggct tcattatttg gcactacgcc agtgatgcta aaaccgtgct caatgagttt
    15241 ggcaagaggg tctagattgg tcacaataac acccgcccct gcagcaagca taaggtatcc
    15301 caaaatcggc cccaaggttc ctgtcaacac cttatgagca ggtgttttca aagccaccaa
    15361 ccctgcaaag gcaatcaagc ccattaaaaa tgcaggttct tttaaaatat ctcgaataaa
    15421 tgataataat gcttccatgg tatcttccta tctcctttaa aggcttattc cttgccactc
    15481 atttccttga gaaccggaac caaatcttct tcaatttttt tacgattggt atagctttta
    15541 acgatacaaa ccttggcatc ctctggaaaa atatctttaa attctttaac ggtaacaaac
    15601 aaatctgcat cctttccaac agccgcattg gaatcacagg attctgcatc cacatcaata
    15661 cccaaactag atgcgatagc ttctactttc atgcgaagta acaagctact accaataccg
    15721 tttccacaaa ccgttacaat tttaatcatg tgattcatct cctttttcaa tcatatggct
    15781 aatcagactc attatttcct cagtattctt agcctcaatt aattgctcaa tatgttcatc
    15841 atcatctaaa atcaacgaca gttcctgcaa agccttcaaa tgtgaactag aatccacagc
    15901 agacaaaaca aaaatcaatt gcacttgctt gtctggatca ccttcttgct tcaaatcaaa
    15961 gctgacaggt tcttttagtt gtaagagaga catgcctaac tgccgtgctc ctttttcagg
    16021 cgccgcatga ggaacagcca ccttaggggc taaaacaata taggccccaa gctcattgac
    16081 cgaatcaatc atgccgtcga tataagatgt ttcaatcatc tggtgttcta gtaaaggctg
    16141 agcagccaaa cgaatcgctt cctgccattc cgaaacagca tcagcctgcc taataaaatc
    16201 tgctgttaac aagtccaata gtcctagacc tcctttttca atcgttaaat ggttaccaat
    16261 caggtaacgg gataaatcac taacaagtcc ttctttatta gtaatcgtgg tatgtttatg
    16321 aataatactc aacaggtcat ccaaagcgaa ttgctctgac aagggaagat gaaagtcatc
    16381 acagaccatc tttttcaaca tcattttctc aacaggcccc atcaaagctt gcgtcacata
    16441 aacaggttta gcacagtcaa aagctactgt tgaaaaaatc aaatcaaagg aagctggatc
    16501 caacaacttt attttgtcca gctggtgaat cctaataaac tgtagctgtg gaaaaagttc
    16561 cttcaaggtt gcctccaaca tcagagacga actaatgcca ttagggcaaa cagataaggc
    16621 taccagctga ttgcttggcc tcttcttagg ggcctgcaac catctcccaa aatgaatggt
    16681 aaaataagcg acctcatctt cattaactag tttccccaat tgtttttcta gaggagaaag
    16741 gctgcgcttg accaagtaaa agagagattc ataatcttgt ttgatttgtt tcttcaaagg
    16801 attggtcaag ttaatgtcgt agtaaagtcg gtaataagct ggcaaaaggt gactgtatag
    16861 gttctgacga agttctgggg tatcggtgat agacaatccc gtgttaaccg ccaccgaatt
    16921 gatgatttcc tccataatgt cataaatagg ttgctgaaag actaactcta agtcaccttg
    16981 gatacaacca agtaacctag attgaaccaa atatttttct tcggttagac tggggaagtt
    17041 gaccaataac tggtccacca tcgtttcaac agctggcgaa gctaaaggaa aagtatccac
    17101 tgcttcagct cttacattcc gtgaaaatgg tcgatgagcg agaaggcaga aaaaataaat
    17161 caaatccctc aatttctccg aaataaaagt taagtggttc tccctgctca gttcctccaa
    17221 cgttgctgcc atcacctttg tctggtcggg caaaccaagt tcatgcaata agtaactgaa
    17281 cacccaagat cctgatatga cttgcaaaag agaactgacc gctgattcta agagacgccg
    17341 caaggctaag ggttctcctt caaaaaaata accatcctgg cgattgtaag ctaaagttac
    17401 ctgaaaggct tgtacccgat cacgcaccaa gtttaaatca gcaataacag aatttctgct
    17461 taggcgtaac aagctttcca agtggttaat ggagataaat tctttagcca tcatgatgta
    17521 aatgataatc atgtccagac gctcatcttg aaagagatag tcgtctaagg taggtagcat
    17581 gcgattcaac aagtcctttt cagtaaggtc tggcggataa accagctgcc tgtccagagc
    17641 aataaggggt aactgataga gtgacaacgt gtcattgatt ttagcaatat ctgccagtat
    17701 atgacgtttg cttgtcttta atatggattc aaatgcctcc agtgaatgtc ctttatattt
    17761 agaaaagagt tgatagtttc tgatgagctc gtgagatagc atgtcatctc ctcctataat
    17821 gtcagtataa aatgaagcgt tttcattttc aagacaaatt gagtccaatt gtctctcgtc
    17881 atttttaact gcaattggac tcaacaggtg atatcattgt aacaagttcc tcaaaaggtg
    17941 gcaaaaaata ggcaaatctg ggaattgatt ccctttttct tcatgataca acaaaagata
    18001 cctcatcact gagatacctt ttgttgctaa ataaaatcat caactgctaa aaaaacagtc
    18061 ttagaccatt ctagccaaat gtgtaagtta acaaacaaca tgtcaaaaat gaaaaagccc
    18121 actgcataag cagaggactt tttaaacttg aaattaacga cgaagtccaa gagattggat
    18181 caactcacgg taacggttaa catctgtacg acgtaggtat gccaacaagt tacgacggtg
    18241 accaattttt ttcatcaatc cacggtaagt agcgtggtct tttttgtgtt ctttgatgtg
    18301 gctgttcaag tggttgattt cccatgtaag aactgctact tgaacttcaa ctgaacctgt
    18361 atcgccttcg tgacgtgcat attgagcaat gatttcattt tttttctctt ttgagattgc
    18421 cataatatat tctccttttt ttgcttaatc cgagtcctag gattggcact cctaaaacca
    18481 agaaaaagtt ggtttgtctt tcgaccactc tattctagca gattcataat attaggtcaa
    18541 ccgttatcct attattctga gctctcacat ccaaaccacc tcactaggct taaaaaggtt
    18601 atctggtcat tgaatgtgct ctttttgctt taaccaaacc accataagca acagaactag
    18661 caaggccaaa tagccaaaag gctgttttta aatcagaata aacctgtgcg attgcttgcc
    18721 taataagata accagctaaa agaggtaaga tggctgatcc cagcacttca gctgataagc
    18781 ggtagcctag catagtcatt catttctttc caataaagtg ttcactgata atatgaattg
    18841 ctctagtatt aacaaaccca atccctaatc catgaacaca gcttattaac cgatgctacc
    18901 tgcctttatg acataggtca agagttgaca caaaatgttt gccaacaaaa cattacctat
    18961 accgtcaaag agcgctttgc ttcctatatc cttaaagcgc aagccaacca agaggttcat
    19021 ctgaacttta cattattagc aaaccgtttt ggaataagtg atcgccatct taagcacgta
    19081 cttaagcagc tcatttttca gaggattatc gaacgcatct gcttcaaaac ctgtcgtatt
    19141 gccgatttag acgctctaac tcaattaagt gttaataact agacctctga ggtatgcagc
    19201 ccattaactt ataatagcaa tcactctgac cactacctga cttttcttta aaaaagaaat
    19261 gatttgtgat atagtaaatc cagttaaaaa aaagtaaagg agtagacatg tctgcacaag
    19321 ataaattaat taaacctagt catctgatta ccatggatga cattattcgt gaagggaatc
    19381 caactttaag agctgtcgcc aaagaagtga gcttaccctt gtgtgatgag gatatcctat
    19441 taggagaaaa gatgatgcaa tttttgaagc attctcaaga tcctgtaatg gcggaaaaac
    19501 ttggtcttag ggccggtgtt ggtctagcag ctcctcagat tgatgtgtca aaacgtatca
    19561 tcgctgtgct cgttcctaat cttcctgata aagaaggaaa tcctcctaaa gaagcctata
    19621 gctggcaaga agtcctgtat aatcctaaaa tcgtttctca ttctgttcaa gatgcagccc
    19681 tttctgatgg tgaaggttgt ttatctgtcg atcgtgttgt tgaagggtat gtggttcgcc
    19741 atgctcgtgt tacagtagac tactatgata aagaaggaca acagcatcgc atcaaattaa
    19801 agggatacaa cgctattgtg gttcaacatg aaattgacca tatcaatggt gttttgttct
    19861 acgatcggat caatgctaaa aacccctttg aaaccaaaga agagctcttg attttagact
    19921 aacaaaaaag gccctttagc ctttttttgt tagtctaaat agccgctaaa agagcctctg
    19981 cctgagatag caagtttgct tttgtctctt ttgaaatctc aagccttcct gttccccagg
    20041 catcaggatt cacagttgct tttgtaaact ctcctgctac tgaagttcgg ataaacggca
    20101 atagtgcttt aaactgatca aatacttgat catgcccgcc atttgcaact gaagagaccg
    20161 taaccacctt accgccaata gcagatgggc ccgtcggatc agacaaatca agagcacgag
    20221 acaaccagtc tagcaggttt ttaacagaac ctggaataga gaagttgtaa actggtgtaa
    20281 aaatccagat agcatccgct gactgaacag cttgacgagc gtcaacaact ggtaaaggtg
    20341 cattagcttc gatatcttga ttcaaaacag gaacgtcttt ccaatttaag taagatacaa
    20401 ctgcttgatg ttccagagct ttttgtgctt gagccgctaa ttgatggtta aaagaccctt
    20461 cacgaagcga gccaacaata aataaaatat gtttcatctc tttgtcctct ttttttaaag
    20521 atcgttttaa agctttctaa aagtggtatt tcattgatac ttctttttga aatttatcac
    20581 tatgtagtaa ttatatcttc tctaagaaga gctgtaaaga gatttgttta taattgtttg
    20641 aactttttga gaagttcaat cagacaaagt tgttcttttt cagtcaaaac agcaaaggct
    20701 tcttccaccc gtgcgacgtg tttaggcaaa acagcttcaa tcaagcgagt acccttatct
    20761 gttaaggtaa ccacataggc tcttttatcc gttttgtctt tgcacttgct aatccagcca
    20821 ttacgttcca tattatttag tacaacagtc atattccccg aagtcgctaa caaagaatca
    20881 atcaagtgat tgattcgcat acagccttta gtatatagta cttcaagcac actgaactgc
    20941 gtggctgtta aatctgcctt tttaaaaata tcagccccaa aagcatctag cgttcgctga
    21001 gctttacgaa acaccaccat ggctttcaaa gcggtgttct tatctaaatg actcatttga
    21061 tttcctcgct ttatacggta tgtcacaatt tagtatcaga gagattagaa agtgatcttg
    21121 tccctcttct tttatgactt tgcatatgac taccattatg ataatctaga aaaagtcatc
    21181 aaaaagactt aattgattat cttctggcat atttcctaaa atacctatct catccatttt
    21241 ctcaacgagc gttgacgatg ccccgcctcg tttacgcaat tccattttag agaggaattc
    21301 gccttcttga cgagctttaa cgatttgctt ggccacgttt tcacccagac cttctaacgc
    21361 tataaatgga gggataaggg tatctccttt gatttggaat tctatagcat cacttttgta
    21421 aaggtctaat ttgccaaact taaagccgcg ttctaacatt tcgttgacaa tctccaaggt
    21481 tgtaaagagg tcattttcca cattggtggc ttcattattt ttacgtttta tagtaatatc
    21541 ttccattctt gctttaacag catctaagcc accactcatg gtttttaatt caaaagcctt
    21601 cgcacgaata gagaaataag cacaataata cataatgggg tggtgcacct tgaaataagc
    21661 cacccgaagg gccatcaaga cataggccgc cgcatgggct ttagggaaca tgtacttgat
    21721 ttttccacac gattcaatgt accagtcggg cacattgttt tctcgcatgg catcaatata
    21781 gccattacgt tcttcctcag aaattttcag ccagaggccc ttacgcacac gctccataat
    21841 ggtaaaggcc attttcggtt ctaagcctgc gtgcatgagg taaaccatga tgtcgtcacg
    21901 acaaccgata acggttttta gggtcgcaat gccttcttta atcaaatctt gtgcattacc
    21961 aagccaaaca tcggttccgt gagatagccc agacaactgc aacaattctg caaaagtggt
    22021 cggatgcgtt tcgttaacca tgccgcgaac aaagttggtc ccaaattctg gaatgcctaa
    22081 cataccagtc ggtgtcccaa tttgttccgg ggtaacgccc aaaatctctg tcccagaaaa
    22141 gagagccata acacctggat catcagcagg gatagtaata ggatcaatgc ccgataaatc
    22201 ctgaagttta cgaatcatgg tcggatcatc atgccctagg atatcaagtt tcaagacgtt
    22261 ttcatcaata tcatggaagt taaagtgagt tgtctgccaa gaagccgtta catcatcggc
    22321 tggatattgc acgggggtaa aatcataaac atccatgtaa ttaggaacaa caacaatccc
    22381 cccagggtgc tgcccagtcg ttcgtttcac accagcagca cctgctgcta gacgatccac
    22441 ctcagcatcc cgatagaact tgccatagtc gcgttcatag cctttgacaa atccataagc
    22501 tgttttttct gctacggtac caactgttcc agcacgaaag gcgtattcgt caccaaaaat
    22561 atctcggaca tccaaatggg cactcggctg atcatcacca gagaagttca aatcaatatc
    22621 gggcacctta tccccgtcaa atccaagaaa ggtctcaaag ggaatatctt ggccgtcttt
    22681 ttgataaggg gtgccacatt ttggacaagg cttattaggt aaatcatagc ccgatccgac
    22741 tgacccatct gtgataaatt cagaatgttg gcaggacggg caaacgtagt gaggcggcat
    22801 aggattaacc tcagtaatcc caatcatggt tgccacaaaa ctagacccta cagatcccct
    22861 agagccaacc agatagcctc gctcatttga ccggttaaca agcatttggg aagcgagata
    22921 aatcacagca aaaccgttcc ccaagataga ggttagctct ttttcaatgc gtaaatcaat
    22981 aatatctggg agaggattac cataaatttc aaaggctttt tgataggtta attcggcaac
    23041 cgtctcttcg gccttgtcaa tatacggggt gtaaagatcg cccttaacca cttccacttc
    23101 ctcaatacgg tccgcaaaat cctgagtatt ttgcacaacc acttgataag cgaggtcttt
    23161 tccaagaaag gcaaactcat ccagcatttc attggttgtt ctaaagtgcg ctttaggtag
    23221 aggagcaggt tgggcccctt ccccacggcc gattgttcta ttaatcatgg caccctgacc
    23281 gagactacgc acaataattt cacggtaaat ttcttcttca ggctccagat aatgcacatt
    23341 tccagtggca agcacaggtt tcttagctcg tttccctact tcaatgaggt cacgaatcac
    23401 ctgctcaata cctgcttggt ctttgattaa ttcacggaca accaatggct ggtaaatggc
    23461 tggtggcatg atttcgataa aatcataata cctagctaaa tcaaccgccg catcaattcc
    23521 tttagtcaga acggcatcaa aaacctcgcc gtcagaacaa gctgtaccta gtaacaaacc
    23581 ctctcggtga gcatctaaga cggttcttgg aatacgcggc accccttcaa aatatttgat
    23641 attggaaagg ctgaccaact taaacatatt tttaagacca acctgatttt gcacatagat
    23701 agtcgcatgc ttaatccgcg cttttttgta agaatcctca gccaccaaat ctgtattgag
    23761 ttgcaaaaga tttttgatgc catgcttttc tctggcatct cttagaaaaa taaacaaaag
    23821 acgtcctgtg gcttccgcgt cgtaattggc catatgatgg tggtctagac tcacttggaa
    23881 acgcttggtg agcggtccca aaccgtgacg cttgtactca ggatacaagt ttctagcaaa
    23941 ttctaaggta tcaatcacag gctgtgtgat tttgggcaag tcgtggcgtt cataattggc
    24001 gttcataaag cccacgtcaa aactggcgtt gtgagcaacc aagatactat ctttgcaaaa
    24061 gtcctgaaaa gcttttagga cggtaaccaa tggcttggcg ccctgcaaat gcttatcggt
    24121 aatccctgtc aattcggtgg taaaggcaga aagaggatgc ccaggatcaa tgaattcatc
    24181 aaactgctct acaatatttc ctttaaacat tttggaagcc gcaatctgaa tcaggtcatt
    24241 attcatagca gatagacctg tggtttccac gtcaaagacc acataggtag cttcgtgcaa
    24301 atccatatca acaggatcat aagaaatagg caccttgtcc tcaacaatat tggcttctag
    24361 gccaaaaata gccttaattc cagctttgcg agccctatgg tagccatgag gaaaactttg
    24421 cacattagca tggtcggtga tagcaaccgc cttgtgtccc cacttggctg ccgtatcaat
    24481 caagctttct actgtcggta aggcatccat ggtagacata ttggtgtggg catgaagttc
    24541 gacccgcttt tgcccttctg gcatcaggtc tttgcggtca tgatggacaa tttctttgac
    24601 ctgctggaca ttcatggtga gactcttcgt aaaaggattg gtctcaatat tcccttgtac
    24661 ccgtaaccaa gcccccttag caatcatatc aaatttacgg agctcctcat cgtctttggc
    24721 ccatttttgg agagcaaacg aggaggtata gtctgtcatt ttaaagttaa tgatatggcg
    24781 acctgttcta gtcgttttac gctccacgtc aaaaaccatc ccctcaaaga caatccggtt
    24841 ttcttcggtc tcaatctcta tcattggtgt gatggctgct ttttcaaacc ctgcctgacg
    24901 cttagctgct cgttccttgt agtcaaactt aggagcaggt gtggcttcct caactggtgg
    24961 catcatggct tcaagggatt tttgggcttc caaattatcc tgcacagcct ttttcacaag
    25021 agcctgacga ctggaaacaa aatccttggt caaatgctca gtcatctcct gatctgacac
    25081 catatctatg gtcaaggtgc caaagccaaa ggcttctaat tgcttgacca gattaggcaa
    25141 atgatttttt ctaaaatgat cgttattcac aaaacctggc gctgcaataa tgagtttgtc
    25201 atcctcataa gtcactttga gctttgagaa agaagattta aaactagcac tattacacgg
    25261 tgcatgctca aaagcttctt ggtaataagc ttgaagcaga tcatctgaat aatccacctg
    25321 agcagcttgg atatcaaagg ttaccttaat gtcagccgcc tcaaaagttc gcgtcaaacg
    25381 atcatgtaat tcacgataag ttgcaatcgg taaaaccgcc gcaaaggcaa aatgaaattc
    25441 ccacaagcgt gacaccgaat gcacctttac ctcgataata tcagcagatg aaaaggcact
    25501 tgaacgtctc atgtcaagtg gcatttctat ctggtccatc aatttagcga ataaatctga
    25561 cataattttc tcctgatttt actaggcttt attttatcac aattcaagat gattttcgag
    25621 ttttagatgg aaagaaaagc agggctttct tctgacgttc tttggctaat ttattccaag
    25681 tgatagctca gttgaggtca tttttttgtc aatcttttat cgccaagcgt ttttggtaaa
    25741 gcaaaagcca ctctgtacca gacaagttca cagcaaaaag aggccactct aaacaggcag
    25801 cctcctcatt tcttttttag tgttcttttg ttaaaatttc aagggtttcg atgaggtttt
    25861 ctgcattaac ttcaatgctg tcacctgttg ccttgatttt aatttccacg ataccttcag
    25921 cggctttttt accaacagtg acacgaattg gcaaaccaat caaatcgcta tcagagaatt
    25981 tcgaaccgac gcgttcatta cggtcatctg tcaagacatc atacccttta gccatcaagt
    26041 cagcttctaa cttcgccgtc aagtcttggg ccacttgatc tttgacatta actgtaatca
    26101 aatgcacgtc aaatggggct aattctttag ggaagttaat accccaagca taacggtaat
    26161 cgccttttgg tgtcttgttc acaaagagac gggcatgctg ttcaatgaca gcagacaaaa
    26221 tgcggctaac cccgatacca taacaaccca tcacaattgg aactgttctg ccattttcat
    26281 caagaatcgt tgctcccatg ctgtctgaat aacgagtgcc caacttgaag atatgaccga
    26341 cttcgatacc acgcgcaaac tggagaacac catgaccatc cggagacatt tccccttctt
    26401 tgacttcacg aatatctaca tattcagcct ggaagtcacg tcctggattg actcctgtca
    26461 catggaaacc atccttgtta gctcctgcaa cggcattggt aaggttttgc actttgcggt
    26521 cagccacaat gcgactacct tgtgccaagt tgacaggccc aagtgagcca aaacctgcac
    26581 caaagaaagc acgggcttct tcttcactag ctggctctaa aaaatcagca gctagatagt
    26641 tttttaattt aacggtattg atatggtcat ttccaactag caaagcaaca acaggttcat
    26701 tatctgccac aaaaagcaag gttttgatgg tttgtgtttc atctactgaa agaaaagcag
    26761 ccacttcatc aatcgttttg caatgtggtg tctcaacttc tgccaaggca tcttcagcag
    26821 ctacttttga ggacggttta tattcgttag ttgccatctc aaggttggca gcgtagcttg
    26881 attttgttga ataagcaata gtatcttcac ctgaaatcat ccaagcagcc aattctgcct
    26941 taatctcttc taagacctct tttggaatat catccattga cgcaatagac ttgtcaagaa
    27001 ccacccagcg atcaaggtcc gtacgagctg gtgtaatggc cataaattct tgggaatctt
    27061 tcccccccat ggcaccgcca tctccaataa tccctttgaa atctagacca gctctggtaa
    27121 aaatagcttc gtaagcttga cgataatctt cgtaggtcac atctaaatct tcatagttgt
    27181 gatggaaact atagccgtct ttcatgataa attcacgggt acgaagcaag ccattacgcg
    27241 gacgtttttc atcacgatac ttagactgaa tttgataaag gtttaagggc aattgcttgt
    27301 aagatttgac cgcattacgc accaaagtcg taaaggtttc ttcgtgagtt ggacccaaga
    27361 taaagtctga gttatcacgg tttttaagct tatagaggtc ctctccatag gtctcataac
    27421 ggcctgattc acgccagaga tcagctgtca aaagagctgg tgccaacatt tcaacagcac
    27481 cgatcttttc aaactcttca cgcatgatgg tcttgaattt ctcaatggta cgatttgcca
    27541 gtggtaaata agcatagata ccagcagaaa cttggcgcac ataaccggca cgcaccataa
    27601 gcgcgtggct gataacctgg gcatcacttg gcatttcgcg caaggttggg ataagcagtt
    27661 tactttgttt catagattat tccgttttaa tacatcccct tatcctcaaa cccttctgga
    27721 aacatcaagt aagagtgaag cgggattatt caataatttg aatgtgtatt cctttcattt
    27781 tgagtaagac ctcaaccctt gcaaatctta gggttgaggt ctttttcgat ctttaacatg
    27841 ataaggtcag cttaagatga cctatcttga ttagaaaaag acgcgcatga tatcattcca
    27901 tgtcacagca atcatcaata cgaccatgat agcaacccca gctagggtga tataggcctc
    27961 tgtttcttgc ttgataggct tgcgacgaat ggcttcaatg atattcatca agatttttcc
    28021 cccatcaagt gcaggaatcg gaatcaggtt aaagatccct aaattgatcg aaagcattgc
    28081 cataagagat aagactgact ctaagccgtt ttgagcagcc tgattggaca tgtcatacat
    28141 ggcaacaggt ccacctaatt tattgagact aaagccagtg atcaatcctt tcaaagcatt
    28201 caaaatagta aacgccccac tccaagctaa ttctagaccg cctaagagct tatccttaaa
    28261 tcctgttttc agactcgcct taactcctat cgtgtatgtc tttgtatgct tttgtggttt
    28321 cacagccacc gtttttaagc gctgatgtga cttgtaggtg accttaatgg tctgtgacgg
    28381 gcctagatcc cgtgttgcaa ggtctacagc ctcagtgaga tcattccagc tagtcacctt
    28441 ataaccatta attgcgacaa tttggtcatt atctcgaaga ccagccttag ctgctgctcc
    28501 attttcttga acacggacat gattgctact aaaatctggc atcccacctt gtaaaaagac
    28561 caagaggata aaaaccacaa tccctaaaat aaaattattc atgggacctg caaaattggt
    28621 gattaaacgt ccgccaatac tagcattttg atattgaaca tcaagcggag caattcttat
    28681 ctcagtaccg tcttcttcaa caatagtagc atcgtgagcg accttatatg tcttggtttc
    28741 ttctaaaacc aagccagtaa tactcagctg atcttctaag tcatagcctg taacatgcat
    28801 tgggagactc gttgggtcta acttactttg agacaagttg atgcgcttaa caaaaccttg
    28861 ctcattaagg gttaaacttg ctggagtacc tgttttgatc tcagttttgt catcacccca
    28921 accagccatt cgtacataac cgcccaaggg taacatcctc aaggtataaa gagttcctcc
    28981 ttggtcaaca tgagaaaaaa ttttagggcc cattccaatg gcaaattctc ttactagaat
    29041 gcctgatttt ttagcaaaat agaaatgtcc aaattcatgg acaatcacta aaataccaaa
    29101 aataataata aaggttatta ttcctaacat agatttcctt tcagtctatt gcttttttga
    29161 gttttgtcgc gttgttgcga ctccaaacat tacctcttaa gattaaaata aaccaaagag
    29221 atgcatgatg ggaaaaacaa aaatcatgga atcaaagcgg tctaaaatac caccatgtcc
    29281 cgggataagc ttacctgaat ctttgacacc aaagtgacgt ttgagagcac tttcaaccaa
    29341 atcaccaaat tgggcaaaaa tggaaaaaag agcgaccaaa accaacatgg tcaaaaagtg
    29401 atgtggcgca taaacagacc tatcaatcac cataaagata aaagacacaa ggactgcaca
    29461 agcgatccct cctaaactac cttcaatggt tttgtttgga gaaactgtag gcaatagttt
    29521 gcgtctgcca aactgacgcc caatcagata tgctccaata tcagtggccc aaacgataaa
    29581 taaggccaaa aagaccttgt caattcctga caggcgagca ttgatcaaat gttgaaaacc
    29641 aatcccaaca taaaaactag ttgcaatcgg aaaggccgca tcatcaaatg aataagctct
    29701 gctatttaaa acagtacctg ccaaaatgaa aaaaaccatt aagctgtaaa aagcaacatt
    29761 cgcatcaatt ggtaaaaaag tgaggtaatg gtccatcgga actgccaata caaaggcggc
    29821 taacatggca aaaacacctt caaaagaaaa gacttctaat cttttcattt tcagtaattc
    29881 tgatacccca atcatggcca aaacgcctac aaataattgg aatggtaggt ttcctattat
    29941 gagaaaaggt aggaaaatag ctactgctac tcccccccaa acaacacgtt ctttcataac
    30001 tatctccttt tagaccttgc caaaacgacg ttggcggcgg ttataatccg caatggcctt
    30061 tagtagctct gcctttttaa aatcaggcca caagactggt gtgaaataaa attcactgta
    30121 agctgattgc caaggcaaga aattgctcaa acgcagctca ccactggtgc gaataatcaa
    30181 atcggggtct cggtagagat atggcagatg gtctgtcatc aagtaattag caatcaaatc
    30241 ctccgtaata tctcctggat ttaatttggc atctaagaca tcttgagcaa taaagcgaac
    30301 agcactggta atctcagcac gtcctccata attgagagca aaattcaaaa ttaaacccgt
    30361 attacgtttt gttttgtcga tggctgcatt tagcgctgcc aaggtatctt caggtaaacg
    30421 actagtctct ccaatcattt gaatctttac attgttctca tgaagcacag gcacatattt
    30481 gtcaaagaag gttactggta aattcatgat aaaagacacc tcatcttggg gtctggacca
    30541 gttttctgtc gaaaaggcat agactgtcag aactttaacc cccaactcag atgcagtaat
    30601 cgttacttct tgtaaagcat ccatcccagc tttatgccca aacactctag gttttagtct
    30661 ttttttggcc caacgtccat taccatccat gataattcca atatgctttg ggatactccc
    30721 caaaactttt tttgttgatt tcgcttttaa tccaaacatg ttttttcctt attgataagc
    30781 atacttatct catattttat catatttcac gccttttggc ttgtttttta tcaattagat
    30841 cttatcttca caaaatgttc acctatcctc tgatagatgt gtcagctttt catgaacctg
    30901 ttagcatcag aataacttca gtccagggat caaaacaaaa aagtttggca tatttcatcc
    30961 aaactttccc cgccttaatg gctttcaatg gcactgtcag tgtcagtgct atctactgtc
    31021 tcaacagcag gctcattaac aacactggtt tcttctgttt caaccagtgt cgtttctgtg
    31081 gtagcttttg ttacaatacg cttaatagct gatagctcaa atgtcaaaaa gacgccatcc
    31141 acatctaaca caatcttttt agctgttgta tcgacttcgt caacaatcgc aaacatgcca
    31201 ccaatcgtta cgacttcgtc tcctttttca atagcgttta actgattttg gcgttcttgc
    31261 gcttgttttt tttgttgacg ttgcataaac caaatcaatc caagcatcac tacaaacatt
    31321 aaaattgttg gaaatcccat aatgtctcct ttttattcta taaaagtcat gtcttactat
    31381 atcaaaaatc aagcggtata gcaagactag acgttacctg atttcttctt taaacgagac
    31441 gctaagcgca gtgctttact cacgagtcaa aaaagctaag atgtcatctg gtgtcaaact
    31501 tgaatcacat acagcccttt ggtgctgatc gtaactaacc agcaaagctg gaactgtcac
    31561 taattggtag ttctcacgaa aggcagcaag ctcagcagca tcagcagcgt tttcgctatc
    31621 cacaaaatag acgtcttttt gattatctgt tgccacttgt gccaacttag gagcaaagcg
    31681 gcgacaataa ggacagctcg aacgtcctaa aaagacaatc atgtctttgc cactagcaat
    31741 agctgatgtg acttctgcaa cactcgacgg tataaaattc gcaacgattt cttcaaatgt
    31801 catggatgtc tccttctctt ttggtctcat gatacactaa agcagcaatt ttctcaatca
    31861 caaggtcttt tcacagctca gagcttttat agccgtcaaa aagaatccgc aaacggcaat
    31921 ctttttgtct ctattaacac caccctaatc tttttggcgc ttcatcaaca ggctaatagc
    31981 caataaaagc agagctactc cagctgctaa taagcctttt gaggaggctt cacccgtttt
    32041 tgggagcttt tggtttgttt tagctctttt tggcctagtc attaatgatt tgtctaggtc
    32101 ttttgagcta tctggtgttt tggtttgatg attgtctgtc tgactctttt gctgagaggg
    32161 attagccgtt tttgaggata ctttgaggac cagggcagtt aggccatcaa tagtcaagcc
    32221 ttctttggta aactggactc ccttaggctt agcaatggca gtaacaccag cttgctcagc
    32281 atcagcaagc acttgggctc ctagcaaata gcggtaggct tgaggtaaaa ctaccttgcg
    32341 ggtcttgttg tctgcattga caaagacagc atagcgatct ccatttgatg ccaccgtttg
    32401 gtaacccatg atgaggtcct cttgttgaat accatcttgc cctgcttggg tgatcaaggt
    32461 cacatcccga tctacctcag ctttggttgc ttttgtaaag gcatctgttg agcgacgcaa
    32521 cgcaattagt ccttgtgtat aggcttttgt ttggttgcta atcgggtgag ctctggaatc
    32581 tgttgccttt gcccagtcaa aatgattgac cgcatcagac gaatcataag aatcgtggat
    32641 gaagtaaggg tattgcgcta cagcatcaat cagagtcgcc ttatttggca ccttgtcatc
    32701 agacaccttt gtcttgtagt cgggatttag aagctgcttg gttcgtccat attcctgacc
    32761 agaatggata aaggcagtcc cttgagcagt taaaatcatg gtatttccta gacgaatacg
    32821 cttgtgaatc tcttcttcag ccactttagg atccttattg atggatttgg caatgacatc
    32881 atgtaaggtc aggttgtcat gggctgcaat atactgcact acatctccag gggcatctgc
    32941 ttcaaaatta ctaggctgtg ctttgatcgt tttgaataaa ccttctagat tttttgcgcc
    33001 accagtaata aaggctgctg tgccttcatt tggaaaacct gatttgaggg tatttctgat
    33061 atcatcagag aaaacaccga ccgtattggt tgctttcatc caatcttgat ctgccgcaat
    33121 ttcttttttc ccctcatcac cttggtaggt acgccagcct tcgccaatca taatggtatt
    33181 tggattaatg gctttggctg ccttaaaggc ttgctcaata gctgccgcat catggtcacc
    33241 catcatgtcg aaacgaaaac catctacctt gaattcacga gtcagataag taatcgaatc
    33301 caccaagata cgacgactca tggcatgtgt cgttcctaga cgacctccgc caaaactctc
    33361 tctagctgta ccatcagcat tcataaaatg atagtagttg ggttccaaat cttcaaagag
    33421 ataggttcta gccgtgtggt tataaaccac atcaaaaata acacccatac cacgtttgtg
    33481 aatctcattg acaaggtttt taagctctgc gatacgtaaa gcagggtcgt taggatttgc
    33541 cgaatacatg ccagaaaggg caaagtagtg ttgtgggtca taaccccagt tgtaattatt
    33601 gtctgaagac gtgtaggctg ttgagcggct cttgtccagc tcattggcat aaaaataact
    33661 caaaaccggt agcaattgaa cgtgggtaac ccccaagtct ttgagatagt ctagctgttc
    33721 aacgaaagct gaaaaagtcc caaaagggtg tgttaacttg ccttctagag ccttatctga
    33781 cgtaaaatct cgcacatgtg cttcatagat aatagcgtct tcacgctttt taaagttgtt
    33841 aattttggca aaaccaaggc ctgttggtcc tagtttgctt ggatcaataa aggcagcttt
    33901 tgctgttttg atgtcatcag tagcagtcgc atcattccag gcagcgagag atttggcgta
    33961 aggatccaaa accatgactt tttcctgacc gcgcgtgatt tcataaaggt aatagtagcc
    34021 tgtgtaatca ctaatgccct tgacactatc agaagtcaga tgagctctcc aaacaccctt
    34081 gtccgacttg gtcaaatcag cttgaccaac cacccttgtc tgatcttgtt tatcataaac
    34141 gacaacctta acagtatcag cacttggaga ccatagcgct aaatcaacag aaccatcctt
    34201 agctagggta gctccaagtt caccatcgta agcatagagt ttatctttta attgccagga
    34261 ttggcgagcg acttggctaa cttctccaaa tgtaaccgtg tagactgcac cttgcgcctt
    34321 aaaatcaccc tttaatgtca ttacagactt atccttgtca agtgtcaact catcaattgc
    34381 aacagttttc cctgctttgt cagtgatctt gatgttttgt ttcaccgcat cttcatcaag
    34441 cccatctaag gtcgtaaaaa tggctttaat ctcatttggc gtggtttgtt cagctccttt
    34501 gagactaacc tgatcaatat aataaggatt gttgtaaact tttgggtcag tgtctttgac
    34561 aaaaacctga gtatgattgt ctaactcttt aaatagataa tcttttggtt gcactttaat
    34621 agcatctcct gtcttacttt tatcaaggat taaaaatccg atttcgttag ctccttcttt
    34681 taaggggaca tcaacataag ctccataagg ccctttatgt gacaagtcaa gtccatttgg
    34741 ccagtcggtc gttggggttt tgacatcttt aaaggtccag acagctaagt tatcgtagtg
    34801 tcccgattga ttgtggtagt tgattcgaag gtaacctttt ttcaaaggtc gataagcgtg
    34861 tgcatggtaa ttctcgtcta tccaaacttc attcattttt ggcgtgagaa gcgagatgtg
    34921 ctggtccttt gaaagattct ctccagcttt attattaatg agataagaca cttgctggcg
    34981 gtgtttagct gctagtggca catctagata atagccatag tcatcttttt tcgcttttgt
    35041 catggtgata gcaccatttg gccaatcctt tgaaggttga tccacatctc cccacaccca
    35101 aagtcccaag cttcctagcg actcaccagc tggcaatgtt ttaaaatgca tacgcaaatg
    35161 atgctcagca atactagcag gattagctga cgagctgtct aaaactggtt tagcctcctt
    35221 gctagacgat tgaaaaccat catcagattt agcattgcca tctccttgtt gagcttcatc
    35281 gcgggctagt ccaacaatgg ttttagcagc aacttgatgt gttaagatac taggggtgca
    35341 ccctaacacg acagtcccag ttgcagcgat tacaaaacct atcccccact tttttaacag
    35401 atactgatag cgctttgatc cttggttgac tttctttttc ataagacctc catttagtat
    35461 aacattcaaa caagactatc ttatcacatt gcgcaagcgc ttgcaagaca tgccgcactt
    35521 caacttagaa cacagctcaa ataatgacta tcacccctta ataggatctc aaaaattaaa
    35581 cagccaaaac gagtttccac tcgcttggct gttgggtaaa ctcaaatcac atacaactgc
    35641 taggccttca gtttgagaca aaaggcatcc caaggttgta agtgcttggt ctctaatacc
    35701 gtgtccacat ctgtattggt gatgatcact tgtgcgcctg ctaagtcttt ggcaaagact
    35761 tgctcctcat cagacacatt gacaacaatt acatacgtct cttctccaag ctgacgctga
    35821 taagcaaaca ctttatcagc tgttggcaag aggtgataat ccgcttcaac tagccagtcc
    35881 tgctccttac gcaaggcaat caatttttgg taggtgtaaa aaatagagtc tggatcagca
    35941 agggcatcgg ccacattgat gtcttggtag ttggggttga ccggcaacca agtctctttt
    36001 gcttcagaaa agccagcatg tgtgtcctta gaccactgca tcggcgttct agcattgtct
    36061 cgtcctacct tacggatgct atccatcaca cgcgcagctg acactccatt tcccatagct
    36121 tccttagcat agttaaggga ctcaatatca ttaacctcgg ttaagtcttt aaaaggataa
    36181 ttggtcatgc caatctcttc tccttggtaa atgtaagggg ttcctcgcat caaatgcagt
    36241 aaaatagcta aagccttggc tgatttttct cggtaagtgc tgtcattgcc ccaaatggat
    36301 aagacccgtg gcaagtcatg gttattccaa aaaagcgaat tccagccttc tcccaacttt
    36361 aattttgtct gccacttgct aaaaatagct ttcagagcag gcacgtctaa ttctttggca
    36421 taatcccact tgggagcgtc aggtttatgt tgaagaccca catgctcaaa ttggaagacc
    36481 atggataact ctttattttc agggcgagaa tactggcgag caatttcagg cgttgctccc
    36541 caagtctcac cgacagtcat cacgtcatga ttgccaaagg ttgcttgatt catttctttg
    36601 aggtaatcgt gtaaccgcgg cccgttacct gtgatttcca agtcaggaac cttcccaatc
    36661 aggtcaatca cgtccatccg aaaaccacct atgcctttgg caatccagaa attcatcata
    36721 tcgtaaattt tatgacgcaa atcttcattc tcccagttga gatctggctg acgtttgcta
    36781 aaaaggtgca aataatattg acctgatgca ttatcatatt cccaagctga gccactaaaa
    36841 atagaagtca aatcgttagg ttcatctcgc caaatataaa aatcacgctc aggactatta
    36901 gggttttccc tagcttcaac aaaccaagca tgctcatcag acgtatggtt gaccaccaag
    36961 tccatgataa tcttaatgcc tcgctcatta gctgctgcta agagctcatc catatctgcc
    37021 atgtctccaa aaacatcagc aatcgcttca tagtcagaga tgtcatagcc attgtcatcc
    37081 attggacttt ggtaaacagg agataaccaa atggctgtaa tgccaagttt ttgcaagtag
    37141 tccagttgac tggtaatgcc ttttaaatca ccaataccat tgccattggt gtctttaaag
    37201 gatctcgggt aaatctgata aatcgtagct ttatgccacc agtgtttctt cattattctt
    37261 ctcctattaa tcattcattc atcttttatt ttaacgtttt ttctcttttg gtgcaatcgt
    37321 ttgcgcaaaa tgacatgata aaaaggttgg aacccaacct ttttatgaat atcgcttata
    37381 ccttaacgaa tagcttgttc ggtatctctg tcaaagaaat gccctttagc cacattaaag
    37441 gtcaagctaa cttgctcccc tggactatgg aaatcacgcg catctacacg agaagcaaac
    37501 tcagtttgtc caagcttgac atagagcatc gtctcagagc ccagtaactc agaaaccaaa
    37561 acttctgctg tgacagttgc acttggataa gtatcatgca cgatttgtct gctagaaatg
    37621 tcttctggac gaataccaaa agtgactttt ttccccttgt aaccagcagc ttcaagcatt
    37681 tttgcttgac cttcaggaat cgcaatagca agaccatctt cactcacaat gcggccatct
    37741 ttaacttcca cttcaaagaa gttcatggca ggacttccga taaagccggc aacgaattta
    37801 ttagctggaa ggttatacaa ttcttgtggc gagccgactt gctcaatttt accaatcgtt
    37861 ccattacctt gagggttttt agtggcactc atgataacga tacggtctgc caaggtcatg
    37921 gcttctgtct ggtcatgggt aacgtaaata gtcgttgagc caatcctacg atgaatcttt
    37981 gcgatttcag cacgcataga gacacgaagc ttcgcatcca agtttgacaa aggctcatcc
    38041 atcaagaata ccttagcatc acggacaata gcacgtccca tggcaacacg ttggcgttgt
    38101 ccaccagaca ggtcagccgg tttacgctct agaaattcgg tcaaaccaag gatctgcgca
    38161 gcttccttga cacgacggtc aatatcatct tttttgtact tacgtaattt caaaccaaag
    38221 gccatgttat catacacggt catgtgtggg taaagggcgt agttttgaaa gaccatggca
    38281 atatcacggt ctttaggaga cttgtcattc accacttcgc caccgatttt taactctcct
    38341 tcagaaatgt cctcaagacc tgcaatcata cgaagagtag tcgatttacc acatcctgaa
    38401 ggtccaacaa agacgataaa ttctttatct ttgatgtcca agtcaaaatc ttcaacggca
    38461 taatgagtag tatttgggta ttttttatag atgtgattta gatttaattc aaccatgtgt
    38521 aactcctatt tagccagcaa acgttctagc tgactgcaaa gctagaaacc gctgatatct
    38581 tttatatgat gcttttatta taacaaaaat agcgctttca aaacagagac aaagcgacca
    38641 aacttctttg ggcaacttgc acaatagcag gactagtcaa gtcgtaaagg cccataaaac
    38701 aagaaaacca tgtaaacaca ggccggtcac aggagccaaa acaagctgaa cgatctatca
    38761 tcctccttat cagctacagt ccaggcagca aaaaagaaag ccctgtggct ttcctaatat
    38821 ttcaacaaaa agagatgagc aaaggctaaa tcatccaatt gcttcaagta tagtcctgat
    38881 tgctgagcaa atttatcaag tttgtattgc aaggagttac ggtgaatata caagcgctgc
    38941 gctgtctgca ccagattgcc gtgttctgac catagagcgt gaaccacatc ggccatatca
    39001 ctttgaggac ttaggaattg gtgaaactga cgcgtcaatg ccaaaaaagt gtggtgcgac
    39061 agcaaagacc acagcatcag tcctgaaaat gttaataatt ttctgcctga ttgttgcctt
    39121 aaataggccg ttaacagctg acattcctcc tcaaaacact ctctcaatgt acccgcagct
    39181 acttgatacc aggcatttcc aacaaacatg gttaaggcca aaccaaaatc actttctagc
    39241 gttggcaaga gatcttcaag ccagcgcaag acctttattg agattgcttg tcggcataaa
    39301 aatgccgtct gagttgcact gataggcaaa atgacctcaa gccctgcaat catctgttgg
    39361 agcaactcaa ctaagtcagc tggtaaagcc tgctgatgat tgaggtaaat gaactgagaa
    39421 gtctcaaaca gctgaggggg attgccctga tgatcaagca aataccgctg ccaaggtgac
    39481 cctagcggct gcaagacctc acactgaccc agtcccacct caagtaataa gcgctctttt
    39541 tcggataaac atgatttggg aaaatgcaca tattggtccc cttctttgac actcacccac
    39601 tctttatctc ctaacggatg agggcctact tgcatctctg gaaaatagtc ttttagctcc
    39661 atagccattc ctttcatgac ggtctttaaa ccattataac acatgactct ttatcacaca
    39721 gttcggtttg ttatcagcac gattttgtat tttctgactt tctaatcatt aaagctaaat
    39781 aatggttatt catttttagc aagaacattc aatcaaatag ctatttatcg gaatattaat
    39841 ttatgtttat actaaaacag gtattatttc tcttttttca ttatcatgac attatcatta
    39901 agatatcatt taaaaaacaa ttattaggtt tttgtttgta tctataaaat tattatgtta
    39961 ttctaataat ggggattgaa acttaacttt taggaggttt ctatgaaaaa ttacttatct
    40021 tttgggatgt ttgcactgct gtttgcatta acatttggaa cagtcaagcc tgtccaagct
    40081 attgctggac ctgaatggct gctagaccgt ccatctgtca acaacagcca attagttgtt
    40141 agcgttgctg gtactgttga ggggacgaat caagaaatta gccttaaatt ttttgaaatt
    40201 gacctaacat cacaacctgc tcagggagga aagacagagc aagacttaaa tccaaaatca
    40261 aaaccacttg ctacagataa aggcgcaatg tcacataaac ttgaaaaagc tgacttatta
    40321 aaggctattc aagaacaatt gatcgctaac gttcacagta acgacggcta ctttgaggtc
    40381 attgattttg caagcgatgc aactattact gatcgaaacg gcaaggtcta ctttgctgac
    40441 cgagatgatt cggtaacctt gccgacccaa cctgtccaag aatttttgct aagcgggcat
    40501 gtgcgcgtta gaccgtatca acctaaagcc gttcacaact cagctgaacg cgttaacgtc
    40561 aactatgaag tgagctttgt ctccgaaaca ggaggtttag actttacacc gttgttaaga
    40621 aaccaatacc atttgaccac actggcagtt ggtgactctc tttcatcaca agagttagca
    40681 gcgattgccc aatttatcct atcaaaaaaa tatccagatt atatcattac aaaacgtgac
    40741 tcctcaatcg tcactcatga caatgacatt ttccgtacga ttttaccaat ggatcaagag
    40801 tttacttacc atatcaaaga ccgggaacaa gcttatgaga tcaatcctaa aacaggtatt
    40861 aaagaaaaga tgaacaacac cgaccttatc tctgagaaat attacgtcct taaaaaaggg
    40921 gaaaagccgt atgatccctt tgatcgcagt cacttgaaac tgttcaccat caattacgtt
    40981 gatgtcaaca ccaacgaatt gctaaaaagc gagcagctct taacagctag cgaacgtaac
    41041 ttagacttca gagatttata cgatcctcgt gataaggcta aactactcta caacaatctc
    41101 gatgcttttg gtattatgga ctatacctta actggaaaag tagaggataa tcacgatgac
    41161 accaaccgta tcataaccgt ttatataggc aagcgacccg aaggagagaa tgctagctat
    41221 catttagcct atgataaaga tcgttatacc gaagaagaac gagaagttta cagctacttg
    41281 cgttatacag ggacacctat acctgataac cctaacgaca aataaccacg atcttctaaa
    41341 acgatgagat taactgacaa aaaaagcaag caacacgcta tcaacagttg cttgcttttt
    41401 tctaacctct tagttgtaga gactagtgac atttcgtgtc taaaataatc gtaactggtc
    41461 catcattgac gagactaacc tgcatatctg ccccaaaaac gccacgctca actggcacaa
    41521 actctgccaa ttgttcatta aagctatcat acaactgact agccaaatct ggcttagcag
    41581 caccagtaaa ggcaggacgg tttccctttt tggtgtcagc ataaagggta aattgcgaca
    41641 cagataagat actgcccttg atgtcttgga tagactgatt catcttgcca tcagcatctg
    41701 aaaaaatgcg catgttgact atttttcgca cagcgtaagc caaatcttct gcattatcat
    41761 ctggtcccac acctactaac aacaatcctt gattaatagc gccagcaatt ttcccatcaa
    41821 tagaaacaga ggcctctttg acccgttgca agacaagttt catggtttta tcctttctta
    41881 accattggtc cgcttcacgc tataaacatc tggaactgcc ttgatttttt cgacaacagt
    41941 ggtcagatgc gtcagatttg gaatgccaaa gctcacgtga atattagcaa acttcatgtc
    42001 tttggtcggc tgagcattga ctgtcgatat gctcttggtt gagtttgata aaatttggag
    42061 cacatcatta agcaggccac tacgattgag cccatagata tcaatttcag cctgataatc
    42121 tttactcgaa ttgtccaaat cccactcgac ctcaatcaag cgttcttggt agccatcttg
    42181 actcttaatg ttatgacagt ccgatctgtg aatcgcaatg ccacgccctt tggtaatgta
    42241 gccgtcaata ggatcaccag gtacaggatt acaacacttg gcaatccgca tcaagaggcc
    42301 tgatgctcct tggataatga ctccattttc actgcgaacc ttgagcacat ctttgttttc
    42361 gtgtttgacc tcaccgccct taaccaattc ttcagcttct gctttagcct tggccctttc
    42421 ttcttcacgg cgctcttttt cggttaactt gttaaaaaca ctgataggac taatgtcacc
    42481 aaacccaacg gctgcataga gcgattcttc actcttcaca ctgacttttg gaaggatcgc
    42541 ttcaatgcgt tttttgtcaa ggtatttatt ggcaacgtag ccctgctctt gaaaataaga
    42601 caccaacaaa tcacggcctt tattcactga caattccttg tcttgatttt taaagaactg
    42661 acgaattttg ttgcgagcct tattggtttt gaccagtttt acccagtctc gactagggcc
    42721 aaaggaattg gcattggtga tgatttcaac cacatctcct gtttttaact tggcagtgag
    42781 aggaaccata cgcccattga ctttggcacc tgttgctttt tcaccgattt gcgtatggat
    42841 cgcataagca aaatcaatag gacctgattc ttttggcaac tcctgaacgg cccctgtcgg
    42901 tgtaaagaca taaatccgtt cagaaaaaat atcttctttg accgaatcca caaagtccac
    42961 tgcatcgcca tttgaggcat cttgcaattc taccagctct ttgatccagt tcatgccaac
    43021 ggcttgctca gcctgattga ccttaccacg cacgcctttt ttataagccc agtgtgcagc
    43081 aaccccgtac tcagccactt ggtgcatttc cttagttctg atttgaatct caataggtcc
    43141 ttttggccca tacacagtgg tatgaatcga ctggtagcca ttagctttag gagctgcaat
    43201 ataatccttg aagcggcctg gcatggggcg ccaaagctcg tgaatatagc caaccatagc
    43261 atagacatcg ctttgcgttt ccatgacaca acgaatggca atcagatcaa aaatctgatc
    43321 gaaacgtttt ttcttgtccc gcattttccg ataaatcgaa taaatgtgtt ttggccggcc
    43381 atacacatct ccaaacaagc cttgttgtgt cgtataggtt ttgaccttac tgacaatagc
    43441 ctctaccaaa gcttcacgct cgcgacgttt ttctttcatc atatgggaaa ttttgtaaaa
    43501 ttcggtttca ttgaggtaac gaaaagccaa atcttctagt tcccatttga tgcgactaat
    43561 tcccaaacga tgcgccaagg gggcatagat ttccatggtt tcgcgcgaaa tgcgctcttg
    43621 tttgtccttg cgcaaatgtt tgagggtgcg catattatgc aggcggtcag ccaatttcac
    43681 caaaatcacg cgaatatctt tggacatagc catcagcatt ttgcgatggt tttcggcgag
    43741 ttgctcctca tgagatttgt actcaacttt acctaacttg gtgacaccat caacgatatc
    43801 acgagcatct tggccaaagt ctgcttcgat ctcatctaag gtaatatccg tatcttctac
    43861 gacatcatgt aaaaagccac aagcaactgt cacagcatcc agatgcaaat cagccagaat
    43921 ccccgccacc tgaatcggat ggacgatata gggttcgcct gactttctca cttggtagaa
    43981 atgggccgct gttgcatatg ctaaagcctt tgccacaaaa gccacatcag ccttggtcat
    44041 ataggtggcc gctaaggcaa tgacttcttc tcctgttacg ttcattattt ttgccatttc
    44101 gttcctcatc tagcatttct tttccctatt ttaacacttt acacacaaaa gcaaaaggca
    44161 gaatctgcta agaaagcgct tagtgtgacc ttttcttaga aaacggttag tgagctgctt
    44221 ttgatatctt ttgggatctc tcaggcgtga gcatgatacc aacggccagc tcccgaccaa
    44281 aaatagagag aaccaagggg ctctctctat tatgtttgct tatcagtaag gtctctcaat
    44341 tcagaggatt agttgttttc tttgcgtttt gtaacggcta ggacaccagc tgttgtcatt
    44401 actgctactg ctgctgctgt aaagaatggg ttggcttgct caccagttgc tggtagacgt
    44461 ctgtggttgt tagctacagg tgtcttagcc atattgccat tgcggcgttc tggcgtttgg
    44521 ttagcttctt tgtcagcagg tttttctggt gttggtgtca cttct
//
LOCUS       DAUGOH010000014        43073 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUGOH010000014 DAUGOH010000000
VERSION     DAUGOH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43073
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.014"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..163)
                     /locus_tag="VH957_000789"
     CDS             complement(<1..163)
                     /locus_tag="VH957_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8558716.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKK"
     gene            complement(232..303)
                     /gene="shp3"
                     /locus_tag="VH957_000790"
     CDS             complement(232..303)
                     /gene="shp3"
                     /locus_tag="VH957_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEQ8558717.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            383..1234
                     /gene="rgg3"
                     /locus_tag="VH957_000791"
     CDS             383..1234
                     /gene="rgg3"
                     /locus_tag="VH957_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEQ8558718.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDKDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     SLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1487..5026)
                     /gene="smc"
                     /locus_tag="VH957_000792"
     CDS             complement(1487..5026)
                     /gene="smc"
                     /locus_tag="VH957_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEQ8558719.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHTAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKCVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGTNRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5027..5719)
                     /locus_tag="VH957_000793"
     CDS             complement(5027..5719)
                     /locus_tag="VH957_000793"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEQ8558720.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVVIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6151..6960)
                     /locus_tag="VH957_000794"
     CDS             complement(6151..6960)
                     /locus_tag="VH957_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8558721.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(6964..8316)
                     /gene="vicK"
                     /locus_tag="VH957_000795"
     CDS             complement(6964..8316)
                     /gene="vicK"
                     /locus_tag="VH957_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEQ8558722.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8309..9019)
                     /locus_tag="VH957_000796"
     CDS             complement(8309..9019)
                     /locus_tag="VH957_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8558723.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9181..10215)
                     /locus_tag="VH957_000797"
     CDS             complement(9181..10215)
                     /locus_tag="VH957_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8558724.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10271..11518)
                     /locus_tag="VH957_000798"
     CDS             complement(10271..11518)
                     /locus_tag="VH957_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ8558725.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLKKADFAVL
                     SSGTTGKAKLFWRRLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPVGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(11475..12623)
                     /locus_tag="VH957_000799"
     CDS             complement(11475..12623)
                     /locus_tag="VH957_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEQ8558726.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNTVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13018..13167)
                     /locus_tag="VH957_000800"
     CDS             complement(13018..13167)
                     /locus_tag="VH957_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEQ8558727.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(13368..14153)
                     /locus_tag="VH957_000801"
     CDS             complement(13368..14153)
                     /locus_tag="VH957_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558728.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESAGS"
     gene            complement(14155..14973)
                     /locus_tag="VH957_000802"
     CDS             complement(14155..14973)
                     /locus_tag="VH957_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEQ8558729.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKVVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(14975..15967)
                     /locus_tag="VH957_000803"
     CDS             complement(14975..15967)
                     /locus_tag="VH957_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8558730.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNDVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHELSLDIQYDSSRYQTADIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(16107..18050)
                     /gene="thrS"
                     /locus_tag="VH957_000804"
     CDS             complement(16107..18050)
                     /gene="thrS"
                     /locus_tag="VH957_000804"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEQ8558731.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(18472..19806)
                     /locus_tag="VH957_000805"
     CDS             complement(18472..19806)
                     /locus_tag="VH957_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8558732.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19808..20806)
                     /locus_tag="VH957_000806"
     CDS             complement(19808..20806)
                     /locus_tag="VH957_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8558733.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20937..21938)
                     /gene="ccpA"
                     /locus_tag="VH957_000807"
     CDS             complement(20937..21938)
                     /gene="ccpA"
                     /locus_tag="VH957_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEQ8558734.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22112..23197
                     /locus_tag="VH957_000808"
     CDS             22112..23197
                     /locus_tag="VH957_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8558735.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLIKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23246..23911
                     /locus_tag="VH957_000809"
     CDS             23246..23911
                     /locus_tag="VH957_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8558736.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEDDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23922..24299
                     /locus_tag="VH957_000810"
     CDS             23922..24299
                     /locus_tag="VH957_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8558737.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24444..25370
                     /locus_tag="VH957_000811"
     CDS             24444..25370
                     /locus_tag="VH957_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8558738.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25581..26264
                     /locus_tag="VH957_000812"
     CDS             25581..26264
                     /locus_tag="VH957_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEQ8558739.1"
                     /translation="MEWIKLIGIVIIVLGFILKCDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQALTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYGGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26264..27190
                     /locus_tag="VH957_000813"
     CDS             26264..27190
                     /locus_tag="VH957_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEQ8558740.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27240..27887
                     /gene="pcp"
                     /locus_tag="VH957_000814"
     CDS             27240..27887
                     /gene="pcp"
                     /locus_tag="VH957_000814"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEQ8558741.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERIAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28005..28724)
                     /locus_tag="VH957_000815"
     CDS             complement(28005..28724)
                     /locus_tag="VH957_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEQ8558742.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28730..29197)
                     /gene="smpB"
                     /locus_tag="VH957_000816"
     CDS             complement(28730..29197)
                     /gene="smpB"
                     /locus_tag="VH957_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEQ8558743.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQESDIKKQMKHYNAR"
     gene            complement(29200..31533)
                     /gene="rnr"
                     /locus_tag="VH957_000817"
     CDS             complement(29200..31533)
                     /gene="rnr"
                     /locus_tag="VH957_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEQ8558744.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNGVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINPQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKVEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYNQPSQEKRDHFAQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVASVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGIK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31627..31863)
                     /gene="secG"
                     /locus_tag="VH957_000818"
     CDS             complement(31627..31863)
                     /gene="secG"
                     /locus_tag="VH957_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEQ8558745.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31909..32055)
                     /gene="rpmG"
                     /locus_tag="VH957_000819"
     CDS             complement(31909..32055)
                     /gene="rpmG"
                     /locus_tag="VH957_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8558746.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32052..33245)
                     /locus_tag="VH957_000820"
     CDS             complement(32052..33245)
                     /locus_tag="VH957_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEQ8558747.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33367..34869)
                     /locus_tag="VH957_000821"
     CDS             complement(33367..34869)
                     /locus_tag="VH957_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEQ8558748.1"
                     /translation="MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISEMGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQSPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
                     QAATKKANRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35059..35652)
                     /locus_tag="VH957_000822"
     CDS             complement(35059..35652)
                     /locus_tag="VH957_000822"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEQ8558749.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR"
     gene            complement(35649..36476)
                     /gene="mutM"
                     /locus_tag="VH957_000823"
     CDS             complement(35649..36476)
                     /gene="mutM"
                     /locus_tag="VH957_000823"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEQ8558750.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLITKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(36648..37514)
                     /gene="rgg2"
                     /locus_tag="VH957_000824"
     CDS             complement(36648..37514)
                     /gene="rgg2"
                     /locus_tag="VH957_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEQ8558751.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37603..37671
                     /gene="shp2"
                     /locus_tag="VH957_000825"
     CDS             37603..37671
                     /gene="shp2"
                     /locus_tag="VH957_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEQ8558752.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38585..38854
                     /gene="stcA"
                     /locus_tag="VH957_000826"
     CDS             38585..38854
                     /gene="stcA"
                     /locus_tag="VH957_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEQ8558753.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39202..39600)
                     /locus_tag="VH957_000827"
     CDS             complement(39202..39600)
                     /locus_tag="VH957_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEQ8558754.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDTAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVLPSLNDKSA"
     gene            complement(39693..40765)
                     /locus_tag="VH957_000828"
                     /pseudo
     CDS             complement(39693..40765)
                     /locus_tag="VH957_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(41168..41362)
                     /locus_tag="VH957_000829"
     CDS             complement(41168..41362)
                     /locus_tag="VH957_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ8558755.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMVGAAQGVIVCAQTGVFIP
                     LQGYLLCGAAGAATNIIWPH"
     gene            complement(41656..41856)
                     /locus_tag="VH957_000830"
     CDS             complement(41656..41856)
                     /locus_tag="VH957_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ8558756.1"
                     /translation="MTTMKELTISDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            complement(41869..42085)
                     /locus_tag="VH957_000831"
                     /pseudo
     CDS             complement(41869..42085)
                     /locus_tag="VH957_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
     gene            42402..42970
                     /locus_tag="VH957_000832"
                     /pseudo
     CDS             42402..42970
                     /locus_tag="VH957_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014572446.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        13016 a         9131 c         7504 g        13422 t
ORIGIN      
        1 tttttttatg tttatattca tccagaactc ctatgttgtg atttagatat tcaaataatt
       61 catctgatat agaatgttca actggattac caagcaatgc agaatacata aatttcatcc
      121 tcctacgttt aattagttta ctactaacat aaagtacaag cattacacag agctaaccat
      181 tacctataag tctttagagt atctaaagac ttaggtgtac acctaagtaa cttacccacc
      241 aacaataatg ataatatcca ttgctaaaat taaaatcggc aaaaattttg aaattttctt
      301 cataagcgga cttcctttca gtttttattt attgtacaat aaataaaaac tgaattgatt
      361 tttgttggga aagtgggaaa atatgaaatc aaaacttggt gccacactta gaaaagttcg
      421 aaaaggaaag caaattagtc tgtgcttcgt ggcagatgaa cacctttcaa aatcacaaat
      481 ctctcgtttt gagcgcgggg agtcagagat atcgtgtatc cgactgatca atattctaga
      541 caaattacac attactttgg atgagtttct tattttacat gataaagact ataccaattc
      601 cgaaacattt gctaacctgg tacagtatat tcgtaagcaa tattcatcac aaaatatcaa
      661 taatatagca tgtttacttt ccgacacttc tgattacact ctgaattctt ttgagaaaac
      721 aatggtaaag tccattttac acacaatgga ttcaagcatc attccatcag atgatgaatt
      781 acttcaacta acagattatc tctttaaagt tgaaaaatgg ggctactatg aaatcctttt
      841 gttgggtaac tgtgtacgaa caattaacta caactcctac ttcctattga caaaggagat
      901 gttaaataat tacatttact cttcacggaa caaaactaat aaacgaattg tcactcagct
      961 tgctataaat tgtttcattc ttagtatcaa taaggaggaa ttttctaatt gctcctattt
     1021 aattgatgag ataaaatcat tattagataa tgaattaaac ttctatgaac agacagtttt
     1081 tctctatgca acaggttact ttgaatttaa gcgccaatta gaaactggag ttgaaaagat
     1141 gaaacaagcc atacaagttc ttgatatttt aaatgaagac aagttaaaat tacattacgc
     1201 tgaccatttt gataaactag tcaacaaaga ttaagtaaaa tcattcttta ccttttaacg
     1261 aaacgccaat caagggtgtc tcaataaaaa atcatctact ctgacaactt ttctctttta
     1321 cctatcgaca gctaaaaagc cttggaaact gctatttcca aggctttctt tgtactctat
     1381 tgtatcaatt agcttattcc gatttctgtt gctattagtt taatcatgaa atctcctaac
     1441 ttatggccga acatccaaaa aaacagaagg aactcccttc tgttttttaa ttggtcatct
     1501 cttgagcttc ttttaatttt acagatacaa ttttagagac ccccgattcc tgcatggtaa
     1561 ttccataaat actatctgct gcagccattg ttcctttacg atgggtcacg acaataaatt
     1621 gactatcttt gtcaaagcga ttgaggaaat ccccaaagcg cttaacattt gcttcatcaa
     1681 gagccgcttc tacctcatct aaaatcacaa acggaatcgt tttaacacgt ataatagcaa
     1741 acaataaagc cagtgctgac aaagcttttt ctccgcctga catcaagtta agagattgaa
     1801 ttttcttacc aggaggctgc acagaaatct ctataccagc agacaagagg tctgtttccg
     1861 ttaaaactaa atcagcagaa cccccaccaa acatctgagt aaaggtttct ttaaaacttt
     1921 tttgaattgc ctcaaaagtc actttgaaac gagccttcac ttcgctatcc atactattaa
     1981 tagtctctag caaaagattt ttagcttttg tcagatctgt cttttgactt gttaaaaaag
     2041 tcaaacgctc atgcacttcc tcatactgat taatagcatc actattaatt ggtcctagtg
     2101 cacgaatagt cttttgtaaa tggtgtaatt tttctttggc actttctaag tgatcaatac
     2161 tatttgttac ctcctttgcg tctgctagtg tcatttgaaa atcttctgat aaacttttag
     2221 cataggctcg taagcgatta gccacttgct ctaaatgtgt ctctaacttg gtttgacgac
     2281 gaataaatgt gtcatttttt tcgctttctt tggttatttt ttctgctgtt tcttctaagc
     2341 gggcctcata gtcctctatt tcaaatctta attggactaa acgtttttga gcaccagact
     2401 tatgctctgt ggcatcttgt aactgttttt gccactgggg tagtctttga atgctgtctt
     2461 gacttacgtt attgtttagt atgctttcaa gtttgagaat attttgctgg cattgcttca
     2521 gctgagttct tagacgagat tgattagctt gctcaaattt cttttcatta agtaaatctc
     2581 tttcttgcaa acgagcttga gataaagctt ggtgaatgtt ttgtgttttt tgcctaatca
     2641 aatctttgtt ttctttgata tcatcaatat cacaagttaa ggcatttttt ttcttagcaa
     2701 tagctgttaa tgcttcttca atacgagctt gttctgccaa taaagattca tcagaatgag
     2761 tcgtctgact ttgatcaagg gcagctaaca aagcctttga atcttcttgt ttttcttgca
     2821 attgctgata agccatttga gctctttgtt cagctaagcg tgcctggtca ccggctaatt
     2881 tcaattgtgt cagttcttct ttttttgcta tcaaatcgct ttgcaaggca gctacttctt
     2941 tttcagttat ttttaattgc tcaactaatc gcgttaattc ctcactgatt tgttctaact
     3001 ctggtttgat aaaagttgta ttgctttgtc tattagttcc tcctgaaaaa gaaccacctg
     3061 gtcgtaattc tgttccatca agagtaacaa ttcttacctt atatcctaat aagcgcgctg
     3121 caatattagc ttgatcaata gtttcaaaga tagcagtact agataaaagg ttttggataa
     3181 tagctgaaag actatcatca tagcgaacca atgattctgc agttcccaga taaccttcac
     3241 aagtcgctaa ttgacgatga tagtgttctg ataatgatct agcctttata gtagttaaag
     3301 gtaaaaaagt tgctcgtcct tggcgatttt ttttcaaata agcaattgct ctttttgctg
     3361 cagcttcgtc tgttacaata atatgctgac tattagcacc taatgcaatt tcaagagctg
     3421 tttggtaatc agaatcaaaa gaaaggtgtt cactgactgc acctatgatc cctccaagct
     3481 ttttttgtga ttgaaggaca gctcgtactc ccgcatagaa ttgactatga cttttttgaa
     3541 tagattctaa gctagcctta cgagcttctt ttcctttttt ttgatccaac aagtcaaata
     3601 gtctttcttg attcagttgg taatctcttt ctaattcctg aacgcattta tcaccttctt
     3661 gataattttg gagcaacatt tcgacttgct ctttttgagc tttataatga gcttgagctt
     3721 tttgagactc gtcattaagt tgatcaagct tagtaacaag tagctgatat tcttgagccg
     3781 tatgttgacg agcctgtttt tctttgtcta aatgggcttt taaagctgtc agctgatttg
     3841 ataaggccgc ctctttttgc atcaataata caaactcttc tcttagagtt tccattaatt
     3901 ggtcgggatc acttgaaaaa cgctctaatg cattgctcaa ttcgtttaac tgttgtttga
     3961 catcacaaag ttgttgatca atatgcaata attgttctgt acgctgcttt tcttctgctt
     4021 gaaaaccatc caattgttct tgtaactgtt cgagatgttt tttggcttct gcctttttct
     4081 ctgcttcttg gccactttct agcttaacca attcaatttg cttttccaag tcagctatta
     4141 gcttggttaa ttctaataat gttgtttggg tttgatctga ctcttgacta agaacctgct
     4201 ttttttgctt gaatttttgg taatcttctt ccatagattg acgcttagcg taataagatg
     4261 ctaagtcttg ttgtaaagca gctaaagctt cagtatcttt agtctgtctt tcttgagcta
     4321 tatcaatatc tttgactaga atatctagtt gtagttgctt acgattggca tcaagttcta
     4381 aaaattgttt agctacttta gcttgctttt caagtggtgc caactgcgtg tctagctcat
     4441 aaataatatc ctctagacgg tctaaattat cttgagtttg atttaattta atctgagttt
     4501 cttttttacg tgttttatat tttaaaacac cagctgcttc ttcaaaaatg gcgcgccttt
     4561 cttcaggttt actattgaaa atttcctcta cacgaccttg agaaataatg gagaaagaat
     4621 cacgaccaag ccctgtatcc ataaacaaat catgaatatc acggagcctt accttgcgac
     4681 catcaatcag atagtcacta tctccatttc ggtaaatatg cctttcgaca cggatttctt
     4741 tcttggcagt ttttataaaa tgatcggaat tatcaagaac aaccgctacc ttagcatagt
     4801 ttagaggatt acggttttgt gtcccagcaa aaatgacatc tggcatcttg cccccacgca
     4861 gatttttagc acttgattct cctaaagccc aacgtaaact ttctgtaata ttacttttac
     4921 ctgaaccatt tggtcctacg actgcagtta ctcccttatc aaattcaatt ttagtcttgt
     4981 ccgcaaagga cttgaaccct tccaactcaa tttcttttaa aaacatctaa acctcactaa
     5041 gttgggcaag ggcattttta gcagcatctt gctccgctaa ttttttagac ttacctaaac
     5101 ctttactaag gacagcacca ttaacaacta tcgatacctc aaattgttta gcgtgggcag
     5161 gtcctttctc actaatgact tgataatcaa taaccacatc accttttgtt tgcaaaaact
     5221 cttgaagaca agttttatag tctttaaccc tttcaaaatt ccctttttcc acctgaggaa
     5281 tcatgacttg tttcaagaag cgacgtactg catcaatccc cttatctaat aaaagagcac
     5341 ctaaaaaggc ttcaaataag tctcctaaaa tagtatcacg acggcgacca cctgactttt
     5401 cctcaccttt tcctagtttg atataagcgt caaaagaaca aaatcgtgaa aaacctgcca
     5461 agctttcctc acgtacaatc atggaacgta acttagacat atctccttct gtctttttag
     5521 gatactttgc aaataaatac tctgaaataa tcaattgtag aacagcgtct cctaaaaatt
     5581 ccaagcgttc attatgtgaa acgtttagga gacgatgctc gttagcgtaa gaggtgtggg
     5641 taaaagctgt ttctagtaaa gtcaaatcat taaattgaat atcaaaagat gttgagagta
     5701 actcttcaag ctgtttcata aaaaatccct ttcacatttg tcagtagacc ttatttagta
     5761 taccaaaaat ccacctagaa aaccgactct aagtggattt ttcgtgattt attaaacatc
     5821 ttaaataccc gtcaaaggaa actttctcat acaatcaaaa gactctacac tatctgaggg
     5881 gaatttccca ctacagatag tatagagcta ttttgttttt agtctgaaca actaaaaaac
     5941 taccttatct ttataatcct caacaccttt gataaataga tcagacaagc caaaactaca
     6001 ggctaattta agtctattga tgctctaaag gatgaccaat gagagttcat tgaactcaga
     6061 agacaatacg ctttaagaca tcaaaaaata gccctgactg gtatatcacc aatcagcgct
     6121 actttgtata ttctctttta gtttcttatc tcaaatatca gttaatggac aagcagtatc
     6181 tggagaggta tcatggaccg taaagtctgt acctactgct aaatctgcca tagccagttg
     6241 attgaccatc gtcatatgcg ctaactcttt gatgttattt tctttactca gatgacctag
     6301 gtatattttt ttggtattgt accccaggct tctaatcatg gctcccgctc catcttcatt
     6361 tgataaatgt cctaaatcag ataaaatacg ctgcttcaag ctccaaggat aagagcctga
     6421 tctcaaaatt tcaatatcat gattggattc aatcaagtag ccatctgcat tttcaataat
     6481 acctgtcatc ctatcactga catatcctgt atctgtcaac atcacaaaag acttattatc
     6541 tttcataatc cgataaaatt gaggatcaat agcgtcatgg ctgactccaa aactttcgat
     6601 atcaacatct ccaaaggtca aaactttatc cctttggaaa atatgttttt gtgaggcatc
     6661 aagcttacct agcatattgc actcatccat cagctgccat gttttttcat tagcatagat
     6721 atccaaatgg tatttgcggg ccataacgcc tacaccctta atatggtcag agtgctcatg
     6781 ggtaatcaaa atagcatcca aatcctcagg tttgcggtca atttcagcaa gaagactggt
     6841 aattttctta ccagtaagcc ctgcatcaat caataagcgt tttttaggtg tttctaaata
     6901 aaaacaattt cctgtggacc cagatgctaa aatactatat ttaaaaccac tctcattcat
     6961 tgattagtct acatcttcct cccattcttc atagatggct gcatcttttt cataaggcaa
     7021 gacaatagta aaggtcgatc ctttaccata gtcactctta gcccagataa agccatggtg
     7081 ctgcttgatg atttctttag caatggcaag gcctaggccg gtccctcctt gggcacgact
     7141 tcttgccttg tctacacgat agaaccgatc aaaaataaga ggcaaatctg ttttagggat
     7201 acctagtcct tggtctgaaa tggaaataat taattgggta tctgttgttt tcatacggac
     7261 tgtaattttt ccaccatctg gagaatactt aatggcattg ttcaaaatat tctcgataac
     7321 ctgtgtcatt ttatcattat caatttcaag ccagacagag gtaatagggt aatctcttac
     7381 aatttcatag acttttcctg tacctgtatg ctgattttta accaaatcaa atctgtttaa
     7441 aatagaagtt ataaaagcag taaaattagt catctctact gctaattggg ttacttgatt
     7501 atcaatccga gacaggttta aaagatctga aatcatacgc atcatccgat tagtttcatc
     7561 aagagaaact tttatgaaac ttggagcaat atcttcttta agtgcacctt catcaagagc
     7621 ctccaagtag gatttaaccg aagttaaagg ggtccttaat tcatgactta cattagagac
     7681 aaaaagacgg cgttcacgtt cttctttttc ttgttctgtg gtgtcatgga gcaccacaac
     7741 caagcccgaa ataaaaccac tctctctcct attcaacgca aagcgcaaac gtaatgagac
     7801 aaactcaccc atatcatttc ggctattaac agttaccact ggtgttttgg ataccaaatc
     7861 acggtaggta tatgaagtat caccttctaa caaatctgta atgtttttct ttagtgcctc
     7921 ttctttactt aaatttaatt gcttgcgagc tgtctcgtta atcatgatga ttttaccaga
     7981 ccggtctgta gcaagtacac catctgacat ataagccaaa atacttgcca agcgattttt
     8041 ttcttgggca agattttcat gcgtcaagcg aaaaacatct gacaggtcat ttaactggtc
     8101 tgaaagctcc attaactcaa tgtctgcttt ttcgtcgatt atatcagtat agcgaccatt
     8161 aatcaagtct cggattttat ggctcatcat ccgaataata cgtgcatttc ggtagtcacg
     8221 caccgcaaga tggataaagt aaaaagcaac aaaaacaagt aagataagga tcgctaattc
     8281 aaatgtggat aagtttccaa tgatatctct agtcataaga tttcatgtag tacccaacac
     8341 cacgtcttgt taaaatatac tcaggacgac ttggtgtgtc ttcaattttt tcacggagac
     8401 gacgaacagt cacatcaacc gtgcgcacat cgccaaaata atcatatccc caaacaattt
     8461 ccaataagtg ttctcgtgtc atcacctgac ccatatggtt agctagatga tgcaatagtt
     8521 caaattcacg atgggtcaac tctacctctt gaccatgttt tttagcaaca aacgcatctg
     8581 gtaaaatctg taaattacca atggttagtt cctgtgtacc tgaagaagca ttttcttctg
     8641 caacagcagt ttcaatagtt tcggtacgac gcagatgagc cttgacacgt gccagcaatt
     8701 cccgattaga aaagggcttg gtcacgtaat catcagcccc aatttcaagt ccaataacct
     8761 tgtcaaactc actatcttta gccgacaaca taataatcgg gacatgactg gttttacgaa
     8821 tttccttggc tacttcaaga ccgtccaact cagggagcat caaatcaaga ataattaaat
     8881 ctggcttttc ttcttcaaaa attgttaccg cttcgcgtcc atcaaaagct gtaacaatgt
     8941 cataaccttc ttttgtcaaa ttaaacttaa taatgtcaga aatcggtttt tcatcatcca
     9001 caataagtat ttttttcatg tctatacctc agaaagttct tgtaattgat attacaattt
     9061 gtgatttttg tggttaataa aaaatcacaa aactatattt ttctaaatta tttctacctg
     9121 attataccaa aaattcagcc taattgacaa tgacgactac cgttacaaat agagtacttt
     9181 ctaaaaccaa ccctttatag gatgaatttg acgtttgaat tgcttagcag attttttgac
     9241 tctggcaaaa ctactcttgt tgtggtaagc aaaaagtcct ttggcattaa aataagagaa
     9301 cataaagtca tctttttgag ctctaaacca ctgacgaaat actctttttg gcgatcgaaa
     9361 tcctttaagg gtgtcccttc taaactgagg atcgtgacgg ctaatcggat caacatctaa
     9421 atcccaatgt ctaggaccat ctgtgccata gttaaaagat gcaccattga caattccttt
     9481 ttcggtcact acttctgcat caacttcatt aagaaaaaag cctgtgctat ctagaataaa
     9541 ttcggtatga aaccaaagaa gtacttttat attataggaa acttcttgac ttggaaaaat
     9601 gactttatta tcttcaaatc ttagtttatt atgtaacctg gcagaatcca tcaaggtata
     9661 atctggtgct tgccgccaca aacaaggccc ttttttagac ctcaaaaaaa gggccagagc
     9721 ttgggcgtct gtcatctcaa tcattttata atggtttctg atagattgag cttgttgact
     9781 agagatgaca taacgaaatt gatgcaaacg cttttcaagc tcacctgctt ggcttagtgt
     9841 tttgccagga aaagcttgat caactaagct agccaactct ttccaaaaca tatgatctgg
     9901 caatagagat ggatggaatc gggtgagtag cgtttgagtt tcatgcaact gaccacttag
     9961 ctcaaatggc atctctacca aatcaagaag aaacgttagt aactgcttag ctgattggtt
    10021 ttctttttca ataggccata ttacccagaa agttggagaa ccaagtcgat tatcaatgat
    10081 aggctcttta gctatagcac gaaatgcttg gtttgataaa cctgcgtttt gatagcattt
    10141 caaggcctga tagcgatcta agatagcttg tttcatggcc ttctcctcat cttttttgac
    10201 catattataa cacatctaaa gctgaatcgt cacttgtatc tcactataag caaaacgaaa
    10261 cctgaagtgg ttaactaagc cactgtttgg gtattttatt taaaagaact tctcgattaa
    10321 ttttaccatt atcttttaaa ggcaaacaat caatcacaag atagtacttg ggaagttgtc
    10381 cagagtttaa ataaagagct aaaaagtctt taataggtgc taggcaatcc ttcttagtca
    10441 aaactaatac taatattagg gtttcgtttt ctccttttcc tatctttaaa gcgtgcgctt
    10501 ctttgacgtt tggcgcttgg tgagcgagtt caactaggct aggcaggtgg catttcactc
    10561 ctcgttgatt aacccagtca tcttgtcgcc cttctaaaat taaacccact gggctcattt
    10621 ttcctaagtc tgagacactg tatggttgtg acattccttc tacactataa ggagtctcta
    10681 caaaaatttc cttatctttg aaactgatag acacatcagg aaagggctgt cctaccaaac
    10741 cattaatttt gacagcagct ctgccattac accacgttat aaaagataat tcactagccc
    10801 cgtagaaaat gacaatttca agctgaggaa attttttgta ataatgtctt agtaattctt
    10861 gtgatatcat ttgcgaagag gtcaataagt gagtcgcagt catgttgttc ttagtcaaat
    10921 aaggtagcaa gcgatttagg taggtcggta aaaggtaaag gtgactcacc ttttttgctt
    10981 gccataagct taaccacgtt ttcaaagaca gcttttggct taaaaccaga catcccccgg
    11041 cccatagttg agctaatgct aagttaagat tgccagtaaa actaaaacta ccatgtaaga
    11101 atagacaact attaccagtc ataccaaaca ccttattttg ataatcaaaa agtctcgtcc
    11161 aagttgatag acgacgccaa aataattttg ctttgccagt tgttcccgaa ctcaaaacag
    11221 caaaatcagc ttttttaaga agctcaccat cgacgtgttt tatttgctgc tgaaatgtac
    11281 ctgagatatt agggtgtaaa atgataggac aactgccttc ttttaatcct cgtaaaaaag
    11341 agagtaactg attaagatag cgactatgac tgatgatata tggtacactg tcttttattg
    11401 tctgatcctt tattaaaacc gcttgccata gctcttgata agtcaagctt atctgatcgg
    11461 ctacgatagc ttttttattt gggcattgct ttgcccaata ttctagcttt gtcagcatga
    11521 ctaaactcct tatgatattt tagtaaaaca gcaaaccctt ggccaccagc tgctgctata
    11581 gcagctattc catagcgtcc atttttaatc tctaaagccc tcattaagtg caatattata
    11641 atggctgctg aggcaccata gggatgacca taagctaatg caccaccaaa tatattatag
    11701 cggtccaata aatctggata atgggtttca aatagaccat caataacggc aaaggcttcg
    11761 ttccattcaa tcgctgtcat atctgccatc cctagaccat gtttttccaa aaggacttga
    11821 ctagccttaa tcaccattaa agggctacgc tgtgggtctc ctgctacttc taccacatca
    11881 atcagtttaa aagctgaagg ctgactactt agctgtaaaa aggcagcagc atcatgggtt
    11941 aggcaggcat tggctgcact aatcacgtga tcttctccta agataggggg tacctttgac
    12001 aacaccttac ttgacaagcg cggtcgaata ccttgatcac tggctcctgg caggtctaga
    12061 ataagatcag ctaacagggc ttgctcctgg caataactag ccttttgatg acttctcaat
    12121 gtccagtgat tcaaatactc ctttgtaaag ccatgctctc ttgccactcg ttctgcccct
    12181 tcaatcatcg caaaagggct gatactatct ggagaaaact gagctacctt gtaggctcct
    12241 tggcgccaat cagctgaagc atataccgat tcaggttgta aggagctgct ttcaatccct
    12301 cccactaaaa ggttgcttgc catacctgcc ttgattttag cataacccac ggaaagagct
    12361 gcaccagctg atgcacactg catatcaacc gtcaaagcag agacagattc tcctaaatga
    12421 gaatacaggg tcatcaagcg cccaatatta ccacccgttc cgacggtatt gccacaaatc
    12481 acttggtcaa tgggaactgg atacttattt tgtaaagcgt tgatgagctt tgctccaagg
    12541 atttctggtt gttctttagc aaattgtttc cctactaaac cgataggggt tctaaggcct
    12601 gcagcaatat aaacatccgt cattatattg acctccttta ttttcgatgt ccttaaatgg
    12661 ttattatata attatttctg aaggttttct tttttgaact aataactgct aaaaatacac
    12721 ctaaattaat ttagagaatc tctttagtct cgctagtgtg ccatcaataa aatctataaa
    12781 attctctaac gtcattgaaa tgtcaagtcc cacaactatt gtcgtagaag tcacttactt
    12841 tgttgcttta acattcaaac tgtaaccttt gtttttgata cagggtgact ttattatact
    12901 ggaaaaccat tcctaagaaa agaaaatctt atatagaata aagaattaga caccataaaa
    12961 aagctaagct gtgacactta acttttttat ggtattgaca aaccttgtct ttactattta
    13021 ttgatagtta atgcctctaa ctaaaataaa agccatgtct gtatcagcct gcaaggcatc
    13081 tgctaagctg gtatcgttac tagatttgac aggtctcata aaggcaaaag atctcaaagt
    13141 tccataaacg ttatctagca attgcatgca accacttgaa atatatctgc ttatgttatt
    13201 ttaccgccct taatttagac caatctgctg atgatggttc caaccaatgc ctacacttgg
    13261 taaaccatca caaaaaaaag cagccgtttt tacaacagct gccttccttc attatctaga
    13321 ttttcatatt ctgacctaaa cgattttcaa tttgtttaag agtctctcta ggaacctgca
    13381 ctttcataag catccaggcc ccatttccaa agcttaagcg acaaggccaa aaccagtaac
    13441 gacaccacta ccaagcctcc aatattaaag agcaggtgtt gacctgttaa aaaataagaa
    13501 gcagggtaat aagctgtaaa agcaaaggga atgataaaac tgattaacca ccgcaaaaag
    13561 gaatggtaaa tggacatagg gtacttagaa aagtcattga acatgtaaaa aatatagata
    13621 actgccccag actgcttggt ccaaaaagaa atgctggcgg tcgcaatttt taaagaggtg
    13681 taaatcaagg tcgcaaaagg aataaccaaa ataaacaaaa gcaccttagg aagagtccat
    13741 acgatactac cagccgtggt cactaataag ataaccccaa ccaataattc acccaaggca
    13801 tccacttgaa atgtctcaac caaaacatga aataaaggac taattggtct agtgaggtac
    13861 ttgtcaaatt ctcctttgcg gacaagccgt tgccctaaag cccaaagatt gtcaaaaaag
    13921 aggtgatcaa ttccctttgg aatcaaagaa aagccataaa taaaggcaat ttgttcaaac
    13981 gtccagcctt ctaaagaagg gatatgttgg aaaagtaccg ataaaaagag cagattaagt
    14041 ccctgagtga gaaaaacacc tagcactccc accacaaaat caaccttgta ttccataatt
    14101 tgtttgaggt attgtttgat aaaaatagcg tgcatacgtc tcaattttgc catctcaccc
    14161 tccttgaatc gttaaatggt actgaacctt tttccagatg acttgcgata agactaccat
    14221 caccagtaac caaaagattt gcaaacttag ggccaccatt atctgactaa ggctgtattt
    14281 cccaatgaca atcataactg gcgtgtaaac caaagaggaa aacggtagaa aactaagcac
    14341 tatagaaacc actttaggaa aaaaagccaa tggaatcaaa ctgcctgaca taaaggcaac
    14401 caaggcattt ttcaataaat tagaccccca aaggttttta aagacaaatg ctgaaaagcc
    14461 aaaacaaatg ttgaaataaa aattgattaa aaaagctaat aaaaggctaa ctaaatacag
    14521 acaactgctg gctaggactt gcaagataga cagccccgcc atgactttaa taccagataa
    14581 gaccattaaa aaaggaaagc cgacactcat tagcacaatc cagcgaaaac caatttccat
    14641 aaagaggtaa gaggctgcaa aatgaactgg tcgaagcagg cgcatgatga tagaaccatc
    14701 tttcacttct tcgccaatca taaaggagct gtctgatttg gtcagtaaag tggtcacaaa
    14761 actcatgata atgtaaaagg tcatgtcaga cagagtaaaa ccattgatta aggattgctt
    14821 agacgaatca aaaacagcct tccagaggta ataagccaca aaagccccca tgacatctcc
    14881 aatacgatac aaaaagaaat taacgcgata ggttattaat tcctgaattc ctgcactgag
    14941 aaagggtcta taacgtttcc aaaatgacca catcttaaag ctcctttcgg tagaaacgac
    15001 gaacaatatc ctcaatatca acatcagtca tcttcaaatc cctgaccgca aaatcagcca
    15061 tggttttttg aataatgtcc gctgtttgat agcgcgaact gtcatattga atgtctaaac
    15121 taagctcatg ccgttccact gtgatgtcag gtaagcccat aaactgtgag accacctgct
    15181 cctgccctgg cttcaactca aaagacagac tcttcatttt tccaaagctt tgctttaatt
    15241 gggtcaccgt tccatcaaag atttcttgcc ctttatcaat catgataatc cgatcacaga
    15301 gctgttcaat atcactcaaa tcatgggtcg tcagtaaaat agttgtctct tcttcttgat
    15361 taatttgagt aatggcacgc cgaatgttgt ccttcacaga aacatcaagt ccaatcgttg
    15421 gttcatctaa aaacaatact ttaggattat gcaacaagga agcagcaata tcagctcgca
    15481 tccgctgacc gagtgataag gtccggacag gatccttaat aaactcattc aggtccaaaa
    15541 catcatttaa aaaatccatg cgcttgcgaa aggctttttc aggcacatcg taaatttctt
    15601 ttaacacgac ataggtctct tgcaaggcca aatcccacca tagttgtgtt cgttgaccaa
    15661 aaacagctcc aatgtctctc acataatctt gacgattatc ttgtggaatc tttccgttaa
    15721 tgcgacagta acctgatgta ggctttaaaa tacctgttaa catcttaatc gttgttgatt
    15781 ttcctgcacc attggctcca ataaaaccta aaatttgccc tttgggtacc tcaaaagata
    15841 agtccttaac cgcctcaaag atttctcttt ggggatgaac aaaggacttc aaggctccct
    15901 ttaatcctgg ctctttaatg gttttggaaa aatttttttg aaggtgggac acttctatca
    15961 tgaccattta ccattcctcg tttctgttat cgtcttatca ccgttactaa acaatttatt
    16021 ataacaccat gaaaaagact gtgcaatcgt ttgcttaatt tttaagaaag aaaaagaagc
    16081 ccataaggac ctctttttgc cattgattaa gcttgtgcat ctggacgtga cttgcgagca
    16141 atgtctgcca agatgttttc cacaaattct tccacagatt cagtgtgagt tgccttgcta
    16201 ccatagcggc gaacattgac tgatttgtct tccatttctt tgtccccaac aattaattgg
    16261 taaggaattt tgctggtttg agacgcacga atcttgtatt gcattttttc attgcggtca
    16321 tcgacatctg cacgaacacc acggtcacga agggtttttg ctacttccca agcatagtca
    16381 atgtgggctt catttgaaat tggaatcacg gttacttggt gaggtgccaa ccaagttggg
    16441 aaagcaccct tgtaagtttc aataaggata gcagtgaaac gttccatagt tgagataaca
    16501 ccacggtgaa tcatgactgg gcggtgttct tcgccatctg caccaatgta tttaaggtca
    16561 aagcgttctg gcaacaagaa gtccaactga atggttgata gggtttcttc gttaccaaga
    16621 gctgttttca cctgaatatc aagcttaggc ccataaaagg ctgcttcacc ttctgcttca
    16681 aagtaatcta cacccatctc atcaagtgca gctttaagca tactttgagc attttcccac
    16741 atctcatcat tgtcataata tttatgagta tcgttagggt ctcgatatga caaacgaaaa
    16801 cgataatcag tcaagttgaa gtcagcataa acatcaatga ttaattgaag ggctcgttga
    16861 aattcttcct ggatttgctc tggtgttacg aaaatgtggc catcattcaa ggtcatttca
    16921 cgtacccgtt gaagtcctga tagggcacct gatttttcgt aacggtgcat catgccaagc
    16981 tcggcaatac gaataggcaa ttcacgataa gaacgcacat gatttttata cacttgaatg
    17041 tggtgtgggc agttcattgg acgaagaaca aactcctcac catctcccat atccattaca
    17101 gggaacatat cttcttgata atgatcccaa tgacctgatg tcttgtacaa ttctacagaa
    17161 gcaagtggtg gtgtgtaaac gtgttggtag cctgatgcta attctttatc tgtgatgtag
    17221 cgctcaagtg tacgacgaat agtcgctcca tctggtaacc aaaatggcaa gccttgacca
    17281 acttcttgac taatcatgaa caagtcaagc tctttaccaa gcttacggtg atcacgttct
    17341 ttggcttctt ctagacgagt caagtaagct ttgaggtctt ttttatcaaa ccaagctgtt
    17401 ccatagatac gttgcatcat gttattgtcg ctgttaccac gccagtaagc acccgccaca
    17461 tttagcaagt ggaagacttg gatacggcct gttgatggca catgagggcc acggcaaaga
    17521 tccacaaatt caccttgacg gtaaaccgtc aagccagcac cagcatgctc attaatcaat
    17581 tctaccttgt aaggatcatc tttgaacaat tccaaagctt cttctttggt cacttcttca
    17641 cggatacatg ggtaattttc tgtcacgatt ttttgcattt cagcttcgat acgtggcaaa
    17701 tcttcgtttg aaatttggcc ttctgcatta tctgtatcat agtaaaagcc ttctgcaatg
    17761 gcagggccca ctcccaaatg aagatttggg aacaagcgtt ttgcagcttg ggcaaataaa
    17821 tgggctgcag agtgacgaag cacctcataa gcatctttgt gatcaggtgt cacgatttca
    17881 atactgccat cttcttcaat ggcacgagtg gtgtcaatga gttgatcatt gaacttacca
    17941 gctaaagctt ttttagccaa tgatttgctg atggactcag caatgtcaaa cgttgttacg
    18001 ccagattcaa attcacgcac ggcgccatct ggaaaagtaa tcttaatcat ttgctttctc
    18061 ctttaagtca gttaagattt ccactaaaac atggatagta agacaaatta gggacaagag
    18121 gttagtgaat agctcaacac caccacgtag aagaacaata ccttattcac gaatctaccc
    18181 tccctagtcc ttaaaaacaa ggctaatccc ctccaaaaca aaaaaactga ccgcatccca
    18241 aaggacgcaa tcagcgtggt tccaccttaa tttatgcagg acaaaaaaca tgccttgcac
    18301 ctctagtggc gataaggggg ccaccctttt atgtttgcat aaaaaccagg aaggagtatc
    18361 agattagcta tccttgtgct ctttccacca accagcactc gcttaaaaga ttctgtccaa
    18421 tctaacttgt cttcaagata attatagcaa gttttcaaaa atttacaagc cttaatccag
    18481 aaaatctttg atagcatgga ccagcttgat aggagccttg actactttta ctgaggtgat
    18541 agctgtgacc ttagcagcac gtttaggcaa gtgaatagca ccttgcacta attttagaga
    18601 actactttta ccagaatgat taagataaag actcaacttt tgagcttctt tgctatttct
    18661 agcaattaac gtatctaaat agaacgtgta aatagatttt ccaaagtgct gtgctgagat
    18721 ttcataacgt ttttttgcta ataaccgttt atccataact ggtgttttta gtatggcatc
    18781 aataatagca tcagttaaat ctgtttcagc gtaataaaga gtgccaaaca ttttatcagt
    18841 caccacatca tctaaataag gattgccatg agcaataata ggagtgccac tagccaaact
    18901 ttcaatatag gtcaagccct gagtctcact ggtcgatgct gagataaaga aatcacaagc
    18961 cttatagtac agagcaacct tatcatgagg caccatgcct gtaaaggtca cgtgtttgtc
    19021 aacctctaac tgcatcgcca agtgtttcaa atcttgcaaa taggggccat ctcctacaat
    19081 aataagcttt atcttggcat tttcagccaa aatagctggc atctgattga tgatagcttg
    19141 aatatttttt tcataagaaa tccgtgacaa actcaataac atggtttcat caccagcaat
    19201 gcccaattct gcttttaagt tggttacttc ttctgctgtg atgtcatcac gaatatattt
    19261 ttccaaagga atgcctgttg ggataacccg cttagggata gtcacttcgt aaccttctag
    19321 aagattgagg acaatcctac ttgggcagat aaccccatcc aaatccttca aatagcccct
    19381 aagaagaggt ttgaccatac ttggtcgaat gatttttccg ttggcaatat aactcacgta
    19441 gtcctcatat tgggtatggt aagtatggac aacaggaatt cgcaaagctt tgcctatcat
    19501 tttccctaat aaacctaagc taaactcagt ttgcgtatga ataatatcaa gattatagtg
    19561 ttttgcaatt ttgtatgacg aaatgaggcc acgataaacc acacgtctat ccgtaaatga
    19621 cacaaaagga acacttggca gtcgaataat ggtcgggtct tcaaagcgtt tgacatctct
    19681 atcagtagtg gtgaaaatat aaacttcgtg accttctttt tctagctctt cttttaacgt
    19741 acgaatacta gtagcgactc ctgaaacttg tggaaaatag gtatctgtga atagacctac
    19801 acgcatctta taactccatt acttttttat agacatctac taaggcatgg ccaaccgttt
    19861 ctaggcgacg actctgggca accttgtaac cagcttcaac tttgttgctg gcaccagaaa
    19921 agactttttt cagagcttct ataaaacctg gtatatcggt tgctaattcc gcactacttt
    19981 gatcaaccca tccgtagtaa actggtatat cacgtaaaac aaggtgctgg cgactggcca
    20041 aggcttctaa gacaacaatg ccttctgttt cttcacgact tggaaagaaa aaggcatctg
    20101 caccagtcat ggcaccttca taaacatccc ctttaatgta tcctgggaaa ataagatttt
    20161 tcgggtggtt accattgacc atttggcgaa cttgagcagg aatgacccat ttgttggtct
    20221 cgccaaacca gataaaacga acatctggca tagcttgggc aactttgaca aagtcatcaa
    20281 ttcctttcct cagaaaaaat aatcctgctc ccataaccac tttttcaccc tctttaatgt
    20341 caaagtagcg acgaaaagct gcttcctttt taggatctgc tccgtactgc tccaaatcaa
    20401 tcccatttga cactgcaaaa ataggtgact tcactccata actctcaatc aaagacttag
    20461 aatatagggt aggggtaatg atagcatctg ccttattgta aaagtgacaa aggtattttt
    20521 taaaccaagg agataataga tttgaaaaaa taaaagaatt tctaaaatct tcttctgtag
    20581 aatgcccatg catgataacc ttcttaccag ctttttgtgc ttttatcatc agcagccaac
    20641 tttttaaacc ataggtattg agatgaacca aatcataagt ttctcttgga ttagtcgtaa
    20701 aatgttgacc aacaagtgac aaggctttag cctgatgctt aatcgctcga ccaattcctg
    20761 attttcttag ataattttct gcttctaaat acaataagac tttcataagt tctattatag
    20821 ctcattttat agtatttttc actaagacat gcaaaaatca gccttagggc tgattttagt
    20881 attgaagaaa cagtctattg tgatactttt tgttagatgg tgctcataag tcacagttac
    20941 ttagttgtcc cacgtttttt aataccatga ttcaaaagaa tttctttttc ttccaactct
    21001 tctttgttca tgattttagt caacatccgc atgctaacag cacctaagtc ataaacaggt
    21061 tgactgatag aactcaaatt gggacgagtg tattgaacca ctggtgaatc gttgctagtg
    21121 atgatttcaa agtcctctgg tacgcgttta cctgcttcaa acaagccgtt taaaaggcct
    21181 gctgccaatt catcttcagc cacataagcc gctgttgctc ctgagttaat gacgcgctgc
    21241 gccaattcaa atccttcttt ataagaatag ttcgcttcaa aaacaagacc ttctttgaag
    21301 tcaagcttat tgtgcttcaa cccttctttg taccctgcta agcgcacttt accattgata
    21361 tcatcaatga gtggtcctga cacaaaagcg atacacttat gattttcagc taaaatatca
    21421 acaacgtttg acaccgcagc tctatagtca atgttgacgc ttggtaattg atgatcaaga
    21481 tctacagttc ctgccaaaac aactggagta cgagagcgtg aaaattcggc ccggattttt
    21541 tctgtcaagt gatgccccat aaaaataata ccatccactt gcttggcaaa aagggtattg
    21601 acaacattaa cctccttgtc atcatcttca tcactggagg caagcacaat attatatttg
    21661 tacatagcgg cgatatcgtc aataccctta gctaagatag aaaaataact atttgcaata
    21721 tttggaatca caacgccaac ggttgttgtc tttttgctgg cgagaccacg cgcgacagca
    21781 ttgggacgat agtcaaggcg atcaataact tctaaaactt tcttacgtgt attttcctta
    21841 acatttttat tgccattaac aacacgacta acggttgcca ttgaaacacc agcttcacgg
    21901 gcaacatcat aaattgtaat ggtatcatct gtattcattt tttatcttcc tttctatttg
    21961 aaaatgacgc tttcaaaaag tattttagca tgatttgtaa ccactttcaa gtgttatagg
    22021 ttaatttttg aaaaagtttt caaaaattaa ctcgaagctt gattttttaa gctttttttg
    22081 aaaaaatagt aagtagaaag aaggttagcc tatgacaaaa ttagaccaaa tacgtttgta
    22141 tcttgaccaa aagggagctg aattggcgat tttctcagat cctgttacga ttaactattt
    22201 aactggattc ttctgtgacc cacatgaaag acaactgttc ttgtttgtct accatgattt
    22261 agctcctgtg ctttttgtac ctgcccttga ggtggccaga gctagccagg ccatatcatt
    22321 tcctgtgttt ggttatgttg attctgaaaa tccttgggaa aagatcaagg ccgttttacc
    22381 aaatacagca gccaaaacca tttatgctga atttgaccac cttaacgtca ataagttcca
    22441 tggcttgcag actatctttt cagggcaatt taacaatcta accccttatg tccaaggcat
    22501 gcgcctcatc aaatcagctg atgaaatcaa taaaatgatg attgccgggc agttcgctga
    22561 taaggctgtt caagttggtt ttgacaatat ttccttagat gctaccgaaa cagacgtcat
    22621 cgctcaaatt gagtttgaaa tgaaaaaaca aggcattcat aaaatgagct ttgacactat
    22681 ggtcttaact ggaaataatg cagccaatcc ccatggcatt cctggaacaa ataatattga
    22741 aaacaatgcc ctacttcttt ttgacttagg tgttgagacc ttaggctaca ccagtgatat
    22801 gaccagaact gtggctgttg gtcagccaga ccaatttaaa atcgatatct acaatctctg
    22861 cctagaggca caactagcgg ctattgactt tatcaaacca ggtgtaacag ctgctcaagt
    22921 agatgctgct gctcgtcaag tgattgaaaa ggctggatat ggtgagtact tcaaccaccg
    22981 cttgggacat ggtatcggca tggatgtcca cgaatttccc tccattatgg ctggcaatga
    23041 cttggtcctt gaagaaggta tgtgcttctc tgttgaacct ggtatttaca ttccaggaaa
    23101 ggtcggtgtg cgcatcgaag actgtggcca tgtcactaaa aatggctttg aagtctttac
    23161 ccatactcca aaagagttgc tttattttga aggctaagcc cctaccatct ggttaaacaa
    23221 accctcgcga aaggaaggta ttcgtatgga tcaaaccatt catcatcaaa tacagcaagc
    23281 actacacttt agaacagccg ttcgtgttta taaggaagaa aagatttctg atgaggattt
    23341 agcccttatc cttgatgctg cttggttaag cccttcttct gttggcttag aaggctggcg
    23401 ctttgtcgtt ttagacaaca agcctattaa agaagaaatc aagccctttg cctggggggc
    23461 ccagtatcaa ctagagacag ctagtcactt tattctttta atagctgaaa aacatgcaag
    23521 atacgatagc cctgctatca aaaatagcct tttacgacgt ggtatcaaag aagatgatgg
    23581 tctcaacagc cgcctaaaac tctatgaatc tttccaaaaa gaggacatgg atatggcaga
    23641 taatcctcgg gcactctttg attggacagc taaacaaacc tatatcgctc ttggtaatat
    23701 gatgatgaca gctgctcttt tgggcattga tacttgccct attgaaggct ttcattatga
    23761 taaggtcaat catatcctag ctaagcataa tgtgattgat ttagaaaaag aaggcattgc
    23821 tagcatgtta tccctaggct atcgcctgcg agatcccaaa catgctcaag ttcgtaagcc
    23881 taaagaagaa gtgatttcag tcgttaaata aggagattaa aatgaaagca ttacatacct
    23941 gtatccgcgt caaagacctt gaccagtcgg tagcttttta cacaagcgcc ttccctttta
    24001 aggaaaacta tcgtaaagat tttccagata gtcaatttac tcttgtttat ctggctttag
    24061 aaggagaaag ttatgaatta gaattaacct acaattatgg tcatggcgac tacgacttag
    24121 gaaatggcta tggtcatatt gcccttggct ctgaacattt tgaagcagac cataaaaaac
    24181 atcgacaagc aggttttcca gttaccgata tcaaagaact ggctgacaaa tctgcccgct
    24241 attatttcat tcaggatcca gatggctaca aaattgaagt cattgattta aacaactaat
    24301 actattaaca acagaagctt taaagcttct gttgttttat tttttaacct gacgattggg
    24361 acaatctcat tattaacaga gttttgaaat atctcagctt ttgtgttaca attgccctaa
    24421 aattccattt gaaagaaaag tctatgacac tactatctat cattgtcccc tgctttaatg
    24481 aagaagcaaa cattctccct tattttgaag aaatgcatca actagaaacg tccatgacca
    24541 accaacttgc ttttgaatac atttttattg atgatggttc taaggataac accttgggta
    24601 ttttgcgtga gctagctgct cgctttccaa atgtgcatta tctgtctttt tcacgccatt
    24661 ttggcaagga agctgggctc ttagctggac taaaagaagc caaaggcaat tacattactg
    24721 tgatggatgt ggatctgcaa gatccacccg aacttttgcc aattatgtac gctaagctaa
    24781 aagaaggtta tgacatcgtt ggcaccaggc gccaaaatag acaaggagaa ccactaattc
    24841 gttcaatgtg ttcgaatcta ttttatggac tgatcaaaca cttatcagat actgaaatgg
    24901 tcaatggagt tcgggattat cggttaatga ccagacaagt cgttgatagc attcttgagt
    24961 tgggagaggt taatcgtttt tcaaaaggga tcttttcgtg ggttggttat cgtatcacct
    25021 atcttagttt tgaaaaccaa aaacgcaaat atggaaaaag tcgttggcat ttttgggagt
    25081 tgctccgata ttctttagat ggctttatca acttttcaga aatgccgtta accattgcta
    25141 cctggacagg gactttcagc tttttgattt ctattttcgc catcttattt atcattatca
    25201 gaaagatact ctttggtgat cctgtctctg gttgggctag cactgtctct attattttat
    25261 tcatgggagg cattcagctc ttttgcatgg gtattattgg aaaatatatt tcaaaaatat
    25321 tccttgaaac taaaaaaagg cctctctata ttatcaaaga aaaacattaa attaaaacat
    25381 ttttctcatc aatcgtttcc tactccttct gtgcgcgaag ctttcttttt aagcccgtta
    25441 taccaaatga taatgacctt tccaaaatag tatcaccttc cttaacactt taagtagaaa
    25501 aggaactatt aggttgagcc tttttgcaaa tcctagcgac taatgttata atcgtcatac
    25561 tattgaaaaa ggagttcttt atggagtgga ttaaattaat cggtattgtg attatcgtat
    25621 tagggtttat tttaaaatgt gatgctatcg ctaccgtagt tgttgcagga cttgttaccg
    25681 cgctggtttc aggaatttcg tttattgatt ttctagatat tttaggaaaa gaatttacca
    25741 atcaacgttt gctaaccatt ttcttcatca ctttaccgct tatcggcttg tcagaaactt
    25801 atggactgaa acaccgagct actcagttga ttcaacgtgt tcaagccctt accgtcggcc
    25861 gtttattgac tctctacctt attattcgag aattagcagg tctcttttcg attcgactag
    25921 ggggacatcc acagttcgtt cgccccttga ttcaacctat gggagaagct gctgctaaag
    25981 ccaacattgg agaagagttg accgatgcag aaaaagatga catcaaagct atggcagctg
    26041 ccaatgaaaa ctttggcaat ttctttgccc aaaatacctt tgttggcgca ggaggtgtcc
    26101 tacttatcgc tggaacttta gaacagcttg gctatggtgg taaccaagct aaaattgcat
    26161 tttcttctat tttaattgct attatctcta ttattatagt tgctatttac aattacctct
    26221 ttgagaaaaa aatggaacgt caacatcaga aaggagataa ctaatggcta acattgcaaa
    26281 ccttgtttta gaaacgatat atatccttat cggcttgcaa ctgtttcaca cagcctactg
    26341 cacctttaaa gataaaacca accctgtcta ttttgggaca gctctgttct ggggattgct
    26401 gggtgttacc ttcgttggcg gtgccttttt gcctaacaaa gttatcggtt ttatcgtgat
    26461 tgtcctagct cttttaacct tgtttaagca agttcgtatt ggaacattac cagcctttaa
    26521 tgaacaaaaa gctgaagaaa gtgctcaccg cattggtaac tggattttct taccagttat
    26581 gttaatggct atgatttctc tacttcttgc cttgatcctt cctgatttca gtaaaagtgc
    26641 cattgggatt gctggtatct tagccactat tgctatttta ataatcacta agcaaaaacc
    26701 atctgctctt ttagctgaaa ataatcggat gaaccaacaa gtgtccacaa gcggtatttt
    26761 gccacagctc ttaggagctt taggagctat ttttgcagct gctggtgttg gtgatgtgat
    26821 tgcttctctc attcgggaga ttgtacctgc tgatagccgc ttctttggtg ttctcgctta
    26881 tgtgcttggc atggttattt ttactatgat tatgggaaac gcttttgctg cctttaccgt
    26941 tattacaacc ggtatcggtg ttccttttgt ttttgcttta ggagctgacc ctattattgc
    27001 cggtgcttta gctatgactg ctggtttttg tggtacctta ttaacaccaa tggcagcaaa
    27061 ctttaatgcc ttgcctgttg ctttgatgga gatcaaagat cgaaatgcag ttatcaaaaa
    27121 gcaagctcct atcgcccttg ttttaattat tagtcacatt gccttaatgt atttacttgc
    27181 ttattattaa cttttttgct aagttagtag cgtcagttat tcattgaaag gacattatta
    27241 tgaaaattct tgtaacaggc tttgatccct ttggcggcga agctattaat cctgcccttg
    27301 aagctatcaa gaaattgcca gcaaccattc atggagcaga aatcaaatgt attgaagttc
    27361 caacagtttt tcaaaaatct gccgatgtgc tccagcagca tatcgaaagc tttcaacctg
    27421 atgcagtcct ttgtattggg caagctggtg gccggactgg actaacgcca gaacgcattg
    27481 ccattaatca agacgatgct cgcattcctg ataacgaagg gaatcagcct attgatacac
    27541 ctattcgtgc agatggtaaa gcagcttatt tttcaacctt gccaatcaaa gcgatggttg
    27601 ctgccattca tcaggctggg cttcctgctt ctgtttctaa tacagctggt acctttgttt
    27661 gcaatcattt gatgtatcaa gccctttact tagtggataa atattgtcca aatgccaaag
    27721 ctgggtttat gcatattccc tttatgatgg aacaggttgt tgataaacct aatacagctg
    27781 ccatgaacct cgatgatatt acaagaggaa ttgaggctgc tatttttgcc attgtcgatt
    27841 tcaaagatcg ttccgattta aaacgtgtag ggggcgctac tcactgactg tgacgctaat
    27901 aaacctattt taaaaaaaac agagatatga actaactctg ttttttttgt gctaaaaatg
    27961 aaagacctag ggaaactttt cataggtctt tctcaattgt catcttaatc taatactact
    28021 tctaacatca gcgggtatag tttgccagta attaagaaac gttgttgatc taaatgagca
    28081 atcccattca aaacattaag gtcagggtaa tgggacttat caagatttaa ggcttttaac
    28141 aaaggactaa tatcataggt ggctaccacc tttccagaat caggttggag tttgacaata
    28201 gtattggttt gccaaatatt ggcatagaga taaccatcta catactctaa ttcgttaagc
    28261 attgagatgg ggacactttc tatagcaact agtacggtat ccaataaagc aaaatctttg
    28321 gggtctcgct tttgcaaaaa agcatttcca ctagtcatcc aaagacactg gttttcctta
    28381 tcataggcta atccccagcc atctccttca aatggatagg cccctaaaca attgcaggta
    28441 gccttatcaa acttgtaggc tacaccctct ttataggtta ataaccaaaa ataatcctca
    28501 acaactgtta gcccttctgc aaaaactgta tctggaaaag ctattttttc tgaaaagatc
    28561 tcttgagtaa ggtcatacac ccctactttt gagaaaccat aacgaccggc actaagtaat
    28621 atatgattgt tgttgagttg ttctaatccc tgcgtgtata agttgctatc ataagaataa
    28681 gttcgtaaca aacgaacttg tcctttagtt atcataatac tcattcacct taccttgcat
    28741 tgtagtgttt catttgtttt ttaatatcac tttcctgatc acggcgttta atggtttcgc
    28801 gtttgtcata ctcgtgtttc cctttagcta gaccaatcag aactttagca aagccatcct
    28861 tgaggtaaac tttgagagga accaaagtca tgccagatcc tttaagttca tttgctagat
    28921 gcgtaatctc acgttttttg agcagcagtt tgcgggttcg ttcaggatca gcgttccaaa
    28981 tattaccttg ttcaaaaggt gcaatatgca cgttgaccaa ccacgcttcc ccattcttaa
    29041 tttgggcaaa gccatctttc agttgaatac gggctgcacg aacactttta atctcagttc
    29101 ccgttaagac aatccctgct tcaacggttt caacaatgtg ataatcatgt ctagcctttt
    29161 tattttgcgc cagtatatga ccttcccctt ttgccatagt taactccttt tacgactctt
    29221 cttttttgct tgttctttgt aaaatggttt tttagaccct tttttagttt tacccttggt
    29281 ttttgccttg gctacttctt taggttcttt tttctttatc cctttagatg attttgagga
    29341 tttacggcga tctcgtcgac tagctttatc cgacatcttg attttttcaa ccacatcaaa
    29401 atcgctaggt aaatactcaa agtcaatgtc accagtttcc ttgtcagcct taaccaattt
    29461 cacacgaata ggttgaccaa ctttaaagac tttacctgat ttttcacctt gaaggcttag
    29521 cgttctctcg ttaaagtgat agtattccgg taagctagtg atatgaacca aaccttcaat
    29581 cgtatttggc aattctacaa aaaaaccaaa tttaacgaca ctggccacga taccgtcaaa
    29641 ttcttcgccg acatactctg ccatatactc agcttttttc atagcttcaa ccacgcgttc
    29701 agcatcaata gcacgacgct ctaactgtga agaagatgtt gccagctctg gaatgatctg
    29761 agcaaaatgg tcgcgctttt cttgactagg ttgattgtac tcacgaacca tgcggtgaac
    29821 caacaagtca gggtaacgac gaatcggact ggtaaagtga gtgtaatatt ctgcggccaa
    29881 accgtaatgc ccatgattat gttcagaata tcttgcttgt tgcatggaac gtagaagcat
    29941 catgttgagc acttctgctc ctggttgacc ttcgactttt gccataaagg cttgcaaggc
    30001 ttcctgagaa atcttgttgg ctgttccttg aatgtgaata ccaaaggtgc tagcgtagtc
    30061 aataaattgt tgaagttttt caacctttgg ttcttcgtga atacggtaga taaacggtaa
    30121 cttagctttt gcaaaatgtt ctgccacaca ctcattggct gctagcataa aggattcaat
    30181 catccgctct gcaattcccc tttgacgaag caccacatca accggcattc ctttgtcatt
    30241 aacaataact ttagcttctt gcgtatcaaa attcaaggcg cctcgttttg accgcatagc
    30301 ttccaaaatc ctatgcaaag ccaccatgag ggtcacatca tcagcaatgc tagcgaattc
    30361 ttggagcgct tcttcatctc ctgcaatcat gtcattgacc gtactatacg tcattctgta
    30421 agttgtctta atcactgatt gacagatttg ataattgacc acatgcccct gcgggttaat
    30481 ttccattaag gctgactggg tcaaacgatc aacgttagga ttcaaagagc agatgccatt
    30541 tgacaaacgc tctggtaaca tcggaaccac acgatcggtg acatagacag aagtgccacg
    30601 ggcgatagct tccttatcaa gggcagatcc ttctgtcaca taatatgaga catccgcaat
    30661 atgtacccca agttcatagt taccgttatc caatagctta atatggatag catcatctaa
    30721 gtctttggcg tccgcaccat caatagtaat ggtcgtttct tgacgcaaat ccacacggcc
    30781 tattaaatct ttagcagttg gtgcttctga aatagcattg gcctcggcta aaacttctgc
    30841 tgggaactct gacacgatat ccatcgattc aaggacttct aggacatcaa ttccaacgtc
    30901 tccttgatgg cctacgatat cacgcacact ggctacaaaa taatcgtgcc cgcgtgtcgg
    30961 gtatttatca atatcaacct tgatgatttc agtgccttta agcacaacag gttctttttt
    31021 gatatagatt ttttgttgaa tcttttggtt tttggacctg atataaccag catattttgg
    31081 tttgtcatca tctaaaataa aggttccaac agctgttttt aaagaacggt caacaatagc
    31141 aacgacctta gcttcagccg ctgtgccttt gagacggtct gctggctttt taaccactac
    31201 ttcgacagta tcaccatcaa tagcataccc aacaccatta cgaccgataa acatatcgtc
    31261 ttcattctca tccacatgta agaaaccaaa gcctgcttta ttggcacgaa aaacaccctg
    31321 aacagtaggt tcttttttct tttcacgctc ttttctaaga gccagactgc catcatctga
    31381 aaaccgtaac aggctctgac tttccatttt ggaaatggtt ttaataaggc tgggaaaatg
    31441 cttagctcca gccatctcca aggccgcagc caagtcgttc acattggact tgccatgctc
    31501 cttgaggtaa gtcataattc tttctttcat catacctaat ttctatttct gttttgtttg
    31561 ttggaggata tcaatccgtt tcgctgataa aaaaatgagc tagactaact ctgtcaagct
    31621 cactccttat ttacttgata aaatggcaag cacaagtgca atcgctagcc aaaaaaatac
    31681 tagaactgct gtgaatcgtt gcatgaatgc ttcaaagcca cgagcttttg tacgttcaaa
    31741 caaggcttct gaaccgctgc tatcaaaaac attgctactt gggttttttt gaggttgcat
    31801 aaaaatagca atcacaagca ataccgacag tactagcaat atcgtaagta gtaagttgta
    31861 catgttattt cctccactat tgtcatgacc attctaacac aattcttatc aagtttcaac
    31921 atgcagggtt acttttctct ccttggggca gtatttggga acttttattt tttccggatg
    31981 actgctttta tttttactgg ttagataatt gttactgcca cactcactgc attctaaatt
    32041 aatttttact ctcacacaat atccttaact ttaatatatt ttcgaaatat aatcaaactc
    32101 catattaaat taacaaacac aatcaaacta gtcacataaa aaacagaacg gtagcctagc
    32161 actacagcca catttgatcc gataaaaggg ccaatgactt gaccaaggtt actaaacatt
    32221 tgattatagg caaatactct agaaatacct tcttttggtg ttaacttagt tagtaaagag
    32281 ttaatacttg gcatcaaagc gcccacacca aacccataag caaagcgtag tactcctaat
    32341 tgaaaactgg tctgcgctaa ggcactgcta aaatacatga taaagctata acacaaagcg
    32401 gctaacaata accgatgatt gccaaaacga tctcctaatt ttcctaagta agaactgcta
    32461 aataagctag aaaaccccat ggccgaaact accaggcctg aagtaaacat taagttgtga
    32521 gtttgaccaa gatgacgaat atacaatgat aaaatggggg ccactgattg agctgaaatt
    32581 tgaataatca tactagtcac aaacaaacca agcataatct ggggactttt tacctgtttt
    32641 aaaatgactt ttgtaggtat catctcaaag cgcctaatcg gcttaaactc ttctttaaca
    32701 taaacagctg tcattaaaga acataaaaat aatatcacac caactaataa gaaaacttgt
    32761 cgaattccta atagctctgc caaaatcccc cctagtaaag gaccaattaa agcgcctgct
    32821 gtcactcctg ttgctaatgt gcctaaagca taacctgact cctcttttgg ggcttggctg
    32881 gcaatcaagg cagtggcatt tggcacatag cccgcaaaga cacctgttaa taatctcaaa
    32941 atgagtaacc aaaacacatt aggaataata gctaaaccac ccatggtaaa ggtcatgaca
    33001 aaactggctc gcagcatcat aggttttcgg ccataacgat cagccaactt cccccaaaca
    33061 ggagcaaata aagctgaagc aagtgccgtc acagcaaccg ccagaccagc atagtattct
    33121 actaattctg tcggagtacc taaattttcc acatatagag ccataaaagg cataacaagt
    33181 gaaaagcttg ccccagtaaa gaagttacca agccaagcca cttttagatt ttgtcgccag
    33241 ttcactgtcg ttaccgcttt atcactaata gatcatcatc ttctttccat tgggcctttg
    33301 attattataa cacatttctg ccaaaaacag tgtcccataa tagtgctaag tctcatctga
    33361 tagccttcat cgtttacgta aactacccag taaacctctg accagttctc gcccaattgt
    33421 tctaaccgtc gtactaataa acgcatctgt tgctttttcg acgactgttt ttcgtggacg
    33481 cccaacagaa cgccgattag cttttttggt agctgcttgc gccttgatgg cttctttagc
    33541 ttctttttcg cgttgtgctg tcgctatcgc ttcttgggcc agtcggttgt cttctaaaac
    33601 cttagcagct aatttttcat aagcagattc acggtcaatg gactgactat atttactggc
    33661 aaaaggtgag gactgcacaa gctgctgact ctctatctct gacaaaacag caaagctact
    33721 cttaggcggc atgatatagg cacgttcaac gatggatggt tgtcccttat cattcaaaac
    33781 agaaatcaag gcctcaccga cttctagttc tgtaatcacc cttgccacat ctaagtcagg
    33841 attttgtcgg aaagtatccg cagcgacacg aaccgccttt tgttctttcg gtgtataagc
    33901 gcgcaaggca tgctgaatac gatttccaag ctgagccaaa accgtttctg gcaaatcaag
    33961 tgggctttga gtcacaaaga aaatcccaac tccctttgaa cgaataagtc gcacaatctg
    34021 ttcaactttt tccaagaaaa ctttaggggc atctttgaag agcaagtgag cttcatcaaa
    34081 aaagaaaacc atcttaggtt tgtccaaatc cccaacttct ggcaataatt cgtacaactc
    34141 agacaagagc caaagtaaga aggttgtgta aagggtagga gattgaaaaa gcttagtcgc
    34201 tgacaaaatg ttaatggctc catagcccga agcaacatct aattgcatca aatcagccac
    34261 atctaaagca ggctctccaa aaaattggtg ggctccttct tgttctaatg tcaagagact
    34321 tctttggata gccccgatag attgcttggc gatattaccg taatggctgg agtagtctga
    34381 ggcatggtca ccaacttctt ttaagatagc ctgcaagtct ttcaaatcaa tcaaaagcca
    34441 gcctttctcg tcggcgattt taaagacgat gtttaagaca cctgtctggg tatcattaag
    34501 attcaataaa cgcgacaaca tcatcggtcc catttcagaa atcgttgtcc gtaagggttg
    34561 accgttttga ccaaaaacat cccacattct tacaggaaag gcctgaggct ggtaatcact
    34621 taccccgatt gtggctagac gcgcagccaa tttatcagtc acctctcctg ctttagtaag
    34681 attagacagg tctcctttga tatctgccaa aaagactggc acaccagcta aacttaattg
    34741 ctctgctagc acttttaagg tcacagtttt acctgttcca gtcgctccag caatcaaacc
    34801 gtgacgattt agcatcccta attgtaaggc tatcggttga ttgccttttg caattgtcat
    34861 tgtagtcata ggcttcctct tttttgatga tcatacttgt cgatatgtgt ttacccataa
    34921 gttaaagtgt ttagaagggt ctcgctctta atactattat aacatataac ccttgatgcg
    34981 ctaatttaaa agggaccagc tagttttaga cagaaatagc ttgattttga cagctatgat
    35041 acgaatctct cagcttagct acctcggatt ggctaatgac aacaacgcag attgtacttg
    35101 ctttattaac gtttccatgt ctccattatt atcaatcact agactggcat agggcttttt
    35161 ttcctctatt ggtaactgac tggctattcg ctgccttgct tttcctttgt ctaaacgatt
    35221 tctagccatt aagcgctgca attgtgtctg agcatctaca taaaccagcc aaatcgcatc
    35281 aaaccagtct tggtagccca attccattaa aaggggaata tccatgaaaa aaatggcttg
    35341 gctctgtgct aagtggtcac gcttagccgc caattcttcc ttaatgattt gattttgaat
    35401 ggctgaggat gttgccatat tatctgggtt tgaaaaaagc atttctgaca gctttgtgcg
    35461 atctaactca ccatctgctt ttaaaatctg attcccaaaa gcttctctaa gagcctcgta
    35521 aaggcgaccg cctttttctt gcaagtcatg gaccacttga tccgcatcaa tcacctgata
    35581 accagctttt ctaatgacct taaccacagt cgattttcct gatgcaatgc ctcctgtgat
    35641 gccaataatc atggtctttt tttctggcat tttggacaaa tgtgcgtccc ccttcctcca
    35701 acttttaatt tgacaatagc ctgtccacaa cgaggacacg gtttcccagt ttgaccataa
    35761 acctgcaaat agtcctgcat ggtgccatca gctcccaaag cattacggta agtacggacg
    35821 gtcgaaccgc ccttttcaat tcctaaagct aggattcgta tggtttcatc atgcagccgt
    35881 tttatctccg ccttattcaa cctagaagac gcagtttctg gatgaacctt agcagcccaa
    35941 agtacctcgt ccacataaat attccctaaa ccagcaacca aggtctggtc taacagatgt
    36001 ggttttatgg gtttttggga ggatagcaga gcagcctcaa aggtttttaa cttaaaggtc
    36061 tctttctttg gttcagggcc tagttttcgt ttggcaaaaa acgctgataa ttgagatttt
    36121 gttatcaaat caaaggttcc aaatttacgc acatcttggt aaaccaaggt cgaaccattt
    36181 ttcaattcaa aaaagacatg aaagtgtttg ttatcaggga cctcatctgg aaaaagcaaa
    36241 tatttgcctt ccatccgcaa atgtgatacc aacactaatt gccccaaatc aattaataaa
    36301 tattttcccc gacggccaac tgactgaatg atttgaccag gtagggtcag ggcaaacgtc
    36361 tctaagtcgg ttttaaccat ttttggcact ttaagcgtaa cagccacaat ttcttggcca
    36421 agcactaaag tctcaagccc tcgtcggacc gtttcaactt ctggtaattc tggcataatc
    36481 cgttatttaa aggacagcta gaccctttgc tgctacaaag aataaactca gcataaaaaa
    36541 gtcactcaat agactcaggt ctaggatact gactgcgttt caaaaaacac agctgtcctt
    36601 ctcctttctt atttcttatt ttacgaacac atctgataga aagcaactca taaatctgcc
    36661 tcagaccagt cctcatcccc cttacctccc agcactattt ggcggtaatg ttccttataa
    36721 ctataataca atgagtcctc tccaagatac ttaaaaatct gcaaggcctg ccgcatgtcc
    36781 tcttctccag acatttcttc ctgctttaat ttataatacc catgcacata taagaaaaca
    36841 gtcttttcat aaaaattgag ctcgtctcgc agcaaaagat caattttgtt aatcaaatag
    36901 cgactatgtt caaagcaaga atggtcaata ctgataatga gacaattaat ggataactga
    36961 gtcactaaca ttttattggt tttattttgt tccgaataag caaaagatgc taccatttcc
    37021 ttagtcaata aaaatagggt attgtaattc atgaagcgcg agcaattccc cagaagaatg
    37081 atttcataat atccccactg ttccacttta aataaataat ctgtgaggcg agtcaattct
    37141 tcttgactag gtgcaattga ggagtcaata gaaaaaagaa tagctttaat catcgttcgt
    37201 tcataatctt tatgggcata atccttcaac agtttggtca atttaaccac gtttttctca
    37261 gcataacatt ttctcgcctg acttaagagc gtgaaaaaat gcgtatgcgt cttggaatga
    37321 gccgaaacaa attcgtcaat cgtaatattc agtttatcca aaagattaag caagcgactg
    37381 caggtgattt ctgattcccc tcgttcaaat cttgaaattt gtgacttgga caggtattca
    37441 tctgctaaaa aagaaatgct aacctgctta cccttacgta atcgccttaa ggtttttccg
    37501 agttcttttt ccatttttcc cactttcaca acaaaaaatt aaaatctgct aaatccatta
    37561 tataatacaa gtacaaaata gaaaatcaga aaggagacag tcatgaaaaa agttaataaa
    37621 gctttgcttt ttacattgat catggatatc ctgattatcg ttggtggata acctttcgct
    37681 taaaaacaat ccacttttgg gaaaccctta tatttagttt gtaacaggaa aactaataga
    37741 tattaaaaag agtgttagcg acctagcggc agctttactc ttaagtgcgt ttgctgccat
    37801 tgacagcaag gtcaaagctg atgaaacagc aggggcatac cgttatgatg tgtctaaaca
    37861 aaacacttac tatcaaacta tcagctccat taaccagcaa cgacctggtg ccactctcga
    37921 cgaatgaggt gattattatg gaacccttac ttcatttact tcccaaagtc gtaccagtac
    37981 ttatacactt ggtagacaaa gccaacgtat catggttaac agtgatatta cagttaccta
    38041 tactcttaaa gacaatttgg tagcccttca taaggaatat aaaacctttg tcaaaaaaat
    38101 attacagata aaccgatcac cagtgactac gacaaggcta aggttattta taaccattta
    38161 atcaacgaat acacttacgc cacaaaataa cttagcacca atcgcaaaac cgtaagcagc
    38221 atcaacaatc atactcctaa agctctttat cgtagcaagt gtggtgtttg tcaagcttat
    38281 gccgtcatgt ttaaagatat ggcagaagct gcaggcttat cagcttggta tgtgataaaa
    38341 aaggattgaa tgagcaccat gcttgaaaca tcgttaccat tcatggtgtt aattcctacg
    38401 ttgatgctac ctggaatgat tcagcataca ccacaaggta tttccttgct ggaaaagacg
    38461 tgaggaatac tgagtaccgt ttagatagcc agtacaacca cttggctaat gctattttaa
    38521 atatcagcta ctaaaaaggc taaactaaca acaactacat ttttcaacta gaaaggccta
    38581 aacaatgacc aaaaaacagt tttatcttat cttagctatt agcatactgt gttttattct
    38641 tgccgtcagc cctaaaccac caattcctaa acacactatt gaaaggaaaa ggactgcgat
    38701 gaccataggc cactcaaaac aaaaccctca caaaaaagaa gcccttaaac acaaaaaaaa
    38761 taaaaataag gctctatttc ttccaagtgg ggacagcgct atcaaatctg ttattagcat
    38821 gacagttaga ctcctgttag atgaccaatc ttagctctcc taaaatcagt ggacactacc
    38881 atttcggtag tgttcttttt taagctaatc tcatcaccac gctttcttca agctaaaaaa
    38941 ctgatcatga aagagcaacc ccatcaccct aacagcccac tttgcccgca ctttcttaaa
    39001 aagttaggag aaaacgatat accaattatt ttctgatccc agctccctat cattaacaag
    39061 atgtgtagca cggacctaca tacaggtaag ctagagtcat tctcgctatt tcggacaaaa
    39121 agaggccggt agttccctga cctcttcttt atttatcttg taacactcct cttcttagcg
    39181 agacttacta gcacataatt cttaagcact cttatcattt agactaggaa gaacaccatc
    39241 tgaatgaagc aaatgatgcg tcagatctgc cagagtatca tctccataag taatccctgt
    39301 ttggtgctgt ttctgatgaa aatcagatga ctccttaact ttagcagtca cctgctggtc
    39361 acttggatga aaattaattt ctctcttggc ttcagccgca actggctcga ggaacaactt
    39421 attgacatta cggtcttcct ccaaatgatt aaggatagca gtatcatctt ctaacgaaag
    39481 aaccttcttg ggtaacaaaa aggggttatt tagccttggc tcagtaacga cttccttggc
    39541 tactcgtgat agtttattat tgtcttcctc aggtatcaaa cggttaggca atcgatgcaa
    39601 ttcttccggc tatgaggcgc tcacagctac ttcagaagaa acctccaagc cctttcctgt
    39661 ttgcctgtct aaagcaaccg gcaaattatt aactaacttt ttaacctgtc ctcagcgctc
    39721 atttcaacac taggaagagc tgtcgctggt tctagccagc taccaacttc tgctggtctt
    39781 accttaacat cgctggcagg cttctccttc tcatcttcat taggtctaaa aggctcaaac
    39841 cgccctgttg atttttcatc tatgaccttt atattgtctt ttactacatg agacagtggt
    39901 tcgacattta ccatagcttc atgctcgtta aggctctggt ctcgtttgaa tttaccagga
    39961 ataccaggag tcggtgttcc gacagattga tcggcttcag taggctcttt tacggagcct
    40021 tttttccata aaactgctgg aggaataata tccgtagagc cagccccata agtaatcgtg
    40081 gccagccccc cccctttgga ttaatagata ctttaatatt gtccggtaag gctccactac
    40141 ctcctgtggt taaaagggca cccgcatttt taatgagagt tgtcattcgt tcaataccag
    40201 caacgccaat atggttcaag tcatctactg gtaactgatc aacagatttc atggtgtatt
    40261 tccaagcttg cggttgaaca agaaaaacag ttcctttata cattgtgtta tgcatatcat
    40321 caatgacttt gaaatacctt gtatatttgg tttgtacatt agggttagca acgggaacag
    40381 tgctttcagg aactcctgac atcgtaaaaa tctctctagc agaagtttga aagccctcat
    40441 aaacatgacc cataccagga acagtctgag cggtcaaaga cttaccagaa ccatccaaag
    40501 caatgcgaat atctttcatc agatacatct gatcggtata ggtaaaccta accgtgttag
    40561 cctcacctcg atacaaaacc acttgggagg gctgatccga aaaaaactga gaggttgttt
    40621 cttccttata gccaactcca aaacgtctat cagacgaatg gactgaatct gccgcaactg
    40681 tactactcaa actgactagt aaagtagccg cacaaccaac taataaactg ctcgttttaa
    40741 ctttaacatc tcttaacatc atcatgttcc tttcattatt ttttatttag gaattcgtca
    40801 tactatattt tctcatatta gtctaacaaa aaactcgtaa ttctatataa atcatataaa
    40861 atgacgagct ttggcaaaga tgagtatagc aggatggaaa acagattgtt tctgaaactt
    40921 caaaggtatc ttcttgtcac gaactattct ttaattgaat cggttacact aaactagtcc
    40981 cattatttaa aaacaaactt taaatatgat tcatttcact ttttaagttt attaaatata
    41041 gagtgattag gagaaataag acgacctaat gataaaatca ttcctattgt atagcaaaca
    41101 acaatatcta aagttttcat accactcctc tactactata ctcagtgata gatagtcatt
    41161 tatatattta gtgaggccag ataatatttg tagcagcacc agctgctcca cacaaaagat
    41221 aaccttgcaa agggataaat acgcctgtct gagcacaaac tatcactccc tgcgcagcac
    41281 ctaccatccc tgtcaaaaag atatttgctc cgtcttttcc gcctccattt atgatagcca
    41341 gaccattttt tagcacttcc atatttttga agtctttttc attttaattt cactcttttg
    41401 tattttaaaa agctaagagt gatatctaaa ttcattggca taatcactat tttcttttat
    41461 cgataaaaac aaataatgac gctaccaaag ctccgataga taacatgttt accgattttt
    41521 ccgaaaggga taattgattg aaaattaaaa acactaaata tggtatagat ttatcaacat
    41581 ttttttatga atggcatcaa caatcattaa aaacattata gacgcatgca taataataaa
    41641 aatcgtatag atcatttaat ttgctgtata tcccaaatat gctccaccaa ctgtaaatcc
    41701 tacaacacat ccacctgtca atactggatg tggcagttta caaaatttca atccagaagc
    41761 taagcctcca agaccaccaa ttacagcatc tcctggagcg tttcctccac ttatactagc
    41821 catgtcacta attgttaatt ccttcattgt tgtcatcctt tccttcctct agaatccgcc
    41881 tgtagctcct gttacaccag cccaaagagt aatagctgtt ttagctccag gctacaccgc
    41941 aaactggaaa acctatagca gctccagcac tacctgcagc gataacccca ctgacatttg
    42001 cctgccaatt attcttacca ccctcaacct tggcaagctt ttctatagtc atttggtgaa
    42061 atgtttccag tttctttatc tccatatcga ataatttctt ttcataattc ttaaatttgt
    42121 ctcgttgcaa cctcgactag tacagaatat cataaagaac agtatcatgg tttcaaaatc
    42181 ttaaaaggct gtttttcatc atgaaatgtc tttttatcct ctctacactt acgctgtgac
    42241 aatagttaat taattaagaa gtttaaataa taccattcat gcttttataa atacctttta
    42301 agatttttga tggtagtgta aaatatcttg tgtaaacaca caaaaaggaa taaatcctgt
    42361 atagtagagt tacgaaactt actagaaaga gatttattcc catgactcag tttaccacag
    42421 aattacttaa cttcctagca caaaaacaag atattgatga attttttcgc tcctctttag
    42481 aaatagctat gaatgacctc ttgcaagttg aactatcagc ttttcttggt tatgaacctt
    42541 atgaaaaaga aggttgcaac acaggtaata gccgtaatgg gacttattct cgtcagtttg
    42601 aaacaaagta tggcttagtc aatttaatca tcccaagaga tcgaaacggc gagttttcac
    42661 cagttttatt accatcttat gctagacgag atgaccactt ggaagagatg gtgatcaaac
    42721 tctatcagac tggcgttacg acacgcgaaa tcagtgacat tattgagcgc atgtatggtc
    42781 accacttgtt tctgagtgga agcctcgtta caaaaaggtt atgacatcac ttgaaacaac
    42841 ggaaaatctc ctaactttct atcaatttcc acattacatt tggtctagta tttactctac
    42901 aaacttgatt gaatcactca ataaagaaat caagcgacaa agcaagaagg agggtggttt
    42961 ttccaaatga agaagcctta gaacgatgtc ttgtaagtat tttcgaagac tataatatta
    43021 agttcggagc tcgtattcat aaaggattcg gagtatgttt tgacacactt gat
//
LOCUS       DAUGOH010000015        40159 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUGOH010000015 DAUGOH010000000
VERSION     DAUGOH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40159
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.015"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            2..145
                     /locus_tag="VH957_000833"
     CDS             2..145
                     /locus_tag="VH957_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEQ8558757.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            157..1695
                     /gene="dltA"
                     /locus_tag="VH957_000834"
     CDS             157..1695
                     /gene="dltA"
                     /locus_tag="VH957_000834"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEQ8558758.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERLTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            1692..2948
                     /gene="dltB"
                     /locus_tag="VH957_000835"
     CDS             1692..2948
                     /gene="dltB"
                     /locus_tag="VH957_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEQ8558759.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKAFMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            2966..3205
                     /gene="dltC"
                     /locus_tag="VH957_000836"
     CDS             2966..3205
                     /gene="dltC"
                     /locus_tag="VH957_000836"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEQ8558760.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            3198..4448
                     /gene="dltD"
                     /locus_tag="VH957_000837"
     CDS             3198..4448
                     /gene="dltD"
                     /locus_tag="VH957_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEQ8558761.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            4479..5462
                     /locus_tag="VH957_000838"
     CDS             4479..5462
                     /locus_tag="VH957_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8558762.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            6077..7336
                     /locus_tag="VH957_000839"
     CDS             6077..7336
                     /locus_tag="VH957_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8558763.1"
                     /translation="MSWNWKKTSVLGTLSLASVLPLTACVSGGGKGVKETDGKTIVVS
                     VDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPTGASPDVFLAPFDRV
                     GGLGTEGQIAEVTLGNSKEFDDTVKKLVTIDGKTYGAPDVIETLVTYYNKDLVPQAPK
                     SFTELEVLQKDSKFAFASEPGKSVGFLAKWTDFYYGYGLIAGYGGYIFGDKGTKPSDL
                     GLGNDGTVEGLNYAKQWYGTWPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFK
                     DAGVNFGVMEIPTLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFY
                     DKTQEIPANLTARNYASKEGNELTKAVISQFENAQPMPNIPEMAEVWEPGANMFFNVA
                     SGKEEASKAAKEAAKTIKEAIEQKYAE"
     gene            7502..9205
                     /locus_tag="VH957_000840"
     CDS             7502..9205
                     /locus_tag="VH957_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEQ8558764.1"
                     /translation="MNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGP
                     KYGYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNRGDWEKDDSYVNMGW
                     LEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTPIFQSISNHKYDISDYYAIDPQF
                     GTKYDLQELIDLAHQMGIKIILDAVFNHASSDAVEFQDVLRYGKESKFFDWFMTHDEH
                     PSMDLVNYETFAGCNYMPKWNTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHD
                     FWRRFRQAVKAEKADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTS
                     KQLAEKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFIFMGI
                     PCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQQPALQEGAISID
                     YDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILTSNGVTKNKKQLLQDGYIVFS
                     N"
     gene            9231..11366
                     /locus_tag="VH957_000841"
     CDS             9231..11366
                     /locus_tag="VH957_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclomaltodextrin glucanotransferase"
                     /protein_id="HEQ8558765.1"
                     /translation="MRELHIKTYKLLTKSAVLLGLISFPLTVSAADNASVTNKADFST
                     DTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQGIIAKIKDGYLTDMGISAI
                     WISSPVENIDSIDPSNGSAAYHGYWAKDFFKTNQHFGTEADFQQLVKVAHQHHIKVVI
                     DFAPNHTSTAEKEGTTFKEDGALYKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNINPKVDQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFVFGEWFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKVL
                     ENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGVPNIYYGTEQ
                     YATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALAYGTTEQRWISDHVLVFE
                     RKFGNHVALVAINRDQTNGYTITNAKTALPQNSYKDKLEGLLGGQELIVGADGTISSF
                     ELGAGQVAVWTYEGEDKTPQLGDVDASVGIAGNKITISGQGFGNSKGQVTFGEISAEI
                     LSWSDTLITLKVPTVPANYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTV
                     PGEQLYLMGDVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKK
                     DSIGNVLWTSPETYSIKTGHEAQTITIKK"
     gene            11441..12745
                     /locus_tag="VH957_000842"
     CDS             11441..12745
                     /locus_tag="VH957_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8558766.1"
                     /translation="MVDNQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLEL
                     LEIVVLGIPALTGLYSLGNVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKLVA
                     HQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVI
                     ANQSFIRGKRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVD
                     FGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADLYEAATVDGVTVLQK
                     FRHITMPMIFAVAAPTLIAQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYK
                     LTTQTSPQFSMASAVTLIISVIVISVSLITFKKFKAFDMEER"
     gene            12745..13605
                     /locus_tag="VH957_000843"
     CDS             12745..13605
                     /locus_tag="VH957_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8558767.1"
                     /translation="MRKTYVSTSMKRKRFFTQLLTYLYLISLAIVILFPILVTVSSAF
                     RPGNTTAFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTGYA
                     YSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVRPMIAVQSLWAFMGPFGDF
                     MLAKFLLRAQENYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKNFV
                     SGLTSGGTKG"
     gene            14211..14342
                     /locus_tag="VH957_000844"
                     /pseudo
     CDS             14211..14342
                     /locus_tag="VH957_000844"
                     /inference="COORDINATES: protein motif:HMM:NF037788.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14527..15324)
                     /locus_tag="VH957_000845"
     CDS             complement(14527..15324)
                     /locus_tag="VH957_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8558768.1"
                     /translation="MTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHI
                     SNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLV
                     CLNEDSIGKFDWADLILTLDIENDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAN
                     LKDQADQFFKDEPYTLLTLPINNQERYEAISTLFPNLHVVDHMRELPSFEKKNLLLID
                     ESLDQFFVNSSQKLYCPRFSPEKGQVILEAIEWAKQRQLNKNHNLLV"
     gene            complement(15482..16318)
                     /locus_tag="VH957_000846"
     CDS             complement(15482..16318)
                     /locus_tag="VH957_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8558769.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            complement(16318..17679)
                     /locus_tag="VH957_000847"
     CDS             complement(16318..17679)
                     /locus_tag="VH957_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8558770.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFTYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            complement(17953..19200)
                     /locus_tag="VH957_000848"
     CDS             complement(17953..19200)
                     /locus_tag="VH957_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8558771.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            19444..20463
                     /locus_tag="VH957_000849"
     CDS             19444..20463
                     /locus_tag="VH957_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8558772.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            20579..22072
                     /gene="malQ"
                     /locus_tag="VH957_000850"
     CDS             20579..22072
                     /gene="malQ"
                     /locus_tag="VH957_000850"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEQ8558773.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVADGYLQEADLVGVDFGSDPEVVDYA
                     QIFQARRPLLEKAVQAFLATKEGIKELAAFEAEASWLGDFAEFMSLKEHFQNKALQEW
                     DDRAIVKREEAALHHYRELLAKKITYHKVCQYFFYQQWSALKIYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            22107..24371
                     /gene="glgP"
                     /locus_tag="VH957_000851"
     CDS             22107..24371
                     /gene="glgP"
                     /locus_tag="VH957_000851"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEQ8558774.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSTAEVEDVELEPSLGNGGL
                     GRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEDVDYGLIKDGISFDKTEIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     CLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(24628..25254)
                     /locus_tag="VH957_000852"
     CDS             complement(24628..25254)
                     /locus_tag="VH957_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEQ8558775.1"
                     /translation="MTYDKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRL
                     HQAAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTW
                     QFDQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDN
                     YSQASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(25549..25896)
                     /gene="ssrA"
                     /locus_tag="VH957_000853"
     tmRNA           complement(25549..25896)
                     /gene="ssrA"
                     /locus_tag="VH957_000853"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            25988..26602
                     /locus_tag="VH957_000854"
     CDS             25988..26602
                     /locus_tag="VH957_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEQ8558776.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            complement(26733..27518)
                     /locus_tag="VH957_000855"
     CDS             complement(26733..27518)
                     /locus_tag="VH957_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558777.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(27528..28226)
                     /locus_tag="VH957_000856"
     CDS             complement(27528..28226)
                     /locus_tag="VH957_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558778.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(28226..28597)
                     /locus_tag="VH957_000857"
     CDS             complement(28226..28597)
                     /locus_tag="VH957_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8558779.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            28782..31892
                     /locus_tag="VH957_000858"
     CDS             28782..31892
                     /locus_tag="VH957_000858"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEQ8558780.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKIMDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            31972..32985
                     /gene="pfkA"
                     /locus_tag="VH957_000859"
     CDS             31972..32985
                     /gene="pfkA"
                     /locus_tag="VH957_000859"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEQ8558781.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            33048..34550
                     /gene="pyk"
                     /locus_tag="VH957_000860"
     CDS             33048..34550
                     /gene="pyk"
                     /locus_tag="VH957_000860"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8558782.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            34768..35325
                     /gene="lepB"
                     /locus_tag="VH957_000861"
     CDS             34768..35325
                     /gene="lepB"
                     /locus_tag="VH957_000861"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8558783.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            35501..37315
                     /gene="glmS"
                     /locus_tag="VH957_000862"
     CDS             35501..37315
                     /gene="glmS"
                     /locus_tag="VH957_000862"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEQ8558784.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            37511..37846
                     /locus_tag="VH957_000863"
     CDS             37511..37846
                     /locus_tag="VH957_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEQ8558785.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            37953..38594
                     /locus_tag="VH957_000864"
     CDS             37953..38594
                     /locus_tag="VH957_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8558786.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            38604..39233
                     /locus_tag="VH957_000865"
     CDS             38604..39233
                     /locus_tag="VH957_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558787.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQNVDAKEKALDLLTRLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            39249..40085
                     /locus_tag="VH957_000866"
     CDS             39249..40085
                     /locus_tag="VH957_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8558788.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     ALLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQSGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT        12558 a         6714 c         8145 g        12742 t
ORIGIN      
        1 tatgataaaa aacaaatcaa gaatgagagg aattgctgtt tttattggca agacaatttt
       61 attttatctg attttaatgt tgctggtcta tttctttggt tatctaggac atggtcaaag
      121 taactttatt tataatgaat tttaggagat tgactgatga ttaaggatat gattgacagt
      181 attgagcagt ttgctcagac acaggctgat tttccagttt atgattgttt aggggaacgc
      241 ctcacttacg gacaactcaa aagagattct gatagcattg ctgcatttat agatagctta
      301 gctttactgg caaaatctcc agttttggtt tttggggcgc aaacttatga tatgttagct
      361 acttttgtag ctttaaccaa atctggtcat gcctatatcc cagtagatgt gcattcagca
      421 ccagaacgta ttttagcgat tattgagatt gcaaagccca gtttaatcat tgctattgag
      481 gaattccctc ttactattga agggatttcc cttgtctcac tatcagagat tgagtcagca
      541 aaattagcag aaatgcccta tgagcgaaca cattctgtta aaggagatga taattattac
      601 attattttca cctctggaac aacgggtcaa ccaaaagggg tgcaaatttc acatgacaat
      661 cttttgagct ttaccaactg gatgatcgaa gatgcagcat ttgatgtacc taaacagcca
      721 caaatgctgg cgcagccacc ctattccttt gacctttctg tcatgtactg ggcacctacc
      781 ttggctttag gtggaacctt atttgcactt ccaaaagaat tggtggcaga ctttaaacag
      841 ttatttacaa cgattgcgca acttccagtt ggcatttgga catcgactcc ttcatttgct
      901 gatatggcca tgcttagcga tgatttttgc caggctaaga tgccagcttt aacgcatttt
      961 tattttgatg gcgaagaatt aaccgtttct acggctcgaa aactctttga acgtttcccg
     1021 agtgccaaga ttatcaatgc ctatggacca acagaagcga ctgtagcctt atccgctatt
     1081 gaaattacca gagaaatggt ggataattat acccgcttgc cgattggcta ccccaaacca
     1141 gattctccga cctatattat tgatgaagat ggtaaggagt tatcttcagg ggagcagggt
     1201 gaaattattg ttacagggcc tgctgtgtca aaaggttacc tcaacaatcc tgagaaaacc
     1261 gcagaagctt tctttacttt taaaggacag cctgcttatc atacagggga cattggctca
     1321 ttgacagaag ataatatttt gctgtatggt gggcgtttgg attttcagat taaatatgct
     1381 ggttatcgta ttgaactaga agatgtttcc caacagttga atcaatcgcc aatggtagca
     1441 tcggctgtgg ctgttccaag gtacaataaa gaacataagg ttcaaaatct cttggcctat
     1501 atcgttgtca aagatggggt taaagagcgt tttgataggg aattggagtt aaccaaagct
     1561 atcaaagcct ctgttaagga tcatatgatg agttatatga tgccttctaa gtttctttat
     1621 cgagatagtc taccattaac tccaaatggt aagatagata ttaaaacttt gattaatgag
     1681 gtcaataacc gatgatgatg ttttttagcc acattcccta catggaacct tacggtaacc
     1741 ccatttactt tgtctatctt attttggctt tcttaccagt catcattggg atttttaaac
     1801 aaaagcgctt aagcacttat gaaaccttgg tgagtttggt atttattctc tttatgtttg
     1861 gaggagatca ttatcaacaa ttagttgctt ttctctttta tcttttgtgg caaatcatca
     1921 gtgtttttgc ttaccagaaa taccgtgaga aagctaatag tgcaggagtg ttttacttag
     1981 ctattgcgat ggccttattc ccccttatct gggtcaaagt tgctccccta acaggtcctt
     2041 cttctcaaac actctttagt tttctaggga tttcatattt gacctttaaa agtattggaa
     2101 tgattattga gatgcgtgac gggactctcc aagaggttcg tttaccggat tttattcgct
     2161 tcatgatttt cttccccact ttctcaagtg gccccattga tcgcttcaga cgttttcagg
     2221 aagattatca taaacttcct gaacgtgatg attattttgc aatgctcaat aaggcagtca
     2281 tgtatctcat gttaggtttt ctatacaagc atatcatttc ctattgtttg ggtggcatct
     2341 tacttcctct ccttgaaaat aaggctttta tggttggtgg ctactttaat aaggaaacta
     2401 ttctggttat gtacgtgtat ggcttgaatc tcttttttga ctttgctggt tattcgatgt
     2461 ttgcgattgg tatttcctac ctattgggta ttcgaacacc agaaaacttt aacatgcctt
     2521 tcttatctgc aagtttgaaa gatttttgga atagatggca catgagtttg tccttctggt
     2581 ttagagatta tgtgtttatg cgattggttc atctattgat taagcataaa acctttaaaa
     2641 accgaaatgt cacttcaggt gttgcctatc tggttaatat gctagtcatg ggattttggc
     2701 atggcttaac ctggtattat atcgcttatg ggcttttcca tggtatagga cttattatta
     2761 atgatgcttg gattcgtaag aaaaaagaaa tcaaccgtca ccgtaagaaa aaaggcttat
     2821 cacccctctt tcaaagcagg gcattccatg tcttatgtat cgtggtaact ttccacgttg
     2881 tcatgttttc acttctgtta ttctctggtt ttttaaatga cctttggttt aacagaccac
     2941 tacattaata aaaggaagta taaaaatgtc tattgaagaa actgtaattg aattgtttga
     3001 ccgtttgttt atggaagatg tttcagagat gatggacgaa gacttgtttg atgcaggtgt
     3061 gttggatagt cttgggacag tcgaattgat tgttgagtta gagtcaacgt tcaatattaa
     3121 agtacctatt tcagaatttg gtcgtgatga ttggaacaca gtaactaaga ttgttcaagg
     3181 tgtagaggaa ttgcaacatg cttaagagac tctggttaat tctaggtcct cttcttattg
     3241 cctttgtttt agtagtgatt actattttta gttttcccac acaacttgat cattccatag
     3301 ctcaggaaaa agcaaatgcc gttgcgatca cagatagttc ttttaaaaat ggtttgatta
     3361 aaagacaagc tttatcagat gagacttgtc gttttgtgcc tttttttggt tctagcgaat
     3421 ggagtcgaat ggatagtatg cacccttcgg tgcttgcaga gcgctacaag cggagctata
     3481 gaccattttt aattggtaag agaggatcag catctttgtc gcattattat ggtatgcaac
     3541 aaattaccaa tgaaatgcaa aagaaaaaag ccatctttgt agtatctcct caatggttta
     3601 ctgctcaagg gattaatcct agtgcggttc agatgtactt gtctaacact caagtgattg
     3661 aatttttact aaaagctaga actgataaag aatcacagtt tgcagcaaag cgtttgcttg
     3721 agcttaaccc tggtgtgtct aaatcaaact tattgaaaaa agtaagtaag ggtaagtctc
     3781 ttagtcggtt agacagagct attttgaaat gtcaacatca agtagcattg agagaagagt
     3841 ccctttttag ttttttaggc aaatctacta actatgaaaa aagaattttg cctcgcgtta
     3901 agggattacc taaagtattt tcgtataaac aattgaatgc attagcaact aagagaggcc
     3961 aattagcaac aaccaacaac cgttttggga ttaaaaatac attttatcgt aaacgaatag
     4021 cacctaaata caatctttat aagaatttcc aagttaatta tagttacctg gcgtcaccag
     4081 aatacaatga ttttcagctt ttattatcag aatttgctaa acgaaaaaca gatgtactct
     4141 ttgttataac tcctgttaat aaagcttggg cggattatac cggcttaaat caagataagt
     4201 atcaagcggc agttcgtaaa ataaaattcc agttaaagtc acaaggattt catcgcattg
     4261 ctgacttctc aaaagatggt ggtgagtcct actttatgca agataccatc catctcggtt
     4321 ggaatggctg gttagctttt gataagaaag tgcaaccatt tctagaaacg aagcagccag
     4381 tgcccaacta taaaatgaac ccttattttt atagtaaaat ttgggcaaat aggaaagact
     4441 tgcaatagta aaataatatt agaaaacgag gataataagt ggtcattatt gctgtggtga
     4501 ttttttttgg agtgatacta ggtattttga tagttgaata tggtcaaaag cgctcctttt
     4561 caagttggtt ggttgagaaa atgtttgctt atagaaagta taagttatct aaaaaagttg
     4621 ataattataa gggggttgag acgcagcgta atcgtaatat cccttatcat ctagataatc
     4681 ctgaagagat agtaggtttt tcaactcaag aatacgatgt gaacgggatg caagttttta
     4741 ttattaatga tcaaaagcaa agtcatcagc ctgttattta ttatctttat ggcagtgtct
     4801 atttacgacg acccgaaaaa cttcatttta agacggttaa gcatcttata cagctgacta
     4861 atgccaaggt tgtttttcct aactttccta aagtaccgta tgctacttat caagatgtct
     4921 atcctaaatt agttgaagct taccagcaat tttgcttgtc taatggaccg agtcaagtta
     4981 gtgtcattgg tgattcttct ggtgggggta tggctttggc gtttgctaag tatatacgag
     5041 atactaaaac agcaccccag ccaaagcaat taattcttat atctccttgg ttagatgtta
     5101 gttttaaaaa tcaagcctac aaggattttg aagcagaaga agcttaccta gatgctcgtc
     5161 gtcttcgtga tataggtgaa ctatgggcag gtggtcaagg taatatgcaa cttccttatg
     5221 tcagtccttt gtatggtgat tatgaggatt tgcctgaaat aacgaccttt gttgggacaa
     5281 aagagatttt ttacccagac attatgtctt tacatgatca attaacaaga caacgaattg
     5341 ctaatcagct gattattgca gaaaaaatga ttcatgcgta tgttattttt ccaataagag
     5401 aagctaagca agctcgaaaa caaattgcag aactagtgtt gaaaacagta gagcatacct
     5461 gaattactat tttgtaatct aagacctaat tgataatccc ttggacacac tcttcatcag
     5521 gatttcctat ctacctttct gataagtagt aacgagctca gtaggagatt catccttcaa
     5581 aacattgttt agagtgatat ttttgtcttt aattccgatg tgttgtaagg tatgattgat
     5641 atgttccata agagtctttc taatgagagt ttggttgctt ttcattataa atcttatggg
     5701 acttttttga tattcaaaaa gctctataat ctctacagtg gatttaccca ttcaagagat
     5761 tatagagctt ttgttttatt tacgctgacg aaataaagtt gtagaaaaaa agaaaggaca
     5821 gacttgtgtg acagtaaatg ccttgttttc aattagcagg aaaactactg atatgctctt
     5881 aaaagaaaag aaaagtaaaa aagttattga caaatgaaag cgattacgat aaacttaact
     5941 taaacgttta agtttcgaaa ctattactgt tattaatttt aaatgcctta tgttatcttt
     6001 tatttgctaa tatgatgaga gtagatagat gatttgattt gtgtttaaga aaaaaccatt
     6061 tcgggaggaa catgttatgt catggaattg gaaaaaaaca tctgtgcttg gaactttatc
     6121 cttagcttca gtgctacccc taactgcttg cgtaagtggt ggtggtaaag gcgttaagga
     6181 aacagacgga aagactattg tagtctctgt tgatgaggga tatgttgatt acattaagag
     6241 tattaagggt gagtttgaaa aagaacataa agtcaccgtt aaagtcaaaa aagaaggtat
     6301 gatggatact cttgataagc tatcaacgga tggtccaaca ggagcttcac cagatgtctt
     6361 tttagcacct tttgaccgtg taggtggctt aggaactgaa ggtcaaatcg ctgaggttac
     6421 tttaggaaac agcaaagagt ttgatgatac ggttaagaaa ttagtaacca ttgatggtaa
     6481 aacttatggt gcaccagacg taattgaaac tttggtaact tattataata aggatttagt
     6541 gcctcaagca cctaaaagct ttactgaatt agaagtctta caaaaagatt ctaagtttgc
     6601 ttttgcctct gaaccaggaa aatctgtagg tttcttggcg aaatggacag acttctatta
     6661 tggttatggt ttaattgccg gttatggcgg ttatatcttt ggtgataaag gaaccaaacc
     6721 aagtgattta ggcctaggta acgacggaac tgttgaaggg ttaaactacg cgaaacagtg
     6781 gtatggcact tggcctcaag gaatgcaaga cactaaaaaa gctggtgatt ttatcactga
     6841 acaatttatt tctaaaaaag ctggtgtcat tattgatggt ccatgggcag ctagctcctt
     6901 taaagatgct ggtgttaact ttggggtaat ggaaattcct actttgacaa atggtaaaaa
     6961 ataccaaccg ttcgcaggtg gtaaagcttg ggttatttca aactattcta aaggaaaaac
     7021 gactgctcaa aaattccttg attatgtgac caatgctgaa aaccaaaaac gtttctatga
     7081 taaaacacaa gaaattccag ctaacttaac agcacgtaac tatgcttcta aagagggtaa
     7141 tgagttaacg aaagctgtga ttagtcagtt tgagaacgca caaccaatgc caaatattcc
     7201 agaaatggct gaagtttggg aaccaggtgc aaatatgttc tttaacgtgg cttctggtaa
     7261 ggaagaagca tctaaagctg caaaagaagc agcaaaaact attaaggaag ctattgaaca
     7321 aaaatacgct gaataaggca aagaagggag gctgggataa agaagtacgc ccagcttcta
     7381 tttctgttag tttgatgaag atgaaacaga tactaaaaat atagaagtat gagtcgctct
     7441 gctatttttt cgttttaaag aaaaagaagt aatcgtcaat actttattaa tggaggtaga
     7501 aatgaatgtt gccggaatgc tccatattcc tgattcgagg tattgctttg ccatatctca
     7561 aaaggaactt gtcatccgat tacgcgtggc caaagaagat agaggtatta ctgttaattt
     7621 ggtccacggg cctaaatatg gttatcatga attccaagaa gaattggaaa tgtcagttgc
     7681 ctatacagac catacgcatg cttattatga aactacttta acattagacg atgtgaggtt
     7741 ggcctacatt tttaaaattg aagaagaagg tcaaacctat tattttagtg aagatgggtt
     7801 aactactagt tacgattttt caaatgggtt ttataatttc ttccaaatgc cttatatcaa
     7861 tgctgttgat gtccatcaag tcattccttg gacaaaagac gcggtttttt atcaaatctt
     7921 tgttgatcgc tttaaccgtg gggattggga aaaagatgac agttatgtca acatgggttg
     7981 gttagaaaaa ccgactccta aaagttttgc tggtggagat ttaaagggaa ttacagaaaa
     8041 attagattac ctcaaagatt tagggattac tgtcatctat ttaacgccaa tttttcaatc
     8101 cattagtaat cacaaatatg atattagtga ttactacgct attgatccac aatttggaac
     8161 taaatatgat ttgcaagaat tgattgattt agctcaccaa atgggaatca agattattct
     8221 agacgctgtc tttaaccatg ccagcagtga tgccgtggaa tttcaggatg tcttgagata
     8281 cggtaaagag tctaagtttt ttgattggtt tatgactcat gatgaacacc catccatgga
     8341 cctagtaaac tatgaaacct ttgctggatg taactatatg cccaaatgga atacctcaaa
     8401 tagagacgtg caagactatc tgattgagat tgggcgatac tggattaaag aattttgtat
     8461 cgatggttgg cgcctagatg tttctgatga agtatctcat gatttttggc gacgtttccg
     8521 tcaggcggtt aaagcggaaa aagcagatgc cattttaatt ggggagaact ggcatgatgc
     8581 ctatccttat ttggcagggg atcagtatga tgggataatg aattatgctt tcaccaaagc
     8641 ctgtttggat tactttgctt ttgaaaccat gacatcaaaa caattggctg agaaattaag
     8701 caacattttg atgcgaaaca cttggcaagt caatcgcatg aacttgaatc ttttggattc
     8761 tcatgatacg catcgtttct tcactcaagt taagggttcc aaagataaat tgttagctgc
     8821 tttagcattg ctctttatct ttatgggcat tccttgcttg tattatggga cagaagtggc
     8881 aatggaaggg ggttacgacc ctgattcgcg tcgcggtttt ccttgggatg atgctgagcg
     8941 ggacaaggat ttctttagca aagtaaaagc gattattgct cttcgccaac agccagctct
     9001 tcaagaagga gctattagca ttgattatga cgaagactgc ctcattctga aacgcagctt
     9061 aggtgagcaa agcatttcac ttgttcttaa caatggtgag agtgcttatt ctattaagga
     9121 aggaggacag attttgacaa gcaatggggt aactaaaaac aaaaaacaat tactccagga
     9181 tggatatatt gtgtttagta actaaaaggt tatttgaaaa ggaaaaagcg atgagagaat
     9241 tacatatcaa aacttataag ttattaacga aaagtgctgt tttacttggc ttaatttcat
     9301 ttccactaac tgtttctgct gccgataatg cttctgtcac caacaaagca gatttttcaa
     9361 cagatacgat ttatcagatt gtaacagatc gttttaacga tggtaatacc tctaataatg
     9421 gtaagactga tgtttttgat aaaaatgacc ttaaaaaata ccatggaggt gattggcaag
     9481 gaatcatcgc caagattaag gatggttacc tgacagatat ggggatttct gccatttgga
     9541 tttcttctcc tgttgaaaat atcgacagta ttgatccttc taatggaagt gctgcatatc
     9601 atgggtattg ggctaaggac ttctttaaaa caaaccagca ttttggcact gaagcagact
     9661 ttcaacaact agtcaaagta gctcatcaac accatattaa ggtagttatt gattttgctc
     9721 ctaatcatac gtctacagcc gaaaaagaag gcacaacttt caaagaagat ggcgctttat
     9781 ataaaaacgg taaattagtt ggtaaatttt cagatgataa agacaagatt tttaatcatg
     9841 aatcttggac cgattttagt acttatgaaa attctattta tcattcaatg tacggactag
     9901 ctgatttaaa taacattaat ccgaaagttg accagtacat gaaagaagct attgataaat
     9961 ggttagacct gggtgttgat ggtatccgag ttgacgctgt taaacatatg tcacaaggtt
    10021 ggcaaaaaaa ttggttgagt catatctatg aaaaacataa tgtctttgtt ttcggggaat
    10081 ggttctcggg acataccgac gatgattatg atatgacgac atttgctaac aatagtggga
    10141 tggggctttt agattttaga tttgccaatg ctattagaca gttgtataca ggtttttcaa
    10201 cgtttaccat gcgagatttt tacaaggttc ttgaaaatag agatcaggtg actaatgaag
    10261 tgacagacca ggtgaccttt attgataatc atgatatgga acgcttcgca acaaaagtgg
    10321 ctaataatca aactgctgtt aatcaagcct atgctttgct tttaacatct agaggtgtgc
    10381 ctaatattta ttatggtaca gagcagtatg caacaggtga taaagatcct aataatcgtg
    10441 gtgatatgcc aagttttaat aaagagtcac aagcctataa agtgattagt aagctagctc
    10501 ctttaagaaa acaaaatcaa gctttagctt atggaacaac tgaacaacgt tggattagtg
    10561 atcatgtttt ggtatttgag cgtaaatttg gtaatcatgt cgcactagtg gctattaata
    10621 gagatcaaac gaatggttat acaattacta atgctaaaac agccttgccc caaaatagct
    10681 acaaggacaa attagaaggt cttcttggcg gtcaagaatt aatagttgga gcagatggca
    10741 ctattagtag ctttgaactt ggagcggggc aagtcgctgt atggacttat gaaggagagg
    10801 acaagacacc acaacttgga gatgtcgatg cttcagtggg tattgctgga aataagatta
    10861 ctatttcagg tcaaggtttt ggtaattcta aaggtcaagt gacttttgga gaaatctctg
    10921 ctgagatcct ttcttggtca gataccctta tcaccttaaa agtaccgacg gttccagcaa
    10981 attattataa catttcagtg acaactgccg ataagcaaac cagcaatagt taccaagcct
    11041 ttgaagtatt gactgataaa caaattcctg ttcgtttact catcaatgat tttaagacag
    11101 taccagggga acaactatat ctcatgggtg atgtttttga gatgggggca aatgacgcta
    11161 agaatgctgt tggtcctcta tttaataaca ctcagaccat tgccaagtac ccaaactggt
    11221 tctttgatac tcatctacca atcaataaag aaatagcagt caaacttgtt aaaaaagata
    11281 gtattgggaa tgttttatgg acaagtcctg agacttatag tataaagaca ggtcatgaag
    11341 cacaaaccat tactataaaa aaataaatta gtcagcttaa aaggaagtta gtatgataag
    11401 gaggataacc ttaaatcatt tatgagaaga ggaataaaaa atggtagata accaaagaca
    11461 acagaagcct aataaagcca tgtggctatc tgttatccca ggtttgggac aactatacaa
    11521 taaacaaatc gttaaagggg gagtcttatt agttgttttc ttcctagagc tactagaaat
    11581 tgtagttcta ggaattcctg ctttaacagg tctttacagt cttggaaatg ttccaatgca
    11641 agatcactcc ttatttatgt taattaaggg ggccatgcaa ttaattactc tagtcttatt
    11701 tggtattttt catttggttg ctatgagaga tgctaaatta gttgcacatc aaatgaatga
    11761 aggcaagaag gttccggtga cggctaaaga gacccttgaa gcgatttatg aaaaaggatt
    11821 tccttacttg ctcatcattc cggcttattt agcaatggct ttcgctatta tttttccagt
    11881 tttagtgacc ttgctgattg cttttaccaa ttacgatttt aggcatattc ctccgtatcg
    11941 tttattggat tgggtagggt tgaagaattt tcttaatatc ttagaattaa gcaccttcaa
    12001 aacagcattt acatctgttt tgtcatggac gctgatctgg acattagcag cgacaagtct
    12061 tcaaattgtt attggaattg caacggctgt tattgctaat caatccttta tcagaggaaa
    12121 acgtctcttt ggtgtgatat tcttgttacc atgggctgtt ccagcattta tctctattat
    12181 gagttttggt aatttcttta atgattccat tggggccatg aatgttcagg ttcttccttt
    12241 catcgagaaa ttccttcctt tcgttgactt cggaattgtg tcctggaaga cagacccctt
    12301 ctggacaaaa gtggctgtta ttatggtgca aggttggcta ggatttccct atatctatat
    12361 tttggtatca ggtattttac aggcaattcc agctgattta tacgaagcag caaccgttga
    12421 tggtgtgaca gtcttgcaga aattccgtca tatcaccatg ccaatgattt ttgcggttgc
    12481 agcaccgacg ctgattgcac agtacacttt taacttcaat aatttctcta ttatttatct
    12541 gtttaataat ggggggcctg gtactgttgg gggcggagct gggacaactg atatcctcat
    12601 ttcctggatt tacaagttga ccacacaaac ctcacctcag ttttcgatgg cgtcggcagt
    12661 aaccttaatc atctctgtaa tagtgatttc ggtatccttg attaccttta agaaatttaa
    12721 agcttttgat atggaggaga gataatgaga aagacctatg tttcaacatc catgaaacgc
    12781 aaacgtttct tcacccaatt attgacctat ctctatctaa tctccttagc gatcgtgatt
    12841 ttattcccga tactagtgac ggtcagttca gcttttagac caggaaatac cacagccttt
    12901 agttttcatt ttgatgggcc atggaccttg tctaacttta aaacactctt tcaagatacc
    12961 ttatacttaa gatggtattg gaatacctta atcgtggcat tcttcaccat gctcatacaa
    13021 gtaacagtca tcactttgac aggttatgca tatagccgtt acaatttctt tggacgcaaa
    13081 aaaagtttaa tctttttcct agtcgtacag atggttccta ccatggcggc tttaacggct
    13141 tactttgtta tggcttggct ctttaatgcc ttaaaccaat actggttctt gattttgatt
    13201 tacgtcggtg gtggtattcc aatgaatgcc tggttgatga agggttattt tgacacggta
    13261 ccttatgact tggacgaatc tgctaagtta gatggttctg gacactttag gaccttctac
    13321 caaattgtcc ttccacttgt gcgaccaatg attgcagtac aatccttatg ggcttttatg
    13381 ggtccttttg gagacttcat gttggctaaa ttccttttac gggcgcaaga aaattatacg
    13441 gtagcagttg gtcttcaatc gtttattacg aatgatgcta gaaatcctaa ggtaacctta
    13501 tttgctgcgg gagctattct gattgcagtg cctatttcag ttctcttttt cttcctacag
    13561 aaaaatttcg tctcaggttt aacaagtggt ggtaccaaag ggtaacctga caaggagtaa
    13621 tgtttaatgc cagataaaaa acaatttcct atttcttaca tttcacattg cctttctcct
    13681 agggcaatgt ttgccagccg agctcagttt acttggtggc aaaaccttct tattattgtt
    13741 tttttgaacg ccttaataat gattccagtt acgttacact atgctaacat gacaacgtat
    13801 cccttggaac ggattgtaac taagagtttg tcgcctatca cagacaaaac ctatcacgca
    13861 ttgacccaag gaaaggttga ggaaaatacc tttcagggtc aatctctgat tcgacgagat
    13921 ggtgaattgg ttttggctgt cttaccgaca aaggtcgatt tagagaaatt ggcatcagaa
    13981 tcaaccaggc aaattattgt gacaaaaaaa gaatggcgtt ttgttacccc tgaaggcaag
    14041 gaactccgtg ctcacgttag aggccagcag cagtcgctcg ccgacctcac aacagttaaa
    14101 gcagtgaagg actttgtcaa tcagcaatgg tatgacagta ataaagccag tgtacttggt
    14161 tttcttctgt tgacgtttgt tctcatggtg tatgtgggca cccttattgt gattggtcta
    14221 ggcgctttct ttttgacctt gaccaaacga tcacggctgt ttatgattcg aaatttttca
    14281 gaaggtcttg gtttgatggt caattgtttg gcctggccaa gtctattggc aattgctctt
    14341 agtttcttta ttcaggatcc cgtattgatt atgaattgcc aagtatttgg taccttatta
    14401 atgctgacct gggtgttcta caaaacacag tttagagatt cgttaccatc ctaagagaac
    14461 tctgacaccg atgtcatatc aaaacccctt gcacttcagt tgaagtgcaa ggggttttgt
    14521 gtgctattag acgagaagat tatgattttt gttgagttgt cgttgtttgg cccactcgat
    14581 ggcctctaag ataacttgcc ctttttctgg ggaaaaacgt gggcagtaga gtttttgcga
    14641 agagttcaca aagaattggt ccaaactctc atcaatgagt aaaagatttt tcttttcaaa
    14701 gctaggcaac tccctcatgt ggtcaaccac atgtaggttt ggaaaaaggg tggagatagc
    14761 ctcataccgt tcttgattgt tgatagggag agtcagcagg gtataaggtt catccttaaa
    14821 aaactgatct gcttggtctt ttaggtttgc gtaatctgtg ttaatttgga agaagagagg
    14881 gtcattaaca aagctatcaa tagcaattaa gggcttgaaa ttaagtttcc cgattttgta
    14941 aaaggtatca ttttcaatat ctaaggtcag aataaggtca gcccagtcaa attttccaat
    15001 actatcttca ttaaggcaaa cgagctgata gtcctgctca tgcaataggc gggatagaaa
    15061 gctaatggta tgcagttgtt cagccctagc taaaatgcta tctgcatatt tgtaatacag
    15121 gacaacactg tttgattgtt gtgtgactaa tgacctggct gcctgattag gtgtatagtt
    15181 aagaaggtta ctaatatgta gcactttatt gcgggtttct tcgctgattt tttgatcatt
    15241 gcgctggttt aacacgtaag atacggtcgc cacagaaacc ccggcttctc gtgcaatatc
    15301 tttaatggta attttagatg tcatcatttt gttatatccg aattcatggt aaaagtcaag
    15361 gaatcattaa tacatttggc tgatctgaag ataaatgtga ggactaatat gattatctac
    15421 ggccttattt atcaaaaacc tcctaaaggg cttgccctta gaaggtttgg tatgttgtaa
    15481 cttatttaac agaaccacct gtgatgcctt caacatagta tttttgcata aacatgaaga
    15541 ggagagtgat tgggacggca attaagacag aaccagcagt gaaggccata aaccagttgt
    15601 taatggtatc tggctgaagc attgaaaata gtccaatagc aacggtatat ttacttgtag
    15661 catcacctaa aataacttgt gcaaagataa agtcaatcca aggccccata aaagcaagaa
    15721 gggcagtata gacaatgatt ggttttgcta aaggaagggt tattttaaag aaaatatcca
    15781 tacgagtagc gccatcaatc atagctgatt catcaagtga ataaggaatg gtatcaaaaa
    15841 atccttttgc aatgtaaaaa ccaagggctg cacctgagga ataaacaagg acaagtgctg
    15901 ttagggtttg cgtcaaacct aaggccttta agatatagta gatggcaatc atgctcatga
    15961 aaccagggaa catatttaaa ataagggcta gttttaaaaa gccattgcga aacttaaatt
    16021 taattcggct aagagagtag gctatggcaa cagttatgaa ggttgaaata atacatgtaa
    16081 aagtggctac aataagagta ttcataaacc attttccaaa aggaaaggtt tcattagtaa
    16141 aaagattaat gtagtgattt aatgtaaaag tcttaggaat aaaataattg acgtaagcag
    16201 ttccttcgct acggaagcta gtaagaataa cccaagcgat tgggaagagc caaatgattg
    16261 agaggatgat taaagtagca taaacaagtc caagttgaaa tcgacgtttg tttttcatta
    16321 tttagccgct ccttccttgt aggatgctgt ccttgtataa gcaagtaagc taaagatagc
    16381 tgaaactgta aagattaaga taccgataac agaagctaaa ttgtagtcag cagctgtgac
    16441 ggttaattta tagagccaag tgaccagcaa gtctgttgtt cctgcctgat agtattctga
    16501 atttgttgga ccaccaccag taaggaggta aatgacgtta aagttattga tatttccgat
    16561 aaattgttga atcaagtttg gtgtcatgat caagagaatt tgagggaatg tgatagactt
    16621 gaagacttgg aatttgctag cgccatcaat ttcagcagcc tcaatttgtt cacttggaag
    16681 gttcatgata ataccagtcg caatcaacat ggtaaatgga ataccgatcc acatgttgac
    16741 aaaaatgatt gagaattttg cccaaagagg atcagataaa aatggcagtg agccattaat
    16801 caagccgatt ttattgagaa gagcatttag tgggccttcg tcattgagta agttccgcat
    16861 aatcaataat gagatgaatt gtggaactgc aatggtgata acaaagatgg ttcgccacat
    16921 ttttttccac tttaatcctt tggtattgat taacaaagca agaataatac caaagaagaa
    16981 attagttact gtggcaaaaa cagcccaaat caaagtccat gagaagatag gaaaaaaggt
    17041 tcctgccata cggccgctta aaacatttcc aaagttagca agtcccaccc aatcaaataa
    17101 agattttgga ggcaagtgat tatgatcaaa attggtaaag gccaaacaga tcatgtaaat
    17161 caaaggaaga atggtgaata aaagcacacc aatcagtggg atagccatta aagtcatatg
    17221 aaagcgacca tttgtaagtg tggcaagatc ttctttgaag cttggtatct tctgaccttt
    17281 ttgtttgaaa agataaaggt tacgagcact tttgagatta caccagtaaa tgtaagtaaa
    17341 gactaggcaa aaaatgagtg atgctaaacc aaaaataagc attagcatag agttatcgcc
    17401 atcaacagca acttggatgt taatcccatc aatagttttt gtagtcattc cctgagtttg
    17461 agtaccaaga gtgacaaggc cacggatagc agggatgatt tgggagacaa aagctactag
    17521 aaagataagt tcacttatta aaaataagat tcctttgata aactgtttgt tagcaaagtt
    17581 ggcaaatccc atgataatac tcgaaagttt aatatcccaa ctgcctcttt ttaaggcttc
    17641 tattacagat atatttggtg tcaagtttga ctgagtcata tagattctcc tttattttag
    17701 gatactagag tggtagttca gattcaatct cttgttagga tgaaatagct aagtgttacg
    17761 taaactttta aagagttaaa aatttaagta gcactaagct actagtaaaa caaaaacaag
    17821 taagagtgag actaagcttg aataaaatgt gatggagcct agttccactc ttcataaggt
    17881 aagtggaaag aactttttag aagtacttac cttgtgcttg ttttagtata gcagtgatga
    17941 catgagatca tattattttg ttgcagcgat atctttgtcg aattgttgca acttagtaag
    18001 gtagtcgctt tctttgattt taccgttgaa ggcatcacta agaatagcag cactttcagt
    18061 ccagaatgtg cccatttggc taagttttgg cattacgaca gtgtagtctg aagaagaacc
    18121 catagtgata acggttttag caagttcgtt tgattgaaca gcttctgaag attgaacttc
    18181 tttgttggct gggacaatgt tacgagtctt gaattggttt tcttggcttt cagcattagt
    18241 caagtaggat gccaatttgt agctagctgc gatacgtttt gtatcacctt tagctggtgc
    18301 ttggttgact gcgtaaagtt ttacacccaa gaatgctttt tgttgaaccg tttcgcctcc
    18361 aatagttact tttggataaa tagcaacacc aaggttttct ttaccgatag ctttttgagc
    18421 agcttcatag tcccacggtc ctgattcaaa agaagctact gaaccgtcac caaatttaga
    18481 cataacgttg ttagcatcta agctaacaaa acctttattt gaagcttggt ctgcgatcca
    18541 tttaagaaca gcagcgcctt tttcattgcc ccagttagta ccttttacat cttcaccgtt
    18601 ttccccaaat aaagtgttac caactgacat gaataatgga ccagtagcgt aagtgttagc
    18661 ttgtttaaag gtaccaccaa aagttgcttt tgtagtaatt gtatcatatg aagtaacgtc
    18721 ttcagcagct aattttgatt tattgtagaa aagaacttgt gattcaatac caaatgggaa
    18781 agcatatgtt ttccctttgt actgtgcacc gacgagcgcc tgatcagtag aagtagcagc
    18841 aatttcttta ttgtactttt ctggaacttc ttgaatagta ccagattcta caagttgacc
    18901 aagttgatca tgaggaagtg aaaagacatc ggcagcagtt gaggcatctt ttttgatttt
    18961 ttcttgtgct tttggatctt ctgattcaac cactttaacg gtgtaaccag aatctttttc
    19021 aaattttgca atggtatctg catatgattt tttagagcca gtcggtaccc aaagtttaat
    19081 agtctttgag tcagcgccag cttccttttt atcttttgaa cctgatccac atcccactaa
    19141 caaggtactt gcaagtgtca aacttgctcc gccgacgata actttttgcc atgatttcat
    19201 agctatttcc tcctaagata tatttcttac acttaatatt atgcaaccgc ttgcagaaaa
    19261 agtcaagcct tttttaaaaa aaaggtcgtt tttttaaaaa aatagtttag agaatttgag
    19321 ttaaaatgac aagggaatct tgattgaagt tgattttttg aaagataatt gtataatgga
    19381 aacgaaatac atgacaaacc catgataagg tttatctttg gtaaatatag taacgaggtt
    19441 aatatggtaa caataaaaga tgtcgctcaa aaggcaggtg ttaacccttc gacggtgagt
    19501 agggtattaa aagataatcg atctatttct atgaaaacaa aagagaaggt tagaaaagcg
    19561 atggcagatt tgggatatgt tccaaatgtc gcagcacaga ttctagcgag tggtttgaca
    19621 cacaatatag gacttgtttt tcctcctatt acaactagcg atagattaag tgaacctttc
    19681 tttatggaaa ttttgtcgac tattactaac gaagctaaag aatctcattt tactgtgtcg
    19741 attgctacag gtatatctct tgatgacctg atagagcaag tgaaactgat gcatcttcaa
    19801 aaacgagttg atggttttat tattctttat tctgatcaag atgatcctgt caaaaaatat
    19861 ttgatgacaa ataacttacc atttgtcatt gtaggtgctc cacaaggtga cactaataaa
    19921 accacttata ttgataatga taatcagcta atggctaaaa cagcagtaga acacctttat
    19981 caaaaaggcc atcacaacat attatttata acagatgatt tactatcaga agtaacttct
    20041 gagcgttatc ttggctattt gaaggggtgt tttaagcgat ctttaaaaac gaagccaatg
    20101 ctgttatttg atcgtaagga tcctgttagc gtagaaatat tgatggaaac tatatcttcc
    20161 tttaaagcaa ctgccttggt tgttgttggt gatgttctgg ctattcgtat ggtacagtta
    20221 ttatcttttt atgatataaa agtgccagat gatatgtcaa ttatcacttt taataattct
    20281 aattacgcta aattaattca cccttattta acgacatttg atataaatgt tgaaaatctt
    20341 ggaaaaatgt cttttaagca attacttgat attatcaatt ccaatgaaca gaatcttagt
    20401 cagactattt ttgttccttt tagtttaaaa caaagagaaa gcgtccgtga tattagtcat
    20461 taagagcaaa aaaaagtagc atttttaagg aatgttactt tttttaggaa actggttgac
    20521 ttacgcaagc gcttgcgtta taatctcatc atgaatagat ttcacaagga gaaaaatcat
    20581 gaacaaacgt gcaagcggta tcttaatgca tattagttcc ctgcctggga aatttgggat
    20641 aggcactttt ggaaaatcag cttttgaatt tgttgatttt ctagcagaga cgaaacaaac
    20701 ctattggcaa attctgcctt taacaacgac gagttttgga gattctcctt atcagtcatt
    20761 ttcagctatt gctgggaaca cacatttcat tgattttgaa ttacttgttg cagacggcta
    20821 cttgcaagaa gctgatctcg ttggcgttga ttttggttct gaccctgagg tggttgacta
    20881 tgctcagatt tttcaggcaa gacgcccctt attagaaaaa gcggtccaag cctttcttgc
    20941 aactaaagaa ggcatcaaag aattggcagc ttttgaagca gaagcgagtt ggttgggtga
    21001 ctttgccgag ttcatgtcat tgaaagaaca ctttcaaaat aaggccctac aagaatggga
    21061 tgacagagca attgtgaaac gcgaagaagc agccttgcat cattaccgtg agttgcttgc
    21121 aaaaaagatt acctatcata aagtctgtca atacttcttt taccaacaat ggtcagcctt
    21181 gaaaatttac gctaaccata aagggataga aattattggt gatatgccta tttatgtttc
    21241 tgcggacagt gtagaagttt ggacgatgcc tgagctattt aaagtagata gtgataaaaa
    21301 gccattgttt attgcaggtg taccagcaga tggctttagt gaagatggtc agctgtgggg
    21361 aaatccaacc tacaattggt ctgctcatga aaagtctaat tttgcatggt ggatttatcg
    21421 tattcaagaa agttttaaac tatatgatca gctaagaatc gatcatttta aaggcttctc
    21481 agatttttgg gaaattcctg ctggtgataa aactgctaga aatggccatt gggcctcagc
    21541 cccaggtata gcattatttt ctgcggttcg tgaggcctta ggagagcttc ctatcatcgc
    21601 agaaaacctt ggttatattg atgaaaaagc agagcagcta ttagcatcaa caggctttcc
    21661 tggcatgaag atattagaat ttggtttatt tgatataacg agtcaaagta tagatttgcc
    21721 acattactat gaccgtaatt gtgtcgctta cacagggact catgataacg aggtggttaa
    21781 cggatggtat gacaatctta gtgaagaaca agtacacttt gtaaataact atcttcacaa
    21841 acatgcagat gaaagtatta caaaagccat gctaagaaca atctttgctt ctgtttgtga
    21901 tacagccatt ctttgcatcc aagatttatt agataaagat ggtaagagtc gtatgaatat
    21961 gccaaataca attggaggta attggcaatg gcgtatgctt gacggtgaat tgaaccaaga
    22021 tcacaaagat taccttattt atttaacaga tctttatggt cgcgcaagat aatatttaaa
    22081 tgttacatta ttgaaaagag gaagacatga cacgctttac agaatatgtt gaaactaaac
    22141 taggaaaatc acttacacaa gccagcaatg aagagattta tctatcatta ttaaactttg
    22201 tcaaagaaga agctagccac aaggctaaaa attctgctaa acgcaaagtt tactatatct
    22261 cagcagagtt tttgattggt aaattactat caaacaacct gattaaccta ggaatttaca
    22321 aagacatcaa agaagaattg gcagctgctg gcaaatctac cgcagaagtc gaagatgttg
    22381 aattagaacc atcactaggg aatggtggtt taggacgttt ggcatcatgt ttcattgatt
    22441 ctattgcatc tcttgggatt aatggtgaag gggttggttt aaactatcat tgtgggttgt
    22501 ttaagcaagt cttcaaacat aatgagcaag aagctgagcc aaactactgg attgaagacc
    22561 agtcatggtt ggttcctaca aacatttcat atgatgtgcc cttcaaaaac tttaccttaa
    22621 aatctcgtct tgatcgtatt gatgttttgg gttacaaacg tgacactaaa aactacctta
    22681 atttatttga catcgaggat gttgattatg gtcttatcaa agatggcatt tcttttgata
    22741 aaacggaaat tgctaaaaac ttgaccttgt tcctctaccc agacgattct gataaaaatg
    22801 gggaattgct ccgtatttac caacagtact ttatggtgtc aaatgcagcg caattaatca
    22861 ttgatgaagc tatcgaacgt ggttctaacc ttcatgatct tgcagactac gcttacgtgc
    22921 aaattaatga cacgcatcca tcaatggtca tcccagaatt aattcgtctc ttgactgaaa
    22981 aacatggctt tgactttgat gaagcggtag ctgttgtgaa aaatatggtt ggttacacta
    23041 accacactat tcttgcagaa gcccttgaaa aatggccaac tgcttactta aacgaagtag
    23101 tgccacactt ggtaaccatc attgaaaaat tggatgctct tgttcgttca gaagtgtctg
    23161 acccagctgt tcaaattatt gacgaatcag gtcgtgtgca catggcccat atggatattc
    23221 attttgcaac aagtgtcaat ggggtagcag cactccacac agaaatcttg aaaaacagcg
    23281 aattaaaagc tttctatgac ctttacccag aaaaattcaa caacaaaacc aacgggatta
    23341 ctttccgtcg ttggctagaa tttgctaacc aagacttggc tgattacatt aaagaactta
    23401 ttggcgatga gtacttgact gacgcaacaa aactagaaaa attgatggcc tttgcagatg
    23461 acaaagctgt tcatgctaaa ttggctgaaa tcaaattcaa caacaaatta gctcttaaac
    23521 gttaccttaa agacaataaa gacattgagc ttgatgaaca ttctattatt gatacccaaa
    23581 tcaaacgttt ccacgagtac aaacgtcaac agatgaatgc tctttacgtg attcacaaat
    23641 atttggaaat taaaaaaggc aaccttccaa aacgtaaaat cactgttatc tttggaggta
    23701 aagcagcgcc tgcttacatc attgctcaag acatcattca cttgatcctt tgcttgtctg
    23761 aattgattaa caatgaccct gaagtaagcc cataccttaa tgtgcatcta gttgaaaatt
    23821 acaacgtgac agtagcagag cacttgattc cagcaactga tatttctgag caaatttcac
    23881 tagcatccaa agaagcttct ggaactggta atatgaaatt catgcttaac ggtgctttaa
    23941 cacttggtac aatggacggt gctaacgtag aaatcgctga gcttgcaggc atggaaaata
    24001 tctacacctt tggtaaagat tctgatacca tcatcaacct ttatgcaact gcttcttatg
    24061 tagcaaaaga ttactatgat aaccaccctg ctattaaagc agcagtgaac tttattatca
    24121 gtccagaatt gctagcattt ggcaacgaag aatgtcttga tcgtctttat aaagaattga
    24181 tttcaaaaga ctggttcatg accttgattg accttgaaga gtacattgaa gtgaaagaaa
    24241 aaatgttagc agactatgaa gaccaagatt tatggatgac aaaagtggtc cataacatcg
    24301 caaaagctgg attcttctca tctgaccgta ccattgagca gtataacgaa gatatttggc
    24361 attcacgata aaaaataata attgcaatgt ggggtagcgg taccgtaaca tgcttaaact
    24421 aaattataag acagtagttt ctgctgtctt atgatttttc ttcagactta ggttaattat
    24481 tacattaagc gtaaagcaag tctgtttatc gatctatgga ggtaattata agaaactaca
    24541 ctaaagtttt ttattaaaat gatataaaaa gattgatttc ggtgtacatc gaaatcaatc
    24601 tttttagcaa aatatattac gcatttttta ttcttcaagt cctacctgag acatttctgt
    24661 taactgatta ttttcaaaaa cgagagaaat attagctccg cttgtatctg tctttaagcc
    24721 actaacccaa atcgcttgca aagtttgatg atcactagat gacgcttggc tataattatc
    24781 aggttctgtt aagatctttt taacgtcttc ataagacatt cctttttgta attgttggta
    24841 ttccttttgc gataagccta actctcttgc aaaggtaaaa ttagagatgg ttttaacaat
    24901 actactattt tgataaagat taacagtgag agtaacttga tcaaactgcc aagtataagc
    24961 gtcgattgtt acttcgcctg ctgtttttgg atcatgttgg ctaggctctc caaagagtga
    25021 aataagttct tcaaggcttg ttcctcctgt aaatgaggaa tcaacagtcg caagtttaat
    25081 tttttcaaag ttagcgcgtt tatcttgatg agcggcttgg tgtagtcggg gagtaatgat
    25141 ttctgaatca gacggttgag gctctttatc tttcgttgtt gaacaagcta ccaaaaagct
    25201 agtaaaaaaa gagatgagaa gaagtgttag taagtgtttt ttgtcatatg ttatttccta
    25261 aactattttt gctgtattat atcataaatt ataaacaaga tatagctatg attccccata
    25321 acgcatgtgc tatggggaat ttagtactat tttgattctt ttttttagat attcatgaaa
    25381 aaaatggtca aaaagctctg atatgacaag gttttgagta gtattgatgg agtatcggtc
    25441 agcgtgatgg tatggctata gggataacgg aaactcatga acaagacaaa aagaaaaaac
    25501 cttgatgtaa caaggtttta gtaagttatg attacttacg gtaagcattg atggagccgg
    25561 tgggagtcga acccacgtcc aaacacctgc caacatattt gtctacgtcc ataggttatg
    25621 tcttcattta acaaactaaa gacacataac tcaagccatt agtttgcgag tctatcaatc
    25681 tcttgtcacg aaactagaca atttcgtaac cgtagcttgc tattttgaga cttctaacag
    25741 gacacaagca atcttgtaga agtcacgcta gctggttttt aggcagctaa agcgtaagag
    25801 tttgtatttt ttgcagttat atttaactgg caatttacat ctgccgatgg gacgcaaaac
    25861 atgcctcata atgcctgtcg aatccgtaac aaccccaaat agataattaa ccaatttctt
    25921 acactaacta ttctatcaaa acttttttta aatagcaaaa ttttacagct tatggtatga
    25981 ttagtctatg acaaaacgta attcaaaagc ctatatatta tggcaaaaaa ttatcaaaat
    26041 tttaggaatt attgcattaa ttggtacttt tttcctcgct ttttggctgt atagactagg
    26101 tatattaaac gatagtaatg ctcttaaaga cttagtgcag cgctatagat tatgggggcc
    26161 gtttgttttt attgtcgtgc agataataca gattgttttt cctgtgattc ctggaggcct
    26221 tacgacagtt gcaggttttt taatctttgg ccctgtaaca ggttttattt ataattatgt
    26281 aggcatcatt attggcagta tagtcctctt cttgcttgtt aagacttatg gtcgtaaatt
    26341 tatcttactc tttgtaaatg acaaaacatt ttacaagtat gaaaggcgtt tggagacacc
    26401 aggatatgaa aaattattta ttttttgtat ggcatcgcct gtttctccag ctgatattat
    26461 ggttatgatt acgggattga cggacatgtc tttaaagcgc tttgtaacta ttcttttaat
    26521 aactaaacca atttctatta tcggctacag ttatttattt atttttggaa aagatgttat
    26581 atcttggttc ttacagcatt aaggtttggt gttaatttga taaaccgctt ctatttgatg
    26641 gaagacggtt tttttattta ctatgaacac tgaaaaaaac tttcttttaa actatagtgt
    26701 gtcatagttt aaaagaaagt cttaacgctt acttactgta ggttgagttt atttttgata
    26761 ataaaattag tggcgaggta aaacattatc atttcaataa attgttccaa aataagaaga
    26821 taaattgttt tttgctcagt aaatgggaaa ctatcggcac ttgtattaat attaaagatg
    26881 tgactgtgaa catatgttgc agcaacgcta atcagaataa ctaatataaa atatgcaata
    26941 aaggccatca agcctcgccg attagaaaaa agttgaccta tagaaatgga aagataaatt
    27001 aataagatac tcgtaaatgt tgataatagg acataggcta gtacagttag catattgatg
    27061 aaataatcca tcttaaaact attaaagaat ccttctaata gttcgttgat gttaaacatt
    27121 ggtacaatta caatagcgat agcaaatgca aggatgatag tattgaaaac actgcaaata
    27181 aaagaagcta gtagttttga taaaataatt tgatgcgaat taacgggtaa agtcaacgtt
    27241 aaatatcctt cccgtccaaa aacacttttg ctaaaacgtt tgataatgat aagtaatgtt
    27301 gataagaggg aaccagcgat cagggagcca aaagttaaac ctaatgtcag aggcaacatc
    27361 ttattggtta gtactccaaa tagtccatca ctattgcttt gagcaaacag ttttatcgta
    27421 aatgacaaaa tggcagcgat ggcaataacg aaagcattaa gcgcaaagta ccattttcca
    27481 atagatctaa attcgtattt taataatttt ccaaacatga tatcctccta aaccttataa
    27541 gtttccctaa agagggaatc aatggattgc tggtattctt gtcttagatc atcagcattg
    27601 ccagataaga aaagtcttcc ttgtttcaag aaaatgactt cgtcaaggat aggttcaatg
    27661 tccgaaatca agtgggttga gataataaca gaagcatttt cacaataact attaatgatg
    27721 gtttttagga tgtagtctct tgcggcaggg tcaactccac caataggttc atcaagtaca
    27781 tagagtctgg ctttacgact catcacaaga attaattgta ctttttcttt gtttcctttg
    27841 gatagagttt tgaagcggtc ttcagggtct agttctaaat ctcttagaag gcttgttgct
    27901 ttggatttgt caaagtcgct gtaaaaatca ctaaagaact ccaacatgtc cttaattctc
    27961 atattttcat tgagataagt agtatctggt aaataagaaa taattttttt tgtctcaaca
    28021 cagggacggt agccatcaat gacaatttct cctttatttg gttgtaaaag gccattaatg
    28081 agtttaatta aagttgtttt accacttcca tttggaccta ataatccgat aattttaccg
    28141 ttcgggatag taatggttaa gtcatcaata gctttttttt cacggtaaga ttttgaaaca
    28201 tgatgtagtt gcaataggtg tgccattatt gtgaatcctc ctttaaaaag ctcgtcaaaa
    28261 cagggataat ctcagtgtga ctaaatccca tttttgtcat attggtgata aatgattcta
    28321 attcactaat tgctaactct cgtcttttac gagcaattaa tttttgatcg tcagttacaa
    28381 aacggccagc agtacgttgc gaataaacca ttccttcccg ttcaagttct gtaaacgctc
    28441 gttgcatggt gttaggattg acacctgcga tttctgcata ttcacgaaca gttggaagtt
    28501 gatcaccact cttgatttct tggctaataa tttgcatcat gacatgttgt gctatctgcg
    28561 cataaatagg agatttttca tcaaatttcc aagacatgtg gtctcctttc tgagtaatat
    28621 agatatttgt actaattaaa tggtacagaa aaaaaagggg aatgtcaagt tttatgccat
    28681 ttttcactct ttgagaagta gacgtagatt agagagaaaa ttgaagcaag aaaacctttt
    28741 tcatagtata atagggaaca agataaccaa aggaggaact tatgtttgct caacttgata
    28801 ctaaaactgt atactcattt atggatagtt taattgactt aaatcattat tttgaacgag
    28861 caaagcaatt tggttaccac accataggaa tcatggataa ggataatctt tatggtgctt
    28921 accattttat taaaggttgt caaaaaaatg gactgcagcc agttttaggt ttggaagtag
    28981 agattctcta tcaagagcgg caggtgctcc ttaacttaat cgcccagaat acacaaggct
    29041 atcatcagct tttaaaaatt tccacggcaa aaatgtctgg caagcttcat atggattacc
    29101 tctgccaaca tttggaaggg atagcggtta ttattcctag taagggttgg agcgatacat
    29161 tagtggtccc ttttgactac tatatcggtg ttgatcagta tactgattta tctcatatgg
    29221 attctaagag gcagcttata cccctaagga cagttcgtta ttttgcgcaa gatgatatgg
    29281 aaaccctgca catgttgcat gccattcgag ataacctcag tctggcagag acccctgtgg
    29341 tagaaagtga tcaagagtta acagattgtc aacaactaac caccttctat caaacacact
    29401 gccctcaagc tctacagaat ttagaagact tagtgtcagg aatctattat gatttcgata
    29461 caaatttaaa attgcctcat tttaatagag ataagtctgc caagcaagaa ttgcaagagt
    29521 tgactgaggc tggtttgaag gaaaaaggat tgtggaaaga gccttatcaa tcgcgcttac
    29581 tgcatgaatt ggtcattatt tctgacatgg gctttgatga ttattttttg attgtgtggg
    29641 atttacttcg ctttggacgc agtaaaggct attatatggg tatgggacgt ggctcggcgg
    29701 caggtagtct agtggcttat gctctgaaca ttacagggat tgatccagtt caacatgatt
    29761 tgctatttga gcgcttttta aacaaagaac gttatagcat gcctgatatt gatatcgatc
    29821 ttccagatat ttaccgttca gaatttctac ggtatgtccg aaatcgttat ggtagcgacc
    29881 attcggcgca aattgtgacc ttttcaacct ttggacctaa acaggctatt cgtgatgttt
    29941 tcaaacgatt cggggttcca gaatacgaac tgaccaatct cactaaaaaa attggtttta
    30001 aagatagctt ggctactgtc tatgaaaagt caatctcttt taggcaggtt attaatagta
    30061 gaactgaatt tcaaaaggct tttgccattg ccaagcgtat cgaaggaaat ccaagacaaa
    30121 cgtccattca tgcagctggt attgtgatga gtgatgatac cttgaccaat catattcctc
    30181 taaaatcggg cgatgacatg atgatcaccc agtatgatgc tcatgcggtc gaagctaatg
    30241 gcctgttaaa aatggatttt ttggggttaa gaaatttgac ctttgttcaa aaaatgcaag
    30301 agaaggttgc taaagactac gggtgtcaga ttgatattgc agccattgat ttagaagacc
    30361 cgcaaacgtt ggcacttttt gctaaagggg ataccaaggg aattttccaa tttgaacaaa
    30421 atggtgctat taatctttta aaacggatta agccacaacg ttttgaagaa attgttgcca
    30481 ctaccagtct aaatagacca ggggcaagtg actataccac taatttcatt aaacgaagag
    30541 aaggacaaga aaaaattgat ttgattgatc ctgtgattgc tcccatttta gagccaactt
    30601 acggtattat gctttatcaa gaacaagtta tgcagattgc acaggtttat gctggtttta
    30661 cgttaggcaa ggccgacttg ttaaggcgtg ccatgtctaa aaaaaatcta caagaaatgc
    30721 aaaaaatgga agaagacttt attgcttctg ctaagcacct agggagagct gaagaaacag
    30781 ctagaggact ttttaaacgg atggaaaaat ttgcaggtta tggttttaac cgcagccatg
    30841 cctttgccta ttcagcttta gcttttcaat tggcttattt caaagcccat tacccggctg
    30901 ttttttacga tatcatgatg aattattcta gcagtgacta tatcacagat gctctagaat
    30961 cagattttca agtagcgcaa gttaccatta atagtattcc ttacactgat aaaattgaag
    31021 ctagcaagat ttacatgggg ctgaaaaata ttaaggggtt gccaagggat tttgcttatt
    31081 ggattattga gcaaagacca tttaatagcg tagaggattt tctcactaga actccagaaa
    31141 aatatcaaaa aaaggttttc cttgagcctc tgataaaaat aggtctgttt gattgctttg
    31201 agcctaaccg taaaaaaatt atggacaatt tggatggttt actggtattt gttaatgagc
    31261 ttggttctct tttttcagat tcgtccttta gttgggtaga tacgaaagat tactcagcaa
    31321 ctgaaaaata ttctttggaa caggagatcg ttggggttgg catgagcaag catcctttaa
    31381 ttgatattgc tgagaaaagt acccaaactt ttactcccat ttcacagtta gtcaaagaaa
    31441 gcgaagcagt cgtactgatt caaatagata gcattaggat cattagaacc aaaacaagtg
    31501 ggcagcaaat ggctttttta agtgtgaatg acactaagaa aaagctcgat gtcacacttt
    31561 ttccacaaga gtatgccatt tataaagacc aattaaaaga aggagaattc tattacttaa
    31621 aaggtagaat aaaagaaaga gaccatcgac tgcagatggt gtgtcagcaa gtgcaaatgg
    31681 ctattagtca aaaatattgg ttattagttg aaaaccatca gtttgattcc caaatttctg
    31741 agattttagg tgcctttcca ggaacgactc cagttgttat tcactatcaa aaaaataagg
    31801 aaacaattgc attaactaag attcaggttc atgtaacaga gaatttaaag gaaaaacttc
    31861 gtccttttgt tctgaaaacg gtttttcgat aaaaatggac aattagtgaa gtattttgca
    31921 aatgaatgtg ctataataag accgttaaat taattaaagg agtaccagaa aatgaaacgt
    31981 attgctgttt taaccagtgg cggcgacgct cctggtatga atgctgctat tcgtgcagtc
    32041 gttcgtaaag caatttcaga aggaatggaa gtttatggta tcaaccgtgg ctatgcaggt
    32101 atggttgatg gcgacatttt cccactgggt tcaaaagaag ttggtgataa aatctcacgt
    32161 ggtggaactt tcttatactc agctcgttat ccagaatttg ctcaacttga aggtcaattg
    32221 gctggtattg agcaacttaa aaaacatggt attgagggtg ttgttgttat tggtggggat
    32281 ggttcttatc atggcgctat gcgcttgaca gagcacggct tcccagcggt aggtatccca
    32341 ggaacaatcg ataacgatat tgcgggaact gactacacta tcggatttga tacagcagtt
    32401 aacacagcag ttgaagctat tgataaactt cgtgacacct catcaagtca cggacgtact
    32461 tttgtggttg aagtgatggg tcgcaatgcg ggtgatattg ctctttgggc aggtattgct
    32521 agtggtgctg atcaaatcat tgttccagaa gaagagtttg atattgaaaa agtggcatca
    32581 acaatccaat atgattttga acacaaaggt aaaaatcacc acattatcgt cttagctgaa
    32641 ggtgttatga gcggtgaagc ttttgctcaa aaactgaaag aagctggcga taagagtgac
    32701 cttcgtgtga caaatcttgg tcacattctt cgtgggggtt caccaactgc tcgtgaccgt
    32761 gtcattgctt cttggatggg ttcacatgct gttgagctac ttaaagaagg caaaggtggt
    32821 ttggctgttg gtattcacaa tgaagaactt gttgaaagcc caatccttgg tactgcagaa
    32881 gaaggtgctt tgttcagctt gactgaagaa ggcaagatta ttgttaataa tccacacaaa
    32941 gctcgtttag actttgcagc tttgaatcgt tcattgtcac aataagttta gttaaaattg
    33001 ttaaatcgtc aattattgac aaaaaaataa gggagtttca gagtaaaatg aataaacgcg
    33061 taaaaatcgt tgcaacactt ggtcctgcgg ttgaaatccg tggtggtaaa aaatacggag
    33121 aagatggcta ctgggctggt caacttgatg ttgaagaatc agcaaaaaaa atcgctgaat
    33181 taattgaagc tggtgcgaat gttttccgtt tcaatttctc acatggtgac cacaaagaac
    33241 aaggtgaccg tatggcaact gttcgccttg cagaagaaat tgctcgtcaa aaagttggtt
    33301 tccttttgga tactaaaggt cctgaaatgc gtacggaatt gtttgcagat gatgctaaag
    33361 agtttagcta tgttactgga gaaaaaatcc gtgtagcgac tacacaaggt attcaatcaa
    33421 ctcgcgatgt tattgctttg aacgttgctg gtagccttga catctacgat gaagtagaag
    33481 taggtcatac tattcttatc gatgatggta aacttggttt gaaagtgatc gacaaagata
    33541 tcgcaacacg tcaatttatc gttgaagtag aaaacgacgg tattattgct aaacaaaaag
    33601 gtgttaatat ccctaacact aaaattcctt tcccagcact tgcggaacgc gacaatgctg
    33661 atatccgttt tggtcttgaa caaggactta actttattgc aatctcattt gttcgtacag
    33721 ccaaagacgt tgaggaagtt cgtgaaatct gtcgcgaaac tggtaacgac catgtgcaat
    33781 tatttgctaa gattgaaaac caacaaggta tcgataatct tgatgaaatc atcgaagctg
    33841 ctgatggtat catgattgca cgtggcgaca tgggtatcga agtaccattt gaaatggttc
    33901 cagttttcca aaaaatgatt atcactaaag tgaatgcagc tggtaaagca gttatcacag
    33961 caacaaacat gcttgaaaca atgactgaaa aaccacgtgc gacacgttct gaagtatctg
    34021 acgtcttcaa tgctgttatc gatggtactg atgcaacaat gctttcagga gagtcagcta
    34081 acggtaaata cccggttgaa tctgttcgta caatggcgac tattgatcgt aatgcacaaa
    34141 ctcttcttaa cgaatatggt cgtttagatt catctgcctt cccacgtacc aataaaacag
    34201 atgttattgc ttcagctgtt aaagatgcca ctcattcaat ggacatcaaa cttgttgtga
    34261 ctattactga gacaggtaat acagctcgtg cgatttctaa attccgtcca gatgcggata
    34321 tcttagctgt aacatttgat gaaaaagtac aacgtgcttt gatgattaac tggggtgtta
    34381 ttcctgttct tgctgaaaaa cctgcatcta ctgatgacat gtttgaagta gcagagcgtg
    34441 ttgctgtgga ggcaggctta gttcaatctg gggataatat tgttattgtt gctggtgttc
    34501 cagttggtac tggtggaacg aatactatgc gtgttcgtac agtaaaataa atgtgttata
    34561 actatttacc taaaggttag aaggcaagct tctaaccttt tttgatatca aaaatatcat
    34621 gttaattcac tagtgttaat ttactttaat gagtctaagt ttgtatttta tacagaatga
    34681 gcaacgttta ttggtattga tcaaaaattg tttacttttt ttctagctta gaacatggta
    34741 taataagaca atagactagg agttaatatg gtaaagcgag attttataag aaatatatta
    34801 ttgttattaa ttgtgattat tggggctatt ttgttgagaa tctttgtttt ttcaactttt
    34861 aaagtttctc cagaaacagc taatacttat ttaaagagtg gtgatttagt cacaatcaaa
    34921 aaaaatattc agcccaaata taaagatttt gtggtttata gagttggaaa aaaagattat
    34981 gtcagtcgag tcattgctgt tgaaggcgat agcgtaactt atatggatga tattttttac
    35041 ctcaataata tggtagagtc acaggcttac cttgaaaaga tgaaagcaca ttacttgaat
    35101 catgcaccgt ttggcacatt gtatacagat gattttacag ttgctaccat cacagctgat
    35161 aagtatcaaa aagttcctaa ggggaagtat cttcttttga atgataaccg gaaaaatacg
    35221 aatgacagtc gtcgatttgg gttaataaat gcctcgcaga ttaaaggttt agtgaccttt
    35281 agagttttgc ctctcagcga ttttggattt gtagaagtag agtagttgtc aggctactct
    35341 acttttttta taattagact ataccaattt tatgtttgac aagacattgt ggatattata
    35401 tactgtaaac atactgtttt tatcggtata attagactat accaattatt gaaattatga
    35461 gagaaagtag caagttaacg aacttgttaa ggtaattaag atgtgtggaa ttgttggagt
    35521 tgttggaaat cgcaatgcaa cggatatttt aatgcaaggc cttgaaaagc ttgaataccg
    35581 gggttatgat tcagcaggaa tttttgtggc taatgccaat caaacaaact tgattaaatc
    35641 agtggggcgg attgctgatt tgcgtgccaa gattggcatt gatgttgctg gttcaacagg
    35701 gattggtcac acccgttggg caacgcatgg ccaatcaaca gaggataatg cccatcctca
    35761 cacgtcacaa actggacgtt ttgtacttgt tcataatggt gtgattgaaa attaccttca
    35821 cattaaaaca gagttcctag ctggacatga ttttaagggg cagacagata ctgagattgc
    35881 agtacacttg attggaaaat ttgtggaaga agacaagttg tcagtactgg aagcttttaa
    35941 aaaagcttta agcattattg aaggttccta tgcctttgcg ttaatggata gccaagcaac
    36001 tgatactatt tatgtggcta aaaacaaatc tccattgttg attggacttg gtgaaggtta
    36061 caacatggtt tgttcagatg ccatggccat gattcgtgaa accagtgaat ttatggaaat
    36121 tcatgataag gagctagtta ttttaaccaa agataaggta actgttacag actacgatgg
    36181 taaagagctg atacgagatt cctacactgc tgaattagac ttatctgata ttggcaaagg
    36241 gacttatcct ttctatatgc tgaaagaaat tgatgagcaa ccaaccgtaa tgcgtcaatt
    36301 aatttcaact tatgcagatg aaactggtaa cgtacaggtt gatccagcta tcattacctc
    36361 tatccaagag gctgaccgtc tttatatttt agcggcaggg acttcctacc atgctggttt
    36421 tgcaacaaaa aatatgcttg agcaattgac agatacacca gttgagttgg gagtggcttc
    36481 tgagtggggt taccacatgc ctctgcttag caagaaacca atgtttattc tactaagcca
    36541 atcaggagaa accgcagata gtcgtcaagt tttagtaaag gcaaatgcta tgggcattcc
    36601 gagtttgaca gtaactaacg ttccaggatc aaccttatca cgtgaatcaa catacaccat
    36661 gttgattcat gctggacctg aaattgctgt tgcatctaca aaagcttaca ctgcacaaat
    36721 tgctgccctt gcctttttgg ctaaggcagt tggtgaggca aatggtaagc aagaagctct
    36781 tgactttaac ttggtacatg agttgtcatt ggttgcccaa tctattgagg cgactttgtc
    36841 tgaaaaagat ctcgtggcag aaaaggttca agctttgcta actactactc gtaatgcttt
    36901 ttacatcggg cgtggcaatg attattacgt tgcgatggaa gctgctttga aattaaaaga
    36961 gatttcttat attcaatgcg aaggctttgc ggctggtgaa ttgaaacatg gaaccatttc
    37021 attaattgag gaggacacgc cagtaatcgc tttaatatcg tctagtcagt tggttgcctc
    37081 tcatacgcgt ggtaatattc aagaagttgc tgcccgtggg gctcatgttt taacagttgt
    37141 ggaagaaggg cttgaccgtg agggagatga cattattgtc aataaggttc atcctttcct
    37201 agccccgatt gctatggtca ttccaactca actgattgct tactacgctt cattacaacg
    37261 tggacttgat gttgataagc cacgtaattt ggctaaagct gtaacagtag aataaatgat
    37321 tataatggat aaggcaacca tctgttaggt ggttgctttt tgtttttagg agaatagcag
    37381 agcttagaaa atggccttga gaaaagctat acaagaagaa tagtcatctt ctgatgagaa
    37441 cgtattcatc ttgtcaaatc attgattcta aagtaaaatg gtaacattaa gaaatgttta
    37501 ggagtgtaag atgtcattac caaattgttt gcaatgccag tctgaatatg tttacgaaga
    37561 tggtctttta ttaatctgtc caatgtgtgc ttttgaatgg acaccaggcg aagaagcgac
    37621 tgaagaagaa ggacttgttg ttttagatag caatggtgtc cgactgtctg atggtgatac
    37681 cattactgtg gttaaagatt tgaaagtaaa aggcgctcca aaagacctga aacaagggac
    37741 tcgtgttaaa aatattcgcc tggtggaagg tgatcataac attgattgta agattgatgg
    37801 gtttggcgcg atgaaattga aatcagaatt tgtcaagaaa atctaataat aatacgcaac
    37861 cagctgatct ggttgtattt ttataaaaaa acctctcccc aaatacgttc aaatttggta
    37921 taatagtaaa atattcagtt ttaggaggca acatgaccta tattcagcaa gttttaccca
    37981 gcttattaga tggtgccttg gtgaccttac aagtattctt tattgttatc attctttcta
    38041 tacccttagg ggctatttta gctttcttga tgaagattcc ctttaaaccg ctacagtggt
    38101 ttttgaccct atacgtgtgg atgatgcgag ggacaccatt actacttcaa ttgatttttt
    38161 tctattatgt tttgccaagt gtggggatta gttttgatcg aatgccagct gctattttgg
    38221 cgtttacttt gaattatgct gcctactttg ctgaaatttt tagaggtggg attgaggcta
    38281 ttccaaaagg tcaatatgaa gcagctaaag tattaaagtt aaaacctctt caaaccattc
    38341 gttatattat tttgcctcaa gtgtttaaaa ttgtgttacc aagtgttttc aatgaagtca
    38401 ttaatttggt caaagattct tcccttgtct atgtactcgg tgtaggagat cttttattag
    38461 caagtaagac ggcagccaat agggatgcaa ccttagcccc tatgtttatc gctggtctta
    38521 tctatttgct tttaattgga ctggtcacga ttatttcaaa acaagttgaa aaacggttta
    38581 attattatca gtaaggaggc ttcatgttag aactcaaaaa tatttccaaa cagtttggtc
    38641 aaaaaaccat ttttgatggc tttaatctaa ccgttcaaga cggagaagtg ctctctttgg
    38701 taggtccatc aggtggcggt aagacaacac tcttacggat gttggctggt cttgaatcta
    38761 ttgattcagg tcaagtcttt tacaatggag aagatgtcgg tattgatcat ttggaaaatc
    38821 gtaacttgct tggatttgtt ttccaagatt ttcaattgtt tcctcatctt accgttttag
    38881 acaacctaac gctgtctcca acaattacaa tgggcaagca aaatgttgac gctaaagaaa
    38941 aggctttgga tttactgaca cgtttaggat taaaagaaca tgcccaagtt tatccctatt
    39001 cgttatctgg aggtcaaaaa caacgggttg ctttggcgag agccatgatg attgatcctc
    39061 aaattatcgg ttacgatgaa ccgaccagtg ccctagatcc tgaattacgt cagacggtag
    39121 aagccttgat tgttcaaaac cgtgaaatgg gaataactca aattgtagtc actcacgatc
    39181 ttgtttttgc cgaagccatc tcagatcgta ttattagggt taatcctaaa tagaagagga
    39241 cccaaaagat gattataaaa aaaagaaccg tagcaatttt agccatagct agtagctttt
    39301 tcttggtagc ttgtcaagct actaaaagtc ttaaatcagg agatgcttgg ggagtttacc
    39361 aaaagcaaaa aagtattaca gttggttttg acaatacgtt tgttcctatg ggctataagg
    39421 atgaaagcgg caaatgcaaa ggttttgata ttgatttggc taaagaagtt tttcaccaat
    39481 atggactcaa ggttaacttt caagctatta attgggacat gaaagaagca gaactaaaca
    39541 atggtaaaat tgatgtaatc tggaatggtt attcaataac taaggagcgt caggataaag
    39601 ttgcctttac tgattcttac atgagaaatg aacaaattat tgttgtcaaa aaaagatctg
    39661 atattaaaac aatatcagat atgaaacata aagtgttagg agcacaatca gcttcatcag
    39721 gttatgacgc cttgttaaga actcctaaac tgctgaaaga ttttattaaa aataaagacg
    39781 ctaatcaata tgaaaccttt acacaagctt ttattgattt aaaatcagat cgtatcgatg
    39841 gaatattgat tgacaaagta tatgccaatt actatttagc aaaagaaggg caattggaga
    39901 attatcggat gatcccaacg acctttgaaa atgaagcatt ttcggttgga cttagaaaag
    39961 aagacaaaac gttgcaagca aaaattaatc gtgctttcag ggtgctttat caaagtggca
    40021 aatttcaagc tatttctgag aaatggtttg gagatgatgt tgccactgcc aatattaaat
    40081 cttaaaaagg acacttgtcc tttttttgtt taacaggtga gatctagcag acaaagtcag
    40141 ctagacgatt taataaaaa
//
LOCUS       DAUGOH010000016        36346 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUGOH010000016 DAUGOH010000000
VERSION     DAUGOH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36346
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.016"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..424
                     /locus_tag="VH957_000867"
     CDS             <1..424
                     /locus_tag="VH957_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8558789.1"
                     /translation="HMVINLINMNNIFQFGALSYGITNLFPLYVCFFFFVYISNASKI
                     TINIVEKMGIIFVISAIIGATVLAMYLTWTPVGSSTVLGVQSRYLIGIIPLVLLLFSS
                     QQQKFKQIEDILSDKLAIHISLLFILAMLMSTIFRYYH"
     gene            518..1741
                     /gene="pepT"
                     /locus_tag="VH957_000868"
     CDS             518..1741
                     /gene="pepT"
                     /locus_tag="VH957_000868"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEQ8558790.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKDRPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            1782..2270
                     /locus_tag="VH957_000869"
     CDS             1782..2270
                     /locus_tag="VH957_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEQ8558791.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(2257..2454)
                     /locus_tag="VH957_000870"
     CDS             complement(2257..2454)
                     /locus_tag="VH957_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEQ8558792.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            2503..2979
                     /locus_tag="VH957_000871"
     CDS             2503..2979
                     /locus_tag="VH957_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8558793.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            2994..3674
                     /locus_tag="VH957_000872"
     CDS             2994..3674
                     /locus_tag="VH957_000872"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEQ8558794.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    3698..3821
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            3836..4366
                     /gene="infC"
                     /locus_tag="VH957_000873"
     CDS             3836..4366
                     /gene="infC"
                     /locus_tag="VH957_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEQ8558795.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            4408..4605
                     /gene="rpmI"
                     /locus_tag="VH957_000874"
     CDS             4408..4605
                     /gene="rpmI"
                     /locus_tag="VH957_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEQ8558796.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            4664..5023
                     /gene="rplT"
                     /locus_tag="VH957_000875"
     CDS             4664..5023
                     /gene="rplT"
                     /locus_tag="VH957_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEQ8558797.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(5314..7524)
                     /locus_tag="VH957_000876"
     CDS             complement(5314..7524)
                     /locus_tag="VH957_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEQ8558798.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTKNRE"
     gene            7632..8795
                     /locus_tag="VH957_000877"
     CDS             7632..8795
                     /locus_tag="VH957_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEQ8558799.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            8792..9478
                     /locus_tag="VH957_000878"
     CDS             8792..9478
                     /locus_tag="VH957_000878"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEQ8558800.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVALNDMKRI
                     IEVLEMDISN"
     gene            9572..10738
                     /gene="aroC"
                     /locus_tag="VH957_000879"
     CDS             9572..10738
                     /gene="aroC"
                     /locus_tag="VH957_000879"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEQ8558801.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            10799..11140
                     /locus_tag="VH957_000880"
     CDS             10799..11140
                     /locus_tag="VH957_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEQ8558802.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADVSASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            11361..12713
                     /gene="gorA"
                     /locus_tag="VH957_000881"
     CDS             11361..12713
                     /gene="gorA"
                     /locus_tag="VH957_000881"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEQ8558803.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKAIVDVLVEEM
                     AVGGPCLHPHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(12801..14069)
                     /locus_tag="VH957_000882"
     CDS             complement(12801..14069)
                     /locus_tag="VH957_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8558804.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(14099..14539)
                     /locus_tag="VH957_000883"
     CDS             complement(14099..14539)
                     /locus_tag="VH957_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558805.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITITRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTTPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTNP"
     gene            14774..15916
                     /locus_tag="VH957_000884"
     CDS             14774..15916
                     /locus_tag="VH957_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8558806.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPVRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     VYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            15928..17142
                     /gene="thiI"
                     /locus_tag="VH957_000885"
     CDS             15928..17142
                     /gene="thiI"
                     /locus_tag="VH957_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEQ8558807.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVYLNGTDYQPVVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQSFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            17180..18472
                     /locus_tag="VH957_000886"
     CDS             17180..18472
                     /locus_tag="VH957_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEQ8558808.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    18577..18651
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            18686..19000
                     /gene="rplU"
                     /locus_tag="VH957_000887"
     CDS             18686..19000
                     /gene="rplU"
                     /locus_tag="VH957_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEQ8558809.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            19012..19338
                     /locus_tag="VH957_000888"
     CDS             19012..19338
                     /locus_tag="VH957_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEQ8558810.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            19366..19659
                     /gene="rpmA"
                     /locus_tag="VH957_000889"
     CDS             19366..19659
                     /gene="rpmA"
                     /locus_tag="VH957_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEQ8558811.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            20017..20931
                     /locus_tag="VH957_000890"
     CDS             20017..20931
                     /locus_tag="VH957_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8558812.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            20928..21386
                     /locus_tag="VH957_000891"
     CDS             20928..21386
                     /locus_tag="VH957_000891"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEQ8558813.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            21376..22266
                     /locus_tag="VH957_000892"
     CDS             21376..22266
                     /locus_tag="VH957_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8558814.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDTLAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGYGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            22661..23182
                     /gene="pyrR"
                     /locus_tag="VH957_000893"
     CDS             22661..23182
                     /gene="pyrR"
                     /locus_tag="VH957_000893"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEQ8558815.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            23198..24457
                     /locus_tag="VH957_000894"
     CDS             23198..24457
                     /locus_tag="VH957_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEQ8558816.1"
                     /translation="MKDIIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            24518..25453
                     /locus_tag="VH957_000895"
     CDS             24518..25453
                     /locus_tag="VH957_000895"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEQ8558817.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            25497..26579
                     /gene="carA"
                     /locus_tag="VH957_000896"
     CDS             25497..26579
                     /gene="carA"
                     /locus_tag="VH957_000896"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEQ8558818.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            26825..30001
                     /gene="carB"
                     /locus_tag="VH957_000897"
     CDS             26825..30001
                     /gene="carB"
                     /locus_tag="VH957_000897"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEQ8558819.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLTIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            30176..31447
                     /locus_tag="VH957_000898"
     CDS             30176..31447
                     /locus_tag="VH957_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8558820.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGVGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVTVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            31447..32157
                     /locus_tag="VH957_000899"
     CDS             31447..32157
                     /locus_tag="VH957_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8558821.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            32169..33389
                     /locus_tag="VH957_000900"
     CDS             32169..33389
                     /locus_tag="VH957_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8558822.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGKGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            33643..35376
                     /locus_tag="VH957_000901"
     CDS             33643..35376
                     /locus_tag="VH957_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEQ8558823.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            35503..35775
                     /gene="rpsP"
                     /locus_tag="VH957_000902"
     CDS             35503..35775
                     /gene="rpsP"
                     /locus_tag="VH957_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEQ8558824.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            35785..36024
                     /locus_tag="VH957_000903"
     CDS             35785..36024
                     /locus_tag="VH957_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEQ8558825.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
BASE COUNT        11499 a         6028 c         7566 g        11253 t
ORIGIN      
        1 acatatggta attaatctga ttaatatgaa taatattttt cagtttggcg cattaagcta
       61 tggtataacg aaccttttcc cgctttatgt gtgtttcttc ttttttgttt atattagtaa
      121 tgctagtaaa ataactatta atattgtaga aaaaatgggt ataatctttg ttatttcagc
      181 gattataggt gcaactgtat tagctatgta cctgacttgg acaccagtag ggtcctcaac
      241 tgtattaggt gttcaaagtc gttatctgat aggaattatc ccattagtgt tgcttctttt
      301 tagtagtcaa cagcaaaagt tcaaacaaat agaggatatc ctttctgaca aactggctat
      361 tcatatttcg cttttgttta ttctcgcaat gttaatgagt actattttta gatattatca
      421 ttaaactctt aattagaggc tttaaaaaac ttagcttgaa taagtatttt aaagcctttt
      481 atgctataat taaattgaga aattattgag gtggcctatg aagtacgata acttgttaga
      541 tcgatttata aaatatgtca aagtgaatac aagaagcgat ccagacagtg agactactcc
      601 tagtacggag agtcaagaag catttgcctt aacgatttta aagcctgaaa tggaggcaat
      661 tggtttacaa gatgttcatt ataatccagt taatggctat cttattggaa ctctgcctgc
      721 caataatcca accttgacgc gtaaaattgg ttttatagcc catatggata cggctgattt
      781 caatgctgaa aatgttaatc cgcagattat tgacaattat caaggagggg acattacact
      841 tggcagttct aattataagt tggatccaaa agcatttcca aatcttaata attatatcgg
      901 tcaaacattg attaccactg atgggactac acttttaggg gcagatgata aatctggtat
      961 tgctgaaatc atgacagcaa tagaattctt aacatcacaa ccacaaatag agcactgtga
     1021 cattaaagtg gcttttggcc ctgatgaaga gattggggtc ggagctgata agtttgaggt
     1081 ggctgatttt gaggtggatt ttgcttatac tatggatggc ggtcctttag gcgaattgca
     1141 atatgaaact ttcagcgctg cagctctaga agtgactttt ttaggcagaa atgttcatcc
     1201 tggtacggct aaggatcaaa tgattaatgc ccttcagtta gcaatagatt ttcatgagaa
     1261 gctacctgct aaagatcggc ctgaatacac agatggttat caaggtttct atcacttaac
     1321 gggactaact ggaacagttg aagaggcacg cgcatcttac attattcgtg attttgaaga
     1381 agcatcattt gaagctagaa aagtgaaagt tgaaaatata gctcaatcga tgaatgctca
     1441 gctaggaaca aaacgtgtct tggtagagct taatgaccaa tactacaata tgaaaaaagt
     1501 tatcgaaaaa gatatgaccg ctattgagtt agctaaagaa gtaatggaag agcttgctat
     1561 caagcctgta atcgaaccca tacgtggagg aacagatggc tctaaaattt catttatggg
     1621 tattcccact cctaatattt ttgcaggggg tgagaatatg cacgggcgtt ttgagtttgt
     1681 tagcttacaa acgatggaga gagctgtcga tgtcattatt ggacttgttt gcaaagccta
     1741 attatcatgg aattgatatt tagtggaagg ggcttataaa aatgattaaa ctatttggta
     1801 aaataaggta tcactggcag ccagagttgt cttggtctat tatttattgg tctattgcgt
     1861 ttgcacctat ttttgtaggt ttatctttgt tgtatgagcg cactgaaata cctagtcggg
     1921 tttttattct atttgctatt tttgctgtcc tagttggcat tggattacat cgttatttca
     1981 ttattgaaaa taatggtatt ttaagaatcg tatcttttaa attgtttggt ccacgtaagc
     2041 tacttatttc cactattact aagattgagg tgaccaaatc aacactttgt ctgcacgttg
     2101 aagataaaag ttatctcttt tatatgcgca aatggcctaa aaaatatttt cttgatgcct
     2161 tagcggttaa tccatacttc caaggagaag ttatattaag tgataacttt attaaattag
     2221 actattttga agtttatcag catgataaaa aagcccttac tcgagggtaa gagctttagt
     2281 tgggcaagat ttgacagcta aaatagcgtc cttatctgaa ggacaaattg actgacttgt
     2341 ttcagatgag cttgaaaatg tgacgatacc attgtcatga taatcaaaaa gtgatgaata
     2401 ggtttggcat agaccacaag cgatgcattt ttctggaatg atagatactt tcataactat
     2461 tattctaata tgattttgtt aaattaacaa ggggggacga tcatggctaa agaaccatgg
     2521 gaagaaaaaa ttgttgatga tactataggg acacgaacac gtaaatcaag aaatgctttc
     2581 attagcacgc cttggttgac tgctttatta agtgtattct ttgtcatcat tgttgctata
     2641 ctttttattt tcttctatac atcaaatagc ggtagtaata gacaagctga aacaaatggt
     2701 ttttatggag catccactca taaaaaaaca aggaaagctt ctaacgctaa aaaaacatca
     2761 agtagttcaa caactacaga cacaacacct tctagcgaag aaacacttgc ttctagtgaa
     2821 ggaactggcg aaacccttac tgtattggca ggtgaggggg cagcttctat tgcagctcgt
     2881 gcaggtattt ctgtggagca gttacaagca cttaatccag agcacatgac tcaaggatat
     2941 tggtatgcca atccaggaga tcaagtcact attaaataat tgaagaggaa aaaatgaaag
     3001 caattaaaat tgcgattgat gggccagctt caagtggaaa aagtacagta gccaagatta
     3061 ttgcaaaaaa tcttggctat acttatctag atactggtgc tatgtatcgc tcagcaactt
     3121 atatcgcact gacacatggc tatacgggta aagaagtagc ccttatttta gaggaacttg
     3181 agaaaaatcc tatttccttt aaaaaagcaa aagatggctc ccaattagtt tttcttgggg
     3241 atgaggacgt gaccttagcc attaggcaaa atgatgtgac taacaatgtt tcttgggtct
     3301 cagctttgcc agaaattaga gaagagctgg ttcatcaaca aagacgcatt gcacaagctg
     3361 gtggcattat catggatggt cgtgacattg gaacggttgt tctcccagat gcggaactaa
     3421 aaatcttttt agtggcttct gtcgaagagc gggcagagcg ccgctataaa gaaaacctag
     3481 aaaaaggaat tgaatcagat tttgagacgc taaaagaaga gattgcagct cgtgattaca
     3541 aggatagtca tcgtaaggtt tcacctctaa aagcagctga agatgccctt atttttgata
     3601 ccacaggtgt ttctattgat ggcgtggtgc aatttatcca agaaaaagca gaaaaaatag
     3661 ttgacatgtc ctagagccta tgttagaata gtaacaatga gaaaagtaga agtgagagct
     3721 tctcgccttg cgacttaggt tgtctggccc taacatgtca aattcctatg gaatattata
     3781 tgtgcgggct tgatttatca agtccgcttt cgtttttctc taaaaaaata aagaggtgaa
     3841 gatcatagct aaaaaggatc tattcattaa tgatgaaatt cgcgttcgcg aagttcgtct
     3901 cgttggtctt gaaggtgaac aattaggtat taaaccattg tctgaagcgc aatcattggc
     3961 tgatgcttca aatgttgatt tggttttaat ccagccacaa gctgttcctc ctgttgccaa
     4021 acttatggac tatggaaagt tcaaatttga gtatcaaaag aaacagaaag aacaacgtaa
     4081 aaaacaaagc gttgtgactg tgaaagaagt tcgtctcagt ccagttatcg ataaaggtga
     4141 ctttgaaaca aaacttcgta acggtcgtaa attccttgaa aaaggaaata aagttaaggt
     4201 ttctattcgt ttcaaaggac gtatgattac tcataaagag attggtgcca aggtactagc
     4261 tgactttgct gaagcgactc aagatattgc tatcattgag caacgagcaa aaatggatgg
     4321 acgccaaatg tttatgcaac ttgcaccaat ttcagacaag aagtaattgt cacagtttca
     4381 ttatatcttt aagaggagaa tactaaaatg ccaaaacaaa aaacacaccg cgcatcagct
     4441 aaacgtttta aacgtacagg ttcaggcggt ttgaaacgct tccgcgcctt tacatcacac
     4501 cgtttccacg gaaaaactaa aaaacaacgt cgtcatcttc gtaaagctgg tttggttagc
     4561 tcaggagatt tcaaacgtat caaagcaatg gttactggtc tttaatttta aaggcagtag
     4621 acatttacga gtattataag aattatttga aggagaacta ttaatggcac gtgttaaagg
     4681 tggcgttgtt tcacgcaaac gtcgtaaacg tattttaaaa ttagctaaag gttactatgg
     4741 agcaaaacac atcttgttcc gtactgcaaa agagcaagtg atgaactctt actactatgc
     4801 ataccgtgat cgccgtcaga aaaaacgtga tttccgtaaa ctatggatca ctcgtatcaa
     4861 tgcggctgct cgtatgaacg gtttgtcata ctcacaattg atgcacggtt tgaaacttgc
     4921 tgaaatcgaa gtaaaccgta aaatgcttgc tgatttagca gtagctgatg cagcagcttt
     4981 cacagctctt gctgatgcag ccaaagcaaa acttggcaaa taagaaacgc tatacctaaa
     5041 aaataacttt ctattaccta tagaaagtta taaagaaaca aaaatgaagg agacgatgga
     5101 cgtcttcttt ttattatact caatataata aaaagaagtt tcccatgttt tattaccagt
     5161 aatgtgggat atttagatgg tagcaagaag ttttatagtt gatttgtttt ctttaggtct
     5221 aattagcata ttttgattac tgataaactt gaatatcgcc aataaaaaag aagcaaaatt
     5281 attattttgc ttctagtcag atcattaaat tgattattct ctatttttgg tgttatcctc
     5341 ttttagttca gaagttgccg cgtcagcttc tacgggattt agttctaagt aagatggtgc
     5401 tttaaaaagt ttctgagttg atttatgacc atttttactg tataaacttg ttgactctga
     5461 tccgagtttt gctgaaatat ctttcagttg ttttaactgc ttagtgtaga taaactggtt
     5521 aggatcaata gcttttagac cattttgagt atcaaagcgc aggagatcac ccgtttgaat
     5581 agcgtcgcta gctgctagtt gttgagcaac agcagagcga atttccttag ttttggctat
     5641 agtcatttca tcgggattag tgatttctaa acctgtttgc gtgttgtaca gacgtccact
     5701 atagttagtg tattcaggag tcatataagt cccagatgtt cgttgtgcca caatctggct
     5761 attttgaggt gataataaat cttgtcctaa ttgaacaaac tgactagtgt caataccaag
     5821 tatgtggagt aaagtaggaa gagcatcgat ttcaccgcca aaggtttctt tgatactacc
     5881 attcgtataa cctggaatat ggatcatata cgggactcgt tgtagcatag cattatcata
     5941 ttcagaccaa gtttcagaat ctttaccaag aagtggagca agactagaat tacgagaatt
     6001 tgaaatacca taatggtcac catataaaac aaaaatagaa ttgtcgtaca aaccagtggc
     6061 tttcaagtaa tcaaaaaaag atttaagggc agcgtctaaa taattggcag tagcaaagta
     6121 accattgatc gtttcatcgt ctgttttggc taaaggaaaa ccttcttcac tactttcgcc
     6181 ttttagacta gtataaggat agtgattact cacagtgata aacttggtat aaaaaggttg
     6241 ttgcatctgt tcaagatatt ttatggaatc cttaaacatg tacttatcat ttaacccata
     6301 ttgaaaagag ttcttactat tttgtttaga gaagtagcta gaatcaaaaa aataattata
     6361 gccccattgt ttataagcat tattgcgatt ccagaaagtt ccaacgttac catgaaagac
     6421 agcgctggta tagccacctt tttgggctaa aatacttgga gtagcaaatt gtgtattttc
     6481 accaccgtag ttcaccataa aagaaccact atttaaacca aataaggaat tctccatcat
     6541 ggtttcagca tcagaagttt tacctgcttt aacctgatga aaaaagttag ggaatgctaa
     6601 ggtagcattt gagtgataaa gcgagttgat aaaaggcgtt acctcatatt ctttatctcc
     6661 ttcttttagt ttataatcta ttaagaattg ttgaaagctt tctaaatgaa gaacaataat
     6721 atttttgcct tttccaattc caaaatactg gggatcaggt gctgcataat gtcctttgac
     6781 ataagtttta acatcaatta attcttctgc agtagctcca tttcgttctt tttgagcttg
     6841 ataggtttga ttgccgctat agagggtaaa cgctggtaat cctaaagctc tcacaatata
     6901 agtatttgaa aagccacgtg ttaatagttc cggacgatca atttctgcta aaaaaagatt
     6961 aatagaaagc aatagactag ataaagcggt gatggcaaat gctgcgcgct tgttaaaagg
     7021 acgttgatca tttttgattt ttttagtgat agataaacta attagaataa taaaatcaag
     7081 aatatagata atatcccaga tgcgtaaaag gtttaaagca gagtccccta atccagcgga
     7141 gactttactg ctagctagca tggcactcac tgtaataaag tctgaaaatt ctcggtaata
     7201 tatagaattt gatatcaaga gaatgttaag gataatataa accacccaag aacagatata
     7261 aaaggctcgg gtattcttaa cgtaaagagc gacccccaaa agtaaaaaag ctagtgggat
     7321 tggattgata attgttagaa agacttggta tatatttccc aaatctagtg aaaagtctgt
     7381 atgatatgcc cacagagtct ttatccagta acaaaagagt agagtaatta taaaacccaa
     7441 tcttgtgttg ataaaacctg tgataagtgt tttaaatttc ttcacagtag caacttcctt
     7501 atcgtttttt cctaaagatg tcatctccaa ataaaatctc agattaaatt ataccaaaaa
     7561 tgtgaagcta atgcttgttg taagttcaaa tttagtagga ttttttatca gattttgtta
     7621 taataaaaac tatgaataaa ctctatattg attcttttgt cgaaaagaag ctgacagcag
     7681 gggtacaatt attagatgaa aaagattttt ctaatataaa ggaaaaaaat cagttggttc
     7741 aactggtgac caagtccaat cgtcccattg gaacagcata tatctctaag caaaataaag
     7801 gaattggttg gtatctagga ccagaaaaaa tcgacttgtc tatctcttat tttgttagtc
     7861 tattttcagt tgctaaggcc aaaagacaag attttgctca atcggacgag accaatgctt
     7921 atcgcctttt taatcaagaa ggagacggtt ttggtggagt aacaattgat ctttataaag
     7981 attttgcagt cttttcatgg tacaatgcct ttgtctatga caaaaaagaa atgattatgg
     8041 aggcttttca acaggttttt cctgaagtca aaggagctta tgaaaagtgt cgctttaaag
     8101 gtccagatac tgaaactgct catctgtatg gtgagctggc acaagaaacc ttttcgattt
     8161 tagaaaatgg catagcctat caagtcttct tgaatgaggg cttaatgaca ggtatttttc
     8221 tagaccagca tgatgttaga agagcactag tagatggttt agctatgggc aagtcccttc
     8281 ttaacctatt ttcctataca gctgcctttt ctgtagcagc tgcgatgggt ggtgctatcg
     8341 agaccacttc tgtggacttg gctaaacgat cgagagaatt atcactagct cattttgagc
     8401 ataaccagtt aaacttagcc tcacatcatt ttgtggtgat ggatgttttt gaatacttca
     8461 aatatgccaa acggaaaaaa ttaatctttg atgtgattgt gattgaccca ccaagctttg
     8521 ctagaaataa aaaacaaact ttctctgtga gcagggacta ccacaaatta atcacagagg
     8581 ccttggacat attgagtcct aagggaacta ttatagcttc aacaaatgct gctaatatga
     8641 ctgttagcca gttcaaaaag caaattatca aaggatttgg aagtcgtcgt cctgagtcta
     8701 tgactctcca gcagcttccg agtgacttta ctatcaataa agcagatgaa agaagtaact
     8761 atttaaaggt atttactata aaggtacgag aatgagaatt gtagcaccag tcatgccaag
     8821 acattttgac gaggctcaag ccattgatat ttctaaatat gaagatgtta atttaattga
     8881 atggcgagca gactttcttc ccaaggatga gattgtcgca gtagcaccag ctatttttga
     8941 aaaatttgcc ggaaaagaaa ttatctttac ccttcggacc gttcaagaag gggggaatat
     9001 taccctttca agtcaggagt atgttgatat tatcaaagaa atcaatgcta tttataatcc
     9061 agactatatt gactttgagt attttacgca caagtcagta tttcaagaaa tgcttgattt
     9121 tccaaatctt attttgtctt atcacaactt tgaagagact cctgaaaatt taatggaagc
     9181 tttttcagaa atgaccaagt tggcaccgcg tgtggttaaa attgctgtga tgccccagag
     9241 tgaacaagat gttctagatc tgatgaacta taccagaggc tttaagacgc tcaatcctga
     9301 gcaagaattt gcaactatat ctatggggaa attaggaaga ttgtctcgtt ttgcgggaga
     9361 tgtcattggc tcttcctgga catacgtttc attagatcat gttagcggtc caggtcaagt
     9421 ggctctcaat gatatgaaac gtattattga ggtcttagaa atggatatct ctaactagtg
     9481 aatggtctaa aaatattatt tctacaatag ttaagaaatg atgtttttag attaatgttt
     9541 ttaaaataag tggaaccaaa aaggagaaaa attgcgttat ttaacagcag gagaatctca
     9601 tgggccatcc ttaacagcta ttattgaagg tataccagca ggattaactc ttcatccagc
     9661 ggatattgat cacgaattac agcgacgtca aggaggttat ggccgtggtg ccagaatgtc
     9721 tattgagact gatcgggttc aaatatcctc aggagttcgt catggcaaaa caacaggggc
     9781 ccccattacc ttaacggtaa ttaataagga ccaccaaaaa tggctagatg tcatggctgt
     9841 aggagacatt gaagagactc tcaagttaaa gcgtcgtgtt aagcatccta gaccaggaca
     9901 tgcggatttg gtaggaggta ttaaatatca ttttaacgat ttaagagatg ctttagagcg
     9961 ctcctcggct agagaaacaa cgatgagagt ggctgtaggc gctgttgcta aacgtatctt
    10021 agctgaactt ggaattgata tgttacatca tatcttaata tttggtggta taacgatcac
    10081 aataccttct aagctctctt ttagagagct gcaagaaagg gctctccatt cagaattatc
    10141 tattgttaat ccaaagcaag aagaagaaat taaaacgtat attgataaga taaaaaaaga
    10201 aggggatacc attggtggta ttatcgaaac gatagttcaa ggggtgccag caggtcttgg
    10261 atcttatgtc caatgggata aaaaattaga tgccaagctg gctcaagcag ttctttccat
    10321 taatgctttt aaaggggtgg aatttggagt tgggtttgat atgggattcc aaaagggctc
    10381 tcaggtaatg gatgaaatca cctggacacc tacccagggc tatggtcgtc aaacaaacca
    10441 cttaggtggc tttgaaggtg gcatgaccac aggacaacct cttgttgtta aaggggttat
    10501 gaagcccatt cctactttgt ataaaccact catgtcggta gatattgata gtcatgaacc
    10561 ttataaagca acggtggaac gctctgatcc gacggcctta ccagctgcag gggttatcat
    10621 ggaaaatgtg gtggcgacgg tgcttgccaa agagatttta gagacttttt cttctactac
    10681 catgtctgaa ttgcaaaaag ctttttcgga ctatcgtgcc tacgtcaagc aattttagat
    10741 agcgagatac tggcttttat ggtatcatac aggtattaat gaacaaaagg agactgtcat
    10801 gtcacaagaa atttatgact atgctaatca acttgaaaga gcagttcgtg ctctgccaga
    10861 ataccaaaaa gtgttagaag taaaagaggc cattcaagca gacgttagtg ctagcgaact
    10921 gtttgatgag tttgtcgcta tgcaagaaaa aatccaaggg atgatgcaat caggccaaat
    10981 gccaacggct gaagaacaaa caagcattca agaacttagc caaaagattg aagctaatga
    11041 ccagctaaaa gcttattttg aagcgcagca ggccttatct gtttacatga gtgatattga
    11101 gcgtattgta tttgctccgt tgaaagattt agtcaagtaa gccaattaag ataggaaaaa
    11161 aacagattgc tggcagctcg tcaggatctg ttttttagtg tttattttct ttgtatcaga
    11221 aagttgagcc tctttcttat ttgtgatata gtcaaataaa gtgaccaaaa tagcaggcca
    11281 gtagtggctt taatgaaggc aagttgtctg ctaactggct atgctaaaac atcagtatta
    11341 gaaagtaaaa ggtgataaaa atggttattc cttatgatta tattgttatt ggtggaggga
    11401 gtgcaggtat tgcttctgcg aacagggcag ccatgcatgg ggccaaagta ttgttagctg
    11461 aaggtaaaga gattggggga acctgtgtta acctaggctg cgttcctaaa aaagtcatgt
    11521 ggtatggcgc tcaagtagca gatattttag ggacttacgc taaggattat ggatttgact
    11581 ttaaagagaa agcatttgat tttaaacaat tgaaagcaaa tcgtcaagct tatattgatc
    11641 ggattcatgc ttcttatgag cgaggctttg agcagaatgg tgttgaccgt atttatgatt
    11701 atgctgtttt caaagatgct catacggtag aaattgcagg gcagctttat accgcaccgc
    11761 atattttgat tgccacagga ggacatcctg tttttccaga tattgagggg gcacaatacg
    11821 gtatcagctc ggacggcttt tttgccttag atgaggtacc aaaacgtacg gctgtggttg
    11881 gggcaggcta tattgctgtg gaacttgccg gtgttttgca tgctttgggg tcgaagacgg
    11941 atttgtttat ccgtcacgat cgacctttaa gaagttttga caaagccatt gtggatgttt
    12001 tagttgagga aatggcagtt ggtggtcctt gcttacaccc tcattcagaa gtggcaaagg
    12061 ttgtcaaaaa tactgatgag tccttgaccc tttacctcaa agatggccaa gaagttgagg
    12121 ttgaccagct catttgggct atcggtcgca agcctaatct agaaggtttt agtcttgaca
    12181 aaactggagt gacgttaaat gataaaggtt atattgagac agatgcctat gaaaacacgt
    12241 ctgtcaaagg tatttatgcc gtgggagatg ttaatgggaa actggcttta actccagttg
    12301 ctgtggcagc tggacgtcgc ctatcagagc gtcttttcaa tggcaaaaca gacgagaaat
    12361 tggactacca gaacgttgct actgtgattt ttagtcaccc tgttattggc tctgttggct
    12421 tgtcagaaga agcagcagtc aaacagtatg ggcaagaagc agttaaaaca tatcaatcac
    12481 gttttacgtc tatgtttact gctatcacta accatcgcca accttgtctg atgaagttgg
    12541 taacagtcgg agataccgaa aaaatagttg gtcttcacgg aatcggatac ggggttgacg
    12601 aaatgattca gggctttgca gtagccatca aaatgggagc aaccaaggcg gattttgata
    12661 acaccgttgc tattcaccca actggctcag aagaatttgt caccatgcgc taaaaaatgt
    12721 agcctaaggc aataaaaaat gatgttaaca gtttttgagg aaagtcttct aaactgctag
    12781 catcgttttt tgttaggtga ttaggggaat atgtttttaa agatatttgc gttgctcaga
    12841 caatattgcc ttacctcgga gataaaataa agtgaccctg taacaacaaa gagttcatca
    12901 gatgttacgg aaccttgtaa ccagtctctg taatctttta cctgtgggta tttatcagga
    12961 taatcctcta aaagatttgc ttcagggaaa tcaaaagtcg tgacagatac ttcaaaagta
    13021 tctagttgag ccagcaagtc ggctaaaggc ttacgtttga gacctgcaaa gagaatatga
    13081 ataggacgtt tgggaaattc ttcttgcagt agagacttta atttagcaat ggaatctgga
    13141 ttgtgagcgc cgtctaatag aagattaggt tgaataaatt cggaccggcc aggccaagtt
    13201 gttgcctcaa ttcctttttg aatcgttttt ggagatattt taggaaagga ttttctaagt
    13261 aattgagctg tcataatggc taaacaggca ttcgcttttt gatgttgacc taatagtttg
    13321 agacggagtt tggttaaatt caagttatcg tgttgaaagg aaaacgtctt ttctgaagga
    13381 ttgagcaaaa aatcttttcc taattgatat aagcgtgaac cggctttttg ggtaacttgt
    13441 tgaaagactt gactagcctc ctgctcaagt tgaccgataa taacgggttc tttagctttg
    13501 ataacttctg ctttttggtg agcaatttct gctaggctat aacctaaacg ttcttggtga
    13561 tcaaaactaa tggaagggca tacgacggcc agagcatgaa aaacattggt tgcgtcggtt
    13621 ttcccaccaa tccctgcctc aataatggca atatcaacag gtttaagatt ggcaaagtag
    13681 caaaacatta tgagagtcac taactcaaac tcggtaggtc tatcccaatt tgtttcaagg
    13741 gacattttag tgagaatggg tctaatcacg ctcacacatt gcgccaattc taggtctgaa
    13801 atgggctggc cattaaggca gatccgatcg tgaaaagaga tgataaaagg agatgtaaag
    13861 gttccgacct gataaccaga agttgacagg atatgctgta agtaggctgt cacagagccc
    13921 ttgccgttag ttccaacaac gtgaatagca gggaatttgt cttgtggccg gcctagtgcc
    13981 tcaagtaacc aagccattct ggccaaatcg gtcttgcgac cattagcctt aaaggtatga
    14041 atccaggaaa tgctatcata ggtagtcatt actatttctt gtccttctaa caatgcttct
    14101 aagggttcgt aggaagacca gtattagcat cttcagctcc agttgcatta ggaagttgcg
    14161 tcccttcagt ggttgatggt gtctcagggg ctgtaggagt tgtctcgttg tgagaaggtg
    14221 tggtagaaga tgacggaaga gttgtcttat tatcatctgt ggtttctgaa gtacctgtat
    14281 ggttttgatt accctgagaa gactcttttt caataatctt gacaatggta ttactcgatt
    14341 ctttgggtgt atcattagag gtcttatctg gtacaggctg cagtgctctt gtaatggtaa
    14401 tggttgccac aatgatactc aaaatactac caataagtgc aatggatttt tggaaagctg
    14461 taaaacctgt tttaatatgc tcggtaggga cacctcctga tttacgaggt ttttgttgac
    14521 gggaataacg tgatgacata tttttctcct ttaaaatcat cgtaatgcca agattaagga
    14581 ggaggaaaca gaagtcctag ctcctcttta acacttcatc tatcagtata atctagaaaa
    14641 aaagtgaagt caacggttta ccttatgtct aggacaagga agtcctttgg gcttattgta
    14701 atacgaatat tcttgatttc attttagcta ttttgtgata gaataaagta ttgagtaaaa
    14761 atgaaggtga cacatgattt attttgataa tgcagccaca accatacctt atggagaggc
    14821 tcttaaaact taccaagaag tagcaacaaa aatatatggc aatccctcaa gtctgcacca
    14881 attagggaca aatgcgtctc gcattttaga agcttcccgt aaacagattg ctggtttgtt
    14941 gggtgttaag tcagaagaaa tcttttttac gtctggtggg actgaaagtg ctaattgggc
    15001 tattaaggga attgcttttg aaaaaaccgc ttttggcaaa catattatta tctcagccat
    15061 tgaacaccct gccgtgagtg aaagtgtcaa atggcttctc acacaaggat tcgaagtttc
    15121 ttatgctcca gtgacaacac agggagttgt tgatgtgaat gctttagctg agctgattag
    15181 accagacacc atcttaatct cgattatggc tgttaataat gaaatgggag ctatccaacc
    15241 ggttagagcc atttcaaacc tattggctaa ccaaccaacg atcacctttc acgttgatgc
    15301 tgttcaagcc attggtaaaa taccactctg tgattatatg actaatcgtg tggatttggc
    15361 ttctttttca gggcacaaat ttcatagtgt tcgtggtgtt ggcttccttt ataaaaaagc
    15421 aggcaagcga ctcaatcctc tcttgtcagg cggcggccaa gagcaggagt tacgttcaac
    15481 cactgaaaat gttgcaggaa ttgctagcat ggccaaagca ttaagaatag tcactgaaaa
    15541 acaagtgagc gtcttaccta aactaacagc aatgcgagat gtgatttaca aagctttgtc
    15601 cgtttaccca gatgtgacag tattttcagc tcaagaaggc tttgcgccca atattttgac
    15661 ctttgggatt agaggggttc gaggagaagt tattgtccac gcctttgaaa aatatgagat
    15721 ttatatttcg accacaagtg catgttcgtc caaagcaggt aagccagcag gaagcctagt
    15781 ggctatgggg attcctgtaa aaactgccca gacagccgtt cgtattagtc tagacgatga
    15841 caacgatatg ggacaagtag agcaattttt gaccatattc aaacagattt atgataaaac
    15901 acagaaagtt aggtaagatt aggtaagatg gactattcag aaattatggt tcgccatggt
    15961 gaactatcaa ctaaagggaa gaatcgcatg cgattcatta acaaacttaa aaacaatatt
    16021 caagacgtac tggctccttt cccagccatt actgtccgtt cagatcgtga cagaactcat
    16081 gtctatttga atggcacaga ttaccagcca gttgtagaag ctttaaagct ggtgtttggt
    16141 gttcaagctc tatctcctgt ttataaactt gaaaaaagtg tccctctttt ggtaacagct
    16201 gttcaagata tcatgacttc tctttatcgt gatggactga cgtttaagat tgccactaag
    16261 cgtagtgatc atgcgtttga attggatagt cgtgagctta acagtcttct tggtggagct
    16321 gtttttgagg ttttaccaaa tatccaagcc cagatgaaac atcccgatgt gactctcaaa
    16381 gtcgaaattc gtgatgaagc agcttacatt tcttatgaag agattaaggg agcaggcggg
    16441 ttaccagtag gaacgtcagg gaaagggatg ctgatgttat cgggcggtat tgattcacca
    16501 gtagctgggt atttagccct taaacgtggc cttgatattg aagttgttca ttttgctagc
    16561 cctccgtaca ccagtccagg tgccttggct aaagcccaag accttactcg tcggttaact
    16621 cgttttggtg gaaatatcca atttatcgag gttcctttta cagaaattca agaagaaatt
    16681 aaaaataagg caccagaggc ttaccttatg acattaaccc gccgctttat gatgcgcatc
    16741 acagatgcca ttcgtgagca acgtaagggt cttgttattg ttaacggtga gagcctaggt
    16801 caggttgcta gtcaaaccct tgaaagcatg caggccatta atgcggtaac atcgacccca
    16861 attattagac cagtcgtgac aatggataaa cttgaaatta tcgagatggc tcaggcgatt
    16921 gatacttttg acatttctat tcaatcgttc gaagattgct gtactatttt tgcaccagac
    16981 cgtcctaaaa ccaatcctaa actaggtaat gctgaaaaat atgaagaacg ctttgatatt
    17041 gatggtcttg tccagcgtgc tgtgtcagga attgttgtca cagaaatcac acctgaaatc
    17101 gtcaatgatg aggttgaaaa tctcattgat gctttacttt aaaagaaaag atcaagtgta
    17161 aatcttttag tagtcagtaa tgatactatt aaaaagcctc tataagggct tttttgctgc
    17221 aatgaaggag gaaaattttg aggcaagatg ttataataga gaaaaaggag ggtgtgtctt
    17281 gattaaaact atgcaataca aaaaaacgat ggcaacagtt gttgctctta tcgtcgcact
    17341 tttgctattt ggcttgattt atgatttact tggggttcaa aaaaatgagc tagcagctca
    17401 aaaatctgct cagccaaagg tcaaaacagc acgtgttgta gctaatggcg acattttaat
    17461 tcatgatatt ctctacatga gtgctagaaa agctgacgat acctatgatt tcactcctta
    17521 ttttgaatat gttaaggact ggattagcgg tgctgactta gctattggag attatgaagg
    17581 gaccattagc ccagattatc ccttagcagg ctatccctta ttcaatgctc cagaagagat
    17641 tgcaggtgct ctgaaaaata ctggctatga tgtagtcgat ttagcccata atcatatctt
    17701 agattcccaa ttagacggtg cccttaacac taaaaaggtt tttcatcaat taggtataga
    17761 cagtattggc atctatgaca aggatcgttc aaaagaatcc ttcttaatta aaaatgtcaa
    17821 tggtatcaaa attgcaattt taggttattc ttatggttat aacggcatgg aggccacact
    17881 tagccaagaa gactatgaga aacacatgtc tgatttagat gaagctaaga taaaaaaaga
    17941 acttcagcta gctgaaaaaa aggctgacgt gaccattgtc atgccacaaa tgggaacaga
    18001 atatgcctta gaaccgacag cagagcaaaa agaactttac cacaaaatga ttgattgggg
    18061 agctgacgtc gtcctaggag gccatccgca tgttattgaa ccttcagaga cagttataaa
    18121 aggtaggcaa aagaaattca ttatttactc tatgggaaat tttatttcaa atcagcggct
    18181 tgaaaccgta gatgatatct ggactgagcg tggcctattg atggacctta cttttgagaa
    18241 aaaagataac aaaacaaaaa ttaaaacagt tgaggcccat ccaaccatgg ttttagccaa
    18301 aggtaaaggc attgtgggta aagaaggttt tgaactatac aattatcgaa caatggtttt
    18361 agaagatttt atcaaaggtg gaaaatacca cgacaagatt gatgaggaaa ccaaagcaaa
    18421 agtagcactt gcttatcagg aaattaatga tttagttaac ctgaaatggt aatgtttggt
    18481 ggtttagcat ctaacgataa aaaatagaga ttaaacttaa tttttccttg ataaaaagca
    18541 gttatggtgc taaaatagta acgttgacta aatgcacatc ctgtgcaacc gcgcgaaaat
    18601 cgttatcaag tagaccaagt ctcacgattc caggcgagtc ttcacagagg gaaacctcaa
    18661 acaaaaattt tataggaggt gcatcatgag cacatacgca atcatcaaaa ctggtggaaa
    18721 acaagttaaa gttgaagtag gtcaagcaat ctacgttgag aaaattgacg ctgaagctgg
    18781 cgcagaagtc acttttaacg aagttgttct tgtaggtggt gacaaaactg tagttggtac
    18841 tccagttgtt gaaggagcta ctgtcgttgg aactgttgaa aaacaaggaa aacaaaagaa
    18901 agttgtaaca ttcaaataca aacctaaaaa aggtagccac cgtaaacaag gtcatcgtca
    18961 accttacact aaagttgtca tcaacgcaat caacgcttaa tttactagct tatgattaaa
    19021 gcaattttta ctcgccaaaa aaatggtcaa ctgagcagtg ttacactgac aggtcatgct
    19081 ggtagtggta aacatggctt tgatattgtt tgtgcctctg ttagtactct agccattaac
    19141 tttgttaatt ctcttgaggt gttagcagat tgccaagcat tagtagatct taatgatgtt
    19201 gaaggtgggt atatggctat tacaatacca ccacatgaca acaaggagga agttcaatta
    19261 ttatttgaat cttttcttct aggaatgact agtttggcga aggattcttc gaaatttgtc
    19321 aacactcagg tcatctaaat ttaatttaag agaggaaaca acattatgtt aaaaatgaat
    19381 cttgctaact tgcaactttt cgcccacaaa aaaggtggag gttctacatc aaacggacgt
    19441 gactcacaag ctaaacgcct tggtgctaaa gctgctgacg gtcaaactgt ttcaggtgga
    19501 tcaatccttt accgtcaacg tggaactcat atctacccag gtgtaaacgt aggccgtggt
    19561 ggagatgaca cactttttgc taaagttgaa ggtgttgtac gtttcgaacg taaaggacgt
    19621 gataaaaaac aagtttctgt ttacccagta gctaaataat tgtttaacat cgcattatat
    19681 aaggctttcc aggtgtctgg aaagccgatt tttttatttt ggtactcatg ttgctaccca
    19741 tattttaaaa atcaatgtag gaagagagct tgtcagcagt tttatctttt gaggatttag
    19801 taacatgagc gtagatgttc atggtagttt ggatagtttc atgaccaagt gtattggatt
    19861 ttcattgttt gtttctatcc tactaaagat tgtagttgct tatttagagc aatagttcta
    19921 attgtaaaaa gtcagcataa taaaacaatg tcataagatg ttgttataac gggctttatg
    19981 gtataattaa ggatactcat tttaggaagg aaagcaatga atattcaaca attacgctat
    20041 gtggtagcca tcgctaataa tggaactttt cgagaagctg cctctaaatt gtttgtcagt
    20101 cagcctagct tatcagtttc tatcaaagat ttagaggcgg aattagggtt tcaaattttt
    20161 aatcgaacta cttcaggaac agtcttgaca agtcaaggac tagtttttta tgagaaagct
    20221 ttagaagtag tcaaatcttt tgattctttt gaaaaaacct tttctcaagc tgatctggat
    20281 caaaatgaat tttctattgc tagccaacat tatgactttt tgccacctct tattacagct
    20341 ttttcgcaac aatacgatgg tcatcgtgtc tttcgtatct ttgaatcaac aactattcaa
    20401 attttagatg aggttgctca aggaaacagt gaaattggta ttatttactt gaatgtagac
    20461 aatcaaaaag gcctctttca gcggatggat aagctgggct tggaatatgt ttctctaatt
    20521 ccttttacta ctcatattta tctttcaaaa acgcatccat tggctaatcg cgaagcgctt
    20581 tatttgagcg atattcaagg attacctgcg gtaaggttta cccaagaaag ggacgagtat
    20641 ttgtattatt ctgaaaattt tgtggatact agtgaatgcc ctcgtattta taatgtgtca
    20701 gatagggcaa ccttgaacgg tattttagag agaaccaatg cctttgcgac aggatcaggt
    20761 tttctcgatc atcggagtgt taatgggatt aaagtgatac ctctagctga tcatattgac
    20821 aatcaaatga tttatgtcaa acgaaaagat aaaaaccttt ctgttgctgg ggccactttt
    20881 gtgactattt taaaagacta ttttgataaa agaaggaagg ccttaacatg aaaaaacgat
    20941 tgtttgtgct tagcttgatc ctccttgtag ctttggatca acttagtaaa ttttggattg
    21001 tttctcatat agcgcttgga gaagtgaaac cctttatccc aggtatcgtc agcttgactt
    21061 acttgcaaaa caatggggct gccttttcca tattgcagga ccagcaatgg ttctttgttg
    21121 tcataacggt tttagttatc ggttatgcta tttattacct tgctactcat ccccatttaa
    21181 atatctggaa acaattagct ctcttgctta ttatttctgg tggaatcggg aattttattg
    21241 atcgtttgcg tttagcttac gtgattgata tggttcattt agactttgtg gattttgcca
    21301 tttttaatgt ggcagattca taccttaccg ttggtgtcat attattagtg atatgtttat
    21361 ggaaagaaga ggattatgga aattaatgtg ataacatcgg ggcaacgctt ggataaggca
    21421 ctagctgatt taagtcccct gtcacgtggt caagccaatg accaaattaa gcaaggcctt
    21481 gttttagtta atggtcagca aaaaaaggct aaatatacgg ttcaagcagg agatgtgatt
    21541 tgttttgaac tccctaaaga agaagtctta gagtaccaag ctcagaatat tcccttggac
    21601 attatctatg aagatgatac tctcgccatt attaacaagc cacagggaat ggtagttcac
    21661 ccttcggcgg gacacccttc aggaacaatg gttaatgcct tgatgtatca tatcaaggat
    21721 ttgtcctcaa tcaatggtgt ggttcgtcca ggaattgttc atcggattga taaggacacc
    21781 tcaggtctct taatggtagc taaaacagat gcagctcatc aagccttggc agaagaatta
    21841 aaggctaaaa aatctctcag aaaatacctc gccattgtcc atggaaacct accgaatgat
    21901 cgcgggatga ttgaagctcc tataggtcgt agcgaaaagg accgtaaaaa acaggctgtt
    21961 acagcaaaag gcaaagaagc agtgacacgt tttacagtgc tagaacgttt tggcgattac
    22021 agtctagtgg aattacaact ggaaactggt cgaacgcacc aaattcgtgt tcatatggcc
    22081 tatattggtc atcctgttgc tggggaccct ttatatggac cacgtaagac actatcaggt
    22141 tatggccaat ttcttcatgc aaaaacattg ggattaacgc atcctatgac aggaaaagaa
    22201 atgatattta ctgttgaagc tcccgaaatt tttcaaaagg tgttaaagct gctaagaaaa
    22261 aaataaacag cgaggagtag ccattatttt tagtcttata tctttgtgta aagtttttaa
    22321 cattataaaa aatactaaaa agcatttacg ataagccagg aaatatgaga agtcttttat
    22381 gttattggga tatgcaacat atctgttaga gatctttatt taaactctta aagaaaagag
    22441 atattccaaa tagatgctag gtattgtctt ttttacttgt ttttcttttc tttttttgct
    22501 atactgattg aaataaaata ttcctttaaa acagtcctgt gaggctgtca aggagacgga
    22561 ttaaaaacat gcactatgat acttaattgt gctatatttt gctgaatctc cttgtttcca
    22621 aggagatctt tttatttgaa tttttagagg aggtttcaac atgaaaacta aggaaattgt
    22681 tgatgacgtg accatgaaac gcgccattac ccgtattact tatgaaatta ttgaacgtaa
    22741 taaacaatta gacaatgtgg ttttggcagg catcaaaacg agaggtgttt ttctagctcg
    22801 tcgcattcaa gaaagactgc atcaattaga agggttggat ttaccaattg gtgagttaga
    22861 catcaagcct tttagagatg acatgagagt tgaggaagac acaactctga tgtcagtaga
    22921 tattacaggc aaggatgtga ttttgattga tgatgtgctt tatactggtc gtaccatccg
    22981 cgcggccatc gataacttag tgagtttagg tcgaccagcc cgtgttagtc tagctgtttt
    23041 ggtggatcgt ggccatcggg aattaccgat tcgcgcggat tacgttggga aaaatattcc
    23101 aacaagcagt gtagaagaaa ttgttgttga ggttgtcgaa gttgatggcc gtgatcgtgt
    23161 tagcattatt gacccaacat aagaaggagg ttttactgtg aaagatatca tttatgatgt
    23221 ggaagaagtg ccaaaggcag gtatgttagt tggtttgtcc tttcagcatt tatttgccat
    23281 gtttggggcg acggttcttg ttcctatttt agttggaatt gacccgtctg tggccctcct
    23341 atcgagtggt ttaggaacac ttgcacattt atcggtaacc aaatttaaaa ttccagccta
    23401 catgggctca agttttgctt atatagcagc tatgcagtta ctgatgaaga caaatggtat
    23461 tggtgctgta gctcaagggg ctatgacagg aggtctcgtt tacctgattg tagctttgat
    23521 tgttaaagct attggcaatg attggattga taacatctta ccaccgattg tggttggtcc
    23581 gattgttatg gtcattggtc taagcctagc ttctacagct gttaatgatg tcatgctaaa
    23641 aaatgggaac tataatctga cttatcttgt tattgggtta gtcaccttat tatcagttat
    23701 ttttttcaat atttatggta agggaattgt tgctattgta ccgcttttat tagggctatt
    23761 agttggttat gttgtagccc ttttagtggg tgttctcacc ggtcaagaaa ttgttgattt
    23821 taccaatgtg gctcaggcca aatggtttag tatcccatca gtggaaattc ctttcttaac
    23881 ctacggggtt aaattctacc caagtgccat tttaactatg gcacccattg cctttgttac
    23941 aatgacagaa cattttggac acattatggt cttaaatagt ttgacaaaaa gagattattt
    24001 caaggatcca ggacttgaaa agactttaac tggtgatggt tttgcgcaaa tcattgccgg
    24061 cttcttaggg gcacctccgg tcacttctta tggtgaaaac atcggtgtaa tggctttgaa
    24121 taaaatattc tcggtttatg ttattgcagg tgccgcagtg attgccgctc tcctcagttt
    24181 tatcggtaag gtatcagcct taattcaatc tattccaaca ccagttattg gaggtatatc
    24241 agttgccttg tttggtgtaa tagcttctag cggtttgaaa atcttgattg aatccaaagt
    24301 tgatatggat aataagaaaa acttattgat tgccagtgtt attttggtct ctgggattgg
    24361 aggattgatg cttcaagtaa atggtcttca aatttcaggt gtcgctttct caacacttct
    24421 tggcatcatc ttatatcagg tacttcctga aaaataggaa gaattgttgt tagaccactt
    24481 acatagtcat cagtcgttag tgataaaggg gataatcatg tcagttgtaa ataatcgcgt
    24541 tgcacttacc aatttagttt caatggaagc attaaccacc gaagaagttt taggtcttat
    24601 caaccgtggt tcagaatata aggctggtaa ggttgttatt tcggatcatc aaaaggatct
    24661 tgttgccaat ttattctttg aaaactccac ccgaacccat aagtcttttg aagtggctga
    24721 gaagaaactc ggcttgacag ttcttgattt caatgctgat gcaagtgcgg ttaacaaggg
    24781 agaaagtttg tatgatactg tgttaaccat gagtgcactt ggaacagaca tctgtgtgat
    24841 tcgtcaccca gaagatgatt attacaagga attagtagaa agtccaacta ttacagcttc
    24901 cattgtcaat ggaggagatg gttctggaca acacccgagt caatgtttac ttgacttatt
    24961 aaccatctat gaagaatttg gacgctttga aggcttaaag attgcgatcg ctggtgactt
    25021 aactcactct agggtggcaa agtccaacat gcaaatcctc aaaagattag gagcagagct
    25081 ttatttctat ggacctgaag aatggtattc agaagccttt aatgcttacg gcacttatat
    25141 tgctattgac cagattatta aggaattgga tgttcttatg ttgctgcgtg tacagcacga
    25201 acgtcatgac ggccatcaga gtttttcaaa agaaggttac catcaagcgt ttggattgac
    25261 acaggaacgt taccaacaat taaaagattc tgctattatt atgcatccag ctccagttaa
    25321 tcgggatgtg gaaattgcag atagtttggt ggaagctcct aaagcgagaa ttgtatctca
    25381 gatggctaat ggtgtctttg ttcgcatggc tattattgaa gccattttga atggtagaaa
    25441 taaaaactca tgatgaaaga ttaaagcatg tttagaaggt aggaaaaggt aggaaaatga
    25501 caaaacgatt acttatttta gaagacggca ctatttttga aggagaaccc tttggtgctg
    25561 atattgatgt gactggtgaa attgtcttta atacaggaat gacaggctac caagaatcca
    25621 tcactgacca atcctacaat gggcaaattt taacctttac ctatcctttg attggaaatt
    25681 atgggattaa tcgagatgac tatgagtcca tttcacccac ctgtaaaggg gttgttgtgt
    25741 ctgaagtcag tcggttggca agtaattggc gcaagcaaat gacgctagat gcgttcttga
    25801 aaataaaagg gattccaggg atttcgggaa ttgatacgag agctttgacc aaaattattc
    25861 ggcaacacgg taccatgaaa gctacgatgg cagatgatgg agatagtatc cagcatttaa
    25921 aagatcaact gcgtgcaaca gtcttaccga ctaacaccat tgaacaagtg tcaactaaaa
    25981 cagcttatcc tgcaccaggg atcgggaaaa atattgtatt ggttgatttt ggtttaaaac
    26041 attctatttt aagagaattt tctaaaagac aatgtaatat caccgttgtc cctttcaaca
    26101 tcactgcaga agaagtgctc caactaaatc cggatggctt gatgctatct aatggcccag
    26161 gaaacccaga agatttgcca gaggctttag acatgattcg tggggtacaa ggtaagattc
    26221 ctatttttgg tatttgtatg ggacatcaac tctttagtct agcaaatggt gccaagactt
    26281 gtaaaatgac ctttggtcat cgtggcttta accatgccgt tagagaaatt gcaacgggaa
    26341 gaattgattt taccagtcaa aaccatggtt atgccgttga acgtagtagt ctacctgata
    26401 ctttaatggt tacgcatgaa gacattaacg ataagacggt cgaaggagtg aaacatagag
    26461 attttccagc tttttcagtc caatttcacc ctgatgcggc tccaggacct catgatgcca
    26521 gctacttatt tgacgaattt ttggaaatga ttgattcttg gagatgtacg agtaaatagt
    26581 aaatcagttg caatttcacg actatatcac ctcttgttac tctatttatt aacatttaca
    26641 gttgatttag taccctatca aaaatattat ttaatgttgc tctgtgaggc aacaaataga
    26701 gaaaggaagg caaggagaac acaagtaaat aatttagtaa aaagttaggt tttcaaagag
    26761 ataaagctct tattgagaag tgctgacttt accgcttctt gtggtattct tggtatcatt
    26821 aattatgcca aaacgaaaag atattcaaaa aatcatggtt atcgggtctg gcccgattat
    26881 tattggacaa gctgctgaat ttgattatgc agggactcag gcctgtttgg ctctaaaaga
    26941 agaaggctat aaggtcatac ttgttaattc aaatcctgca acgattatga cagataaaga
    27001 aatcgctgat aaggtatata ttgagccttt gactcttgaa tttgttaatc gtatcattcg
    27061 aaaagaaagg ccagatgcca tactgccaac cttaggtggt caaacgggcc tcaatatggc
    27121 aatggcatta tctaaagctg gtattcttga tgatttagag attgaattgt taggtactaa
    27181 gttatctgcg attgatcagg cagaagacag agaccttttc aaacaattaa tgcaagaact
    27241 agaccaaccc attccagaat ctacaattgt taaaacagtt gatgaagctg ttacatttgc
    27301 tagagatatc ggttatccag tcattgtgcg cccagctttt actcttggtg gaactggtgg
    27361 aggaatatgt agtagtgaag aagaactttg tgaaattact gaaaacggcc taaagttatc
    27421 accggtcaca cagtgtttga ttgaacgctc aattgctggc ttcaaagaaa ttgaatacga
    27481 agtaatgcga gatagtgctg ataacgcgct ggttgtttgt aatatggaaa actttgatcc
    27541 cgtagggatt cacacaggag attctattgt atttgcacca acacagaccc tttctgatat
    27601 tgaaaatcaa atgttacgtg atgctagttt aaaaataatt cgagctctga aaattgaagg
    27661 tggctgtaac gtccagttag cactagatcc ttatagtttc aaatattatg ttattgaagt
    27721 aaatcctaga gtgtctcgtt cctctgccct tgcttcaaaa gcaacaggtt atcccattgc
    27781 caaattggct gcaaagattg ctgttggcct aacacttgat gaaatgatta accctatcac
    27841 aggcactact tacgctatgt ttgaacctgc ccttgattac gttgttgcta aaattccgcg
    27901 ttttccgttt gataaatttg aacatggtga acgccaactg ggaactcaaa tgaaagcgac
    27961 aggtgaagtc atggctattg gccgtaattt ggaagagtcc ttactaaaag cctgtcgttc
    28021 tttagaaatt ggtgtttgcc ataatgagat gacaagttta agtaacatta gcgatgaaga
    28081 gttagtgact aaagtgatta aagctcaaga tgatcgactt ttttacttgt cagaagcaat
    28141 acgacgaggt tatagtatcg aagaacttga gagcttgacc aagattgatt tatttttctt
    28201 ggataaatta cttcatattg ttgaaataga gcaagaatta caaatgcatg ttgaccattt
    28261 ggaaagcctc aaaaaagcaa agcgttatgg attttcagat caaaaaattg cagaaatttg
    28321 gcaaaaggat gaaagtgata tcagagcgat gagacattct catagcctgt atcctgtcta
    28381 taaaatggta gatacttgtg cagctgaatt tgatgctaaa accccttatt tttattcaac
    28441 atatgagttg gaaaatgaat ctgttcagtc gaataaagaa tcaattttag ttttaggttc
    28501 aggccctatt cgtattggtc aaggggttga atttgactac gcaacggttc attctgttaa
    28561 agccatccaa aaagctggct atgaagccat tatcatgaat tcaaatccgg agactgtatc
    28621 tacagatttt tcggtatcag ataaattata ttttgaaccg ttaacctttg aagacgtcat
    28681 gaatgtgata gatttagagc agcctaaggg agtaatagtt cagtttggag gacaaactgc
    28741 tattaactta gcacaagcac tttctgaggc gggtgttaca atattaggaa cacaagtaga
    28801 ggatttggat agggctgaag acagagattt atttgaaaag gcgttgaaag agcttggaat
    28861 cccgcaacca caaggtcaaa cggcaactaa tgaagaagaa gctttagagg cagctaaaaa
    28921 aattggtttt ccagtcttag ttagaccttc ttacgtactt ggtggccggg ctatggaaat
    28981 tgttgaaaac aaagaagatc ttagagaata tataagaaca gcggttaaag caagtcctga
    29041 acatcctatc ttagtggact cttatatttt cggtaaggag tgtgaagtgg atgccatttc
    29101 agatggaaaa tcagtcttaa ttcctggtat tatggagcac atcgaaagag caggtgttca
    29161 ttcaggagat tcaatggcag tttatccgcc acagcaatta tctaagcaaa ttcaagaaac
    29221 aatagctgag tatactaaac gtttaaccat tgggttaaat tgtattggta tgatgaatgt
    29281 tcaatttgtt attaaaaatg aacaagtcta tgttattgaa gtgaatccac gcgctagtcg
    29341 taccgtgcct ttcttatcaa aagtaacagg tattccgatg gctcagattg ctactaagtt
    29401 gattttaggt caaacattaa aggatctagg atatgaagat ggtctttatc cccaaagtca
    29461 actggtgcat atcaaagcgc ctgtgttttc atttacaaag ttggcacagg ttgatagtct
    29521 tttaggtcct gaaatgaaat caactggaga agtaatgggt tcggatacta gtcttgaaaa
    29581 agcactttat aaagcgtttg aagccaataa ttctcattta tcagaatttg gtcaaattgt
    29641 ctttactata gcagatgata gtaaggcaga agctctaagt ctagcaagac gatttaaggc
    29701 gattggctat caaattatgg ctactcaagg tacagcagct tactttgctg agcaaggctt
    29761 aagcgcgtgt ttagttggaa aaattggtga tgctgccaat gacatcccga cactcgtgcg
    29821 acatggtcac gttcaggcaa ttgttaatac agttggaatt aaacgcacag ctgataaaga
    29881 cggacagatg attagaagtt cagctattga acaaggagtt cctttattta cagctttaga
    29941 tactgcaaaa gctatgttaa cggttttaga aagcagatgt tttaacatcg aagcgatata
    30001 aaaatgattt ttttagatta taatgacaaa agtttcagta agctattaat ttgtcatagc
    30061 atataagtca ttatcttgtg gcttgttttc gactaagggc taagaatttc ttgacaacaa
    30121 tataaaaagg tcatatactt gtcttataca aatagtacaa aaggggagga tagaaatgtc
    30181 taaaagagga aaaattaaaa taacaacgaa aacaaagctt attacagcta gtgttataac
    30241 gctagtatta attataactg gagtagtctt gtggaaacaa caacaaaata cgctaacagc
    30301 tgatatcgct aaagaacctt actctactgt tagtgtaact gaagggagta ttgcttcttc
    30361 gactttacta tcaggtactg taaaggcttt atcagaggaa tatatttatt ttgatgctaa
    30421 taaaggaaat gatgcaactg ttacagttaa agtaggtgat caggtaacgc agggccagca
    30481 attagttcaa tataatacaa caacagctca gtcagcttat gatactgctg ttaggagtct
    30541 taacaagatt ggccgacaaa ttaatcatct taaaacatac ggagttcctg ctgttagtac
    30601 agaaactaat aaagatgaag ctaccggtga agagacgaca acaacagttc aaccatcagc
    30661 tcagcaaaat gctaattata aacagcagct gcaagattta aatgatgctt atgcagatgc
    30721 acaagcagaa gtaaataaag cgcagatagc gttaaatgat acagtagtta tcagtagtgt
    30781 ctctggaact gttgtggaag taaataatga tattgatcct tcttcaaaga acagtcaaac
    30841 acttgttcac gtagcaaccg aaggacagct tcaggtgaaa ggaacattga cagagtatga
    30901 tttagcaaac gttaaggttg gtcaatctgt aaaaattaag tctaaagttt attctaatca
    30961 agaatggact ggaaaaatat catatgtttc aaactatcca actgagtcta atgcaggttc
    31021 aacaacgcca gcaggtagca ctggagtggg aagttctaca ggagctgcct atgattacaa
    31081 gattgatatt ataagtcctc ttaaccagct taaacaaggt ttcactgttt ctgttgaggt
    31141 tgttaatgaa gctaaacagg ccttagttcc tttaacggct gttattaaga aagataaaaa
    31201 acactatgtt tggacttatg atgatgctac tggcaaagcc aaaaaagtag aggtgacact
    31261 tggaaacgca gatgcacaac aacaagaaat tcataaagga gtaactgttg gtgacattgt
    31321 tattgccaat ccagataaaa atatcaaacc ggataaaaaa ctagaagggg ttatttcaat
    31381 aggtaccaac acaaaaccgg aaaaagattc tcaatcaaag aataaaaaat caggggtgga
    31441 taaatagtgt cgcatgaaaa aaaacaatta atgcaattat caaatattgt gaagagctat
    31501 caaaatgggg atcaagttct taaagttttg aaaggtatta atttaacagt atatgagggt
    31561 gaatttttag ctattatggg tccgtctggt tcgggaaaat caacactaat gaatattatt
    31621 ggtttattag atcgtccaac atccggagat tacacattac ataatactaa aatagaaatc
    31681 cttaatgatc gtgaattagc aaaagtacga aatgatgaaa tcggctttgt ctttcaacaa
    31741 ttctttctgt tagctaaatt aactgcatta caaaatgttg agttgcctct tatttatgct
    31801 ggtgtaaacg tctcaaaaag acgtgaacag gctaagcaat ttcttgaaaa agtaggactt
    31861 ggacgacgta tcaaacatct accgtcagaa ctgtcaggag gtcaaaagca aagggtggct
    31921 atcgcacgag ctttagtaaa tgacccatct attattttag cggatgaacc aacaggtgca
    31981 ctagatacta aaacaggtca gcaaattatg gaactcttga cagagttaaa caaagaaggt
    32041 aaaacaatta ttatggttac tcatgaacca gaaattgctg attttgcaac tcggaaaatt
    32101 attattcgtg atggtgatat cacaacggat actacagcta gtgttgttat tgactaggag
    32161 gaaaaataat ggaaaattgg aaattcgctc ttagctcaat ttgggggcat aagatgcgct
    32221 caatcctgac aatgttggga attatcatcg gtgtagcagc agttgtgatt attatggggt
    32281 tgggaaatgc tatgaaaaat agtgtaacaa gcacattttc tagcaagcaa aaagatattc
    32341 aactctattt tcaagaaaaa ggagaagaag aagacctgta tgccggattg cacacgcatg
    32401 aaaataatca cgaagtgaag ccagagtggt tagaacaaat tgttaaagat atcgatggta
    32461 ttgattctta ttactttacc aattctgcta cttctactat ttcgtatgaa aaaaagaaag
    32521 tagacaatgc ttcgatcata ggggtaagta aagattattt taatataaaa aactatgata
    32581 tcgtagctgg tcgtacacta acagataatg attattctaa tttttcgcgt atcattcttt
    32641 tagatacagt attagccgat gacctatttg gcaaaggtaa ttataagtca gctttaaata
    32701 aagtggtaag tttatctgat aaagattatt tagttattgg tgtttataaa actgatcaga
    32761 cgccagtttc ttttgatgga ttatcaggcg gcgctgtcat ggcgaatact caggtagctt
    32821 cagagtttgg caccaaagaa ataggatcta tctacattca tgtgaacgat attcaaaaca
    32881 gtatgaactt aggaaatcaa gcagctgata tgctaaccaa catatcgcat attaaagatg
    32941 gacagtacgc tgtccctgat aatagcaaaa tcgttgaaga aatcaatagt cagttcagta
    33001 tcatgacaac agtcataggt tcaattgcag cgatctctct tttagtggga ggaattggtg
    33061 ttatgaatat tatgttggta tctgtcacag agcgaactag agaaattggt ttacgtaaag
    33121 cacttggtgc aacacgcctg aaaattttat cacaattttt gattgaatcc gttgttctaa
    33181 cagttcttgg aggcttgata ggattattat tagctcaatt aagtgtaggg gctttaggaa
    33241 atgcgatgac attaaaagga gcttgtattt ctcttgatgt ggccttaata gcagttttat
    33301 tttctgcctc aataggtgtc ttttttggaa tgttgccagc taataaagct agtaagttag
    33361 atccaattga ggcattacgt tatgaataga atagttcgta tcaattaatc tatagacgct
    33421 gactagttta acgtctgatt atatctagtt tttgtattag cacagtagtt atatcattga
    33481 agtgttagtg cattttttga ggtgataata tctagcaaag ctatcattgg tatgatgatg
    33541 tggatagcgt ataagtgata catctcttat ttctagctga acttcggttc ggctaggaag
    33601 ttgtcaggca atgagttgtt taaaataaag gagattagtt caatgacatt tttatctgat
    33661 ttgatatcat taatgacaaa aatcagatta tcttgggtaa taaaggcggg tatttttcaa
    33721 ttattatttg taacgattgc taatattgtc ttatcagaat ttttctattt tatattagac
    33781 gttactggtc aatatcattt agataaagac aatgttgtga cttttttaaa aaatcctata
    33841 gcacttgctt tattaggtgc ctatttattt ttattagctg cttttattca ccttgagttt
    33901 tttgctctat atcgaattat tgcggatcaa gaaattagtt tctatctttt tagaaaacag
    33961 ttttcttatt acctaagggg gctttggaaa acattttctg gttaccaatt attacttttt
    34021 ttgctttata tcctactgac tattccagtc ttacatattg gtttatcttc tgtgattact
    34081 caaaagcttt atcttccaga atttattgtt ggggaattat caaagataac tagcacaaag
    34141 tacttgcttt atggcagtct tattcttgtg ttttacctta acctaagatt agtatatttt
    34201 ttaccattga tagcaatcaa ccatcgtacg gttgctcaag catggagaga gagttggcaa
    34261 aagactaaaa agaaacatgt attgttatgg atgaaacttt ttgcaatcaa tggtcttacg
    34321 cttgtagtct tatcgctagc tatttccatg attcttattt ttgttgatat gtttaatcct
    34381 aaggggaata atattattgt tcagctggga gctttgacct ttacatggga gctcattttt
    34441 tttactacta ttttttttaa actctgttca gcaatgattt taaaagaggc aattgaacca
    34501 caaaagcaat atgatgagcc aagaagaagt aataaggcat atgttgtaat ctttatcgtg
    34561 gtgacagtag gttttgctta tcaatctctt gaacgtttaa ctttttttga cacatctcac
    34621 tctaagacag ttatcgcgca tagaggactt gtatcagcag gtgtagaaaa ttcactggaa
    34681 gcccttgaag gtgctaagaa agcaggaagt gattatgtag aactggatct aatcttgact
    34741 aaggataatc actttgtggt gtctcatgat aatcgattga agcgtttagc tggagtaaat
    34801 aagacgattc gcaacttaac cttaaaagaa gttgaacatc taacgagtca tcaaggacat
    34861 ttttcagggc gttttgtttc ttttgacact ttttatcaaa aggctaagaa gttgaatatg
    34921 ccattactta ttgaactcaa gccaattggt acagaacctg gaaattatgt cgatttgttt
    34981 ttagaaactt atcatcgact tggtataagc aaagataata aagtcatgtc tttagattta
    35041 gaagtaatag aagctatcaa gaaaaaaaat ccatcaatta cgactggtta tatcatacca
    35101 attcaatttg gcttttttgg agatgaattt gttgatttct atgtcattga agacttttct
    35161 tatcggtctt atttgtcgtc ccaagctttt tggaataata aagaaattta cgtttggact
    35221 attaatgatc ccaagcgcat agagcattat ctcttaaagc ctattcaggg aattattaca
    35281 gatcaaccag ctttaactaa tcaattgatt aaagacttaa aacaagataa ttcttatttt
    35341 agtcgattag tcagaattat tagtagtctt tattaaaggt ttaaagaaag tgtcaagaaa
    35401 aaaacttgac actttcttta aactgagtta tactgtttaa cataggaatt tagcgtagct
    35461 gtatttctta tacattacta aaagaaaaga gactatttaa aaatggcagt aaaaatccgt
    35521 ttaactcgta tgggttctaa gaaaaaacct ttctaccgta ttaatgttgc agattcacgt
    35581 gcaccacgtg atggtcgttt tatcgaaaca gttggaacat acaacccatt agtggctgaa
    35641 aatcaaatta ctattaaaga ggatcgtgtt cttgagtggt tatctaaagg agcgcagcct
    35701 tctgataccg ttcgtaacat cttgtctaaa gctggtgtta tggctaagtt ccacgaccaa
    35761 aaattctcta aataataaca gcctatggat accattgaaa atcttattat cgctattgtg
    35821 aaacctttga tttcacaacc agataatctt accattaaaa ttgaagatac tcctgacttt
    35881 ttagagtatc atcttgactt ggatgctcaa gacatcggtc gtgttatcgg caaaaaaggt
    35941 cgaactatta ctgcgataag atcgattgtc tactcggttc caacactagg aaaaaaagtt
    36001 cgcttagtta ttgatgagaa ataatcacta acttgagatg gattgaaaag cttgttgact
    36061 taaagtcaac aagctttttg aatagcaaaa atcttaatat ttctgaaatg aaaagattag
    36121 atttttctgt ctttaactaa aaagaagtta aagaatggct tagctgattg cctttataag
    36181 agattatact ggtttttgat agctgctgtc atgtaaaata gctacaattc atcttacgag
    36241 attgacctta gcattgccag tgcagtcttt attttccaac ctgctgtttg ttgtatgttt
    36301 atagttccct aaaaaatgct ctctcagttt tttgggggga attcct
//
LOCUS       DAUGOH010000017        32429 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUGOH010000017 DAUGOH010000000
VERSION     DAUGOH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32429
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.017"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(152..457)
                     /locus_tag="VH957_000904"
     CDS             complement(152..457)
                     /locus_tag="VH957_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEQ8558826.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            complement(469..888)
                     /gene="ruvX"
                     /locus_tag="VH957_000905"
     CDS             complement(469..888)
                     /gene="ruvX"
                     /locus_tag="VH957_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEQ8558827.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            complement(885..1154)
                     /locus_tag="VH957_000906"
     CDS             complement(885..1154)
                     /locus_tag="VH957_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEQ8558828.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            complement(1268..1666)
                     /gene="spx"
                     /locus_tag="VH957_000907"
     CDS             complement(1268..1666)
                     /gene="spx"
                     /locus_tag="VH957_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEQ8558829.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            complement(1957..3093)
                     /gene="recA"
                     /locus_tag="VH957_000908"
     CDS             complement(1957..3093)
                     /gene="recA"
                     /locus_tag="VH957_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEQ8558830.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            complement(3182..4453)
                     /locus_tag="VH957_000909"
     CDS             complement(3182..4453)
                     /locus_tag="VH957_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEQ8558831.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            complement(4522..5082)
                     /locus_tag="VH957_000910"
     CDS             complement(4522..5082)
                     /locus_tag="VH957_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEQ8558832.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADALENLSIIRHKLKLAATVNNAIA
                     VQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            complement(5092..5688)
                     /gene="ruvA"
                     /locus_tag="VH957_000911"
     CDS             complement(5092..5688)
                     /gene="ruvA"
                     /locus_tag="VH957_000911"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEQ8558833.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLDGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            complement(5690..6910)
                     /locus_tag="VH957_000912"
     CDS             complement(5690..6910)
                     /locus_tag="VH957_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8558834.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFDVAYYYFDETRPETHAFDHGKGLLASFQNYRQVFQDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            complement(6921..8903)
                     /gene="mutL"
                     /locus_tag="VH957_000913"
     CDS             complement(6921..8903)
                     /gene="mutL"
                     /locus_tag="VH957_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEQ8558835.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLVISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLE
                     NEEQSVFPGLDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGDVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            complement(9032..11587)
                     /gene="mutS"
                     /locus_tag="VH957_000914"
     CDS             complement(9032..11587)
                     /gene="mutS"
                     /locus_tag="VH957_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEQ8558836.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNL
                     KIDYNKKDGYYFHVTTSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVIAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPS
                     QVESSSAVRQGQLSLFGDEEKTHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            complement(11574..11926)
                     /locus_tag="VH957_000915"
                     /pseudo
     CDS             complement(11574..11926)
                     /locus_tag="VH957_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            complement(11923..12360)
                     /gene="argR"
                     /locus_tag="VH957_000916"
     CDS             complement(11923..12360)
                     /gene="argR"
                     /locus_tag="VH957_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8558837.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVSTPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            12651..14342
                     /locus_tag="VH957_000917"
     CDS             12651..14342
                     /locus_tag="VH957_000917"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEQ8558838.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLANIFAKMGYQPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAEIDHTVDEEARGWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            14430..14738
                     /locus_tag="VH957_000918"
     CDS             14430..14738
                     /locus_tag="VH957_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8558839.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKACHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(14765..15637)
                     /locus_tag="VH957_000919"
     CDS             complement(14765..15637)
                     /locus_tag="VH957_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8558840.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(15680..16558)
                     /locus_tag="VH957_000920"
     CDS             complement(15680..16558)
                     /locus_tag="VH957_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8558841.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVMGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            complement(16578..17519)
                     /locus_tag="VH957_000921"
     CDS             complement(16578..17519)
                     /locus_tag="VH957_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8558842.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIIPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            complement(17512..19260)
                     /gene="aspS"
                     /locus_tag="VH957_000922"
     CDS             complement(17512..19260)
                     /gene="aspS"
                     /locus_tag="VH957_000922"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEQ8558843.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTNGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANAQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            complement(19598..20878)
                     /locus_tag="VH957_000923"
     CDS             complement(19598..20878)
                     /locus_tag="VH957_000923"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEQ8558844.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDIYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFENISEQLLS"
     gene            21098..21280
                     /gene="rpmF"
                     /locus_tag="VH957_000924"
     CDS             21098..21280
                     /gene="rpmF"
                     /locus_tag="VH957_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEQ8558845.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            21296..21445
                     /gene="rpmG"
                     /locus_tag="VH957_000925"
     CDS             21296..21445
                     /gene="rpmG"
                     /locus_tag="VH957_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8558846.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            21739..22353
                     /locus_tag="VH957_000926"
     CDS             21739..22353
                     /locus_tag="VH957_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEQ8558847.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLRK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGEILEKYSRWFIAVVYLGLGIYILIENNSFDMLWAVLG"
     gene            22365..22703
                     /gene="cadX"
                     /locus_tag="VH957_000927"
     CDS             22365..22703
                     /gene="cadX"
                     /locus_tag="VH957_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEQ8558848.1"
                     /translation="MKKDSICQVNVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLTVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            22897..23670
                     /locus_tag="VH957_000928"
     CDS             22897..23670
                     /locus_tag="VH957_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558849.1"
                     /translation="MLYLNTQTDSDYKEIIFGDIAKFVENMFYHYFSSILFRDLETVD
                     KRMYSFSDDDLISIQSSCLRLSKTFANFNIQRKNFLASDETEMDTFHKKDDIDITVGE
                     KSYNLARSFRTSTINELTVFNFEEMFDIIWLMLGDNLIKSFEVNVCGILFELDGNGIP
                     STFRQENIDPLINKWWYDNVSTEIIPNLIKKLKENPLFNIGFLVDDILERMYKENIPK
                     SYLTSVPLVISKKARSTLSIKSNGSQKIDKSKFAQILSL"
     gene            23736..24488
                     /locus_tag="VH957_000929"
     CDS             23736..24488
                     /locus_tag="VH957_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8558850.1"
                     /translation="MAIPDLDKFSSSLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            24485..25088
                     /locus_tag="VH957_000930"
                     /pseudo
     CDS             24485..25088
                     /locus_tag="VH957_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25564..25845)
                     /locus_tag="VH957_000931"
     CDS             complement(25564..25845)
                     /locus_tag="VH957_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8558851.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGI
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRSALRIERFKKTYDVQTYR"
     gene            complement(25852..25896)
                     /locus_tag="VH957_000932"
                     /pseudo
     CDS             complement(25852..25896)
                     /locus_tag="VH957_000932"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            26299..27141
                     /locus_tag="VH957_000933"
     CDS             26299..27141
                     /locus_tag="VH957_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEQ8558852.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERVISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVIVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKVDWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMTVVLFALGIWLGLWMSQLE
                     EKYK"
     gene            complement(27188..27829)
                     /locus_tag="VH957_000934"
     CDS             complement(27188..27829)
                     /locus_tag="VH957_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEQ8558853.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIQPNEEVDKVFIVPLRQLLVTDPVYYRLEATPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWRMTAQFTKCLTDILNDESIAKKNPLDIEKSKGR"
     gene            28036..28362
                     /locus_tag="VH957_000935"
     CDS             28036..28362
                     /locus_tag="VH957_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEQ8558854.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
     gene            28349..28936
                     /locus_tag="VH957_000936"
     CDS             28349..28936
                     /locus_tag="VH957_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEQ8558855.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATAILRFSGRAFVAFIKWISNKKGAQA"
     gene            28933..30012
                     /locus_tag="VH957_000937"
     CDS             28933..30012
                     /locus_tag="VH957_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEQ8558856.1"
                     /translation="MKNISRKCFITSVLCIILGGILLGAGYATGGLQDIKHQTAPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKFIDPIVTTVTGKTLSLSQKP
                     KDVVITGGIEILGFTLNNSRQEKNYRSITITVPEKTSLNEVKGSNVPHTTLSNLTVQD
                     MQFDGNLTLLHTKVKKATITGMLEATKSQLTNLELKADYSFSNLTDSSVENGTISLGN
                     GQLTTKDTTLKAVNIQSLHPGGIEAERTTLENVTFTVSKSKEEEENDYYDNDAIFTAH
                     ALTLKGTNTITGGDIDVDITLTKAKAIAYRARTENGKVSLGSQLTPAKIGKESTSDVI
                     SYVAENKAATGNLTVNLNKGDITIK"
     gene            complement(30128..32401)
                     /locus_tag="VH957_000938"
     CDS             complement(30128..32401)
                     /locus_tag="VH957_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEQ8558857.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKKGDYYMV
                     ITLPEDLSQRATTLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMTKLKESVSQNITKI
                     YTSAVFRSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEELSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGTNALSSKSGELLDGSHQLSEGATKLADS
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
BASE COUNT        10068 a         6812 c         5574 g         9975 t
ORIGIN      
        1 tctctaaatc tatgcaaagg tttagcctta taattattaa taaatttatc atttaattct
       61 tttatcatta tcacctcctg cttatttatt cgaaaataac attaaaaaaa tagccctcac
      121 ggctactttt taacatagtg tcactaacaa tttagttctc atctagaaaa ctattaaata
      181 cctcttcaat catatcccat tcagcatctg aatcctcagg aatcggttgt aaatcccctt
      241 cagtaccatc ttcattttca gtaaatgaat aggcttggat ttcaatttca ccagactcat
      301 cttcttcaga tcccgctgga accaagagaa cataattttt accaaactct tcacgaccat
      361 caattgttaa taaaatttca aacaaggttt catttccttg ttcatccaca agtgtgataa
      421 cttcgtgttg gtggtcgttt tcatgattat gtgtcatttt ttatctcctt aaaaattccg
      481 atttaaatag ttctgtaaaa tgagttgtgc agctaattta tcaatgactt tttttcgctt
      541 accacgacta atgtcagctt gctcaataag catacgctct gcctcaacag tcgtcaatcg
      601 ttcatcttga taatggactg gaagtccaaa aaggtgctct atgtggtttc cataagttat
      661 acttgcatca acacgtggac cattggtgtt attcatattt tttggcaatc caataacaaa
      721 ctgttcaact tggtactgct taacaagctc ttctaaacgt gtaaagccaa attctgcttt
      781 ttcctcatca atcttgataa tttcaagtcc ttgggctgta aagccaagag gatcactaat
      841 agctacacca accgttttcg agccaacatc aagtcccatt attctcattt aacatcaatt
      901 ccatttcctt gtaaatagta gcgaacaagt tcttctacaa tttcatcacg ttcatattta
      961 cgaatctgat ttcgagcatc attataacga ggaacataag ctgggtcccc actcaagaca
     1021 taaccaacaa tttgattaat tggattataa cccttttcat caagtgaatg atagactgct
     1081 gttaatgttt cactaatttg tcgtttgtcg ccatcatcca acttaaagcg gactgtttca
     1141 tctgtaaatc ccatacttac accttctttc taaaattaag tgctatgctt tattatagct
     1201 tatttctatt aaataaacaa gaatttcaag cgaagaaggt atttaaaaaa aagctctaca
     1261 agagctttta gagtgcagca cgtaatcgtg cttcagtatt ttcaatatta cgaatagagc
     1321 gaggtaaaaa agcacgaata tcgtcttctt tgtagcctac ttgcagacgt ttatcatcaa
     1381 tcaaaatggg acttttaagg atgcgcgggt tatcttgaat caaatcaata acctcactaa
     1441 cacttaattc ttcaatatcg caatcgagag ctttggcata acgattttta gatgaaacaa
     1501 tgctctccac tccattttcg gtttttgata aaattgctaa aatttcttct ttagttagcg
     1561 gttcttttcc taagttctgt tctttataag caagcttatg ggcatttagc caagttttgg
     1621 ctttcttgca gctcgtacaa cttgaaatcg tgtaaatttt aatcatgttg ctgactcact
     1681 ttctatttcg tgatagcttt attgtagcac agtttcttat ctataaatat aggtctttgg
     1741 acctattttt ttaattttaa agatattatc ttagtaaaat aaggtttttc acctgtattc
     1801 ccttgaatta ttagttattt taattttata tcagttaacc taagttctgc tctctcacat
     1861 ctttttaaat gatggtttct attcacccac acacctatga acagtagttc tactaacctt
     1921 taaaaataca ttttaaaaag ccctgaaggg ctctttttaa tcttcaattt caataccatt
     1981 atctaaatct aaagcaagat catcggtttc ttctgatgct actgccatag cagattcttc
     2041 ttcgctttct tcaagcaaac caaatttaac acgtacttta cggtcgattt catcaaacaa
     2101 ttgtggatga tcggccaaat aacgcttagc attttcagaa ccttggccaa tcttctcacc
     2161 attataagag aaccaagcac ctgctttttg gataatgtcc aaatcagaag caattttcac
     2221 aagctcccct gtacgagaaa taccttcccc atacatgatt tcaacttctg ctaccttaaa
     2281 tggcggagcg accttgtttt taacaacctt gattttggtc tccttaccaa tgctgctatc
     2341 tttttggtca ccagttcctt taatttgagt tgttccacgc acatccagcc gaacagaagc
     2401 atagaatttc aaagctcgac cacctggtgt tgtttcagga tttccaaaca tcacaccaac
     2461 tttttcacgc aattggttaa taaagatagc gatagttttt gttttattaa tagaagctga
     2521 taatttacgc atggcctgac tcatcatacg tgcttgcaat ccgacatggc tatcgccaat
     2581 atcaccatca atttcagcac gtggcactaa agctgctact gaatcgacaa caaccagatc
     2641 aaccgcacca gaatcaatca atttacctgc aatttcaagt ccttgttctc cagaatctgg
     2701 ttgagacaag aggagttcat caatattaac cccaagcgca gcagcataag ctggatcaag
     2761 cgcatgctcg gcatcgataa aggctgcgat tccaccttct ttttgagctt gtgctacagc
     2821 atgtaaagcc acagtcgttt taccggaaga ctctggacca tagatttcga tgatacgtcc
     2881 tttaggataa ccaccagctc caagcgcaat atcaagagct agacttcctg aactcataac
     2941 ctgaactttt tgctctgcac gttcccctaa tcgcatcact gcgcccttac caaaatcttt
     3001 ttcaatattt ttcaaagcat catcaagggc tttgcgacgt tcgtcaccaa acttcttagt
     3061 gatttcttca ttctttttta atttttttgc caatactttc tcctcttttt taacaaacca
     3121 tcgtcagcag gattaatcta cataatcgta aaccatatcc tactatagct actaaataac
     3181 attatagcaa attctcaagt tttaataaag ttttacggac catattaaag gcatgtaaag
     3241 tagcgatata gcgcacatcc aaacgacttc gcccgctaat caaaaccttt attgattcta
     3301 ccttattttg agtggcaaga ccaatgaaaa ctgtacctgc aggctgttcc tccaacatat
     3361 ctggtccggc aacacctgtt aaacttaccc caatatcagc accagtcaat aaccttgctt
     3421 gctccgccat cccctcggcc gtataagcac taacaacgcc atgcgatttc aactcctcta
     3481 aaggaaggcc tagcattttc gctttttctt ccatgctata agtcacaaag cctccattga
     3541 atacttgaga agctcctgga aaactcgcca aagttgactg aaataatccc gcggttagac
     3601 tttctgctgc tgtaattgtc ttatcatatt ttactaagag ctcaaatgtc tcacgcgcta
     3661 aggaattatc ctccccatag ccataaaaga catcagctaa gggttgacct tcaagagttt
     3721 ttcgggatag tagctgcgct tctagctgac ctaacttttt atctgccaga gcttggtttt
     3781 cagtttttgt tgataagcga agagtcactt cgccagtctt agcatacgga gcaatggttg
     3841 gatcagtttg attctcaata aaatctgaca agactgttac caactgactt tccccaatac
     3901 caaaaaagcg tagtaccttt gaatacaatg tactgtattg ttttgacaga agtggtacca
     3961 attcttcatt taccatcggc ttcaattcac ttggaggacc cggtaagaca acataactaa
     4021 taccatcgac tgtgatgaac ccaccaaccg caagaccagt tttatttggc aaagggattg
     4081 acccttcaat cacttgtgcc tgtcgctcat tatttggtgt ccgtgatgaa ggcttgcgct
     4141 tagcaaaaaa gtcatctagt ttctgacaag cttgctcatc ataaaccaag tctttcctaa
     4201 ggtactttgc taaagtttgt ttggttaaat catctttcgt tggaccaagg ccaccacata
     4261 aaattaccaa gttactacgc tgactagcag ttgtaatcac tgaaagtaaa cgctcctcgt
     4321 tgtccccaac agccgtttga aaatagacat caatacctag ctctgccatt ttttccgaca
     4381 gaaattgagc attggtattc acaatttgac cagtcaaaat ttcggtacct actgcaatca
     4441 gttcagcttt catttctcca cctacttatc tattcgtaat ctgatctcat tttatcaaaa
     4501 aatcttccaa ttcacgaaga attagaagat tctattgaaa acacaagcct cttcatggtc
     4561 atttaccaaa cccgatgctt gcataaaaga ataaaccgtt gtaggtccta aaaatttaaa
     4621 tcctcttttc tttaaatcct tagctaagcg aatagataat tctgtttgag caggaacaag
     4681 attctcttga ttgacaaggt tgttaattgg ctttccccca acaaaattcc agagataagt
     4741 tgaaaaacta ccaaactctt cttgaatttt ctgtactgcg atagcattgt tgacagttgc
     4801 tgctagcttt agcttgtggc ggataatgga tagattctct aaagcgtcag ccatttcctc
     4861 cgaggtaaag gctgcaaccg atgcaatgtc gtaatgatga aaaacagttc tgaaagcttg
     4921 gcgttttttc aaaacagtca gccaggataa gcctgactgg taactttcaa ggcagagtaa
     4981 ttcaaaaaaa tctctatcat catgtagggg ttgaccccat tctaaatcgt ggtaatcaca
     5041 gtaaagctgg ttatccttag gaacccatga gcaacgtttc atgtgaaaca cctagccttt
     5101 cattaatagt ttaagggctg atttgatgta ttgttcggct gtctcagagg ttccttcaaa
     5161 gaaggcacga attttcttca attccgttgc cttataaccg agggcaagga gggcttcaat
     5221 cgcttcgtcc agttgagtat tgcctgcttt attgctgcgc gctttggtat taccagtctc
     5281 ttgtggagcc tccacaaatt tgccatctaa gtcaagaacc atttgctgcg ctgttttttt
     5341 accaatttta ggaaatttca ttaggtactt aatgtcactg ttatcaatgg cattcacaag
     5401 tccctcatta tcatcaactg ccacaatagc aagagctgtt gtcggaccaa tacctgatac
     5461 agaaattaat ttcagaaaaa catctttttc atcttccgtg tgaaaaccaa acaacaggtg
     5521 agcatcctca cgaatcactt gatgcagata aatggttacc aattggttga cactatctgt
     5581 aaagctataa ggattggcaa cattaatcat gtagcccaat ccattagctt caacgacaat
     5641 gtattttgcc gtaattttgg tcaattgacc tttaatataa tcgtacatat tacacctttt
     5701 tcatttttgc agaaacaacc gtaaaataaa tccctagcaa agcaatgact acaaataagc
     5761 attgcacgcc taaaggacct gtaaaatggc tgacagatac taggagacta gccaaaatag
     5821 cacctagggg ttgtgccatt gacacaaaac ctgtataaga tcctatttgg gaatgatcca
     5881 tcatatcagc acgtaggact tgactagcag gaacatttat catttcccca aaagttaaca
     5941 aaacaactga taaccagata gcatagaact gcgtaaaggt aaatgccaag agcatcccta
     6001 gagtaaatag taaagaacca accacaagct gaggtaatag tttccatttt tccgttaatt
     6061 tatttactac tgtcatgaaa aggacaatca gcaatgtatt agttaaaacc attaatgata
     6121 acattttaga actagttact tggaaaccta acacagccgt tggctgaaaa tacagtttca
     6181 aatggactgg cacatagtta tccatctgca tccagatact accagaaaag atggcaccta
     6241 aggtaaacaa gacaaaggca cgatcctgaa acacctgacg gtagttctga aaactcgcca
     6301 gtaatccttt accatgatca aaagcgtgtg tttctggtct agtctcatca aaatagtagt
     6361 aagcaacgtc aaaacaaagt acattaacga gtaataaggc tactaacaag gctaaaaaat
     6421 gatggtcata aaaaagccca gatagccctg caccaaacat gacggcaata ttgataaacc
     6481 aataattgat ggtgtaaaca aatcgacgat tactctcatc agtcaaatca attaacatag
     6541 cttcataggc aggaccataa aaactagaag caatctctac caataaaata cccgcaaagg
     6601 ttaaccaagg aatagctgca ttaggcaaat tagctaaaat agtcagaaac cagcctagtg
     6661 ttgttcctac tgacccaatc ataatgactt ttttacgacc aagagcatct gacagatgcc
     6721 caccgtataa agttccaaca aatcccatca aactggtaat catcattaag aggcctgtcc
     6781 aaaacgtacc aaagtaagtc gtataataca tggccataaa gggaaagata ctactgccta
     6841 aggtaatggt cacaaagcgt accagttgcc tcagctgaat ctgcttagga aggtttaaaa
     6901 actcttgcat ctcatcctct ctaatatttt cctagctctc gcaggctagt gtgattttct
     6961 tgaattcgac ggaacatttt ttccatatct gccttactaa aattaatcaa tacgggtcta
     7021 ccatgagggc agttataagg attttgacat tgggccaatt gcagtagcag atttcttgct
     7081 gaataatcat ccaagctatg atttgccttg atagatcgtt tacaactcat cataatagct
     7141 aactctgctc ggtaagtttt gatagatacc tcattggtta gaagcaacat gtcacacatt
     7201 tcatagacac cagatgcaat ctcttcttct ttcatccaga taggatgctc cctcaaaatg
     7261 aaagtattgt gcccataaac ttctaagaag ataccgactt catttaagag tgccattttc
     7321 tcctgtaagt taatgaaatc agaaccagaa aactcaaaca aatagggcac caacaattgc
     7381 tgtaaactac tgtcaacgtc gccaatctta tcacgataat attcgtattt aacccgctcc
     7441 tgggcagcgt gttggtcaat tataaataaa ccatcttttc cctgagcaaa gagataagtt
     7501 ccgtgcatct gaccaaaata atccaatccg ggaaacactg attgctcttc attttccaag
     7561 cgattcaaca tttgagataa cttttgtctg ttttttaagt caagattagg atgatcagtc
     7621 tcggtaaagg tattctgggg acgacttgcg tgtttaaccg aagaaggtcc tataacttct
     7681 tctgagtggg gtaacagctc tgctttttca acctttacac tgttgtcaac agcgccggaa
     7741 taaaaatcag tttcaggtat tttttccgag acagccgact ctttgacaaa aaagtcattc
     7801 ttttgaggat cataataaag ccccctagac tgtaaaggaa gttgtgtttg ctctggttta
     7861 gagaaatgtc gtgtgcttga tttggctaag ttttccagag catctggaat caaatcttgt
     7921 tccttaagac tctctgaaat agccgtgcta attaaagcca ttaattcacg ctcttttgaa
     7981 atacgaacct cttgttttgt gggatgaaca ttgacatcgg ccaaataggg atcaatctga
     8041 atatcaatca caacaattgg gaaacgtcca accatgagct tagaaccgta accatcaaga
     8101 attgctcgat taagcaagaa attcttgatg taacgcccat taaccaaaat cgtcatgtaa
     8161 ttacggttgg cgcgtgtcaa ctctggcaag ctaacatagc cggaaacttc aaaatccaaa
     8221 tcagcattag agataaccag catttttttg gtagtattta aaccataaat ccctgcaatt
     8281 gcttggcgta aatcgccagt tcctgatgtc tgagttaatt ggcgaccatc actaatcagt
     8341 gtgaaagcaa cttctggatg tgccaaactc aaccggttga ccacatctac aatgtgagct
     8401 aattctgcct gtaaactttt catatatttg agacgagcag gcgtgttgta aaaaaggttt
     8461 tcaaccttaa ttttggttcc agtaggagtt gagatcgctt caagtgtctc aatttcccca
     8521 ccagtagcta taagaagaga accgtgagtg acttcttttg ttgctgtttt tatcgtgatt
     8581 ttactgatag aggcaacaga cggtaaagcc tctccacgga agccaagtgt tctaattcta
     8641 aacaaatcac tctgactctt aattttacta gtagcgtggc gacgcagact taaaggtaaa
     8701 tcttcatgag acattccctc accgttgtct gtaacctgta tcatcttaag gccagactct
     8761 tcaatttcaa cggtaatctg gctactttta gcatcaatag cattctcaac caattccttg
     8821 acaacactcg ctggcctttc tacaacttca ccagctgcaa tttggttggc gagaacttcc
     8881 ggtaattcaa taatgtttgt cataatttcc tcgcattctt atggactatt ataacacact
     8941 taataaatag ccgaaggcct cggaccgttt ttgacagaac aaaaagatgc tttctatatt
     9001 gaaggcatct ttttcatttt cagctgaaag actataacaa ctttttcaat tcgtaaaggg
     9061 ttgtcattgc ttgaagcggg gtcatgttca tgacatcaat agcttccagt gcttgcctaa
     9121 tctcatgagt tttctcttca tcaccaaaaa gggataattg cccctgtcta acagcgctgc
     9181 ttgactcaac ttgtgaaggg actgatatta tctcagtaga tcgtgactgt gtttctaaac
     9241 gggtcagaac ttcgtctgct ctctttaata gggattttgg cagtcctgct atttttgcca
     9301 catgaatacc gtaagattta tccgccggtc cctcagcaat cttatgaagg aaggtaacat
     9361 cgccatcttt ttcaagcgtt gctacatgaa cattgactag acttgtcaac ttagttgaca
     9421 agtctgtcaa ttcatgataa tgcgttgcaa atatggtctt agcaccaact ctatcatgga
     9481 tatattcaat aattgcctgg gctaaagcca taccatcata agttgccgta cctcgtccca
     9541 gttcatcaaa tagaataaga gagttgtcac ttgcgcgttt gattgcttgg tttgcttcca
     9601 tcatctccac cataaaggtt gattgcccag aaatcaaatc atcagcagcc ccaatacgcg
     9661 taaaaatcgc atcaaataaa ggtaaatcaa catggtcagc agccacaaat gaacccatct
     9721 gggccatgat aaccgttaag gccagctgtc tcatataagt cgacttacca ctcatatttg
     9781 gacctgtaat cagctgaata ctggtctgtt ggtcaaaaga gatactattg ggaatgtatt
     9841 cctgcactcc cataaccttt tcaacaaccg cgtgacgacc ttcttgaatt gtaatcacat
     9901 gattatcatt gaactgcggc cggatataat gattggtttc agcaatgact gctaaacttt
     9961 gcaaaacatc caccgttgcc aaagttttag ccagtttctg taaacgatta atataggttt
    10021 caacttgagc tcgaatacac ataaaaatat cgtattctaa actagatgac tcttccctag
    10081 cctctaacat ctgaccttca atcttagcca attctgctgt tccataacgt tcagagtttt
    10141 ttaaagttgc ctttctgaaa aaatgctcag gcactaagct aagatttgaa gtcgtaacgt
    10201 ggaaataata tccatctttt ttattgtaat caatttttag attattaatg ccacttgctt
    10261 gacgctcttt agcctcaata tccgcaatcc agcctgttcc ttctcgcatc actttacgat
    10321 aatggtccaa gcgctcatca aaaccagtac gaataatact gccttcacta atagttgctg
    10381 gtgcgtctgg atcaatggct gttctaatca agtattccaa ctcaggcaaa ctgtcaatat
    10441 cattgacaag tttgtcaaca caaggactgt taaaagactc taagatagct ttgatataag
    10501 gcacttgggc taaggtatgc cccaattgaa gtaaatcttt cggatttgcc ttgccaaaag
    10561 acacgcgact agataagcgt tcgatgtcgt aaacaccttt taaactattg cttaaatcgg
    10621 ttcgctcaat aaaagcattc agaaaaactt gaataatttc ttgacgctct aaaatagctt
    10681 ctttagaaac caaaggtcga tcaatccatg agcgcaaaag cctcatcccc atagctgtct
    10741 tggtttcatc taaaagccaa tacagacttc catgtttttt attagtccta gcattttcta
    10801 ccaaatctaa acttgactta gtggcatacg acatctgcaa ataatccttg atctcatagt
    10861 gaaccaaggc ttgcaagtgg ctgagttctc gcatttgtgt cttgtgaacg tattgcaaga
    10921 gttttcctgc cgctgtgagt tctaccgttg tcaattggcc gtcaattaaa gatttatctt
    10981 catagaccgt ttcttcataa gaaagcagca aattcatctg cttgaccaaa atcgtctgtt
    11041 cttcttcaga taaatcaaaa cctagtaaga cttcttttgc cttgaggttt tggatttcgc
    11101 tacgaacact cgtaaagtcc gccaaatctg tcacgcaaaa ttcacctgtg gatacatcca
    11161 tataagccaa tccataacgg caaccatcaa agtcaacagc taccaaaaag ttattggcgc
    11221 tatctggctt agctgaatcc acaaccgttc caggagttat gacttgaacg acctcacgct
    11281 tcaccacccc aacagcttgc tttgggtctt ccatttgttc tgcgacagca accttgtaac
    11341 ccaactcaat taacacatca atgtattgtt gggcagaatg atgtggcacg cctgccatgg
    11401 gaattggatt ttccgcattc ttgttgcgac tggtcaaacc aatttctaag agttgtgctg
    11461 ctttgacagc gtcctcgtaa aataattcat aaaagtcacc catcctaaaa agcaaaaaag
    11521 catctggata atcttttttg atgtccagat actgttgcat tccaggagaa atgttagttt
    11581 ttgccatttg ttaactcctt gtttaactga tcttctatac gtttggtgat atactgagtc
    11641 acatcacttg catcttgcat cttttctcga taatcatcaa ttaatggctg atgactgagc
    11701 ctatcttcta gttcttttgc cctgcttgca gatactgtcg cagccttttc tttatctact
    11761 ttttttgaaa agcagggcat cttgttgata gcgtttcatc tgataagctt actttttaaa
    11821 atcacggagc ttagacagct attgcttcac ttctttataa gcaacgatac tagaattcat
    11881 ggatagcaag aatcaattgt gtcaaagact cttaatagct agtcataggc ctgcagccaa
    11941 atctttttca aagcgtttag caatctcttc gtctctgcaa atcacaagca aggtatccgc
    12001 accagcaatg gttcctagaa tatcttcaat ggcatcattg tcaatcaaat tagctagaac
    12061 atcagcctct cctaaattgg tatggagaac cagcataaaa cctgctcgat caactttcaa
    12121 aacataaaaa cgcacctcag gactaaatgg tgttgaaacg ggttcagaca aactataata
    12181 gagtttgcct tgttcatctc tcaatttcaa aaggccaatt tctcttaagt cccgagatag
    12241 agttgcttgg gtgaccacaa tgccttcttt ttgaaggtga tttttaatat cttcttgtgt
    12301 gccaatatgc tctgcttgaa tgattcgctt aatctgctgt tgacgctcca ttttattcat
    12361 gatatatcac cccaattgta taattatcct ctcaaattat aacaaaaaaa gtgtattatt
    12421 tcatcttcgc ccagctattt tcagcaattt tttatcaaat tcaactagaa tttcacttga
    12481 aaactgttga aaagaaacct catttctctt tttataacat tttcagaaaa acaacaacct
    12541 caagcaattc atttccttga aagtttcagt ataatttatc aatcctctcc tcgtttattt
    12601 taaagaaata tgttagaata gggtgacaaa caatttttag gagacgctgt atggatacta
    12661 aaactctaat cgcaagtgaa atagctaaag ttgttccaga attagaacaa gatgctattt
    12721 ttaacttgct tgaaacccca aaaaattctg acatgggaga ccttgccttt ccagccttta
    12781 gtttagcaaa agtccttcgc aaagcccctc aaatgattgc tagcgagtta gctgaacaga
    12841 ttgatgagag ccaatttgaa aaagtcgtag ctgtcggccc ttacatcaac tttttccttg
    12901 ataaagctaa gatttcctca caggtccttg aacaagtgat tacagcaggt tcagactatg
    12961 ctcagcaaga cgaaggtcaa gggcgaaatg ttgctattga catgtcaagc ccaaacatcg
    13021 ctaagccatt ttcaatcggt cacctccgct caacagttat tggtgatagc cttgctaata
    13081 tctttgctaa aatgggttat caacctgtaa aaatcaatca ccttggtgac tggggtaaac
    13141 aatttggtat gctcattgtt gcctacaaaa aatggggaga cgaagctgct gttcaggcac
    13201 atcctattga tgaactctta aaactttacg ttcgtatcaa tgctgaagct gaaattgatc
    13261 acaccgttga tgaagaagct cgtggatggt tccgtaaatt ggaagatggc gacaaagaag
    13321 ctactgaatt atggcaatgg ttccgtgatg aaagtttact tgagttcaac cgactttatg
    13381 accaattaca tgtcaccttc gatagttaca acggtgaggc cttctataat gacaaaatgg
    13441 atgaggttct tgacttatta gaagctaaaa accttcttgt agaatccaaa ggtgcccaag
    13501 ttgttaacct tgaaaaatac ggcattgaac accctgcctt gatcaaaaaa tcagatggcg
    13561 ctactcttta cattacccgt gacctagctg ccgcacttta ccgtaaacgc acttacgact
    13621 ttgctaaatc cgtttatgtt gttggtaatg agcaagctgc tcacttcaaa cagttaaaag
    13681 cagtgctaaa agaaatgggt tacgattggt cagatgacat gacacacgtt gcttttggac
    13741 ttgtcacaaa aggcggtgct aaattatcaa cacgtaaagg taatgttatt cttcttgaac
    13801 ctacagttgc tgaagccatt aaccgcgctg cttctcaaat tgaagcgaaa aatccaaatc
    13861 ttgctgataa agaagctgtt gcacacgctg ttggtgtcgg tgccatcaag ttttacgatc
    13921 tcaaaacaga tcgtatgaat gggtatgact ttgaccttga agccatggtt tcctttgaag
    13981 gagaaactgg accttatgtt caatacgctc acgctcgtat ccaatctatt ctacgtaaag
    14041 ctgactttac gccatctgca accaccactt acagtttagc tgatgctgaa agctgggaaa
    14101 ttatcaaact tatccaagat ttcccacgca ttatcaagcg aacatcagat aactttgagc
    14161 cttctattat ggctaaattt gctattaact tagcacaaag ctttaacaaa tattatgctc
    14221 acactcgcat tcttgacgac aactcagaac gtgataaccg cttagctctc tgctatgcaa
    14281 ctgctactgt tcttaaagaa gcgcttcgct tactcggtgt tgacgcacca aatgaaatgt
    14341 aagtaataac atcactaagg ctgtcacatt tatgacagtc ttagtttttt atattataat
    14401 aatagcacaa tatgttacag gagaatgcca tgccatcaga aaaagaaata ttagatgctc
    14461 ttagtaaagt ttatagcgaa caagtaatac aagcagatga ttattttcgt caagcgatct
    14521 tcgagctcgc cagtcaactt gaaaaagagg ggatgagctc actactagct acaaaaattg
    14581 actcacttat caatcaatac atcttaacac atcaatttga tgctcctaaa agcatatttg
    14641 atcttagtcg cttggtaaaa acaaaagctt gccattacaa gggaactgct atatcagcta
    14701 ttatgcttgg tagtttctta agtgggggac caaaataaaa atacaggctg tttgacctgt
    14761 atttttattt atcataattt cttcggcgaa ttttaaaatc agagctaata acttcgtcca
    14821 catcaataat ggagataaag gcatctggat ccaaaccagc taaaatacgt ttgacttccc
    14881 gaacttcagt tgggttcaag gtcacataca tgatattgta atcattacca gagtaagctc
    14941 cttgaccttt caagtaagtc actccacgat tgatttcggt taggatagct tgagcggcag
    15001 cctctgaatg cttggtaata ataatcattc cacggatagt gtaaccacca ttttgaacca
    15061 cactaatcat ttggctaaaa acaaagcttg ccaccaaagt ataaagcatg tgttttaaat
    15121 ccacataagt caacgaagct gtcaatacaa gagcatccac caaaagcaaa gtttgaccta
    15181 gcttagctcc aaatttttct tctgcaatgc gaccaataat atccgttcca cctgtggttg
    15241 caccatagcg aaaaacaatg ccactcccaa tccctgaaaa gagacctgcc actacagcca
    15301 ccaacatcat gtcattttcc aagccaagtt cgataggaac tttttgccac atccagataa
    15361 aagcggacat cagaactgtt ccatagatgg ttagagccaa agaacgcttc ccaaaaatct
    15421 ttgcccctaa aataaaaagt ggaagattaa ataagagaga agagtaagca ggattaatcc
    15481 caaaatgcgc gtgtaaaatc aaggttattc ctgccacacc accttcagcc aaagcattag
    15541 ccatgttaaa attaacaaaa ccgaaggtat aaatggctac acctagggca atcaaaaaca
    15601 gttttagtag tttagtcaat ttatcgtgat gtgccatcct ttatcctcac tattcttcgc
    15661 aggcaactct aatgctcatt tatttcctct ttttatggta tttgctttta atagttaaaa
    15721 attctgggct attgacttca ttaacatcaa aataagtgat aaaggcattg ggatcaacct
    15781 gagttaaaaa agcttttaat tccctaatat ctcttcgccc caaagccaca taaatcactt
    15841 ttttacggcg cccagaatag gctccttcac ctgttagata agtaactcct cttcccaatt
    15901 cgtccatgat gaaccgggca attttctccg cttgttctga aacgataaaa atgccacggg
    15961 ctgaataacc accttgttgt accaagcgaa caatttgacc atacataaag ctagcaatca
    16021 gagcatacat catttgcggc agggaaatat aagtcaaaga gacaatcatg acaaaaagat
    16081 caatgcctaa aagagcttga ttcagctgta gtcctaactt gtcttctaat aacttagcaa
    16141 taatatctgc tccaccgatg gttccaccat tgcgaaacac aagaccgcca cctagaccac
    16201 caataattcc agccatcaag gaaacgacta aattgtcatg gtccaagtca acgaccaaag
    16261 gaaagcgttg aaacagccac acaaaaaagt aaagtgacaa aatacccatt actgtgtaaa
    16321 ccatggctct tttcccaaaa catctagctc ccaacaagac caaaggcaaa ttaatcaaat
    16381 agcctatcaa agaaggatca atctcaaaaa gtgccttacc aactagggtg agaccagcta
    16441 aaccattggc tgcaatgcga ttagccatgt aaaaataaac aaaagcaaag gcgtagatag
    16501 cagctcctaa aataataaag caaaatttct ttaactgtaa acgttggtca attgacatga
    16561 cacctcctgt gtttttctta atcatcttcc acaaaacgac cgataattct aacattctca
    16621 gccactgaaa caaaggcttg tgggtctgtt tttaacatca gccatttgaa ttctgggtat
    16681 tcttcacatg tcaaaatggt aatcaaaact gctttttgtt catgcttgta agtcccttct
    16741 gcgtcgttga tactggtcac cccgcgatgc agacgtttat ggatcatatg aatcacacgc
    16801 tctggatggc tggtaacaat agttgcctgc attttctttt gcttggtgaa aatggcatcc
    16861 gtaacacgac ttgatacaaa gatagagacc atagaataaa gggcgtactg ccagccaaat
    16921 aaaatccctg caaaggctaa aattgcacca ttaaccatca atgagagact gcccacatcc
    16981 ttgcctgttc gttttctaag ggtcaaactg acaatatcag tccccccact agagatacgt
    17041 gatttgagac ctgtaccaat tcccattccc ataaccaaac caccaaaaat agcattgata
    17101 agaggatcag tcgtcagcgt cacttgaggt atgatttgaa taaagaaaga actcatgctg
    17161 actgtgataa aggtaaaaat ggtaaattga tgcccaattt tataccaagc taaaataagc
    17221 aaaggaatat taatcaaata aaacgcaaag gcgatgggaa aatcatagcc taaaagacga
    17281 tgactaagag ctgaaaaaac ctgtgctaga ccagttgctc cacttgaata aacatgccca
    17341 ggctggaaga aaaaattcac agcaatacta gagagaatgc cataaagcag agaagccgaa
    17401 atcttctctg catatttttc tcttgaaata cttcttagag cgtggagtag gccaactttc
    17461 ttggcccctc tactaatgac atatttaact tttttcttat aggttgtttt cttaatcatg
    17521 actttctatt tgaagactga gttcttctaa ttggttttca gaaacaagac taggtgcttg
    17581 cgtcattgga tcagaggctt tgttattttt agggaaggca ataacttctc gaatattgtc
    17641 ttttccagca agcaacatga caaaacggtc aagaccaatt gccaagccac catgaggagg
    17701 aaagccgtag tccatcgctt ctagtaagaa accaaattgg gcgttagctt catcagcggt
    17761 aaagccaaga gccttgaaca tgcgctcttg catctctttt tgattgatac gcaggctacc
    17821 accaccaagc tcgtaaccat ttaaaacgat gtcgtaagca atagcccgta ccttagccaa
    17881 atcaccctct aactcatgag cagattctgg cgttggaaga gtgaatgggt gatgagctga
    17941 catataacgt ccttcttctt ctgaccactc aaacattggc caatcaacca cccaaaggaa
    18001 attaaactgc gactgatcaa tcatgtcaag gtccttggca atacgattac gaagggcacc
    18061 taatgtatta ttagcaacct caagagtatc cgctacaaat aaaaccaaat cattctcagc
    18121 aagttttaat tggcttgaca actctgtctc aatagctgtc aagaacttgg ctactgggcc
    18181 tgccaattga ccatttgtca ccttaaccca ggcaaggcct ttagcaccaa attgtttggc
    18241 aaactcagtt aatttgtcaa tatctttacg agagtatcga tctgcatttc ccttaaccac
    18301 aatcgctttg acagctggtg cttctgagaa aaccttgaag tcaattccct tgacagttac
    18361 tgtcaagtct tgtaaaagca tctcaaaacg tgtgtctggt ttatcagagc catagctatt
    18421 cattgctaca tcgtagctca tacgtgggaa tggtagggtt acatctattt cttttgtctc
    18481 tttcatcact ttagcaatca tgccttcaac gatgtcttga atttcttgtt cagaaaggaa
    18541 tgacgtttcc aagtcaactt gtgtaaactc aggttgacgg tcaccacgta gatcttcatc
    18601 gcggaaacat ttcacaattt gataatagcg atcaaagcca gcattcatca ataactgttt
    18661 ggtaatttgc ggactttgtg gcaaagcata gaaatgccct tggctaacac gacttggtac
    18721 cagatagtca cgcgcacctt ctggagttga ttttgtcaac ataggtgtct cgacatcaat
    18781 aaactcaagg tcatcaaggt aattacggat agaatgagtc acttttgcac gtagcttgaa
    18841 gttttctaac atttctggac gtcgtaaatc taagtaacgg taacgtaaac gcgtgtcatc
    18901 acttacttca acgtcatctt taatttcaaa aggcgtcgtt ttagctgtgt ttaaaatggt
    18961 caaagcagat acttttaact caaccattcc tgtcgccaac ttatcattgg cttgttgtcg
    19021 agcttcaaca aaaccttcca cttcaatcac atattcacta cgtaggcgtt cagcagttgc
    19081 catcacatca ctggaaactt cctcagggtt aatgactaat tgcatcacac cctcacggtc
    19141 acgtaaatca ataaagatga gaccacccaa gtcacgacga cgactgaccc atcctttcaa
    19201 tgtgattgtc gttccaatgt gttcttcgcg aacacgccct gcatacatgc tacgtttcat
    19261 aaataaattc cctaaaacaa acagaatcct gtgaaacctg ctcgtttcca attcctttca
    19321 ctatataaat caattaattc attccctact attatagcaa aaagccctta aaaaccccac
    19381 ccatttaaaa agagtttttc taaagataaa gcaagaatac tgagtcgtca gcattttgac
    19441 atatcaggtg tcctcacaga atactaagaa agctaatcaa tccccttaca gaaaacaaac
    19501 aggtgcaact cccttctaaa aagagaagtt acacctgttt tagtgattat cttctaaaca
    19561 atcatatcaa cacaagctta tgacgacaat aaaatcatta agacaataat tgctctgaga
    19621 tgttttcaaa gttggtcatc atatcttcaa aactgacttc cacttcttga cggctacgat
    19681 tattcttaat cacagctttg cctgcttcaa cttcactttc tcctaaagtc attaccaatt
    19741 ttgctttaaa ggtatcagct gatttaaact gagccttaat cttacggcca aggtaatctc
    19801 gttcagctgt aaacccttga cggcgaatgg cttgaaccaa ttctaaagct ttgctattag
    19861 caccatcacc taacacagca aggtaaatat ccatctctgt ctcaattggc aaggtaatgc
    19921 cctgcttttc aataatcatc aagagacgtt ctaaaccaag accaaagcca aatcctggag
    19981 tctcaggccc accaaaataa cctactaaac tatcataacg tccacccgca cagatagtta
    20041 agtcagaacc ttccacagac gtgatgaatt caaaaatagt gtggttatag taatcaaggc
    20101 cacgcaccat attggtgtca atcacataag gaatgtcaag tgcttcaagc atatctttga
    20161 ccgcctcaaa gtgcgcctga ctttcctcat ctaagtaatc caaaatagaa ggcgcttttt
    20221 caacggctag tttatcttct ttttctttag aatcaagcac gcgcagtggg ttttcatcca
    20281 agcgacgttg actatcttta gataattgat cacgcattgg tgttaagtag tcaatcaagg
    20341 cttgacgata agctgcacga ctctcaggac tccccaaact atttaaatga agggtgacat
    20401 ccttaatgcc caatttttca aagaggtgat aggccatcgc aatggtttca acatctgttg
    20461 ctggattagc agcgccgaaa cattctaccc caatctggtg aaattcacgt aaacgaccag
    20521 cttgaggacg ttcgtagcgg aacatggaac cgatataata aagtttgacg ggtttttgga
    20581 cctctggcgc aaacaattta ttttcaacat aagaacgcac cactggagct gtaccctctg
    20641 gtcgcaaggt aatgtgacga tctcctttat catagaaatc atacatttcc ttcgtcacaa
    20701 tatcagtcgt atcacccaca gaccgcgaga ttacctcgta gtgttcaaac ataggagtac
    20761 gaatttctcc ataattgtat tggctaaacg tatcacgcgc aacagattcc acatactgcc
    20821 atttcgcagc atccccaggc agaatatcct gagtcccttt tggtttttga agtttcataa
    20881 gtttacctct ttgattagtt ttctctttaa acattctacc attttttctt atattttaaa
    20941 caagcatata tcatttgctt tagtttgata gtattttcac catgaaattg taaaaataaa
    21001 aagttttgtc aagtaacttt actttacaaa aaagatatgt tatcatagtg aagttgatga
    21061 aaatcaaaac ttacacatcg aaaggaagaa caagaaaatg gcagtacctg cacgtcacac
    21121 gtcaaaagcg aagaaaaaca aacgtcgtac acactacaaa ttgacagctc catctgtaca
    21181 attcgacgaa actactggag attactcacg ttctcaccgt gtatccctta aaggatacta
    21241 caaaggacgt aaaatcgcta aagctaacga agctaaataa tagaagggag ataccatgcg
    21301 cgtaaatatt acacttgaac ataaagaatc tggtgaacgc ttgtacctta cttcaaaaaa
    21361 caaacgtaac actccagacc gtcttcaatt gaaaaaatac tcaccaaaat tacgtaaaca
    21421 cgttacattt acagaagtta agtaaggggt tcactacacg tcattagacg tcaaaacatt
    21481 gattttaagc gatttttgaa ttttttgaag ttcattacat tgcaatataa atcaataaaa
    21541 actctacctt ttactctacc ttttttagat gaatctatca tttggatatt gaagttaggc
    21601 cctgttatca tttcgatggc agggcttttt aatatttggt acactaactc cttatctata
    21661 ttttggtgga gctgaagttg acatctataa agtttaatgt taatatacat tcaaaaatac
    21721 atttgaatga ggtgttttat gattcaaaat gttgttactt caataatcct gtattctggg
    21781 acagccgtag acttacttat tatcctaatg ttattttttg ccaaaagaaa aagcagaaaa
    21841 gacatcatta acatctattt aggacaattt ctaggctctg ttagtctaat attgctaagt
    21901 ttgctttttg catttgtctt agattatatt cctagtaaag agattttagg tttgctcggt
    21961 ttgattccaa ttttcctagg cctcaaagtt ttgcttttag gagattctga tggagaagct
    22021 attgccaaag aaggtttgcg caaagataat aaaaacctga tttttctagt cgctatgatt
    22081 acttttgcaa gttgtggtgc tgacaatatt ggtgtctttg tcccgtattt tactacctta
    22141 aatttagcga atttgatagt ggctttactt acctttctag tcatgattta tctcttggtt
    22201 ttttctgccc aaaaattggc acaagtccct tctgttggag aaattttgga aaaatatagc
    22261 agatggttta ttgccgttgt ttatttagga ttggggatat atatcctgat tgaaaacaac
    22321 agttttgaca tgctatgggc tgtgttaggc taggagaaaa tattatgaaa aaagatagta
    22381 tctgccaagt gaatgttata aatcaacaaa atgttacaac cgcaacgaac taccttgaaa
    22441 aggaaaaagt ccaaaaatca cttcgtattt tatcaaagtt taccgataat aaacagataa
    22501 atatcatctt ttatctcctt actgttgaag aactctgtgt ctgcgatata gcctgtttac
    22561 taaatctcag tatggcatct gcctcccacc atcttcgtaa actagccaat caaaacatct
    22621 tggacactag aagagagggg aaaattatat attattttat aaaagatgag gaaatcagag
    22681 atttttttaa tcaactagga taacaactat ttttaccact tttccatgtt tatagagggc
    22741 ttatctatga aattttttga tgaaaattac tcacaagaaa tacctactcg tatcaaatgt
    22801 ttaagaaaaa agtataattt aaagtaaagt gacctaggta atgcaggtca agttagccaa
    22861 gttgaaaagg gaaagcgaca agttaccgct tcaatattgc tttatttgaa tactcaaacc
    22921 gactcggact ataaagaaat tatttttgga gatattgcca agtttgttga aaatatgttt
    22981 taccactact tcagctctat tttatttaga gatttggaaa ctgtagataa aagaatgtat
    23041 tctttttcgg acgatgactt aatttcaata caatccagct gtcttagact ttccaagaca
    23101 ttcgcaaatt tcaatattca aagaaaaaat tttttggctt ctgatgaaac tgaaatggat
    23161 acttttcaca agaaagatga cattgacatt actgttggtg aaaaaagtta taacctcgct
    23221 agaagtttta gaaccagtac catcaatgaa ttgactgtct ttaattttga agaaatgttt
    23281 gatattattt ggttgatgtt aggggataat ttaattaaat catttgaagt taatgtctgt
    23341 ggtatcctat ttgaattaga cggaaatggc ataccctcaa catttaggca agaaaacatt
    23401 gatcccctca tcaataaatg gtggtatgat aatgtttcga cagaaattat ccctaaccta
    23461 ataaaaaaac tcaaagaaaa tccactattt aatatcggat tcctggttga tgatattcta
    23521 gaacgaatgt ataaagaaaa tatcccaaaa tcttacctta cgtccgtccc gttagttatt
    23581 tccaaaaaag caaggtcaac tttatcgatt aagtcaaacg gaagtcaaaa aatagataaa
    23641 tcaaaatttg cacagatttt gtccctttag agacggatga cttacacatt caacgtggat
    23701 tattcttccc ttggagaaag gggatttcag aacgcttggc gattcctgat ttagataaat
    23761 tttcatctag cttacaacag gggaaaattc ctgtcataaa gcacttcgaa ctcaatttag
    23821 ataaggggag tcactgggct attgctggaa attcaggttc tgggaaaccg tacgctctca
    23881 cttacttctt gagtgtcctg aaacctatgt ccggcctaat tatcattgac ccaaaattcg
    23941 atacccctag ccaatgggca agagaaaata aaattgccgt tatccaccca gtagaaaacc
    24001 attcaaaatc tgatttcgtt tcacaagtca atgaacaatt aaaccagtgt gcaactctca
    24061 ttcagaaacg acaagctatc ttgtatgata atcccaatca tcaatttacc catctaacta
    24121 ttgttattga tgaagtcctc gctctatcag agggagtcaa taagaatatc aaagaagctt
    24181 ttttctccct actatcacaa attgccttgt tgggacatgc tactaaaatc catctattct
    24241 tgggaagcca gcgttttgac cataacacta ttcccatttc agtgagggaa cagctaaacg
    24301 tattattgca aattggaaat atcaatcaga aaaccactca attcttattt ccagacctag
    24361 atccagaggg gattgtcatt ccaacaggac acggaacagg tatcattcaa gttgtcgata
    24421 atgaacactc ctatcaagtt ctacccttac tctgtccaac ctactatact aagcgaggta
    24481 tcctatgacc actaaaacct acttcatgag aagcttcaat ctcatattat acttactgct
    24541 tattgctcca atctgctatg tgttcggttg gctgttcaat cttgtttcag ttcaattatc
    24601 taccgtcaca tttgtcaatc tggatacggt taaaaacgtt actgatacca ttagttctgt
    24661 atgttatgga ttcgctctta tttctttatt tctagcctta ttatctggat taaagatgat
    24721 acaacgcttg aatacagata gccttgggaa ctactgccaa tctatttatc gcacctttct
    24781 actaagacac ttccttttcc agcgtgaacg agtacagaag gtaagcaact ttgaacacca
    24841 gaccgttacc actatcaatc caatccataa cgggtttaac cgagctgtac gtaagtgtat
    24901 cgtagatata cgaaaagatg ccattactgt atttctaaaa gtttctagag acccaacagg
    24961 ggcaaaaaat cctaaaggat acgggagtac aactgaaaga agagattgtc atccaacaca
    25021 cagactatta tttctcttct cctgttcgag ttcgtaacca attgtggttt attggtcaaa
    25081 agcgttaatt ccttggggct gtggcttgcg ttaagcaaaa gccagacagc ccctttttta
    25141 tattcttatc tatcatgacc tattggggtt actacgacaa cgaaagttag aagctgtggg
    25201 tatttattta tcttgaaaag attgctgaac taacgcaata actactctac cattcactct
    25261 accttttatt aagcaactat caataaatat tgatacaata aggtttataa cagctaaaat
    25321 agaaaatact taacctttac agaagtaaaa taattgagat gagaaaagcc tatgaaatga
    25381 acgtttcaaa ggcttttttc gtgttaaaaa aaacaaatga aaaaacaaaa tagagagtag
    25441 ggttattaac actgtcaatc ctgtgtacgc aataacaatc catgcttttt gataaggata
    25501 ttttgctttt tctttaatct tatcaatctg atctaagctc tcaccctttg ctatagcttc
    25561 aagttatcgg taagtctgaa catcatatgt ctttttaaat cgctcaattc ttaaggcgct
    25621 acgcatgatt atcaaccata agatagcaac cggaccatat ccccaccaac ctaaccaaga
    25681 cattatagga taaatactga tagcaattag gagtatccca aataacataa tatgcgtatt
    25741 cctatcacat tgtttaatct cctcatcctt aataattaaa gtcatttttg ggatatcttc
    25801 tgctattagt tgctctaaag gaacctgtaa ggacttactt aacatcaaaa gattttgcag
    25861 gtctggatag cttttaccgt tttcccagtt tgagatagtc ttcttgaaac atacatcatt
    25921 tcagcaagct cttcttgtga catctgtaat ttttttcaat aataaggtaa ctggttttta
    25981 aagcccataa taaatctcct ttttaatagc tactataatc cttcttcaat aagtttacta
    26041 tcaaaagtct ttgacctaag ctttttttcg tttatctttt tgataattat cgtaaggttt
    26101 acagtctttg taaattttat ttacaacttt gacaatcaaa cttgacttga tcacaaagac
    26161 atggtgttta aggaaaatat cttcaaaatt gaatgtatta tttattagga acaattattt
    26221 tagtagggat atgcagcttt gtgtcagcaa ttctttaaat ttatgataca ataaaatcat
    26281 tcttttcagg aggcaacaat ggtttcattt atttcaagag tttttaaagg catgattatt
    26341 gcactaggtt ttattttacc tggtgtatcc ggtggtgttc tcgcagccat tttaggaatc
    26401 tatgagcgag tgatttcctt tttagctcat atgagggata actttattga aaatgtctta
    26461 tttttcttac cagtaggaat tggtggtatt ttaggtattg ctctcttttc tttccccgtt
    26521 gagtttttgc ttaagcacta tcaagttatc gtcttatggg gatttgctgg cgctattgtc
    26581 ggcactattc ctagtctgat taaggagtca accaagcagt ctcaaagaga caaagttgac
    26641 tggctatggc tagtccttac ctttgttatt tcaggactag gtctttactt cttaaatgac
    26701 ttaatcggta ccttaccagc taacttttta acctttattt tagcaggtgc cttaattgct
    26761 ttaggagtac tggtccctgg actaagcccg tcaaatctct tacttatctt aggactctat
    26821 ggtcctatgt taataggatt caaatctttg gatttattag ggactttctt acctattgct
    26881 atcggaggag tcctagccat cttggctttt tctaaaagta tggattatgc tttacagcac
    26941 catcattcaa aagtttacca ctttatcatt ggtattgtat tatccagcac gctattaatt
    27001 cttattccaa atagtagtag tcccgaatcc atttcctaca gtcatgcagg tatcttaacc
    27061 tggcttatga ccgttgtgtt atttgctctt ggtatttggc tcggactttg gatgagtcaa
    27121 ttagaagaaa aatacaaata acctttacag gttgttgaca aaaagttgac gccaacaaac
    27181 tagtgctcta tctcccctta gatttttcaa tatctaaggg gtttttcttt gcaattgatt
    27241 catcatttag aatatcggtt aaacacttag taaactgggc agtcattctc catatggttt
    27301 cttctagatt ttcataaaac ggaatactac ggtactcttg actaaattgg tagtatttcc
    27361 cattacgaat acggtcaaaa ggaaaatccg ttgtctcaat aggagtggct tctaaacgat
    27421 aatagacagg atcagtgaca agtagctgac gtaaaggtac tataaagacc ttgtcaactt
    27481 cttcgttagg ctgtatgctt ttccagtcat caacgactaa ttgaccaacg aaacaatgaa
    27541 tagttctaga agactgtact aaataatcaa tttcacccca tagctggatc tgggacgcat
    27601 caacagtcaa ttcctcaact gtttctcgga tagcagcttc ttgaagtgtc tcctgatttt
    27661 ctacttgtcc ccctgggaaa gaaacttccc ccggttgtga aatatgctga cttctgactt
    27721 catataagac atgccagtca tcattgacaa gaataagagg taaaaatacg gcgtaccgct
    27781 tctcctctcc tagtggtttt gcctgatact gttttaataa gtccttcata gccttcccta
    27841 atttctcttt ccgttaatct tatcttcatc ataaccaatc ctagcttttt ggtcaactta
    27901 ttactcctag ttagtgattt ttgatatata tgttattttt ttatatataa aatattgaca
    27961 tatcaaaaaa ctaagcttat actaaatatg taaaataatt atatataaaa tttttatata
    28021 tgaaaggagc ctaaaatgta ttttccagta tcggctacct tgattgaatt tctgatttta
    28081 gccattgtcg aaaaaaacga ttcttacggt tacgatatta gtcaaaccat taaactagtg
    28141 gctaatatca aagaatccac cctctatcct attcttaaaa aattggagaa ggcaggtttt
    28201 ttgacaactt atagtcaaga acatcaggga cgaaagcgta aatattatgc tgtcacttct
    28261 tcggggagag cacagctgat ttttctaaaa aaagaatggc agagctataa atttgcctta
    28321 gacgggatta ttgaagggag cttaagacat gacaaggact gagtatctag cagaactaga
    28381 taaatacttg cgcaaactac ctagagaaga ctaccatgaa gcgatggaat attatattga
    28441 atattttgat gaagctggtc ctgacaaaga aagccaggtt atcgacgatt taggaaatcc
    28501 taaggaagct gccagtgaaa tcatttcaaa tgttctagga aaacacttgg caactcccga
    28561 gaaaactccc aaaaatcggg caacaattat tggattaacc attttgtccc tctttgctgc
    28621 tccgattgct ttacccgtat tgctggcgtt gattctcttt attattgcct gcctaatgct
    28681 cgggctcaca gctatctttg ccgcctacat ttttgggctt gcaggtattc ttgtcgcagg
    28741 agtgactctg tttgaaagct tgaccttgat tggctcatct attcctgcac aagctatggg
    28801 catcggcagc gccttgttgt gttttggtgg tggtcttctt atttggatta ttgccacagc
    28861 aatccttcgt ttttcaggac gggcttttgt tgcctttatt aagtggatca gtaataagaa
    28921 aggagctcaa gcatgaaaaa tatctcacgc aaatgcttta taaccagtgt gttatgtatt
    28981 attctaggag gcattcttct aggggctggc tatgcaactg gaggacttca ggacattaaa
    29041 caccaaacag ctcccaaaaa ggtcatcaaa acatttgatc aaataactgc tcttgatatt
    29101 gacagttctg cctcaactat tacagtagag acaggacccg ttcaaagacc aacagtgacc
    29161 tattacacac atcctaaatt tattgaccct atcgtcacaa cagtaacagg taagacccta
    29221 tctctttcgc aaaaacctaa agacgttgtc atcactggtg gaattgaaat tttaggtttt
    29281 actctcaata atagtcgtca agagaagaac taccgttcta ttaccattac tgttcctgaa
    29341 aaaactagcc tcaatgaagt taagggaagt aatgtcccac ataccacttt gtcaaatcta
    29401 actgtccaag atatgcaatt cgatggcaat cttactcttt tacataccaa agtcaagaaa
    29461 gctactatca ctggtatgtt ggaagccact aaaagtcagt taacaaatct cgagttaaaa
    29521 gctgactatt ctttttcaaa cctgactgat tctagtgtgg aaaatgggac catcagctta
    29581 ggaaatggac aactaactac taaagatacc actctaaaag ctgtcaatat tcaatcatta
    29641 caccctggtg gtatagaagc cgagagaaca acccttgaaa atgtgacctt cactgtttct
    29701 aaaagcaaag aagaagagga gaacgactac tatgacaatg atgctatctt caccgctcat
    29761 gcccttaccc ttaaagggac taatactatt actggtggtg atattgatgt tgacataacc
    29821 ttgacaaaag caaaggccat cgcctacaga gcaaggaccg aaaatggtaa agtctccctt
    29881 ggctcacagc tgacaccagc taagattggt aaggaatcaa cttcagatgt tatttcttat
    29941 gtggctgaga ataaagcagc tactggaaat ttaacggtta atctcaataa gggagacatt
    30001 actatcaaat gatcttaaca agacaataaa aaacttgaca gaaattgtca agttattgtc
    30061 aaaataagac aaaaaacagc atctagtgta actgccttag atgctgtttt ttttgaggtt
    30121 attttattta gactgttttc ttaggacgat aaatgagtag tgctaatacc ataaatgcca
    30181 gtaagaaacc agttaagact ttcacttcta ctccaatatg acctgataat gaaatggttt
    30241 gtcgtaaacc agataccaca taagtcattg gtaagaaagg atgtaacttt tggaagaatg
    30301 ctccacttaa ctcaatgggg taagagccac ctgaagagcc aacctgaagc aataacatga
    30361 ccaaagaagc aaaagagcca tatcgatcat cccaaccgac caaagctgtg acaagagcca
    30421 taaacgtcca accacttagc ataataaatc ctaaggtttc cataccataa cgggcttcaa
    30481 accctaataa ttgaatagct aagtagagaa caatggatcc catagtcgaa ataaaaccat
    30541 taataacaaa tttttgttta gcccaatccc atttatcttt gaccggacga ccagataaag
    30601 aattagcaaa aatgacgttg gttgaaaggg ccacaaccat tagagaaaca gcaatcatat
    30661 aaggtgccat cccgatccca ttcgtcttaa caccatcttt gtctttctca tttaacacaa
    30721 gaggttttgc gacagcttta gcatttttat cagtcacaga aacaagcgat aactgctgag
    30781 aggctttggc taaggaacca tttaaggttg ataatcctgt tgataattca gtcaatccgc
    30841 tcgttaattg atgaccaccc tgactcaatt gagaactact atcagctagt ttagtagcac
    30901 cctctgataa ttgatggcta ccatctagta attctccgga cttggatgac aaggcattgg
    30961 taccttctga gagttttatt accccagaac caatggcagt attatacctg tttaattgtg
    31021 ctaatcctgt tgtcaattga ttacttcctg gtagaacttg ttgatttaag ctaccattta
    31081 cctttgctaa tcccgttgat aattcagtta aagcagaact tgctcccggc aaagcttgat
    31141 tggattgatt agcaatctgt gcaacagctt ccttaagttg ctccaactgt tttgactgat
    31201 cttcttgaga gagagactgt aaacttgttg acaaagtttg aacagaactt aaaatagttt
    31261 gggctgcaga tacggtctga cttttatcag attgactgag ggccgcagct aactctcctt
    31321 gttgttcagc agttaatgat tggtaaacgc tagtagcttg gagagccgat aattcttcat
    31381 tctgagcggc agtctcttca gcaatgactt gtttggcagc ttgagcgata gctcctaagc
    31441 tattacctaa ctcatcagca ttaaggttag ggggttgcaa tgttgatagc tctgtattta
    31501 gttgctgaat gccttgattt aggactggta gtcctacaat taaggattga attcccttag
    31561 ctttctcgtc agaaagtgtt gttgcttgtg tcaactgtga aagaccctga ttaagctgag
    31621 aagctccctg ggataaccta gaaaccccat tcagataatt ggggatgtcc gttgataatg
    31681 ttcctaaccc attcttgact tggttgacac catctgtata ggtagtcaaa cctgatgtca
    31741 atcgaccagt accttgttga aactgttggc tagcacccgt taaggctgct aagttcgtcg
    31801 aaagtgtttg actccccgcc tgagcggtct tcgctcctga agcaagtgcc tgacttccag
    31861 ctgaggcttc ttttaatcct gattggaggt ctgtcatact cctaaaaact gctgaggtgt
    31921 aaatcttcgt aatgttttgc gaaacagact ctttcagttt tgtcatcgct gtttcaccca
    31981 tcttagcagc aaccattcca tgtcctttac tagtttggta acggatagtt agtttttggg
    32041 gttcaggatt taataaggtt gttgctcgct gagaaagatc ttcgggtaaa gtaatgacca
    32101 tataataatc acctttttta agaccctctt gagcttgctt agctgagaca aaatgatact
    32161 ctaaatcttt acttttagac atcttgtcca ccatatcatt cccaattgtc aatgacttat
    32221 cagctctctt tgcaggctta tcatgattaa caacagcaat gggaaggtca ttgacccgac
    32281 cataaggatc ccacattgag cctagaaagg ataaattata taaggcaggc actagggcca
    32341 caccaatcat tgtaatcatt aattttggat ttttaataag tgttttcaat tcttctaaca
    32401 tattttctcc taaaatggac atactgttc
//
LOCUS       DAUGOH010000018        31134 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUGOH010000018 DAUGOH010000000
VERSION     DAUGOH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31134
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.018"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            6..1352
                     /locus_tag="VH957_000939"
     CDS             6..1352
                     /locus_tag="VH957_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8558858.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLETYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            1349..2632
                     /locus_tag="VH957_000940"
     CDS             1349..2632
                     /locus_tag="VH957_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8558859.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSVIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            2636..3376
                     /locus_tag="VH957_000941"
     CDS             2636..3376
                     /locus_tag="VH957_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8558860.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            3916..4275
                     /gene="rnpA"
                     /locus_tag="VH957_000942"
     CDS             3916..4275
                     /gene="rnpA"
                     /locus_tag="VH957_000942"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEQ8558861.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            4241..5068
                     /locus_tag="VH957_000943"
     CDS             4241..5068
                     /locus_tag="VH957_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8558862.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLILMPLFNMQIKSSQKMQDIQPELRELQRKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            5080..5994
                     /locus_tag="VH957_000944"
     CDS             5080..5994
                     /locus_tag="VH957_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEQ8558863.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLPRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINRQNAPAVNSADVEPEEIKATQRLEAED
                     TKVVPLMSEDSPAQIPSNLAETVTETKAQQPSIPVEESEVPQDAGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            6308..6442
                     /gene="rpmH"
                     /locus_tag="VH957_000945"
     CDS             6308..6442
                     /gene="rpmH"
                     /locus_tag="VH957_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEQ8558864.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            6716..7420
                     /locus_tag="VH957_000946"
     CDS             6716..7420
                     /locus_tag="VH957_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEQ8558865.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            7469..8788
                     /locus_tag="VH957_000947"
     CDS             7469..8788
                     /locus_tag="VH957_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8558866.1"
                     /translation="MNMKKLASLVMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTKEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAISNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            8892..9779
                     /locus_tag="VH957_000948"
     CDS             8892..9779
                     /locus_tag="VH957_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8558867.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLMNTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            9792..10622
                     /locus_tag="VH957_000949"
     CDS             9792..10622
                     /locus_tag="VH957_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8558868.1"
                     /translation="MTKKKLTASDILTTVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            10642..11097
                     /locus_tag="VH957_000950"
     CDS             10642..11097
                     /locus_tag="VH957_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEQ8558869.1"
                     /translation="MFYDRLKNISRYRGIHPHLDAAITFLQTTDLRQLAEGKYPILGE
                     KVFAVIQRNQLSKADNSLLEYHKRYADCHLLLAGNECIRYGIGNQAEVVPFEQEADIG
                     FVTCDRTYDLDLVDDSFAYFFPNEPHQPNNFNQAGEAVTKCLIKVLMAD"
     gene            11141..11803
                     /locus_tag="VH957_000951"
     CDS             11141..11803
                     /locus_tag="VH957_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEQ8558870.1"
                     /translation="MTSKKQGLLHSLFNLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSRFKHYFKSGMRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVRKELSLSTLFKRSFLLAGLFFP
                     WSFAFLALICLTIFSLQLSLLTLFGGVALLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            11815..12729
                     /locus_tag="VH957_000952"
     CDS             11815..12729
                     /locus_tag="VH957_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEQ8558871.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYSVADYWNAISEAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDGHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIADKDLEKAKALQYTINEIISVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLSELVEEDRVICQRAAALINQAKETF"
     gene            12751..13689
                     /locus_tag="VH957_000953"
     CDS             12751..13689
                     /locus_tag="VH957_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8558872.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(13800..14630)
                     /locus_tag="VH957_000954"
     CDS             complement(13800..14630)
                     /locus_tag="VH957_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEQ8558873.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEELLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            14915..15706
                     /locus_tag="VH957_000955"
     CDS             14915..15706
                     /locus_tag="VH957_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEQ8558874.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHEAEELALAQEMGVAYHNVV
                     GFDQATISGALALADQYPHVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYHWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKETTANAKRVFKLD"
     gene            15678..16268
                     /gene="rnmV"
                     /locus_tag="VH957_000956"
     CDS             15678..16268
                     /gene="rnmV"
                     /locus_tag="VH957_000956"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEQ8558875.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHARFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            16382..17254
                     /gene="rsmA"
                     /locus_tag="VH957_000957"
     CDS             16382..17254
                     /gene="rsmA"
                     /locus_tag="VH957_000957"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEQ8558876.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVED
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            17680..18552
                     /gene="rsgA"
                     /locus_tag="VH957_000958"
     CDS             17680..18552
                     /gene="rsgA"
                     /locus_tag="VH957_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEQ8558877.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            18562..19224
                     /locus_tag="VH957_000959"
     CDS             18562..19224
                     /locus_tag="VH957_000959"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEQ8558878.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            19217..19849
                     /locus_tag="VH957_000960"
     CDS             19217..19849
                     /locus_tag="VH957_000960"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEQ8558879.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVPQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMLTYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            19851..21122
                     /locus_tag="VH957_000961"
     CDS             19851..21122
                     /locus_tag="VH957_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEQ8558880.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEEINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLNASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            21112..22050
                     /locus_tag="VH957_000962"
     CDS             21112..22050
                     /locus_tag="VH957_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEQ8558881.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVEEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            22316..23155
                     /gene="purR"
                     /locus_tag="VH957_000963"
     CDS             22316..23155
                     /gene="purR"
                     /locus_tag="VH957_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEQ8558882.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            23146..25767
                     /locus_tag="VH957_000964"
     CDS             23146..25767
                     /locus_tag="VH957_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEQ8558883.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINNLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPSLTGVKPLSYSKVETTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESR"
     gene            25975..26388
                     /gene="rpsL"
                     /locus_tag="VH957_000965"
     CDS             25975..26388
                     /gene="rpsL"
                     /locus_tag="VH957_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEQ8558884.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            26409..26879
                     /gene="rpsG"
                     /locus_tag="VH957_000966"
     CDS             26409..26879
                     /gene="rpsG"
                     /locus_tag="VH957_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEQ8558885.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            27363..29441
                     /gene="fusA"
                     /locus_tag="VH957_000967"
     CDS             27363..29441
                     /gene="fusA"
                     /locus_tag="VH957_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEQ8558886.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            29781..30791
                     /gene="gap"
                     /locus_tag="VH957_000968"
     CDS             29781..30791
                     /gene="gap"
                     /locus_tag="VH957_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEQ8558887.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINSAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(31017..31133)
                     /locus_tag="VH957_000969"
     CDS             complement(31017..31133)
                     /locus_tag="VH957_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEQ8558888.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
BASE COUNT         9534 a         5682 c         6601 g         9317 t
ORIGIN      
        1 aaaaaatggc taatagcgaa tatatgtttt tattattatc aattattgtc tattatatga
       61 caaaaattta tattttttcc tttctatctg atatcacatt accagtttgg aaacaactaa
      121 cgattttggc tttagcccta tttttcaatc agttcccgta tttgtcgcca ttgctaattg
      181 atcctctatt atttttagtt gttttaaggc aagaaaccaa gcaattattt tctttgaaag
      241 ctcttttttt ggctgttgca cctagtgttt tggtggattt gctatctcgg tttatgggta
      301 caatcgttat cccctatctt tttttgtcga gtggtattta tctgggtcat attatctttg
      361 acttgcttgc ttatctgctg atttttccaa gttttgctat tattaattat atgattggaa
      421 aagattacaa gatgatatgc caatccggat attcgaaacg atcgcataat ttttatcaaa
      481 cattgctgat ttttgttttg gtttattatg tggacatttt tgtcatttta ggatttacgg
      541 accccttttt acattttcat cattctcttt ttgttcccac accttataag ttattgtttt
      601 tgatgtttat acttctttta gtttatcttc tatcttattt taatcatagt tctaaagaat
      661 accttaaaaa tgagttgaga agagaacaac aagcttatat gactaactta gagacttatg
      721 ggaaacatct tgagaaactc tatcgagatg taagagcttt tcaaagtgat tacctgagcc
      781 gtatagagcg tttaggtcaa gccattaaga gtgaatccat tactcagatt caagatattt
      841 atgcccaaac ggttcatgaa gctaacgact actgggatga taaacactat aatatctcga
      901 agcttaggaa aattaatatc tcatcgatta agagcttatt gtcagctaaa attatcagtg
      961 cggaaaaatc aggtattgat ttgaatgtgg aagtgccaga taatataaaa gagacttaca
     1021 ttcctgagtt ggacttacta ttgttgatgt ctattttttg tgataacgcc attgaggcag
     1081 ctcttgaagc acagcaacct catatgtcaa ttgcttactt tttgttagat gactatcaga
     1141 tgtttgttgt gacaaatacg actaaaaaaa aggtagacat taacaagatc tttgaagaag
     1201 gctattcttc aaaaggttca gaacgtggta tcggcctttc taatgcgcag cgtattctca
     1261 aaaagtatcc ttatttatcc ttgcggacta aaagttttga taaggaattt agccaaacct
     1321 tgaccatgcc aaaggaggag gtggatagat gatggttata tacagtatgg ctttattcta
     1381 tgctaccatc tttattaaca gctgggtcat ttttgcaaag gtttctgcta ttaaactaag
     1441 ctggaaacgg gttagcgtta taggcattag ttttgtaatt gctaatatga tatttgacaa
     1501 agtcattttg attgaccaac tgttttttat tattgttagt ttgttaagtg ctccgaaaaa
     1561 gaaattattt gagcatatgt ttaatggttt ctttactatc ttgattgtcg aattactgtt
     1621 tcgcgtcatc ggatctttct ttttaccagc tgtcttagga tttagcattg gtcaaattaa
     1681 taataacctt aagcttttag agttatgtta tctttttgta ttaccaatat tttatctgtt
     1741 tagctacatt ttcagtattg acttaagctt aataaggttt atcagtgaag ataagatgaa
     1801 aaagtgggta ttttggatga atactgccat gttttcttac tactttttcg cccatttttt
     1861 ggtaactgtg caaagcggat ttcttgcact atatttccag taccggtcta ttttagtatt
     1921 tatttattta gctattttta tttgggttat tgtgaaatta gatcgatttg ctaaagatca
     1981 gctgtcacaa aaattaacac aagcacaaaa tgaacgtatt gcgtatcttg aaaattacaa
     2041 tcaatcgatt gagcaacttt accgagaaat cagaacagtt aaacatgatt ctgaaaatat
     2101 tttaattagt ttaaaagata gtatcgatag tggtgatata gatctgatta ctagagttta
     2161 tgacacggtt attcagcaat cggcaacttc tatgatgcgc acaaattatg aaatatcttc
     2221 tttagacaat atcaaagagg ctgtgattcg cagcatcatg aattccaaat tgcttgaagc
     2281 tcagtatttg ggtattgaac tttatattga gattccagat gttatcgatc atttacctat
     2341 taagttaatc gatttaattg tactttttac tggactagtg gacaatgcta ttgagacagc
     2401 caaaggcagt agacgtcctt ttttatctat tgcatacttt aaacaagata acaagcaatt
     2461 atttattatt gaaaatagca caaaaaccaa tcgtgtggat atagccaaac gctttgatgc
     2521 tcagcagcag aactcagccc actttttgac tgttttagat agttaccccc aaataacgct
     2581 ttcgactaaa agtgaccatt atcgattaag acaattgtta gaaatgagat aaagtatgat
     2641 gaacattttt attcttgagg atgattttat ccagcagaca cgcatagaat ctatcgtagt
     2701 aggcatctta aaagagacta gaataccatg taatcagctt gaagtgttct cgactcctca
     2761 aaaattattt gagagtatcc aagaaagagg agaccatcag ctgtattttt tagatattga
     2821 aattggtgaa tatactcgtt gtgggcttga attagctgca gctattcgac aaaaagatcc
     2881 taatgccgtt attgtgtttg tcaccactca ttcagaattt gctcctattt cttttaaata
     2941 taaggtatcc gctctagatt ttattgataa agcaggtggt caaaaacagt ttaaagaaca
     3001 aatcgaagaa tgtatccgat atacttacga tatgatgtct agtcgtgagt caaaggacat
     3061 gtttttattt gagactccac agacaagatt aaaattgccc tataaggata ttttatactt
     3121 tgctacagcc acaactcctc acaaagtttg tttatggact cagacagaaa gattagagtt
     3181 ttatggtaat ctatctgaga ttcaagcagt agcaccgaaa ctttttttgt gccatagatc
     3241 ctaccttgtg aatctagata aggttgttcg aattgataag agtaagcagc tcctttattt
     3301 cgaaaatggt gattcttgta tggtatcacg gttaaaaatg aaatgtctgt ttgaacggtg
     3361 ggaggccctt cgctaaagtt aagagaggaa taacatttta ggacgaaaaa gcaacatttc
     3421 aggaaatgat gctcttattg aagtattttt cgctataata attaatgtaa ataaagattt
     3481 acgaagtcat gagtttatcg agcaatcaat ccccaattca atcaaaatat tgttttctct
     3541 ctctccataa acaaatagta tttttgatat gatggctcgg cagacaaaat gacgatgtca
     3601 gttgtctttg tttggatatc atattagctg attgtaaaat cagtattaaa gcccggcttg
     3661 ccgggttttt tgataggtaa atacagggat aagtagctga cgtcttgtgg attctgactt
     3721 tttatggttg ttttctgaag gttattcctt tgtcgaaaga agaactatac tacgaaaaga
     3781 tggagtgaca agaggcagtt gaagcacaaa aactagaaat agtacagaaa gaggcttaat
     3841 ctgaaagggt tagggctttt taatttttta ggggatgtgg tataatggta ataatttaga
     3901 tattggagtt aaattttgaa gaagacctat cgtgtcaagc gtgagaaaga tttccaagcc
     3961 atatttaagg atggaaaaag tacagcaaat cgaaaatttg tcatttatca tttaaataga
     4021 ggccaagacc acttccgtgt gggtatttct gtcggtaaaa aaataggaaa tgcagtcacc
     4081 agaaatgcag tcaaacgaaa gatacgtcat gttatcatgg cattagggca tcagctgaag
     4141 tcagaggatt tcgtggtgat tgcccgtaag ggtgtcgagt ctttggagta tcaagagctt
     4201 caacaaaatt tacatcatgt tttaaagtta gcacaattgc ttgagaaagg ttttgagagt
     4261 gaagaaaaac attaaaattg caagaatagt ccccttagtt ctattattag tggcctgtgg
     4321 tcgtggtgag gtaacggcac aatcatctag tggttgggac cagttggttt acttatttgc
     4381 cagagcaatt caatggcttt cctttgatgg ttcaattggt gttggcatta ttctttttac
     4441 ccttactatc cgtctcatac tcatgccttt gtttaacatg caaatcaaat caagccagaa
     4501 gatgcaagac atccaacctg agcttagaga attgcaaagg aaatacgctg gtaaagacac
     4561 acaaacgcgg atgaagttgg ctgaagaaag tcaagccctt tacaaaaaat atggggttaa
     4621 cccttatgct agtctcttac ccctcttgat tcagatgcca gttatgattg ccctattcca
     4681 agccttgaca cgggtatctt tcttaaaaac agggactttc ttgtgggtgg aattggcaca
     4741 acatgatcat ttgtaccttt taccagtttt ggcagctgtc ttcactttct tgtccacttg
     4801 gttgaccaat ctagcggcta aagaaaaaaa tgtcatgatg actgttatga tttatgtgat
     4861 gccgctaatg atctttttca tgggctttaa cttggctagt ggagtagtgc tctattggac
     4921 ggtctccaat gcctttcaag tggtacaact actgttatta aacaatcctt ttaagattat
     4981 tgcggaaaga caacgtcttg ccaatgaaga aaaagaacgc cgtcttcgtg aacgtcgtgc
     5041 tcgtaaaaaa gcaatgaaga gaaaatagga gtttaggtta tggtattatt tacaggaaaa
     5101 acagtcgaag aagctatcga aacaggactt caagagttag ggttaccacg ccttaaagcg
     5161 catatcaaag tcatttcaaa agagaaaaaa ggtttcctcg ggtttggtaa aaagccagcc
     5221 caagttgata tcgaaggtat cagcgacaag acggtttata aggctgataa aaaagccact
     5281 cgaggtgttc cagaggatat taatcgtcaa aatgctcccg cggtcaattc tgctgatgta
     5341 gaacctgaag aaataaaagc cactcaaagg ttagaagcag aagataccaa agtggttcct
     5401 ctcatgtctg aagatagtcc agcgcaaatc ccttctaatc ttgctgagac agtcactgaa
     5461 acaaaagcac aacaaccgtc aatcccagtc gaagaatcag aagtgcccca agatgctggt
     5521 aatgatggtt tcagcaaaga tattgaaaaa gctgctcagg aagtgtccga ttatgtgact
     5581 aaaattatct atgaaatgga tatcgaagct accgttgaaa ccagcaacaa tcgtcgccaa
     5641 atcaatttgc agattgaaac gccagaggcg ggacgtgtga ttggttacca tggtaaggtc
     5701 ttgaaatcct tgcagttgtt agctcaaaat ttcttgcacg accgctattc aaaaaatttt
     5761 tcagtatcct tgaatgtcca tgattatgtg gaacatcgaa cagaaacctt gattgacttt
     5821 acgcaaaaag ttgccaaacg cgttttggaa tctggtcaag attacaccat ggatcccatg
     5881 agtaacagtg agcgtaaaat cgttcataaa accgtttcat ccattgaagg ggttgatagt
     5941 tattctgaag gcaatgaccc taaccgctat gtggtagtca gtcttcaacg ttagatccta
     6001 aaagaatctt tggtagttag tttagctatc gaagattttt tgtatggcca gcttaaccgt
     6061 ttgttttact gatctcattg attattgttg ctattgataa ggtttcaacg gtaaggcaaa
     6121 ggaacagtgt caaagaagag acactttatg aaatgagcgg cctcttaaat gagagagaaa
     6181 ctgttgaaaa acgaaaataa atcttgacag tagaccctct ttaagataga atattatagt
     6241 atgtttagta actgatatca caaatagccg gctaaacgaa tacaaaatct atgaggaggt
     6301 attcactgtg aaacgtactt atcaaccaag taaaatccgt cgtcaacgta aacacggatt
     6361 ccgtcaccgt atgtcaacta aaaacggacg tcgcgtgctt gctgcacgtc gtcgtaaagg
     6421 acgtaaagta ttatcagctt aattgcaaaa aatacaacta aagtaaacca agagtgctcg
     6481 aggctcttgg ttttttaacg ttttctaatc ggaaatttgc aatgtataag tatggtgtca
     6541 actccttacc tttttatttg ttgtatgaaa gagcattcca aataatagaa aataatataa
     6601 aaaatgaaag tagattctaa aagtctcatt gctattgaaa gcgctttatt ttttgttata
     6661 ataactttgt gaacgttatt tttattaaaa ctaagaaaca caaggagtag aaactatgcc
     6721 tgataaacca accaaagaaa agctcatgga gcagttaaag ggtgggatta tcgtttcttg
     6781 tcaggctttg ccaggtgagc ctctctattc agagactggg ggtattatgc cactgctggc
     6841 aaaagctgct caagaagctg gtgctgtcgg catcagagct aattcggtta gagacattaa
     6901 agaaattcaa gccataacag acctaccaat tatcggtatc atcaaaaaag attacccgcc
     6961 gcaagagcct tttattacgg caacgatggc cgaagtggat caattagctg ccttaaatat
     7021 tgcagtgatt gctatggatt gtaccaagcg tgaccgacat gatggcttgg atattgctag
     7081 ctttattcga caagttaagg aaaagtaccc caatcagctt ttgatggcag atattagtac
     7141 ctttgatgaa ggactagtgg cccatcaggc tggcattgat tttgttggaa ccaccttgtc
     7201 aggctacacc ccgtatagcc gtcaggaagc aggtcctgat gtggcattga tagaagctct
     7261 ttgcaaagca ggcattgctg tcattgccga aggaaagatt cattccccag aagaagccaa
     7321 gaaaattaat gacttaggtg tggcaggtat tgttgttgga ggggccatta caaggcctaa
     7381 ggaaattgca gagcgtttta tcgaagcgct caaatcctaa tagtggttgt caaactagaa
     7441 acacacatca aaaaaaggag attttacgat gaacatgaag aagttagctt cattagtgat
     7501 gcttggtgca tctgttttag gactagcagc ttgtggcgga aagagccaga aagaggctgg
     7561 tgcaagtaaa tctgatactg ctaagacaga aatcacatgg tgggctttcc cggtcttcac
     7621 gcaagaaaaa gctgaagatg gtgtgggaac ctatgagaag aaattgattg ctgcctttga
     7681 gaaagctaat ccagaaatca aggtaaaatt ggaaaccatt gattttacat ctggtcctga
     7741 gaaaatcaca actgctattg aagctggaac agctcctgat gtcctctttg atgctccagg
     7801 tcgtatcatt caatatggta aaaatgggaa attggctgac ttgaatgact tgttcacaaa
     7861 agagtttacc aaagatgtta acaatgacaa attgattcaa gcctcaaaag caggagatac
     7921 agcttacatg tatcctatca gctctgctcc attctacatg gcgttgaata aaaaaatgct
     7981 caaagatgct ggcgtccttg accttgtgaa agaggggtgg acaacagatg attttgaaaa
     8041 agtcttgaaa gcattgaagg acaaaggata taacccaggt tctttctttg ctaatggtca
     8101 aggtggtgac caaggaccac gtgccttctt tgctaacctt tatagtagtc atattaccga
     8161 tgacaaagta accaaataca ccacagatga tgctaactct attaaagcca tgactaaaat
     8221 ttccaattgg attaaagatg gtttaatgat gaatggctct caatacgacg gttcagctga
     8281 tattcaaaac tttgcgaatg gccaaacttc ctttaccatt ctttgggcgc ctgcacaacc
     8341 cggcatccaa gctaaattgt tagaagctag taaagtggat taccttgaaa tcccattccc
     8401 atcagatgat ggcaaaccag aactagaata cctcgtaaat ggttttgcgg tctttaataa
     8461 caaagatgaa caaaaagtcg ctgcctctaa gacatttatc caatttatcg ctgatgataa
     8521 agaatgggga cctaaaaatg ttgttcgtac aggtgctttc cctgtaagaa cttcttatgg
     8581 ggatctttac aaagacaaac gaatggaaaa aattgctgaa tggacaaaat tctactcacc
     8641 atactacaac acgattgatg ggtttgctga aatgagaact ctttggttcc caatggttca
     8701 agccatctct aatggtgatg aaaagccaga agatgctttg aaagccttca ctgaaaaagc
     8761 aaacaagaca atcaaaaaaa cacaataagt gttcagaaca agtggcttct tttcacggca
     8821 catgtcaaat ggtcactgga aaggagcctt tcctttttta ggagagatta atagaaaaag
     8881 aggtatttca agtgaacgtc aataaattaa aaatgagaga gacgctcatc tcatacgctt
     8941 tcttagctcc ggtcttggtt ttctttgtga tttttgtctt gataccgatg attatgggct
     9001 ttgtgacgag ttttttcaat tattccatga cggattttac ctttgttggt tttgctaatt
     9061 atgctaggat gtttcaagat cccattttca tgaagtctct tatgaacacc ttgattattg
     9121 ttattggttc ggtacctgtt gtagttttct tttccctctt tgtggcggct aaaacctacg
     9181 acaaaaatgt agtggcgcgt tcgttttacc gggcagtttt ctttctgcct gttgttaccg
     9241 gaagtgttgc ggtgacggtg gtttggaaat ggatctatga tccgatgtca gggattttga
     9301 attatgtctt aaaatatgct catgtgattg aacaaaacat tagttggctg ggagataagc
     9361 actgggcttt gttagctatt attgttattt tattaaccac atctgttggg cagcctatta
     9421 ttctatatat tgcagctatg ggaaatattg ataactcttt ggtagaagct gcgcgtgtgg
     9481 atggggcgac ggaatttcag gtgttttgga atatcaagtg gccaagtctc ctgccaacaa
     9541 ccttatatat tgctgtcata acaaccatta attccttcca atgttttgct ttgattcaac
     9601 tcttgacgtc tggagggcca aattattcaa ccagtaccct catgtattat ttgtatgaaa
     9661 aggcctttaa gctctctgaa tatggctatg ccaacacaat gggtgtattc ttggcagtca
     9721 tgattgcaat catcagcttt gctcaattta aaattttagg taatgatgtg gaatattagg
     9781 aggatattaa gatgacgaaa aagaaactaa ccgcatcaga tatcttaacc actgtgatgc
     9841 tatgtgtttt gaccattttg tttatttttc cattttattg gattatgaca ggagcattta
     9901 aggctcaagc cgataccatt atgattccac cgcaatggtg gccaaaggcg cctactattg
     9961 aaaattttaa ggccttggta gtgcaaaatc cagccttaaa atggttgtgg aatagtgtct
    10021 ttatttcggt ggcgaccatg ttcttggttt gtggcacttc ctctttggct ggctatgctt
    10081 tggccaaaaa acggttttat gggcagcggc ttttgttttc gatttttatt gctgctatgg
    10141 ctttgccaaa acaggttgtc ctagtacctc ttgttcggat tgttaatttt atgggaatcc
    10201 atgatacttt ggcggctgtt attttgcctc ttgtgggctg gccatttggt gttttcctta
    10261 tgaaacagtt ctcagaaaat attccaaccg agttattgga atccgccaag attgatggat
    10321 gtggcgaaat tcgtaccttt ttcaatgtgg ctttccctat tgtcaaacca ggctttgcag
    10381 cgctagcgat ttttaccttt atcaatactt ggaatgatta ttttatgcag ttagtgatgt
    10441 taacctctcg ggaaaattta acgatttcac ttggggttgc cactatgcaa gctgaaatgg
    10501 ctactaatta tggcttgatt atggcagggg ctgccatggc tgcagtgcct attgtaacag
    10561 tctttcttgt cttccaaaaa tcatttaccc aaggcattac tatgggtgct gtgaaaggtt
    10621 aaatcaagaa aggtttctaa catgttttat gatcgtttaa aaaatattag ccgttaccga
    10681 gggattcacc ctcatttgga tgcggcgatt acctttttac aaaccacaga tttgaggcaa
    10741 ctagctgaag ggaaatatcc tattttaggg gagaaagtat ttgcagttat tcaaagaaat
    10801 caattgagta aagcggacaa ttcattgttg gaataccaca aacggtatgc agattgccac
    10861 cttttgctag ctgggaatga gtgcattcgt tatggtatag gtaatcaagc tgaagtagtg
    10921 ccttttgaac aagaagctga tattggcttt gtaacctgtg atcgaaccta tgacctagat
    10981 ttggttgatg atagctttgc ttactttttt cctaatgagc ctcatcaacc caataatttt
    11041 aaccaagcag gggaagcagt tacaaaatgc ttaatcaaag tgttaatggc agattaggtt
    11101 gatttggcag tgaaccaatt gatcgaaagg aagtgatggt gtgacgtcga aaaaacaggg
    11161 acttttacat tctcttttta atcttgatag taaatggatg agggctagtg cagcactatt
    11221 tgatttgctc gtgtttaatc tcttatttgt cttgtcctgc cttcctcttc tgacaattgg
    11281 ggttgctaaa atggctttgt atgcgagttt gttggattgg cgagaaggtc aagttagtca
    11341 gcttgttact acttatagct ctcgttttaa acattatttt aaaagtggga tgcgcctagg
    11401 tcttattgag cttttgataa tgagtatttg tgtcttagat cttttcttaa ttcgaaacca
    11461 atcaggccta gtttttcaag ggtttaaagt actttgcatt gctgttttat ttctggtagt
    11521 tatactcttt ttgtacgctt atcctcaggc cgtcagaaaa gagctttccc tatctacgct
    11581 gtttaagcga agctttttac tagccggact cttttttcca tggagttttg ctttcttggc
    11641 tcttatttgt ctcacgatat ttagcctaca attgtctctg ttaacgttat ttggaggcgt
    11701 ggctttgcta gctatcatcg gcatcagtag cctaacttac ctctacttga ttatcatgga
    11761 atcccttctt aggcgattcc cacttaataa tgacattgaa taaaggacat tactatgaca
    11821 gatcttacga aataccaagg cattattcct gccttttatg cttgttacga tgaccaagga
    11881 gctattagcc ctgagcgtgt gcgtgccttg acccagtact atattgacaa aggggttcag
    11941 gggctttaca ttaatggctc ttctggagag tgtatttacc agagcgtttt tgaccgtcaa
    12001 ttggtgttag aaaatgtcat ggcagtcgct aagggcaagc tgacgattat taatcacgtt
    12061 gcctgcaaca acactaaaga tagtattgaa ttggcagctc attcagaacg tttgggcgtg
    12121 gatgccattg cagctattcc gcctatttat ttccggttac cagaatattc agttgctgat
    12181 tattggaatg ctatttcgga ggcagctcct cacacagatt ttatcatcta taatattcct
    12241 caactggcag gggttgcctt gacgccaagc ctttataaga ctatgttggc taataagcgc
    12301 gtgattgggg ttaaaaactc atccatgcca gtgcaggata ttcaaacctt ctgtgcgatt
    12361 ggtggggacg gccatattgt ttttaatggc ccggatgaac aatttctagg agggcgcttg
    12421 atgggggctg ctgctggtat tggtggtacc tacggggcta tgccagaatt atttttaagg
    12481 ctgaaccaac ttattgctga caaggattta gaaaaggcca aggcccttca atatactatt
    12541 aatgagatta ttagtgtcct tgtttctgct catggcaata tgtatggggt tattaaggaa
    12601 gtacttcgta ttaatgaggg tcttgatatt ggttctgttc gttccccatt atctgagtta
    12661 gttgaggaag atagggttat ttgccaacgg gctgctgctc tgattaatca ggctaaggaa
    12721 accttttgat aagatgcgag gggataacaa atgaagcatt atttagcaat tgatattggt
    12781 ggtactgcta tcaagtatgg cttgatttct gaaacaggag acctgttgga aaaagaggaa
    12841 atggccactg aggcttataa aggtggtccc tctattttgg aaaaggtcaa gggcttggta
    12901 aagacctatc aagaccaaat ggatctggct ggagtggcca tttcttctgc aggaatggtt
    12961 aatcctgata agggagaaat cttttatgcc ggccctcaga ttcctaacta tgctggaact
    13021 cagtttaaaa aagagattga agagactttc gggttaccgt gtgaagtgga aaacgatgtt
    13081 aactgtgctg gtctagccga agctatttct ggtagtgcca aggattatcc tgtggctctt
    13141 tgcttgacaa ttgggacggg aatcggtggc tgtttattgt ttaattccca agtttttcat
    13201 ggtagtagtc attcagcttg cgaagttggt taccttcatt tgtcagatgg tcagtttcag
    13261 gatctggcat ctaccacagc tcttgttcaa gaggtggcct tagcttatgg cgatgacatt
    13321 agccaatggg atggtcgtcg tatttttgag caggctaaag cgggtgatgc gatttgtata
    13381 gcagccatta gtaagcaggt ggattactta ggacaaggta ttgctaatat ctgctacgtt
    13441 gttaacccaa atgtggtggt gcttggtggc ggtatcatgg cgcaaaaaga ttatttagct
    13501 gataaattaa agacagctct tgatagctac ttggtttcta gtcttgccaa gaaaactcag
    13561 ctgaagtttg ctagtcatgg aaataatgct ggtatattag gagcttacta ccattttaaa
    13621 caaaagaatg agcgatcctg ttcatttata actcttgaga aaatcgaaaa taatttagcg
    13681 agtagctaat cttagtggct gtgagtctat atgacgtgaa gagttcttgt ttaagtatac
    13741 tgggggaggt gaatgacgac cctttaaaaa gaaaacaacg ccctttttgc tattgtagtc
    13801 taaaggtcgt tattttcttt gtcaataata gtgtttttga agattttttc tttgtgcggt
    13861 ttgtcaatcg ctaaaacgta agcataaata atgtccatca taataagaag aggaaattgt
    13921 ggtgacacac gattcccata atgtagttgg tgggttgatg atacgggaat aatatctaag
    13981 gagtcgtcaa attcggtttg attatctgtt gttaagagga cagttttggc ccctcgctga
    14041 ctagcttgat gaagtgctgt gatgacagag tttgttttgc cagataaaga aaaaccaaaa
    14101 acaaggcaat tttcattgac gaggctattt gcccaagtaa aaccatcagt gtctgaataa
    14161 gcatcacaga ttaaaccaag tcgcataaag cgtagcttca tttctcttgc tactagtcca
    14221 gaagatcctt tgccaaagaa atagactcgc tcagaagcat cgatcagctt ggctaagttc
    14281 agtaattctt cctcattaac gagctcatag gttttattaa taagagcatc gtagtccatc
    14341 agcacgcgct ttgtcaattc taagtgaata gattggaaag tctcttgtga ttcttgaaga
    14401 ctgtgaaggt aatcaaaggc aaaagcacga taaccagtaa aaccacactt ttttgcaaat
    14461 cgagtcaagg cggcttgaga gatgtgtagt cgcttaacta tctcggatgc ggtcaactct
    14521 tgaggtgtca gatcggttgt aataaaaaaa tgagcaatcc ctttttctaa actggtcata
    14581 tgttccaatg atgcttcgat tttggtaatt aggcggtggt ttttaggcat agcaaagcac
    14641 actccttaca gtttaactat ctactagtat agcatagatc gctaagagaa ggtagcgacc
    14701 ctttttgtga tacagatttg ttcaacccac tttatttgag taggttgtag tatttttgag
    14761 ggcttatgta ggagccgact attaaaggtc atttgtcaaa aaagtagaaa atagacaagt
    14821 gtcagctagc aaagggtttt acgatcaacc taaacggcag aagttctcac caagttttct
    14881 gatgtggtta agatctttat gttataataa catcatgaca aataaagtag aaaaactaac
    14941 tatttttgat acccatacgc acctgaatgt agcagaattt caaggacatg aagctgaaga
    15001 attggctttg gctcaagaaa tgggcgtggc ctaccataat gtggttggct ttgaccaggc
    15061 cactattagt ggagcacttg ctctcgcaga ccagtatcct cacgtgtatg ctactattgg
    15121 atggcacccg acagaagcag gctcttattc tgaagcagtt gaggagtcta tcgtctctca
    15181 attatcacat cccaaagtga ttgccctggg tgaaattggc ttagactatc attggatgga
    15241 ggaccccaaa gaggtgcaaa tagaggtttt taagcgccaa atgcaattag caaaagacca
    15301 tgatttgcct tttgtggtgc acacccgtga tgccttggaa gatacctatg aagtcatcaa
    15361 agcagctggt gttggccctc gtggaggcat catgcattct tactcagggt cattagagat
    15421 ggctgaacgt ttcattgaac ttggcatgat gatttccttt tcaggtgtgg tcactttcaa
    15481 aaaggctctt gatattcaag aggcagcgca gcacttgcct ttggataaga ttttggtgga
    15541 aacagatgcc ccttatctta caccagttcc aaaacgtggc aaacaaaatc atacagctta
    15601 tacccgctat gtggttgata aaatcgcaga gctacggggg atgactgtgg aagaagttgc
    15661 aaaagaaacg actgctaatg caaagagggt attcaagctt gactgaaaaa attaatattc
    15721 aagaggttct tgttgtagaa ggcaaggacg acacggctaa ccttcgccgt ttttacgagg
    15781 tggataccta tgagaccaga ggctctgcta tcactgaaga agatttagaa cggatcaacc
    15841 gcctaaatga cttgcgtggt gtcattgttt tgacagaccc agattataat ggtgagcgca
    15901 ttcgtaagct cattatggca gctgtgccaa cagctcgtca cgccttttta aaccgaaacg
    15961 aggcggttcc gagttctaag agtaagggtc gttcattagg ggttgaacat gccagatttg
    16021 aggatctcca aaaggcactt gctcatgtca ctcagcaata tgatgatgag tcttattttg
    16081 acattcgtca aacagacctg attcgtctag ggcttttaat ggcgtcagat agccgtaaac
    16141 gcagggaata cttgggtgaa aagctccgca tcggttatgc caacggcaaa caactgctca
    16201 agcgcctcga attatttggc attaccctag cagaagtgga agaagtgatg gagacatatg
    16261 aggagtaaag agtacaataa aatataacag ccccattaac tgaatggcgt gtcctggcaa
    16321 aaaagtttag gctagtggtt caaatgccaa aaagaaagtg atcataaaaa gaagagaata
    16381 tatgagaatt gcagattata gcgtgaccaa ggctgtcctt gatcgtcacg gatttacctt
    16441 taagaaatct tttggtcaga actttttgac cgataccaat attttacaga aaatcgttga
    16501 cacggctgag attgatcaga atgtcaatgt tatcgagatt ggtcctggaa ttggggcttt
    16561 gacggaattt ttggcagaaa atgctgctga agtgatggct tttgagattg atgaccgctt
    16621 ggtgccgatt ttggcagata ccttgcgcga ttttgataat gtgcaagtgg tcaatcaaga
    16681 tattttgaaa gctgatttgc agacccaaat caagcagttt aaaaatcctg atttgcctat
    16741 caaggtggtg gctaacctac cttactacat cacaacgcct attctcatgc acttgattga
    16801 gagcaaaatt ccattccaag agtttgtagt catgatgcag cgtgaagtgg cagatcgtat
    16861 ttctgcggag ccaaacacta aagcttatgg ttccttgtcc attgcggtac agtattacat
    16921 gactgccaag gttgccttca ttgtgccgcg taccgtcttt gtacctgcac caaatgtcga
    16981 tagtgctatc ctcaaaatgg tgcgtcgcga ccagcctttg attgaggttg aggacgaaga
    17041 tttctttttc agagtgtctc gtctcagttt tgttcatcgt cgcaagaccc tgtggaataa
    17101 cttgactagc cattttggca agtctgaaga catcaaggct aaacttgaaa aaggtctggc
    17161 actagcagat atcaagcctt ctattcgtgg tgaggccttg tcgattcaag attttggcaa
    17221 attagctgat gctttaaaag aagttggatt ataaaagctt tcccccggtg acaataaaaa
    17281 aattcccttg tagacaaaac agagatgttc agttcagggg gatttttctt attgaagctg
    17341 gccgttaagg catcgtagtg cagagctagt ttttttaata cctcggaaaa aaaggggcaa
    17401 ttaacaagag cgtgactata gcggtacggt tagactcttt ttcgtaaata gcaaaggtct
    17461 tcttaaaatt catatcgttt cctacctcaa aaaatcatca gtgatctgat ttttagttga
    17521 taaaatattc tatttttaaa aagtagtgac ctaaatgata gccagtggtc tagagaatct
    17581 tgacagtttt ttaaggcgag tgaaacttag actcaaatgc tgatttggga gcggttttct
    17641 gatataatag agttattata gtagggcaaa ggagcacagt tgcaaggtaa aatcattaaa
    17701 tctctggctg gtttttatta cgtggagtca gaaggacagg tatatcagac gcgagcgcgt
    17761 ggtaatttta ggaagcgcgg tgagacacct tatgttggag atatcgtgga tttctcagca
    17821 gaggacaact ctgaaggtta tattttagcg attcatcctc gtaaaaacag tttggtaaga
    17881 cctcctatcg tcaatattga ccaagcagtg gttattatgt ctgctaaaga accagaattt
    17941 aacagcaatc ttctagaccg ctttctcatc ttgcttgaac acaaagccat tcatccagtg
    18001 gtttatatct ctaagatgga cttattagat agtcccgagg agattaaggc tattggtcga
    18061 cagtatcagg caatcggtta cgattttgtg accagtcttg aggaattgtt gcctttgcta
    18121 gctgataaaa ttaccgtctt tatgggacaa acaggtgttg ggaaatcaac ccttctcaac
    18181 cgaatcgccc ccgaattggc tcttgaaaca ggagaaatct cagatagtct agggcgtggt
    18241 cgtcacacca cccgagctgt gagtttttac aatacccatg gcggaaaaat cgcggatacg
    18301 ccaggtttct catcattaga ctatgatatt gctaatgctg aagatttgaa cgaggctttt
    18361 ccagagctgc gccggctgag ccatgagtgt aagtttagat cctgtaccca tacccacgaa
    18421 cccaagtgtg ctgtcaaggc agcgcttgaa acgggagagt tgtggccagt tcgttatgag
    18481 cattacctgc aatttctcag tgaaattgaa aaccgtcgtg aaacatataa aaaagttatc
    18541 aaaagaaagt aggtctactc catgtcaact ctaaaaattg ccccatctat tctagcagct
    18601 gattacgcta attttgcttc tgagctagct cgtattgaag aaacagatgc cgaatacgtt
    18661 cacattgaca ttatggatgg tcaatttgtt cctaacatca gttttggtgc agatgttgtg
    18721 gcaagtatga gaaagcacag taaattggtt tttgattgtc atttaatggt ggttgatcct
    18781 gaacgctatg ttgaggcttt tgcacaagct ggtgctgata tcatgaccat tcacacagaa
    18841 agtactcgtc atattcatgg agcccttcaa aaaatcaagg cagctggcat gaaagcaggg
    18901 gtagtgatta atccaggaac tcctgcaaca gccctagaac ctttgctaga cttagttgac
    18961 caagtcctca ttatgacagt caatccaggt tttgggggtc aggcctttat cccagaatgt
    19021 ttagaaaaag tggctaccgt agccaaatgg cgagatgaaa aaggattgtc ctttgacatt
    19081 gaggttgatg gcggagtaga caataagacc attcgtgctt gttatgaagc aggggccaat
    19141 gtctttgtgg caggttctta ccttttcaag gccagtgacc tagtgagcca agtccaaacc
    19201 ttaaggacgg ccttgaatgt ctaaagttgc tctttttgcg ggaggagatc tctcttatat
    19261 cagccgtgat tttgattatt ttgtcggtat tgatagaggg agcctatttt tattagaaaa
    19321 tgggcttcct ttgaatatgg ctgttggtga ttttgattcg gttccccaaa aagcgtttac
    19381 ggatataaaa gagaaggcag agctttttat tactgctcat ccagaaaaaa atgatacgga
    19441 tacggaatta gcccttaaag aggtctttgc tcgttttcct gaggcggaag tgaccatttt
    19501 tggggctttt gggggtcgaa tggaccatct cttatccaat atttttttgc ctagcgaccc
    19561 tggtattgct ccctttatgg cacaaatcgc cttgcgtgac caacaaaata tgctgaccta
    19621 ccgcccggca ggtcagcacc ttatccatca agaagaaggg atgacctatg tggcatttat
    19681 ggcagaagga gaagctgact tgaccattac tggtgctaaa tttgagttga cgcaagataa
    19741 ttttttcaaa aagaaaatct attccagtaa tgcctttatc catcaaccta ttacagttag
    19801 tttgccaagt ggctacttga ttattattca aagtaaagat tggagttagt atggacctta
    19861 tcttgttcct tttggtcttg gttctcttag gtttaggggc ttatctgttg ttcaaagtca
    19921 acggccttca acatcagctt gcccaaaccc tagaaggcaa cgcggataat ttgtctgacc
    19981 aaatgaccta ccagttggat acagctaaca agcaacaatt gttagagcta acacagctga
    20041 tgaaccgaca acaagcagac ctttaccaac aattaacaga tattcgtgac gtcttgcacc
    20101 gtagtttgtc tgatagtaga gaccggtctg acaaacgctt agaagaaatt aaccagcagg
    20161 tcaaccaatc gctcaaaaat atgcaagaat ctaacgaaaa acgtttggag gaaatgcgcc
    20221 agatcgttga agaaaaattg gaggaaacct taaaaaatcg tctgaacgcc tctttcgatt
    20281 ctgtatccaa gcaactagaa agtgtcaata aaggcttggg agaaatgcgt agcgtggctc
    20341 aagatgtggg tactttaaat aaggttttgt ccaataccaa aacacgaggc attttaggcg
    20401 aacttcaact aggccaaatc attgaggata tcatgacatc aagccagtac gaaagagaat
    20461 ttgtaacggt tagtggttct agtgaacgcg tagaatatgc gattaagctc ccaggaaatg
    20521 gtcaaggcgg ctatatttac ctaccgattg actcaaaatt ccctcttgaa gattattacc
    20581 gattagaaga tgcttacgaa gttggtgata aactggccat cgaggctagc cgaaaagcac
    20641 ttctggcagc tatcaaacgc tttgccaaag acattcataa aaagtacttg aaccccccag
    20701 agacgaccaa tttcggagtt atgttcttac caacagaagg tctttattca gaagtggtca
    20761 gaaatgcggc tttctttgat agccttcgtc gggaagaaaa tattgtggtt gcaggtcctt
    20821 cgaccctgtc tgctttgctc aattccttat ctgttggttt caagaccctt aatatccaaa
    20881 aaaatgctga tgacatcagt aaaattttgg gcaatgtcaa gttagaattc gataaatttg
    20941 gcggcctgct tgccaaggct caaaagcaaa tgaatacagc taataatacg ctggatcagc
    21001 tcatttcaac aaggacaaat gccattgttc gagccttgaa taccgttgaa acttatcaag
    21061 accaagcaac aaaatctctc ttgaacatgc ccttattaga agaggaaaat aatgaaaatt
    21121 aatcaaatga aaaaagacca gctttttgaa gggttctacc tcattaagtc ggcagaggtt
    21181 cgtaagacaa gggctggtaa agattttatt agccttacct ttcaggatga cactggcgag
    21241 atttcaggaa atctgtggga tgcccaacct tataacgttg aagaatttac cgctggtaaa
    21301 gtcgtgttta tgaaagggcg acgcgaggtc tataatggta cccctcaggt taatcaaatc
    21361 accttgcgaa atgttcgccc aggggagccc aatgatccaa aggacttcaa agaaaaggca
    21421 cctgtcagtg ttgaagaagt acgtgactat ttggaacaga tgctctttaa aattgaaaat
    21481 gcaacgtggc aacgaattgt aagggctctt tatcgtaagt atgataaaga attttatact
    21541 tatcctgcag ctaaaacaaa ccaccatgct tttgagtcag gcctcgccta ccatactgct
    21601 acgatggtca gactagcaga tagcattgga gatatctacc ctgacttaaa taagagtcta
    21661 ctgtttgcag gtattatgtt acatgactta gctaaagtca tagaattaac aggaccagat
    21721 aatacagaat acaccgttcg tggtaacttg attgggcata tttctctcat taacgaagaa
    21781 attacaaaag taatttcaga actacaaatc gatgatacca aagaagaagt cattgtcctt
    21841 aggcacgtga ttttaagcca tcacgggcaa ttagaatacg gtagtccggt acgtccacgc
    21901 atcatggaag ctgaaattat tcatatgatt gacaatattg atgctaatat gatgatgatg
    21961 acaacagctc ttagccgtgt tagcgagggc gagatgacca atcgtatttt tgccatggat
    22021 aatcggtctt tttacaagcc aaactattga tcagtgtttc tcaagtaata gttactttgc
    22081 ttttgtgatg atttttgatg tgcttaacac ttatgatggt ttcataagtg tttttggctc
    22141 ttgttgtggt tattaagtag aatgtccttt cagtaggaat gttgattagt ttatcttaga
    22201 ttgaattctt gcatgatatt aataagaaca aaaaaccaat attttcctaa tcgaatgttc
    22261 gttttttatt aactttatgg tataatagca aaaagtacat aaaaatgggg aaactatgaa
    22321 attaagacga agtgaacgta tggttgtcat ttcaaattat ttgattaaca atccgtataa
    22381 attaactagt ttaaacacct ttgcaactaa atatgaggcc gcaaaatctt ctatctcaga
    22441 agatatcgct attatcaaga aagcttttga agaagccaac attggtgata tcgatacact
    22501 tacaggagca agtggaggcg taatttttac ccccagtatt tcagaaacag aagcgcgtac
    22561 catcgttgaa gacctgtgtc aaaggttatc agagagtgat cgcatcttac ctggaggcta
    22621 tatctatttg tcagacttgc tgagtacacc taaaatttta caaaatattg gtcgtattat
    22681 tgccaatgcc tttaaaggag aaaagattga cgctgtgatg acagttgcaa ccaaaggagt
    22741 tcctttagca aatgcagtgg ctaatatttt aagtgttcct tttgtcattg ttagacgtga
    22801 tttaaaaata acagaaggat cgacagtgtc tgtcaattat gcgagtgctt ctagtgatcg
    22861 tattgaaaag atgtttctgt caaagcgtag tttgaaaccc aatagtcgtg tattgattgt
    22921 agatgatttc ttgaagggcg gggggacgat tacaggaatg atcagtctct tgacagaatt
    22981 tgacagcact ttagttggtg ttgctgtgtt tgcagaaaac gctcaatcag agcgtgagca
    23041 aatgaccttc aaatcattgc tgaaagtttc agagattgat gtcaaaaaca acaatgttgt
    23101 tgtagaagtt ggtaatattt tcgataaatg gaaaaaggag agagaatgga cttagaacaa
    23161 acgaagccaa accaagttaa gcagaaaatt gctttaacct caacaattgc tttattgagt
    23221 gccagtgtag gcgtatctca ccaagtcaaa gcagatgata gagcctcagg agaaacgaag
    23281 gcgagtaata ctcacgacga tagtttacca aaaccagaaa caattcaaga ggcaaaggca
    23341 actattgatg cagttgaaaa aactctcagt caacaaaaag cagaactgac agagcttgct
    23401 accgctctga caaaaactac tgctgaaatc aacaacttaa aagagcagca agataatgaa
    23461 caaaaagctt taacctctgc acaagaaatt tacactaata ctcttgcaag tagtgaggag
    23521 acgctattag cccaaggagc cgaacatcaa agagagttaa cagctactga aacagagctt
    23581 cataatgctc aagcagatca acattcaaaa gagactgcat tgtcagaaca aaaagctagc
    23641 atttcagcag aaactactcg agctcaagat ttagtggaac aagtcaaaac gtctgaacaa
    23701 aatattgcta agctcaatgc tatgattagc aatcctgatg ctatcactaa agcagctcaa
    23761 acggctaatg ataatacaaa agcattaagc tcagaattgg agaaggctaa agctgactta
    23821 gaaaatcaaa aagctaaagt taaaaagcaa ttgactgaag agttggcagc tcagaaagct
    23881 gctctagcag aaaaagaggc agaacttagt cgtcttaaat cctcagctcc gtctactcaa
    23941 gatagcattg tgggtaataa taccatgaaa gcaccgcaag gctatcctct tgaagaactt
    24001 aaaaaattag aagctagtgg ttatattgga tcagctagtt acaataatta ttacaaagag
    24061 catgcagatc aaattattgc caaagctagt ccaggtaatc aattaaatca ataccaagat
    24121 attccagcag atcgtaatcg ctttgttgat cccgataatt tgacaccaga agtgcaaaat
    24181 gagctagcgc agtttgcagc tcacatgatt aatagtgtaa gaagacaatt aggtctacca
    24241 ccagttactg ttacagcagg atcacaagaa tttgcaagat tacttagtac cagctataag
    24301 aaaactcatg gtaatacaag accatcattt gtctacggac agccaggggt atcagggcat
    24361 tatggtgttg ggcctcatga taaaactatt attgaagact ctgccggagc gtcagggctc
    24421 attcgaaatg atgataacat gtacgagaat atcggtgctt ttaacgatgt gcatactgtg
    24481 aatggtatta aacgtggtat ttatgacagt atcaagtata tgctctttac agatcattta
    24541 cacggaaata catacggcca tgctattaac tttttacgtg tagataaacg taaccctaat
    24601 gcgcctgttt accttggatt ttcaaccagc aatgtaggat ctttgaatga acactttgta
    24661 atgtttccag agtctaacat tgctaaccat caacgcttta ataagacccc tataaaagcc
    24721 gttggaagta caaaagatta tgcccaaaga gtaggcactg tatctgatac tattgcagcg
    24781 atcaaaggaa aagtaagctc attagaaaat cgtttgtcgg ctattcatca agaagctgat
    24841 attatggcag cccaagctaa agtaagtcaa cttcaaggta aattagcaag cacacttaag
    24901 cagtcagaca gcttaaacct ccaagtgaga caattaaatg atactaaagg ttctttgaga
    24961 acagaattac tagcagctaa agcaaaacaa gcacaactcg aagctactcg tgatcaatca
    25021 ttggctaagc tagcatcgtt gaaagccgca ctgcaccaga cagaagcctt agcagagcaa
    25081 gccgcagcca gagtgacagc actggtggct aaaaaagctc atttgcaata cttaagggac
    25141 tttaaattga atcctaaccg ccttcaagtg atacgtgagc gcattgataa tactaagcaa
    25201 gatttggcta aaactacctc atctttgtta aatgcacaag aagctttagc agccttacaa
    25261 gctaaacaaa gcagtctaga agctactatt gctaccacag aacaccagtt gactttgctt
    25321 aaaaccttag ctaatgaaaa ggaatatcgc cacttagacg aagatatagc tactgtgcct
    25381 gatttgcaag tagctccatc tcttacgggc gtaaaaccgc tatcatatag taaggtagag
    25441 actactccgc ttgttcaaga aatggttaaa gaaacgaaac aactattaga agcttcagca
    25501 agattagctg ctgaaaatac aagtcttgta gcagaagcgc ttgttggcca aacctctgaa
    25561 atggtagcaa gtaatgccat tgtgtctaaa atcacatctt cgattactca gccctcatct
    25621 aagacatctt atggctcagg atcttctaca acgagcaatc tcatttctga tgttgatgaa
    25681 agtactcaaa gagctcttaa agcaggagtc gtcatgttgg cagctgtcgg cctcacagga
    25741 tttaggttcc gtaaggaatc taggtgatgc attcgtcata agcaattgca tcaaaggaaa
    25801 aattctattt gacatgaagt gccgtctgtg ttactatatt agacggtact ttttactttt
    25861 ggtctctcaa aagtgtacag agacgtgctg acaattgttg caaaaagtgc accggatatg
    25921 ggctgtcacc aagtgctata tcaaccaaaa ataaaaaaac acaggagaat gtagatgcct
    25981 acaattaacc agttggtacg taaaccacgt aaatctaaaa ttgaaaaatc agattcacca
    26041 gctttgaaca ttggttacaa cagtcacaaa aaagttcaaa ctaaaatggc tgccccacaa
    26101 aaacgtggcg ttgctactcg tgttggaaca atgacaccta aaaaacctaa ctcagccctt
    26161 cgtaaattcg ctcgtgtacg tttgagcaac cttattgaag ttacagctta catcccaggt
    26221 atcggacaca acttgcaaga gcacagtgtt gttcttattc gtggcggacg tgtaaaagac
    26281 cttccagggg tacgttacca tatcgttcgt ggcgcacttg atactgcagg tgttgctgac
    26341 cgtaaacaag gccgttctaa atacggtgcg aaacgtccaa aaggataata gaagggggat
    26401 aagagaaaat gagtcgtaaa aatcaagcgc ctaaacgcga agtattacca gatccattat
    26461 ataactcaaa aatcgtaaca cgtcttatca accgtgttat gcttgacggt aaacgtggta
    26521 cagctgctac tatcgtttac gatgctttca gcgctatcaa agaagcaaca ggaaatgacg
    26581 ctcttgaagt atttgaaaca gctatggaca acatcatgcc tgtacttgaa gtacgcgcac
    26641 gccgtgtcgg tggttctaac taccaagtcc cagttgaagt tcgtccagaa cgtcgtacaa
    26701 cacttggact tcgttggttg gtaaacgcat cacgagctcg tggtgaacac actatgaaag
    26761 atcgtcttgc taaagaaatc atggatgctg caaacaacac aggtgcatca gttaagaaac
    26821 gtgaagacac tcacaaaatg gctgaagcta accgtgcctt tgctcacttc cgttggtaat
    26881 ataagatatt ttagcgtcaa acaaatgcta gccaaaatag ggaaattgac gcagaaactt
    26941 cagtttctag gtaattttat ctttgtggca gacatttgta gctaaaattc aactaatata
    27001 agatgtgaga gtgttaagca agtccaagac aaaataggaa tagtgacgca gaaacttcag
    27061 tttctaggaa ctattatctt tttgtcagtg gcttgtagct cgaactcaat taataagata
    27121 cgaaggcgta tagaacgcaa agtgaaaata ggaaatttga cgaagaaacc tttgtctcta
    27181 ggaaagttta tctttttcac acagcgttta gcctgagttc aatgaataag ataccaagcc
    27241 ttataaaggc aataggtatt atctttacca acaaatattt agataacggg taggtcctgc
    27301 ctatccgttt ttgctaaata gtgctataat gaaagagtaa actaaaaaaa taggagaaac
    27361 acatggctcg cgaattttca cttgcaaaaa ctcgtaatat cggtatcatg gctcacgtcg
    27421 atgctggtaa aacaactaca acagagcgta tcctttacta cactggtaaa attcataaaa
    27481 tcggtgaaac acacgaaggc gcatcacaaa tggactggat ggagcaagag caagaacgtg
    27541 gtatcactat tacttctgcc gctacaacag ctcaatggga tggtcaccgc gttaacatca
    27601 tcgacacacc aggacacgtg gacttcacca tcgaagtaca acgttctctc cgtgttcttg
    27661 atggtgctgt aaccgttctt gactcacaat caggtgttga gcctcaaact gaaacagttt
    27721 ggcgtcaagc aactgaatac ggtgttccac gtatcgtttt cgccaacaaa atggataaaa
    27781 tcggtgctga cttcctttac tcagtacaaa cccttcatga ccgtcttcaa gcaaatgcac
    27841 acccaatcca attgccaatc ggtgcagaag atgatttccg tggtatcatt gacttgatca
    27901 agatgaaagc agaaatctat accaacgacc ttggtacaga tatccttgaa gaagatattc
    27961 cagaagaata cttagaacaa gctcaagaat accgtgaaaa attaatcgaa gcagttgctg
    28021 aaactgatga agacttgatg atgaaatacc ttgaaggtga agaaatcact aacgacgaat
    28081 tgattgctgg tatccgtaaa gcaacaatca acgttgaatt cttcccagta ctttgtggtt
    28141 ctgccttcaa aaacaaaggt gttcaattga tgcttgatgc ggttatcgca taccttccaa
    28201 gcccacttga catccctgca atcaaaggtg ttaacccgga tacagatgct gaagaagaac
    28261 gtccagcatc tgatgaagag ccatttgcag ctcttgcctt caagatcatg actgacccat
    28321 tcgtaggtcg tttgacattc ttccgtgttt actcaggtgt tcttaatagc ggttcttacg
    28381 ttatgaacac atcaaaaggt aaacgtgagc gtatcggacg tatccttcaa atgcacgcaa
    28441 acagccgtca agaaattgaa acagtttacg ctggtgacat cgctgccgct gttggtttga
    28501 aagacacaac aactggtgac tcattgactg atgaaaaagc aaaagttatt cttgagtcaa
    28561 tcgaagttcc agaaccagtt atccagttga tggttgagcc aaaatctaaa gcagaccaag
    28621 acaagatggg tgttgccctt caaaaacttg ctgaagaaga tccaacattc cgcgttgaaa
    28681 caaacgttga aactggtgaa acagttatcg ctggtatggg tgaacttcac cttgatgtcc
    28741 ttgttgaccg tatgaaacgt gagttcaaag ttgaagctaa cgttggtgct cctcaagtat
    28801 cttaccgtga aacattccgt gcttctacac aagctcgtgg attcttcaaa cgccaatctg
    28861 gtggtaaagg tcaattcggt gatgtttgga ttgaatttac accaaatgaa gaaggtaaag
    28921 gtttcgaatt cgaaaatgct atcgttggtg gtgtagttcc tcgtgaattt atcccagctg
    28981 ttgaaaaagg gttgatcgaa tctatggcaa acggtgttct tgcaggttac ccaatggttg
    29041 atgttaaagc taagctttac gatggttcat accacgatgt cgactcatct gaaactgcct
    29101 tcaagatcgc agcatcactt gcacttaaag aagcagctaa atctgcacaa ccagctatcc
    29161 ttgagccgat gatgcttgta acgattacag ctccagaaga taaccttgga gacgttatgg
    29221 gacacgtgac agctcgtcgt ggacgtgttg atggtatgga agcacatggt aacagccaaa
    29281 tcgttcgtgc ttatgtacca cttgctgaaa tgttcggtta tgcaacagtt cttcgttctg
    29341 caactcaagg acgtggtacg ttcatgatgg tatttgacca ctatgaagat gttcctaagt
    29401 cagttcaaga agaaatcatt aagaaaaaca aaggtgaata accaccacta agaggttgag
    29461 gataactatc ctaacctctt ttttagtgta acagaacgtt atagtacagt ttgaagtttt
    29521 ggaaatcttt cccaataaaa agataaatta cagaatagaa aaagaaagcc ctttcctata
    29581 tttggtgggt tttgaaggct agaagaaaga agctgccctt tatgaaaatg gctaatttat
    29641 ttgcattttt tctgaaatag ttatataata gttctgttga aaggttgttg cagatgactg
    29701 taagttaatc ttttcacaat aggtagggag cattccctct aaataatatt cttttgattt
    29761 tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc ggtcgtatcg
    29821 gacgtcttgc attccgccgt attcaaaaca tcgaaggtgt tgaagtaact cgtatcaatg
    29881 accttacaga tccaaatatg cttgcacact tgttgaaata cgatacaact caaggtcgtt
    29941 ttgatggaac agttgaagtt aaagaaggtg gatttgaagt aaacggaaac ttcatcaaag
    30001 tttctgctga acgtgatcca gaaaacatcg actgggcaac tgatggggtt gaaatcgttc
    30061 ttgaagcaac tggtttcttt gctaaaaaag aagcagctga aaaacactta catgctaacg
    30121 gtgctaaaaa agttgttatc acagctcctg gtggaaacga tgttaaaaca gttgttttca
    30181 acactaacca cgacattctt gacggtactg aaacagttat ctcaggtgct tcatgtacta
    30241 caaactgttt agctcctatg gctaaagctc ttcacgatgc attcggtatt caaaaaggtc
    30301 ttatgactac aatccacgct tacactggtg accaaatgat ccttgacgga ccacaccgtg
    30361 gtggtgacct tcgtcgtgca cgcgctggtg ctgcaaacat cgttcctaac tcaactggtg
    30421 ctgctaaagc tatcggtctt gttatcccag aacttaacgg taaacttgac ggtgctgcac
    30481 aacgtgttcc tgttccaact ggatcagtaa ctgagttggt tgtaactctt gacaaaaacg
    30541 tttctgttga cgaaatcaac tctgctatga aagctgcttc aaacgatagc ttcggttaca
    30601 ctgaagatcc aatcgtttct tcagatatcg taggcgtatc atacggttca ttgtttgacg
    30661 caactcaaac taaagtaatg gaagttgacg gatcacaatt ggttaaagtt gtatcatggt
    30721 atgacaacga aatgtcttac actgctcaac ttgtacgtac tcttgagtac ttcgcaaaaa
    30781 ttgctaaata attagttata acgaaagaga gcttggttta tgctgagttc tttttcgtat
    30841 actttaaaca ctaccttaaa tgtatgattt taacgttttg aactattcta gactctagca
    30901 taaaagatat tttaaaatag ttcccttaat aaactgtata caaaaaggct aagatggaag
    30961 gggtgtctta gccttttttt gtctgactta aatttggaga gataaaaagt aaaatcttat
    31021 tttttaccgt aacgtttgta ctcgtgaata atcttcagag cacgttttct ggttttaata
    31081 ttgggacttt tcagtcttct gtaagctgac gataagtcag ttttttctgc cata
//
LOCUS       DAUGOH010000019        28646 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUGOH010000019 DAUGOH010000000
VERSION     DAUGOH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28646
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.019"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..155
                     /locus_tag="VH957_000970"
     CDS             <1..155
                     /locus_tag="VH957_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558889.1"
                     /translation="SLFMIATAAVAGLSLATLGSHQTVSANDASYSNGFYGHTGPDSW
                     LLYTVW"
     gene            565..801
                     /locus_tag="VH957_000971"
     CDS             565..801
                     /locus_tag="VH957_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558890.1"
                     /translation="MKKKLSLFMIATAAVVSLSLATPENQTVSANDTQVTCVGCPDCG
                     PKWSCCPLTCMRDLLRGWGKSAAYYCTWGYYYSE"
     gene            complement(987..1418)
                     /locus_tag="VH957_000972"
     CDS             complement(987..1418)
                     /locus_tag="VH957_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558891.1"
                     /translation="MKQQSYQPLRFVYLLVALFAAMLLIARPVMADGENNDPANAAYY
                     KGKSAGEEAGKTAGKEASWTDLTPTNPTIPEPPSDIRETTNKQHYKDGYTDGYRDGYN
                     EGWKSQHPVLTPVKVIWDLISHWLQQFFPNNQATTTVQSMS"
     gene            complement(1673..3388)
                     /gene="slo"
                     /locus_tag="VH957_000973"
     CDS             complement(1673..3388)
                     /gene="slo"
                     /locus_tag="VH957_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEQ8558892.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRS
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(3412..3897)
                     /locus_tag="VH957_000974"
     CDS             complement(3412..3897)
                     /locus_tag="VH957_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEQ8558893.1"
                     /translation="MYKVPKSLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMVHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(3902..5257)
                     /gene="nga"
                     /locus_tag="VH957_000975"
     CDS             complement(3902..5257)
                     /gene="nga"
                     /locus_tag="VH957_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEQ8558894.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFVSPM
                     RIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            complement(5628..6167)
                     /gene="nusG"
                     /locus_tag="VH957_000976"
     CDS             complement(5628..6167)
                     /gene="nusG"
                     /locus_tag="VH957_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEQ8558895.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(6340..7383)
                     /locus_tag="VH957_000977"
     CDS             complement(6340..7383)
                     /locus_tag="VH957_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8558896.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIETAK
                     KAIIEGTITVPEN"
     gene            complement(7710..9002)
                     /locus_tag="VH957_000978"
     CDS             complement(7710..9002)
                     /locus_tag="VH957_000978"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEQ8558897.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGERIDHYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            9440..10318
                     /locus_tag="VH957_000979"
     CDS             9440..10318
                     /locus_tag="VH957_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558898.1"
                     /translation="MIKKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLVKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPQIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHDANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            10331..11593
                     /locus_tag="VH957_000980"
     CDS             10331..11593
                     /locus_tag="VH957_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEQ8558899.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQSPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTHA"
     gene            complement(11713..12339)
                     /locus_tag="VH957_000981"
     CDS             complement(11713..12339)
                     /locus_tag="VH957_000981"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEQ8558900.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYAIIPQLEETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(12384..13799)
                     /locus_tag="VH957_000982"
     CDS             complement(12384..13799)
                     /locus_tag="VH957_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEQ8558901.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(13800..15575)
                     /locus_tag="VH957_000983"
     CDS             complement(13800..15575)
                     /locus_tag="VH957_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEQ8558902.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     ESNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            complement(15776..16096)
                     /locus_tag="VH957_000984"
     CDS             complement(15776..16096)
                     /locus_tag="VH957_000984"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEQ8558903.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(16093..17091)
                     /locus_tag="VH957_000985"
     CDS             complement(16093..17091)
                     /locus_tag="VH957_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEQ8558904.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            complement(17107..17691)
                     /locus_tag="VH957_000986"
     CDS             complement(17107..17691)
                     /locus_tag="VH957_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEQ8558905.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(17760..18239)
                     /locus_tag="VH957_000987"
     CDS             complement(17760..18239)
                     /locus_tag="VH957_000987"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEQ8558906.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(18241..20241)
                     /locus_tag="VH957_000988"
     CDS             complement(18241..20241)
                     /locus_tag="VH957_000988"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEQ8558907.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKQHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(20231..20551)
                     /locus_tag="VH957_000989"
     CDS             complement(20231..20551)
                     /locus_tag="VH957_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558908.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(21005..22024)
                     /locus_tag="VH957_000990"
     CDS             complement(21005..22024)
                     /locus_tag="VH957_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEQ8558909.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(22061..22426)
                     /locus_tag="VH957_000991"
     CDS             complement(22061..22426)
                     /locus_tag="VH957_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8558910.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            22600..23280
                     /locus_tag="VH957_000992"
     CDS             22600..23280
                     /locus_tag="VH957_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8558911.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVAKDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(23402..24049)
                     /locus_tag="VH957_000993"
     CDS             complement(23402..24049)
                     /locus_tag="VH957_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8558912.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(24052..24711)
                     /locus_tag="VH957_000994"
     CDS             complement(24052..24711)
                     /locus_tag="VH957_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8558913.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(24723..25907)
                     /locus_tag="VH957_000995"
     CDS             complement(24723..25907)
                     /locus_tag="VH957_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8558914.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLIDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            26028..26939
                     /locus_tag="VH957_000996"
     CDS             26028..26939
                     /locus_tag="VH957_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8558915.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEVKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKTSHLKHYIKHTILDYFMNQRF"
     gene            complement(27008..28414)
                     /locus_tag="VH957_000997"
     CDS             complement(27008..28414)
                     /locus_tag="VH957_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEQ8558916.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSLVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFLVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
BASE COUNT         8679 a         6107 c         5019 g         8841 t
ORIGIN      
        1 tatctttatt tatgatcgca actgctgctg ttgcaggcct tagccttgca acactaggaa
       61 gccaccaaac tgtttcagca aatgatgcta gctatagtaa cggtttctac ggacacactg
      121 gtcctgacag ctggttactt tacacagtat ggtaaaccta ataccgtaac atagaagcta
      181 tcttcttcgt aagactacgg ttatgaaaag cctagagctg cgtaagcagt tctaggcttt
      241 ttgattggct aaaacgtttt tactaacgat ccctcaagat taaaaagaaa aggcataccg
      301 cctataaaag gacaagccca aaacacaagt cgtaacagtt gctagctaac caccaccaaa
      361 aaagctgtaa cacctcaaat ataattataa ccagattaac attattaata attaatgtta
      421 tttatataag ataaagaaat gctttagtat cggctttctt tgcctttttc ggtcaaacac
      481 ataacaaaaa gattaaaatg tgatattgaa tcattaacat aatatgagta taatataggt
      541 atactataat ttaaggagtt acaaatgaaa aagaaattat ctttatttat gatcgcaact
      601 gctgctgtcg taagccttag ccttgcaaca ccagaaaacc aaactgtttc agcaaatgac
      661 acgcaagtta cttgtgtagg atgtccagat tgtggtccaa aatggtcttg ttgtccattg
      721 acctgtatgc gcgatttgtt aagaggttgg ggcaagtcag cagcatatta ttgcacttgg
      781 ggatattact actctgagta aaaattactt gagagtctga gacagtagtc tcttgattat
      841 gctaaaaaaa caatggcttt gacgccattg tttttttgtg tggccgagag gctttttcac
      901 aaactctttt tttattgttc attcccatat cctaaaaaaa caacctttca cattagcagt
      961 taaaggctgt ttttaattca tttttattat gacatgcttt gtactgttgt agttgcctgg
     1021 ttattgggga agaattgctg tagccaatga gagatcaaat cccatataac cttgaccgga
     1081 gtcaagacgg gatgctgaga tttccagcct tcattataac catctctgta cccatctgta
     1141 tacccgtctt tataatgctg tttattagta gtctctctga tatcactagg tggttctgga
     1201 atggttggat tagttggggt caaatcagtc caactagctt cttttccagc tgttttccct
     1261 gcttcttctc cagcgctttt ccctttataa tatgctgcat tagctgggtc attattctcc
     1321 ccatctgcca taacaggtct tgctataagc aacatagcag caaatagagc caccaagagg
     1381 tagacgaagc gtagaggctg gtaagattgt tgtttcatga taatagttat ctctcccttt
     1441 tatgttatgc tttgcttgtt aaaaagcagc ttgttagtat tatagattag aagcagctta
     1501 gcttcaaggt cacgatgtga gaaaagaata attttttgat tagtatatca aaaaagcttg
     1561 tctatgaagg tatctcatag acaagctttc ttctgtattt gtgagaggat taggcacaag
     1621 gcctcaagag ataagcagca tcaaggtgct tgacgaacct cttgaaccag tcctacttat
     1681 aagtaatcga accatatggg ctcaaggttg atcctgagat gttgacattg atttctttag
     1741 acagtttcac atctctttcg tcgatcactt ttcgccacca ttcccaagct aagccggtgc
     1801 actctctagc catgatacgg atatttcgtg aattagctcc tagtgggata actgtgctaa
     1861 atggtgatgt cttactatac cagttgttgt cccaacgtcg ttttgtaatc acttcttttc
     1921 ctttgtcatc ataattgatt tcatcccaaa ggatttcata ttgagcaaca taggcacctt
     1981 gatgagacag gttaattttt ccactcgtgt actcggtaga tgttgtttca acgtattcac
     2041 ttctgttatt gacacccgca attttattat ttttaaggaa aacactggtg tatgaaatag
     2101 gataagctgg gttttttcta ctgaaggtag cattatcttt gataacgttt ctaataacat
     2161 caaagtcttt tgtgactacc ttattgtgct ctgcagcatc tcctcctaaa acgacagctg
     2221 taaatgaact attttctaaa atatcagagt attttccatt agttttaaca tctgttcctt
     2281 ttagagctgc actaaaggcc gcttcaacat cattactttt agaacttgtt tctagtttga
     2341 caaaaacagt tcgaccataa gctacgttac tcacaaagag tggcggggct tcattgctga
     2401 caccttttcg ttgcaactct ttaaaggtca ctgatttatc aaacacatcc gcaggattat
     2461 taggaaggtt tgctgatacg gtgtaaaaaa tttgcttgta tgctgcaatc atcaccttct
     2521 tttcaccttt tgaaatcgac ttgaaatcaa tgcctaaagt accatctaag attttactat
     2581 taacatttag agctgcttca atctgtgatt tagaatatac cattgattca gtatattgtg
     2641 ttctggcagg aagcgtatta ccaccagaat aattatcatg ccattggtta acaagattat
     2701 caatagctgt tgaaacattg gcataggtag ggtcattgac ctcaaccgtt gctttgtctc
     2761 ccatacctgg taaatcaata tggatttttt gtgggtttcg cttggtgact accgcgtctg
     2821 gtttgttttc ggtaaaacct ttattagcca gctgaagggc tgctggatag gtcctatcag
     2881 tgacagagtc aatgatggaa atatcgactg gtgtagtgtt gatatttttt ttctttcttt
     2941 caatgacaat aaatttatca gctttcttaa cgccttcttt aggaacaaaa ttttcaatgg
     3001 tttcaccatt tttagcaagt acttcaagct cattataatt tagtgaataa atcttgtcat
     3061 tgatttcttc agtgtgatct tcttcgctct tttttttgtc ttctgacttt ttttcttctt
     3121 tttctgcaga ttctagtggc atttctttgg gagcaagctt aatcatatcg ttagagttaa
     3181 gcatatcatc cattttctga cctgcttttt cggtagttag ctcactactt tctggctttg
     3241 gttgctcatt tgtcgttgtg gtttctgtac tagcagtgtt ttgtttgttc gattcagcat
     3301 tagcagtaac aagattacca atgataagag ctgccgttag tagcccagcg acgcgactgt
     3361 attttttaaa tgtttttttg ttagacatgt ccttcatacc tttttatcat tctaaaatgt
     3421 ttctattgtt ctttcgacca tatcaagcat agtatcttga tagtgagcaa attctcctaa
     3481 tttgtaatgt accatagcct ctctaatatg cgcatctttt aacgctttgg ttatattagc
     3541 tagtatgctt tgacggttta aataaaatgg caagctttcg taataattta ataacatgtt
     3601 ttcagcgttt agggtttgaa ccgcttggta aatgtctaat gcttgaccgc tatttgacat
     3661 ttctaataat gcttcttcga tgttagcttt caattgggta tagcctttta tgaaagcagg
     3721 gtaaacccca tactctaaaa taacttctgg atcagaaata tctcccatat aggagtctct
     3781 tctagtgata cgatactctt tgtcactacc tatcaagtat ttttttaaat cattaacagt
     3841 tacttctttt tgaaacattt tttgataatg ttctaaactc tttggcacct tatacatatt
     3901 gttacttcct atcttgcatt ctatcttgca ttttcttaat tttgaagcga ccagttactt
     3961 ttttatggtc accatttgga gcaatgatgg taggatcaat aatttcaaaa tagcctttgg
     4021 catcaatctc tgctaagaca gctttagatt ttagatcttt aacactaatc gatgggaaaa
     4081 ttaactcact ttctgaattt tcaatgtgtt ttcctgacca cgtttggcaa ccaggaatgt
     4141 tgagcgaatt tgctccaggg gtatctccgc tagctgttcg gatatagcct agcttatcaa
     4201 tgttttttgt tagttcagaa tcgtactcat attgataaac tccatcgcta tattttccgc
     4261 tatcgacacc ttttatattt tcaatttggt cagctgattt taacttacct tgatcagtaa
     4321 agagcaatgc catatcttca gcaaaacttg tcacaaaaag accgttttct tgtcgaccaa
     4381 tcgttgactt tcttttagca tcatcaaaag ctaacatcaa atctttttta cttgtaacgt
     4441 gagaagctcc gctttctttg tagacttgtt ttagtttttc aacaaactct tttttgtagt
     4501 ggtatttgcg gctaacgtac atccggtaat actcagcacg tgacgcaaca gcagacatct
     4561 gaacagcttt atcagcatac ttgtcggcag tttcaataaa ctcatctgct tgtttatctg
     4621 ttacccattt atctttaatt tctttaaact ttttttcaaa aagatcgcgt tccatattgc
     4681 caaaagtgac ctctgacaag gctaaaatat ccttgttttg tccctgatgg acctctgtta
     4741 cctcaatatc aatacgatca acatctaatt ttttatcaat ctcaatgtga tgcggttttt
     4801 tagtgtaggt gtcgcctaat tcaatttttt gaaagaggac caatttattc ccgttatagt
     4861 atttaacatc agcctttgca attctatttt tcttgtagta attctccttg ctagatgtat
     4921 ctccattcac aattaaaatt ctcccaatac gcatcgggga aacaaacttg taggaaagta
     4981 cctcaccaac gccaccacca ggtgaatttt cctcccagac agtactcatt gagccgtcta
     5041 atgtgtgcat gacatgattg tcttctttag aggaagttgc gttagcttcc ataactttgg
     5101 tcgtttcata tttgacatcg ctttttttat tttctttgcc actaacagcg tacgttgtgc
     5161 tattagctaa taaactgcta cccattgctc cagccaaagc aatagcaaca cttgtctttg
     5221 cgacaatatg agctaatgtt acttttttgt ttctcatgta aaccacctta tattattttt
     5281 aagtaaacta tacattaaca actagttttt gtcaatgcga tttattaaca tcgttttagg
     5341 cttttctatc aaaaaaatga acacaaaaaa acaagtagcc aactgttaca agtttcaagg
     5401 ggatatttcc atcttattat cacagaacct tcacatctgt tctatttaaa ccagattaaa
     5461 agtactagtt aaatatttga tagtagcacc gttatcagta atagatctgt taattatttc
     5521 tgattacaat gatgttaaca atagtcatcc attggtttgt aaacacgctt cactgccaac
     5581 taaaaaaggt ctgatggtaa tacttatacc atcagacctt tgagagccta tagttctgca
     5641 atttgataaa gttcaacttc tgctactgtt tcagagccaa acatgttgag catcagcttc
     5701 actttgttgt tttcgatttc taccacacga ccttcttgtc ccataaaggc accgtctatg
     5761 atctgaacca catcaccttc tttgatattg gtatcaaaga catcaatggt ttgacccata
     5821 gacaacaaga tagcacggat ttcttcttca agaagtggtg ttggttttga tcggttcccg
     5881 tgtgatccca caaaacctgt aacgtttggt gtgttacgca caacaaacca agcttcatct
     5941 gtcatgacca tttcaaccaa gacataccct ggaaagcgat tttcttcgat ttctttggtt
     6001 tgcccatttt tttcaacgtt aaccgtttgt gtcggaattt cgacgcgcaa aatattgtcc
     6061 aacatgttat aggtttgggc acgttgcaag aggttttctt ttactttgtt ttcgtagcct
     6121 gagtaagttt ggaggacgaa ccagccctta tcaaatgaat ctagcatgat gtttcctttc
     6181 attataaaaa agcccttttt ttggcttttg cgctgttttc tatcaccttc attataataa
     6241 aagacagggc tggtgtcaac gtatctgtgg agctacttga cacctttatt aaaaagtcca
     6301 aagtcggttc gtgacgactc tggacggtat tgtacagttt tagttttcag gaactgtgat
     6361 ggttccttcg ataatcgctt ttttagcagt ctcaatagct tttttagtgt cttgtgtcag
     6421 agcatccgtt gtaaggctaa caccaccttc ttttaaacca aaagtggtta tttgaccacc
     6481 tgggaattgg ccttctgagg tttttacggc tacttttact aaagcttttc cgacttcctt
     6541 gatacttgag gtcaaaacaa aattagctga cttgccatct tttgtggtgt attttccatc
     6601 ttcactttgg tcacggtcaa caccaataac ccaaacctta tcttcttctt tacgtttttc
     6661 gttgatagac ttagcttcgc taaagacacc cgcccctgtg cctcctgctg catgataaat
     6721 aacatctgcg ccttcagcat attgagcagc tgcaatcgtc ttgcctttgg cagcatctgc
     6781 aaaagagcct gcataagcaa ctcttacttt gatggtatca tctactgatt tcacaccagc
     6841 ttcaaaacct ttttcaaagc gcttgacaac atctccttcc ataccaccta caaaaccaac
     6901 ttgcttggtt tttgtcgttt tagctgctgc aacaccggct aggtatgccg cttcatggtc
     6961 tgaaaaggtg atacttgcaa catttttttg acctttaatc acatcatcca caattgcaaa
     7021 atggttgtca ggattgtttg cggctacttt ttctacagcg tcatgtaatg gaaatccaat
     7081 cccaaaaaca agattataac cattggttac tgctgactca aggtttgtgg taaactctga
     7141 ttcattggct gattggaaat aatcatagcc ttttcctttt tcaagtttat tttcttttcc
     7201 ccaagcttgt aagccttccc aggctgactg gttaaatgac ttgtcatcaa tacccgtctg
     7261 attagtgatc atagcgattt ttaatgaatt gtcagttgtt tgtttagagg agttattggt
     7321 gcagcctcct aatgtgaata gggcagtcga aacaagacca agtgacatta cttttttgtt
     7381 catgtgaaaa tgaacctcct aaatgtttaa tcctaaagtg atgtgtcatt gttaacgttc
     7441 tacttatgct ctagaacgaa aagtttagta tatcaaaaaa atcagtttta tcctactatt
     7501 tttgctgaaa aatctctttt tcaccaaaat gaccgaacga gaaagtgaga tcaactggta
     7561 aaacccgtta tctcctcaaa aatcacctct taaggagata agacaacgac aaaactcaag
     7621 ctactagtaa tagcatgact aactacacaa tccaacaaac ggtaaaaaga gctggaaacg
     7681 ctatccaact ctttgtcata ctagacacct tagatagatg cccagaccga ctcaagaata
     7741 ttggtctgtt cacgtcctgg accaactgag aaggttgaaa tgcgaacgcc aaccaattct
     7801 ccaacacgac ggacatagtt gcgggcattt tcaggcagct catcaagact acgaacaccc
     7861 gtgatgtcct cttgccagcc tggtaattct tcatagattg gtttgcaacg tttgagttgt
     7921 tcaagacttg ctgggtagtg atcaatacgt tcaccatcta aatcgtaagc cacacaaatc
     7981 ttaaccgtat caagtcctga aagaacatca atggaattga gggaaaggtt agtaatccct
     8041 gacacacgac gactatggcg cataacaact gagtcaaacc aaccgacacg acgtggacgg
     8101 ccggtcgttg tcccgtactc atgacccact tcacgaatgc gctcacccac ttcatcaaag
     8161 agttctgtag ggaatggccc atcaccgaca cggcttgtgt aggctttaca gacaccaact
     8221 actttgttga ttttacttgg gccaacccca gaaccaatag tgacaccacc agcaactggg
     8281 ttagatgagg ttacaaatgg gtaagttcct tggtcaatat caagcataac cccttgtgca
     8341 ccctcaaaaa gaacacgttt cccagcatca agtgcatcat ttaaaattac agaagtatct
     8401 gtcacatatt gtttaatttc ttgaccataa gcatagtatt cttcaaaaat agcatcaaaa
     8461 tcaagaggtg tactgtcata cattttttca aataaacggt ttttctcagc taaattaatg
     8521 cgtaggcgct ctgcaaagat atccttatcc agtaaatctg cgatacggat accaactcga
     8581 gcagctttat ccatataagc tggaccaatc cctttaatag ttgttccgat tttattgtca
     8641 ccttttgcat cttcttgcag ttgatccagc tggatatgat aaggtaaaat gacatgagct
     8701 cggtctgaaa tgcgaaggtt atctgtcgtc actccttcat catgcaggta cgccaactct
     8761 ttgaccaaag atttggggtt gaccacaaca ccattaccaa taacggaaat tttttgcggg
     8821 aagaaaattc ctgatgggat caagtgaagt ttaaacttct taccatcaat cacgatcgta
     8881 tgaccagcat tatcaccacc ttgatagcga gcaattactt ctgcatccgc tgacaagaaa
     8941 tcagtgattt tacctttacc ttcgtcaccc cactgggtac caacaacaac tacagatgtc
     9001 atatcattgt cctaactttc tgaaacactt attctcaata aaaatcatag gcaagctaac
     9061 cactgcttaa aaaccaaaaa gaaggtcaga tctgtaagat cagcaatgta gctcttgata
     9121 tttaaagaaa acaggcagga atctcacctg ctagcatata tcttacaact tattatagca
     9181 aaaaatgatt ttttctgcta gatttcttag cattattaag gaaaaagaga aactcttttt
     9241 ttaaccatga taaacaatcc taaaaaaacg aacattataa gagaaaagct tttaacctcg
     9301 tttctcctaa actttagcag ggttaaacga ttctcttaaa acattagctc ttttctttca
     9361 gaaatagcgg ttttaaggta aaataatagt aagttacctc tatgagatag ccagtaaaaa
     9421 catatcgagg aaatatcaca tgattaaaaa gtatgaccgc acgagcacaa aaaagaaatc
     9481 actaaactgg atttggctaa tcatcgcttt ttttatgatt tcaagcttta taggtggctc
     9541 ttcttttact gagtcacttc tagacatttt gcctgccata gccattggtg gtacaggtta
     9601 tgctattttt cgtgttagat ctcatcaaaa gcggctagta aaggccaaga ttgccaaaca
     9661 attagaagat ctaaaagcaa aaattcagct agctgatcgt aaagttcggc tgttagacac
     9721 ttatctggca gaccatgatg acttccaata taacgtacta gctcagcaat tattaccaca
     9781 acttagtgac atcaaagcaa aagctattac gttaaaagac cagttagatc cccaaattta
     9841 tcgtcgtatc accaaaaaag ccaatgacgt tgaaagtgat attacccttc aactcgaaac
     9901 actgcagatt gccacaactc ttaaccctca gcctttgaaa accccatctc ctaatcttat
     9961 taacaaagca cctgagctca aaccgtatta tgataatatt cagacagatc atcaagctat
    10021 ccttgctaaa atccaaggag ccgacaatca agaagaattg cttgcgctgc atgatgctaa
    10081 catgaggagg tttgaggata tcttaacagg ctacttaaaa atcaaagaag agcctaaaaa
    10141 ttactataac gctgctgctc gtttagaaca agccaaacaa gctatccaac aatttgatga
    10201 agatcttgac gaaacccttc gtcgactcaa tgaaagtgat cttaaagatt ttgatattag
    10261 ccttcgaatc atgcaaggtg ctactcaaag acgaacaacg catcaccaaa aagactaaag
    10321 gagtcccttt atggcagatt ttaattttga tattgaccaa attgctgaca atgctgttgt
    10381 caaaaccgat aaaaccaccg atattatctc agacttacca actgacacaa atggccaaat
    10441 ctcttttttt gagaaactaa gtgctgacca gcagacagct attactgcca aagccccggc
    10501 attggtagat acctttttgg cagaccaaaa tgcgctactt gattttggtc agtctgctgt
    10561 tgaaggggtc aatgcaacgg ttaatcatat cttggcagag caaaaaaaat tacagattcc
    10621 tcaggttgat gatcttttaa aatcaaccaa tcgtgaactc aatggtttta tcgctaaata
    10681 caaggatgcc acacctgtgg accttgataa aaagccaaac tttcttcaaa aactctttaa
    10741 acaaagccgt gataccctgc aagagtttta ttttgattct caaaacattg agcaaaaaat
    10801 ggatagtatg gctgcagcgg ttgtcaagca agaagatacc ttagctcgca atattgtctc
    10861 agcagaattg ttaattgaag ataatactaa gtccattgaa catttggtag gcgtcattgc
    10921 ttttatcgaa gctagtcaaa aagaagctag tcagcgcgct gcggctttac aaaaagacct
    10981 aaaaaccaaa gacagtgcta caccagacta tcaaataaaa gctgatcttt tggcaagaac
    11041 taccgaagtc atcaacaccc tcgaacaaca acacaccgaa tacttgagtc gcctctatgt
    11101 tgcttgggcg acaactccgc aaatgcgtaa tctagtcaag gtctcttctg acatgcgtca
    11161 aaaactaggc atgttacgcc gcaataccat tccaacgatg aaactatcta ttgctcagtt
    11221 aggcatgatg caacaatcgg ttaaatctgg aatgactgct gatgccatta ttaatgctaa
    11281 taatgctgcc cttcagatgc tagcagaaac aagtaaagaa gccatcccag cattggaaca
    11341 atcagcacaa agccctactt tgtctatgaa atctgtgaca agtctggcag aaagtttagt
    11401 agcacaaaat aatggcatca ttgcggcgat tgatcatgga cgcaaagaac gagcacaact
    11461 agaaagtgct attatcaggt ctgccgaaac cattaacgat tctgtcaaac tacgtgacca
    11521 aaatattgtg caagcacttc ttagtgaagg caaggaaact caaaaaacaa ttgataaaac
    11581 aactcacgca taagctaaac atcacctgtc acgctactta aaaagcaagc catcagttag
    11641 gttaatccct ttgatggctt gcttttttac tacttaacga ataatcgcct tgtttgatat
    11701 aacacttatc ttttatgatg ttattttcat aatacgaaca aggctagcac gctcggcctc
    11761 ttctaatttc aactcaatgt agtgaatcgt ctcttccagt tgcgggataa tagcatactc
    11821 taagccattg acgcgacgtc tagtcttttc aatgtcatca gccattagtt gacaagtttt
    11881 ttcaacttca gctaaccgta agagcttttc taatagttct tttgtctttt ggatagtatt
    11941 gtccatctca ctatttgagc tgaggtaact ataagcaaac tcaccttgtt cttgctctct
    12001 tgccgtatta gactggacat ggaatttagg cacattgaca ctcatgatat tttcaatatc
    12061 aatccataag gtcacttcat ggactggaac agcaaagagt tcttctacca ttagactatt
    12121 ttcagatgct tttgccaaga caaactcctt catattggca gcaagttctt tttcgatagt
    12181 ttgacgaagc tcattgtttt cacgaattaa atcaacgaag cggcgcatca attcatctcg
    12241 cttgtccttt aataatttat gacctcttgt agctgtcttc aatcgatttt tcaagttact
    12301 aagttccatg cgtgttggtt taacatttaa tcgtgccatt gatataactc ctttcgtcaa
    12361 gggcttgaaa ttgcatggtc aactcaatca tttgcaacaa aaacctttgt catcgtggta
    12421 tctgctttag gcaaataacg atctaacata tcatctttaa tgcgttttaa ttcggtacgt
    12481 ggcaaaatcg acaacaattc ccaacccaag tcaagacttt cttcaatgct acggttggtg
    12541 taaaatcctt ggttaatgta ttcttcttca aaccggttgg taaaggccac atatagttta
    12601 tccgtttcag aaagggctga ttcaccgagc acaacagcca attccttagc ttgttttcct
    12661 tgggcatagg ctgcaaagag ctgattcatt gtggcagcat ggtcttgtcg agtcttacct
    12721 tcacctgagc ctttatcttt taggcgagat agcgatggca agacattaat aggcggtcta
    12781 aaaccatttt tatatagttc ttgcgacaaa ataatctgac cttcggtaat ataacctgtc
    12841 aaatcgggga tagggtgggt aatgtcatct tctggcatgg ttaaaatagg aatttgagtc
    12901 actgaccctt ttttcccgat caagcgacca gcccgttcat ataaggtgga gagattagta
    12961 tagagatagc caggataacc tcgtctgcct ggaacttctc tgcgagcggc tgatacttct
    13021 cgtaaggctt cacaataatt tgtcatatct gtcatgatga ctaaaacatg catacctttt
    13081 tcataagcca agtattcggc tgttgtcaga gctatacgtg gtgttgcaat gcgttcaata
    13141 gcagggtcat tagctaaatt gataaataaa acagatcgat caatggcacc cgtttcacgc
    13201 aagtcattca taaagaattc tgcctcttca aaagtaatac ccatagctgc aaacacaacc
    13261 gcaaagttat catcagagtt tagaacagtt gcctgacgag caatctgtgc ggccaattca
    13321 ttatgaggta accctgagcc cgaaaaaact ggtaactttt gaccacgaac gagggtattg
    13381 aggtgatcaa tagctgagat acctgtctgg ataaattcgt ctgggtaatc acgagcgaca
    13441 ggattgatcg cttgaccatc aatatcaagg tatttttcgg gaataagttc tggaccgccg
    13501 tctatgggct gccccattcc atcaaagatg cgccctacca tatcttctga tacggctaat
    13561 tccaaaggat gccctgtaaa tcgaaccttg gttttggcta ggttgatgcc agttgatcct
    13621 tcaaatagct gtaccatagc cttgtcacct tggacttcta agacttgacc tttacgcctt
    13681 tctccattat gcaaagtaat atctaccaat tcgttgtagt gcactcctgc aacttgatca
    13741 acaatcatca aagggccaac cacttcgcta accgtccgat attctttgag aacgctcatc
    13801 taaattcctc cctttgctaa aacgtggtga atctctttgg taaccttctg agtaagccct
    13861 ttaatctgct ctaagttttc ttctgggata aatttgctgc gtgcgatgcg atcgcgtacc
    13921 tgagcagtgc cttccataat ctcattaaaa taagctccca aagaaagggc tttgctggct
    13981 tcctcattaa aggtcaaaat attggttagc atggcctctt gtttcggaaa ggaagtaaag
    14041 gtatccaccg aatcaaaggc attttgctgg agataatcct cccgaatttg ccgggcaaca
    14101 gccatggtca aacgatcttg ttcagacagt gaatcaagcc ccaccaagcg tacaatttct
    14161 tctagactag cttcacgctg caaaatagcc atggcacgag ttaccttgtt ggaccaatta
    14221 gattcctgtt tacggtcaat atagcttcct acatcatctt gatacaatga ataagacgtc
    14281 agccagttaa tcgctgggaa gtgacgccgt tgcgcaagag gcgcgtcgag cccccagaaa
    14341 actttgacaa tccgaagggt gttttgagtg acaggctctg aaatatcccc tccaggagga
    14401 gaaaccgcgc cgatggctgt aatggttccc tcacgttctt gacttcccaa ggtccgaaca
    14461 cgaccagccc gttcataata ttcggcaata cgactcccta agtaagccgg gtagccttca
    14521 tcaccaggca tttcttgtag gcgtcctgac atctcgcgca gagcttctgc ccaacgtgat
    14581 gtcgagtctg ccatgatagc cacagaatag cccatatcac ggaaatattc ggcaatggta
    14641 atgcctgtgt aaatcgacgc ttcacgcgct gctactggca tattagaggt gtttgcaatt
    14701 aacaccgtgc gctccataat ggactggcct gtatttgggt caattaactc tggaaactca
    14761 ttcaaaacgt cggtcatctc gttgccgcgt tccccacaac cgacataaat aacaatatca
    14821 acattggcaa atttagctat ttgatgctgc acaactgttt ttcctgcccc aaatggtcca
    14881 ggaacagcag cggcaccacc ttttgtaaca gggaaaaagg tgtcaataac ccgttgacct
    14941 gtaaccaaag gttcgactgg gataagcttt tgagcaacag ggcgactttg acgaactggc
    15001 caagtctgca tgaggctacc ttggtaaatg gaaccgtctt cctgcttaat ttcataaact
    15061 gtatctgtta ctgtgaagtc acctgcatga atagccacca aggtccctga aactttataa
    15121 ggaaccatga tacgatgctc aatgacagct gtttcttgca cagttcctaa aatatcacct
    15181 gcaactactt cttgaccaac acttagcttg ggaataaatg cccacttagc ctttcgatca
    15241 agacttggga tagccacacc acggattaaa aagtcgctgt ccgttgcttt ttgaaaacga
    15301 tcaagcggtc gctgaatacc gtcaaacatt tctgaaatca ggcctgggcc taactcgacc
    15361 gacaaaggac aaccagtagt cactactggt tctcctggac cgatccctga tgtttcctca
    15421 taaacctgaa tagacgcttg atcgcggcgc atttcaataa tttctccgac taagccaaga
    15481 tgtcccacac gacaaatatc ttgaatatta gcttcttgca tcccagaagc cacaacaaga
    15541 ggtcccgaaa cggttattat ttttccttgg ttcacctttt tcctccttta ttttttccaa
    15601 atcatactaa ctaatctata ctgtcaaggt ttaatgtgac tattttgaat agtcagcaaa
    15661 ctatcctatg cgttcagctg ctaacttcac caattttcct gtccttgcat ttcatcagtt
    15721 agctactcat aagcctcaaa cagagtataa gtcctctttg cctaacgtct tagtgttata
    15781 aaatattttg accgacagcc ttttcaacca tggcttgtat gcgtgacagg cctatccctt
    15841 gcgctccttg atgagttggt aatggtatga ctgctggtag aacttgattg tcatagtgag
    15901 tgagggcttc tggaatagct gcagcaatat cttctgtgat ataaataata ccaaagtctt
    15961 ccattgctag ttgacgcaac tggttaatag cgtcttgtgg ttttattact ggaaaagttt
    16021 gaaacccaat catctgaaaa ggtaaaataa catctctgtt accaattacc ccgactttat
    16081 acaatgtttt ggtcatgcta ttggtctcat cctttctatg acacgttctt tgggtaaatc
    16141 attagccaaa gcagccgcta aaagccgtag attttttact tcaaacgatt tagcgagcaa
    16201 aaagcgagca agcacataag gtccatcgac ttgatattta gccttcgcaa ataaatggta
    16261 aaggcattca tcaacaaggt attctaactc agtcgtttga agagtgcctt ggcgaagttt
    16321 ctctgaataa ggttttaggg ctgtcatata gctatcaggt gttacatttt caaaccacgt
    16381 catcagatcc ttatcatctt caagtgtgat aaatgtttta cttggtctac ttgcttcatc
    16441 agataataac tgcatcatga aacttattgg tttattttgc gatttggccc gtctgacggt
    16501 aatcagatta tacaaatcaa tcacaataag aacagcttgt tggaaaacag ggtcctctaa
    16561 tctttgtgct atttgtttca acgccttaaa ataagctaag tcagtaccaa tttctaagac
    16621 gcgtatgtct tgataatctt gatattcggc ccaaatggac tggatttctg ttaccacctc
    16681 ttttggaaac tcatcagaag tcatcgtcct aatcaaatgt tccaaagcca ccaaaggctt
    16741 gtcaccaatt ggtagtaata agtgactcag atctgcttga ctagctttag cttttaacaa
    16801 cactttgaca ttatgatagg tgtaacgcaa ggtaaataat tgtactatgt caggttgagg
    16861 ggtttctgca aaagcccagc gataggtctt ggttagctca gccattaaga tagattctag
    16921 ccgatccaaa tcgttgagat cgtcaacagt taggtgatag actgactggt gcaacagtcg
    16981 agctaaggtt gttgtattgg gagcctgcaa tagcttatca aattgctctt tagtcaataa
    17041 ctctttttct ttgacactga tagtagtgtt taattctaga aatgttggca tcgctagtca
    17101 aacctcctat atctctgaaa aaagcatatc aatgatgcgg gagctttctt ctttaagaac
    17161 tgattctaaa aggtaacggt ataaataatt gtcatcgact tggtctaaac tgactaaaaa
    17221 tcctgcttcc tgaggaatta gctcttgatt atagcttaat tgaggaaacg ctaatctcag
    17281 ctcagcacaa tcataagaac tgaacttttg ccctgttttt tcgccaaaag taacttgcaa
    17341 tggctgttct ggatatttag acaagacttg cttcaaaaaa gccaattctt cttccttaga
    17401 aaagttcgtc atcttctcca aagaagcttc aaatagctcc tttatactgt cttgttttaa
    17461 tgctagtaga gcttgtcttt cttggttttt gagttgctgc tgcgcaacct gaaattgctg
    17521 ttcaagagct tttaactctt tttgacgctt tgcttttaaa tcgtgtagtc cttgctgttg
    17581 acgctcttta aagtcagtat caagactatc tgtcgctatc tttaggcact gttgaccttc
    17641 ttgatgtgct ttttcaagaa cattttgtct taactgtgtt atatcattca cctaatttcc
    17701 cccttttgat agtgttagtg gtgccaccgt tttttaaaat ctagataagg accgttacct
    17761 tatccaattt tatttaagag aataaaggag acgacaaagg caagaatagc ataggtttca
    17821 accatagctg ctaaaatgac acccttcata aaatctttag ggcgcttagc caagatttgc
    17881 ataccagcta cagaaacatt gccttggtgc ttggccgaaa aataaccaac aatagcaatt
    17941 ggaagagata ccaaaaagta agctaatcct tggttaactg aaagttctgg tgtcagtttc
    18001 atccaaatta aaataccaat agcaaagccg tagattcctt gactaccggg taacagttgc
    18061 aagataagcg cagacgtaaa tttttcgggt tcttctttta agagcgcagc tgccgcttga
    18121 ccacctttac cgacaccata agctgagccc atgccactaa gagctacggc taaaacaatt
    18181 cctaaggctg cgaagaaaac gccaccatgt gctgtaaaat aatgtgctaa atgttccatg
    18241 ttaattgtcc tccaaatctg tttcttcatt gacattgaca taattatcag ctaactttaa
    18301 aggattgaaa gcttttcctc caccttcata aaattttcca aaaaactcta cgaaaataag
    18361 acgagcacca tgcacatatc ctgaaagcat tgataagaaa atattgatcg catgcaaaag
    18421 aataaaaata aagataccta ctgtaaagcg cgtgactggt ggaaaaatcc caacaatcat
    18481 gttaaaagcc gctccaatac tagctccaga aagccctaat gccattagac gagtaaagct
    18541 aaccaaatca cttaagtaag agctaatgcc atataaatta tataatccac tacctagacc
    18601 taaaaggctt ttgcttttta gtaaagaaac aaccaaaatc ccaaaggcat tgcccaatgc
    18661 aagccactta ccaataaccg ataagtaagc aaggccagat acattcttac caagaataaa
    18721 taacagcagg cctaataaaa taaaagtcca agctagactt gacgtatagg ccgtagcata
    18781 tgctttcatc cttacttgtt gccatgctcc taacaaaagc ccaaatataa gtgtaacaaa
    18841 cccaaatagc aaagaaacaa ccaaaatagt aatcacatcc gttttagttg ataataatgc
    18901 cacaggtaag tcaaaaccaa agaaagaacc gtaaataagc ccccatatgg ctactgaaat
    18961 agctaaaata ttaaagaagg tcactaaccg tttactggtt ttttggagat taaaaaagac
    19021 caatgcagct agtgtcacag catatagcaa caaaccatag cccaaatcag ctaccatcat
    19081 gccaaaaaaa gtaaggtata aaggagctaa aaaaggtgtc ggatcttttt cttgatattt
    19141 tggcaaagcg tacatttctg taaccaattc aaacggtgca atgtagcggt gattacgtaa
    19201 cttaatggga acatcttccc aatcgtctgg cgtgacatcg taactatcca gataaaacat
    19261 atcacctagt gtcttagtca ttagcccttt taattggtta accgaatcag cttctatcca
    19321 cccttctaag gctattagat gtcttgtacc gagtaattgc tttttagttt gctgccgttg
    19381 atactgacta aggacatagt ctatttcaac ctgtaactgt gccagtatct tttgagactg
    19441 cctaagctct tttagtagac tatctttttc agctagccaa ttcgttagta actctttgtt
    19501 tatacgaagt tgttctgatg gcagtagctg ttctttatat aataagggtt taaactgata
    19561 tttctgtaaa tgaatcgtat cttgtgcttg ccaaaataag acaaggccgt actcaaattc
    19621 tgtatggtat acttcctcaa taaaaagacc tttgtgctgc tttagctgat gataaaaatg
    19681 atcatttgct gtactaggaa tcgttccaac tcttgccgac aaaaaatgaa attgcgctaa
    19741 gtcctgaggc aaaacagtca aggaacgcca cttttctaac tcctgacagt attctgttag
    19801 ctggtctatt ttgttttgca gctgctctag tcgttctatc ttttgtgaca tcattttcaa
    19861 agccgtttga gctgcttgtt gtcgatggcg ttcttcgaac tgtttaaacg aaagagatgg
    19921 cgttttttgt ctcaaggctg ttaactttcc tattggtggt aaaaacgctg ataagctagc
    19981 aaggccgttt tctaactctt gttggctttg taaaaggtat tgtaaagctt catcatctag
    20041 tagaggtttt tgatgcgtca gatcgtattg gacgatttgt ggcaacttga cgttgccttt
    20101 gttaaaagca tcttgccaat gttttagttg cttcatgtca cgaacttcaa ctaattgaga
    20161 ttgttgaagt gtttttaaaa caagatcaag ataatctttt tcaaaaacca ttgccagctt
    20221 tttcatttga ctaatggcca tatgtctcca ccaccttatc cactaactcc ctaacaacgg
    20281 ttagcttatg ctcttctaaa atggcatgaa gggctagctg ttgcgtcgct aacctctttt
    20341 ttgaagcttt ttgttcttga cgattagctt caaaaaacac ctcacgttta gcttctaata
    20401 gtagctgagt ttcttgttcg tactcaagga acagctgctt taactcttct tcttttttgt
    20461 cagctagagc ttttttctta gcatcgtaac tgtcataaat tgttctagcc tcttgttcga
    20521 tactattcat tagtgacaat agggtattca tcacatatca actccttatc tttatctatt
    20581 gctaattctt tgactcacta ggtacttaaa aacaaagcta caagaaaggc tacttttggg
    20641 ggttaatcaa ccagcgacta taagctagag ctaaatctct aacctatcta ctaacagctt
    20701 ttttgagata ggataattgc ttgattaagc gaacagtatc ttcaagttaa gcgttttcaa
    20761 ttctatccat aaaaacaatg gcttagttca gaaaaaggtt agctaaaaac ctgtcaaagc
    20821 agtaagatga cacagaactc taaagctttg tattgctgtc tttcgtgtat tatcttatac
    20881 ttctttaggc atttagtaac cttgatctag ttgacggtaa ggaaccttta ccagccaata
    20941 gccaagccaa tgtgataaca gtataactgc tatcgtgtta aaagtcctgt caaaaagatg
    21001 tttattagtt tctcgcttgt aattcttgtt ttgttactaa acggtaattt ttaaagacag
    21061 aacctccaat ataacccaca attaagctga taataataca tccaagggct gttatcaaca
    21121 ctttagcgac aggattatag gcaaacatca ccgcaaaacc ggcaatcgga gtagctgtcc
    21181 ctggcgtatc attaaccaat ttcattaggg cgatcaaaac accacatgca gcaccaccaa
    21241 cgaaattagt cacataaatc ggaatgggat tggctgacgt cacatctgcc tgagtcaacg
    21301 gttcaatagc aaaagcaata ttgtcttttc tttcacccaa ttttaatcgg taaaaaagaa
    21361 caccattcat aaaagaagag ccaaagacag ataaggcacc tatagccatc ggaatacctg
    21421 tcagaccaag catggctgtc aaagccattg atgacagcgg agctgttgct acaacaacaa
    21481 tcgtaccgcc tagtatcatt cccatgataa tagggttgct attagcactt gaggtcagga
    21541 tgtctccaat agtcaataaa gtactattga tcactggcgt aattaactgc gccaagaaac
    21601 gagttaatgg tgcaccgaca ataataatcg agattaaatc aagcccacca ggaatatttt
    21661 tttccatcca cttgattaaa aaagatacca catacccagc cacaaaacct gggataatac
    21721 ctgttcctga aactgacaaa ccaatcaaaa cggcataacc tggagacaca ccaattgcaa
    21781 tggcaaccaa gatagcagca gctacccctg ataatgagcc atttgctccg cctacttcac
    21841 ttagaaactg aaagcctaaa accttaccaa aaaaagaatc ttgaaaggct tcaactaaaa
    21901 aagaggcaca agctgccgaa gccaaagctc ccattgcctt ggcaccatga ggagccttat
    21961 agttaaacaa gctaaaaata gctaaaacaa gaatcaaaag acttgttcca ataataatat
    22021 ccataatcta ttccaccaat ctatctcatt acataagaca ctataactgc ttcactctgg
    22081 caacagcttc gacttcaatc aaagcttgca aaggaagcgc cgacacttga accgctgtcc
    22141 gaacagggta aggctcttca aacaaatcag tcatgacatg atttaatatt tccacattgg
    22201 tcacatctgt taaatacaca tttagcttat agatatgatt caagtccaac ttttgctctg
    22261 ccaaaataga ttgtaaatta acaaaaacct ggcgacactg tgcctcaaaa ccatctgaca
    22321 attgacctgt cactggatta aggggtaatt ggcctgcggt gtatagaaaa tgtccttcaa
    22381 tcgtataagt tgaataaggg cccattggtt ctgggtagct cttcatatac gaacctcctc
    22441 attgataata tagttaaatt ttacaggaaa ccgcattcac agtcaataat aaattctctt
    22501 tttgataaaa aattattatt aaggtgattg gcaattgttt tttagtctaa aatgtattac
    22561 tatatttgta aataagaaga tagatatagg aagtttgaca tggataaaga aacgctaaac
    22621 tactggaaaa cggttatcac atttcttcac gatgtcttag gtgataacta tgaaattatt
    22681 ttacatgtga ttgataaaaa tgatatctat attggagaac tcgttaatag tcatatcagt
    22741 ggacggtcta aacagtctcc tctcaccacc tttgctcttg atttgattac caataaagtc
    22801 tataaggaaa aagattttgt gaccaattac aaagcaatcg ttagtcctca gcacaaagaa
    22861 gttcggggat ctactttttt tattaaagat aaaaagggta atctcgaggg aatgctatgt
    22921 attaacttag atatttcagc ctatcaagga gtagctaagg acctcttaaa acttgtcaat
    22981 ctcaatttag aacatttcat cccaactgct aaagagccta aaacagtcac accccagcca
    23041 gaagaagctg ttgaaatttt aacctctaac atccaagata ttatcggtca aattattgat
    23101 ccctcgttac tgagacacaa tgtacatctt agccaagatg tcaaaataga cattgttgcc
    23161 aagctttatg aaaaaggagt ctttcaacta aaaggagccg tctcaaaagt cgctgatatt
    23221 ctatgtattt ccgaaccaag tgtttaccgc taccttaaaa aaattgaagc cgatcaataa
    23281 ccaaatcacc ataaaacgcc agttaaaagt atttcagata agcatcacaa tctctgatat
    23341 accgatgact gacgtttttt ttactcaata tgcctttatg gcaagaaaag gctactggtc
    23401 attaaccttc agctatgctt agaggtacac ctgtcgcagc ttgaacctca tcaaaagtaa
    23461 acccttcact gatttcaatt acttggatac catctggcgt tactttaaac acacccattt
    23521 ctgtgataat aaggtcaacc acaccttttg ctgttaaagg taaggtacat tcttttagga
    23581 gcttatgctt tcctttattg gtatgctcca tagctacgat gactttttta gcaccaacta
    23641 atagatccat tgctcctccc ataccaggaa ccattttgcc tggaatcagg taattggcaa
    23701 tatctccatt ttctgcaatt tctaaagcac ccaagacggt caaatcaaca tgaccaccac
    23761 gtataatgcc aaaagaatct gcactattaa agaaagcggc tcctggataa accgtcacag
    23821 gctgtcctcc tgcattaacg atagtcgaat tcggatcatc tgacttagga cctagtccaa
    23881 taaacccatt ttcagattga aaatacactg tcatttcttc aggcacaaaa tttgctactt
    23941 tggttggtag accaatacct aaatttacca aagtaccatc ttctaattct ttggctacac
    24001 gctttgcaat acgattttga atctcttctt tacttaatgc aaccgccata actatactcc
    24061 ttctttaaca atgtaatcta caaaaatgtg tggtgtatga acgcattctg gttgtatggt
    24121 gccgactggt actatttctc gcgcctgaac aattgttgtt tttgcacaag ctgccatcaa
    24181 ttgattaaaa ttattttcag aaccactata ctgtaaattt cccatttcat cagctttatt
    24241 agcaaatatc aaggcgacat ctgcctcaaa tgggtattct aagagatagg tttttccctt
    24301 gatggttttt gtttccttgc cttctgccac taaggttcct acccctgttg gcgtgtaaaa
    24361 gccaccaatg ccataagctc cgatgcgaat tttttcggcg aaggttcctt gaggaataag
    24421 ctcaatcgtc gtttcaccgg cagtcatttg gcgcccagct tctttattta atccaatatg
    24481 tgttgcataa atggttttga attgatgatt agccaccatt tttccaacac cgcgatcaac
    24541 aaaaccagca tcattacaga tcaaggttaa gtcttttgtg cctttgtcaa ccagtgcatc
    24601 aattaacgct tctggtgttc cattagccat aaaaccaccg accataatcg tgtcaccatc
    24661 tttaatatga ctgatagctt ctgctattgc tattctttta ttctctttca tacggttacc
    24721 ttctatcttg ttacgatgat actttgacct tggccaccac caatacaaag cgttgctaag
    24781 ccatgtctca catcacgctt agccatttct gctaataagg tgactaaaat acgagcacct
    24841 gatgctccaa tcgggtgacc caaagcaata gctcctccat tgacattaac tttttcattg
    24901 tcaaaaccaa ggtctcgtga aaccgctaaa gcctgagcag caaaagcttc gtttgcttca
    24961 atcaaatcaa tgtcatcaat tgtcagctga gcctttgcaa gagccttttt cgtagcaggt
    25021 attggtccgc agcccataat acttgggtct acacctgcac ttgcataact agtgatttta
    25081 gctaaaatag ggagccctaa ttcttcagct ttttctttac tcatcaataa aattgccgct
    25141 gctccatcat tgattcctga agcattacca gcagttactg tcccctcatc tttgataaaa
    25201 gcagggcgta actttgctaa cttatccact gtcgttccaa atttagggta ttcatcttga
    25261 tcaatgagca aaggttcacc tttacgctga ggaatagtga caggtgcaat ctcttctttg
    25321 aaacgacctt tttctatggc aagttgggct ttacgttggc tatcagctgc aaaggcatct
    25381 tgttcttctc tggtcagtcc atactgttgc acaatatttt cggctgttat acccatgtga
    25441 taacctgcaa aagcatcact caacccatct ttaagcatgg tatctactac tttactatct
    25501 cccatacgag atccccaacg ttggccttgt aaaacgtaag gtgcttgact catgttttcg
    25561 gtaccaccga ctaaaacaat atcagcgttg cccgtttgaa tcttttgagc acctaactca
    25621 actgctttta agccagaacc acagaccata tcaatcgtaa aagcaggggt atcataagaa
    25681 agccccgcat ttagcgctac ttgccgagca acattttgac ccagacctgc atgtaacaca
    25741 ttcccaaaga tcacttcatc aatggcatca cttttaagac cggtatcagc taaaattttt
    25801 gtaacaactg tcacccccaa atctacggct gataaagatt taaagactcc tccaaaattt
    25861 cctatcgggg tacgataagc agatgtgatc accacttctt tagtcataga aacttctcct
    25921 ttttcattat tgaaacgctt acatttttat tatataatgt gaactataat aaacaaatat
    25981 cgttttttta tatatgctat aactaaacgt tatcgaaaga ggaaaatatg aatatttcaa
    26041 gcttggctta ttttattgag attgttaatt gtgactttaa cttaaccaaa gcagcccaaa
    26101 aaagtcatat ttcgcaaccc gcccttagta gttatatcaa gactatcgaa aaagaagaag
    26161 gagtcgtttt attccagcgt caaaaagggc gtctagttgg actaacctca gtcggcgaac
    26221 gcttttttga aaatgctaag gtggttatcg catcacatga gcaattaatg gctgatttgc
    26281 ggagtgaatc caaaaaatac aaaggagaaa tttcaatcgg tattcctcaa ctcatctctg
    26341 gcattgtttt ttctgagctc attccaaaac tcatcgaaga aaatcccgaa gttaaatttc
    26401 atattgtaga aacgggtgct tatgaactgc aaaaaaaact gtttctaaaa gaagtcgatt
    26461 ttgcgatttt attaacaccc actacactag atgctactat tgctgatatc gacattctcc
    26521 taagagatca actctgcctt tatatgagtc acaaaacctt tcaagagacg tttgatagta
    26581 atcctaacat ctctatcaaa gcattacatc gtcaaaactt agtaactttt gataaaacct
    26641 ttatgattaa tcatcagctt accaccttat ttgaagaagc aaatagtctt cctgtagtca
    26701 aatgttattc tgcctcgtgg gattttttat taaattgcac gcgctattcc tcttacctaa
    26761 caatcctacc aagacctatt actcattttg ctcatatgga cggtttagtg gaggtccaac
    26821 tgaccgaaca tccaaaatgg gaagttgttc tagcctctct caagcacaat aaaacaagcc
    26881 atttaaaaca ttatatcaag cacaccatct tagattattt catgaaccag cgcttctaat
    26941 tgcttgactc agaccttaaa aaaaacgcct gaaggaaaca atcccaagcg tttcatgtag
    27001 ttatttccta aaatacaaat aggtaaatga tggcaatacc tgtgaccacc aagacacaag
    27061 gaatagtata agccacaatt tgattgaatt ttagtttgaa gtttgagaga taagataagg
    27121 cccaaaaagg aactatcaag tttgttgtgg catctcctaa ttgataagcc tgcaaaatct
    27181 tacctaggtc attaccaact tcgatagttg cagggacgat atagggagct tcaatcacaa
    27241 attttgagcc tcctgatggt accgcaatat tcagcaaagc cgagtaaaga taagcaaaga
    27301 ccggccatgt tgtcccattt gaaatagcga caaagaaatg ggaaatctct agtcctagac
    27361 ctgtactttg aatgattcca aaaataccag cgtaaaatgg aaactgaagc accaagcccc
    27421 aagatgacat gaccccatct ttgaataagg aaccataata ttctggtcct tgttgaccac
    27481 aaagaagcaa ccctaagcct aaaaataaaa agttaaaact attgagatct agaccagaca
    27541 agcccaccac caaaaaatga taaaggctat agctaacaat ggccccacca acaagataca
    27601 tcactaagcg agatgcgttc atcttttcag caggtgtgtt tcttgcaata acaacatgtg
    27661 aagcggtatc aagactatgg tgatagatct catcatcaag ttccatgatt ttagtttcat
    27721 cttttggatg cgccaataaa gcaaagcaaa gcggtaccag catacacacc actaaaagac
    27781 tgataaatgg aagattcaaa actgattctg tcagaggaac actttcagga acaacctgtt
    27841 tataagcatc tgcgacacta tttcgcaaat aatctggagt agccgaataa agcaccgcag
    27901 caccagataa accagaagta gctggtaaaa aggtaaaaaa taaagtagca acaaacaaag
    27961 gtgtatgcac cttaatccct ttttgcctag cctgaacaag caactctttc ccaaacacaa
    28021 tggcaaccat cataccaaga ccccagtgta aaaagccaaa gatagagcct actacaagag
    28081 aaaaaataaa aatctgagtc ctggtttgag gcagtttggc aagggactta aacatcttat
    28141 gagcaggtgg agaactcgct acagcattcc ctgtcgcaag taaaatagtc atctgcatgg
    28201 caaaggacaa cagcccccaa aaaccattta cccagccata gataatcccg cccgtctttt
    28261 ccgtaccaat aaagggacta tccgtcatca acacagacat agtaacgact aaaaaggtta
    28321 aaataaaaca gataaaaagc gattctggca tccatttcat aaagccatca atatagcgat
    28381 ccataaacct ttttttggtt ttgatgttat tcatgttgtc aattcctttc acattgtcca
    28441 caagcacttt tgttcttttg atcagtaacc tgtcgataat actaataagc gtttatttag
    28501 ttcatttagt tatcaataag tttaaaccca caaaaaacac ttttgttccc tttttattat
    28561 gacaacgttt tcataaacaa acaactatga tttttttatt gcttccataa cccttattta
    28621 taacaaaaag aatggagctt cactca
//
LOCUS       DAUGOH010000020        27794 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUGOH010000020 DAUGOH010000000
VERSION     DAUGOH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27794
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.020"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..1271
                     /gene="rocA"
                     /locus_tag="VH957_000998"
     CDS             <1..1271
                     /gene="rocA"
                     /locus_tag="VH957_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEQ8558917.1"
                     /translation="SAIPLRLKNIFYLSLSMVLFQVVFWAFFPDHFILDVVMLAQFLF
                     FALIALYYGKSIKAKFLMFYAFFPLVSISLVKRFIVFFVMPLFGMPYSVVKHNTLLIY
                     SITCFSIFLIYRCIQVFHFDFSTWRQYFQSHRASKLLVFTNSSMALYYLCVQGIDVMS
                     PSLSGLATTTARSIIVLFYFILFLTLLIHLERYVKQNSIEAIVQQKEYRELINYSQHL
                     GLLYQDIQELRQLLTTVSSRLKIGIEQNDISIVRLTYEGILNAEKNNAKDDRLDLTCL
                     DKLQVEAIRHIVLAKLIEAKNKKLKVEVSIPNCIATFFLEVVDFTKLLSFLLDNAIEM
                     SLETKQPCLSIAFLDQNHKLVIVIQSSTKQGQDDSQSVFAIPALKKRDDWQFDLRNVT
                     TILNRYDYLTISSQIHDGILTQLIEIAKPD"
     gene            complement(1372..4077)
                     /locus_tag="VH957_000999"
     CDS             complement(1372..4077)
                     /locus_tag="VH957_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEQ8558918.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTNP
                     NFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDKWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDDSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKTYHFGQRFPKEVYQEAQEYLARLSQ
                     SFQIIDTSGQVRPEAEILGTSIAFDYDLPKRSFREPYFAIKVRLRLPITLPAMSWKTL
                     ALKLGNETTPSETVSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPNHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPVSADKLLQA
                     EMEAIIDITERQSGRSQEKAELTLTTLIRMEKNNPRLQFTTSFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPNAAFWKNPSNPQHQECFVSLFDGEKGVTIGNYGLNE
                     YEILPDSNTIAITLLRSVGEMGDWGYFPTPEAQCLGQHSLSYSFESIDRQTQFASYWR
                     AQEGQVPILVEQTSHHTGSLRAEHSYVTGADDQIALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(4092..5378)
                     /locus_tag="VH957_001000"
     CDS             complement(4092..5378)
                     /locus_tag="VH957_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEQ8558919.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANGKGHQTDRTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTIFSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            5511..6551
                     /locus_tag="VH957_001001"
     CDS             5511..6551
                     /locus_tag="VH957_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8558920.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            6602..8296
                     /locus_tag="VH957_001002"
     CDS             6602..8296
                     /locus_tag="VH957_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8558921.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDMPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAELTVKHFFNRQLDKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGRKRM
                     NTYMYAPKDDDYQRKQWRDLYPEDWVTYFKGLLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAIYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQSDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKNVSTLSAWVDELVELVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            8321..9763
                     /locus_tag="VH957_001003"
     CDS             8321..9763
                     /locus_tag="VH957_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8558922.1"
                     /translation="MLAFPKDFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPTLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQVYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAELSDGR
                     IGTILNLTPAYPASQSEADTAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDAYLMPGRRMN
                     VDKGWEIYPEAVYDIAVKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIRF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(10374..11252)
                     /locus_tag="VH957_001004"
     CDS             complement(10374..11252)
                     /locus_tag="VH957_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8558923.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAVSAPGAVNKEKGIIEGASAIPYIHHFKIKEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVIGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALTEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            11448..12398
                     /locus_tag="VH957_001005"
     CDS             11448..12398
                     /locus_tag="VH957_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8558924.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            12408..13334
                     /locus_tag="VH957_001006"
     CDS             12408..13334
                     /locus_tag="VH957_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8558925.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            13415..14860
                     /locus_tag="VH957_001007"
     CDS             13415..14860
                     /locus_tag="VH957_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8558926.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIDDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            15166..15771
                     /locus_tag="VH957_001008"
     CDS             15166..15771
                     /locus_tag="VH957_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEQ8558927.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTITYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            15761..17485
                     /locus_tag="VH957_001009"
     CDS             15761..17485
                     /locus_tag="VH957_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8558928.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGFSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADKVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMEKRLQDHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            17485..18969
                     /locus_tag="VH957_001010"
     CDS             17485..18969
                     /locus_tag="VH957_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8558929.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            18899..22405
                     /locus_tag="VH957_001011"
     CDS             18899..22405
                     /locus_tag="VH957_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEQ8558930.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTDYQ
                     YHYIDQEGRKQPFNQGWRFLMADVTCAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDRLHEEHSDWLLYGSET
                     VSAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKASTPHILITSYQHY
                     LPLPLQVCSQAFDFKKGDDIFLPQWFQVKDAQGSFVKKAFPMTWYLKEKIFAEPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            22543..23421
                     /locus_tag="VH957_001012"
     CDS             22543..23421
                     /locus_tag="VH957_001012"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8558931.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            23656..24411
                     /locus_tag="VH957_001013"
     CDS             23656..24411
                     /locus_tag="VH957_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEQ8558932.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            24464..24802
                     /locus_tag="VH957_001014"
     CDS             24464..24802
                     /locus_tag="VH957_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8558933.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEV"
     gene            24804..25109
                     /locus_tag="VH957_001015"
     CDS             24804..25109
                     /locus_tag="VH957_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8558934.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPKDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(25509..26582)
                     /locus_tag="VH957_001016"
     CDS             complement(25509..26582)
                     /locus_tag="VH957_001016"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEQ8558935.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQTKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKSLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKHIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(26638..27390)
                     /locus_tag="VH957_001017"
     CDS             complement(26638..27390)
                     /locus_tag="VH957_001017"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEQ8558936.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(27630..27700)
                     /locus_tag="VH957_001018"
     tRNA            complement(27630..27700)
                     /locus_tag="VH957_001018"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27666..27668),aa:Thr,seq:ggt)
BASE COUNT         8052 a         5341 c         6056 g         8345 t
ORIGIN      
        1 taagtgcaat tccgcttcgc ctgaaaaata ttttttattt atcacttagt atggttttgt
       61 ttcaagtagt tttttgggct ttctttccag accatttcat tcttgatgtt gtgatgttgg
      121 ctcagtttct tttctttgcg cttatagccc tatactatgg taaatcaata aaagctaagt
      181 ttttaatgtt ttatgccttt tttccactag tgtctattag tttggttaag cgatttattg
      241 tattttttgt tatgccattg tttggtatgc cttattcagt tgttaaacat aatacactac
      301 tgatttacag cattacttgt tttagtattt ttttgattta tcgctgcatt caagtttttc
      361 atttcgattt ttcaacctgg cgccaatatt ttcaatcaca tagagctagt aaactattag
      421 tgtttactaa ctcttcgatg gctctatatt acttgtgtgt ccaagggata gatgtgatgt
      481 cgccttcttt atcaggactt gctacaacga ctgctcgttc aatcatagtg ctcttttatt
      541 tcattttgtt tcttacttta ttaattcatt tagagcgtta tgtaaaacaa aactctattg
      601 aggcaattgt gcaacaaaaa gaatatcgtg agctgattaa ttatagtcag caccttggat
      661 tgctgtatca agatattcaa gagcttaggc agctattaac taccgtgtcc agtcgtctta
      721 agattggaat cgaacaaaat gatatctcta ttgtgagact tacttatgaa ggtatcttga
      781 atgctgaaaa gaataatgct aaagatgaca gacttgattt aacttgttta gataaattac
      841 aagttgaagc aatcagacat attgttttag ctaaattaat tgaggcaaaa aataagaagc
      901 ttaaggttga ggtatcgatc cctaattgta ttgcaacgtt ttttctagaa gtagtagatt
      961 tcactaagct attgtcattt ttgttagata atgctataga aatgagtttg gagacaaagc
     1021 aaccttgctt atcaatagca tttctggatc aaaaccataa acttgtcata gtcattcaaa
     1081 gcagtactaa acaaggacaa gatgatagtc aaagcgtgtt tgctataccg gctttgaaaa
     1141 aaagagatga ctggcaattt gacttaagga atgtcacgac cattttaaat cgttatgact
     1201 atctcacaat tagctcgcag attcatgatg gcattttaac ccagttaata gaaatagcta
     1261 agcctgactg atgttaaagg tattaataat cactcaaaat caacttaaga gtctgagaca
     1321 atagtcccag actctttttg aatatgttaa tctattacta atgataatag tttattgttt
     1381 cttccaagct agagttaaaa tttccgcttt gccaagttgg ctgggtgtgc tttgcttgct
     1441 gtctttttct aacaaattag tgaccttggc attgtagttt ggcaggctta ggctaaagtc
     1501 acaagtttta tcgtttgaga gattatagct gcgcgtgata agggcattgt ctgctaagcg
     1561 acgtttgaaa gctgttagag cgatttgatc gtctgcacca gtgacatagc tatgctctgc
     1621 tcttaagctt cccgtatgat ggctggtttg ttcgactagg ataggaactt ggccttcttg
     1681 tgcccgccaa tagctggcaa attgtgtttg cctatcgatg ctttcaaaac tataagatag
     1741 gctatgctgg ccaagacact gggcttcagg tgttgggaag taaccccagt cccccatctc
     1801 accaacagaa cgtaagagag tgatggcaat ggtgttgcta tctggtaaaa tctcatattc
     1861 gttgaggccg tagttaccaa tagtgacccc cttttcacca tcaaagagac tcacaaagca
     1921 ttcttggtgc tgtgggttac ttggattctt ccaaaaggca gcatttggat gatttggacg
     1981 tttgacagtt tcaaaaatac tatcagctag gtgatggtct gtcttaaggt gcgttgggaa
     2041 taggacgcgc aagcgatgat tagtcatttg gttatcaaaa cttgtggtga attggaggcg
     2101 aggattgttt ttctccatgc ggataagggt tgttaaggtt agctcagcct tttcttgtga
     2161 acgtcctgat tggcgttctg tgatgtcaat gatagcctcc atttcagcct gtaagagctt
     2221 atctgcggag acaggaatgg caaaggtttg ctggatttca agttcagcaa cttgagcggt
     2281 gttgctaatg atgttaagct tggtggtccc ttggtccgca tagaaaggtt ggtcatgatt
     2341 tggttggcga gaaatatatt catttccaat atcgccacaa tcttcaaacc gcaacaggtc
     2401 ttgatagatt agtccagatt gtttatcggt gatggttaga cgaccatcgg tttgtatcat
     2461 aacttttaga aacccatttt caaggcactg attactgtca tcgtagaggg aaacggtttc
     2521 tgaaggagtt gtttcatttc ctagctttaa tgctaaggtt ttccaagaca tggctgggag
     2581 agttattggt agccgtaatc tcactttgat ggcgaaataa ggttcgcgga aggatctctt
     2641 gggcaaatcg tagtcaaaag cgatgcttgt gcctaaaatt tctgcttcgg gtctcacttg
     2701 tccactagtg tcaataattt ggaaagattg ggagagtctt gccaaatatt cttgagcttc
     2761 ttggtaaacc tctttaggaa agcgttgacc aaaatgatat gttttccagg tcaggctgag
     2821 ctcagcaaca cttgttttgg aatggccgct ggtattaaat aagacgaagg gttggctatc
     2881 cattggaaaa tccctggtat caatggcgtc agcaatttgc ttagcagctt cttttgctaa
     2941 atagtgtccg acttcatagg ctttttcaaa gcgcgtcatc atttcccgat gaacgctatc
     3001 aacactacaa ccacagatag aatcatgagg gtgattttgc atgagggttt tccaagcgta
     3061 acgcagttgg tcgtgagggt aggtacttgt tacctcataa gccattgctg ctaagggttc
     3121 ggtgatgttt tcgagttggc gagagactct ggtattagcc tgtttgaggt aaatacgagc
     3181 agaagccgtg ttagctaggg tataccagcc atcggtttct tgactggtaa tctctccttg
     3241 gacggttgaa aggttctctg gtaaatcatc tgcgagatca gccaagtaat cttcaaagca
     3301 ggaatgcaca aattcgtagt caggatagag ttggttggct aaggcgattg ccttggtgac
     3361 atcaagttgt acgggttgat gatcacaccc gttcatcatc agaaggtgct tggttgaggc
     3421 gaagcgttcg gcgtcagcaa gttttttatc ccaaaaaaga cgcgcctcag cttctgttgt
     3481 cgggatctca ttgccattgc tgtaccagtt ggcgaagagg agtccaagaa tacgactgtc
     3541 atctggtcct tgccaactga tttcagagaa ttgggagctg tatttttcac tggtatctac
     3601 ttgattgtta aatccagttg gacgaatgcc acgaccaaag gcagcagctt gtaggccggc
     3661 ttttaacatc agctgtggtg tttgtcccat atttccaaag gtgtctggaa aataaccaag
     3721 tggcacacta gcgccccatt tgtcacaatc ctccttgcca atgagcatat tgcgcacatt
     3781 ggactcgctg ctggtcaaaa aatcgtcctg taagatatag aaaggtccga tacggagttt
     3841 tcccgaagca atggcttgtc taatctcagg ttctcgttcg gggcgtactt ttaaataatc
     3901 atctaggata atggtttgac catccaaatg aaaactatga aaattaggat ttgtttgaaa
     3961 aacttctaac aggtcatcta ttaagttaat cagacgcatg tggtgttgct cgtaagccat
     4021 gtaccactcg cgatcccagt gactgtgtga aataatatgt acttttttgg ttgccatagt
     4081 ggcctcactt tctaaggagc aatgctaaag ccaagatagt caagaagtag ttcacagaac
     4141 atcatgttag cccaagagaa ccactcacgg gtgtattgat aaggatcatt gacatcgaaa
     4201 ccctcgtgca ttaagtgggt accagcatct gttgccacaa gcaaatcaag catctctttt
     4261 ttactgtctt ggtcaagagc ggtcaatcct tgtaaggcaa gggcgatatg ccagatataa
     4321 ttttctggtg tatgggaaga accgatgcct gctgctgcat ttccctgata ataataaggg
     4381 ttttcttggc tgaaaatggt gcggcgcgtt gccagataga tagggtcatc tttagcgcaa
     4441 aaaccaaggt aaggtgcagc aaggaggctt ggaatattag catcatccat gatggaaaac
     4501 tgtcccagac catccacttc ataagcgtaa atggtttctc ccttgctgtt ttgaacaagg
     4561 gcatggtctg caatacccga ttgaatagct tctttcagct gcttggcacg agtagctact
     4621 ggttcattgt gaaaaaggtt gttatataaa tcttctagat aggaaagcac aaccactgca
     4681 aacatatttg aaggaatgag gtaaccatat tgacaagcat catcacttgg tctaaagcct
     4741 gaccaggtca tccctgttgg tgcgacagga cttccttttc cagcatgtgt tagggtatct
     4801 tctttgcgcc aagtatcgcg ttcaaacaag taaggagact gggcgtggtc ttgctcaact
     4861 gtccataggt caagaatgag ttctacccca cgatgaaaat cgtcattaaa ctgatcggtg
     4921 cttcctgttt cacgatagag caagtaagct agctgaatag ggtagcagag ggaatcaatc
     4981 tcatatttgc gttcccaaat ccaagggttc atttgggtac gatctgtttg gtgtcctttt
     5041 ccgttagctt cttcgttgaa ggcattggca tagggatcga tacaaatgta gcggaattgg
     5101 cgtttgacca aaccggcaat aatctttcta atttcttcat cttccttggc gaggaagagg
     5161 taaggtttca tttgcgcagt ggaatcacgt aaccacatgg caggaatatc tcctgtcaag
     5221 agaaagctag tgccatcttc gtaggttttt agggttgtct ctaaggtatt ggtaaagctg
     5281 gttttgaaat taagagccca atcagggtgt tggtctccac aaaggctttc caccttggcc
     5341 ataaattggc tgacgctagt tgggattggt cgtgtcatat catatcctcc aaaaagatat
     5401 atcatttatc ttcggtttca ttataaatga taagttaagc tttgtctata agtttttgaa
     5461 aaggtttaca actctttttt gacatgctat actgataacg ggagtaaaga atgacaaaat
     5521 tattatacaa aaagatatat catttcatta aagagcagat agcatcaggt cgtttgcaaa
     5581 ttggtgaccg cctacctact gaaaaagaat tgtcagaaca gttctcggtt agccgtatta
     5641 cttctaagcg agcgcttgta gaactggagc aagaaggctt gattacgaga agtcgtggga
     5701 aaggaagctt cgtagctaaa aagcaagtga cgtcccctga agcgaataag gatttattgt
     5761 tgattcttcc ttttgcttct gattatgaat tgggagatta tgctaaggga attatgacct
     5821 ccattgctga aacaggttac cgtctcatgg ttcaattggc cagtacagta aggttagaca
     5881 ccctgtcaga ctatgctggg attatttatt atcctgaaga tgtcaatcac agtattgatt
     5941 tcctgtttta ctgcgaccat catcacattc ctctagtctt gttggataaa tctctagatc
     6001 tttttcagtt tccgtctgtt gtagcggata ataaaggcgg tgcctgtcaa ttgactcagc
     6061 acttgattga gcaaggctgt gaccagatta gttttgtggc aacaggctct tttggagaag
     6121 tatcatccgt tagagaccgt tatttgggtt acttagcggc aatggcagaa tcgtctctaa
     6181 aatcccatta ttttcctaag acagagactg aaacaacaga tgcttatttg gaccgtctgg
     6241 tgaaaacctt atcggagacg acagccacta aaagggggct tgtcgtggaa aacgattggt
     6301 tggctattca gctgattcaa aaaatcacac aggtaggctt atctattcct gatcaagtcg
     6361 ctattgtagg ctttgataat agtcaagcct cccgtttgtt gagtcccaaa ttaagcacag
     6421 cagctcaaga tttttaccaa atggggcaag aagcagctaa agtcttgttg cagattattc
     6481 atgagccaga ccaagcagtg gtgtcttgcc agttacctgt tcaagtattt atcagagaaa
     6541 gtagtcacta aaaaagacgt tactagcatg agctggttag ctcaggtaaa ggagaccaga
     6601 aatgaccatt tatcacgcct taaaggatta tcaagaagtc atgacaagag gagactatct
     6661 tgtctttgac atgccgttga catgccgctt tattggccgt tttttccgtt ttgaaaatca
     6721 aaaagcccta ctggcagaat tggcaacgtc aaagtatttt cagtggattg aagaaggcca
     6781 agcagagttg accgttaaac atttctttaa ccgtcagctg gataaggatg cctttaccct
     6841 gaaggtttca gaagataagg aaattattat tgaaagccaa aaccttagag gttttcgtta
     6901 cgcccaagaa gctttgctta aagtgatgac tttcaaaggg gataaacttt atttaccgat
     6961 tgtatctgtc aagcatagtc cttcttttgc tatgcggggg ataattgaag gcttttacgg
     7021 aacaccgtgg acacgagaag agcggttaga ttgcctgcgt ttcattggac gtaaaaggat
     7081 gaatacttac atgtatgctc cgaaagatga tgattaccag cgaaaacaat ggcgcgatct
     7141 ttatcctgag gattgggtga cttatttcaa agggctactt gcagtagcca aggaagaagg
     7201 gattgatttt tggtatatga ttagtccggg acttgatttt gattatacca aggaagctga
     7261 ctatcagttg ctctatcaaa aattgcaaca acttctagcg ttaggtgttt gtcattttgg
     7321 gcttttgctg gatgatattg actaccaaat tgtagatgct gttgagagac gattcaaaaa
     7381 gactgcctat gcccaggccc acttggcaac tgaggttcat cactttttaa accaacaaca
     7441 tgcggcgcca gaattggtga tctgtccgac agaatacgac aaccaccatg attctatcta
     7501 tttgcaagag ctgtcagaaa ggattcctaa agaagtcgcc tttttctgga caggcccaag
     7561 cacgctagcg agtcaaatct cgcaagcaga tattgaaact atggcagcga tttaccaacg
     7621 tcctatcatc atttgggata atattcctgt taatgattat caaaaagatc cagaacgtct
     7681 ctttttaacc ccttttgcta atcgctcacc atttttatgc caatcagact atcaggtcaa
     7741 ggggattgtt tctaacccta tgattagttg ggaattatct aagctgacct tgacagacat
     7801 gagccattat ctgtgggatg ctaaccgtta tcagcctagt cattcttggc tagaaacctt
     7861 aacagactat acagaagata ctgaattagc cctagcttta caggcatttg cttggcataa
     7921 tggcaatcgt catctgcaca gggaccttcc ttttgaagtg gaagaagctc tcctggctaa
     7981 gaatgtatca acgttatcag cttgggtaga tgaattggta gaacttgtca ataccttgag
     8041 aaagctagat aagccagcgt ttcaacaagc tattgctcct tggtttgaac gtgtggccaa
     8101 agaccaagat ttttggcagg ctatgttaaa tcaggagcct cagttggaaa cactctatgc
     8161 tgacttacaa gaagataaac accgcattgg aagtgacatt ccaagtcgtt actatcgcat
     8221 ctactatcaa cagcaagata aactaacagc taatcaaggt caagttaccc aagcaagacc
     8281 tgaagattat gcttagtcat acgagctaga aaggaatgat atgttagcat ttccaaaaga
     8341 tttttggtgg ggaggagcca cttcaggccc tcaaagtgag gggcgttttg ctaagcagca
     8401 ccgcaatctc tttgattatt ggtatgaaga ggagcctacc ttgttttacg attacgtggg
     8461 acctgatacg gcttcggatg cctatcatca gattgaatct gatttgacct tgttagcttc
     8521 actaggtcac aattcctacc gcacctccat tcagtggaca cgtttgattg atgattttga
     8581 gcaagcgacg attaatcctg atggccttgc ttattataat cgagtgattg atgcttgctt
     8641 ggccaatggt attcgtcctg ttattaattt gcatcatttt gacctgccaa ttgccctcta
     8701 tcaagtctat ggtggctggg aatcaaagca tgtcgtggac ttatttgtcg cctttagcaa
     8761 ggtttgtttt gagcagtttg gtgatcgggt taaggattgg tttgtccaca atgaacctat
     8821 ggtcgttgtg gaaggctctt atctaatgca atttcattac cctgctatcg tggatgggaa
     8881 aaaagcagtc caggtcgcct ataatctagc cctagccaca gccaaggtta ttcaagctta
     8941 caggcgaggt ccagcagaac ttagtgatgg gcgtattgga accattctca atctgacgcc
     9001 agcctaccca gctagtcaat cagaagcgga tacggctgct gcgcattttg cagaactttg
     9061 gaacaatgac ttgtttatgg aagctgctgt tcatgggaaa ttcccagaag aattggttgc
     9121 ggtattgaaa aaagatgggg ttttgtggca gtcaacgcca gaagaattgg ctcttattgc
     9181 tgagaataga gtggattatt tgggattgaa tttttaccac cctaagcgcg tgaaggctcc
     9241 ggatgtcatt ccagtgatta gcccatcttg gagtcctgaa tggtattatg acgcctacct
     9301 gatgcctggc cgccgcatga acgtggataa ggggtgggaa atctatcctg aggctgtcta
     9361 tgatattgct gtcaagatgc gagaccatta cgacaatatc ccttggttct tatctgaaaa
     9421 tggtgtaggg atttcaggag aagaccgtta ccgtgatgaa actggtcaga ttcaagatga
     9481 ttatcgcatc cgatttttga aagaacattt gacctacctc cacaaaggaa tagaagcagg
     9541 ctcgaattgt tttggatacc atgtatggac gccaattgat ggctggtctt ggctcaatgc
     9601 ctataaaaac cgctatggcc ttgtggaaaa taatatccat acccaagtgc gacgacctaa
     9661 agcttcagct tattggttta aaaaagtagc tactcataac cgcttgattt cattagaagt
     9721 aatggaggag tttggaggct ctgcttctca cctcagtgat tgaacgtgtg aacgtctcct
     9781 ttgagacaag tgaataatga tgttaccaat gattaaacaa gggccttttt cctcatgtta
     9841 agaggatcga ggctcttgta tttctttgga aggtgttggt atttgccgaa ctagatataa
     9901 gcgttctgtc tggtttggca tcatctatcc atcttgggta atttggctct tcaattcttt
     9961 agagtatctt ggctaaggat gcttgttttt catcttggta ttttaggatt ttctttcata
    10021 tttttggacc agataaaagc ccctcatggt ttctagtgac tgtttgttat gtcactgtcc
    10081 acgataaggg gactatatga gtgagttatt aagtgaggct ttgcttattg gcgataacta
    10141 gcatagcttc taatagctcg agtattaact gatgaccaat gcctttgaca gaagcgtcag
    10201 caacaacgac atcaacaaag ggaccaggca tcaggctgcg ttcatcagca gagagtcatt
    10261 taggcagaaa gccagtatcg ttgtagctaa tcagcaatcc ttttaggatg tctttgtaga
    10321 tgtcagaggc gattagggac aataggggat aagagggatt tagcggtcca tggttaggcc
    10381 tccttgtgtt cttggtaaaa atcaatggca gctccaagaa gattggcttc gtttttaaag
    10441 tgacaaatgg ctaattgggg tctaaggtcg gagatttcga cggcttggta gagtttgtct
    10501 agttcagctt caatcgctga cagtagaaag tcagcttggg aaacaccacc cccgattaaa
    10561 atcagttgag gatcaaaggc gtgttgaatg ttaaaaatac cgatggctaa actttggaga
    10621 aagacctgcc tttctttgag tgctagggga tctccttgtt ctgtgagggc aaggacagct
    10681 ttgccagtat aatcttttcc gttattgacg attgcactat agcgcttggc catattcaca
    10741 acagtgccta attgactaaa ggtttggtag cggtcgttca tgatcatgaa accaaattcg
    10801 cccccaaata agtgggcacc atggtaaatc ttgccatcaa tgaccaagct tcctccaact
    10861 ccagtaccaa taacgagcat ggctaggcta ctagcgcctt ttcctgcccc taaggtagct
    10921 tcagctaagg cggcacaatt ggcatcattt tcgatagaaa tagggtaatg tagccgttct
    10981 tctaaggcct cttttatttt aaaatggtga atgtagggaa tagcgctggc accttcgata
    11041 ataccttttt ccttgttaac cgctccagga gcactaacgg caatacctga gaaatggtaa
    11101 gcagagtaac gagcaacttc ttggtcgagt aattggtaaa acttttccag actagaggga
    11161 gtgggaaagc tgctttgctg gcttaattgg ccattgtgac agagggcaaa tttaagggaa
    11221 gtgcctccta tatcaataca taacaagctc atgaggtgtt ctcctttatt atagtagaat
    11281 agacgatcat gtctcatctt agtatgacag atttaaacaa caatgaaaag gctttctaag
    11341 cgattctata ctttgtgtta tcatacctat aatttgttgc tttcaaataa tgaaagcgct
    11401 tgatatactg taactataac gtgattaaca caaagggagg ttgggaaatg acaagacaaa
    11461 ccaacaaaaa gacatccttt tggaaaaatg tgattaaata ccgggcctta ttattaatgg
    11521 tattaccagg tttcatctgg ttcatctttt tcttttatat tccagttttg gccaatgtgg
    11581 ttgcttttaa agattttcat tattcagcag ggggctttat ggaaagtttg aaagagagcc
    11641 cttgggttgg tttggctaac ttcaaatacc tctttgcttc taaagatgct tggttgatta
    11701 ccagaaatac catcgcttac aatgtgattt tcttactctt taatgttttc tttgcgattg
    11761 cttttgccat tatcatgagt gagttacgaa ataagcgaac ggttaaggtc tatcacacca
    11821 tgtccttatt gccttatttc ttatcatggg tggttattga atactttgtt tctgcctttt
    11881 taaatacgga taaaggtttc attaatcagc tcttgactgg aagtggagca gatccaatca
    11941 agtggtattc caatcccact tggtggccct tgattttact ctttatgagt gtctggaaag
    12001 ggctaggcta caatagcatt atctactatg cttcagtcaa agggatttct gatacttatt
    12061 atgaagctgc tatggtggat ggtgcaagca aatggcaaca aattaggaac atcaccattc
    12121 cacaattatt gccaatgatg tctatcctat tgatcattaa tattggtaat atctttaaat
    12181 ctgatttcgg acttttctac gttattccca aaaattcagg cccactttat gacgtgacca
    12241 gtgtgttaga tacctatgtc tacaatgcct tgactgctac aggagatatt gggatggcat
    12301 cggcagctag cctttatcag tcagtagttg ggaccagcat cttgttagtc accaatgcga
    12361 ttgttcgtcg catggaccct gatgcagcct tgttttagga ggaaaacatg gagaaaaaga
    12421 aaaaagtcga aaaggttaat gttagaacct ttgatcgaaa aaccaatgct atctttaata
    12481 ttctgattgg tctgtttgcc atctcttgta tcattccttt tatcttcgtg attattattt
    12541 ccttcactga tgaaagttac ttgattaatc atgggtatag tttttttcca gatgtctggt
    12601 caactaaggc ttaccagtat atttttcaag gagccatgtc ccatagaatc atgaggtcat
    12661 ttgggatatc cgtgtttatt acagtggtgg gaacctttat taacacgacc atgacatcaa
    12721 cctatgctta tgcgatttca agaccttatt tcccatacag acgttttttt actgtttatg
    12781 cacttatcac catgctcttt gcaccaggga tggttgctaa ttacttggtg gtcagcaatc
    12841 tccttcattt gaaggatacg gtttgggctt tgattttacc aatggctctg ggcccatttg
    12901 gcatcttggt catgagaacg ttctttaaaa agacagttcc agatagcatt attgagtcgg
    12961 ctcgtatgga tggggctagt gaatggatga tttttatgaa aattgttctc cctttggctg
    13021 ttccagggat tgctaccatc agtttatttt ctgccttaac ttattggaat gattggttta
    13081 acgccttgct ttatgtgcaa agtgaaaacc tctacccaat gcagtactta ctgatgaaaa
    13141 ttcagagcaa cctacaggcc ttggcacaaa atgctggcat gagtgcacaa atggcagata
    13201 gcttagcatc gctgccaaaa gaatcagttc gtatggctat cgtggttatt gcaaccttgc
    13261 cgattgcctt gacttaccca ttcttccaaa agtactttgt cggtggtttg accattggtg
    13321 gggtgaagga ataggactta aggaactggt cacaagacca gattttatct aatcattagt
    13381 aacaaaagaa aacatttttt aggaggcttc acttatgaaa aagtggcaaa aaatcgtgtg
    13441 tgtgactgga actgtgcttg cagcgtctag tttagcagcc tgcgaaagca agtcagcatc
    13501 aaaggatagt gatgtcaaat tattgatgta ccaagttggt gacaaacctg ataacttcga
    13561 tgaattgatg acaattgcta acaagcgcat caaagaaaaa acaggtgcaa cggttgacct
    13621 tcaatacatc ggttgggggg actgggatga taaaatgagt accatcattg cctctggtga
    13681 aaactacgac attgcttttg ccaataatta tgtggtcaat gcacaaaaag gtgcttttgc
    13741 tgatttgaca acgttaatgc caaaatacgc taagaaaacg tataaaaact tagacccagc
    13801 ctatattaaa ggaaatacta ttgacggtaa actctatgcc ttcccagtag atgccaacgt
    13861 ttatgcccaa cagatgcttt ctttcaataa agaactagtg gacaaatatg gccttgacat
    13921 ttcaaacatt aagtcctatg cagatgctga aaatgtcttg aaacaattcc acgaaaaaga
    13981 accaaataca gcagcttttg ctattggtca agtctttagt atgtcaggtg actatgacta
    14041 cccattaacc aaaacccaac cctttgctgt gaaaattgat gaaggcaagc caaccatcat
    14101 taatcagtat gaagatgagt cctttaaaaa caatctccgc ttgatgcaca aatggtataa
    14161 agaaggtttg attccaacag atgcagcgac caatacagaa ggttatcccc ttgaaggaaa
    14221 cacttggttt atgcgtgaag aaacccaagg tcctatggac tatggcgata ctatcttgac
    14281 caatgctgca ggaaaagaca tcgtgtctcg tccattgact aaaccgctaa aaaccacatc
    14341 acaagcacaa atggcaaact ttgtggtatc aagcgtatct aaaaacaaag aaaaagcagt
    14401 tgaagtcctt tctcttctta atagcgatcc cgaattgtta aatgggcttg tttatggtgt
    14461 cgaaggcaaa gcttgggaaa aaattgacga caagaaaatc aaactgctcg atggctatca
    14521 accaaaaatg cacatgggtg cttggaatac tggtaacaat aaaatccttt acactcaaga
    14581 atctgttact gacgacatga ttgctaaacg tgaccaatca atcaaggatg ctaaagaatc
    14641 tccaatcctt ggtttcactg ttgacacaaa agttatcaaa acggaattgt caaatatttc
    14701 aaatgtcatg aaccgatata aagcaagtat caatactggt acagtggatc ctgacgaagc
    14761 ccttccaaaa cttcttgcag acctcaaagg tgctggttgg gacaaggtgc aaaaagaagt
    14821 tcaaaaacaa ttggacgact ttgtagctaa agacaagtaa ggcattcatt ttcttgatta
    14881 taagttgagg gctgggaaat ctcagctctt ttcttctgat gagtggaaaa aacggatcat
    14941 caaataagtg gaagttataa agggagaaaa attaatgtaa ataatgttac tactcttagt
    15001 aaagcggttt ccaaaagcct ataaagtgtg ctatattaga agagtctaaa ctattaatca
    15061 gagtaaaact aataccagca tcttactggg ggtgctaaaa ctagtctcgt agctgctggt
    15121 ccttgaaacc gctataagtg ttaacaagaa aaagaggact atcatatgaa tggcattgaa
    15181 aaaacctgct ttttaatttg gaaaatgatc caattgaccc tcatttttca tctcttgtcc
    15241 ttagctggac tgattgtgtt tggggtgggg ccagcctggc aaaccattgt caccctattt
    15301 ttaaaaacac ctcaagaaga aaaccactat tctttgaaaa gggctgttca actttggaaa
    15361 tcttatttca aagaagctaa tctaagattt ggtctttttg ccctgacttt ccttttttta
    15421 acctttaatt tgcattgggc agtacagttt ccatccttgt tttggtttac cgtgtctttc
    15481 ttgattgtaa tagccatggt ttggctaacc attacctatc tttacatggt tttttatgca
    15541 gtgagctatg agattaacct ttggaataat atgaaattag cctttatcag cgtcttttta
    15601 agtttcaaat cctttttact catgctgagt gttttgctgg gaattacctt agtgacttgg
    15661 caatacaaag gcctttatct ctttttaacc ttcggagctc tagtcttttg cttggacttt
    15721 gtcactaagg ctaatcgtcg actagtagat ggagtgattg atgagtgtta aaacattggg
    15781 aaggtatgtg actaaccact ttaagcaggg ttttttgatt aatcgactga tgaaattata
    15841 tagcctgcta attgtaagtt ttttcacttt agcagctatt ggctttagca gttattctat
    15901 tagtagtact tataaaaggg tggatgctga ggcgcagatg cgactggagg agactctagg
    15961 tagattgcag tcacaaaacg atattaccct acgggtttta gaccagttgg ttggccgttc
    16021 agaagattac cataatctct atcaatacat gacgttaacc ccaaaccaat atttttcaaa
    16081 cgtttttgag gactgggaaa aaggaaaaga cacggtccta ttttctgaag aggtgaggcg
    16141 tctttttgac ttgtaccctg atgtgacttc tatgacccta ctgctagagg acagtagtgc
    16201 ttatctgtac gccgataagg tcattaagac gggtcgtttg ctttatagca agcctgaaaa
    16261 agtaaccgga aatgttttag ttcgctctat tcgaaatcca gaatcaggag atgtgacagg
    16321 tcgtctttac ctgacctttg acaaaccacc gactttggta gagacacagc aggatcacta
    16381 tttagctact tttgcttttg attactatgg ccgcaaactc ttccatcaag gaggtcggag
    16441 atttcctcat ttagaggctg aggttaaaaa ggctatcaag gcagatcggg cagctgatct
    16501 tagtaatctc agcaaggctt atcggatgca gtacaatcgc tcgggagacc tcttagctta
    16561 tgtggctgtc agaaaatcct atttattagc ggaagctgtc aggacagttt ttgtgtatgg
    16621 ccttgtttct ctactcttag cttggctgtt attgcagttg ctctttaggg ttttccgaaa
    16681 ttatatccag caggtttctg aaattacgga tactgttgaa atggttgcag caggcgattt
    16741 gtctttaacc atcgacaaca gccacatgga attggaactg tatcatatct cagaagccat
    16801 taatcagatg ttggccagca ttaaagctta tattgacgaa gtttatgtgt tagaggtaga
    16861 gcaacgagat gcccaaatga gagctctgca gtctcaaatc aaccctcatt ttttatacaa
    16921 cacgttagag tatattcgga tgtacgccct tagttgtcaa caagaagaat tagcagatgt
    16981 catttatgcc tttgcgagtc tgcttcgcaa caatattagc caagataaga tgaccacctt
    17041 aaaagaagaa ctggcttttt gtgaaaagta catttacctt tatcaaatgc ggtatccaga
    17101 tagcttcgct tatcatgtaa aaattgatga gagtattgct gacttagcca ttcctaaatt
    17161 tgtcattcaa cctctcgttg aaaattattt tgtgcatggg attgattata gtcgccatga
    17221 caatgcacta agcatcaagg ctttagatga gacggatcat ctcttgattc aggtgcttga
    17281 taatggacgt ggtattagtc aagagcgctt agcagatatg gaaaaaaggc ttcaagatca
    17341 ccaaacaaca ggcaatagct ctattggttt gcaaaatgtt tacctccgtc tctttcatca
    17401 ttttcgagac agggtttctt ggtccatggc taaggagcca aatggtggct ttatcattca
    17461 aattaggatt agaaaggatg cttgatgtat aaggtactat tagttgacga tgaatacatg
    17521 attttacaag ggctcaccat gattattgat tggcaggcac ttggatttga agtggttcaa
    17581 acagcaagat caggcaagga agccttagcc tatttgactc agtacccagt ggatgtcatg
    17641 atttcagatg ttaccatgcc tggaatgaca ggactggatt taatagaagc agctaaaacc
    17701 tatcatcctc agctacaaac cttgatttta tctggttatc aagaattctc ctatgtgcaa
    17761 aaggctatgg aattagaaac caaggggtat ttgctaaaac ctgtggataa ggcagaatta
    17821 caggctaaaa tgaaacaatt taaagactgg ttggatgccc agcaggcaga atcaatccgg
    17881 caagaagcct atcatgacag ccttttgacc ctttggctta cagatgaatt gagtgagaaa
    17941 gaatttcagc agttaagtca aggcttgcca gcggctgctt taactggttt tacagtgctg
    18001 tatttggact gtcaagagtg gcaagcagcc atcgatgctt attttgaacg agaaggtcag
    18061 cctttttatc tcaaaaaaga agaagataag aaggtttatc tggctgtcct acttggtaaa
    18121 actgatcaag ccaaggcgtt tacctatgat ctacaaaagc gattctcaag aaacatgcat
    18181 caacttattt tgggagaaac agttgatgac tgggaaaatg tttatgaaag ctacaatcag
    18241 gtgcttaaga gcctctttta caattgtgaa gtgtcaccaa ttagagcaaa agataagtcc
    18301 aaaattgaac taccagagtc ccgtttgcag ttctttgctt ttaacaaggc gttgatgatt
    18361 ggggacgaac ctacaatctt gtctaaatta gaagctattt ttgacgagat gaagaccttg
    18421 aacttttcac cagaggatgt gaagcatgtt tcgttcttgt tgttttctga catttaccgt
    18481 caatttccca ttttagataa aatgacttat ctgtccatgg taaaaactat tcatgacagc
    18541 caatccattg atcgcatttt gagggaacta aaaaaagtgt tggatgtcac caatcagaac
    18601 aattcccctg aaaaacgcta ttcagattta gttagtgaaa ccattgattg cattcgcaag
    18661 gaataccatc aagaattaac ccttaaagct atcgctgata ggttacatgt caatggggtt
    18721 tatttagggc aatgctttaa aaatgaaacc gagcgtagtt ttacccagta cttaaatcat
    18781 gttaggattc aaaaagcgca acagttattg ctttatacca accaatccat caatgaaatt
    18841 gcttatgaaa caggttacaa taccaatcat tattttatca agatgtttaa aaagttgaat
    18901 ggtttatcgc caaaagagtt cagagatcgt tacaaggaca attaccaagc catcaagggc
    18961 gaccagtaac gttaaacagg agattgatat gacaccagat agcaaggagc agacagtgac
    19021 tgactaccaa taccactata ttgatcaaga aggaagaaag cagcccttta atcaaggctg
    19081 gcgttttctt atggcagatg tgacgtgtgc tcaggaccct tcttttgatg attcgaactg
    19141 gcaggtgatt catttaccac atgatttcag tcttacgcag ccttacacaa gaaatggtga
    19201 agctgaaagt gcttataaat taggtggtgt cggttggtat cggcattatc tcgtgttaga
    19261 tgaggtttta gctggttgtc atgttgccat tacttttgag ggttcctata tggaaacgga
    19321 aatttatgtt aatgggcaat tcattggcaa acacttaaat ggctatcagg aatttaccta
    19381 tgatatctct gatgtagtga cttttggagc tgaaaatctt ctggctgtcc gggttgaaaa
    19441 caaggttccc agttctcgtt ggtattcagg cagtggtctt tatcgtgaag tgagtttgtc
    19501 tgttcttccc cagcttcatt ttgtggcaga ccaggtagca atgaccttgg ctgatactgc
    19561 tgtgcaggag aaagggcaac agaaagttga tttacgcttt gcccttaatc agtctattca
    19621 gacttgccac taccaattga gcctctgttt atgggaacaa tcacattgct caaaagacaa
    19681 gaaactcctt tatcaagaaa cagaagtgcc tctagctgat ttggctttcc aaagacagta
    19741 tggtcttaca ctgtctttgg aagaactcca attgtggtca ccagataatc ctcacctcta
    19801 cgatttagaa ctcactcttt actatcaagg tcaggtcatt gattgctttt gccttgaaac
    19861 tggttttcgt cagctgactt ttatggccaa tcaggggctt tttgtgaatg gcagagctgt
    19921 caaattaaag ggagtttgtt tgcatcatga ccaaggaggc ctaggagctt gtgcttacga
    19981 agatgcccta gccagacaat tagtcctgtt gaaagacatg ggggctaata ccattcgtag
    20041 cacccataac ccaagtagtc ccaaacttag gcaactagcc aatcgtctcg gcttttttgt
    20101 gattgaagaa gcctttgaca cctggaccta tgccaaaaat ggaaacgtta atgacttttc
    20161 aaactatttc catcagacta tcggaactga aaatgcaaac tatcttcaaa gagtgaggtc
    20221 acctgaaacg agctgggccc agtatagtat tgaggccatg gtctggtctg ccaagaatga
    20281 cccgtcagtg ttgatgtggt cgattggtaa tgaattgatg gaaggttttt cagccgatgt
    20341 cagtcattac ccagagctga caagacaaat gtgccaatgg attgctgcta ttgacacctc
    20401 acgtcccatt acctttgggg acaataaatt aaaagaagct gacttttgct ggcatgagga
    20461 agtgtcgcaa atggcaactc ttcttagtca attagaccat ccccagggac tcattgggtt
    20521 aaactatgct aatggaaaag actatgatag gcttcatgag gaacactctg attggctgtt
    20581 gtatggttct gaaacagtct cagccattac cagcagggct tattataaag agacaaaaaa
    20641 agttcttgac tccggttatc acctaacctc ttatgatcat gctaaggttg attggggtgc
    20701 cttcgctagc caggcttggt atgataccat tacccgtgat tttgttgctg gcgaatgcgt
    20761 ttggacaggc tttgattatt taggagaacc taccccctgg aataagatcg acagcggtgt
    20821 tgtaggcctt tggccttctc ctaaaaatgc ctactttggc attttagaca cggcaggctt
    20881 tccaaaagat agctattatt tttaccaaag tcagtgggcg caggggcaga ccaccttgca
    20941 cctgttacca gtctggcaga aggaccagct ttgtttcgat gagcagggat tggtggaggt
    21001 tgtggtttat agcaatgctg ccagtgtgca actgatgttt gaagatgagc agggcaactt
    21061 aacagattat ggaaggaagg catttcatac ttatagcacg ccaacgggac acacttatca
    21121 gctttaccaa ggagctgacg ctgctaagaa tcctcacgag aatctttacc tgacttggcg
    21181 agtgccctat caaaaagggt tgctaagggc agtggcctac gacatttctg gtaaaagcat
    21241 tccaaaaacc agtggacgtt ctcaggttag aacctatggt tcagtggcaa agctatcttg
    21301 gaaagccttt gaagcaccta ttgacgctcc ttgggaattg ctttatctgg atttatcact
    21361 cttggatagt cgaggtgaat tggtcagcca tgctcaagat tggctaaagg ttcaagtaga
    21421 aggaccagcc cgtttgttgg ctcttgataa tgggaatccg actgaccaca ccccttatca
    21481 ggagcctcta cgccaggcat atgggggaaa attattagcc attttagccc tcactggaga
    21541 ggcgggacac attaaggtca cggcaaaagc ctcgcagcaa cttagcagtg tttttcagac
    21601 acaagtagcc tgccgtgccc ccaaagaaca cttagtgaca ttacctttag agaaatatca
    21661 gtttaaaaag agccgactga caagtcaaca agaaattggt caatcttgtc taaagaccac
    21721 acaattcctt tctgttttgg agaacaaaga cacccagcaa aaagcaggta aggctagcac
    21781 acctcacatt cttatcacca gttaccagca ctatttacct ctgcccttgc aggtttgttc
    21841 tcaggcattt gattttaaaa aaggcgatga tatcttcttg cctcagtggt tccaagtcaa
    21901 agatgcccaa ggttcttttg tgaaaaaagc ttttccaatg acatggtacc taaaagagaa
    21961 aatctttgcc gagcctattc ttgtcacggg ctatgtttct tgttttgggc aatcaatacc
    22021 ggttgaggca aggctcaacc tagcacaagc tagcaaaagg cggcaccagg atctcagttt
    22081 agtcgccaag caatccctgg ccgcaagtca aaaaaggcta acttattgct accaatatga
    22141 tacggtgcaa gccataggag ccattagctt gcaaaatcac acaggcacat ctcttagtgt
    22201 ttctgtggca atcagttatg gtagtcagag ctctattaag caagaaacct tgatgctagc
    22261 tgatagccac ttgagccagt tagaagaggt tattttcttc gatgatattt tgactgtttt
    22321 gtatctggca gtgacccttg aagtcattga aggacctgac ctaactgaag acagtattca
    22381 aattggcctt tgggatttag catgaagcat gagtaaaaga agacttcttt ggcaccaggt
    22441 ctgatgaatt ctgtaaaata aggtataata aaaaacaaat aggcgtcctt tattacgtga
    22501 aaggcgcctt tacaaggttg aaatggaaag tgagatttct aaatgtcaga acgtttatca
    22561 ggccacaccc tgttggtctc tttgcttgct acccctattc gtcatagttt gtctcccaaa
    22621 atgcacaatg aagcctatgc taaacttggg ctggattatg cctaccttgc ttttgaagta
    22681 gggacagagc agttagcaga tgccgtgcaa gggattcgtg ccttaggaat tcgtggctcc
    22741 aatgtgtcta tgccaaataa agaagctatt ttacccttat tggatgactt gtccccagct
    22801 gctgagttgg tcggtgcagt caatacggtt gtcaataagg atggtaaagg acatctcgtg
    22861 gggcatatta cagacggcat aggagcgctc agagccttgg ctgacgaagg agtgtcggta
    22921 aagaacaaaa tcattaccct agcaggagtt ggtggggctg ggaaagctat cgctgtccag
    22981 ctcgcttttg acggcgccaa agaggttcgt ttgtttaacc gacaagctac acgtctaagt
    23041 agcgttcaaa agcttgtgac aaaactgaac cagctaacaa ggactaaagt aacccttcaa
    23101 gacttggaag atcagactgc ctttaaggag gccatcaggg aatctcatct atttattgat
    23161 gctacaagtg taggaatgaa gcctttagaa aatctaagtt tgattaccga ccccgagctc
    23221 attcgcccag acttggtggt ctttgacatc gtgtacagcc cagcagaaac caagttacta
    23281 gcctttgccc gtcaacatgg cgcccaaaaa gtcattaatg ggctagggat ggtgctttat
    23341 caaggagcag aagcttttaa attaatcact ggtcaagaca tgccagttga cgctattaaa
    23401 cctcttttag gtgatgagta acacttttta agtaagctta attatgatat attaataaga
    23461 gatggagcag tcatcatggg ctgctaaaat tctttttgcg agagctgttt ttaagagcaa
    23521 aaagcttatt tgaagagcct tatccctaac gtgatacaag tcatagttcc tgtgaggtct
    23581 gccagataac ctaccgtttt tttagaaaag aagctcttat aaaaggaaaa gttcaatgaa
    23641 taaaggagaa tagcaatggt aacaaaggaa gttgggcatg actttttagc acgtctagga
    23701 aaaaaacgct taagacctgg cggtgttgag gcgacaaact ggttgattga acaaggacaa
    23761 ttctctcagg attgtcacgt tttagaggtt gcctgcaatc gctgcacgac agcaatagag
    23821 ttagccaaaa ccttcggttg tcagattgat gccgttgact taaaccccaa ggttgtcaaa
    23881 gaagcacaag aaagggttgc tgttgagggg ttaacccgtc acattacagt atcccaagcc
    23941 aatgctttat cactaccatt tccagataac cattttgata ttgtgattaa tgaagccatg
    24001 ttaaccatgt tgaacgccca agccaaggag aaggcactca atgaatattg gcgtgtgtta
    24061 aaaccaggcg ggcgactttt gacacatgac gtagcttatg aagatccaaa aacaagacaa
    24121 gtacttgacg agttacgtca aacgattcat gtcaatgttg ctcccttgtc actaacaggt
    24181 tggcaagcct tatatcaaga acacggtttt tctcaagtga cttatcacca tgggaaaatg
    24241 tctttgatga cacctcgtgg aatgattaag gatgaaggtc ttatgaacac cctgaacatt
    24301 atgagacgag gccttaagaa agagaacaga caacagtttt taaagatgcg tcgttttttt
    24361 accagaacag gcaaaaatct ctgctatatt gctgtaaaaa gtgtaaaata aaccttagac
    24421 caacctgtcc atacaactaa acagaccata gaggagttcg aagatgtctt atatcaataa
    24481 tattgagcac gcgaaggttc ttgatttgac gcaagaagta atgattgagc aagatcaaat
    24541 gttaagtaga acactagtcc aaaggcaaga cctaggaata acagtttttt ccttagataa
    24601 gggccaagaa attgggcgac actcatcacc aggagatgcc atggttacta tcttaagtgg
    24661 cttagcagaa atcaccattg atcaagagac ctaccgggtt gctgaaggtc aaaccattgt
    24721 gatgccagct gggattcctc atgccttata tgcagtagaa gcctttcaaa tgcttttagt
    24781 agtagtaaaa ccggaggttt aacatgattg aaaatctctc tcaactggtg caatatcatg
    24841 atcatcaggt ggctagccga tccttgagcc gtctactggg attatctcaa tctattgttt
    24901 tatatgccat ggcccaagga gaaagcatta gtcaagagac tagtccaaaa gataaagtaa
    24961 tacttgtttt agaaggtcag ctcattttcg atttagagga tcaaaaacag gtcctaactc
    25021 aagaaagtct catagccata cctgcccaaa aagtccatca tttagaagct aaaaccgatt
    25081 gtaaactatt acaagtgctt ttagattaag ggcttattgt caactgtatt gggtggccta
    25141 tggaaaagca aaagagaaga tgacaatacg aattttaagg cttggctttc tcatctccag
    25201 attaagccct ttagcttggt ttagtttaga attcactaaa aaaaccttaa tgagtttcct
    25261 atctccttat aggtttctca ttaaggcttt ttagacgaaa taattgaacg acaggcaaaa
    25321 gaaagatctt tttacgagtg ataccgttct cctatagttt cataaatcct ctttttgatg
    25381 ttgctgttag ttattcttag ctaaaagtta tattgttatc aagacttgtc ttgtagtaac
    25441 atgttttagg agttccagga taccgttatt ctcttagcaa gcttaactag ctagagtgga
    25501 gtcactattt ataataaact gtcgagcttc tcgacaaatt ggtgatcgtc tttgttaatg
    25561 gctagggtgg taaaaccggt ttctgtgggt aatataaaga taatatgttg ctcagaattc
    25621 ttcttatctg ttttaaagac gtcaaagagg gatgtcgcag agacatcagc tctttcaagt
    25681 gttgttggta actggtaacg ttcaaaaact tgaaggaggc tatccaagtc ctcttttggc
    25741 aagagtcctt tggaaacagc cagtttagca tcaaccacca taccgatagc aatggcttca
    25801 ccgtgatggt aaaaatcatg gtggcagagc gattcaatcg cgtggcccaa ggtatgccca
    25861 aaatttaaag acatgcgcaa accattttca aattcatctt gttcaacaat atgtttttta
    25921 ttggaaatgg attggtaaat cagacgttca agtccctgct tatcggtttc tttttgaaaa
    25981 tcacgtaact gctgaaaaag cggtctatca tgaatgaagc cgattttgag catctcactg
    26041 atgccgcagg agaattcccg ttgcggtaag gtttccaaaa aggtggttga aataatgata
    26101 gcttctggag ggtaaatgct gccaatcata ttggttagac ttttaaaatg gactccaact
    26161 ttgcccccga tactgctatc cacctgacta agtaaagtcg ttgggatttg aatgtaggga
    26221 ataccacggt aataggttgc agcgacaaaa ccacccagat ccccaacaac accaccacca
    26281 atagtaacaa tcatatcttt tttggaaaaa ttttcagcga tgagctggtc gtagatagca
    26341 ctgacacgtt ccaaggattt ggtttgacct cccggggggc agacatggac aaaagcgttg
    26401 tattgctgag caaattcttc aaagagagtc tgatacaagt ggtagaccgt ttgatcggtg
    26461 ataaacaaga gtttacgctg cttgcgctca ccaaggcaat ctgctaaggt ttttaaaaca
    26521 tggtcggtaa acaggatatc ataatccttg acccgagaat ggacatgaag tgtttgtggc
    26581 ataagcactc ctttcatcag tactaggtaa cagagataac gcagtgatat ttagagctta
    26641 atcttgccaa agttcctgcc ccaactgttc taattgctta taatcaattt gctgggcagc
    26701 atctgacagc gcatggtcgg gatcaggatg aacctccatc atgatgccat tggcaccgac
    26761 agccttcgct atcttagcag caggtaagag taaatctcgt ctgcctgtcg aatgagacac
    26821 gtccacaata atcggtaaat ctgtcttttg ttgaataata gggactgcca taatatcaag
    26881 catatttcta gtctccacat cgtagccacg aacgccacgt tcgcataaga taatgttaga
    26941 ttttccagtg tcttgtaagt aggaaagggc gcccaaatat tcctcgatag tagccatcaa
    27001 gcctcgttta aacaaaatag gcttatcgat gtgtgacaag gtttttaaaa attcaaaatt
    27061 ttgcatgttg cgggcaccaa cctgaatgac atcgagatag tcataggctt cttctaattg
    27121 gcgctcggac atgatttcac tgaccgatag taagccaaat tcctgacaaa cctcatgcaa
    27181 gtaacgaatt ccttgcagac caaggccttg aaaagaagca gcagatgttc ttggtttata
    27241 ggcgcctcct ctaaaatagt tataaccaag ttttttggca cttgaagctg ctaatctaat
    27301 gtgatcataa gattcaatgg aacaaggtcc aacaataaaa ttattcttag aacaagtctt
    27361 attttgaaag tcagacataa tgtcaatcat tcgtttgatt cctttactaa ttctgtatgg
    27421 cgtgctctat gggataacgt cttatttagg aatacaaaat ctcgttgtta tccatgaagc
    27481 acccttagcc tgtgaaatga taccataaac aagatgaaat agcaagtaaa ccctagattg
    27541 tctatgttct tagtcatttt tattaaaaaa ggcttgttag ctataaaaaa tactgcccta
    27601 aatcttatta gggcagtatt ttttatagat gccaccaccg agaatcgaac tcggaacgaa
    27661 gcattaccat tgctttatta taccatttaa ctacagcggc taccttttta taatactata
    27721 agttattaat tgatgcaagc ttttcttaaa aatatttcct taattgttta tcatcaaaat
    27781 gagagtacca gtta
//
LOCUS       DAUGOH010000021        25472 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUGOH010000021 DAUGOH010000000
VERSION     DAUGOH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25472
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.021"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            22..822
                     /locus_tag="VH957_001019"
     CDS             22..822
                     /locus_tag="VH957_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEQ8558937.1"
                     /translation="MSKANRRIWQGLAVILIAIITTFTTSTATAAKKIRNFPTTTEIL
                     SGTKATEAPGILPFTGSYKLVLGDLDNLRRPTFAHIQLKDQDEPKIQRKGLKFNPPGW
                     HNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDRNPLGMLYY
                     ENRLDSWLALHPNFWLDYKVTPIYHENELVPRQVILQYVGIDEDGNLLQIKLGGEKES
                     VDNYGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNVETEEFEEAA"
     gene            complement(884..1084)
                     /locus_tag="VH957_001020"
     CDS             complement(884..1084)
                     /locus_tag="VH957_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8558938.1"
                     /translation="MSEEKLKAKVEQASGSLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(1269..2240)
                     /locus_tag="VH957_001021"
     CDS             complement(1269..2240)
                     /locus_tag="VH957_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEQ8558939.1"
                     /translation="MKQPLALTWEDQIRLFEKRGLIVKADDVEKIKHISYYRIKEFAK
                     PLEIKRQDGEEKDILYDNIEFAEVLARYYQDKNLRIYLLHAIEKIEVSIKTKISFVLG
                     DRYGAFGYLNFSSWANRNKFTKYDIEKRQFRIKKNLLNTVRKSQLTELQKSINLDPDG
                     FPTVWLAIDLLMFGDIVSILTIMSEKNIKQICQYYSCTPEELVSWLKCLNFIRNVCAH
                     NSNVLDIQITTKPKLRSEWRNYIDTVKIKHNVTKPSNKLSVIIAIVVYLVNTINSKYQ
                     WRKIQSSLKALCKEDDSRAKLLGFKDYDSVKAMINGIKCTAFTNSKK"
     gene            complement(2534..3751)
                     /locus_tag="VH957_001022"
     CDS             complement(2534..3751)
                     /locus_tag="VH957_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8558940.1"
                     /translation="MTVDTEKAIAWMGLKEGRVSYSMDYRNGPDSYDCSSSVCSALIY
                     AGASNPGWLLNTEYMHDWLIQNGYQLIAENADWASLRGDVFIWGMRGQSAGAGGHTGI
                     FIDPDNIIHCNYARNNITIDNYNQTAVASGWMYSYAYRYVGGTDKCVGSKSIDELAQE
                     VLSGKHGSGEQRKISLGANYDAVQAKVNEMLKQPKVAEQSPAVKQDGDLMFNGAVLKK
                     SILDKILVKCKEHDILPSYAITVLHFEGLWGQSAVGRSDNNWGGMTWTGQGNRPSGIT
                     VTQGTARPVAEGGHYMHYESVDDFLTDWFYLLRAGGSYKVSGAKTFSEAVKGMFIVGG
                     AKYDYAASGYDNYIVGMSSRLKAIEQENGPINKYDQQADISAEQSDKIDVVIDSLEIT
                     INGVTYTATKKPI"
     gene            complement(3867..4094)
                     /locus_tag="VH957_001023"
     CDS             complement(3867..4094)
                     /locus_tag="VH957_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEQ8558941.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKK"
     gene            complement(4091..4366)
                     /locus_tag="VH957_001024"
     CDS             complement(4091..4366)
                     /locus_tag="VH957_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558942.1"
                     /translation="MATELIFGVGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHAEQNKTLITMTEQIKNLTDDVKDLKDMMRGEIK"
     gene            complement(4376..4993)
                     /locus_tag="VH957_001025"
     CDS             complement(4376..4993)
                     /locus_tag="VH957_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8558943.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQDLNS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHMLTSGGKIDSDIYKGMLELIEPAQKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEAFEYDKQTLEELESEAKVTVIKYADLVKQD"
     gene            complement(4996..5427)
                     /locus_tag="VH957_001026"
     CDS             complement(4996..5427)
                     /locus_tag="VH957_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ8558944.1"
                     /translation="MDLTIKNKELNTLYSVLDKIKITNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPTKLDEFSGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGE"
     gene            complement(5436..7325)
                     /locus_tag="VH957_001027"
     CDS             complement(5436..7325)
                     /locus_tag="VH957_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8558945.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFTADGDTKSVKIANNRCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGTGNPTGLFKDLKEISLELTDTKNSKLWSKIKL
                     NNQGMIEEYYNGTIKSEIIKTAEGTQQRISSETDKKLALINETVSGIRREYQDADRQL
                     SSSYQAGIEGLKATMANDKIGLQAEIQTTARGLSQKYDNELRQLSAKITTTSSGTTEA
                     YENKLNGLRAEFTRSNQGTRTELESQISGLRAVQQTTASQISQEIRDRAGAVSRVQQD
                     LDSYQRRLQSAEGNYNSLRETVAGYERRISNQDNTISSNFTQLKTLIDQSVTLEKVQS
                     LLRQSGDSIMLAIKDKLPKSKMSGNEIISAINLNSHGVQIAGKNITLDGNTTVNGAFT
                     TKIANAIKIKADQIIAGVIDAAKIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYAEGYQHTAAVDQTEIYGDSVLVVDDFN
                     ITRGFKFRPDKMAKMLDMNDLYAAVVALSRCWRHLSNVGWNPSHRNFINAVNSELNNY
                     VQKII"
     gene            complement(7336..7665)
                     /locus_tag="VH957_001028"
     CDS             complement(7336..7665)
                     /locus_tag="VH957_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558946.1"
                     /translation="MRGHNLLKDLNNIIINNKTIDRIICNNTIVYQRSWNLLFDGLLT
                     SAGKKLDIYPFYKIVINNAFFVKTPTTKNNTIFLAGHKILALQDSHFCFFRALEKSFF
                     VKIYGKN"
     gene            complement(7652..8875)
                     /locus_tag="VH957_001029"
     CDS             complement(7652..8875)
                     /locus_tag="VH957_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558947.1"
                     /translation="MTLEERIPIKVLFDRKDAAEWQKLNPVVDDGELVVELDTHRLKV
                     GDGKLTYNDLPYYEGPQGESITKVQLSENGDLSVWIGEKETKLGNIKGQKGDKGTSIT
                     DITKDGETLTIKLSDDTQKTFNIPNGQKGDRGKSVESARVDESGHLKLKIEEESELDL
                     GNVKGESGPKGDSITITGQQRVSEGVQLTFSDKTKVVIPKGEKGDTGDVNGINLEDYV
                     KKSELKNVGSADVKAINDFLGLSQKVFTSSYSYTDSLLKSYAKPSYSASWYVNESTVS
                     TKNGDKVLITIHNTTTQADNYLEVAVTYVGANYVTATSTGRLLTTPGEVKVVTKKQAK
                     EDYAAKKHKHEISDIAGLNERLSGYLRQADIQSQLNNIGKLKDTQTGQYLEVKVVDKG
                     QVPSNTSGMIVFERS"
     gene            complement(8872..10983)
                     /locus_tag="VH957_001030"
     CDS             complement(8872..10983)
                     /locus_tag="VH957_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8558948.1"
                     /translation="MIYLFDRDEKLIKIIRKNACKSVIQKQTLTDTNYVSDLLTAELK
                     ALPDDILEQSEYMAVPTKEDKRKFHLFFIVRDETEGNATVLSGVQSGIEELRKAVAEN
                     KRPRKRDAREVIKYLLKDTNWHARYVAETGKSSTNFYYDSVFDSLLKVCSAWQLEMQF
                     FVEMNNNEIGARYIDFKKKIGVAEGRRVVYGHNALKILKQNEKAELITAVIGRGNGQE
                     VSSAEENEGGKAGYGRKITFKDVVWTKPNNPLDKPAGQLYLELPEATEEYGINIKGKK
                     VPKIGVVDIDSDDPEELLQRSYEYLVDHARPRAVFKTTSAYLKANIGDTVRVVRKDRN
                     LDYEVRVFEITWDRLSNKAIDIKLGDRLNASDSLKKAQLQSHLTDSVSDTVFDTLGQF
                     LKDELPSAGGFNTNFYSENEPDKSKVKIGDIWFKPDPEHEGHKIMLIWDGKNWVEVVR
                     SYNSDIAKTAVEEAIKEIEKLKQHQQELDERNQKELDEFRATLKNLALPEEAIKKITE
                     TIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEILGNNGKTHYNKNLLVGDPNRVKTY
                     DQDYIELEANDGGFKRGETYTISFSQTCELLKKVAITLTQINNKGVKLVLTPTKAKMD
                     AQTFEVAKDKQSIEVYPLSYTAVLTGDWYKSKQIDLNASEVQELALDMSYKEIADAKG
                     ATIIGKQSDKPKIILDGRRDR"
     gene            complement(10980..11750)
                     /locus_tag="VH957_001031"
     CDS             complement(10980..11750)
                     /locus_tag="VH957_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEQ8558949.1"
                     /translation="MYDYVNLKGGASVTARLPSDNMSVNGKPLNELIPGYRQLHVSGR
                     GIVSQEIETIAIPSRRGVYISNIQDKEREITVTFQLTSDNSEGLREAFAKLNKNLRGE
                     LSLTFADEKDFTYKGFLKSAPDDSEQSLTLVSSFTLLIPDPYKKGALKTSRGPITLTH
                     ADKVLPNKIVLQSTGGAEIEITAGSERMKLKGHYGSGDKITIEWLDDEVVIKHNNNLA
                     LSNLLHLSVPEEFYVKNGDTIQATNAAVESVEWRDEQL"
     gene            complement(11750..14749)
                     /locus_tag="VH957_001032"
     CDS             complement(11750..14749)
                     /locus_tag="VH957_001032"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEQ8558950.1"
                     /translation="MAGVADFTLTALIKADASGFRAGVQDAKNALNELQKTTGSRLQR
                     IGDTFGGVGKALTAGLTLPLTALGGASLKAFSDYDTALIGVRKTTDISGDALNRFSKQ
                     IMSLSREMPNSAVEIANLAEVAGQLGIRTDEGGKHLINFSRIAAQMGTATNMSSEQAA
                     NAMARLANITQMPQTQFHRLGSTIVALGNKMATTESEISEMALRLAGTGHQVGLTEAQ
                     IAGLAAGMSSVGINAEAGGSAFSRVMQKMNTDVLSGGEGLQKFASVAGKTAEEFAQTW
                     RKNPQEAIVDFVKGLGKIKESGGDVTETLKDLGINSVREIDTLARLSGAGDLLAKSFN
                     IANKAWADGTALQKEADAASQSFANQLKLLKNALFEAGTVIGKHLAPRIGKLAEGIKK
                     ITQAFSDLDPKVQDGIISFGIFLATIGPVFLVINKIITGIRMLATAFGFIKGLVTAFK
                     TAGTALTGFKAVIAALGGPITLIIAGIMALVGVLTYLWTTNEGFRNAVTGIWEAVKQV
                     FSTAWEYIKNAWAAAPSFFSNLWETIKNGASSIWDNVKTVWASVVDFLKAVWQGLADF
                     FSPLWEGIKSSALGVWESFVTGMIPIVDAFKNLWSSLTEFFTALGEQIKPIWEDIKQF
                     FTDTWNIIVTIFQSALAILTPVVQAGFEIIKLQITLVWEFIKTYIQLAWVIISNTVQV
                     ALTTLAAIITAGFEIIKTVIQTMWEVIKILVQSAWTVITTIVSTAINVVAEIIRTVTA
                     VIQGDWQAAWEAIKSIFEVAWNAIKTIGETLFNALKSVIETILNALKSIWDSVWNAVK
                     ATAESVWNAIKAIVSGAMDAMKNAVSNGINAVKNFIVNGWNSVVGFLSSINLFSAGSA
                     IMQSFLSGLKSMWGAITSFVGGIASWIKSHKGPISYDRRLLIPAGKAIMSGLNNGLSN
                     GFGQVKNNVSGMADSISKLVDGNSLFDADMSSTISGAVATGVEVDLGHQAKPLELNLE
                     LGNRAYGLFVDDITDRQRATARLTEVY"
     gene            complement(14759..15067)
                     /locus_tag="VH957_001033"
     CDS             complement(14759..15067)
                     /locus_tag="VH957_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558951.1"
                     /translation="MAIAMARFGLSLLEAKRLTWHDYCIYDLAHQVKMQEEETMLAKQ
                     AWFNQAVKATKGTGKNVRSAYKSFKDFYDAGKAFDAIFDTKPKKPKLSIADLNRVINE
                     "
     gene            complement(15088..15456)
                     /locus_tag="VH957_001034"
     CDS             complement(15088..15456)
                     /locus_tag="VH957_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558952.1"
                     /translation="MEITVGKKTYDLVFGFDFLKYANKHRAIEMDGVGIGAGSMTKIE
                     AGSAFKDPEVLLFILKCATSTEKTKPSNEELEKFIEEAIVNGTYIGFYDEVVAEIKKD
                     AVLQQAIAGNQVIEAVTKAK"
     gene            complement(15469..16029)
                     /locus_tag="VH957_001035"
     CDS             complement(15469..16029)
                     /locus_tag="VH957_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8558953.1"
                     /translation="MAELIQGKSFLLFFRRLDDVETKDAAKLRFQTEHSIKMEKETEA
                     TKTKDGIINSLSDGENTIDIKSFAYTSDESTTAIWEELRKYFKDGDVVEIWQVDLTSK
                     DSGHQKYKAEYFQGYFTSFEISAPADGQVELSMTYAINGNGVEGVDELTSEQKQAVSD
                     VLYRYKSMARGGAEPEETKKENSFEM"
     gene            complement(16030..16416)
                     /locus_tag="VH957_001036"
     CDS             complement(16030..16416)
                     /locus_tag="VH957_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558954.1"
                     /translation="MTPNNAVFRQIFKECLAVTKNTYDYLPNANAKYPFAYIGESSNT
                     PSNNSEMMGVIRQTIHVYGELKKRSEIDNVVTNLHDKIISLTSAYGYNFRVDRINEQT
                     LPDNSDTTPLLHTVLDVYLTYTKKGN"
     gene            complement(16413..16769)
                     /locus_tag="VH957_001037"
     CDS             complement(16413..16769)
                     /locus_tag="VH957_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ8558955.1"
                     /translation="MPSVTIEWKGIEKAFSKLVNASGNIDRLTDAVVKNHAEKAKAEA
                     QRIAPYDTGFLHDEIYTHYPAKASAEIVSNAGYSGFLEYGTRKMPAQPFLRPAIESIL
                     PDLEKDYNSVIRRAFK"
     gene            complement(16769..17065)
                     /locus_tag="VH957_001038"
     CDS             complement(16769..17065)
                     /locus_tag="VH957_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558956.1"
                     /translation="MRYADRVTFVKTTDEQYDPDLGEYTHTETISETKPCFAMEMGAE
                     KSVQIFGDYQKDRKVIYLKQPYTKAFDYCEYEGRRYKAQANKLGAIVFYLEEVL"
     gene            complement(17062..17415)
                     /locus_tag="VH957_001039"
     CDS             complement(17062..17415)
                     /locus_tag="VH957_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ8558957.1"
                     /translation="MQEINTDSIIANVKLDLGILDSQQDDLLNMLLKRVTDHFKAKYG
                     VVKIDSAFSFVLEDCLIARFNRRGAERAKSESVEGHTTTYYDFLDEFEPYDNMIMAKL
                     DLIKDKSRKGGLYFL"
     gene            complement(17429..17671)
                     /locus_tag="VH957_001040"
     CDS             complement(17429..17671)
                     /locus_tag="VH957_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558958.1"
                     /translation="MPRVIRAFKDKVTKVVYEVGDIYSGDRVEFLTEGGVLEPSVDFD
                     KLKVSEIKSKLDELSIEYDAKLKKSELLELLKQTIG"
     gene            complement(17681..18754)
                     /locus_tag="VH957_001041"
     CDS             complement(17681..18754)
                     /locus_tag="VH957_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEQ8558959.1"
                     /translation="MAYIHEIITSENIKGFYDKQKGEAELTLGEKAFPSKQQLGLKLS
                     FIKGAAGRPVTLKAAAFDTKVPLRDRMSVELIDEEMPFFKEAMLVKEADRQQLNMLAQ
                     TKNQELIDTILASIFNDKVTLISAAKARIEAMRMEVLSSGKIHIASNGVMKDIDYGMT
                     EEQTTKAKNKWSDANQATPLADITTAIEAMAERGYAPEAIIMNSKTFSLIKNADNTVE
                     VVKPMAPQGSAVTKNDLNTYLEDELQVKVILKDGMFVGDDGKARKYFPDGVATLVPNG
                     SLGSTVFGTTPEQSDLMGGQATDAEVSIVENGIAVTTTKTTDPVNVQTKVSMIVLPSF
                     ERLAEVQIINANGETKKENSFEM"
     gene            complement(18754..19134)
                     /locus_tag="VH957_001042"
     CDS             complement(18754..19134)
                     /locus_tag="VH957_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEQ8558960.1"
                     /translation="MNKRKVTTSKEILHNLPYEAISVTLDSSELDEKIIKAGAVLAGK
                     EKSVFEDRTQKVKEVKNGEISSENNICGILLTDVDLTNGDAVGSCVYRGTINADKLAD
                     PSIAENYKDLKEKLPHIQFIEGGK"
     gene            complement(19144..19677)
                     /locus_tag="VH957_001043"
     CDS             complement(19144..19677)
                     /locus_tag="VH957_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8558961.1"
                     /translation="MAEETQTVETVEEQVVPEAKQPQDEKKYTDADVDAIIDKKFAKW
                     KSEQEAEKSEAKKMAKMNEKEKADYEKQKLLDELQELKNDKTRNELTAVARQMFAESE
                     INVNDDVLGLVVTLDAEQTKANVTTLANAFAKVIADDRKALVRQTTPSTGGGLSKQTN
                     YGANLASKAAQQSTKLF"
     gene            complement(19907..20176)
                     /locus_tag="VH957_001044"
     CDS             complement(19907..20176)
                     /locus_tag="VH957_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558962.1"
                     /translation="MNKRIKKKRKLEQVIVLLIAENAMQAEAIKNQNRQIAELRAIIQ
                     QNVQATNNELAAVKGVCFDNQAAITNIAIDVNYIKKNYKRKWGKK"
     gene            complement(20169..20348)
                     /locus_tag="VH957_001045"
     CDS             complement(20169..20348)
                     /locus_tag="VH957_001045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558963.1"
                     /translation="MNKISLNIEMTWENKDEFQQIMNKVNETKEAYKKALEAAGNFVP
                     EMSCATKLNKGEGNE"
     gene            complement(20363..21283)
                     /locus_tag="VH957_001046"
     CDS             complement(20363..21283)
                     /locus_tag="VH957_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ8558964.1"
                     /translation="MKSTQKQRNEAYNRERKAMDAWVKADLENEAMLKQLYTQSKAQI
                     EANIDRFYMRYADKHGLDKRTVKKLADSFDVTAYQNMAKEAVANRDFSKEANLWLSVY
                     NLKMKVSREELLRAELNYELLKMHTKIDNQIQLAREKIALDEMKRQAGILGGQGSVAK
                     RLKGILNADFYGKNFSERVWGNNGLYHETQKSLFSSLSRIATDMQGYKKEKERLMRRF
                     DVAEHEALRLLKTESARIRSDVQLDAYKKNGFTHYIFVCEPGACQICTPYDKERFELS
                     KGATAITMPPLHPNCRCSTYGEVDYGSVIK"
     gene            complement(21255..22757)
                     /locus_tag="VH957_001047"
     CDS             complement(21255..22757)
                     /locus_tag="VH957_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8558965.1"
                     /translation="MYTESFRDSTGKTKTLEFRFHREARMRYQAESLESLLTEKYKLL
                     REMIEHHDKVQKPRIQELLDYAEGNNHTISEMGRRKDDDMADVRAVHNYGKYISTLKQ
                     GYLVGNPIRVEYIDGTEQQQDLLKDLSVKNNFHQLNRRLVKDLSKVGRAFELIYRSMD
                     DKTEVVRLDPREVFVIYQNNLEQSSLAGVRYYNKNQLDGTTKIVELYTDNKILKFEYD
                     GDLTPIGEASSHAFGSVPITEYLNTDDGMGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPGYVDTAEKAIEYLRKMRKARLLNLEPPVDQDGREGSVDAKYLYKQY
                     DVQGTEAYKNRIVSDIHKFTNTPDMTDTKFAGQQSGEALKWKVFGLDQERVDMQALFE
                     QSLKRRYKLIARVSQLLKEIDDFDISKLKITFTPNLPKSLQEKIEAFKALGGELSQGT
                     IMAITDIVEDARKEFENIQSERREEESNNPSLSDFDLGVLRREINTETTK"
     gene            complement(22769..24076)
                     /locus_tag="VH957_001048"
     CDS             complement(22769..24076)
                     /locus_tag="VH957_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8558966.1"
                     /translation="MKTTYQTKPKLEIKVDLPKTIGIGYGAFWRSKNFYRVVKGSRGS
                     KKSKTTALNFIVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNQLKVTHLFKFNES
                     LPEITVKATGQKILFRGLDDELKITSITVDAGALCWAWFEEAYQIETEDKFSTVVESI
                     RGTLDVPDFFKQITVTFNPWSERHWLKRVFFDEETKRDDTFSDTTTFRVNEWLDEVDR
                     KRYLDLYKTNPRRARIVCDGEWGVAEGLVFDNFEVIDFDIDKIVSKHDTSSGMDFGFT
                     QDPTTLICVAVDLESKELWLYNEHYQKAMLTDDIVKMIRDKNMHKSYIAADSAEKRLI
                     AEIRSKGISGIVPSLKGKGSIMQGIQFIQGFKIHIHPSCEHTIEEFNTYTFKQDKEGN
                     WLNEPIDKNNHIVDAIRYALEKYHIARKQSTNTFNILRQGLKY"
     gene            complement(24054..24536)
                     /locus_tag="VH957_001049"
     CDS             complement(24054..24536)
                     /locus_tag="VH957_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEQ8558967.1"
                     /translation="MDWRWWKIAYEELTEKQQRFVDKYITTFNATESAKQAGYSEKSA
                     YSQGQRLLKNVEIQKAMKERFLEAKDTKGDRIQDVAETLEQDTSIARGEIQISEFKET
                     DMLTGQVVIHTKREYTPSHEEQGRARDRIYKVNGAYSEKRELEHSGTVVFVNEDDIPD
                     "
     gene            24596..24853
                     /locus_tag="VH957_001050"
     CDS             24596..24853
                     /locus_tag="VH957_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558968.1"
                     /translation="MLSLLPTPFWDTSIYRTGTVGIEPTHLLLALRKEFSDLAIVPKQ
                     GATLTVFQSRFMFQRFRRAKTSHKRSSTDLARIERATALNI"
BASE COUNT         6748 a         5622 c         4420 g         8682 t
ORIGIN      
        1 taattaaagg aggacatgga tatgtctaaa gcaaatcgtc gtatttggca aggtttagct
       61 gtcattttaa tagctataat aaccactttc acaacaagta ctgccacggc agccaaaaaa
      121 attagaaatt tccctactac cacggagatt ttgtcaggaa cgaaggcgac tgaagcacct
      181 ggaatcttgc catttactgg tagctacaaa ttagttttgg gtgaccttga taatctgcga
      241 agaccaacct tcgcacacat acagcttaaa gatcaggatg agcctaaaat tcagcgaaaa
      301 ggacttaaat tcaatcctcc aggctggcat aactacaagc tgactgatgc taatgggaaa
      361 acaacttggt taatggatcg cggccatctg gttggctacc aatttagtgg tttaaatgac
      421 gaacctaaaa atctagttac aatgacaaaa taccttaata ccggttttag tgacagaaat
      481 cctttaggaa tgctctatta cgaaaacaga ttagacagtt ggttagcttt acatcctaac
      541 ttctggctag actataaagt tactcccatt tatcatgaaa atgagttagt ccctcgccaa
      601 gtaattctac aatatgttgg aattgatgaa gatggaaatc tacttcaaat taagttaggt
      661 ggtgaaaaag aaagtgtaga taactacggc gtaacatcag ttacactaga caacgtatct
      721 cctttagctg aattggatta ccaaacagga atgatgctag attcaactca aaacgaagaa
      781 gatagtaacg tagaaaccga agagtttgaa gaagccgctt aacataaatt gactgcacta
      841 taaaaaacaa ccgcccagaa attaatctga gtggttggtt tttttatttc agtttttctt
      901 tgacagcatc tactgcccct tcaactgctt ctttagcatc atctgctagt tctttacctt
      961 tggcaattgt tttttcaaca aatccttttg cctctaactc tttatcacca gttagctttc
     1021 ctgcaccttc tttaaggcta cctgatgctt gttcaacttt tgcttttagt ttttcttctg
     1081 acataatatg cctcctttat tttattctat ggtaacactt tgagcatcta taagcaaaca
     1141 aaaaacccag ccgcatggac tggggaaaat tagcttttat gaaagcttta ggattatgaa
     1201 tatatactaa cacacaacaa ataaaaaagc aagagccgct agtgtcaggc gattcttgct
     1261 aaaaatttct atttttttga atttgtaaaa gcagtgcact ttattccatt aatcattgcc
     1321 ttaacagaat cataatcttt aaaacctaaa agctttgccc tactgtcatc ttctttacaa
     1381 agagccttca aactagactg tatttttctc cattgatatt tggagttaat agtatttaca
     1441 agatagacta caatagcaat aataacggat aacttattag aaggtttagt cacgttatgt
     1501 ttaattttta ctgtatcaat ataatttctc cattctgaac gaagtttagg ctttgttgtg
     1561 atttgaatat ccagtacatt tgaattatga gcacatacat ttcttatgaa attcaaacat
     1621 ttaagccacg aaacaagttc ttctggtgta caactgtaat attgacaaat ctgtttaata
     1681 ttcttctcgc tcatgattgt taagattgaa acgatgtcac caaacatcaa taaatcaata
     1741 gcaagccaca ctgttgggaa tccatctgga tcaaggttaa ttgatttttg taactcagtt
     1801 agttgagatt ttcttacagt attcaataaa ttctttttaa tcctaaattg tcttttttca
     1861 atatcatatt ttgtaaactt attcctatta gcccatgaag agaaatttaa atatccaaat
     1921 gctccgtatc tatcccccaa aacaaaagaa atttttgttt taatagacac ttcaattttt
     1981 tcaatagcgt gcagtagata gattcttaag tttttatcct gataatatct tgccaaaact
     2041 tctgcaaact caatattatc atataaaata tctttctcct caccatcttg tcgctttatt
     2101 tcaagtggtt ttgcaaattc tttaattcta taataactga tgtgtttgat tttctctaca
     2161 tcatcagctt taacaattaa tccacgtttt tcaaataacc taatttgatc ttcccatgtc
     2221 aaagctaaag gttgtttcat aactctccta acgatataaa aaaagcccca tatcagaacg
     2281 tatctgcctt taaaggaatg gggggtttgt cttgttaaga taattatact ttttttaaaa
     2341 ataatgtcaa gacacaagat cgtgtcttga aacttataaa ttcaagcgaa cacaacatat
     2401 tgaataattg tatataaaaa tacattttta acacaatata ttgtaaaaat tttgttgcat
     2461 tcactattaa taccaaaaaa cagcccagaa attaatctga gcggttttgt cttatcttaa
     2521 ggagctttac ctcctatatt ggttttttag ttgcggtgta ggtaacacca ttaatagtaa
     2581 tctcaaggct gtcaataacc acatcaatct tgtcagactg ctcggcactg atgtcggcct
     2641 gttggtcata cttgttaatt ggtccatttt cctgctcgat tgcttttaat ctgctagaca
     2701 tgcctacaat ataattatca taaccactag ctgcatagtc atatttagcg ccaccaacga
     2761 taaacatgcc ctttacagcc tcactaaaag tcttagctcc tgaaaccttg taagagccac
     2821 cagctcttaa cagatagaac caatctgtca aaaagtcatc aacactttcg tagtgcatgt
     2881 agtggccgcc ctcagcaact ggtcgagccg tgccttgggt aaccgttata ccgcttggac
     2941 gattaccttg gccagtccat gtcatgcctc cccagttatt atcagagcga cctactgcag
     3001 attgacccca aagcccctca aaatgcaaca cagtaatggc ataacttggc aagatgtcat
     3061 gctctttaca cttaactagg attttatcta agatagactt tttaagcaca gcaccattaa
     3121 acattaagtc tccgtcttgt ttgacagcag ggctttgctc ggctactttt ggctgtttga
     3181 gcatctcgtt gacttttgct tgcacggcat catagttagc accaagtgag attttgcgct
     3241 gctcgccact accatgtttg ccagatagga cctcttgagc tagctcatca atgcttttgc
     3301 taccgacaca tttgtcggta cctccgacgt aacgataagc gtaagagtac atccaaccgc
     3361 tggctacagc tgtctgatta taattgtcga ttgtaatgtt attgcgagcg taattacaat
     3421 ggataatgtt atctggatca ataaaaatac ccgtgtgacc accagcgcca gccgattgac
     3481 cgcgcattcc ccaaataaaa acatcaccac gtaggctagc ccaatccgca ttctcggcaa
     3541 tcaactgata accgttttga attagccaat catgcatgta ctctgtattg agtaaccaac
     3601 caggattact agcgccagcg taaatcaatg cgctacaaac agagctagag cagtcatagc
     3661 tatcggggcc attgcgataa tccatagaat agctgacacg tccctcttta agacccatcc
     3721 aagcgatggc tttttcagta tctactgtca ttcttcttcc tcctcaaaaa acggataaaa
     3781 gataagagca atcacagata atggcacata cagtattgcg attgctagta ttaacgctaa
     3841 tcgtgtgatt gctcgcatgg ctcctcctat tttttgggct catggtaagt caatgcttgc
     3901 tcactatctg acaggccttt cgtggttgga tctgtgacaa caccgagcaa taccaaaagc
     3961 gttacagctg tgtttgcaat atctgcgatg tttgatggta gtttaatacc taattgctgt
     4021 gctaacaaaa agatagctcc caaaatagcc atcaaggtta ctttgttttg tagtcgtaat
     4081 tttaaattga tcatttgatt tctcctctca tcatatcttt taaatcttta acatcatctg
     4141 ttaaattttt aatttgctct gtcattgtaa tcaacgtttt attttgctca gcgtgctctt
     4201 caagccgccg agcattttgg cgtgtaacaa tttttaaatg ctctacctca gattgcaaca
     4261 aagtaatatc tgtcgcatgc ttgatggatt ttgcattaaa aatattgtaa gtcgtgacga
     4321 tagctaaaat aaagccacca acgccaaata tcaactctgt tgccataaac cacctctaat
     4381 cttgtttaac caaatcagcg tacttgataa ctgttacttt ggcttctgac tctagctcct
     4441 ctaaggtttg tttgtcatac tcaaatgctt cgttaacgtg tacgaagact aggttacctt
     4501 caccagcctc tccgtcttcc tctttagtac tgtcgaccac cgtaaagaca tcataggctt
     4561 gatactcacc tttttgggct ggctcgatta gctcaagcat gcctttataa atgtcagaat
     4621 caatcttgcc gccgctcgtt aacatgtgga tggtttgcaa gttaatcatt cgctgtgtac
     4681 gctctgcgga caccttagct aatcctgcgg ctgtttgggc tgttttagcg gtcttagcgg
     4741 tttcctgtga gattttttca aggtcgtcta ctttttgcac ggcttcgccc attgcaattt
     4801 caacgtattc agatttttta aattcttcca aagtagcttt gataatctct gtgtcattag
     4861 ttgagtttaa gtcctgcttg attggttgag agatgactga gccatcttct gctgtgataa
     4921 taatatgtgt gcttgcgact gctcctgtgc tgtcaaattg tgggtatttt cctgtcactt
     4981 tccaatttct catggttatt ctcctttttt actttcttca aattgttcca aaatgttgtc
     5041 gataagaatg atttcagatg atgtaaattc atcttcacac tcttctaaaa agtttaaaaa
     5101 gtcaataaat cgcttggagt actcaccccc tttaatcaca atttcttcat cagctagctc
     5161 gttgagtagg ccgctgaact cgtcgagttt agtggggtct gctagcttga tgtttttgtg
     5221 ctcatcaatg acaaacttgc catctttgtc tttttgagca tacagatcaa taaggtcacc
     5281 ctcatccttg gcgtactctt tgaatttatc tactactttt gcgagtagct tagcacgtcc
     5341 gcgattagca cgcatattag tgattttgat tttgtctagt acactatata gtgtattgag
     5401 ttctttattt tttattgtta aatccattgt ttctcctaaa taattttttg cacatagtta
     5461 ttcagctcac tattaacagc gttgataaag tttctgtgag acggattcca tccaacatta
     5521 gacaaatgcc tccaacacct actaagcgct actacagccg catacaagtc gttcatgtca
     5581 agcatttttg ccatcttgtc tggtctaaac ttaaatcctc gagtaatatt aaaatcatcc
     5641 acaactaaaa cactatctcc gtaaatctct gtttggtcga ctgccgcagt gtgttgatag
     5701 ccttctgcgt acctaaatga ccttagccct gcaaaacgac cggaagaagc cgagttaaca
     5761 ccgtcaccag atgaggttat cccgatcgat gcatacaacg ctgaccctgt ataacctttg
     5821 ggcgtcgcat tactaaaatg tacaaaggca gtatgtgtgc catctttacg tactaaggca
     5881 ttgtttttgc tattaaaatt aattgtggca tcgctattaa agtccatctt agctgtattt
     5941 aagtcgataa gcatcgctcc attacgagcc ttaatgacct taccctcgag caaatcagtg
     6001 atagcatagc caattttagc tttgataaag ttagcgtcta aaccaacgat actgctggcg
     6061 tttagattaa tcactctaat cttagcagcg tcaatcactc ctgcgataat ctggtcagcc
     6121 ttgattttga tagcgttggc aatctttgtg gtaaaagcgc cgttgacagt ggtattgcca
     6181 tcaagagtga tgtttttacc agctatttgc acaccgtggg agtttaggtt aatcgctgag
     6241 attatctcat taccagacat cttgctctta ggcaacttgt ccttaatcgc gagcatgata
     6301 ctatcaccag attgccgcaa gagcgactgg accttctcca aggtcacaga ctgatctatc
     6361 aaagtcttta gctgagtaaa gttagaggag atagtgttat cctgattgga tatcctgcgc
     6421 tcataacccg ctacagtctc tctcaaactg ttgtaattac cctctgcgga ctgtaatcgt
     6481 cgttggtaac tgtctaagtc ttgctgcaca cgactgacag cacctgccct gtctctaatc
     6541 tcttgtgaaa tttggctagc ggttgtctgt tgtaccgctc ttagtccgct aatttgtgac
     6601 tcgagctctg tcctcgtgcc ttgatttgag cgagtaaact cagcacgtaa gccattgagt
     6661 ttgttttcgt aggcctctgt agtgccgctt gaggttgttg tgatcttagc cgataactgt
     6721 cttagctcgt tatcatactt ttgtgataat cctcgagcgg ttgtttgtat ctcagcttgt
     6781 aaaccgattt tatcattggc cattgtggct tttagcccct caataccagc ttggtagctt
     6841 gacgatagct gtctatctgc atcttggtac tcacgtctaa tgcctgagac tgtctcgttg
     6901 ataagcgcaa gttttttatc ggtctcgcta ctaatacgtt gctgcgtgcc ctctgcggtt
     6961 ttgataatct cagattttat tgtaccgttg taatactctt caatcatccc ttgattatta
     7021 agcttgattt ttgaccaaag tttggagttt ttagtatctg ttaactcgag gctaatctct
     7081 ttgaggtctt taaatagtcc agtcggatta cctgtcccct cgacaaccac gggcgccacg
     7141 tagttagttg gtttaccccc tcgctcaatc atgagctggt taaagcgagt tgtaccgata
     7201 catctgttat tggctatttt aacgcttttt gtgtcaccat cagccgtaaa tgtataataa
     7261 gcacgtccat ctgagccgat tgttaaattt gactcgtcta ttaaaagtgt tgggtctcta
     7321 ctcaaatgtt acctcctaat ttttaccgta aattttgaca aaaaaacttt tttctaatgc
     7381 tctaaaaaaa caaaaatgac tatcttgtaa tgctagtatt ttatgtcctg ctaaaaaaat
     7441 cgtattgttt tttgttgtgg gggttttaac aaaaaatgca ttattgatta cgattttata
     7501 aaaaggataa atatccaatt ttttcccagc gcttgtcagc aaaccgtcaa aaagcagatt
     7561 ccacgaccgc tgatagacaa tcgtattatt acaaataata cgatcaatcg ttttgttatt
     7621 aataatgata ttatttaaat cttttaacaa attatgacct ctcaaacacg atcatgccac
     7681 tggtattgct aggcacctgt cctttatcaa ccactttaac ctcaagatat tgtccggttt
     7741 gcgtgtcttt tagcttaccg atattattaa gctgtgactg tatatcagct tgtctgagat
     7801 agccagacaa gcgctcatta agaccagcta tgtcactaat ctcatgctta tgttttttag
     7861 cagcataatc ttcttttgct tgcttttttg tcactacttt gacttcacca ggagtagtca
     7921 gtaagcgacc tgtggaagta gcagtcacgt agttagcacc aacataagtc accgctacct
     7981 ccaaataatt gtctgcttgg gtggtagtgt tatgtattgt aatcaatact ttgtcaccat
     8041 ttttagtaga aactgtagat tcgttgacat accaactcgc cgaatagctg ggttttgcat
     8101 aactttttag taagctatct gtataactat agctgcttgt aaacaccttt tgagatagcc
     8161 ctaaaaagtc attaatagct ttaacatctg cggaaccgac gtttttaagt tcagattttt
     8221 tgacataatc ttccagattg atgccgttga catcaccagt gtcgcctttt tctcctttcg
     8281 gaataacgac cttggtttta tcactaaagg tcagctgtac gccctctgag acacgttgtt
     8341 gacctgtgat agtgatacta tcacctttag gtcctgactc acctttaacg tttccaagat
     8401 ctaactctga ttcctcttca atttttagtt ttaaatgacc ggattcatca acccgagcac
     8461 tctcaacgct cttacctcta tccccttttt ggccattggg gatattaaag gttttttgag
     8521 tgtcgtctga tagtttgata gtgagcgtct caccatcttt ggtgatgtca gtaatacttg
     8581 tacctttgtc acccttttga cctttgatat ttccgagctt agtctctttt tccccaatcc
     8641 ataccgataa gtcaccattt tcggatagct gtaccttagt gatagattct ccttgcggac
     8701 cttcgtagta aggcaggtca ttgtaagtca atttgccatc accgactttt agcctgtgag
     8761 tgtctagctc aacaactagt tcaccatcat caacaacagg atttaatttt tgccactcgg
     8821 cagcatcctt gcggtcaaat aagactttaa ttggtattct ttcttctagc gtcatctgtc
     8881 cctccttccg tctaaaataa tttttggttt atcggactgt ttgccgataa tagttgcacc
     8941 tttggcatct gcaatctctt tatagctcat atccagggcc aattcctgca cctccgacgc
     9001 gtttaaatct atctgcttag atttatacca gtcgccagtt aaaacagccg tgtagctcaa
     9061 aggataaacc tctatagact gtttatcctt agcgacctca aacgtctgtg catccatttt
     9121 tgctttggtt ggtgtcagta ctaacttaac tcccttgtta ttaatttgcg tcaatgtgat
     9181 agccactttt ttgagtagct cacacgtttg actaaagcta atcgtgtacg tctcgccacg
     9241 tttaaaacca ccgtcattag cttcaagctc gatatagtct tggtcatagg tttttacacg
     9301 gttagggtcg ccaaccaaga ggtttttgtt gtagtgggtc ttaccgttgt tacctaaaat
     9361 ttcggcgttt agacgggacg tctcgctcgt ttcactgact ttgtttttta ggtcatcaaa
     9421 gctttgttta atagacggga tgtcatcaac tttgatagtt tcggttattt tcttgatcgc
     9481 ttcctctggt aacgctaggt ttttgagggt ggctcggaat tcatcgagtt ctttttggtt
     9541 acgttcgtct agttcttgct gatgttgttt gagcttttcg atttctttga ttgcttcttc
     9601 aacagccgtt ttagcgatat cggagttata acttctaacg acttcgaccc agtttttgcc
     9661 gtcccaaata agcatgattt tatgaccttc atgttctggg tcgggcttaa accagatatc
     9721 ccctattttt accttgcttt tatcaggttc gttttcgcta taaaagttgg tattaaagcc
     9781 acctgcgcta ggcaattcat cctttaaaaa ttgtcccaga gtatcaaaaa cggtatcaga
     9841 aacactatct gtcaaatgtg actgtaattg agcttttttt aggctgtcag aagcatttaa
     9901 cctatcgcct aatttaatat ctatcgcttt attgcttagt ctgtcccaag tgatttcgaa
     9961 aactctaact tcgtagtcaa gatttcggtc ttttcggaca actctcacag tatcgccaat
    10021 atttgctttt aagtaagccg aggttgtttt aaaaacagct cttggtcttg cgtgatcaac
    10081 taaatactca tacgaacgtt gaagcaactc ttctgggtca tcagaatcaa tatcaacaac
    10141 accaatctta ggtacttttt ttcctttgat gtttattcca tactcttccg tagcttctgg
    10201 taattctaag tacagctggc cggccggttt atctagtgga ttgtttggtt tagtccaaac
    10261 cacatctttg aatgtaattt tccgaccgta tccggctttc ccaccttcat tttcttcagc
    10321 agaggacact tcttgaccgt ttcctcggcc aatgacagct gtaattaatt ccgctttttc
    10381 gttttgttta agtatcttta aggcgttgtg tccgtaaaca acacgacgtc cctccgctac
    10441 accgattttc tttttaaaat caatatacct agcacctatt tcattattgt tcatctcgac
    10501 aaaaaactgc atttccagtt gccaggctga gcaaactttt aacaaagaat caaacacaga
    10561 atcataataa aaattagtag atgattttcc tgtttcagca acatatcgag cgtgccaatt
    10621 agtgtcttta agcaaatatt tgataacttc tcttgcatct ctttttctag gccttttatt
    10681 ttctgctact gctttcctaa gttcctcaat acctgattgg acaccgctca aaaccgttgc
    10741 gttgccttcg gtttcatcac gcacaataaa aaagaggtga aactttcgtt tgtcctcttt
    10801 tgtcggcact gccatatatt cagactgctc taaaatatcg tcaggcaacg cttttaactc
    10861 agccgttaat aagtcagata cataattagt atctgtaagc gtctgttttt ggatgactga
    10921 cttacaagcg tttttccgga tgattttgat tagtttttca tctctgtcaa aaagataaat
    10981 catagttgtt catccctcca ttcaacgctt tcaacagcag cgtttgttgc ttggatggta
    11041 tcaccgtttt ttacataaaa ttcttctggc acagacagat gaaggagatt tgaaagagca
    11101 agattattgt tatgtttaat aacaacttcg tcgtctaacc attctatagt gattttatct
    11161 ccgctgccat aatgcccttt aagcttcatc ctttcactgc cggctgttat ttcaatctct
    11221 gcgcctccag ttgactgtaa aacaatttta tttggaagca ccttgtcagc gtgcgttaag
    11281 gttataggcc ctctagatgt ctttaaagct ccttttttgt atggatctgg aatcaacaat
    11341 gtaaagctag aaacgagcgt tagagactgt tcggagtcgt caggagcaga ttttaaaaac
    11401 cctttataag taaagtcttt ttcatcagca aaagtcaaag ataattcacc tcttagattt
    11461 ttattcagtt ttgcaaaagc ttcccttaaa ccctctgaat tgtcagatgt cagttgaaag
    11521 gttactgtaa tttctctttc tttgtcctgg atgtttgaaa tgtaaacacc tctacggcta
    11581 ggaatagcaa tagtttcaat ttcttggcta acaataccac ggcctgacac atgtaattgc
    11641 ctataccctg gtattaattc attaagcggt ttcccgttta cggacatatt atcagatggc
    11701 aagcgagctg ttacactcgc accacctttt aaatttacat aatcatacat taatagacct
    11761 ctgttaatcg tgctgtagct ctctgtctat ctgtaatgtc atctacaaaa agaccataag
    11821 ctctgtttcc tagttctagg ttgagttcta acggttttgc ctgatgtcca agatctactt
    11881 cgacacctgt tgccaccgct cctgatatag tactactcat gtcagcatcg aacagtgaat
    11941 tgccatcaac aagtttagat atgctatcag ccatcccaga aacattgttt ttaacttgac
    12001 cgaaaccgtt tgatagaccg ttattaagtc ctgacataat tgccttacca gctggaataa
    12061 gcaggcgtct atcgtaactt ataggtcctt tgtgcgactt gatccaagag gcaatcccgc
    12121 ctacaaagct agtgatagcc ccccacatag attttagacc gcttaaaaag ctttgcatga
    12181 tggcgctacc ggctgaaaat aggttgatac ttgataaaaa accaacgact gaattccacc
    12241 cgttaacaat gaagttttta actgcattaa taccattact tactgcgttt ttcatggcat
    12301 ccattgcgcc agagacaatc gctttaatgg cattccatac gctttcggcg gtggctttaa
    12361 cagcattcca tacagagtcc caaatagatt ttaaagcgtt taagattgtt tcaataactg
    12421 atttcaaagc attgaataac gtttctccaa ttgttttgat agcgttccag gctacttcga
    12481 atattgactt tatcgcttcc caagccgctt gccaatctcc ttggataaca gccgtgactg
    12541 ttctaattat ctcagcaaca acatttattg ctgtagaaac gattgttgtg ataactgtcc
    12601 aagctgactg aacaagtatc ttaatgacct cccacatggt ttggataact gtttttataa
    12661 tttcaaagcc agctgtaata attgctgcta aagtagtaag cgccacttgt acagtgttag
    12721 atataataac ccaagccagc tgaatataag tcttaataaa ctcccacacc aatgtaattt
    12781 gcaattttat aatttcaaag cccgcctgca ctacaggagt caaaattgct aaagcagatt
    12841 ggaaaattgt tacgataata ttccacgtgt cagtaaagaa ttgtttaata tcttcccaaa
    12901 taggctttat ttgttcgcct agagctgtaa agaattccgt caaagagctc cataaatttt
    12961 taaaagcatc gacaataggg atcattcctg taacaaaact ttcccaaaca cctagagcag
    13021 atgattttat cccttcccac agaggtgaga agaaatctgc caatccttgc caaaccgctt
    13081 ttaagaaatc aacgactgaa gcccatactg ttttaacgtt atcccatata ctcgaagcgc
    13141 cgttttttat tgtttcccat agatttgaga agaagcttgg agcggcagcc catgcgtttt
    13201 tgatatactc ccatgctgta gaaaatactt gttttacagc ttcccagatg cctgtaacgg
    13261 cgtttcggaa tccttcattt gttgtccaaa ggtatgttag tactcctact agagccataa
    13321 ttcccgctat aatcagcgtg attggtcctc ctaaagccgc tataactgcc ttaaaaccgg
    13381 tcaatgctgt tcctgctgtt ttaaatgctg tcaccaaccc tttgataaat ccaaatgctg
    13441 ttgctagcat tcttattccc gttattattt tattgataac taaaaataca ggaccgatgg
    13501 tagcaaggaa gatcccaaaa cttatgatac cgtcttggac ttttgggtct aaatcactaa
    13561 aagcttgagt gattttcttt attccttctg caagttttcc aatcctcgga gctagatgtt
    13621 tccctataac ggttccagct tcaaataagg catttttaag taattttagt tggttagcga
    13681 aactctgcga agcagcatct gcttcttttt gcagagcagt gccatccgcc cacgccttat
    13741 ttgctatgtt aaacgatttg gctagtaaat ctcccgcacc agaaagacgt gctaaagtgt
    13801 caatctctcg cacggaatta atacctaaat ctttcaaagt ttctgtgaca tctccgccac
    13861 tctctttgat ttttcctagt cctttcacaa agtcaacaat agcttcttgt gggttttttc
    13921 tccacgtttg ggcaaattct tccgctgttt taccagctac tgaggcaaat ttctgtaaac
    13981 cttcgcctcc agaaaggaca tctgtattca ttttctgcat gactcgagaa aatgctgaac
    14041 ccccagcttc tgcattgata ccaaccgagc tcattccagc cgccaaacct gctatttgag
    14101 cttctgtcaa tccaacctga tgaccagtac cagccaaccg caatgccatc tctgagattt
    14161 ccgattctgt tgtagccatt ttattaccta aagctacaat ggttgaccct aatctgtgaa
    14221 actgtgtttg tggcatttga gtgatgtttg ctaatcgtgc cattgcatta gctgcttgct
    14281 cagatgacat atttgtagca gtccccattt gagcggcgat tctcgaaaag ttgattaggt
    14341 gtttaccacc ttcgtccgta cggataccaa gttgtcctgc tacctctgct agattggcaa
    14401 tctcgacagc gctgtttggc atctcccgag acaaagacat aatttgcttg ctaaatctat
    14461 ttaaagcatc tcctgatatg tccgttgttt tgcggacacc aattaatgcg gtgtcataat
    14521 ccgaaaacgc tttaagtgat gcgcccccaa gggcagtcag aggcaacgtc agacctgctg
    14581 tcagcgcctt cccgacaccc ccaaaggtgt cgccgatacg ctgtagcctg ctccccgttg
    14641 ttttttgtaa ttcgtttaac gcgttttttg catcttggac acctgctcta aatccgctgg
    14701 cgtctgcttt aattaacgcc gttaacgtaa agtctgcaac accggccatt tattcctcct
    14761 attcatttat gacacgattt aaatcagcga tagataactt tggttttttt ggctttgtat
    14821 caaagatagc gtcaaaagct ttccctgcat cataaaaatc tttaaaactc ttataagccg
    14881 aacggacatt ttttcctgtc ccttttgtcg ccttaaccgc ttgattaaac caagcttgct
    14941 tagctaacat agtctcctcc tcttgcattt ttacttgatg agccaagtca taaatacaat
    15001 agtcatgcca tgtcagcctc ttggcttcca ataagctaag cccaaacctt gccatagcta
    15061 tcgccattaa atcgtcaaag gagtagttta tttggctttc gtcactgctt cgattacttg
    15121 gtttcctgcg atagcttgct ggaggactgc atcctttttt atttccgcaa ctacttcatc
    15181 gtaaaaccca atgtaagttc cgtttacaat cgcttcttcg ataaattttt cgagttcttc
    15241 attggatggt ttcgttttct ccgtgctcgt agcgcatttt aaaataaaaa gcaagacttc
    15301 cggatcttta aatgcgcttc ctgcctcaat ttttgtcatc gaacctgcac caattcctac
    15361 accatccatt tcgatcgctc tgtgtttatt tgcgtatttt aaaaaatcaa acccaaaaac
    15421 gaggtcatac gttttcttac caacagtgat ttccatttac tctccttttt acatttcaaa
    15481 actgttttct tttttagttt cttccggttc agcaccacct ctagccatgc ttttgtatct
    15541 gtacagcaca tctgatactg cttgtttttg ctctgatgtc agttcatcta cgccttctac
    15601 accgtttccg ttaattgcgt aagtcataga tagttctact tgaccatctg ccggtgctga
    15661 aatttcaaat gatgtaaagt atccttggaa atattccgct ttatattttt gatgaccaga
    15721 atccttagaa gtcaaatcaa cttgccaaat ctccaccaca tcgccatctt taaaatattt
    15781 tcgcaactct tcccaaattg ctgtcgtgct ttcatcgctc gtataagcaa aagacttaat
    15841 atcaatggtg ttttctccat cagacaacga gttaataatt ccgtcttttg tttttgttgc
    15901 ctcggtctct ttctccatct taatagaatg ttctgtttgg aatcgcaatt ttgcagcatc
    15961 ttttgtctca acatcatcta atctacgaaa gaatagcaaa aagctttttc cttgaattaa
    16021 ttctgccatt tagtttcctt tctttgtgta agttaaatag acatctaata ccgtatgtaa
    16081 caacggtgtc gtgtctgagt tatcgggtaa agtctgctcg ttaatacgat caaccctaaa
    16141 gttataaccg tatgcagatg tcagagagat gattttgtca tgtaaattag taacgacatt
    16201 atctatttca gagcgttttt ttaactctcc ataaacatgt attgtctgcc taattacccc
    16261 catcatttcg ctgttattgc taggcgtatt agatgactcc ccaatgtaag caaatggata
    16321 tttagcattg gcattcggca aataatcata ggtattttta gttaccgcca aacactcttt
    16381 aaaaatctgc ctaaaaacgg cgttgttagg tgtcatttaa aggccctcct gataacgctg
    16441 ttataatcct tttcaagatc tggtaaaatt gattcaatcg ctggcctcaa aaatggttga
    16501 gccggcattt ttcttgtacc atattccaaa aaacccgagt atcctgcgtt tgaaacaatt
    16561 tctgcgcttg ctttagctgg atagtgagta tatatctcat cgtgcaagaa cccggtgtca
    16621 taaggagcaa tcctctgagc ttctgctttg gctttttctg catgattttt aacaactgca
    16681 tctgttaatc tatcaatgtt gccagaggcg tttaccagct tgctgaaagc tttttcaata
    16741 cccttccact ctatggtcac gctaggcatt acaacacctc ctccagataa aaaacaatag
    16801 cgccaagctt atttgcctgc gctttgtatc tcctgccctc atactcgcaa taatcaaatg
    16861 cttttgtata aggctgtttt aggtaaatga ctttacggtc cttttgataa tctccaaaaa
    16921 tctgcacaga cttctccgca cccatttcca tcgcaaaaca aggttttgtc tcgcttatag
    16981 tctctgtgtg cgtgtactca cctaaatcag ggtcgtattg ctcatctgtc gttttaacaa
    17041 atgtaactct atctgcatat ctcataaaaa gtataatccc cccttacgag atttatcctt
    17101 gattaagtca agttttgcca taatcatgtt gtcgtatggt tcaaactcgt ccaaaaagtc
    17161 gtagtatgtc gtcgtatgac cttccacact ctcacttttt gccctttccg cacctctacg
    17221 gttaaatcta gcaattaaac aatcttctaa aacaaaacta aaagcgctgt ctattttgac
    17281 aacgccatat ttagctttaa aatggtctgt aacacgtttt agcaacatgt taagtaaatc
    17341 atcctgttga ctgtctaaaa tgcctaaatc aagctttacg ttagctatta tgctgtctgt
    17401 gtttatctct tgcataaaca cctccaaact atccgattgt ttgctttaaa agctccaata
    17461 gctcggattt tttaagttta gcatcatact caatgcttag ctcgtcaagt ttgcttttaa
    17521 tctcactcac tttcagcttg tcaaagtcta cagacggttc taaaacaccg ccctctgtca
    17581 aaaactctac tcggtcgccc gagtaaatat cgccgacttc gtagactact tttgttactt
    17641 tatctttaaa tgctctaatt actctaggca tattgacctc ctacatttca aagctgtttt
    17701 cttttttagt ttcgccgttg gcattaataa tttgtacttc tgccaagcgt tcaaatgatg
    17761 gcaatacaat catagatact tttgtttgta cgtttacagg gtctgttgtt ttagtagttg
    17821 tgacagcaat accgttttca acgatcgaca cctctgcatc tgtggcttga ccacccatca
    17881 agtctgattg ctctggggtt gtgccaaata ccgtgctacc gagacttccg ttagggacaa
    17941 gtgtagcaac gccatctggg aagtacttgc gtgctttccc gtcatcaccg acaaacatgc
    18001 cgtctttcag gatgactttg acttgcaact catcttccag atatgtgttt aagtcattct
    18061 tggtaaccgc tgaaccctgt ggtgccatag gtttaacaac ctctacagta ttatctgcgt
    18121 ttttaatcag actaaatgtt ttagagttca tgatgatggc ttctggtgca taaccacgct
    18181 ctgccattgc ttcgatagcg gttgtaatat cggctagtgg cgtagcttga tttgcgtctg
    18241 accatttgtt tttagcttta gtcgtctgct cttcggtcat tccgtagtca atatctttca
    18301 tgacaccgtt tgacgcaata tggattttac cagatgataa aacttccatg cgcattgctt
    18361 caatacgggc tttagcggca gagataagcg ttactttgtc gttaaagata gacgccaaaa
    18421 ttgtatcaat aagttcttgg tttttagttt gcgctaacat gttgagttgt tgacggtcag
    18481 cctctttaac aagcatagcc tctttgaaaa atggcatttc ttcgtcaatc aattcaactg
    18541 acatacggtc acgtagcggc actttagtgt caaaagcagc tgctttaagt gttacaggac
    18601 gccctgctgc acctttgata aatgataact taaggcctag ttgttgttta gacggaaatg
    18661 ctttttcccc aagcgttagc tccgcctcgc ctttttgttt gtcgtaaaac cctttaatat
    18721 tttctgatgt gataatctca tgaatgtaag ccattattta cctccttcga taaattggat
    18781 gtgcggtaat ttttctttca aatctttata attttccgca atagatggat cagcaagctt
    18841 atctgcattg atagtcccac gataaacaca ggaaccgact gcatcgccat ttgttaaatc
    18901 aacatctgta agtaagatgc cgcagatgtt gttttcgcta gaaatttctc cattttttac
    18961 ttccttaacc ttttgtgtac ggtcttcgaa tacagatttt tctttgccag ctaatacagc
    19021 accagctttg ataatttttt catctagttc gctagaatct agtgttactg aaattgcttc
    19081 gtaaggtaga ttgtgtaaaa tctccttaga tgttgttact ttacgtttat tcatgttttc
    19141 ctcctaaaaa agcttggtgc tttgttgtgc tgccttacta gccaagttag caccgtaatt
    19201 agtttgtttg ctcaatccac cccctgttga cggagtggtc tggcgtacca gagccttgcg
    19261 gtcatcagcg ataactttag caaatgcgtt tgctagcgtt gttacatttg cttttgtttg
    19321 ctctgcatct aaagtcacaa ctaaaccaag cacgtcatcg ttgacgttga tttcagattc
    19381 cgcaaacatt tgacgagcta ctgctgttaa ctcattgcgt gtcttatcgt tttttagctc
    19441 ttgcaattcg tctaacagct tctgcttttc gtagtctgct ttctcttttt cattcatctt
    19501 agccattttt ttagcttccg atttctccgc ttcttgttct gacttccact ttgcaaactt
    19561 tttatcgatg atggcatcaa catctgcatc tgtgtacttt ttttcgtctt gcggttgttt
    19621 tgcttctggt accacttgct cttcaaccgt ttcaactgtt tgtgtttctt ctgccatggt
    19681 tggcacctcc tatgttttaa gtcgtccccg actataaaat ccatagcttt ttacgtcgtc
    19741 aatgcttgga cataataaaa agccgtattg ctacgacttt aaaaacttgt ttttaatttc
    19801 aatcagcagg tcatattctg attttgtgat agttaccatt tcagggttat tcacgaatag
    19861 acattggttt ctaaccctat ctaattcatc ttgctctaat accatattat ttcttccccc
    19921 acttacgttt gtaatttttc ttaatatagt taacgtcaat tgcaatgttt gtaatagctg
    19981 cttgattatc aaaacatacg cctttaaccg ctgccaattc gttatttgtt gcttggacgt
    20041 tttgttgtat aatcgctctc agctctgcaa tttgtctgtt ttgattctta atagcttcag
    20101 cttgcatggc attctctgcg ataagcaaca caataacctg ttcgagttta cgttttttct
    20161 tgatgcgttt attcattacc ttctccttta tttaactttg ttgcacacga catttcaggg
    20221 acaaaatttc ccgcagcttc taaggctttt ttgtaagctt cttttgtttc attgacttta
    20281 ttcatgattt gttgaaattc gtctttgttt tcccaagtca tttcgatatt taatgatatt
    20341 ttattcatgt ttcctcctga ttttatttta taacactgcc ataatcgacc tctccataag
    20401 ttgagcacct acaattcgga tgtagcggtg gcatggttat agctgttgcc cccttgctca
    20461 actcaaatcg ttctttatcg taaggtgtac aaatttggca tgctccaggc tcacaaacaa
    20521 atatataatg cgtaaaccca tttttcttat aagcatctaa ctggacgtca cttctaatcc
    20581 ttgcgctttc tgtcttaagt aatcttagcg cttcgtgttc tgcgacatca aagcgtctca
    20641 tcaaccgttc tttctctttt ttatatcctt gcatatctgt agcgattcga gaaagcgaac
    20701 taaaaaggct tttttgtgtc tcgtgataca atccgttatt tccccagaca cgctcggaaa
    20761 agttttttcc gtaaaaatct gcatttagga taccttttaa ccttttggca acagaccctt
    20821 gacctcccaa aattcccgct tggcgtttca tttcgtccaa agcaattttt tctcttgcca
    20881 actgtatctg gttatcaatc ttagtgtgca ttttgagtag ctcataattt aactcggcac
    20941 gcagaagttc ttctctgctt accttcattt tcagattata cacgctaagc cacagattag
    21001 cttctttgct aaagtcacga ttagcaaccg cctctttcgc catattttga taagctgtaa
    21061 catcaaaact gtcggctaac ttcttcacag tacgtttatc gagaccgtgt ttgtcagcat
    21121 agcgcatgta aaaacgatct atgttagcct cgatttgtgc ctttgactgc gtatataact
    21181 gctttaacat agcttcgttt tctaagtctg ctttcaccca tgcatccatc gcttttcttt
    21241 cgcgattata agcttcattt cgttgtttct gtgttgattt cacgtcttaa cacccccaaa
    21301 tcaaagtctg atagcgacgg gttgttagat tcctcctctc gacgttctga ctggatgttt
    21361 tcaaattctt ttcgagcatc ttccacaata tctgtgatag ccatgatggt accttgcgat
    21421 aattccccac ccaatgcttt aaaggcttca atcttttctt gtagcgactt aggtaggttt
    21481 ggcgtaaatg tgattttaag cttgctgatg tcaaagtcat caatctcttt aagcagttgg
    21541 cttacacgag cgattagttt gtacctacgt ttaagcgatt gctcaaataa agcttgcata
    21601 tcaacacgct cttgatcaag accaaacact ttccacttca gtgcctcacc ggattgttga
    21661 ccggcaaatt ttgtgtcggt catgtctggc gtattggtaa atttatggat gtcggacaca
    21721 atacgatttt tataggcttc ggttccttgt acgtcatatt gtttatatag atatttggca
    21781 tctacggacc cttcacgccc gtcttggtcg acaggaggct ctaagttaag taatctagct
    21841 ttacgcatct tacgtaagta ttcaatggct ttttcggcag tgtcgacata gccaggaaat
    21901 gatacacgac caatgattgc cagaattgca tctgacaaat cttgcatgta gttagctgtg
    21961 tcagactgcg ctgcatcata caagtcgatt aaagacaact ctgtctcgta gtcgcccatg
    22021 ccatcatctg tgttgagata ctccgtgatt ggcactgaac caaacgcatg agaggaagcc
    22081 tctccaatag gtgttagatc accatcatat tcaaacttca ggattttatt atcggtgtaa
    22141 agttcgacta tttttgttgt cccatctaat tgatttttgt tgtaatatcg cacaccagcc
    22201 aagcttgatt gctctaggtt attttgatag ataacaaaca cttcccgtgg gtccagtctc
    22261 acgacctctg tcttgtcatc catactacga taaatcaatt caaacgctcg accaacctta
    22321 gataggtctt ttaccagtct gcggttaagt tgatggaaat tatttttaac agataagtcc
    22381 tttaataagt cttgttgctg ctcagtacca tcgatatact ctacacgaat aggattcccc
    22441 accaaatagc cctgtttgag tgttgaaata tacttaccat agttatgcac agcacgaaca
    22501 tcagccatgt catcgtcttt cctacggccc atttcgctaa tggtgtggtt atttccttct
    22561 gcatagtcta aaagctcttg tatgcgtggt ttttggactt tatcgtggtg ttcaatcatt
    22621 tcacggagta gcttatattt ttcggttaac aagctttcta gactttccgc ttgatacctc
    22681 atgcgagctt cacggtggaa tctaaactct aatgttttag tctttcccgt actatctcta
    22741 aatgattctg tgtacattat tttcctttct aatatttgag tccttggcgt aaaatgttaa
    22801 aggtatttgt gctttgtttg cgtgcaatat gatacttctc aagtgcatac ctgatggcat
    22861 caacgatatg gttgttttta tctatcggtt catttaacca attaccttcc ttgtcctgtt
    22921 taaaggtata cgtgttaaac tcctcgatag tatgctcaca agatggatgt atatggattt
    22981 taaatccttg gataaactgt attccttgca tgatagaccc tttacctttt aaactcggca
    23041 caataccaga tatgccttta ctccttatct cagcaatcaa gcgtttttct gcgctatctg
    23101 cggcgatgta agatttgtgc atgtttttat ctcttatcat tttgacaata tcgtctgtta
    23161 acattgcttt ttgatagtgc tcgttgtaaa gccataactc tttgctttct aaatccacag
    23221 ctacacatat aagcgtagta gggtcttggg taaacccaaa gtccatcccg cttgacgtgt
    23281 catgttttga tactattttg tcgatatcaa aatcaatcac ttcaaagtta tcaaagacaa
    23341 gcccctcagc tactccccat tcgccatcgc agacgattct agcccgtcta ggatttgttt
    23401 tgtataaatc taagtagcgt ttcctatcga cctcatctag ccactcattt actctaaaag
    23461 tcgttgtgtc tgaaaaggta tcatcccgct ttgtctcttc atcaaaaaag acacgtttaa
    23521 gccaatgtct ttctgaccac gggttaaacg tgactgttat ctgtttaaaa aaatcaggaa
    23581 catctaaagt accacggatt gattctacaa ctgttgaaaa cttatcttct gtctctatct
    23641 ggtaagcctc ttcaaaccaa gcccagcaca aagcgccagc atcgacagta atagatgtga
    23701 tttttaactc atcatcaagt ccacggaata agattttttg tcctgttgcc ttgacggtta
    23761 tctctggcaa gctctcatta aacttaaaaa ggtgtgtaac ctttaattga ttacacgccc
    23821 atttaaaatc ggtataagta gattgtttgt tagtgtttga gtatctacgg ataaccaata
    23881 agttagccca agggtacttc agcagtctga cgataaaatt taaagcagtc gttttagatt
    23941 ttttagatcc acggctgcct ttaactactc gataaaaatt tttagaccgc caaaaagcgc
    24001 cataacctat accgatagtt ttaggcaaat caaccttgat ttctagcttt ggtttagtct
    24061 ggtatgtcgt cttcattaac aaacaccacc gttccagaat gctctaattc acgtttttct
    24121 gagtaagctc cattaacttt ataaattcta tccctagccc taccctgttc ttcgtgactt
    24181 ggggtatatt ctcttttcgt gtggataacc acttgacctg tcagcatatc tgtttctttg
    24241 aattcagata tttggatttc tccacgggct atcgatgtat cttgttccaa cgtttctgca
    24301 acatcttgaa tacggtctcc tttagtatct tttgcctcca aaaaacgttc cttcattgct
    24361 ttttgaattt caacattttt caacaagcgt tgaccttggc tataagcgct tttttcagaa
    24421 tatccagctt gttttgcaga ctcagtagcg ttaaatgtgg tgatgtactt atccacaaaa
    24481 cgctgttgtt tttcggttaa ttcctcgtat gcgattttcc accacctcca atccataata
    24541 aaaagtcacc acaatgtgat gactaattgg ttaactatag ataaatagcg aatgaatgct
    24601 aagcctattg cctaccccat tctgggacac ttctatttat cgaacaggaa cagtcggaat
    24661 cgaaccgaca catcttcttc tggctcttcg aaaagagttt tcggacttag ctattgtccc
    24721 gaagcaaggc gctaccctta ccgttttcca atcacggttc atgttccaaa ggtttagaag
    24781 agctaagacc tctcacaaac gctcttctac agaccttgca cgaatcgaac gtgccactgc
    24841 actcaatatt tagtgagtat ttcctaatgc gaacgcaagt ccaaataaac agtctaaata
    24901 ttattaacgg tgccgtttcg ccacaaaact taagcccacg atagcttatc acaccgtgca
    24961 cagtgcaaca actcacttcg gccgaatcct caaccgaact atcagctaac cacaagcaag
    25021 gttgcgaccc ttgttttact tgcggttaat caatcgactt agcgctggta cgcatgttaa
    25081 gaggcgttgc taagtcttaa tcattaacac cgaacccaga ttgcgtattc tcctcaaagg
    25141 aacgccaatg tcaaataagg gtgttaattc acggtggaca tcgcaaagtt ccgtgattct
    25201 ttttgctttg attacattcc gcaatgtcac agcgtgtaat ctctgggtga ttgagacggc
    25261 aggattcgaa cctgcacgtc tcacatacca taaaataaca agtttgatcg tagttaaagt
    25321 tggcgactaa atgaatagcc aattggttaa aaggttatct cttcttgcta ttttgctata
    25381 ctacaatatt aacacagcta ttagtattat gtagtatcaa tttgtatcta attagtattt
    25441 tttagtatca attccagact ttcctttcct cg
//
LOCUS       DAUGOH010000022        25441 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUGOH010000022 DAUGOH010000000
VERSION     DAUGOH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25441
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.022"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            77..727
                     /locus_tag="VH957_001051"
     CDS             77..727
                     /locus_tag="VH957_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8558969.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETQFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            730..1398
                     /locus_tag="VH957_001052"
     CDS             730..1398
                     /locus_tag="VH957_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8558970.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            1407..2639
                     /locus_tag="VH957_001053"
     CDS             1407..2639
                     /locus_tag="VH957_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8558971.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSMMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            2933..3811
                     /gene="mvk"
                     /locus_tag="VH957_001054"
     CDS             2933..3811
                     /gene="mvk"
                     /locus_tag="VH957_001054"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEQ8558972.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            3793..4737
                     /gene="mvaD"
                     /locus_tag="VH957_001055"
     CDS             3793..4737
                     /gene="mvaD"
                     /locus_tag="VH957_001055"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEQ8558973.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            4730..5743
                     /locus_tag="VH957_001056"
     CDS             4730..5743
                     /locus_tag="VH957_001056"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEQ8558974.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILIPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            5730..6719
                     /locus_tag="VH957_001057"
     CDS             5730..6719
                     /locus_tag="VH957_001057"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEQ8558975.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(6949..8226)
                     /locus_tag="VH957_001058"
     CDS             complement(6949..8226)
                     /locus_tag="VH957_001058"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEQ8558976.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(8213..9388)
                     /locus_tag="VH957_001059"
     CDS             complement(8213..9388)
                     /locus_tag="VH957_001059"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEQ8558977.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALVRQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTADPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMNNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            9597..10436
                     /locus_tag="VH957_001060"
     CDS             9597..10436
                     /locus_tag="VH957_001060"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEQ8558978.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            10516..11013
                     /locus_tag="VH957_001061"
     CDS             10516..11013
                     /locus_tag="VH957_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEQ8558979.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRMTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNLYDFTVT
                     ALKHK"
     gene            11333..12562
                     /gene="clpX"
                     /locus_tag="VH957_001062"
     CDS             11333..12562
                     /gene="clpX"
                     /locus_tag="VH957_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEQ8558980.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            12572..13171
                     /locus_tag="VH957_001063"
     CDS             12572..13171
                     /locus_tag="VH957_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEQ8558981.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            13319..14062
                     /locus_tag="VH957_001064"
     CDS             13319..14062
                     /locus_tag="VH957_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558982.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(14120..16219)
                     /locus_tag="VH957_001065"
     CDS             complement(14120..16219)
                     /locus_tag="VH957_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8558983.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIKQKDQ"
     gene            16597..17280
                     /gene="rpiA"
                     /locus_tag="VH957_001066"
     CDS             16597..17280
                     /gene="rpiA"
                     /locus_tag="VH957_001066"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEQ8558984.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPTAG"
     gene            17357..18568
                     /locus_tag="VH957_001067"
     CDS             17357..18568
                     /locus_tag="VH957_001067"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEQ8558985.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     AAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLGHLK"
     gene            18587..19027
                     /gene="arsC"
                     /locus_tag="VH957_001068"
     CDS             18587..19027
                     /gene="arsC"
                     /locus_tag="VH957_001068"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEQ8558986.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            19011..19820
                     /locus_tag="VH957_001069"
     CDS             19011..19820
                     /locus_tag="VH957_001069"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8558987.1"
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILSEL"
     gene            20483..21196
                     /gene="deoD"
                     /locus_tag="VH957_001070"
     CDS             20483..21196
                     /gene="deoD"
                     /locus_tag="VH957_001070"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8558988.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            21189..21977
                     /locus_tag="VH957_001071"
     CDS             21189..21977
                     /locus_tag="VH957_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEQ8558989.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(22057..22962)
                     /locus_tag="VH957_001072"
     CDS             complement(22057..22962)
                     /locus_tag="VH957_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8558990.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            23184..23720
                     /locus_tag="VH957_001073"
     CDS             23184..23720
                     /locus_tag="VH957_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8558991.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     SAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKVPTGEFE"
     gene            23997..24689
                     /gene="pyrF"
                     /locus_tag="VH957_001074"
     CDS             23997..24689
                     /gene="pyrF"
                     /locus_tag="VH957_001074"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEQ8558992.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            24747..25376
                     /locus_tag="VH957_001075"
     CDS             24747..25376
                     /locus_tag="VH957_001075"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEQ8558993.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLNAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
BASE COUNT         7931 a         4502 c         5203 g         7805 t
ORIGIN      
        1 atatagttag aaataaagat aaccgatcat tgcagagatt taagcatttg ttgagaaaat
       61 ttgttataat aagcgtatga aagaaagact agaacattat tctaccagct ctatatatag
      121 cggatttgaa gtgtacttgc cgttggtact acagacaata acagatgtga ttattgctga
      181 gaatatcaaa agcaaaaaag aaacagggtt taaactatac gaacacttta catcccgtat
      241 taaatcggaa gcttcgatga ttgaaaaatg tcaacgcaaa cagcttcctc taacaagcaa
      301 atctgcgtta aaaatcatta aagatagtat cggtattcgc attatttgtg gttttattga
      361 tgatatttat cggatggtag acttgctcaa aagcattcct ggtatgtcag ttaacactga
      421 aaaagattat attttaaatg ccaagcctaa tggctataga tcatatcatc tcattttgga
      481 attagaaaca caatttccag atattttagg ggaaaaaaaa ggatgttatt ttatagaagt
      541 gcagttgcga accattgctc aagactcttg ggctagcttg gaacatcaaa tgaagtacaa
      601 acatcaagtt gctaatgcag aaatgattac aagagagtta aagcgttgtg cagacgagtt
      661 ggcatcttgt gatgttacca tgcaaaccat tcgtcaattg attcaagaaa cgacggagga
      721 agagtaacca tgaaaatttt attagctgaa gacgaatggc agatgtctaa tgttttgaca
      781 actgccatga ctcatcaagg ttatgacgtt gatgtggttt ttaacggtca agaggcaatt
      841 gataaagcca aagacaatgc atatgatatt atgattttag atatcatgat gccgattaag
      901 tctggcattg aggctttaaa ggagattcgc gcttcaggaa attgctcaca tattattatg
      961 ctgacggcta tggcagaaat taatgaccgt gttaccggac tagatgcagg agctgatgat
     1021 tatctgacta aacctttctc attaaaagaa cttttagcta gattaaggtc gatggaaaga
     1081 cgagtagaaa gttttactcc tcaggtatta caatttgctg gtgtcacatt aaatattaat
     1141 gagcaagaac tgagtgccgg taatgctata cgattagctt ctaaagaagg taaattaatg
     1201 gcctttttaa tgttaaatca aggaaagtac ttggatacta aaacacttta ccaacatgtt
     1261 tggtcagacc aagaagatta tgatacttct attgtttggg tttatatttc ttatcttcgt
     1321 caaaaattat tagctattca agcaaatgtc attattgcag gtgataaaga tactagctat
     1381 tgtttattag aaaaatagga ggtgacatgt ttaatcgtat ccgtattcgt tttatcatga
     1441 ttgcttctat tgccattttt attattttaa gttcaattgt tggtattatt aacacggcac
     1501 gctgttacca aagtcaacaa gaaattaacc gtattttaca tttaatttcc tcaaataaag
     1561 gtaaattacc tgacactacg gaaagctcta aacgacttgg aacgaaactg tctgaagata
     1621 gcctaagcca gtttcggtat tatagtgtca tttttaatgc taatggacat ctactttctt
     1681 ctaatactgc taatatttca gctttagata gagaagaagc ccaatatttt gctagacttt
     1741 ttgctaagtc tggggaagaa aaaggcagtt accgtcacca agatagtgtt tattcgtact
     1801 tgattactca gctgccaaat gaagaaaaac tggttgttat tttagatact accttttatt
     1861 ttcgtagtgt aggagattta ttagctgttt caatgatgtt ggcctttgga ggatttatct
     1921 tttttgttgt tttagtgagt cttttttccg gtatggtcat caaacctttt gtccaaaatt
     1981 atgagaagca gcgccgcttt attactaatg caggccacga gttaaaaaca ccactagcca
     2041 ttatctcagc caataatgaa ttggtcgaat taatgactgg agaatcagaa tggaccaaga
     2101 gtacaagtga tcaggtgaag cgattgacag gcttgattaa tcaaatgatt actttggctc
     2161 gtttggagga acagccagat gtggtattac atatggtaga cttttcagct attgctcaag
     2221 atgcagctga agattttaag agtctggttt tgaaagatgg taaacgtttt gatttgacga
     2281 ttcagccgaa tattatgatt aaagcggagg aaaagtcatt atttgaactt gtgacaattt
     2341 tagttgataa tgccaataaa tattgtgatc ctaaaggctt ggtcaaggta tctttaacca
     2401 ctattggaag aagacgaaaa cgagcgaaat tagaagtttc taatacctat ttggaaggaa
     2461 aatccattga ttacagccgc ttttttgaac gcttttatcg cgaagacgaa tcccataata
     2521 gcaaagaaaa aggttatgga attggtttat ctatggcaga aagtatggtt aagttattta
     2581 aaggaacgat aactgtaaat tataaaaacg atgctattgt ttttacagtg gtgatttgac
     2641 ttaaacattt ttcagtacct ttagctagta ataatgtcta ggtaaaggta ataaacgatg
     2701 cttaaccagc ccatgaggct ggtttttaac gtttaattta gtagaagagt gattaaagaa
     2761 ggtagtttga aataagaaaa tttttgttat gatcctaaaa agagtagata gtctttattg
     2821 ttaatttcgg tgaagaaatg attttaaaaa gatatatcat cgcattttct aatcatttag
     2881 tgtaaaatag taaggtaaaa gtttagaaga attagtaatg aaaagataaa aaatgaacga
     2941 aaacattgga tatggtaagg cacacagtaa gatcattttg ataggtgagc atgctgttgt
     3001 gtatggctac ccagctattg ctttgccttt aacagatatt gaggtggttt gtcatatttt
     3061 tccagctgat aaaccattgg tctttgattt ttatgatact ctatcaacag ccatttatgc
     3121 tgccttggat tatttgcagc gactacaaga accaattgct tatgagattg tttcacaagt
     3181 gccacaaaag cgtggtatgg gatcttcggc agccgtttct attgcagcta ttagagccgt
     3241 tttttcttat tgtcaagaac ccctctcgga tgatttgttg gaaattttag tcaacaaggc
     3301 agaaattatt gcccacacca atcctagtgg tttagatgcc aagacatgcc ttagtgacca
     3361 tgccattaag tttatccgaa acattggctt tgaaactatc gaaatcgcct taaatggtta
     3421 tcttatcatt gcagatacag ggattcacgg tcatacacgt gaggccgtca ataaggtagc
     3481 acagtttgag gaaacgaatt tgccctatct ggctaaacta ggagctttga cacaagccct
     3541 tgaaagagcg attaaccaaa aaaataaggt ggctatcggt cagctcatga cacaagcgca
     3601 ctctgcttta aaggccattg gcgttagcat cagtaaagct gaccaacttg tggaggctgc
     3661 cctaagagca ggtgctttag gcgctaagat gacaggcggt ggcttgggtg gctgtatgat
     3721 tgccctagca gataccaaag acatggccga aaaaatcagt cacagattaa aagaagaagg
     3781 agccgtaaac acgtggatcc aaatgttata accgtaacat cctatgctaa cattgctatt
     3841 atcaaatatt ggggaaaaga gaatcaagct aagatgattc cttcgacctc tagcatttct
     3901 ttgactttgg aaaacatgtt caccacaacc agcgtttcct tcttaccaga tactgcaacc
     3961 agtgatcagt tttacattaa cggtgtcttg caaaatgacg aagaacatac caaaatttct
     4021 actatcattg accaatttcg ccaacctggt caggcttttg taaagatgga aactcaaaat
     4081 aatatgccaa cagctgcagg tttatcatca agttccagtg gcttatcagc cttggttaaa
     4141 gcctgtgatc aattatttga cactcagcta gatcagaaag ctttagcaca aaaggccaag
     4201 ttcgcctcag gatcatcttc tcgttctttt tttggcccag ttgctgcttg ggacaaagat
     4261 agtggtgcta tttacaaggt tgagactgac ttgaaaatgg ccatgattat gctggtctta
     4321 aatgctgcga aaaagccaat ttctagccga gagggcatga agttatgccg cgatacctca
     4381 actacatttg atgaatgggt agaacaatcg gcaatcgatt accaacatat gcttacctat
     4441 ctcaaaacta ataattttga gaaagttggt cagttaacag aagctaatgc cttggccatg
     4501 catgccacga caaagacagc caatcctccc ttttcttacc taacaaaaga gtcttaccag
     4561 gctatggagg ctgtgaaaga actgcgtcaa gaaggttttg cttgttattt taccatggac
     4621 gcaggtccaa atgtgaaggt cctatgttta gaaaaagact tggctcaact agcagaacga
     4681 cttggcaaaa actaccgtat tatcgtttca aaaacaaagg atttaccaga tgtctaatta
     4741 ttgtgtgcaa acaggtggga aactatacct cacaggcgaa tatgctatct taataccagg
     4801 acaaaaagcc ttaattcact ttattccact gatgatgaca gcagaaatta gcccagcagc
     4861 ccatattcaa ttagcttcag atatgttttc ccataaagcg ggcatgacac ccgatgcctc
     4921 ttatgcactg attcaagcaa cggttaaaac ctttgctgat tatctaggac agtcaattga
     4981 ccaactggag ccattttccc taatcataac aggaaaaatg gagcgcgatg gcaaaaaatt
     5041 tggcattggt tcaagtggta gcgtcaccct cttaacctta aaggccttat cggcctatta
     5101 tcagatcact ttaaccccag agttactctt taaactagca gcttatacct tgcttaagca
     5161 aggagataat gggtctatgg gggatattgc ctgtatcgct taccagactt tagtcgccta
     5221 tacctccttt gaccgagaac aggtcagtaa ctggctgcag accatgccct taaaaaaact
     5281 tctcgtcaaa gattggggtt accatatcca agtcattcaa ccagccctgc cttgtgactt
     5341 tttggttggc tggactaaaa tacctgctat ttcaaggcag atgattcaac aagtgacagc
     5401 gagcattacc ccagctttct taagaacaag ttaccagcta acgcaatcag ctatggtagc
     5461 tttgcaagaa ggtcataagg aagaactcaa gaaaagttta gcaggagcaa gtcatctcct
     5521 aaaagagctt catccagcta tctaccatcc taagctagta accttggtag ctgcttgtca
     5581 gaagcaagat gctgttgcta aatcttcagg ttctggtggt ggagattgtg gcatcgcgct
     5641 tgcctttaat caggatgcta gagataccct tatttccaaa tggcaagaag ctgatatcgc
     5701 attactttat caagaaaggt ggggagagaa tgaccaaccg taaagatgat cacatcaaat
     5761 atgccctcaa gtaccaatcg ccttataatg cttttgatga catagaactc atacatcatt
     5821 ccttacctag ctatgatttg tctgatattg atctcagtac tcattttgcc gggcaagact
     5881 tcgactttcc cttttacatc aatgccatga caggaggaag tcaaaaaggc aaagctgtca
     5941 atgaaaaatt ggccaaagta gcagcagcaa cagggattgt catggtgaca gggtcttata
     6001 gcgctgcttt aaaaaatcct aacgacgatt cctatcgttt acatgaggtg gcagataact
     6061 tgaaactagc cacgaatatt ggtctagata aacctgtggc gctaggacaa caaacggttc
     6121 aagaaatgca gcccctcttt ttacaggttc atgtgaatgt gatgcaagag ttgctgatgc
     6181 cagagggtga gcgcgtcttt catacctgga aaaaacacct tgctgaatac gctagtcaaa
     6241 taccagttcc tgtcattctc aaagaagttg gttttggcat ggatgtcaat agtatcaagc
     6301 tagcacatga cctaggcatt caaacctttg atatttcagg aagaggaggg acctcatttg
     6361 cctatattga aaatcaaaga ggaggagacc gctcttactt aaacgattgg ggacaaacca
     6421 ccgttcagtg cttgctaaat gcacaaggac tgatggacca agtggaaatc ttagcttcgg
     6481 gtggtgtcag acaccccttg gacatgatta aatgtttcgt cctaggagca cgtgcagtgg
     6541 gactctcacg caccgtttta gaattggtcg aaaaataccc aaccgagcgt gtgattgcta
     6601 tcgttaacgg ctggaaagaa gaattaaaaa tcattatgtg tgctcttgac tgtaaaacta
     6661 ttaaagaatt aaagggagtc gactacttac tatatggacg cttgcagcag gtcaattagg
     6721 cttcatcacc tctacaatag tgtcacctac tacaaagatg atagagcttt tttagaacat
     6781 aatataaaat atttataaat acctcatcaa actcaaaata gagtagatga gtaaatagag
     6841 tatgttatgg agactatttc taagacttgt atgtatagaa acaaagatta aacacccatg
     6901 taaacaattg gtttacatgg gtgattgcct tatattagtt gtttaaatct aagactgtct
     6961 tagctgagat aagtaaaaat gtgctttttc tagatttatt ggtttatcag ctagtaaagc
     7021 attaactaaa ggagcaattt cgtcttgggt tgcccccgcc aaaagagcta atgatttcgc
     7081 atgtagtttc atgtgaccag cttggatgcc agatgaggtc agagctttta gtgcagcaaa
     7141 gttttgagct aaccccacag atgcaatcaa ttgggctaat gttttggcat caggttgatt
     7201 aagaagatca tgtgcgatag aaacagtagg gttaagcccg atagatcccc ccttactagc
     7261 aataggcata gggagggtca tttggccaag cagaacttgt ttatcttggt caaaatgcca
     7321 ctgactaagt ccttgatagc taccatttct tgaggcataa gcatgggccc ctgcttcaat
     7381 agcacgccag tcatttcctg tggctattac cactgcatca atgccattaa aaataccttt
     7441 attatgagta gtagcccggt aaggatctac ttgagctagt cggctggcta gctctatttt
     7501 ttgagctaac tgtagggatt ttgttttatc gtgatctaaa aggcgcacgg gaatctcaca
     7561 actagtagta acaagcgact ctgttgcgta attagataaa atcgccatta gacaatgccc
     7621 cttagacagt cttgttaaat caggaacaag agcttccatc atagtattga ccatatttgc
     7681 tcccatagct tcttgggtat caacagtcag atagaaaatc aaaaattctc ctttttcttc
     7741 caaatgaatg gttctagcgc ctccacctct tttaacaatg gaaggataag ctttatttgc
     7801 caatgcaatt agcttttttg ttttatgaag gatggcggct ttagcgttat ctatttggtc
     7861 gatatcgtaa agaacaattt gaccaatcat ttgtcggttt agggtttgag ctttaaaacc
     7921 acctgagcgt ttgattagtt ttgctgcgaa agatgctgca gcaacaacag aaggttcttc
     7981 cgtgacaaaa ggcatctgat aagttgaacc gttgacaaga aaatcaggag ctatgctaaa
     8041 gggcaaagcc aatcgtccta agacattttc agtcatttga ttagctgttt ggataggcaa
     8101 aagaacgtct gttttgagtt gatttaagtt ttcagcatta agtagtttaa atttttcgat
     8161 aagttggagg cgttcttcga atgttttctt tgaaaaaccg ctccagttaa gattagtttt
     8221 tgtcattggt atgatagatc ctttgatgct ccttgatggc tgttagagca aattttccag
     8281 ttaagtaaat gtcaaaattg gcattaccat tatcatctaa ttggacttgt tcgtagaaaa
     8341 ggtcttcgta tttagaaacg gaaagacgtg ttcgttgatc tagtaaagct tgtcgattag
     8401 tcattaacat tttatcgtac ccagcaacta actgaccgga ataaaattca cttacggcac
     8461 cggaaccata gctaaaaaaa ccaattttat ctccagattg taatacttta ctattttcaa
     8521 gtaaagataa caatcctaga taaagtgagc cagtataaat atttccaatt tgtttgctat
     8581 aagtaataga agcttgaaag gcttctatta gtttttccct gtgttcagga ggtactgtgt
     8641 tattcataat gttatttaga ccttttaggg ctaacttggg aaatggaata tggaaacaaa
     8701 ctgcagcaaa atcagataac tgaaggtttt ctcttttctg ataagcttgc cacgtggttt
     8761 ctaagcaatt gagatattgc ttggtagagt aaataccatc aacataaggt gtgaaactat
     8821 agttaggcct ccaaaagtcc ataatatccc tagtttgagc cacattatct tcatttagag
     8881 caagaatacg agggtcagca gttaccaaaa gagcaatact accagatcct tgagttgatt
     8941 cgccaggaga tcctacaccg tatctagcaa tatcactagc aataacaagg acacgagaat
     9001 ctggcttaga agccacatgc agtttagcat agtctagagc agcagttgcg ctatagcagg
     9061 cttgttttac ttcaaaggaa cgtgcaaaag gctggatacc aactaagtga tgtacataga
     9121 tagctgatgc ctttgactga tcagtactcg attcagttgc caaaataacc atatcaatct
     9181 tagctcgatc ttcgtcggtt aagatttgat ctgctgcaga agcagctaaa gtaataatgt
     9241 cttcagtgat tggtgccaca ctaaaagatt caatgagtag cccttgacta aattttgctg
     9301 gatccacttg gcgtacaagc gctaaatctt ccaatttcaa gacatattga ctggttgcaa
     9361 aaccaatctt atcaattcca attgtcatat ttgtccttct tttagttatt tttatagtct
     9421 tacccattct atcacatttt actgcaaaat tagactgata aagttatttg ttttatcctt
     9481 taatagttaa aatgttcatg accacatgaa gtttttcgaa tgtttattta ttctggtatt
     9541 ttttggtaaa attagttaga atagtatgaa gtatgcttac agaaaggtta ttagagatga
     9601 caaaagctga ccagattttt aaagctaata ttcaaaaaat tataaatgaa ggatcattga
     9661 gtgagcaagc acgtcctaaa tataaagatg gtcgaacagc tcattctaag tatattactg
     9721 gggcgtttgc tgaatatgat ttagctaaag gagagtttcc catcacaact ttacgaccca
     9781 ttccaattaa atctgctata aaggaattat tttggatata tcaagatcag tctaacagtt
     9841 tagatgtgct agaagctaaa tataatgttc attattggaa tgaatgggaa gttgaccaga
     9901 cacgtactat tgggcaacgt tatggtgctg tagtcaaaaa acatgatatc atctcaaaaa
     9961 tactaaagca attagcagaa aatccttgga atcgtcgtaa tgtcatttct ctctgggact
    10021 atgaagcatt tgaggagaca aaagggttgt tgccatgtgc ctttcaaatc atgtttgatg
    10081 ttagacgtgt aggggaagat ctttatttag atgctagttt gacgcaacgt tctaatgaca
    10141 tattagttgc tcatcacatc aatgccatgc aatacgttgc cttgcagatg atgattgcta
    10201 aacattttgg atggaaaata ggtaagttct tttattttgt taacaattta catatttatg
    10261 acaaccaatt tgatcaggct caagaattac taaaacgaca gccagttgcc agtcagccta
    10321 agcttgtttt aaatgttcca gatgggacta atttctttga tattaaacca gatgattttg
    10381 aattacaaaa ttatgatcca gtgaagcctc agttgcactt tgaccttgct atttaaactt
    10441 tatttagatt ttttgtgagc attttgttca taaatttggt aaaataaata gagtttaaaa
    10501 tgaaggaaat aattaatgac aaaggaaatt attgctattt gggcagagga tgaagcaggg
    10561 cttattggtg ttgcgggtaa gttaccatgg tatttaccaa aagagttaga acattttaaa
    10621 aagacaacgc tacatcaagc aatcttaatg ggccgtatga cttttgaagg aatgaattgc
    10681 aaaagacttc ctcaacgtca aacccttgtc atgacaagaa atagagatta tcaagtagat
    10741 gaggtgttga caatgactag tattgaaaaa gtcttggagt ggtaccatgc gcaggataaa
    10801 acactttata tcattggtgg gaataaggtt ttagaagcgt ttaatggtta tttcgatcgt
    10861 atcataaaaa cagttatcca tcatcgtttt aaaggagata cctaccgacc aaatctagat
    10921 tttagtcatt tcacgcaaga aagccaaacg ttctatgctc gagacgctaa aaatctttat
    10981 gattttaccg ttactgcttt aaaacacaaa tagtctgagg agatgataag cgatgcaacg
    11041 tagtattttt ggagtattta cggctttttt gtgcgtgatt tgtgttcttt gtgccatccc
    11101 agcttttaaa aagaatcgtt atggcttagg aagtctgttc ttattaaatg cgtttactaa
    11161 tctggttaat agtattcacg ccttctatgg tacattgttt tgagatgtga cttgcaaaga
    11221 cagcactggt gaagatttag ctatcaagca agaatcacca aaaaccaata caacacattg
    11281 actaatatta aaattcagta aaagataaga gaaagtaaga gaattataag aaatggcagg
    11341 aagtagaact aacgatatta aagtatactg ttcattttgt ggtaaaagtc aggatgacgt
    11401 taaaaaaatt atcgcaggaa ataatgtttt catctgcaat gaatgcgtag ctttatcaca
    11461 agaaattata aaagaagaat tggctgaaga agtccttgcc gatttgacag aagttccaaa
    11521 accaaaagag ctccttgatg ttttaaatca atatgtggtt ggtcaagatc gtgctaaacg
    11581 tgctttatca gttgctgtgt acaatcatta taagcgtgtt tcgtttacag aaagtcgtga
    11641 tgacgatgat gtggatttac aaaagtccaa cattttgatg attggaccaa caggttcagg
    11701 aaaaaccttc ttagcacaaa ctctggctaa aagcctcaat gtaccatttg ctattgcaga
    11761 tgcaacttct ttgactgaag cagggtatgt tggagaagat gtggaaaata ttttactcaa
    11821 actgattcag gctgctgact ataatgtcga acgagcagag cgtggtatta tttatgttga
    11881 tgaaatagat aagattgcta aaaaaggtga gaacgtatct atcacacgtg atgtatctgg
    11941 tgaaggtgta cagcaagccc ttcttaaaat tattgaaggt acggtagcaa gtgttccccc
    12001 acaaggtggg cggaagcacc ctaatcaaga aatgatccaa attgatacaa aaaatatctt
    12061 gtttattgtt ggcggggctt ttgatggcat cgaggagatt gttaaacaac gtttaggtga
    12121 aaaagttatt ggttttggtc aaaacagccg taaaattgat gacaatgctt cttatatgca
    12181 agaaattatt tcagaagata ttcaaaagtt tgggcttatt ccagaattta ttggccgctt
    12241 accagttgtg gcagcccttg aacaactaaa cacatcagat ttgattaaaa ttttgacaga
    12301 accaagaaat gccctggtca agcaatatca ggcccttctt tcttacgatg gcgtcgaatt
    12361 ggcatttgat aaggaagcct tagaagccat tgccaataaa gccattgaac gtaagacagg
    12421 agcacgtggt cttcgttcta ttattgaaga aacgatgtta gacattatgt ttgaaattcc
    12481 aagccaagaa gatgtcacaa aagtgcgtat caccaaggct gctgtcgaag gcaagtcaaa
    12541 acccgtttta gagacagctt aaggagaaat aatggctgaa gaacaagtct taaataccca
    12601 taacgcctca attttattga gtgctgccaa taaatctcat tacccccaag atgatttgcc
    12661 agaaattgcc ctcgctggac gttcaaatgt tggtaaatca agttttatta ataccatatt
    12721 ggggcgcaaa aatttggcaa gaacctcaag caagccagga aaaacccaac tattaaattt
    12781 tttcaatatt gatgacaagc ttagatttgt ggatgtccct ggttatggct atgccaaggt
    12841 ttctaaaagt gaacgggcca aatggggaaa gatgatcgaa gaatacttaa ccaccagaga
    12901 taatctgcgt gctgtcgtga gtttggttga tttacgtcat gccccttcaa aagaagatat
    12961 tcagatgtat gactttttga agtactatga cattcctgtt attgttgtgg caaccaaagc
    13021 agataagatt cctcgtggca aatggaacaa acatgagtct gtggtcaaga aagctttgaa
    13081 ttttgacaaa tctgatactt ttatagtatt ttcttcggta gaacgtattg gtatcgatga
    13141 ttcttgggat gctattttag agcaggtcta gcgataggtg ttgatttatc tatgctaaaa
    13201 cattctcagt agagggtgtt tttcttatcg aaaacataaa aaatcatagt taggtttacc
    13261 gattttactt gacgccttaa tgatgacatg ctagtatttt atattaagga gatgagtcat
    13321 gacacaagta gcccaagggc gctctaaagg aaagtcattg ttatgccatc aatgcaatgc
    13381 cctttttgta tttattattt ttcttatctt gcttgctgta ctttttggtg ttcgatatcg
    13441 taatagctct attgaaggta tctggcgaac aacaagcatt gatcagaagt taggcgatga
    13501 ttttgctaaa cgtcttactg gtttgcatca gagccctctt attgatgata gtttattaac
    13561 gtcatctcag atgatactaa cagttaaaaa taacaacgtt gacttgagtt ttagtgttca
    13621 agttgaacga gacatttttg tcaaacgttt agctgcttat caccaaaatg aattattaaa
    13681 gacattaaag gaaaatcatt tagttgttgg tgacttgagt agtaaagaac gccaaattat
    13741 tgagaatagt atgccagcta gccatgaatt agaaatgatt ttagatcaag cttttgagaa
    13801 attagcttct cagatcggag gcaaatataa tcaaaaaaca ggacatttat ctgctgttgt
    13861 tctcaaagga aaagttaatc gtattttgca caccattgat atcaaagaag aagtagcagc
    13921 gggacatact tctttttcaa aaggattgct cacacctaat ggttattttg attacaccag
    13981 atttggaaag aaacttgagt tattaggcga tgaaaaaatt atttttaaaa aagcgctaaa
    14041 aaaaagtccg tcaagtgtat aacgtagtca caagacggat tttttcatgt tttgaaaatt
    14101 attcaattga agaagtttat tactgatctt tttgcttaat cactagttgt ccttctttta
    14161 ggattgcctg aagttttttg acttctggat ggtcaagata ataatcagtt atacggtcac
    14221 gaatttcctg ttcgataata cgtcgtaatg gacgagctcc catagcgtga ttgtacccta
    14281 aatctatcaa atgagcttta gcgtcatcag caatcgttaa actaatacct ttttttgcgg
    14341 tggtttgatt tacttcagct agcattaaat caacaatttc ttctaaattt tctttttgca
    14401 gatgattaaa tttaatgata ctattaaaac ggttcaaaaa ctctggtctg aaataaggtg
    14461 caatgcgatc cataatgtta gacccagaag tttccgtatc ttgttggcca aaaccggcat
    14521 ttgatgtagc aataataacg gtatttttaa agttaatagt atttccttgt ccatctgtca
    14581 atcgtccatc atctaacact tgtagaagaa gtgtaatgat ttgaggatca gctttttcaa
    14641 tttcatctag taagacaata gcataagggt tacgacgaac acgctcagtt agggtattat
    14701 tattatcatc gtagccaaca taaccagccg ttgtcccaat caattttgac acagcagtgc
    14761 gatcgttata ttcggacata tcaagtcgaa taatagcatc tttggaacca aataaatcaa
    14821 gtgctaattg tttagctaac tctgttttac caacaccagt tggacccaca aaaaggaaag
    14881 aacctattgg acggttacca tcatcaaaac ctgctcgatt tcgtcgaata gcacgtgcta
    14941 ctgctgcaac agcctcatct tgtccgatga catggctttt taagcggctg ctaattcctt
    15001 tgagcctttc taaatcatta gtccccatgt tagagacggg aataccagtt aagcgctcta
    15061 cagactctgc gatatcattg actgtagcag taacattttg gctttggtta tgttgctcaa
    15121 tttgcttttg taatgtttca atccgtgttt ttgctgctaa agctttttca aagtcttctt
    15181 tggcgacagc tttttcttga ctctcttttt gtttagctat ttcagtttcg agtgttttta
    15241 agtcagtgac cgggtgttgc gcagctaaat gagcagctgt catatccagt aagtcaattg
    15301 ctttatctgg caggctacgc tgtgggatgt attgaataga ataatcaaca gcagctttta
    15361 gaacattatc aggaagggta atatggtggt gttgttcata aagattacga atacccatta
    15421 aaatgtgaaa agtatcttca gctgatggtg cattcacttt aacttcatta aagcgacgag
    15481 caagagcagc attttttaaa atagtattgc ggtattcgtc ttgagtagta gcaccaatca
    15541 gtgttaattc tcctcgtgac aaggctggtt taagaatatc tgcaagtccc tttgagcctg
    15601 aatcactgct tgtggcacca gcaccaacta tttgatgaat ttcatcaaaa aataagatga
    15661 tattcccagc ttcttttact tcttgaatca agttttgaat ggtctcttca aaggaaccac
    15721 gatactgtgt accagcttca agactagaaa tatcaattga tacgatttcc ttgtttttaa
    15781 tagcagctgg gacatctcca ttaacaatgg cttgagctaa accttcaatg actgcagttt
    15841 taccgacacc agcatctccg acaaggacag gattattttt agttcgtcgt gccaagattt
    15901 cagcggtatc ttgaatttct ttgttacgac caatgacggg gtcaagatgc ccttgacgag
    15961 cttcttgtgt taagttagtt ccgagttgag tcaatacact atcagcttta ggtgttaaca
    16021 tttgagaatt tgttgctttg gttgtcgcta cagggagttg tcctgtttga cgatagtgtt
    16081 ggaattcttc gggagttatt tcgcgaccgt taacgagata gcggggattt tcgctacgat
    16141 aaccacccat gtttgccatt aattggttga aaatatcatc catatttaca aaaggatctt
    16201 taccagaaaa atgtgtcata tcagttacct cgcaataaaa aatagactat aagatgtttg
    16261 taagcagtcg cagaatcgtt gttaggattt cacatgatag gaaacccttt gctaataaaa
    16321 tgattcagac attattttta ctcatcttat agtattatta taatcaaaag gtcagtaaag
    16381 gtcaaacaaa aacacttgat tttcaaaaag ctaaataaac acgaaaagta agtgcttata
    16441 tgatgacttt agaataaatc ataagtttta aaaagatcat cctattctat agcacttaga
    16501 ctgtcaatga gagaaaaaca aatgttttca ttaacaagtt ggcgctttca tggtataata
    16561 aagtgctaag acgcaattct attataaggg ggaatcatgg aagcactcaa aaaaattgcc
    16621 ggtgttaccg ctgcgcaata tgtgactgat ggcatgacca ttgggcttgg aactgggtca
    16681 acggcttact attttgttga ggaaattggt cgtcgcgtaa agcaagaagg actgcaagtg
    16741 gttggtgtga ccacgtcaag tgtgactagc aagcaagcag aaggcttagg cattccttta
    16801 aaatcgatag atgatattga tagcattgac ctcaccgtag atggtgctga tgaagtggat
    16861 aaggatttca atggaatcaa gggtggtggc gcagccttac taatggaaaa aattgttgca
    16921 acaccaacaa aagaatacat ctgggttgtt gatgcttcta aaatggtaga gcatctgggt
    16981 gcctttaaat taccagtcga agtcgttcaa tatggtgctg atcgtttgtt ccgtgtcttt
    17041 gaaaaagctg gttacaaacc gtcttttcgt atgaaaggtg atagtcgttt ggtgacagac
    17101 atgcaaaact atattattga tcttgatttg ggttgtatta aagatcctgt tgcttttggt
    17161 cacctgctag atggaacagt tggtgttgtg gaacacggtc tctttaatgg tatggttgat
    17221 aaggtgattg ttgctagtaa agacggcgtt actgttttag aagcgcctac agcaggctag
    17281 tcttagcata taacagcgtt aatatatttt ataggtattg gggagtcaac cgtaacctcc
    17341 cctagattgg agacttatgt caaaatttaa tcgtattcac ttggttgttt tagactctgt
    17401 cggtattggt gcagcaccag atgctgacaa attctttaat gctggtgtag ctgatacaga
    17461 ttctgacact ctcggtcata tttcagaagc agcaggctta tcggttccaa atatggcaaa
    17521 aattggactt ggaaacattt ctcgtccaat accactaaaa actgttccaa cagaagacaa
    17581 tcctactggt tacgtgacca aattggaaga agtatctctt ggaaaagata ccatgacagg
    17641 ccattgggaa attatgggct tgaacattac ggaacctttt gacactttct ggaatggttt
    17701 cccagaagag attttaacta agattgaaga attctcaggc cgcaaaatca ttcgcgaggc
    17761 caacaaacct tattcaggaa ctgcggttat tgatgatttt ggtccgcgtc aaatggaaac
    17821 aggtgagttg attgtttaca cctcagcaga cccagtgctt caaattgcag cccatgaaga
    17881 cattattcct gtggaagagc tttacaagat ttgtgaatat gctcgctcca tcacgcttga
    17941 acgccctgcc cttttaggcc gtattattgc gcgtccttat gtaggcgaac caggaaactt
    18001 tacacgtacg gctaaccgtc atgactatgc agtgtctcct ttccaagata ccgttttgaa
    18061 caaactggct gacgcaggtg tcccaactta tgccgttggt aagattaatg acatctttaa
    18121 tggttcaggt attacaaacg acatgggaca caataagtcg aacagccatg gtattgacac
    18181 gcttattaag actcttcaat tacctgagtt tactaaggga ttctccttta ctaacctcgt
    18241 tgattttgat gccaactttg gtcatcgtcg tgacccagag ggttatcgcg actgcttgca
    18301 tgaatttgac aatcgcctac ctgaaatcat cgcaaatatg aaagaagacg atttgcttct
    18361 catcactgct gaccatggta atgacccaac ctatgcaggc accgaccaca ctcgtgaata
    18421 cattccattg cttgcctact ctgcatcctt tactggaaat ggtcttattc cacaagggca
    18481 ttttgcagat atttcagcga ctgttgcaga aaattttgga gttgatacag ccatgattgg
    18541 ggagtcattc cttggtcact taaaataaga aagttagtaa ttgataatgg aagaaatcac
    18601 gatttatcat aatccaaact gtggcacttc acgtaatgtt cttgccatga ttcgccatgc
    18661 aggtattgag cctactatta ttgagtactt gcagacgcca cctaatcggg agactttaat
    18721 tgagctctta caatcgatgg gaatctctgc gcgagaactc ttgcgaacca atgttcctga
    18781 atttgaggct catggattag caaatcaagc agtagctgag aaagacgtta ttaatgccat
    18841 gttgacggat ccaattttga tcaatcgtcc tattgttgtg actcgcaaag gagtaaaact
    18901 ttgccgtcct tctgagacct tactggatat tcttcctgtt cccctgccta gtccttatat
    18961 gaaagaggat ggcgagagtg tgaaccctat tgaggtaaaa ggagaaaaag atgtcattga
    19021 tgactaaaat taacgaaaca aaagactttt tagttactaa aggaattgaa actcccgaat
    19081 ttggattaat tctgggttca ggccttggtg aacttgctga agaagtagaa aatgctattg
    19141 ttattgatta tgcagatatt ccaaactggg gtaaatcaac agttgttggc catgctggaa
    19201 agttagttta cggtgattta gctggtcgta aagtacttgc cctacaaggt cgtttccatt
    19261 tttacgaagg aaacccgctt gaagtggtga ctttccctgt tcgtgtcatg aaagctctgg
    19321 gatgtgaagg cgttcttgtc acaaatgcag ctggtggtat cggctacggc ccaggtacct
    19381 tgatggcaat cacagaccat atcaatatga ccggaaataa cccactaatc ggtgaaaact
    19441 tggacgagtt tggtccacgc ttccctgata tgtctgatgc ctatactaag gtttatcgca
    19501 ataaggcaca tgaagtggct gaaaaaatga acatcaaact agaagatggt gtttatatgg
    19561 gcttaactgg tccaacttat gaaacaccag cagaaatccg tgctttcaaa gtattaggag
    19621 cagatgctgt tggcatgtca actgtaccag aagttattgt ggctgctcat tctggactta
    19681 aagtacttgg tatttcagct attacaaact ttgcagctgg ttttcaatca gaattgaacc
    19741 atgaagaagt tgtggaagtg acccaacata tcaaagaaga tttcaaaggt cttgttaaag
    19801 ctattttatc ggagttgtag gacgaacaaa atcaactgga gcattattac aggaatgtta
    19861 ttttatgtcg tcagtttggc acatctgttc gcaataaaaa aatcaaaaaa taatcacgga
    19921 gtgtgagttc catgaatgtt gaactcagat tctagctttt ctaactaaca taaccaacga
    19981 agggaaagag acgtattcgg tttaaattga gtatggactc gaacatttct tcgtattaat
    20041 ttttaaataa taaaggaaag agagttagtc ctttcttatt tgaactcgat ttttagctct
    20101 cttctattca atatcaatta tgaaaggaat ggggttgtat tcaattgaat acgggcggaa
    20161 agctcggaaa ctagataaac taacttttga gctcacacat ggcgttagtt ccctaaattt
    20221 cagtcgcttt ctgtccgccc tctgaccttc tacaaaataa aaggaaaggt agggctaact
    20281 gtattcattg aattgaatac gggcggagaa ctgtttttct tccttataaa aaataaaaaa
    20341 ataagaaagg tgagggctga gttcattaat ttgaattcgg gctaaggact tggtcaaaaa
    20401 gataagttgt ctagaaaatc aggattttct gccaacttcc tattttgcca tcgttctttt
    20461 aatgccctca gtatcataat ttatgtctat ccatatttct gccaaaaaag gcgatattgc
    20521 tgataaaatt cttctacctg gagacccttt gcgcgcgaaa tttatcgctg aaaatttcct
    20581 agaagatgca gtgtgtttta acgaagtgcg taacatgttt ggctacacag gaacttacaa
    20641 agggcaccgc gtttctgtca tgggaactgg tatgggaatg ccttcgatct ctatctatgc
    20701 tcgtgaatta atcgttgatt acggtgtcaa aacattgatc cgtgttggta ctgcgggtgc
    20761 gattgaccca gaagttcatg tgcgtgaatt ggtgcttgcc caagcagcag caaccaactc
    20821 aaatattatc cgtaatgact ttccagaatt tgatttccca caaattgctg attttggttt
    20881 acttgacaag gcttaccata tcgccagaga aatgggagta acaactcacg ttgggaatgt
    20941 gctttcttct gatgtctttt acactaacat gcctgagcgt aatatggctc ttggtaaatt
    21001 gggtgttaaa gccatcgaaa tggaagcagc agctctttac tatttagctg ctcagcacca
    21061 tgtcaaagcc cttggaatca tgacgatctc agataacttg aatgatccaa ccgaagatac
    21121 tacagctgaa gagcgccaaa ccactttcac tgatatgatg aaggtcggct tggaaacctt
    21181 aattgccaat gactaataat caaacactag acatcctttt ggatgtctat gcttataatc
    21241 acgcctttag aattgctaaa gccttgccaa atatccctaa aactgccctc tatttactag
    21301 agatgttaaa agagcgcaga gaattgaacc ttgcctttct ggcggaacat gcagcagaga
    21361 atcggaccat tgaagaccag taccactgtt cattatggct taaccaatcg cttgaagatg
    21421 agcagattgc caattacatt ttggatttag aagttaaagt aaaaaacggt gctattattg
    21481 atttcgtcag gtcagtgtcg cctattcttt accgactttt tctcagacta atcacgtcag
    21541 aaattccaaa cttcaaggct tatatttttg atacaaagaa tgaccaatat gatacctggc
    21601 attttcaggc catgttggaa tctgatcacg aggttttcaa ggcttacctg tctcaaaagc
    21661 agtctcgcaa tgtgacgacc aaaagcttag cagacatgtt gacgttgacc tccttacctc
    21721 aggaaatcaa ggacttggtt tttttgttac gacattttga aaaggctgtc cgtaatcctc
    21781 tggctcattt gattaagcct tttgatgaag aggaactgca tcgcaccact catttttctt
    21841 ctcaggcttt tttggaaaac attatcacct tggcgacttt ttctggtgta atctaccgac
    21901 gtgagccttt ttactttgat gacatgaatg ccattattaa aaaggagttg agcctttgga
    21961 gacaatctat tgtctgatat ttatcaaaaa acacgataac ttgaccgata caggtcttac
    22021 taccgtgttt ttttagtatg acgattgaaa aagacattaa tcaaaggtta cttcttcgag
    22081 aaggtattcg ataaaacgtt cccccatttt ggacaagttg gctttttcat gcttgataaa
    22141 aacaatgtca atttcgtcag ggacatctag cgggatagcc acaatctggt caccatttag
    22201 attgctattt agaataccac tggcaacggt gtagccatct aaaccaatca ttaagttaaa
    22261 gagggtggca cggtcactga ccacaattga tttgttgtgg ggcatctggg acatcatctc
    22321 ttctgaaaaa taaaaggagt tgtgaatccc ttggtcatag ctcaggtaag gaaaatctct
    22381 caagtcgtcc atgcttaata ggcttttagt tgctagagga tttgatttgc tgacaaaaat
    22441 atgaggctgt gccttaaata atggagaggc agtcaaatga ttgtcatcaa ataatttggt
    22501 caagacatct cggttatagt cgttgataaa gagaacacca atttcagatc gaaagttttt
    22561 gacatcatca atgatttccc aagttcttgt ctcgcgcaaa aagagttcat accgagtcat
    22621 gtcggtccgc ttgaggagtg agacaaatgc attgactacg aaggcataat gttgagatga
    22681 aacgctaaag agctctcggc cagtattgtg gtttttatag cggtcttcta acagtgatgt
    22741 ttgctctata atttggcgag cataagataa aaattccacc ccatcttttg tcaaggtgat
    22801 ccctttagga tttcggttga aaatggtaat gcccatctcc atttccaaat ccttgaccgc
    22861 attggataga cttggttgtg tgataaataa ttgcttagca gcttcattca tagagccgca
    22921 ctcaacaatt ttgataatat aatgcagttg ttgaattctc ataagtacag tctagctcaa
    22981 aaaaaataaa gacgcaagca caaacgtcat catgggttta gaactttgaa aaagcgctgg
    23041 agtcttttct caatatggcc taggataaat atgattcaat tttgagagtt gaatctatca
    23101 atttcattgc ccttttattt ttcttgtgtt atattaatag tattaacaaa taggtattct
    23161 tctaatcaaa gggtggtggt cgtgtgaatg ttactgaaca aaatagtcat caaatcttaa
    23221 tccaaaaatt attggtcagt atccactatt tgactctttt tcgagatgaa ctgaagcttg
    23281 tagaacgaac tccttctata cttggagggg aattttcagc tcatttagta cagtctgagt
    23341 tgggagatat tgttgcggcc attgatacct tggatatgca gcaacgcttg attgagtcta
    23401 ccttttggta tgaagaatca gcttttaagt tgatgaacaa aactttggat attgtcgata
    23461 attggattaa aggagtggat catctgatag atttatgcca gtccaaagaa gtctttcaaa
    23521 ttattattgg agataaacgc attcgagttt ttggggtctt aagtgatgtt ttttcatctt
    23581 taaaagtgag tgctttgtca cttaaggaag ctcctattcc ggatgtgctc tatgaacata
    23641 tccagagggt taatcttgaa gaagaagctt ttataaaata ttaccaaagc cctaaggtac
    23701 ccacaggtga gtttgaataa atgattgggt aaaaatgata aaatgagttg acgtaagtat
    23761 acaaaaaaag atatagtagg aaagatgtgt tcaaataaca aaaagttttg acatcttgtt
    23821 ttaaaaaagc tataatagtt taaatttaga cacctttaag tgagtccaga gaggcaaaca
    23881 aggtatacaa gataaaaaaa gggaattccc ttttagtttg ctgtagcctc gcttctttgg
    23941 tagcgaggct ttttggtgct taatgagata ttgacacatt atagaaagga taagttatga
    24001 aagaagaacg cccaattatt gctttagact tttcatcatt tgaggagact aaagcatttt
    24061 tagacttatt tccagcagaa gaaaagctat acgtgaaaat tggtatggaa ttatattatg
    24121 cgcaaggacc agatattgtt cggtatatca aatcgttagg gcataatgta tttttggatt
    24181 taaaattaca tgatattcca aatactgttc gtgctgctat ggcagttctt aaagaattag
    24241 atattgatat ggcaactgtt catgcagctg gtggtgtaga gatgctaaaa gcagctcgag
    24301 aaggactagg tcaaggccct accttaattg cggtaacgca gctaacttca accagtgaag
    24361 accaaatgcg tggtgatcaa aatattcaaa cgagtctttt agagtctgtt ttgcattaca
    24421 gcaagggggc agctaaagct cagctagatg gggtggtttg ttcggcacaa gaagtagaag
    24481 ctatcaaggc ggtgacacct acgggattta cttgcttaac tcctggcatt cgtcctaaag
    24541 gcagtaatat tggcgatcaa aaacgagtga tgactccaaa ccaagcaaga cgcattggaa
    24601 gtgattatat tgtggtaggg cgaccaatta cccaggcaaa agacccagtg gctgcttacc
    24661 aagccataaa agctgagtgg gcaggctaac agataagatt aggaaaccaa cacttgtctg
    24721 ttaaagaaga aaaaggagaa taagaaatga cactagcaag ccaaattgca actcaattac
    24781 ttgatattaa agctgtttat ttaaagcctg aagatccttt tacgtgggca tctggcatta
    24841 aatcacctat ttacactgat aatcgtgtca ccctttctta tcctaagact cgtgatttaa
    24901 ttgagaatgg gtttgtggaa actatcaggg ctcatttccc agaagttgag gtcatcgctg
    24961 gtacagctac agcaggtatt cctcacggtg ccattatagc agataaaatg actcttcctt
    25021 ttgcttatat tcgcagtaag ccaaaagatc atggagcagg caaccagatt gaggggcgtg
    25081 tgcttaaagg ccaaaaaatg gttatcattg aagatttgat ttcaacaggt ggttcggtac
    25141 taaatgcagc cgcagcagcc agtcgtgagg gagctgacgt tctgggagtt gttgcgattt
    25201 tcacttatga gttaccaaaa gctagtcaga attttaaaga agctggtatc aagttgatta
    25261 cgctttctaa ttatactgag ctaattgcag ttgcaaagtt gcaaggctat attactaatg
    25321 atggtttaca tttacttaaa aaatttaaag aagaccaggt aaactggcaa caataaggaa
    25381 ctatcagcca ggtttatttt taatgaaaaa atctctttaa ccccaattca aaatgttatg
    25441 t
//
LOCUS       DAUGOH010000023        25357 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUGOH010000023 DAUGOH010000000
VERSION     DAUGOH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25357
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.023"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(526..912)
                     /gene="rplQ"
                     /locus_tag="VH957_001076"
     CDS             complement(526..912)
                     /gene="rplQ"
                     /locus_tag="VH957_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEQ8558994.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(927..1865)
                     /locus_tag="VH957_001077"
     CDS             complement(927..1865)
                     /locus_tag="VH957_001077"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEQ8558995.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1911..2294)
                     /gene="rpsK"
                     /locus_tag="VH957_001078"
     CDS             complement(1911..2294)
                     /gene="rpsK"
                     /locus_tag="VH957_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEQ8558996.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2312..2677)
                     /gene="rpsM"
                     /locus_tag="VH957_001079"
     CDS             complement(2312..2677)
                     /gene="rpsM"
                     /locus_tag="VH957_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEQ8558997.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2695..2811)
                     /gene="rpmJ"
                     /locus_tag="VH957_001080"
     CDS             complement(2695..2811)
                     /gene="rpmJ"
                     /locus_tag="VH957_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEQ8558998.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2837..3055)
                     /gene="infA"
                     /locus_tag="VH957_001081"
     CDS             complement(2837..3055)
                     /gene="infA"
                     /locus_tag="VH957_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEQ8558999.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3173..3811)
                     /locus_tag="VH957_001082"
     CDS             complement(3173..3811)
                     /locus_tag="VH957_001082"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEQ8559000.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEELGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3961..5265)
                     /gene="secY"
                     /locus_tag="VH957_001083"
     CDS             complement(3961..5265)
                     /gene="secY"
                     /locus_tag="VH957_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEQ8559001.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5282..5722)
                     /gene="rplO"
                     /locus_tag="VH957_001084"
     CDS             complement(5282..5722)
                     /gene="rplO"
                     /locus_tag="VH957_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEQ8559002.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5937..6119)
                     /gene="rpmD"
                     /locus_tag="VH957_001085"
     CDS             complement(5937..6119)
                     /gene="rpmD"
                     /locus_tag="VH957_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEQ8559003.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6134..6628)
                     /gene="rpsE"
                     /locus_tag="VH957_001086"
     CDS             complement(6134..6628)
                     /gene="rpsE"
                     /locus_tag="VH957_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEQ8559004.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6647..7003)
                     /gene="rplR"
                     /locus_tag="VH957_001087"
     CDS             complement(6647..7003)
                     /gene="rplR"
                     /locus_tag="VH957_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEQ8559005.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7108..7644)
                     /gene="rplF"
                     /locus_tag="VH957_001088"
     CDS             complement(7108..7644)
                     /gene="rplF"
                     /locus_tag="VH957_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEQ8559006.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7847..8245)
                     /gene="rpsH"
                     /locus_tag="VH957_001089"
     CDS             complement(7847..8245)
                     /gene="rpsH"
                     /locus_tag="VH957_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEQ8559007.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8396..8581)
                     /locus_tag="VH957_001090"
     CDS             complement(8396..8581)
                     /locus_tag="VH957_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEQ8559008.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8597..9139)
                     /gene="rplE"
                     /locus_tag="VH957_001091"
     CDS             complement(8597..9139)
                     /gene="rplE"
                     /locus_tag="VH957_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEQ8559009.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9163..9468)
                     /gene="rplX"
                     /locus_tag="VH957_001092"
     CDS             complement(9163..9468)
                     /gene="rplX"
                     /locus_tag="VH957_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEQ8559010.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9547..9915)
                     /gene="rplN"
                     /locus_tag="VH957_001093"
     CDS             complement(9547..9915)
                     /gene="rplN"
                     /locus_tag="VH957_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEQ8559011.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9940..10200)
                     /gene="rpsQ"
                     /locus_tag="VH957_001094"
     CDS             complement(9940..10200)
                     /gene="rpsQ"
                     /locus_tag="VH957_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEQ8559012.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10226..10432)
                     /locus_tag="VH957_001095"
     CDS             complement(10226..10432)
                     /locus_tag="VH957_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEQ8559013.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10442..10855)
                     /gene="rplP"
                     /locus_tag="VH957_001096"
     CDS             complement(10442..10855)
                     /gene="rplP"
                     /locus_tag="VH957_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEQ8559014.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10859..11512)
                     /gene="rpsC"
                     /locus_tag="VH957_001097"
     CDS             complement(10859..11512)
                     /gene="rpsC"
                     /locus_tag="VH957_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEQ8559015.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11525..11869)
                     /gene="rplV"
                     /locus_tag="VH957_001098"
     CDS             complement(11525..11869)
                     /gene="rplV"
                     /locus_tag="VH957_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEQ8559016.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11885..12163)
                     /gene="rpsS"
                     /locus_tag="VH957_001099"
     CDS             complement(11885..12163)
                     /gene="rpsS"
                     /locus_tag="VH957_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEQ8559017.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VH957_001100"
     CDS             complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VH957_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEQ8559018.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13153..13449)
                     /locus_tag="VH957_001101"
     CDS             complement(13153..13449)
                     /locus_tag="VH957_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEQ8559019.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VH957_001102"
     CDS             complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VH957_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEQ8559020.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VH957_001103"
     CDS             complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VH957_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEQ8559021.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VH957_001104"
     CDS             complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VH957_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEQ8559022.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15477..16766)
                     /locus_tag="VH957_001105"
     CDS             complement(15477..16766)
                     /locus_tag="VH957_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEQ8559023.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKLPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VH957_001106"
     CDS             complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VH957_001106"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEQ8559024.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VH957_001107"
                     /gene_synonym="adhC"
     CDS             complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VH957_001107"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEQ8559025.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSTHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIVDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21373..23148)
                     /locus_tag="VH957_001108"
     CDS             complement(21373..23148)
                     /locus_tag="VH957_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEQ8559026.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMIGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGSLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23145..23546)
                     /locus_tag="VH957_001109"
     CDS             complement(23145..23546)
                     /locus_tag="VH957_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559027.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23570..24007)
                     /locus_tag="VH957_001110"
     CDS             complement(23570..24007)
                     /locus_tag="VH957_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEQ8559028.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMNKEY"
     gene            complement(24145..25143)
                     /gene="ruvB"
                     /locus_tag="VH957_001111"
     CDS             complement(24145..25143)
                     /gene="ruvB"
                     /locus_tag="VH957_001111"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEQ8559029.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25190..25285)
                     /locus_tag="VH957_001112"
     CDS             complement(25190..25285)
                     /locus_tag="VH957_001112"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEQ8559030.1"
                     /translation="MLKKYKYYFIFAALLSFKVVQELSAVDWWRL"
BASE COUNT         7491 a         5341 c         4464 g         8061 t
ORIGIN      
        1 aattttgttg gaaacggctt aaagtgacag attttaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt aaaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttgcgat gcaagtattt tttcgaacat ttaaatgaga
      181 ggattacacc gtttatttgc ccatgagagg tctttaaaca cctgcataag gttttcttat
      241 tctaatgacc ttattgtctc tgagaaaact ttataaacgc atcagaagag gcttctgtgt
      301 tattgtttta ctcagcttaa aagcgggagt gtcacctcat aatacaacaa aacgcctgct
      361 tataaaaagt ttctatagct tagatacctt tcataaacaa gcgttacata ttaacaatat
      421 gatgagtgtt cccgctagga aaaatcctag cggtagacca gagctagact aagaataatc
      481 tctcgattac tccatcatca taacactcaa caaaattgat aaaaattaaa ctaattcaat
      541 aattgccatt ggagcagcat ctccacggcg tggttctgtt ttaagaatac gagtgtatcc
      601 accgttacgt tctgcataac gaggtgcaat ttctgagaaa agtttttgaa gagctgtcgt
      661 tgatgtgtat ttatcggtag cttcatcata attttctgat gcgatttcgt tacgaacgta
      721 tgcagctgct tggcgacgag catgaagatc accacgttta ccaagagtaa tcattttttc
      781 aactgtttta cggatttctt ttgcacgtgc ttctgtcgtt acaattgatt cgttgatcaa
      841 aagatctgtc gtcaaatcac gaagcattgc tttacgttgt gagctagtgc gtcctagttt
      901 acggtaagcc attttgtcct cctatattat ttatcgtttt ttagtccgag acctaagtca
      961 gcaagtttaa ccttaacttc ttcaaggctc ttacgtccca gattacggac tttcatcatt
     1021 tcaggctcag atttttctgt taagtcgaag acagtgttaa tgcctgcacg ttttaaacag
     1081 ttatatgagc gtacggataa atcaagctcc tcgatggtgc ggtcaagtac cttttcatcg
     1141 ttcacttttt cagtttcttt cattacttcg gtagcttttg caacctctgt taaatcagta
     1201 aacaggttta agtgttcgat caaaactcga gcagatagac ctaaagcatc ttcaggaata
     1261 attgttccgt ttgtcatgat ttcaatcgtt aatttatcaa agccatcatt gctacctaca
     1321 cgggcaggtt caacttgata attaactttt ttaactggcg tatagattga atctactgcc
     1381 aatgtaccca caggtgcatc atcttttttg ttgccttctg ctggcacata accacgtttt
     1441 ttagcaacag tcattgttgc acgtagagaa tgtccttcag cgattgtaaa aagataatga
     1501 tccgggttaa caagttcgat atcactgtca gtaagaatat caccagctgt tacctctgct
     1561 ggtccttcta cttcaagttc gataatcttt tcgtcttcga cgtatgattt cacagcaagt
     1621 cccttaacat taaggataat ttgcatgaca tcttcacgta cacctgggat tgtatcaaat
     1681 tcgtgtagta ctccatcaat tttaattgat gttactgctg cacctggaag tgaagacaag
     1741 agtacacgac gaagagaatt acctagagtt gttccgtagc cacgttcaag tggttcgatg
     1801 acaaatctac cgtaatcttt attttcatca atttttgtta ttattggttt ttcaaactca
     1861 atcatttttt cacccctcga aacgaaactt gtgtactatt tgttatatga ttatacacga
     1921 cgacgttttg gaggacgagc accattatgt ggcacagggg tcacatcacg aattgcagtt
     1981 acttcaagac ctgcagctgc tagagcacga atagctgatt cacgacctga accaggacct
     2041 tttacagtca cttcaacagt ttttagtccg tgttcttgtg cagattttgc agctgcttct
     2101 gcagccattt gagcagcaaa tggagtagat ttacgagaac ctttgaaacc aagagcacca
     2161 gctgatgacc atgcaagagc attaccatgc acatctgtaa tcataacaat agtgttatta
     2221 aatgtagcgt gaatgtgtgc aacaccagat tcgatgttct ttttcacacg acgtttacgt
     2281 gttggtttag ccaattgttt tacctcctat tttatttttt cttacctgca atcgcaacag
     2341 ctttcccttt acgagtgcga gcattgtttt tagtattttg tccacggaca ggaagtccac
     2401 gacgatgacg gattccacgg tatgaaccga tttccatcaa acgtttaatg ttcatgttta
     2461 cttcacgtcg aaggtcacct tcaactttga ttgcatccac ttcacgacgg atagcatctt
     2521 cttgatctga tgttaaatct ttaacacgga tatcttcaga aatacctgca gctgctaaga
     2581 tttttttaga tgttgcaaga ccaattccgt aaacataagt aagtgaaatt actacgcgtt
     2641 tatcatttgg aatatcaact ccagcaatac gagccatttt ttctcctttc tattttatcc
     2701 ttgacgttgt ttgtgttttg gatttgtcgg acaaattacc ataacacgac cattacggcg
     2761 aataacttta cagtattcgc aaattggttt aaccgatggt cttaccttca tgttttaatc
     2821 cctccaatta tttcgattat ttaaagcggt atgtgatgcg tccacgtgtc aagtcataag
     2881 gactcatttc tactgtaaca cggtcaccta ctaaaatacg aatgtaattt ttgcggattt
     2941 ttcctgatac agttgctaga atttgatgtc cattttccaa ttcaacagta aacattgcat
     3001 ttggcatcgt ttctactact ttgccttcaa tttcaatcac gtcttctttt gccacgcaaa
     3061 agtaccccct aaatttcgat ttgatgtcct ctgagcacag aggtaacaat tataagtcag
     3121 actaaactag tatatcatta ctaatctact tatgcaagta gattagtata atttatttga
     3181 gttctagcaa cgctttttca acatctgcaa aaacgtctgt tatttcttga ttaccttcaa
     3241 tatctgtaac aagaccaagc ttacgatagt gttcaagaat aggttctcct tgagccatat
     3301 tgacgtccaa acgacgttta acagtttcag gcttatcatc ttcacgttga tagtaatctt
     3361 cttctttata atctactggt gggttgaaca ctttatggaa cgtttcacca gttttacgat
     3421 tgataatacg accactcaaa cgctctacaa gacatgatgg atccacttta atattaataa
     3481 caccatctaa gcggagtcct agttcttcaa gtgttgcatc taaggcgtgt gcttgttcaa
     3541 tagtacgtgg atacccatca agcaaaaaac ctttttctgc gatatcatcc tcagctaagc
     3601 gctcttttac aatcccgttt gtgacttcat caggaaccaa ttcaccttta tcaatataac
     3661 ttttagctaa acgtcccatt tcggtttgat tagccattgc ggcgcggaac atatcccctg
     3721 ttgagatgtg agcaacacca agttcttcaa caatcttagc tgcttgggtc cctttaccag
     3781 ctcccggcaa acccatgatt aaaagattca tcttttcctc ctcttttaaa ataaatacat
     3841 agtaggaaat tattttcctt ggtttttgtt ttcaaatggc aacaagaaat cgtttgatga
     3901 taaccaagtc ttattgtcat ttaaaaacaa aatagaaggt tgacaatgtc aacctgtatt
     3961 ctattctgct gtattcataa atccgacata ttttctcttt agaagatacc cctcaagctg
     4021 tttcatacct tcgataccag ttgaaatcaa aatgagcaaa ctagttccac ctaaagcaat
     4081 actagaagaa aggttgagag cttgttgtgc tgctattggc gctaaagaga taaatgctaa
     4141 gaagatagct cctacggttg ctagtttttt tagcaatgcg gacataaatt gttctgtctc
     4201 acgtccaggg cgaacacttg gtatatatga ggaattcttc tgaagatttt ctgctgtctt
     4261 ctcaggatta acttgtacaa aggtatagaa gaatgagaac aatataatca acaaggcgta
     4321 aactatcatt ccgactggag tttgataatt aaaaatttct tgcaaacggt ttaaccacgg
     4381 taaatctcta ccattttgaa caaaaggaat aatcgtactt gggatagttg taatcgagct
     4441 agcaaagata acgggaataa cgccggctgg atttactttt aatggaagat atgaacttgt
     4501 aggtgcacct tgcattagct ttgtgtattg gattggaatt ttatattccg cttgttggac
     4561 atatgttgta aagaaaacaa tagcaagaac agctatgatt aaaatcccaa caatgagata
     4621 agacgagtgt aaatcacttg ccttaacatt tacaaaatag tcttcacgaa ttgttgcaat
     4681 tgcacttgga atagacgaaa taatacccgc aaagataatc attgatacgc cattaccaaa
     4741 tcctttatct gtgatttgtt ctccaagcca ggtaacaata acgctacctg ttgtcagtaa
     4801 tgccccgatc agcaaatatg ttttgatgtc tggtgtctta acaagtgcaa cgttcgacaa
     4861 agtattaaat cctgcagtga taccaatgga ttgggcaaaa gccaaaacaa gtgaaatata
     4921 gcgcgtcgct tgatttaatt tacgacgtcc aacctcacct tgtttgcccc actcaacaaa
     4981 cttaggtaaa atatccatct gcaataactg aacaacgata gaagcagtaa tatatgggct
     5041 aacccccatt gaaaatactg agaaatttct catcgcatta ccactaacta agtttaacat
     5101 atttaagaaa gggagttcac ttaattgctc taagctcttg gcatttacac caggtacggt
     5161 aatatgtgtc ccaattcgga atacaagaat gataaatata gtaaagaaaa ttttattccg
     5221 tacagtcttt atctttaacg cgtcttttag tatttttaag aacataatga gtatcccctc
     5281 attagatgac ttcgattgaa ccacctttag caataatagc tgcttcagca gattttgaga
     5341 acttagctgc ttttacagtc aattttttag tcaattcacc gttaccaagc actttaacac
     5401 ctgatttttc agctcggaca ataccagcat cttttaaaat agccggagtc acttctgtac
     5461 catcatcaaa aacattcagt tgatcaagat tcacaagtgc atattcttta gtattaatat
     5521 ttgtaaagcc acgttttgga atacgacgga acaatggtgt ttgtccacct tcaaaaccta
     5581 aacgtacacc gccaccgcta cgagcttttt gacctttttg accgcgacca gatgttttac
     5641 cattacctga tgatgtccca cgaccaacac ggttacgtac tttacgtgag ccttcagcag
     5701 cttttaattc atgaagtttc attttttctc ctttttttgt aaaatgctag cgcctctatg
     5761 agggaaaagg actccctata gaaactcgcc tatacattaa tgatacttaa gttatccaaa
     5821 ataacttaat acagatacgc actaaccgac tactgtttgt tgccaaaaaa gcaaactaca
     5881 agagtcggtt ttgtgctcgt ttttaattat gaaatcagag atttcacagt tataacttat
     5941 ttaacatctt caacggtaac caagtgagaa atagctgtca ccataccacg gatagcagca
     6001 ttatcttctt tgactactga agagtttaat ttaccaagtc caagagcaac aacagtttta
     6061 cgttgttctg gcttacgtcc gataggagac ttagtcaaag taattttaat ttgagccatg
     6121 atgatcccct ttcttatgct aagtcagaaa ctgagatgcc acgaagtgcg gcaacttctt
     6181 ctgcacgttt aagttgtttc aatccttcaa cagttgcacg aacaatgttg attggagtgt
     6241 ttgaaccaag agattttgaa gtaatatcag caacacctgc taattcgatg acggcacgaa
     6301 ctgcaccacc agcagcaact ccagaacctt ctacagctgg tttcaataat actttagctc
     6361 caccgaagtt agtgtaaact tcgtgaggga ttgttgtacc aaccattggt acttcgatca
     6421 tgtttttctt agcagcttca actgctttac ggatagcttc tggaacttct tgagctttac
     6481 cagtaccaaa tccaacacga ccatttccat caccaacaac tacaagagct gcaaagcgaa
     6541 gacgacgtcc acctttaaca acttttgtaa cgcggttaat cgcaacaacg cgttcttcaa
     6601 gttcaactgc attatcttta aatgccatta ttttgtgtcc tccctattag aatttcaatc
     6661 cgttttcacg agctgcatca gccaaggctt taacacgtcc gtgatagaga tatccaccgc
     6721 ggtcaaacac cacttcagaa atacctttag ccactgcacg ttcagcaaca agtttgccga
     6781 ctacaacggc ttgttctgtt tttgttcctt tagaaacgtc tttatcaaga gttgatgcac
     6841 ttgcgagcgt tacacccgct acgtcatcaa taacttgagc gtagatgcct gtattagaac
     6901 ggaatacgtt caaacgtggg cgatcagcag ttccagagag tttaccgcgg acgcgacggt
     6961 ggcgtttttg gcggattttg tttttatctg gtttcgaaat cacaattttc acctcttaat
     7021 tttaatcaat ttgtctcatt gacaagttgt cgattgaact tatcgagcat gttaaggtgc
     7081 aatacttccc atacccgact aagaacatta tttacctgtt ttaccttctt taaggcgtac
     7141 gtattcacca acgtaacgga tccctttgcc tttgtaaggc tctggtgaac gcaagctacg
     7201 gatgtaagca gctgtttgac caacaacttc tttgttgatt ccttcaactg agattgaagt
     7261 tgggttagca acagtgaaag taattccttc tggagcttca acttcgtctt ggtgagattt
     7321 acctactgaa aggacaagtt tagtaccttg aagttgagca cggtaaccga cacccttcat
     7381 ttcaagatct tttttgaaac cttcagaaac acctacaacc atgttattca agttagcacg
     7441 ggttgtacca tggattgttt tcatttcttt tgagtcgtta ggacgtacaa ctgtgatttc
     7501 agtcccttca actttgattt caatattttt gttaaactca cgagtgagtt cgcctttagg
     7561 gcctttaaca gtaataacat tgttgttatt tgttaattca acgcctgcag gcatagtaat
     7621 tactttatta ccaatacgtg acatgtttat tttctcctgt taaattgtca agccgcatag
     7681 cgactagttt tcacgggggt ttgatagaat gatatacttc aatttatatt tcaaaattga
     7741 acacgagctg tggtctgtgt gaaaaagata aatcttcctt gagtataaac acgctacgtc
     7801 agatttccta ttttcacttt gtccacgacg ctcttagtat cttaaattac caaacgtaag
     7861 cgatcacttc tccaccaaca ttcttttggc gagcttcttt gtcagtcaaa agaccttctg
     7921 atgttgaaat gattgcaatt ccaagtccgt taagaacttt aggcatgtca tcacgttttg
     7981 cgtaaacgcg aagacctggt tttgaaatac gttttaagtt agtgataaca cgctcaccat
     8041 tttttccgta ttttaagaac acacgaatga tgccttgttt atcatcttcg ataacttcaa
     8101 cattttttac aaaaccttca cgtttaagaa tctcagcaat ccctttttta atgtttgaag
     8161 caggtacttc taacacttcg tgttttactt gattagcatt acggatacgt gttaaaaagt
     8221 ctgcaattgg gtcagtcata accatttttt atattctcct cttactagca gtttgatgct
     8281 atcacttact agttaatgtt gtccttaaag gactttggta tcagcttatg ctcacaccgt
     8341 tttaattaag cacaagactt aatctgaaga acaaattaag ttttgtgtca tatttttacc
     8401 aagaagcttt gacaacacct ggaatttgac ctttgtaagc caattcacgg aagcaaacac
     8461 gacaaagttt aaacttgcgg taaactgaat gtgggcgtcc acatttttca cagcgagtat
     8521 aagcttgtgt agagtgtttt gcaggacgtt tgttcttagc aatcatagat tttttagcca
     8581 atttatttac cccctattat tttgcaaaag gcattccaag gcccttaagc aattcacgtg
     8641 attcttcgtc agtatttgca gtagtgacga ttacaatatc aagaccacgt actttatcaa
     8701 catcatcaaa gctgatttct gggaagataa gttgttcttt cacaccgaga gtgtagtttc
     8761 cgcgtccatc aaacgatttt gttggaacgc catggaagtc acgtacacga ggaagtgaaa
     8821 cgctaaccaa tttgtctagg aattcgtaca tacgttcgcc acggagggta acttttgcac
     8881 cgatcgctac accttcacga agacggaagc cagcgattga tttcttagct ttagtaataa
     8941 gtggtttttg acctgagata agtgctaatt cagctgcagc tttctctagg ttttttgcgt
     9001 tggatacagc atcaccaaca cccatattga gaacaatttt ctcaactttt ggcacagcca
     9061 taactgatgt gtaattgaat ttctctgtca acgcaggaat tacttcgtta gtatattttt
     9121 cttttaaacg atttgccatt atgcttctcc tttccttcgt gattaatcaa gcacttcgcc
     9181 tgattttttg ctgtaacgta cttttttacc gtcaacaact ttataaccaa cacgtccagc
     9241 tacaccattt ttatctaata cttgaacatt agagacatgg ataggtgctt ctttttcgac
     9301 gatagctcct tgaggatttt cagtgttagg tttttggtgt tttttaatca ttccaacacc
     9361 ttcaacaata actttgttaa cttttggaag tgctttaaga actacagctt cagtgccttt
     9421 gtccttgcca gcaattacgc gaactttgtc gccttttttt acaaacattc tggtttctcc
     9481 tattatttct tacgccccga tgggcaccct aggaaaacct aggggactac gtttgttaac
     9541 ctgagattaa agtacttctg gtgcaagtga tacgatcttc atgtagccac cctcacgcaa
     9601 ttcgcgtgca actgggccaa agatacgagt tccgcgagga gttttatcat cacggatgat
     9661 tacagcagca ttgtcgtcaa atttgatgta tgaaccgtct ggacggcgtg caccagtttt
     9721 tgtacgaacg ataacagctt taaccacatc acctttttta actgctccac caggagtagc
     9781 ttgttttaca gaagcaacga ttacgtcacc gatgttagcg aatttacgtc ctgaaccacc
     9841 aagtactttg atagtcaaga tctcacgagc accgctatta tcagcaactt tcaagcgagt
     9901 ttcttgttga atcatttcaa ttttctcctt ttagtttgat tagataataa cagctttttc
     9961 cactacttcc acaagacgga aacgttttgt agctgaaagt gggcgagttt ccatgatacg
    10021 aacgatatcg ccttctttag caacgttgtt ttcgtcatgt gctttatatt ttttagaata
    10081 gttgatacgt ttaccataga ctgggtggtt acgtttagtt tcaactacaa ctgtgattgt
    10141 tttgtccatc ttgtcagaca ctacgcgtcc gtaaagagtt ttacgttgat tacgttccat
    10201 ttagaatttc tcctttccca atctattatt tcatttctga ttgcacagtt ttaacacgtg
    10261 caatttgttt cttaacttcg tcaaggcgag cagtcttttc aagttgacct gctgcagctt
    10321 ggaaacgaag atcaaacaat tcttttttga gttcgttttc tttcttagca agttcttctt
    10381 gagacaatcc acgaagctct ttaacaaaat ctttaatttc ttgaagtttc atgtcttctc
    10441 cttattctgc ttcacgtttt acgaatttgc acttaactgg taatttgtgg ctagcaagac
    10501 gtaatgcttc gcgagcaatt tcttcagaaa caccagcaat ttcaaacatc actttaccac
    10561 gtttaactgg tgctacccaa ccttcaggtg cccctttacc agaacccata cgtacaccga
    10621 tagcttttgc agtgtatgat ttgtgtggga agattttaat ccaaacttta ccaccacgtt
    10681 tcatgtaacg agtcatcgca atacgggcag cttcgatttg acggtttgta atccagtggc
    10741 tagttgtggc ttgaagtccg tattcaccga atgaaacttc tttaccacct ttagcctcac
    10801 cgcgcatttt tccacggaat tcacgacggt gtttaacacg tttaggtact aacatttgtt
    10861 atttgcctcc tttagtgttt ttacgagctg gaagaacttc tccacggtaa atccaaactt
    10921 taacgccaag tttaccataa gttgtgtcag cttcttccca agcatagtcg atatcagcgc
    10981 gaagcgtgtg aagtggaaca gttccttctg aataaccttc agcacgagcg atatcagcac
    11041 cgttcaaacg accagaaact tgagttttaa tccctttagc tcctgcacgc attgtacgtt
    11101 ggattgcttg tttttgagca cgacggaaag caacacgttg ctcaagttga cgagcaatgt
    11161 tttcaccaac aaggtgagca tctaaatcag gttgtttgat ttcgatgatg ttgatgtgta
    11221 cttgttttcc agttaatttg ttaagttgac cacgaagagc gtcaacgttt gcgccacctt
    11281 taccgataac catacctggt ttagcagtgt gaagtgaaac aataactttg tttactgcac
    11341 gttcaatttc aatagttgaa actgatgcgt cagctaattc tttattaatg aatttacgga
    11401 ttgcaagatc ttcatgaagg taatccgcgt attctttttc agcataccat ttcgcatccc
    11461 agtcacggat gattccgaca cgcataccaa ttggatgtac tttttgaccc acgattttac
    11521 ctccttattt ttctgataca actacagtta cgtgagttgt acgtttgttg attggtgaag
    11581 ctgaaccttt cgcacgtgga cggaaacgtt tcattgttgg tccttcgtta gcgaatgttt
    11641 cagatactac caagtttgct ttttccaaac caaagttgtt ttctgcgtta gcaattgctg
    11701 agttaagagt tttctcaata acacgagctg ctttgtttgg agtgaatttt aagattgcga
    11761 ttgcgtcagc aactttctta ccacggataa gatcaagtac taaacgtgtt ttacgaggtg
    11821 aaacacgcac tgtacgagcc attgctttag ctgaagtaat ttctgccatt gtgtcctcct
    11881 cctattaacg acgtgttttc ttgtcgtcag ctgcgtgacc tttgtaagta cgcgttggtg
    11941 caaattcacc aagtttgtga cctaccatgt cttcttggat gtaaacaggt acatgtttac
    12001 gtccgtcata aactgcgatt gtatatccga tgaaacttgg gaaaatcgtt gaacgacgtg
    12061 accaagtttt gattactttt ttcttttcgt cgtttgcttg agcttcaact tttttcatca
    12121 aatgctcatc gacgaaaggt ccttttttaa gactacgtcc cattttgtag ttttctcctt
    12181 taaataatgt accacagcgg cttgaattca agagcaagac tccaaactct accgagttgg
    12241 cggaataaat agcaaagcta ttgtaacgct atttcagcaa gttttaagca acttactaag
    12301 attatttttc gttacgacga cgaacgataa gtttgtctga tttagctttc ttgttacgag
    12361 ttttaagacc aagcgctggt ttaccccatg gagttgatgg cgctttacgt ccaactggtg
    12421 ctttaccttc accaccaccg tgtgggtgat cgttagggtt cattacagaa ccacgaactg
    12481 ttgggcggat acctttccaa cggctacgtc ctgccttacc aatgttaaca agtgattgtt
    12541 gttcgttacc aacagtaccg atagttgcac ggcatgtacc aagaatcata cgaacttcgc
    12601 ctgattgaag acgaacaaga acgtatttac cttcttgacc aagtacttga gcagaagctc
    12661 cagctgcacg aacaagttct ccacctttac caggtttcaa ctcaatattg tgaacaactg
    12721 taccgacagg aatgtttgct aatggaagtg cgttaccaac tttgatatct gcatctggac
    12781 cagaaacaat acgttgacct acttcaagac ctttaggtgc aatgatgtaa gctttcacac
    12841 cgtcagtgta atgtacaagt gcgatgtttg cagtacggtt tggatcgtat tcgattgttt
    12901 taacaactgc ttcaacgcca tctttgttac gtttgaagtc gatcaaacgg taatgacgtt
    12961 tgtgtccacc accttggtga cgaactgtga tgcgaccatt gttgttacga ccagctttgc
    13021 tcttaagaga aacaagcaat gatttctcag gcgtgcttgt tgtgatttcc gcgaaatcca
    13081 aagaagtcat gttacgacgg ccatttgtcg ttggtttata aactttaata cccacgttat
    13141 ttcctcctta gattattcag cttcagctgc gaacaactcg attgctttag aatcagctgt
    13201 aagagtgatg atagcttttt tagtttttga agtgaaacct gtgtaacgac caacgcgttt
    13261 tgcttttggt ttaacgttaa cagtgtttac acttgcaact ttaactccgt caaaagcagc
    13321 ttcaacagct tgtttgatca aaagtttgtg tgcacgagta tcaacttcga aagtgtattt
    13381 gcctgcttca agagcaatca ttgacttctc agtgataact ggttttttga ttacgtcgta
    13441 caaattcatt atgcaagaac ctcctcaatt gtagagattg cttctttagt aacaagaagt
    13501 ttgtctgcgt tcacgatatc aagaacactt gcagttgctg cagttgcaac ggttacgttt
    13561 ggaaggttac gtgcagaaag tgctgcaaat tcatttcctt cttcaacaag aacaagtact
    13621 tttgtatcaa tgctaagagc tgaaagcact tttgcaaatt cagcagtttt tggtgctgca
    13681 aatgaaaggc cttctacagc tacaaattta tcttcagcaa cttttgctga gtaaactgat
    13741 ttcaacgcaa ggcgacgaac tttttgtgga agtttgtatc cgtatgaacg gggagttggt
    13801 ccaaagacaa caccaccacc acgccattgt ggtgagcgga tagaaccttg acgagcgcgt
    13861 ccagttcctt tttgacgcca tggtttacgt ccaccacctg atactgctga acggttttta
    13921 accgcatgag taccttggcg aaggctagcg cgttggctaa ttacaacatc aaaaacaact
    13981 gattcgtttg gttcgatacc gaagatagcg tcgtttaatt caactgagct aacttcttta
    14041 ccagtttggt caaatagttt tacgtttgcc attttaactg ttttctcctt tcttattatt
    14101 tagcagcttt aactgctgac ttgatagtga taagagattt cttagcacct ggtacgttac
    14161 ctttaataag gataacgttc ttttctggga taacttgtac aatttcaagg ttttgaactg
    14221 ttacacggtt accacccata cgtcctgcca agcgtttgtt tttgaaaacg cggttaggcg
    14281 caacaggtcc catagaacct gggcgacgat ggtaacgaga accgtgagcc ataggaccac
    14341 gtgattgacc atggcgtttg ataacacctt ggaaaccttt accttttgat gtccctgtga
    14401 cgtcaacaac atcaccagct tcaaattgtt ctacagataa ttctgcacca acttctaagc
    14461 cttcaatgtt tttgaattca cgaatgaagc gcttaggagc tgtgtttgct tttgcaacat
    14521 ggcctttggc aggtttgtta ctcaagactt cacgtttgtc atcaaaacca acctgaactg
    14581 cttcataacc gtctgtttca acagttttaa cttgaagcac aacgtttgga gttgcttcaa
    14641 tgacagtaac agggatgaat tcgcctgatt cagtgaagat ttgagtcatt cccacttttt
    14701 tccctaagat tccttttgtc atgagaaaat atttcctttt cttaataata tttcaaaaag
    14761 ttttttatga gcgttttttg tgctcaaaaa agttttttac gagcgttttt tgtgctcata
    14821 gcaagataca aagagcgtca aactcaaaat aaaaatagaa aatctaacac aaaaacttct
    14881 gtttcgagga agatttatct ttttcatgta gagtttagct cgtgttcaag ttccatcaaa
    14941 cactaactgt acttgcaaaa tctcaccgat taaagtttga tttctacgtt gacaccactt
    15001 ggaagatcaa gtttcatcaa agcatcaaca gttttttgtg ttggattgat gatgtctacc
    15061 aaacgtttgt gtgtacgcat ttcaaattgt tcgcgagaat ctttgtattt gtgagtcgca
    15121 cgaataattg tgtaaagact gcgttcagtt ggaagtggaa ctggtccagc aactgtagca
    15181 cctgtacgtg ttgcagtttc aacgattttt tctgccgctg tatcaagtgt acggtgttcg
    15241 tacgctttca aacggatacg gatttttttg tttgccatct tttctcctct cgtctattta
    15301 cgataatagg ctagctcctc aagaaaaccg acacctgttg cgtggcaatg caaccgagcg
    15361 tgtcgcaacc tcttgcatca ttgctaaagc tgtattttta cagcaccaca atataataac
    15421 agaatcattt agtcattgca agctttttag ggcatttttt caaaaaaact accttcctaa
    15481 tgaaaggtaa tttcttggta ctttttaaat tgtttagaga gaataaacca ccgactggta
    15541 ttatctaaca ctgtcgccat ccagacccct atgagtccat attgccaaac cacaccaatc
    15601 acataaccaa ggccaatgcg aatcacccac attcctatgg ttgttgcata gaaaggaagc
    15661 tttgcttttc ccaaaccctg ccagacggct gtataaacta aagtgcctgc cgttgcggga
    15721 gctcctagta aagaaaatag taaaacaacc atggcggacc tttgagcatc agtattctga
    15781 gtaaatagcg gcaagagact aggacctagc agataggtca aggctcccat aaccagcatc
    15841 atgagggtgg ataaaataaa agcttctcta ataatatacc ttatctcagt caccttaccg
    15901 ccccccagtt gcctggccac tagaataatt gttgccgttg ccatggctaa gccaggcatg
    15961 taattaaact gagtcaaggt ttctccaata gcattacctg ccaaggccgt tgtcccaaag
    16021 cgaacaacaa tgccaataat taggacatct cctgctctca tcatcaaacg ttcaccagca
    16081 gcaggtagtg ataaatcaaa aataattttg tccaaaggtc tcatcaatcg tttcgcaacc
    16141 tgtttaatag gaataaactg acaaagtaaa aacacaccca ctaaacgaga taaaaccgtc
    16201 gcccaagcaa caccaagaag accaaatccc catacataga tagacaaggc agaaaaaatg
    16261 gcattgagta cgtttattaa taagctcact tgcataggaa gcttaggata cccttgagct
    16321 cgaacaatag ctcctaagct agttaaaagt cctagactaa caatcatacc gccgacaatg
    16381 gatagatatt gccctccaac caatgttaca gaagcttcag ctcctagcca ttctaacacc
    16441 tgatgatgtc caacaactga taacaaccct aagccgaccg aaaggaggag tgttacttgc
    16501 aagacacctg ccatatagtt taattgtttg ttctgattat tttctccaat acttcgagca
    16561 atcagactag atacagcagc tcccagcgcg ataaagaggg actgataaat actgataatg
    16621 ttgttagcta tggagacacc agagactgct acaagtccaa tttgagccac caggtaatta
    16681 tcaaccattc ccattaacat ctgtaaaata ttttctatca tagaaggcag agctaaagag
    16741 aaaatttttc ttctattata tatcatttat gtcccctaat aaaaaattct tgatcaaacg
    16801 attttttcaa acacagtcac tggactcatt cagttatttt ggtccattaa tgaattcata
    16861 aagtctatct taatagcaga gtcccaagat acacgacact tagtgctaca gtaacaattg
    16921 accacatgcc aatccttaac atttacctaa cgtttataac taagaagatg aagaacaaaa
    16981 ggactccaaa cgaatttttt ctattatata atatattctt catttagcaa ctttcaatgt
    17041 atcaaaatag cactctcgag tcaaaaatgt tttctgatac tcgagagtgc tattttattt
    17101 ggaatcaagt ttaagcaact taggcttatc tcatatttaa tacatttgta tgtttagctg
    17161 atgaaatcta agaccttgcg cccttggatt aaaccacgtt ccatttcatc aaagacttct
    17221 ggagcagtgt caactggaac tttttcgaca accggagcaa ccagaccttc tgcaccaaag
    17281 gcaaaggctt cttccaagtc tttacgtgtc cctacaagtg atccgaccac tttgatacca
    17341 tctaaaacag tttttacgat agacagttcc atgtattctg atggaagacc tacggctaca
    17401 actgttccac cggcacggac actatcaatt gcttggttaa aagcaacttt agaaacagcc
    17461 gttaccacaa caccatgtgc tccaccggtt ttttcttgaa tatagcctgg aacatcttca
    17521 atttctttgc cgttaactaa aatatctgcg ccaacttctt tagctaactc aagtttatca
    17581 ttattaatgt ccactgcgac aacatgtgca ttaaagactt ttttagcgta ttgaacagcc
    17641 agatttccaa gaccacctgc cccaaagata acaatccatt ggcctggagc agcacctgcc
    17701 tctttaatag ctttataagt tgttacacca gcacaagtaa tggaagaagc ttgagccggg
    17761 tctaaacctt ctggaacttt aactgcataa tcagctgtta ctactgcata ttcactcatt
    17821 cctccatcaa cactgtatcc agcattttta acactacgac aaagtgtctc acgtcctgta
    17881 gtacagtatt cgcaatgacc acatccttca aagaaccatg caatagagac acgatcacca
    17941 acctttaagg atgttacgcc ttctccaatt tcttctacta taccaatacc ttcgtgcccc
    18001 aaaatacgtc ctggtacctg accaaaatcg ccatgtgcaa cgtgtaaatc agtatgacaa
    18061 acgccacagt attctacttt aacaagtgct tcaccatgac caatatttgg aagatcatgc
    18121 tcaacaactt cgacacctgt actagcttga ttaacaacta cggctttcat atcagtcctc
    18181 catctaataa tgactttttt gtaatcggtt acacataaat tgtacatctt ttcacaatga
    18241 aagtcaatag aaacctgaaa agtttctgaa acttaactgg ttaatcttat agctgtttgc
    18301 ctatctgcaa aatacttaac tacattttct gacactggat ataaatgata tatttagaaa
    18361 ataaaatgat ttcttatgac tttaatcata agaaatcatt tcctggtatc aacattaaaa
    18421 atcacttacg tcgtcctgga cgttcagcat aaccatagta agcatcttca ataatttctt
    18481 gcatgtgatc aaccattgga agacgtgggt tagcaggtga acattggtct tcataagcaa
    18541 ggtaagccaa ttcacgagaa tgttctttcc attcattttc gtcgatacct tgagctttga
    18601 agttcatttg aataccaact cggcaaccca gatcataaac agctttcgca taagattcca
    18661 ctgcttcttc tggtgtagaa gctggaagcc ctaacaattt cgcaatgtct tggtattttt
    18721 catccgcacg gtagtaatta tacttaggcc atgtcgccgt tttagctgga cgagttccat
    18781 tatagcggat aacatacggc aaaagaattg catttgtacg tccgtgtacg gtatggaatt
    18841 gtgcgccaat tttatgcgcc attgagtgag aaatacctaa gaatgcattg gcgaaagcca
    18901 tacctgccat agttgacgca ttgtgcatct tttcacgtgc ttcaaaatcg gctgttttaa
    18961 ctgatttttc aagattatca aaaacaattt taatggcttg aagagctaaa ccatccgtaa
    19021 agtcattggc catttgtgac acgtaagctt cggttgcgtg tgtcaaaacg tccataccag
    19081 tatcagcagc aataaagcct ggaacagtca ataccaaagc tgggtcaaca atggctacag
    19141 ttggtgttaa tgagtaatca gcgattggat atttacgatt atttgctttg tcagagataa
    19201 cggcaaatgg tgtcacctct gaacctgttc cagaagttgt tgggatagca acaaattttg
    19261 ttttcttacc aagttctggg aatttgaacg cacgtttgcg gatatccatg aatttttgaa
    19321 cgaggtcatg gaaatcaact tctggttgct cgtagaagag ccacataact ttggctgcat
    19381 ccataggaga tcccccgcca agggcaataa tggtgtctgg tttgaaggta cgcattaatt
    19441 cagtaccttt cataacagtt gtaatgtctg gatctggttc tacttcagca aagatctgat
    19501 aaacaacttt attgcgacga agatcaagtt gttcaatgat acgatccaag aaaccaagct
    19561 caaccatagc gtgatctgta acaatcatga cacgttcaac gtcacgacat ttttgcaaat
    19621 attgaattga atcacgttcg aagtatgttt ttgaaggaac tttaaaccat tgcatattat
    19681 ttctacgtct tcctactttt ttgatgttca agagatttat agcactaacg ttatcaccaa
    19741 ctgcgttacg tccatacgaa ccacaaccaa gagtcaatga tggcaagaaa gcattgtaaa
    19801 catccccgat accaccaaat gtagaaggtg aattccagat gacgcggata gcacggattc
    19861 tagttccaaa ttcttttgcc aactctgcat ctgctgtatg aatggcagct gagtgaccga
    19921 gtccattaaa ttcaaccatt tgacgagctt tttcaacacc gtcttcacgt gattcagatt
    19981 tcaaaacagc aatgactgga gataattttt cacgtgttaa aggctcattt tctgaaactt
    20041 ctttacattc tgcagcaaga atattggttc cttctggaac agtaaatcca gcttgttctg
    20101 caatccaagt agctggtttc ccaacaatgt ttggattcaa tttagcgcca gcacagtttt
    20161 tactgttagc ttttgcacca aaacagaatt cttcaagaag ggctttttct tttttattta
    20221 caaaataagt atggtaagat ttgaactctg caacaaaatc gtcatagatt tctttgtcca
    20281 cgataacagc ttgttcagac gcacagacca taccgttatc aaatgattta gacatcacaa
    20341 tatcatgagc ggcttggcgg atgttagcag atttttcaac ataagctgga acgttaccag
    20401 cacctacccc aagggcaggt ttcccacatg agtatgccgc tttaaccatt gcatttccac
    20461 ctgtcgcaag gatagtggca atgccgtcat gattcatcaa agcatttgtt gcttcaagtg
    20521 atggtgtttc aacccactga acacaatttt caggagcacc agcggcgata gcagcgtctc
    20581 taacaatccg agcggcatgc gttgatgatt cttgtgctga tgggtgaaag gcaaaaataa
    20641 ttggattacg tgtttttaac gagatcaaag atttaaagat agctgttgaa gttgggttag
    20701 ttgttggtgt aatcccacag ataacaccca ccggctcagc aattaatgtc aaacctgtca
    20761 catcatcttc ttcaataatt cctactgttt tttgatggcg catgttatta accacatgct
    20821 cacaagcaaa tagatttttt gttgctttat cttcaaagac accgcgacct gtttcttcat
    20881 aagcatgttt agcaagttca ccgtgagcat ccaaagcagc aacagaagct ttggctacga
    20941 tataatcaac ttgttcttgg tcaagcttac gcatctcttc aagagcagct aaaccttttt
    21001 gaacaagagc atcaattgtc acagaaacag aggttgtttc aacagtatta tgtccttcag
    21061 tcatttgaga ctcctttata ttgttaaaag tttcacaatt ttgtttacaa aattattata
    21121 gcacgttttg aaattttgta aatcatttca caataaattt gtgaagtttt tttcaaatta
    21181 tttctgaaat cctatggtat caatattctt cattaactct ttttcagaaa tatatctaaa
    21241 aaaagccgtt ttgtttctga aaccgctttc ttttaaaaac ctcaaagtac tactatttta
    21301 ccatcatcat ttgttcacaa gaaaaagcca gagcacaatg gatctgactt atctcttaga
    21361 catttcttaa ctttatttag ctggtttttt agctgacttc tcaacagcag tctggattgt
    21421 ggagacatat agttctgctc cttgactatc ttcactataa tgaacaccgt cactgccata
    21481 ccaaatatct ggatgttcaa cagcaacttt ataccagtct gcaatagtga catacttgta
    21541 ttttttggac aatttaagac catagtctct agcttctgca acctgactgg catttttggc
    21601 attatatgga gaaaccaaaa ctaaacgatg tccttttggc aatgcctcaa taaaagactg
    21661 aactgcttga gaatagttgt caagcgagtt aacacctact gctaagacaa cagtcttaga
    21721 tagactctta gacttaattt ggttattaaa taaatcgaaa gcttctttaa aattccgact
    21781 gaccgctgca tccagttgcg cttgtggcat aatttttgag aatgctgcac tagagcgtaa
    21841 tgctacagaa tcaccaataa tacctacgtc actcaaagca ttagcgtctc ctgcagctag
    21901 tgtatgtgtc cgctccatat tactttgagc ctgttgtagg gaactgacca acaattgttt
    21961 ctcaaactta ccaactttag gcgctatcat acaagttcct aaagttaata atgctaaggc
    22021 gagagaccct cctacaatcc acttatagta aggagaacag tcaatttcta aaccaagcag
    22081 gtttggtttt ctcccttgga ccaaaggttc cacaatatag taagacacag tggcaaacaa
    22141 gattgaaaag aaaactgtta gaataactgc caaaatatga gacattaatt ggctaaaaat
    22201 aatgtaaaat ggccaatgga agaggtaaat cccatagcta atatcagcta tataagtgat
    22261 agctttaggc tcttgtacat ctggtgtttg ctcatgaaga acacgcgctg cataaatcat
    22321 aattgatgcg aataagctag ccaaagcaaa gccaaataga taggtcgtga tatggttaaa
    22381 atccaatgtg accgttagca caagcaaaag tgtaaatgct ccaatcatag cagcaaggac
    22441 atactggcgc ggccataaac gtacattttt ttgaaatcga acagtagtct cgttaatacc
    22501 tgttattgtg gcaaacatcg cccctaaaaa gaagggaaaa ctgtgagaaa gactcgaaaa
    22561 ataaatcagg gaaaaatttg aggtcataaa agatcttata aacatgctca agaaactaat
    22621 agcaaatatt cccaaagaaa tcaaaaacag tagtcctctc agttgtttct gagtctcctt
    22681 gcgtctagct aataaccaaa caaatacacc ccacaacaag taaaaatgaa cttcaatagc
    22741 taagctccac gtatgaacaa agagatgtgg aataaattgg ctttcataac tacttcccgt
    22801 caatatttca taaatattag tggtaaatcc taaaacagct gtaatctgac ttcctatatt
    22861 agcaatgaaa tccttcttaa ttaaaaacgt aaaaggaatg gtcaataaaa tcattaacac
    22921 caaaggagga acaattcgat aaaagcgtct ttttaaaaaa ccgataatat cgatagactc
    22981 tttttttgtg tattcatcaa tcaagagggc tgtgattaga tatcctgaaa aggtgaagaa
    23041 aatatcaaca ccaataaaac ctcctggaaa tacattttta aaaaagtggt agagcaaaac
    23101 cagtaaaagt cctgttaccc taacaaacga aaaccatttt attctcattt ttgaaatatc
    23161 ccctgtttaa aaatcccttt atagacttta ttattctttg cttttaacac acctttgcca
    23221 tttgcttgtc ctttatgaaa ctccccgtta tataaccagc ccgtcttagc agtaaaagtt
    23281 ccttttcctt caaataggcc attcttaaaa gtaccctcat agatatcacc gttggggtag
    23341 acaagcttcc cttctccatt cattttatgg ttaatcacgt aaccagtata gtgcatacgc
    23401 cctttatcat aggtcaaact tgtcttattc gaaattctta cgctaaaaac agaaattgca
    23461 caaaccaata tgacaatcac cgagacaatt tccaacttcg cccgtgtaat actccatttt
    23521 tttactatat cttgcatatc tatcatttct tttactcaac ttctaattat caatactctt
    23581 tattcattaa acgagaaagc caatcctggc atccttttct aactaattgg taggtttctt
    23641 caaaatcgtt agtgtaccaa ggatcaggaa cacccccttc tctaaacaga tagattttag
    23701 agtcccattg atgttgcgac atctctttga gatttttcac attatcgcta tccataccaa
    23761 taatatagtc aaaggtgtta aaatcagtta tagttatctg cttggagcat ttagttatat
    23821 cataattaat ttggtaagtt tttaatatgg actgtgtacc tgagtgaata gggtttccat
    23881 gctcccaatc agaagtagca cgactttcta tcatcataac atcacttgat actattgact
    23941 tcattacaaa ctcagccatg gggcttcgac aaatattacc cagacagaca aaacatactt
    24001 ttttcattaa acactccttt gaattattat atcaaatttc taactgatat cggagaaatc
    24061 aatctaataa ttttctgtca acttatcaaa aaatccgaac acaaaaagca ggttcagatt
    24121 aattttctta gatttgaaaa atcattaagt gttttgatag ggatagccaa gatgacgata
    24181 agccttttgc gtcgctacac gacctgttcg tgttcgcatg agaaagcctt tttgaattaa
    24241 gtagggttca tacatctctt caactgtatt acgctcctcg gcaatattca cagataatgt
    24301 ccccaaacca actggtcctc cctgatacat ctcaatcatc gttcgtaaaa ttttttgatc
    24361 aatgtaatcg agaccttcgc ggtcaacatc taacatagtc aaagctctat cagttatttg
    24421 agccgttatg atgccatcac caataatttg agcgtaatca cgcactcgtt ttagtaatcg
    24481 attagcaatg cggggcgttc ctctactgcg acaagctaat ttccgtgcag cttcatggtc
    24541 tatttttatt tcaaaaatag tagctgtacg ctccacaatc tctgtcaaat ccttttcttg
    24601 atagtattcc atgtgaccag tgataccaaa acgagctctg aggggattag ataacatgcc
    24661 tgcacgtgta gtagcaccaa tcaatgtaaa tggaggcaga tccaaatgaa tactacgact
    24721 agtatctcca gcgccaatca taatatcaat atagaagtct tccatagcac tatatagtac
    24781 ttcctcgaca gacattggca tgcggtgaat ttcatcaata aacaaaatat cccctggttc
    24841 taattcattt aaaatagcta ccaaatctcc agctttctca acggcaggac ctgaagtttg
    24901 ctttaaatta actcccaatt cattggcaat cacaaatgcc attgttgttt ttcccagtcc
    24961 tggaggtcca aataataaaa catggtctaa agattcgtca cgtcttttag ctgcttctat
    25021 aaaaatagcg aattgttcct taactttatc ttgtccaata tattcgtgta gatattgagg
    25081 gcgaagagtc cgatccgaaa actcctcatt tcccattaca ttattgtcta aaattctagc
    25141 cataggacta ttataacata aagtaaaaga gagcagtggc ctacttttat tataatcgcc
    25201 accagtcaac agcactaagc tcttgaacta ctttaaaaga tagtagagct gcgaatataa
    25261 aatagtactt atactttttt aacatggata aaaactcctt aataattatt ttttatatta
    25321 ggaattatat cttactatta aatatttaaa aatgaca
//
LOCUS       DAUGOH010000024        24287 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUGOH010000024 DAUGOH010000000
VERSION     DAUGOH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24287
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.024"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            42..247
                     /locus_tag="VH957_001113"
                     /pseudo
     CDS             42..247
                     /locus_tag="VH957_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(318..461)
                     /locus_tag="VH957_001114"
     CDS             complement(318..461)
                     /locus_tag="VH957_001114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559031.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            548..769
                     /locus_tag="VH957_001115"
     CDS             548..769
                     /locus_tag="VH957_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEQ8559032.1"
                     /translation="MNIGFLEHTARNIIREAKRIAIKKFEEAREIDQNAVQLSKSPFD
                     NRRLGIAPKDIVEELVGILLSEESLESEN"
     gene            772..1959
                     /locus_tag="VH957_001116"
                     /pseudo
     CDS             772..1959
                     /locus_tag="VH957_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106750.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            2117..3352
                     /locus_tag="VH957_001117"
     CDS             2117..3352
                     /locus_tag="VH957_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8559033.1"
                     /translation="MIKRWAILFFVVLTCSGLSKIVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDRVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVADSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDNRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVDRTYCRRKILKKGSLVSERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(3468..4430)
                     /locus_tag="VH957_001118"
     CDS             complement(3468..4430)
                     /locus_tag="VH957_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8559034.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEIGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            4763..6040
                     /locus_tag="VH957_001119"
     CDS             4763..6040
                     /locus_tag="VH957_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8559035.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLQDRYP
                     RLTPDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIVDMLVALEQIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRRYWKKHIEKSVLLTH"
     gene            6075..6659
                     /gene="folE"
                     /locus_tag="VH957_001120"
     CDS             6075..6659
                     /gene="folE"
                     /locus_tag="VH957_001120"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEQ8559036.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEHHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKQPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            6668..7468
                     /gene="folP"
                     /locus_tag="VH957_001121"
     CDS             6668..7468
                     /gene="folP"
                     /locus_tag="VH957_001121"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEQ8559037.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESARPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWIDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            7475..7834
                     /gene="folB"
                     /locus_tag="VH957_001122"
     CDS             7475..7834
                     /gene="folB"
                     /locus_tag="VH957_001122"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEQ8559038.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGGKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            7831..8331
                     /gene="folK"
                     /locus_tag="VH957_001123"
     CDS             7831..8331
                     /gene="folK"
                     /locus_tag="VH957_001123"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEQ8559039.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKLLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            8481..9368
                     /gene="murB"
                     /locus_tag="VH957_001124"
     CDS             8481..9368
                     /gene="murB"
                     /locus_tag="VH957_001124"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEQ8559040.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     VYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSVGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            9414..10568
                     /locus_tag="VH957_001125"
     CDS             9414..10568
                     /locus_tag="VH957_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559041.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            10552..11346
                     /locus_tag="VH957_001126"
     CDS             10552..11346
                     /locus_tag="VH957_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559042.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            11343..12119
                     /locus_tag="VH957_001127"
     CDS             11343..12119
                     /locus_tag="VH957_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559043.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            12112..13185
                     /locus_tag="VH957_001128"
     CDS             12112..13185
                     /locus_tag="VH957_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8559044.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKVPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDGIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(13240..13905)
                     /locus_tag="VH957_001129"
     CDS             complement(13240..13905)
                     /locus_tag="VH957_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8559045.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRTQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(13886..15358)
                     /locus_tag="VH957_001130"
     CDS             complement(13886..15358)
                     /locus_tag="VH957_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8559046.1"
                     /translation="MLIVMENRNMTFLSIKNQETHLLTSTGKMLASHQAIKELLLNNQ
                     PNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPNPKNIGKPFQGGDEEAVLAGKKVI
                     STAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTTLNDVALTSKRNYTLSLLLCLLIS
                     LLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLDQIEAAVFVVDKAGILQLCNQAGQ
                     KLIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQLFRYGEEDYLLAISPICVKNDHR
                     GHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHKFMNQLHVIYGLVDIAYYDQLKIY
                     LDSILEPENEILTSLSVLVKEPLLASFLIGEQEKYQELNVHLKIDVLSEIPHSATKNQ
                     LNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHLISHYTLTDNWIDLERVQPIFDLP
                     YFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQHERFNH"
     gene            15320..16036
                     /locus_tag="VH957_001131"
                     /pseudo
     CDS             15320..16036
                     /locus_tag="VH957_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
     gene            complement(16118..17167)
                     /locus_tag="VH957_001132"
     CDS             complement(16118..17167)
                     /locus_tag="VH957_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEQ8559047.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCEDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVNPGDNVCIVGAGPVGLAALLTVQFFSPANIIMVDSSQNRLEAAKAFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            17403..18134
                     /gene="aphA"
                     /locus_tag="VH957_001133"
     CDS             17403..18134
                     /gene="aphA"
                     /locus_tag="VH957_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEQ8559048.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINATKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            18312..19844
                     /locus_tag="VH957_001134"
     CDS             18312..19844
                     /locus_tag="VH957_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEQ8559049.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVVVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            20007..20621
                     /locus_tag="VH957_001135"
     CDS             20007..20621
                     /locus_tag="VH957_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEQ8559050.1"
                     /translation="MLEIVSEELRRYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQAYI"
     gene            20780..21928
                     /locus_tag="VH957_001136"
     CDS             20780..21928
                     /locus_tag="VH957_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8559051.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            21977..22657
                     /gene="radC"
                     /locus_tag="VH957_001137"
     CDS             21977..22657
                     /gene="radC"
                     /locus_tag="VH957_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEQ8559052.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTTFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(22659..23354)
                     /locus_tag="VH957_001138"
     CDS             complement(22659..23354)
                     /locus_tag="VH957_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEQ8559053.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(23364..24008)
                     /locus_tag="VH957_001139"
     CDS             complement(23364..24008)
                     /locus_tag="VH957_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEQ8559054.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT         7485 a         4018 c         5017 g         7767 t
ORIGIN      
        1 ttaatcaaat ctcctttata ctgatattag gagaatgtta gatgtacccg cgtattagga
       61 atttgagaga agataacgat ttcactcaaa agtttgttgc aaatttactt tccttctctc
      121 atgcaaatta tgcaaaaatt gagagaggag aggttgcctt aatggcagat gttctaaact
      181 ctataacgtc agtattgatt atttattagg gcaaacagat tatccgtatc gttttcataa
      241 taaataaaag tctcgccttg atttgttcat tgacaactga ataaaccgag gtgggacttt
      301 cttgtttgtc gagcaattta gtgagatacg ccgtgatagg agcgataatt attagctata
      361 aaatagagtg gttctctatc tgccatgacc acaaataggg acaatgatac ttctgaacgt
      421 tcaggctgcc agcgtaaaag gccagtgggt gagattccca tgagtgattt aaccagtcat
      481 acccacggag gttgcaattt ttttgaaagg agtggaggtg tgaaaatagt aacatataaa
      541 aagcttgatg aatattggtt ttctcgaaca tactgcaaga aatattatta gagaagcaaa
      601 aagaatagct ataaaaaagt ttgaagaagc tcgcgaaatt gaccaaaatg cggtacaatt
      661 aagtaaatcg ccctttgaca atagaagact tggtattgct cctaaagata ttgtagaaga
      721 gttagtaggt attctactct ctgaagaaag tttagaaagt gagaattaaa gatgactata
      781 aaaaatcaaa aaaagtacaa aggtgtttat tgtgataaga atggtaagat attttatcaa
      841 gctgatcttg gtgtagatcc agtaacaggt aaacgagttc aaaagaaagc cagaaagaat
      901 tagtatggaa agccatttgg tacaatgaaa gaagcgtatg atgaactggt tcggattagg
      961 tatgagttta gtaataatct tagtattgaa aatgacaata tatcgtttga aaactatatg
     1021 aatactattt acctaagagc atataagcaa aaggttcagg ctgtaactta tgaaatagcc
     1081 ttaccacatc ataagttatt tattcagtat tttggttcta aacttttaaa gggaataaca
     1141 gcttgagatt gtgaatcttt tagtttacat attattgaaa attatgcaaa gaatttatgg
     1201 tcgcgattca aagcttgcat ggggtatgct gaaaggttag actatatttc aaaagtgccg
     1261 tgtaaggctt tggataatcc taaagggaaa catcccgata ctccattttg gacttatatt
     1321 gagtttcaga attttataaa atcgtttgat ttgcaagatt atgaagagct acaaagattt
     1381 acaactattt ggctatatta tatgacaggt gttcgtgtaa gtgaaggttt atcattatga
     1441 tgggaagata tcgatttcga acaaaaattt ttgaaagttc atacaacctt ggaaaaggat
     1501 gaaaatggaa attggtatcg taaagaccaa acaaaaacgc cagcaggaga acgtcttatt
     1561 gagttagatg atgtgacaat agtagtattg gaaaattgga gaagaaatca agtagtcaat
     1621 actgacacag atttcattat ttcacggttt ggtgaaccat tttgtaaatc aacgatttgt
     1681 cgagttatta agcacaaagc tcaagaagta ggagtaccag tgataacggg aaacgtcttg
     1741 cgacatagtc atgcttccta tcttattaat gttttgaaaa aagacattct gtacgttgta
     1801 aagtgtatgg gacatgctga taagtctaca actttgaata catatagtca ctggtttaat
     1861 gcattagata aaacagtatc tgaagaaata acccaaaatg taataagttc aggattagat
     1921 tccattttat accaaaattc ctgccaaaca actaattgat ataacgaagc ttattatatc
     1981 gcccatataa caggatgtgt tattgttaca gggtacttgc tttatgagct tgtttaagct
     2041 actaaaggtg tgtgccacta tacttccttc caaatttctg agaatttttg ttataatagt
     2101 aactatgaaa gatataatga taaaaaggtg ggctatcctt ttttttgtgg tattaacttg
     2161 ttcagggctt agtaaaatag tcctcgcagc tgattttcaa gtgggagcag aacatgcgat
     2221 tgtcgtagag gcagactctg ggagagttct gtatgagaaa gacgctaaga cgccagatgc
     2281 tattgcctct ttgaccaaat tggtgacggc ttatctggtt ttagataagg ttaaatcagg
     2341 ccagctgcaa ttatcagatc gagttaatct ctcagattat gccttcgagt taacaaaaga
     2401 taggtcttta agtaatgtac cttttgacaa aaaaacttat tcagttcaag acctgttgac
     2461 agctactttg gtagcaagct caaatagcgc tgctattgcg ttagccgaaa aagtggcgga
     2521 ttcagagctt cattttgtaa atcaaatgag agaacagcta tctcattggg ggattacttc
     2581 tggtaaaatc ctcaacgcct caggtctgcc aaatgaggtg ttaaaggaca atcgttatcc
     2641 tggttctgcg ttggaagaag aaaatacctt gagtgctcaa gatgttgcag ttgtgacgat
     2701 gcatttgtta gaagattttc ctgagatttt agagatcacc aaacaaacag aagttaattt
     2761 tgctggcaat tctattaaaa gttttaatca actcttacca ggtatggcta agggtagagc
     2821 aggagtggat ggtttaaaga ctgggacaac agacttggca ggtcattgtc ttgtggtaac
     2881 ttctattgaa aatggtatgc gagtgattac cgttattcta aatgccgatg gatctgataa
     2941 aaaccaaaac acgcgatttg agcaagcaaa tcgtttgttg gactatgtgg atagaactta
     3001 ttgtcgtcgt aagattctta aaaaaggaag tcttgtctcg gagcgatcgc tccctattca
     3061 agatggccaa gtaaaagaac taccggtatc tgttgccgaa gatgtaacca tcattttgca
     3121 acagggtgaa caagttccca aacctaaaca atttatgata tcagagactt ctttactagc
     3181 accgattact aaaggtgaag tggttgctta tttgacgtct ccaagaataa cagatcagtc
     3241 agtgaggtat ttaaaggaac ctaagcgtat tcctcttaaa gctagccaat ctcttaaaaa
     3301 agcctctgac ttacagctgt ggtggcgaga ttttcttgaa aaaagacgtt aaagataaga
     3361 ataaaataat tttaaaacaa tcaaaaaaga cagttatgaa agaatttttt cataactgtc
     3421 tttttagttt acagtgagta tgatttggaa tgataaaaaa attgatgtta tggttccatt
     3481 gtttgtaaaa gattttcagg actcatgttt gggaggatac gaatccggtt aagagaaaga
     3541 agtccattag ccgcgctagc tattccttca ttagtggtaa cacctaattt atagttaagt
     3601 ctagctgcaa tttgtaaggt agtgtcatta tatctaccag atggataagc aatggcaata
     3661 gtgttttggt ttaattgctt atcaagatag tcctttgaat ctttcatttc agttgtttga
     3721 acatcaggac tagcctgctc taaatcagga tgattcactg tatgatcttg gaaagacata
     3781 ccgaattgtt tcatttcttt catctgctta agagtcagat tggcagcgct tcctatttcg
     3841 gttagtcctg taataacatt attggtggct ttagcatcat atttttttaa gattgggtaa
     3901 gcaacgttgt agaaatcaat catactgtca tcaaatgtta gccatacaac ttttttagca
     3961 ggcaattcat tatttgaaag agcgcggtag acctcttcag gactcaaaaa atagtagccc
     4021 tcgtctttca ttttttgaag ttgttgatca aagagatctg ggttgacaat caaattagca
     4081 ttggccgtct cttcagggga cattacatga atagcatgat acattaaaat tgggatcttg
     4141 acaggtgttt cttgcttggt ccaagttaat ttagaatggg cctttttttg agattttgag
     4201 gaatcgaaat gagtcttctt aagttttgtc gtttcttttt ttgccgtctt tttgtgatga
     4261 aaaagactta ttttaggtac aaattgagag acatctgaca agccgaattt gttagaccct
     4321 tgatataaat agaaaatgag ggtcaaacca agaatgcagg caaataatag tataaggtta
     4381 atgagagtga aggcttttct tttttggcgc cgtttatgtc tattgttcat tacttgctcc
     4441 tttttttgat ataagtacct ctattgtaac attttttaga gaaaagaagg cttgaagtca
     4501 gccttttttc ttgttttttg gaagaacgtg tattaaggag taaaaaaatt gttgtcacag
     4561 ataacacttt aggaggtagc aaagactatg tgggactggt attcttatca cgtaaaaaaa
     4621 gcaatgaaga taaaagtgta gtgtacttta gaacttattt gagtgtttgg tgaggataag
     4681 aaaaaaaaag ggtactactc taggttatct gctgtcactt ttttttatat atggtatact
     4741 aaagatagat gtgaggtatg aaatgactta tgaagagact ctagaatgga ttcatgatca
     4801 cttagttttc ggcatcaagc caggcttaaa acgtatgctt tgggttcttg gacagttagg
     4861 aaatccccaa aaaaatgtca agggagtgca tatcgttgga actaacggaa aaggttccac
     4921 ggtcaatcat ttacaacaca tctttacgac agctggttat gaagtgggga cctttacctc
     4981 tccttatatt atggatttca aagaacgtat tagcataaat ggtcgaatga tttcagaaaa
     5041 agatttggtt attgctgcta atcgtattcg tcctttgaca gagcgtctag ttcaagagac
     5101 tgattttgga gaggtaactg aatttgaagt gattactttg atcatgttcc tctattttgg
     5161 tgatatgcat cctgtagata ttgctattat tgaagcaggc cttggcggtc tttatgattc
     5221 gaccaatgtt tttcaagcaa tggttgtggt ctgtccctca attggtttag atcaccaagc
     5281 tattttggga gagacttacg ctgatattgc cgcccaaaaa gctggtgttt tagaaggggg
     5341 cgagaccctt gtttttgccg ttgaaaaccc gtcagctcga gaggtttttt taacaaaagc
     5401 tgagcaggtt ggtgcttcaa tctgggaatg gcaagagcag tttcaaatgg ctgagaacgc
     5461 atctggctat cgttttacta gtcctttagg agttatttca gatattcaca tcgctatgcc
     5521 aggacaccac caagtgtcta atgcagcttt agctattatg acttgcttaa ccttgcaaga
     5581 ccgctatcct aggctaactc cagatcatat aagggaaggt ctggcaaata gtttgtggct
     5641 aggccgtacc gaattattag caccaaatct aatgattgat ggagctcata acaatgaaag
     5701 cgttgctgct ttggtagccg tcttaaaaaa taactacaat gataaaaagc ttcatatttt
     5761 gtttggtgcg atcgacacca agcctattgt agatatgttg gttgctcttg agcaaatagg
     5821 tgacttgcag gttactagct ttcattaccc taacgcctat ccattggaaa aatacccaga
     5881 acgttttggt agggttgctg atttcaaaga tttcttggcc ttgcgtaagc atgctaaagc
     5941 agatgacttt ttcgtgatta cagggtcact atattttatt tcagaaatta gacggtattg
     6001 gaaaaaacat attgaaaaaa gcgttctttt aacccattaa aaaagagaaa atgaaaagga
     6061 aaaggaaaaa actaatgaaa agggaaagac taatgtctat taataaggaa aaagcagaag
     6121 cagccattta tcagttttta gaggctattg gtgaaaatcc aaatcgagaa ggtcttcttg
     6181 acacgcctaa acgggttgct aaaatgtatg cggagatgtt tttgggactg ggaaaagatc
     6241 ctaaagagga atttacggct gtctttaaag aacaccatga ggatgtggtg attgtcaaag
     6301 acattagttt ttattctata tgtgaacacc acttagttcc tttttatggc aaggctcata
     6361 tcgcttattt accaagtgat ggtcgagtaa caggtttgag taaattagcg cgagcagttg
     6421 aagtagctag taaacaacct caactccaag agcgtttgac ctctcaaata gcggatgctt
     6481 tagttgaagc cctcaatcct aaagggactt tagttatggt agaagcagag cacatgtgca
     6541 tgaccatgcg aggcatcaaa aagccaggta gtaaaaccat taccaccact gccagaggct
     6601 tatacaagga aagtcgtgct gagagacaag aagttatttc tctaatgaca aaagattagg
     6661 agaacttatg aaaattggaa agtttgtgat tgagggcaat gcggctatca tggggatttt
     6721 aaatgtgact ccagattctt tttcagatgg ggggtcttac actactgtgc aaaaagcatt
     6781 agatcatgtt gagcaaatga ttgctgatgg ggctaaaatc atcgacgttg gtggagaatc
     6841 agcacgtcca ggttgccaat ttgtaagcgc taccgatgaa attgaccggg tggttcctgt
     6901 gatcaaggcc atcaaagaaa actatgatat tctaatcagc attgatacct ataaaaccga
     6961 aacagctaga gcagctttag aggcgggtgc cgatattctc aatgatgttt gggcaggttt
     7021 gtacgacggt caaatgtttg ccttagcagc cgagtacgat gcgcctatca tcttgatgca
     7081 taaccaagac gaagaagttt atcaagaggt aacacaagac gtttgtgatt ttctaggcaa
     7141 tagagcacaa gcagctcttg atgctggcgt gccaaaaaac aatatttgga ttgatccagg
     7201 atttggattt gccaaatctg ttcaacagaa tacggagtta ttaaaaggat tggaccgcgt
     7261 ctgtcagttg ggctatcctg tcttgtttgg tatttcgaga aagcgtgtcg tagatgcctt
     7321 gttaggcggc aacaccaaag ctaaagagcg agacggagcg acagcagcct tgtctgctta
     7381 tgcccttgga aaaggctgtc agattgtacg cgtacacgat gtcaaggcta atcaagacat
     7441 tgtggctgtg ttgagccagt tgatgtgagg acttatggat aaaatcgtat tagaaggttg
     7501 ccgtttttat ggctaccatg gagcctttaa agaagaacag acccttgggc aaatttttct
     7561 ggttgattta gaattgtcag tcgatttgca agcagcttct ttgtcagacc aattaacaga
     7621 tacggtccat tacgggatgg tgtttgatag tgtccgtcag ttagtggaag ggggaaagtt
     7681 tattttgatt gaacgtttag caggtgcgat ttgtgaacag ctttttaacg aatttccacc
     7741 tattgaagcc atcaaagtgg ccattaaaaa ggaaaaccca ccgattgcag gccactataa
     7801 ggcagttggt attgaattgg agagacagag atgaccattg tttatttaag tttaggcacc
     7861 aatatggggg accgagcagc ttacttgcaa aaagctcttg aggctttagc tgacttacct
     7921 caaacacggt tgcttgctca atcatccatt tatgaaacga ctgcttgggg caagacaggc
     7981 caggctgatt ttctcaatat ggcctgtcaa ttagatacac aattaaccgc ggctgatttc
     8041 ttaaaagaaa cacaagctat tgagcaatct cttggtcgtg tgaggcatga aaaatgggga
     8101 tcaagaacta ttgacattga tatcttgcta tttggagaag aggtttatga cacaaaggaa
     8161 ttgaaagtgc cacaccctta tatgactgag cgtgcttttg ttttaatccc cttattggaa
     8221 ttgcagccag atttaaaatt gcctcctaat cataagcttt taagggatta tcttgcagct
     8281 ttagatcaat cagatatcac gctcttttca gctcaacaga cagagttcta gactctgttt
     8341 tcggagtaat gcctgctata agccaatcca taaagttttg ccaaattcat cgttattttt
     8401 tctaaaattt gatataatag tatcggcttt atgccgattt ttttacgcgt ataagaagtg
     8461 ataaaagaaa gaagataact atgataactg aacttcatgg gattgatatt cgagagaatg
     8521 aacccctaaa acattacact tacactaagg taggtggccc agcagatttc ttggcttttc
     8581 ctagaaatca ctacgagcta tcacgcatcg ttgtttatgc caacaaagaa aatatgcctt
     8641 ggcttgtttt gggaaatgcc agcaatctca ttgtgcgaga tggtggtatt cgtggctttg
     8701 tcatcatgtt tgataagcta aatgcagtgc acttaaatgg ttatacctta gaagccgaag
     8761 ctggtgccaa tctgattgaa acaacgaaga ttgccaaatt ccatagttta acagggtttg
     8821 aatttgcatg tggcattcct ggaagcgttg ggggtgctgt ttttatgaat gcgggtgcct
     8881 atggtgggga aatatcacat attttcttat ccgctaaggt gcttacctca agtggagaga
     8941 tcaaaaccat ttcagctagg gatatggctt ttggttaccg tcactctgcc attcaagaaa
     9001 caggtgacat tgtcatttct gctaagtttg ctcttaaacc gggtaattat gatacgatca
     9061 gccaagaaat gaatcggtta aatcaccttc gccaactaaa acaaccttta gaatttccat
     9121 cttgtggatc tgtgtttaag cgcccgccag gacactttgc aggccaatta atcatggaag
     9181 caaatcttaa agggcatcgg attggtggtg tggaagtttc cgaaaaacac gctggtttta
     9241 tgattaatgt ggcagatggc acagctaaag attatgaaga tttgattgct tatgtcattg
     9301 agacagttga aaaccattct ggtgtcaggc ttgaaccaga agttcggatt attggggaaa
     9361 acctgtaacc attattgata attaaagaaa gtaccgtgga ggatttatga caattgacta
     9421 agccaattat cacatttaac aatgtttcaa aaacatttga ggacagtgga acacaggttc
     9481 taaagaacat taactttgac cttgaagaag gaaaatttta caccctgctt ggagcttctg
     9541 gctctggaaa atcaactatt ttaaatatta tggcgggcct actagatgcc agcagcggag
     9601 acatttattt agatggggaa cgtattaatg atttgccgat taataaacgt gacattcata
     9661 ccgttttcca aaattatgcc ctcttccctc atatgactgt ttttgagaat gttgcctttg
     9721 ctttgaagct gaagaaagtg gacaagaaag agattgctaa gcgcgtgaaa gaaaccttga
     9781 aaatggttca attagaaggg tatgaaaatc gttctatcca gaagttatct ggtggtcaac
     9841 gtcaacgtgt tgccattgcg cgtgcgatta tcaatcaacc gcgtgtggtc ttacttgacg
     9901 aaccactctc agcccttgat ttgaaattaa gaacagagat gcaatatgaa ttacgtgaat
     9961 tgcaacaacg tctaggcatt acctttgttt ttgttactca cgatcaagaa gaagccttgg
    10021 ccatgagtga ttggattttt gtcatgaatg aaggtgaaat tgttcagtcg ggaacaccag
    10081 tggatattta cgatgagcca attaatcatt ttgttgctaa ttttattgga gaatctaata
    10141 ttattaacgg taccatgatt gaagactatc ttgtctcctt taacgggaaa gaatttgaat
    10201 ctgtggacgg tggaatgcgc cctaatgagc ctgttgaagt ggttattcgt cctgaagatc
    10261 ttcaaattac tttgccagaa gaagggaaat tacaagttaa ggttgatacc caattattcc
    10321 gcggggttca ctacgaaatt attgcctatg atgaattggg taatgaatgg atgattcatt
    10381 ctacccgcaa agctatcgag ggagaagtta tcggattaga ctttacccct gaagatcttc
    10441 atatcatgcg tcttaatgag actgaagagg aatttgatgc ccgtattgaa gaatatgtgg
    10501 aaatggatga gcctgaagat ggattgatta atgccattga ggaggagcgt aatgaagaaa
    10561 acctctagtc ttttttcgat tccttacttc ttatggattc tcttttttgt tgtggcacca
    10621 gtcactctct tgttttacaa gtcctttttt gacatagaag ggcgcgtgac cttagccaat
    10681 tatgaaacct tttttagctc ttggacctat ttgagaatga gtgtgaattc tattttatac
    10741 gctggtatta tcacactcgt cacgctctta atttcatatc ctacggctct ctttttaacg
    10801 cgcctaaagc acaagcagtt gtggcttatg ctcattattt tgccaacttg ggtaaactta
    10861 ttgctaaaag cctatgcctt tatgggaatc tttggtcaac aaggagggat taacagcttt
    10921 ttaactttta tggggattgg cccgcagcaa atccttttca cggatttctc cttcattttt
    10981 gtagcctctt acattgagct tccttttatg atgttaccga tttttaatgc tttggatgat
    11041 attgaccata atgtcatcaa tgccagtcgc gatctaggag ctagtgaatt tcaggccttc
    11101 tcaaaagtta tttttcccct ttctttaaat ggggttaggg caggtgttca gtctgtcttt
    11161 atcccaagtt tgagtctctt tatgttaacc cgtttgattg gtggaaaccg cgtgattaca
    11221 cttggtacag ccattgaaca acattttttg accacccaaa actggggaat gggatcaacc
    11281 attggtgtcg tcttgatttt gaccatggtt gctattatgt ggctcacaaa ggagaaaagt
    11341 aaatgaaaaa atttgccaat ctttatttag cgagtgtctt tgttttactc tacattccta
    11401 ttttttattt gattttctat tctttcaaca aaggtgggga tatgaatggt tttacaggat
    11461 ttacccttga gcattaccaa accatgtttg aggatagtcg tctcatgaca atcttactgc
    11521 aaacctttgt ccttgctttt agtagcgctc tactagcaac gattattggg acctttggag
    11581 ctatctttat ccaccatgtt agaggtaagt accaaaatgc catgctatca gccaataatg
    11641 tcttgatggt atcaccagat gtcatgattg gggcttcctt tttaattctt tttacatcat
    11701 tgaagtttca gctgggcatg tcttcagttt tattaagtca tattgctttt tcgattccta
    11761 ttgtggtttt gatggtgttg ccgcgcttga aagagatgaa tcaagacatg gtcaacgccg
    11821 cttatgattt gggagctaat tatttccaaa tgctcaaaga agtcatgctg ccatacttaa
    11881 caccagggat tattgcaggt tattttatgg cctttaccta ttccttagat gattttgcag
    11941 tgactttctt tttgactgga aatggtttta ctactttatc tgttgagatt tattcgcggg
    12001 ctcgtcaggg aatttccttg gatatcaatg ctttgtcaac catcgttttc tttttctcca
    12061 tcctcttagt gatcggttat tattatatgt cacaggacaa ggaggaaaaa catgcgtaaa
    12121 ctttattcct ttctagcagg agttttgggt gttattgtta ttttaacaag tctttctttc
    12181 atcttgcaga aaaaatcggg ttctggtagt caatcggata aattagttat ttataactgg
    12241 ggagattaca ttgatccagc tttgctcaaa aaattcacca aagaaacggg cattgaagtg
    12301 cagtatgaaa ctttcgattc caatgaagcc atgtacacta aaatcaagca gggcggaacc
    12361 acttacgaca ttgctgttcc tagtgattac accattgata aaatgatcaa agaaaaccta
    12421 ctcaataagc ttgataagtc aaaattagtt ggcatggata atatcgggaa agaattttta
    12481 gggaaaagct ttgacccaca aaacgactat tctttgcctt atttctgggg aaccgttggg
    12541 attgtttata atgatcaatt agttgataag gtgcctatgc actgggaaga tctgtggcgc
    12601 ccagaatata aaaatagtat tatgctgatt gatggagcgc gtgaaatgct aggggttggt
    12661 ttaacaactt ttggttatag tgtgaattct aaaaatctag agcagttgca ggcagccgag
    12721 agaaaactgc aacagttgac gccgaatgtt aaagccattg tagcagatga gatgaaaggc
    12781 tacatgattc aaggtgacgc tgctattgga attacctttt ctggtgaagc cagtgagatg
    12841 ttagatagta acgaacacct tcactacatc gtgccttcag aagggtctaa cctttggttt
    12901 gataatttgg tactaccaaa aaccatgaaa catgaaaaag aagcttatgc ttttttgaac
    12961 tttatcaatc gtcctgaaaa tgctgcgcaa aatgctgcat atattggtta tgcgacacca
    13021 aataaaaaag ccaaggcctt acttccagat gagataaaaa atgatcctgc tttttatcca
    13081 acagatggca ttatcaaaaa attggaagtt tatgataatt tagggtcaag atggttgggg
    13141 atttataatg atttatacct ccaatttaaa atgtatcgca aataagcact caaaaaggct
    13201 ggtatttctc cagccttttt aatgtatcga cagatgacgt caccagtaca cgcgataggg
    13261 acggccaacc ttggtaaaaa tttgttggct gttcagttgc ttattttctt ctaaataagc
    13321 aatgtattta cggacagaga catgggataa gtgacaagcg gaagctaatt cttggatagt
    13381 aaaaggttga tcaaaggctt tgatattttc cataatccac tggaaagtgg attcagataa
    13441 gcctttttct aacaattgtt tgtttttagt gtcttttttg ctagtcaaac atttcagttg
    13501 gtcaatttgg gcctgctcta gttgctgatt ggccaaatgt tctcgatgtg taacaaactg
    13561 ttggatgctt tcttgaaagc gttcaaaggt aaagggcttg atgaggtagt cgataattcc
    13621 taaatgaaaa ccatctcgga taatattccc atcatttgcg gctgaaataa taatgacttc
    13681 gcaaggaata tgctgagtac gccatttctc caaaaattga atcccattgc catctgtaat
    13741 atgaatatcc agtaaaatga ggtcaattgc gtaatcagta agtatgcttt gaacagcttt
    13801 catagagtcg ctggatataa tgcgatcaaa aagatttagt ttttcgaggt aattgcgatg
    13861 gataaaatcc accataggat catcttcaat gattaaaacg ttcatgttgc cctcctacat
    13921 aaggtgttgt cactgagaac tgtaactcgg ttacggtttg atgttgatgg aattgggaat
    13981 ttgtatcggt caagagctgt tgaaaataag gtaagtcaaa aataggctgt acccgctcca
    14041 aatcaatcca attgtctgtc aaggtgtaat ggctgattaa atgattctga tcatgttgaa
    14101 tactcaaaac gagtgatttg ggtctcagtg tggttagaag attagtatgg ataaagcggt
    14161 aaatcatcaa accattatta agttgattct tggtggcaga atgaggaatc tcgcttaaaa
    14221 catcaatctt gagatggaca tttaattctt ggtatttctc ttgctctcca atgagaaaac
    14281 tagctagaag aggctcctta acaaggacag ataagctagt gagaatttca ttttcgggct
    14341 ccaaaatact gtctaaataa attttcaatt ggtcataata agcaatatcc actaagccat
    14401 aaataacatg caattgattc atgaatttat gagtttgggc ttgtagagca gaagcatagg
    14461 cagtggtata ggctagctga tccaaggtat caatagcctt aactgcttct cgcatgaaaa
    14521 taatgtggcc tcggtgatcg tttttgacac agatgggtga aatggctaac aagtagtctt
    14581 cctcaccata ccgaaagagt tgttcatgcc cctcttgcaa actaagtttt ggaaaatcag
    14641 gaaagaggtg attgaaactg ttgccagtag gttttcccaa ctggcatttc cgagcaatta
    14701 atttttgtcc agcctgattg cagagctgta agataccagc tttatctacc acaaatacgg
    14761 cggcttcgat ttgatccaac atggcattac gctcttcaaa gagctggtaa atttcacttg
    14821 gttctaactg gtgcagttga cgcttgagtc gaaaagaaat aaaactggtg accagtaaac
    14881 taataagaag acaaaggagt aaagacaggg tataattgcg ttttgacgtt aaagccacat
    14941 catttagggt agttagttta atgccaaccg caatagcacc aatctgtttg tcaccgtcaa
    15001 acacaggtac tagatagcga agtgactttc ctaaagtgcc cttggcggta gagataacct
    15061 tttttcctgc tagaacagcc tcctcatcac ctccttgaaa aggttttccg atatttttcg
    15121 ggttaggatg ggtgagtcga atccctttca tgttcatcac gaccacataa tcaaggttat
    15181 agatggaggc aatggagttg gtataggctg ttgttttagc atttggttgg ttgtttagga
    15241 gtaattcttt aattgcttga tgacttgcta acatttttcc agttgacgtt agcaaatggg
    15301 tttcctgatt tttgatggaa aggaatgtca tattcctgtt ttccatgacg atcagcatgg
    15361 aacagctatt gtggtgttag cagccatctt taatagtttg aaacttcttc aaaaatccct
    15421 tgatgaggta tccatcgtgg tgaacggtgg tggatctgcg ggattatcca ttacccgtaa
    15481 attattagca gcaggtgcta cgaaagtgac agtagtggat aaatttggca ttatcaatga
    15541 acaagaggca gatcagttag caccacacca tttggatata gcgaaagtca ctaatcgtga
    15601 gtttaaatca ggtaccttag aagatgctct tgaaggagca gatatcttca ttggcgtatc
    15661 agtaccagga gtcttaaaag cagagtggat tagtaaaatg gcagcgcgcc cagtaatttt
    15721 tgccatggcc aaccctattc cagagattta ccctgatgaa gcccttgaag cgggggctta
    15781 cattgtaggt actggccgta gtgattttcc taaccagatt aataatgtcc ttgcctttcc
    15841 aggtattttt aggggagcat tagatgcacg ggcaaaaacc attactgttg agatgcaaat
    15901 tgctgccgca aaaggtattg ccagtcttgt tccaggtgac gctttgagca ctactaatat
    15961 tattccagat gcctttaaag aaggagttgc tgagattgtc gctaaaagcg tcaggtcggt
    16021 agtccttaaa tcatagaata tatgaaaaaa agagaaagtt atactttaaa tcacaaaata
    16081 agtagaagca tatttctagc ttctacttat tttgtgatta gctaatatca ttatcaataa
    16141 taactttcaa ggcgttattt gcaccagcat gtttaaaggt ttcataagct ttttcaactt
    16201 ctgaaagttt aaaatgatgt gtaataagtc ttgttgcgtc aatctttcca gttttcaaga
    16261 catttagtag catttcagtt gtattggcat taacaagtcc agtgtttaag gtgatatttt
    16321 taatccataa ttcatccagg ttgaaatcaa ctggtttccc atgaacccca acgttagcaa
    16381 tatgcccacc tactgatata attttttggc aaatatcaaa tgtcgcggga taaccaacac
    16441 actccatgga aatatcgaca ccacgtccat tggttatatc gtcaatgata gccttgactt
    16501 cttcactact tcctgaacaa atcgtgtgtg tggctccaaa cgctttagct gcttcaaggc
    16561 gattttgaga tgagtcgacc ataataatat tggctggaga gaaaaattga acggttagta
    16621 gggctgcgag tcctactgga ccggcaccaa caatacaaac attatctcca ggattgacat
    16681 gtgatggcaa gacaccaatt tcatatgaag ttggtaaaat atcagaaagc atgacaagtg
    16741 cctcatcatc aatcgtatca ggagcatgat agagactacc atctgcatgt gggatatgga
    16801 catattccgc ttgtgttcca ttaattaaat ggccaagaat ccaaccgcca tcttcacaat
    16861 gtgacgaaag gcctcgttta caataataac aggtatgaca tgatgtgacg caagaaataa
    16921 tcactttatc tccgatttta aagttagtaa ccgcatcacc gacctcctta acaattccaa
    16981 ttccttcatg accaaggatt gttccttctt tacatgcggg aacatcccca cctaagatat
    17041 gcaaatcagt tccacaaata gtggttttta ccaactggac gatagcatct gtaggcttta
    17101 taatgactgg ttttggtttg tctatgagct gtagatttcc ggttgaaagg taagttgctg
    17161 ctttcatatt taactcctta taaggttgag aggtaatcaa ccaattcatt tttacacaga
    17221 tattataata gtttaagaaa gggttttcaa tattttttaa atcgattatg ataatttttt
    17281 agatcatctt tgttgaataa cttcatcctt attcagaact taaagggcac tattataaga
    17341 atttgaaacc gctttactta aaccgtgtat ttttgtacaa taatgattaa ggaggttttt
    17401 agatgaaaaa agaatttacc agtatcctgt ttacagttag tttttgtgga atcatagcat
    17461 tgcctgtcga agctagtggc cctaaagttc cttatacaca agaaggtata acggccattt
    17521 caaatcaggc aacagtaaaa ttgatttcta ttgctgatat cgcgagcagt ttagaaggac
    17581 aaaaacctat aacggttagt tttgatatcg atgatacttt gttatttact agccaatatt
    17641 ttcagtacgg caaagaatat ataactccag gctcatttga ttttttgcat aagcaaaaat
    17701 tttgggactt agtcgctaaa cggggagatc aggattctat tccaaaagag tatgcaaagc
    17761 aactaatcgc aatgcatcaa aaacgaggag ataaaattgt ctttattact ggccgaactc
    17821 gaggatcgat gtataaaaaa ggtgagattg ataaaacagc taagtcactg gctaaagatt
    17881 ttaagttaga caagccaata gctatcaatt atacaggaga taaagctgtg aagccgtatc
    17941 agtatgataa aacatattat ataaagaaaa acggctcaca aattcattac ggagatagtg
    18001 atgaagatat aaatgctacc aaagaggcag gtgcaagacc tattcgcatt ttaagagctc
    18061 ctaattcaac caatcttcct ttgccaaaag ctggaggata cggagaagag gttttagaaa
    18121 attcggctta ttagtcaaat atttgtgtaa gaaaggaagt aacagtaatt tctttcatca
    18181 ccccactgag taaccaatag cccagtgggt tttttgggtt acagaaatca gttctaaaaa
    18241 agaatcactg gtaacttaag gttgtctttg atacaatggt aacagtgtat ttaaaagaaa
    18301 gagaggacaa catggaaaac cataaaaatg aattcacctt ttccaacaaa tcaattattg
    18361 cctatgtttg gcgtggtgtt gtggttggta ttattgctgg tgttattgtt agtttattcc
    18421 ggttgttaat tgaagtgaca gctgactggg tgattgaatg gtaccgatac gctcatatca
    18481 attcgctgtt gctacttcct atactaagtg tcagtttgtt agctgttctt tttgtaggtt
    18541 ttttagtaaa gtctgattct gatataaaag gatcagggat cccccatgtc gaaggagaac
    18601 taaaggggct aatgtcccca gattggtgga gtgtcctttg gaaaaaattt ttaggaggaa
    18661 tcatggctat ttctatggga tttatgctcg gtcgtgaggg tccttcgatt cagttaggtg
    18721 ctatgtcagc caaaggatta gctaagtttt taaaatcgag tcgtttggaa aagcgagtgc
    18781 taattgccag cggagcagca gcagggctat cagcagcttt taatgctcca atagcaggcc
    18841 tcttgtttgt tgttgaagaa atttaccatc atttttcgcg tttaatttgg attacagcgc
    18901 tagtggctag cttagtggct aattttattt ctctgaatat ttttggattg aaaccagtct
    18961 tagcaatgtc agaggcgatg ccttttttag gactcaatca atattggttg ttgcttttac
    19021 ttggattatt tctaggctgc ttaggctatt tatatgagat agttatcctt aattttaata
    19081 aactttatgt tattttaggg agttggttac atctgccagc ttatttttac ggtattatta
    19141 tggtttttct aattttaccg attggctatt atttaccaca gttacttgga ggaggacatg
    19201 gtttaatact ttctttatcc aatcaacaat tgcctttgat gactatcttc ttttatttta
    19261 ttattcgatt tattgttagt atgtttagtt atggaagtgg cttacctgga ggtatttttt
    19321 tacccatttt aactttaggt gctttggcag gcctattatt tgggcaaata gcttctcaat
    19381 taggtttatt gaaccaatct tttctttctc tttttttgat attagggatg gcagggtatt
    19441 ttgcggcaat ttcaaaagca ccactgacag gcatgatttt ggtaactgaa atggtaggtg
    19501 atttgaaacc cttaatggcc atagctgtag ttacttttgt ctcctattta gtgatggatt
    19561 tgttaaatgg acagccaatt tacgaagcta tgctagataa gatggcaatg aagcatccaa
    19621 ctaatcttgt tgaaccaaca ttaattgaat tgactgttgg tgataagatt gcagggaaat
    19681 atgttaaaga gttaaagctt ccagaaaatg tcttaattac aacccaaatt caccatcaaa
    19741 aatctcaagt tgtgtcaggt aacacgcgcc ttttatcagg agcaactatc tttttggtcg
    19801 ttaatgaagc tgatacaggt tttgtccgtg aggtattgat gtaggtatta atttatcaca
    19861 attcggaaag ttcgagcttg tcttttagac taagtctttg aacgttttac tgctagagtt
    19921 tcatctgaac caaagtgaaa cgcttttgat gaagtcaagt aggctttttg ttatactaac
    19981 aataaagata agctaaggag gctgagatgt tagaaattgt ttcagaagag ctacgtcgct
    20041 atcaagaaca aaaattgatt gagtaccgta acaaaaatca gttagcccca aaaggaggca
    20101 ttgtatttgc aggtgattct ctcattgaat tttttccttt aaaaaaagct tttggttcat
    20161 gtttgcctat tattaatcga ggtattgctg ggatagatag tcagtggtta ttgcgccatt
    20221 tttctgtcca aattactgat ttagagccta aacatatttt tttattaatt ggttgtaatg
    20281 atatcgggct tggatatgat aaatgtcata ttgtcaagac tattgtagag cttattagcc
    20341 agattcgtag tcattgtgtc tacagtcaga tttatctctt atctttatta ccagtttcca
    20401 acaatccccg atatcagaag actgtcaaaa taagaacaaa tgctatgatt gatgctatta
    20461 ataaagattt agcaatgatt ccaactatag aatttattaa tcttaatact tgtcttaaag
    20521 acgaaaaagg tggtttatca gatgagaata ctctagatgg tttacatctt aattttccag
    20581 cttatgctaa actagctgaa attattcaag cttatatcta gcaaataaat gtactaatag
    20641 cgatgaggca agaagtcaga tagcagatgg ttcatcaatc aattaagaaa aaagttatca
    20701 agataccatt aaaaatagtt gctcaaagtt ctttcaaatc aaaagattat gatatcgcta
    20761 tgttgagttt tagtgtataa tgataattaa aggagttacc atgaaatttg aaaaaaaaca
    20821 agtcttctat ttagtcctta cgtttatctt atgctatggg atcctagcaa actggcgaaa
    20881 tggaacggct atcgtcacga ctatttacaa aacaagcctt cctttttttt atggagcagc
    20941 aggtgcctat attgttaata ttgtaatgag cgcttacgaa aaggtatatg tttatatctt
    21001 taaagactgg tcacatgtct taaaagtaaa acggggtatt tgtttactgt tagcgtattt
    21061 gacatttttt attttaatta cttggattat ttccattgtc attccagact taattacaag
    21121 tattagtact ctaacaaaat ttgatactat aacgatacaa gaagttgtta acaatcttga
    21181 gcacaataaa ctattagcac gtactattca gtatattggt ggcgatggca aacttacaga
    21241 gacgattgct aactatagtc aacagttatt aaagcaattt cttactgttt tgacaaatat
    21301 tttaacatct gtcacagtta ttgcttctgc aattattaat ctttttatta gttttgtttt
    21361 ttcgttatac gttttagcaa gtaaagaaga tctttgtcgc cagggaaata ctttagtaga
    21421 tacttatact ggtaagtatg ctaaacgcat tcattacttg ttagagttgt tgcatcagcg
    21481 ttttcacgga ttttttgtta gtcagacctt agaagctatg attttaggtt cgctgactgc
    21541 tagtggcatg tttatattaa gattaccatt tgcagggact attggcgttt tagtagcttt
    21601 tacagcattg attccagtta taggtgcttc aattggagca gctattggat ttattttaat
    21661 tatgactcag tccatgtcac aggccattat ttttatcatt tttttaatta ttttgcagca
    21721 gattgaaggc aattttattt atccgaaagt agttggtgga tcgattggat taccggctat
    21781 gtgggtatta atggcaatta caataggcgc ttctttaaag ggaatagttg gtatgattat
    21841 tgcagttcct ttagcagcga cactttatca agtgattaaa gataatattc aaaaaagaca
    21901 agctattcaa aaaaaacaag tttcctaaaa ggaacttgtt tttttgtcga ataaaaagat
    21961 ggaggtaata tgataaatgt attctataaa atgtgatgat aataaagcca tgccaagaga
    22021 acgtttgatg cgactaggag cagagtctct aagtaatcaa gaattattag caattttatt
    22081 acgaacaggt aataaagaaa agcatgtctt agagctgtca tcctatcttt tatcgcattt
    22141 agacagtctg gcagatttta aaaagatgtc tttgcaagaa ttacaacatt tggcaggtat
    22201 aggaaaagtt aaagcgattg aaattaaagc tatgattgag ttggtttccc gaattttagc
    22261 gacagataag acattaactg atagcgtatt aaccagtgtt caggtcgctg aaaaaatgat
    22321 ggcagcttta ggagataaaa aacaagagca tttagtcgta ttgtatttag ataatcaaaa
    22381 tcgtattatt gaagaaaaaa ctacttttat tgggactgtc cgacgttcac ttgcagaacc
    22441 aagagaaatt ttatactatg cctgtaaaaa tatggcgact agtctcattg ttattcataa
    22501 tcatccttca ggaaatattg aacctagttc taacgattat tgctttactg aaaaaataaa
    22561 acgatcatgt gaagatttag gcattatctg tctagatcac attatcgtta gctataaaga
    22621 ttattatagt tttcgagaaa aatcaaccct tttttaaatc agaagtcatt gacgaataag
    22681 cggaacaatt gtagatcttc atctcgaaca ccttggagaa gttcaggatg ccactgaaca
    22741 cctaaaaaag gaatggcatc gttggttgat atgactgctt cgatggtacc atcacgtgga
    22801 tctctagcga ttacttttaa atccttagca acagttttta aactttggcg atgaaaagaa
    22861 ttaattaatg tcttatgacc gtaaatagga tataagatag agtctggctc aataatcatt
    22921 tcgtgtgata agaaatcaga aggcgcttct tgccaatgtg agtcaatgtg ttggttaaga
    22981 tttcctccta aggcaacatt cattaactgt gtaccacgac aaatccctaa gattggtttt
    23041 tttaatgtta tagcctcctt gatgatagct agctcaaatg tgtctcgctc tggtgaaaaa
    23101 tcatcatcaa aagcagcctt ctcttcttga taatattttg ggtcaacgtt ttgcccacca
    23161 attaaaatga ttttatcaac catagataca taagttttag cggcggcttc atcaccaatg
    23221 ggtaaaagaa gcggcagccc cccagattga gtgactgcct gtacaaatcc agtaggtgca
    23281 tatgaccatg ggagattatc caaagccata tttagtcttt gatttgcagt tattccaata
    23341 atcggtttgg tcattatacc tccttaatct agatgatttt gattcataaa atagagtagt
    23401 gtctggagct cactggtcaa atcgacagat tgaacaataa ctcctttagg aacttgtagg
    23461 tgaacaggag caaaactcaa gattcctttg attcctgctt caataagttg atcagtaact
    23521 tcttgagcat gaatgctggg aaccgttaag atagccgttt caatgtcagt gttcgcaatc
    23581 cgttctttga cagatgagat accatggact ggaatattat cagctgtttt agtaccaaca
    23641 agagcgttat catcggtatc aaaacccatg gcaatttgca tcttattacg atcatggaag
    23701 cggtaatgta atagagcacg ccctatatta ccgcatccaa ctaagataac gtttgttgta
    23761 gagtgatcat taagcaagtc agcaaaaaaa ttcatcaatt tggtaacatc atagccaaac
    23821 ccacgacgcc ccaattctcc aaaataagaa aagtcacggc gtacagtagc agagtcaatt
    23881 cccattgcat ctgcaatttg tttagaactg gctttttcaa cttggtcagc atggaatcgt
    23941 ttaaaaatac ggtaataaag tgataagcgc tttgcagtcg cttttggaat agatttgtca
    24001 ataaccacta ttttactcct tgtagatttc tcgttaaata tgtctgtctt tattgtaaca
    24061 aaaagattgt gaaaaatgca acattttgat tgtttttgta tgagttaaaa aagctaaaat
    24121 tagttttagc actatataat agtattcatt aggaaagtaa gttatgacag tcaaaatgaa
    24181 caacatgaat taatagcaat agaagcgaaa tcatttattg acattgtgat atgactaaaa
    24241 aacaaaattt aaagttgatt agacgactgt tttgctaaaa atttcac
//
LOCUS       DAUGOH010000025        23133 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUGOH010000025 DAUGOH010000000
VERSION     DAUGOH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23133
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.025"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            318..557
                     /locus_tag="VH957_001140"
     CDS             318..557
                     /locus_tag="VH957_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8559055.1"
                     /translation="MRKQEQDHHKQDVNQKKPEEMTKLERLQEENEYLRTEVAYLKKP
                     RELRLKEASLQKRRQKTIIKNGQRRALIRFSFKNG"
     gene            complement(705..1628)
                     /locus_tag="VH957_001141"
     CDS             complement(705..1628)
                     /locus_tag="VH957_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559056.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1621..2691)
                     /locus_tag="VH957_001142"
     CDS             complement(1621..2691)
                     /locus_tag="VH957_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559057.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2700..3626)
                     /locus_tag="VH957_001143"
     CDS             complement(2700..3626)
                     /locus_tag="VH957_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559058.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3626..5128)
                     /locus_tag="VH957_001144"
     CDS             complement(3626..5128)
                     /locus_tag="VH957_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559059.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYKKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5193..7163)
                     /locus_tag="VH957_001145"
     CDS             complement(5193..7163)
                     /locus_tag="VH957_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8559060.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYENAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            7494..8726
                     /locus_tag="VH957_001146"
     CDS             7494..8726
                     /locus_tag="VH957_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8559061.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            8894..10075
                     /locus_tag="VH957_001147"
     CDS             8894..10075
                     /locus_tag="VH957_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8559062.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFTMGR
                     Q"
     gene            complement(10227..11645)
                     /gene="sufB"
                     /locus_tag="VH957_001148"
     CDS             complement(10227..11645)
                     /gene="sufB"
                     /locus_tag="VH957_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEQ8559063.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(11658..12122)
                     /locus_tag="VH957_001149"
     CDS             complement(11658..12122)
                     /locus_tag="VH957_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEQ8559064.1"
                     /translation="MALSKLNHLYMAVVADHSKHPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHSTSRTKM"
     gene            complement(12109..13335)
                     /locus_tag="VH957_001150"
     CDS             complement(12109..13335)
                     /locus_tag="VH957_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8559065.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(13366..14628)
                     /gene="sufD"
                     /locus_tag="VH957_001151"
     CDS             complement(13366..14628)
                     /gene="sufD"
                     /locus_tag="VH957_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEQ8559066.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPELELPTIERIKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKISANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(14723..15493)
                     /gene="sufC"
                     /locus_tag="VH957_001152"
     CDS             complement(14723..15493)
                     /gene="sufC"
                     /locus_tag="VH957_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEQ8559067.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYIIPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(15615..16784)
                     /locus_tag="VH957_001153"
     CDS             complement(15615..16784)
                     /locus_tag="VH957_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEQ8559068.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(16791..17552)
                     /gene="mecA"
                     /locus_tag="VH957_001154"
     CDS             complement(16791..17552)
                     /gene="mecA"
                     /locus_tag="VH957_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEQ8559069.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(17698..18537)
                     /locus_tag="VH957_001155"
     CDS             complement(17698..18537)
                     /locus_tag="VH957_001155"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEQ8559070.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIVFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(18603..20528)
                     /locus_tag="VH957_001156"
     CDS             complement(18603..20528)
                     /locus_tag="VH957_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEQ8559071.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRIGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGKEPV
                     DVSTSKKNKIVALETKISRRRTLLQLLFGKVIPLVEVGFLLSQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLILNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            20726..22294
                     /locus_tag="VH957_001157"
     CDS             20726..22294
                     /locus_tag="VH957_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8559072.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKIAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYAEATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGAIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAIAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            22287..23027
                     /locus_tag="VH957_001158"
     CDS             22287..23027
                     /locus_tag="VH957_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559073.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     IAEEGSPQQIFENPTQDRTKEFLQRFLK"
BASE COUNT         7181 a         4808 c         4163 g         6981 t
ORIGIN      
        1 ctttttttgt acttttttat ttgcccgagt tgtaaaatga agtgcaacaa aaaagaggaa
       61 aagccttgaa ctacacccca aacgttagac aaaaaaatct aacgttcggg gtatttttta
      121 tgaaattaag tgatgaaggt acgaaataga catcgttaaa aaaaatacct actatccacc
      181 agagataaag caggaaataa tggataacgt tttgatagaa ggcccgccac aataccaagt
      241 atcacttgtt tatggcttgt tacatgcagg aactctccca agttgaatag cacaatataa
      301 gaaaaacagt tatactgttg agaaaacaag agcaagacca tcacaaacag gacgtaaacc
      361 aaaagaaacc tgaagaaatg actaaattag agcggcttca agaagaaaat gaatatctca
      421 gaactgaggt tgcttactta aaaaaaccga gggaactccg tttgaaagaa gcatctctgc
      481 aaaaaagaag acaaaaaacc attataaaga atggacaaag acgagctctg attagatttt
      541 cttttaagaa cggctaaatt gactcgttct acctactatt atcatcgatt attgcaacaa
      601 taaacgtatc aaaataaaac gaaaaggact tagtcctcta caatacaaaa ctaaatcctt
      661 tactaaaaat agagtgttca acttttgggg tcagtgcatc tcttttacaa ttctttttga
      721 tatttttcaa tttctgcttg gtttgcccaa acaaagtgat ttggtttgat ttcaaccatt
      781 gatggcttat ctaatgtata atcatgctgg tctggatgat agacaacaag ttctttttga
      841 cgctctaaaa ttggatctgg gataggcacg gctgataaca aagattgggt gtagggatga
      901 attgggttat taaacagttc ttctgtttct gcaacttcta caataacccc tttatggata
      961 accgcaatac gatctgaaat aaagcgaacg actgaaagat catgggcaat gaagagataa
     1021 gtcaaacctt tttcggcttg catccgtttg agaaggttta aaacctgtgc gcgaacggaa
     1081 acgtccaaag ctgaaatcgg ttcatcagca ataacgaatt cagggttcat tactagggct
     1141 ctagcgatac cgatccgctg acgttgacct cctgaaaatt catgagggta gcgcgtcaaa
     1201 tgctctgata gcaaaccaac ttcggccatc atgttcttaa ttttttcttt acgttcttcc
     1261 tctgttttaa acagattaaa gttataaaga ccttctgaaa tgatgtagtc aacggttgcc
     1321 cgttcattca aactagcagc gggatcttgg aaaatcattt gaattttacg aatgagctca
     1381 ttggcttctg attttgattt tctgccatta attactttcc catcgtataa aatttgacct
     1441 gaactagtat cgttcaaacc aataatagca cgaccaattg ttgttttacc actcccagat
     1501 tctccaacta aagaaaaggt ttctcctttt ttaataaaga aattagcatt tttaactgca
     1561 acaaattttt tctttccttc tccgaaggaa atttctaggt cttttacttc gactaatttc
     1621 tcagacattt ccttcctcct gttgtgacat tttccttaag attttttgat gcaaatcttg
     1681 aatgacttct ggtttttgaa cttttggagc ctctgggtgt aaaagccatg ttttggccca
     1741 atgagtctca gatacgttaa tcgccggagg tgctttttca aagtctaaaa ccatagcata
     1801 ttctgagcga agtgcaaagg catctccgat aattggtgaa taaagtgatg gaggcgttcc
     1861 tggaatagcg taaagttcac cagattcatc tgccaactgc ggtaagctag acagcaaact
     1921 ccatgtatag gggtgtcttg gatcatagaa aatctcttcg actgttccaa attcaacaat
     1981 ttctcctgca tacatgacag ccactttatc tgcaatgctt gccacaacac ctaaatcgtg
     2041 cgtaataaag ataatggtga aatgatattc tcgttgaagc gacttcaata actcaacgat
     2101 ttgagcttga atagtcacat caagggctgt tgttggctca tcacagataa gaatatctgg
     2161 acgacaagct aaagcaatag cgataacaat acgttgacgc attcctcctg aatactcaaa
     2221 tgggtaatct tcaaagcgtt ttttggcatt tgggataccc actttattca tgtaatcaag
     2281 ggccatttct ttagctttgg catgacttac tttttggtgc ttaataatca cttctgtgat
     2341 ttggctaccg atagttttaa tgggactaag actggtcatt gggtcttgga aaatcgttgc
     2401 gatttttgag ccgcgaatct ttgcccactc tttatttgtt tttaaatctg tcaattcttg
     2461 cccacgatag acaattgaac cattagcaat gcgtccatta gactccaaca tccctgtaaa
     2521 ggtctttgtt aaaacagatt tacctgagcc tgattcccct acaaaagcaa ggacttctcc
     2581 ttcaacaagt tccagtgaga cgttacggat agctgttaaa acacgatcac gcacatcaaa
     2641 ttctaccacc acatctttgg cagttaagat tacattattt tcttttgtca ttttaactcc
     2701 tatctatgtg aacgtgggtc actggcatca gccaagtttt gtccgacaat gtatagtggt
     2761 aacgatacta aaatcaatgt tactaaggga atccaaaaga ggtaggcatt tgttgttaag
     2821 ttgcttgaat aattagcaat caaacgtcct aaacttggag tggtggttgg taaaccaatc
     2881 ccaaagaagg ataagaaggc ctcagaagat acataaactg gtagcatttg tgacaacata
     2941 gtcatgataa ctgaaaccaa ttgaggcagg aggttcttaa cagcaatctt gtacattggt
     3001 gttcccaaag tttgactagc aaggttgtat tctaaatcac ggtaacgcaa gatttgaaca
     3061 cggatggagt aggcgacacc aatccatcca gtgatacaga aagctagaat caaattccaa
     3121 aatcctgcac ctaatgaata ggtcaaaaca atgataataa gcatagaagg gatatttgag
     3181 ataatgttat aaatttcaat cataacttta tcaaatgctt tagaaactcc ccatatggct
     3241 cctaacacta ccccaatggt gatattaatt agtgtcgcta taactgagat taaaatagaa
     3301 ttacgtgccc cataccaaac accatcaaac agagattgcc catttttgtc ggttccaaac
     3361 cagtactctg cattcggcca aatataacgc tttgaaaagt cattgatatt actaacgtca
     3421 ttaaagtcgt agttggcaaa cattggataa ataaagctca tcatcaagac tgtcactaaa
     3481 atcacgagca taaagactgt agatttttta gaaaaaaact gacgaaacac tgatttccag
     3541 taagaataag caggggtatc aatcacttcg gaggcttcac tatcgcgctc aacaaatcga
     3601 aatttagatt tatcaatcga ttccattact tacctccttt ttttgttgac aatttaatac
     3661 gtggatcgac aagggtcatg acaatatctc ctagtaaaag tgaaacaatt gacaagacag
     3721 tgaagataaa ggttaatcca acaatcatag aattgttagc agatttaata gaatcaatta
     3781 acattttacc catacccggg aaggcaaaga cagtctctgt taaggttgca ccaccaatag
     3841 caaggataat acttgcagga acccctgaca caattgggac catggcattt ttgaagagat
     3901 gccctctgta aatttcagat tctgataatc cttttgaacg cgcaaaacgt acccaatcgc
     3961 tggcctgaag gtcaacaaga tagcgacgga accagataac cgtagttgga atatttaaaa
     4021 ttcctaaaat aagggctggt aaaatataag atttaggatc agatgccccc agcattggga
     4081 aactatctgg taaaccaacc atgccaccta ggaagcgaac aacatagata acagcaatac
     4141 ttggtaaagc aagcatgaag gtcatggtcg ctgttgagaa acggtcaaaa taggtatttt
     4201 taaaccgagc cataaataaa ccaagaggca aaccaacgat ataggaaaac ataacaccaa
     4261 aaaaaccaat tacaaaagaa ttgtgaatca ttgatgggtc gacataatta ttgatggttt
     4321 tagtgtagga atctccctta ccatagttta ccttggtgat atcatccaat gattttggat
     4381 ttttgtagct acggctatag atatccactg acgatttctt agtgacacct gatgggaagg
     4441 tcacatcttg aagagctgtt cgtccttgcc cttgtgaaat aacctgaaga acaggaatat
     4501 tgctgtatgt tggataagat gttcctaagt ttagggtaac aaagttttgg tgaagataag
     4561 gaaattttcc gttagtatag aggagatatt tatgttttgt ccccgaacca acaagtgacc
     4621 agccaactga tttatctttt tctagacgaa tatacctagc taattttgga ttatctttat
     4681 cctgaatctt ccaagggtga tcaataacaa ctagatttga gaaaaagttc caaacacgtt
     4741 cgtaaatagg aatattgcga attgcataaa actgtttgct agtggggaag cgttttagct
     4801 gccagccatt gccaagagaa tcaatatact tcttatagat agctttgtta gcactagttg
     4861 cttctgtcgt tacactacta tctactttag aagcattatc ttttaattct ttgcttgaaa
     4921 aataattgac ataacccata cgttgaaaag ttagattttc atacgctact tttttatctg
     4981 gtgttgttgt cattttatta taattagggt cttgtttaaa gataaggctg gtaggtacta
     5041 gagtatatac gatggtgtat gttaaagccg ttaccaaaac taccgacact aacgatcgca
     5101 tgatacggtt taaaatgtat tttttcatag ttatcctcaa tagttcaaaa gaactccctc
     5161 acataaacga gaaagttctt ttgaacatcg ttttattttt caacgtgatc agctaacttc
     5221 tcagcatatt ttgcatttga cttagccttt gctttcatcc atttttcttt tgcattttcg
     5281 tattgttttg ctgtgacagg tttgtcttga agtttcattc ctttatatgc tagaggacct
     5341 ttagaccctg cccaagagaa gcccccgcta aatggaacgg ctttagtaac tcgtggagtg
     5401 ccacccaatg ccacaactgg aatatctacg gcattatctg taaggtaggc ttgtgctttt
     5461 gcgtaagctt tatagcgcgc atcgttgtcg tctgtaattg ctgctgcttc atcaagaaga
     5521 gtttggtagg tatcaagacc tgcagctgcc acaacatcct tattttgacc tgctttgatt
     5581 ccaagttttt ggataacaga tccaccacct actggactca tgatgtcaag gtaggtccgt
     5641 ggatcttgat agtctggtcc ccaccatgat gaaatgatat cgtagtcttg ttgttctggg
     5701 gtctcagcat agaagccttg ggcttcgtga gttgatgttt ctgtttcaag aacattgaca
     5761 atgacatttt ctttaccaag agatgcttca acagattgtt tgaaagactg ggcttcctga
     5821 acagttgctg cgtttgcttg gtcaacaggg taatctaatt gaactgggaa ggttacacct
     5881 tcagctgtca aagcttcttt ggcttttgca aactcagctt ttgctttttc aggattatag
     5941 aaaccatctt gagcatcagc taagttaacg tctttccatt catcaccaag ttttgccatt
     6001 tccttttcaa cttctgaacc aaaatcactt tctccaatgg tcacaaatgt tggtggcaca
     6061 agcatgttac gtaaggcttt tgttttggca tcttgacctg cagtttgggc ttggaatgac
     6121 gctcggtcaa aagcaaactg aatagcttga cgaaaatcct tgttgttaag agctttctta
     6181 ccggcatctt gttgtgcagg gtctttctta gtgtttttga aagaagtacg gttcaaattc
     6241 catgttaaat gacggatatc tccagtcaac attccgtaag taatgttatc agcatagttt
     6301 ttcttagctg atttgtaggt agggtcattt gggtaaagtc gtgcaacgct gaactcaccc
     6361 ttgtcaaagt tcttgtagaa cgaacctggg tctgaaccat ctgagtaagt caatttaaca
     6421 gattctatcc caacattctt agcatcccag tagttttcat ttttatggaa ttccatagat
     6481 gattttgagg tgaaggcgct caagaagtaa gcaccattaa caaggattga tgatggatcg
     6541 gttgtaccaa aatctttacc ttttgacttc aaaaatttcg cattaactgg gaaaagcaca
     6601 ctataagttg tttttgaatt ccagtagctt tcaggcttgt tcaaagtata ctgaacagtt
     6661 ttatcgtcaa gggctttgac accaacttct ttaaaatcta cttcaccatt ttggtaagcc
     6721 tttaagtttt ttattgaatc ttcaacaacg taaagagcat ctgatttatc gtcaaccgcg
     6781 tgcttcaaac cagtcacaaa atcttctgct gttactgggg catattcttc accatcagcc
     6841 gtataccaag agacaccatc gcgaagagta taagtataag tcagaccgtc ttttgaaacc
     6901 ttccaatctt tagcaagtga tggtactaaa ttaccatact catcgttttc caaaagacca
     6961 tcaaccattt gtgttatcac atcagtcgtt ccaccgccat tagtcaaaat ataatccaat
     7021 gattttggat cgttaacaaa aacgtacttg taggtttttg tagcttctga gccacctgaa
     7081 gcatttttat taccacaagc tgccaaagcg gatactgaca agatcgcaac acttacagct
     7141 gccaaccatt tacttttctt cataaaagtc acccctaaac tttatttttc attttttggc
     7201 aattgctaaa tgaaattggt taattgaaga cattatatca taaaactttc ttaaagaaaa
     7261 taatgaaatg aaaaattatc tgaatatttc gtagaatttt ctttatttta tacatttatc
     7321 tatatgaaag cgttatactc ctcttttaat gaggtttcaa ttagtttaat aaagattgtc
     7381 attctctcat ggtagcgttt tattatatca ttactcttgt gaggtaagtc attaccttag
     7441 acaaaaatat ggtataatta aaaaaataat acttgagtaa ggataatcta taaatgatca
     7501 aacgattaat ttccctagtg gtcatcgcct tattttttgc agcaagcact gttagcggtg
     7561 aagagtattc ggtaactgct aagcatgcga ttgccgttga ccttgaaagt ggcaaagttt
     7621 tatacgaaaa agatgctaaa gaagttgtcc ctgtcgcctc agtcagtaag ctcttgacaa
     7681 cctatctggt ttacaaagaa gtttctaagg gcaagctaaa ttgggatagt cctgtaacta
     7741 tttctaacta cccttatgaa ctcactacaa actatactat tagtaacgtt cctcttgata
     7801 agagaaaata taccgttaaa gaacttttaa gtgcgttagt tgttaataac gccaatagcc
     7861 ccgctattgc tttagctgaa aaaataggcg gaaccgaacc caaatttgtt gacaaaatga
     7921 aaaaacaatt aagacaatgg ggcatttccg atgcaaaggt cgtcaattca actggcttaa
     7981 ctaaccattt tttaggagct aatacttatc ctaatacaga accagatgat gaaaattgtt
     8041 tttgcgccac tgatttagct attattgcca ggcatctctt attagaattt ccagaagtac
     8101 tgaaattatc tagcaaatcc tccactattt ttgatggaca aaccatttac agttataatt
     8161 acatgcttaa aggcatgcct tgttatcgag aaggcgtgga tggtcttttt gttggttatt
     8221 ctaaaaaagc cggtgcttct tttgtagcta ctagtgtcga aaatcaaatg agggttatta
     8281 cagtagtttt aaatgctgat caaagccacg aggatgattt agctatattt aaaacaacca
     8341 atcaattgtt gcagtacctt ttaattaatt ttcaaaaagt ccagttaatt gaaaataata
     8401 aaccagtaaa aacgttatct gtcttagaca gtcctgaaaa aactgtcaaa cttgtagccc
     8461 aaaatagttt attttttatc aaaccaatac atacaaagac caaaaatacc gtccatatta
     8521 ctaagaaatc atccacaatg atcgcacctc tatcaaaggg acaagtctta ggtagagcaa
     8581 cccttcaaga caaacatctt attggacaag gttatctgga tactcctcct tctatcaatc
     8641 ttatccttca aaaaaacatt tctaaaagtt tctttttaaa ggtctggtgg aaccgttttg
     8701 tgaggtatgt caatacctct ttatagaata acacaatgct ttttgtatga cattgactga
     8761 cagagtactt ctgcagtctt tttcattttt atttaagcaa actaggctaa tcctaacaat
     8821 ttttcaaaaa aacttcacat tgtattagca aagtgatata ctgaaaatgc attacattta
     8881 aaggagtcgg aaattgacca aaagaattat actaactatt tttaccttta tttgcttttc
     8941 gatgatgcct cttgtccacg ccgaagatgt catggatatt acaaggcaag caggctacac
     9001 agttagtgag gttaatcgac caaaatcttc tattgtcgtt gatgcaaata gttcagatat
     9061 tctttggcaa gataatattg atattcctag ggatcctgct agtatgtcta aaatgtttac
     9121 gctttacatt ttatttgaag agctcgctaa gggaaaaatt acgatggaca ctactattac
     9181 ggcaactcca accgatcaag ctatcgctaa catttatgag attagcaata ataatatcgt
     9241 cgctggagta gcttatccta ttcgcgatct tattactatg acagctgtgc cttcatcaaa
     9301 tgcagcaact gttatgattg ccaattattt atcaaacaat gatgcttctg cgtttatcga
     9361 tcgtattaat gccacagcca aacaattagg catgactaac actcattttt caaacgctag
     9421 tggtgcagca gcacaagctt ttcaaggtta ttataatcct actaaatatg atttatctgc
     9481 ttcaaatatt acgaccgctc gagatttgtc caagttactc tatgccttct taaaaaaata
     9541 ccctgaaatt atctccttta caaataaatc tgttgtgcac actatggtag gaacgccata
     9601 tgaagaagaa tttcacacct ataaccactc tctcccagac aatcaatttg gtatgaaagg
     9661 agttgatgga ttaaaaacag gttctagtcc cagtgctgct tttaacgcca tgataactgc
     9721 caaaagaggc aaaactcgac tcattactat tgtcatgggg gtcggagatt ggtcagatca
     9781 aaacggagag ttttatagac atcctttcgt caatgccttg actgagaaag ggtttaaaga
     9841 tagtaagacc ttatccaaaa aagcacgcca aaaactcgaa aaattagtgc cacaaaccaa
     9901 aaaagaaaca tcacctaaac agcagcactt caaagccact aaaaagcaat cgtacttgga
     9961 aagagtcgaa gattttatga atcacaacca cactttcttg cttatttgct tagctatctt
    10021 tataattact atccttttac taagcctcgt tgtctttaca atgggacgcc aataatgaat
    10081 tatcaaaaac ctctgtcaaa gcacagaggt ttttgatatg ttatcttacg tgtttaaggc
    10141 aactaaaaac taaccacttg gggttagtac tacaactcat aaaatcctat ctcaaagatc
    10201 tttcagatgg ataagagaaa atgcaattaa ccgacagaac cttccatctc ataggaaatc
    10261 aatcgattga gttcgaccgc gtattccatt ggcaattctt tggtaaaagg ctccacaaat
    10321 cccatgacaa tcatctctgt ggcttcgctt tctgataagc cacggctcat gagatagtag
    10381 agttgttctt cagaaatctt agacactttg gcttcatgtt ctaacgccac ctgtgaatta
    10441 tgaatttcgt taaatgggat cgtatctgat ttagaaatat cgtccatcaa aatagtatca
    10501 cattcaatat gggaaacgga ttttttagat tgcttgttaa aagtcacttg gccacgataa
    10561 tctactttac caccagactt ggcaattgat tttgacacaa ttgatgatga tgtatgtgga
    10621 gcattgtgaa tcattttagc ccctgtatct tggtgttgac ctgcgttagc aaaggcaata
    10681 gacagcatgg tgccacgcgc acctggccca tcaagataaa cagaagggta cttcatggtg
    10741 gttttagctc ctagattgcc atcaatccat tccactgttg catccgtaag ggcgcgtgca
    10801 cgttttgtta ctagattata cacattgtct gaccagtttt gaatggtggt ataacgcatg
    10861 tatgcaccgt caagcgcaaa gatttcaacg atagcagcat gtaagctgtt acttgaataa
    10921 gtgggagctg tacatccttc aacataatga acacttgctc cttcatcaac aataatcaat
    10981 gtccgctcaa attgaccagt attttcattg ttaatgcgga aataagtttg caaagggata
    11041 tctaccttga cccctttagg aacataaata aaggtaccac cagaccaaac tgctgaattg
    11101 agggctgcta atttgttgtc tgttggcgga accagtttgg caaagtattg tttgaacaaa
    11161 tcaggatatt ctttgagggc ggaatcggta tctgtaaaga taatccctag cttttcaaat
    11221 tcacccttca tgttatggta aaccacttct gactcatact gagctgatgc tccagcaaga
    11281 taagcacgtt ctgcttctgg aattccaata cgatcaaagg tttcttttat tttttctgga
    11341 acatcatccc aagaacgagc tggcttatca gatgcttttt gatagtaaat gatatcatca
    11401 aagttaatat ctgataagtc tgctccccag gtttgcatcg gcattttatt aaaggtttcc
    11461 aaggatttta aacgaaactc caacatccac tcaggttcat ttttggcagc tgatagttcg
    11521 cgaaccactg cctcactcaa tccttttcct gtagaataaa tgggctctac atcatcgtga
    11581 aatccaaatt ggtagtcccc taagtcaatt ggctttggct ctactttctc atttatatca
    11641 gacatttttc ccttccttta cattttggtc cgtgaggtgc tgtgctgagc attggcactt
    11701 cgtttaatgg cttccttgag agcattccaa gctagggtag agcatttgat acgctgtgga
    11761 aattttgcaa ctcctgccaa caattctgct tcacctagct ctttttgagc aggattttcc
    11821 tgtccttgta ccatctctga aaaaatatca gctaacgcga gtgcttcttc tttactttta
    11881 ccaataacag catctgtcat catgcttgat gaagctgtgg aaatggtaca gccgttgcct
    11941 gcaaaagcaa tatcttcaat tttatcttcg tcaaacttaa cggtcaaaga aatcacatca
    12001 ccacaagtcg gattattcag ttgaacagcc tctacgccat ctagttgccc atgatgatgt
    12061 ggatgtttcg aatggtccgc taccacagcc atgtatagat ggttcagttt agagagtgcc
    12121 attgaaaaac tcctttgctt ttagaattgc ttcgactaaa cggtcacaat ctgccttggt
    12181 gttatagata taaaaacttg ctctaacagt tgctggtaca cctaaataac taagaagagg
    12241 ttgggcgcag tggtgccctg ctcttactgc aacaccttca tagtccaagg ctgttgccaa
    12301 gtcatgagga tgcaaatcat ccagattaaa agaaatcaga ccagatcttg cactaggctg
    12361 gcttggtcca tatatggtaa gcccctcaat agcttctaat ttcggcaaaa cataggctat
    12421 tagttctgct tcatgcgcat gtatatcagc catgcctagt ctctgaaggt aagaaatggc
    12481 tgcgcttagc ccaatagcac cagctatgtg aggtgttcct gcttcaaact tccagggcaa
    12541 ttctttccaa gtggcctctt gttcgtaaac aaaatcaatc atttctccgc caaattcaag
    12601 aggctccact tgattcaaaa gctcttcttt gccgtaaaga acacccaaac ctgttggccc
    12661 caacatctta tgagctgaaa aagcaaagaa atcacaatcc aagtcttgaa catcaatagc
    12721 caaatgtgga accgactggg caccgtcaac aacaaggtag gctcctttag catgtgccag
    12781 cttggcaatt tctttaatgg gattgatgca accaagaaca ttggagacat gtactaggct
    12841 aacaaaacgt gtttttgtcg tcaatttgtt tgccaaatcg tccatgtcaa gttggccatc
    12901 ttttaaataa acatagacta accttgctcc tgttttttga caggcttgtt gccaaggaat
    12961 gatattggca tgatgctcca taatcgaaat caacacctca tcttctggcg tcaagacctg
    13021 ctctgcaaac cgagcaaccc aattcaaact ggttgttgtt cctctggtaa agagcacttc
    13081 cttgcttgat ttagcatgaa taaagtcagc aacctgctgg cgactggcct catatttgtg
    13141 cgttgcacgt tcagccaagg tatgaactcc tcggtgaaca ttagcattat cttcttgata
    13201 ataggattgc aaagcctcaa gaacaagcgc cggtttttgt gtggtggcgg cattatccaa
    13261 ataaacaagg ggttcatcat tgacttgttg atttaagatt tgaaagtctt gtttgatgtc
    13321 ttttgcgtct agcaatacta acctctttct ttttggcagt aggtcttaac gattaagcaa
    13381 tttctcatct aaaaccttaa taatctcttg gcggactgat ggaataggaa tttcagcgat
    13441 aactgctcct aggaatcctc taataaccaa tcgttctgct gtttcttgat ccagtcctcg
    13501 actcatcaag taatacatat cttcagggtc aacctgaccg atagaagctg catgacctgc
    13561 tgttacttca ttttcatcaa ttaagaggat tggattggca tcggctcttg cttggtcaga
    13621 aagcatcaaa acacggcttt cttgttgagc atcagctccc ttagcgcctt ttagaatatg
    13681 accaatcccg ttaaacgtta aggtgccacg ttccaaaatc acaccatgct gtaaaatatg
    13741 accgaccgta cgttgaccat agttggtcac gcgcgtgtca ataccttgta cctgacgacc
    13801 acttgaggct gcaacaactt tcaaatcagc ttgtgagccc tgaccaatca aatcactgtc
    13861 aaaatcagca atgacattgc cttcattcat cacagctaag gcccaatcaa tgttggcatc
    13921 cttctctaaa cgtcctcgac ggctaatata ggttgtcact gaaggaccta agcggtcgat
    13981 agccgagaat ttaatctggc tgcctgcttg agcaatcact tctacactga tattagcgct
    14041 gatcttttga gtggcattgc caatagattc aaaacgctct aaataggtga acttactttc
    14101 ttttcctgca atcactagaa catgcttgtt aaaaggaacg tcactgtcac tatcttgtaa
    14161 gaaaatagct tcaataggag ttgtgatttc caagtgatca ggaacgtaga gcacggctgc
    14221 gctattaaaa taagcagtgt ggtaggcagc tagtttgtct tcatcaaaag ctaatgcctg
    14281 accaaaatga gcttcaatta cttctgggat ttcctcaagc gccgtataaa aatcactgaa
    14341 aacaactccc ttgtcaatta acgccattgg taactgttct aagactgttt gcgtgcctac
    14401 ctgaacaagc tttgggttat ctccaatagc tataaaatct ggaacactag ctagactttc
    14461 attttctgtt aaggtaccat ctcctagatt ccaacggtga aatttaatcc tttcgatggt
    14521 tggtaactct aattctggta tggcttctaa tgccgctaaa cgccgctctt gcagccaagc
    14581 aggctcagcg tgggcttgcg aaaaagccac tagtttttct tttgtcatct gtcaatcctt
    14641 tgtctctggt ttttaaattg gctgggtata tagaacatca cctagctttt tgtagaaagc
    14701 taaagtaatt gtctccaaaa acttaacttt cttccttgta ctcgattccc agatcctgtg
    14761 caatacctgc gtagccttct ttttcaagac gagtagccaa ggcagcatca ccagataaga
    14821 caatacgacc atccatcata acatgaacta ggtctgggat aatgtaattc aacaaacgtt
    14881 gatagtgggt gataatcata gctccaaagt ctttcccacg catctcatta acccctttag
    14941 agactacttt tagggcatca atatcaagac cagaatcaat ctcatctaac aaagcaaatt
    15001 taggctctaa catgagcaat tgaagaattt cattgcgttt tttctcccca ccagaaaaac
    15061 cttcattgag gtaacgctct gccatctctt ctttcatacc taacaaagcc attttctcat
    15121 caagtttggt gataaaatct cgcacggaaa tcttatcctc atctgcctta ccggcattca
    15181 ttgctgcacg cataaattca gcgttggtaa tccctggaat ttctgaaggg tattgcatgg
    15241 cgagaaaaag tcccagtctc gcacgctcat caacttctag atcgagaata ttgaccccgt
    15301 caagcaaaat ctgcccttgg gtcacttcgt agttaggatt tcccataata gctgctgaaa
    15361 gggtagactt tcctgtccca tttggcccca taatggcagc tacttcccca gttttaagag
    15421 ttaggttaac ccctttcaaa atctctttac cttctattga aacatgtaaa ttattaatct
    15481 caagaattga catgatacac cccttatttt ctctgtcatc tataccatct caagaaaaga
    15541 cagtgtcatt tgcactgctt tttttataat ggtcactgca tctattatag caaaaaaagc
    15601 cttactcggc ttttttagtg tttcaaatcc ttcttttctt tccatttcag aagcattgct
    15661 tgacgataat cactattacc aataaacttt aacaagttaa acaaaggcgt tcgcttttca
    15721 ccccagatct ccaatccttc aataaaaact tctaaaccaa ataaaagtcc aagcatcaag
    15781 aggacgccac caattcgact agaaacattt aaaagtaaag aaataaggga aaaaagcatg
    15841 gtaataccat aaactactaa gacagctcct cgatgagtaa agcccattga taagagtcga
    15901 tgatgcaggt gcatcttatc cggctcgtag aatttttgac ctgataaact acgtcgaata
    15961 atagccacga tggtatccat aatgggtaca ccaagaataa taacaggtgt caccacagcc
    16021 acagccgttg aatttttcaa tccttgaaga gacaaaaccc ctatcataaa gccaataaag
    16081 agggctcctg tgtcacccaa ataaatcata gctggatggt aattataagg aaaaaatcct
    16141 gcaatagcag aaatcaagac caaaatggtt aacgtcaaaa agaaatcctt ttgaggtaaa
    16201 aagaaataag atacaatagc catggtcact aaactaataa tagagacccc actaaccaaa
    16261 ccatccaaac cgtcaatcaa gttaatagca ttagtgatgg aaacaatcca caggactgtt
    16321 aagaataagg ttaagaaagg accaaaaact aacaacggcc ctccaaaagg aattttgaag
    16381 ctatcaaatt taaagtcggt aaaagcccag acaatcactg caccaattag aataccaaac
    16441 atctttaatt taggacttaa ctcatacaaa tcatctaaaa aaccagtaag ggtaattact
    16501 gtagcaccaa tcacgacagg taaaatataa ctgaagtagg tctgaccaaa aaacatggcg
    16561 cctttagaag caatcggaat aagtcccaaa cttgctacta aaaaagacat aaaaatagct
    16621 aatccaccac tggttggcat cggaacctta ttgacccgtc tggcattggg attgtctact
    16681 gcacccacac gaaaggctaa aaagcgaaca agaggggtta agaataagga cattaacaaa
    16741 gcccctatca gaacaaggac ataatctatt gtgaatgaaa acatactatt ttatcccaac
    16801 tcaatctttt gtaattgctc aacagcacca tcaagcatca attgtaagcc atgctcttgt
    16861 aaataagctc ttgtttttga tccagggttt gcatgctcaa tcaatctcgc atacatgaca
    16921 ttcgcaaaat aagatggttg ttgctgaaca tctaataaaa tagtcatatg gtagcagttg
    16981 ctccccttat ataactctga agcttctatc gaaaaatcaa tcgttttagc aaaagccact
    17041 gcctctgtaa tcgttgaaaa atccaataca taatggacat agtctaaagg ttctgactca
    17101 tgattagttg atggatcagc cgcctcagac tgattagcta gagtggcttc aacaacatct
    17161 tccattatct cttcaatttt ttccaatttt tcatgagctt tgacatctcc cttttcacgc
    17221 atggattgct ccaagctctt gaaaaaatct tccggagtca tttgggacat atcaccaaac
    17281 tctgctaaat cttcaagatt aatatcttta tttatctcag atttggtaac aaaaacatct
    17341 agacggtcct tgcgtggagt cactcgaaaa ctaagcatac cactatcttt aaaattatct
    17401 ggaagatcga gttcgtccat cacagaatag aaaaactctt ctgttttttc ttgaggaatc
    17461 aagaaatctt tcaactccat tcctctttct tctaaatcgt ccatactaat tgttattttt
    17521 agcgttgtct cgctaatttg tttcatttcc attctcaata cctcgcacgc gtagtcattt
    17581 tattatacta gaaatgctgt aatttcgcaa tttatgacta actcctcttc tacaaaagga
    17641 aatttaaaaa gcgacagtcc ccaaggtctg tcgcaacatc ctaaacgata tgtaagttta
    17701 aaaaacaaat ttaaagaagc tataaataag taaaaggctt cctaacacaa tacggtattt
    17761 cccaaaaatg gtgaaatcgt gtttcttaac ataatctgtc aagaacctaa tcgccaataa
    17821 actaaccaca aaagcggtca agctagccac taaaagaata aggacttgtg caaaatcaag
    17881 gtgatggcca tcaaggaaaa atttcacagc ctttaatcca ctatatccaa acatggtagg
    17941 aatggccaaa aagaaggtga aatcagcggc cactgttcga ctagttccta aaataatagc
    18001 tcctaagatg gtagcccctg atcgactagt accaggcaca atacttaaga cttgaaaaca
    18061 accaatgaag aaagctgttt tgtaagacat tctagctaat tcagtgacgg caggttcttg
    18121 ttgagcattt cgtttttcaa tccagataaa gacaatcccg tagacgatta aagcgatggc
    18181 aatcggaacc ataaaataaa aatgtgcttc aaaccaatta tcaagaggaa ccgctattaa
    18241 aatagaagga atacacgcaa tcaccacttt tagccataat tgccaggtaa gctgtacttc
    18301 tcttgctgtt ttcccaggtt gaaagggatt gagacgttca aaataaatca acataacagc
    18361 gataatcgcc cctaattgaa taacgatatt aaacatttct ataaaagcct tatcctgatt
    18421 tagtcggata aattcctgca ctaaaatgag gtgaccagtg cttgaaactg gtaaccattc
    18481 tgtgattccc tcaatgatgc caaagaaaat ggcttttagc aattcgataa ttaacatgtt
    18541 ttctccttat taaccactct tattgtgatt ttctgaactg tgattaatgc caagcagctt
    18601 ttttaaaagg caccgccgcc gcctcctccg ccaccgccag agaagccgcc accaccacta
    18661 atcccgcctc cggaagagac tgagaaattt gaggaagttg tagctgaaga caagctagac
    18721 acaaaggttg gtgtcgtagc atacattacc attgataatt cacctggtcg aacagcttgg
    18781 taaacctcag gtaaggcaat acgatggact ttcaaatagc gttccacttt cttagcgtaa
    18841 ccaaataagg tggcataaac caaaacacgg ttccaaacaa ccaaaccttc aatagcaaca
    18901 tcctcaaatt tgtcaatgtc tcgtatcatg tttttaaagc tctgccattg atgtaaccga
    18961 acacccccct caggtgtttc aatacccaat ttcttgtatt gatctaactt caggctaatg
    19021 taaaagccaa ggcacatcgt tagcaccatt aaagcaaggt aaatgagggc taacccactt
    19081 tctttaatag ccaagtaaat caataaacca ctatttagaa taagcaacaa acaacctaat
    19141 ccctggacac tattgctttt tcgtttctct gccggggtca tttgacgata agtatctggt
    19201 aagtttaact ttttgatagt ttctaggaca ttgtttgtaa tagctgccga cgcttttttc
    19261 atcgccttaa tcacctgctc agacgattga cggacttctt gctcgagctt tttacctttg
    19321 tacgttttct ttaattgttt aatggtatca gcatcataat ggtattgact aaacaattga
    19381 tccaccggca atgtcacctt gtttccaaaa gccatatcta agaaggcagc ttcctcatct
    19441 gtcacacgat ctaactgact gatttcaaga taagctttcc cttcttcttt cgttaataaa
    19501 agcacctttt ggtcgatcag atccaacaag gtagcttgaa caagggcctc aaaggtcact
    19561 cctttaggga tcaataattt ctggctttct gatgctgtag gggataaata ggcaaaactc
    19621 tgtccataaa tcgcttgtgt caacacaaga ggcgaaagat cttcagggac ttcgtaactg
    19681 tgatctgtat ggttagccaa atgataacga ttgaattgtt tctttaatct tgtaaactgt
    19741 attaactgcg aaagaagaaa acctacctct accagaggaa tgactttgcc aaatagcagc
    19801 tgtaacaagg tccttcgtct ggaaatctta gtttctaacg ctacaatttt attcttttta
    19861 ctcgttgaaa catcaactgg ctcttttccc aataatgctt ttttatccca ataagcatgc
    19921 aattccaatt gccctgagac attcttggca ttaatctgat agcgactgtt accttctttt
    19981 aacacttgag gtttcttttg gtaatatcct ctgtgagccc atagattaga atcctgaata
    20041 tcagttgggg tagtgacggt caaactcacc ttttctaatg ttttgtccca atcactaatc
    20101 ggtgtccaat tcagctctgc cacgtcttga taagctgtta aaaggtggtg cagttgccag
    20161 ataaccttga cgtcaacctt atcaccagct tggccagcat tataaagttt taaacgatag
    20221 ccatctccaa ggtcactaaa ctcttgacta acaggtacct gttgaccatt ctgatatacc
    20281 tcaactttag gcttttggtc aatagcaaag cccgctggca aatgacctat ccggcccagc
    20341 gaaatatact ggccgttata agaagtgtca aattgatagg ttactttttg ctcaaaccga
    20401 gcagtatttt cttttgataa cagtaactga ccttcatagt tggtgatgct atagtctaca
    20461 tcagctgctt ttattcgtat ccctaaaaga ctgaagcaga gcacaagcgt catcaaaatt
    20521 tttttcatgg caacatcctc tttctgccct cattttacca tattttaagg agatgacaaa
    20581 acctaaacca agtccttcat cttattttta ctcattattt tgaatatttt tccatatttc
    20641 aacctattca ctgataatat attgaaatag gatgcaaatt gctgtaaaat aggtctgaat
    20701 actatttttg aaacaggaga cctatatgaa aaagctaatc cttagctgtt tggtcgcctt
    20761 ggcccttctg tttggaggaa tgagccgggc tcaagcaaac caatatttaa gagtcggaat
    20821 ggaagcagcc tatgctcctt ttaactggac tcaagatgac gcttcaaacg gggctgtccc
    20881 tattgaggga actagccaat acgccaacgg ttacgatgtc caagtcgcta aaaaaatcgc
    20941 taaagctatg aacaaagaac ttttagtcgt taagacctct tggaccggtt taattccagc
    21001 attaacttct ggaaaaatcg atatgatcgc tgctggtatg agtcctacca aagagcgtag
    21061 aaacgaaatt agcttctcaa acagctacta cactagccaa cctgttctag tcgtaactgc
    21121 taatggcaaa tatgctgagg caacaagcct caaggatttt tctggagcta aagtaactgc
    21181 ccagcaaggc gtttggcatg tcaatctctt aactcaacta aaaggtgcta agttacaaac
    21241 accaatggga gatttctctc aaatgcgaca agcccttact tcgggtgcta tcgatgccta
    21301 tatttctgaa cggcctgaag ccatgactgc tgaagctgct gatagccgtt tgaaaatgat
    21361 cactcttaaa aaagggtttg ctgttgctga atcagatgct gctatcgctg tcggaatgaa
    21421 aaaaaatgac gatcgtatgg caactgtcaa ccaagtgctt gaaggatttt ctcaaacgga
    21481 tcgtatggcc ctgatggatg atatggttac caaacaaccc gtggaaaaga aagccgaaga
    21541 tgctatagca tcatttctag gccaaatgtg ggctattttt aaaggtaact ggaagcaatt
    21601 cttacgtgga actggaatga cccttctgat ttccatggtc ggaaccatta caggtctctt
    21661 tattggatta ttaatcggta ttttccgtac agctcctaaa gctaagcata aagtagccgc
    21721 cttgggacaa aaactctttg gttggttact cactatttat atcgaaatct tccgtgggac
    21781 acctatgatt gttcaatcta tggttatcta ctacggaaca gcgcaagcct ttggtatttc
    21841 gatcgaccgt accctagcgg ctatttttat cgtatctatc aatacgggtg cctatatgag
    21901 tgaaattgtt cgcggtggta ttttcgctgt cgacaaaggt caattcgaag cagcaactgc
    21961 tcttggcttt actcacggac aaaccatgcg taaaatcgtg ctaccacaag ttgttcgcaa
    22021 cattttacca gcaacaggta atgagtttgt catcaatatc aaagatactt ctgttttgaa
    22081 tgttatctct gttgtggaac tttacttctc aggtaatacc gtagccacac aaacctacca
    22141 atatttccaa acctttacga ttatcgccat tatctacttt gttcttacct tcacggtgac
    22201 acgtattctt cgttatattg aacgccgttt cgatgccgat acttacacca ctggagcaaa
    22261 ccaaatgcag attgcggagg tctcaaatgt ctaactcaat tattgaaatc aaaaacctca
    22321 aaaaatctta cggcagcaat gaagtactca aagatatctc cctttctgtt aacaagggag
    22381 aagtgatttc cattatcggt tcttctggtt ctggaaaatc aaccctcctg cgctcgatca
    22441 atcttttgga agagccaagt gccggtcaaa tcctctttca tggtgaagat gtccttgctg
    22501 aacactacaa cttgactcac taccgtgaaa aactaggcat ggttttccaa tcctttaact
    22561 tgtttgaaaa cctaaatgta ttggaaaatg ctatcgtcgc tcaaaccacc gtcctcaaaa
    22621 gagaccgtgc acaagccgaa caaatcgcta aagaaaacct caatgcggtt ggtatgacag
    22681 aacaatactg gcaagccaaa ccaaaacaat tatcaggggg gcaaaaacaa cgggttgcca
    22741 ttgccagagc cttatctgtc aatccagaag ccatgctctt tgatgaacca acatcagctc
    22801 ttgatcctga aatggttggt gaggtcctta aaaccatgca agatttggca aaatcagggt
    22861 tgaccatgat tattgttacc catgaaatgg aatttgctcg tgatgtttct gaccgtatca
    22921 tcttcatgga taagggattg attgctgaag aaggaagtcc tcaacaaatt ttcgagaatc
    22981 ctacacaaga tcgtaccaaa gaatttttac aacgcttctt aaaataagat aaaggatcca
    23041 actatttcta tgccagttgg gtcttttttc aattcaaaaa gaatttgtca taaaatactt
    23101 taccagttaa ctattttatg ctatacttat ttt
//
LOCUS       DAUGOH010000026        22479 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUGOH010000026 DAUGOH010000000
VERSION     DAUGOH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22479
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.026"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(115..2130)
                     /gene="recG"
                     /locus_tag="VH957_001159"
     CDS             complement(115..2130)
                     /gene="recG"
                     /locus_tag="VH957_001159"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEQ8559074.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPDTLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENKSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAALKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     HKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAKNIRKKEIYD"
     gene            complement(2505..3959)
                     /locus_tag="VH957_001160"
     CDS             complement(2505..3959)
                     /locus_tag="VH957_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559075.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVPTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQNLLALTDEQQQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(3896..4576)
                     /locus_tag="VH957_001161"
     CDS             complement(3896..4576)
                     /locus_tag="VH957_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8559076.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(4573..5166)
                     /locus_tag="VH957_001162"
     CDS             complement(4573..5166)
                     /locus_tag="VH957_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEQ8559077.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKAAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSVFAHYLLKKHFIKSGLLS"
     gene            complement(5163..6833)
                     /locus_tag="VH957_001163"
     CDS             complement(5163..6833)
                     /locus_tag="VH957_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559078.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGIYHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LYEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            complement(6826..8589)
                     /locus_tag="VH957_001164"
     CDS             complement(6826..8589)
                     /locus_tag="VH957_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEQ8559079.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(8586..9422)
                     /locus_tag="VH957_001165"
     CDS             complement(8586..9422)
                     /locus_tag="VH957_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559080.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQIWLEQEELATISIKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGQLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNGIRTQRRDRNK
                     NR"
     gene            complement(9419..10441)
                     /locus_tag="VH957_001166"
     CDS             complement(9419..10441)
                     /locus_tag="VH957_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8559081.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYEAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYALAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(10443..11327)
                     /gene="isdE"
                     /locus_tag="VH957_001167"
     CDS             complement(10443..11327)
                     /gene="isdE"
                     /locus_tag="VH957_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEQ8559082.1"
                     /translation="MIKRCKGIGLVLMAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSVNPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHP"
     gene            complement(11311..12186)
                     /locus_tag="VH957_001168"
     CDS             complement(11311..12186)
                     /locus_tag="VH957_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEQ8559083.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTNLVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDSQKPVDTKLGESQDEPHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            complement(12383..16210)
                     /gene="shr"
                     /locus_tag="VH957_001169"
     CDS             complement(12383..16210)
                     /gene="shr"
                     /locus_tag="VH957_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ8559084.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKPVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDITITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVPYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKVTGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(16701..18230)
                     /locus_tag="VH957_001170"
     CDS             complement(16701..18230)
                     /locus_tag="VH957_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8559085.1"
                     /translation="MDKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSKQLPEARTPI
                     QSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKS
                     TGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAF
                     DLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFT
                     DTTGSGKRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLG
                     YQASSYAWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKVGYALSKTPKVGYAISFAP
                     GQAGADGTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSK
                     N"
     gene            complement(18317..19417)
                     /locus_tag="VH957_001171"
     CDS             complement(18317..19417)
                     /locus_tag="VH957_001171"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEQ8559086.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(19414..19770)
                     /locus_tag="VH957_001172"
     CDS             complement(19414..19770)
                     /locus_tag="VH957_001172"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEQ8559087.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(19886..22405)
                     /gene="secA"
                     /locus_tag="VH957_001173"
     CDS             complement(19886..22405)
                     /gene="secA"
                     /locus_tag="VH957_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEQ8559088.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVNEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAVDAIVTFARTSLVPEESISAKELRGLKDE
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
BASE COUNT         6923 a         4658 c         3855 g         7043 t
ORIGIN      
        1 cagtctcatc gtaaagcata agtaaaaaag gccagaaaca gtgacctctt tatactttat
       61 aacagtttat ctcaaaacta actaaatatt tgtaaaacaa cgacttggtt taagttaatc
      121 ataaatttct ttttttctaa tattttttgc tactaactgc cactgttttt catatatcca
      181 gttaggatca gaaacaatcg ctgcagaaac tttgcgtgct tcttctaaaa taggataatc
      241 ctcaacgata tcagctactt gaaattctgg aattccagac tgacgagtac caaagatttc
      301 accagaacca cgcattttta aatccgactc agccaaaacg aaaccatctg tcgtttctgt
      361 catgattgtc attcgttttt tccccgaatc cgttttggga ttagccacta aaacagcgta
      421 tgattgttta tgtccacgac caacacgccc acgaagttga tgtaactgac ttagtccaaa
      481 acgatcggca tccataataa tcatgatcgt tgcatttggg acatttaccc ctacttcaat
      541 aactgttgtg gatactaaaa tatgactttt tttatccttg aaatcttgca ttatggcatc
      601 tttttcatca tttttcatac gtccatgtac aagagcaacc ttagcaattc cttcaaaata
      661 agtagataat tcagcatgca atgctactgc attctttaaa tctaaagctt ctgattcttc
      721 aatcaacggt gaaatgacat acacttgagc atctttttgc aattcacctt ttacccattc
      781 caacacagtc cctagctgct cgtgtttcac ccagcgtgtc ataataggtt tacgaccggc
      841 aggtaattca tcaataacag aaacatccat ttctccaaaa gctgtgattg ctagagttcg
      901 gggaattggg gtggctgtca tcattaaaac atcaggattt tctccctttt cacggaaaat
      961 tctacgctgt ttaacaccaa aacgatgttg ctcgtctgta atgacaagcc ccagtttatg
     1021 gtactgtacc gagtcttgga taagagcatg agttcctaca atcatatcaa ccgagccatt
     1081 tgcaatagct gctaaaaccg tacgcttgag agcggctttc atacccgaag ttaatatagc
     1141 aattgataga tctggaaata actcttgcag actaatgtag tgttgttcag ctaggatttc
     1201 cgttggaacc atcaaagccg attgaaaacc tgctgtataa gctgcataca ttgatagacc
     1261 agcaatgact gtctttcctg atcctacatc tccttgcaat aaacgattca tatgagctcc
     1321 cgatgacata tcagataata tgtcatctaa agagcgcttt tgagcattcg ttagaataaa
     1381 aggtaaagag gaaatctttg tctccatagc atgtttacta taaagaatag gcaaaccatt
     1441 tgtttcagat ttattttcgg ctttcaaaac ttgaaggttc atttgaaagt aaaataattc
     1501 ttcaaattta atccgacgga gcgcttgctt atactctgtg atatcttttg ggaaatgcat
     1561 agctaaacaa gcctgactac gacccatcaa tcggtatttt tccaataaag tatctggtaa
     1621 attttccttc aattccaaat gcgcatcgat ttcaaaagct gacttaatag ctttaatcaa
     1681 agtagactgt gaaattccct gagctacgcg ataaacaggt tgcatgtcat cttcaacttg
     1741 agctaaaact ttcatcccag taatagctga tttagtggca tcccatttac caaaaacagc
     1801 tacctcttga ccaagttcta ttttatcagc taaatagggt tgattaaaaa aactaacatt
     1861 taagacagct tccccttgac gcaatttgaa acttaaacgg ttacgtttaa aaccataata
     1921 ttgtacatta gctggagtaa cgactaagcc tgtaatgact gctttttcac catccactaa
     1981 atcaaaaaca gattttgatt taaaatcttc atagcgaaac ggataataaa gcagtaaatc
     2041 ttctactgta taaatatcta atttctgaaa tttttctgct gattttggtc caaatccctt
     2101 taagttggac ataggagctg ttaatatcat tatctttttc ccttcacaaa aactcttgtc
     2161 agattgaaga caaagtttgt cgtgatactt tccttaggtg gtgcttacgg cagcgacgtt
     2221 ctttggaatt ccatgccttt atttttgagc ctgaggtctc aaaaatcccg agtggcgtca
     2281 atctcgtatt gacgccactc ttttaccaca gtaaaaagca tctgttttgg ctcactttgt
     2341 gtgtaaaaat cggaaaccga atgtcaaatc agcagagcta ttcatgcttt ttgagcataa
     2401 aactggggtt gtctacgttc tgactcttgt atctattata caagagttcc tatttatttt
     2461 cagataaaag ccttttagta cttttaaaca gttctagggg ctcgttaagg tagcatttga
     2521 taaatggtat cgcagacact acttagaagt tcttcatcat gtgaaatgag gatgacaacc
     2581 ttatgttggg tcttcagctg catgagaaga ttagctaaag ccttcatttg taacaaatca
     2641 agtccgctac ttggctcatc aaaaattaag atatctttat cagccaaaag actagcggca
     2701 atcatcactc tttgttgctc acctcctgac aaactagctg gatgacgttc taaaagagtt
     2761 gttaaagata accgctctat tacttctgtc gtccgtggat gtcgttcatg gcccaagttg
     2821 acttcctttg aaaccgattc tgcaaatagt tgcaaagaaa cttcttgtaa gacaatacta
     2881 gtctttgata aacgttgctt ggcagataaa ggtatgcctt gaaacttaat agttgctttt
     2941 ttatcgtcta agataccagc tatataataa actaattgcg attttccaag cccgtttgat
     3001 cctgtaatgc cagaaatact tcctgcagca aaactaagct gttcaataca tctaagtatt
     3061 ttgcttcccg ctctaactgt tagatgctca atacacaggc tatcatctgg gcgataatgt
     3121 tgactctcaa tcttaccagc taacacaggt tttaggtcag acaagtctaa gcgacgtagt
     3181 cccatatctt gctgttgttc atctgtcaag gctagcaaat tttgtgttgt taacttatct
     3241 gttaatctac catttttaaa gtagaaaaag ttatctgcca aatccatcaa gtaatgtaag
     3301 cgatgctcgg ctacaataat ggtttttcct gctgctttta attgggtaag ataggcttta
     3361 acagcagcta tgcctgcact atctaagtta gcagttggct catcaaaaag cataatatta
     3421 gtaccttgca taatggccgt tgcaatagca actctttgtt tttgccctcc tgacaatcca
     3481 aacatatcct tgttaaggag ctctgcaaaa gcaaaatctt ctgctaaagt ccaaagacgc
     3541 ttcatgataa cctttgcatc tagaccttga ttttcacagg gaaagaccag ttcgtgttgg
     3601 acttcgcgat agaaaaactg actggctgga ttttgaaaaa cagaggccac agatctagaa
     3661 aatgtttcaa cactgtctct gcctgcttgg caatcagcca catctagtct accttcatat
     3721 tttccagcat aataatcagg aattatgcca ttaagaagtt ttaaaaaggt agatttacct
     3781 gaaccagaag gtccacacaa aacaatgaat tgtccagagg caatttgaca agtcggtacc
     3841 tgacaagctg gatttttttg atcatgatag gtaaaaacaa gttgttctgc tgaaatcatt
     3901 gaagtatcgt gatgattatg ataacagtaa tccaaatctg caccccccaa tctttccatg
     3961 ttaagtgtga gctaaagcat tcactggtgc ctttgttgac tgctagccct ttagttagac
     4021 tagcgatagt tagttcttgg ctacttctta tcaaagataa aagcaatgga accattaaat
     4081 actccaagta ttgtttaggt ctgatcaaaa tagaccattt tgttaaaata atccccctga
     4141 ttgttaaaga gcgatgaata acacaacatt cttgtctaat cattggtatg aaacggcaca
     4201 taacggctaa ggtcaagagc cagacttctg ggaaatgcca tttgcgtaat ccatgaacca
     4261 attcgtagat ggtagttgtc ttaatagtaa ttaaacctgc tagtaaagaa gggaaaacta
     4321 accttcctgc tattgagaca aaactcaata agtggtcaag ataagaaggg aaaatcgata
     4381 gcgggattac agatagaccg atcattaaca gataaacaac cgccaacttg aacgctagct
     4441 ttttcttatt taaagcagac aaaagtaata agagaaaaat aacaattata aattctaaaa
     4501 agccatcaac acgaaaaaag aagcaggcat tggcaagtac caacaaaagc agtttggtgc
     4561 gaacatcaag cctcatgata acaatcctga tttgataaaa tgtttcttta gtaaataatg
     4621 tgcaaaaact gaccctaata aggctcctgc aagaacaatt cctacaaacc aaataacatg
     4681 ccctaaacta aaatcataca taatgcgatt gacataggtc atacttttac cgcgggctaa
     4741 caaactttca acataggcag ctttcaacaa ccacatcagc aaaatagggc cactattgac
     4801 aaaagcaaaa accatataag ataggtcatt aaaaaacctt gacttgtatt ttcctaaaga
     4861 agcaataata tccgctatta aaccgaaaat aatgctggga aacatcgcgg caaaaaagtg
     4921 accactaagg aagaaaaaac ctcccatcat caatcctaat aatgttattg gcccaaatgt
     4981 ttgcaattta gcaatcaaaa gaaaataaat tgttcccccc agtaaagctg caaaggcagg
     5041 ggcatataac atatttcctg agcgatcaaa aaagatgtta ataaacgtgc ctagaccaac
     5101 acaaataaag tagagcgcgg caaatgcgcc tgttatcata atatctttta ttgttaactg
     5161 tttcattttt tattcacctc ttttaggaaa ccatttttta cgcaaaatag atgatcagca
     5221 caagctaggg ttgatggcct gtgagaaatt aagaagacca atccttgaca atgtgtttta
     5281 attaaatcaa gcaagatagc ttcatataga gaatctaaat ttgacgtggg ttcatcaaaa
     5341 atatagcaac tcgcatcttt caataaagct cgcatcaact ctaaacgttg accttctcca
     5401 gctgaaaaat cagaaggact cttgataatc gtatccaaac cttccttaca agctaacagt
     5461 ctgtctttca taccacaagc ctcagctaaa ttccaaatgg actcatctga aatatcttga
     5521 cggccaaagg taagattttc acggatagac tgttggaaaa gctgcgctgt ttgtggcaca
     5581 taagcaatag tatcttgtaa tttagcagca tttagtaagc aactattcct atcattaaga
     5641 aaaatatctc ctgtcttcca attataccat ttcataatta atttcaccaa agttgattta
     5701 ccagatcctg attcgccttt aatgccaata atcccctttt cttgaaaggt aactgataaa
     5761 tccttaaaaa ccagctcttg gcgctttgga taagcaaaac tgaggtcctc aaaagaaaca
     5821 ctccttaaac gatctatctg ttttgtgcct tcgtctacta tgacattttc gtctagaagg
     5881 tcaaaaatat ttcgagccgc attcatagca cgcttaaaac ctaatggcaa acgtcctagt
     5941 tctaaaaaag gagaaaacga agcagtgaaa gcaataaaag ttaataagcc tttatcaaat
     6001 gataagctgt catggtatat cccatcaaaa accatataag aaaatgctaa gatcattaag
     6061 ccaagccaga aaaaagtcaa tgccatttgc aaaaattggg cttgcgctac gttacgatca
     6121 agagcattta catgattact tttttttatt aatcgttcaa attgctcgtc taatacctga
     6181 aattgcaaaa gatctttgac tgatcgtaaa ctctctaaaa aataagacag gtaatctttt
     6241 cgaccttcat tttggctttt tagtaaaacc tgtaaaatat tagcaaaata aatgggtata
     6301 acaatggcta aacaagcata ggttgccaaa gctaataagg ctaactgcca actactttga
     6361 caaaagtacc agaacattaa acctgcagac aatattgctg tacaaatagg tgcgattgtg
     6421 tgggcaaaaa aaacttctaa tgcctcaata tcttctccaa tcattttaag caaataacca
     6481 ctgtcttgac tatccaagca agctggagaa agagctctta gtttcttaaa gatcaagttc
     6541 ctaaaagctg ctaaactatg aaaagcaaca aaatgaccaa aataatgctc tccataacga
     6601 acaaaacctc ttaaaaaggc tagagcaatc aaaagatata aagctaatat tggaatcact
     6661 tcttgtctaa tagctagtag tcctaaataa gctattccag ttggaatact taccgtgatg
     6721 acaaaaccca taacagcaaa gccaacagcc aagataatcc aaggtagaag agttttcatt
     6781 agggttaata aacgccaaac caggcttaag gtagatctgt taggtttagc cataaatact
     6841 tgcctccagt cttgcttgag tatcaactag gtgacgataa gttggttggt cccgataaag
     6901 gtcgcaaggt ttgcctaaac aagcaggctg ccctgtgttt aaaaagagta cttggttagc
     6961 tcctttcagt cgagacatct tatgagtaat cacaataact attgctgtct tagctaatct
     7021 cgttattaaa ttgtcaataa tacgttcatt ttctgcatct agactagatg ttgcctcatc
     7081 aaagatataa agagacctct tacttaatag agctcttgcg caaatcacct gttgcttttg
     7141 gcctggtgat aacaggttac cattttcacc aactattgtg tcaagaccat ctggtagcca
     7201 gttgatgaag cttaacaaac catgttgatc tatccaatct aagatttctt ttttagagag
     7261 atttgctgct aaccttaaat tatcgtaaat gctacggttc aataaggtag attggtccga
     7321 tacataaaga acctgctggt tgatagtttc ttgcgacaaa ttgtcactgt ctaaaccgtc
     7381 aaataaaata tgcccagtcg ttgcagactg gcgtttcaag aggagttgag ctagacttgt
     7441 ttttccttgt cctgacaccc ccgcgatagc tgttagttgg cccttcgtta atgtcatggt
     7501 aaccccacta agcactgttt ttttctcata agctaaagaa atattttgga tgtcaatctg
     7561 gttaaagttt attgctgttt tactcttgtt atctttcctt gctggaacac tatccaagaa
     7621 actaaagata cggtcagcca ttttggtatt catcatgacc aagtgcatgc cataaccctg
     7681 ctcacgaatc ggtgtaaaaa attctgtagc aatcaagaga aaaaagagga aattaaaaaa
     7741 agataactgg cctgttgcca aagcttgaac ggctaaaaaa cctgacaaac caattcccag
     7801 atacataact gcatccatat aaccaactgc ttgtaactga aagccaagca aagacatggt
     7861 agcctttcga aactgttctg ccttacccga aaattcttgc tcgtaacgtt ctgttgcttg
     7921 ataagaatac agtgtattaa gaccttttaa gtcatccata aataaattac caacatccat
     7981 ataagaagac caataatgac tcataatttg cttagaccgc ttttgcatag caacaattga
     8041 aagtggaatc agaggcagaa ctcctaaaaa gacaaggcct gccaatggat aaattaaaaa
     8101 gactagtatc ataatagttg tgcagttcca cttggttctc atagacaaag acaaatagta
     8161 accataataa gtatccaaac tatcaatccc ctgtgaagcc aacgttaaaa tatcagcatc
     8221 actggcatga gcatcaaatt gcccgtctaa atcaataaaa gcctcaaaga aagattgttt
     8281 gagtgaatct ctagcaaatt gtgaagcgat cccttgcagt tgcttgccta atatagcaag
     8341 aacaaagcct accacattta aaagtaggag taaacctgcc aagcgtccta aggcaatagc
     8401 atgacccaaa ataaaggtcg aaaacgtttt ggcaatgagg taaaaactga tcatcctcat
     8461 cacaaattgt aaccaagata aaaaggctga cacataaagc aaataccttt ttggtgcaat
     8521 tcgttcacgt aatcgtttta acagtctttt cctttttccc cttgatattg tatcttctgt
     8581 ttccatcatc tgttcttgtt cctatctctc ctttgagttc taataccatt ggtttcattg
     8641 accaatgaag tgaggacaaa ctgttgacca tttctctcaa caaagggcaa ttcaacacca
     8701 aagacatctc tgataaactg ttgatcaagg aggtctcttg gttgcccttg ggcataaagt
     8761 tgcccatctt tcagtccaat aagatggtct gaaagagaca aggcctgatt gatgtcatgt
     8821 aatactaaca caatcgttag gcctagctct tggttgattt tagtaatcag cttgagaatg
     8881 tcaagctggt acttaatatc caaataagtc gttggctcat ctaaaaaaat aatatctgta
     8941 tcctgggcaa gggccatggc aatccaaacc ctctgctgtt caccaccaga aaggtgttgg
     9001 atgtcacgat aaacataatc actcaaagcc gttacttcta aggcccaagc aaggcgttcc
     9061 tcatcttctt tggtagtagt tttaaaaaaa gaacgacggg caagcctagc catggctacc
     9121 aattcaccca ctaacaaacc ttcgaccact tgatggtatt ggtgtaccac tgccactttt
     9181 ttcgcaaaag ccttgataga aatcgttgct aattcttcct gctcaagcca aatctgccct
     9241 tgttttaacg gaaggttttt ggttaataat tgtaataagg ttgacttgcc actgccattt
     9301 gcccccataa tagtggtaat tttccctttt ggaatgctaa aggtcaggtc atctaaaaca
     9361 agtttttcct cataagcaaa ggaaaggttt tgcacctgaa tatgactact gttcttactc
     9421 atataatatc agacctcctt agcaggtaaa taaagtaagg cccgcctaca atactcatta
     9481 taatcgcagg gctaatttcc aatgggtaag caagacttct tcctaaagta tcggctagca
     9541 aaaagacaaa ggctccaagc aaagctgaaa aaggaattaa gatttggtgc ttacttccaa
     9601 ccagcaagcg gctcatatga gggacaatca agcctaggaa agaaaccact ccaacgatcg
     9661 aagtggctac cgaagccaat aaaacagcaa ccaaggaaat tcccaaccgt aacgctgtag
     9721 catcgattcc taaatgacga atcacctgat catctaaaag aagaaggtta caagtttttg
     9781 acaataacaa agctagtaac aagccaatga atgtataagg gaataaaacc cctacatcag
     9841 cccatgtttt ttgactaata tgacctgcta aaagagcatt gaccatggga ctagctgagg
     9901 tgaaaaagct ggttaaagca gttgataacc ccataaataa agcattaata gcaatccctg
     9961 ttagaataag ccgaatagga ttaagaccct tcttccatgc taaagcataa atcagcagga
    10021 aagacactcc gcctcctaaa aaggatacga ttggaccata cagcagcaac tgcggtagaa
    10081 gtaaactaga gactaaaacc ataaaactag caccactaca aatccctata atagcagggt
    10141 ctgaaatagg atttttcaac actgcttgaa aaagaactcc cgaaacagct atccctgctc
    10201 ctgctaataa agcaatgaca attcttggaa agcgcaaatc ataaatcaaa gccacttggg
    10261 ggtcataagc cacaaacagt cccttgacaa ttgcctcata agaaaccgcc aaaccaccaa
    10321 gggataaggc aataaccgcc aaaaatagga ggctgagaat taaaagaact aaataaagac
    10381 cacttctgaa acgtttttta gccaataggg attgatccct ttgtaaatct gatgctgtca
    10441 tgttacggat gatctcccac gtggtcaaaa agctgtgtta aggtgtccaa ggcttctggg
    10501 tagttcaatt tagcactcat gccaaacagg gtattgtcca aatcatagac tttcccttcc
    10561 ttgactgccg taaaatgttt ccaaatatca ttttcagcaa attctttgtc aaacatcact
    10621 tttaccttgt ctggaatggc gtgagctgtt cgtaaaatca agtcaggctc cttagctagc
    10681 atgtcttcag gattaactga tagaaattct ttctcatctg actgataaac attctcacca
    10741 cctgccaagt ccaaaagatt ccctacataa gattggttcg tcgccaccaa ataactacct
    10801 ggcaagccca taagaataag cactttaggc tttttcttcc ccttacgttt agcttggaaa
    10861 gcacgataat agtcctggta ttgctggcgc aattcttttg cttcttgttg acgttggaaa
    10921 aggttcccta aatcatcaat agactggtac atgccctcaa cacttcgtaa gttcaaaaaa
    10981 ccatactcag tatccaattt ttgatacttg ggttccaaat cttcttgtaa agaattggga
    11041 ctcaaaatcc aagttggttt caaagaagca atcaactcta tatcaggatt catgggtaaa
    11101 cccacacgct taacagcatc atagcgttta ggaagggtat ataatttact atcacaaacc
    11161 ccaacgaggt ctaaatttaa acggtcacag atatcaacca cagcaaccga agtggctaca
    11221 attctctgct gttcagtctc tttagccgtt ttagggtgct gattcacaca agctaccaaa
    11281 aagaaggcca ttaagactag accaattcct ttacatcgtt ttatcatttt ttttcctctt
    11341 tttccaaacc catacagcaa accctcctaa catcagaaaa aaagttggaa agtagtagat
    11401 catgattgat aagtcttttt tagaccgaaa cttatcttct ttttttaact ctaaagaagt
    11461 cgttaagccc atcttagaag gaagaatttt tttatctgat agactcttgt tatttgatga
    11521 gttggcttta ggcttattct gagttatcat agcacctgtg tgaggctcat cttgactttc
    11581 tcctagtttt gtatcaacag gcttttgact gtcttttact tcttgatttt gagaattgtc
    11641 tgtttcagta acaagctggg ccaacatatt acctgaatac ttttgtatta actctgaagc
    11701 tgacaggtaa aagaccactt ctctgcccat aggttcaaca aacatgcttc ctcgaatgat
    11761 actatttaca gtaggcaaac taatagcaat atctagtgtt gtcccattgg tatcagtacc
    11821 tttttgggtg atattgtaat caactgcctg aaagcttcca gttcctccag gttgtatcca
    11881 gaactgataa ttacccgaat aatcagctaa gctcatacga aaagtaagaa cgatctttcc
    11941 agcatcagat acttctagca tggcatcact atagacagtc ccttcaacca taccttgacc
    12001 aatatcaaag gaatgctccc ctccactatc ttctatctgc ccagatatcg ggtgacgata
    12061 atttctttga ataatacatc cataaatttg acctttatct gcatacacaa gatttgtcat
    12121 tgttgataaa cttatcatga acactactat tacctgcaac aattgcttta ttactacctt
    12181 tgtcatatgc tcctcttgtc tatcttttct taaacatctt atttcatttt ttaaatgatt
    12241 cccattttat aacatctcca aatgtgaaaa acacacctat cttgcgacca cttcaacctg
    12301 tatcaggaat cctgtcggaa ataggtatgt ttttagctct tgctgactag cttttttgtt
    12361 atttcacttg gtactaagtt tcttatttaa ataatgtctt tcgaccaata atgaatccca
    12421 gagctacgat cataaagcta gatagacctg caattaagtg ataacgagag ctactttctt
    12481 caccatttga ttgttgattg gaacgatgtt tcttatcaga ttttttagtc ttagtatctt
    12541 ttgccgtttt accttcaatt gatgtttgat ggtcacgcac taactgcttc aatttctctg
    12601 ccttatcagt atcatctgtc ttagaagttt cttgagttga ttggccggtt acttttttag
    12661 ccaggagatc agttaagtta gcaataccag tagctgctga aggaggactt gtaggtgttt
    12721 tttcttgttg acgattttga ggtcctttca actgatctgt tgaagttaga tggctatttt
    12781 cttgtggatt attagtttct ttgacaacct ttgccttctc tgttgtaagg cttgcccagt
    12841 ctaaacgcat aaaaacggtt tgaaggccag acccttttga aatggcatcc atgataggca
    12901 caaagacctg taatggcaca agtccgtctt tcttcgcttg ttcaatcaat ttcatacgca
    12961 gaacttttgg atagtttttt ccataacgat ctgccaatgg taggccagtt acatccgtga
    13021 aataagacac aacctctgcc ttttttgttc gaccaactgg tttaccagct aaatctcttt
    13081 ggtaaccatc tacgaaatag ctcaattcac caaggtagcc taacatttta ccaaccttta
    13141 tccctctaaa ctcaacctct aaatagggaa cacctttttt aactaccaaa gtcacccgat
    13201 gattaatagc cttgtttgac atggactcag atgctaagtc agtttttaac atgctggcat
    13261 ttaaatagta aataccatca cgcaattgtt tttgatttaa tgctctaagg ccgttctcaa
    13321 ctaaatcttt ctgatgtgaa tgtggtcctt tcgccacaag gatatcatta gatgtcaaat
    13381 agatatgttc tttttgagta gcaaatttct ttgttattaa agctttgcga atccgatatg
    13441 tacctggatc ttttaaagaa aactctcccg ttaagtcatc tttcggatca tttgagagaa
    13501 gcttttcgtc aaccgtcaca tactgtccat tggaagcttt tttttgcaac tgaatcacaa
    13561 tactccaatc gacttgcata tcattaagta aagaaacagt atctgaacct ttttcttgta
    13621 acaattgttg atattcttca atagacacta gttctttatc aatggcagaa tttgtttttt
    13681 gctcccaata atacaaatct aaaagactga aagcttgatg atattttatt ttttcgccat
    13741 ctaaggaagc ttcaagtttt gcaatatgtt tttgtggagt cagtttgtgt tgtccgataa
    13801 gagctcttac ttttggactc acacttttta tctgattgaa cttcacatct aaattaagcg
    13861 tttcaacatc tggaaatact gattcttcaa cctgagtaag caagttattg aaaaaatcaa
    13921 gttttgttaa ttggttattc tgtttaaata taccatttgg aagatttgaa atttcattag
    13981 ttgataaatc gagtacagat aatttaggaa gatttttaaa tgaaatatta tcaatacgag
    14041 taatatgatt tctacttgcc acaatagtgc ttaaggcgcg caatttttct attgtttttg
    14101 gcagtagcgc tagattattt tgagataagt cgataaaatt aagtgatgtt agaggctcta
    14161 gcgctttttc aggtatctcc tcaagactat tttctgcgaa acctaatgaa gtcagacgag
    14221 acaatccttc aaatgggtta tcacaaagtc ggccaatacg attcttggaa agatcaagtt
    14281 gctccaggtg atgaagcgac tggaatagtc ctccttcaag agagtgaata aagttacttg
    14341 ataagtagag ttctcttaat tgagcattgc ttttaaatgt atctttgtct agataagtta
    14401 aatgattact tcttaagtta agaaatcgaa gttgcttcat ttgactaaat aactcttttg
    14461 gaatttccgt aatttggttt ccatccagat gtagttctgt aatattttta gcatgtttca
    14521 ataaagaaat atcagttaac tcgtaatggt ctagacgcaa ctcacctcga atctgttcta
    14581 attctgtttt tgataattta ccatcgccgt ctaaatcttt gccaagttta actaaaactt
    14641 tttcaagacg ttcagtccca accccttttt ctttatcatc agtttctacc tgataaccac
    14701 tccagccttt ggtaacggtc ttactaaagg tcatgtcaag tttggtgtat ttgtcatagt
    14761 ggtttaaatc actttcttga cctcccatgg ctgataccaa aacagcacct ttgtgtaatt
    14821 tatccaaatc atcaataggc atggtaaatt cgcttcgaat atagctacca ttgatatctt
    14881 tttggccaac ttgtttacgc actgctgctg ggtaggtccc tttgctttca atagaaaagt
    14941 caatcaaaaa ttgtcccaaa gcagtattaa gcatggaaat ttccattgta ccatctgctt
    15001 taaccactaa tttggctctt ttatcaaaag caccttgaag catggaggac tcttctgagt
    15061 tttctttatt agctttaaag tttagcgtat aggttccttc tgtaagattg ttaatagaaa
    15121 cctcacctgc ttgataagac tcgatggtat cttttaacag tcgatgagta tcggcgagta
    15181 gcttactatc tttgatttct ttataagaat ccttgatgac ttgaagtttc tcagccagat
    15241 ctttgaccgc gtctttgttg ctttctttag caataatcgc atccgcttct ttgatagctt
    15301 tttccaaagt ggtgacatcc aactttgttg attgtctgtc ttcagcagtc acatgttgtt
    15361 tttgtttggc agatacaaaa tggatttgac catctttctt ggtaacggta atggtaatgt
    15421 cttcaaatcc ttttgaggat atcacgattg tattttctcc atctttgaaa gcttttgttc
    15481 caagatgaag ccctgtcata ttcgagaccc agccattagt atcttttaca gaatctgaaa
    15541 taagatcttt ataaactgta ccattgactg taaccttggt gatttgctga gtcaatgctt
    15601 ttatctgttt gttatcagaa taacgatcaa tttctggaaa taaaattgca ccatcttctt
    15661 gactcaattt tgttattaat gacaagttag cagtattttt cccagattta acaacttttt
    15721 gtgtgccttg gttttgtggc actggtttat cactgagcac atcttttttt aatgaatcct
    15781 gatgatctgt tgttcctaat ttttgagctg aaataaacgt cactttatcg ccctttttaa
    15841 taaaggtaat taggatatca ccatcttttt tattaacaat agtcaattca tgcttaccgt
    15901 ctttaataag gttagcattg atcttaatcc cttggtagtt aatatcaaag gttcgctcgc
    15961 cttccaggct tttttcatag acatcattat caacaataac cttttcaata tgtttataat
    16021 actcttttcc agctgattga ctagcgtaag ggcctatctc ttcaactaaa agtcgattat
    16081 cctgagttaa agctactgtt gtcacgagtt gtgactgaac taaaggctct tgtgatttta
    16141 cagtttgagt agcctgaatg agaacaaggg cagatattgc cacaaacgca catttgctga
    16201 tttttttcat tttcaatcaa ctttctaaaa atttttatga ataagctaac ttttttatta
    16261 actgaactta atctatcact ttgtgattat tttgtcaaga ttgtttccaa tggtccaatt
    16321 gtctgttaaa tagctccact atgtgagcta agacactagt aataagcctg gattgataat
    16381 gaggatatct ctgataaaag aattcctcta caacactatt actgagataa agctagcctt
    16441 aggatagtta ttactaaggc tgattcaatc attacttcat tcacaaaaca tgtaacacgt
    16501 tataagctcc ataattgtgt taggagacaa catgagatgt cactactgca tattcatcac
    16561 aataaaaaaa agacaatagc cctaatcgtg ctattgtctc aaaatcattt atttacttga
    16621 aactttatcg tgttacacca acagtttaaa aggcctaact cccgctaaga aaattaagcc
    16681 ttaagaaaag tcattagtta ttagttttta ctcttgccaa taacatatgt tagctgttca
    16741 gcctgctgag ctgtaaaggt acgataagaa atcttgccta agccgataca gttagactct
    16801 gaaataagaa tagacccatc ttttctaaca tcttctacaa ttgatacgtg gccataagtg
    16861 ccatcagcgc ccgcttgccc tggtgcaaat gaaatagcat aacctacttt tggagtcttt
    16921 gaaagggcat accctacttt atacttccaa tctccaccat ttcccataaa aggatcaaat
    16981 tggtaaccca attctttggc gcgattatac acataccaag tgcattgtcc ccaagcataa
    17041 ctcgaagctt gataacccaa gacatcataa ctcttagaga gcttataacc tgctggcaca
    17101 gatgcaaaac tagctgatga ctgcactttc aattcggctg gaatagctgg tgtgccacca
    17161 tggtcatcaa tccacttatc caggtcttcc ataatttgtg cgcgacgttt accactacca
    17221 gtagtatcag taaaataaac acccccgtca cttgcaaagt ttaattgacc tcgtgaaaac
    17281 ttagccgctt ttaaatcttg aagtgcaaaa ttgctatttt tgtttttaat aatggtgtct
    17341 tgtgtcattt tgacaatagc actatcatca ttaaacttac ttgcttgagt cggatctaga
    17401 tcaaaagctg catagccaaa catattagct ccaagcaaag ttgcaatccc ttgagttcct
    17461 aaagaactct cagacatcgc aatagctacg atagctcgaa catccagccc acttttcttt
    17521 tcccattgca atagcttctc accattaata cgtgtgctgt cataggcaat gcctgttgat
    17581 tttaagtaac tatcaatctg gtcagcttta ataccataac ggcgagataa aagatggtgg
    17641 gtataggcat ttttaccact ccaatgctct acatatgccg catatgtgtt gacagaaggg
    17701 atatctatct cactcaaatc taaatctgat acgtaaggtg acaacgactg aatgggagtt
    17761 cttgcctctg gcagttgttt cgacaatgaa gaagcaggtg ccgtatcaac tttagatggt
    17821 gatggtttgg gctgatcagt cggttttggc tggtcagtcg gtttcgaatg atcagttgat
    17881 ttcgaatgat cagttgattt atcatctacc tggttttctg cttctgcctt gttgtccgaa
    17941 gaacctacag cagactgact agaatcgctt ctttttttat catccgcgtt aacaagacta
    18001 ttagagtttg tttctgcaga agcatcaagg ggaccttggt cagttttatc tgatgttgta
    18061 ggtgctgcat ttttattatt ttcctctttt gaagaagaat cactggtttc atttgtagtt
    18121 gctttatgcg tctcaagcat tacatcttga gccaacactg tcatgctttc tgctgtcggg
    18181 gctaagagac ttagtagcat ggcaactctt aatagtttgt ttttatccat atattaatta
    18241 gtcacttctt tctaatgtcc tcactttatt ataacattaa agataagcac aatgcaatta
    18301 tttttacatg attttcttaa tatatccgag gaatacggtc acttaaaagg catagaactt
    18361 cataattgat tgtattacgg taatttgcga tatctgttgt agaaatattt ttttgctgat
    18421 tgctgccaat caaagtgact tttgttccta aaggatatgc tttgggaagt cgtatggtca
    18481 gttgatccat cgatacacgc cctataattt cacagaattg tccatcaact aacaccgaaa
    18541 agccttgcat gttcctggtc cagccatctg cataaccgat tgggacggtc cctacatatt
    18601 cagacttttt ggcagtataa gtagctccat aaccgactgt atcaccagct gaaatcatct
    18661 tgacatgcac taagctagat tctagagata aagcctcttg cagtggaaac ggtaagctta
    18721 gatcagaacc acttggattc aaaccataac tgacaattcc taaacgaaca gcattaaaaa
    18781 tggtatcact atgccagata cttgtggctg aattactagc atgtactaaa cgaggcttat
    18841 cctcaagtcc agctatcagc tttttaaaaa actgtaactg ctggttaaat ttagtatcat
    18901 ctgcctcatc agctgtggca aaatgagtga aaataccttc tacatcagca cccaactctt
    18961 ttagactatc aatcaataaa ttgacttctt ttgaagaacg aagcccgatc cgtcccatac
    19021 cagaatcaac ttttacatga acttttaagc cttgacattc ttttttctcc agtctagcta
    19081 aagctatcca gtctaaacta gcgattgtaa cagtaatagc attagcgact gctaactcta
    19141 attcatttgg caggaggact ccaagaatta aaatctcttt atcaatacct gcttgacgta
    19201 attgcaaagc ctcatcaaga tttgacacac agtacccatc cacttgaggt aggagtgctt
    19261 ttgacacctg gacagcacca tgaccataag catcagcctt gacaactgca tacgttttta
    19321 cccctagtgg aatatgcttt tgaacactgg caacattctc cttaatagct tgtaaattga
    19381 cccttgcaac tgttgggcga tggaaacttg aaatcatttt ttatcctcca aaataacact
    19441 agcctgtaca taattgccac tatgtgagat gctaataaaa ctatttcctt taaacggaga
    19501 ttttgtcaga atgggacatc ctctaacatc atttaaaatc tcaatatctt gaaaggttaa
    19561 ccgcccaata cctgtcccta tagccttagc aaaagcttcc ttacctgacc agcgtcctgc
    19621 caaatagctg agtcgacgtt tgtaagggaa actctcaaaa atagccaatt cctgctcagt
    19681 taaaattttt tgagcaaagc gaggatttct ttgataaact ttttcaatag ctgaaatctc
    19741 ttgtaagtct attccatgtc caacaatcat tactttccac caaaccttat ttcatcttaa
    19801 tgttagaaga tttaaacagt gagaagctga gaattattct cagcttcttt ctatatacct
    19861 aactttgtcc tgttgtgtct cgttcttatg agaaggattt acgaccgtga caatttttga
    19921 attttttgcc tgaaccacat ggacaagctt cgttacgctc cactttgggt aaatcatcgg
    19981 tgttagctga ctgctgcgat tggatgtttt gaggtgctgc tgttgtggca cgttgacttg
    20041 cacgttcacg ttcttgttcg tgaatttgtg ctttcatcat ggtacgtgtt acatcaaact
    20101 cgatagcacc aatcatatct tggaacatct tgaaaccttc tgcttggtat tccaccacag
    20161 ggttattttg agcataccct cgaagtccaa cagcattacg aagttgatct aaggcatcaa
    20221 tgtgttcagt ccatttgtta tccacaatca tcaaaatgag tactttttgg aattcaataa
    20281 tagcttcttg atcacgaagt tttgatagtt gctggtcgta gatagcaagc gctctttgat
    20341 aaagcttctc tttgatttgt tcgtctttta aaccacgtaa ctctttagca ctgatagact
    20401 cttctggaac aagtgacgtg cgtgcaaagg tcacaatggc atccacagca tccttacgat
    20461 tgctacgtgc atgagcatct acagcacggt cgatagtacg cttgatcata gctttaattt
    20521 ctgggccaag atctcgatta gcagttatga catcacgacg gttagcatag ataatttcac
    20581 gctgttcacg catcacatca tcgtattgta agacctgttt acgggtatcg tagttatttc
    20641 cttcaacccg tttttgagca gattccactt gacgccctaa catacctgat ttaataacag
    20701 tgtcttcttc atctagtttc atccgatcca aaaaggcttt tatacgatca gagccgaaac
    20761 gtctcatcaa atcatcttct aatgaaagat agaattggga ttcacctgga tctccttgac
    20821 gacctgaacg tccacgaagc tggttatcga tacgacggct ttcatgacgc tctgtaccaa
    20881 tgacacataa cccaccaagt tcacgaacac cttcaccaag cttgatatca gtaccacgac
    20941 cagccatgtt agttgcgatt gtaacagcac cacgttgccc agcattcata atgatttgag
    21001 cttctttaaa gtgattttta gcattcaaaa cctcatgagg aatccctgct tcaaccagct
    21061 tgcgtgaaat caaatcacta gtttcaacag caaccgtacc tacaaggata ggttgtcctt
    21121 ttgcatgacg cgttttaacg tcttccacaa ctgctctaaa ctttgattct aaggtcgggt
    21181 aaagcaaatc agtgtgatca atacgggcaa ttggacgatt ggttggaatt ggaataatac
    21241 gcatgttata aacttcgcga aattcttctt cctcggtctt cgcagtacca gtcatacctg
    21301 ccaatttttt gtacatacga aacatatttt ggtaggtgat tgaggcgctg gtttttgatt
    21361 cttcctgaat acgaacgcct tcttttgcct caatagcttg gtgcaagccg tctgagaagc
    21421 gacgcccttc catcgtacga cctgtaaatt ggtcaacaat aagaatctca ccatcttcgt
    21481 tgaccacata atcgatatct aacaacataa tatagtttgc acgaagggcg ttgtctataa
    21541 agtgagtcaa ggctacattt tcaatatcgt aaagattgct caagttaaaa taactctcag
    21601 ctttatcaat acctgaatcg cttaatccaa tcgttttagt gggcacatca ataacataat
    21661 ccactgacgt cagagttttt acaaacatgt cagcacgaat atacaattga ttggtttcag
    21721 agctaacagc accagaaaca attaaaggtg tccttgcctc gtcaattaag actgagtcca
    21781 cttcatcaac caaggcaaaa ttgagtgggc gttgtaccat gtcttcctgg cgaacaacca
    21841 tgttgtcacg aaggtaatca aaaccgactt cagagttggt tgagtaagta atatcacaat
    21901 tataagcttc acgtttttca gcaggagact tagcagctag gttgatccca actgaaagac
    21961 ctaaccagct atacacttca cccatttcgg tagcgtcacg cgttgaaaga tactcattaa
    22021 cagtaataac gtgaacaccc tcaccagcaa tagcattgag ataaactggc atggtggctg
    22081 taagggtttt tccttcacca gtacgcattt cagggacatc cccgttatga agaacaattc
    22141 ctcccataat ttgaacacga taagggaaca agcccaacac acgttttgct gcttcacgaa
    22201 caactgcgaa agcttcaggt aatagttgtt cgagggtctc acctttttga tagcgttctt
    22261 taaattcaag tgtttttcct tgtagatctc tatccgacaa tgacgccatt tggtctgcgt
    22321 aggattctac tttttttgca attttttcta attttcttag ttcgcctttg tcattttcga
    22381 taactttgcg tagaatattg gccattctct ttcctttcga tcatctaatc atttcatttt
    22441 aacataaata tgcaggcagt tcaagaaagg ttggtaaag
//
LOCUS       DAUGOH010000027        21112 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUGOH010000027 DAUGOH010000000
VERSION     DAUGOH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21112
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.027"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(172..471)
                     /locus_tag="VH957_001174"
     CDS             complement(172..471)
                     /locus_tag="VH957_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559089.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     VNFDDLRLTMVDMVSLSSEYDVIVTDMILEQTTDSEILFFNQMAPSVVANRLTDM"
     gene            complement(627..1094)
                     /gene="perR"
                     /locus_tag="VH957_001175"
     CDS             complement(627..1094)
                     /gene="perR"
                     /locus_tag="VH957_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEQ8559090.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICSDCQAKDQPDF"
     gene            complement(1146..1601)
                     /locus_tag="VH957_001176"
     CDS             complement(1146..1601)
                     /locus_tag="VH957_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEQ8559091.1"
                     /translation="MIYSFQNPSEDVLKAYLESAKTIAIVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEAQTILWSAGKEAIVMNRCLKIDYLQLVAKPECITNH"
     gene            complement(1779..4421)
                     /gene="polA"
                     /locus_tag="VH957_001177"
     CDS             complement(1779..4421)
                     /gene="polA"
                     /locus_tag="VH957_001177"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEQ8559092.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REDIIGFAWGHGEQIYASTDLGLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKVADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(4552..6279)
                     /locus_tag="VH957_001178"
     CDS             complement(4552..6279)
                     /locus_tag="VH957_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEQ8559093.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMAMTSGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAKKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(6295..7491)
                     /locus_tag="VH957_001179"
     CDS             complement(6295..7491)
                     /locus_tag="VH957_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8559094.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(7979..9070)
                     /gene="ulaG"
                     /locus_tag="VH957_001180"
     CDS             complement(7979..9070)
                     /gene="ulaG"
                     /locus_tag="VH957_001180"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEQ8559095.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(9323..10969)
                     /locus_tag="VH957_001181"
     CDS             complement(9323..10969)
                     /locus_tag="VH957_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEQ8559096.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INKALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(11294..11998)
                     /locus_tag="VH957_001182"
     CDS             complement(11294..11998)
                     /locus_tag="VH957_001182"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEQ8559097.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVAKMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(12000..12863)
                     /locus_tag="VH957_001183"
     CDS             complement(12000..12863)
                     /locus_tag="VH957_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEQ8559098.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPAIEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(12868..13530)
                     /locus_tag="VH957_001184"
     CDS             complement(12868..13530)
                     /locus_tag="VH957_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEQ8559099.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     MKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRI
                     WG"
     gene            complement(13621..14106)
                     /locus_tag="VH957_001185"
     CDS             complement(13621..14106)
                     /locus_tag="VH957_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8559100.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVRLAVQPLIDSKAVTSTYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            complement(14229..14507)
                     /locus_tag="VH957_001186"
     CDS             complement(14229..14507)
                     /locus_tag="VH957_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8559101.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(14578..16011)
                     /locus_tag="VH957_001187"
     CDS             complement(14578..16011)
                     /locus_tag="VH957_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8559102.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGIIQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYFFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(16318..18819)
                     /locus_tag="VH957_001188"
     CDS             complement(16318..18819)
                     /locus_tag="VH957_001188"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEQ8559103.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSGFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(19031..20170)
                     /locus_tag="VH957_001189"
     CDS             complement(19031..20170)
                     /locus_tag="VH957_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEQ8559104.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELAQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
BASE COUNT         6222 a         4665 c         4025 g         6200 t
ORIGIN      
        1 aatctctttt tcgatctttt tgttttttaa tttttcaagt tgaataatta aaccttgctt
       61 ttctttttca aggtaataga ctctactcct tgtaagtcta acttattctt aatcttattt
      121 atcgctcatt ttttaaattc cgatgctctc acagatatta tcattgttta gttacatgtc
      181 tgtcaatcta ttcgccacca cactaggggc catctgattg aaaaataaaa tttcggagtc
      241 cgttgtttgc tcaagaatca tatctgtcac aattacatca tactctgaag acagtgacac
      301 catatcaacc atggtcagcc tcaagtcatc aaagttgaca atctcaaaaa atcctccaaa
      361 atactctttt aagaagttgc caacattgtt ataacttctc tcaaccacta atagtttcaa
      421 gcgacgacgc gattgatttg taagaaagag attttcccag gtgaggaaca aacaatagag
      481 gagatgattg atggttcttt cctttaattc cttatgatcc ccagcaaata actctttaac
      541 ataagcaaca aaggtctggt agtgaactgg gggtttttga tttgtaaagg cattatattt
      601 ataatgcctt tatttaaggg ttaactctaa aaatcaggtt ggtcttttgc ttggcaatcc
      661 gaacaaatcc cgtaagcaat aactgggata cgcgtgacct tataacctgt ttgctcatgg
      721 gcttctttgg caatatccat aacatcaaca tccataaagt cagcaatctt cccacatatt
      781 tcacaaacca cattgacgtg ttgatggccc ataaagtcat agtaggtggt tagatcattg
      841 ctgattttca attctgagac aaaaccttca tcaactaaaa ctttcaaatt attatagact
      901 gtggcaaggc tcatgttagg aaagttaggc tgtaagtcac ggtaaatctt atcggcacta
      961 gggtgttctg tggactgaat catgtaagaa ataatggctt tacgtgtctc tgtaattcga
     1021 atatgttttt cccgtagatg ctctaggaca ttttcatagg catctagggc ttgctgatgt
     1081 gaatgaatgt ccataagctg ctactcctat ccttttttcc tttattatca cgcacgtctc
     1141 tagtttcaat gatttgtgat gcattctggt ttagcgacta attgcaaata gtctattttt
     1201 aggcagcggt tcatcacaat agcctctttg cctgccgacc ataaaatggt ttgtgcttct
     1261 tggttttcaa ggcctaattg cgcccaaaag actttggcct gacctgctaa aaagtctctg
     1321 gcaacttctg gtaaaaactc acttctgcga aagacatcta caatgtcaac ctcaaaggga
     1381 attgccttga tactggcata gaccttctct cccaaaataa gctgacctgc taatttggga
     1441 ttgactggaa tgatccgata atccatagcc tgcataaatt tggcgacacc ataagctgct
     1501 gtgtctttgc ggtcagaaag accaacaatc gcaatggttt tggctgactc caagtaagct
     1561 tttaggacat cctctgaggg attttgaaac gaataaatca cttgttcccc tatctattct
     1621 aaagctgttc aatataggag gataactcct aaagcatggc ttcaatcact tttaacctta
     1681 tccgtcaaaa agctcaaagc agcttcatga cttctcctac aattttttag tttattataa
     1741 cataagttgt caaaatgaga aataacaagt aagaaaactt atttggcttc gtaccagctc
     1801 tgcccagtac tttcatcgac acataaagga acagctaaat caacagcagc ttccatggtg
     1861 tctttgacaa gtttttttat agcagtcaac tcatcatttg gcacttccaa aacgatttca
     1921 tcatgcactt gaagcagcat tttagctcta aaaccacctg cttgcaaggc cttatccaga
     1981 ttaatcatag cgattttgag aatatcagct gcgcttcctt gaatgggcga gttgatggct
     2041 gtacgctccg caaaagagcg aacgttgaaa ttacgagagt tgatatccgg taattcacga
     2101 cgacgcttaa agagggtctc tacatagccc ttgtctttag cctcacgcac cacattttcc
     2161 atataggctt taatcccagg atagcgttca aaataggtat caatgtaaga cttggcctgt
     2221 ttacgggtga taccaaggtt atttgacaaa ccaaaatcag aaatcccata cacaattcca
     2281 aagttaacag ccttggcatt acggcggtca ttggcagtaa catctgctac cttgtcaatc
     2341 ccaaacacac gcatagccgt tgaggtatga atgtctgccc cttcattaaa ggcagcaatc
     2401 aaatgctcat cccctgaaat atgtgccagt acccgcaatt caatctgtga gtaatctgaa
     2461 ctcaacaaga cggcatcttc atgagatggg gtaaaggcct tacgaatcaa acgcccctgt
     2521 tccaaacgaa tgggaatgtt ttgaagatta gggtccacac tagacaaacg ccctgtctgg
     2581 gtgagatcct gcacatagcg ggtatgaatc ttgccatcag ccagaatata atcctgtaaa
     2641 ccaatcacat aggtggattg caatttagta atctggcggt aatccaaaat tttagccaca
     2701 attggagcaa tcggtgccaa acgttccaaa acatcaacag ctgtagaata acctgttttg
     2761 gtcttcttag tcatctcaag aggtagttgc atcttctcaa acaagatact gcccagctgt
     2821 ttaggcgaat taatgttaaa ttcttggcca gccatatcat aaatctcttg ggtgagcgct
     2881 tcaataatga ccttgttttg ctctgccata tcttgcaaag tcgccctatt aaccttgatc
     2941 ccttcaattt ccattttagc aaggacatta gccaaaggca attcaatatt ctgatagagg
     3001 tctagttgct catgggcagt gagcttgtct agcatttgag acttgctatc taataatact
     3061 ttgaccttac gagctaagtg ttctagtaag acgtctttat caggaacagc ccgtttagca
     3121 cctttaccat agaccgtatc gtcttcttcc aaagagatgt cagtaaaaat gcgggcaatg
     3181 gtgctaagct cattgtcttc tacagttgac agaaggtaat tagctaatct agcatcatag
     3241 ctaggtgcta ccaactcaat tcctaagtgg ctcaacaaga ccttgctacg tttaaaatca
     3301 taagtggcaa tgggtttttg gaagacctgc ttaaaactat ccgtcgctaa taggccaagg
     3361 tcagtggatg cgtaaatctg ctcaccatgt ccccaagcaa aaccaatgat gtcctcacga
     3421 tggtaattat cccgaagcgt ttcaaagtag aagatgtctt ctgcgctaaa caaatcagca
     3481 gacacattgg tcacttcttg ataggaaatg gcagctactg gctcttgagg catctggcta
     3541 gcaagacctt tcttgagttg cacaaaatcc atctcatcgt aaaattgaga gaggctagca
     3601 acatctggac cattgtagac aatatcatct aagccaattg tgataggaga tgctgtattg
     3661 atagtggcga gcgttttaga taggaaagct tggtcacggt cattgatcaa gttttctttc
     3721 atttttgagg ccttgaatcc atcaatatgc tcgtaaatgc cttccaaact accaaattca
     3781 tgaaggagct taaggcctgt tttttctcca atttttgtca ctccaggaat gttatccgat
     3841 ttatctccca tcaaggcttt gaggtcaata aactggtttg gcgtcaagcc cattttttcc
     3901 atgaggtaag ccggtgtgaa ttcttcaaat tcggcaaccc cttttttaga aatttcaacc
     3961 acggtatttt cgtcagttaa ctggatcaaa tctttatcac cactgacaat ggtcacatca
     4021 aaaggcactt ctgtgcgctc cgccatttta tcaagcgtcc cgataatatc gtctgcttcg
     4081 tagtgttcca actcataata agcaatccca agggctgtca acatctcacg aatataagga
     4141 aactgctcac gaaattcctc tggtgtcttg gcgcgacccg ccttataatc ggcatacatt
     4201 tctgttcgga aggtggtttt gcccgcatca aaagccacca gcacgtgagt aggctggact
     4261 cttttcatca tgtggtctag catcaaatga aagccataaa tggcattggt atgaagacca
     4321 ctatgatttt taaagcggtc aatttgattg tagagggcaa aaaaggcacg aaaggcaaca
     4381 gatgagccat caattaatag taatttattc ttgttttcca tagccttatt ataacacaga
     4441 gggacgggct tttctccttt aagccattgg ttttgctgat aagtaaatag ttaacctaaa
     4501 aagcctagga aaattcctag acttctctat ttgctattta gacaaaagca cttattttgt
     4561 ccaacttgat actttagatt tgttagcctc tacccatttt ttggcggcag cttctgggct
     4621 catgccttta ttgatgtcaa gcatgactgc ttccatatct ttttgggtcc agtggaactt
     4681 atcaatgatt ttgtagacat ttggaagatc ttttttcaag cctttacgag caatggtatt
     4741 gatgttctca gtcgagccaa aggtttcttt aggatcttta aggtacttca agtcatactt
     4801 ggcaaacatc cagtgtggtg accaagctgt cacgacaata ggatcttttt tcttgatcgc
     4861 ttgatccaag gaagtcgtca tggctcctgt tgatgccgcc actaactccc aactagatag
     4921 attatgatac tcttttagag tctttttggc tgctgccatg atacctgcac ctggttcgat
     4981 ccctgtgatt ttttgatcgg cttgtttgct taagtcctca atactattga catctgtcat
     5041 gtattttgga acagctaaac caagtttggt cccttttagg ttaggtccta aatcatctaa
     5101 ttttgacttg tatttctgat attgttggcc atgggtgact ggcaaccaag cactagttga
     5161 aaaatcagcg ttcccatttg caacggtttg ccacataacg gcattgtcaa gcggcgtcaa
     5221 ggtcacatgg taaccttcgt ttttcaaaac ttccgcaatc acatgagttg aggcaacctc
     5281 agaatcccac tgcacgtaag cgatgttaac agtttcaccc ttatctgcca taccagaagt
     5341 catagccata ataccgcgtc ctaaagcagc tatcaaaaag acagcaaggg ctgctagacc
     5401 aatccattta ttggttttgc cagctttggc tttttcttga ggtttgctat tgaacaactg
     5461 tgtcatacgg tcaagcacaa tcgccaagat aaccaaggca agaccactga caaatccact
     5521 accaatatca gcgtgttgaa gggctgacaa gacttcacgt cctaaaccag gagcaccaat
     5581 catggagcct gttactacca tggaaagggc taacatcatg gtctgattaa cacccgccat
     5641 gatggtattt ttagctaaag gcaattctac cttgaagagc ttttgtttcc cagttgaccc
     5701 aaaggcatct gaggcttcaa tcaattctgt tggaatgtca cgaatggcca aatttgtaaa
     5761 acgaactgtt gggggcaagg caaagatgac tgaagcaaat actccaggca ccataccaat
     5821 accaaaaaag gcaacggcag gaatcaagta aacaaaagcc ggcatggttt gcataaagtc
     5881 caaaatagga ttcacaatct gacggacagt ggcattttta gccatccaaa tccccagcgg
     5941 aataccaata agtaccgaaa tcaaactagc tactaacacc agagtaaagg tattcattag
     6001 ctgcttccat aacccttgat tgtaaataaa gagcaatcct aacaaggtaa aggttggcaa
     6061 aggccatttt ttcttagcaa ggaaaaacat ccctgctgtt actagaacaa taaaaagtaa
     6121 cgggtggata aataaaagtg ttttggtcat ccaatccatc aaaaagctac caactacttg
     6181 cataatatca aatagacctg agaaagtttt agttagccac tccgttagct gctccaccag
     6241 ttgagctact ggtaattttg tttgtaatat cgtttccaaa atgcatcact ccttttagtt
     6301 aaggtcttcg tctgagatat tagccaaggc ttcaatcact cgtcctcgaa taatgacacc
     6361 taacagacga ttgttatcat ctgtcactgc aatcggagca gatgaatcat agataagagg
     6421 caaaatatct gtaataatag tatcttttga gacagttctc acatcgcgat caatcacttc
     6481 tgatagcggt aacccttttt tgcgcgcctc tatagcggca tcggccgtca aactaccgac
     6541 taattggcgg cggcgattcg tcgccatcaa catagacacc tcttcgttgt gcatacggtt
     6601 caaggcaact tgaggtccat ctaattcaac agtagttgtt aacggtttga tcatgatatt
     6661 ttgtgctgtc aagactttag aacggtccac atcctcaacg aattcacgca caaagtcatt
     6721 ggctgggtta gtcaagattt cctcaccagt accaatttgc ataatttgtc cgtctttcat
     6781 caaagcaatc cgatcaccaa tccgcaaggc ttcattcaag tcgtgactga taaagatgat
     6841 ggtttgtttc atgctatctt gcaaatcaag taattcatct tgcatctcac gacgaatcaa
     6901 aggatcaagc gctgagaatg cctcgtccat taagagaatt ttagggctat tagctagcgc
     6961 acgggctagg ccgacacgct gctgcatccc accagatagt tggtttgggt actggtcttt
     7021 aaaatctaat aggcctgaat tatcaagggc tttttctgcc aatcgctggc gttcttcttt
     7081 gggaacacca cgtaattcca aaccaaattc ggtattttcc aaaatggttt tatgaggaaa
     7141 gagggcaaag ctttgaaaaa ccatgttaat gtcatggcgg cgcacctcac gcagctgatc
     7201 tgctgacatg gttgagatgt ctttaccttc cagcaagata gatcctgctg aaggttcaat
     7261 caaacgattt agcatgcgga caagggttga tttcccactt cctgatagcc ccataataac
     7321 aaagatttca ccttttttga cctcaaaact agcgtcatag acacctacag tagcgcctgt
     7381 tttcttaaaa atctcactct tatttttgcc agtctttacc atctcaagag ctgctttttg
     7441 ttttttgcca aaaattttac tgagatgttt gacttctaaa attgtttcca ttcgtttttt
     7501 ctcctaggta atcgtttatc atgtgaaata gtgacatagc tttggcgaaa tattagctaa
     7561 tatttaacaa agtagctcta cacaattaat aaacgtgtgg tcactttttt acttaaaaaa
     7621 agaatctgcc gaaacagaac ataactatat tatcacgtgt ggtcactttt tgtcaaggac
     7681 aataactcga tctggtaatg ccacaatgat aggtgatcgc tttcattctt ttagatatgg
     7741 tcttttaacc agtacaattt tttatcacaa ctgatgacta tttctttgat gattaggcta
     7801 ttgttacatt agaaatcctt cttttaccta taatatctat tttgcggcca tcgtaaataa
     7861 cgaccacggt gactcttaaa catttgctca tctctccaaa aaaactcacc taagacagtg
     7921 tcctatgaag cgagttagct taatcaggca ctatcatctt aggtgagtag ggtgttgctt
     7981 atagtaaagc tttaaattgg atattagaat cttctaagaa gcagtcatca aatccacgag
     8041 gatgatggta ttcgatacga ttttggtctt gtggataggt gtacttgcca ccaacctccc
     8101 agataaaggg atggaaatcg tattggagac gttctttgcg cattttccac agttcaagga
     8161 tttcatctgt tgatgccata aagtttgacc aaatgtcata atgaactggg ataacgactt
     8221 tagcacggag attttctgcc atacgaagta ggtcaacaga agtcatcttg tcttgaatcc
     8281 caattgggtt ttccccatag ttatttaaca caacgtcaat atcataatca cgtccatgtt
     8341 tagcaaagta gttcgaaaaa tgagaatccg caccgtgata gatggtacca cctggtgttt
     8401 caaaaatata gttaacagct ttgcgagcca tgtcatcatc tgtgatagct aaacctgcta
     8461 aatcaccatc ttgagcatca gctccttgta ttgggagagt taccagacag gtgcggtcaa
     8521 acgactctac agcggtgatc ttaatatctt tgaattcaaa gctatcacct ggctttaaga
     8581 tcataatacg atcttttggc acaccccaat ttttccaaac ttcaccacat tcataaggtc
     8641 ctacaaattt aacatgatta agttttgggt tattgataat ggctgccgca gtattgatat
     8701 cgatgtggtc actatgataa tgagaaacca aataataatc caactcatta atcataaatg
     8761 gatcaatcac cattggttgg gccctaagat tgggctgtaa tttacgagct cctgccatat
     8821 tagccatttg atgtccacga accatatcct taacttgctt ggtcgctttc ccacgatttg
     8881 accataagtc catgacaaca ttagcaccgc ctggtgtctt aatccagata ccacagtttc
     8941 ctaaccacca catcgcaaag ttgtcagctg gcacgacttc ttgctcgatt tcttcattta
     9001 accatgttcc ccattctgga aacgtgttaa ggatccatga ttcacgtgta atatcttgta
     9061 ctttagtcat tagggtttcc tccgaatttg ttcttcgttt ctatacttta agtatagact
     9121 ttcttgtcaa tgataaaaag accaagtgtc acacagatct gtgttcaaaa gtggactgac
     9181 tttttcatta gctcagtcta atactatctc attttgcaca ctgtatctcg catcaatact
     9241 gtattcaaag ctatattaaa aacctcagtt atatttttct atgtcataga aaactgaggt
     9301 actttgacga cttaacactt actcatagca gctcgcgatg aatgagtttt tcaattttag
     9361 aaaccaaggc ataacgatct gattcatctt ttacaacagc ttcaatagct tttgtgagct
     9421 ctgtagaaaa gcgggagtgc tcactcaagc gtccttgctt tgaaaagcgt atcaatttga
     9481 tgatatcatc gtcacttaaa atagggttaa caataagcat cgggatttta gtctttagcg
     9541 tatctgtagt agcaacaatc atatcgactg ctaaaaggtc gtaaacactc tgatactgtt
     9601 ctgtcgtaaa aacagcttca atctgaccat ttgctagata cctttgacac tgtttgaaca
     9661 ataacttttg aatgcctatc ccatcatctg aaacaataac gagtttggtc ttttcttgct
     9721 ctgtattatt gtgacgcagc tctcccccta gatggatagt caagtaggca atatcatcgt
     9781 ctgtcaagct aatcgtccaa tcttgttcca aaatagtggc acaagattga gtcatagcaa
     9841 acaattcttc gtatttttct ttaatatggt ctgttaaggg attaactaaa aaaatcccat
     9901 aagctttacg gtaaacgagc gccttacagt gggtcgtcaa ctgcttcagc aaatcctgtt
     9961 tatgcgtgaa atgtaactga taacggctct ccaactggtc aataaagtga ctaatggttg
    10021 ctcgcatgtc atcataatct tgactttcca cgtgatgatc ttgatctttt cgaaaagaca
    10081 acatcaacat cgctaccata ctaacttcga tatcatccaa atgaagctta aaattatggt
    10141 aaagctctct agctaagtcc tgagcaatgt gatattcttt acgtttccaa atcaaatgaa
    10201 attcttgttt aagagcagac tttgtttctg aatcaagacg catattacga taacttaaaa
    10261 gcatgaaagg taaaatctgc aacatgaatt ggctatcttg ggtattaatt gtctttccta
    10321 agctagcttg agataaaaag agatactcat gaaaataagt caaaatatct ttagaaaaat
    10381 agaccgataa gccttgtatc tctgagagtt tacggttgaa tatatcaata aagctagtat
    10441 tgccaccttg gtaaacgtcc actaacaatt tgtacaggta ttgaataaga gccattggat
    10501 gacaaccaaa ataatatccc ctagcctttg tcgcatgaag ctgaatcttg tattgtttgt
    10561 cttccagttc ttcccttaac tcagtcaggt catttaaaat cgtgttacga gacacatcat
    10621 tgatctgcat cagtttatca atggtcacgc gctcagtgga aaccgcaata taaatcgagg
    10681 atagtcgtct gcgctcatca cttttcatga cataattata atcagtcact tcttctaata
    10741 ataagcgaca agcagctttt tgatccgccg ttaaaagaat gccaagtcta ggataagaga
    10801 taatctgatc tactcccttt ggcaaagcct tattaatttt gtcaagctgg taataaactt
    10861 tacgacgtga ctgatttaaa gcatgagaaa tggccataac tgtctcaggt gtttctagtt
    10921 taagtaaata agacagcaag tcataactct ttttatctaa aatcatcatg tttacaaacc
    10981 tcctctctga aaatccatcc ttgcttattt tatcatgatt tcagtgactg cgcagccaag
    11041 ttttgaaaaa ctcaccataa taagattcgc ttaatatgat tcgagctaat cacctcaact
    11101 gatccaacac caacacctta tatctggtct ctaagaactc cacaacatac gattcatcca
    11161 gtttgtgctc attggcgttt aaacagttca tcgaaaagga caagtcaaaa ggacttgccc
    11221 aaacaatgat taacaaaacc ttgaactttt tggcttctag tgagaacctg tgctaataag
    11281 ccatatcgcg acctcatttt tgaccgtaat aagcatttgg gccatgttta cgcaaataat
    11341 gcttatccat aatgtatctt ggcgctggct ctacgcgtgg attgatttgt tctgtcaagc
    11401 gattcatctt agccacttct tctaagacaa ccgagtggta aacggcttgc tctggggttt
    11461 tcccccacgt aaatgggcca tgattacgca ccacgattcc tggaaccgcc atcgggtcaa
    11521 gacctcgctt gctaaactct tctaaaatca cgttgccagt ttcttgctcg taagccccat
    11581 caacttctgc ttttgtgaga gaacgagcac acggaactgg tccatagaag tagtcagcat
    11641 gcgtagtccc ataaaacgga atatcacgac ctgcctgagc ccaaccgaca gcttctgtgg
    11701 agtgagtgtg gacaataccg cccacttctg gccaagcttt ataaagttcc acatgggttg
    11761 gcagatctga agaagggttc aaatcacctt cgaccacatt cccatcaagg tctgtaacaa
    11821 ccatattttc tggtgtcaag aggtcgtagt ccaccccaga aggcttgatg acaatacgtc
    11881 ctaattcacg acaaacttca gagacattgc cccacgtaaa tttgacaaga ccgtgttgtg
    11941 gtagagactt gttagccgca cagacacgtt cacgcatttc ttgcaagttt ttcgccatat
    12001 tatgccaacc ccgctttctc aataagtggg taaaggaagt cctgagcttc tttgatagca
    12061 gcttttgttt cctccaccgt gtcacaattt tctgaccaca tttcaatcaa aaaaggccca
    12121 ttgtagttgg ttttcttgag gaccgcaaac agctcttgcc agtccacaca accttgacca
    12181 aatggcacat cacgaaactg cccttttgag gtttccgtga cagcataagt atctttcaag
    12241 tggagggctg caatggattt gtgcccattg taaaattcac tccacaaatc attatgccaa
    12301 gcagaaacat tgcctgcatc aggataaaca aagagataag gcgagtcaat ctctttttca
    12361 actgccaagt atttttcaat agagttgata aaagggtcat ccataatctc aatagaaagc
    12421 atcacttggg cttcttcggc ccagtcacaa gattgtctca agtttttgat aaaacgagca
    12481 cgggtttcag gcgatttttc ttcatagtaa acgtcataac cagctaattg aatggtacga
    12541 acgcctaagt cctgtgccaa ttcaatacat tgtttcatca gtttaaggga cttggcttca
    12601 atagcaggat catttgagcc tagtgggtaa cgtctatggc cagaaaaaca aatggtcggg
    12661 atgcgaatgc ctgtttcata aatggctttc actaaatcaa gccgttcttc cttagtccac
    12721 tctaagcgcg ctaagcgagc atctgattca tcaacagaca tttccacaaa atcaaaacct
    12781 aagtcttttg caaattgcaa gcgttcacgc caggtaaact gttttggcgt tgctttttca
    12841 taaataccaa taggacgcgc cataaagtta cccccagata cgtctgattt catctttgaa
    12901 ggcacgcgcc gctgcagcag gatcttctgc ttcagtaatg cctcgccctg cgataaaggt
    12961 aaagacatca accccttcaa aaagtttcaa agtgtctaca tcaagcccac cagttactga
    13021 cacgcggaag cccatgtcaa tcaatgtttt caccttgtta aggtcttttt caccccaagt
    13081 ttctccagca agaagggcat cacgagattg gtggtaaatc gcttgggaaa tcccagcgtc
    13141 aagccataat tgagcttgct cataagtcca atcaccataa agttcgattt gaatttcccc
    13201 acggtcaccg cgctcttctt tcatagcctt gagggctgct tccatggttg gaatcgtcgc
    13261 acagcaaatg caggtcatcc agtcagcacc acgttttgca ttgtttttag cgaccgtacc
    13321 gccagcgtca gcacatttgg tatctgctac gataattttc tctgggaaga ggctgcgtaa
    13381 tacctcaact agttcgcttc ccacttgaag caaacaaacg gtaccagctt caatcacatc
    13441 tacttcgtga cccacagcaa cggctgcttt aacagccccc tgtaagtcag aatggtctaa
    13501 agcaacttgt aaatttggaa tatgtgtcat ctctttttcc taaaactctt agccaccgtg
    13561 caaactggtt aagagttctt atcctttcca tcattcgtta gtatcctgtg taaggaaagc
    13621 ttaagcattc aagtccatac cttctaagta aggactatct ttagattctt ctaccatttc
    13681 taggacctct ttaggacttt ggcaggccac caagcgttca atggcgttat ctagttcaaa
    13741 caaggccaca atttgtggga tagccactgt tgtgtgaata gaagggtctg tagcggccaa
    13801 cgtcaaaaga acagaaacct ctttaccatc tgagaaggta actggttttg ttagtgtaat
    13861 caaagcaaat gcattgcgat taacgcctaa acctgcttct gcatggggca tagccatacc
    13921 tggcatcaac acataataag ggccgtattt ttctgttgat gcaatgatgg cgtcgtagta
    13981 agttgacgtc actgctttgc tatcaatcaa aggttgaaca gctaatcgaa cagcctcttg
    14041 ccaagtatca gcacttagcc ccaatcggat ggagttgttg tcaataaagg cttgttttaa
    14101 attcataaaa actatctctt tctagtgtct tgctttgcaa cacacaccat ttttactagt
    14161 tttatcctac taaagagaaa gagctgaaaa ccttcgtcac aactccttcg ttttgattca
    14221 gaattagctt atagcacttc ttgtagtttg gttttaattt cattatcatc catcaggtta
    14281 tcaagaccaa ccaagtggcc tttggtacga ccatcaagct catgaatcaa gtggtttgat
    14341 gccactacaa tatcataacc agaagctaga cctttagctt caccaactga gcaagaagct
    14401 gactgaatat ctgtcacgcc aagttgacga agcgcatttt caactttcat tttgatcacc
    14461 atagatgacc ccataccatt gccacatgct gttaagactt taaccattgt tttttcctcc
    14521 gaaaatgttt tattattatt ttgttaaaat agcagagcta tttcttaaga tgcagtgtta
    14581 ttgagcttcc ccacggtagt aagcttcttt gtccttagct tttgcgaact gcaattgtgg
    14641 aatggcaagt aagaagatgc aaacaagcac ataccctgca ataccaagga atttgaagaa
    14701 gtacccaaat ggtaaccatg gaagaaccaa gtcgatatta ccgtgataac cacctgtaag
    14761 tcctaaaaga cctacagcaa cagcaccaag tgccacctga ataatacctg agataaatga
    14821 tagagctacc gctgctttcc agccaccacg tttatctgca taaaccgcaa ttgccgcatt
    14881 atcaaagaat acgggaacga atcctgtgat aattaagatt ggatttttaa agataacaag
    14941 aagagcaatg gtgattaatt gaccaatcaa accaaaggca aatcctgaaa gcaccgcatt
    15001 tgaagaacca aagccatagg aagctgcaac gtcaaccgct gggaatgacc ctggaagcaa
    15061 tttacttgag atcccttgaa aggcattggt caattcagaa acaaacatac gaacaccctg
    15121 catcaagata aagagataaa ctgagaaggt gagagaggtt tgcaaaatat acatgaagaa
    15181 agcttgctta gctgggttga atgctccagg tccgattaag tccacatcag acataatgtc
    15241 tggaccaagg acagccaaga tagctccgaa aaagaccaac atcaaagttg ctgacgcaac
    15301 aacagtatca tggaaaatgt ttaagaaggt tggtaatttt aggttatcaa ggttttcttc
    15361 ttttttacca aagaacggtg caaccttatc cacaaaccaa atcgcaaatt gttgttggtg
    15421 accaatcgca aacccaccgc cacctgtaag gcgttgagtt gcttcaacgg tcatgtttga
    15481 gctgatagcc cagtaaagac cacagatgat accaactgcc catgccccaa aagcattttg
    15541 gaattgaggg attaaaagaa ggacaaagac cgaaatcgtc gctgcctgtt ggaccatgat
    15601 gtgacctgtg atgaaaaggg tacgaacttt agtgaccttg cgaagtgcaa ccaaaagaat
    15661 gttgacccca aatccaatca agagagctgt cgtagcaaca ctgatgaagc ccatctcttc
    15721 taacttagta ttagcagcag ccaaaccaaa ataaggatca ataacggcgg ctttcaattc
    15781 aaatttcttg gcaagagcaa ccaagatcgg acgaaaagtc gttacaagac cgcctgctcc
    15841 aacgttcaaa atcaagtaac caacggtagc ctttacaaaa ccagcaaaga cctcataaat
    15901 gggtttttta aggagtaaat acccgattaa aaccaaaaga cctacaaaga acgctgggtt
    15961 ttgcaaaata ttttgcgaga accagtttag gggagctagg agcatttcca taagaactac
    16021 ctcttttcaa agttaataaa gataaagtgt ttatatgttc attataggta atgaaagcgt
    16081 tttaaaaaag accaactatc acacaaagaa gtgttcaata ttagacttaa gttaacttat
    16141 tttaaaattt aactacactt agtaaaaagg agaaaatcac cctaaacaac gattaaaaac
    16201 cacaagaacc ttcgttcttg tggtttttct agatgagttg ctttttgaat agatcagctc
    16261 tttggcatta actgtgacgt gacgcaaata accactgaag ggctgtgtca cctcaaacta
    16321 tttgataaca atattaacga gtttgtttgg tactgcgatg actttgatga tgtctttgcc
    16381 tgcgatttcg gcttggactt tttcgttagc aagagcaact tcttgcaatt cttcgcgtga
    16441 aaggtcttta gcaactacaa gtttagcttt gaccttacct ttgatttgga caacgatttc
    16501 cacatcgttt tcaaccaatt tgctttcatc ataacttggc catggcacgt aagagattga
    16561 ctcacctgag gctgtcaagg cttgccagag ttcctcaccc aagtgtggcg caaatggtgc
    16621 aatcaattgc acaaagcctt tggcatagtc gctaaagagt ttgtcttcct tgttagctgc
    16681 attgacaaag accatgagtt gagcgatagc tgtgttgaat ttcatttggt caacttgctc
    16741 agtaacggcc ttaacggttt cgttgtaaac cttgtcaagg gctccgctat tttcctcagt
    16801 gatctcttta gttgtgatca aacggtaaac acggtccaag aacttacgtg agccttcaag
    16861 accttcttca gaccaagcga tggaagcgtc aagtggtccc atgaacatct cgtaaacacg
    16921 aagagtgtca gcaccgtact gctcaacaac atcatctggg ttgacaacgt tcttaagtga
    16981 tttagacatc ttagctggtg cttgttcaag ctcttcccca gtttccacat ggaagaagct
    17041 accatcacgt ttttcaacct tgtcagttgc cacaagagca ccacggctat cgcggtagct
    17101 tgtccccaaa atcatccctt ggttaaagag tttttggaat ggctctttgg taggtacaac
    17161 accgagatcg taaagaacct tgtgccagaa gcgagcgtag agaaggtgaa gcacggcatg
    17221 ctctgcacca ccgacataga tatcaactgg caaccattgt ttgaggagtt cctcatcagc
    17281 cagtttttcg gtgttgtgtg gatcgatgta acgaagataa taccagcttg aacctgccca
    17341 ttgtggcata gtgttagtct cacgacgacc tttcacacca tcttcacgag tcacttccaa
    17401 ccagtctgtc acgttagcaa gtgggctctc accagtacct gaaggacgga tatccttcgt
    17461 tactggaaga accagtggca actcactctc aggaaccgct gttgaggtcc catcttccca
    17521 gtggatgatt gggattggct caccccaata acgttgacgg ctaaagagcc agtcacgaag
    17581 acggtaagtg actttctcat taccgacgcc ttctgcttca agccattcga ccattttggc
    17641 aatagctgac gctttgtcaa gaccatctag gaagcctgag ttgatgtgaa gaccgtcttc
    17701 tgtaaaggca gcctcttcaa cattaccacc ttcaagaaca gggatgatgt ctaggttaaa
    17761 ttgttttgcg aattcccagt cacgttcatc gtgggctgga acagccatga tagcaccagt
    17821 accgtagcta gcaaggacat agtccgcaat ccaaactggc atttctttgc cgttgaccgg
    17881 gttaatagcg tagctacctg tccagacacc agttttttct ttggcaaggt ctgtacgagc
    17941 aaggtctgat ttgagacttg cttgacgttt gtagtcagcc acggcttctg cctggtcagc
    18001 tgttgtaata gcatcaacca aggcatgctc aggagcaaga accgcgtaag ttgcaccaaa
    18061 aagggtgtca ggacgtgttg taaagacagt gaagtcctta tctgtatcct taaccttgaa
    18121 ggttacatta gcaccagttg atttaccaat ccagttgcgt tgcatgtcct tgattgattc
    18181 tggccagtca acttcttcca agtcttctag caagcgctct gcataggcag tgattttgag
    18241 catccattgg cgcatgggtt ttctgacaac tgggtagccg ccacgttctg atgtcccatc
    18301 tggaagaacc tcttcgttgg cgatagctgt tcccaattct tcaacccagt taacgggaac
    18361 ttcagcttcg taggctaggc ctttttcata aagcttggta aagatccact gcgtccactt
    18421 gtagtagtta gggtcagttg tgttaacttc acgatcccag tcgtatgaga aaccaagagc
    18481 attaatctgg cgtttgaagt tagcgatgtt ttcagctgta aactcggctg ggtcattacc
    18541 agtatccata gcgtactgct cagcaggaag tccaaaggca tcccaaccca ttgggtggag
    18601 gacattgtga ccttgggcac gtttgaaacg gctgagaata tcagttgctg tatagccttc
    18661 tgggtgacca acgtggagac cagctcctga tgggtatggg aacatatcta gggcataaaa
    18721 cttaggtttt gatgcgtctg ttcctgtttt aaaggtgtga ttatctgccc aaaaggcctg
    18781 ccatttgggt tcaatagcgg tgtgatcgta aaatgtcatg tgaaatctcc catgtaaaaa
    18841 atctagtctt cttattatag catgagatga agcttttagg aatggtcaag acatgactag
    18901 caccttggct tttgagactt cagacgatta gctattttta aaacctgctt tagcatcaac
    18961 catcctcaca aaaagctaat aaaaaaagcc agacttgctc tgtaaacaga gccaatctgg
    19021 acaaatagac ttaaaaagca agtgcttgct caaaatcggc caataagtct tcgatatttt
    19081 caacaccaca agacaagcgc agcaaaccat caacaacccc ttgttccaac cgcgcttgtg
    19141 atgataaaca agcatgagac atcgttgctg gatgtgacaa aatggactct actccaccta
    19201 gactaacagc taaaatcggc aactgaatac gatgggtaaa ggtcatcagc tcctccttag
    19261 aagccaactc aaaggataaa acagcaccac cattcttagc ttgttgcagg tgggtatcgt
    19321 gattaggatg actgtctaag ccagggtaat gtaccttaag aactttgggg tgcttcgcta
    19381 aatagttagc aagctgctga gcatttttta ccgcttgttc catacggatc cccatagttt
    19441 tcatgccacg aagaatcagc caagcgtctt cgaccccaac aattgctcca aagttttttt
    19501 gaaaaagctt gagctggttg tagatagcct cattattggt agcagctaaa ccagctacca
    19561 catcactatg accattgata aattttgtca cactttctac cacaatatcc acacccatag
    19621 ctaagggttc ttgatacaaa ctggtcataa aggtattatc agccacagtt agcacaccat
    19681 aagctttggc gagttgcgca agctctgaaa tatcacaaat tttcaagagc ggatttgacg
    19741 gtgtctctag ataaatcata cgcgtattag gcctgatact tgcttttact gttgctaaat
    19801 cagccatatc tacaaagctt gtttcaatct gataattggg taaaatagct gtcgcaaatt
    19861 gacaagtccc tccatagacc tccaatggga aaatcacatg atctccagct tttaagagca
    19921 tcaaaacagt tgaaatagca gccataccag atgcataagc caccgcataa gtcgcttttt
    19981 ctaaacaggc taacccgtct tctaaagctt cagtcgttgg gtttgaaaag cgtgtgtaca
    20041 aatgtttttg actaggacaa tacagttctg aattgtggaa cgtcgaagtc tgatagatgg
    20101 gaactgaagc tgctcctgta aactcgtcaa taaccgtata gccatgtaat aaggtcgtat
    20161 tttctctcat ttcgtgcacc tccgcaatag cgttaactcc aatgaactct cttttagaca
    20221 atggtcccac cccaatggtt gcacaagcca aaaagctctt caaaaaagcg tgatctgcta
    20281 acctataaga aaagtagtgg acacctttta aatggataat gaatttttcc aacaatatca
    20341 tttttagatc gattacgttt attatacaac ctttagctaa gtttgcaagc ccttttatca
    20401 tctttgacca agctgccaac acctctccag caagttaaag tatagctacc tttggcccca
    20461 tcgtctcaaa agctcaaatt atcacactga cagtcctacc ttgcatcgtc acctactcaa
    20521 tatggcaata ctgccatcaa aatttcatta aaagttcata atttatttca tttaatgaaa
    20581 aacagaactt gttttcacca tgcgtcttat agtacactgc taaagtacta tttattttta
    20641 ggagagaaat atagtgaaaa acaaattatt tttagttgcc cttgcgaccg taactgtcct
    20701 agggccctct ttagcaaccc ctcatcatca gaccgtgcat gcggctgagc aggcaaaaga
    20761 accccaaacc agctcaatga cgtgtactaa cgatggatct gtatgcgctg gctggcatag
    20821 tttatcagaa ggagacagta taacttcaaa ttcatcttca aacaccaaga cttccctgtt
    20881 aaactggtta tggagcttaa taacaaattt gtggaattct gcaaaaaact tgttcatcta
    20941 agatctctat aatcatatcc atggaattta aataaccatc tcgtggcggt tttctaatcc
    21001 taggtcgcca cacttcttat tcagataaat aataataaaa acattaaaat aacacttgat
    21061 ttattaacaa aaagttagta taatataatc acaatacaaa ttaaaggagt ta
//
LOCUS       DAUGOH010000028        20643 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUGOH010000028 DAUGOH010000000
VERSION     DAUGOH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20643
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.028"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..384
                     /locus_tag="VH957_001190"
     CDS             <1..384
                     /locus_tag="VH957_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8559105.1"
                     /translation="GKDGKDGQNGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTAPHT
                     PKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNP
                     FFTAAAVAIMTTAGVVAVAKRQENN"
     gene            584..1021
                     /gene="msrB"
                     /locus_tag="VH957_001191"
     CDS             584..1021
                     /gene="msrB"
                     /locus_tag="VH957_001191"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8559106.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            1151..2170
                     /locus_tag="VH957_001192"
     CDS             1151..2170
                     /locus_tag="VH957_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEQ8559107.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLNGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKMGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            2377..2802
                     /locus_tag="VH957_001193"
     CDS             2377..2802
                     /locus_tag="VH957_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8559108.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            2821..3312
                     /locus_tag="VH957_001194"
     CDS             2821..3312
                     /locus_tag="VH957_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8559109.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            3329..4138
                     /locus_tag="VH957_001195"
     CDS             3329..4138
                     /locus_tag="VH957_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8559110.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            4135..4962
                     /locus_tag="VH957_001196"
     CDS             4135..4962
                     /locus_tag="VH957_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8559111.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            5098..6747
                     /locus_tag="VH957_001197"
     CDS             5098..6747
                     /locus_tag="VH957_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8559112.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            6751..7539
                     /locus_tag="VH957_001198"
     CDS             6751..7539
                     /locus_tag="VH957_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8559113.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            7533..8579
                     /locus_tag="VH957_001199"
     CDS             7533..8579
                     /locus_tag="VH957_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8559114.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNIAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            8694..10091
                     /locus_tag="VH957_001200"
     CDS             8694..10091
                     /locus_tag="VH957_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEQ8559115.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVNLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            10193..11989
                     /gene="uvrC"
                     /locus_tag="VH957_001201"
     CDS             10193..11989
                     /gene="uvrC"
                     /locus_tag="VH957_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEQ8559116.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            12174..12776
                     /locus_tag="VH957_001202"
     CDS             12174..12776
                     /locus_tag="VH957_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEQ8559117.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            12901..14310
                     /gene="pepV"
                     /locus_tag="VH957_001203"
     CDS             12901..14310
                     /gene="pepV"
                     /locus_tag="VH957_001203"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEQ8559118.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDQLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLNVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGTLSMNA
                     GVFTFDNQSADNTIALNFRYPKGTDAATLKAGLEKLPGLTKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(14378..15754)
                     /gene="mnmE"
                     /locus_tag="VH957_001204"
     CDS             complement(14378..15754)
                     /gene="mnmE"
                     /locus_tag="VH957_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEQ8559119.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPADLIPISVLTNHNIDLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     misc_feature    15925..16060
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            16090..16590
                     /locus_tag="VH957_001205"
     CDS             16090..16590
                     /locus_tag="VH957_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEQ8559120.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            16655..17020
                     /gene="rplL"
                     /locus_tag="VH957_001206"
     CDS             16655..17020
                     /gene="rplL"
                     /locus_tag="VH957_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEQ8559121.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            17319..17918
                     /locus_tag="VH957_001207"
                     /pseudo
     CDS             17319..17918
                     /locus_tag="VH957_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            18098..18423
                     /locus_tag="VH957_001208"
                     /pseudo
     CDS             18098..18423
                     /locus_tag="VH957_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            18414..18691
                     /locus_tag="VH957_001209"
                     /pseudo
     CDS             18414..18691
                     /locus_tag="VH957_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            18737..18946
                     /locus_tag="VH957_001210"
     CDS             18737..18946
                     /locus_tag="VH957_001210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559122.1"
                     /translation="MTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLLN
                     RANSLEELLLKAKEVNLTIDLKQKM"
     gene            19212..19907
                     /locus_tag="VH957_001211"
     CDS             19212..19907
                     /locus_tag="VH957_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
                     /protein_id="HEQ8559123.1"
                     /translation="MEHQIERLIAEDIYIKVSFGVKQSGLIFIPNYQLDIRKEENHKK
                     YKVYIRETAQFFIYNKEASELNRYMRGHELICQLTNDSKSIPKRRRQTIDTLKKKIEE
                     ISLLIELDTENKPYQDIKDDIVKDMAQLDLTITELQDHIAHLNKVAEVLLNLNNNDIE
                     NRRLARYDYAKMNLTAAIKIEEVEKEIETSQNELNISIDEYEYLVRRLEKFGEILSDS
                     KIIDTSRNEIQWE"
     gene            20058..>20643
                     /locus_tag="VH957_001212"
     CDS             20058..>20643
                     /locus_tag="VH957_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8559124.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFH"
BASE COUNT         6534 a         3621 c         4277 g         6211 t
ORIGIN      
        1 ggtaaagacg gcaaggacgg ccaaaatggt aaagatggtc ttccaggtaa agacggtaag
       61 gacggtcaac caggtaaacc ggctcctaaa acaccagagg tccctcaaaa accagatacc
      121 gcaccacata ctccaaaaac ccctcagatc cctggccaat caaaagacgt gacacctgct
      181 cctcaaaacc cttctaatag aggtctaaac aaaccacaaa cacaaggtgg taatcagctc
      241 gcaaaaacac cagcagctca cgacacacac agacaattgc cagcaacagg cgaaacaacc
      301 aatccattct ttacagcagc tgctgtagct atcatgacaa cggctggagt tgtagctgtt
      361 gcaaaacgtc aagaaaacaa ctaatcctct ttttggctac ctaactgatg gaaagtaaaa
      421 ctcagagaga acctcaaggt tctctctttt ttgaatcaag tttttgaatc aagatagtag
      481 ctctaggtat aacgtcttgt ctgaggtgct gtgaacaaat cagttaccac tcacctcttt
      541 ttttggtaaa atgtaagcac taaaacatca aaaggagttt tccatggaaa catcagatga
      601 gttaaaacaa cgcattggtg atctttctta cgaggtcacc cagcatgcag caacagaatc
      661 tccctttaca ggagaatatg ataatttttt tgagaagggt atttatgtcg atatcgtcag
      721 tggtgaggtc ttgttttcat cactggataa atttaattct ggctgtggtt ggcctgcctt
      781 ttcaaaaccc attgaaaatc gtatggtcac aaaccacgat gactcttctt atgggatgag
      841 acgagttgag gttaaaagcc gtgaagcagg atcgcatttg gggcatgtct ttagtgacgg
      901 ccccaaagaa gctggaggct tgcgttactg tatcaattca gcagctctta aattcattcc
      961 ttatgaccag atggaaaaag aaggctatgc ccaatggctc acattgtttg atgagacata
     1021 acagggtttc aaaatgacta aaaaagaagc gtcagtgatt cccacaagca ctggattggt
     1081 gaggcgtacg ggtcaatttt acaagccttt gtaaaaggtc tataataggg aatgaaaaaa
     1141 ggaggttagt atgtcaactc acttaagaaa acttccaggg ctgttacttt gcttattgtt
     1201 agctcttcca gcctggtgtt tagggcgctt gtttcctatt attggagcac ctgtttttgc
     1261 tattctttta ggaatgttgt tagccttgtt ttatgaacat cgtgacaaga ctaaagaggg
     1321 aattagtttt acatccaagt atattttaca aacagcagtg gttttgcttg gttttggatt
     1381 aaacctaacc caagttatgg cagtaggcat gcagtcttta ccgattatca tttcaactat
     1441 tgcgacagct cttttggtag cttatggctc acagaaatgg ctgcgcttag atgtcaatac
     1501 agccaccttg gtgggtgtag ggtcttccat ttgtgggggg tctgctattg cagcgacagc
     1561 tcctgtcatt aaggcaaagg atgacgaggt tgctaaggca atttcagtca tttttctctt
     1621 taatatgtta gcagctttgc tatttccaag tttaggacaa ttactaggct tatctaatga
     1681 aggttttgct atttttgctg ggacagctgt taacgacacc tcttccgtga ctgcaacggc
     1741 gacggcctgg gatgcccttc accattccaa tacactaaat ggcgcaacca ttgtcaaatt
     1801 gactcgcacc ttggctattc ttccaattac tttaggttta tccctttacc gagcgaaaaa
     1861 agagcacgac atcgttacag aagaaaactt tagccttagg aagtcattcc ctcgtttcat
     1921 cctcttcttt ttattagctt ccctcatcac gacattgatg accagtttgg gagtttctgc
     1981 cgatagtttc cattccctaa aaaccttatc aaaattcttt atcgtgatgg ctatggcagc
     2041 tatcggttta aatacaaacc tggttaaact gattaagatg ggcggtcagg ctatcctttt
     2101 aggagctatt tgctgggtag ctatcaccct tgtcagttta gccatgcaat taagtttggg
     2161 catttggtaa tcagacacga gaaatcagtt tgactgattt ctttttttgt atcttatttg
     2221 tgtagaattg tctacatttt aaagagaata atgcatttta aaaacgtttt catttgataa
     2281 aataaaccta tcgttaaacc agttcagtaa ggacaactgg ttgagataag caattaccgt
     2341 ttactcagcg gtttttgtta atagaggagg ataggaatga aacgaaaatt tctcattggg
     2401 agtcacggca gactagccag tggtttgcaa agctctattg acattttagc aggtatggga
     2461 caggcacttg aaaccattga tgcttatgtt gatgatagtg attatactag ccagattgat
     2521 gactttatcg ctggggtagc agcagatgag cagggcctta tttttactga tttgttaggc
     2581 ggcagtgtga atcagaaaat ggtaaccgct gtaatgaaca gtggcaaaga caatatcttt
     2641 ttaatcacaa acagtaactt agccacttta ttgtcgttgg tatttttaaa accaggcgaa
     2701 gcgcttacta aagatgaaat tgtaaccgtt atcaatgaat cgcaagttca gttagtggat
     2761 ttggtccctg agacaaattc agaagatgac ttttttgatt aatatctagg aggaagacaa
     2821 atgattactc aaattcgtgt tgacgaccgt ttgattcacg ggcaagtggc agttgtatgg
     2881 accaaagagt taaatgcgcc acttttagta gtggctaatg atgaagctgc aaaaaatgaa
     2941 atcacacaaa tgacgcttaa aatggctgtg ccaaacggca tgaaactgct tattcgttca
     3001 gttgaagact cgattaagct ctttaatgat ccacgcgcaa ctgacaagcg tatttttgtg
     3061 attgtcaatt ctgttaaaga tgcttgtgcc attgctaaag aagttccaga cttagaagct
     3121 gttaatgtgg ctaatgtggg gcgctttgat aagtcagatc cagcaagcaa ggttaaggtg
     3181 acgccaagtc ttttattaaa cccagaagaa atggcagccg caaaggaatt agtcagttta
     3241 ccagaacttg atgtctttaa ccaagtctta ccatcaaata ccaaggtcca tttgagccaa
     3301 ttagtcaact aaagagaggt aaaaaagtat gttagtacca gcaacaatgg cagctttagc
     3361 tgtattgatt tgttttgggg gaaattattt aaccggtcaa agcatgatgg aaagacccct
     3421 agtagttgga ctggtcacag gtcttctttt aggagatatg aaggtcggta tcttaatggg
     3481 ggcctctcta gaagctcttt tcctaggaaa tgtgaatatt gggggtgtta ttgcagctga
     3541 gcctgtaaca gcgactgcca tggcaacaac ctttaccatt atttcacata ttgaccaaaa
     3601 agcagccatg accctagctg ttccaattgg aatgttagca gcctttgtgg ttatgttttt
     3661 gaaaaacgtc ttcatgaata tctttgctcc aatggttgat aaagctgcag cagctaacca
     3721 tcaaggtaaa ctagtgatgc tccactatgg cacttggatt atctattact taatcattgc
     3781 ctctatttct ttcattggta ttttagtagg tagtggacct gttaatgcct ttgtggaaca
     3841 cattcctcaa aatctcatga atggcttgag tgctgcggga ggccttcttc cagctgtcgg
     3901 ttttgccatg ctgatgaaat tattgtggac caacaaatta gctgtttttt acctattggg
     3961 ctttgtctta acagcttatt tgaaattacc agcggttgca gttgctgccc taggagcagt
     4021 tatttgcgtc attagttccc aacgtgatct agaattagac gcaattacta gaggtgcaat
     4081 tagtaaacaa acaacctttg actctaaaga atcagaagag gaggacttct tcgcatgaca
     4141 tcacaagata atttgactaa agaagaccgt aaaatgcttc gctcagtctt ttggcgctca
     4201 tggacgatga atgctagtcg tactggggca acacaatacc acgcagtagg ggttatttac
     4261 actttactac cagtcatcaa tcgtttttat aagactgata aggataaagc agaggcactg
     4321 gtccgtcata caacatggtt caatgccacc atgcatatca ataactttat catgggtctt
     4381 gtggcatcga tggaaaagaa aaacagtgaa gatcctgatt ttgatgctag tgctattacg
     4441 gcggtaaaag catctctaat gggacctatt tccggcgttg gagattcctt cttctgggga
     4501 attttaaggg ttattgctgc aggaattggg atttccttgg caagtgcagg ctcagccatg
     4561 ggagctgttg tcttcttact cttgtacaat attcctgctt ttattattca ctactatagc
     4621 ctttatggtg gttattctgt aggtgcagga tttatcaaaa aactttacga atctggtggt
     4681 ataaaaatcg tcactaaaac ctcaagcatg cttgggttaa tgatggtagg ctcaatgact
     4741 gcttcaaatg taaaatttaa aacgattctt acagttgctg cgaaaggtgc caaagaagca
     4801 gcttctattc aagattacct tgaccaattg tttattggta ttgtaccatt aatggtaaca
     4861 ctagcagctt tttggcttct acgaaagaaa gtgaatatca actggattat gtttggtatc
     4921 atgttccttg gcattatcct tggactttta ggtatttgct aataatctcc tagcaataaa
     4981 ggtaagtaag acaagttttc ttgttttgct tacctttttc cttttaagat gatgagactt
     5041 gttttgatga aaaacgtagt agcattaaga aatttgttat aatgaaagga gcttaagatg
     5101 cgaggtgaac aggtggaaga acattttaaa aaacaattac aagatgatat ttctagacat
     5161 ttttcgtacc aatcgttaat gttatcattg ttgctaattg gtctttttat tattttttca
     5221 ttagcgccac aacaattagg cctctatcgt gatatcaatg ccactgcaac ccgttatcac
     5281 cgtttgatta gcaaacaaga agccttgctt gatgacttag ggaaaaatag cttactacct
     5341 tttttaaata aaaacctcag cactgctgat ttaagcaagc actattttca tttgcgccat
     5401 agcagccaaa cgtcaccaga acttttacta ttttcaccta gtcaagacct tttatttgct
     5461 agtaacccac atttaggaaa tgtttttagt aaatctgttt atattcaaga agtcttgaga
     5521 gcagctcatc ctccaaaaac cttgtttaaa gttgctatgg atagtgaaga tggtcactac
     5581 ttgatgatca ttaagccaat gattgatcaa aaccaactaa agggatatgc ttttttagtg
     5641 atgagtggca aagattttct tcatcctaca aaaacattga cgtcagagtt ggtcattgct
     5701 gataagctgg acaatacgtt tacgttttcc aatcgtgagt ttatagcatc tagtctagat
     5761 aagatcaata gccagtattt acaccattat tttgtttttc aagataatcg agcctttatc
     5821 acaagaaagg ttgccttaca aggaggtctt tggctttaca tgtataggcc cttgattcca
     5881 atggtatcgg tgatgttatt ttcacttatt tcatcagctg ttatctttgt gatcttgcaa
     5941 cgtaaatcaa gtggtttagc taaccgaatt gcagctaaaa attcaagagc aatcaatcaa
     6001 atggttagag atatgagtgc gatctctcgg caagaaaaaa gacgtattga ccttgagagt
     6061 caagatgaat ttcaatattt atctgatcaa atcaatcaaa tggtagagcg attgcaacag
     6121 ttacatgata aaacgttaga tttggaaact caaaaattat tatttgaaaa acggatgtta
     6181 gaagctcaat tcaatccgca tttcctctac aatacgctag aaaccatttt gattacgagc
     6241 cattatgatt ctgccctaac agaaaaaatt gttatccaat tgacaaaatt gttgcggtat
     6301 agtctcacgg attctagcaa acctgtcttg ctcaaagatg atttaagtgt catcgagtct
     6361 tatttagtga ttaatcaggt gcggtttgaa gaattgcaat atagcattaa cctatcccca
     6421 gaccttgata gtcttgcagt gcctaaattg ttcttgttac ctttgataga aaatgccatc
     6481 aaatatggct tgaaagaacg acacgatgtc aagattaaca ttgcttgtta ttatcaagat
     6541 gaccacatta ttttttctgt gcgagataat ggttcgggaa ttgatgctca tcaccaaaaa
     6601 gtgattcgag agcaattgga agctggagag tcacaccatg ggttaattaa ctcttatcgt
     6661 cggcttaagt atcatttttc agaagtatcc ttggtttttg atcaaggtga taaacagttt
     6721 aatgttagtt accatgttaa ggagtagtct atgtacaaat tagtcattat tgaagatgaa
     6781 catattatta ggaaatggtt gcgatacgct attgattata aagctttaga tattttggtc
     6841 attggcgagg ctaaagatgg caaagaagga gctgttttaa tcaaagagag tcaaccagat
     6901 atcgttttaa ccgatattaa catgcccatc atgacagctt ttgacatgtt tgaagcaaca
     6961 aaagatcaaa cttacgccaa aattatttta tctggctatg ccgattttcc aaatgcaagg
     7021 tctgccatac actacggtgt acttgaattt ttaacaaaac cgattgaaaa agcagctctt
     7081 tgggaatgtc ttcaaaccat tattgctaaa atagaaaagc aaaaggggtc taatcaaaaa
     7141 acagatgctt gcgtctatat tcccttaccc cagatgactg atcagattcc tgaagtagtc
     7201 aaagatattt tggagtgggt acatgctcat tttcaagaca agatcagcac gagccgccta
     7261 gctcatgact tagggtatag tgagagttat atctatcaaa atatcaaaaa gcatcttcag
     7321 atgcctttaa gtgattacat taatcaatat cggattaatc aggcaattca attgatgcaa
     7381 caagaaccag atttaatggt atatgaaata gcacaagctg taggtattta tgactatcgc
     7441 tattttgata gggtttttaa aaagtatcta ggacaaactg taaaggcttt taaagaagag
     7501 cattttatga aagataccga taggagtaag ccatgttaaa actcaaacgc aaatggctat
     7561 taagcttttt gttagtaata attattctag caatcgttaa cattgcaatg tatatattct
     7621 catcgtcaaa aaaagatagt gctaaagaat tagttatctt gactcctaat agccaaacta
     7681 ttttaacagg gactattcca gcctttgagg aaaagtatgg ggttaaagta agattaatcc
     7741 aaggtgggac gggccaactt attgatcaat taggtcgaaa agataagcca ttaaacgctg
     7801 atattttctt tggtggcaat tacactcaat ttgaaagcca taaagattta tttgaatcct
     7861 atgtttctcc gcaggtttct actgtcattt cagattacca attgcctagt catcgtgcaa
     7921 ccccatatac gatcaatggc agtgtactga ttgttaataa cgaattagca agaggacttc
     7981 atattaccag ttatgaggat ttgctacaac cagctttaaa aggcaaaatt gcttttgctg
     8041 acccaaatag ctcatctagc gctttttcac aattaacaaa catcttactg gctaaaggag
     8101 gctatacgag ctcagaagct tgggagtatg tgaaacgttt attactgtct atgaattcta
     8161 tcagagcaac aagttcttca gatgtttacg aatctgttgc agaaggtaaa atgattgttg
     8221 gtttgaccta tgaagaccct tgcatcaatc tgcaaaaaag cggtgcaaac gtttcgattg
     8281 tttatcctga tgaggggaca gtatttgttc cgtcatcagt cgctattatc aaaaaagcaa
     8341 aggcaatgaa agaagctaag caatttatta attttatttt atcatcagat gtacaaaatg
     8401 cctttgggca gtcaactagt aatagaccta tccgacgaga tgctcaaacg agtcatgaaa
     8461 tgaaaccatt agatgaaatt attactttaa aagaagatta cggatatgtt actagacata
     8521 agaaaaaaat attgaatacc tataatcgac tacatgaagc attagaaaga ggaaagtaga
     8581 ctctaggctt gttgttgcta tactagtagt gttacaaaat agcgtagtca ttttttgaaa
     8641 tcgatttcat aatctggtag actaaggtta tcacgaaaag gaagctatat gtgatggctt
     8701 atcaaactat ttacccttat acaaatgaag tccttcatac atttgataat atgaccgatc
     8761 aaggtttggc agatgtcctt gaaagagctc accttctcta taaaaaatgg cgcaaggaag
     8821 atcatttaga agaacgtaaa gcccagcttc atcaagtggc taatattctt cgtcgtgacc
     8881 gcgataaata cgctgaaatc atgaccaaag acatgggaaa actgttcaca gaagcccaag
     8941 gtgaagtaaa tctttgtgcc gatattgctg attactacgc tgataaggca gatgaatttt
     9001 tgatgtctac gccactagaa acggattcag gtcaagctta ctatttgaaa caatcaactg
     9061 gtgttatcct agctgttgag ccttggaatt ttccttacta tcaaatcatg cgggtctttg
     9121 cgccaaactt tattgttgga aacccaatgg ttttaaaaca cgcgtccatt tgcccacgct
     9181 ctgcccaatc tttcgaagaa ttagttcttg aagctggtgc tgaagcaggt agtattacca
     9241 atttgtttat ttcttatgac caagtatcac aagtgattgc tgataaacgt gtggttggtg
     9301 tctgcttgac aggttccgaa cgtggaggag ctagcattgc agaagaagct ggtaaaaact
     9361 tgaaaaaaac aacccttgaa ttgggtggcg atgatgcctt tattatcctt gatgacgcgg
     9421 attgggatca attagagaag gtgctttact tctctcgtct ctacaatgca ggacaagtat
     9481 gtacctcatc gaaacgtttt atcgtgcttg acaaagacta tgaccgtttc aaagagttat
     9541 taacaaaagt cttcaaaaca gctaaatggg gtgacccaat ggatcccgaa acgacgttgg
     9601 cgccattatc atcagctcaa gctaaagcag atgttcttga ccaaattaag ttggccttgg
     9661 atcatggtgc ggagttggtt tatggtggtg aagcgattga tcatccaggt cattttgtca
     9721 tgccaaccat tattgctggc ctcacaaaag acaaccctat ttactatcaa gaaatctttg
     9781 gcccagtcgg tgaaatctac aaagtgtctt ctgaagaaga agcgattgaa gtggcgaatg
     9841 attctaacta tggccttgga ggtactatct ttagtagcaa tcaagaacat gcgaaagccg
     9901 tagctgctaa aattgaaact ggtatgtctt ttatcaactc aggctggaca agtcttccgg
     9961 aactcccatt tggtgggatt aaacattcag gctatggccg tgaattgagt gagcttggct
    10021 ttacatcttt tgtgaatgaa caccttatct atattccgaa taaaacgaat aatagcaata
    10081 cgaaagtttg atctagattg ttaaaggaga tctgctcgcc ttaataaaca atcaaggcgt
    10141 tacactcttc ttttttaaag tcaaaatttt aaaaatttga taaactagta acatgaacga
    10201 actgattaaa cataaactag aactcttacc agacagccct ggctgttact tacataaaga
    10261 taaagaagga actattatct atgtcggtaa ggccaagaat ttgaaaaaac gcgtccgatc
    10321 ctattttcgt gggagccatg ataccaaaac agagttatta gtatctgaga ttgtagattt
    10381 cgaatatatt gtaacagagt cagataccga agcgcttttg ttggaaatta acttgattca
    10441 aaaaaatatg cctaagtaca acatcaagtt aaaagatgat aaatcttatc cctttctcaa
    10501 aatcacaaat gagtcttttc ctcggttagt gattacaaga tatattaaga aaaatgatgg
    10561 attgtacttt gggccctacc cagattctta cactgctaat gaagttaaaa agttattaga
    10621 taggattttt ccatttaaaa agtgtaaaaa tcctatcaat aaggtctgtt tttattacca
    10681 tttaggccag tgctgtgctc ataccatttg tcatacagac aaggcctatt gggatcgttt
    10741 aattgatgat gttaagcact ttttaaatgg taaagatgac aaaattattg aagatcttcg
    10801 ttctaagatg ttagcagcgt ctgaagaaat ggcatttgaa cgtgccgctg aatatcgaga
    10861 tttgatttca ggtattgcca ccatgcgcac caagcagcgg gtgatgagca aggatttgca
    10921 agatagagat atctttggct attatgttga taagggatgg atgtgtgtcc aagttttctt
    10981 tgtgcgtcaa gggaaattaa ttcagcgtga tgttaacctt tttccctatt ataacgatgc
    11041 agaagaagat ttcttaactt atatggggca attttaccaa gataaacagc atttcatccc
    11101 taaagaagtc tttattccag aagctattga tgaagaactg gtagccgcta ttgtgccaac
    11161 caaaatcatc aaacccaaac gcggtgaaaa aaaacaactg gtagctttgg ctactaagaa
    11221 tgctcgtgtt agtctgcaac aaaaatttga tttattagaa aaagatatca aaaaaacgag
    11281 tggtgctatc gaaaatttag gtcagttact taggattgac aagcctgtgc gcattgaagc
    11341 ctttgataat tctaacattc aagggacaag tccagttgcg gctatggttg tttttgttga
    11401 tggcaaacct agtaagaaag attatcgtaa atttaagatt aaaacagtgg tgggaccaga
    11461 tgattatgcc agtatgagag aagtgctttt tcgaaggtac agtcgggtga aaaaggaggg
    11521 actgcaagct cctaacttga ttattgttga tggaggcgtt ggacaagtca atgtggccaa
    11581 agatgtgata gaaaaacaac ttggactcac tattcctgtt gcgggacttc aaaaaaacga
    11641 taagcaccag acccatgatt tgctttttgg aaacccactt gaagttgtac cgttgccgcg
    11701 ccgttctgaa gagtttttct tactgcatcg gattcaagac gaagtgcatc gctttgcagt
    11761 tacatttcat agacaagtgc gacgtaaaaa ttctttttca tcaacattag atcatatttc
    11821 agggcttggc ccaaagcgaa aacagttatt actaagacac tttaaaacca taacagcgat
    11881 tgcatcagct acctctgagg agattcaagc tttaggtata cctaaaacag tagttgaagc
    11941 aatacagcaa cagataacag acaataaaaa tgatagatcg tctccttaaa taagtgttat
    12001 gttttcagta ctgatgaggt aaaaaggcgc tacttgttac gcacgacatt tcagttcgtt
    12061 attttgaaac tttcagaaag ttgcgaagtg tagtgagttt atgattttaa aaactatttt
    12121 atggtaaaat aaaatggtat taaaaaaaac agatttagat aggaagtttt gaaatgaaat
    12181 ttctagagtt aaacaaaaaa cgccatgcca ttaagacctt taatgaccag ccagttgact
    12241 acgaggattt gcgaacagcc attgagattg caaccttagc acctagtgcc aataacattc
    12301 aaccttggaa atttgtagtc gttcaagaga aaaaagctga gttagcaaaa gggttacctc
    12361 tagcaaataa agtgcaggtt gaacaggctc aatatgtagt ggcgctattt tcagacactg
    12421 atttagcttt acgttctcgt aaaattgccc gtatcggtgt caaatcatta ccagacgact
    12481 taattggtta ttatatggag actttgccac cacgttttgc tgcttttaat gaggttcaaa
    12541 ccggtgagta cttagctatt aatgcaggca ttgtggctat gaacttggtg ttatccttga
    12601 cggatcaaaa gattgcttcc aatattatcc ttggttttga taagtcaacg accaatgaga
    12661 ttttagacat cgatccgcgt tttcgtccag aattattgat tactgttggc tatagtgacg
    12721 agaaaccaga accaagttat cgtttgcctg ttgatgaagt catcgaaaga agatagagtc
    12781 aggacaatta gttaaatgta atgtccagat gcgctactga gcgaccacta ttgttagact
    12841 gatactattt tggcttattt taagttaaac attatcccta aaacgaataa ggagagtata
    12901 atgacaacca ttgattttaa agcagaagtt gacaaacgta aagaagctat gctagcagat
    12961 ttagttgacc tattacgcat taattcagaa cgcgatgacc aattagctga tgataaacac
    13021 ccatttggcc caggtccagt taaggctttg gagcatttcc tcgcaatggc tgagcgtgat
    13081 ggctacaaaa cgcgtaatat tgataactat gcaggtgact ttgaatttgg tcaaggtgat
    13141 gaagtattag gaatctttgc tcaccttgat gttgtcccag ctggtagcgg ttgggataca
    13201 gacccttatg agccagtgat taaagacgat cgcatctatg cgcgtgggtc ttcggatgat
    13261 aaggggccaa ccatggcgtg ctactacgct ctgaaaatca ttaaagaatt gggtcttcct
    13321 gtgtctaaaa aagttcgttt cattgttggt accgatgaag aatctggctg gggggatatg
    13381 gattattact ttgcccataa tggcttgaaa aatccagatt ttggtttctc accagatgct
    13441 gaatttccaa ttatcaatgg tgagaaagga aatatcactg aatacctcca tttcgctggt
    13501 gacaacaagg gcgcttttgt gcttcatcgc ttccaaggtg ggttgcgtga aaacatggta
    13561 ccagaatctg ccacagctgt cattacggca ccgcatgacc ttaatgtgct agaagcagcc
    13621 ttggagcaat ttttatcaga acatggtgtt aaaggttcta tgaaggctac tgatggtaaa
    13681 attgaagtaa ctattattgg taagtctgct cacgggtcga ctccagaagc gggtgttaat
    13741 ggtgccacct tgctggctaa attcctgaat caatttacct ttgaaggggc tgctaaggat
    13801 tatttacatg tggcaggtga ggtgcttcat gaagactttg cggcagaaaa actaggcctt
    13861 gcttataccg atgaccgtat gggaaccttg agcatgaatg cgggtgtctt cacctttgat
    13921 aatcaatcag ctgacaatac catcgccttg aatttccgtt atccaaaagg gactgatgcg
    13981 gcaaccttaa aagcaggatt ggaaaaatta ccaggattaa ctaaggtaag cctttctgag
    14041 catgaacata cacctcatta tgtgccaatg gatgatgaat tagtagctac cttacttgct
    14101 gtttacgaaa aacaaacagg tcttaaaggc tacgaacaag ttatcggcgg aggaaccttt
    14161 ggtcgtttgc tagaacgtgg tgtggccttt ggagcgatgt tcccaggtga tgaaaacact
    14221 atgcaccaag ctaatgaata tatgccttta gaaaatattt atcgctcagc agctatttat
    14281 gctgaagcaa tctacgaatt aattaaataa gatgcttatg acagcaaaaa gagctggaac
    14341 actgttccag ctcttttgtg atgattagag actgttgtta tttaccaaga caaaattggc
    14401 taaagagttg ggtaatgagc tcatcaggag cagcatcccc tgtgatttct ccgagaattt
    14461 cccaagttct ggttaaatca acctgtagta aatccactgg catgccaagg gctaaaccat
    14521 cattgacagc ttccaaactt tggactgcct tttcaatcaa agaaatgtgg cgggcatttg
    14581 acaggtaagt ggcatcttgc tctaccaaac cagcgttgtc aaagaaaagc tggttgatgc
    14641 gatcttcgat caggtcaata ttatggttgg ttaacaccga aataggaata aggtccgctg
    14701 gcaactgttc caattcaatc ttttgttcca aatctgtttt attcagcaat ataatgcggt
    14761 tactgtcttg actgagattt aacaaagccc ggtcttggtc ggtcagtttt tcagaagcat
    14821 tcagcacaag aagaacaagg tcagcttctt gaagagcttt tttagaccgt tcaactccga
    14881 tttgttcgac cagatcatct gtctcacgaa taccggccgt atcgacaagt tttagaggaa
    14941 ctcccttgat attaacgtat tcttcaatga catctcgggt ggttcctgca atatcagtca
    15001 caatagcctt gtcttctcgc aacaaattat taagtaagct tgacttaccg acgtttggac
    15061 gaccaataat agctgttgat aagccctcac gcagaatttt accgcgttta gctgttcgaa
    15121 ggagattttc caaaaggctt tggaattctt gtgttttctc acgtagcaga gcagtggtca
    15181 tttcttccac atcgtcgtat tcagggtagt caatattgac ttcgacttga gctaaggtgt
    15241 tgagaatttc ctgacgggtg tcattgataa gctgggaaag ggagccatcc agttgcttga
    15301 ctgcaatcgt catagccttg tctgttttgg cacgaataat gtccatgaca gcctcagctt
    15361 gagtcaaatc aacacgacca tttaagaagg cacgtttggt gaattcgcca ggctctgcca
    15421 ttctagcgcc ttggcgaatc aatagttgca agatttcatt tgtcacagca ataccaccgt
    15481 gcgtattgat ttcaaccaca ttttcacggg taaaggtttt gggggctagc atgactgaca
    15541 ccataacttc atcgataata gttcctgtct taggatcaat gatatggcca tagttaatag
    15601 tgtgtgaggc gacttgctct aagttctttc ccttaaaaac agattgtgca atggcaagcg
    15661 catctgtccc tgataaacga acaatgccaa tagctccttc accaagaggg gttgaaatgg
    15721 cggtaattgt atcaaattct ttagttatac tcatgccatc tattttaaat caagtcctag
    15781 tagaaagcaa ggtattattt tgcatagaaa ataggactag caccattttg agtttagcta
    15841 atactaaaaa aaataaatgt aaaaaaatca tttttttaat aatttttatt gacaatagta
    15901 ttataaaaga atataatgat ataggttttg ataaaaaact gacctaagac agcaggggag
    15961 catgctcata atattcctgc cgaggcacaa aacgtgatta aagaaaataa cgtatttgta
    16021 ctttcgtgtc taggtttagg tgcgattttt tttgtaccta gcccaaaaat aaaaacggag
    16081 gtaaaactaa tgagtgaagc aattattgct aaaaaagctg aacaagtcga acttattgct
    16141 gagaaaatga aagcagcagc aagtatcgtt gttgttgatt cacgtggtct tacagttgat
    16201 caagatactg ttcttcgtcg ttcacttcgt gaaagtggcg ttgagttcaa agttatcaaa
    16261 aactcaattt tgactcgtgc agctgaaaaa gcaggtcttg atgagttgaa agatgtattc
    16321 gtaggaccat ctgcagtagc attttctaac gaagatgtta tcgcaccagc taaagttatc
    16381 aacgacttta ctaaaactgc tgacgcactt gaaatcaaag gtggtgcaat cgaaggcgct
    16441 gtttcttcaa aagaagaaat ccaagcactt gcaacattgc caaaccgcga aggaatgctt
    16501 tctatgcttc tttctgtact tcaagctcca gtccgcaacg ttgcatacgc tgtcaaagct
    16561 gttgcagaaa acaaagaagg cgctgcttaa gtcgtctcag agtagcttaa ggctacgctt
    16621 aacattttaa attaattatt tggaggaaat cacaatggca ttgaacattg aaaacattat
    16681 tgctgaaatt aaagaagctt caatccttga gcttaacgat cttgtaaaag ctatcgaaga
    16741 agaatttggt gtaactgcag ctgctcctgt agctgctgca gctgctggtg gtgctgaaga
    16801 agctgctaaa gattcattcg acgttgaatt gacatctgct ggcgacaaaa aagttggcgt
    16861 tatcaaagct gttcgtgaaa tcacaggtct tggtcttaaa gaagctaaag gtcttgttga
    16921 tggagcacct gctaacgtta aagaaggcgt tgctgctgca gaagctgaag aaatcaaagc
    16981 taaacttgaa gaagctggag caacaatcac tcttaaataa gaagcagata gcaatttgag
    17041 agcgaaatcc cgatttatca gtcttttaga gtttatagcg atttgaagaa actgataaat
    17101 tgatttggtt tcttgccaaa aatcctgccc aaaaaatctt tggcaggatt tttattttct
    17161 ataaaaatta agctgagtag agtggttatt ctatctatat gtgtctagta ataatttttt
    17221 tatgtgaacg agaacatttt aataagtgtt ctcatttttt tattttcagg aggaaaatca
    17281 tgcaaatgaa tgaacagtca tcacgacaaa tggtgattgc catctatctc atttattcca
    17341 actcaaaatg atagtactcc ttggctgttc caagtcgaaa ttgttagcga ttaagaaaac
    17401 ctacgagact atggtttgat cgatgaagtc caacagtctc ccagtgaaaa agggcgtttg
    17461 gctaataaga tttatttagg aaagttggaa catgattcca ccccagtctt aagttcagac
    17521 ggggccagtc tcaaaaacag accagccccg tgttaaattc agcccctagt gagactgaaa
    17581 agagtgaaac tgaaggtagt gaaactaaag agagtaattt agtcattgag gacgaggagg
    17641 aaagaaagga gtgcactagt gtgaaaaaga ctgagggtca ctttacccgt caagttgatc
    17701 agatcaccaa atatgacaaa gattatattt ggagtttggt tcattcccaa ttacgtgaag
    17761 gtggtttatc acaagctgct agtgacttag tcatgagcta ttttgaagaa cgctatgctt
    17821 atgcgctgga acacatacgg ttcgcaagaa cagctgaagc tattgcggaa tatgtcttta
    17881 atggtgtctt atccgaatgg accaagcaac taaggtgaca agaagcgaag tgaggtgagt
    17941 aagatgtttt ggtggctatt attaggtgtt tggggactaa ggacaatttg gttgattatt
    18001 gaagttatca ctgcaccaga aatggaagat tatagttgag taaggacgtt acataagcag
    18061 taaggtcctt ttattttgtc agaaaggaat gagagatatg aaatttttag atttgtttgc
    18121 aggaattgga ggctttcgat tgggtttaat taatcagtgc catgagtgta ttggcttttg
    18181 tgagattgat aagtttgcga ggcaatctta caaagccatc tatgagaccg aaggagaaat
    18241 agaatttcat gacattagac aagtcacaga ccaagacttt agacaactta gagggcaagt
    18301 ggatatcatc tgcggtggtt tttcccttgt caagcatttt cactcgcagg cagacgactg
    18361 ggatttgagg gcactaggag aactctcttc tttgagatta ctcgagcgac caaacagata
    18421 aaaatcatac ccataatcac atccaatcag cgccattgac cgtaattcag ataaaaaatt
    18481 gatatggaat tatgccttgg aacgaaatct tcgtatgatc tcagaccgta tttctaaaat
    18541 agctggggcg aaaattattg aaaagcattt ctcttaccgt gactatcaaa aatataaagc
    18601 gactagccat aagtttgaac taaagcaacg tctttatttt ttgatgcagc agtcaaagtt
    18661 ctttgatgat tttttagaaa aagcagagta attacatgtt catattgatt ttagtcagaa
    18721 gcatagcaga ttcatgatga cggatcgagt aatgaaaaaa ccaattcgag gccgtcaact
    18781 cagtaaacga gatttatatg atgaagaatt ttttcgtaca cattttgcca agatagaaat
    18841 tgaaagtcga ttagaatttt tgttgaaccg tgccaattca ttagaggagc tactattaaa
    18901 agcaaaagaa gtgaatctaa ccattgactt aaaacaaaaa atgtaacttt tatcctagaa
    18961 gaagatactc aaaagataag tttaggtcat aaaaaaataa gcgataagaa attatatgat
    19021 gtcaattttt tcaagattac tttaaaaaat aaggaagtcg gtgtttcaga tcgattagaa
    19081 agtctacaga aacaatacat gcttttcaag aagaacgaga taaagagaag gtatccactg
    19141 aagagagtaa ggaagtcttc aagaaataca aggggcaacg agataccatc catgagtttg
    19201 aagttgaact tgtggaacat caaattgaga ggttaattgc tgaggacatt tatatcaagg
    19261 tgtcttttgg tgtaaagcag agtggtctta ttttcattcc taactatcaa ttggatatta
    19321 ggaaagaaga aaatcataaa aaatataaag tctatattcg tgagaccgca caattcttca
    19381 tttacaacaa ggaggcgtct gaacttaatc gctatatgcg agggcatgag ctcatttgcc
    19441 agttaaccaa tgatagcaaa agtattccaa aaagaagacg acaaaccatt gatacactta
    19501 agaaaaagat tgaagaaata agtctcctca ttgagttaga tacggagaat aagccttatc
    19561 aagatattaa agatgacatt gttaaagata tggctcaatt agatttgacc attacagagt
    19621 tgcaggacca tattgctcat ctcaataagg ttgcggaggt cttgcttaat ctgaacaaca
    19681 acgatataga gaaccgccgt ttggccagat atgactatgc caagatgaac ttgactgcag
    19741 ctataaaaat agaagaagtt gagaaagaga ttgaaacttc tcaaaatgaa cttaatatat
    19801 ccatagatga gtatgaatat ctagtaagaa ggttggaaaa gtttggagag atcttgagtg
    19861 atagcaaaat tatcgatact tctcgaaatg aaatacaatg ggagtaatta tgatataatt
    19921 tgggtggtag caatttttat atcagatatt aaaatctagt tgatgtttcg taaataacta
    19981 tattaaagaa atgattcctg ccgcttacat tgagaatagt ttatttgtaa gtatttcatt
    20041 atttaaaagg ggtaataatg tataagattt tagccataga tgatgataaa gaaattctga
    20101 agcttatgaa gactgctttg gagattgaaa attaccatgt tataacctgt caagagatag
    20161 aattaccaat agtttttgat gattttaaag gatatgattt gatcttattg gatatcatga
    20221 tgcctaatat aagtggaact gagttttgtt ataaaattcg ggaagaagtt cattctccaa
    20281 ttatttttgt tagtgcttta gatggcgata atgaaattgt ccaagcttta aatatagggg
    20341 gagacgattt tattgtgaaa ccatttagct taaaacaatt cgtagctaaa gttaactctc
    20401 atttgaagag agaagagaga gcaaagataa agaatgaggc tgaggagaga gtgaagcgaa
    20461 gttttccacc tatagaaatc tatctagagg aacgtatgtt atatattgat aaacagccgt
    20521 tattcctgac ttatagagag tacgaaattt tagaattact gtcacgtcat ccgtataaag
    20581 ttttcacaaa agaagagata tatgaacaag tatatagcga tgaagcttca gcattgtttc
    20641 att
//
LOCUS       DAUGOH010000029        20549 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUGOH010000029 DAUGOH010000000
VERSION     DAUGOH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20549
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.029"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            530..919
                     /locus_tag="VH957_001213"
     CDS             530..919
                     /locus_tag="VH957_001213"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEQ8559125.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            1013..2065
                     /locus_tag="VH957_001214"
     CDS             1013..2065
                     /locus_tag="VH957_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8559126.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2204..3736
                     /locus_tag="VH957_001215"
     CDS             2204..3736
                     /locus_tag="VH957_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559127.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGVPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3729..4793
                     /locus_tag="VH957_001216"
     CDS             3729..4793
                     /locus_tag="VH957_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559128.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4795..5751
                     /locus_tag="VH957_001217"
     CDS             4795..5751
                     /locus_tag="VH957_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559129.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5969..7687)
                     /locus_tag="VH957_001218"
     CDS             complement(5969..7687)
                     /locus_tag="VH957_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8559130.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSSGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENTALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7863..8432)
                     /locus_tag="VH957_001219"
     CDS             complement(7863..8432)
                     /locus_tag="VH957_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8559131.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8490..9035)
                     /gene="coaC"
                     /locus_tag="VH957_001220"
     CDS             complement(8490..9035)
                     /gene="coaC"
                     /locus_tag="VH957_001220"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEQ8559132.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(9028..9720)
                     /gene="coaB"
                     /locus_tag="VH957_001221"
     CDS             complement(9028..9720)
                     /gene="coaB"
                     /locus_tag="VH957_001221"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEQ8559133.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKRLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9901..10752
                     /locus_tag="VH957_001222"
     CDS             9901..10752
                     /locus_tag="VH957_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEQ8559134.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDRNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10749..11948
                     /locus_tag="VH957_001223"
     CDS             10749..11948
                     /locus_tag="VH957_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEQ8559135.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVINQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNIAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11945..12943
                     /locus_tag="VH957_001224"
     CDS             11945..12943
                     /locus_tag="VH957_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEQ8559136.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12985..13317
                     /locus_tag="VH957_001225"
     CDS             12985..13317
                     /locus_tag="VH957_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEQ8559137.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13310..14122
                     /locus_tag="VH957_001226"
     CDS             13310..14122
                     /locus_tag="VH957_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEQ8559138.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            14115..14996
                     /locus_tag="VH957_001227"
     CDS             14115..14996
                     /locus_tag="VH957_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEQ8559139.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            15043..16062
                     /locus_tag="VH957_001228"
     CDS             15043..16062
                     /locus_tag="VH957_001228"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8559140.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KSTYQPAIEALHHLGATGVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            16190..17860
                     /locus_tag="VH957_001229"
     CDS             16190..17860
                     /locus_tag="VH957_001229"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8559141.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            17945..19522
                     /gene="cls"
                     /locus_tag="VH957_001230"
     CDS             17945..19522
                     /gene="cls"
                     /locus_tag="VH957_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEQ8559142.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGRWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLKQRP
                     WYQKLIGLLVRTIAPLL"
     gene            19861..20199
                     /locus_tag="VH957_001231"
     CDS             19861..20199
                     /locus_tag="VH957_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559143.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
BASE COUNT         6302 a         3481 c         4246 g         6520 t
ORIGIN      
        1 atgtatttta actgaaaaag gctttcataa ttttaaaaaa atgttaaaat aggtgtataa
       61 caactgatta ccaagagatt attatcatta tcttctaagg tgtcattgtt atggtgacaa
      121 tcaaccatac gctactaaag ataggtagcg ttcgatcaca gattgatcaa gtgattgata
      181 cagatattta taattttaca aatatctgta tcaatccatg ttaaatagtc tatgcttcta
      241 aggtgtcgac gttaatgtac tgacgggacc gttatagtct ttctttttgg agaaacgtcg
      301 gataccagtg aactagttga agttaaagat gttaattcaa acagtgctga agagattgat
      361 atcgttttga acggtcgttt acttcaaagc aaagaaatta ccagtctatc gaagatgata
      421 taagtgctaa agttagatca cgttaattat ctatcaagtc gggtgcatat ttcgttaaag
      481 tatctacagg ggtttcaata gatgtagcta ttatgaaagg tgatgttaaa tggggactac
      541 tgatttagtt agttgtgctg tacaagctag tgagtatgct tatgtccctt actctcattt
      601 tccagtagga gcagctttaa aaacaaaaga tggaacgatc tatactggct gtaatattga
      661 aaatgttagt tttggtctga caaattgtgg agagcgaaca gctatattta aagccatatc
      721 tgatggtcat aaagaattgg ttgaaattgc tatttatgga gaaactatgc aacctgtatc
      781 tccttgtggg gcttgtcgtc aggtaatggc agaatttttt gctccttctt ctttagtcac
      841 tttaattgct aaaaatggtc aaactgttga aatgactgtt ggagatttac tcccctattc
      901 ttttacagat ttaatataat ctgctttaat ttctgttatc tagccgtctt ggctttatat
      961 ttactttcag caacttattt gctagaaatc ttttttagga gggttcatat tcatgaacaa
     1021 gaaatttatt ggtcttggtt tagcgtcagt ggctgtgctg agtttagctg cttgtggtaa
     1081 tcgtggtgct tctaaaggtg gggcatcagg aaaaactgat ttaaaagttg caatggttac
     1141 cgatactggt ggtgtagatg acaaatcatt caaccaatca gcatgggaag gcctgcaatc
     1201 ttggggtaaa gaaatgggcc ttcaaaaagg aacaggtttc gattattttc aatctacaag
     1261 tgaatctgag tatgcaacta atctcgatac agcagtttca ggagggtatc aactgattta
     1321 tggtatcggc tttgcattga aagatgctat tgctaaagca gctggagata atgaaggagt
     1381 taagtttgtt attatcgatg atattatcga aggaaaagat aatgtagcca gtgttacctt
     1441 tgccgaccat gaagctgctt atcttgcagg aattgcagct gcaaaaacaa caaaaacaaa
     1501 aacagttggt ttcgtgggcg gtatggaagg aactgtcata actcgatttg aaaaaggttt
     1561 tgaagcagga gttaagtctg ttgacgatac aatccaagtt aaagttgatt atgctggatc
     1621 atttggtgac gctgcaaaag gaaaaacaat cgcagcagct cagtatgcag caggtgctga
     1681 tgttatttac caggcagcag gaggcactgg agcaggtgta tttaatgaag caaaagctat
     1741 taatgaaaaa cgtagtgaag ctgataaagt ttgggttatt ggtgttgacc gtgatcaaaa
     1801 agacgaagga aaatacactt ctaaagatgg caaagaagca aactttgtac ttgcatcatc
     1861 aatcaaagaa gttggtaaag ctgttcagtt aatcaacaaa caagtagcag ataaaaaatt
     1921 ccctggagga aaaacaactg tctatggttt aaaagatggc ggtgttgaaa tcgcaactac
     1981 aaatgtttca aaagaagctg ttaaagctat taaagaagcg aaagcaaaaa ttaaatctgg
     2041 tgacattaaa gttcctgaaa aatagtgttt aagaacaaga agcgcgacct ttgtcggtcg
     2101 ctctttttaa actgagataa tttttatctc agtaaagttt gtgataggtg atagatcata
     2161 ggctttactg aaataaaaga ttgcattgaa aggaaatgat cctatgacac agcatgtcat
     2221 tgaaatgaga gaaatcacga aaaaatttgg tgattttgtc gcaaatgacc acattaactt
     2281 aaatgtcaga aaaggtgaga ttcatgcctt attgggtgaa aatggggcag gtaaatcaac
     2341 tttgatgaat atgctagctg gtctcttaga gcctactagt ggagaaattg tcattaatga
     2401 caagccagtt caaattgatt cgccatctaa atcagctaag cttggtatcg gaatggtaca
     2461 tcaacatttc atgttagtag aagccttcac ggttgctgag aatattattt taggaaatga
     2521 agtagtaaaa aatgggtgct tagatcttaa ccaagcatcg aaagatatta aggtactatc
     2581 cgaaaaatat ggccttgcaa tcaatccatc agctaaagtt tctgatattt cagtaggagc
     2641 acaacaacgt gttgagattt tgaaaacctt gtatcgtggt gcagatattc ttatctttga
     2701 tgagccaact gccgttttaa cacctgcaga aattaaagaa ttgatgacta tcatgaagaa
     2761 tcttgtgaaa gaaggaaaat caattatttt aattacccat aaactggacg agattcgtgc
     2821 tgtcgccgac cgtgtcacag ttattcgtcg tggtaagagt atcgaaacag ttgatgtggc
     2881 aggagcaact tcacaagatt tagctgagat gatggtggga cgctcggttt cctttacaac
     2941 tagcaaaaaa gctgctgaac caaaagatgt ggtcttatcc atcaaaaatc ttgaagtaga
     3001 tgaaaataga ggggttccag cagttaaggg gctatctcta gatgtccgag ctggtgaaat
     3061 tgtagggatt gctggaattg acggaaatgg tcaatctgag ttaattcaag ctattacagg
     3121 tttacgtaaa gtcaaatctg gaagtattat gattaaaaac aatgaagtca ctcatttgtc
     3181 ttcacgcaaa attactgagt tatcagtggg tcacgtgcca gaagatcgtc atcgagatgg
     3241 tttgatacta gatctttctt tagctgaaaa tacagcctta caaacctatt acaaacaacc
     3301 tctaagtcaa aatggaatct taaattatac taaaattaat gactatgctc gtcaattaat
     3361 gaaagaattt gatgttcgcg gagccaatga gctagtacca gctagaggat tttctggtgg
     3421 taaccaacaa aaggccatta ttgctcgtga agtggaccgt gatccagatt tacttattgt
     3481 tagccaacca acacgtggtc ttgacgtagg agctattgaa tatatccata agcgtttgat
     3541 taaagaacgt gataaaggta aagctgtcct cgttgttagt tttgaacttg atgaaatatt
     3601 gaatttatct gatcgaattg ctgttattca tgatggtaaa attcaaggta tcgtattgcc
     3661 agaaaatacc aataaacaag aattgggtat tttaatggca ggtggttcaa ttcataagga
     3721 ggaaggtcat gtctaaaaat gcgcaaaaaa ttgctgtacc attgatttct gtcttgctag
     3781 gatttttact tggcgctatt attatggtta tctttggtta tgatcctatc tgggggtatg
     3841 aaggtttatt ccaaattgcc tttggtagtg ttaaaaatat tggagaaata ttccgttcaa
     3901 tggggccatt gattttaata gcgcttggct ttactgttgc tagccgtgca ggcttcttta
     3961 acgttggttt gtctggacag gctttagctg gatggatttc agcaggttgg tttgcactct
     4021 taaatccaga tatgcctcgt ccattattga ttcttatgac agctcttatc ggaatgattg
     4081 ctggtggtat tgctggagct attccaggga tacttcgtgc ttatcttggt acaagtgaag
     4141 ttatcgttac gattatgatg aactacatca ttttatatgt cggaaatgct attgttcaac
     4201 gtggttatcc tgagagtgtc aaacaaagta ttgattcaac tattcaagtt agtgataatg
     4261 ctagttatca aacgcattgg ttatcagccc taactaataa ctctcgtatt aatattggta
     4321 ttttctttgc cattattgcc attgccctaa tctggttctt gcttaacaaa actactttag
     4381 gttttgagat tcgttcagtt ggtctcaacc cacatgcttc agaatacgca gggatgtcat
     4441 caaaacgtac tatcatttta tcaatgatta tctctggagc tcttgcaggt cttggaggag
     4501 tagttgaagg tctaggaacc tttgaaaatg tttttgtaca aggatcttct ttagcagttg
     4561 gttttgacgg tatggcagtt agcttattag cagcaaattc accgcttgga atatttttct
     4621 catcattcct atttggtgtc ttaaatattg gtgctccagg aatgaatatt gcaggcattc
     4681 caccagaact tgttaaagta gtaactgcat caatcatttt ctttgttggt tcacattacc
     4741 tcattgaacg ttacattatt cgccctaaaa aattagtgaa aggtggtaaa taagatgagt
     4801 ttagtaacaa tttttgcctt attggtgtca tctatgctta tttatgcaac accactcatt
     4861 ttcacaagta ttggaggaac tttctcagag cgctcaggcg ttgttaatgt tggtttagaa
     4921 ggtatcatgg tcatgggagc gttctctggg attgttttca acttagagtt tgctgaaaca
     4981 tttggaaaag caacgccttg gatagccgtt ttagtcggtg gtattgttgg tttgattttt
     5041 tctttgattc acgctgtagc aaccatcaac tttcgagctg accacattgt cagtggtaca
     5101 gtgttgaact tgttagcacc ttcttttgct gtcttcttgg ttaaagctat gtacggtaag
     5161 ggacaaacag acaacattca acaatctttt gggaagtttg atttcccagg tttatcacaa
     5221 attcctgtga ttggtgatat tttctttaaa aatactagcc ttattggtta cttcgccatt
     5281 gctttttcgt tctttgcttg gtttttgctt tataaaacca ggtttggtct gcgtttacga
     5341 tcagttgggg aacaccctca ggcagctgac acacttggta ttaacgtcta tttgatgaaa
     5401 tactatggtg tgatgatctc aggttttctt ggtggaatag gtggagctgt ttatgctcag
     5461 tcaatctccg ttaactttgc tgtaacaact atcttaggtc ctggatttat tgctttggca
     5521 gctatgatct ttggtaaatg gaatccagtt ggcgccatgc tatctagtct tttctttggc
     5581 ttatcgcaaa gtttagccgt tattggtgct caattaccat tactagaaaa gattccaacg
     5641 gtttacttac agattgcacc ttatatggta acgattatta ttttagctgc tttctttggt
     5701 caagcagttg caccaaaagc tgatggaatc aactatatta aatctaaata acgttatatt
     5761 agtagtaagc ctcttagtga ggtttaacag cactcctaaa gcaagatagt taggtctagc
     5821 tttaagggtg cttttttggg acttaccgca agcgtttgga ttgccagtca ccatcacaat
     5881 agaagcaaga atagactaaa aagaactaag tcagcggctt agttcttttt gcttgtcttt
     5941 cgtttttact gatagctctt aagttgtttt agccaacaaa ggtattgatt tctgtttcaa
     6001 tgttagcaat tttttcttga gcgatgtcaa gagtatcacc tattgtggca atatagaact
     6061 tgatttttgg ttcagttcct gaagggcgaa ctgcaatcca tgaatcatca gctaacgtgt
     6121 acttcaaaac attacttgga ggagttgtta agttagatat tgttccatca tttttagtag
     6181 cggtttgttt ttggaaatct tctaataata caatatcagt attgttaaat tgttttggac
     6241 cattttcacg gaatttgtcc ataatcttct taatttcagc agctccatcc acacctgaaa
     6301 gtgttactga aatcgttttt tcagcaaaat agccatattc tttgtaaatt tcatcaatac
     6361 catctgcaag tgttaaacca cgcgaacggt aataagctgc gatctcagca accaaaagaa
     6421 ctgcttgaat agcatcttta tcacggacaa atggtttaat aagatatccg aagctttctt
     6481 caaaaccaaa catataggtg tggttatgtt tttcttcaaa ctcttgaatt ttctcagcga
     6541 tgaatttgaa tccagttaaa acgttaaaca ttgtagcgcc ataactttcg gcaatttttg
     6601 ttactaattc tgttgatacg attgatttag cgagagcagt attttctgga agtgttcctg
     6661 ctgttttatg agcttccagg atgtatttcg caataatcgc tccaatttga tttccagaaa
     6721 ggtttttata agaaccatct ggttggcgaa tttcaacgcc taggcggtct gcatcaggat
     6781 cagtagctac taagacatct gcatcaactt ctcgtccgag ttcttcagca agagcaaagg
     6841 cagcttggct ttcagggtta ggcgatttaa cagtagaaaa gtctggatct gccttagctt
     6901 gtgattcgac tacaacaaca gattcaaaac cggcttgagc aagggcacgg cgtgtcaaca
     6961 tctcaccagt tccgtggaga ggagtataga caattttcat gtcttttcca aagttattga
     7021 ttaaatcttg attgatatta acatctttaa cctctctaag atattccata tcaacatctt
     7081 caccgataac ttgaataaga cctgatgatt tgctttcatc taaatcagca agttcaactg
     7141 caaatggatt ttcaatagca cggataaagt ctgttagtgc atcagcatca gctggtggta
     7201 gttgacctcc gtcttgtcca taaactttat aaccattgaa aggtgctgga ttgtggcttg
     7261 cagtaaccat aataccagca taggcattta aatggcgaac agcaaaagag agttctggtg
     7321 ttggacgaag agcttcaaat acgtaagatt taatcccatg ctgtgccaag acctgtgcag
     7381 actcaaaagc aaattctgga gagaagtggc gcgaatcata agcgatggct acaccacgtt
     7441 ttttagcttc ctctccctta gtttcgatta attttgctaa tccttcggtt gcttgacgga
     7501 caacataaat attaatacga tttgtaccag caccaatata accacgcata ccagcagtac
     7561 caaattctaa gtttgtgtaa aaagcatctt cttttgtttt ttcatccatt gatagtaatt
     7621 cttgacgaag atagtcagga agctgctcaa aatctaacca tttttgaaaa ttttctgtgt
     7681 aagtcattga aatactcctt caatatttat aaacgctttc attatatcat tttgaaggaa
     7741 aaaaaacact aattatttgc agctgtttac aaaacttttt ccatattttc aagtagctaa
     7801 tgtaagaaag ttaaaataac caagttttta aaagagaaaa actcggttat tgtgaaagct
     7861 aattaccttt ttagtcttga tagtgttgga ataagtacaa aggtaataat agctgagatg
     7921 atcatctcaa caatagcgtt tgatgagatg atggctgtta gtagtgcttt aatatttcca
     7981 tcaaaaactg tcgcgaaaaa aataaatatc ccagataata caaatatagt atttgttaga
     8041 gaaccaatga taccggatac tattaaacca aactgattag gaatcaattt atagcaataa
     8101 taaggggtaa taccaatcaa aatacgtggg ataatagcaa ttattaaaga agcgaaagtt
     8161 ccatgatcga caaaaggtga aaagagataa tttgtaggca gtagaatgat ggtatttgta
     8221 atgacactta taatccccat taatcctcct aaaatagcac ctatccttgg gccatataag
     8281 acagaagcaa taataactgg gatatggaca agcgttggtt tgattggaat aggccaaata
     8341 ttaaagacaa gactgctcac aaaatgaatg actaacatga tggcaaaaaa gatagcaata
     8401 cgagaaatat ctgctgattt acggtgattc attttactct ccaaaaaata taatacttaa
     8461 ttctaaaaag gtgatcagaa aaacgactgt taaagtttcc aaatcgtatc aatagtagct
     8521 aagataacat caatatcagc caaagcacca ggtcctttat ctccacaggc taataagcta
     8581 gattttggag gaatttctgt aaaccctatt gtcgataagc gtttaatatt ttcttgggta
     8641 atagggtttt gatacatttt ggtattcatg gctggggcta ttaattttgg tgtggtagct
     8701 ggtagggcaa gagcaacact tgttacaata ttatcagcga atccatatgc tagatgagca
     8761 atagtattag cagaggcagg tgcaacaata aataaatctg tgcgttttgc taattcgata
     8821 tggttgataa cttttgggtc atgctcatcc ataacatcta aatgaatagc attttttgat
     8881 aacacttgca gggttaatgg tgtaataaat tgtgtagcag cctgagtcat tatgatgtga
     8941 acatcatagc caattttagt taattgactc gtaagatctg ctgctttata ggcagatata
     9001 ctaccagaaa cagctaaggt aatatgttta gtcatgtttg gtcatccttt catataataa
     9061 gtcagcaatt gcctctttgg tatctgcaga tgcaacttcg ttattggata tcaaaagagc
     9121 cttgtgcata cctgtttgga tatcaactaa atcattggcg agaatataat cagcatggtt
     9181 tttagctaga cttgctctgg ctactttaat taactcttct tgaggcacat taactagaag
     9241 tttaaagccg actagtttaa tattaggatt ccactgttta acataagaga taactttggg
     9301 tgtttttttc aaaaaaagaa cctgataatc agatgcagat gagattttcg gctcactgtt
     9361 atgttcacat agaaaacaat taaggttatc agcttgagag acttgttcca aatcagtcat
     9421 gtagactgga gtatagtcag aaacagccat actatgaatt agaatgtcat ggtgaggaac
     9481 ctgatctttg agtgcagcca ttaagtcgtt aactgtttcc acttcaataa tccttaggcg
     9541 cttatttggc aggggtttag tggctgtttt agtagtgact agggtaacgt catgatgata
     9601 ttgtaaaaat cgctctgtga ttaattttcc aagttgccca gttgagtgat tagtgatacc
     9661 tcgtactgca tctataggtt cagttgttcc acctgatgtt attattaatt tcatagtcat
     9721 attttatcaa aaaaggagct gatagtaaac ggaagataat gacgccagac attgtcttgc
     9781 gtttgtatta atatggaata gtaatagatt tctagtaatt aaaacgaagt tctggaaagc
     9841 aagacactat agtagctaaa atctaaattt taaggtaaaa tagagcaagc ggtttcaagt
     9901 gtgaaaggaa gaattgtgat aactattaga gatttagcgt cactgccgat ttttgtttac
     9961 ggtgatagaa ataaaaaagt tccaggagct ttgagtcctt ttgtgtggac agaggtgttt
    10021 ttaaaaacta tcaatcaaga acctaatcaa ctgatcttac atatttggcc gatgacaaga
    10081 acagttatat tagggatgtt agatagacag cttccctact ttgagctggc taaaacagag
    10141 attggcaata atggttatgt tcctgttact cgtaatattg gcggtttggc tgttgtcgct
    10201 gatgatggga ttttgaattt ttcgcttgtt attccagacc atttttcgga atctatcagt
    10261 attagtaatg cttatttaat aatggttgat gtcattagag agagtttttc ggattattat
    10321 cagcgtattg aatatcacga aattaaaaat tcttattgcc ctggtaattt tgatcttagt
    10381 attgcaggcc gcaagtttgc aggtatcgcc cagcgtcgta tcaaaaaggg aattgttgtg
    10441 tctatttact tgagcgtttg tggggatcaa gcagcgcgtg gtcaactcat caaggatttt
    10501 tatgaggccg gaacacaagg agaagttacc aaggttaatt accctcaaat tgatccagaa
    10561 tgcatggcaa ctctttcaga actccttgag acgcctttta cagtggcaga agtccttgaa
    10621 cgtcttcgat tgaccttgcg acagcttggc ttttccctca cggaaaaaag tccagatcaa
    10681 gccttactga ctaattttga tgctgtctat gaacggatgc agctagaagt cgtcagaaag
    10741 gaaggcaaat gaaagaaaga tttagtcctt tatttgagcc tttgactttg ccaaatggga
    10801 gtcaattgga taatcgcttt gttttgtctc ctatggtgac caactcatcc acaaaagacg
    10861 gttatgtcac ccaagatgat gtatcctatg ctttgagacg agcagcttct gcccctctac
    10921 aaattacagg agcggcctat gtggatcctt atggtcaatt gtttgaatat ggttttagtg
    10981 ttacaaaaga tgccgatatt tctggcttga aagagctagc tcaagcgatg aaggcaaagg
    11041 gagctaaagc tgtcttacaa ctgacccacg ctggccggtt tgctagccat gccttgacta
    11101 aatatggctt tgtctatggg cctagttaca tgcagttgag atctccccaa cctcatgaag
    11161 tcaaaccttt aacaggtcag caaatagagg aattgattgc agcttacgct caggccactc
    11221 ggcgggcaat tcaagcaggc tttgatggcg tggaagtatc ttcggcgcag cgcttattga
    11281 ttcaaacgtt cttttcgact ttttcgaaca agaggacaga tagttatggt tgtcaaacac
    11341 tttttaatcg ctctaagtta actttagctg ttttgcaagc tgttcaacag gtgattaatc
    11401 aagaagctcc tgatgggttt atttttggat ttcgtgctac accagaagaa actaggggaa
    11461 atgatattgg ttatagtatt gacgagtttt tgcagttgat ggattgggta cttaatattg
    11521 caaaacttga ttatttagcg atagcaagtt ggggccgtca tgtatttcga aatactgttc
    11581 gttctcctgg cccttattat ggaaggcgag ttaatcaggt agttagagat tatttaagaa
    11641 ataagctacc tgttatggct acagggggaa tgaacacacc tgacaaagct attgaagcac
    11701 tagctcatgc tgattttatt ggagtatcta caccttttgt cgtggatcca gaatttgctc
    11761 ataaaatcaa agaagggtgt gaagagagta ttcatttaag gattcgacct gctgatttga
    11821 aaagtttagc gattcctcag gcttctttca aagatattgt acctttgatg gactacgggg
    11881 aatcattgcc taaagaatca agaactttat ttcgtagtct tactcacaat tataaggaga
    11941 ttaaatgaaa gtcagtattc ttgattatgg ggtgattgat aaagaaaaaa caccccaaga
    12001 agctttatta gaaacgcgct gcttagcaca agtagccgac aaacttggtt ttcatcgttt
    12061 ttgggtagca gagcatcata atatttatgc ctttgcaata agcagtccag agctgttgat
    12121 gatgcattta gcagatcata ccaaacagat tcggataggt tcaggaggta ttatgcctct
    12181 acattatagt agctttaaga ttgcagaatg gataatgact ttagaggcct tgcaccctaa
    12241 tcggattgat ttaggtattg gcaactcttt aggaactacg ttagttcaaa gagctctatc
    12301 aagtatccat tgcaaagaca gctatagtca ggttgtcaca gaattatacc agtatcttaa
    12361 tcctgatcat ttgtcaccac taccgatttt tgttaaccct aggggtaata cttaccctca
    12421 gatttggacg ctaagcaata gtttggagac agcagaactg gctggtcaat taggtttagg
    12481 ctataccttt ggtattttcc cctatatacc aaaagatcct ataacagaag ctaaaagagt
    12541 atcggcacat tatagaaagg cttttaggcc ttcaaagcta ttaaaaatcc ccaagttaat
    12601 attagcagtt tttattgtcc tttctgatac cgacgaggaa gcagaagctt tggctaaacc
    12661 gttggacatt tggatgcttg gtcagcaaga ttttaatgaa tttaagacct accctgatgt
    12721 tgaggaggct agaaactatc acttaacaga gaaacaaaga gaagccattg cagcaaatcg
    12781 tagtcgcatg gttattggat cacctcacac agtcaagaaa caattggata ggctgataga
    12841 agcttgtcaa gctgacgaat tattagccat ccccttagtt cctgaatttg ccaatagaca
    12901 acgaacctta gagctgctag cagacttata cgtgaccatt taaccttacc aaaaacaatt
    12961 ccctaaactg aaaggaaaga aacaatgaaa aaaattgcaa attacttatt aattgagaaa
    13021 acagatgacc gctataccat tagcatgaca ccagaattac aagacgatat tggtactatt
    13081 ggttacgctg aatttacgga taacgaccac cttgccgttg atgacattat cttaaatcta
    13141 gaggcttcta agaccgtcat gtctgtcttg tcaccattgg ctggggcagt tgttgagcgc
    13201 aatgaggcag ccacactaac accaaccctt ttgaattcag aaaaagctga ggaaaattgg
    13261 attgttgtgc taacagatgt tgatcaagca gcttttgatg ccctagaaga tgcctagttc
    13321 atttgattta ttaggggaaa tgattggtct gttgcaaaca gagcagctta ctagttcttg
    13381 ggcctgtccc ttgcctaatg ctttaacaaa gcgacaagac ttgtggcggg cgctcattaa
    13441 ccagcgccct gctttgccct tatcaaaaga ttacttgaat ctggaagatg cttatctaga
    13501 tgattggcgt gcttcttttg ttcctgtatc agtcaaggat tgccaaaaaa ctaattatac
    13561 cagtcttttt ctttaccatg gggatattag gtaccttgct gtggatgcta ttgtcaacgc
    13621 tgctaatagt gagttattgg gatgttttat tcctaaccat ggctgtattg ataatgcgat
    13681 tcatacgttt gccggaagtc gtttacgctt agcttgtcag gcaatcatga ctgaacaagg
    13741 ccgtaaggaa gccattggac aagcaaagct taccagtgct tatcatctac cagcctctta
    13801 tattattcat accgtagggc caagaattac caaaggacac cacgtttctc cgattcgagc
    13861 tgatttgtta gcacgttgtt atcgttctag tcttgatttg gcggttaaag caggattgac
    13921 tagcctagct ttttgctcta tttcaacagg agaatttggc tttcctaaaa aagaagccgc
    13981 tcagattgct attaagacag ttttaaaatg gcaagcagaa catccagaat ctaagacctt
    14041 aactatcatt tttaatacct ttacatcaga agacaaggcc ttatacgaca cttatttgca
    14101 aaaggagaat aactgtgagt aattggacaa cctatcctca gaaaaacctc acccaggcag
    14161 aacaactggc ccaattaatc aaagaagcag atgcacttgt agttggtatt ggagctggca
    14221 tgtctgcagc tgatggtttt acttatatcg ggccgcgttt tgagacggca ttcccagatt
    14281 ttattgctaa gtatcagttt ttggatatgc tgcaagctag tctttttgat tttgaagatt
    14341 ggcaagaata ttgggctttt caaagtcgct ttgtcgcttt gaattatctt gatcagcccg
    14401 taggccagtc ttatcttgat ttaaaagaga ttttggaaac caaagactat catattatta
    14461 ctactaatgc tgataatgct ttttgggtgg ctggttatga tcctcataac atttttcaca
    14521 ttcaagggga atatggtttg tggcaatgta gccagcactg ccatcagcaa acttataagg
    14581 acgatacggt catccgtcaa atgatcgcag agcaaaaaaa catgaaagtc ccaggtcaac
    14641 tgattcctca ttgccctgaa tgtgaggcgc cttttgaaat caataagcgt aatgaagaaa
    14701 aaggaatggt tgaagatgct gactttcatg cccaaaaagc acgttatgag gcttttttat
    14761 cagaacataa agagggtaaa gtgctttatc tagaaattgg tgtgggacat acgacgcctc
    14821 agtttatcaa acaccccttt tggaaacgtg tctcagaaaa ccctaatgcc ttattcgtta
    14881 ccttgaatca caaacattac cgcatccctc tgtcaataag gcgacaaagc ctagaactga
    14941 cagaacacat tgcacaattg attagcgcca caaaaaccat ttaccaaaaa tcgtaaccaa
    15001 agccaataga cggttaatta agagatatag aaggagacta acatgtacct tattgaaccg
    15061 attcgtaacg gtaaacgtat caccgatgga gctgttgctc tagccatgca agtttatgtt
    15121 caagaaaatc tatttttaga tgatgatatt ttatttccct actattgtga tcccaaagtt
    15181 gaaattggaa aattccagaa tgcggttgta gaaactaatc aagagtattt aaaagagcat
    15241 catatccctg ttgttcgccg agatactggc ggtggtgccg tttatgtaga ttctggtgct
    15301 gttaatattt gctacttgat taatgataat ggtatttttg gtgattttaa aagtacctat
    15361 cagcccgcta ttgaagccct tcatcatttg ggagcaacag gggttgaaat gtctggacgg
    15421 aatgacttgg ttattgatgg gaaaaaggta tctggcgctg cgatgactat tgctaatggc
    15481 cgtgtttatg ggggatattc ccttttgcta gatgtggact ttgaagccat ggaaaaagca
    15541 ttaaaaccta atcgcaaaaa aattgaatca aaaggcatca ggtcagttcg tagtcgcgtt
    15601 ggaaacatca gagaacattt agcaccacaa taccaaggta ttacgattga agagttcaaa
    15661 gatttaatgg tttgccaatt gttacagatt gagacgatta gccaagctaa gcgttatgat
    15721 ttaacggaaa aagactggca acaaattgat gctttaacag agcgtaaata tcacaattgg
    15781 gaatggaatt atggcaacgc gcctcaatac cgttaccata gagatggccg ttttaccggt
    15841 ggaacagtag atattcattt agatattaaa aaaggctata ttgcagcttg tcgcatttac
    15901 ggagattttt ttggcaaggc agacattgca gaacttgaag gtcacttgat aggaacacga
    15961 atggaaaaag aggatgtctt agctaccctc aatgcaattg atttagcccc ttatttaggt
    16021 gcgattacag cagaagaatt aggagatttg atattttctt gataaaaaag atacctcaga
    16081 ccggtaaagt gcgattaaaa acgaacaata attgttttaa ttcaaataaa tgtacgtatg
    16141 atatgaattg tgatataatg acgtcattac gtaaaattga ggagtcatca tgaaatcaga
    16201 tatcgaaatt gcccaaagtg tcgccctaca accaatcact gacattgtta aaaaagttgg
    16261 aatagacggc gatgacattg agctttatgg caaatataag gctaaattgt cttttgagaa
    16321 aatgaaagct gtcgaagcta atgagcctgg aaaattaatc ttggtaactg ctattaaccc
    16381 tactccagcg ggagaaggaa aatcaaccat gtctattgga ctggcagatg ccttaaatca
    16441 aatgggaaaa aaaaccatgc ttgccttacg tgaaccctcc cttggtcctg ttatggggat
    16501 taaaggcggg gcagcaggtg gtggttatgc ccaagtattg cctatggaag acattaatct
    16561 tcactttact ggtgacatgc atgccattac aactgctaat aatgcattat ctgctttgat
    16621 tgacaatcat ttgcagcaag gaaacgattt aggaattgat cctcgccgca ttatttggaa
    16681 gcgcgtgttg gaccttaatg atcgcgctct tcgtcaggta attgttggct taggtagtcc
    16741 agtgaatggt gtgccacgcg aagatggatt tgatatcaca gtagcttctg aaatcatggc
    16801 aattttatgt ttggcaactg acttaaaaga tctaaagaaa cgtcttgctg atatcgtcgt
    16861 ggcttatacc tatgatcgta agcctgtcta tgtgcgtgac ttgaaggttg aaggagcatt
    16921 gacattaatt ctaaaagatg ctatcaagcc aaacttggtg cagactattt atggaacacc
    16981 agctcttatt catggggggc catttgctaa tattgctcat ggttgtaatt ctgtccttgc
    17041 tacctcaaca gctttgcgat tagcagatta cactgttacc gaagcaggat tcggggccga
    17101 cctaggagct gaaaaattcc taaatatcaa agtacctaat cttcctaaag caccagatgc
    17161 tatcgtcatt gttgcaacct tgcgcgccct taaaatgcat ggaggtgtcg ccaaatcaga
    17221 tttagccgct gaaaattgtg aggctgttcg cttaggattt gccaacttaa aacgtcacgt
    17281 ggaaaacatg cgccaattca aagttccagt tgtggtggct atcaatgaat ttgtagcaga
    17341 taccgaggct gaaattgcta ccttaaaagc gctttgtgaa gagattaagg ttccagtaga
    17401 attagccagt gtttgggcaa atggagctga gggaggctta gcattagcta aaacagtggt
    17461 tcgtgtgatt gatcaagaag ctgctgacta caaacgtctc tattcagatg aggatacttt
    17521 ggaagaaaaa gtgatcaata tcgttaccca gatttatggt ggcaaagctg ttcaatttgg
    17581 ccccaaggcc aaaacacaat tgaagcagtt cgcagaattc ggttgggata aattgcctgt
    17641 ttgtatggct aagacccaat acagtttttc agataaccca tccttgcttg gagcgccaac
    17701 cgattttgat attaccattc gtgaatttgt tcctaaaaca ggggcaggtt ttattgttgg
    17761 tttaacaggt gatgtgatga ccatgcctgg tttgcctaaa gttccagctg ccatggcaat
    17821 ggacgtagca gaaaatggca cagccctcgg tctcttttag gaaaaattgc tcgaataatt
    17881 cgagcaagcg ctcctttctt cccgctttac tgtgatataa taaggtaaat gagattttgg
    17941 agggatgatt atcaaaaaga aagcaaaagt aaaatatttg ctccataaag ggaaacatgg
    18001 atttttaaga ggaattttta gtagaacaac aatcattgta ttattaatta ttttgcaatt
    18061 agttttctta tttcaatctt atgcctggat ggagcagtac cgtgtttgga taacgattct
    18121 tgaaagtgtc tttgctatta ctattgtttt atatttagtt aatagtgata tggatgctat
    18181 ttcaagaatg acgtggttaa ttttgattat gattgctcca ttactagggt cactgttttt
    18241 aatttataca aaattggatt ggggttacag agggctaaaa caaagaataa atcatcttgt
    18301 agatctgtct gcaccttacc ttagcgatga tgacgctata ttagaggtat taaaggatag
    18361 cacatcaacc acatatcatt tagtacagta cttagaaaga agtcgtggca actttccgat
    18421 ttataataat acaagggtaa cttacttccc aacaggtgaa actttttttg atagtttaaa
    18481 agaacagtta ttcttagcta aaaagtacat ttttcttgaa ttttttatta ttgcagaagg
    18541 ccaaatgtgg ggagaaatcc ttagtattct agaaaaaaaa gtcagtgaag gtgtagaagt
    18601 tagggtgttg tttgatggca tgaacgaact atcaacgcta tcatcagatt acgccaagag
    18661 attagaacaa atagggatta aagctaaatc atttttaccg atttcaccct ttatctctac
    18721 ctattacaat tatcgagatc accgaaaaat tgtcgttatt gatggggagg tatcattcac
    18781 tggaggtatt aatctagcag atgagtacat taatgaagta gagcgttttg gccgctggaa
    18841 agatgctggt ttaatgcttg agggtgaagc aacagacagc tttttaattt tgtttttaca
    18901 aatgtggtct atcacagaaa aagaactgat tattgatcct tatctttcag atcattcttt
    18961 aaaacttcct tcagatggct atgttattcc ctacggtgat tccccgcttg atactgataa
    19021 aataggtaaa aatgtttata tagacatttt aaatcatgct aaagagtacg tttatatcat
    19081 gacaccttac cttattttag atagcgagat ggaacacgct ttacgatttg catcagaacg
    19141 tggagtagat atccgaatta ttatgccagg agtgccagat aagggggtac catatgcctt
    19201 agctaaaacc tattataaag ctttgatgac ttctggagta aaaatttatg agtatcaacc
    19261 agggttcgtt cattcaaagg tatttatctc tgataataca aaagcagttg tcggaacaat
    19321 taacttagac tatcgtagcc tttatcatca ttttgaatgc gcgacttatt tatatcgtgt
    19381 gtcagttatt gctgatattg tgaatgactt taatgaagct caaaagcaat cactattgat
    19441 gacatcagat catttgaagc aacgtccttg gtatcaaaaa ttgataggat tattagtacg
    19501 aacaattgcc cctctcttgt aattttcgta aaatatgtta taatatctgt atgcgatgag
    19561 tcgattgtga ctgcaaagtc acttttgcgc aggggaggtc attaaggcgg gaagccgact
    19621 ttgataatct gtgtgaacca ttttatcaca atcttattta ttaagaatgc cccttggatt
    19681 gagatattct caatcctttt ttaattttat tatcttagtt aaaattcaga atgtatcagt
    19741 gattactgtg tttcaaaata agaaagtagt ttttcgggta tgagtgctat gacttgacaa
    19801 atgctaataa catttgcata atgtaagtag agatgaaaac ttatgaaaag agatgatctt
    19861 atgcaaatta ttaagcgtga tggccacgtt gctgattttg atccagataa aatttatcaa
    19921 gcaattatta aagcagcaag gacggtctat gttattgatg acacgtggcg acaaaactta
    19981 acacatgtca ctaaaaaagt agttattgat ttagaagaag cacatgtaga acgtcctact
    20041 atcaatatgg tccaatccct tgtggagaat cgtttgatgg atgctggata tattaccatt
    20101 gcagaacatt acatttctta tcgtcttcag cgagatttag agcgcaatgg ctatggtgat
    20161 aagattgtgg ttcacttgcg ttttgaacaa ataaaataaa aacgcttcta atggcatttt
    20221 agtgtctttg aggggataag gtttaaatac ctaacagata aaaatctgtt aggtattttt
    20281 ttgctactat taggtgtatt ctatctcaca tagaacttaa gcattcaagc tttaatttaa
    20341 ctttctgttt attttttgct acattttggg aaactcccct cctttcttag ttgaggtgaa
    20401 taaactttta tttgataaat catattttta agtagtctaa aattatgttt ttttaatttc
    20461 aaaatcatgc tttcgtttgt tataaaaacc gatcttccat agttagattt tttatccagg
    20521 caattgaaga ttggggcaac tattcaatt
//
LOCUS       DAUGOH010000030        17648 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUGOH010000030 DAUGOH010000000
VERSION     DAUGOH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17648
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.030"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            442..1791
                     /locus_tag="VH957_001232"
     CDS             442..1791
                     /locus_tag="VH957_001232"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEQ8559144.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(2140..3648)
                     /locus_tag="VH957_001233"
     CDS             complement(2140..3648)
                     /locus_tag="VH957_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8559145.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            4336..5007
                     /locus_tag="VH957_001234"
     CDS             4336..5007
                     /locus_tag="VH957_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEQ8559146.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGVQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSSRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            complement(5106..6005)
                     /gene="galU"
                     /locus_tag="VH957_001235"
     CDS             complement(5106..6005)
                     /gene="galU"
                     /locus_tag="VH957_001235"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEQ8559147.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(6038..7054)
                     /locus_tag="VH957_001236"
     CDS             complement(6038..7054)
                     /locus_tag="VH957_001236"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8559148.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            7352..7801
                     /locus_tag="VH957_001237"
     CDS             7352..7801
                     /locus_tag="VH957_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8559149.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            7794..9500
                     /locus_tag="VH957_001238"
     CDS             7794..9500
                     /locus_tag="VH957_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559150.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPFLFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLVQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            9503..11287
                     /locus_tag="VH957_001239"
     CDS             9503..11287
                     /locus_tag="VH957_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559151.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTMTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAVVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            11405..12172
                     /locus_tag="VH957_001240"
     CDS             11405..12172
                     /locus_tag="VH957_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEQ8559152.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWAKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            12282..12728
                     /locus_tag="VH957_001241"
     CDS             12282..12728
                     /locus_tag="VH957_001241"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEQ8559153.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            12809..14170
                     /gene="radA"
                     /locus_tag="VH957_001242"
     CDS             12809..14170
                     /gene="radA"
                     /locus_tag="VH957_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEQ8559154.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            14359..14856
                     /locus_tag="VH957_001243"
     CDS             14359..14856
                     /locus_tag="VH957_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEQ8559155.1"
                     /translation="MSYFEHFMAANQVYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVRKDMAKLRASSLIPDDVVINGAVYDVDTGKM
                     TQVME"
     gene            14987..15697
                     /locus_tag="VH957_001244"
     CDS             14987..15697
                     /locus_tag="VH957_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEQ8559156.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            15879..17324
                     /locus_tag="VH957_001245"
     CDS             15879..17324
                     /locus_tag="VH957_001245"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEQ8559157.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NEAGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
BASE COUNT         5360 a         3169 c         3767 g         5352 t
ORIGIN      
        1 tttgcttttt aagtattcaa atgattgcca tttttagata atgagagtaa gtaatgttaa
       61 gaagatagca tgagaaagta tttacaggtg attggggctt caattgcctt tgtgggtgtg
      121 gctttatgca ttgatcatat gcatgatggg gttattaccc gtgttgaaat gataaaatcc
      181 ttaaaataag ttattacggt aaagcggcct cagggccttt tttcatgata tttttaggaa
      241 atatgaaatc ctattttctc ttaaaaaaaa cactatgatg agaatatgct tgcattgaca
      301 catgttttat gtctgaaaaa acgaaaacct tttcaaaaaa cctagctttt tcacaggtga
      361 aaaccactaa aaaccattga aatattagat agaaaaggtt atcatactaa tgaaacttaa
      421 aattttaagg gagcgaaact catgtcacat attacatttg attattcaaa agtcctcgag
      481 tcatttgcgg gacaacatga aattgatttt ttacaaggcc aagtcacaga agctgacaag
      541 ttattgcgtg aaggaactgg accaggttca gatttcttgg gttggcttga tcttccagaa
      601 aactatgaca aagaggaatt tgcacgtatc ttgactgctg ctgaaaagat taaggcagac
      661 agcgaagttc ttgtggtgat cggtatcggt gggtcatacc ttggtgccaa agcagcgatt
      721 gattttttaa atcatcattt tgctaacttg caaactgcca aagagcgcaa agccccacaa
      781 attctttacg ctggaaactc tatttcatca acttacttag ctgaccttgt agagtacgtt
      841 caagacaaag aattctcagt aaacgtgatc tctaaatcag gtacaaccac tgagccagct
      901 attgcttttc gcgtgttcaa agaacttttg gttaaaaaat atggccaaga agaagctaac
      961 aaacgtatct acgctaccac agacaaagtt aagggtgctg ttaaggtaga agctgacgct
     1021 aacaactggg aaacatttgt ggtgccagat aatgttggtg gtcgtttctc agtcttgact
     1081 gctgttggtt tgcttccaat tgctgcatca ggtgcagata ttactgctct tatggaaggg
     1141 gcaaatgctg ctcgtaaaga cctttcttca gacaaaatct ctgaaaacat tgcttaccaa
     1201 tacgctgctg ttcgtaatgt gctttaccgt aaaggctaca tcactgaaat cttggctaac
     1261 tacgagccat ctcttcagta ctttggcgaa tggtggaaac aattagctgg tgaatcagaa
     1321 ggaaaagatc aaaaagggat ttacccaact tcagctaact tctcaacaga ccttcactca
     1381 cttggtcaat ttatccaaga aggttaccgt aacctctttg aaacagttat tcgtgttgat
     1441 aaccctcgta aaaatgttat cattcctgaa ttagcagaag acctagatgg tcttggttac
     1501 cttcaaggta aagacgttga ttttgttaat aagaaagcca cagatggtgt gcttcttgcc
     1561 cacacagatg gtggcgtgcc aaacatgttt gtcactcttc cagctcaaga cgagtttacc
     1621 cttggttaca ctatttactt ctttgagctt gccatcgctg tttcaggcta catgaatgct
     1681 gttaacccat ttgatcaacc aggtgttgaa gcttacaaac gtaatatgtt tgcgcttctt
     1741 ggaaaaccag gttttgaagc attatcagca gagcttaatg ctcgcctcta atcaacagat
     1801 agtcaaaaag acttcttcct tgtacaagag cttaaaagtt agccaagcaa tctaagaatt
     1861 ggggcggcac ttccatcatc aagtggatac aaggttaagt aaaagcgata ataaagtgcg
     1921 cttccagaac atgggagcgc actttattat gccaaatttc agataaaacc ttcaaaaaag
     1981 ggaagaagat cctacaagag gagttgaacc gctaaaacag ttccagttct gtttctaagc
     2041 aaatagcaat ggttaaaaag agagcttatc aaggttgcaa gtgacaacct taaagacccc
     2101 cctagactgt gaaagtatct aggagggact gtcaaaaaat taagaaggaa ctctccaaag
     2161 ttcttctaaa cgtttttggt agtggttctg gtgcaaggct aagatggttt tgattaaatc
     2221 ttcgcgctgc tgttggatac agtccaaact caaaccaaac aagcgggtct ctttgggaaa
     2281 aacaccgagt tcttttaaga aaggcaagag cttctgactg gtcacaacca gatctacagg
     2341 tttatcatag ggataaatat tatcagataa gatattgacc cgtgacagtt caactttgta
     2401 agaagggata gttgaggtga tgaaattagc tataacgtta ccaacagttt cttggctctc
     2461 aataacagta atattgattg gagcaataga gctttccaag atctgctcaa ggtataaaca
     2521 catcaagtgt aagtgaccag aactaatact gccttgacgg cctgtgtcat aaagccaatc
     2581 tttgataacg gtttcaagct tatctagtag tagcatgttg ccttgatatt gatcaaaata
     2641 ataaccatca aaggtaatta aagtttgtag attgtagaga gttcttttga aaaaaggaat
     2701 taagttaggg atatgctcat gaatatcgga atactttcca actagtgcct gaagacgatg
     2761 gattagtaaa tgataatcgg gatctttggt gattaaatgg taaagttgtt gtcgctgatg
     2821 acttgtccag tacccactca agaaggagtt atcagtcgtt aaataaatta aaaagagata
     2881 gtcaaaatca tcagacgaaa atgtgacacg agttcgaggt gctagctcat ccacggcaat
     2941 ggttttgata ttgtcaaaaa taggcaagga tttgagatgt tcaaaaagag ctaaatgagg
     3001 caaatgaaca ggatagcgat ggcgcttcca agtcaacatc aacagcacat caaaaaacaa
     3061 gaagcgtcta tctaaaaagg cagaaggttg taagtttttt tgtgctgcaa agataaaagc
     3121 atgaatcgtt tcaatgtctg caggttgtat atcatataat ataatgccgt actctttatg
     3181 taaaagagca atcaaatacc gtattttaag ttcatctccg ataacagtat tgtctacaat
     3241 atttaaacca atgtcttgta aataatgttt taatttatga ataagacgat aagcttttga
     3301 ctgggatatc ccttgttttc gtgtataaac agcgattgac ttgtgtttgg gattatctag
     3361 taataagaat gtcaacattt ttagagtatc tgataaggca aaaatatcat aaaaaaatgc
     3421 ttctcgctta tcatttaata cctcacaata aatacgagat ttaataagct caatacgtaa
     3481 gtacccttta aataaggcgt taaattgtcg aagatactgc tttattttta aagcagtcaa
     3541 agttgtttga gaacaagctg ctgccatcgt cagttctttt tctgtcaaca aaatagccag
     3601 taggattttc tggtcaataa tatcggattc caaataataa tctaacaatg taatttttct
     3661 ctccttaaat taaattgtat aatcctatat attgtagcga atctaccgta aaagtcaact
     3721 aaaatcaata ggattactaa tatagtcaca ataaagatca tcaaaaagca gcaaacttca
     3781 tcaatagatt gattgatgcg tgtttttagc ccataattga gagagctaag aacacgcggg
     3841 tgatatcata tttttgctgt tgacttttta aatttaaaaa cctaaccagc cggttaactg
     3901 gtcaggttta aacaagggag ggcacctaag aagataggtg cccaggagat ttatgaaaag
     3961 ggaaaacaag gggaaaacct attctcccaa cggtttaggt aaaccgcttt ttaggatgtt
     4021 ttcattctac gatagtaacc ttaaagtttt cttaaatgat tctttagaat gcctttattt
     4081 ttaatctttt ttgagagagc tagcttcttg tcagccttga acctttttcc taatttatgg
     4141 tatgataaga agataatgaa aaaagagatt ctcaaagaac tcttctagtc tttacgaact
     4201 atggatgtag acttaaaacg tcaaaatgat caagctttat tagtggatgt tgttagcaat
     4261 caagcttatc aacgggccaa tacgattgcc aaatcaaacg atttatgata ttgctgttta
     4321 ggaggtttat cttagatgac acggttatta aaacgatatc ctattactat tttcctttta
     4381 gggttaacag gcttaatttt tatagcaatg caagtggtat atggacattt agcaactggt
     4441 gttcaagcta tttatcaagt tggaggtatg tttggattac tagtaaaagc aatgccagat
     4501 cagttgtggc gattggtgac tccgatattt attcatatcg gttttggtca tttttttgtc
     4561 aatggattaa cactatattt tgttggtcaa atcgtcgaag acctctgggg ctcaagccgt
     4621 tttttattac tttatgtttt atcaggtgtt atgggcaatg cctttacttt ttggttgact
     4681 cctgaaacag tagctgcagg agcatcgacg tcgttatttg gactttttgc tgctattgta
     4741 gtattgagtt ttttgggtaa gaaccaagcg ttgaaagatt tgggcaagtc ataccaaacg
     4801 ttaattgtag tcaatttact gatgaatctt tttatgccaa acgtgagtat ggcaggccat
     4861 attggcggtg tcgtgggtgg tgcgttactg agtatagtat ttccaactaa gatgagagtg
     4921 ataacagtga agaaaaccaa gcgaatgttg gctttagtga gctatggtat tattttggtt
     4981 ggtgtgttag tgcttgggtt tttataaaaa taagtgagtg gttagcactg ttacttctca
     5041 gatggctagt aggatgaaac gactcaaaaa ccataaaaat aaggagggat tttccctcct
     5101 tatttttatg gttttgtttt ctctagtgct ttgcccagtt ggatgatgta ggctttcaag
     5161 tcatctttga cttgagggtg tttcagggca taatccaaag aagttttcat aaacccaaat
     5221 ttatcgccaa catcatagcg tttcccttta aactcacgag caaagacacg ctgtgtctta
     5281 ttgagggtat caatagcatc agtcagttga acttcattgc ctgcaccagg ttcttgtttt
     5341 tctaaaatac taaaaatttc tggtgtgagc aagtaacgtc caataattgc caaatcacta
     5401 ggtgcatctt gaggttgtgg tttttcaaca aaagtatcca cactatagag tccttttact
     5461 gcttttgctt gaggagcaat gataccgtag ttagagacat cctcgtgagg aaccctcatg
     5521 acggcaatag ttgcagcatg agtttcttca tagtcatcga tcaattgttt ggttaatggt
     5581 tttacatttg gatttgtaat atccatcaga tcatcaccta gcatgacaac aaaaggttca
     5641 ttgccaacaa aggtctttgc ttgaagaact gcgtctccta atcctcttgg atgactctgt
     5701 cgaataaagt gaagattaat agaagtggtc tcgtctacta actttagaag ttcgattttt
     5761 cctttagcct gtaaattata ttctaattca aaattagaat caaaatgatc ttctatggag
     5821 cgtttggatt ttccagtaac gataagaatt tcttcgatac ctgattttag agcttcttca
     5881 acgataaatt gaatagttgg tttatcaaca ataggtagca tctccttggc aagggccttg
     5941 gttgcaggta aaaaacgtgt gcctaaacct gctgcgggaa taatagcttt tctgactttg
     6001 gtcatcagca cctcctttta ttttagtgac gcatggctta atgccattca ttttcagaac
     6061 gaaattcatt tgacatcatg ccgaggatgc tttctttgat atcagcgccc tcgtagatgg
     6121 acttataaat agctgttgta attggcatgt aaactccgag gtcttgggca atttcatagg
     6181 ctaccttagt tgttgcgatg ccttcgataa ccatacccat gttgcgttca atatcttcta
     6241 atttttcacc acgtccaagg gcagctccag cccgccagtt acgtgaatgg acagaagtac
     6301 ctgttacaat tagatcacca acaccagata acccactgta ggttaacggg tcagcaccaa
     6361 gcttgacgcc tagacgggtg atttcagcta acccacgagt aattaccgct gctttggcat
     6421 tatctccata cccaagtcca tggagagctc ctgctccaac agcaataatg tttttgaggg
     6481 caccagctgt ttcaactccg atgacgtcgg tattggtata aagtcggaag tagtggttac
     6541 taaagaggga ctgaacatac tttgcagctt caatatcttt tgaggctgcc gtgatgagag
     6601 taatatcgcg aacgatagtt tcttcagcat gactaggacc tgatacaacg accacttcac
     6661 tacgaaaatg agctggaatt tcttcttcta ggatagttga taaacgttcg tgggtctctg
     6721 gttctagacc ttttgaggca tgcatgacca ctactttatg atctaaaatg gcggcaactt
     6781 gtctagcaac taatcgtgtc actttagttg gcacaacaaa aagcaccgca tcaacatctg
     6841 atagggcttg acctaaatca agagttgccg taatgttttt gtctaacaca atgtctttga
     6901 agtagtgtct attggtatgc ttggtattta tctcttcaat ttgatcagga atatttcccc
     6961 ataaacggac gtcatggcca ttgtcattaa gaacctgaga aagggcagtt ccccaagaac
     7021 caggtcctaa aatagctact ttttgttttg tcattctaaa ttctccttca agagctagtc
     7081 actctattat aacataacac cttgattagc tctattagaa aaggtatatg gtcttggcta
     7141 ataaggcgtt cccaagagag ctagctatat taataatgtt gtttaataag cttcatcagg
     7201 tgagctgttg tcatggcttt gccctgttct ttttagttat ttaagttcgg aaacttattt
     7261 ttaaaaataa agatatttta attgacaata gttatctaga gaactaaaat acttatcata
     7321 gaaactatta aagaaaataa ggagggaaga gatgtcacaa gtgataggtg atttacgtga
     7381 attgatacat caaatcgaac aaattagtga tgagattgca aaaaaatatg atgtagagca
     7441 tctagcaggt cctcaaggtt atgttcttgt ttttttagct aaacaccaaa atcaagaaat
     7501 atttgtcaaa gatattgaaa aacaacttcg tatctcaaag tcagttgcta gtcatttagt
     7561 gaaacgtatg gtcaaaaatg ggtttatcaa tgtgatgcct tcccaagtgg ataagcgtta
     7621 taagcaagta gtgttagcgc aggttggtag agataaattg cctttgttgc gggagtgtcg
     7681 taaggatatc gagcactatt ttttaaaaga aattacaaaa gaagagttgc tgacagcgaa
     7741 aaaagtaatt gaacagctca agcaaaatat gctaacttat aaaggagaca acgatgctta
     7801 aagacgcaat cttacgttat aaatggtatg ctttaggctc attttttatg gttattgggg
     7861 ttgttgcaag tagtctcttg caaccacatt atcttaaatc tgtgctaagc gctgttattc
     7921 aaaataatca agagaaaatt tatgaggttg ggaaaccatt acttattatt gcccttttag
     7981 ggttaatgtc tggagcgatt aatacggttt tagctgctaa aatagctcaa ggtgtatctg
     8041 ctgatatgag ggagaagacc tttcgaaaaa tccaagactt ttcatatgcc aatattgaag
     8101 cttttaatgc tggtaatctt gtggttaggc taactaatga tatcaatcaa atccaaagtt
     8161 tagtcatgat gatgtttcaa attctctttc gtttgccgtt cctttttatt ggcgcgttta
     8221 tcatggcagt tcagacattc cctcaattat ggtgggtcat tgttgtaatg gttatcttaa
     8281 ttgccctcat catgggtttg gtgatgcgtc aaatgggtcc tcgttttggt aaatttcaac
     8341 ggttaatgga taagattaat cgcatcgcta aggaaaatct ccgtggcgtt cgcgtggtta
     8401 aatcatttgt acaagaacaa caacaataca ctaaatttaa agaaacgtcc aatgatcttt
     8461 tggcgttaaa tttatctatt ggttatggtt tttcactaat gcagccggct ttaatgttgg
     8521 tgtcttattt ggcagtttat gtttctataa atgttgtttc gaccatggtc gaaacagatc
     8581 caacagtgat tgggaatatt gcctctttca tgacttatat gatgcaaatt atgttttcaa
     8641 ttattgtggt tggttccatg gggatgcaag ttagtcgtgc ttttgtttct atggctagaa
     8701 ttaggcaaat attgtctaca gaacctgcca tgacatttga aaatgaaaag gaagaaacca
     8761 tctcaggaag cattgtattt gacgatgtta gttttacata tcctaatgat gatgagccaa
     8821 ccttgaagca catttctttt gctattgaac ctgggcaaat ggtcggcatc gttggtgcaa
     8881 caggatctgg gaaatcaacg cttgtacagc tcatccctcg cttatttgat cctcaagatg
     8941 gccaaatttt gttaggagga aagccgatta aaaccctaag tcaaacaacc ctgcgccaat
     9001 cggtttccat cgtgttgcaa aaggctattc tcttttcagg aacgatagct gataaccttc
     9061 gccaaggctc agcaaaagct gatattgatg ctatgcaaaa agccgctcaa atcgcgcaag
     9121 caaaagaatt tattgatcgc atggatagcc gttatgagag ccaagttgaa gagcgaggta
     9181 gtaacttgtc tggcggacaa aagcaacgtc tgtctattgc acgtggtgtc attaatcatc
     9241 ccaaaatcct tatattagac gattccactt cagctcttga tgcaaaatct gaaaaacgcg
     9301 ttcaagaagc cttaagtcat aaattagaag gtacaactac agttattgtt gctcaaaaaa
     9361 tttcatcggt agttaaggca gataagatct tagtccttga ccaaggacag ttaattggag
     9421 aaggaacaca cgcagagttg gtggctaata atgcgattta tcgtgaaatt tatgagacac
     9481 aaaaaggaag ggaggagtag tgatgaaaac agcacgtttt ttctggtttt attttaaacg
     9541 ctatcgtttc tcgtttactg tcattgctgt tgccgttatc ttagcaactt atttacaagt
     9601 aaaagctcct gtcttcttag gggagtcctt gactgagttg ggaaaaatcg gtcaggctta
     9661 ttacgttgct aagatgagtg gtcagacaca ttttagccct gatttatcag cttttaatgc
     9721 cgtgatgttt aagcttttga tgacttattt ctttactgtt ttagctaatc taatatatag
     9781 tttcttactc acacgtgttg tctcacattc gaccaaccgc atgcgcaagg gcttgtttgg
     9841 taaattagaa cgtttaaccg tcgccttttt tgaccgccat aaagatgggg agattctttc
     9901 tcgtttcacg agtgatttgg ataatattca aaactcgctg aaccaatcct tggttcaagt
     9961 ggtgactaat attgcccttt acatcggcct ggtctggatg atgtttaggc aagatagccg
    10021 tttagctttg ttaaccatcg catcaacccc agttgctctc atttttttag tgattaacat
    10081 ccgtttggca agaaaataca ccaatatcca acagcaagaa gtcagtgctt taaatgcttt
    10141 tatggatgaa accatttcag gacaaaaggc tattattgta caaggtgtcc aagaagatac
    10201 gatgacagcc tttttaaagc ataatgaaag ggttcgacaa gccaccttca aacgccgtct
    10261 gttctcagga caattatttc cagtcatgaa tggaatgagc cttattaaca cggctgtcgt
    10321 gatttttgtc ggttcaacaa ttgtcctcag tgacaaatct atgccagcag cggcagcgct
    10381 tggtttagtg gttacttttg tacaatattc ccagcaatat taccaaccca tgatgcaaat
    10441 cgcgtctagt tggggagaat tgcagctggc ctttaccggt gctcaccgta ttcaagaaat
    10501 gtttgatgaa accgaagaag ttcgtccaca aaatgcacca gcgttcacca gcttaaaaga
    10561 agcagtggcg attaaccacg tcgattttgg gtatcttcct gggcaaaaag ttttatcaga
    10621 tgtgtcaatc gttgcaccca agggcaaaat gattgccgtg gttggaccga caggttctgg
    10681 aaagaccact attatgaact tgattaaccg tttctacgat gtggatgcag gttcgattac
    10741 ctttgatggc cgtgatattc gtgactacga tttggatagt cttcgtcaaa aggtagggat
    10801 tgtgttgcaa gagtcagttc ttttttcagg aaccattacg gataatattc gttttggtga
    10861 tcagaccatt agtcaagaca tggttgaaac tgctgcgcgt gcgacccata ttcatgactt
    10921 tatcatgtcc ttaccaaaag ggtacaatac ctatgtctca gatgatgaca atgtcttttc
    10981 aacaggtcaa aagcagttga tttctattgc taggacgcta ctgacggacc ctgaagtgtt
    11041 gattttggat gaggccactt caaatgttga tacggttacc gaaagtaaaa ttcaacgggc
    11101 catggaagct atcgtggcag gtcgaaccag ctttgtcatt gctcaccgcc tcaaaaccat
    11161 tttaaatgcc gatcacatta ttgtgttgaa agatggcaag gtcattgagc aaggaaatca
    11221 tcatgagcta ttgcatcaaa aaggctttta tgccgaattg tatcacaatc aatttgtctt
    11281 tgaatagatg gcatcagctc cgcttcttag cggagttttt tggtgaacaa taaagcagtc
    11341 aagctttctt tcctgatatg gtataatagc aagcaagaga aaaaacaatt agaaagtagc
    11401 cacaatgatt gatttacaag agattctcgc taacatgaat cccaatcaaa agataaatta
    11461 tgacagggtc atgcaacaga tggccaaggt ttgggctaag gaatccgtgc gtcccagtat
    11521 tttaatgcat gtctgctgcg ccccatgctc cacttacacc ctagaatacc tgacgcagtt
    11581 tgctgacatt acggtttact ttgccaattc taatattcac cctaaggacg aataccatcg
    11641 cagagcctat gtgacacaac agtttgtctc cgagttcaac gctaaaacag gcaacaccgt
    11701 gcagtttctc gaagcggact atgtccccaa tgagtacgtt cgacaagtgc gaggtttaga
    11761 agaagaacca gaaggtgggg accgttgccg tgtctgtttt gattaccgac tagacaagac
    11821 cgctcaaaaa gcagtggaac taggttttga ctactttgcc agtgccctaa ccatcagtcc
    11881 tcataaaaat tcgcaaacca ttaatgatgt gggcatcgat gtgcaaaagg tttacaccac
    11941 caaatacctg ccaagtgatt tcaagaaaaa caacggttat cgcagatccg ttgaaatgtg
    12001 tgaggagtat gatatttacc gtcaatgcta ttgtggctgt gtctatgctg ccaaaatgca
    12061 aggtattgac ttggttcaag tgaaaaaaga tgccaaagct tttatggcag acaaggattt
    12121 ggataatgat ttcacccaca tccgctttag ttatcgtggg gatgagatgt gatggcatga
    12181 ttaaaagtgg tccgtttaaa gttgaccgct tttttgctat tcttttacga atagtctata
    12241 ataagaggac atgattgact tgaaaggata tacctatcat aatgacaaaa attcgtggtt
    12301 tcgagcttgt ttcaagcttt actaatcctg atttactacc aaaacgtgag acgactcatg
    12361 cagctggtta tgacctgtct gttgctgagg ctgtgaccat tgccccaggg gagattaagt
    12421 tggtaccaac aggggttaaa gcctacatgc aagatggcga ggtgctttac ctctatgatc
    12481 gttcgtcaaa tccacgaaaa aaagggatta tcctgattaa ttcagtaggt gtgattgatg
    12541 cagattatta tggcaatgag gctaatgaag gacatatttt tgcacaaatg caaaacatta
    12601 cagatcaccc tgtgacatta gctgtgggtg agaggatcgt tcagggggtt tttatgcctt
    12661 ttttaattgc tgatggtgac caagccagag gtgaacgaac aggtggtttt ggttcgacag
    12721 ggcagtaaag cgatttaaca aaaatgctta tgacagcaga cctattcttt aagagtgggt
    12781 ttgtcttgtc taggggaggg agattactat ggcaaagaaa aaagcaacct ttatctgtca
    12841 ggagtgtggc taccagtcgc caaaatattt agggcgctgt ccaaattgct cggcctggtc
    12901 ttcttttgtg gaagaagtag aggtcaaaga agtcaaaaat gcccgtgtta gtctagctgg
    12961 agaaaagtcc agaccggtta aactaaaaga tgtggataat attagttatc acagaacaca
    13021 gactgacatg tctgaattta atagagttct tggagggggt gtggttcctg gaagcttgat
    13081 tttaattggt ggtgatccgg gtattggaaa atccacctta ctcttgcagg tatccacgca
    13141 gctcgctaat aagggaacgg ttctctatgt gtctggggaa gaatcagcag agcagattaa
    13201 actgcggagt gagcgtctgg gtgatattga caatgaattt tacctctatg ccgaaaccaa
    13261 tatgcaagct attcgcacag aaattgaaaa tattaaacca gattttttaa ttattgactc
    13321 cattcagacc atcatgagcc ctgatattac aggtgttcaa ggatcagtca gtcaggtgag
    13381 agaagtcact gcagaattga tgcagcttgc aaagacgaac aatattgcaa cctttattgt
    13441 gggtcatgtc accaaggaag gaaccttggc tgggcctcgt atgttagaac acatggtgga
    13501 taccgttctc tactttgaag gggaaaggca tcacaccttt cgcattcttc gggctgtgaa
    13561 aaaccgcttt ggctccacta acgagatcgg catctttgaa atgcagtctg gcggcttggt
    13621 agaggtctta aatcctagtc aagtcttttt agaggaacgc ttagatgggg caacaggatc
    13681 ggctgtcgtt gtaacgatgg aaggaagtcg tcctatctta gcagaggtgc aatctttagt
    13741 gacaccaacc gtttttggca atgccagacg aaccactacg ggacttgatt tcaatcgcgt
    13801 aagcctaata atggcagttt tagaaaagcg ctgtggttta ctcttacaaa atcaagatgc
    13861 ctacctcaag tcggctggtg gtgtcaaact agacgaacct gccattgatt tggcagtcgc
    13921 tgtggctatc gcatccagtt ataaggaaaa accaaccagc cctcaagaag ctttcttagg
    13981 cgagatcggg ttaacaggtg agattcggcg agtgacccgt attgagcaac ggattaatga
    14041 agcagcaaag cttggattta ccaaggtcta tgctcctaaa aatgccttgc aaggcattga
    14101 tatccctcaa ggtattgagg ttgtcggagt gactacggtt ggtcaggttt taaaggcagt
    14161 ttttagctag aggatcagaa actaagagca aatgaggagg aaatttgtca agaaagtatc
    14221 ccaatcattt gttttttaaa cttttcgaac gataccgacc gtctaagagg ttaatccagc
    14281 tattttccat aaaagatgtt aagataagac aaactaacag caaaaatagc tctgctgttt
    14341 ctcaaaagga gtttattgat gtcttatttt gaacatttta tggctgccaa tcaggtttat
    14401 gtggccttgc atgggacagc tcatttgccc ttaaaaccca agactaaagt agcgattgtg
    14461 acttgtatgg attcacggct acatgtggcc caagctctgg ggctggctct aggagatgct
    14521 catattttaa ggaatgctgg cggacgtgtc accgaagaca tgattcggtc gctggttatt
    14581 tctcagcagc aaatgggaac gcgagagatt gtggttctcc accatacaga ttgtggcgcg
    14641 cagactttta ctaatgaagg ctttgccaag catattcatg agcacttagg tgtggatgtt
    14701 tcagggcaag atttccttcc cttccaagat gtggaagaca gtgtccgcaa ggatatggct
    14761 aagctaagag cctcctctct tatccctgat gatgtcgtta ttaacggtgc cgtctacgat
    14821 gtggatactg gaaagatgac acaagtaatg gaatagttag tagccaagtt gtagagctga
    14881 attcagctct tttttatttt taaaaattat tgaaaatatt agacaaagaa atagggaagc
    14941 gttataataa ttgtatcaag ttattcatac aaacaaggag agtaagatgg tcgacaatag
    15001 aatgagattt acgattgatc aaaacatgca atttccacta gttgagattg atctggaaca
    15061 tgggggatca gtttacttac aacaaggaag tatggtttat catactgaga atgtaacctt
    15121 gaataccaaa ttgaatggta agggatctgg tttaggaaaa ttagttggag ccatcggccg
    15181 ttccatggtt tctggtgaat caatgttcat tacacaagct atgtcaaatg gagatggtaa
    15241 attagcatta gcacccaata caccaggaca gattgttgct ttagaactag gtgaaaaaca
    15301 atatcgtcta aatgatggtg cctttctagc cctagatggt tcagcacagt acaaaatgga
    15361 acgtcaaaat attggaaaag cactttttgg tggtcaaggc ggactttttg tcatgacaac
    15421 tgaaggcctt ggtaccttac ttgctaactc gtttggatct atcaagaaaa tcacacttga
    15481 tggtggcaca atgactattg ataatgccca tgttgtagca tggagcagag aacttgatta
    15541 tgatattcat ttagaaaatg gctttatgca gtcaattggt acaggtgaag gagttgttaa
    15601 tacctttaga ggtcatggtg agatttatat ccaaagtctt aaccttgagc aatttgctgg
    15661 gactcttaaa cgttatctac caactagttc aaattagtca aaataacata aaatcagctt
    15721 tttggggctg atttttttcg cctaagcaag taaaatatgc tataataaga aagattttag
    15781 aagaagtctg aaaaggtctt ggcaagctca aatcatcatt tgttgcttgt ttttcgtgcc
    15841 acagatttct gagtgatata tgtaacagga gaagaagcat gtctaaacca attcgtgtgc
    15901 gttatgcacc aagtccaaca gggcttttac atatcgggaa tgcccgcaca gccctattta
    15961 attaccttta tgcccgtcgt cacggaggta cttttatcat tcgtattgaa gatactgacc
    16021 gtaaacgtca tgttgaagat ggtgaacgtt ctcaacttga aaacctaaaa tggttaggaa
    16081 tggattggga tgaaagccca gaaacgcatg aaaattaccg ccagtctgaa cgtctagcac
    16141 tttatcaaca atatattgat caattgttag ctgaaggaaa agcctataag tcttacgtga
    16201 ctgaggaaga attggcagca gagcgtgaac gccaagaagc agctggcgaa acgcctcgct
    16261 atatcaatga atttattggt atgtcagctg acgaaaaagc taagtacatt gctgagcgtg
    16321 aagcagcagg tatcgttcca acagtccgtc ttgctgttaa tgaagctggt atttacaaat
    16381 ggacggacat ggttaaaggc gatattgagt ttgaaggtgg caatatcggt ggtgactggg
    16441 ttattcagaa aaaagatggt tacccaactt acaactttgc ggttgttgta gatgaccatg
    16501 acatgcaaat ttcacatgtt atccgtgggg atgaccatat agccaatacg ccaaaacaat
    16561 tgatggtcta tgaagctctt ggctgggaag cgccagagtt tggtcatatg actcttatca
    16621 tcaattctga aacgggtaaa aaattatcaa aacgcgacac caataccctc caattcattg
    16681 aagattaccg caaaaaaggt tatatgcctg aagctgtctt taacttcatc gcccttcttg
    16741 gctggaatcc tggcggagaa gaggaaatct tctctcgtga gcaactgatt gccctttttg
    16801 atgaaaatcg ccttagcaag tcgccagctg cctttgacca gaagaaaatg gattggatga
    16861 gcaatgagta tcttaaacat gcggattttg aaacagttta tgccctctgc aaacctttcc
    16921 ttgaagaggc aggccgtttg acagaaaaag ctgagaagct agtagaatta tacaaacctc
    16981 aattaaaatc tgcagatgag attattccat tgactgacct tttcttttct gatttccctg
    17041 aattaacaga agccgaaaaa gaagtgatgg caggtgaaac agtttcgaca gtcttgcaag
    17101 ctttcaaggc taagttggaa gctatgtcag atgaagactt caaaccagaa aatattttcc
    17161 cacaaattaa ggctgttcaa aaagaaacag gaatcaaagg gaaaaacctc tttatgccta
    17221 ttcgtattgc agtatctggt gaaatgcatg gcccagaatt accaaatacg atttatttat
    17281 tgggacgtga taaatccatt gagcacatca aaaacatgct ataaggctgt atcgttcacc
    17341 tttattttta aacgctttaa ggagttaaaa agtcacgaca acgaaagatt gaagattaag
    17401 ttcttcagtc ttttttatcg ttatctgagc ttgctacctt ggtaaagtaa aaaatagtat
    17461 agtttatttc tattttggag attggatttg aaagagaggt ggtgagatgc ttacgtgata
    17521 atgacagcaa acggtgaggt tttgattagt gtgatttaaa gaaatggttt ttatgaatca
    17581 attagtgtac aatatttttt tggtatatgc tgaaagagac tagtttagta ttcacttagc
    17641 taatcaat
//
LOCUS       DAUGOH010000031        17577 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUGOH010000031 DAUGOH010000000
VERSION     DAUGOH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17577
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.031"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            35..739
                     /locus_tag="VH957_001246"
     CDS             35..739
                     /locus_tag="VH957_001246"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEQ8559158.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENMIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVATHYIEQISKNEQLNKKVDIIPLEVVLRNVTAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKCWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            863..4588
                     /locus_tag="VH957_001247"
     CDS             863..4588
                     /locus_tag="VH957_001247"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEQ8559159.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIEALPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFENYKADDFTAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHSGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRLSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGEIIVDLERRFLDTNGVRVVVDVKVVDKDLTV
                     PEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKDNFSQFEAIQAQHKIT
                     AASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            4749..6203
                     /locus_tag="VH957_001248"
     CDS             4749..6203
                     /locus_tag="VH957_001248"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEQ8559160.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNPNFIGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDSGIQCNRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     HLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAADEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6231..7253
                     /locus_tag="VH957_001249"
     CDS             6231..7253
                     /locus_tag="VH957_001249"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEQ8559161.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGFASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVRAALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     ASVVIK"
     gene            7421..7975
                     /gene="purN"
                     /locus_tag="VH957_001250"
     CDS             7421..7975
                     /gene="purN"
                     /locus_tag="VH957_001250"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEQ8559162.1"
                     /translation="MKIAVFASGNGSNFQVIAEHFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYERRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8159..9706
                     /gene="purH"
                     /locus_tag="VH957_001251"
     CDS             8159..9706
                     /gene="purH"
                     /locus_tag="VH957_001251"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEQ8559163.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLDWDIISTGGTKVALDDAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDVDAAIRIIRDFKDRPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKIHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEAIALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9764..10888)
                     /locus_tag="VH957_001252"
     CDS             complement(9764..10888)
                     /locus_tag="VH957_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ8559164.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFIVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            11142..12407
                     /gene="purD"
                     /locus_tag="VH957_001253"
     CDS             11142..12407
                     /gene="purD"
                     /locus_tag="VH957_001253"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEQ8559165.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVKPVLEGMIAEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKIDGDIITYYAGAKFAENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDPTGLFYRNDIGSKAIRE"
     gene            12685..13176
                     /gene="purE"
                     /locus_tag="VH957_001254"
     CDS             12685..13176
                     /gene="purE"
                     /locus_tag="VH957_001254"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEQ8559166.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            13163..14236
                     /gene="purK"
                     /locus_tag="VH957_001255"
     CDS             13163..14236
                     /gene="purK"
                     /locus_tag="VH957_001255"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEQ8559167.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IVEKDFLANKAGVTVAPYKVVTSSLDLGGLDLTKTYVLKTATGGYDGHGQKIIRSAED
                     LPEVQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHRNNILSKTIVPA
                     RISDQLADKAKKTAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVTENPSAHLHMYGKLE
                     AKHNRKMGHVTLFAEDADEVEEF"
     gene            14238..15656
                     /locus_tag="VH957_001256"
     CDS             14238..15656
                     /locus_tag="VH957_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559168.1"
                     /translation="MYLKYIFKIKDRNLVSDYESLVRNLTINLQKLVIKDRTALIGDK
                     QLPITIYYRGENEKFPTGIVKVESDSVEGLELFDKTIKEIVGNESRFGKFTCIYDGIS
                     TYYSTEIYSELHEIERRTQEFLREAFFLSDKSGELKEYQATIKKMDSSDFSFSKLINE
                     IFKASDITDTFIDHVRACVEFGTVPNGDLLPKSFWDSLDNSLLDDKEQGLEINNLLNE
                     IRSTRNTIAHCKEFKKKDYINCIEQVKKLKQALDKIIASIESTDISKMSREVSRINNS
                     LQADNDYIKQKYFIEYDIFEKDILARTGLLEIDWENVSDDIEPLKIHRNFYESISEKT
                     DSEVIEEIKNLEDINFTDEKGNDLDDLTIIVPAQDEGFKRVFLGQREWYDIRIGKSKR
                     NRIKYIAGYEVAPESGVKYWAEVDKIVPSDNYVGYWKVIFKGEVKEYSEYKKLGNTWP
                     PQNSRYVSKKALDEAKYLSDVF"
     gene            15676..16968
                     /gene="purB"
                     /locus_tag="VH957_001257"
     CDS             15676..16968
                     /gene="purB"
                     /locus_tag="VH957_001257"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEQ8559169.1"
                     /translation="MISRYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEQYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDIKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
     gene            17098..>17577
                     /gene="rgg4"
                     /locus_tag="VH957_001258"
     CDS             17098..>17577
                     /gene="rgg4"
                     /locus_tag="VH957_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEQ8559170.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     "
BASE COUNT         5198 a         3339 c         4077 g         4963 t
ORIGIN      
        1 ttaaatgaaa acagaaagaa aggcgaataa tcaagtgact aaccagctta tttataaagg
       61 aaaagcgaaa gatatttata gtacaaaaga tgaaaatatg attagaacgg tctataaaga
      121 ccaagctact atgttgaatg gagctcgtaa ggagactatt gatggcaagg gagcactaaa
      181 taatcagatt tcatctctta tttttgagaa attaaataag gctggtgtgg cgacacatta
      241 tattgagcaa atttcaaaaa acgaacaatt gaataaaaaa gttgatatta ttccgcttga
      301 ggtggtgtta cggaatgtga cagcaggctc attttcaaaa cgttttggag tggaagaagg
      361 acgtgttctt gaaacgccaa ttgtggaatt ttactacaaa aatgatgatc tgaatgatcc
      421 ttttatcaat gatgagcatg tgaagttttt gggtattgtt aatgatgagg agattgctta
      481 tctgaaagga gagactcgcc gtattaatga actcttgaaa tgttggtttg ctcagattgg
      541 gcttaacttg attgacttca agttggagtt cggatttgat caagaaggta caattatctt
      601 agcagatgaa ttttcgcctg ataactgtcg cctatgggat aagaatggta accatatgga
      661 caaggatgtt tttagaagag accttggcaa cctgacggat gtctatcaag ttgtacttga
      721 gaagttgata gcattgtaac tagaagagga aggaattgaa tccgttcggg aaactccgaa
      781 aaaaagatgg aacttactga aatctcaatt tcagatgtcc tcctattttc cagtcgctcc
      841 cttgtcggac ttggtatctt atatgaataa acgtattttt gttgagaaaa aggctgactt
      901 tggtattaaa tcggctagtc ttgtgaaaga gttgacgcat aatctacaac tgacctcttt
      961 gaaggctttg cgtattgtgc aggtctatga tgtcttcaat ttggctgagg atttgctggc
     1021 gcgtgctgag aagcatattt tctctgagca ggtgacagac tgtcttttga cggaaactga
     1081 aatcactgcg gagcttgata aggttgcctt ctttgccatt gaggcgcttc ctggtcaatt
     1141 tgaccaacgt gctgctagtt cgcaagaagc tttgctatta tttggaagcg acagtcaggt
     1201 taaggtcaat acagcccagc tttacttggt caataaggat attacagaag cagagcttga
     1261 agccgttaag aactatcttt tgaaccctgt tgattcgcgt ttcaaggaca ttactttgcc
     1321 gcttgaagag caggctttct ctgtgtctga taagacgatc cctaatcttg atttctttga
     1381 aaattataaa gctgacgatt ttacggccta taaggcagag cagggcttgg ctatggaggt
     1441 cgatgacctt ctcttcatcc aagattattt caaatcaatc ggacgtgtgc caactgagac
     1501 tgagttgaaa gttttggata cttactggtc agaccactgc cgtcacacaa cctttgaaac
     1561 tgaattgaag aacattgatt tttcagcttc taaattccaa aaacaattgc agacaactta
     1621 tgacaaatat atcgccatgc gtgatgagct tggtcgttct gaaaagccac aaacacttat
     1681 ggatatggcg actatttttg gtcgttatga gcgtgccaac ggtcgtctgg acgatatgga
     1741 agtctcagat gaaatcaatg cctgctcagt tgagattgaa gtagatgttg atggtgtgaa
     1801 agagccttgg ctcctcatgt ttaagaacga gactcacaat cacccaacag aaattgagcc
     1861 attcggtgga gcggcgactt gtatcggtgg tgctattcgt gacccattgt cagggcgttc
     1921 atacgtttat caggctatgc gtatttcagg cgcaggcgat atcacgactc cgattgcgga
     1981 aacacgtgct ggtaaattgc cacaacaagt tatttctaaa actgcggcgc acggctattc
     2041 ttcatatggt aaccaaattg ggcttgcgac aacttatgtg cgtgagtact tccactctgg
     2101 ctttgtagcc aaacgtatgg agcttggagc tgtggttggt gctgcaccta aggaaaatgt
     2161 ggttcgtgaa aaaccagaag caggtgatgt ggtcatcttg ctcggtggta aaacaggtcg
     2221 tgatggtgtc ggcggtgcga caggttcatc taaggttcaa acggttgaat ctgtggaaac
     2281 agcaggagca gaggtacaaa aagggaatgc catcgaagag cgtaagattc aacgtctttt
     2341 ccgtgatggc aatgtcactc gtctgatcaa gaaatcaaat gacttcggtg caggtggtgt
     2401 ctgtgttgcc atcggtgaat tggctgacgg tcttgaaatc gatttggaca aggtgcctct
     2461 taaataccaa ggtcttaatg gtactgaaat tgcaatctca gaatctcaag agcgtatgtc
     2521 agtcgttgtt cgtctaagtg atgtggatgc cttcatcgca gcctgcaaca aggaaaatat
     2581 cgatgcagtc gttgttgcga ccgttactga aaaaccaaat cttgtcatga cttggaatgg
     2641 cgaaatcatc gttgatttgg aacgccgttt ccttgatacc aatggtgtcc gtgtcgttgt
     2701 tgatgttaaa gtcgttgaca aggacttgac agttccagaa gcacgtacaa catcagcaga
     2761 gacacttgaa gcagatacgc ttaaggtctt gtctgacctc aaccacgcta gtcaaaaagg
     2821 tctccaaacc atctttgact catctgttgg tcgttcaacc gttaaccacc caatcggtgg
     2881 tcgttaccaa atcacaccga cagaaagttc tgttcaaaaa ttgccagttc aacatggtgt
     2941 gacaacaact gcatctgtta tggctcaagg ttacaatcct tatattgcag agtggtcacc
     3001 ttatcacggt gctgcctatg ctgtcattga agcgacagct cgcttggtag caacgggtgc
     3061 tgactggtct cgtgcacgtt tctcttacca agagtacttt gagcgtatgg ataaacaggc
     3121 agagcgtttt ggtcagccag tatcagctct tcttggttct attgaggctc agattcaact
     3181 tggtttgcca tcaatcggcg gtaaggactc tatgtctggt actttcgaag acttgacagt
     3241 accaccaacc ttggtagctt tcggcgtgac aacagcggac agccgcaagg ttctctctcc
     3301 tgagtttaaa gcggctggcg aaaacattta ctatatccca ggtcaagcta tttcagaaga
     3361 tattgatttt gaccttatca aggataactt tagccagttt gaagctattc aagctcaaca
     3421 taagattaca gctgcctcag ccgctaaata cggtggtgtc ctagaaagtc ttgctctcat
     3481 gacttttggt aaccgtatcg gtgcttctgt tgaaattgca gagcttgaca gcagcttgac
     3541 agctcaactc ggaggttttg tctttacatc agctgaggaa attgctgacg cggtgaaaat
     3601 cggtcaaact caggcagact ttacagtcac agtcaatgga aatgaccttg ctggcgctag
     3661 ccttctagca gccttcgaag gcaaattgga agaggtttac ccaacagaat ttgaacagac
     3721 agatgttctt gaagaagttc ctgctgtggt atcagatact gttatcaagg ctaaggaaac
     3781 aattgaaaaa ccagtggttt acattccagt cttccctggt accaactcag aatacgattc
     3841 agctaaggcc tttgaacagg ttggagctag tgtcaacttg gtaccatttg taaccttgaa
     3901 tgaggttgct attgctgagt cagttgacac tatggttgct aatattgcta aggcaaatat
     3961 catcttcttt gctggaggtt tctcagcagc ggatgaacca gatgggtctg ctaagtttat
     4021 cgtcaatatc ttgcttaacg agaaggtccg cgcagctatt gacagcttca tcgaaaaagg
     4081 tggccttatc atcggtatct gtaatggttt ccaagccctt gttaaatcag gtcttcttcc
     4141 atacggaaac ttcgaggaag ctggtgagac aagtccaact ctcttctata acgatgctaa
     4201 tcagcatgtt gccaagatgg ttgagactcg tatcgcaaat accaactcac cttggttggc
     4261 aggagttgag gtcggcgata ttcatgccat tccagtttca catggtgaag gtaaatttgt
     4321 tgtcagcgct tctgaatttg cagagctaag agacaatggt caaatctgga gccaatatgt
     4381 ggactttgac ggacaaccat ctatggattc taaatacaat ccaaacggct ctgtcaatgc
     4441 catcgaaggg attaccagca agaatggtca aatcatcggt aagatgggac actcagaacg
     4501 ctgggaagac ggactcttcc aaaatatccc tggtaacaaa gaccaaaccc tctttgcaag
     4561 tgctgtaaaa tactttacag ggaagtaaaa aggttcagtg aaccttttta gccctcgcct
     4621 tgaattagtg aagggcgagg ttagaaagaa tctcgcttaa tttttgagaa atagtaaaca
     4681 cgggcgataa gttgtgcgaa aaactttcta ttttcgcttt acttgacagc ctttgtatcg
     4741 aggtaaaaat gacatacgaa gtaaaatctc taaatgaaga atgtggagtc tttggtatct
     4801 ggggacatcc tcaggcagct caagtcactt actttgggct tcatagcctt caacatcgcg
     4861 gtcaagaagg agctggtatt gtttcaaatg acaatgggaa actctatggt tatcgaaatg
     4921 ttgggctcct ttctgaagtt tttaagaatc aatctgaatt agataattta actgggaatg
     4981 cggctattgg acatgttcgg tatgctactg caggttctgc agatattcgc aatattcagc
     5041 cttttcttta taaatttcat gacgggcaat ttgctttatg ccataatggt aatttgacaa
     5101 atgctatttc cttaaggaaa gaattagaaa agcaaggtgc aattttcaat gcctcctcag
     5161 atactgaaat tttaatgcat ttgattcgtc gaagccataa cccaaatttc ataggaaagg
     5221 taaaagaagc tctaaataca gtaaagggtg gctttgccta tctactgatg acagaaaata
     5281 aactcattgc tgctcttgac cctaatgcct ttcgtccttt gtcaattgga caaatgcaaa
     5341 atggtgcctg ggttatttcc agtgagacct gtgcttttga ggtggtaggc gcaaaatggg
     5401 ttagagatgt tgaacctggc gaagttattc ttatagacga tagtggtatt caatgtaatc
     5461 gttatactga tgaaacgcaa ctggcaattt gttcgatgga atatgtctat tttgcaaggc
     5521 cggattcaac tatacatggt gttaatgttc atacggctcg aaaaaatatg ggaaagcatc
     5581 ttgcacaaga atttaaacag gatgctgata ttgtaattgg tgtcccaaat tcgtccttat
     5641 cggctgctat gggctttgct gaagaatccg gattaccaaa tgagatgggt cttgtaaaaa
     5701 atcagtatac gcagcgaacc tttattcaac cgacacaaga attaagggaa caaggtgttc
     5761 gaatgaaact atcagcggta tctggtgttg tcaaaggaaa gcgcgttgtt atgattgatg
     5821 actcaattgt aagaggaacg acttctagaa ggattgtcgg attattaaga gaagcaggag
     5881 ctagtgaagt acatgttgct atagctagtc cagaattaaa gtatccttgt ttttatggta
     5941 ttgatattca aacaagacga gaattaattt cagcaaatca cgctgctgac gaagtgtgtg
     6001 atattattgg cgcagatagt ctgacctatc tctcactaga tgggttgatt gaatcaattg
     6061 gactcgaaac aaaagcacca aatggtggtt tatgcgtagc ttactttgat ggacattatc
     6121 caacaccgct ttatgattat gaagaagaat acctcagaag tttagaagaa aaaacaagtt
     6181 tttatattca aaaagtgaaa taagctctgc taattatata aggagaaaac atgtctgaaa
     6241 aaaatgctta tgcaaaatct ggtgttgatg ttgaagctgg ttatgaagtg gttgaaagaa
     6301 taaaaaaaca cgttgctcgt acagaacgtg cgggagtcat gggagctcta ggtggctttg
     6361 gtgggatgtt tgacttgagt aaaacaggag ttagagagcc tgttttggtc tcagggacag
     6421 acggtgttgg cacaaaactc atgcttgcta tcaagtacga caagcacgac acaatcggtc
     6481 aagactgtgt tgccatgtgt gtcaatgata ttattgcagc aggtgctgag cccctttact
     6541 tccttgacta cgtagcgaca ggaaaaaata atccagtcaa atttgaagaa gttgtttctg
     6601 gcgttgcaga aggttgtgtt caagcaggag cagcactcat tggaggtgag accgctgaaa
     6661 tgcctgggat gtatggcgaa gatgattatg accttgctgg ctttgctgtt ggtgtggctg
     6721 aaaaatctca gctcatcgac ggttcaaaag taaaggaagg cgatattctt ttgggatttg
     6781 cttcaagtgg tatccattca aacggttatt ctttggtacg tcgtgtcttt gctgactata
     6841 ctggtaaaga gctgcttcca gaacttgaag gaaaacaact taaggatgtc cttcttgagc
     6901 caactcgtat ttatgttaga gcagctctgc cattaatcaa ggaagaacta gtcaacggta
     6961 tcggccacat cacaggtggt ggctttatcg agaatgttcc tcgtatgttt gcagatgatt
     7021 tggctgcgga aatcgatgag gacaaggtgc cagtgcttcc gattttcaag gcgcttgaaa
     7081 aatatggtga catcaagcac gaagaaatgt ttgaaatctt caatatgggt gtcggtctta
     7141 tgctagctgt tagtcctgaa aatgttaacc gcgtcaaaga gctcttggat gaaccagttt
     7201 atgaaattgg tcgtatcatc aagaaagcag acgctagtgt ggtgattaaa taagtcacta
     7261 aattttataa gaaaggagtg tttagttagt ttgcctaact gaacacggga ttaaatttct
     7321 aggaaaaaag ataaaatgac ttagacgcaa gcgtcgttgt tcgttttcct atttttctac
     7381 gaaatttttc ggcaagccga atcatccctt tgtatcgaat atgaaaatcg ctgtttttgc
     7441 ttctggtaat ggttccaact ttcaggtcat agcagagcac tttccagtta gttttgtctt
     7501 ttcagatcat cgtgatgcct atgttttaga gcgtgctcag aatttagcca ttccaagctt
     7561 cgcttttgaa ctcaaggagt ttgagaataa ggcggcttac gagcaagcca tcgttgattt
     7621 gttggacaaa cacgagattg acttagtctg tctggcgggc tatatgaaga ttgttggaga
     7681 aaccttactc ttggcctatg agaggcgtat tatcaatatt cacccagcct acctgcctga
     7741 atttccaggt gcccacggta tcgaggatgc ttgggaagct ggtgttgacc agtctggcgt
     7801 gaccatccac tgggttgact ctggtgtgga taccggtcag gtcatccaac aagtgcgcgt
     7861 gccacgccta gcagacgata gcctagaaag ctttgaaacc cgtatccatg aaaccgaata
     7921 tcaactctac ccagctgtct tagatagctt gggagtggag aggaaagtaa tctagccttt
     7981 atcttaaaat tttaggtaaa gttaggaaag atagtaaaga agaattaacg ttccaaaaag
     8041 aaaggaattg aacccgtctg gaaggcacag aaaaaagata aacatctcct aggcgcaagc
     8101 gtcttcgtcg agtttcctat ttttccttgg ccttctagtc ggacttggta tcttaaatat
     8161 gactaaacgt gctttaatct cagtgtctga caagtcagga attgttgact ttgcaaaaga
     8221 attgaaaaac ttggattggg atattatctc aactggtggg actaaggttg cccttgacga
     8281 tgctggtgtt gagaccattg ccatcgacga tgtgactgga ttcccagaga tgatggacgg
     8341 tcgtgttaag accctccacc caaacattca cggtgggctt ttggctcgtc gcgacgctga
     8401 cagccacctt caggctgcta aggacaacaa tatcgagctg attgacctcg tggttgtcaa
     8461 cctctatccc ttcaaggaga ctatccttcg tccagacata acctatgatt tggcggtgga
     8521 aaacatcgac atcggcggtc catcaatgct tcgctcagcc gctaaaaatc acgctagcgt
     8581 gaccgttgtg gttgacccag cggattatgc gactgttttg ggagaattgg ctgacgctgg
     8641 tcagacgaca tttgaaacgc gtcaacgctt ggcagctaag gtctttcgtc acacagcagc
     8701 ctacgacgct ttgattgctg agtacttcac aactcaagtg ggagaggcta agcctgaaaa
     8761 attaaccatc acttacgacc ttaaacaggc tatgcgttac ggagaaaatc cacaacaaga
     8821 cgctgatttc tatcaaaaag ccttgccaac agactactca attgcttctg ctaaacagct
     8881 caacggaaaa gaattgtcct tcaataatat ccgtgatgtt gatgcagcaa tccgtattat
     8941 ccgtgatttc aaagaccgtc cgacagtggt tgtcctcaaa cacatgaacc catgtggtat
     9001 cggacaggct gatgatattg agactgcttg ggattacgct tatgaagctg acccagtttc
     9061 aatctttggt ggaattgtcg tccttaaccg tgaagttgac gcagcgacag ccaagaagat
     9121 acaccctatc tttttggaaa tcatcatcgc accatcatac tcagaagaag cgctagctat
     9181 tctcacaaat aaaaagaaaa acttgcgaat ccttgagttg ccgtttgatg cccaagctgc
     9241 cagcgaagtg gaagctgagt acactggcgt agttggtgga cttttggtgc aaaaccaaga
     9301 cgttgtggct gaaaatccat ctgactggca agtggtgaca gaccgccaac caacagaaca
     9361 agaggcgatt gcccttgagt ttgcctggaa ggctatcaag tatgttaagt ctaacgggat
     9421 tattattact aacgatcaca tgacgcttgg actcggtgca ggtcaaacca accgtgtcgg
     9481 ctcagtcaag attgctatcg agcaggctaa agaccacctt gacggtgccg ttctagcatc
     9541 agatgccttc ttcccatttg cggacaacat tgaagaaatc gctgccgcag ggatcaaagc
     9601 aatcatccaa ccaggtggtt cagttcgtga ccaagactct attgacgccg caaacaaaca
     9661 tggcttgacc atgatcttca caggtgtgag acattttagg cattaataaa aaaatgtggt
     9721 ctaattaaaa ccacattttt tattaaaaga aaatataagt taactataat ttgttagctt
     9781 tatcagcatt tacccatgtt ccacgagatc cgatttgaac ataaatacca ttacttggtt
     9841 gatcaatttt taatacttta taactaccag tgacgataaa atattcaccc acacggagaa
     9901 tttgatctcc taaaactttt ccttggttat ctgtttcatc taatggtgtg ggatcaatcc
     9961 agtttagtgg agttgggtct cctccggcta attctttatt aacgatcaaa ttattaacaa
    10021 gctgatctac acgaaaaacg ccagggaagg taacagtatc accgacctta atggaaggtt
    10081 ttgtattgtc attttgaacc acagactgtg cgggctcttt aatgggaata tagcgtcggt
    10141 ttccagaaaa actgaggtag ctaagccatg tataacctcc agcagtcacg actttatcgt
    10201 aataaacaga ttgacctgct tcatagtaag caagatcagg gctatcgata ctggtttgtc
    10261 ctttgactgg taatctggtt gtaaagtgat aagttccaga ggggtcaaat gaagcttgag
    10321 aaatgtgttt tagttgtctt gggtaggaat gacttgtctg agatgataag tctttaaaat
    10381 ggatataacc acttacctga gattttggaa tttgacgctt atggtatctt tcagggcctt
    10441 gtccagcgtt gtaattatac tcttcgatag tgacagtgtc tccacggata tcagctaccc
    10501 atgctacatg accgtaagca gcatttgact gataagcgtt tttatcaaac caagcgatag
    10561 cccctatgct tggtgtctta ttcacaggat aaccctgatt tttcgcgata tgtccccacg
    10621 tgcaggcatt accgtagcct ttaggtaact gaaaaccatt agcagagctt aaacgaaaag
    10681 ctgcaaaaga agtgcattgg cggatataca tgttccacga atcgattcca ttgccttttt
    10741 tccacttact cggatagtta tcgcctaaaa cagctgcatg aacaagattt tcctgttgcg
    10801 aaataagtgt agatggcata gtaggtacta gaccattaaa acctaaaagg attactcctg
    10861 agaccaaaaa acgatgaaat tttttcatta attacctcct gtaacttatt attcgaaagc
    10921 aagaaacaaa aaatgttatt tttagatgat tattttgaaa attggcttta cttgatatta
    10981 aataactgtt tgattggcta atagagtgtt ccttatttca agaattgtgg tctactatca
    11041 catttttaca atgtttcaat tattgataac taatacatta tgtaaaaaaa gcgaacgttt
    11101 atgatataat atctaattat aatacgaaag aggtggatgt tttgaaatta cttgttgttg
    11161 gttcaggtgg gcgtgaacat gcgattgcta agaagttgtt agcgtctaag ggtgtggatc
    11221 aggtttttgt ggcacctggt aatgatggta tgaccttgga tggtctggac ttggtgaata
    11281 tagtagtttc cgaacattct aggttgattg cctttgctaa ggagaatgag atttcttggg
    11341 cctttattgg tcctgatgat gcgctagcag ctggtatcgt tgatgatttc aacagtgctg
    11401 gactcagagc ttttggtcca acaaaggcag cagcggagct agagtggtca aaagactttg
    11461 ccaaggaaat catggtcaaa tacaatgtcc caacagcagc ctatggcaca ttttcagact
    11521 ttgaaaaagc caaagcctac atcgaagagc agggcgcacc tatcgtggtc aaggctgatg
    11581 gcttggcgct aggtaagggt gtggtcgtgg ctgaaaccgt tgagcaggcg gtagaggcgg
    11641 cgcaagagat gcttctggac aataagtttg gcgactcagg agcgcgtgtg gttatcgagg
    11701 aattcttgga tggcgaggag ttttccctct ttgcctttgt taatggtgat aagttctaca
    11761 tcatgccgac agctcaggat cacaagcgtg cctttgacgg agacaagggg ccaaacactg
    11821 gtggtatggg tgcctatgcg cctgttcccc acctgcctca gagcgtggtg gatacagcgg
    11881 ttgagaccat cgttaagcct gtccttgaag gtatgattgc cgaagggcgt ccttatctag
    11941 gcgtcctcta tgcggggctt attctgacgg ctgatggccc taaggttatt gagttcaact
    12001 cacgtttcgg tgaccctgaa actcagatta tcctccctcg cctgacttct gatttcgctc
    12061 agaacatcga cgatatcatg atgggcattg agccttacat cacttggcag aaggacggcg
    12121 tgactctggg cgttgtcgtt gcctcagaag gctatccgct cgattacgag aaaggtgtgc
    12181 cactgcctga aaagatcgac ggcgacatca tcacctacta tgctggagct aagtttgcgg
    12241 aaaatagcga gctacttctc tcaaacggag gacgtgtcta tatgcttgtc accacagaag
    12301 acagcgtcaa agcagggcag gacaaaatct atacccagct agcccaacaa gacccaacag
    12361 gtctcttcta ccgaaatgac atcggaagca aagctataag agaataagac taaccattca
    12421 aatattagcg tcagcaatca acgaccgaag gtcgctccaa aaagaaagaa gaaaggaact
    12481 gaacacggga ctaatttcct aggaaaaaaa taaaactacc tggacgcaag cgtcatcgtt
    12541 agttttctgc gtcgtaggcg tctgatgcta aagcacctag tcgccctgac gtgggttcgt
    12601 cttcgaaatc aaagatttcg gacttaccgc atatttttct acggaaattt tcgacaagtc
    12661 gaaacgcccc tttgtatctt aattatgaaa actccaatta tttctattat catgggctcc
    12721 aaatctgact gggcaaccat gcaaaaaacg gctgaagttc tagacaactt tggcattgct
    12781 tacgagaaga aagtcgtctc tgcccaccgt acgccagacc tcatgttcaa gcatgctgag
    12841 gaagcacgtg gtcgtggcat caaaatcatc atcgcaggag caggtggggc agctcacttg
    12901 cctggtatgg tggcagctaa aacaaccctg cctgttatcg gtgtgcctgt caaatcacgt
    12961 gccctttcag gtttggattc actctattcg attgtgcaga tgcctggcgg tgtgcctgtg
    13021 gcaaccatgg ctatcggaga agcgggagcg actaacgctg ccctgacagc cctccgtatt
    13081 ctctccatcg aggatcaaaa tctggctgat gcgctagctc atttccatga ggaacaagga
    13141 aaaatcgcag aggagtcaag tggtgaactc atttaagacc attgggatta tcggtggtgg
    13201 tcagctgggg cagatgatgg ccattgcggc tatctatatg ggccacaagg tcatcacgct
    13261 ggatcctgct agcgactgcc ctgcctcccg cgttagcgag gtaattgtgg cgccttacga
    13321 tgatgttgag gctttgggac aattggctgc gcgttgcgat gtattgactt atgagtttga
    13381 gaatgttgat gcggacggtt tggatgccgt tgtgtcagct tgtcagctac cgcaggggac
    13441 cgatctgctc cgcatttccc aaaaccgtat cgttgaaaaa gactttctgg caaataaggc
    13501 tggtgtgaca gtcgctccct ataaggtggt gacgtctagc cttgacctag ggggacttga
    13561 tttgaccaag acctatgtcc tcaagacagc gacaggtggt tatgacggtc atgggcaaaa
    13621 gattatccgc tcagcagaag atttgccaga ggtgcagcaa ttagctaact cagctcagtg
    13681 tgtcttggaa gagtttgtca atttcgacct tgaaatctca gttatcgtgt ctggaaacgg
    13741 agaggatgtg acggtctttc ccgttcagga aaatatccac cgcaacaata tcctgtcaaa
    13801 aaccatcgta ccagctcgca tctcagatca actggctgat aaggctaaga aaacggcggt
    13861 gcagattgcc aagaaactcc agctgtcagg aactctctgt gtggaaatgt ttgcgaccgc
    13921 agatgatatc attgtcaatg aaattgcccc acgtccccac aactcagggc actactcaat
    13981 cgaggcttgc gacttttcac agtttgacac ccacattttg ggcgtgctag gagcgccgct
    14041 cccaactatc cacctccatg ctccagccgt catgctcaat gtcctcggac aacacgtcca
    14101 gcaggcgatt gactatgtga ctgaaaaccc tagcgcccac ctccacatgt atggtaaact
    14161 agaagcgaaa cataaccgca aaatgggaca tgtgacacta tttgcagaag atgcggatga
    14221 ggtggaggag ttttaggatg tatctaaagt atatatttaa aataaaggat aggaatttag
    14281 tatcggatta tgaatcttta gttcgaaatt tgacaatcaa tcttcaaaaa ctagttatta
    14341 aagatagaac tgcattaata ggggataaac aacttccaat tacgatatat tatcgtgggg
    14401 agaatgaaaa gtttcctacg ggaatagtaa aagttgaatc agactcagtt gaaggattag
    14461 agttatttga taaaacgata aaggaaatag ttgggaatga aagtagattt ggaaagttca
    14521 catgtatata cgatggaata agtacatatt attcaacaga aatttattct gaacttcatg
    14581 aaattgagcg tcgaacacaa gagtttttaa gagaagcatt ttttctgagc gataaaagtg
    14641 gagaattgaa agaatatcag gcaactatca aaaaaatgga tagtagtgat ttctcattca
    14701 gcaaattaat taatgaaatt tttaaagcaa gcgatataac tgatacattt attgatcatg
    14761 ttagagcgtg tgttgaattt ggaacagttc caaatggaga tttattacca aaaagttttt
    14821 gggatagttt agataactct ttactagatg ataaagagca aggtttagag attaataatt
    14881 tattaaatga gattcgttca acaagaaata caatagctca ctgtaaagag tttaaaaaga
    14941 aggattatat taattgtata gaacaagtta aaaaattaaa gcaagcattg gataaaataa
    15001 tagcctctat agagtctaca gatatttcta aaatgtcacg agaagtgtca cgcataaata
    15061 actccttaca agccgataat gactacatca aacaaaaata ttttatagaa tatgatattt
    15121 ttgaaaagga tatattagct aggacagggt tattagaaat tgattgggaa aacgtttctg
    15181 atgacataga gcccttaaag atacatcgta acttttatga atcaattagt gaaaaaacag
    15241 attctgaagt tatagaagag atcaaaaatt tagaagatat aaatttcact gatgaaaagg
    15301 gtaatgattt ggatgactta accattattg ttcctgcgca agacgaagga tttaaaagag
    15361 tctttctagg tcaacgagaa tggtatgata tacggatagg aaaatcgaaa aggaatagga
    15421 ttaaatatat cgcaggatat gaagttgcac cagagagtgg tgtaaagtac tgggctgaag
    15481 tggataaaat agttccttca gataactatg ttggttactg gaaagtaatt tttaaaggag
    15541 aggtgaagga atattcagaa tataaaaaat taggaaatac ttggccccct caaaacagta
    15601 gatacgtatc taaaaaggct ttagatgaag ctaagtattt atcggatgtt ttttaattaa
    15661 aggagaaaaa acaaaatgat ttcacgttat tcacgccctg agatggcggc aatttggaca
    15721 gaggaaaata aataccgtgc ttggttggag gtcgagattt tggctgacga ggcatgggca
    15781 gagttgggtg agattcctaa ggaggatgtg gctaagattc gtgagaaggc ggattttgac
    15841 attgaccgca ttcttgaaat tgagcaggac acgcgtcacg atgtggtggc tttcacgcgt
    15901 gcggtttctg agacgcttgg tgaggagcgc aagtgggtgc actacggttt gacgtcaact
    15961 gacgtggtgg acactgccta cggttacctc tacaagcaag ctaacgacat tatccgtcgc
    16021 gatcttgaga atttcaccaa tatcgtggca gacaaggcgc gtgagcacaa aatgaccatc
    16081 atgatgggtc gtacccacgg tgttcacgcc gagccaacga ctttcggtct taagttggcg
    16141 acttggtaca gcgagatgaa acgtaatatt gagcgttttg aacatgctgc cgcaggtgtg
    16201 gaagctggta agatttcagg tgccgttggt aactttgcca acatcccacc ttttgtggaa
    16261 caatatgtct gtgacaaatt aggcattcgt ccgcaagaaa tttcaacaca agttcttcca
    16321 cgtgaccttc acgcagaata ttttgcagtg cttgcaagta ttgcaacatc tatcgaacgt
    16381 atggcaacag agattcgagg tctgcaaaag tcagaacaac gtgaagttga agaattcttt
    16441 gccaaaggtc agaaaggtag ctctgctatg cctcacaaac gcaacccaat cggttcagag
    16501 aacatgacag ggctagcgcg cgtgattcgt ggtcacatgg tgacagctta tgagaacgtg
    16561 tcactttggc atgagcgtga catttcgcac tcatcagctg agcgtatcat cacacctgac
    16621 acaactatct tgattgacta catgctcaac cgctttggca atatcgttaa gaacttgact
    16681 gtcttcccag aaaatatgat gcgcaatatg gaatcaactt ttggtttgat ttatagtcaa
    16741 cgtgttatgc tcaaattgat tgaaaaagga atgacacgag aagaagctta tgacttagtt
    16801 caacctaaga cagcttattc ctgggacaat caagtggatt tcaaaccact tttagaagaa
    16861 gacatcaaag ttacctcttg tcttacacaa gaagaaattg atgaactatt taatccgatt
    16921 tattacacaa aacgtgttga tgatattttt aagcgtttag ggatttaata taaaaaaaga
    16981 aggtgattcc cttctttttt atttaaaaaa cgaatatttt ctttaaaaat attaaaaagg
    17041 ttagttttta attagacgct gtgatataat aaagaaaaca gttgttggag agaaaccatg
    17101 ttagaacatt ttggtggaaa agtaaaagtg ttaagacttg aaaagaggat tagtcgcgag
    17161 gacttgtgtg gggatgagtc tgaactttct gttcgtcaat tagcacggat agaactaggt
    17221 caatccatac caagtttaag taaggttatt tttattgcaa aagccttaaa cgttagtgtc
    17281 ggttacttaa ctgatggtgc tgatttagaa ctacctaagc gttacaaaga attaaaatac
    17341 cttatcttaa ggacaccaac ttacatggat gatggaaaat tacaagtacg agaagagcag
    17401 tttgatgaaa tttttgagga ttattatgat aaattaccag aggaagagaa aataatcatt
    17461 gattgtttac aggcaacttt agatacttta ttgagtgaga atactaactt tggcattgac
    17521 ttacttcaag aatattttaa tcaaataaag actaaggtac gctttaggca aaatgat
//
LOCUS       DAUGOH010000032        16097 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUGOH010000032 DAUGOH010000000
VERSION     DAUGOH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16097
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.032"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..189
                     /locus_tag="VH957_001259"
     CDS             <1..189
                     /locus_tag="VH957_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HEQ8559171.1"
                     /translation="KLKVHKNTILKYLKKLVEKQAIDKFKSGRQYVYFIAQNQDPEFQ
                     KYNHIDAMYSLLEEMKRK"
     gene            284..1180
                     /locus_tag="VH957_001260"
                     /pseudo
     CDS             284..1180
                     /locus_tag="VH957_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481078.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            1275..1511
                     /locus_tag="VH957_001261"
     CDS             1275..1511
                     /locus_tag="VH957_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEQ8559172.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            1504..2202
                     /locus_tag="VH957_001262"
     CDS             1504..2202
                     /locus_tag="VH957_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEQ8559173.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLKQGYHVYGVDKSDKPDLNGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLAEWVARETPIGRWTKPSEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            2278..3237
                     /locus_tag="VH957_001263"
     CDS             2278..3237
                     /locus_tag="VH957_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8559174.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKTAKDLA
                     KAYHMPLVTSKYEAILGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKTTIQGNKGSLAVLGATNTLPQVQLSLYGHEAQVVNHNKH
                     DHRMYEEFVAFKDMIDQKDFEKVNQALEHSRAVMAVLERAVHS"
     gene            3570..4907
                     /locus_tag="VH957_001264"
     CDS             3570..4907
                     /locus_tag="VH957_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8559175.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGILVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISILEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            5080..6462
                     /gene="glmU"
                     /locus_tag="VH957_001265"
     CDS             5080..6462
                     /gene="glmU"
                     /locus_tag="VH957_001265"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEQ8559176.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGQGSIITNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDNALTAAGSTISKTVPADSIVIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            6493..7047
                     /locus_tag="VH957_001266"
     CDS             6493..7047
                     /locus_tag="VH957_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8559177.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIESVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQIANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            7047..7298
                     /locus_tag="VH957_001267"
     CDS             7047..7298
                     /locus_tag="VH957_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559178.1"
                     /translation="MGRPLLTDDIIEKARRMETFESDDAVDFDTKVMTLPEKDEKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            7318..8013
                     /locus_tag="VH957_001268"
     CDS             7318..8013
                     /locus_tag="VH957_001268"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEQ8559179.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQTLMTFLENLPV"
     gene            8164..8505
                     /locus_tag="VH957_001269"
     CDS             8164..8505
                     /locus_tag="VH957_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559180.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNGGYRQGLTD
                     EKSKLQYSKDNAKLQLRNILNGYQSDLGKHYSSYYYYNLRTVMGLSSEQDIEEHYKKL
                     KNKLHDMYNHY"
     gene            complement(8604..9251)
                     /locus_tag="VH957_001270"
     CDS             complement(8604..9251)
                     /locus_tag="VH957_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEQ8559181.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILNFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYDDKDLVIPENIAKQLYVTAL"
     gene            9397..10329
                     /locus_tag="VH957_001271"
     CDS             9397..10329
                     /locus_tag="VH957_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEQ8559182.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            10393..11118
                     /locus_tag="VH957_001272"
     CDS             10393..11118
                     /locus_tag="VH957_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559183.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            11119..11973
                     /locus_tag="VH957_001273"
     CDS             11119..11973
                     /locus_tag="VH957_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8559184.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLGVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(12121..12927)
                     /locus_tag="VH957_001274"
     CDS             complement(12121..12927)
                     /locus_tag="VH957_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ8559185.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            13144..15549
                     /locus_tag="VH957_001275"
     CDS             13144..15549
                     /locus_tag="VH957_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8559186.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMPKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDRPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGSAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(15619..15972)
                     /locus_tag="VH957_001276"
     CDS             complement(15619..15972)
                     /locus_tag="VH957_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEQ8559187.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDIALLLFA
                     VEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
BASE COUNT         4919 a         2748 c         3530 g         4900 t
ORIGIN      
        1 aaactaaaag tccataaaaa tacaatttta aaatatttaa aaaaattagt ggaaaaacaa
       61 gctatcgata aattcaaatc tggtagacaa tacgtatact ttattgcaca aaaccaagat
      121 cctgaatttc aaaaatataa ccacattgat gccatgtatt ctctactgga agaaatgaaa
      181 cgcaaataat ggtcttctcg taagcttaag catgatataa atccaatcta acaccgtttt
      241 gataggagct tgcctgctga tgctgatgga aaggtttatg atcatgaaaa taacagaagt
      301 taaaaagaaa gatggtacta ttgtctaccg tgctagtgtt tgccttggta ttgatcaggt
      361 aacaggtaag aaagtaaaaa tcagtgtaac gggtaagacg caaacagagg ttaagcagaa
      421 agccaaacac gcgcagtttg attttatatt taatggatct acaatatgta aagaagcaca
      481 gattaggaat tatcaggagt tggcagaact atggctaaag agctatcagc tcactgttaa
      541 gccacagaca tatgtagcga ctaagagaat gctttacaat catttaatac ctgtttttgg
      601 atctatgaaa attgataaat taactgtcag ctatatccaa cactttataa atgacttatc
      661 aagtcagtca gaccattacg gtgtagtgca ttcgacaaat agacgtgttt tacagtatgg
      721 tgtatctctc caacttattc caaagaacta cagtaggtta ttaaaactat taggtacacc
      781 aaagagtaaa gcaagaatta gggcaatcag tatcgacaag aaaacagtta atatgttaaa
      841 gctttacaag aagagacagc gacaactgtt tttagaagtc ggcggttgtt ctcctaaggt
      901 ggtttttgct actccaacca aagaatatca aaacatggcg acaagccagg agtgtttaaa
      961 cagatgatgc aaggaaatag atattcctcg ctttacctct cacgctttta gacatactca
     1021 tgctagttta ttggtaaatg ctggtatcag ctataaagaa ttacaataca gatcaggtca
     1081 tgccactttg gctatgacta tggatagtta tagtcactta tcaaaagaca aagaaaaaga
     1141 accagtatct tattatgaaa aagcaataaa tagcttctag gtgaactaaa aggcgaccaa
     1201 atgtttaaaa ttacatttta taacattcac aaaatctatt atatcaacgg atatagtcaa
     1261 taaaggagaa caatatgaca tttgaagaaa ttctaccagg tttaaaagcc aagaaaaaat
     1321 atgtacgtac aggttggggt ggcgctgaaa attatgtgca gttgtttgat acccttgaag
     1381 tggatgggaa agtactacag gcgacgcctt attttctgat tcatgttact ggtgcaggtg
     1441 aaggtttttc catgtgggca ccgacaccat gtgatgtgtt agcagaggat tggatcgagg
     1501 tcaatgacta aagttgtttt agtgacgggc tgtgctagtg ggattggtta tgcacaggcc
     1561 cgctattttt tgaaacaagg gtatcacgta tatggtgtgg ataagtcgga taagccggac
     1621 ttaaacggta attttcactt tatcaaattg gatttatcct ctgagttatc cccactattt
     1681 aaagtggtcc ccagtgttga tattttgtgt aataccgcag ggattttaga tgcctacaag
     1741 ccacttttag acgtcagtga tgaagaagtg gaacacctat ttgatattaa tttttttgcg
     1801 acggtgaagt taacacgtca ttatcttaga cgtatggtgg aaaagcagtc aggtgttatc
     1861 atcaatatgt gctcaatagc aagttttata gcgggtggcg gtggtgttgc ctatacgagt
     1921 tctaagcatg cccttgcggg attcacgcgc cagctggctt tggattacgc caaagatcag
     1981 attcacatct ttggtatagc gccaggtgct gtcaaaactg ctatgacggc tagcgacttt
     2041 gagcctggtg gcttagcaga atgggtagct cgtgagacgc caattgggcg ttggactaaa
     2101 ccaagtgaag ttgctgaatt gacgggattt cttgcttcag gaaaagcgag atcaatgcaa
     2161 ggtgaaattg tcaaaattga cggtggctgg actttgaaat gatcacatgc cttagcttga
     2221 gctggcgcag taagccctag aggtgtgacg agtcaaacag tcaaaggaga tgaacaaatg
     2281 aaattagcgg ttttggggac aggtatgatt gttaaggaag ttttgcctgt cttgcagaaa
     2341 attgatggta ttgatttagt tgctatctta tcaacagtta gaagtttaaa gacagctaaa
     2401 gacctcgcta aggcatatca catgcctcta gttacgagta aatatgaggc tatcttaggc
     2461 aatgaggaga ttgacacagt ttatattgga ttgccgaatc acctgcattt tgcctatgct
     2521 aaggaggctc ttttggctgg taaacatgtc atttgtgaaa agccctttac catgacagca
     2581 ggagaattag atgaactggt ggtgatcgct aaaaaacgaa aactcatttt gttagaagcg
     2641 attacgaatc agtatttaag taacatgact tttatcaaag agcatcttga ccaacttggc
     2701 gatatcaaaa ttgtagaatg caattattca caatattctt cacgctacga tgccttcaaa
     2761 cgaggtgata tcgcgccagc ttttaatcct aaaatgggtg gtggggcttt acgtgattta
     2821 aacatctaca acattcattt tgtggtagga ttatttggtc gccctaaaac ggttcaatat
     2881 ttagccaatg tcgaaaaagg cattgacaca tcaggcatgc ttgtcatgga ctatgagcag
     2941 tttaaagtgg tgtgtattgg ggccaaagac tgcactgcgg aaatcaaaac aaccatccaa
     3001 ggtaataaag ggtcactggc agtgcttgga gcaacaaata cccttcctca ggttcagtta
     3061 agtctgtacg gtcacgaagc acaagtggtt aatcacaaca aacatgacca ccggatgtat
     3121 gaggagtttg tcgcttttaa agacatgatt gaccaaaaag actttgagaa agtgaatcag
     3181 gctttggagc atagccgagc tgtcatggct gtgttggagc gtgctgttca ttcgtgactg
     3241 taatctggta gccattgcct tttgtgcagt tgctatggta atggttgaaa gacgtgtttt
     3301 cacgagggtt aaccccctcg tgcttttttg gcaaaaataa cttgttcagg atttgggcct
     3361 tctttgtgag atgagagatg cctgacgaat tgatttgatt aaaataatga taaagccaaa
     3421 cgatttaaga aatgaccgtt cggaaattct gccccaaaag gtctctagaa gcagtgaaat
     3481 cgaatttgta agcgttgaca ctactgcata actctgttac actaagagaa tgtcatgaca
     3541 aaaattacag tgtaggagtt taattgttta tggaagagga ttataacaaa agagaacctg
     3601 agaagtttac gcaatttctg cgccgtcaaa aggttgtctt ttttgtcgca ttttttggtt
     3661 atgtgtgtgc ttacttggta cgcaacaatt tcaaactaat gtcaaacact attatggtgc
     3721 aaaatggttg ggacaaggct caaattgcga ccttgttatc gtgtttgacc gtttcttatg
     3781 gcttagcaaa attctatatg ggagccttag gggatcgtgt tagcttgaga aagctctttt
     3841 cgatcagctt gggtgcaagc gctttgattt gtattttaat cggttttttc aatagttcaa
     3901 tggtggtgtt agggatactg ctagtcttgt gtggtgtcgt acaaggtgcc ttggcacctg
     3961 cctcacaagc catgattgcc aattattttc caaataaaac acgcggcgga gccatcgctg
     4021 gatggaacat ttctcaaaac atgggatcag ccctcttgcc attaaccatc gccttgctca
     4081 ccagtatggg cttggtggta ccagctaatg gcaatatttt acttgccttt ttaatccctg
     4141 gcattttagt gttcttgttt gctttgtgtt gctggaagct tggcggtgat aaccctgagt
     4201 ctgaaggact tgactctctt cgaacgatgt atggtgatgc gggcgagtca gctgttgcca
     4261 gtgaagaaga aaagcataac ctgtcttatt ggcaactcat ctggaaatac gttttttgta
     4321 acccgtcgct cttacttgtt gctgctgtca atgtagccct ttattttgtt cgttttggga
     4381 ttgaagactg gatgccgatc tacttgtcac aagtagccaa tatgtcagag gctcatatcc
     4441 attttgcgat ttcaatatta gagtgggtag ctattccagg ctcgctggta tttgcgtggt
     4501 tagcggttcg ttatcctaat aaaatggcca agattggggc tattggactt tttgtgttgg
     4561 cggctattgt gtttgtctat gaacgcttga ctgccacagg tgctccaaac tatttcttgt
     4621 tgcttgttat tgcaggtatt ttagggtcat tgatttatgg cccacagttg atcgtgaata
     4681 ttttaacaat caactttgtt cctttaaatg ttgcaggaac agcgattggt tttgtaggag
     4741 taacagctta tctcatcggc aatatgggag caaactggct gatgccgatt ttggcagatg
     4801 gttttggctg gttttggtca tatattgtcg ttgcagcctt atctgctttt tcagcggttg
     4861 gttatttgat tttagccaaa cgtgaggaag aaatcatcaa agattagcta ggcaaatgcc
     4921 taagaaagac agacttattg ctgaagtact gtctttttta gtcatcacaa gccgcaaatg
     4981 acactataaa agataagaaa atgctaggat gtttcaggaa aaaaagagaa aatatgctat
     5041 aatgagaagg tatttaaatt atatagtaag gaaaaacaaa tgacaaatta tgccattatt
     5101 ttagcagcgg gcaaagggac tcgcatgact tctgatctcc caaaagttct tcataaagta
     5161 tctggactaa ccatgcttga gcatgttttt cgtagtgtaa aagcgattag tcctgaaaaa
     5221 tccgtgacgg ttattggtca caaatcagaa atggtacgtg ctgtcttagc agatcaatca
     5281 gcctttgtcc atcaaacaga gcagttagga actggccatg ctgtgatgat ggcagaaaca
     5341 caactagaag gactagaagg gcataccttg gtgattgcag gagatactcc tttgatcact
     5401 ggagaaagcc tgaaaagtct gatcgatttt catgtgaatc ataaaaatgt cgccactatt
     5461 ttaacagcta cggctcaaga tccatttggt tatggtcgta ttgttcgcaa caaagatggc
     5521 gaagtgatca agattgttga gcaaaaagac gccaatgagt atgagcaaca attaaaagaa
     5581 atcaatacag gaacctatgt gtttgataac aagcgtctct ttgaagcgct caaatgcatc
     5641 actaccaaca atgctcaagg agagtattac ctgactgatg ttgtggctat ttttagagca
     5701 aacaaagaaa aggtaggagc ctatatcctg agagacttca atgaaagtct tggtgttaat
     5761 gatcgtgtgg ccttagcaac agctgaaaca gtgatgcgcc aacgcatcac ccaaaaacat
     5821 atggtcaatg gggtgacttt ccaaaatcct gaaaccgttt atattgaaag cgatgttgag
     5881 attgctccag acgtccttat cgaaggaaat gtgaccttga aagggcgtac acatatcggc
     5941 tcaggaactg tcttgacgaa tggtacttat attgtggatt ctgaaattgg tcaaggaagt
     6001 atcatcacca actcaatgat cgaatcatct gttttagctg caggagttac ggtaggccct
     6061 tacgcccacc ttcgaccagg aacgacctta gatagggaag tccatatcgg taactttgtt
     6121 gaggtcaagg gttctcacat tggtgaaaaa acaaaggctg ggcatctgac ttatattgga
     6181 aacgctcagg ttgggtcttc agtcaatgtt ggggctggaa ccatcactgt caactacgac
     6241 ggccaaaaca aatatgaaac agtcattgga gatcacgctt ttattgggag caactcgact
     6301 ctcattgcac ctttggaagt tggagataat gctttaactg cagctggctc aacgatttct
     6361 aagacagtac cagctgatag cattgttatt ggtcgtagcc gtcaagtcac aaaagaaggt
     6421 tatgccaagc gcctagcgca tcacccaagt cgaagcaaat aattcaagat ctatttagta
     6481 aggaggccag gcatgaaatt tgaagaaaaa acgcttaaga gacaaacagt ttttgatggt
     6541 catattttta aagttgttgt ggatgatgtt gaacttccca acaatctggg gcaatccaag
     6601 cgagaattaa tttttcatcg tggtgccgtt gctgttttgg ctattactcc tgaacgtaag
     6661 attgtccttg tcaaacaata ccgtaaggct attgaaagtg tctcatacga gatcccagcg
     6721 ggtaaactag agattggtga ggaaggctca aagctaaaag ctgctgcacg tgagctagaa
     6781 gaagaaacag cctatacggg gacattgacg tttttgtatg aattttatac agcgattggt
     6841 ttttgcaacg aaaaaatcac acttttctta gcgacagacc taacacaaat tgccaatccc
     6901 aaaccacaag acgacgatga agttatcgag gtcttagagt tgacatatca agagtgcatg
     6961 gacttagtcg ctcaaggtaa acttgctgac gctaaaacgt tgattgcttt gcaatactat
     7021 gccttacatt ttggaggtga gcagtgatgg gaaggccatt gttgaccgat gatatcatcg
     7081 aaaaagcgag acgaatggaa acatttgagt cagatgatgc tgtagacttt gacacaaaag
     7141 taatgacgct accagaaaaa gatgaaaaag cccgcattta taaaagccgt cggattgaaa
     7201 atgccaaacg cagccaattg caatctaaat taaatgtgat tttgatagct gttatgctgt
     7261 taattgccat cttggtatat gctatctttt atctttaaaa aaacgtaagg aaatgatatg
     7321 aaaataggaa ttattgctgc tatggaggag gagttgtccc tgctcttagc aaatcttttg
     7381 gatgctcaag aacatcaggt gctttcaaaa acttactata cgggtcgttt tggcaagcat
     7441 gagctcattt tggtacagtc aggtgttgga aaagtgatgt ctgctatgac agttgcgatc
     7501 ttggttgagc atttcaaagc ccaagctatt atcaatacag gatcagcagg ggcagtcgct
     7561 tcacatttag cgatcggaga tgtggtggtt gcagatcggt tagtgtatca tgatgtggat
     7621 gctactgcat ttggttatgc ttatggtcaa atggctggtc aaccattata ctatgattgt
     7681 gatccacagt ttgtggctat cttcaaacaa gtcctaaaac acgaaaagac aaatggccaa
     7741 gttggtttga ttgcaacagg agacagtttt gttgctggtc aggacaagat tgaccagatc
     7801 aaaacagctt ttagcgacgt gttagcagta gaaatggaag gcgcagctat tgctcaagca
     7861 gcacatactg caggtaaacc tttcatcgtt gttcgtgcga tgagtgatac cgcagcgcat
     7921 gatgccaata ttacttttga tcaatttatt atagaagctg gcaagcgttc ggcccagaca
     7981 ttaatgacat ttttagaaaa cttacctgtt taactcacct tatcgtgaga caattagctg
     8041 gataatctct attttaggag tctggtcacc tcttgttttg aaacctaaaa ataagaattg
     8101 caatcacttg accaaacgct ataatgggtt aaggaacgat agattactaa aaggagtcta
     8161 aaaatgacac taaaaaaaca ctattatctt ctcagtctgc tagctcttgt aacggttggt
     8221 gctgccttta acacaagcca gagtgtcagt gcacaagttt atagcaatgg aggatatcgt
     8281 caaggtttga ctgatgaaaa atcaaagctg caatatagta aagacaatgc caaacttcaa
     8341 ttgagaaata tccttaacgg ctaccaaagt gacctaggga aacactactc tagctattat
     8401 tactacaacc taagaaccgt tatgggacta tcaagtgagc aagacattga agaacactat
     8461 aaaaagctta agaacaagct acatgatatg tacaatcatt attaagtcaa aggcttaaaa
     8521 atggcgacta gcccctcaaa aaaagaggcc acactcattt aaatttaaat gagtgtggcc
     8581 tctttttgag gagacgcaag gggttaaaga gctgtgacat agagttgctt agcaatattt
     8641 tcagggatga caaggtcctt gtcgtcataa caaatcgtat aggtttttgc aaaggtatca
     8701 atttgagtta aggttagctc ggtattgata ttgaggtgat gtgcttctag atactggatt
     8761 aaatcaaagt ggtcgtggat tctgcttagg cgaaaccgtc ccaactccgt gatggtgttg
     8821 agagttgtag tgttcatttc gacaagaggc tgaccatagc gaggaatagt ccctccgtgt
     8881 gggcagaaat ctggaaaatt aaggatcttg tctaaacggt cgataaaggt gtctgagaca
     8941 gtgtgctcta agacttcagc ttcttggtgc acttcttggg tattatagcc cagctggtga
     9001 atcaaaaata cctcaatcaa gcggtgtttg cggtagaggt tagcaacaag agcatagcct
     9061 ttgtctttta gcaaatagcc ttttgcttta tctttgacaa tccagccttg tgaaatcatt
     9121 tttttaatca tctctgaaac ggcaggtgcc gaaacgtgca tcttttctgc aaccatttta
     9181 tttgtaatct tgggttcttg ttctccaatt tcataaatac atttcaagta atcttcttta
     9241 ttaggcgtca tatcgtttgg cctttctctt atttataatg attattatat cagaattttt
     9301 aggaaaaagc ttgacaaaaa gcctaaaaga ggatatcctt atagcataat taactaaact
     9361 taattaaata aataatatat cctaaggaga gaaatgatgg gaaagagaat gagcctcatt
     9421 ttgggtgctt ttttatctgt ttttctttta gtagcttgtt cgtcaactgg cactaaaact
     9481 gctaagagtg ataaattaaa agtcgtggca accaattcaa ttattgccga catgacaaaa
     9541 gctattgctg gtgataaaat cgatctgcac agcattgtgc caatcggtca agatcctcat
     9601 gagtacgaac cattaccaga agatgttgaa aaaacaagta atgctgatgt gattttctat
     9661 aatggtatca atctagaaga tggtgggcaa gcttggttca ccaaactagt gaaaaatgct
     9721 caaaaaacga aaaacaaaga ttactttgcc gtgtctgatg gcattgatgt gatttacttg
     9781 gaaggtgcaa gcgaaaaagg aaaagaagat ccacatgctt ggttaaatct cgaaaacgga
     9841 atcatttatt caaaaaacat tgccaaacaa ttgattgcaa aggatcctaa aaacaaagaa
     9901 acttatgaaa agaacctaaa agcttatgtg gctaaattgg aaaaactaga caaagaagcc
     9961 aaatcaaaat ttgatgctat tgcagaaaat aaaaaattga ttgtgactag tgaaggctgc
    10021 ttcaagtact tttcaaaagc ttacggtgtc ccatctgctt atatctggga aattaacacc
    10081 gaagaagaag gaacaccaga tcaaatttca tcattgattg aaaaactaaa agtcatcaag
    10141 ccatctgcgc tttttgtaga gtcaagtgtc gatagacgcc ctatggaaac tgtttctaaa
    10201 gatagtggta ttcctattta ttctgagatc tttacagatt caattgctaa aaaaggtaaa
    10261 cctggcgata gttattatgc tatgatgaaa tggaaccttg acaaaatttc tgaaggtcta
    10321 gcaaaataag ataacaataa agcacagcga ttttagtgtt gtgctttgtt ttatttatgt
    10381 aaaggagaca aaatgattac aactaacaat ctttgtgtga cctacgatgg caacagtaat
    10441 gctttagaag cgattaatgt gacaattgaa ggtccttcta tcgttggtat tatcggtcct
    10501 aatggagctg gaaaatcaac ctttatgaaa gctatcttaa atcttattga ttatcaaggt
    10561 cacgtaacgg ttgatggcaa agatggtcgt aagcttgggc atacagtagc ttacgtagaa
    10621 caacgaagca tgattgacta taattttcct attactgtta aagaatgtgt ggcgctaggg
    10681 acttatagta aattaggcct ttttcgccga gtaggaaaaa aacaatttga gcaggttgat
    10741 aaggttctca aacaagttgg tttagaagac tttggccatc gaccgataaa atccttatct
    10801 ggtggtcagt ttcagcggat gttggttgcg cgttgcttga ttcaagaatc agactatatt
    10861 ttcttagatg aaccgtttgt tggcattgac tcggtcagcg aaaaaatcat tgtagatctt
    10921 ttgaaagagc tcaaaatggc tggcaaaacg attttaattg tacatcatga tttgagcaaa
    10981 gtagagcatt attttgacaa actcatgatt ttaaataaac atttggtggc ttatggcaac
    11041 gtttgtgagg tatttactgt tgataccttg tcaaaagctt atggcaatca tttgatttta
    11101 ggaaaggaga tggtgtaaat gtctatgaaa ttttttgagg gcttgatgtc ataccacttt
    11161 ttacaaaatg cactgataac ggctgtagtc attggtatcg tctcaggtgc tgtagggtgt
    11221 tttattatcc ttaggtcaat gtctcttatg ggtgatgcca tctcacacgc tgttttacca
    11281 ggggttgctt tgtcatttat tttaggagtc aattttttta ttggagcgat tatttttggg
    11341 ttattagctt ctgttattat tacttatatc aaggaaaact ctgttattaa aggagatacg
    11401 gctattggta tcacctttag ctcttttttg gcactgggag tcatcttgat aggggtagcc
    11461 aatagttcga cggacttatt tcatattttg tttgggaata ttttagctgt gcaagatagc
    11521 gataagtgga ttactattgg tgtttcgatt tttgttttag gggttattag tctctttttc
    11581 aaagaactat tattaacatc atttgatcct atcttagcca aatcaatggg tgtgaaggtc
    11641 aatgcgtatc attatttgtt gatggttcta ttaactttag tggctgttac ggcgatgcaa
    11701 agcgtgggta ctatcttgat tgttgcctta ctgattacgc cagcagcgac agcttattta
    11761 tatgctaata gcttaaaagt aatgttagtg atgtcatctt tactaggtgc tttagcatcg
    11821 gttttagggc tttatttggg ctataccttt aatgttgccg cagggtcaag tatcgtactg
    11881 acttctgcga tgatgttttt gatcagtttc tttgtttcac ccaagcaagg ctacctcaaa
    11941 agatggatgc aaaaaaaaga aaaaacacct taaacttttc gctttaaaca ccttagtggt
    12001 ttgcaaatag tggcaaatga catcaaaggg tgttttttat atgtcatcaa aagaccataa
    12061 aaaaccttat caaaccaagg tatttagcct attatctgat aaggtttttt taagcatgat
    12121 ttagttttta aagcgataat ctttgacaat gtcaattgag gtaatcgtaa tgtcttgttc
    12181 tggtttatca ttttggttga tagaagtcgc ggcaatttta tcgacaacat ccataccatc
    12241 aatgacttga ccaaatacag tataaccgcc atctaagctt ggattgccgc catgctcata
    12301 ggcagagatg ataggttttg ggtagttggt acttgataat cccttgcttt gatttttctt
    12361 gttttggttg atataaaatt ggctaccgtt cgtattagcg ccagcatttg ccatggcaag
    12421 agcaccgcga atatgatata aaaatggaga gatttcgttg acaaagccat tgccagcatc
    12481 ttttttagga tccttgccct tccaaatcga ttcaccacct gtgccatctc ctttggggtc
    12541 acctgattga atcataaagt cgttgatcac acgatggaag gtaaggttat catagtagcc
    12601 ttttttagca tgggtgagga agttctcaac agctaaggga gcatattttg ggaataactt
    12661 aagggtgatg tccccttgac ttgtcctcat tacgacctta gcttcttctt tgccgacttc
    12721 tttggttagt tgtggaaatt ggctagcatc agctttgaga gctttttgaa tgctttcttc
    12781 ataggcttta gaagctgctt cgctttcttc tttggcagtt ttttcatcaa tgtatttatc
    12841 gccttttata gcgcggtcaa cagattcaca agcactcaaa ctaagtaaac taatggctac
    12901 taaactgaga gataataatt ttttcatgtc tactcctaag aatgattttc tttattttat
    12961 cataaaatgc aacagaaaat agtagtaaag agttaaaaac gcctattttt gtgttttatg
    13021 atctaacctt ggttaaaagg ctgctacgac tgttattata gcacaagatg ctatagaaaa
    13081 acttaaaaca ccttggtttt ttagagctat ttcctaatag ttaaaaaatg gtataatagt
    13141 gttatggtta aaagaaatca aagaaaaaaa agtgcgccta agaagcgttt aacaaaagca
    13201 gaagtggaaa agcaacgtgc cattaagagg atgattttat ctgttttaat ggctttgttg
    13261 cttatttttg cgatgcttcg cttgggcgtc tttggcgtga caacttataa tatgattcgt
    13321 tttttggtgg gtagtttagc ctatccgttt atgtttgcct ggttaattta cttattttgt
    13381 tttaaatggt tacggcaaaa agatggaatg attgcgggag ttgttattgc ctttttggga
    13441 ttgctagttg agtggcacgc cttcttattt gcgatgccta ggatgcttga tcaagatatt
    13501 tttctaggca ctgctcggct aattacaaga gatttactag ccctgcgcgt gactgaattt
    13561 gttggtggag gaatgcttgg tgcattactt tataaaccca tagccttttt attttcgaat
    13621 atcggctctt actttattgg ttttttgttt atcttattag gattatttct aatgacgcct
    13681 tgggatatct atgatgtgag tcactttgtg aaagaggctg ttgataaact agcagtggct
    13741 tatcaggaaa ataaagaaaa gcggttcatc aaacgagaag agcaccgctt acaagctgaa
    13801 aaagaggctt tagagaaaca agcacaagag gaagaaaaac gtctagcaga attgacggtt
    13861 gatcctgaga cgggagagat tgttgaggat agtcagtctc aagtcagcta tgatttggct
    13921 gaggatatgc caaaagagcc agagattctt gcttatgata gtcacctcaa agacgatgag
    13981 gcaagcttat ttgaccaaga agacttggct tacgctcatg aggaaattgg ggcttatgac
    14041 tctttatctg ctttagcatc ttctgaagat gagatggata tggatgaacc tgttgaagtt
    14101 gatttcacac caaaaaccca tcttctttat aaacttccaa cgatagattt atttgcacca
    14161 gataggccca aaaaccagtc caaagagaaa aacttagtcc gcaaaaatat caaggtgctt
    14221 gaagatacct tccaaagttt tgggattgat gtcaaggtag aacgtgctga aattggacca
    14281 tcagttacta aatatgaaat caagccagct gtcggggtcc gagttaatcg tatttcaaat
    14341 cttgctgatg atttggcact tgctctggct gctaaagatg ttcgtattga agcgccaatt
    14401 cctggaaaat ccttaatagg tattgaagtt cctaactcag aaattgcaac ggtttctttc
    14461 cgcgaacttt gggaacaatc tgatgccaat cctgaaaacc ttttagaagt accactaggt
    14521 aaagctgtta atggcaacgc tcgcagtttt aacttagcta gaatgccgca tcttttggta
    14581 gctggttcaa ctggttcagg taaatctgtg gcagttaatg gcattatttc aagtattttg
    14641 atgaaggcac gtccagatca agttaagttt atgatgattg accccaaaat ggttgaatta
    14701 tctgtttata atgatattcc acatctatta atcccagttg taaccaaccc gcgtaaagcc
    14761 agtaaggcac tccaaaaagt ggttgatgag atggaaaacc gctacgagtt atttagcaaa
    14821 attggtgtgc gtaatatagc aggttataat acaaaggttg aagagtttaa tgcttcttct
    14881 gagcaaaaac aaataccgtt gcctttaatc gttgtcattg tagatgaatt ggctgacttg
    14941 atgatggtgg ctagtaaaga agttgaagat gctattattc gtttgggaca aaaagcacgt
    15001 gctgcaggta tccatatgat tcttgcaact caacgtccct ctgtagatgt tatttctggt
    15061 ttgattaaag caaatgttcc gtcgcgtatg gcatttgctg tttcaagtgg tactgatagc
    15121 cgtacaatcc ttgatgaaaa tggtgctgaa aagctcttgg gacggggtga tatgctcttt
    15181 aagccgattg atgaaaatca ccctgttcgc ttgcaagggt ctttcatctc agatgatgat
    15241 gtggagcgta ttgtcaactt tatcaaagac caagctgaag cggattatga tgacgccttt
    15301 gatcctggtg aagttagcga caatgatcct ggtttttctg gaaatggcgg atctgctgaa
    15361 ggtgatcctc tttttgaaga agcaaaagcc ttggtcttag aaacacaaaa agctagtgcc
    15421 tcaatgattc aaaggcgttt gtcggttgga tttaatcgtg ccacgcgctt gatggatgaa
    15481 ttggaagaag caggtgttat cggtccagca gaaggaacca aacctcgtaa ggtattgcaa
    15541 acaaactaaa agaacctgac gtctcatgat gagatgtcag gttctttttt tgtgatgtca
    15601 ggccagttga tgagatgcct atgctaatgt aaaaataaag ataactagaa taaggtagaa
    15661 aataacggtg actaaaaagc caactcgcca aaatagcttc ataaagcgat ggtaagaaaa
    15721 cgactgagtt cggatgacta gcagtagtga aatgacgatg gctagcagcg acatgataat
    15781 aaggtaataa ggcagtaaat tatgggtgaa aaattttcct gagacaagca caatttctac
    15841 cgcaaaaagt aaaagtgcga tatctggaaa tttaaatcct tttttattaa gtttaaataa
    15901 agaggttaca atcatggcaa aaagaggcgt tactatcaag aaagctaagg cagttaattt
    15961 atagatcatc ataggtctat tttatactca aatcccttac ttgtaaactg atacttacct
    16021 gttgtgatag aaaatgatct ttgagaggga aagcgcctac ttcaatttaa acattgcaaa
    16081 aggcatcagc tatttta
//
LOCUS       DAUGOH010000033        16039 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUGOH010000033 DAUGOH010000000
VERSION     DAUGOH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16039
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.033"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            5..78
                     /locus_tag="VH957_001277"
     tRNA            5..78
                     /locus_tag="VH957_001277"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            158..231
                     /locus_tag="VH957_001278"
     tRNA            158..231
                     /locus_tag="VH957_001278"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:192..194,aa:Arg,seq:acg)
     gene            227..808
                     /locus_tag="VH957_001279"
     CDS             227..808
                     /locus_tag="VH957_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ8559188.1"
                     /translation="MHNEKNNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYL
                     KDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQER
                     MQFQALIRGERFKGRRALLRKISPYFKEFAQQL"
     gene            995..1744
                     /gene="truA"
                     /locus_tag="VH957_001280"
     CDS             995..1744
                     /gene="truA"
                     /locus_tag="VH957_001280"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEQ8559189.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            1734..2498
                     /locus_tag="VH957_001281"
     CDS             1734..2498
                     /locus_tag="VH957_001281"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEQ8559190.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIISLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            2488..2958
                     /locus_tag="VH957_001282"
     CDS             2488..2958
                     /locus_tag="VH957_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8559191.1"
                     /translation="MQNSKIRQMSLTGILTALIVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGLKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            2972..3532
                     /locus_tag="VH957_001283"
     CDS             2972..3532
                     /locus_tag="VH957_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEQ8559192.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERYVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQFMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(3597..4442)
                     /locus_tag="VH957_001284"
     CDS             complement(3597..4442)
                     /locus_tag="VH957_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEQ8559193.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            4763..6046
                     /locus_tag="VH957_001285"
     CDS             4763..6046
                     /locus_tag="VH957_001285"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEQ8559194.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDTSKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            6263..6838
                     /locus_tag="VH957_001286"
     CDS             6263..6838
                     /locus_tag="VH957_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEQ8559195.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEVEEDEEPVL"
     gene            7095..8699
                     /locus_tag="VH957_001287"
     CDS             7095..8699
                     /locus_tag="VH957_001287"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEQ8559196.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            8867..9793
                     /locus_tag="VH957_001288"
     CDS             8867..9793
                     /locus_tag="VH957_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8559197.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLINRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIRENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            9847..9932
                     /locus_tag="VH957_001289"
     tRNA            9847..9932
                     /locus_tag="VH957_001289"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9881..9883,aa:Leu,seq:aag)
     gene            10140..11021
                     /locus_tag="VH957_001290"
     CDS             10140..11021
                     /locus_tag="VH957_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEQ8559198.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            11403..11591
                     /locus_tag="VH957_001291"
     CDS             11403..11591
                     /locus_tag="VH957_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEQ8559199.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            11743..12108
                     /locus_tag="VH957_001292"
     CDS             11743..12108
                     /locus_tag="VH957_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8559200.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            12108..13772
                     /locus_tag="VH957_001293"
     CDS             12108..13772
                     /locus_tag="VH957_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEQ8559201.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKTKA
                     EAKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            14009..14899
                     /locus_tag="VH957_001294"
     CDS             14009..14899
                     /locus_tag="VH957_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEQ8559202.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            15129..15983
                     /locus_tag="VH957_001295"
     CDS             15129..15983
                     /locus_tag="VH957_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEQ8559203.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
BASE COUNT         5263 a         2544 c         3467 g         4765 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gaaagaggta ggaagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggtaagatag aggcaatata tgcgttggca cccttagctc aactggatag
      181 agtacctgac tacgaatcag gcggttagag gttcgactcc tctagggtgc ataatgaaaa
      241 aaacaatagg acattagtgt cctgttgttt ttttgtggtt ctctttatac tagggatagt
      301 taaaaagaaa aggagactca aaatgtcgat agagacaaga gcagcgtttg aaaaagttaa
      361 gcccattatt ttgaaattaa agcgacacta ttatattcaa ttgtgggata gagatgactg
      421 gttacaagaa ggacatatta tcttattaca gttactagaa aggtacccag agttaattga
      481 ggaagaagag cgtttatatc gctattttaa aacaaaattt tcatcttatt tgaaagattt
      541 attacgccgt caagaaagtc aaaagcgtca gttccataag ttagcatatg aagagatagg
      601 ggaggttgca catgccattc catcgagagg gttatggcta gacgactatg tggcttatca
      661 agaggtaata gctagcttag agaaccaatt aaattcgcaa gagcgtatgc agtttcaagc
      721 acttatcagg ggcgaacgtt tcaagggaag acgtgctcta cttaggaaga tcagtcccta
      781 ttttaaggaa tttgcacagc agttgtaagc aagacctata aggaattggg ggtaaatcta
      841 taaaaaaagg agagagagtt tggaggaaat agctttctta tagcttttaa atcgttagta
      901 gcttagagta agcttcaata cgtctttcat ttgtttgggt acagtttgat taaaaatagt
      961 ttctcttacg tttaagaaat gttaaaatag taacatggta agatacaaag caacgatttc
     1021 ctatgatggg actctttttt cgggttttca aagacaaaga catttacgta cggttcaaga
     1081 agagattgaa aaaacactct ataaattaaa taacggtaca aaaattataa ttcatggtgc
     1141 aggacgtacg gatgcaggag tacatgctta tggacaggtg atccattttg atttgcctca
     1201 agaacaagaa gttgaaaaat tacgatttgc tcttgataca cagactcctg aagatattga
     1261 tgttgttaat atagaaaaag tggctgatga ttttcattgt cgttatcaga agcatttaaa
     1321 aacttatgaa tttttagttg ataatggtcg acctaaaaat ccgatgatgc gacactatac
     1381 cactcattac ccttatactc ttaatattaa acttatgcaa gaagctatta acggtctggt
     1441 aggtacacac gattttactg gttttacagc agcaggaact tcggtacaaa ataaggtgcg
     1501 aacgattacc aaagcaacgg tatctcggga tgaaaaaact gattttttgg tgtttacttt
     1561 ttcaggaaat ggttttctct ataagcaggt gaggaatatg gtgggaactt tgctgaaaat
     1621 tggtaatggt caaatgccag ttgaacaagt taaagtgatt ttgagctcca aaaatcgtca
     1681 gctagctgga ccaacgatat ctggaaatgg gctttacttg aaggagattt gttatgaaaa
     1741 ctgattatat cgtgactata tctgggaacg atattttaag tggaggtggt ctctatgctg
     1801 atttagcgac ttacataagg tatgacctac aggcctttgt ggcagtaact tgtttaacta
     1861 ctagatctga agagggcttt agtctatttc cggtagctaa agaaattttc cgtgatcagt
     1921 tgaacagctt tacgaacgct ccaatttctg ctattaaaat tggtttgtta cctaatgcgg
     1981 aaatgtgtga aatagttttg gattttataa aggggcatct gggaatccca gtggttttag
     2041 atcctgttct agcatgtaaa gaaatagatg atgttaaaat agttccttta agacaggaga
     2101 ttttacaatt actgccttat gtaactgttg ttactccaaa tttggtagag gctcagctat
     2161 tatctcaaaa agagattatt tctttaaaag atatgcaaga agctgctaaa tatttttatc
     2221 aacttggggc aaaacaggtg gttatcaagg gtggtaatcg atttagtcag aaaaaggcta
     2281 ttgatctttt ttatgacggt aaagagattg ttaccttgga atgtcctgta cttgagaaaa
     2341 ataatattgg tgcaggctgt acttttgcat ctagtatcgc tagtcagtta gtaaagaaaa
     2401 aaacgccact agaagctgtg aaaaactcaa aagagttagt ctatcaagct attttacaat
     2461 ctgatagata cggagtaaaa caaagttatg caaaatagta agatacgaca aatgagttta
     2521 acagggatat tgacagcatt gattgttgtt ttaggaagat ttgtcatgct acctactcca
     2581 acaggttttt taacgctgtt ggatgcagga atttatgctg tcagcttttc ctttggatca
     2641 gctcaaggag ctattgtggg agggttatca ggttttttaa tcgatttagt ggcaggatac
     2701 cctcagtgga tgtttcatag tttgattgct cacagtgtcc aagggtattt tgcgggatgg
     2761 agagggctca agcgttggct tggtgttgtg ataggttctt ttatcatgat tttttggtac
     2821 tttttaggct ctcttatgct tggttatggc ctttcgggat ctttagccgg tatttgggga
     2881 aacgtcatgc aaaatacatt agggcttttt gttggtttta ttatctttaa ggccatatta
     2941 aggcaaaaaa agagataagg agagtgagaa gttgttgaat aatttagaga aacaaacaag
     3001 ggaaatcgtc attgatgttg tagaacgctc tgctattcaa ccaggtaatc tttttgttct
     3061 aggtctttca tctagcgaaa ttttgggtag tagaattgga aaacaatcta gtctagaagt
     3121 aggtcaaata gttgttgaag ttgtgttaga tgaattaaat aagcgtggtg ttcatttggc
     3181 tgtacaaggt tgtgaacacg tcaatcgtgc cttggtagta gagaggtatg tggcagaatc
     3241 taagcagtta gagattgtca atgtggttcc gaatcttcat gctggtggca gtgctcagat
     3301 ggctgctttt caatttatgt cagaccctgt cgaagtagaa gaagttattg cacacgctgg
     3361 acttgatata ggtgatactg ctataggaat gcatattaag cgtgttcaga tccctctgat
     3421 tccttgtcaa cgagagctag gaggtgctca tgtgacagct ttggctagtc gaccaaaatt
     3481 aattggtgga gctagggctg attacaatat ggatattatc cgtaaatcct aaaccctttt
     3541 ttctggaata aaacaattgg tgttttttct agaaaaaagg attttttaag attatattaa
     3601 gattttgagg tgatagaata gctgattgca gtcggtaatt gaatgccttc tttgagtaaa
     3661 gcttcttgat aaagtctata aaaagtatgg taaatcttaa attgttctcc attttctgtg
     3721 aaaatagcaa ttctaaaagt gaactgtcca ttagagttat tttgaggccc taaaatattt
     3781 ggtttgccaa cgatttgagg atggtttggc aattcctttt gattcacttc atcaatgatt
     3841 cgagtgactt ggctcaaatt aacagtggaa taaagaggaa tttcaattaa ggcacgcata
     3901 ttaccacgag atttgttgct gacaacggtg atgctacggt ttgggatgaa atgtagtgtt
     3961 ccatcgaatc cacgaatttg agtagttcta attccaacac caaagacact gccttctatg
     4021 tcagagatag taacgttatc tcctacttca aattgattct caaataagat aaaaaagcca
     4081 ttgacaacgt cagataaaaa tccctgtgca cctaacccga ttgctactcc agcaattcca
     4141 gctcctgcta aaagactaga gacaggtatg ccaaataagc taagtatcca ataaatgaga
     4201 agaaaatata ataagtaatt taaaatgttg tgagtgagct tagagagtgt ttttttgcga
     4261 gcttcacttt gtcttgaata agcaaacgat ttgttaatgg ttttttcaaa aagatagtta
     4321 gtaacacgtt ttaaaatagc aaaaaagagt aatagaataa tgagagacac tagcttttta
     4381 aaaatcgtta agccaatatt ttcgatatga gactgctcta ggtaatgtaa tataaatgtc
     4441 atgagaaatc ctttctttga tagtttatca aaaaaaaacc aatcttgaaa agagataaat
     4501 taatatttta accaaagtta tgataattgt tttatcataa agaatgccat agtcatccgt
     4561 tgtgataatg cttgaaaata gtcagttagt aagcgaaaaa gtctaacatt aacctttata
     4621 aattgaaaat aactgttagt agactaatga caggtagata ctcttaatag cgcgtttgat
     4681 ttcacgcata aaaagcttta aaaacgcttt aaattatgat aaaatgaact gtatcgaaat
     4741 tattttaagg agaaatgact taatgtctac atcatttgaa aacaaagcta caaatcgtgg
     4801 cgtgattaca tttacaatca gtcaagataa aataaaacca gctcttgata aagcttttaa
     4861 taaaatcaaa aaagacttga atgcaccagg tttccgtaaa ggacacatgc ctcgtccagt
     4921 cttcaaccaa aaatttggtg aagaagttct ttatgaagat gctttgaata ttgtattgcc
     4981 agaagcttat gaagcagctg tgacggaact tggtcttgat gtggttgcac aaccaaaaat
     5041 cgacgttgtg tcaatggaaa aagggaaaga gtggacactt tctgctgaag ttgtgacaaa
     5101 acctgaagtg aaacttggtg attacaaaaa ccttgttgta gaagttgata cttcaaaaga
     5161 agtttcagat gaagacgtgg atgctaaaat tgagcgcgaa cgtcaaaacc ttgcggaact
     5221 cattattaaa gacggtgaag cagctcaagg tgacactgtt gtgattgact ttgttggttc
     5281 agttgatggt gttgagtttg atggcggtaa aggagataac ttctctcttg aacttggttc
     5341 aggacaattt atcccaggtt ttgaagatca actagttggt gctaaagctg gcgatgaagt
     5401 agaagttaat gtcacattcc cagaatctta ccaagcagaa gatcttgcag gtaaagccgc
     5461 taaatttatg acaactattc acgaagtcaa aacaaaagaa gtaccagagc ttgatgatga
     5521 gcttgcaaaa gatattgatg aagatgttga cacacttgaa gacttaaaag taaaatatcg
     5581 taaagaactt gaagcagctc aagaaactgc ttatgatgat gctgttgaag gagctgcgat
     5641 tgaactagca gttgcaaatg ctgaaattgt tgatttaccc gaagaaatga ttcatgaaga
     5701 agtcaaccgt tcagtgaatg agtttatggg caacatgcaa cgtcaaggaa tctcacctga
     5761 aatgtacttc caattgactg gtacaactca agaagattta cataaccaat attctgctga
     5821 agctgacaaa cgtgttaaaa caaaccttgt tattgaagca attgctaaag cagaaggttt
     5881 tgaagcaaca gatagtgaaa ttgaacaaga aattaatgac cttgcaacag aatataacat
     5941 gccagctgac caagttcgtt ctcttctttc agcagatatg ttgaaacatg atattgcaat
     6001 gaaaaaagca gttgaagtga ttacaagcac agcaagcgtt aagtaatctt attaaggaac
     6061 aaaacgtaca agccggatta gaacgtcttt ctagtctggt ttttcttttt ctaaagaaat
     6121 aataaggaat tagttaaacg ttattttaat gaattagctt taaagatttg tcaagaagaa
     6181 gtgatatgag ttgataaaag ttttgacgaa ttactttttt tagcgtaaaa tggtagagaa
     6241 tgataaaata aggagaactg ccttgaaatt agacgtattt gcaggacaag aaaaaagcga
     6301 gctttccatg attgaagtgg cgcgtgccat tttggaagaa cgcggtcgcg acaatgagat
     6361 gtactttagc gatttagtca atgagattca aaattactta ggaaaatctg atgcaggtat
     6421 tcgtcatgca ttaccatttt tctatactga cttaaatacg gatggctcat ttattcctct
     6481 aggtgaaaac aaatggggac ttcgttcgtg gtatgctatt gatgaaattg atgaagaaat
     6541 tattactcta gaagaagatg aagatggcgc acaaaaacgt aagaaaaaac gcgttaatgc
     6601 tttcatggat ggagatgaag acgctattga ttatagagat gatgatccag aagatgaaga
     6661 tttcacagaa gaatcagctg aggttgaata tgatgaagaa gatccagatg atgaaaaatc
     6721 agaagtggag tcatatgatt cagaattgaa tgaaattatc cctgaagatg attttgaaga
     6781 agttgatatc aatgaagaag acgaagaagt tgaagaagat gaagaaccag ttctctaatg
     6841 tctttagttc agaaataaaa atgtaattat catttgacaa attgtctatt atagtttata
     6901 ttattattcg ggcacctctt tatgaggtca ggcaaaagct ctctagttaa tagggggcta
     6961 tttttgtttt ctagaataat gccagtttgc ctctatattt agaaaactaa ggtgatacct
     7021 aaccaatgtg gaaccaacta atagggaatt aacaagaaag caatgctttt attcagctta
     7081 tataaaggag tactatgacg aaatacattt ttgtaactgg tggtgttgtg tcatcaattg
     7141 gcaaaggaat tgttgcggca agtcttggcc gattgttaaa aaatcgtgga cttaaggtga
     7201 cgattcaaaa atttgatcct tatattaata ttgatccagg gacgatgagc ccctatcagc
     7261 atggagaagt atatgtgaca gatgacggtg ctgaaaccga cttggatttg ggtcactatg
     7321 aacgttttat tgatatcaat cttaataaat attccaatgt tacaacaggt aaaatttata
     7381 gtgaagtcct tcgtaaagaa cgtaaaggcg agtaccttgg agcgactgtt caggtgattc
     7441 ctcatatcac agatgccctt aaagaaaaaa tcaaacgcgc agcttcaaca acggactctg
     7501 atgtaattat tactgaggtc ggggggactg ttggcgatat tgaaagttta ccgttcttag
     7561 aagctcttcg tcagatgaaa gctgatgttg gttctgaaaa tgtgatgtat attcacacca
     7621 ccttgttgcc atatttaaag gcagcgggtg aaatgaaaac taagccaacg caacattccg
     7681 ttaaagaatt gcgtggttta gggattcaac cgaatatgtt ggttattcgt acggaagagc
     7741 cagttgagca ggggattaaa aataaattgg ctcagttctg tgatgtgaat tcagaagctg
     7801 ttatcgagtc acgtgatgta gaacacttgt atcaaattcc attgaacttg caagctcaat
     7861 caatggatca gattgtttgt gatcatttga aattgaatgc gccacaagct gatatgaccg
     7921 agtggtcagc tatggttgac aaggtgatga atttaagaaa aacaacaaaa attgccttgg
     7981 ttggtaaata tgtggaattg ccagatgcct acttatctgt tgtggaagcc ttgaaacatt
     8041 ctggttatgc caatgatacc gcaattgacc taaaatgggt caatgctaac gatgtgacgg
     8101 tggataatgc agctgacttg ttgggagatg cggatgggat tattgtacca ggtggttttg
     8161 gtcaacgtgg tacagaaggc aagatccaag cgattcgcta tgcccgcgag aatgatgtgc
     8221 caatgcttgg tatctgtctt ggcatgcagt tgacttgtgt tgaatttgct cgccatgtcc
     8281 tcaatatgga aggtgcaaac tcttttgaat tagagccaag tactaaatac cccatcattg
     8341 atatcatgcg tgatcaaatt gatattgaag atatgggagg tacgcttcgt ctgggattgt
     8401 acccatgtaa attgaaacca ggttcaaaag cagcaatggc ttacaataat caagaggtgg
     8461 tgcaacgtcg tcatcgtcac cgttatgagt tcaacaacaa attccgtcca gaatttgaag
     8521 cagctggttt tgttttctca ggggtatcac ctgacaatcg cttagttgaa attgtagaat
     8581 tgaaagagaa aaaattcttt gtagcagctc aataccaccc agaattgcaa agccgtccaa
     8641 atcgtcctga ggagctatac accgcttttg ttacagctgc tattaaaaat agcaattagt
     8701 ggttttaagg gtaagtttgt ggcattctac ttggctggca gatactgata aagattacta
     8761 gctattaaag ggatcttttc tataaaaata gcattagaaa aagaaaaacg tgatattttt
     8821 aggttagcac tttctttttc agtcattttt ttgtaaaata cttggtatga aaactattcg
     8881 aatagcaaag tatttaggaa ttctattcct tttgataact cttattagcg taggtgctag
     8941 tttttatttc tttcatgttg cacaaataag agaagagaaa tcgtttatta ataataagaa
     9001 acggagtaca aataatccat tatacccagc tgaacagtct tttgacgctt taccttacga
     9061 aaaacgtcaa ctaataaatc gtgggttaaa acaagtgggg tggtacttac cagctgctca
     9121 aaaaacaaaa aagacagcta ttgttgttca tggttttacg aatgacaaag aagatatgaa
     9181 gccatatgcc atgctttttc atgatttggg ctataatgtc ttaatgccag acaatgaggc
     9241 ccatggggaa agtgaaggga acttgattgg ttatggctgg aatgaccgcc ttaatgtcat
     9301 ggcttggaca gaccaactga ttagggaaaa ccctgaaagc caaatcacac tctttggctt
     9361 atctatgggt gctgcaacag taatgatggc aagtggtgag cgattgcctg cgcaagtcac
     9421 ctccctcatc gaagattgcg gttataccag tgtttgggac gaattgaagt ttcaggccaa
     9481 ggctatgtac aacttgcctg cctttccttt actctatgaa gtctctgcct tatctaagat
     9541 tcgagcaggt tttagttacg gagaagcgag ctcagtgaaa cagctggcta aaaataaacg
     9601 tccaacttta tttatccatg gtgataagga tgattttgtt cctacaaaaa tggtttatga
     9661 caattataag gccacgaaag gtcctaagga aatcttgatt gttaaagggg caaaacacgc
     9721 caaatccttt gaaacaaacc cagaacaata ccagaaaaaa attgccgctt ttttgaaaaa
     9781 agttgagaaa taagtattga cagttaaact cacagttgct ataatgattt atgttactga
     9841 tgagtagcgg ggatggcgga attggcagac gcgcaggact aaggatcctg tgaccgcttt
     9901 aggtcgtgtg ggttcaagtc ccactctccg cataatgtaa gaggtgaatc attgattcgt
     9961 ctctttttgt ttggttaaat gaaggataag aaggcataga tttaccggag aaaacttttg
    10021 ataatctgct tttggaaaac gctttaagct tgtgaaagac tagaaattta tggaaaattg
    10081 tgctagaatg aacaatgtaa acggggagtt atcccgaaaa ataagaggag gccttacaaa
    10141 tggcaatcgt ttcagcagaa aaatttgtcc aagcagctcg tgaaaacgga tatgctgttg
    10201 gtggatttaa cacaaacaac ttagagtgga ctcaagcaat cttgcgtgca gcagaagcta
    10261 aacaagctcc agttcttatc caaacatcaa tgggtgcagc aaaatacatg ggtggttata
    10321 aagtatgtca atctcttatt actaaccttg ttgagtcaat gggtatcact gttcctgttg
    10381 ctatccacct tgatcatggt cactacgaag atgctcttga gtgtatcgaa gtaggttaca
    10441 cttcaatcat gtttgacggt tcacaccttc cagttgaaga aaaccttgct aaaactgcag
    10501 aagttgttaa aattgcacat gctaaaggcg tttcagttga agctgaagtt ggtacaatcg
    10561 gtggtgaaga agacggtatc atcggtaaag gtgagctcgc tccaatcgaa gatgctaaag
    10621 caatggttga aactggaatt gacttcttgg cagctggtat cggtaacatc cacggtccat
    10681 acccagaaaa ctgggaaggt cttgctcttg accacttaga aaaattaaca gcagctgtac
    10741 caggtttccc aatcgtattg cacggtggtt ctggtattcc tgacgatcaa atcaaagaag
    10801 caatccgtct tggtgttgct aaagttaacg ttaacactga aagtcaaatc gctttctcta
    10861 acgcaactcg tgaatttgct cgtaactacg aagctaacga agcagaatat gatggtaaaa
    10921 aattatttga cccacgtaaa ttcttggctc caggtatgaa agctgttcaa ggtgctgttg
    10981 aagaacgtat cgatgttttc ggatcagcta acaaagcata atttagagta ttaaataccc
    11041 taaagccctc ttgagggctt ttttagatac aattgacatc ttaaaatgga taccagtttc
    11101 tgtgaaacaa tctttgattg tgaacaaaca aagcataatt tagagtatta aaatttggac
    11161 cctgctatct atggtaaatc tttttgttat tgttaaagag gttaagcgga atgttaatat
    11221 gttttagcta aaaaatgtag tgaaaaatga gtacgtagac tattgtaata gtaattccgt
    11281 aaaattgttg aaaaagaaaa tgggaaatac cttgtcaaat taagcaccct atgatagaat
    11341 agataggtat gtggtgctag cacatccgta aacatattct acgtaggagg aaacagatca
    11401 aaatggctaa agtatgttat tttacaggac gtaaaaccgt ttctggaaac aaccgttcac
    11461 acgcgatgaa ccaaacgaaa cgtacagtta aaccaaacct tcaaaaagtt actatccttg
    11521 ttgatggtaa acctaaaaaa gtttgggctt ctgctcgtgc gcttaaatct ggtaaagtag
    11581 aacgcatcta atagaaataa gccttagggc tttttttatt agcttatttc tatccataag
    11641 ctagtcaggg taataaacgc tattgttaac tattctatct cttttacatt acttctaaaa
    11701 tatgataaaa taggatgata aaaacttttt gaggtagtaa ctatgactgt aaaaattaat
    11761 acaaaagatg gtctaatcga gctatccgac gatgtgattg caactgtcgt gggaggatca
    11821 gcaacggaaa tttttggtgt tgttggaatg gccagcaaaa gtgcaataaa agacaatttt
    11881 caatcactac ttcgcaaaga aaactacgct aagggtgttg tagtaaaatc aacagatctg
    11941 ggtatttctg ttgatgtcta cactgtgatg agttatggtg tgaaaatcag tgaagtctct
    12001 aaaaatatcc aagaacgcgt gaaatttaac cttgaaagtc agcttggtct cactgctgat
    12061 atggtcaatg tttacgtgca aaatattaag gttgtaggag aaaattagtg tcaaatatta
    12121 caacaagctt attccaagaa atggtccaag cggcagcgac tcgccttggc aaacaagcag
    12181 aatatgttaa ttccttaaat gtttttcctg ttccagatgg tgatacagga acaaacatga
    12241 gcatgactat ggacaatggt gccaaggaag ttgctgataa acctgcgtca actgtgggag
    12301 aagttggaca aatgttatca aaaggtcttt tgatgggagc gcgtggaaat tctggagtta
    12361 ttacttcaca actttttcgt ggttttggtc aaagtattaa gggaaaagat gagctgacag
    12421 gtaaagattt ggcacaagcc tttcaagtgg gtgtagaagt tgcctacaaa gcagtgatga
    12481 aacctgttga agggacaatc ttgacagtat ctcgtggagc agcaaccgct gccttaaaaa
    12541 aagcagatct tacagacgac gccgtggaag tcatgcaagc tgctttagac ggtgccaaag
    12601 gtgcccttgc taagacacct gatttattac cagtccttaa agaagttggt gtggttgatt
    12661 caggcggtca aggtcttgtc tttatctatg aaggtttcct atctgctttg aatggcgact
    12721 atgtgacttc agcagacttt aaagcgactc ctgctaacat gtctgaaatg attaatgctg
    12781 agcatcacaa atccgttgtt ggtcatgtgg ctactgaaga cattacctac ggttattgta
    12841 ctgaaatcat ggttgccctt aaacaaggcc caacctatgt gaaagaattc aactatgatg
    12901 agtttcaagg ctaccttagt ggccttggtg actcgctgtt agtggtcaat gatgatgaga
    12961 ttgttaaagt tcacgtccat actgaagacc ccggacttgt gatgcaagaa ggtcttaaat
    13021 atggttcgct catcaagatt aaagtggaca atatgcgtaa ccagcatgaa gcacaggttc
    13081 aaaagactga tgtcgaaaaa accaaggctg aagcaaaaga ctttggcttg attgcagtag
    13141 tagctggaga gggtttatct gaaattttca aggcgcaagg tgttgattac gtgatttctg
    13201 gtggtcaaac catgaatcca tctacagaag atattgttaa agctattgaa gcagttaatg
    13261 ccaaacaagt cattatcttg ccaaacaata aaaatatctt tatggctgcc caatctgctg
    13321 cagaagtggt ggatatcccg gctgctgttg ttgcaacacg tactgttccg caaggattta
    13381 ccagcttgtt ggcctttgat ccttcaaaat ctttagagga caatgtagca gatatgtcaa
    13441 ctagtctttc tgacgtggtc agtggaagcg ttactttggc agtccgtgac accaccattg
    13501 atggtttaga aatccatgaa aatgatttct tgggaatggt tgatggtaaa atcatcgttt
    13561 caaacccaga catggaagca actctaaaag ctgcctttga aaagatgatt gacgaagata
    13621 gcgagattgt gactatcttt gttggtgaag aaggtgatca agacttagca gaagaacttg
    13681 ctgggtattt aggagagact tacgaagatg tggaagttga gatccatcaa ggagatcagc
    13741 ctgtttaccc atatctcatg agtgtagaat aatagaatac aataaaaaaa gaggagttag
    13801 gcaaaggtct gactcttttt gtctatattg atgtcgtaat gagtggtttt agtgatggta
    13861 agcccctaaa aaatgagggt aatccatcac aaagctaatg gttacgattt aatttgacaa
    13921 aacctagaaa aacattataa ttgtattata acaataagtc aagaactgaa aacggttcag
    13981 ttctaagata tgacaaggag gagattttat gttaggacca tttatcttta ttgcttttgg
    14041 ggttattgta atcctagcta ttgttgccag taccctttat gttgttcgtc aacaatctgt
    14101 tgccatcgtg gaacgttttg gtaggtacca aaaaacagcc acgagtggta ttcatgtccg
    14161 ccttccgttt gggattgaca aaattgctgc gcgtgtgcag ctgcgtcttt tacagtcaga
    14221 aatcatcgtt gaaaccaaaa ccaaggacaa tgtgtttgta actttgaatg ttgccactca
    14281 gtatcgtgtt aacgaacaaa atgtaacaga tgcttactac aaattaatga aacctgaatc
    14341 tcaaatcaag tcttatattg aagatgcctt gcggtcatcc gtgccgaagt tgaccttaga
    14401 cgaattgttt gagaaaaaag atgaaattgc cttggaagta caacatcaag tggcagaaga
    14461 aatgtcaacc tatggatata ttattgtcaa aaccttgatt accaaggtgg agcctgatgc
    14521 tgaagtcaaa cagtcaatga atgaaatcaa tgcggctcaa cgcaaacgtg tagctgctca
    14581 agagttggca aacgcagata aaattaaaat tgtgacagca gcagaagctg aggctgaaaa
    14641 agatcgattg cacggggtag ggattgccca acagcgtaag gccattgtgg atggtttggc
    14701 ggagtctatt caagagctta aagaagcgaa tatttcctta aacgaagaac aaatcatgtc
    14761 cattttgttg accaaccaat acctggatac cctcaatacc tttgcggcaa aaggaaacca
    14821 aacccttttt ctaccaaata caccaagtgg agtagaggat atccgtacac aagttttatc
    14881 tgcccttaaa acaaaataac gtgtaaaagc ttggctaaaa agttgctcaa tactggattt
    14941 agcagaaggc tatcataact tgtgaagtgg caaacgacga aatgaataca ttacttttat
    15001 tggagaaatg aaagtaaaaa aagccttttt catgattaac aacatagtat tgattaaatg
    15061 ttaagttgta ttgactttta aattaaataa gtttaaaatc aatttaataa gcaaaaagga
    15121 gattttcaat gaaatccaaa aaagttgtta gtgttatatc acttacctta tccctttttt
    15181 tggtgacagg ttgtgctaaa gttgataaca acaaatcagt taatcgtaag cctgctacta
    15241 aacaaaccta taatagctat agtgatgacc aattaagatc gcgtgaaaat accatgtctg
    15301 ttttatggta ccagcgagct gcggaaactc aagcgcttta tttacagggg tatcagttag
    15361 caacggatcg cttaaaagaa caactcaata aaccaacgga taaaccttat tcaattgtat
    15421 tagatattga cgaaacagtt cttgataata gcccttatca agctaaaaat gttttggaag
    15481 gaacaggatt tacacctgaa agctgggatt attgggtaca aaagaaagaa gcaaaaccgg
    15541 ttgctggtgc taaagacttt ttgcaatttg cagaccaaaa tggtgttcaa atttactaca
    15601 tttcagacag atcaactact caagtagatg ctacaatgga aaatctccaa aaagaaggta
    15661 ttccagtaca aggtcgtgat catcttctat tcttagaaaa aggcgtaaaa tcaaaggaga
    15721 gtcgtcgtca aaaggtcaaa gaaacaacta atgtaacgat gctatttggt gataatcttc
    15781 tagattttgc tgatttttca aaaaaatctc aagaagatag aacagcttta ttatcagatt
    15841 tgcaagaaga gtttggaaga cgctttatca ttttccctaa tcctatgtat ggttcatggg
    15901 agggtgccat ttataaaggt gaaaagctgg atgtgcttaa gcaactagag gaacgccgta
    15961 aaagtttaaa aagctttaaa taaagtaatt gaaaaagagg tgcaaaagaa aatgtaacct
    16021 ctttttaagt actattatt
//
LOCUS       DAUGOH010000034        15876 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUGOH010000034 DAUGOH010000000
VERSION     DAUGOH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15876
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.034"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(210..973)
                     /locus_tag="VH957_001296"
                     /pseudo
     CDS             complement(210..973)
                     /locus_tag="VH957_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1138..1211
                     /locus_tag="VH957_001297"
     tRNA            1138..1211
                     /locus_tag="VH957_001297"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1172..1174,aa:Arg,seq:tct)
     gene            complement(1368..1847)
                     /gene="rlmH"
                     /locus_tag="VH957_001298"
     CDS             complement(1368..1847)
                     /gene="rlmH"
                     /locus_tag="VH957_001298"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEQ8559204.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIDLTDERTP
                     DKASDAENQMIMAKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            2059..3282
                     /locus_tag="VH957_001299"
     CDS             2059..3282
                     /locus_tag="VH957_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEQ8559205.1"
                     /translation="MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            3341..4147
                     /locus_tag="VH957_001300"
     CDS             3341..4147
                     /locus_tag="VH957_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEQ8559206.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIITNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            4380..5735
                     /gene="dnaA"
                     /locus_tag="VH957_001301"
     CDS             4380..5735
                     /gene="dnaA"
                     /locus_tag="VH957_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEQ8559207.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            5890..7026
                     /gene="dnaN"
                     /locus_tag="VH957_001302"
     CDS             5890..7026
                     /gene="dnaN"
                     /locus_tag="VH957_001302"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ8559208.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            7101..7298
                     /locus_tag="VH957_001303"
     CDS             7101..7298
                     /locus_tag="VH957_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEQ8559209.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            7628..8743
                     /gene="ychF"
                     /locus_tag="VH957_001304"
     CDS             7628..8743
                     /gene="ychF"
                     /locus_tag="VH957_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEQ8559210.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            8813..9382
                     /locus_tag="VH957_001305"
     CDS             8813..9382
                     /locus_tag="VH957_001305"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEQ8559211.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            9385..12888
                     /gene="mfd"
                     /locus_tag="VH957_001306"
     CDS             9385..12888
                     /gene="mfd"
                     /locus_tag="VH957_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEQ8559212.1"
                     /translation="MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GISINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLVVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFTDNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQISSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVTRQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYISDERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            13050..13322
                     /locus_tag="VH957_001307"
     CDS             13050..13322
                     /locus_tag="VH957_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEQ8559213.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            13309..13680
                     /locus_tag="VH957_001308"
     CDS             13309..13680
                     /locus_tag="VH957_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEQ8559214.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKRTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            13815..15101
                     /locus_tag="VH957_001309"
     CDS             13815..15101
                     /locus_tag="VH957_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEQ8559215.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPVGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFCSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            15098..>15876
                     /gene="tilS"
                     /locus_tag="VH957_001310"
     CDS             15098..>15876
                     /gene="tilS"
                     /locus_tag="VH957_001310"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8559216.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLTIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDL"
BASE COUNT         5497 a         2509 c         2829 g         5041 t
ORIGIN      
        1 ttgaccaacg gaccagaagt tttggaggat atctccttaa cactcttact attatagcag
       61 attgattttt tttgtctata ctttttttaa aaaaaatttg atttttttta aaccgcaagt
      121 tgtcaagtca agtgcaacga gttcatagat aactagagtt ccagaggtta agctgttcgg
      181 gatagctcaa acaggaattt tgaggattgc tattgaagaa gtcgtcttag gcgctcattg
      241 atggcagtaa tatcattgtc aagttcttca gaggttagtg gattaagtga gattccttta
      301 gggacatatt ctctgaggag gccattgaag ttctcgtttg ttcctctctc atgtgaagaa
      361 tagggatgtg caaagtaaac gtcaacagct tctaagtctg agagtaaact aaactcagaa
      421 ccattatccg ctgtgatgga tgcaatagga tactgactga tgagatgcgt gacagcacgg
      481 ttaatggttt gggactgctt gtcttctagc ttaactccta gtgcatagcg tgtctggcgc
      541 tctaccaaag tcaacataac agcttcacct ttggttttct tgccgagaac caaatcaatc
      601 tcccaatgcc caaattcaga acgatcatta atatattctg gacgttcttc gatagattta
      661 cctaaagtct tcttattcgt cttcatgact ttcttagaac gttttctgat actaaccatc
      721 ttagacaaat cgattggttt aatagactat cagcgaaata ggcgttgaag aaggtttgtt
      781 ttccattctt atcctttacc tgatctactg aaccacgttt tatttctcgg cagattgtag
      841 aacagtgacg ccccagaagt cgagcaatct caacgggttt ctttcccatt ttaagataag
      901 cagcaatttc accccgttct gtggctgaaa gatgagaata ggaggatttt ctggtagaat
      961 taatattaga catgttcatc tgctttccat actgaattgg ggaattctag tatatcagac
     1021 gaacatgtct tttttgttgt acttcatttt ataacgcggg atataatgtt attttctagt
     1081 ttttttaaaa taaatattga cagttttaga taatttttgt taaaatgatg tggttaaggt
     1141 ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag gttcgaatcc
     1201 tgctgggatc aaagataaaa aagcactgtt ttagtgcttt ttttgtattt accttagtgt
     1261 attgaaaaga taggatttag tctgtctttt tttaatattt gcttttaatt ataccaaact
     1321 attatctaat aaagtggtaa gagttagtta ttccagttca cactctctta cttatgataa
     1381 ggactgcctt gtgtaatcat aaaagcacga taaatttgct cagtaaggac tagacgcatt
     1441 aactgatgag gtaaggttaa caatccaaaa ctcattagca tattagctct ttttttaata
     1501 attgaatcta atccaagact cccaccaata ataaacgtga tagttgaata tcccttaaca
     1561 gtaacccctg atattaattc actaaatgtc tctgaaggaa actgttttcc ttcaatagct
     1621 aatgcaatta caaaatcacg ttccccaatt tttttatgga ttcgctgagc ttccttagcc
     1681 atgatcattt ggttctcagc atcacttgct ttatctggtg ttctttcatc agttaaatca
     1741 atcatttcga attgacaaaa acgggaaagt cttttttgat attctgaaat accatctttg
     1801 aggtatcttt cttttagttt tccaacacaa attagtttta ctttcatagc ttaattgtat
     1861 cacaagaaca ttacttttta cacaatttat ccacaagtta tttttcttca actactaata
     1921 aaaacctttg tacaaaggtc tttattagta aaaagaaaag taatccacag cctgtggatt
     1981 acttttcttt tttttatttt taaggtataa ttaagcaaag ttctataagc tatggacaaa
     2041 taattcggag gacaaaacat gccaagtatg aaacatatct taaaatcctt aagtatttta
     2101 ctaattggat ttttaggagg attaatagca attattacat tcaataatct ctacccacat
     2161 tctccttcaa aaataaattc aggtaaggca acaactagta atatggtttt taacaacaca
     2221 accaatacta ctaaagctgt caaagctgtt caaaatgcag ttgtatcagt tattaattat
     2281 caagataacc cttcttcatc cctttctaac ccttatacaa aactctttgg agaagggcgt
     2341 tcaaaagaga ataaggatgc tgaattatct atttttagtg aaggatctgg ggtcatttat
     2401 cgaaaagatg gcaactccgc ttacgttgtt actaataacc atgttatcga cggagctaaa
     2461 cggattgaaa ttcttatggc agacggatct aaagttgttg gtgaattagt tggagctgat
     2521 acttattcgg atttagctgt tgttaagatc tcttcagata agataaaaac agtagctgaa
     2581 tttgcagact ctacaaaact aaatgttgga gaagttgcta ttgctatcgg cagcccacta
     2641 ggaacacaat acgctaattc tgttactcaa ggaatcgtct ctagtttaag tcgtactgta
     2701 actttaaaaa acgagaatgg tgagactgtc tcaacaaatg ctattcagac agatgctgct
     2761 attaaccctg gaaactctgg tggaccacta attaatattg aggggcaagt aatcggaatt
     2821 aattcaagta aaatttcttc taccccaact ggtagcaacg gtaatagtgg tgctgttgaa
     2881 ggaattggtt ttgctatccc atctactgac gttattaaaa ttattaaaca actagaaact
     2941 aatggtgaag ttattagacc tgctcttgga atatccatgg tcaatttaaa tgacttatcc
     3001 acaaatgctc ttagccaaat taatattcca actagtgtaa ctggtggtat tgtagtagca
     3061 gaggttaagg aaggaatgcc ggcatctggc aaacttgctc agtacgatgt gattacagaa
     3121 attgatggca aaacagttaa ttcaattagt gatttacaaa gtagtctata cggacacgat
     3181 attaatgata ctattaaagt aactttttat agaggaacta caaagaaaaa agcagatatc
     3241 aaattaacaa aaactactca agatttgact aaaacgcagt aaacaagcta cctaaatact
     3301 attacatttt atcacataaa acagtccaaa ggactgtttt atgtttctta ttctatccag
     3361 gaactccctt atgacaaaag aattattgat agacttacca attgaagata ttattacaaa
     3421 tccctatcag ccaaggatac aatttaatca aagagaactc caagacctag caacttctat
     3481 taaatcaaac ggcctcattc aacctattat tgttcgaaaa tctgacattt ttggctatga
     3541 gttagttgct ggagaacgac gacttaaagc ttcaaaaatg gctggtctaa aaaaagttcc
     3601 agctatcatc aagaagatct ctacactcga gagcatgcaa caagctatag ttgaaaattt
     3661 acaacgttct aaccttaacg ctatcgaaga agctaaagcc tatcagttat tagttgaaaa
     3721 aaaacacatg actcacgatg agattgctaa atatatggga aaatcaagac cttatattag
     3781 caatacctta cgtctgttac aactcccagc accaatcatt aaagcaattg aagaaggaaa
     3841 aattagtgcg ggacacgcgc gtgctctttt aactttgagt gacgataagc aacaactgta
     3901 cctcactcat aaaatacaaa atgaaggcct aagtgttagg caaattgagc aactagttac
     3961 ttctactcca agttcgaagc tatctaaaaa aactaaaaat atttttgcca cttctttaga
     4021 gaaacaattg gctaaatcat tgggactctc tgtcaatatg aagctgacag caaaccatag
     4081 tgggtacctt cagatatctt tttccaatga tgatgaatta aacagaatta tcaacaagct
     4141 aaagtagctt gttgatattc tgttttttct tttttagttt tccacataaa aaatagttga
     4201 aaacaatagc ggtgtcacct taaaatggct tttccacagg ttgtggagaa cccaaattaa
     4261 cagtgttatt ttattttcca caggttgtgg aaaaactaac tattatccat tgttctgtgg
     4321 aaaactagaa tagtttatgg tagaatagtt ctagaattat ccacaagaag gaacctagta
     4381 tgactgaaaa tgaacaaatt ttttggaaca gggtcttgga attagctcag agtcaattaa
     4441 aacaggcaac ttatgaattt tttgttcatg atgcccgtct attaaaggtc gataagcata
     4501 ttgcaactat ttacttagat caaatgaaag aactcttttg ggaaaaaaat cttaaagatg
     4561 ttattcttac tgctggtttt gaagtttata acgctcaaat ttctgttgat tatgttttcg
     4621 aagaagacct aatgattgag caaaatcaga ccaaaatcaa tcaaaaacct aagcagcaag
     4681 ccttaaattc tttgcctact gttacttcag atttaaactc gaaatatagt tttgaaaact
     4741 ttattcaagg agatgaaaat cgttgggctg ttgctgcttc aatagcagta gctaatactc
     4801 ctggaactac ctataatcct ttgtttattt ggggtggccc tgggcttggg aaaacccatt
     4861 tattaaatgc tattggtaat tctgtactat tagaaaatcc aaatgctcga attaaatata
     4921 tcacagctga aaactttatt aatgagtttg ttatccatat tcgccttgat accatggatg
     4981 aattgaaaga aaaatttcgt aatttagatt tactccttat tgatgatatc caatctttag
     5041 ctaaaaaaac gctctctgga acacaagaag agttctttaa tacttttaat gcacttcata
     5101 ataataacaa acaaattgtc ctaacaagcg accgtacacc agatcatctc aatgatttag
     5161 aagatcgatt agttactcgt tttaaatggg gattaacagt caatatcaca cctcctgatt
     5221 ttgaaacacg agtggctatt ttgacaaata aaattcaaga atataacttt atttttcctc
     5281 aagataccat tgagtatttg gctggtcaat ttgattctaa tgtcagagat ttagaaggtg
     5341 ccttaaaaga tattagtctg gttgctaatt tcaaacaaat tgacacgatt actgttgaca
     5401 ttgctgccga agctattcgc gccagaaagc aagatggacc taaaatgaca gttattccca
     5461 tcgaagaaat tcaagcgcaa gttggaaaat tttacggtgt taccgtcaaa gaaattaaag
     5521 ctactaaacg aacacaaaat attgttttag caagacaagt agctatgttt ttagcacgtg
     5581 aaatgacaga taacagtctt cctaaaattg gaaaagaatt tggtggcaga gaccattcaa
     5641 cagtactcca tgcctataat aaaatcaaaa acatgatcag ccaggacgaa agccttagga
     5701 tcgaaattga aaccataaaa aacaaaatta aataacatgt ggaaaagaat atcttttatg
     5761 aaatagttat ccacaagttg tgaacaacca tttagtcttg gattctctcg tttatttaga
     5821 gttatccact atatacacaa gacctactac tactacttat tattatactt attaaataaa
     5881 ggagttctca tgattcaatt ttcaattaat cgcacattat ttattcatgc tttaaatgca
     5941 actaaacgtg ctattagcac taaaaatgcc attcctattc tttcatcaat aaaaattgaa
     6001 gtcacttcta caggagtaac tttaacaggg tctaacggtc aaatatcaat tgaaaacact
     6061 attcctgtaa gtaatgaaaa tgctggtttg ctaattacct ctccaggagc tattttatta
     6121 gaagctagtt tttttattaa tattatttca agtttgccag atattagtat aaatgttaaa
     6181 gaaattgaac aacaccaagt tgttttaacc agtggtaaat cagagattac cttaaaagga
     6241 aaagatgttg accagtatcc tcgtctacaa gaagtatcaa ccgaaaatcc tttgatttta
     6301 aaaacaaaat tattgaagtc tattattgct gaaacagctt ttgcagccag tttacaagaa
     6361 agtcgtccta ttttaacagg agttcatatt gtattaagca atcataaaga ttttaaagca
     6421 gtagcgactg actctcatcg tatgagccaa cgtttaatca ctttggacaa tacttcagca
     6481 gattttgatg tggttattcc aagtaaatct ttgagagaat tttcagcagt atttacagat
     6541 gatattgaga ccgttgaggt atttttctca ccaagccaaa tcttgttcag aagtgaacac
     6601 atttcttttt atacacgcct cttagaagga aattatcccg atacagaccg tttattaatg
     6661 acagaatttg agacggaggt tgttttcaat acccaatccc ttcgccacgc tatggaacgt
     6721 gccttcttga tttctaatgc tactcaaaat ggtactgtta agcttgagat tactcaaaat
     6781 catatttcag ctcatgttaa ctcacctgag gttggtaagg taaacgagga tttggatatt
     6841 gttagtcagt ctggtagtga tttaactatc agcttcaatc caacttacct tattgagtct
     6901 ttaaaagcta ttaaaagtga aacagtaaaa attcatttct tatcaccagt tcgaccattc
     6961 accctaacac caggcgatga ggaagaaagt tttatccaat taattacacc agtacgaaca
     7021 aactaagtaa gaaaaagctc ccttttagga gtttttttgt tattataaat attaacgata
     7081 atataagtgg agaaaaggga atgtatcaaa ttggatcatt tgttgaaatg aaaaaacctc
     7141 atgcttgtgt aattaaagaa actggtaaaa aggctaatca atggaaggta ctgagagtag
     7201 gagctgatat taaaattcag tgtactaact gtcagcatgt gattatgatg agtcgttatg
     7261 attttgagcg aaaattaaaa aaagtactgc aaccatgaaa gtccttttaa ataaataatt
     7321 ctagctatat ttgcaaccaa tactttccta aaaaattgct agtatgccgt tggaaaattc
     7381 gctattctaa tgttatcgaa agaagaaaga tggccattga caatgacgaa agttgtagca
     7441 cagttactta gtttctcggc aaactatatc aaaatgagaa taatacacca aactttgata
     7501 atttaaatga aggtgaaaga gtggcataat gataagcaaa tctgaaattt tcttcttatt
     7561 cataccgctt tttcttctat tttttggtat aataatcttg attgaaattt gaatggagat
     7621 tcgctaaatg gctttaacag caggtattgt aggcttacca aatgttggta aatcaacctt
     7681 atttaacgca attacaaaag caggagcaga agctgctaat tatccttttg cgactattga
     7741 tcccaatgtt ggtatggtag aggttccaga tgagcgtctg caaaaattga cagaattgat
     7801 tacacctaaa aaaacagttc cgacaacctt tgaatttact gatattgcag gtatcgttaa
     7861 aggtgcttct agaggggaag gtctaggaaa taaattttta gctaatattc gtgaagtcga
     7921 tgctattgtt catgtggtac gtgcttttga tgatgaaaat gtcatgcgtg aacaaggtcg
     7981 tgaggatgct ttcgttgatc ctatagcaga tattgacact attaatcttg aattaatctt
     8041 agctgattta gagtcaatca ataaacgtta tgcgcgtgtt gaaaaaatgg cacgaactca
     8101 aaaagataaa gaatcagtag cagagtttaa tgttttgcaa aagattaaac ctgttttgga
     8161 agatgggaaa tcagctagga caattgagtt tacagaagat gaagcaaaag ttgttaaagg
     8221 tctcttttta ttaacaacta aacctgtttt atatgtagct aatgtcgatg aagataaagt
     8281 tgctaatcca gatggtattg attatgtcaa acaaattcgt gactttgcag ctactgaaaa
     8341 tgctgaagta gttgttatct cagcgcgtgc agaagaagaa atttcagagc ttgacgatga
     8401 ggataaagaa gaatttttgg aagctatcgg tcttactgaa tcaggcgttg ataaattaac
     8461 cagagcagct tatcatctct taggccttgg aacctatttt acagcaggtg aaaaagaggt
     8521 tcgtgcttgg acgtttaagc gtggtataaa agctccacaa gctgctggta ttatccattc
     8581 agattttgaa agaggtttta ttcgtgcagt aaccatgtct tatgatgatc taatgaccta
     8641 cggttcagaa aaagccgtca aagaagctgg acgcttgcgt gaagaaggaa aagaatatgt
     8701 tgtccaagat ggggacatca tggaattcag atttaatgtg taattatatt aaaataatat
     8761 cagaaggttg gaagaacatt ccagcccttt tggcatttta gaaagagaaa atatggtaaa
     8821 aatgattgtt ggtctgggaa atccaggctc taaatatgaa aaaacaaagc acaatattgg
     8881 ttttatggct attgacaata ttgtcaagaa ccttgacgtt acctttacag atgataaaaa
     8941 ttttaaagca cagataggaa gtacttttat taatcatgaa aaagtttact ttgtgaaacc
     9001 tactactttt atgaataata gcggcatagc agtaaaagca ttactaacct actataatat
     9061 tgacataaca gatttaattg ttatctatga tgatttagac atggaagtca gtaaattacg
     9121 tttacgtagt aagggttcag caggaggaca taatggcatt aagtcaatca ttgcccacat
     9181 tggaactcag gaatttaacc gaatcaaagt tggtattgga cgacctttaa aaggtatgac
     9241 tgttattaac catgtgatgg gccaattcaa taccgaagat aatattgcta tttcgttaac
     9301 tcttgacaga gttgtcaatg ctgtcaagtt ttatttacaa gaaaatgatt ttgaaaaaac
     9361 aatgcagaaa tttaatggat aatcatgaat attttagaat tatttagtca gaataagaaa
     9421 gtccaatcct ggcactctgg attaaccacc ttaggaagac aactggtaat ggggttatcg
     9481 ggttcaagta aagcattggc tatagcttcc gcttatttag atgatcaaaa aaaaatagtt
     9541 gtggttacat caactcaaaa tgaggttgaa aaattagcca gcgatttatc tagtttactt
     9601 gatgaagaac ttgttttcca attttttgca gacgatgtgg ctgcagcgga atttatcttt
     9661 gcgtcaatgg ataaagctct atcaagaata gaaaccctgc aatttttaag gaatcctaaa
     9721 tctcagggcg ttttaattgt tagtttatca ggcttaagaa ctttattgcc aaacccagat
     9781 gtttttacaa agagtcagat tcaactaaca gttggagaag attatgatag tgatactctt
     9841 actaaacaac tgatgacaat tggatatcag aaggtctcac aggttattag tccgggagaa
     9901 tttagccgtc gaggggatat tttagatatc tatgagatta cacaagaatt gccttatcga
     9961 ttggaatttt ttggtgatga tattgatagt attaggcaat ttcatccaga aactcaaaaa
    10021 tcttttgaac aactagaagg tatttctatt aatccagcaa gtgatcttat ttttgaggct
    10081 agtgattttc aacgtggcat tgagcaatta gaaaaggctc tacaaacagc acaagatgat
    10141 aaaaaatctt atttagaaga tgtattagtt gtttcaaaaa acggttttaa acataaggat
    10201 atccgtaaat ttcaatcatt attttatgaa aaagagtggt cattattaga ttatattcct
    10261 aagggaacgc caatcttttt tgatgatttt caaaaactag ttgataaaaa tgcaagattt
    10321 gatttagaga ttgctaatct cttgacagaa gatttacagc aaggaaaggc tctttccaat
    10381 cttaactact ttacagataa ttatcgagag cttaggcact ataagccagc gaccttcttt
    10441 tcaaattttc ataagggact tggaaatatc aaatttgatc agatgcatca gctaactcag
    10501 tatgccatgc aggaattttt taatcaattt cctttgttga ttgatgagat taaacggtat
    10561 caaaaaaatc aaacaacggt tattgtacag gtagagtctc agtatgctta cgaacgactt
    10621 gaaaaatctt ttcaagatta ccaatttcgt cttcctttag tgagtgctaa tcaaattgtt
    10681 tcacgtgaat cacaaattgt aattggagct atctccagtg gtttttattt tgctgatgaa
    10741 aagttagcgt taatcacaga gcatgaaatt tatcataaaa agatcaaacg acgcgctaga
    10801 cgatctaata ttagcaatgc tgagcgtttg aaagattaca atgagttagc agtaggtgat
    10861 tacgtggttc ataatgtaca tggtatcggt cgctttcttg gaattgaaac gattcagatt
    10921 cagggaatcc atcgagatta tgttactatt caatatcaaa attcagaccg tatttctctt
    10981 ccaattgacc aaattagtag cttatcaaag tacgtttctg ctgatggaaa agaacctaaa
    11041 attaataaac tcaatgatgg tcgtttccaa aagacaaagc aaaaggtcac tagacaagta
    11101 gaggatattg ctgatgacct tctaaaatta tatgctgaaa gaagtcagca aaaaggattt
    11161 tcattttcac cagatgatga cttgcagcgc gcttttgatg atgattttgc ttttgtagaa
    11221 acagaagatc aacttaggtc tataaaggaa attaaagctg atatggagag catgcagcct
    11281 atggatcgtc ttttagtagg cgatgtagga tttggtaaga cagaagtagc tatgagggca
    11341 gcctttaaag cggtgaatga tcacaaacaa gtagctgtct tagttccaac cacagtcttg
    11401 gcccagcagc attatgaaaa cttcaaagca cgctttgaaa attaccctgt tgaggttgac
    11461 gtcttaagtc gtttccgtag taaaaaagag caagctgaaa cactagaacg tgtacgaaaa
    11521 ggtcaaattg acattattat cggaacccat cgactcctat caaaagatgt ggtcttttct
    11581 gatttaggat tgattgtgat tgatgaggaa caacggtttg gtgttaagca taaagaaact
    11641 ttaaaggaat taaaaactaa ggttgacgtc ttaaccttaa cagctactcc gattcctaga
    11701 accttacaca tgtctatgtt aggtatccga gatttatcgg ttattgagac cccaccaacc
    11761 aatcgttatc ctgttcaaac ctatgttttg gaaaataatc caggtctcgt tagagaagct
    11821 atcattcgtg aaatggatcg tggaggacaa attttttacg tttacaataa agttgacact
    11881 attgaaaaga aagttgcaga gctacaagaa ttagtcccag aagcttctat aggttttgtt
    11941 catgggcaaa tgagtgaaat tcaacttgaa aataccttga ttgactttat aaatggtgat
    12001 tatgatgtcc ttgtggcaac aacaatcatc gaaacaggag ttgacatttc taatgtaaac
    12061 actttgttta ttgagaatgc tgatcatatg ggattgtcaa ctttatatca actacgaggg
    12121 cgcgtcggaa gaagtaatcg tattgcttat gcttacctga tgtatcgtcc tgataaggtc
    12181 ctaacagaag tctctgaaaa gcgtttagag gctattaaag gctttactga attaggttca
    12241 ggcttcaaga ttgctatgcg agatttgtct atacgaggag caggtaatat tttaggggct
    12301 tctcagagtg gctttattga ttcggtcggt tttgaaatgt attctcagtt attggaacag
    12361 gctattgcta gcaagcaagg aaaaacgact gttcgccaaa aaggtaatac tgaaatcaat
    12421 cttcagattg acgcctattt gccagatgat tacatatcag atgagcgtca aaaaattgac
    12481 atttacaagc gtattcgaga aattcaatca agagaagatt atctcaattt gcaggatgag
    12541 ctgatagatc gttttggaga gtatcctgat caagttgcct atttgttaga gatagctctg
    12601 ctaaaacatt atatggacaa tgcctttgcg gaattagttg aacgcaaaaa taatcaggtc
    12661 attgttcgat ttgaagtaac ttctttaact tatttcttga ctcaggatta tttcgaagcc
    12721 ttatcgaaaa cccatcttaa agctaaaatt agtgaacatc aggggaaaat cgatatcgtc
    12781 tttgacgttc gccatcaaaa agattataga attttagaag aattgatgtt atttggagaa
    12841 aggcttagtg agataaaaat cagaaaaaac aattcagttt ttaaataata atttgaaaca
    12901 acttttagac tgaatagtat taatgacaat ggaacgaact agctctttat acttttgtca
    12961 aaaatctaag atctttgctg cgaaattagg atcttttcta ccatttaaaa aataaaaatg
    13021 ataaaatgaa gaggattgta ggagaaatta tgagactaga taaatatcta aaggtatcgc
    13081 gccttattaa acgtcgttca gtagcaaaag aagttgcgga taagggacga attaaagtta
    13141 atgggatact tgctaaaagt tcaacgaata taaaactaaa tgatcacatt gaaattagtt
    13201 ttggaaataa attactgaca gtaagagtca ttgaaataaa agatagtaca aaaaaagaag
    13261 atgctcttaa gatgtatgag ataatcagtg aaacaaggat aacattaaat gaagaagcct
    13321 agtattgttc aattaaataa ccattatatt aagaaagaga atctcaaaaa aaaatttgaa
    13381 gaagaagaat ctcaaaaaag aaatcgtttt atgggatgga tccttgtaag tatgatgttt
    13441 ttatttattt tgccaactta taatcttgtc aaaagttatg ttgattttga aaagcaaaat
    13501 caacaggtgg ttaaattaaa aaaagagtat aatgaattgt caaagaggac aaaaaaagaa
    13561 aaacaattag cagaacgact aaaagatgat aattttgtca aaaagtatgc tagggcaaaa
    13621 tactatttat cgcgtgaagg agaaatgatt tatcctattc caggactatt accaaaatga
    13681 tgatggacaa tattgtaaaa aaaatagaag catttcttgc tttttctgat aaaaaattag
    13741 cagagctgca acaggaaaat caaaaagtta aagaagaaag tcagtatatt caaaaaaact
    13801 agaaaggagt caatatgaga aaattattag cggctatgtt aatgactttt tttctgactc
    13861 ctttaccagt gattagtaca gaaaaaaaac ttatattttc aaaaaatgct gtttatcaat
    13921 tgaaacaaga tgtcgttcaa tcaacacaat tctataatca actaccctct aatccaaatc
    13981 tttatcaaga aacgtgtgct tataaagaca gtgatttaac tctaccagta ggaagattag
    14041 gtgtaaatca accattactt attaaatcgc ttgtgcttaa caaagaatct ttaccggttt
    14101 ttgagttagc tgatggtacc tatgttgagg ctaatcgaca attgatttat gacgatattg
    14161 tacttaatca agtagatata gatagctatt tttggacaca aaagaaactt aggctttatt
    14221 cagcccctta tgttttaggt acgcaaacaa ttccttcttc tttttcattt gctcaaaaag
    14281 ttcatgccac tcaaatggca caaacaaacc atggaactta ttatcttatt gatgataagg
    14341 gctgggcatc acaagaagat ctagttcaat ttgataaccg catgttaaaa gtccaggaaa
    14401 tgctcttaca aaaatataat aacccaaatt attcaatttt tgtaaagcaa ctcaacacac
    14461 aaacaagtgc tggtattaat gctgataaaa aaatgtatgc tgcaagtatc tcgaagttag
    14521 caccacttta tattgttcaa aaacaattac aaaaaaagaa attagcagag aataaaactt
    14581 tgacttatac taaagatgtt aatcattttt atggagacta tgatccattg ggaagtggta
    14641 aaattagtaa aatagctgat aataaagatt atcgtgttga agacctactg aaagctgtag
    14701 cacaacaatc ggataatgta gcaactaata ttttaggtta ttatctatgt catcagtatg
    14761 ataaagcttt ctgctcagag ataaaagctt tatcaggtat cgattgggat atggagcagc
    14821 gcttattaac ttctcgttca gctgcaaata tgatggaagc tatttatcat caaaaaggcc
    14881 aaattatttc ttacctttca aataccgaat ttgatcaaca acgtatcaca aaaaatatta
    14941 ctgttccagt tgcacataaa attggtgatg cttatgatta taaacatgac gttgctattg
    15001 tttacggtaa tactccattt attttgtcta tttttacaaa taaatcaacc tatgaagata
    15061 ttacggctat tgcagatgac gtttatggta ttttaaaatg atgacctatc aagaaatttt
    15121 taatgaaata aaaaataaag cctactttaa aaatcataga catgtgttaa tagccgtatc
    15181 tggtggagta gattcaatga atttattgca ctttttgtac ctgtttcaag acaaattgac
    15241 aattcgtatt ggtattgctc atgttaatca caaacaaaga tcagaatcag attcagaaga
    15301 agcttattta aagtgttggg ctaaaaaaca tgacatacct atttatgttt ctaattttga
    15361 aggaatattt tcagaaaaag cagcacgtga ttggcgctat gcttttttta agagtattat
    15421 gttaaaaaat aactattcag ctttagtaac agctcaccat tcagatgatc aagcagaaac
    15481 tattttgatg aggctaatta gaggaagccg attgaggcac ttgtcgggta taaaaagcgt
    15541 gcaaccattt gccaatggtc aacttataag acctttttta actttctcaa aaaaggactt
    15601 gccagaaatt tttcattttg aagattcttc aaatagggaa ttatcatttt taagaaatag
    15661 agttagaaat aattatttac cattgttaaa gcaggaaaat cctaggttca ttcagggatt
    15721 aaatcaatta gcacttgaaa atagcttact ttttcaagct tttaaggagc taacaaatca
    15781 tattactacc actgatttaa cagaatttaa tgagcaatct aagtctattc aatacttttt
    15841 gttacaagat tatttagaag gttttccaga tttaga
//
LOCUS       DAUGOH010000035        15691 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUGOH010000035 DAUGOH010000000
VERSION     DAUGOH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15691
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.035"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            70..807
                     /locus_tag="VH957_001311"
     CDS             70..807
                     /locus_tag="VH957_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8559217.1"
                     /translation="MGKEIKVKYFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALADQA
                     DALQSEEAAVVQSDTAASDALEALADQTDALQSEEAAVVKADTAASDALEALADQTDA
                     VQSEEASVVKADTAASDAWEKAATPTALDVKKTKDTTPVVKKEERQNVNTLPTTGEES
                     NPFFTAAALAIMVSTGALVVSSKCKEN"
     gene            1045..1587
                     /locus_tag="VH957_001312"
     CDS             1045..1587
                     /locus_tag="VH957_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8559218.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1596..2879
                     /locus_tag="VH957_001313"
     CDS             1596..2879
                     /locus_tag="VH957_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8559219.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCENSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2895..3755
                     /locus_tag="VH957_001314"
     CDS             2895..3755
                     /locus_tag="VH957_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEQ8559220.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3757..4722
                     /locus_tag="VH957_001315"
     CDS             3757..4722
                     /locus_tag="VH957_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEQ8559221.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4833..6116
                     /gene="aroA"
                     /locus_tag="VH957_001316"
     CDS             4833..6116
                     /gene="aroA"
                     /locus_tag="VH957_001316"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEQ8559222.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6109..6600
                     /locus_tag="VH957_001317"
     CDS             6109..6600
                     /locus_tag="VH957_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ8559223.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6808..8259
                     /locus_tag="VH957_001318"
     CDS             6808..8259
                     /locus_tag="VH957_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8559224.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDTPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8308..9699
                     /gene="rlmD"
                     /locus_tag="VH957_001319"
     CDS             8308..9699
                     /gene="rlmD"
                     /locus_tag="VH957_001319"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8559225.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVHRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQT
                     HHVECVSLLEKRS"
     gene            9851..10632
                     /locus_tag="VH957_001320"
                     /pseudo
     CDS             9851..10632
                     /locus_tag="VH957_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            10717..11118
                     /locus_tag="VH957_001321"
     CDS             10717..11118
                     /locus_tag="VH957_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEQ8559226.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(11223..12707)
                     /locus_tag="VH957_001322"
     CDS             complement(11223..12707)
                     /locus_tag="VH957_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEQ8559227.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIKASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            13081..14301
                     /locus_tag="VH957_001323"
     CDS             13081..14301
                     /locus_tag="VH957_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8559228.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            complement(14421..14786)
                     /locus_tag="VH957_001324"
     CDS             complement(14421..14786)
                     /locus_tag="VH957_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEQ8559229.1"
                     /translation="MTIYSHTYETRPNHSAKAMSSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            14901..15632
                     /locus_tag="VH957_001325"
     CDS             14901..15632
                     /locus_tag="VH957_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8559230.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKTVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVVGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
BASE COUNT         4875 a         2752 c         3330 g         4734 t
ORIGIN      
        1 ttaattataa tttccaaatt atcggtaatt taatatgcta atgcatataa aaataaaaaa
       61 ggagaaacaa tgggaaaaga aataaaagtg aaatactttt tgcgtagatc agcttttgga
      121 ttagttgcgg tgtcagcatc agtattagtc ggttcaacag tatctgctgt tgactcacct
      181 atcgaacagc ctcgaattat tccaaatggc ggaaccttaa ctaatcttct tggcaatgct
      241 ccagaaaaac tggcattacg taatgaagaa agagccattg atgaattaaa aaaacaagct
      301 attgaggata aagaagctac gacagctata gaagcagcaa gttcagatgc cttagaagca
      361 ttagcggatc aagcagacgc tttacaatca gaagaagctg cagtagttca atcagatacc
      421 gctgctagtg atgccttaga agcattggcg gatcaaacag acgctttaca atcagaagaa
      481 gctgcggttg ttaaagcgga taccgctgct agtgacgcct tagaagcatt ggcggatcaa
      541 acagacgctg tacaatcaga agaagcttca gttgttaaag cagataccgc tgctagtgac
      601 gcctgggaaa aagcagcaac tccaaccgct ttagatgtta agaaaactaa agatacaaca
      661 cctgtagtta aaaaagaaga aagacaaaac gttaataccc ttcctacaac tggtgaagag
      721 tctaacccat tctttacagc tgctgcgctt gcaataatgg taagtacagg tgcgttagtt
      781 gtaagttcaa agtgcaaaga aaattagttg ctatttgttc tagcaaatga aacaagagaa
      841 tcgaaagatt ctctttttct gatatttaaa aatgctacag tttataatac cttgaaagac
      901 taaatgttct caaactcatt agaacaagct ttaataaaac taacccagtt gtatcaaagg
      961 atagataaag actaagactg ttatagaata tttgcaaaag atttgttata atggacccaa
     1021 tacaggtatt gtgaaaggta taatatggat atttggacaa agcttgcagt gtttgctttt
     1081 tttgagactc cgaaagtaat attacggcct tttcgctatg aagatcattg ggatttttac
     1141 agcatggtta acgacactaa aaacctttat tatgtttttc cagaacaaaa aactaaggca
     1201 gcaagtgact atcttttagt acatagtttt ataaagtttc ctttaggtca gtgggcaata
     1261 gaagataaag caacccacca agtaataggt tctattagaa ttgagcatta tgatgctaaa
     1321 acgcgttgtg ctgatattgg ctatttttta aactatgcct tttggggaca aggaattatg
     1381 acagaagtcg taataaaact tgtttattta tcttttcacg aatttggtct caaaacgttg
     1441 cgtattataa ctcatttaga aaataaggcc agccagaaag tagctaaaaa agcaggtttt
     1501 caactaaaaa cctgttttaa aggaagtgat cgtaatactc ataaaatctg catttataaa
     1561 atgtaccaac taactaatga taggtgataa tcattatgag caaacatcaa gatattttag
     1621 attatttaga aaaacttgct attggtaaaa aagtgagtgt tagaagcatt tcaaaccact
     1681 taaaagtaag cgatggaaca gcctaccgtg ctattaaaga ggcagaaaat cgaggtattg
     1741 tcgaaaccaa accaagaagt ggaactgttc gtattgaaaa aaaaggacgg gttcgtattg
     1801 accgtctgac ctattccgaa attgctcgga tcagtgattc ggaagtgcta gcgggacatg
     1861 ctggtttagg acatgaattc agtaggtttt caattggtgc tatgactcaa caaaatattc
     1921 gtcgttactt ggtcaaagga gggttattaa tagttgggga tcgtgaaacg attcaactct
     1981 tagctcttga aaaccataat gccattttgg tgacgggcgg atttccagta tccaaacgtg
     2041 ttattgaaat ggcaaataac caacgaatcc cagttatggt aactcattat gataccttta
     2101 ctgtggcaac aatgattaat cacgcgctat ctaatattcg tattaaaaca gatctcaaaa
     2161 cagttgaaca ggtaatgata cctattacag attatggtta cctttgcgaa aacagctctg
     2221 ttgaagaatt caatacatta ataaaaaaaa cacgacaagt caggtttcct gtattagatt
     2281 ataaaagaaa agtgattggt gtagttagta tgcgtgatgt ggtggatcag ttgccaacaa
     2341 ctaagcttac caaggtcatg tctaaaaatc caataacggc tagaccaaat actagtcttg
     2401 ctaatattag ccagaaaatg atctttgaag atttaaacat gttacctgtc actgacgaag
     2461 aaaacaattt acttggtatg attactcgta gacaagcaat ggaaaatttg ccaaatcacc
     2521 aacccaataa cccctatact tatagtgagc aaatactttc taaccttgaa gaaacggttg
     2581 attattacca agtagtagtt gagccaacaa tgattgatag tgctggtaac atgtcaaacg
     2641 gtgttatttc agagttctta aaggaaatta gtatcagagc cctcacgaaa aagcaccaaa
     2701 aaaatatcat tatcgaacaa atgatggtat actttttaca tgctattcaa attgaggatg
     2761 aattaaaaat atatcctaaa atcattactg aaaatagacg aagcagcacc attgatattg
     2821 aaatttttgt ggatgatcaa gtgattgcta aagctattat tacaacgaaa ataaattaga
     2881 ggagtaacaa aacaatgata acattaaaat cagcccgtga aatagaagcg atggatagag
     2941 caggagactt cttagcaggt atccatattg gcttaaggga tattattaag cctggtgtgg
     3001 atatgtggga agtggaagca tatgttcgtc gccgttgtaa agaagacaac gttcttcctt
     3061 tgcaaatagg ggttgatggt cacatgatgg actatcctta tgcgacctgt tgtggtctaa
     3121 atgacgaagt agcacatgcc tttccccgtc attacattct gaaagaaggg gatttgctta
     3181 aagttgacat ggtactcagt gagcctttgg ataaatcaat tgttgatgta gcagctttag
     3241 attttgataa tgtgcctgag atgaagaaat ggacaggatc ttatactggt ggtttagctg
     3301 actcttgttg ggcttatgct gttggaacac cgtctgacga aataaagcaa ttaatggatg
     3361 tcaccaaaga agccatgtac cgtggtattg aaaaagcagt aattggcaat cgtattggtg
     3421 atattggcgc agctgttcaa gaatacgctg aaagcttcgg ttatggtgtc gtgcgtgatc
     3481 ttgttggtca cggtgttggt cctacaatgc atgaagagcc aatggtacca aactatggaa
     3541 cagcaggtcg tggacttcgt ctaaaagaag gcatggtctt gactgttgag ccaatgatta
     3601 atacaggaac ttgggaaatt gataccgaca tcaagacagg ttgggctcat aaaaccctag
     3661 atggtggttt atcttgccaa tacgaacacc aatttgtgat tactaaagat ggtcccgtta
     3721 ttttaacaag tcaaggagaa gaaagaactt actaaaatgg cagaaaaaaa atggtttgat
     3781 aaggtactgt ccaagtggca gtatgaaccc attcaagtct ttatgaggca tttacaaagt
     3841 gcagaaatgg atttatctgc cattgcggtt gcgtattacc ttatcttaac ggcctttcca
     3901 ttaattgtta ttgcagccaa tatttttcct tacctcaata ttgatattgc tgatttgtta
     3961 cgtttaatga agcaaaattt gcctaaagat atttttagac cggcttctgc aattgtagaa
     4021 aatattttct ctaaaccgtc tggaagtgtt ttgggagtag cgactttgac aggattatgg
     4081 acaatgtctc gaagtttgac atcgctgcaa aaagctatta ataaagccta tggcgcttct
     4141 cagcatcgag atttctttat cggacacttg gttggtttgt tgaccagttt aattatttta
     4201 tttttattag cctttgcctt aatcttttca acattttcta aagctgctat tcaagtgctg
     4261 gataagcatt accatttgag tgataatatc acaacgattt tcttactcct cattcaacct
     4321 attacagttt tgattatttt tgttggcttg atgctactat attttttatt acccaatgtt
     4381 aagattaaaa aaattcgcta cattttacca ggaaccctat ttacatcttt tgtgatgaca
     4441 tttttgagta atctggttgg caattacgtt gtgtataatg ttgagcggat ggtagatatt
     4501 aaaatgtttg gttcagttat gatttttatc atcatgctat ggtttatttt cttagcaaga
     4561 atcctgattt taggagctat atttaatgcg acctatcaag aaatgtcctt ggggaaatta
     4621 gaaggtcgta gtggtgatat gatcgctatc cttaaaaaaa cacttgggaa tgattcagat
     4681 ctatctcctt cacagtctat cgaagatagt cacactgatt gatacaaaaa agataataag
     4741 tcgtggagtg agaaactatt ttcttgcttc attttttatg aggataaata gaaaatcatt
     4801 gatcttagca aatagaaagg cagataaaac ggatgaaatt gcgaacaaat gcaggaccat
     4861 tacagggaac gattcaagtt ccaggagaca agtccattag tcaccgggca gtcatattag
     4921 gagctgttgc taaaggggaa acacgagtaa aaggactctt aaaaggagaa gacgtgcttt
     4981 ccacgattca agcctttagg aatttggggg tccgtatcga agaaaaagat gaccagcttg
     5041 tgatagaagg tcaaggtttt caaggattga ccgctccttg tcagacactt aatatgggaa
     5101 attctggaac ctctatgcgc ctcattgctg gcttattggc aggtcaacct tttagtgtca
     5161 aaatgattgg cgatgaaagc ttatccaaac gtcctatgga tcggattgtt tatccgttaa
     5221 agcaaatggg ggttgagata tctggagaaa cagataggca atttcctcca ctacaattgc
     5281 aaggtaatcg taatttacaa ccaatcacat atactttgcc tatctcttct gctcaggtta
     5341 agtcagctat tttgttagca gctttgcaag caaaaggaac aacacaggtt gttgaaaaag
     5401 agattactcg aaaccataca gaagaaatga ttcaacaatt tggtggacga ttgatagttg
     5461 atggtaaacg cattactttg gtgggacccc agcagctcac tgctcaagag ataactgtcc
     5521 ccggagatat ttctagtgca gctttttggc ttgtcgccgg cttaattatt cctggttcgg
     5581 agctcctttt aaagaatgtt ggagtcaatc cgacacgaac agggattctt gaagtggttg
     5641 aaaaaatggg agcacagatt gtctatgaag atatgaataa gaaagagcaa gtaactagta
     5701 ttcgagtggt atattctcac ttgaaaggaa ctatcatatc aggaggtctt atccctcgat
     5761 tgattgatga acttcccatc attgcacttc ttgcaaccca agcacaagga acaacctgta
     5821 ttaaagatgc tcaagaatta cgagtcaaag aaacagatcg tattcaagta gtaactgata
     5881 ttcttaacag tatgggagct aatatcaaag cgacagcaga tggcatgatt atcaaaggcc
     5941 ctacggtact atatggggct aacacaagta cctatggaga tcatcgtatt ggtatgatga
     6001 cagcaattgc agccttgctt gttaaacaag gacaggtcca tttggataaa gaagaagcca
     6061 tcatgacgtc ttatccaacg tttttcaaag atttagaaag gctgtgtcat gactaaagtg
     6121 ttattgggat ttatgggagt ggggaaaaca acggtttcga aacacctaag tatgcactgt
     6181 aaagatatgg atgctattat tgaagctaaa atcggtatgt ctattgcagc tttttttgaa
     6241 cagcatggag aaatagcatt tcgaacaatt gaaagtcaag tgttaaaaga tctattgttt
     6301 gcaaatgata atagtgtcat cgtaacaggt ggcggtgtag tggttttaca agaaaatcga
     6361 caattactga gaaaaaatca ccagcataat attttattgg tagcttcttt tgaaactttg
     6421 taccagcgtt taaaacatga taaaaagtct caaagacctc tatttcttaa gtactctaag
     6481 gaagcatttt atgaatttta tcaacaacgt atggtatttt atgagggact ttcagattta
     6541 gtaatcagag ttgaccatcg tacgcctgaa gaagttgcca acatcattga gggttattag
     6601 taggtcattg tcgtaatctg atatttatgg ttttaaacag gtatctgtct aaagcacttc
     6661 ttatggcaag ttggctttat taaatattag gaaataatct tgattattct ataatgatta
     6721 aaattttgag aggacaatct ggctaatata ggttataatg gtagtattcg ttaaaagtgc
     6781 aattgtaata ctaagagatg ataagatatg acaaaatacc ccatgggtgg ccttagtcac
     6841 catgaagaat tacgttattt ttatctccta aggaatttga gttaccttag tgagaatgaa
     6901 aaaaaagagt ttgctttttt aaaatctaaa ttggaaattg gtcgagctta tgctccttct
     6961 aaacagcatt ataggaagtc aaaacggcaa gaaccttact ttgaagatga ctactataac
     7021 gactactcac caaatgattt actagaagat gatgacgtca atcatgactc ttcttttgtt
     7081 ccatatggtt taccgatata tcctaaagaa gacagatatt taaacaaaaa aacaaaactt
     7141 acagctcgta gacctataga tactccgcag cctattgatg aagacgatgc ttttttaaca
     7201 gagtctgttg ctcgttgtgc tcttcctaga tctcaaaaaa gaaagcataa gaaaaaagga
     7261 tgtatgaaat ggttttttaa cattcttggc ttattgctaa tgactgtgct tatggggtta
     7321 gggttgatgt ttgcaaaagg ggtttttgat atttctacta ataaagctaa ttacaaacca
     7381 gctgtttccc aagcttttga tggtcaagaa actcaagatg gtacgaacat tctggttttg
     7441 ggttctgacc aacgagttac tcaaggttct acagatgctc gcacagatac cattatggtt
     7501 gtcaatgtcg gcaaccatgc taaaaaaata aaaatggtct cttttatgcg tgacactttg
     7561 attaacattc caggatacag ttataatgat aattcgtatg atcttaaatt aaatagtgca
     7621 tttaatcttg gagagcaaga agatcaccac ggagcagagt acgttcgacg ggccttaaaa
     7681 cataattttg atatcgacat taagtattat gtgatggtag attttgaaac atttgcagaa
     7741 gctattgaca ccttgtttcc aaatggtgtt aagattgatg ccaaatttgc gacagtaggt
     7801 ggtgtagctg ttgactccgt agaagttcca gatgacctgc gaatgaaaaa tggggttgtt
     7861 cccaaccaaa ccatcgaagt tggagaacaa cgcatggatg gtagaacctt gctcaactat
     7921 gctcgtttcc gtaaagatga cgaaggagat ttcggacgaa ccgtccgtca gcaacaggtt
     7981 atgtcagctg ttatgtccca aatcaaagac ccaactaaac tctttacagg gtctgcggct
     8041 attggtaaaa tctatgcgct gacttcgacc aatgtttctt ttccatttgt tgttaaaaat
     8101 ggtgtttctg ttttaggaag tgggaaaaat ggagttgagc acgtgaccat cccagaaaac
     8161 ggggattggg ttgacgaata cgatatgtat ggaggacaag ccctttacat agattttgat
     8221 aagtatcaga aaacgttagc caaattaggt ctgcgctaag atatggtata atggagagta
     8281 actaaagttg ctcttctttt ttgagcaatg gttagcccta gaaaaggaaa aagaataaga
     8341 atgttgaaaa aaaatgatat tatccaagtt gctatttcag atttaagcca tgagggagca
     8401 ggtgtcgcta aacacgatgg ttttgttttc tttgttgata atgccttgcc agaagaagtg
     8461 attgacatgc gtgtcttaaa ggtcaataaa aacagcggtt ttggcaaagt agaagcctat
     8521 cattacctgt cgccagctag aaatgcagat gtcaatttaa cttatttgcg aacaggcatt
     8581 gcagaccttg gacatctaac ttatgaagac caactgactt tcaaaaagaa acaagttcag
     8641 gacagcctct ataaaattgc tggaatcagt gacgtgacag tcgaaagcac gattgggatg
     8701 acagaacctt tagcttaccg aaataaggct caagttcctg ttagacgtgt taatggtcag
     8761 ctagaaacag gctttttccg caagcattct catgacttga ttcctatttc ggattattat
     8821 attcaggaca aagagattga tcgtctcatt aattttaccc gtgatttatt acgccgcttt
     8881 gatattaaac cgtatgacga aacagaacaa acaggtctct tgagaaatat tgttgttcac
     8941 cgaggccatt actctggaga aatgatgctg gtcttagtga ctacacgccc aaaagttttc
     9001 cgtgttgacc aagtcattga aaaaatcgtt gaagcttttc cagcagtggt gtctattatt
     9061 caaaatatta atgataagaa caccaatgca atctttggta aagatttcaa aacgctttac
     9121 ggcaaggata ccattactga tagcatgctt ggaaacaact atgccatttc tgcccagtct
     9181 ttctaccaag tgaatacggt tatggcagaa aaactctatc aaacagctat agccttttca
     9241 gacctttcta aagatgacat tgtgattgac gcctactcag gtatcggaac cattggccta
     9301 tcatttgcta aaacagttaa agctgtttat ggtgttgaag tgattgaagc agctgttaga
     9361 gatgctcaac acaatgccgc tcttaatggc atcaccaatg cctactttgt cgcagatacc
     9421 gcagaacatg ccatggcaac atgggcgaaa gatggcatta aaccaagtgt tattctggta
     9481 gacccgccac gaaaaggctt aacagaaagt ttcatccaag ccagcgtggc aatgggacca
     9541 caaaaaatta cctacgtttc ctgcaaccca gccaccatgg cgcgtgacat caagcgttat
     9601 caagagttgg gttacaaact ggccaaagta cagcccgtag atttgtttcc ccagacgcat
     9661 cacgtggagt gtgtaagttt acttgagaaa cggagttaaa gagtccgcct cactctgtta
     9721 tttcaaggtg agacgctcaa aaggtccact ggaccttttg actcccgcag acccatcacg
     9781 tcgagtgcgt agtgttgcta atcaaggagt aaggcagctg cctccacatg acaaaaataa
     9841 ggagaaacga atgcctatta ccaaacacga gattcccctt ttagaatgtg atagtaatcc
     9901 atcagccgtc attataccta cacatgaagg tctacagcta agtgtgtcta tgctttctta
     9961 gaagacgaga ttgaagcttt tgctttagac catcaaggta aaaaagtagc agaattcatt
    10021 tcagccacaa aggtttaccc tgtttatcag ataccttata aaggccaaga catttgccta
    10081 gctcaagctc ccgttggctc agctcctgcg gcgcaattca tggactggct gattggttat
    10141 ggggttaaag aaatgatcag tacaggaacc tgtggcgttt tggttcctat cgcagaaaac
    10201 cgttttttag tgccagttaa ggctttgcga gatgaaggaa caagttatca ttacgtggca
    10261 ccatcttgtt atattgatat tgatcctaag atgcttagac cgatagagaa aacgctttca
    10321 gcacaggggt tagcttatca agaggtcatc acctggtcaa cagatggttt ttaccgagaa
    10381 accaaagaaa aagtggctta tcgccaggaa gaagggtgtt cggttgttga gatggaatgt
    10441 tctgccttag cagcagtagc tcaattaaga ggcatccttt ggggacaact cttatttaca
    10501 gcagatactc tagcagatgt agaggtttac gatcaacgca accggggcgc tgattccttt
    10561 agttttgcgc ttcatttatg cttggaagtg ttcaatacgc tagaaaagga tggaaaggct
    10621 actgattttt gaaacatgag ctctgccttc tgttcctatt tgtagtataa tgaggcttgt
    10681 attgctttta gactaagctt agaaaagaga aaaacaatgt cagatttaac acaagagatg
    10741 accttaaatg ttattagtat ttttgataat taccaaattg aacttgctga aaaaggacac
    10801 cttattttaa gtactgaagt gactgagacg gctttgaatt actatgggaa tgctcatggt
    10861 ggttatcttt tcactctatg tgatcaagta ggtggtttgg ttgctagaac tactggcgta
    10921 gaatctgtca ccttacaggc caatgctaac tatttaaaag cagggcacaa gggagacaag
    10981 ctgatggttg aaggtcgatt ggttcatgga ggtcgaacca cgcaggtggt tgatgtgacg
    11041 attcataacc aaacaggagc tcttctaaca aaaacaagct tgaccatgtt tgtgactggc
    11101 cgacgtcata acgggtgatt aatgaatcaa taaaggaaaa aagtcccaac tctctgagaa
    11161 ttgggacttt tttcctttat tgagagatac cataaatcac ccgttagacg ggtggttata
    11221 gtttatttac ggtaaagttt gtgatgttgg taaacagggt caaaagtaat atttacccca
    11281 agttttcgga gtacattttt atcttcttcg gttaagataa cggtagaatg ggcttcgcta
    11341 cctttcaaat tgccgagttc tttcatggct agattagctt cttcactagt catagcagta
    11401 atggctaacg caatcagaat ttcattggaa tgaagccgcg gattgtgact gcctaagtgg
    11461 ttcactttga gcccttgaat aggtttcacg tattcgggtt caatcaaatg agtggtttta
    11521 tcaatctttg ccaaggtttt aatcgcattg atgataacag ctgcagttgg tccaaagagt
    11581 tcagatgttt tacctgtcac aatttgccca tttggtagtt ggagagcaag ggcaggttgg
    11641 cctgtttgct ctgctttttg atgagcagct acagtaacgt gacgatcgtc aggggtgaca
    11701 ccgatatcat tcatcaagag ctcaattttt ttgacagcag attctgtgac ccgctctgcc
    11761 ttaaaatcca cgagggtttg gtaataacga cggatgattt cttgtttaga agctttgata
    11821 gcagcttctt cattgacgat agaaaaacca accatgttaa cacccatatc ggttggtgag
    11881 gcataaggag acttgctcaa aatacgctcg aaggtccgat ttaagacagg aaagacctcg
    11941 atatcacggt tgtaattaac ggccgttttg ccataagttt ccaaatggaa ggggtcaatc
    12001 atattcacat catctaggtc tgccgtggct gcctcataag ccagattgac agggtgatga
    12061 agaggaagat tccaaactgg gaaggtttca aatttagcat agccagactt aaccccattg
    12121 atttggtcgt gatacatttg ggacatgcaa gtggctaatt ttccagaccc agggcctggt
    12181 gctgtaacaa cgataaggtt acgactcgtt ttgatgtaat catttttccc catcccctca
    12241 gatgagataa tatgattaat atctgtcggg tagcccttga taggataatg caggtaagaa
    12301 gcaatgccat ttttttcgag ttgcttgcga aaggcatctg cagcgggttg gttattgtat
    12361 tgagtaataa cgacagaacc tacgtaaata tctaacgtgt taaatttgtc aattaagcga
    12421 aagacttctt ggtcataaga aatgcctaaa tcaccacgcg ctttagaatg ttcaatatta
    12481 ttagcgttaa tggcaattac aatttcgact tgttctttga gctctttgag taatttaatc
    12541 ttattgtcag gttcatagcc aggaagtaca cgggcagcat ggtaatcttc taacatttta
    12601 ccaccaaatt ccatgtaaag tttgccatca aattggctga tacgttctaa aatatgatct
    12661 ctttgcaagt ttaaatactt gttagaatca aaagcaatag tcttcatttt ttcacctctg
    12721 taaagcatta taacaaagaa ataccaagaa agaaaaggtt ttttgcaggg atacctcatt
    12781 tagtgacttt ttaaaaaaac ttaggcttgg ttcttagaag aaaaatgtat ccgctatgtt
    12841 caaaagaact tgacaattaa aatgagcttt actatactag taacaattaa atactacttt
    12901 aaacatgttc cgtgaagcat gaaagtctta acagtaaaga gagttttttt gtcatctctt
    12961 attatttagt gaactttgat ggacttgcgg acttgtttcc aagtcttttt ttgacctttg
    13021 ggcaaagggt attcaattaa ttaaggtagt cagtgagcta ctattaagaa ggagacaatt
    13081 atgtcaacat tatcattgga caccacaaat aagcgagctt tagtggcagc tattgcagct
    13141 tcaggaacgg atgacttgaa tgtcatgttt cttgcctttt ccatgtcttc cattatgaca
    13201 gacttgggtc ttagtggcac tcagggtggc tggattgcga ccattaccaa tttaggaatg
    13261 ttggtgggag gcctcttatt cgggttgctg gctgataggc accacaagtt taaggtcttt
    13321 aaatggacga ttttactgtt ttcagtagca acaggattaa tttattttac ccagtctttg
    13381 ccctacctgt acctgatgcg atttattgct ggcataggag ttggaggtga gtacggtgta
    13441 gccattgcca taatggcagg gattgtacca ccagaaaaaa tgggtcggat gtcttcttta
    13501 aatggtattg ctggccagct tggctccatt agttcggctc ttttagcagg gtggctggct
    13561 ccaagtctag gctggcgtgg cctttttctc tttggattac ttccgattct cttggtgatt
    13621 tggatgactt tagccataga tgaccaaaaa atttgggatc attatgggca agaggaggaa
    13681 gaatgcagtc aaccaattaa aatcaatgaa ctattcaaaa caaaatcctt aacagctcaa
    13741 acccttgctt taatggtcat gacgactgtg cagattgcgg gctattttgg aatgatgaat
    13801 tggttgccaa ccattattca aacaagctta aacctttcag taaaaagttc gtccttgtgg
    13861 atggtggcta ctattgtcgg catgtgtttg gggatgctgt gttttggtca gcttttagat
    13921 tgctttggtc cacgtctgat ttattccctc tttttattag catcatctat ttgtgtttac
    13981 ctttttcaat ttgccaattc catggcgagt atggttattg gaggtgctat tgtcggtttt
    14041 tttgtcaatg ggatgtttgc tggctacggg gctatgatta ccagacttta tccccatcac
    14101 attcgatcca cggctaataa tgttattttg aatgttggcc gtgctctagg aggattttcg
    14161 tccgttgcta ttggtagtat tttagatgcc tcaggtattt caatggtcat gattttccta
    14221 gcttctctgt atgtgattag ttttggagcc atgtggtcta ttggtcagtt aaaagcagaa
    14281 cgctaccaac aattgcgtta gcaaagagat gggtgttagt atttgagtta ctttcactca
    14341 caaagctatt ttattgattg agataaccaa aaaggtaagc acttagggat tgcttacctt
    14401 tttggttctt ttcttttgtt ttactccgct actttggcca taaaatgttt actgttcacc
    14461 ctaactctag tatgacaggc ttttccaatg agttgttctc ccacaaaagc ttccaagcgg
    14521 aaatcgtatt ttcgaccttc ttctttaagg gctgtaatga tgattgtaac aggatctcca
    14581 atggctgaag ctgccaaatg ttggatagct atctcgctgc caaccgttgt aaagtcactg
    14641 tcgagctgtt cttgggcaaa taagtaagaa gcattttcca taaaagcaac aagagcagga
    14701 gtagctagga cattcagcgt tcctgagctc atggctttag ccgaatgatt gggacgggtt
    14761 tcataagtgt gagaataaat agtcataagt taatctcctc gtttctataa gcctattata
    14821 atatattaag cgcttacagt catgaaacca ctgttttttt atgttatact taataatgaa
    14881 ttttctttga aagggttatg atgcgtttag ataaattttt agtggcaact ggtgttggaa
    14941 ctaggagcca agtcaaactt ctcttaaaaa agaaggctat cttcgtcaat caaaaggttg
    15001 aaacctctgc caaagcacac attgatgaat acaaggattt ggtgacgtat caaggcacgc
    15061 ccttggtcta tgaatccttt gtttattacc tgttaaacaa gccgtcaggg tatgtgtcgg
    15121 caacccagga cagacagcag gctactgtta tggagttgtt agatgacacg gctaggcaaa
    15181 aaacagtttt tcctgtgggt aggttagata aggatacccg tggacttttg ctcttgacca
    15241 ataatggaca actagcccat gaccttttat cccctaaaaa acatgttacg aaagagtact
    15301 tggctaaagt agtaggcatc atgactgaag ctgataaaga ttattttgct agaggtattt
    15361 ccttaaagga tcaccagtgc ctacctgctc atttagaagt gcttgctagt gatttacagc
    15421 agcaaacaag tttggttaaa attaccatac aagaaggaaa attccatcag gtgaaacgca
    15481 tggtagcagc ctgtggaaag ggagtgcttg acttgcagcg tctcagcatg ggaccattaa
    15541 aactagaccc tagccttgca gaaggggagt ttaggcgcct gacgcctgag gaattgcaaa
    15601 gcctggcacc ttattgtcag agctcactat aaaaagaaac ctcccctgtc agtactgacc
    15661 ccaaaaagtt ggacaaataa ttattgaaag g
//
LOCUS       DAUGOH010000036        15529 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUGOH010000036 DAUGOH010000000
VERSION     DAUGOH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15529
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.036"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(22..2013)
                     /gene="uvrB"
                     /locus_tag="VH957_001326"
     CDS             complement(22..2013)
                     /gene="uvrB"
                     /locus_tag="VH957_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEQ8559231.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            2206..4380
                     /locus_tag="VH957_001327"
     CDS             2206..4380
                     /locus_tag="VH957_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8559232.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGNFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATISDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            4380..5120
                     /locus_tag="VH957_001328"
     CDS             4380..5120
                     /locus_tag="VH957_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559233.1"
                     /translation="MTELKIDVQGLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEAAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(5268..5420)
                     /locus_tag="VH957_001329"
     CDS             complement(5268..5420)
                     /locus_tag="VH957_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559234.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(5417..6796)
                     /locus_tag="VH957_001330"
     CDS             complement(5417..6796)
                     /locus_tag="VH957_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8559235.1"
                     /translation="MSHFSDKFMDISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(6974..7423)
                     /locus_tag="VH957_001331"
     CDS             complement(6974..7423)
                     /locus_tag="VH957_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEQ8559236.1"
                     /translation="MIISAEGDVSIHHCFEAMLISLQEDYRQNTLRRLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANHFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(7420..7755)
                     /locus_tag="VH957_001332"
     CDS             complement(7420..7755)
                     /locus_tag="VH957_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8559237.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRCES"
     gene            complement(7758..8069)
                     /locus_tag="VH957_001333"
     CDS             complement(7758..8069)
                     /locus_tag="VH957_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8559238.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(8092..10086)
                     /locus_tag="VH957_001334"
     CDS             complement(8092..10086)
                     /locus_tag="VH957_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8559239.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVSQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNIFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTEMFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKVHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQTLLEEPNYSKFMTVFTPLIHD"
     gene            complement(10192..11286)
                     /locus_tag="VH957_001335"
     CDS             complement(10192..11286)
                     /locus_tag="VH957_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEQ8559240.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGCIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIDPS"
     gene            complement(11295..12695)
                     /locus_tag="VH957_001336"
     CDS             complement(11295..12695)
                     /locus_tag="VH957_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8559241.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGNPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            12920..13615
                     /locus_tag="VH957_001337"
     CDS             12920..13615
                     /locus_tag="VH957_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEQ8559242.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            complement(13620..13778)
                     /locus_tag="VH957_001338"
     CDS             complement(13620..13778)
                     /locus_tag="VH957_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559243.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(13847..15160)
                     /gene="obgE"
                     /locus_tag="VH957_001339"
     CDS             complement(13847..15160)
                     /gene="obgE"
                     /locus_tag="VH957_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEQ8559244.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAEAEKEFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD"
     gene            complement(15217..15345)
                     /locus_tag="VH957_001340"
     CDS             complement(15217..15345)
                     /locus_tag="VH957_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEQ8559245.1"
                     /translation="MAFGENGPRKKTTFEKVTMVVVILMVLVTVGGLIASALSVLM"
BASE COUNT         4668 a         3334 c         2789 g         4738 t
ORIGIN      
        1 aatataagct ttattcaaaa cctagtccat taatttaagt tctaaaatca agtctcgcat
       61 ttgagctgcc aattcgaaat caagtaattc agctgcctct tgcatttgtt tttgcagagc
      121 attgatcgct tcttttcgtt ctcctcttga catactttca taatccatct cttctttcga
      181 tatatcattg tggcttgttt tacttatact aataaggcct ctgatgtctt tttttatagt
      241 ttgtggaacg atgccgtgcg ctttgttata tgctatttga atctcacgac gacgagccgt
      301 ttcgtcaata gcccgctgca tagaatctgt catcttgtcc gcatacataa tgacatgacc
      361 atctacgttt cgagctgctc taccgatggt ctgaatcaag ccgcgttcat tacggaggaa
      421 accctcttta tcagcatcca aaatggctac aagactaact tctggcacat caatcccttc
      481 acggagcaga ttgattccaa tcaagacatc aaaaacacca agtcgtaaat cacgaataat
      541 ttctgtccgc tctaaggttt taatatcact gtgcatatac ttgaccttga cacccatctc
      601 ttttagataa tcagtcaaat cttctgccat ttttttagtt aaggttgtga tgaacgtccg
      661 ttcatcgcgc gctacgcgct ggttaatttc tcccaacaaa tcatccattt gccccatact
      721 tggccttaca tcaatttcag gatcaagtag cccagtcgga cgaataattt gctcaataat
      781 tgtattagtc tgtgacattt cgtattcacc aggcgttgct gaaacataga caatttggtg
      841 cacatgactt tcaaattcct cgcgtcttaa gggacgatta tcaagagctg atggcaatcg
      901 aaaaccatag tcaactagca tttgttttct ggcttggtca ccattataca tgcctttgat
      961 ttgtcccatt gtcatgtgac tttcatcaat cataattaaa aaatcttctg ggaagaaatc
     1021 taacaaggta taaggaggtt ctcctggtga cctgccatcc atatgacggg aatagttttc
     1081 gactccgcta gtatagccca tttcacgtaa catttcaata tcatattccg ttctttggcg
     1141 taatcgctgt gcttctagta gtttaccttc agattcaaat aactgtaact gctctgctaa
     1201 ctctgcttga attttggcta ttgattgctc catatgctca tcatttgtta caaagtgagt
     1261 agctggaaat aaaaccaaat ggtcaacttc tccaatagtt ttcccagtta aactttcgat
     1321 ttcacatata cggtcaatct catccccgaa aaattccacc cgaaaagcat gttcatccct
     1381 ggatgctgga aagacctcaa caacatcgcc acgtacacga aaacagccgc gttgaaaatc
     1441 aatatcatta cgctcaaatt gaatatctac taattgattt agcaaagtgt cacgtgatat
     1501 ctcctgacct ggacgtaggc tgactgctga atctgcgtac tcttttggcg aacctagtcc
     1561 ataaatacaa gatacagaag ctaccactat gacatcgtta cgctcaagta aagaagaggt
     1621 ggctgaatgg cgaagtttat cgatttcatc attgactgaa ctatcttttt cgatataggt
     1681 gtcgcttgat gggacatatg cttcaggttg gtagtaatca taataagaaa caaaatattc
     1741 cacagcattg tctggaaaaa attctttaaa ttcaccatat aattgtcctg ctaaggtttt
     1801 attgtgagct atcactaagg taggtttatt tactttacta attacttggc tcatggtgta
     1861 tgtttttccc gttcctgtag cacctaggag aatctgagct ttttctccgc cctcgatatt
     1921 atcaactagg ctttcaatag cttgtggctg atcaccagac ggtttatact ttgattttag
     1981 tttaaatggt ttatcatcac gtttatcaat cattttatac cctctaatag tcttactctc
     2041 ttatagacta ttttaacata gataagccag aatcacctcc aataagcgta aaaaacatgt
     2101 catttacatg ttatgtttta tgacatataa ataacaaatt tcttgcttaa tgttcaatat
     2161 tttgttataa ttaaccatat tttttagttt tataaggaga ttagtatgac gcacaaaata
     2221 aaagtattgc tgcttgcgat aatgtctatt tttttgacat gcaatattgc aagtgctgaa
     2281 actattgcta ttgtttcaga tacagcttat gccccatttg aatttaaaga ctcagatcaa
     2341 atttacaaag gaattgacgt tgatattatt aatgaagtag ccaaacgtca atcttgggat
     2401 ttcagtatga gtttcccggg ttttgatgca gctgtaaatg ctgttcaatc tggtcaagcg
     2461 agtgctctaa tggccggtac aaccattacg aatgctcgta agaaagtctt tcatttctca
     2521 gagccatatt acgataccaa aattgtcatt gcgacacgta aagccaatgc catcaaaaaa
     2581 tacagtgact taaaaggaaa aacggtcggt gttaaaaatg gaacagcggc tcaagccttt
     2641 ttgaataact ataaaaaaaa gtatgattat actgttaaaa catttgacac aggtgatctt
     2701 atgtataata gtttatctgc tggttctatt gccgctgtta tggatgatga ggcggttatc
     2761 caatacgcaa tcagccaaaa ccaagatatt gctattaaca tgaaaggaga gcccattgga
     2821 aactttgggt ttgctgtcaa aaagggaagc ggatatgatt atctagttaa tgatttcaat
     2881 acagctctta aagctatgaa agctgatggt acctaccaag ctatcatgac caagtggtta
     2941 ggcacagatg ataaagctac caccagtcag gcaacgggaa atccatctgc caaagctaca
     3001 cctataaagg acagttataa aattgtctct gattcgtctt ttgcaccttt tgaatttcaa
     3061 aatggtaagg gcaaatacgt tggtattgac atagaattaa tcaaagctat tgctaaacaa
     3121 caaggtttca aaattgaaat cgctaatcca ggtttcgatg ctgccttaaa tgctgtgcaa
     3181 tctagccaag cagatggggt cattgctggt gcaactattt ctgacgctcg taaagctatc
     3241 tttgattttt ctgatcctta ttatacttct aatataattt tagctgttaa agctggaaaa
     3301 aacatcaaga actatgaaga cttagacaga aaaacagtcg gtgctaaaaa cggcacttca
     3361 tcttactctt ggttaaaaga aaacgctcct aaatatggtt ataatgtcaa ggcatttgat
     3421 gatggttcta gcatgtatga tagcttaaat tcaggttctg tagatgctat catggatgat
     3481 gaggcggttc ttaaatacgc tatctctcaa ggtcgtcgct ttgaaacacc tcttgagggc
     3541 atttctactg gtgaagttgg ttttgctgtc aagaaaggaa ccaatccaga attaatcgaa
     3601 atgttcaaca atggcttagc tgctctcaaa aaatctggtc agtatgatga cattatagat
     3661 aaataccttg actctaagaa agctgcaact ccttctgaaa aaggtgctga tgagtctact
     3721 atttcaggcc tattatcaaa taactacaaa caactattgg caggacttgg aaccacgctc
     3781 agtttaaccc ttatttcatt tgctattgct ataattatcg ggatcatctt tgggatgatg
     3841 gccgtgtcac caactaaatc acttcgactc atttcaacgg tctttgtgga cgttgttcga
     3901 gggattcctt tgatgattgt ggctgccttc attttctggg gagtaccaaa ccttatcgag
     3961 agtatgaccg gccaccagtc accgattaat gatttcttag ctgctacaat tgcactgtca
     4021 cttaatggcg gagcctatat tgctgaaatt gttcgcggtg gtatcgaagc tgttccagca
     4081 gggcaaatgg aagctagtcg aagtcttggt ttgtcttacg gaaccacgat gagaaaagta
     4141 attctcccac aagctgtgaa actaatgtta cctaacttta tcaatcagtt tgttatttca
     4201 ttgaaggata caacaatcgt ctcagcaatt ggtttagtgg aactcttcca aacaggtaaa
     4261 atcattattg ctagaaatta ccagtcgttc cgcatgtatg ctattttagc aattatttac
     4321 cttatcatga ttacactctt aacaagactt gcaaaacgtt tagaaaagag gcttaactaa
     4381 tgacagaatt aaaaattgat gttcaaggtt tacacaaatc ttatggtcaa aatgaagtct
     4441 taaaaggaat tgatgccaaa ttctacgaag gtgatgtcgt ttgtatcatt ggtccttctg
     4501 gttctgggaa atcaaccttt ctacgtaccc tcaaccttct agagacgatt accagtggga
     4561 aggtcatggt ggacggtttt gaattatcag atcctaagac taatattgac aaggcacgtg
     4621 aaaatatcgg gatggtattc caacacttca accttttccc tcacatgact gttcttgaga
     4681 atattatctt tgctcctgtt gaattaggta aagagtctaa agaagctgct aaaaagcacg
     4741 gcatggcact tctagaaaaa gtcggacttt ctgataaggc cgacgccttc ccaggaagtt
     4801 tatccggcgg gcaaaaacag cgtgtcgcca tcgccagaag tttagccatg aacccagata
     4861 ttatgctctt tgatgaacca acttctgctc ttgaccccga aatggttggg gacgttttga
     4921 acgttatgaa agacttggca gaacaaggca tgaccatgtt aattgttact cacgagatgg
     4981 gatttgctcg ccaagtagct aaccgtgtta tctttacaga cggtggtcaa ttcttggagg
     5041 atggtactcc tgaagagatt tttgatcatc ctaagcaccc tcgtctcatt gaatttttag
     5101 acaaggtctt aaacgtctaa tagagcagac accatactaa cttccaaaaa ataataaggc
     5161 aaggaaacct gtttccttgc cttttttggt tactgttatt attcaaacca gcaaaatagg
     5221 gatactctta tgactctctc cttcataaga gtgtccccta tgctttttta tgggcgttta
     5281 tgtttagtga ggtaataacc taatcccgta agagctagtc ccgtcactat gtgtaagtat
     5341 ttgttaccaa ccatcggact aatggcaatg agaaaaaagc caacagccat taaaaaagtt
     5401 gctccatttt tttctgtcat gcaaggtcac tcgctttttc tttattggcc aaaatgacaa
     5461 atggtgccca gataaggaag gcaacaaaga ggttaaacag tgaaaccaaa cctgccataa
     5521 tattacctcc agtagctagg taagcataaa gtccaacagg ggtaatccaa ggtactgata
     5581 agaataccgg tggaatcaaa cctattgcag tagcaaaata agctatgcta gcacaaattg
     5641 gtggcacaat tagccatgga atcacaaagg ttggattcaa aacaattggc atcccaaatg
     5701 taattggttc gttgatattg aaaacaccca ttggtgcgga caatttggca atggttttat
     5761 gctcttctcg ttttgagaat atgaagatag caataatcaa tgccaaggtt actcctgaac
     5821 cacccatttg agcataagca tcaaaggacc cgcgtgtcca aaggtatggt aaattagcag
     5881 cgctatgcgc tgtattgtag gcagctgtat tttctgttaa agctaccata taaataccat
     5941 ccatcactgg ggctaagaca ttatgaccat gcaagccgaa gaaccagagc agttgaacta
     6001 agaaggttaa caagataact gaaccaatac cctgtgataa gcctagcaat ggtaattgga
     6061 tataggttga aatgacatca cttagggaag aacctgttaa tgcgaagatg aggtaggcga
     6121 aaattgccga agcgtaaatc gcaactgttc ctggaataat ggcagcaaag gctttattaa
     6181 ccgcaggtgg tacattatct ggtaaggtaa tagtaatatt acgtttggtc aaagccgcat
     6241 acacaaaact tgataaaaag ccaataatta aagctgtgaa caagcctgtg gcaccgacat
     6301 actttagagc tattgctccc cattgactag tttcaatact tgaagctcca cccgcagtaa
     6361 cgactgaaag ccccatttct tttaaattgc taattaggtt agcagaggca ttttcaagtg
     6421 gtgtcgaaat ggttaaagtc tgaggtaggg tggcaataaa tgagccaaaa gaaatcaatc
     6481 ctcctgccaa tggattaatc ttatgcataa cagctaaatt gtaaccgaaa gcaaaggcaa
     6541 aaaagagcgc catgatacca attgtcccaa aataaacata gccattgatg tcgataacag
     6601 gttgcatagc ttttgcaaac cctgtccatc ccatattgtt tggaatatcg cgtaaaaaaa
     6661 cgttcaataa gacagcaact gaacctgcca tggtaatagg catcattgaa ataaaggaat
     6721 cacgaatagc tactaaatgc cgttgtgacc caatttttcc tgaaatatcc ataaacttat
     6781 cagaaaaatg cgacataaat cttctcctct ttttattttt ttaatgtaac aaaggtaacc
     6841 ttaaaagcag cggtgtctgc ctaacacaat tatctcaaaa tcatccttgt taaacgtgat
     6901 gcttagagat aaccggtaat cgactcttat ccaaatgaac ccttctctct catccaaggt
     6961 ctgtgaataa tcttcacaaa gacgatggtt gctgcaactg tttagcatat tggataaggg
     7021 ctgctaactg agcttgagat tggcgttcta ggcttttttt gaacagtttg ccaacaataa
     7081 aatgatttgc tttttgaaaa atatctagag gatgatagtc ataagaatag gtaattctag
     7141 tccgattctc ccccagagcc tctaatcgat aagccaattc ctttatccca tgattagaac
     7201 taaaacaagc agtatataat tgcggagctt ctagggccgt aataagcacc ctcactgtac
     7261 gctctttgta tttaccataa tgtttaacat agtttatccc cgctttgata tcatctcttg
     7321 acaaccgtct caaggtattt tgtcgataat cttcttggag cgatatcagc atggcttcaa
     7381 aacaatgatg aatggaaaca tctccttctg ctgaaatgat catgactcac acctctgtat
     7441 tgctgacatt ttgtcgtaaa cggtaaccaa ttccttggct aaatcaataa aggctaaggc
     7501 agtcatcatg tgatcttgcc catgcaccat caataaagac aattcaaccg catcaccagc
     7561 tgcttcttgg gacagcaaat gtgtctgcga tttatgggca atatttaacg agtttgtcgc
     7621 ttcttgaagt aagtgctgag cctcctcaaa ctgcccatct cgtgctgcat gaatagcctc
     7681 tacggccttg cccttggctt cgcctccata catgattaag cccataatag cttctaagtt
     7741 ggatggttcc gtcatgccta ctcctccatc atcgctaggg ctgtttcaag gactttttca
     7801 ccgttcataa gaccataatc agccatgtta atggcatcta ctttaatatc tggttcaaac
     7861 ttatctttaa aatcctttag taagaatttg acttgtggac ctaacaagag aacgtcaatg
     7921 ctattagcag ccacttcgtt gtcagcttca ctcacaggaa ctgcccaaat agaaacttca
     7981 aggtcacgcg cttgggctgc tttttgcatc ttagtcacca acatactagt tgacataccg
     8041 gcattacaaa ctaacataat agatttcata aggtttctcc ttttaatcgt tttaatcatg
     8101 aataagtggg gtaaacactg tcatgaattt ggaataattt ggttcttcta gtaacgtttg
     8161 ctgaagctcc acctgattga caaaagatgc caaacctggt gatacatatt ttaacctatg
     8221 attatgccct ttagacgggg ataatagaaa gacaaaatga acagcttgat gcaccttgtc
     8281 ccactcaaga ggctctcggc aaatagccac tactacctgt tcagaataag tcatgggatt
     8341 agcaggatgc ggaaaggcaa gcacttctcc atagatgact gggctgtaat tttccctcag
     8401 taccatttga tgatagaagt cctctacaaa catttctgtt cccgcctcgt caagacaagc
     8461 aatcatccgt aaaagcaagt cttcctttga gattttctcg tctaaataca gaaaacgatt
     8521 agggctaaaa acacctgtta gaagttgctc tgcttttgct aaactcatct gtgacggtaa
     8581 actgacctct ttcttgatac cttcttgttc tccaataaat tgtcgaatag tttcaatatc
     8641 ctgatttgac aaaaaaacac tgacagtaat cactggtgtt aaaaacatca gattggcaag
     8701 gctgatagag gaaataatca aatcaacggt tttcagtcgc tcttcggtta tttcatagta
     8761 actgataaca tcgacaatac gcaaacgtcc ttcaaattcc ttttccaagc gatttttcaa
     8821 catcatggca ctaccataac ctgtggcaca aactactaga accctcaatt tatgacggtt
     8881 tgaataacgc tcaatggccg ccattaaatg caaactaata taagcccatt catcatctga
     8941 gacatcattc ttttgacata caagcaaatc cgaaaaggtc tgcttggtaa gggtaaatat
     9001 ttcaggatac tggcttttaa tttcctcagt taaaggatta gtcagctgaa tatggttttc
     9061 aagacgtgtg gtcaagggca tcatgtgggc taataaacct tgaaataaat tggtatctgt
     9121 ttctaaagtc atgcctgtca attgactaat cttggcaata catgctttta aatggtcctg
     9181 caacttttca tcggtattat catcttgcca atgcttacca acagaatgtt tgacctttag
     9241 atgcagtgca atataattag cctcctcttt aggaaaacgt atccccatca cttcttccac
     9301 tcgatacaaa atgcgcagag ctacttgata ctcatcagac tgacgaatag ctattggaat
     9361 ggaaaacagt tctaatggac accccgatcg aatacgctga accattaagg caatatgcaa
     9421 gactagatta ttcatgacaa aatcagaaag tttcaactta gcatcccgac attcatccaa
     9481 gacaataatc atgatttctg caaaattaat accttcaaga aagatattac ctaccatggt
     9541 ggacaaggta ttatcaaaac tagtaacaaa aaaatagtcc atgataaaat gcctaatatc
     9601 ctcttcttta cctcttattt gaatatgttg gtgagttatt tcaagctcta actggtaagg
     9661 tattatgcgc tccttaatgc ctgctaaaac atgttttaaa gttgtccgac tgatatacaa
     9721 ttcttgacaa agctcttcaa aatcctgaac ggcatcttca aaaaagaatt tatgaagcac
     9781 ataatcttct cgatcaaccg attcttccac ttgagacaca tctgccaaac gttttttaga
     9841 cgtcacactt tcttgccaaa agatgtcaaa tgccatagaa tggtcaattt ctaagcagta
     9901 acctcgacct tgtttagaaa tgatgtgagc tccgtgttca ggaaggctac tgatcagttc
     9961 tttgaggtat ttcctaaccg tacggtcact cataccaata acctcagcca gagttgcact
    10021 agagacaaac tgctctttgt gatggattag aaatgttatg atggccagtt ctttttttga
    10081 taacattagt cctccttact actttagaaa acgctttcta ccctctttta gtgtaccaaa
    10141 tatttcctga aaaaggtgac catcattttc cgcattgatt gtgaaaagaa tctatgatgg
    10201 gtcaatctcc aaacaaaatt cctgccaagg tcgcaaatca tctaacaaac taagatagtc
    10261 ctctctgacc tcagcaacca cattagcttt tgaactaacc gtaaaatttt tcaaagcaat
    10321 ttgcagttct cccttatatc gatgatagcg gtcattgtca ataataatgc aacctcgttt
    10381 gacctcctta gattggtctc ttggagcaat cgattcctga gcataaacta gacgtggcat
    10441 ggttgatcga atcacataat cagatacatc gccacgataa caatgcggat agccaatgat
    10501 ttgctcctca acttctgtca aatcgatgat aggcctaacc ttgatcgttg tgactggtct
    10561 tgctaaagcc tgagtacatg ctgccaattc ttcttccgaa atgaattggt tagatatgag
    10621 gatattatca atggttccta tcgctttcat taattctact tgcaggccaa tgggcaagtg
    10681 cctatggtct tccactgtcg gcaagccttc tgccagtagc caagggcctt cagatgctga
    10741 ctgagcggta ataaaagcag ccgtttcaat atcatgctca tgataaaaac gtgacatatc
    10801 cttaaaatgt tgccatgaca aaccggtaaa ttcatgtgga taaaaattat ggcaaccaat
    10861 aatattgctc cgttctgcat ctgtcgctag caatgacatc aataattgtt tatcagtgct
    10921 catattaagt tcaattttaa gcccaaaggg atttcttgtt aaagttacaa tctctgctag
    10981 agggagagcc tcgtctaagc gtaagcccgc taacccgaag gcatgagctc gttcaataag
    11041 ctgatctgac caaccagctt ggctaataaa gcttggacta acgtcagcaa tcactcgaat
    11101 gcctaattga tttgcataag caatgagctc tgcgtagcaa tgaaacatct ggtgatcagc
    11161 tggtgccagc tgtaagaggc tcataaacaa gcgcttggct ccatagctat gacataagtc
    11221 aatataagct ttactcttgg taacatcata ccgctcaggg tatagagaaa atcctaaatc
    11281 aaccatattg cctcctattt atcaaaacca tttgactcgc tcaacgcctt aaaccagtaa
    11341 cctgattttt ttatggttcg cttttgactc tctaaatcca aagctaccaa accatatcgg
    11401 tttttataag catttaacca agaccagcaa tcaataaaag tccacaagag gtagcctttg
    11461 cagttggctc cttctcccaa agccttatga agctggataa gatgatcctc gataaaggtg
    11521 atgcggtagt catcttgtat ctggccatct gctaaaaaag cttcttcacc ttcgacaccc
    11581 ataccatttt ccgtgactag ccattcgatg ttaccatagt gttcttttaa attaagggca
    11641 atatcataaa gtcctggttc ataaatttcc caaccccggt gaggattgac ttttttacca
    11701 ggcatatcat aaggttcaaa ataaatatct aagataaggg ggttcccctc ttgctgtgac
    11761 ttactaggtg cctgaacccg caaaggctga taataattaa ctcccaaaaa atcaacagta
    11821 ttgtttttga taatctctaa ttcatcagca ctatattgag gtaataaatc agcttcctct
    11881 aaaatggaaa ctaactctgc tgggtaaaca cccaaaactg atggatctag gaaggatttg
    11941 gtttggaaaa gctctgcgat tctagcagcc ttgacatctt caggagcatc actccgagga
    12001 taagcaggtg tcatgttaag cacaatacta atcttgtggt cgggatgaag cttatgacaa
    12061 gctttgaccg ccagtgaact ggccagttgt gtgttgtaag ccacttgaac tgctgccttg
    12121 gcatctactt tacaagggta gtgataataa cctaaatagc cacattcgac tggaacaatc
    12181 ggttcattaa aggtaatcca agtgtttact aaatcaccaa aaagctcaaa acaggttttt
    12241 gcgtaggttt cataagccca gacagtagct ttgttttccc agccaccttt ttcttgcaag
    12301 gcatagggga ggtcaaaatg atagaggtta acaatcaatt taataccttg agcaataatg
    12361 tcttgaaata cttctcggta aaatgtcacc gcctttggat taacctcccc gactccttct
    12421 ggaatcaatc gagaccactg gattgaggtc cgaaaaatcg tgtggcctgt ttctttcaaa
    12481 agggcaatgt cacccttata gttttcataa aaggttgagg ttttttctgg accaatttgg
    12541 tgatgaaact tagctgactc aatactaaac cagtaatccc agttgctagg tcctttgcca
    12601 tctccaggaa ccgttccttc gctttgaggc ccagatgtgg aacttcccca taaaaagcca
    12661 tctggaaatt gataacggtg ttttctttgt ttcatatcct ttgtcctttc tttgctcact
    12721 tctcttttta ttataagaag aaaaacaggt gatgtaaacg ctttaaaaaa tctgtttttt
    12781 ccttatcatc acggaaaata agtgatttaa agcttgacat attttattat cttaaagagc
    12841 ctatctaacc tgccctgcta cttcttatca aaaccaagcc cctattgaca gatgccttag
    12901 cctatgtttg aataggggta tggcttattt aaactacttt acaaaaaccg agtgggcact
    12961 ttggttaagc tctgtcttgg ccattttaat tagcgccctt ttattcggta agcaagctcc
    13021 cttagcttta atagcttctt tgattggtgt gacctctctc atttttagtg ctaaagctaa
    13081 tcctattggt caagggctcg tcattatttt ttccattatc tatgcctatc tttcattacg
    13141 aaacagttac tatggagagt taatgaccta tcttttcatg accctcccta tgactatttt
    13201 ttcacttttt acttggttaa accatccttt tgaagggaaa aaatcacaag tgactatttc
    13261 acgattaaca cccactgatc gaagatgtct tttcgttttt actatactgg tcactcttat
    13321 tttctacggc atcttggctt ctattcaaac agcctattta cttgtctcca ctttatcgat
    13381 tgccacttct ttctcagccg tttatctcag ctataagcga agcccttatt ttgctttggc
    13441 ttatggactc aatgatctag tcctcatcct cttatggatg catgctgctc aaacagatgc
    13501 cagccaatat gctgtggtca tctgctttgc cacctttctt attaatgata gttacacttt
    13561 ttatagttgg ctaatgctcc aacgttacca agaaaaaaag gtcaaaaaag gatgagggcc
    13621 taagcctcat cctttttcaa tttttcacgt tctaagcgca aacgtctatt gggatttaaa
    13681 agattaaaca attcttctaa tttctcagca ttccaaacat ctgctgccga tacaaaattt
    13741 ccatccttat ccttaaagga tatcggttta tcacccataa tcagaaacct ccatcttaaa
    13801 gataaaacac aaggctgcta tggcaatgcc atttctaaag accacattaa tccacaaatt
    13861 caaattcaaa tttaccaata cgaacaagat ccccgtcttt tgctccacgt tcacgaaggg
    13921 cttcgtcaac ccccataccg cgcaattgac gggcaaattt catgatggat tcgtcacgtt
    13981 ccatattggt catgacaaag agacgttcta acttctcacc agacaagacc caagtagcgt
    14041 catcgtcacg tgtgatctca aattctttct cagcctcagc aaaaccatag taagcttcct
    14101 cgtccaccag atcagattca tcatacaata agaattcatc cgtcttagca agtaattctg
    14161 ccgttgcttc taacaagttc tctaagcctt gatgtgctag gcttgaaata gggaaaatca
    14221 ttggcaaatc atcaaactcg tcatattggg cagccaattt tttcttgaag gctttcaagt
    14281 tttcttgagc ctctggcatg tccattttat tagccacaat aatctgtggg cgctccatca
    14341 atcgcaaatt ataggtttcc agctcgttat taatagaaac ataatcttcg taaggatcac
    14401 gaccctcact agcagacatg tcaatcacat gaagaataac ccgtgtccgc tcgatatgac
    14461 ggaggaattg agttcccaaa ccaacccctt ggctagcacc ttcaatcaaa cctggcagat
    14521 ctgccatagc aaagctatca cctgactttg tacgaaccat tccaagatta ggaacaatag
    14581 tggtaaaatg ataggcacca attttcggtt tagctgatga cacaacactt aacaaggttg
    14641 atttcccaac agatgggaat ccgaccaagc caacgtcagc taagattttg agttctaact
    14701 ctaactgacg ttcctcacct ggctcaccat tttcagcaat ctctggcgca ggattacgag
    14761 gagttgcaaa acggatattc ccacggccac cacgaccacc cttagcaatg accacttctt
    14821 gaccatgttc tactaagtct gtaattactt ttccagtttc agcatcacga accgttgtcc
    14881 cttgaggaac aaaaacaatc aaatcttctg caccacggcc gtgcatgcct ttggtcatac
    14941 ctttttcacc agatttcgcc ttgaatttac gattatagcg gaaatccatc aaggtacgca
    15001 aaccttcgtc cactcggaag ataactgagc cacctttacc gccgtctcct ccccaaggac
    15061 cgccatttgg gacgtacttt tcacgacgaa aagctaccat accatcgcca ccacggcctg
    15121 cttggacact gatttttgcc gtatctaaaa acatactcat acttttttta ttctctaact
    15181 ttcttttact ttaaaaaaac gcctttcagc gtttccttac attaatactg atagggcact
    15241 cgcaataagc ccgccaacag ttacaagaac cattaggata acaacgacca ttgtcacttt
    15301 ttcaaaggtt gtttttttgc gaggtccatt ttctccaaat gccacgttaa atacctcatc
    15361 tattgatttt tcttcttata tcttaacatg aaagatcgtt ttaggcaaat accagatgaa
    15421 tatttacgct atgtaggcta ttactgagta ttgtatcttg tgaatttcat atgaatatga
    15481 tacattagca tttgcaaaat aatgttacag ataaaaacct cctcgtctg
//
LOCUS       DAUGOH010000037        15351 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUGOH010000037 DAUGOH010000000
VERSION     DAUGOH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15351
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.037"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            85..333
                     /locus_tag="VH957_001341"
     CDS             85..333
                     /locus_tag="VH957_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8559246.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            370..981
                     /gene="amaP"
                     /locus_tag="VH957_001342"
     CDS             370..981
                     /gene="amaP"
                     /locus_tag="VH957_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEQ8559247.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            992..1180
                     /locus_tag="VH957_001343"
     CDS             992..1180
                     /locus_tag="VH957_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEQ8559248.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1193..1732
                     /locus_tag="VH957_001344"
     CDS             1193..1732
                     /locus_tag="VH957_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8559249.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1773..1973
                     /locus_tag="VH957_001345"
     CDS             1773..1973
                     /locus_tag="VH957_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8559250.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            1984..2472
                     /locus_tag="VH957_001346"
     CDS             1984..2472
                     /locus_tag="VH957_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8559251.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTNAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2635..3276
                     /locus_tag="VH957_001347"
     CDS             2635..3276
                     /locus_tag="VH957_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8559252.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3419..3961)
                     /locus_tag="VH957_001348"
     CDS             complement(3419..3961)
                     /locus_tag="VH957_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8559253.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKTVTLDN"
     gene            4079..4780
                     /locus_tag="VH957_001349"
     CDS             4079..4780
                     /locus_tag="VH957_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559254.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEIDKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHCTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4795..7431
                     /locus_tag="VH957_001350"
     CDS             4795..7431
                     /locus_tag="VH957_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8559255.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMGLGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEVSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSTTSLSPYFNLLDC
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSIQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7523..8119
                     /locus_tag="VH957_001351"
     CDS             7523..8119
                     /locus_tag="VH957_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8559256.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLVNL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8130..9086
                     /locus_tag="VH957_001352"
     CDS             8130..9086
                     /locus_tag="VH957_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8559257.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVSTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9183..10523
                     /locus_tag="VH957_001353"
     CDS             9183..10523
                     /locus_tag="VH957_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEQ8559258.1"
                     /translation="MNEIKCPHCHTLFTINKSEYSQLLEQVRGQAFDEELQKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFAKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALVKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10639..11523
                     /gene="truB"
                     /locus_tag="VH957_001354"
     CDS             10639..11523
                     /gene="truB"
                     /locus_tag="VH957_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEQ8559259.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISQFERTSPLNFT
                     EDDLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11552..12484
                     /locus_tag="VH957_001355"
     CDS             11552..12484
                     /locus_tag="VH957_001355"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEQ8559260.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12527..12931
                     /locus_tag="VH957_001356"
     CDS             12527..12931
                     /locus_tag="VH957_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEQ8559261.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            12933..13211
                     /locus_tag="VH957_001357"
     CDS             12933..13211
                     /locus_tag="VH957_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEQ8559262.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSIYQVVKKAKAIEKGFFSLGN"
     gene            13201..13989
                     /locus_tag="VH957_001358"
     CDS             13201..13989
                     /locus_tag="VH957_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEQ8559263.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVILEDQ"
     gene            13992..15302
                     /locus_tag="VH957_001359"
     CDS             13992..15302
                     /locus_tag="VH957_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEQ8559264.1"
                     /translation="MMSLPKEFINIYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKESRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKSDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
BASE COUNT         4942 a         2530 c         3191 g         4688 t
ORIGIN      
        1 attaaaagac tattgcttga agaataacag ctgttattct tccttggaca aaaggtacag
       61 gagtatctaa aaaggagaat tatcatggga cttatttgga ctttaatcgt cggtgcgctt
      121 attggtgtga ttgctggagc acttactaaa aaaggtggtt caatgggctg gattgcaaac
      181 atcgctgctg gtctagttgg ttcttccgtt ggtcaagctt tacttggttc atggggccct
      241 tctttagcag gaatgtcttt gatcccgtca gttattggtg ccgttatcgt tgttatgatc
      301 acttcttttg tactaaacaa aactaacaac tagtttcctc tttatttagt aagtacttac
      361 aaatagagaa tgttaagtag aaaagaggtc tgtatgtcaa aattgttaaa gattagttat
      421 tgtcttgtcg gacttgttct attgtctgtt tttggatggg tagttggaat aaccggaggc
      481 tatatatatt taccttatag ttatcgttgg ctaagttggg gtatggatag ttttcccaat
      541 ctcttagatt cagctttatc ctattattac ttctggacag cccttgtatt atttgttata
      601 acatttcttg ccttattagt tattatttta tacccaagaa tttatactga ggtccagtta
      661 cgccataaaa ataaaaaagg aacactttta ttaaaaaaat cggctattga aagttatgtt
      721 gcgaccgcta ttcaaactgc aggtttgatg ccaaacccaa cagtcacagc taaattatat
      781 aagcggaagt ttaagattat cgttaaagga cgtttagctt ctcgtgtagc agtggcagat
      841 caaattagtg gcgtgaaaga agggatcgaa aaaggtttaa ctgagttctt cggaattaat
      901 tatcctgtta atttcaaagt ttatgttaaa gatattgctg attctgatcg taaacatatt
      961 accagaaatc gtgtagaata ggagatctat catggaattt tatgaaaaat tcaagtaccc
     1021 tattattggt ggcttggtgg ggctaattat tgccatattg ctcatggctt ttggtttatt
     1081 caaaacgcta ctagcaatta ttttcattat tttaggaata tatggtggcc tgtatgccaa
     1141 aaaaacaggt attattgatc aatttcttaa tcgcaaataa aggagactta ttatgactga
     1201 aacttatatt aaaaacacat ctaaagactt aacttcagca attcgtggtc aattaacata
     1261 tgatgataaa gtaattgaaa aaattgttgg tttagcactt gaaaatgtcg atgggttact
     1321 gggtgtaaat ggtggttttt ttgctaacct aaaagataaa ttagtaaaca ccgaatctgt
     1381 acgtgatggc gtgaacgtgg aagttggaaa aaaacaagtt gccgttgatc ttgatattgt
     1441 cgctgaatat caaaagcatg tgccgactat ttatgactct attaaatcga tcgttgaaga
     1501 agaagtgaag agaatgaccg atctggatgt gattgaagtt aatgttaaag tagtcgacat
     1561 taaaacaaaa gaacaatttg aagctgaaaa agtaagttta caagacaaag tttcagacat
     1621 ggcacgttca acatctgaat ttacgagtca tcaagttgag aatgttaaag cttcagtgga
     1681 taacggtgtt gaaaaacttc aagatcaaaa agctgagcca cgtgtaaaat aattatatgt
     1741 cgtcaattag gtaagctaaa ggagggttta ttgtgtcaga tgaaaaatat aatgcgaaat
     1801 tagatcaagc tggtggcaag ttaaaagaag gatttggtaa gatttctgga gataaatctt
     1861 tagaaactga aggtaaagta gataaagtta ctggaaaagt taaagaggtt attgcagacg
     1921 ccaaagatac tgtaaaagga ttagctaaag gcttagataa taaagataaa taaaggggac
     1981 atgatggaaa aaactcaaat taaaagcact cttacttatg acgataaggt catcgaaaaa
     2041 attgtcggtc atgctttgga aaacgttggc ggattactag ctgtaacagg tggatttttc
     2101 tcaaatatta aaaataattt ggtgaattct gagtctgtaa ctgatggtgt ttcagttgaa
     2161 gttggtagca aggaagtagc agttgattta gcaatcattg tagaatacgg taaagatatt
     2221 cctgctattg cagaatctat taaagctatt gtttctcaaa acgttgatag tatgacacat
     2281 ttgaaagttg ttgaagtcaa tgtgaacgtt gttgatattc gtactaagga agaacatgaa
     2341 gctgctagcg ttactgttca agatcgtgtc actaatgcag cttcaagtac ttcacaattt
     2401 gtatcagaac aaacggaaaa attaaaagat actatctctg atactgtaaa tagtgatgag
     2461 gcagctaaat aagcaatcgt ctaggaagta ttattgacta gtggtgataa gtttgagctg
     2521 gtatttacca gctctttttg tcacggttaa aaagacacgg actattgtca tctctctaaa
     2581 aatatgattt aattagatag aaatttttca aattgttaga aaggagtaaa ttaagtgata
     2641 agtcctaaaa aagagataac aagttcaaaa tatcaaaaaa ttgctatttc agtagctcag
     2701 cgtatcgcaa atggcgaata tgaagtgggc gaaaagttaa agtcaagaac tactatcgcc
     2761 tcgacattta atgtatcacc agaaacggct cgtaaaggcc tgaatatttt agctgacttg
     2821 aaaattttga ctttaaaaca tggtagtgga gctattgtgc tgtcaaaaga aagagctatt
     2881 gagtttataa atcaatacga atcaacccat tccatcgctg ttttaaaaga aaaaatacgt
     2941 gagactatta atgatcaggg aaaagcaatg gaaaaaatgg ctgttttggt caatgatttt
     3001 ttaatgcaaa gtcaatctgt tagtaagcaa tacccattag caccttatga gattatttgt
     3061 agtcaagatt cggaacattt tggcaaatct attggtgtgt taaatatctg gcaccagaca
     3121 ggagcaacta tcgtcgctat tgaacatgct ggtcagttta tcgtttcacc aggtccttat
     3181 tctgttattg aaaaaggcga tcatatttat ttcgttggtg atgagtcagt catttcacga
     3241 atgaagacct tttttaattt acgaaaagga ttataagttt gagggcccac ctcaaacttt
     3301 ttttgttgct gttgagcatt attaaaagag gcagatcatc atggtttgtc tttccaaaat
     3361 atctgtttag acagttgttt tggattggga gcatgatttc agactctttt gatgtttttt
     3421 aattgtctag agtaactgtt ttgagaataa tatcggcaac ttcttcagtg gtttcttgat
     3481 agccattagc aatccaatag ctgataatgc tctcaatact ggcaaggtaa acttctaaag
     3541 catagggata aggaatatgg tattgattgg tcacaatgtc ttggaaacca gtaatagtag
     3601 tcaaaaattg gtaacagaaa tccttgatga gttgcggaaa tttgaggtaa gaaatagtag
     3661 cgagtgcggt tataaattct ctatgttcta taaggtagga caaggtttga ttgaggactt
     3721 gtcgagtgtc tgtgtagatt tcagcctggt ttaacaaacg gtacaaatca tccagagtgt
     3781 catttttgaa gtgattcatc atgtcaaatt tatcagtgta gtggaggtag aaggttcctc
     3841 tattgatacc agccttttta gtaaggtcag agacagtaag agtttcaaaa gattgttcag
     3901 ttagtaaggt ggttaaggcg gtctttacat aagctttggt ttcagtatgt cttttggtca
     3961 ttctcaggtg ctccttaaat caacagttgc gtcagatttg ttcttgttaa atacttaggg
     4021 ccattatata ataaggctat aattaaatca acactatgtt caaataatgg aggggcagat
     4081 ggcttttatt gaattaaaac aggtttcaaa atcttatcag gtaggagaga cgactgtttt
     4141 tgccaaccac gaagtgtctt ttgagattga taaaggagag ctggtggtta ttttgggagc
     4201 atccggagct ggtaaatcga cagtcctcaa tattttgggg ggcatggaca cagtagatgc
     4261 aggtcaagta attattgatg gcaaagacat tgctcattgc acatctaagg ccttaactca
     4321 gtatcgtcgg aatgctattg gtttcgtttt tcaattttat aatttggttc ctaatttgac
     4381 agctaaagaa aatgttgaat tagcagttga aattgtagca gatgctttag atcctgtgac
     4441 cattttaaag gaagtaggac tcagtcatcg tctggatcat tttcctgctc agctctcagg
     4501 tggtgaacag caacgggttt cgatagcacg tgccttagct aaaaacccta aattgcttct
     4561 ttgtgatgaa cctacaggtg cccttgacta ccaaacagga aagcaaattc taaccctctt
     4621 acaggatatg gcacgaacta aggggaccac ggtagttatt gtaacccaca atgctgctat
     4681 tgctccgata gctgatcgtg tcatttttat gcatgatgca caggttacca agacagtcat
     4741 taataaggaa cctgcaagca ttgagacaat tgattattaa gaggaaggtg tcgtatgata
     4801 aagaaaacct tatggaagga tattttgaga gctatcaaga atagtaaagg gcgattcatt
     4861 tccttatttt tcctaatggg cttaggctcc tttgctttag ttggacttaa agtcaccggt
     4921 ccagatatgg aacgaacagc cagccgttac ctcgaaagac accaggtgat ggacctaacg
     4981 gtactggctt ctcatcaatt ttcccaagcc gataaacaag agttagatac gttaaaaggg
     5041 gctcatttag aatatggtca tttacttgat gtcagtctaa ctagcaacca gaaatctctt
     5101 aggctctata gcgtgccaaa gaaagtgtct aagccagtct tggttaaagg gagttggcca
     5161 aagcgagaga cagatttggt tttatcctcc tcacttgcta aaaactatca gattggagat
     5221 gaactagcag tcacctcacc tatggaaggt ttgctgacga caacccattt tcaagtggtt
     5281 ggttttgcga attcttcaga agtttggtcc aagtccaatt taggaagttc ctcaaccgga
     5341 gatggaagtc tctacgctta tgcttttgtt aatccaaacg tttttaaaag tgcctttaac
     5401 ctgctgcgca tccgttttag taatcttcgt ctgacaaacg ctttttccaa agactatcaa
     5461 aaaagggtaa cccaaaacca agctcatttg gataatctac ttaaagataa tggccagaag
     5521 cgttatgatg acctccaaaa tcagtatgac cttgccttaa aaaatggcag agcagcactt
     5581 gcaaaggaaa cagtgaaact agctgcgagt gaggagaact taactttttt agaagtctct
     5641 gctttacaag aagctaagca tcagattgaa caaggcaaac aagcattagc caaggaggaa
     5701 aagcagttag agcaggtgca ggctacaaaa gataagctag aaaaacccag ttacctgact
     5761 tataatcgct cgaccctacc aggaggagaa ggatatcata cttatgcaac ttcaacgacc
     5821 tccatttcaa atgttggaaa tatttttcct gttgttcttt atctcgtagc tgctctagta
     5881 gcctttacca ccatgacacg ttatgttgat gaagaaagaa caagctctgg tctattaaaa
     5941 gccattggtt attctaacaa ggatatcagt ttaaagtttc ttatctatgg gcttttagcc
     6001 agttttttag ggacaacttt aggtattatt gggggaactt acctcttatc tgccttgatt
     6061 tcagagatct taacaggagc tttgactatt ggaaagactc acctttatag ttattggttt
     6121 tataatggca tagcttactt gctggctatg ttatctgctg ttttaccagc ctacttaatt
     6181 gtcaaaaagg aattattcct caatgcagct cagttattgc tgcccaaacc tcctagtaag
     6241 ggggcaaaaa tctggttgga acaccttact tttgtctgga aagctctgtc ctttactcac
     6301 aaggtgacca tacgtaatat ttttcgctat aaacaaagaa tgctgatgac cattgtaggc
     6361 gttgcaggct ctgtagccct tttatttgca ggcttaggga ttcagtcgtc attagccaaa
     6421 gtagttgagc atcaatttgg tgatttaacg acttatgata ttttggctgt cggttcggcc
     6481 aaagcgacag cgacagagca aactgactta gctagctatc ttaaacaaga acctattaca
     6541 gggtaccaaa aggtatctta tgccagctta acccttcctg taaagggatt acctgataag
     6601 caaagtattt ccattttatc aagttcaact acctctctta gcccttattt taatctgctg
     6661 gattgtcagg agcaaaagaa ggttcccatt ccaacctctg gtgttttgat ttctgagaaa
     6721 ttagcctctt attacaaggt aaaaccaggt gatcagttgg tattgactga tcggaaagga
     6781 cagtcttata aagtgacgat taaacaggtt attgacatga cagttggcca ttacctgata
     6841 atgtctaata cctattttaa gaatcatttt aaaggattgg aggctgctcc tgcctatctg
     6901 attaaggtaa aagacaaaga tagcaagcac ataaaggaga cagccagtga cttgttaacc
     6961 ttaaaagcga ttagagcagt ttcacaaaac gtcaatcata ttaaatctat tcagctagta
     7021 gtcacctctc ttaatcaggt catgaccctc cttgtcttct tgtctatttt attagcaatc
     7081 gttatccttt ataacttaac gactattaat attgctgagc gtattcgaga attatccact
     7141 attaaagttc tgggatttta cgatcaggag gtcaccttat atatttatcg agaaactatt
     7201 tcgctatccc tagtaggcat tcttttaggt atctatttag gaaaaggcct gcatacttat
     7261 atcatgacaa tgatttcaac tggggatatt caatttggtg taaaggttga tgcttatgtt
     7321 tatctagtgc caattctagt aatccttagc ttgttagcgg tattaggtat ctgggttaat
     7381 cgccatttaa aaaaggttga tatgttagaa gctttgaaat ccatagattg attggtgaaa
     7441 agacagatat agacagcact tgaaaagtta atcatattat gatagtatct aaatactata
     7501 atttaataga aagatactat gtatggaaaa tagcattgag gcctatctag cagatagcag
     7561 agaaaaggta acattaggta cagttgttga ttgttttaaa ggaaaagcag tctcaagtaa
     7621 ggttgtgcca ggtgatgtgg gattggttaa tttatctgac atgggcacct tagggattca
     7681 atatcaccaa ttaagaactt tccagatgga tcgtaggcag ctcttgcgtt accttttgga
     7741 agacggagat gtcttaatcg cctctaaggg aaccctaaaa aaagtctgtg tttttcataa
     7801 gcaaaatcga gatgtggtgg catcatcaaa tatcactgtc ttacgccctc aaaaactgtt
     7861 aaggggctac tatatcaagt tctttttgga ctcacctatt ggtcaagcgc tcttggacgc
     7921 agcggaccat ggcaaagatg tgatcaatct ctcaacgaaa gaattgttgg atattccaat
     7981 tcccgttatt cctttagtga aacaggacta tttgattaat cactacttga gaggattaac
     8041 agattatcat cgtaaactca atcgagcaga acaggagtgg gaatatattc agaatgaaat
     8101 tcaaaaagga ttaggttagg agtcttgtca tgggttcagt tgaacgtaca ttaaaaatga
     8161 ccttggctac cattgttgcc attttaattg cttaccaact tcatctggat tatgcaatgt
     8221 cagcggggat cattgccctg ttaagtgttt tagacacccg taagtccagt ttggtggtcg
     8281 ctaggaatcg cttgctatct tttttcctgg ctttcgggat tgcgatgatg tgctttagct
     8341 tgtttggttt tacgacagta ggttttatgt gttatttgtt aattattatt cctttgctct
     8401 atcactttca gatagaggca ggactggttc ctataacagt acttgtgaca catttgattg
     8461 ctaaaaagag tattgcatta cctattttat cgaatgagtt tatgctcttt tttgtaggga
     8521 ctagtgtcgc tttactattt aatgcttata tgggtccaca agatcagcaa attcggtact
     8581 atcaccaaaa agttgaatcg gatctgaaag gtatcttata ccgttttgaa agttttctac
     8641 tggaaggaaa aggtcaaaat gaagggctct tgatcaaaaa ccttgataaa atattagatg
     8701 aagctctaaa actagtttat cgagaaaggc ataatcaact atttcagcag accaattatc
     8761 aagttcatta ttttgagatg cgacgacaac aaaatagact attgggacaa atggctatca
     8821 acgtaagcac gttaatgaga caaagtaagg aaagtattct tttgtcacat ctttttcacg
     8881 aaactgcttg tcagctaagc gaacaaaatc cggctttaac cttgattgat gacatcgaac
     8941 aattgcttga aacctttcgt catggtgatc ttcctcaaac tcgggaggaa tttgagcgac
     9001 gtgcggtttt atttcagctc ttacaagact tggaacgttt tatcttatta aaggtagagt
     9061 tttatcagga ttatcaaaat gactaaatct ctattgcaca cttcttatct atgacagctt
     9121 gggacttaac ttcctgagct tttttgctat aataaaaaca agaatctcag aatggagaca
     9181 agatgaacga aataaaatgc cctcattgtc ataccctatt tactatcaat aagtcagagt
     9241 atagtcaatt attggaacaa gtcagagggc aagcctttga tgaagaattg caaaaacggc
     9301 taatcaatga gatagccttg ctagaagaaa aagcgaagca tcaattgcat gaggttgtcg
     9361 caaaaaaaga aacagctatt accagcttga caaaccaatt agagcaaatt gaaaaagaac
     9421 aagcctacct cagacaagaa gaactggcta aaaaagacca gcttattgct tctttagaag
     9481 cgaaacttga taaattagcc tcgcaaaatg ctttggaact ggccaatcaa ttagctgaga
     9541 aggacaaaga agtggttagt ttgaccaatc agctggacaa attagcactt gaaaaagatg
     9601 ccacgttcca gtcaaagctt gctacaatcg aaaaagaacg cgatggaatc aaaaaccaat
     9661 tggcgcttca agctaaagaa agtgaattgt cgttggcttc ggtgcgcagc gactacgaag
     9721 cacagttaaa agcggctaac gagcaagttg aattttataa aaatttcaaa gcgcagcaat
     9781 ctaccaaagc aatcggagag agtctagaac tctatgctga aacagagttt aacaaagtaa
     9841 gaagctatgc ttttccgaat gctagctttg ccaaagataa ccaattgtct agtcgtgggt
     9901 caaaagggga ctatatttac cgagaggttg atgccaatgg tgtagaaatc ctctctatca
     9961 tgtttgagat gaagaacgag gcagacacca ccaaaacaaa acataaaaat agtgattttt
    10021 tcaaggagtt agataaagac cgtcgcgaaa aagattgtga gtatgctgtt ttggtaagca
    10081 tgttagaagc tgataatgat tactacaata cagggattgt tgatgtcagt catgagtatc
    10141 aaaagatgta tgtggttcgt cctcaactct ttattcagtt gatagggatt ctgcgaaatg
    10201 cggccctgaa tagtttacat tataagcaag agttggcctt ggttaaggaa caaaatattg
    10261 acatcactca cttcgaagag gatttggacc aatttaagaa tgcctttgct aagaactatc
    10321 agtctgccag caacaacttt aaaaaggcta ttgacgagat tgataaatcg attaaacgca
    10381 tggaggaagt gaaacgcttt ttaaccacta gtgaaaatca gttacgctta gctaataata
    10441 aattagagga tgtttcagtt aaaaaactga cccgccaaaa cccaaccatg cgagagaaat
    10501 ttgaagccct caaggaccag taagcctgaa agtgagtctt tccttgctaa aattggttaa
    10561 gcgtttattt tggcaaaact gatgataaag cggtagaata gaatcagtaa caattactaa
    10621 ttagagagaa aaatagacat gataaatgga atcattaatt taaaaaaaga agccggtatg
    10681 acctctcatg acgcagtttt taaattacgg aagttattac aagaaaaaaa gattggacat
    10741 ggggggacct tagatcctga tgtggtcggt gttctaccaa ttgcagttgg taaggctact
    10801 cgtgtgatcg aatacatgac agaagctggc aaagtttatg aaggacaagt gactctcggt
    10861 tactcaacaa cgactgagga tgctagtgga gaggtagttg cgaggtcctc tttgccagct
    10921 gtgctaacag aagaactcgt tgatcaaacg atgacgactt tccttgggaa aatcacacag
    10981 accccaccta tgtattcagc cgtaaaggtt aatggccgta aattatacga gtatgcgcgt
    11041 gctggtgaaa gtgtggaacg tcctagaaga gaagtgacca tttcccaatt tgaacgcacc
    11101 agccctttga attttactga agacgatctc tgccgattct cttttaaagt tgcttgtagc
    11161 aagggaactt atgtgcggac cttagcagtt gatttaggtc gagctctagg ggtagagagt
    11221 catatgtcct tcttgcagcg atcagcttca gcaggattaa ccctcgagac tgcctatact
    11281 ttgggagaaa ttgctgatat ggtttctaaa caagagatgt cttttttgtt accgatcgag
    11341 tatggcgttg ctgatcttcc taaaatggtt attgatgata ctgaattgac tgaaatttca
    11401 tttggtcgcc gtcttagtct ccctagtcaa gagccactgt tagctgcttt tcatggcgaa
    11461 aaagtaattg ctattttaga aaaaagagat caagaataca aacccaaaaa agttcttatt
    11521 taaatagttt gagtaagtag aatggataat tatggaaatt gaatatatca aagattatcg
    11581 tgatattaac caagaagatg atacagtctt ggtattggga tattttgatg gattacaccg
    11641 tggtcataaa gccttatttg acaaagcaag agaggttgca aataaagaag ggttaaaagt
    11701 agtcgttttt acgtttacag agtctccgaa attggctttt tcgcgttttt ctcctgaatt
    11761 attgcttcat attacttatc caaagaagcg ttatgaaaaa tttgccgatt acggtgtaaa
    11821 taaattatat ttggttgatt ttacttctaa attctctaag gtctcatctg atcattttat
    11881 aactcattat attaaaaacc tgaaagcaaa gcatattgtt gtcggttttg actataagtt
    11941 tgggcataat cgtacagata gtgattattt aaccagaaat tttgaaggac aagtttatac
    12001 cattgaggaa ataaaagaag atcatcgaaa aatttctgct acatggataa ggaagcttat
    12061 tcaagaaggt aatgtagtta aagcaaacca cttgttaggc tatgacttat cgacaagggg
    12121 gagagtcgtt cacggggatg cgcgtggccg tactattggt ttcccaacag ccaatctagc
    12181 tccaattgac aacacatact taccagctga tggagtctat gttacaaatg ttattgttgc
    12241 taataaaatc tatcgctcta tgacgagttt aggtaaaaat gtgacatttg gggggaaaga
    12301 gttgcgtcta gaagttaaca tttttgactt tgacgaagag atctatggag aaattattga
    12361 gattgtttgg ttagataaga ttcgagacat ggaaaaattc gagggaatcg aagatttgac
    12421 tgatagattg gaatatgata aacgaacagc attaaattgg aaaaaagata gcaaattatc
    12481 ttaaattttt gtataataag gtaagtaaat ttgatagagg aaaaatatgg ttaccttatt
    12541 tttatcacct agctgtacca gttgtcgtaa agcaagggca tggttagtaa aacacgaagt
    12601 tgactttcaa gagcataata ttattacaag tccattaagc cgtgatgaat taatgtcaat
    12661 cctctctttt acagagaatg gaacggagga tattatttca acacgttcaa aggtttttca
    12721 aaaacttgat attgatgtag aagagctttc aatttcagat ttaattgatt taattgctaa
    12781 aaatccaagt cttcttcgtc gccctattat catggatcaa aaacgcatgc aaattggttt
    12841 taatgaagat gaaattagag cgtttttatc gagagattat cgcaagcaag aactacgtca
    12901 agcaacgata aaagcagaaa ttgaggggtg atatgtcagg taattattat tatccacttg
    12961 acttaagttg gagcactgaa gaaatatcct cagtgcttca ttttttgaat aaagtggaat
    13021 tagcatatga aaaaaaagta gatgcaaaac aactactaga tagttataag acttataaaa
    13081 ccattgtcaa aagtaaagct caggaaaagc aaatcgaccg tgattttcaa aaagttagtg
    13141 gttattcgat ctatcaagtt gttaaaaaag cgaaggcaat tgagaaagga ttcttttccc
    13201 ttggaaacta aatacgcatt tgcaaggcaa atcattaaag aagcagggct ttttatcaag
    13261 tcaaaaatgt cagagcagct agatattcag gtgaaaacac aatttgatga tctggttacc
    13321 aatgttgatc aagaaactca acagttactg atggatcgta ttcatcagac ctatccttgt
    13381 gatgccattt tagctgaaga aaatgacgtt cgtcacccca ttaatcaagg aaatgtttgg
    13441 gtcatcgatc ccattgatgg aacggttaac tttattgtgc agggatcaca gtttgcagtg
    13501 atgattgcct attatgaaca aggaattggc caatttgggc ttatttatga tgtgatggca
    13561 gatcaattac tagctggtgg tggtgatttt gaagttactt taaacggtga taagcttcca
    13621 gcttaccaag aaaaaccttt agagcgtagc ttaattggct gcaatgcagg catgtttgcc
    13681 agaaatgatc gtaaccttgc tcatctaatt gcaaagactt taggtgtaag ggtttatggt
    13741 ggtgcaggta tctgcatggt taaggtcatg aagcaggaat tactggccta tttttcattt
    13801 atccaaccat gggattacgc agcagcaaaa gtactaggtg ataaactggg ttatgtttta
    13861 ctaactattg acggatatga acctgatttt caaacacgtc aaaaaatcat gtttgttcct
    13921 aaatgccaac tcactaggat agcgtctttt ctaacaaagg actctgccgt catacttgaa
    13981 gatcaataga aatgatgtca ttaccaaaag aatttattaa catttatcaa gcaatactag
    14041 gcaaagaatt agaagatttc ttggcaagtt ttaaccaaga gccggtcaat gcttttcgga
    14101 ttaacccctt aaagaatcaa ctaaaaacct ttgaacaccc cattccaaat accttatggg
    14161 gatattatgg taaactatct ggcaagtctc cagagcatgt gtcggggttg gtttattccc
    14221 aagaaccagc ggctcaaatg gtggcacaag tagcggctcc tcaaaaggag agtcgtgttt
    14281 tagacttggc agctgcacca ggaggaaaat caactcattt attagcttat ttagacaata
    14341 caggtctttt agtcagcaat gaaatttcta agaagcgcag caaggtttta gttgaaaata
    14401 tcgaacgttt tggcgctaga aatgttgtgg tgactaatga atccgcagat cgtttagcca
    14461 aggtattttc tcattatttt gatactatcg tctttgatgg accatgttct ggtgaaggaa
    14521 tgtttcgcaa ggaccctgat gctattcaat attggcatca cgggtatccc gcagaatgcg
    14581 ccaagttgca aaaatctatt ttagaagacg ccttaaccat gttaaaacca ggaggagaat
    14641 tgatatactc cacctgtact tgggctcctg aagaaaatga agatgttgtg cagtggctct
    14701 tagagactta taccttttta gaattggtcg atgttccaaa actaaatgga atggttagtg
    14761 gtatcggact tccagagact gctagaatgt accctcatcg ttatcaaggg gaagggcaat
    14821 ttgtggccaa gctaaaagat aagcgtcaag aaggacaaag cactaaacta aaagcaccta
    14881 aatccaactt gaccaaagac cagttacgtc tttggaaaat gtttgaaaaa gaccatctaa
    14941 accttaccct atcaggaaca ctacaaacct ttggtgatta cctatacctc ttgccagatg
    15001 gtcttcctgc tttagatggc cttaaaattg ctcggaacgg tttagaatta ggcgtcttca
    15061 agaagaaacg ctttgaaccc tcttacgcct tgggattagc tttaaagtct gatgaggtcc
    15121 gatcatctat tgagcttaga gaggaagact ttagacctta tgtgtcaggt aacgtcatta
    15181 ctttgcccca atcttatcca acaggctggt accaattact cattaatggc aatggtctag
    15241 gatttgccaa ggtcgttgac aagaccatca aaaataattt ccctaaaggg ttaagatttt
    15301 agcgtaaaaa ataagattaa aatgttaaat atttaaagaa aaaatgcttt c
//
LOCUS       DAUGOH010000038        13964 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUGOH010000038 DAUGOH010000000
VERSION     DAUGOH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13964
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.038"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..813)
                     /locus_tag="VH957_001360"
     CDS             complement(<1..813)
                     /locus_tag="VH957_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559265.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAETSTLTP
                     QGRQEKIKKIKDHITQYPKINEDRFWDRNWLRNSFKDEDYLKAVQNFTEQALQEILDL
                     IEKGATKGDKGDAGPRGERGPQGPEGKQGKAGERGAQGPKGDRGEQGIQGKPGEKGDK
                     GETGERGEKGETGATGAQGPQGEAGKDGAPGEKGEKGDRGETGAQGPVGPQGEKGETG
                     EQGPAGPQGEAGKPGEQGPAGPQGEAGKPGEKAPEKSPEVTPTPEMPEQPGEK"
     gene            1195..1677
                     /gene="nrdI"
                     /locus_tag="VH957_001361"
     CDS             1195..1677
                     /gene="nrdI"
                     /locus_tag="VH957_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8559266.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            complement(2071..2889)
                     /locus_tag="VH957_001362"
     CDS             complement(2071..2889)
                     /locus_tag="VH957_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEQ8559267.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPNIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMADETDYRTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLDWR"
     gene            complement(2972..5158)
                     /locus_tag="VH957_001363"
     CDS             complement(2972..5158)
                     /locus_tag="VH957_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8559268.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDHNTQATPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKVGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLT
                     SKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTTEIQDVTLTSLGNQPAKTKVATVEL"
     gene            complement(5515..6264)
                     /locus_tag="VH957_001364"
     CDS             complement(5515..6264)
                     /locus_tag="VH957_001364"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEQ8559269.1"
                     /translation="MQQYFIKGKAEKEVTITDKDTIKHMFQVMRLADEAEVILVFDDG
                     VKYLAKVTNSMAHELEIIETLPDQVELPVEVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEQKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKSGVKLLFIFGPEGGISPAEITQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            complement(6264..7217)
                     /locus_tag="VH957_001365"
     CDS             complement(6264..7217)
                     /locus_tag="VH957_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEQ8559270.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIEQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMIQGEWNALVFKKTDDISGVIGG"
     gene            complement(7288..7758)
                     /locus_tag="VH957_001366"
     CDS             complement(7288..7758)
                     /locus_tag="VH957_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEQ8559271.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEAASYPYPRY"
     gene            7959..9716
                     /gene="pabB"
                     /locus_tag="VH957_001367"
     CDS             7959..9716
                     /gene="pabB"
                     /locus_tag="VH957_001367"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEQ8559272.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIENVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDEFAVISASPELFFKQEGNQLTTRPMKGTTKRGVNTWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQIGSVCVDRLCEVERYSTVWQMTSTIVGDLKADCDL
                     IDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVQQKTVFLYRHKQIFDLKTTAKVEHQKIAFL
                     EQHLNRLKEAATYFAYPYDEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQVFYNQAGQLLETSIGN
                     LFIQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            9749..10315
                     /locus_tag="VH957_001368"
     CDS             9749..10315
                     /locus_tag="VH957_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEQ8559273.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVFSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            10348..11616
                     /locus_tag="VH957_001369"
     CDS             10348..11616
                     /locus_tag="VH957_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEQ8559274.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKKAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDSSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLKTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            11705..11901
                     /gene="ssrS"
                     /locus_tag="VH957_001370"
     ncRNA           11705..11901
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VH957_001370"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            11902..11974
                     /locus_tag="VH957_001371"
     tRNA            11902..11974
                     /locus_tag="VH957_001371"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11935..11937,aa:Lys,seq:ctt)
     gene            12115..12555
                     /locus_tag="VH957_001372"
     CDS             12115..12555
                     /locus_tag="VH957_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8559275.1"
                     /translation="MKIIEYKGNYRDNLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLTFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            12610..13116
                     /locus_tag="VH957_001373"
     CDS             12610..13116
                     /locus_tag="VH957_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEQ8559276.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVVHLDQLHFSSNWQERS
                     DHDMIADLSTCLLNQDWIIEGNYANCLYEERMSEANHIIYVNFSRFHCLYRAFKRYLN
                     YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVIQKYPHKTIVLTNQKQL
                     NHYMNTIN"
     gene            13365..>13964
                     /locus_tag="VH957_001374"
     CDS             13365..>13964
                     /locus_tag="VH957_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8559277.1"
                     /translation="MKKTKLIFSLTSIFIAIISRPVFGLEVDNNSLLRNIYSTIMYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDKIAVFSVPFDWNYL
                     SEGKVIAYTYGGITPYQKTSIPKNIPVNLWINGKQISVPYNEISTNKTTVTAQEIDLK
                     VRKFLIAQHQLYSSGSSYKSGKLVFHTNDNSDKYSLDLFY"
BASE COUNT         3958 a         3205 c         2722 g         4079 t
ORIGIN      
        1 tttttcacct ggttgctctg gcatttctgg cgttggtgtc acttctgggc tcttttctgg
       61 agctttttcg cctggtttgc ctgcttcacc ttgtgggcct gctgggcctt gctcacctgg
      121 tttgcctgcc tcaccttgtg ggcctgctgg gccttgttcg cccgtttcac ctttttcacc
      181 ttgtgggcct actggacctt gagctccggt ttcaccgcgg tcaccttttt cacccttttc
      241 gcctggagcg ccatctttac cagcttcacc ctgtgggcct tgggcgccag ttgctccggt
      301 ttcacctttt tcaccgcgct caccggtttc acctttgtcg cctttttcac caggtttacc
      361 ttggattcct tgctcaccgc ggtcaccttt aggaccttgg gcgcccctct caccagcttt
      421 accttgcttg ccttctggac cttgtgggcc gcgctcgcct ctcggaccag catcaccttt
      481 atcgcccttt gttgcacctt tttcaatcag atctagaatt tcttggagtg cttgttcagt
      541 aaaattttgt actgctttta aataatcttc atccttaaaa gagttacgga gccagttccg
      601 atcccaaaat ctgtcctcat ttatttttgg atattgcgta atatggtctt taattttttt
      661 aattttttct tgtctgcctt gtggcgtcag agtagaagtc tcagccttaa cgctgcttgc
      721 cccgcctcca aaggctagaa ggacggcagc ggctgaggtt agcccgtagc gccagaccag
      781 tttgttgaga ttatggtgtt ttgatgtcaa catatgttgt tctctctttc tctattagat
      841 gatgtgtttt agataaaaat aacatggtag ctagacctga ttatttataa cagtattata
      901 atagagtgtg aaaacgattg taaagttctc ttttgttgtt catcttttag attttgactg
      961 attgctcttt tgtggagatt agagggccac tttggcactt gcctgcctcg tttttaagtc
     1021 gagggcaagc ggatcctttg tttaaggtca ctctttttta aaatgttact ttttttgact
     1081 gcttgtacct tcttgtctgg ttggataccg ctaggtttct tctttacttg tttgttggtc
     1141 ttgattgtgg taagcttatg aagaaacctt gtaggataaa aaaaggagac acttatgcct
     1201 cagattaccc ttgtttttat tagcctcagt ggcaacaccc ttagctttgt caagcggcta
     1261 tccctttatc tagcagacaa ttacgattac catgtcaaac agattaacat taaagatttg
     1321 aaacacgaga cttttcccgt caaggaagag tttgtggcga ttctacccac ttatctagaa
     1381 ggcggaaatg gcgttgactc tggtgaggtg gagatcctca ccactccttt gggagagttt
     1441 attgctgccc atggcaacgc ccagcgttgt cttgggatta ttggctcagg caacaaaaac
     1501 tttaaccatc agtattgcct gacagccaaa cagtatgcca aacgctttgg ctttccactg
     1561 ctaggtgatt ttgagctgcg agggactcct gatgacattt cgcggttagc ccaggtcatc
     1621 atggaggcca gctccagaca ctcgtctaac gacacacaga cactgcctaa cagctagaca
     1681 gtctatagat gatcatagct gttttaaaaa agagcacttt taggacacca actagggaag
     1741 gcccctaccc cacgccttgt gatttctcag ccttttaaaa gagcgatcac agtgcttctt
     1801 ggggcttggg atcacaccaa gcactcctag aaatatcccc atgcagactt tagcaaggca
     1861 actgtacgct tggtggtact ttctgtgaag ctcagatggt tgggggcaaa aaagccctgg
     1921 ttttttaggg ttactgacat gactaaagag gtctaaccag ctcaaggtag agctggttag
     1981 acctctttgt gttctcctaa tccccctaga cgatcgcagt ttcttatgtg tcttggcttc
     2041 tcctatgtgg tgtgcctgtt agcacatgct ctaacgccag tctaatgtca cttctaaacc
     2101 atagtggtca ctgacgactg gcgcatcccc gccttcaaag gtaatcttag aagatcggat
     2161 gatgaagtcc ttactggtaa agacatgatc caccttgagg gcttctttgt taccttgcca
     2221 gccatcaata tcagccacga tgctatgatc accaaacacg tggtcagcaa ccttatggct
     2281 atcttgtagg tctagggggc tacccatcat cacttgataa ccgtcttgat ccgttggatt
     2341 gttaaaatct cccataagta gcaagggaca gtttagcgtg agcagctctt tttctaattt
     2401 ctcccactcc cctaaaaacc ccttgtcaaa ccatgacaag tgcacattga caacagcgac
     2461 ttctttgcca tctaacgtgg ttttggctat gagtgagcgt ctggtacggt agtctgtttc
     2521 atcagccatc gctgacacga gaatatctga aacatgaata ggttgttttg ataagattgc
     2581 cacgccttcc tggtaaatgt catagccaat atggttataa gcccaagacc aataatagtg
     2641 ctgccctcgt ttttgtaaat aatggatcaa gagaagagca aaatggtctt tatgaatgtt
     2701 tggtgtccct gaaagagctt gatatcttgg taaatctgtg gccagctcgc tctcgattaa
     2761 ctgattgatt tcttgcaagc aaatgatatc gtatttttca gctaaaatat gctcagccaa
     2821 agcaactaat tttttaagag tgttagcttg catccacgaa tgggtattca gtgttaatac
     2881 cttggtcatt aatcctcctt tataagacaa gaagagccat agggcctaaa ccagctatgg
     2941 ctattaccta tcactatctc gtgatgtttt gttaaagctc tacggtggct actttagtct
     3001 tagcaggttg attgcctaaa gaagtcaagg tcacatcttg gatctctgtt gtgttggtaa
     3061 aggctaccac gatagtggtc tcacgctctg ctgatttaat agcagcaaga tctgctacga
     3121 ctaataggtc acctgcatga acccgttgcc cttctgagac tttgactgaa aaaggcacac
     3181 catttaaggc gacggtatca agtcccacgt gcaccagcac ttcaagacca ttatctgtca
     3241 gtaaaccaaa ggcatgcttg gtcggaaaga cactggtcac aaggccagct acgggtgcat
     3301 agatattacc atgggttggt tcaaccgcaa acccatctcc catcatctta gccgcaaaca
     3361 cctggtcttt cacacctgtg attgggagaa ccatcccgtc tgccactgat agcacatctt
     3421 ctgtcacgtg tttaaaatct tttgcgggag tcggtttgct agtgagctgt gacatgttga
     3481 cttctggaat aagagcccct gagtccagca aatcttgaat atctgatttc aaaatatctg
     3541 ctttagggcc atagaccgct tgaacgccgt tgcctttttg gatcaagccc atagcgccag
     3601 cttttttcca atcgtcctca gcgccaacct tagcggggtc tttgaccgtc actcgtaagc
     3661 gcgtcataca agcatcaaca tcatcaatat tgcctgcccc accaaggaga ttgatgattt
     3721 gtacgacttg agagttgcta tctgctactt gggtcggtgt tgcttgagtg ttatggtcac
     3781 ccagtatatc ggcatcgtag ttgcctaaac gaccagctgt tgcgagatgc attttcttga
     3841 tcatcatatc tgcaataaag tacatgataa ctgcaaagag gatagaaacc caaacaaagt
     3901 taatcacatc catgcctagg cctgctttaa gggccatagg ggtacgggtc aataattcaa
     3961 tgttcccaaa tgagtgaaca cggagattca caaggtcagc catggcaaat gaagctcctt
     4021 gaacaagggc atagacgatg taaagtggca ttgctgcaaa cataaatagg tactcaagtg
     4081 gctcagttac ccctgtcaaa aagaccgctg ccgctgctga gatgaacatc attttgtatg
     4141 tgtgtttttt atcggcatcc acattacggt acatggctaa ggcaaccccc atcaatgttc
     4201 cggtagctcc aatcatttgt cctaccttaa agcgagctgg agtcacacta tccattaagt
     4261 gactataggc tgaagcgtct gatcctttaa ggtgaacaag gtcagttacc caagcaagcc
     4321 acaaagggtc ttgaccaaat acttttgtcc ccgctgctgc acctgtcatg acctcataag
     4381 ttccaccaag agctgtatag ttcattggga tcgtcaacat gtggtgaaga ccaaatggca
     4441 acaagagacg ttccaaggta ccatatagga atggggctag gattggagct gaatcttgtg
     4501 aagaggcaat ccacatccca aaactgttaa tcccagactg gatcaccggc caaacaacaa
     4561 ccaaaataag ggctacaaaa atagaacgta aaataacgac aaacggtaca aaacgcttcc
     4621 cattaaagaa ggtcaaaact tcaggaagtt tacggtaatt atagtatttg ttataggccg
     4681 ttgctcctac gaaccctgca ataatcccaa caaaaacccc tgtgtttaaa gctggagact
     4741 ccaagacact ggtgaaataa tctttaacga tcatttgagt gccaaggagg cttgtgattt
     4801 ttgcttctgg atcagctagc atagcactag acacgccata aaaagcgcct gttatccgat
     4861 tgatcaagac aaaagcaagc cctgaggcaa aggcccctcc agctctttct ttagcccaac
     4921 taccaccaat ggccaaggca aatagcaaat gaaggttaac aataacagcc cagccaatct
     4981 gagcgataat gttgcctaga gatgccaaaa atgctgagtc atggttaatc attggaatag
     5041 agtttccgat actgatcatt aaaccagccg ctggcatgac agcaataacg accataagac
     5101 atttcccaaa tttttgccaa aattcgaaac gaaacagttg cttgaatgat gttttcattc
     5161 tatctctcct ttattatccc cttttagcca tagctgccct taaggcgctt ttgtgacaca
     5221 atgatataga ctacaactca gtgatgcaat cgtttgcatt ggtctgatac ctttattata
     5281 ctagcctcgc aacaatttgt aaagcgtttt cttagacaga tgttagtcgt ttttcttcat
     5341 taaatggtag tgtaacttat caaaaagatg acaagagccc atttcctttt ttggtgatga
     5401 gcccatcaac gctcttcaaa aaaacaagaa gcaataaaaa aaggccgttg acacaatcgt
     5461 gaactgcctg ttcgtttctt tagcctcttc tttctaaagt aagcaacagc ttacttattt
     5521 tgatgcctgc aattccaaag cataactaag agcacttaag gcatataacg gcgctgtctc
     5581 tgctcgcata atgcgagggc ctaagcccac cttgatggca cctgctgcct caaactgagt
     5641 gatttcagct ggggaaattc ccccttctgg tccaaagata aagaggagtt ttacccctga
     5701 tttaacttcc tttacttcac gcgccaaggt cgctagctga cctgccttag ctgtttcctc
     5761 ataagcaatg aagatatgat caaagctaga aaggcttttt agaaactctg ctttctgttc
     5821 aaaaaggtga acttcaggca ccctatttcg tttgctctgc tcagccgctc ctaatacaat
     5881 cttagccaat ttgtcttctt ttttagctaa ttttttgcca tcccatttga ccactgacca
     5941 gtctgctggg tagccccata gcgcactggc tcccaattca gtcactttct gggcaatcgt
     6001 gtctaactta tctcctttag gaaatccaga agcaatggtc acctcaacag gcaattccac
     6061 ctgatctggc aaggtctcta taatctctaa ctcatgagcc atactattgg tcaccttggc
     6121 taaatacttc accccatcat caaagaccaa gataacttca gcctcatcag ccaagcgcat
     6181 cacttgaaac atgtgcttga tggtatcttt atcggtaatt gttacctctt tttctgcttt
     6241 gcctttaata aaatactgtt gcattagcca ccgatcactc ctgagatatc atctgttttt
     6301 ttaaagacaa gggcgttcca ctcgccttga atcatgtgtg tctcaaggaa gaatcctgcg
     6361 ctaaaggcag cttccagaac catatccaat ttctcagaaa tgatgcctga taggataagg
     6421 taaccttcct ttttgaccaa acggtaagca tcatcagtca ataagactaa gatatctgcc
     6481 aaaatattag ccacaatcac atccgcttct tggctaaccc cttttaaaag gtcgccagca
     6541 gccacatgaa tgttgtctgt tccttgattc aaatcaatgt tttcttgagc cactcgaaca
     6601 gccacgtcat ctaagtcata agcgtagatg gttttagcac ctagtaagga actggcaatc
     6661 gagaggacac ctgatccggt ccctacatcg ataactgtct caccaccacg aaggatttgt
     6721 tccaaggcaa aaaggctcat tttagttgtg ggatgtgtcc ctgtcccaaa tgccattcca
     6781 ggatctaatt taatcacttt ttccccagca gaagcgtcat aatccgtcca actagggaca
     6841 atggttaaat catgcgtgat gcgagctggt tcatagtatt ttttccaatt gtctgcccag
     6901 tcttcctcag ctaattcttg actgtccaca gtaacctgac caacctgtaa cccaaaacta
     6961 gctaactccg ctaactgttc attaatggtc gcaataacat ccgccaaatt agtgctactt
     7021 gggtaatagg ctgtgatagc tatcatatca gactgctcca catctgggta taactcccca
     7081 aagcggtcct tttgctcaat atagtctgcg ctatctgcga tagcaacccc ttggctgcct
     7141 gtctcaatca acacatgtga aacagcctct tgcgcatcac gatgcacatg aaccgtcact
     7201 tcttgccacg tttccataag tatgtccttt ctattttgac cttttggtta ttgtcctaat
     7261 agtgttagca ccatctcgtg tgtcacctta gtaccttggg taagggtaac ttgctgcttc
     7321 ttctagtcct tgttgacctt cttcaaaagc ttgcgcgttc cactccaaga agaaatcagc
     7381 cttgctgtca tctgctaaga aatccatcaa atcgctgtgc ccttcaatag caacatcgtt
     7441 gagaaattgc gcaaagtaag ctaagaattc acgagaaaag ccctttttgg cgtcaaaagg
     7501 aatagtaacc aaataatctg ctgcatcaaa ttgagacttg gcagggttgt aaaagagcac
     7561 atagtcctca aagacaatat catcttgggt cacttcgcca ctatcatcaa tggtttttat
     7621 ggcctcttta ttttgagctt ctaaaacaaa agtcacttcc accgcgtgat ttttcttgtc
     7681 ccaatccata gcatagtcat actgaaaatg cttatccatt tcttcttcta atactgataa
     7741 aaagccgtat tttgccatct ttttttatac ctaatctttc taactgttgc tgtatagagc
     7801 tttgtaagac ctcattagtt tacttacttt gacatgctga gcgtactgtt ataactttta
     7861 ttaactgaat tataacatat ttgactaata ttgaccataa gagaaggtct taatggcagg
     7921 atcacctcta gcaaccgcct ttatgatata atttgggtat gcatagaaaa acgattattg
     7981 acttcaaaga gctcgggcaa cgctatcttt ttgatgagcc attagtagaa ttggtagcca
     8041 agtccttaga tcaggtcggt ccagtcattg aaaacgtaca acactaccaa cagctgggct
     8101 attacgtggt gggctatctc agttatgaag cagctgcttt ttttgacaat gccctacaaa
     8161 cccataatga cagactaggc aacgagtacc ttgcctattt tacagtgcac aaaacctgtc
     8221 aaaaaaaaga cctacctctt gattatgaca gcattactat ccctaaccaa tgggtcagcg
     8281 caactcaaaa agaagcctat caaaaagcca ttgaaaccat tcaccgtgag atgcaacagg
     8341 gcaatacgta tcaggttaac tacacccttc aattaactca ggaactcaat gcagctgaca
     8401 gcttagccat ttacaataaa ctcgtcgttg aacaggctgc tggctacaat gcctacatcg
     8461 cccatgatga gtttgccgtt atttcagcta gtcctgaatt gttctttaaa caggaaggga
     8521 atcaactcac caccagacct atgaaaggca ccaccaaacg aggggttaac acctggctgg
     8581 atcaacaaga acatgactgg ctccaagctg acgggaaaaa tcgctctgaa aacatgatga
     8641 ttgtggattt gctccgcaat gacatgggga aaatttgcca aataggcagt gtttgtgttg
     8701 ataggctctg tgaggtcgag cgatactcta ccgtctggca aatgacctca accattgttg
     8761 gtgacctcaa agcggactgt gacctgatag acattctcaa agctctcttt ccttgtggct
     8821 ctatcacagg ggctcctaaa gtctccacca tggcaattat cacatctctg gagccaaaac
     8881 caagggggat ttattgtgga agtattggca tttgcctacc tgacggtcgc cgtttcttca
     8941 atgttcccat tagaaccatc cagctcagtc ataatcaagc tacttatggt gtcggaggcg
     9001 gtatcacttg gcaaagcaag tgggaagacg aatacgaaga agtccagcaa aaaacagttt
     9061 ttctctatcg gcacaaacaa atctttgacc tcaaaacaac cgccaaggtg gaacaccaaa
     9121 aaatagcctt ccttgagcaa cacctcaatc gccttaaaga agcagccact tattttgctt
     9181 acccttacga tgagaaagct ttgcagaaac aactgtcaac ctatttggaa aataaggata
     9241 atgctgccta ccgtttgatg attcgtttat ccaaagatgg aaagattagc ctctctgatc
     9301 aacccttgga acctttgtca gccgattttc tgacagctca actctcttta cagaagaagg
     9361 acgtgacagc ttcgcctttt acctacttta aaaccagcta ccggcctcat attgagcaaa
     9421 aatcttatga acaggtgttc tataaccaag cggggcaatt attggaaact tccatcggca
     9481 atctttttat ccagctgggt cagaccctct acacaccacc agtggctgtg gggattttac
     9541 caggactttt tcgccaagag ctgctagcta ctggtcaagc tcaggaaaaa gaggtgacac
     9601 tagctgattt aaaagaagct agcgctattt ttggaggaaa tgctgtccgt ggcctctatc
     9661 ctctcaacct tgagcttact caccttgatg ccctcttagc taagagtcaa gcctaaactg
     9721 ccactcatct tttgttatta aggaacctat gatactctta attgataatt acgattcatt
     9781 tacctacaac ctcgcccaat atttaagtga atttgacgag acgattgtct tgtataacca
     9841 agacccaaac ttatatgaca tggccaaaaa agctaacgct ctagtctttt cacctggtcc
     9901 tggttggccc aaggaagcca accaaatgcc aaaactcatt caagactttt accaaacaaa
     9961 acctatctta ggagtgtgtc tgggacacca agctatcgct gaaactctag gaggaacctt
    10021 acgcttggca aaacgcgtca tgcatgggag acaaagcacc attgaaacgc aaggccctgc
    10081 tagtcttttt cgctccctgc cacaagagat caccgtcatg cgttaccatt ctatcgttgt
    10141 ggatcagtta ccaaaaggtt ttagcgtaac tgctagagac tgtgacgatc aagaaatcat
    10201 ggcctttgaa caccacaccc tgccactttt tgggctacaa tttcacccag aaagcatcgg
    10261 aactcctgat ggcatgacca tgatcgccaa cttcatcgca gccattcccc gttaatctca
    10321 tcccccaaaa gaaaggagga cagttacatg cctgatcact tagcgctcag aatgcgcccc
    10381 aaaaccattt cagaggtcat cggacaaaaa caccttgttg gcgaaggcaa aatcatccgt
    10441 cgcatggtgg aagcaaatag actatcgtcc atgatcctct atggccctcc aggaatcggt
    10501 aaaacttcca ttgcttctgc tattgctggt actactagat atgcctttcg tacttttaat
    10561 gccactgttg atagtaaaaa acgtctccaa gaaattgcgg aagaagctaa attttctggt
    10621 ggcttggtat tattactaga cgagattcat cgccttgaca agacaaaaca agattttctt
    10681 ttacctttac ttgagaatgg caccattatc atgattggcg caaccactga gaaccccttc
    10741 ttttcagtga cacccgctat cagaagcagg gtccagattt ttgaattgga accactttct
    10801 aacgaggata ttaaaaaagc cattcagcta gcaatttccg acaaagaacg gggatttcct
    10861 tttttagtga caattgatga tgaggcgcta gatttcattg ttaccgccac aaatggagac
    10921 ctacgatctg cttataattc cttggatcta gcagtcatgt ctacttctcc taatgaagat
    10981 agtagccgtc atattagtct agagacaatg gaaaatagtc tgcagcgtag ttatattacc
    11041 atggataaaa acggggacgg gcattatgat gttttatctg ccttacaaaa atccattaga
    11101 ggttctgatg tcaatgctag cctgcactac gccgctcgtt tagtagaagc tggagacttg
    11161 cctagtttag caagacgatt gaccattatt gcttacgaag atattggctt agccaaccct
    11221 gacgcccaag ttcataccgt caccgcacta gatgccgccc aacgcattgg ttttccagaa
    11281 gctcgtattc ttatcgctaa cgtggtcatt gatttggctc tatctcctaa atcaaattca
    11341 gcttatttag ctatggatgc agctttagct gatttgaaaa catcaggtaa cctccctatt
    11401 ccaaggcatc ttagagacgg gcattatgct ggcagcaagg acctaggcaa tgccaaagat
    11461 tacctctacc cacacgccta ccctgaaaaa tgggtcaaac aacaatacct accagataaa
    11521 ttagtaggac atcattattt tgaagccaat gaaaccggta aatacgaacg cgcacttggt
    11581 tcaaataaag agcgtattga taagctctca gactgactgc tagttttaaa aatcgcaacc
    11641 gatttcaaaa atcgataatt ttgcttgaaa aaattttaaa aagtggtatt ataaaagtac
    11701 agaaacattg ctgtggcata cgaatccaca tctaagtgtt gaccgactat ttctttgtat
    11761 tttcgggaaa caaagactct ttctagtctg caagccgttt cacgcggacg caacttccaa
    11821 gaaagagcgc gttacccacc tgcttatact gcgcgggctc aatacaaaaa cgtggatcac
    11881 cggtgccaat acagcattct tgcctcctta gctcagttgg tagagcagta gactcttaat
    11941 ctatgggtca caggttcgag ccctgtaggg ggtatacaac tatacatgaa aaaacctttg
    12001 tttaaaggct ttttttgctt gtcagaagag gatttgttcc atcatttatc cccgcagtaa
    12061 tttttttatg gtatgatacc aattaaagcg cttaagatta aggtggagac tgttatgaaa
    12121 ataattgagt acaaaggaaa ttacagagat aacctcattt ttatggtctt ggaagcaaaa
    12181 aatgccttaa ggagaattcc cagcattaac ccggatcttt tgacaattga aacaagttat
    12241 ttggaaaaag gggattgttt ttggctagcg gtcaatgaag aaagtcgtgt tattggctca
    12301 atcgcttatt cttctattcc caaaacaaat gaggtcttct tgcaccgtct cttcatcaaa
    12361 ccaagcttaa aacatcaagg cattggcagt caacttctga cgtttgcaga agattatcta
    12421 aggaaaatcg gcaagagtca tgtccgtatc cacttaggtc aacctaaaga acaatggttt
    12481 gagtcttatc ggttttatcc taaacatggt tatcaatttt atgatgacac gcatctcatc
    12541 aagaaactaa tctaaacaca tttcctaccc tttatagtca tttcatacgt catttttagg
    12601 aggtatccat tgaaaattgc catcattgga catagtggct ctggcaagtc aaccttagca
    12661 cgatttttag gtcaacatta ccattgtgag gtggtccatt tagaccaact acacttctca
    12721 tcgaactggc aagaacggtc agatcatgac atgatagctg atttatcaac atgcctgctc
    12781 aatcaagatt ggattattga ggggaattat gccaattgtc tctatgaaga gcgcatgagt
    12841 gaggctaatc acattatcta tgttaatttc agtcggtttc attgtctcta tcgagcgttt
    12901 aagcgttatt taaactatag gggaaaaaca cgtcctgata tggctgacaa ctgtcaggaa
    12961 aaatttgacg ttgcgtttgt gaaatggatt ctactagatg gacgttcaag aaaccaatta
    13021 aaaaaatacc aatccgttat ccaaaaatac cctcataaaa ccattgtctt aacaaatcaa
    13081 aagcagctca atcactatat gaatacaatc aactaattag agtgaaaaac taaaatagcc
    13141 acgggtaacc cgggctattc agactgaaag cctttgttta aaggcttttt tgcttgtttc
    13201 ataactaatc ggcttaatta aaagcgtcaa tccactttta gtatcatgtc tcaattttca
    13261 tttgatagtc agcaagtata tctacaaaat tgttaatgat tatttctttt gaaagtgtta
    13321 tattaaaaca taataaaata ataactcctg aaaagaggct atttatgaaa aaaacaaaac
    13381 ttattttttc tttgacttca atattcattg caataatttc tcgtcctgtg tttggattag
    13441 aagtagataa taattccctt ctaaggaata tctatagtac gattatgtat gaatattcag
    13501 atacagtaat tgattttaaa accagtcata acttagtgac taagaaactt gatgttagag
    13561 atgctagaga tttttttatt aactccgaaa tggacgaata tgcagccaat gattttaaag
    13621 ctggagataa aatagctgtg ttctccgtcc catttgattg gaactacttg tcagaaggaa
    13681 aagtcatagc atatacgtac ggcggaataa caccctacca aaaaacttca atacctaaaa
    13741 atatccctgt taatttatgg attaatggaa agcagatctc tgttccttac aacgaaatat
    13801 caactaacaa aacaacagtt acagctcaag aaattgatct aaaggttaga aaatttttaa
    13861 tagcacaaca tcaattatat tcttctggtt ctagctacaa aagtggtaaa ttagtttttc
    13921 atacaaatga taattcagat aaatattctc tcgatctttt ctat
//
LOCUS       DAUGOH010000039        13786 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUGOH010000039 DAUGOH010000000
VERSION     DAUGOH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13786
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.039"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            45..1499
                     /locus_tag="VH957_001375"
     CDS             45..1499
                     /locus_tag="VH957_001375"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEQ8559278.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEDLGFIILGRSNTPEFGFKNISDSSLHEPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALAPASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLNDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            1617..2480
                     /locus_tag="VH957_001376"
     CDS             1617..2480
                     /locus_tag="VH957_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8559279.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWETIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            2509..3159
                     /locus_tag="VH957_001377"
     CDS             2509..3159
                     /locus_tag="VH957_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8559280.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
     gene            3292..3945
                     /locus_tag="VH957_001378"
     CDS             3292..3945
                     /locus_tag="VH957_001378"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEQ8559281.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPSRENVFK
                     ALQVTPLEKTKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWELFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            4077..5345
                     /locus_tag="VH957_001379"
     CDS             4077..5345
                     /locus_tag="VH957_001379"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEQ8559282.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVEVVAFAQRLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(5403..6044)
                     /gene="plsY"
                     /locus_tag="VH957_001380"
     CDS             complement(5403..6044)
                     /gene="plsY"
                     /locus_tag="VH957_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEQ8559283.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            6179..8128
                     /gene="parE"
                     /locus_tag="VH957_001381"
     CDS             6179..8128
                     /gene="parE"
                     /locus_tag="VH957_001381"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEQ8559284.1"
                     /translation="MTKNEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVDSIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGANFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVETGHVYIALPPLYKMSKGKGKTEKIAYAWTDGEL
                     EDLRREFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTINDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            8219..10678
                     /gene="parC"
                     /locus_tag="VH957_001382"
     CDS             8219..10678
                     /gene="parC"
                     /locus_tag="VH957_001382"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEQ8559285.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAGKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            10756..11823
                     /locus_tag="VH957_001383"
     CDS             10756..11823
                     /locus_tag="VH957_001383"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEQ8559286.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            11887..12117
                     /locus_tag="VH957_001384"
     CDS             11887..12117
                     /locus_tag="VH957_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEQ8559287.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            12178..12258
                     /locus_tag="VH957_001385"
     tRNA            12178..12258
                     /locus_tag="VH957_001385"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12212..12214,aa:Tyr,seq:gta)
     gene            12309..12380
                     /locus_tag="VH957_001386"
     tRNA            12309..12380
                     /locus_tag="VH957_001386"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12341..12343,aa:Gln,seq:ttg)
     gene            12507..13712
                     /gene="rpsA"
                     /locus_tag="VH957_001387"
     CDS             12507..13712
                     /gene="rpsA"
                     /locus_tag="VH957_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEQ8559288.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
BASE COUNT         4379 a         2491 c         2942 g         3974 t
ORIGIN      
        1 aaaagaatgt tttaggattc atatcttaga aaggaagagt agctatgact tatcaagatg
       61 cgacggctat ggctattgct gttcagaccg gtcagaccac accactagaa ttagtaaccc
      121 aggctattta taaggctaaa aagttgaacc ctaccttaaa tgctattacc tcagaacgct
      181 ttgaagcagc cctagaagaa gccaaacaaa gggatttttc aggtaagcct tttgcaggag
      241 ttcccatttt tttgaaagat ttgggacaag aattaaaagg tcactcatca acctcaggtt
      301 ccagattgtt taaagagtat caagcgacta aaacggattt attcgtgaaa aggttagaag
      361 acttgggatt tattatttta gggcgttcta acacacctga atttggcttt aaaaatatta
      421 gcgatagcag tttgcacgaa ccagtgaatt taccaaagga taatacacga aatgctggtg
      481 gctcatctgg gggagctgct gctctagtgt catctggaat tagtgcacta gcaccagcta
      541 gtgatggggg tggctctatt cggattccag cctcgtttaa tggcttaatt gggctcaaac
      601 ctagccgcgg gcgcatgcct gtcggacctg gttcttatcg aagctggcaa ggagcctcag
      661 ttcattttgc cttgaccaaa tccgttagag atactagaaa tctactctac tatttacaga
      721 tggaacaaat ggaaagcccc ttccccctag ccaccttaac aaaagatagt atttatcaat
      781 cgctacaacg tcccttgaca attgcttttt atcaacggtt aaatgacggt agcccagtat
      841 ctttagatac tgcaaaagct ttaagacaag cagtaacttg gctaagagaa caagggcatc
      901 agctagttga attggaagag tttcctgtaa atatgacaga agtgattcgt cattattata
      961 ttatgaatag tgtggaaacg gctgctatgt ttgctgatat tgaagacact tttggacgtc
     1021 cgatgaccaa agacgatatg gaaaccatga cctgggctat ttaccaatca ggtaaagaca
     1081 tcccagcttg gcgttactca caggtccttc aaaaatggga tacgtacagt gcaaccatgg
     1141 ctagttttca tgagacttat gacctgttgt tgacgttcac aaccaacaca ccagctccta
     1201 agcacggaga acttgtccca gattcgaaac tcatggctaa cttggctcaa gctgaaattt
     1261 tcagcagtga agaacaattc aatttggtcg aaaccatgtt tggtaagagt ctggctatta
     1321 atccttacac agctctgcct aatctaactg gccagccagc tattagttta cctacttacg
     1381 aaactaagga agggctccca atgggcattc aactaattgc agccaaaggt agagaggacc
     1441 tattattagg aattgcagag cagtttgagg cagcaggatt attgaagatt cctcaataat
     1501 aatcttataa aacagtttaa ctattataga ttaacttttt aaagagattg agcgctcact
     1561 gataacacaa cttaatcaaa atgttatact attcttatct taataaagga gttactatga
     1621 agaaatcagt tactttactg tctatcggac ttgccagcct tttattggca gcatgtgcgc
     1681 cacataaatc tcaaaaatca agttgggaga ctatcaaaga aaaaggggtg ttaaaagtag
     1741 ctaccccagg aacctatcag ccaacttctt tttacaacga taataatgag ttagtaggtt
     1801 acgaagtaga tatggtcaag gaaatcggta aacgacttaa cattaaagtc aagtttgttg
     1861 aaacaggatt tgaccaagcc tttacctcag ttgatagtgg tcgagtggat atttctttga
     1921 acaactttga cattacccca aaacgtcaga aaaaatacaa tatctctacg ccttataaat
     1981 acggggtagg aggcatgatt gtccgtgctg atggcagctc aaacatggct aaaaaagatc
     2041 ttagcgactg gaaaggaaaa aaagcagccg gcgcttctgg aacagagtac atgaaagtag
     2101 cacaaaaaca gggagctgaa ctggtgacct acgataatgt tacaggagat gtttatctaa
     2161 acgatgtggc taacggtcga acagatttca ttccaaatga ttacccagct caaaaattat
     2221 ttgtggatta catgttatct caaaatccaa atctaaatgt caaaatgagc gatgttcagt
     2281 acaacccaac cgaacaagga attgttatga acaaaaaaga cgatagcctc aagaaaaaaa
     2341 tagatgctgt tattaaagac atgataaaag atggtagctt gaagaaaata tctgaaacct
     2401 actatgctgg tcaagatttg acaaaacctt ttggcaaaga caaaaaaatt cccgtcattg
     2461 atacgaaaga cgttaactaa tacttgatgt taaaggagtc ctaaccacat gattaatatc
     2521 ccattaatga aagatagttt aggatttgtg ttatcgggat taccttatac ccttggtatt
     2581 tcgttgctca gtttttttac gggtctgttt ttaggtttag gcctagccct tctgggaagg
     2641 tcacgtcagc cgttgattca ttatcttgtt agagcgtaca tctctattat gcgaggtgtg
     2701 ccgatgatcg tggtgctctt tgttctttat ttcgggttgc cttattatgg tttagaattg
     2761 ccagctttac tttgcgctta tcttggtttt tctatggtca gcgctgccta catttctgaa
     2821 gtttttcgct cttctataga agctattgat aagggacaat gggaagcagc taaggcttta
     2881 gggttgccat atgctcttat ggttaagaaa attattcttc ctcaagcctt tcgaattgca
     2941 gttcctcctc taggcaatgt cattattgat atggttaaaa gttcgtcgct agctgccatg
     3001 attaccgtac cagatatttt tcaaaatgcc aaaattatcg gtggtaggga gtgggactac
     3061 atgtccatgt acattttagt agcctttatc tattggatta ttgctttttt gttagaacgt
     3121 taccaagaat tcttagaaaa taagctagca cttgtttaat atcctgtaaa aaacgaatat
     3181 taaccctgga aatatcatat tttcagggtc tttctattta aaatgtggta aactagatag
     3241 aaaaggacat cgtatttaac ttagaaactg acgtgattag aaaggaatct tatggctcat
     3301 tcaatttggc atgagaaaat caaatcattt ttgccggagc attactacgg tcgcatcaat
     3361 cactttttag atgaagccta tgcttccggt cttgtctatc cttcacgaga aaatgtcttt
     3421 aaagccttac aagtcactcc tttggaaaaa accaaagtgt tgattttagg acaagaccct
     3481 tatcatggcc ccaaacaggc ccagggctta tcattttcag ttccagaaga gatttctgct
     3541 ccgccatccc ttattaatat tttaaaagaa ttagcagatg acattggtcc tcgtgaccat
     3601 catgatttaa gcacttgggc tagtcaaggg gttctgcttt tgaatgcttg cttaacagtg
     3661 ccagcaggcc aggctaatgg gcatgcaggc ttaatatggg agctatttac agacgctgtt
     3721 attaaagtgc tgaatgagaa agacagccct gtagttttca ttttgtgggg agcttatgca
     3781 aggaagaaaa aagccttcat tactaatcca aagcaccaca tcatcgagag ccctcatcca
     3841 agccctttgt catcttatcg tggctttttt ggcagcaaac ccttttcaag aaccaacgct
     3901 attttagaaa aagagggcat gactggcgta gattggctaa aataagccag ccatttcaac
     3961 taaatagctt aagctagaca ttttgatacc tttaataagt gaaatgagcg cagtagattt
     4021 ttcctattaa agaacgtaag gtcttatggt taaaacagat aaataaagga gaaaacatga
     4081 tactcatcaa aaatggacgc gttatggacc cgaaatcgca gagagatcaa gtggcagatg
     4141 tcttgattga tggtaaacag attgtaaaga tagcttcagc tattgaatgc caagaagctc
     4201 aagtgattga tgctagtggt cttattgttg ctccgggttt ggtcgatatt catgtgcatt
     4261 ttagagaacc cggtcaaacg cacaaagaag atattcacac gggagccttg gcagcagcag
     4321 caggtggtgt gactacggtt gtcatgatgg ctaataccaa tcctgtcatt tcagatgtcg
     4381 aaactttaca ggaagtgtta gctagcgcag ctaaagaaaa gattcatatt tacaccaatg
     4441 ccagtgtcac ccaagccttt aatggaaaag acgtgactga ttttaaagct ttgttggaag
     4501 caggagcagt aagcttttca gatgatggta ttcccttaga aagttctaaa gttttaaaag
     4561 aagcctttga tttggctaat gccaaccaaa ctttcatttc tttgcatgag gaagatcctc
     4621 agttaaatgg ggttcttggt tttaatgaag gtattgctga ggagcatttt catttttgtg
     4681 gggcaactgg tgtagcagaa tatagtatga ttgcaagaga tgtcatgatt gcttatgaca
     4741 ggcaagctca tgttcatatc caacatttat ctaaagcaga atcggttgaa gtagtggctt
     4801 ttgctcagcg gttgggtgct aaggtaactg ctgaagtgtc cccacaacat ttttcaacaa
     4861 ctgaagatct cttattgacc gcaggtacca gcgccaagat gaatcctccc cttcgtacac
     4921 aaagagatcg cttagctgtc atagaaggct tgaaatcggg tgttatcaca gtcattgcca
     4981 ctgatcatgc tcctcatcac aaggatgaaa aagctgttga tgatatgact aaagccccat
     5041 ctggtatgac aggacttgaa acttctttgt cattaggttt gacgcatttg gttgaaccag
     5101 gtcatcttac acttatgtca ctattagaaa aaatgacgct taatccagct ttgctttatg
     5161 gttttgatgc gggttatttg gcagaaaatg gtccagcaga tttggttatt tttgcagaca
     5221 agcaagaacg tctgatcact gagaattttg cttctaaagc tagtaattcc ccatttattg
     5281 gtaacaaact caaaggtgtc gtgaaataca ctattgcaga cggagaggtt gtttacccta
     5341 attaacaaat gagttaaaac aaaaaagctt gactttcaga gaaagtcagg cttttagtaa
     5401 atttattttt taggcacttg tttgcttaaa tttagccccc aaggtattag attttcagta
     5461 tgatgtttga tacgactaat gttatctttg tgtcttataa taataatgaa cgcaagtaat
     5521 atcacaataa aagttaaaaa gtagtcataa tttggtaaaa gaaaatgaat ggcaggaaat
     5581 gttaaaacag ataacacacc aacgatagct gaaaccacac tagctaaaga tatcatgcta
     5641 aataaataga gaactaaaac aaagatagat gctaaaaaaa agagatataa cggagcaaag
     5701 cctagcaata caccagcact tgttgctacg gccttaccac ctttaaagtt ggcaaaaata
     5761 ggaaaagtat gccctaaaac tgcgaaaaag ccgatagcaa tggatgaaat tgaagtcata
     5821 ccaaaaataa ttggtaacaa tattgaaagt gtccctttaa acatatcaat agctaaggta
     5881 gctgttcctg ccttgacacc taaaatccga aaagtatttg tggttccagt atttcctgat
     5941 ccatgctctc gtaagttgat gtggtaaaag tactgtccaa tccatagtcc agttggaata
     6001 gaaccaagta aataggcaat ggtaataaaa agtagtaatt tcataatcct tattataaca
     6061 tattcataga ttggagaact agatctggaa aagaattcgg gaaaaattag caaattattt
     6121 tgcaaaattg gtaaaaaact tgtaagataa aaaagatgaa actgtctgga ggtcggtgtt
     6181 gactaagaac gaaattacaa ttaataatta taatgacgat gctatccaag tcctagaagg
     6241 gttagatgct gttcgcaagc gtccagggat gtatatcggt tcaacagatg ctacgggatt
     6301 gcaccacctg atttgggaaa ttgttgataa tgctgtcgat gaggccttgt ctggttttgg
     6361 agatgatatt aaggttgtta tcaataaaga tggctcggtc agtgtggcag atagcggacg
     6421 tggaatgcca acaggccagc atgccatggg gattcccacc gttcaagtta tttttacgat
     6481 tcttcatgca ggtggtaaat ttggtcaggg tggctacaaa acgtcaggtg gtttgcacgg
     6541 tgttggctcc tctgttgtca atgctttgtc tgcctggtta gaagtcgaaa tcacaagaga
     6601 cgggtcagtg tatcgtcagc gctttgaaaa tggggggaaa cctgttacaa cccttaaaaa
     6661 agttggcaca gctcctaagt ctaaatcagg aacggttgta acatttatgc ctgatgataa
     6721 gattttttca actattgact ttaagttcaa taccatttca gaacgattga aagaatctgc
     6781 ttttcttttg aaaaatgtca agatgagctt gacagatctt cgtggagatg acccgattat
     6841 tgaagagttt cattatgaaa atggggttca agatttcgtc gaatacctca atgaagataa
     6901 ggaaaccttg acacctgtta tttacatgga aggtcaagac caagactttc aagtcgaggt
     6961 tgctttgcag tataacgatg gtttctccga caatatctta tcttttgtaa acaatgtgcg
     7021 caccaaagat ggtggaagcc atgaaacggg actaaagtca gctattacca aagcgatgaa
     7081 tgactatgct cgtaaaacca atctcttaaa agaaaaggat aaaaatctag agggctcaga
     7141 ttatcgagaa ggactctcag cagtattatc tatcttagtt cctgagcagc acttgcaatt
     7201 tgaaggacag accaaagaca aattgggaag tcccttagcg agaccgattg tcgatagtat
     7261 cgtttctgaa aaattaacct tctttttact cgaaaatgga gaagtagctt ctcatctagt
     7321 tcgcaaagcc attaaagcta gagatgctcg cgaagctgct cgaaaagcgc gtgatgactc
     7381 acgtaatggt aagaaaaaca aaaaagacaa aggcttgttg tcgggaaaat taaccccagc
     7441 ccagtccaaa aatgccaaga aaaatgaatt gtatctggtc gaaggagatt ctgcgggagg
     7501 ttcagccaaa caaggacgag accgcaaatt tcaggctatt ttaccattac gtggcaaagt
     7561 tttaaatacc gaaaaagcta aaatggctga catcttgaaa aatgaagaaa ttaacactat
     7621 ggtttatacc attggagctg gagtgggagc taactttaat ctcgaggata tcaactatga
     7681 taagattatt atcatgaccg atgccgatac cgatggtgcc cacattcaaa ccctcttatt
     7741 gaccttcttt taccgttata tgcgaccatt agtagaaaca ggtcacgttt atattgcgct
     7801 tcccccgctt tacaaaatgt caaaaggtaa aggcaaaact gaaaaaattg cttatgcttg
     7861 gactgatggt gaattggaag atctgcgcag agaatttggc aagggggcta ttcttcaacg
     7921 ctataaagga ctgggtgaaa tgaatgctaa ccaattatgg gaaaccacta tggaccctga
     7981 aaccagaacc cttattcgtg ttactattaa cgacttggca agagcagagc gacgtgtttc
     8041 tgtgttgatg ggtgacaaag cagccccacg ccgtcagtgg atcgaggata acgtcaagtt
     8101 taccttagaa gaaaatacgg tgttttagtc atacaagttt ctcacagata attacaagtg
     8161 ctaaagacga ttgtttttta ggtaattaat aaataatgaa aaagaaagct atttgaatat
     8221 gtcaaacatt caaaacatgt cccttgagga tattatggga gaacgcttcg gccgttattc
     8281 caagtatatt attcaggaac gggcacttcc tgatattcga gatggattga aacccgttca
     8341 gcgtcggatt ctttattcga tgaataagga tggcaatact tttgaaaaag gttaccgtaa
     8401 atcagccaaa tcagttggta atatcatggg gaatttccac ccgcatgggg attcctctat
     8461 ttatgatgcc atggtacgga tgagtcaaaa ttggaaaaac cgtgaaattc ttgtggaaat
     8521 gcacggaaat aatggttcaa tggatggtga tccgcctgcg gctatgcgtt atacagaagc
     8581 tcgcttgtct gaaattgcgg gttatcttct ccaagacatt gaaaaaaata cggttccctt
     8641 tgcttggaac tttgatgaca cagaaaaaga accgacagtt ttaccagcag cttttcctaa
     8701 cttacttgtc aatgggtctt ctggtatttc cgcaggctat gcgacagata ttccaccgca
     8761 caatttgtca gaagtgattg atgctgttgt gtatatgatt gatcatccca aagctagttt
     8821 agaaaaattg atggaatttt tgcctgggcc agatttcccg acaggaggca ttatccaagg
     8881 agctgacgaa atcaaaaaag cctacgaaac aggtaaggga cgtgtcgttg ttcgctctag
     8941 gacagaaatc gaggaactta aaggtggtaa acaacaaatt attgtcactg agattcctta
     9001 tgaagttaac aaagcagtct tggtcaaaaa gattgacgat gtgcgtgtta acaataaagt
     9061 cccaggcatc gtagaagtac gcgatgaatc tgatcgcaca ggtcttcgca tagctattga
     9121 gttgaaaaaa gaggctgata gccaaaccat tttgaattat ttgttgaaat acacagatct
     9181 tcaagttaat tacaatttca atatggttgc tattgatcac tttacgccac gccaagtagg
     9241 tcttcaaaaa atcttatcaa gctatatcag ccaccgcaaa gatattatta ttgagcggtc
     9301 taaattcgat aaagccaaag ctggaaaacg cctccacatt gttgaaggat tgattcgtgt
     9361 cttgtccatc ttagatgaga ttattgcttt gattagatcg tctgacaata aggctgatgc
     9421 taaagaaaat ctgaaagtca gctatgattt ctccgaggaa caagcagaag cgattgtaac
     9481 cttgcagctt tatcgtttaa ctaataccga tattgttact ctccaaaatg aagaaaatga
     9541 tttaagagac ttaatcacga ccctttccgc tattatcggt gacgaagcaa ccatgtataa
     9601 cgtcatgaaa cgtgaattaa gagaggtgaa aaagaaattc gccaatcctc gtttatcaga
     9661 gttacaagcg gaaagtcaaa tcattgagat tgacactgcc agcttgattg cagaggaaga
     9721 aacttttgtt agtgtgacac ggggcggata cctcaaaaga accagcccac gatccttcaa
     9781 tgcgtctagt ttagaagaag ttggcaagag agatgatgac gaactcatct tcgttaaaca
     9841 ggccaaaaca acagaacacc ttttgttgtt tacaacttta ggcaatgtca tttaccgacc
     9901 aatccatgaa ttgaccgatt tacgttggaa ggatatcggt gaacatttat cacaaaccat
     9961 ttcaaacttc gcgacagaag aagagattct ctacgctgat attgtgactt cctttgacca
    10021 gggcttgtat gtggctgtca cacaaaatgg ttttatcaaa cgctttgatc gtaaagaact
    10081 aagtccttgg cgaacttata aatctaaatc aaccaaatat gtgaagctaa aggatgacaa
    10141 agaccgcgtg gttaccttgt caccagttat tatggaagac ctcctattag tgactaaaaa
    10201 tggttatgct ttgcgattct ccagtcagga agtgcctatt caagggttga aatctgctgg
    10261 tgttaaaggc attaacttga aaaatgatga cagccttgcc tcagcctttg ctgtgacaag
    10321 taactctttc tttgtcttaa ctcagagggg ttctctcaaa cggatggctg tcgatgatat
    10381 tcctcagaca agtcgtgcca atcgtggact attggtccta cgagagttaa aaaccaaacc
    10441 tcatagagtt tttctggccg gaggcgttca atcagatact tcagctgagc agtttgattt
    10501 gttcactgat atacctgaag aagaaactaa tcaacaaatg cttgaagtca ttagtaagac
    10561 tggtcaaacc tacgagattg ctttagaaac gctttcgtta tcggaaagaa ccagcaatgg
    10621 ctcctttatt tcagacacta tttcggatca agaagtactg gtagctagaa cacgttaaaa
    10681 agagtgaaaa ctctttttaa ttttatggta aatttagaat attaatgcaa aagagtagaa
    10741 taaacttgaa aattattgaa aaaaagttac aatagaaaaa agcagaaaag aggtacgatg
    10801 atgacaatag caattgattg ggacaaccta ggatttgaat atcataagtt gccatttcgt
    10861 tacatttctt attacaaaaa tggtcaatgg gataaaggtc aattaacaga agatgccacc
    10921 ttacatatct cagaaagcgc tccagcgctt cattatgggc aacaagcttt tgaaggttta
    10981 aaggcttatc gcaccaaaga tggctctatt caactattta gaccagaccg taatgcagtg
    11041 cgtttacaag ccacagcaga ccgcttgttg atgccacaag tatcaacaga gcaatttatt
    11101 gatgcagcta agcaagtggt taaagccaat gaagactttg taccacctta cggaacaggt
    11161 gcaacgcttt acctgagacc gttattaatt ggagttggag atattattgg ggttaaacca
    11221 gccgaagaat atattttcac catttttgcc atgccagtag gaaactattt caaaggtgga
    11281 cttgctccga ctaattttat tgtttctgaa gcgtttgacc gcgccgctcc ttacggaaca
    11341 ggtgctgcta aggtgggagg aaactatgca ggaagtttgc taccaggtaa ggccgctaaa
    11401 tcagcaggct tttctgatgt gatttactta gatccagcaa cccatactaa aattgaagaa
    11461 gtcggagctg caaacttttt tggcattact gcaaataatg aatttgttac gccacttagt
    11521 ccatctatct tgccatctat tacgaagtat tcactcttac aactagctga agaaagactt
    11581 ggtatgacag taattgaggg tgatgttcca attaatgaat tggataaatt tgtggaagca
    11641 ggagcttgtg gaacagcagc tgttatctct ccaattggtg gtatccagta caaggataac
    11701 ttacatgtct tttacagtga aacagaagtt ggtcctgtga cacgccgttt atacgatgag
    11761 ttggtcggta ttcaatttgg ggatattgaa gcaccagaag gttggattgt aaaagtagat
    11821 taaaatagag cttgctcttg caagcttttt tgattttgtg taaaatagac aaagtgaggt
    11881 aaagtgatga gtaaaaaaga taaaaaaatt gaaatccaac tgattgatca caaagttatg
    11941 gttaatgaaa ctaagattga tggctatcaa ttacaaattg gtaaacgtgt ggttggagaa
    12001 attgcagaac ttgatgagaa atttgctgtc ttaaaaaatg atggagtaga ttgcttcttc
    12061 aaaacgctcg aacaagcggt tgaaaatatc attgaaaact acaatttgaa ccattaaaat
    12121 tagacaaaaa cacttgccag cttacaaaaa ctatgataga atagtttttg ttgttacgga
    12181 aagatagcga agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt
    12241 cgaatccctc tctttccatt tcggaaacta atctaattag aaaattagtt ttctgtaaaa
    12301 aatatttttg gggtatagcc aagcggtaag gcaagggact ttgactccct catgcgttgg
    12361 ttcgaatcca gctaccccag tcagaggtat caggtgctcc ctgagaccgt caaagataag
    12421 agttgttgtc gttgcgggtt accttgagaa aatatattgt tatcaaaagc tagcattggc
    12481 tagcttttgt tggaggattt tttagaatga atgaatttga agatttgcta aacagtgtta
    12541 gcgaagtgaa ccctggtgat gttgtcactg cggaagtttt aactgttgat aacggtcaag
    12601 caaacgttgt tatcgaagga acaggtgttg aaggtgtctt gacacttcgt gaattgacta
    12661 acgaccgcga tgctgatatt aacgactttg ttaaagctgg cgacacagtt gaagtacttg
    12721 ttcttcgtca agtagtaggt aaagatactg atacagttac tttcctagta tctaaaaaac
    12781 gtttggaagc tcgtaaagcc tgggacaaac ttgttggtcg tgaaggcgaa gttgttactg
    12841 ttaaaggtac ccgtgctgtt aaaggtggtc tttcagttga atttgaagga cttcgtggat
    12901 ttatccctgc ttcaatgatt gacactcgtt ttgttcgcaa cactgaaaaa tttgttggac
    12961 aagagtttga tgctaaaatc aaagaagttg atgcagcaga aaaccgtttc atcctatcac
    13021 gtcgtgaagt tatcgaagag gccgctaaag aagctcgtgc tgaagtgttc tctaagattt
    13081 cagaaggtgc agtcgttaca ggtactgtag cgcgtttaac aagttttggt gctttcattg
    13141 accttggtgg tgttgacgga cttgttcacg tgactgaatt gtctcacgaa cgtaacgtgt
    13201 cacctaaatc agttgtttca gttggtgaag aagttgaagt taaagttctt tcaattgacg
    13261 aagaagctgg tcgtgtgtca ctttcactta aagcaacaac acctggacca tgggacggcg
    13321 ttgaacaaaa acttgctcaa ggtgatgttg ttgaaggtaa agtaaaacgc ttgactgact
    13381 tcggtgcttt tgttgaagta ttaccaggta ttgatggact tgttcatatt tcacaaattt
    13441 cacacaaacg tgttgaaaat ccaaaagatg tactttctgt aggacaagaa gtaacagtta
    13501 aagttcttga agtgaatgca gctgatgagc gcgtatcatt atcaatcaaa gctcttgaag
    13561 aacgcccagc gcaagctgaa ggagacaaca aagaagaaaa acgtcaatca cgcccacgtc
    13621 gtccaaaacg tgaatcaaga cgtgactacg aactcccaga aacacaaact ggattctcaa
    13681 tggctgatct tttcggtgat attgaattgt aataaatcta aaaagttgag gttttcctca
    13741 actttttatt gtcttctggt tagaaaagtt atttcatatt atttca
//
LOCUS       DAUGOH010000040        13587 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUGOH010000040 DAUGOH010000000
VERSION     DAUGOH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13587
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.040"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..1098
                     /locus_tag="VH957_001388"
     CDS             <1..1098
                     /locus_tag="VH957_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8559289.1"
                     /translation="QKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPKLQS
                     SHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVRDLVSGHLERIQE
                     EVEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPDF
                     LANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIGS
                     KVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPRY
                     LRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDIH
                     QTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(1208..2293)
                     /locus_tag="VH957_001389"
     CDS             complement(1208..2293)
                     /locus_tag="VH957_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8559290.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2391..3017
                     /gene="udk"
                     /locus_tag="VH957_001390"
     CDS             2391..3017
                     /gene="udk"
                     /locus_tag="VH957_001390"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEQ8559291.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            3097..3360
                     /locus_tag="VH957_001391"
     CDS             3097..3360
                     /locus_tag="VH957_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEQ8559292.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERKLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(3413..4222)
                     /locus_tag="VH957_001392"
     CDS             complement(3413..4222)
                     /locus_tag="VH957_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEQ8559293.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            4367..4864
                     /locus_tag="VH957_001393"
     CDS             4367..4864
                     /locus_tag="VH957_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEQ8559294.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKESHLIGVLDLDSSLVADYDEVDQEYLEAFVDLLLEKTTFTFNM
                     FGVKN"
     gene            4864..6534
                     /gene="dnaX"
                     /locus_tag="VH957_001394"
     CDS             4864..6534
                     /gene="dnaX"
                     /locus_tag="VH957_001394"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEQ8559295.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISMLALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            6629..6832
                     /locus_tag="VH957_001395"
     CDS             6629..6832
                     /locus_tag="VH957_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEQ8559296.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKAANSPKKKD"
     gene            complement(6807..7748)
                     /locus_tag="VH957_001396"
     CDS             complement(6807..7748)
                     /locus_tag="VH957_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEQ8559297.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFDNGDLQTLRSGEISLSSWEN"
     gene            7952..10330
                     /locus_tag="VH957_001397"
     CDS             7952..10330
                     /locus_tag="VH957_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEQ8559298.1"
                     /translation="MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMMS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADSHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDLAKKAEKPAETHHTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVEIQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNKM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKRLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLRQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            10866..12062
                     /locus_tag="VH957_001398"
     CDS             10866..12062
                     /locus_tag="VH957_001398"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ8559299.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQICQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKIDALVE
                     AVKTVL"
     gene            12236..13495
                     /locus_tag="VH957_001399"
     CDS             12236..13495
                     /locus_tag="VH957_001399"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8559300.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT         4329 a         2341 c         2827 g         4090 t
ORIGIN      
        1 caaaaagact attattattt ttccccgata aaacaagcag atgatttttt tgtagataat
       61 ttacctgttt cattatacaa aaaaaagaat tcagataaag aattgatttt agtaaagcct
      121 aaactgcaat cttctcacct aagatcagtt aacactttga ctatttctaa aatagtttat
      181 cagaaaaaat tttttcattt ggctaaaaaa tcagaaaaag ttataagtac atatcacgtt
      241 acagacgact tgaaaccgtt tcaggtaagg gatctagtat caggacattt agaaagaata
      301 caagaagaag ttgaaaaaaa atatccaaat gctggtttta atagcgataa gtacaatggc
      361 ttaaaagaat ctaattcttt attaagcgat ggctttgagg taaaatcggg aaaccttatt
      421 tttgataaaa agctaacgat acctttgacg acattatttg atgttattaa tccagatttt
      481 ttagcaaata gcgatagagc tgcgtatgat aattatagga cctacaaaga acagcatccc
      541 aaaaaactag ttgcattaac gtttgatgat ggtccagatc cgacgacgac tcctcaagtt
      601 ttagatattt tggcaaaata ccaggctaag ggaactttct ttatgatagg ttcaaaagtt
      661 gtgaataatg aaaaccttac taaacgtgtt agcgacgctg gccatgaaat tgctaatcat
      721 acttgggatc atcccaatct gactaatctt tcagtcagcg agattcaaca tcaagttaat
      781 atgacgaacc aggctattga aaaagcttgt ggcaagaaac ctcgctattt acgccctcca
      841 tacggagcta caaatgcaac tgttcagcaa tcctcaggat taacacaaat gctttggacg
      901 gttgatacaa gagattggga aaatcatagc actgatggca ttatgactaa tgtcaaaaac
      961 caattgcaac cgggaggagt tgttttaatg catgatattc atcaaacaac tatcaatgct
     1021 ttgccgacag ttatggaata tctaaaagca gaaggatacg aatgtgtgac tgtatcagaa
     1081 ctctatgcgc atcagtaagt aatatcgtta tgtttcttta gaattgatat actaaacaat
     1141 ccaattactt tgaagtaatt ggattgttgt ttttagtagc ccttgattaa gttttgtttt
     1201 ttaacaacta gttgatgaaa tgaagttgtt gatttttgag ggagatttca gagactttag
     1261 caaatttttt caattttttg aggtcttcag ggtggctaac aaaggtaata acgataccag
     1321 attttcccat acggccggtt cgtccagctc tgtgagtata attttcctta tcacgagcaa
     1381 catcaaaatg aatgacatag tcaagattat caatatcaat gccccgagca acaagatccg
     1441 tagctaacaa taaggagagt tggtgggatt tgaatttttc gagaatggtt ttacggaatt
     1501 tgacattgat gtcactcgct aaggaaaccg cagcagctcc attatattgg agacgttctt
     1561 ccgtagcacc caaatcagat aaactgttga aaaagactaa agctctaaaa tgaggaatat
     1621 tagcaaattt tcgtaataaa tcggtacgtt cgcgcttgtc aaccatgagg taaaaatgct
     1681 gaatagcatc gttggtttgc tctgaaagat cgatgcagaa tgtatttgga gctaaggaag
     1741 tttgatccac cttattagta gcactcatgt ataccatttg atgatctcga ggaacatagt
     1801 ggctaatttt ttgaacaaaa tcatattggg aatcacctaa tagttcgtca tattcatcta
     1861 aaacaatggt gttgacagac atcatcttga tttttttcaa tttaatcagt tcaaaaatgc
     1921 gtccaggggt cccaatcagg atttcaggac cttttttgag gcgttcgatt tgacgttttt
     1981 gactggttcc agaaataaag agttgtgccg ttaagcctag tggctgtgcc caatcctttg
     2041 tgacttcaaa aatttggcca gctaattcgg tattaggggc taaaatgagt agttgttggg
     2101 actttttagg cgtcagtgcc aatagactag gaaagacata agctaaggtc ttgcccgtcc
     2161 cagtagggct aataccaagg aaatttttac catcaacaat aggttgaaag gcctgttctt
     2221 ggattggcgt taaatgggta aatgcaactt ggtcaagttt ttcttgccat tgagggggaa
     2281 atttagtgat catgcgtctt ccttttacta ttgtttctat attcattata gcattatagt
     2341 ctcaattttg gtaaaatagt gagaaagact ttttagattt ggagtttaaa atgcttaaaa
     2401 aaccgattat tattggtgta actggtggtt caggtggcgg taaaacaagt gtgtcacgcg
     2461 ctattttgga cagttttcca aatgctcgta ttgcgatgat tcaacacgat tcttactata
     2521 aagatcagtc tcacatgagt tttgaagaaa gggtcaaaac caattatgac catcctctag
     2581 cttttgatac agattttatg attcagcaac taaaagaatt attagctggt agacctgtag
     2641 atattcctat ctatgattac aaaaagcata cccgcagtaa tacgaccttt cgtcaggatc
     2701 ctcaggatgt tattattgtt gaaggtattc ttgtcctaga agatgagcgt ttgcgagatt
     2761 tgatggatat caagctcttt gtagacacag atgacgatat tcgtattatt cgtcgtatta
     2821 agcgtgacat gatggaacgt ggcagaagct tagaaagtat tattgatcag tacacaagcg
     2881 tggtaaagcc tatgtatcat cagtttattg agccaagtaa acgctatgct gatattgtta
     2941 ttccagaggg agttagtaat gtcgttgcta ttgatgttat taatagtaaa attgcgagta
     3001 ttcttggaga agtatagtgg aagtggctga gtagattatt taaatctgct cttttattgt
     3061 tgtgctcttc atagagaaag ggatcataaa atagaaatgt tattaatttg gcttggatta
     3121 ctatttgttt ggaatgaact cgtgtttgtc atatatgcct ttgataaaag aaaagccata
     3181 aaaaagaaac ggcgtattag tgaaagaaaa ttattagtga taacagtttt gtttggaggt
     3241 tttggagcat tacttgcagc taaaaagtac caccataaaa ccagaaagtg gtactttgtc
     3301 atcacttggt atactagtat tttgttgaca ttactagtaa cttatatctt tatgaagtga
     3361 gtcacttaaa agacccttaa tcagtattat ttagtcaagg ctcttttata gtttaaaaaa
     3421 gcacatcatc gtcaagggtg ttgatttttt gaaaaagatc accaaagatt aaaaggatta
     3481 atgttcctag taaaactgtc atgccaggaa tgcttgttag aggagagttc cagatgaaat
     3541 gtagaaccag aggacttaat aaccagaaaa tttgttgctg ttttgaaaaa aggttagaac
     3601 cctttaataa taagtatgct ccaatggtaa aaatagctgt atgtacccaa tgtgaagtca
     3661 cagcagtgct aatacgttca atagcagtcg gtacgagact atctatagat tttgcttgaa
     3721 tcaaataacg gatatcttct gttagttgaa agcccatgcc agaaagtaaa gcaacaacta
     3781 atttttcttt aagagtaagt ctaggaaata aagtaattac taaaatagcc gaagaagcct
     3841 taatgggctc ttcgacaata ggggcagtta aagcatctcc ccaaagcttt aaagcgtctt
     3901 tagaagggat gatgtatgac caaaattgtc ctacgagatg gttcccacaa gaagctaaaa
     3961 aacctgaaat ataaagtccg ctaagacagc taacaataat aacgttcagg ttcatatgaa
     4021 attttttact taaataaaaa atagctgctg caaatggaat taagtaaatg cctaatagac
     4081 taatggttag tattagagca aaagcttctt taaaggaaag gttgttagct gtcagtccta
     4141 acaattcaag ttcaatacca tttaaaacta aagcaataaa aagaccgtat cgtaaccatt
     4201 tctgttgagt gatttgtttc acgaaaacct cctaatatta agatgatatt aataatattg
     4261 aaaattatat cataaacaac ctcaaaaacc attttaaaaa ctgactgaag cgaaagatag
     4321 tcgtaaaaaa tactcgaata gacccagata tgctataata aaaggtatga ataagtctaa
     4381 aaaaattgag caataccaac taatgatagc gcaggcaaaa gagctgtttg cgaatgaatc
     4441 aaatgctttg gctaatttgt caaatgccag cgccctgtta aacatgacac tacccaattc
     4501 tgtttttgcg ggattttacc tttttgatgg gcaggaatta attcttggcc cttttcaagg
     4561 tagggtttct tgcgtccata tcaagcttgg taaaggtgtt tgtggcgaat cagctcagtc
     4621 tcgtcgaacc attattataa atgatgtgaa gcagcatgcc aactatattt cctgtgatgc
     4681 ggcagccatg agtgaaattg ttgtgcctat ggtgaaagaa agccatttga ttggggtgct
     4741 ggacttggat tctagccttg tagctgatta tgatgaggtt gatcaagaat atttagaggc
     4801 ctttgtggac ctacttcttg aaaagaccac gtttaccttt aacatgtttg gagttaaaaa
     4861 ctgatgtatc aagctcttta tcggaaatac cggagccaaa cgtttgacga aatggtggga
     4921 caatcggtta tttccacaac tttaaagcag gcagttgaat ctggcaagat tagccatgct
     4981 tatttatttt caggtcctag agggactggg aaaacaagtg cggcaaagat ttttgcaaag
     5041 gccatgaatt gtcctaacca agtcgatggt gaaccctgta atcaatgcga tatttgccga
     5101 gatatcacga atggaagctt ggaagatgtg attgaaattg atgctgcctc gaataatggt
     5161 gttgatgaaa ttcgtgacat tcgagacaaa tcaacctatg cgccaagtcg tgcgacttac
     5221 aaggtttata ttattgatga ggttcacatg ttatcaacag gggcttttaa tgcgcttttg
     5281 aaaactttgg aagaaccgac agaaaatgtt gtttttatct tggcaacaac ggaattgcat
     5341 aaaattccag ccactatttt atctcgtgtg caacgctttg aattcaaagc tattaagcaa
     5401 aaagctattc gagagcattt agcctgggtt ttggacaaag aaggtattgc ctatgaggtg
     5461 gatgctttaa atctcattgc aaggcgagca gaaggaggca tgcgtgatgc tttatctatt
     5521 ttagatcagg ctttgagctt gtcaccagat aatcaggtca ccattgcaat tgccgaagaa
     5581 attacaggtt ctatttccat gcttgctctg ggtgactatg ttcgatatgt ctcccaagaa
     5641 caggctacgc aagctctggc agccttagag accatttatg atagtgggaa gagcatgagc
     5701 cgctttgcga cagatttatt gacctatctg cgtgatttat tggtggttaa agctggcggc
     5761 gacaatcaac gtcagtcagc tgtttttgat accaatttgt ctctctcgat agatcgtata
     5821 ttccaaatga taacagttgt tactagtcat ctccctgaaa tcaaaaaggg aacccatcct
     5881 cggatttatg ccgaaatgat gactatccaa ttagctcaga aagagcagat tttgtcccaa
     5941 gcaaacttgt caggagagtt aatctcagag attgaaacgc tcaaaaatga gttggcacaa
     6001 cttaaacaac aattgtcgca gctccaatcg cgtcctgatt cactggcaag atctgataaa
     6061 acgaaaccta aaaccacaag ctacagggtt gatcgggtta ccattttgaa aatcatggaa
     6121 gaaacggttc gaaatagcca acaatctcga caatatctag atgctctaaa aaatgcttgg
     6181 aatgaaattc tagataacat ttctgcccaa gacagagcct tattgatggg ctctgagcct
     6241 gtcttagcaa atagtgagaa tgcgattttg gctttcgagg ctgcctttaa tgcagaacaa
     6301 gtcatgagcc gaaataatct taatgatatg tttggtaaca ttatgagtaa agctgctggt
     6361 ttttctccca atattctggc agtaccaagg acagattttc agcatattcg taaggaattt
     6421 gctcagcaaa tgaaatcgca aaaagacagt gttcaagaag aacaagaagt agcgcttgat
     6481 attccagaag ggtttgattt tttgctcgat aaaataaata ctattgacga ctaaaactga
     6541 aatacataag ggtaaggttt tgcccttacc cacgttttat ctcgttactt tttttcatag
     6601 tacagtattt ttttgttata ataaagctat gactattcga caatttcttt ttatggcctt
     6661 tgtatgtgcc tttgaaacct atttttttaa tgacctgttg ctctctggaa attatctctt
     6721 cgccttattt tggggcttgt tgctctttag ggatttaaga agagtgcata ccattaatca
     6781 attgactaaa accattttaa aagcggctaa ttctcccaag aagaaagact gatttcaccg
     6841 cttcgcaagg tttgaaggtc accattgtca aattggacaa taaggtgtcc ttgatctgtg
     6901 agatcaatcg caatagcacg tttttcttga ctattttcta taaaggtcac ttgtttatta
     6961 agaacaagtg atttttcttt gtaaactttg acatggtcct tgacaggaat agataagaat
     7021 aatttccaga tgtcaatgat aaggtcattg cgcgtgatag tcggtttttc ggtaaagaga
     7081 gaacctgcct tttgagcaat cgcttctggg aagtcggtga caaaaaagtt gagaccaacc
     7141 ccaataatga catcggtgat taaaccagtt tcaacagaag taatggcttc tgtcagaatc
     7201 cctgcaactt tatggttacc tagatagatg tcgtttaccc atttgatttc tgtatcaatg
     7261 cctgttaatc gcgagatagc tttgacaata ctggaagcaa ccatcatcgt ataaggaggc
     7321 atatcagcat aagggacatt gggttttagg tacatggaca tgtaaatacc accggtgcta
     7381 gctgaaaaaa attgccgatc gaggcgtcct ttggcagctt cttggctagg agctaggtaa
     7441 agccttggag cgctgttatg agcttcgatt ccttgtttgg catctaattg ggtagattgg
     7501 ctgtgagggg tataggtgac tggcatccca agcccttggc taatggtttt gggtaataaa
     7561 atatcacctt gtaccatgcg gtagcccttg tgttttaaag aatcaatttg aatcccctga
     7621 ttttcgagac ttttgatgga tttccaaacg gatgtacgag agatactgag ttgatctgct
     7681 agatattccc cactgacgaa gtcatcggtt tgtgacagta attgataaat tttttctgat
     7741 gttttcatat gtatagtata ttataaaaga tcttattttc aaaggaaaag aaaagttagt
     7801 ttttttgtgt aatgctacta acaacagaaa ctattgtttg ttgaagcttc agagctccaa
     7861 ctcgtcaaca actaatagtt atcctaaaaa gagcttgagg aaaaacaagt gatgtgatat
     7921 acttaaccag ttaaataaaa aggagggttg aatgaaaacg aaaaaagtta ttattttagt
     7981 tggtctattg ttatcatctc agttgacttt gatagcttgt caatcacgag gtaatggtac
     8041 atatcccatt aaaacgaaac aatcacgtaa gggaatgatg tcaaacaaaa ttaaaccgat
     8101 taaaaaaagc aaaaagacaa acaagactca caaaggtgtg gcgggtgtcg attttcctac
     8161 agatgatggg tttattttaa ccaaagactc aaaaatctta tcaaaaacag atcagggaat
     8221 cgttgttgac catgatggtc attcgcattt tattttttat gccgatttaa agggaagtcc
     8281 atttgaatac cttattccaa aaggagcaag tttagctaag ccagctgttg ctcagcaagc
     8341 agctagtcaa gggacttcta aagtagcaga ttctcatcac cattatgaat ttaacccagc
     8401 ggatattgtg gctgaagatg ctttaggcta cacggttcgc cacgatgatc acttccatta
     8461 tattttgaag tcaagcttat caggtcagac acaggcacaa gctaaacagg ttgctactcg
     8521 cttgccacaa accagtagcc ctgtttcaac agctacagct aatggtattc caggcttgca
     8581 tttcccaacc tcagatggtt ttcaatttaa cggtcaaggt attgttgggg taacaaaaga
     8641 cagtatttta gtggaccacg atggtcactt acatcctatt tcttttgcgg accttcgtca
     8701 gggtggctgg gcacatgtgg cagatcaata cgatctcgct aaaaaagcag aaaagccagc
     8761 agaaacccat cacacaccag agctatctga acgtgaaaag gaataccaag aaaaattagc
     8821 ttatttggca gaaaaattgg ggattgatcc atcaactatt aaacgtgtgg aaatacaaga
     8881 cggtaaactt ggtttggaat accctcacca tgaccacgca cacgtattga tgttatctga
     8941 tattgaaatc ggaaaagaca ttccagatcc acatgctatt gagcatgccc gtgaattgga
     9001 aaaacataag gttggaatgg ataccttgcg tgccttaggg tttgatgaag aagtgatttt
     9061 ggatatcgtt cgcactcacg atgctccaac cccattccca tcaaatgaaa aagatccgaa
     9121 taagatgaaa gaatggttag caacggttat taaacttgac ttgggcagcc gtaaagatcc
     9181 tttgcaacgt aaaggacttt cactgttacc caacttagaa actttaggaa ttggctttac
     9241 accaatcaaa gatatctcac ctgttttgca atttaaaaaa ttgaaacggt tactaatgac
     9301 aaaaacaggg gtgactgatt atagattttt ggataatatg ccacagttag aaggcattga
     9361 tatttcacaa aacaatctca aagatattag tttcttgagc aaatataaaa acttaactct
     9421 agtagcggct gctgataatg gtattgaaga tattaggccg cttggtcaat taccaaatct
     9481 caaattcctc gtattgagta ataataagat ttctgattta agcccactgg catcgttacg
     9541 tcaattgcaa gaattgcaca ttgataataa tcagattaca gatttaagcc ctgtttctca
     9601 taaagaatca ttgacggttg ttgatttatc aagaaatgct gatgttgact tagcaacact
     9661 tcaagccccc aaattagaaa cgttaatggt caatgatacc aaggtttctc atttggattt
     9721 cttgaaaaat aatcctaatc tatctagcct atctattaac cgtgcgcaat tgcaatctct
     9781 tgagggtatt gaagcaagta gcgtcattgt cagagtagaa gcagaaggta accaaattaa
     9841 atcgcttgtg cttaaagaca agcaagggtc acttactttc ttggatgtga caggcaacca
     9901 gttgacttct ctagaaggtg ttaataattt tacagcactt gacattttaa gcgtgtctaa
     9961 aaaccaatta acaaatgtca acctatctaa acccaataag acagttacta acattgatat
    10021 tagtcataac aatatcccat tggcagacct taaattgaac gagcaacata ttccagaagc
    10081 cattgcgaaa aacttcccag cggtttacga aggttctatg gtaggtaatg gaacagctga
    10141 agaaaaagca gctatggcta ctaaggcgaa agaaagtgct caagaagcat cggaatcaca
    10201 tgactacaac cataatcatg cctatgaaga tgaagaaggt catgctcacg agcacagaga
    10261 caaagatgat cacgaccatg aacatgagga tgaaaatgaa gctaaagatg agcaaaacca
    10321 tgctgactaa actaatctaa gaataacccg atccaactga atcgtcttaa tgacaccatt
    10381 gttgactatc aagaaaacct caagaataac cttgaggttt ttttgaaata aataggataa
    10441 tgagtgaaaa gaatggcacc taaatgacta aaacatgtta taatagattg ttattgagtc
    10501 ccgataagac ggtctgttga acgaaatgtt ttgagacgtt gttgacttca tttggggaac
    10561 agtcgttctc tctttagcta aattacttcg tctaaggctt attttgtggt gacatcctct
    10621 caacaaggag accggattct ttgtaactca acgctattgt cagacattct ttgtctggtt
    10681 aatggacgct agccactagg tggactagct agttgcctta ctagtaaaac cgtaactgat
    10741 tagctaagtt ggttttggcc acttgacttg ctcaatcagc taggaagaaa ggggtaggca
    10801 acttcttgct ttgtggtcaa tgtgactgaa aaaggaagaa tcaacatatt aggggggaca
    10861 tttttatgtc agaacgtaaa cttttcacgt ctgagtccgt atctgaaggg catccagata
    10921 agattgcaga ccaaatttca gatgctattt tagatgccat tttagcagaa gatccagaag
    10981 cccatgtggc tgcagaaact tgtgtttaca caggttctgt tcatgttttt ggagaaatct
    11041 caacaacagc atacattgat attaaccgtg tggtccgcga caccattgca gaaattggtt
    11101 atacagaagc agaatatggc ttttcagcag aatcagtggg agtacatcca tcacttgtag
    11161 aacaatctgg agatatcgct cagggggtta atgaagctct cgaaagcaga gaaggtgata
    11221 ctgatgacct tagccatatt ggagcgggtg accaagggct catgtttggt tttgccatca
    11281 atgaaacacc agaattgatg cctttaccaa tttccttatc tcaccaatta gtgcgtcgct
    11341 tggcggaatt acgtaagtca ggtgagatta gttatctacg tccagatgct aaatctcaag
    11401 tgacagttga gtacgatgaa cacgataaac ctgttcgtgt ggatacagtc gttatttcta
    11461 ctcagcatga tccagaagct actaatgacc aaatttgtca ggatgtgatt gaaaaagtga
    11521 tcaaggctgt aattccagca gattatttag atgatgacac aaagttcttc attaatccaa
    11581 caggacgttt tgttattgga ggtccgcaag gagactctgg attgaccgga cgtaagatta
    11641 ttgtggatac ctatggaggc tattcacgtc atggtggcgg tgctttttca ggaaaagatg
    11701 cgacaaaagt ggaccgttcg gcttcttacg ctgctcgtta tattgctaaa aaccttgtgg
    11761 cagcaggcct tgcgacgaaa gctgaagtcc aactagctta tgcgattgga gttgctcagc
    11821 ctgtgtctgt tcgcgtggat acatttggaa cttcaacggt tcctgaagct gttttagaag
    11881 ctgctgttcg tcaagtcttt gatttacggc cagcaggcat tattcaaatg cttgatttaa
    11941 aacgcccgat ttacaaacaa acagctgcct atggtcacat ggggagaaca gatattgatt
    12001 tgccatggga gcgtttaaat aagattgatg ctttagtaga agctgtaaaa acagtattat
    12061 aaacgacaac tttattaaaa aagtagagtg agtgaaaaaa tcttactctg cttttttgtt
    12121 attaaataag cctttaaaag ggatgattaa aaattaagac gtcaataatt gtcaggcttc
    12181 atgatttatg ataaaatgaa aaggttgaat tctagtataa gaaagttttg aatgtatgcg
    12241 taaaattatt attaatggcg gaaaagcctt atctggagaa gtggcagttt caggggcaaa
    12301 aaacagtgtt gttgcgctta ttccagcaat catcttagcc gatgatattg tgattcttga
    12361 tggtgtacct gctattagtg atgtagatag tctgattgaa atcatggagc ttatgggagc
    12421 aacagtaaac tatcatggtg atactttaga aattgaccct agaggggtgc aagacatccc
    12481 gatgccttac ggaaagatta atagtcttcg agcttcctat tatttctacg gtagtctttt
    12541 aggccgtttt ggacaagcag ttgttggctt acctggtggt tgcgatttag gaccaagacc
    12601 aattgacttg catttgaagg ccttcgaggc tatgggagtt gaagtgtctt atgagggtga
    12661 aaatatgaat ttatcgacaa atggtcaaaa aattcatggc gctcatatct atatggacac
    12721 cgttagtgtc ggtgctacaa ttaatactat ggttgcggca acaaaagctc aaggtaaaac
    12781 ggttattgaa aacgctgcac gtgagccaga gattattgat gtggctactc ttttgaataa
    12841 catgggtgcg catattcgtg gagcaggtac agatattatt acgatacaag gtgttcagaa
    12901 attgcatggt actagacacc aagttattcc tgatcgtatt gaagcaggga cttatatcgc
    12961 tttggcggca gctattggaa aaggtgttaa gatcactaat gttctttatg agcatttaga
    13021 gagtttcatt gctaagttag aagaaatggg tgtccgtatg acggtagaag aggatgctat
    13081 ctttgttgaa aagcaagaat ccctcaaggc tattacaatt aaaacctctc cttaccctgg
    13141 ttttgccact gatttgcaac agccattaac gcccttgttg ttaaaagcag atggtcgtgg
    13201 aacgattatt gacactatat atgaaaagcg cattaaccat gtgccagagt tgatgcgcat
    13261 gggagcagat atctcagtta ttggtggtca gattgtttat caagggccgt ctcgcctgac
    13321 aggagctcag gtcaaagcca ctgatttacg tgccggagcg gctctagtga ctgctggtct
    13381 aatagctgaa ggcaagacag aaattactaa tattgaattt atcttacgtg gctatgctag
    13441 tatcattgca aaattaacag cactaggggc agatattcaa ttaatcgaag actaaagaga
    13501 agctaacgct tctctttttt atattacatg tgcttaggct aataatactt aggtgcatac
    13561 tttgttgcat tttatggctt tttaact
//
LOCUS       DAUGOH010000041        13560 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUGOH010000041 DAUGOH010000000
VERSION     DAUGOH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13560
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.041"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            385..813
                     /gene="lacA"
                     /locus_tag="VH957_001400"
     CDS             385..813
                     /gene="lacA"
                     /locus_tag="VH957_001400"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8559301.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKHEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            848..1363
                     /gene="lacB"
                     /locus_tag="VH957_001401"
     CDS             848..1363
                     /gene="lacB"
                     /locus_tag="VH957_001401"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8559302.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHEIIDCGTYDNVRTHYPI
                     FGKKVGEAVASGKAELGVVICGTGVGITNAVNKVPGIRAALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            1411..2340
                     /locus_tag="VH957_001402"
     CDS             1411..2340
                     /locus_tag="VH957_001402"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEQ8559303.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNEFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIGIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTRDFDALKEVLQDKLFDGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKIKEV"
     gene            2344..3327
                     /gene="lacD"
                     /locus_tag="VH957_001403"
     CDS             2344..3327
                     /gene="lacD"
                     /locus_tag="VH957_001403"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8559304.1"
                     /translation="MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECSAEDIP
                     FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEG
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLEFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            3351..3668
                     /locus_tag="VH957_001404"
     CDS             3351..3668
                     /locus_tag="VH957_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8559305.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            3668..5365
                     /locus_tag="VH957_001405"
     CDS             3668..5365
                     /locus_tag="VH957_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8559306.1"
                     /translation="MNGLIAQIEKGKPFFEKMSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIESLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFMSTMLAAIVGFLLMAANPAKEGGFLTGFMGTKGLLTAFIAAFITVNVYKTCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHTTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFIWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLVVVDVIIYYPFLKIYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKAQFEN"
     gene            5453..6859
                     /gene="lacG"
                     /locus_tag="VH957_001406"
     CDS             5453..6859
                     /gene="lacG"
                     /locus_tag="VH957_001406"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEQ8559307.1"
                     /translation="MTKTLSKDFIFGGATAAYQVEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGTNVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            7335..7490
                     /locus_tag="VH957_001407"
     CDS             7335..7490
                     /locus_tag="VH957_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEQ8559308.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            7572..9875
                     /locus_tag="VH957_001408"
                     /pseudo
     CDS             7572..9875
                     /locus_tag="VH957_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018223.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
     gene            9872..10609
                     /locus_tag="VH957_001409"
     CDS             9872..10609
                     /locus_tag="VH957_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559309.1"
                     /translation="MNQLLLKNVCKRYPNQPNYALDHINLTVRKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISAFSDNEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNVDSSKINDLINNYAKRFNLYEQLEKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHLEIDKEDCGETFYDVISQALSDRGE"
     gene            10611..12518
                     /locus_tag="VH957_001410"
     CDS             10611..12518
                     /locus_tag="VH957_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8559310.1"
                     /translation="MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIIT
                     EKIGDSGQALVIANGSLVFLTVFLVIFLIYFNNFFVKKRSQELGVLAILGFSKKELTQ
                     LLTLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITANEIIESLGIL
                     VVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLAT
                     VFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKGNKKRLYRPLSNI
                     IYPKFNYRIATKNKLLTVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVES
                     ENGQVNVTTILENDQVSLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKA
                     QGRINSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTL
                     VVSDKLYAKLSSCFPEKEMTIRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTA
                     NIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYE
                     TGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVL
                     TLRSVTSIIKN"
     gene            12558..>13560
                     /locus_tag="VH957_001411"
     CDS             12558..>13560
                     /locus_tag="VH957_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559311.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIIFIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNRILFNFLFLMVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWMVLMKVLVKDFL
                     LFFIIVDASTLFCLVVISCIFYYLENSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     "
BASE COUNT         4567 a         1984 c         2596 g         4413 t
ORIGIN      
        1 taaaaaaatc aaacaaaaca aacataaaca ttggaaaaaa caaaaattaa caaaatagaa
       61 aatgttttaa ataaaacatt tgcaataaat agagataagg gtttcgtaat atatgatagg
      121 ttacgagtgg ctgtcaaagg gatttatgaa atgaaaaaga aacacaagaa acattaggat
      181 aataacataa aaacgaaaaa aataaacatt ttttgtttat tttttgtaag aataaacaaa
      241 aaatgttgac ttttatgttt ggtgggtgta tgattaggtc atagaaataa tgaaagcgtt
      301 atttcaaaag atgttgcaaa tcgttaatta actatctacg taggttttcc acatttactt
      361 attctaaatc ataggagaaa taaaatggca attattatcg gtgctgacaa agcaggtcaa
      421 gaacttaaag aagttatcaa agattacctt aaagaaggta aacacgaagt cgttgatgtt
      481 agtgaaaacg aagtacgtga ctttgtagat acaactttag ctgttgcaaa agaagttaat
      541 gcatccgaag ataacttagg tattgtcatt gatgcatatg gtgttggttc tttcatggta
      601 gctactaaaa tcaaaggaat ggtggcagct gaagtatcag atgagcgctc agcatacatg
      661 acaagaggac acaacaatgc tcgaatcatc acgcttggtt ctgaaattag tgctccagga
      721 attgcaaaga acattatcaa aggctttgtc gaaggtaaat atgatggtgg acgtcatcaa
      781 gttcgtgtcg acatgcttaa taaaatgtgc taattgattg aaataggtta aaacaaggag
      841 aacaaaaatg aaaattgctg taggttgtga ccatattgtt acttatgaaa aaatcgctgt
      901 tgtggattac ctaaaatcac aaggtcatga aattattgat tgcgggacat acgataatgt
      961 ccgcacacac tatccaatct ttggtaaaaa agttggtgaa gcagtagcaa gtggtaaagc
     1021 agaattaggt gttgttatct gtggtactgg tgttggtatc acaaatgctg taaacaaagt
     1081 tcccggtatt cgtgcagcac tcgttagaga tatgacatct gctatctact caaaagaaga
     1141 gctaaacgca aacgttattg gttttggtgg aaaaatcatc ggtggtttat tgatgaatga
     1201 tattatcgat gctttcttag ccgcggaata caaaccaact gaagaaaata aaaaatggat
     1261 tgaaaaaatg gatagcttgc aacatgctag ccaagatcaa aacaacccac acttctttga
     1321 tgaattccta gaaaaatggg accgtggtga atatcacgac taatatttga ataaattact
     1381 atagggatat atatagaaaa aggagctatt gtgattttaa cagttacttt aaatccagct
     1441 attgacgtct cctacccttt ggatgagcta aaatgcgata ctgtcaatcg agttgtagac
     1501 gttacaaaga cacccggtgg taaaggcttg aatgtttccc gagttcttaa tgaattcggt
     1561 gaaacagtca aagctactgg ttgtataggt ggagaaagcg gtgattttat cattaatcat
     1621 cttcctgatt cgattttaag tcgcttctat aaaatttcag gtgatactag aacttgtata
     1681 gccattttac acgaaggtaa tcaaacggag attttagaaa aaggaccgat gttaagtgta
     1741 gatgaaattg atggatttac tcatcatttt aagtatttac tgaatgatgt tgacgtagtg
     1801 acgctctcag gcagtctgcc tgctggtatg ccagatgatt actatcagaa gttaatcggt
     1861 attgccaatc ttaatggtaa gaagactgtt ctagattgtt ctggaaatgc tttagaagca
     1921 gtactaaaag gtgatagtaa accaacagtt atcaagccta atcttgaaga actttctcaa
     1981 cttctaggta aagaaatgac aagagatttt gatgccttaa aagaagtctt acaagataag
     2041 ttatttgatg gaattgaatg gataatcgtt tctctcggtg ctgatggtgt atttgcaaag
     2101 cacaaggata cgttttataa cgttgacatt cctaaaatta aaattgtaag cgctgtaggt
     2161 tcaggggatt ctacagtggc aggtattgct tcaggtttag cgaatgatga agatgatcga
     2221 gctttattaa caaaagcaaa tgtcttaggg atgttaaatg cgcaagaaaa aacaactggg
     2281 catgttaaca tggcaaatta cgataagtta tatcaatcta ttaaaatcaa agaggtataa
     2341 aaaatgacaa ttactttaac tgaaaacaaa cgtaaaagca tggaaaaact aagtgtagat
     2401 ggtgttattt ctgccttagc ttttgaccaa cgtggagctc tcaaacgtat gatggctcaa
     2461 catcaaacaa aagagccaac agtagaacaa attgaagagc ttaaaagttt agtttctgaa
     2521 gaactaacac catttgcatc ctcaattcta cttgatcctg aatatggctt gccagcaagt
     2581 cgtgttcgtt cagaagaagc aggcttgttg ttggcatatg agaaaacagg atacgatgca
     2641 acaacaacta gtcgcttacc tgattgctta gatgtttggt ctgcaaaacg tattaaagaa
     2701 gctggagcag aagcagttaa attccttctt tactatgata ttgatggaga tcaagatgtt
     2761 aacgagcaga aaaaagctta cattgaacgt attggttctg aatgcagtgc agaagatatt
     2821 ccattctact tagaaattct aacttatgat gagaaaattg ctgacaatgc aagccctgag
     2881 tttgcaaaag ttaaagctca taaagttaac gaagcaatga aagttttctc aaaagagcgc
     2941 tttggtgttg acgtgttgaa agttgaagtt ccagtaaata tgaaatttgt agaaggcttt
     3001 gcagatggtg aggttctctt tacaaaagaa gaagcagctc aagcttttcg tgatcaagaa
     3061 gcttctactg atttaccata catttatttg agtgctggtg tttcagccaa gttgttccaa
     3121 gatactttgg aatttgcagc agaatcaggt gctaaattca acggtgtctt atgtggacgt
     3181 gctacctggg caggatctgt aaaagtctat atcgaagaag gaccacaagc agctcgtgaa
     3241 tggttgcgta cagaaggttt caaaaatatt gacgaattaa acaaagtact agataaaact
     3301 gcaagtcctt ggactgaaaa aatgtaacat tattttcgga ggaaactaca atgaatagag
     3361 aagaaactac tcttttaggt tttgaaatcg tagcctatgc tggtgatgct cgttcaaaat
     3421 ttttggaagc gcttaaagca gcgcaagaag gagattatgc taaagcagaa gaattaatcg
     3481 ctgcaggtag tgactgcttg aatgatgctc acaatgctca gacaagtcta ctacaaaaag
     3541 aagcagctgg agatgactta gcttatagtg tcactttaat gcatggtcaa gatcatttaa
     3601 tgacgaccat tttattacaa gatttaatga aacacatgat tgaactttat aagagaggag
     3661 caaaataatg aatggattaa ttgctcagat tgagaaaggg aaacctttct tcgagaaaat
     3721 gtctcgaaac atctatcttc gcgctattcg tgatggtttt atcgctggta tgccagttat
     3781 cttgttttca agtatcttta tcttgattgc ctatgttcca aatgcatggg gcttccattg
     3841 gagtaaggat attgagagtc tcttgatgac gccatacaac tactcaatgg gtattttagg
     3901 tttgtttgtg gctggtacga cagccaaagc tttaactgac tcaatgaatc gatcattacc
     3961 aagcacaaac caaatcaact tcatgtctac catgctcgct gctattgtag gttttttact
     4021 tatggcagcc aatccagcaa aagaaggtgg tttcttaact ggatttatgg gaacaaaagg
     4081 tttgttgaca gccttcatcg cagcttttat taccgtaaat gtctataaaa cctgtgtgaa
     4141 aaacaatgtt acaatccgta tgccagaaga ggttccacca aatatctctc aagtatttaa
     4201 ggatttgatt ccatttacgt tatcagttgt actgctttat gtgattgaat tgattgttca
     4261 tactacttta ggcgttaacg ttgcagaatc aattggtaaa cttcttgcac cattgttcca
     4321 agcagcagat ggctatgttg gaatcactat tatcttcggt gcatttgctt tcttctggtt
     4381 tgttggtatt catggaccat ctattgttga accagccatt gcagcgatta cttacgcaaa
     4441 tgctgaaacc aaccttcaat tacttcaagc tggtgaacat gctgacaaga ttttgacttc
     4501 agggactcaa atgttcatcg ttaccatggg tggtactggt gcaactctcg tcgttccatt
     4561 catgttcatt tggttaacaa aatcaaaacg taacaaagcg attggacgtg catcggttgt
     4621 tccaacattc tttggtgtta acgaaccaat tttgtttggt gccccacttg ttttgaaccc
     4681 aatcttcttt attccattta tcttggcacc aattgtcaat gtatggattt tcaaattctt
     4741 cattgacaca cttggaatga acagtttcac tgcaaactta ccttggacaa caccagctcc
     4801 attgggtctt atccttggta caaacttcca agtgctagca ttcattttgg cagctttgtt
     4861 agttgttgtt gatgtgatta tctactaccc attcttgaaa atttatgatg agcaaattct
     4921 tgctgaagaa gcagcaggta cgaattcatc agatgccctc aaagaaaaag tagcagcaaa
     4981 ctttgatact aaaaaagctg atgctattct tgaaaaatca gcagctaaag aaaccaaaga
     5041 aatcactgat caaactaatg ttctcgttct ttgtgccggt ggtggtacaa gtggtttgct
     5101 tgcaaacgct ttgaataaag cagctaaaga atatggtgca cctgtcactg cagcagcagg
     5161 aagttatggt gctcaccgtg agattttacc acaatatcaa cttgttatcc ttgcacctca
     5221 agtagcttct aactatgaag atatgaaagt ggaaactgat aaacttgata ttaaattagc
     5281 taaaacagaa ggggctcaat acatcaaatt gacccgtgat ggtcaaggag ctcttgattt
     5341 tgtaaaagca cagtttgaaa attaagaaaa cagtttaaat gtcgtaaagt tctcaaacac
     5401 aaaaattgtt ttgggaactt tatttttgaa agatattcaa ggagaaactg agatgacaaa
     5461 aacattatct aaagatttta tttttggtgg tgctacagct gcttaccagg ttgaaggtgc
     5521 tacccataca gatggcaaag gaccagtagc ttgggataaa tacttagaag acaactattg
     5581 gtacacagct gagccagcaa gtgattttta taatcgttac ccagtcgatt tgaaacttag
     5641 tgaagaattt ggtgtcaacg gcatccgtat ctctattgcc tggtctcgta tttttccaac
     5701 aggaaaagga gaagttaacc ctaaaggagt tgaatactac cacaatctct ttgcagagtg
     5761 tcataagcgt catgttgagc cttttgttac acttcaccat tttgatacac cagaagctct
     5821 ccactcggat ggtgatttcc tcaatcgtga gaacattgaa cattttgtaa attatgcaga
     5881 attttgtttt aaagaattct cagaagttaa ctattggaca acatttaacg aaattgggcc
     5941 tattggtgat ggccaatact tggttggtaa attccctcca ggtatccaat atgatcttgc
     6001 taaagttttc caatcacacc ataacatgat ggtctctcat gctcgtgcag tcaaactctt
     6061 taaagatagt ggttattcag gtgaaatcgg cgttgtccat gctcttccaa ctaagtatcc
     6121 atttgacgct aacaatcctg atgatgttag agcagctgaa ctggaagata tcatccataa
     6181 taaatttatt cttgatgcaa cttatctagg taagtattca gataaaacaa tggaaggtgt
     6241 taaccatatc cttgaggtaa atggtggtga acttgatctt cgtgaggaag attttgctgc
     6301 actagacgct gcaaaagatt tgaatgactt ccttggtatt aactattata tgagtgattg
     6361 gatgcaagct tttgatggtg agactgaaat cattcataat ggtaaagggg aaaaaggcag
     6421 ctctaaatac caaatcaagg gtgtgggtcg aagaaaagct cccgttgatg ttccaaaaac
     6481 ggactgggat tggattatct tcccacaagg cttatatgat caaatcatgc gtgtcaaagc
     6541 cgattatcct aactacaaga aaatttatat cactgaaaat ggtcttggtt acaaagatga
     6601 gtttgtagat aatactgttt atgatgatgg acgtatcgat tatgtgaaaa aacacttaga
     6661 agttatttct gatgctattt ctgatggtac aaatgttaaa ggatacttta tgtggtcact
     6721 gatggatgtc ttttcatggt caaatggcta tgaaaaacgt tacggtctct tctatgttga
     6781 ttttgaaact caagaacgtt atcctaagaa gagtgcctac tggtataaaa aagtagcaga
     6841 aactcaagtg attgaatgat tttgagatac ttttttaata catttttaca cgtcatgctc
     6901 gtagtcacaa aaagtagatg atgttgacat tttccaagca tagtattatt tgctgttgat
     6961 ggtaatccat tagttgtaag atcgggttat aagtgttttt agttggtgaa aatgggtttt
     7021 gaaagtttta tttaacatcc tttttcagat atttgacttc tgtcattcaa actcctgacc
     7081 tgattaaata agtaaagtaa ccattttctg attagagatt gatgttatag cgagaagcga
     7141 ttagattgta aaatagctgt aaagaacgag ttttgttttt tatatcagag ggctacttct
     7201 tatgtgacat ctcaaaaatc ttactaaaaa atatgaaaaa agtcattttt gcacttttta
     7261 ctcattgaaa atgatgacgt attatttaca ataaaagtgt agaaaatagt cactacatac
     7321 tgatagaaag gagaatgagt tttatgaaaa attcaaagga tattttgact aatgctatcg
     7381 aagaagtttc tgaaaaagaa cttatggaag tagctggtgg taaaaaaggt tcaggttggt
     7441 ttgcaactat tactgatgac tgtccgaact cagtattcgt ttgttgttaa ttaaaacaat
     7501 ctggataagc agactaaaat ttcctgttta gacttagtct aggcaggatt tttaagtagt
     7561 ggtaggaaaa aatgataaaa agaaatgaat taaagttaga atatcagcaa catcagtttt
     7621 acgagtactt taactcaatt tttgattacg acatattaga tacttctatt agtgaaaata
     7681 tttatttgtt aagggaaaag acacataagt tattttatag tgagtttgaa aatcagttat
     7741 ttgaaactat aatgtttctt tcaatgaaaa cactagttct agatataaat catttttcca
     7801 aggaaattga aaacaagtca aaggcatatg aacaatatat acagcagata agggaagaaa
     7861 atgggataag taattttttt gacagatatc catatttgct aaaacaaatc aatagagaag
     7921 ttggattggt agtggaatca tactctttgc tatttgatag gtttttaaaa gatttgtctg
     7981 aaataaggtc atgctttaat attactgagt ccttaagtaa tgttgaattt tcacttggag
     8041 acagtcattc ccaaaaacaa acagtcgtta agattgaatt taaagggaaa tccgtttact
     8101 aaaagcctaa aagctatgat tcatacaaca tcttgttgga acttattagt ctattgaaat
     8161 ctaataatat accttcgttc agtcttcctg aaagcttaat taaagcggat tattgttggc
     8221 aacttggtgt agcttataca agttccaata aagatgaagt agcgaaaatt tactttaagt
     8281 atggtgtttt agcagcattt tctgaaatat tttctattac ggacttacat atggaaaatg
     8341 tgattgtttc aggcggagat ttatatttaa ttgacgttga aacctttttt caaagaaagt
     8401 tgaatgtaca aaatcagaat tttgaaggga ttactgtaga cacctatcag agaatttata
     8461 agacatcact ttcaaatggt ttatttcctg tacaatttga gaaaaacagc gctcctaacg
     8521 tttctgggat aagtggaaaa ggtgggaaaa gaaaaaaggg aaagtatgaa ctgataaata
     8581 aaaatcgtgg agatatgaag ttagtgaaaa ctgactattt tcaggaagat ggttataata
     8641 ttccgacatt aaatgggaaa gtggtagagc ctcttgacta tgctaatgag atcatttcag
     8701 gatttagaga gtgctacata tttcttctat cacaacgttc aaagattaaa ggaatagtag
     8761 aaggttttcc agaattgaaa agcagagccc tatttcgaaa tacttccgac tatggaaaat
     8821 ttttgcaagc ttctacgaat ccaaagtatc ttttctcaga aaaaaagagg aagaatttat
     8881 tttcgatact atatgaggca aaacatattg aacattttat tgttgataat gaaattaaag
     8941 atttgatgaa tggtgatatt ccttactttt caatggatac cagaggaaac gtctataatt
     9001 ctgtagggac attaattgga aatctaggag atacaacctc gttatttgat agtataacta
     9061 ttttgaacga tgaaagattg aagttcactt gtgaattgct tgaaatagtc tagaaaaaac
     9121 cgattaagca ttgggagagg gaaaagggca aatcttatca gtttttatca atctcctcag
     9181 aacacaattt tagtgaggaa atcttagaca gcattagacg aatatttatt gatgcagata
     9241 agaatagctt ttcttcagag gaggagataa catggctcaa tattgatatt acagagactg
     9301 agcaatgggt aatatctcct cagaacatta ccttctctaa aattgataaa actgatttta
     9361 ggaatatatc ggcttttgta tctcaagatt ctccaatatt tgatggggat gtgatgtata
     9421 acatttcgct aggaagagaa tctgttacag aaaaacaagt tattgaaacc tgtaaaaggg
     9481 tatcactata tgaggatatc aggagtatgc caatgaagtt tcatacccca ctttttcgag
     9541 acaatccatc actatctggg gggcaaaaac aacgaatttc tctagcaaga gagttagtaa
     9601 ctacccctag aatcttagtt cttgatgaac ctacatcagc tttagatgta aaaactgaaa
     9661 gaataatcca aaaaaatgtt gaggctttac attgtacgag ggttttggtt acccatagac
     9721 ttaatacagt tgaaaaagct gataagattt taataatgga taatgggaaa attattgact
     9781 atggtagtca tcattgttta tataaaaata atgagtacta tcgtgattta tatgattcgt
     9841 acatgaacaa ctatcaggag gaagggataa aatgaatcaa ttactattga aaaatgtttg
     9901 caaaaggtat ccaaaccaac cgaattatgc tttagaccat atcaatttga ctgttagaaa
     9961 aggagaattt gtagctgtca tgggacgtag tggtagtgga aaaacaacac ttttaaatgt
    10021 tacttcaatt attgataaaa ttgatagtgg gagtatttat tgtgcagaca aagaaattag
    10081 tgcattttct gataacgagg caactagttt tagaaaaaat gatattggtt ttgtttttca
    10141 agattatatg ctgttagaca gtctaaccat tagggagaat atttctgttg ctctatcttt
    10201 aaaaaatgtt gattcatcaa aaattaatga tttgataaat aactatgcaa aaagatttaa
    10261 tttatatgag cagttggaaa aatatccgta tcaactttct ggaggtcaaa gacagagggt
    10321 cagtattatc agagcaatca ttaaagaacc agagattatt tttgctgacg aaccaactgg
    10381 agcacttgac ttgaaatctt ctgaggaaac aatgatgatt ttgagtgaaa tcaataaaac
    10441 agaaaaggta actattttaa tggttactca tgacgtttta tcagcttctt atgcggatag
    10501 agttgtactt ctcaaagatg gtaaacttca cctggagatt gataaagagg attgtggaga
    10561 gacgttttat gacgtaatta gtcaagcctt atccgataga ggagagtaat atgatttggt
    10621 ccattacaaa atctaacatc aaaaaaaact tttcgttata tcgtatctat tttctagcta
    10681 cgattggttt attaagtatt tttatagctt ttctaaattt tatctcagat aaaatcatta
    10741 cagaaaaaat tggggatagt ggtcaagctc tagttattgc taacgggtca ttagtttttt
    10801 tgactgtatt tttggtgata tttttaattt atttcaataa tttctttgta aaaaaacgta
    10861 gtcaagagct tggagtctta gcaatactag ggttttcaaa aaaagaatta acacaattac
    10921 tgactttaga aaatcttgtt attctagttt taagttactt ggtaagttta ctattgggac
    10981 cgaccttata ttttttagcg gtactggtaa ttactcatct attggaatta acattggaag
    11041 ttcagtggtt tattacagct aatgagatta tagagtcttt aggaatatta gtcgtagttt
    11101 ttctgattaa tgtcatcaca aatggactta tcattagtaa acagtctttg attgaatttg
    11161 ttaatttctc aagaaaggct gagaaaaaaa ttaagataag aaaagtcaga gctattattg
    11221 ctatcactgc attgctattg tcatatattt tatgtttggc gacagtgttt tcatccacac
    11281 gaaatatgct attaagcata gggatggtac cggtttctct attgataatt gtcttagttg
    11341 ttttaggaac agtgttcacc atcagatatg gattggcttt tgtagtttcg ttattaaaag
    11401 gaaataaaaa aaggttatac cgtcctctgt ctaatatcat ctatcccaaa tttaactatc
    11461 gtattgcaac aaaaaataaa ttattaacag tcttgggagg tcttttaaca gtaaccgttt
    11521 cagttgccgg aatgatggta atgctctatg cttattctct taatgggata gagaggttga
    11581 ctccatctgc catagaatat aatgttgaat cagaaaacgg tcaagtcaat gttacaacta
    11641 ttttagagaa cgaccaagtg agcttggttg atgttgacct attgagattg aacactaacc
    11701 cagaagtaac tatcacagaa tctgggcaaa caattcctta ttttgatata attaattaca
    11761 gtgattataa agagttaatg aaagctcaag ggagaataaa ttctattgaa ggtagtaagt
    11821 cactcccatt gttaataaat tattatccaa cagaaattag ccttggaaaa acctttaact
    11881 taggaaatgc atatgatgtt actgtaaaac aagtatcaac gcataatgtt tttagttttt
    11941 ctacaagtgt cacgaccttg gttgtttctg ataaattata tgctaaactt agttcttgtt
    12001 ttccagagaa agaaatgaca attaggactt ttaatggaaa ttcgattagg tcaagtgaag
    12061 cattttacaa tcagtttagt atggttcctg atgttatcag tagttatagt aaggaataca
    12121 cagtaaagac tgctaatatt gcgacttata tctttataac tttcctatcc atactcttta
    12181 ttatttgtac aggtagtatt ctgtacttta caagcctcat cgaaatcatg gaaaataaag
    12241 aagaatatgg ctatctaagt aagctaggtt atagtaaaaa aatgattcat cggattcttc
    12301 gatatgaaac aggtatactt ttccttattc ctgtattcat tgggattgta aatggtggta
    12361 tgttgcttat ttactataaa tatttattca tggatacatt ggtagcaggc aatatcataa
    12421 tgttatcttt attgctttgt ctgcttttct tcttgataat atatggcaca ttttatgtat
    12481 tgacattgcg gtcagtgaca tccataatca aaaattaatt ttaaaaatct tttaacttta
    12541 acgattaagt aaataatatg ataagaataa aaaacataac aaagagtaag ttctttggga
    12601 ctgcaataat cttgttgcaa caattaatag ccttgttaat tttggtctat aatcgagaga
    12661 acctgtctct tcttttctct gaaaaagtag ctcttgtaat gacccttatt gatacagctt
    12721 ttatttggct ggcaacaata ttacgccaaa aacaaggtga tatttttaaa aggattattt
    12781 ttatcatctc cttaacaatt tggcaatact tagtatctgt gctgacaaga ggaactcctc
    12841 tctttttaag cagtggacta cagattatat tgctctattg ttataccgtt gagattacta
    12901 atttaatatt atatgggcac aaacaattta aagataagtt agataagggc ttgttaataa
    12961 ttatttttgt ttctataact agcctttttg ttaatagaat tttatttaat tttttattcc
    13021 tgatggtttt tactatttta cacctgtatc cgttactagt tatagtgcta tattataggt
    13081 cctttaggca acaaatatca gttgttagac gttcattgat actattttct ttacttttgc
    13141 tggtaatact tggtagtgaa ctttatggag aaatgctaga tgttaatcaa gcctttaata
    13201 atttgggatg gtatctgttt ccccttataa tgagtgtaat atactatttt aagaccatac
    13261 atgataaatt gagttttgtt acccaaagat ggttaggtga ttacaaagct cgtatagaac
    13321 tattatttct acttcttatc ctttgttgga tggtactcat gaaggtatta gttaaagatt
    13381 ttttattatt ttttataatt gttgacgcaa gcacgttatt ttgtctagtg gtaatttctt
    13441 gcatctttta ttatttagaa aactctaaac aaaattttga ctatgaaaat agaagactga
    13501 actattttat gaaatcagag gaaaacatga gagtggagtt ctcaaattat ttgcatgatg
//
LOCUS       DAUGOH010000042        13249 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUGOH010000042 DAUGOH010000000
VERSION     DAUGOH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13249
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.042"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            537..1064
                     /locus_tag="VH957_001412"
     CDS             537..1064
                     /locus_tag="VH957_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEQ8559312.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1064..2182
                     /gene="yqeH"
                     /locus_tag="VH957_001413"
     CDS             1064..2182
                     /gene="yqeH"
                     /locus_tag="VH957_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEQ8559313.1"
                     /translation="MEELFCIGCGIQIQTEVKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2207..2515
                     /gene="yhbY"
                     /locus_tag="VH957_001414"
     CDS             2207..2515
                     /gene="yhbY"
                     /locus_tag="VH957_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEQ8559314.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2584..3216
                     /locus_tag="VH957_001415"
     CDS             2584..3216
                     /locus_tag="VH957_001415"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEQ8559315.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3213..3806
                     /gene="yqeK"
                     /locus_tag="VH957_001416"
     CDS             3213..3806
                     /gene="yqeK"
                     /locus_tag="VH957_001416"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEQ8559316.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3830..4183
                     /gene="rsfS"
                     /locus_tag="VH957_001417"
     CDS             3830..4183
                     /gene="rsfS"
                     /locus_tag="VH957_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEQ8559317.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILILDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            4231..4974
                     /locus_tag="VH957_001418"
     CDS             4231..4974
                     /locus_tag="VH957_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8559318.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            5228..6334
                     /locus_tag="VH957_001419"
     CDS             5228..6334
                     /locus_tag="VH957_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEQ8559319.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFISVQSADYFAQGAIDILCQLGIQQLAFGTENVID
                     YQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6816..7532
                     /locus_tag="VH957_001420"
     CDS             6816..7532
                     /locus_tag="VH957_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8559320.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7735..8577
                     /locus_tag="VH957_001421"
     CDS             7735..8577
                     /locus_tag="VH957_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8559321.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8904..9749
                     /locus_tag="VH957_001422"
     CDS             8904..9749
                     /locus_tag="VH957_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8559322.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKTKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9999..11063
                     /locus_tag="VH957_001423"
     CDS             9999..11063
                     /locus_tag="VH957_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559323.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSANALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQKFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11064..11756
                     /locus_tag="VH957_001424"
     CDS             11064..11756
                     /locus_tag="VH957_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8559324.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11810..13180)
                     /gene="brnQ"
                     /locus_tag="VH957_001425"
     CDS             complement(11810..13180)
                     /gene="brnQ"
                     /locus_tag="VH957_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEQ8559325.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFSDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
BASE COUNT         4362 a         2079 c         2759 g         4049 t
ORIGIN      
        1 ggtaaatcta tgaaaaaagt gtaatcattt tttgatttac agttattatc atgtgttatc
       61 tggcgactgt cctgtttaca agtaagttca caagtatggg ataaaatagt ataaactata
      121 gtaaatactg aatagtcaaa gaaaaatatc ggcataggtc agaagagctg atatgtttaa
      181 tactttttgc ggatatctac tgtatttaaa tgtatttgat atccttgtca aggatatacg
      241 tctaaacaag ttcaaaacga aatcatttgt gattatctta tcaggagttg actcttgata
      301 agatttttgt atatcagtac tgtggtacgt ttagatagct tggcagtgaa tttatagagt
      361 gtcaaacaac gagtgttttg tgttacacta accattagaa gagtctattg ttgagcatat
      421 caaggtgtta tcttttcgag ttgaggtatc atatctagta tatttaacta tggttttaaa
      481 tgctatttca aaaaaaatat gataaaatag aaagtactaa ttattttgga gatgacatga
      541 gtatcgatga ttataggccg acctatatgg tagaggctat ttatgattta agagcaaatg
      601 atttgttgcg tcatggtatt acggctgttt tagtggattt agataatacc ttaattgcat
      661 ggaataatcc tgatggcaca ccagaggttc gcgcttggct tgatgaaatg actatcgcgg
      721 atattagcgt ggttgttgtt tcaaataata aacattctcg tgttgagcgt gccgtttcac
      781 gctttggtgt tgactttatt agccgggctt tgaagccatt tgcttatggt attgaaaaag
      841 ccattgctcg ttatggattt gatcgcaacg aggttatcat ggttggagat cagctaatga
      901 ctgatatcag agctagtcat agagctggaa taaaatcagt tttagtcaaa ccacttgttg
      961 cttctgatgc ttggaatact aaaattaacc gctggcgtga acgccgtgtg atggcaaaat
     1021 tagaagagaa atatggtaaa ttatcatatc aaaaaggaat ttaatggaag aattattttg
     1081 tataggctgt ggtatccaga ttcaaactga agttaaagaa aaagctggtt ttacgccagc
     1141 tgctgctttg aaaaagggta tggaaacagg agaactctat tgtcagcgct gctttagatt
     1201 gaggcattat aatgaaatta cagatgtcca tattaccgat gatgaatttt taagacttct
     1261 tcacgaagtg ggtgatagtg atgctcttgt ggttaatgtg attgatattt ttgactttaa
     1321 tggttctatt attccaggtc tatctcgctt tatttctggc aatgatgtct tactggttgg
     1381 gaataaaaaa gatattttgc caaagtctgt taaggatggt aaagttactc aatggttgac
     1441 ggaacgtgca cacgaagaag gtcttcgccc tttagacgtt atgttaacaa gcgctcaaaa
     1501 taaatatgcg atcaaagact tgattgagcg tatcaatgag ttacgtaatg gtcgagatgt
     1561 ttatgttgtg ggggtcacta atgttggtaa atcaaccttg attaatgcga ttatccaaga
     1621 gattactggt aacaaggatg tcatcacgac gtctcgtttt cctgggacaa ctcttgacaa
     1681 aattgaaatt cctttggatg atgggacgtt catttttgat acaccaggaa ttattcatag
     1741 gcaccagatg gctcattatt tatcccctaa agagctaaaa atagtgagtc ctaagaagga
     1801 aatcaagcct aagacgtatc aattaaaccc agaacaaact ctctttttag gtggtttgtc
     1861 tcgctttgac tttatcaatg gggagcgtca agggtttaca gctttttttg acaatcaact
     1921 agaattacat cgtacaaaat tagctggagc agatgctttt tatgataagc atgttggaac
     1981 tttgttaact cccccaggta agaaagagtt gacagcattt cctaaattag ttcgtcatga
     2041 atttacaatt gatcagaaaa tggatattgt tttttctggt ctaggatgga ttcgtgttaa
     2101 tggtcaaaaa gactcaaaag cgatagttgc tgcatgggct cctgaagggg tcgctgtcat
     2161 tgttcgtaaa gcgattattt aaaaataaaa aagaagttgg aaaaaaatgc ttacaagtaa
     2221 acaaagagct ttcttaaaat ctgaggctca tagcttaaaa ccgattgtac aaattggcaa
     2281 aaatggatta aatgaccaca ttaagactag tattcgtcaa gctttggatg ctagagaatt
     2341 gataaaggtc actttgttgc aaaatactga tgaagatatt catgaagtag cagagatttt
     2401 agaagaagaa attgggtgtg atacggtttt gaaaattggt cgtatcttga ttctctataa
     2461 ggtttctgct aagaaagaaa accgcaagtt gtcccctaaa gttaaagcaa tctagtcctt
     2521 ttatttgtat aggggctggt cttatgagac gaggactatt gtcgcgagaa ttttggagaa
     2581 agtatggcat tagaattgtt gacgcctttt acgaaggtgg aattagagga agaaaaaaaa
     2641 gaaagcaacc gcaaacagat tgggatttta ggagggaatt ttaatcctat tcacaatgca
     2701 caccttgtgg ttgcagatca agttcgccag caattaggat tagatcaggt gctattgatg
     2761 cctgaatgta aaccaccgca tgtggatgcc aaagagacta ttgatgagaa acatcgtctt
     2821 cgcatgttgg aattggctat tgaagatgtt gaagggctag ctattgaaac ctgtgaactt
     2881 gaacgtcagg gaatcagcta tacctatgat acgatgcttt atttgactga gcagcatcct
     2941 gatgtcgatt attattttat catcggagct gatatggttg attatttgcc aaagtggcac
     3001 cgtattgatg aactggtcaa actcgttcaa tttgttgggg ttcaacgtcc aaaatataaa
     3061 gctggaacct cttacccagt catttgggta gatcttcctt tgatggatat ttcttctagt
     3121 atgattaggg attttattaa aaaaggtcgt cagcccaatt atctcttacc taagcgggtt
     3181 ttagactaca ttactcaaga aggtttgtat caatgacata tgaagattat cttccttata
     3241 gcaggaccga actgttagca aaaattgcag agcagatgag ccctaaacgg tttaaacatg
     3301 tacttggcgt ggaaaaggca gccttgtcct tggcagagtg ttatggttgt aacccagaca
     3361 aagcagggtt agcagctctt ttacatgatt atgccaagga gtgccctgac caggtctttt
     3421 tagacttaat tgacaagtac caattatctc cagaattagc taaatggaat aataatgtct
     3481 ggcatggtat ggttggtatt tataagattc aagaagacct agggctaaaa gacaaagata
     3541 tcttgcgagc tattgaaatt cacactgttg gtgctgctga gatgaccttg ctggataagg
     3601 tcttatacgt tgctgattat attgaagaag gtcgcatttt tcctttggtt gatgacgcta
     3661 gaaaaatcgc gaagctcgat ttgaatcagg ctgttgccta tgaaacagtg aacactgtcg
     3721 cttatttagc ctcaaaagcg cagcctattt tcccacaaac tctggatacc tataatgcgt
     3781 tttgcagcta tttaaaggaa tactaatgga taatgatatg aggaataaaa tgaaaaaaga
     3841 agaactctta aaaattgttg tggaagcaac tgatgaaaag cgtgctaaag atattttaat
     3901 cttggattta gaggggttaa ctagtttgac tgattatttt gtgattgcga gtgcaacaaa
     3961 tagtcgtcaa ttagaggcta ttgcggataa tattcgtgaa aaggtaaaag aggctggtgg
     4021 agatgctagc catgttgaag gtaatagcca agcaggctgg gtcttgcttg atttgaccga
     4081 tgtggtggta catctttttt tagaagacga gcgttaccac tataatcttg aaaaattgtg
     4141 gcatgaagcg cctgctgtgg ctctagatgc ctatttagct taatgttaca aagagacctt
     4201 gtcaatacga cagggttttt gaggatgata atggaacata attatgaaaa atttgcgtca
     4261 gtttatgatg ctgtgatgga tgattctcta tatgacttgt ggacagattt ttcacttcga
     4321 catttaccaa agtctaaggg tcgaaatcgt ttgttagagt tggcctgtgg aaccggtatt
     4381 cagtcagttc gttttgctca agcaggtttt gatgtgactg gtttagactt aagtcaagac
     4441 atgctggcta ttgctaaaaa gcgtgcgcaa tctgctaaaa agaaaattga ttttattcaa
     4501 ggtaacatgc tggatttgtc acaggtgggg cagtttgatt ttgtaacctg ctattcggat
     4561 tccatttgct atatgcaaga cgaagttgat gttggcgatg tttttaaaga agtttatgat
     4621 gttttagcaa acgatggcat ctttattttt gatgtgcatt caacctatca aacggatgag
     4681 tgtttccctg gttattccta tcatgagaat gcagatgatt ttgcaatggt ttgggatacc
     4741 tatgctgacg aggctcctca ctctgttgtt cacgaactca ctttctttat ccaagaagac
     4801 gatggacgtt tttctcgctt tgatgaagtg catgaggaac gaacgtatga gttattgact
     4861 tatgatattt tgttggaaca agcagggttc aagtcattta aggtctatgc tgattttgaa
     4921 gataaggagc caactaagac cagcaagcgt tggttttttg tagcatataa atagaagaaa
     4981 aaagtagcct ttttagctat aggatttaat gaattatctt gaatgttact tatatgaaaa
     5041 gagttcatta ggcactaaat gctattatca aagcttagaa gtattggaga cattacgatt
     5101 gacactatgt ctgaaggttg ctaccaactt taaagaaagc attttctatt atacgttgtg
     5161 cttaagcatt tgatttaact cttattagcc ctataaaaga ttatttagta caatttgagg
     5221 agattctatg actgttaccg gaattatagc tgagtttaat ccgtttcaca atggacacaa
     5281 atatttgcta gaaacagcag agggactaaa aattattgct atgtcaggaa attttatgca
     5341 aagaggagag cctgctctta ttgataaatg gattcgatca gagatggctc ttaaaaatgg
     5401 tgcggatatt gttgtggaat tgcccttttt catttcagtt caatcagcag actattttgc
     5461 tcaaggagct attgatattc tttgtcaatt aggaattcag caattagcat ttgggacaga
     5521 gaatgtgatt gattatcaaa aactgattaa ggtctatgag aaaaaatcaa agcaaatgac
     5581 tgcctattta tcgacgcttg aagatacact tagctatcca caaaaaacac aaaaaatgtg
     5641 ggaaatcttt gctggagtta aattttcagg gcaaacgcca aatcatattt tggggttaag
     5701 ttacgcaaag gctagcgctg gaaagcatat acaactatgt cctatcaagc gtcaaggggc
     5761 tgcctaccat tcgaaagaca aaaatcatct gctagcttct gcaagtgcca ttagacagca
     5821 cctgaatgat tgggatttca taagtcattc agtaccaaat gcaggtttac ttataaacaa
     5881 tccccatatg tcatgggacc attatttttc attcttaaaa tatcaaattt tgaatcattc
     5941 tgatttaact agtatttttc aggtcaatga tgaattggcg agtcgtatta aaaaagcgat
     6001 aaaagttagt caaaatattg accacctagt tgacactgtt gctaccaaac gctatacaaa
     6061 agctcgtgta agacgtattt taacctacat tttggttaat gctaaggaac ctactttacc
     6121 taaggggatt catattctag ggtttacctc aaaaggacaa gcacatttaa aaaaattaaa
     6181 aaaaagcagg cctctgatta ctagaattgg agcagaaact tgggatgaga tgacacaaaa
     6241 agcagacagc atctatcaac ttgggcatca ggatatccca gaacaaagtt ttggaagaat
     6301 acctattata ataaaaaatg agaggctcaa ttaaactcta attgagtttt tttgggggct
     6361 tgactctaac attacgttga tggtttatac ttcagttaat ccaatgagga aattttataa
     6421 caataattaa aaaagtcagt caaaagatat gctttcgaag aacaggctaa cgtttttaca
     6481 agattatatc agtaatcatt ttgacaattg tagtaatgga atgttgccaa aatttagaat
     6541 gttgtgtgtt atgaatgaca agattttaaa ggaatactaa ttaaacggga ggtcgtgaac
     6601 cggaagctgt tgtcactcaa gcaccaaaat ctgtctgtaa cataatattg atgtatgaga
     6661 acgcaattat ttggttttta ttgtgatgct taaaacgatt ttatatttct attttaccaa
     6721 agcttttcaa agtgctataa taagggagtt agagtcaata ttagtaacgt taatgttgac
     6781 aatattcaat aaaatactat taaaaggaga caaaaatggg acgtaaatgg gcaaatattg
     6841 ttgctaaaaa aactgctaaa gatggagcaa catcaaaggt ctatgccaaa tttggtgttg
     6901 aaatttatgt ggctgccaaa caaggcgagc cagatccaga gttaaataca gctcttaaat
     6961 ttgtcattga tcgtgcaaag caagcacaag tgccaaagca tgttattgat aaagcgattg
     7021 ataaagctaa aggaaacaca gatgaaactt ttgtagaggg acgctatgaa ggttttggtc
     7081 caaatggttc aatgattatt gtggatactt tgacatcaaa tgttaaccgt acagcggcaa
     7141 atgtacgtac ggcttacggt aagaacggtg gcaatatggg agcttcagga tctgtatcct
     7201 acttatttga taaaaaaggg gtcatcgttt ttgctggtga tgatgctgac agtgtctttg
     7261 agcaattact tgaagcggat gtagacgtag atgatgttga agcagaagag ggaacaataa
     7321 cagtttatac cgccccaaca gatcttcata aaggtatcca agcacttcgc gataatggtg
     7381 tagaagaatt ccaagttact gaacttgaaa tgattcctca atcagaagta gtattggaag
     7441 gtgatgacct tgaaactttt gaaaagctta ttgatgcact cgaatcagat gatgatgttc
     7501 aaaaagtgta tcataatgta gcagattttt aaattgacat agaataataa aaagagttga
     7561 aatctatttc agctcttttt aagtgatgct tttataagta agtaccaggt aacatagtcg
     7621 ttgttagaag ataatgaaca atagtaaatc agtatcaact tgataggaat caattattag
     7681 tgaactctaa ttaaaaatgg taaactagac acaagaacaa aaaggagaga taggatgatt
     7741 aaaaaacaat atttaggaag agcaacaatt gccctagcat caacccttgt gctagcagct
     7801 tgtgggtcat caaaaacagc tgagtcagga aatcagggga gttctaaaga agtcttattt
     7861 gcaacggttg gaacaacagc tcccttttct tatgaaaaag gtggtcaact aactgggtac
     7921 gatatcgagg tggctaaagc agtctttaaa ggatcggatg attacaaggt gtcctttaaa
     7981 aaaacagaat ggtcttctat ctttacaggt ttggactcag gaaaatacca aatgggtggt
     8041 aacaacattt cctttaccaa agagcgttca gctaagtacc ttttttctta tccaatcgga
     8101 tcaacacctt ctgttttagt tgttccaaaa gacagtgata tcaagagctt tgatgatatc
     8161 caagggcata cgacacaagt tgttcaaggg actacaagtg ttgcacaatt agaagacttt
     8221 aataagaaac acagtgacaa cccggttact ctaaaattca ccaatgagaa cattactcaa
     8281 atgttaacca atttgagtga aggcaaggca gatttcaaga tttttgacgc tccaacggtt
     8341 aacgccatta ttaaaaatca agggttagat aatctcaaaa ccattgaact cacctcaaca
     8401 gagcaaccat ttatttattt tatctttagt caagatcaag agaaattgca aagctttgtt
     8461 aacaagcgta ttaaagagtt gactgctgac ggaactctta gcaagcttgc caaagagcac
     8521 cttggcggtg attacgtgcc atcagataaa gagttgaaac ttcctacagc taactaaacc
     8581 atctattaac cagttattca tctagaagac tggtttttct gatcggaaac aatattatag
     8641 tttatgaggt tatgttataa aaattgcaaa tagccttaat caaaatgaga tgttaaagtg
     8701 ctttttgaga agtgaatatt gtaagaagta tgctttgggt tttagtcctc aaataccaag
     8761 ttttttgttg actaaacaaa taaggatggt tagtatagca tatagtttaa aactatggta
     8821 tatgctagcc attatcaatt tgaaaactat atctaattaa gatacaataa tgatcgtaaa
     8881 caaaatgaat cgaggataac gctatgtctt ttaaaaaatg gattggaata gtcggaatcg
     8941 ctttagcatc aactgtattg gttgcttgtt ctgaaaaaca agatgataaa aacactctaa
     9001 ctattggggt gatgacaaaa acagaatctg atcaagcgag atgggataaa gttgaagaat
     9061 tattgaaaaa agacaatatc actttgaagt acaaagaatt tacagattac tcgcaaccta
     9121 ataaggcagt tgctaatggt gaagtcgata ttaatgcctt ccaacactat aatttcttaa
     9181 ataactggaa taaggaaaat aaggaacatt tggtggccat tgctgatacc tatatcagcc
     9241 caattaacct tttctctgga accagtcaag atgggaagac taaatacaaa tcagtagctg
     9301 atctgccaaa tggtgctcaa attgcagtac caaatgatgc gaccaatgaa agccgtgccc
     9361 tctatgtgct gcaatcagct ggcctcatta aattgaatgt gtctggtgat caattagcaa
     9421 ccattgccaa tatctcagag aacaaaaaga aattagatat caaggaatta gatgctagcc
     9481 aaacggcacg tgctttagta tctgctgatg cagctgttgt caataatagt tacgctgttc
     9541 ctgcaaaaat tgactacaaa acctctcttt tcaaagaaaa agcagatgac aattcaaaac
     9601 agtggattaa cattattgca ggtcaaaaag attgggaaaa atcagagaag gctgatgcta
     9661 ttaaaaaact catcaaggcc taccaaactg atgaggtgaa gaaagtcgtg gaaaaaactt
     9721 caaatggtat agatgtatcc gtatggtaaa ttttagccat tgttataaca agagtgtggt
     9781 cgtgtttaaa acacatgctt tcttgcatgc ttgaggaaga gtttacgact aatttacctt
     9841 tagaaagcta tttaagacct tttccctttt aggatttaga aaccttggga agactattgc
     9901 atgttatctt aatagtcatg attatgcagg cgatgaaaac attgctatcg tagattactg
     9961 tcgccatatc gtactaatag aggagttatt aaaatcttat gaatgaagca ataattcaat
    10021 tagatcatat tgatattacc ttccgtcaaa aaaaacgggt tatcgaagct gttaaagatg
    10081 tcacggttca tatcaatcaa ggagatattt atggcattgt tgggtattca ggtgccggga
    10141 aatcaactct tgtgcgtgtg attaacctgc tacaggcacc aacaaacggg aaaatcactg
    10201 ttgatgggga tgtgaccttt gaccagggga aaattcaatt gtcagccaat gcccttcgtc
    10261 aaaaacgacg tgatattggc atgatcttcc aacatttcaa tttgatggcc caaaaaacag
    10321 ccaaagaaaa tgtagcattt gcgctccgcc attcatcgtt aagtaagact gagaaagaac
    10381 ataaagttat cgagctgcta gaacttgtag gtttatcaga gcgagcagat aactaccctg
    10441 cccagttatc gggtgggcaa aaacaaaggg tggctattgc gcgtgctcta gctaacgatc
    10501 caaaaatttt gatttcagat gaggcaacat cagcactaga tccaaaaacc actaaacaaa
    10561 ttttggcgct cttgcaagaa ttaaaccgca aacttggcct taccattgtt atgattactc
    10621 atgaaatgca aattgttaag gatatttgta atcgtgttgc tgttatgcaa aatggtgttt
    10681 tgattgaaga aggttctgtc cttgatatct tttcaaatcc aaaagaagcc ttgacacaga
    10741 aatttatcac aacagctaca gggattgatg aggctttaga aaaaattaac caacaagaca
    10801 ttgtcaaaca tttgcctgca aatgcccttc tagctcagtt gaaatatgca ggaacttcta
    10861 cggatgagcc tctacttaat agcatttacc gtcagtttga agtgacagct aatattttgt
    10921 atggcaatat tgagatttta gatcatattc cagttggtga catgattgtt gtcttggaag
    10981 ggcaagctga aaatattctt gcggctgaga aagccttgca tgaagctggt gttgatgtta
    11041 gtattttaaa gagaggagcc tagatgtcac agttaattca aacttatttg ccaaatgttt
    11101 atgaactcgg atggtctgga gatgctggtt ggggcttagc gatttggaat actttataca
    11161 tgaccattgt gccttttatt gttgggggtg ctattggtct cttattaggc ttgttattag
    11221 ttttaacagg accggacggt gttattgaaa acaaaacgat ttgttgggtc attgataaag
    11281 ttacctctat ttttagagcc attccttttg ttattttgat tgctatttta gctagcttta
    11341 cctatttgct tttaagaaca actttagggg caacagcggc cttggtacct ttaacctttg
    11401 cgacttttcc tttttatgcc cgtcaggtcc aagttgtttt ttcagaatta gacaagggtg
    11461 ttattgaagc agcgcaagct tcaggtgcta ctttctggga tattgtcaaa gtgtatctta
    11521 gtgaaggttt accagatctt attcgtgttt ctacagtcac cttaatttct ttagttgggg
    11581 aaactgccat ggcaggagct atcggtgctg gaggattagg aaatgtagcg atttcttatg
    11641 gttataatcg ttttaacaat gatgtgactt gggtagcgac tattattatt cttttaatta
    11701 tttttgctat ccaatttatt ggtgatagct tgactagaag gtttagtcat aaataaacga
    11761 aacaacaccc taagttttta cttagggtgt tgttgtttag atgatgtcat tagcttttct
    11821 tcgttttact tagtataagc cctattaaaa aaccaatagc agcaaagata atccatccca
    11881 ttgagaattg ccctagtgga acagtttttt ggaaaaaagt tacaacggct tctggtaaat
    11941 gaaataatcc agtcatttgt gatagtgtta ggagtgcatc aaatatggca ggaataaagg
    12001 ttagaccaat tgtagttcga tagacaatag gatcattatt gaagcatttt tgtgccaaaa
    12061 caaggaaaat taaatcaact gttaatgggt ataaaaggaa taaaacagga gctgaccagt
    12121 tgataataac tgataaacca ccaaaataaa agaaagctga tagtaaagta aagatagttg
    12181 cccaagcaat atgagataaa gcaggcacta atttatggaa gtattcagca cttgacgtga
    12241 ttaagcctgt tgaagtggtt agacaggcca ggaaaatcac aacagctaga aatgcttgtc
    12301 cgatgccacc taggtaaaaa cgagaagcat gacttaagat ttgaccgcca ttaactggat
    12361 taccatgaag ggtaaagctg ccatcactaa aaggaaataa tgattgtgat gttgctccaa
    12421 tacgaccgac aaagatatag acaagtgcta atagcaaaat ggcaatagcc ccagaaataa
    12481 gtgttatttt ggtcacttct ttgtccgtct tagcgccaaa ttgtttggta gcctcaatga
    12541 ctaaaatagc aaaaacaaga gaagctagtg catccatagt gccataacct tgaattaatc
    12601 ctgctataaa aggaaaatct ttaaaggcat tattaacacc gaccccagcg ttaaaagcat
    12661 caccgtaatt tccagcagga tggacaaagg acgcgataac caaaatagaa ataacaacta
    12721 acaacgttgg cgttaaaaat tttccgatat tttcagctag cttactaggt ttgatagcaa
    12781 ggaagtagga cagaccaaaa aatagtatag cataaatagc tttattggtt gtattatctc
    12841 ctaagatagg agcgataccg actgaaaaag aagtggctcc tgttcttgga atagcaaaaa
    12901 atgggccaat agataaatac aaaatggaag aatagaagat tgcataccat ttagagatgg
    12961 ggcgtgccaa actttcaaca tcgcctgatc cagatttagc aacagcaatg acaccgagta
    13021 aaggcaagga gacaccagtt aaacaaaaac caatgataga ccatagaatc tgatgacctg
    13081 agtagatgcc taaaaaagct gggtaaatga ggtttgctgc tccaaaaaat agcgcaaata
    13141 gcatgaatcc aatgacgata tatacatttt tttgtttcat ttataaatag tctttctatt
    13201 gatactaatt cgaagattct aacaatttta attatattat gtgtcaaaa
//
LOCUS       DAUGOH010000043        13088 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUGOH010000043 DAUGOH010000000
VERSION     DAUGOH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13088
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.043"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            126..551
                     /gene="rplK"
                     /locus_tag="VH957_001426"
     CDS             126..551
                     /gene="rplK"
                     /locus_tag="VH957_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEQ8559326.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            657..1346
                     /gene="rplA"
                     /locus_tag="VH957_001427"
     CDS             657..1346
                     /gene="rplA"
                     /locus_tag="VH957_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEQ8559327.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            1669..2397
                     /locus_tag="VH957_001428"
     CDS             1669..2397
                     /locus_tag="VH957_001428"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEQ8559328.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            2426..2983
                     /gene="frr"
                     /locus_tag="VH957_001429"
     CDS             2426..2983
                     /gene="frr"
                     /locus_tag="VH957_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEQ8559329.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            3092..3949
                     /locus_tag="VH957_001430"
     CDS             3092..3949
                     /locus_tag="VH957_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8559330.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            4022..4531
                     /gene="msrA"
                     /locus_tag="VH957_001431"
     CDS             4022..4531
                     /gene="msrA"
                     /locus_tag="VH957_001431"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEQ8559331.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            4528..4743
                     /locus_tag="VH957_001432"
     CDS             4528..4743
                     /locus_tag="VH957_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEQ8559332.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            4899..6068
                     /locus_tag="VH957_001433"
     CDS             4899..6068
                     /locus_tag="VH957_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8559333.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQVSATSQSTVPMAPSATPSDVPTTPFASAKPDSSVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDSTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMN
                     AGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYA
                     IDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            6382..8154
                     /locus_tag="VH957_001434"
     CDS             6382..8154
                     /locus_tag="VH957_001434"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEQ8559334.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWIYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEGKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKDNETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            8313..9365
                     /locus_tag="VH957_001435"
     CDS             8313..9365
                     /locus_tag="VH957_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEQ8559335.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            9411..9986
                     /locus_tag="VH957_001436"
     CDS             9411..9986
                     /locus_tag="VH957_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEQ8559336.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            10145..10642
                     /gene="ybeY"
                     /locus_tag="VH957_001437"
     CDS             10145..10642
                     /gene="ybeY"
                     /locus_tag="VH957_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEQ8559337.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            10623..11030
                     /locus_tag="VH957_001438"
     CDS             10623..11030
                     /locus_tag="VH957_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEQ8559338.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            11150..12046
                     /gene="era"
                     /locus_tag="VH957_001439"
     CDS             11150..12046
                     /gene="era"
                     /locus_tag="VH957_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEQ8559339.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            12067..12543
                     /locus_tag="VH957_001440"
     CDS             12067..12543
                     /locus_tag="VH957_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8559340.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            complement(12849..13028)
                     /locus_tag="VH957_001441"
     CDS             complement(12849..13028)
                     /locus_tag="VH957_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559341.1"
                     /translation="MRYPHAHIILIGNHINYEEIFKNHYRVFGVIDTTSHKSLKSIRD
                     QIQLYLDELYNSNNG"
BASE COUNT         4086 a         2398 c         2837 g         3767 t
ORIGIN      
        1 tattttaaca aaaagacttg atttattttg gcaataagct ataatagtaa ggtatgcaat
       61 attgcatatc tgtgggaggt aaaaatctca attaccgcca aaaccacaac aggaggattt
      121 ttaaaatggc taaaaaagtc gaaaaacttg taaaacttca aatccctgct ggtaaagcta
      181 caccagctcc accagttgga ccagctcttg gtcaagcagg tatcaacatc atgggcttca
      241 ctaaagaatt taacgctcgt acagctgatc aagctggtat gatcatccca gttgttatct
      301 cagtttatga agacaaatca tttgatttca tcactaaaac accaccagct gctgttcttt
      361 tgaaaaaagc tgcaggtgtt gaaaaaggat caggtacacc taacactact aaggttgcga
      421 cagttactcg tgcacaagta caagaaattg ctgaaactaa gatgccagat ttgaacgctg
      481 caaacattga agctgcaatg cgtatgatcg aaggtactgc tcgttctatg ggattcactg
      541 ttactgacta gtcagtcaag aacccctatt acccgcacga cttcatcata agagatgagt
      601 gacgtgggag attttaaatc aaatcgatat gaccacatta caaggagaat tttaaaatgg
      661 ctaaaaaaag caaacaaatg cgtgctgcac ttgaaaaagt agatagcaca aaagcgtaca
      721 gtgtagaaga agctgtagca ttagtaaaag aaacgaactt cgcaaaattt gatgcgtctg
      781 ttgaagttgc ttacaacttg aacattgacg ttcgtaaagc agaccaacaa atccgtggcg
      841 caatggtatt gccaaacgga actggtaaaa cacaacgtgt tcttgttttt gcacgtggtg
      901 caaaagctga agaagcaaaa gcagctggtg cagacttcgt aggtgaagac gaccttgttg
      961 caaaaatcaa tggtggatgg cttgactttg acgttgttat cgcaacgcca gacatgatgg
     1021 ctatcgtagg tcgtcttgga cgtgtccttg gacctcgtaa cttgatgcca aaccctaaaa
     1081 ctggtacagt aacgatggat gttgctaaag ccgttgaaga gtctaaaggt ggtaaaatca
     1141 cttaccgtgc tgacaaagca ggtaatgttc aagctcttat tggtaaagtt tcatttgatg
     1201 ctgacaaatt ggttgaaaac ttcaaagcct tccacgatgt aatggctaaa gctaagcctg
     1261 caacagctaa aggaacttac atggcaaacg tctcaatcac atcaacacaa ggtgttggta
     1321 tcaaggttga tcctaactca ctttaagaaa aaaattaggg catcgcctaa tcatagcaaa
     1381 aagacaaatt tctgaagaca aatcttcact agaggtttgt cttttttatg gtttaaaatg
     1441 gaatgcaaac aaaaaagtgt aggcgataat accatgaaag gagttgattc tcttaatgag
     1501 atgtggtgtt aacacatcat gagctcacaa aaaatgataa aggaagtatc ggtggtgtta
     1561 aaaaaaggga ttttaattga tatttattag cctctaaaat gtcctttccc tattcataat
     1621 tgagggtttg tggtaaaata gtaaggacaa actaaggaga acatagtagt ggaacctaaa
     1681 tatcaacgta tattaattaa gttatctggt gaagcattag cgggtgaaaa aggagttggc
     1741 attgacattc caactgttca ggctattgca aaagaaattg ccgaagttca tgtgtcggga
     1801 gtacagatcg ctcttgttat tggtggaggc aatctctggc gtggagagcc tgcagcagac
     1861 gctggaatgg accgtgttca ggctgattac actggcatgc ttggaacggt gatgaatgcc
     1921 ctagtcatgg ctgatagtct tcaacattat ggtgttgata cccgtgtgca aacagctatt
     1981 cctatgcaaa atgtagcaga accttatatt cgcggacgtg ccttgcgcca tctagaaaaa
     2041 aatcggattg ttgtttttgg agctggtatt ggctcgcctt atttttcaac agacaccacc
     2101 gcggcactgc gtgctgctga gattgaagca gatgctattt taatggcaaa aaatggtgtg
     2161 gatggggtct ataatgctga tcctaaaaaa gatgctaatg cggttaaatt tgatgaatta
     2221 acacatggtg aagtgatcaa acgtggtctc aaaatcatgg atgcaacggc atcgacctta
     2281 tcgatggata acgatattga tttggtggtt ttcaatatga atgaagctgg caatattcaa
     2341 cgtgttgtct ttggagaaca tattggaact actgtatcaa ataaagtttg tgactaaaag
     2401 ttagaaaaga aagagagtaa ttatcatggc aaatgcaatt attgaaactg caaaagaacg
     2461 ttttgcacaa tcccatcagt ctttatcacg tgaatatgcc agcattcgtg cgggtcgtgc
     2521 caacgctagt cttttagacc gtatccaagt tgattattac ggggcaccga cgccattaaa
     2581 tcaattggct tcaatcactg tgccagaagc gcgtgtctta ttgatctcgc cttttgataa
     2641 atcttctatc aaagatatcg agcgcgctct taacgcatca gatttaggca ttacacctgc
     2701 taacgatggc tctgtcattc gtttggttat tccagctttg accgaagaaa cacgtaaaga
     2761 attagccaaa gaagtgaaaa aagttggtga aaatgctaaa attgcaatcc gtaatatccg
     2821 ccgtgatgct atggatgatg ctaaaaagca agaaaaagca aaagaaatca ctgaagatga
     2881 gttaaaaaca cttgagaaag atatccaaaa agcaaccgat gatgctatca aagaaattga
     2941 ccgcatgacg gctgaaaaag aaaaagaatt gctctcagtg taacaggatt tctacgaaaa
     3001 atagacgact atagacacaa aaagataggt gaccatttca gaagcgtttg gttttgattt
     3061 gtccctattt ttttaaagaa agaaaaaaga tatgaatgat ttactagcaa cagtcattac
     3121 tgggcttatt aaagaagaaa acgctaatga ctattttatc caaaaagagg ggtttacctt
     3181 taccttgtct aaagcagaag gagaacgcca gattggtgat atggtcacag gctttgccta
     3241 tacagacata aagcaaaagg cacgtctcac aaccaaagag atccgttcaa cacggacaag
     3301 ttatggctgg ggggaagtga cagaggttcg tcgtgaccta ggcgtttttg tcgatacagg
     3361 aattccaaat aaagaaattg tggtttcttt ggacgtgttg cctgaaatga aagaactatg
     3421 gcctaaaaaa ggggataaac tttacattcg tttggatgtg gataaaaaag accgtatttg
     3481 gggacttcca gcagagcctg aggtctttca aaagatggct agccctgcat acaataatat
     3541 gcaaaatcaa cattggccag caattgttta ccgcctaaaa ttaacaggaa cgtttgttta
     3601 cctgcctgaa aacaacatgt taggctttat tcacccaagt gaacgctacg cagaaccgcg
     3661 cttaggtcag gttttagatg cccgtgtgat tgggtttaga gaggtcgatc gtaccctaaa
     3721 cttgtcgttg aaaccacgtt cttttgagat gttggagaat gacgctcaga tgattgtcac
     3781 ctatcttgaa gccaatggtg gtttcatgac cttaaatgac aaatcaagtc cagaagagat
     3841 taaagcaacc tttggtattt caaaaggcca gtttaaaaaa gccttgggtg gattgatgaa
     3901 agctaaacgc atcaaacaag acgccacagg aactgaatta ataggataaa aatgctttgc
     3961 cactggcaaa gttttttgtt acaatgaaga ccattaactg aagaaaaagg ggatatagag
     4021 aatggaaaga gccatttttg caggaggttg tttctggtgt atggtgcaac cttttgagga
     4081 gcaagcaggt attttgtcag tcagaagtgg ctacacaggt gggcatctcc caaatcctag
     4141 ctatgaacaa gtttgtgcca aaacaacagg acatacagaa gctgttgaaa ttatttttga
     4201 ccctaagcaa atcgcttata aagatttggt agagctctat tgggcgcaga cggatccaac
     4261 agacgccttt gggcaatttg aagatcgtgg ggacaactac cgtcctgtca tttactatac
     4321 aacggaaaga caaaaagaaa ttgcagagca atcaaaagca aacttgcaag cttcaggacg
     4381 ttttgaccaa cccattgtca ccactattga accagcagag ccattttatc tcgcagagga
     4441 ttatcaccaa ggattttata aaaagaatcc caagcggtat gcacaaagca gtgctattcg
     4501 tcatcagttt ttagaggaga attggtcatg agaaaatcat tttacagctg gctgatgaca
     4561 caacgtaacc ctaaatcaaa tgaacctgtg gcgattttag cagatttggt gtttgatgac
     4621 accacttttc caaagcatac caatgatttt gaactcatta gtcggtatct agaagatcaa
     4681 gctagttttt cctttaattt aggtcaattt gatgaaatct gggaagatta tctagcacat
     4741 taatacgtgg ataaaaaaga gtcatatcga ctcttttgaa gggttatcac gttattatta
     4801 caaaatgaca tcactttctt tcaaaaaaat gacaagctac tttttttctt aaaaatatgc
     4861 tatgatatag cttagaaaaa aataaaaagg aagcagagat gattattact aaaaagagct
     4921 tatttgtgac aagtgtcgct ttgtcgttag cacctttggc gacagcacag gcacaagagt
     4981 ggacaccacg atcggttaca gaaatcaagt ctgaactcgt cctagttgat aatgttttta
     5041 cttatactgt aaaatacggt gacactttaa gcacaattgc tgaagcaatg ggaattgatg
     5101 tgcatgtctt aggagatatt aatcatattg ctaatattga cttaattttt ccagacacga
     5161 tcctaacagc caactacaac caacacggtc aggcaacgac tttgacggtt caagcgcctg
     5221 cttctagtcc agctagcgtt agtcatgtac ctagcagtga gccattaccc caagtatctg
     5281 ccacctctca atcgactgtt cctatggcac catctgcgac accatctgat gtcccaacga
     5341 caccattcgc atctgcaaag ccagatagtt ctgtgacagc gtcatctgag ctcacatcgt
     5401 caacgaatga tgtttcgact gagttgtcta gcgaatcaca aaagcagcca gaagtaccac
     5461 aagaagcagt tccaactcct aaagcagctg aaacgactga agtcgaacct aagacagaca
     5521 tctcagaaga ttcaacttca gctaataggc ctgtacctaa cgagagtgct tcagaagaag
     5581 tttcttctgc ggccccagca caagccccag cagaaaaaga agaaacctct gcgccagcag
     5641 cacaaaaagc tgtagctgac accacaagtg ttgcaacctc aaatggcctt tcttacgctc
     5701 caaaccatgc ctacaatcca atgaatgcag ggcttcaacc acaaacagca gccttcaaag
     5761 aagaagtggc ttctgccttt ggtattacgt catttagtgg ttaccgtcca ggtgatccag
     5821 gagatcatgg taaaggtttg gccattgatt ttatggtgcc tgaaaattct gctcttggtg
     5881 atcaagttgc tcaatatgcc attgaccata tggcagagcg tggtatttca tacgttattt
     5941 ggaaacagcg attctatgcg ccatttgcaa gtatttacgg accagcctac acatggaacc
     6001 ccatgccaga tcgcggcagt attacagaaa accattatga tcatgttcat gtctccttta
     6061 atgcttaatt catgctatca aaaaaactca cgtttaggcg tgagtttttt gacaattctg
     6121 acagagtaag ccctataaga ggctgagata cgcttttaat acctgttgtt tttctcaccc
     6181 tttagacagt tttaacgtta tgtctaaaag agatggtttt tattagcgca aatatgggtt
     6241 taggggtaaa ataaaggtaa ttaacctgat atgatcatga taaaggtaga agaataccta
     6301 ttatttcgtg acaactgagc aatctgcctt acctttggag tgatgatatc actttgcttg
     6361 actattcaag gaggtcttga aatgtattat actagtggta attacgaagc ttttgcaaca
     6421 cctcgaaaac ctgaaggggt agatcagaaa tcagcttata ttgttggtac tggtttagct
     6481 ggtttagcag cagctgtttt ccttattcgc gatgggcata tggctgggga acgcattcat
     6541 ctgtttgagg aattgccttt agcaggtggt tctttagatg gtattgaaaa gcctcatctt
     6601 ggttttgtga cccgtggtgg tcgtgagatg gaaaatcatt ttgagtgtat gtgggacatg
     6661 tatcggtcta ttccctcact ggaaattcct ggtgcgtctt atttggatga attttattgg
     6721 ttggataagg atgatcctaa ctcatccaac tgtcgtttga ttcacaagag aggaaatcgt
     6781 gtggatgatg acggccagta tacgctcggt aaacagtcaa aagaattaat ccatttaatc
     6841 atgaagacag aagaatctct aggagatcaa accattgaag agttcttctc agaagatttc
     6901 tttaagagta atttttggat ctattgggca accatgtttg cttttgaaaa atggcattct
     6961 gctgtagaaa tgcggcgcta tgcgatgagg tttatccacc atattgatgg tttgccagat
     7021 ttcacctctc tcaagttcaa caaatataac caatatgatt ctatggtcaa accgattatt
     7081 gcttacctag aatcacacga cgttgacatc caatttgaca caaaagtcac tgatattcag
     7141 gtagaacaaa cagctggtaa aaaggtagca aaaaccatcc atatgacggt gtctggggag
     7201 ggtaaggcga ttgagctaac acctgatgat ttggtttttg tgaccaatgg ttctattact
     7261 gaaagtagca catacggtag tcatcacgaa gtggctaagc caaccaaagc gttaggtggt
     7321 tcttggaatt tatgggaaaa tctagctgct caatcagatg attttggtca tcctaaagtg
     7381 ttttaccagg acttgcctgc tgaaagctgg tttgtgtctg ccacagcaac cataaaacac
     7441 ccagctatcg agccttatat tgaacgtttg acccaccgtg atttgcacga tggcaaagtg
     7501 aacactggcg gcatcatcac tattacagat tccaactgga tgatgagctt tgctattcac
     7561 cgtcaacctc attttaaaga acaaaaagat aatgaaacca ctgtctggat ttacggtctt
     7621 tattccaata gtgagggcaa ttacgtccac aagaaaattg aggagtgtac aggtcaagaa
     7681 atcacagaag aatggttgta ccaccttggg gtacctgttg ataaaatcaa ggacttagcg
     7741 agtcaggact atatcaatac agttcctgtt tacatgcctt atattacgag ttactttatg
     7801 ccacgcgtca aaggagaccg tccgaaagtt atcccagatg gttcagtcaa cttggccttt
     7861 attggtaact ttgcggaatc tccatctcga gatacggtct ttacgactga gtattctatt
     7921 cgtactgcca tggaagcagt gtatagcttc ttgaatgtgg aacgaggcat tccagaagtc
     7981 tttaattcag cctatgatat tcgtgaattg ctcaaagcct tttattacct taatgataaa
     8041 aaggcaatca aggatatgga tttgccaatt cctgcactga ttgagaaaat cggacataaa
     8101 aaaatcaagg atacctttat cgaagaattg ctcaaagatg ctaatcttat gtaacatgct
     8161 ttagagtagt taaagctgat aagtttaggc ttatcagctt ttttgatgat ttatagaaaa
     8221 gtgataaagg aaaagtctga cgtgaacgtc acataagaat ttaaaatttg ttataatgta
     8281 agcaataaag atgaaagaaa gagggactct atttgcaaga gtattctatt gacattacct
     8341 taacccatcc tgatgatgtt ttagctcttt ttggtagcaa cgagcgtcat ttgaagctaa
     8401 tagaagctca tttaggagtt attgttcacg caagaaccga gcgagtccaa gtgattggtg
     8461 atgatgaaga agctgtggaa ttggctcgat tgaccatcaa agccctactg gttctagtgg
     8521 gtcgtggcat ggtggtcaac acatcagatg tggtgacagc tttatctatg gcagaatctc
     8581 atcagattga ccaatttatg gcgctttatg aagaagaaat cattaaagat aactatggta
     8641 aggcaatacg agtcaaaaca ttaggtcaaa aaacctatgt tgatagtgtc aaacgtcatg
     8701 atgtggtttt tggtgtagga cctgcaggga cagggaaaac cttcttagct gttacgcttg
     8761 cagtcactgc tctgaaaaga ggacaggtaa agcgtattat tttgacgcgt cctgcggtag
     8821 aagctggtga aagcctaggt tttttaccag gcgatttgaa agaaaaggtg gatccttacc
     8881 tcagaccggt ttacgatgcc ctttatcaca ttttaggcaa ggaacaaacc acacgcctga
     8941 tggaacgaga tgtgattgag attgctccgt tagcttatat gcggggtcgt actctggatg
     9001 acgcttttgt tatcttagat gaggctcaaa acacgactat catgcaaatg aagatgtttt
     9061 tgacccgtct tggttttaat tctaaaatga ttgtcaatgg agatacgagt cagattgacc
     9121 tccctcgaaa tgtcaagtct ggtttgattg atgctactca gaaattacaa ggcattaaac
     9181 agattgattt tgtctatttc tctgctaaag atgttgtccg acatcctgtt gtggctgata
     9241 ttatcaaggc ttatgaaacg tcctcagagg agatgaagga cttactaaaa cctaaggcta
     9301 gtgacgttga agctgactac cagccaggct tgacaaaata ccctgtgatc ggtcaagagc
     9361 actaagacct ttacgatgat gtttaatatg gcctttttaa ggaggattct atggatgatt
     9421 taaccaaagc tattatggca gatgaggcta atctctccta taccgaaaga ggtatttttc
     9481 ctttatatga tgctcctcaa acagctagga ttattattgt tggccaagct cctggaatag
     9541 tagctcaaga aaccaaactt tactggaatg atcgtagtgg catccgctta cgagactggc
     9601 taggtgtgga caatgacacc ttttaccact caggattgtt tggcattatc cctatggatt
     9661 tctattatcc tggtaaggga aaatccggtg acttaccacc tagagaaggt tttgcggcta
     9721 agtggcaccc gccattaaga gcattgatgc cagaagttga attgacgatt ttggttggtc
     9781 gctatgctca ggacttttac cttggtaaca aggcttacaa aaccttaact gaaacagtcc
     9841 gtcactttga ggattacttg ccagactatt ttccacttgt tcatccttct ccaagaaacc
     9901 aattgtggtt agctaagaac ccctggtttg agcaggattt attacctatc ttgcaaaaac
     9961 gtgtggaggc aattctaacc aaataggccc tgatttacct agcattccca tttttaaggg
    10021 gcttgtggta taatgggtaa ataacaaatg ctgattgaaa ggataaggga aattatctgt
    10081 cagataataa tgggtgccca acataccaaa tgaggtgggc agcccttccc taacaattaa
    10141 ccttatgtat atcgagatga ttgacgaaac gggacaagtt tcgcaagaga ttatggagca
    10201 aacacttgat ttgctcaatt ttgctgctca aaagacgggc aaagaagaaa aagaaatgtc
    10261 tgtgaccttt gtgaccaatg aaagaagtca tgaactcaac ttagaatacc gagatactga
    10321 tcgtccaaca gatgtgattt ctctagaata taagccagaa acgcctattt tatttagtca
    10381 agaggatttg gctgctgatc ctagtttggc agagatgatg gcagagtttg atgcttatat
    10441 tggcgaattg tttatttcta ttgacaaggc gcgtgagcag tcccaagaat atgggcactc
    10501 ttttgagcgt gaaatgggat ttttagctgt tcatggattc ttacatatta atgggtatga
    10561 tcactacacc cttgaagaag aaaaagagat gtttacctta caggaagaga ttttgactgc
    10621 ttatggcctt acacgacaat aataccacca aacggaaatg gaaaaacaga accattacct
    10681 caagcctgga gtttgccttg acaggggttt tcacagcttt taaggaagaa cgcaatctca
    10741 gaagtcacct tttgtctgcc tgtttagctt gtgttgctgg tttatttttt agcatttcag
    10801 ccatcgaatg gttattttta cttctagcca tttttttggt cattacctta gaaattgtca
    10861 attctgctat tgaaaatgta gttgatttgg ctagtgacta tcacttttct atgctagcta
    10921 aaaatgctaa ggatatggca gcaggtgctg ttttgatgat ttctggctat gctgtcttga
    10981 caggacttat tatttttatt cctaaaattt ggaatatttt cgttcattaa aaagaaagga
    11041 atgggctatc ctatgtgatg atggcatagg agaataagga aaggacaaga cggttaagct
    11101 tagtgacaag cttgatctga agccctaccg ttaaagcccg taattatcta tgtttaaatc
    11161 aggctttgta gccattcttg gtcgtccaaa tgttggcaaa tccacctttt taaatcacgt
    11221 catggggcaa aaaattgcca tcatgagtga caaggctcag accacccgta ataaaattat
    11281 gggcatttac accacagaaa cagaacaaat tgtctttatt gatacgccag gtattcataa
    11341 accaaagacc gcccttggtg attttatggt tgaatctgct tatagtactt tacgtgaagt
    11401 tgagacggtt cttttcatgg ttcctgccga tgaaaagcgt ggtaagggtg acgacatgat
    11461 tatcgagcgg ctaaaagcag ctaagattcc cgttatttta gtcatcaaca aaattgataa
    11521 ggttcatcca gaccaacttt tggaacagat tgatgacttc cgtagccaaa tggattttaa
    11581 agaagtggtc ccaatttctg ccctagaagg taataatgtg ccaaccctaa tcaagttatt
    11641 aactgataat cttgaagaag gtttccaata ttttccagaa gatcagatta ctgatcatcc
    11701 agaacgtttc cttgtgtcag aaatggttcg tgagaaggta ctgcatttga cgcaacaaga
    11761 ggttccacat tccgtagctg ttgttgtcga atccatgaag cgagatgaag agactgataa
    11821 agtgcatatc cgtgcaacca ttatggtgga gcgcgatagc caaaaaggca tcatcattgg
    11881 aaaacaagga gccatgctca aaaaaatcgg aaaaatggcg cgccgtgata ttgaactcat
    11941 gctaggtgac aaggtctact tagaaacgtg ggtcaaagtc aagaaaaact ggcgggataa
    12001 aaagcttgac cttgctgact ttggttataa tgagaaagaa tactaacata gtaaagcgag
    12061 catcatatgc cacaagacta catttcttat atccgctcca aagttgggca tgataagatt
    12121 attcttaact ttgctggtgg gattttgacc aatgatgacg gcaaggtgct gatgcagttg
    12181 cgtggtgata agaaaacctg ggctattcct ggtggcacta tggaactggg tgagagctct
    12241 ttagagactt gcaaacgtga gttcttagag gaaaccggaa ttgaggttga agctgttcgc
    12301 ttactgaatg tttacactca ttttgaggaa gtttatccca acggtgatgc tgttcagact
    12361 attgtcttta tctatgaact aacggctgtt tctgatatgg ctattgataa ctttcataat
    12421 gaggaaacgc tcaagttaca gtttttctct catgaggaga tagcagagtt agagagtgtc
    12481 tcagccaaac atcgcctgat gttagaggaa tattttagtg atagctttgc tatggggcat
    12541 taagaactct ctaggacagt tggagtattt ttggagattg gcttgttaaa aaaatttttg
    12601 aaagacgatg tttcgagagc ttatgctctc tttttttgct tccaattttt ctgattaagt
    12661 ctgaataatt ttgttaaatg ttaacaggat tttctttcca attgatacta gcagacatca
    12721 aacatttgtt ttagagttat gacgaattgc cacctagcca tgcatgactt aggcaagttg
    12781 aacctaactg tggcaataga cttggaaggg gtgacaagaa tcatttccta aaagaattga
    12841 tgaagtgcct atccattatt cgaattgtaa agttcgtcta agtaaagttg aatttgatct
    12901 cgaatggact ttaatgattt atgacttgtt gtgtcaataa caccaaaaac tcgataatga
    12961 tttttaaata tttcctcgta attaatatga tttccgatta gaataatatg agcatgagga
    13021 taacgcatac gtatttcgtt tagaaggtca tatacttgct tagatttaaa aaagtatgat
    13081 ttatgata
//
LOCUS       DAUGOH010000044        13047 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUGOH010000044 DAUGOH010000000
VERSION     DAUGOH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13047
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.044"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..1262)
                     /locus_tag="VH957_001442"
     CDS             complement(<1..1262)
                     /locus_tag="VH957_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEQ8559342.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYYKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPYFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGK"
     gene            1352..2218
                     /locus_tag="VH957_001443"
     CDS             1352..2218
                     /locus_tag="VH957_001443"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEQ8559343.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQSPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLSLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLDYLTKSFKK
                     LLEEKNVISKIS"
     gene            2196..2753
                     /locus_tag="VH957_001444"
     CDS             2196..2753
                     /locus_tag="VH957_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8559344.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            2887..4431
                     /locus_tag="VH957_001445"
     CDS             2887..4431
                     /locus_tag="VH957_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8559345.1"
                     /translation="MSILEVKQLSYGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            4795..6018
                     /locus_tag="VH957_001446"
     CDS             4795..6018
                     /locus_tag="VH957_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8559346.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPKVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
     gene            complement(6060..7622)
                     /gene="guaA"
                     /locus_tag="VH957_001447"
     CDS             complement(6060..7622)
                     /gene="guaA"
                     /locus_tag="VH957_001447"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEQ8559347.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7789..9222
                     /locus_tag="VH957_001448"
     CDS             7789..9222
                     /locus_tag="VH957_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559348.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKEPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            9305..10003
                     /locus_tag="VH957_001449"
     CDS             9305..10003
                     /locus_tag="VH957_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8559349.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            10092..10433
                     /locus_tag="VH957_001450"
     CDS             10092..10433
                     /locus_tag="VH957_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEQ8559350.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            10448..12010
                     /gene="ffh"
                     /locus_tag="VH957_001451"
     CDS             10448..12010
                     /gene="ffh"
                     /locus_tag="VH957_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEQ8559351.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFTMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(12127..12825)
                     /locus_tag="VH957_001452"
     CDS             complement(12127..12825)
                     /locus_tag="VH957_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8559352.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
BASE COUNT         4307 a         2181 c         2494 g         4065 t
ORIGIN      
        1 ctctttccac aagtattttt gattagcgag tttaatttgc tttgtatttg ttgattgata
       61 gcaatagaga gatagcgctt ttttccagtt attattattc tatcagattt atctaatgta
      121 aagtttctat aagagtctga tgtcgtgtaa tcaatcacta aatgagtagg ggttagttga
      181 tagtgaatat cagggcaatt ttgttttaaa aagagagcca attgacgttc ccgctgtttt
      241 agataacgct taataaagcg aagatttttt tgaaacatcc cattttctaa ataaagagct
      301 aatgcttttt gcattagtaa gttcgtgtct aaatcaatca gtgatttttg ggttaaaaaa
      361 taaggtttta aacctgacgg taaaactaga gctccgatac ggagtgcagg aaaaacactc
      421 attgaaaaag attttaggta gatgattcgg tgatgagtgt cataataatg aattggtggc
      481 tctttaagtt tcacaaaatc tcctaaataa tcatcttcta aaatataaac ctggtatcgt
      541 tgtgctagac gaacaatagc ttccttttcc ttagtgctat aagaaagtcc cagaggatgt
      601 gaaaatcgtg aaatcgtgta aaaaaattta atatcgccag tttgaaataa agattctaag
      661 agttctaaat caaggccatt aaagtgtcta gagatagttt gatagggtaa tcctaactga
      721 gcaacaatag cttccatccg atgataagta ggcttttcaa ggagaattgt tttgcccgca
      781 ttaggaaaag gcatttgtga taaaatataa agcgcttgtt gcgtcccaga ggtgattaat
      841 agttggtctt tgttactgta aacactattt tcagctaagt aaagaagcaa agcttccctt
      901 agttcttcta gtccctcggt tttgtaataa taatgaaaga ggtatttgtc tttagcactt
      961 aaggcctcat ttaagcagag tcggaaatct tcataagcca tattattata atcttcaaga
     1021 cttagattaa gaacattatc gggcatgctt acgttaccca aaacataata accactttta
     1081 ggaacagcat aaattaagtg acgatatttt aattctaaaa gagcccgctg aacagtatct
     1141 ttgctacaat gataaacctt acttagtacc ctaattgaag gtagcttgtc cccttttttt
     1201 agtcgctgtt tctggatatc ttgttcgata ttggaaatga ttgtttgata ttttgttgtc
     1261 ataaattgtc cccatacagt taagtgttat aactattgta tcttatgcct ctttttctta
     1321 caatagttat tatagaaaag aggtaatagc tatgaaacgg attattgtgg caaatgatct
     1381 ggttggtgtt ggtaaggtag ctttgtctgc tagtattcct ttaatggctt cttgtttgtt
     1441 agagcaagtt ttattaccaa cttgcctttt atcaagccat actggcggag gacagagccc
     1501 tgtgaagcat actacatcaa gtatattaga cgttttttta acagattggg acaacaaaag
     1561 aattaagttt gacggcatct ttataggtta ttttacgaca acaagagatg ggcaaaagct
     1621 actagaatgg ctttcaagaa agcaactttc cctaatttta gatccaatta tggcagataa
     1681 tggaaaactt tatcaaggct tcagtcaaaa gcatatagag attatgataa aacttactca
     1741 aaaagctgag cttgttttac ctaatattag tgaggcttgt ctattaacgc aaacagctta
     1801 tttagcaaaa aattatgatg aagaagatat tagacaggtg gctagaaaat tagctaagct
     1861 tggacctaaa caggttgtca ttagcggaat ctcttttgag gagggcagca ttggttttgc
     1921 ttactatcag tcagattcag atcaattaac attccatttt gggaagcaat tcccttacca
     1981 tttctatggt acaggagata tagcatcagc tattataaca gcaggattct attatcagct
     2041 accactaaca caaattctag atcttgttgt ttcatttctt gaaaaagtat tgcaaaatac
     2101 ccttacatta aaaagagatt taatcttagg tgttgcttat gaatctcatt tagattactt
     2161 aactaaatcg tttaaaaagt tgttggagga aaaaaatgtc atctcaaaaa ttagctaatt
     2221 atattgaatt gagtatgtat gctgctttaa tttttatttc agtacaagtg ttgcgtatcc
     2281 ctgtcggtat gcagtttatt catcttggca atgcattagt tgttattgca gtcttaatct
     2341 atggtagtaa aaaaggagct ctagttgcta gtcttggttt agggatcttt gatgttttga
     2401 acggctatgc ttcagtcgtt tggataacta tcttagaatc cttagctatt tgtttaattt
     2461 tgcatttggt atatgaaaga gctatgcaat ctagtaaaaa accaaaagcc attataacaa
     2521 taacagttat tgctgcattg tcaaaattaa ctattaacct tataaaatac ttactgttag
     2581 cttatatagg tactcagcta ccactttcgg tatctttttg ggtagctctt ggaaaaattg
     2641 gtggtagttt cggaacatct tttgtgactt tagttgctgt tcctcttttg tatcctgtta
     2701 tcaaaaactt aaaagaaaag gttacaatcg gacaagcaaa aagaggtttt tgatacaagt
     2761 accttatcga taaaaaagca aggtacactt ttagtcaaat attgacaaaa ggttacaatt
     2821 ttgccataat gaaataacta taaagccgtt ttgacggctt ttttgatgac agttaaggaa
     2881 gaaacgatga gtattttaga agttaagcag ttgagttacg gttttgggga tcgggctatt
     2941 tttgaaaatg tgtcatttcg cctcttaaaa ggcgaacata ttggactagt tggggcaaat
     3001 ggtgaaggaa aatcaacctt tatgagtata gtcacaggac atttacagcc tgatgaagga
     3061 aaggtagagt ggtcgaagta tgtcactgca ggttacctgg atcaacatac agtgttggaa
     3121 tcaggacaaa ccgttcgtga tgtcttgcga actgcttttg atgagttatt taagaccgag
     3181 aatcgtatta atgagattta cgcgtcaatg gcagatgata aagctgatat tgctgttttg
     3241 atggaagaag taggtgagct tcaagaccgt ttagaaagtc gtgatttcta tactttggat
     3301 gctaagattg atgaagtagc gcgtgcgctt ggtgttatgg attttggaat ggagtcagat
     3361 gttacatcct tatcaggtgg gcaacgaaca aaggttttat tagccaaatt actattagaa
     3421 aaacctgata ttctgctatt agatgaacca actaaccatt tggatgctga gcatattgaa
     3481 tggttaaaac gctatttaca acattatgaa aatgcttttg tgttgatttc gcatgatatt
     3541 tctttcttaa atgatgtgat taatattgtt taccatgttg aaaatcaaag tttagttcgc
     3601 tatactgggg attattacca atttcaagct gtttatgaga tgaaacaatc tcaacttgaa
     3661 gcagcctatg aacgtcaaca aaaagagatt gctaacttgc aggattttgt caaccgaaat
     3721 aaggctcggg tagcgacacg taacatggca atgtctcgcc aaaaaaaact tgataagatg
     3781 gatataattg aacttcaagc tgagaaacca aaaccaaatt ttgaatttaa gcaagctaga
     3841 actcccagtc gattcatttt tcaaacaaaa aatcttgtga ttggttatga ttacccattg
     3901 accaaagaac ccttaaatat aacgtttgaa agaaatcaaa aaattgctat tgttggggcc
     3961 aacggtattg gaaaatctac tttgctaaaa agtttattag gtgttatcga gcctttagaa
     4021 ggtcatattg tcacagggga ttttttagaa gttggctact ttgaacaaga agtgacaggt
     4081 gttaaccgac aaactccgct agaagtagtt tgggatgctt ttcctgcctt aaatcaggca
     4141 gaagttcgag cggcactagc tcgttgcgga ctaacatcaa aacatattga aagtcaaatt
     4201 caagtacttt cgggtggtga acaagcaaaa gttcgttttt gtttgttgat gaatcgtgaa
     4261 aataacgtgc ttattttaga cgaaccaaca aatcatcttg atattgatgc taaaaatgag
     4321 ctcaaacgtg ctttaaaagc atataagggt tctattttaa tggtttgtca tgaacctgat
     4381 ttctacaatg ggtgggtaac cgatacttgg gattttagta agttaaccta aactattcct
     4441 taatttttta cacaggaatt actaaaatca gtaaagatat agaataaata ctgctagata
     4501 tgtgatggtt taggtaactg atcaccaacc aaaaaagatg tgactacatc tttttttatc
     4561 taatggaatg gtgtaaagtc gtttaataat agcttatttt ttgatgatca gttgttcatg
     4621 aaattgttgg tgattaacaa gtcatttaag atacaaacgt tattactaaa aagtgattca
     4681 aatagtttcc ctatttttat gtttttttaa aatttattac gaataaatag ataaagacag
     4741 tgaagatgat tagtaagtac atctgctaag attacgaata gatggggaca ataaatgacg
     4801 aatttaacgt tttatgcaaa aatcggtatt tcagaagaag agcatgactc ttttgttaaa
     4861 gaacatcagc aaattagcgt tttacaaggt agtgattggg caaaaatcaa aaatcaatgg
     4921 cagaatgagc gaattggtat ctataaagag gaaaagcagg ttgcctcttt atcacttttg
     4981 attaagctat tgccacttgg aagaagcatt atttatattc caagagggcc agtcatggat
     5041 tatcttgacc gtgatttggt ggcatttacc atgaaaacac taaaggatta tggtaaaact
     5101 aaaaaggccc tctttatcaa atatgatcca gctatcctgt taaaacaata cgcactggga
     5161 caggaagaag aagaaaaacc tttagcttta gcagctatta agaatctcca agaagctggt
     5221 gttcattgga ctggtttaac aatggagatt gcagatagta tccaacctcg tttccaagct
     5281 aatatttaca ctcaagaaaa ccttgagatg caatttccta agcataccag acgtttaata
     5341 aaagatgcta agcagcgtgg tgtagaaaca tatcgtgcca gtcaatcaga acttcacaaa
     5401 ttttccaaga ttgtctcctt aacagaaaaa cgtaaaaata tttctttgcg taacgaagct
     5461 tactttcaaa agttgatgac tacttatggg gataaggcct acttacatct agcaaaagtg
     5521 aatattcctc aaaaactaga tcaataccgc cagcaattaa ttcttattaa ccaagatatt
     5581 actcgcaccc aagctcatca aaagaagcgt ttaaaaaaat tagaagatca aaaagcttct
     5641 ttagaacgtt atataactga atttgaaggc tttacagacc aatatcctga ggaagttgtt
     5701 gtagcaggta tattatctat ttcttatgga aatgttatgg aaatgcttta tgctgggatg
     5761 aatgatgatt ttaagaagtt ttatcctcag tatctgctgt atcctaaagt ttttcaggat
     5821 gcttatcaag atggtattat ttgggctaac atgggaggag tagaaggctc gcttgatgat
     5881 ggacttacca aatttaaggc caactttgct ccgacaatag aagaatttat aggagaattt
     5941 aatctccctg tcagcccact ttatcatatt gctaatacca tgtacaaaat acgaaaacag
     6001 ttaaagaata aacattaaaa gactcgccaa aatgagcgag tcttttaatg tttattctgt
     6061 tattcccatt caactgttgc gggtggttta cttgtgatgt cgtagacgat acggttaacg
     6121 tggtcaactt catttacgat acgtgttgag atttttttca agacatccca aggaagttga
     6181 gcaaagtcag ctgtcatacc atcaatagac gtaatagcac gaatggcgat ggtataatca
     6241 taagtacgac catctcccat gacgcctaca gaacggacac ctgtgttaac tgtaaagtat
     6301 tgccacacgt cacgatcaag tccagcctta gcaatttctt cacgaaggat agcgtctgat
     6361 tcgcgaacgg tttcaagttt ttcttcagta attgctccca tgacacggat agcaagtcca
     6421 ggacctggaa atggttggcg ccaaacaatt tcttcaggca ttccaagagc gattccaagc
     6481 gctcgaactt catctttgaa aagagtgttt aagggctcaa tcaattcaaa ctgcatgtct
     6541 tcggggagac cacccacatt gtgatgtgat ttgatggttt gagcagtttc tgttcctgac
     6601 tcaatgatat cagtataaag tgttccttgg gcaaggaagt caacaccttt taatttgctg
     6661 gcttcatcat caaaaacata gacaaattca ttaccaataa ttttacgttt tttctcagga
     6721 tcttcaacgt ctgcaagaag gtctaagaaa cgttttgaag catccacacg gataatattt
     6781 aggccaaatt tgcccccaag cattcccata acttgatcgc cctcgtcttt acgaagaaga
     6841 ccgtgatcaa cgaaaataca agttaattgg tcaccgatag ctttttgaag tagaacacca
     6901 acaactgaag aatcaactcc accagaaaga cctagaagaa ctttacgatc gcctacagtt
     6961 tcacgaattt tagcaatttc catgtcaata aaattatcca ttgaccaatc accacgcgcg
     7021 ccacaaattg atatagcaaa gtttttaaga atgtcatttc cataaacaga gtgtctcact
     7081 tctgggtgga actgaatacc gtaaaggttt ttctcagtat tttcaatagc tgcataggga
     7141 cagtcatttg agtctccaac aaggtggaaa ccttctggaa tttcagtaac agcatcacca
     7201 tggctcatca aaacgagttg ttcttgaggt gtgcctgaaa ataattttga cgtttcacga
     7261 agatgaaggg ttgactgacc gtattcacga ttaccagctt gtccagcagg aacaacttta
     7321 ccacctaatt tatgggtgat taattgcata ccgtaacaga taccaagaat cggaatccct
     7381 agttcaaaga tttcagggtc aatgccaaag gcgttatcag cgtaaacaga gttaggccct
     7441 cctgataaaa cgatacctat gggattgatc tcacgaagtt cttgagcggt gattttatgg
     7501 ctttttagtt cggagaaaac accaaactct cgaatacgtc tagcaataag ctgattgtac
     7561 tggctaccat aatcaagaac gataattttt tgaacatcat tcaaaattga aatttcagtc
     7621 attataatcc tttcattcta taccaaccgt caggctgata gttgtcaact tattgtagca
     7681 tattttcatc gaaaagacat tacaatttct ctagctcgtt ggaaaaaaac gtaatcgtta
     7741 tgttacaata gaggctatga aagggaatta agacaacagg gagggcctat gctaagaaaa
     7801 aagagaattt tgggtttatt tcgacctgtt gaattaattt tcctaggatt attgttgagt
     7861 ttagttgttt cgtaccttgc gtggaccaat agttttgcaa cacttcacaa tatattagca
     7921 actgtcggaa tagtggaacg aagcaaagat caacagcctc gctatcacat tggacaagct
     7981 attcaagtac aaaaaagtgg tccatatcat caatggattg gaactattaa taaacaggta
     8041 gaagatatag ccgaaaatta ccgagtgagt tatcattatg aagtggtatt tccaatagga
     8101 aaagtcactg tttctttgcc agaacataac ctgaaagagc ctgataaacc gaggtttaaa
     8161 aaaggagata tcgttaaatt atcttcatta actaaaaagc cacatataaa agtgtatcaa
     8221 ggtcaattag cgactattaa acaagttaaa aaacgctatg actattcgtt aggaggatat
     8281 cagtacgata ttaacctgaa agataatcta agattagatg gaatttcaga gcaagatttt
     8341 gttaaacctt attatattag gttcaataaa ggaaattccc ctgagcaaaa caatcgtctt
     8401 ttgcgaaaag ctttcgctta tgcaaagcag catccaaata gcgttatatc ttttccaaag
     8461 gggcaatttc acattggctc tttgccttca caaaaagatt attttgagct tccatctgat
     8521 acagctatta ttggtcatca gacagagttc attattcacg gtaaaatgtt gtggtttgga
     8581 ttccctacag gaccaaaggc tgaacaaggt gttcgtaatc tcgtgttgac tggagtgcat
     8641 ttcaaagcaa atgatttgaa aaaaggagac cactttatga ttatggctga tcatggtact
     8701 gattggcata tttacgataa caaatttact atggttcata agcgtaatag tcatattttt
     8761 gatttaggat ctctacaaaa ttcattgttt gagaaaaacc aatttattgg ctatgcgcca
     8821 gaattagtac aagaccaaca gctgctatca aaggctcaag ggcatgattt tttttcagaa
     8881 gtcattcagt ttgatgctgc tgttcatcat tttgcatggg atggaggtct acttagtaat
     8941 attgctccaa actatgaagc atttaaccaa actcgacatc tatgtcacaa tattactgta
     9001 agccaaaatc aatttttacc ttatatagat ccgactggtt gcctgagagc ctatagtggt
     9061 tctattggtc agcattcctc aaaggtagga gttattaggg ttttaaataa tgtttttacc
     9121 tcatccattg ttactaaagc gaagctcact agttggttta tggaacctat tcattttcca
     9181 ccaaattcac cagttattgt cgcaggtaat atcattaatt gatgccaaat acctcaatat
     9241 ttacaattca attctcatca aaaatatgat aaaatagatg aataaccgac ttgaggagtg
     9301 tggcatgtta ccagcttata taaaaattca tgatgcaatt aaaaaagaca ttgatctggg
     9361 catctggcca attggtagtc gcttaccaag tgaacgacat ttagcggaac atttcaccgt
     9421 tagtcgaatg actctacggc aggctattac attactagta gaagaaggga tccttgaaag
     9481 gcggatagga agtggtactt atgttgccag tcatcgtgtt caagaaaaaa tgcgaggaac
     9541 aacaagtttc acagaaatta tacgctccca aggacgacaa ccctcctcta aattattatc
     9601 ctatcaaaag caattagcta gtgataccga agttaaagaa ttgaacttag acaaaacaga
     9661 cttggtcatt cgaatggaac gtatccgcta tgcagacagt gtccctttgg tgtacgaaat
     9721 tgcttcaatc ccagaaaaat ttataaaaac ggttaaacga gctgatatta cagaacactt
     9781 ttttcactca ttgatagcaa atggttacga gattggtaaa agtaaacaga caatctacgc
     9841 taagctagca agtgagcgtg tagcctccta cttggaagtt gctaaaggac atgccatttt
     9901 ggctctaact caggtgtctt actttacaga cggcaaacct tttgagtatg tccgcagtca
     9961 gtatatcggt gaccgttttg aattttactt agaaaataat tagtaaagaa gtcatttatg
    10021 acttcctttt ttacacgaac agcataaggc aattaatttg ctactgttaa aaacaatcat
    10081 agtatgataa aatgaacatt atggaaattg aaaaaacaaa caggatgaat gccctttttg
    10141 aattttatgc agctttgcta acagataaac aaatgaatta tattgaactg tattatgccg
    10201 atgattatag cttagctgag attgctgatg aatttggtgt cagtcgtcag gctgtctatg
    10261 ataatattaa gcgtacggaa aaaattttag agacttatga gatgaaactt catatgtatt
    10321 cggattatgt tgttcgaagt gaaatctttg acgacatgat tgctcactac cctcatgatg
    10381 agtatttgca agaaaaaatt tccattctaa ccagtattga caatagagag taagaggagt
    10441 tttgactatg gcttttgaaa gcttaaccca acgtttgcaa gatgtgttta aacacattcg
    10501 cggtaaaaag aaattatcag aatcagatgt tcaagaagtg acaaaagaga ttcgtctagc
    10561 tcttttagaa gccgatgtcg ctttaccagt tgttaaaacc tttattaagc gcgtacgtga
    10621 gcgcgctatt ggccatgaga ttattgatac tcttgatcca acacaacaaa ttcttaagat
    10681 tgttaatgaa gaattaacga gtattttagg ctcagaaact gcagagattg ataaatctcc
    10741 caaaattcca actattatca tgatggtcgg tttgcaaggg gctggtaaaa caacttttgc
    10801 aggaaaactc gctaataaat taattaaaga agaaaacgcg cgaccactga tgattgctgc
    10861 cgatatttac cgtccagcgg ccattgatca gttaaaaaca ctggggcaac aaatcaatgt
    10921 acctgttttt gatatgggga cagaccactc agcagtcgat attgtcagaa aaggtttgga
    10981 acaagctcgt gaaaaccgca atgactatgt cttgattgat actgcgggtc gcttgcaaat
    11041 tgatgaaaaa ctgatggaag agctgcgcga tgtcaaggct ttagcacaac caaatgaaat
    11101 tcttttggtt gtagatagca tgattggtca agaagctgcc aatgtagcct acgagtttaa
    11161 tcatcagttg agcatcacag gggttgtgtt aacaaagatt gatggtgata cacgtggagg
    11221 tgcggcgcta tctgtccgtg aaatcactgg aaaaccaatt aaatttacag gtattggtga
    11281 aaaaatcaca gatattgaaa catttcaccc agaccgcatg tccagtcgga ttttgggaat
    11341 gggggatttg cttaccctca ttgaaaaagc tagccaggaa tatgatgaga aaaaatcctt
    11401 agagttagct gaaaaaatgc gtgaaaacac ctttgatttc aatgatttta ttgaacagtt
    11461 agatcaagtg caaaatatgg ggcctatgga agacctcttg aaaatgattc caggaatggc
    11521 tggtaaccca gctttggcca atatcaaagt tgacgaaaac caaattgctc gcaaacgtgc
    11581 tattgtctct tcaatgacac ccgctgaacg tgaaaatcct gacttactaa acccgagtcg
    11641 tcgccgtcgt attgcagctg gttccgggaa cagctttgta gaagttaata aatttatcaa
    11701 agactttaac caagccaaaa gcatgatgca aggggttatg tcgggcgata tgtctaaaat
    11761 gatgaaagat atgggtatta atcccaataa tcttcctaaa aacatgcctg ctggtatgcc
    11821 agatatgtct tccttagaag gaatgatggg acaaggtggt atgcctgatt tatctggcct
    11881 cggtggtgat atggatatga gtcaactatt tggtaaaggg tttaaaggaa aaattggcca
    11941 atttaccatg aaacaggcca tgaaacggca ggctaacaaa ctaaaaaaag caaagaaaaa
    12001 acgaaaataa aagagacgaa aattttcgtc tctttttgat gtgaaattca tttatcttgt
    12061 atacaagatt attaaaatta cggaagaccg tgttacatac catgatgagt tcattatcaa
    12121 tctaacttaa atttctaagg gcctaaaatt agcgataatt ttgccaataa tgcgaggttc
    12181 ttcgctatag ggagcaaact tatcagaata ttttttattt aaggacacta gacgtaatcc
    12241 ctcatcttca cgaaatacct ttttgatata tgtttgccca tcccattcga ctgcataaat
    12301 tgctccatcg taatcaaaac tattttgttt tataagaaca acttcaccat ttaaataagt
    12361 tggctccata gaatctccaa aaacccaaga cgcaaaatcg tattctaatt gttcatcgta
    12421 aaagacaaca tcaaagttac catcaccaaa ataggagtaa ccagtaccag cagataaact
    12481 ttcatagacc cgataagcat ataattgtga tggtttatct atgagatctt tagatttttt
    12541 gtctatttga tgatttaaca atcgctctga atagccaatt actttttctt tattagatat
    12601 tgtcagctgg ttataaggcg ttagcaatct atagtttggg tcgaaataat cagatgtcac
    12661 attgaataga tgcaataagg catttaaatg tttttcattt ggtatattct tacctttttc
    12721 ccaattagat attgtcattt tattgacatg caacaatctt cccaattctg attgagttat
    12781 tccctttgat aatcgtgctg tttttagttg atgtccagaa aacatttggt agctccttta
    12841 gtaaagttat aactttacta atagtatcaa aaaaataaaa cgaaagcaag tgtaacattt
    12901 tctacaatta attcatgtga tagtaacact gtcaaaaagg gggaacacct aaaacataac
    12961 atagcgacta gattcgtgta ctagcaggtc tatatctgat aaagagttaa ttactttaaa
    13021 gataaaatta tcatttagtt ctgagct
//
LOCUS       DAUGOH010000045        10724 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUGOH010000045 DAUGOH010000000
VERSION     DAUGOH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10724
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.045"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            199..1269
                     /gene="xerS"
                     /locus_tag="VH957_001453"
     CDS             199..1269
                     /gene="xerS"
                     /locus_tag="VH957_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEQ8559353.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTKAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
     gene            1970..2452
                     /locus_tag="VH957_001454"
     CDS             1970..2452
                     /locus_tag="VH957_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEQ8559354.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            2541..3593
                     /gene="citC"
                     /locus_tag="VH957_001455"
     CDS             2541..3593
                     /gene="citC"
                     /locus_tag="VH957_001455"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEQ8559355.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYTLGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAVVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWELLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(3703..5097)
                     /locus_tag="VH957_001456"
     CDS             complement(3703..5097)
                     /locus_tag="VH957_001456"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEQ8559356.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDSRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEDIKEKII
                     GDEAVITCRPADLIEPQMIYLRDEIAPYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(5112..5690)
                     /gene="citX"
                     /locus_tag="VH957_001457"
     CDS             complement(5112..5690)
                     /gene="citX"
                     /locus_tag="VH957_001457"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEQ8559357.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            complement(5683..7215)
                     /gene="citF"
                     /locus_tag="VH957_001458"
     CDS             complement(5683..7215)
                     /gene="citF"
                     /locus_tag="VH957_001458"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEQ8559358.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEGLVEKILDVQDFDHP
                     SAVSLGKHAEHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLADHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            complement(7218..8105)
                     /gene="citE"
                     /locus_tag="VH957_001459"
     CDS             complement(7218..8105)
                     /gene="citE"
                     /locus_tag="VH957_001459"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEQ8559359.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENGIEVGRTRMMAAIESAEGVLNARDISKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            complement(8093..8401)
                     /gene="citD"
                     /locus_tag="VH957_001460"
     CDS             complement(8093..8401)
                     /gene="citD"
                     /locus_tag="VH957_001460"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEQ8559360.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
                     "
     gene            complement(8589..9710)
                     /locus_tag="VH957_001461"
     CDS             complement(8589..9710)
                     /locus_tag="VH957_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8559361.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIETELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            complement(9755..10150)
                     /locus_tag="VH957_001462"
     CDS             complement(9755..10150)
                     /locus_tag="VH957_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ8559362.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVGEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            complement(10207..10530)
                     /locus_tag="VH957_001463"
     CDS             complement(10207..10530)
                     /locus_tag="VH957_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559363.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSAIAAGDRPNSQFKVKRILKRNSEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
BASE COUNT         3215 a         2117 c         2130 g         3262 t
ORIGIN      
        1 atctaaaaga agtgacgtta gtatctgtaa aaaagagatc tgtctcgtaa catctttccg
       61 aaaaactgta attttcttga aaaatattta taggtgtgat atactgctct tgtagagaat
      121 gaatgacata aaatacatga gacaatttgc gaaaattcat ttttgaaaaa attgttatta
      181 ttaaggaatt atgatgatat gagacgcgaa ttattactag aaaaaattga aacctataag
      241 gccatcatgc cttggtatgt tttagattat taccaatcca agttagctgt tccatacagc
      301 tttaccacct tatatgagta tttaaaagaa tacaaacgct tttttgattg gctgatggat
      361 gctgatttaa cgaaggcgcc aaagattgct gatattgact tgagcacgct tgagcacctt
      421 accaagaagg atttagaggc ctttgtgctt tatttgcggg aacgaccttc tctcaacacc
      481 tattccacca aagaggggct ttctcaaacc actattaatc ggaccttgtc tgccctatca
      541 agcctttaca agtacttgac tgaagaggtt gaaaatgacc aaggggagcc ttatttttat
      601 cggaatgtta tgaaaaaagt gtcaacaaaa aagaaaaaag aaaccctggc ttccagagcg
      661 gaaaatatta agcagaaact gtttttaggt gatgaaactc tagctttctt ggattatgtg
      721 gataaggaat atgagcaaaa attgtctaat cgtgccaaat cttctttccg taaaaataag
      781 gagagggatt tggctattat tgctctacta cttgcttctg gtgttcgttt gtctgaagca
      841 gtgaatcttg atttaaaaga tgtcaatcta aatatgatga ttatcgaagt tattcgcaaa
      901 ggcggaaaac gtgattcagt caatgtagca ggttttgcga aaggttattt ggagtcttat
      961 ttagctgttc gtcagagacg ttacaaggct gaaaaacagg atcttgcttt ctttttaaca
     1021 gaataccgtg gcgttccaaa tcgaatggat gcttctagta tagaaaagat ggttggcaag
     1081 tactctgagg attttaaaat tcgtgtgact cctcacaaat tgcgtcatac gctagcgaca
     1141 agactatatg atgctactaa atctcaggtg ttagttagtc atcaattagg ccattcctct
     1201 actcaagtca cggatcttta tacccatatt gtcaatgatg agcaaaaaaa tgctttagat
     1261 aacctttaat attacataat tatttttatg taatattaaa ggtaaaaata gcttcaaaat
     1321 taactttaat agatggctac tattaaccgt gacagtttgg tgtcaggccg ttttccaaac
     1381 tactcaagcc acttagaaaa aggaatatca ctgctaactt tgtcccttct ttgaatgact
     1441 ttttttgcga tgtttataga ttaaatctag tagggttctc atcaaaaaga tgagataagc
     1501 ctgtttttag tatgtcagta cttttgttta gtatgataat acgttatttt gtaaagtagc
     1561 ttttaggatt attcttgtta aactacttaa tgtcattact gataacttag agtaatataa
     1621 agctaaaact gaaggaatgt tagagaatca tgaagacagc ttctttaaca tcaattggtt
     1681 gaaaacaaga atcagataac attatcgcta gatagactga aggaatcaaa aacacagttt
     1741 gttacataaa taaattcttg tcaaaacttg tattttctat ttgaactgat acgattgaca
     1801 aaggctaaac taaaatagct tgactttttt agaatctttg tattttttgt cggatcccct
     1861 cctatttttt ccttgaattg atctatttaa ccttttagaa caaggtttat cgcataccat
     1921 ttttagacat tttgttataa taaaaagaaa cgacttgagg agataaaaga tgccaaagag
     1981 aataagaaaa gctctaggag tagttgggaa actgatgtca attgttcctg acactactga
     2041 aattattgga aaaacgattg ataacagtcg accaattatc gaaaaacgta tggaacaaaa
     2101 acatgaaaaa gagatgcaac tacgcacgat agatgatgtg attaatcttc ctgttgatca
     2161 ggcacaagct catttggaac aacttggctt tgtagtagcc actatacctg ctaagcctca
     2221 taaaaaatgg cttcatagta atctcaatga agtggttgct atgtctccaa aatctggtaa
     2281 atataagata ggaagcctga tcaaactcta ctacattact gttgatgttt tggaaaaaag
     2341 tcaagactta ttagaccaag aaaacttgcg gactgtggaa cgcaatcaaa aaatcgctga
     2401 tacttttgag tctgtcaaac acattcgatt tccttttaaa aaatggcgtt gataaaaaac
     2461 agagttgcct ttagatagat cagcctgttt tggtactaag ttatgttatg attcaataaa
     2521 attaaagata aggagaagaa atgccttact acactatttc aaaagtcttt ccttcagata
     2581 aaacgacaat ggctagtgta aagaacctac ttcatcaaga aggtattcgt ttggatgctc
     2641 atttagatta tacttgtgcc atcatgaatg cgcaaaatga tgtgattgct accggttctt
     2701 actttggaaa tagcttgcgc tgtctttgcg tatccagtgc ctatcaaggt gaaggacttc
     2761 ttaataggat tgtgagtcat ctcattgatg aagaatatac ccttggcaac tatcatcttt
     2821 ttgtttatac gaagacctct tctgctgctt ttttcaaaga tcttggtttt actgaaattg
     2881 tccatatcga caatcacatc agtttcttgg aaaataaaaa aactggtttt caagattatc
     2941 tgatgacact taataagcct gagcaaacac ctggtaaagt cgctgctgtc gttatcaacg
     3001 ctaacccctt taccttaggg catcaatttt tagtagagaa agctgcaaga gaaaatgatt
     3061 gggttcatct gtttatggtc agtgaagacc gcagtctaat tcctttttcg gtgagaaaga
     3121 ggttgattca agaaggtcta gctcatcttg ataatgtcat atatcatgaa acaggtcctt
     3181 atttgattag ccaagcgact ttcccagcct atttccaaaa agaagacaat gacgtgatta
     3241 agagccaagc tttgctggat accgctattt ttctaaagat tgctcaaacc ttacagatta
     3301 caaaaagata cgttggagaa gagccaacca gccgagtaac tgctatttac aatgaaatta
     3361 tggcagagca gttgcagcaa gctggtatcc tcctagatat tttgccaagg aaagctatca
     3421 atcagcagca agatcctatc agtgcctcaa cggctaggca ggcattgaaa gataatgatt
     3481 gggaacttct ggcaaaactc cttcccaaaa cgtctttaga ttatttttgt tcgctagaag
     3541 cccaacccat tattaaaaag atacaagcca cttcatctgt caaacattac taagataaaa
     3601 aacctatctg attatcaaaa tcaggtaggt ttttggtatt gttcttacag caaatgcgtt
     3661 tcaccaagga gattaatggt taagaggatt agtcattccc tgttagtctt gaatgtccag
     3721 ttgtacagta acttcttgaa ccggaacatc atagaaagga tcttcacggc gtcccaagaa
     3781 atctctggct tgctgtggga aactcgcata gcttaacacg tcttcttctg aacgagcgta
     3841 tggagcaatc tcgtcacgta gataaatcat ttgaggctcg attaggtcgg ctggtctgca
     3901 agtaataact gcttcgtcac caatgatttt ctctttgata tcctctgcta atggggctgg
     3961 tgattgaccg tatagccctc gaacatagtc tttgatttca tttggaacta ccttgtagcg
     4021 ttcccctgag atgatattca tcaaggcctg tgtgccaacc atttgtgata atggcgttac
     4081 aagtggtgga tatccaagat cggcccttac tttaggtact tctgctaaga cttcttcgta
     4141 tttatcagct aggccttgct cggttaattg gctcaatagg tttgatagca taccacctgg
     4201 aacttggtaa atcaatgttt ttggctcagt gtctttgact ttaggattta aaatccctat
     4261 ttctcgatag tggtcacgaa tagtgttgaa atattctgca actttggcca cctcttgcat
     4321 atccaagcca gtgtcgaagc ccaaatccgt caaggcaatc gccattgact ctgtggcagg
     4381 ctgactggtt ccccctgaaa aagaggaaat cgccgtatca ataatatcag ctcctgcttc
     4441 tgctactttt aagtaagtca tttctgaaat accactggta gcatgggtat gaacctcaag
     4501 agggatagtt gtattctcct tgatacattt gaccaattgg taacctattt caggagttaa
     4561 gacaccagcc atgtctttga tacaaatgga gtcagctccg atagcttggt aagctttcgc
     4621 caattcaaca aagtagtcaa tggtatgtac cggacttgtc gtgtaagaaa tggcaacttg
     4681 agcatgccct ccaaattttt tagtcgctga aacagctgtt tgcaagttgc gtgagtcgtt
     4741 taaagcatcg aagatacgga caatatcaat cccgttttca atggattttt gaataaagga
     4801 tctgaccaca tcgtcagcat aattgcgata tccaagaagg ttttgtccgc gtaagagcat
     4861 ctgaagttta gtctttttca ctgctttacg gatggctctt agccgttccc aagggtcttc
     4921 atttaaaaag cgtaggcagg aatcaaaggt tgctcctccc cacatttcaa gggcatgata
     4981 accagcattg tctagagttt ctagaatagg aatcatttcc ttggttgtca tacgtgtggc
     5041 aatctgactt tgttgaccat cacgtaaaac tgtttccgtt atacggattt tcgtcataat
     5101 tgttctcctc atcaacctgt cttatctgat gacgatgatt ggttgtcttt attgaaaaat
     5161 gaatggagta attttgaaat agcagtctgc atctcctcga cactgtgctt acgtaggcga
     5221 ccgcagactt tggcctcttt agaacagata aaacattgcc taggggagcc tcctaatacg
     5281 gttctgctaa ttgaatgagg cagatcattt tgcaagacca agacatctaa gtccatgaga
     5341 cgacctattg gcaactctgt ctctaaggct atcattttta acttcaggtc gcggctaggt
     5401 agacttgtga tgaggtaata ctcataaccc gttgtaggca gtaatcgcaa ctggtaacaa
     5461 atcttatcgt cagctaaggc agtttgaatg gccttaatca ctatatcaaa agcttcaaga
     5521 agtttaggag aggttttaat tggtccaggg atattcatgg tgaccgataa taagctacct
     5581 tctgggtact cctttaataa atgcagctga cgcagagctc tttcttcgcg ggctcttaac
     5641 atatcactaa gttggatagc ttcgcctgaa aaataagtgt ctttacacat tgtaaaccac
     5701 atccatgagg ctaccatcac ggtattcaat aagagcaaca accttatcac catattgaat
     5761 acgctcaggt gtgccaacga tagcgtaagc cttctctttt agctcctcaa tactaaattg
     5821 tggcacattg agggatttga aatggtctgc taagtcttga cgatttgggt taatggcaat
     5881 tcccacttct gtgacgacca catcgacact tgttcctggt gtaatgaccg tattaacctc
     5941 atctacaaaa gttgggatgc gtccgcggat aagtggtgaa ataaccaaac tcatcttagc
     6001 cgcaaaggca gtgtcgcagt gtcctccaga agcgccacga atcacgccgt cagatcctgt
     6061 catcacatta acattgaagt tagtatcaac ttcaagggct gataaaatac aagtgtctaa
     6121 ttgattgata acagcaccct tgctcaaagg tgaggcatac atgttggcgt caatttcata
     6181 atgttcagca tgcttaccaa gagaaacagc tgatgggtga tcaaagtctt ggacatcaag
     6241 aattttttca accagtcctt cttcgagcaa ctccaccata gcattggtaa taccaccaag
     6301 agcaaagcta gctttgatat tttctttaat catagcttca cgcatgaaac gggttactgc
     6361 caaagaagcg ccacctgttc cagtttggaa agagaatcct tctttgaaat aaggagaatt
     6421 agtgatgacc ttagccgcgt attctgcaat taagagttct ttaggatttt tcgtaaaacg
     6481 agttgcccct ttggcgattc cttgaggatc tccgatagca tccactgtta ccacatagtc
     6541 aacatctgtt tgaggaatgc tgattggggt attaggataa ggaaccaaat tatctgtcaa
     6601 gataaccacc tgatctgcat atttggcatc aatcatggca tagcccaaag aaccacaggt
     6661 tgctttccct tttgtcccat taacatttcc gtaagcatct gaacttgggg cgcccagaaa
     6721 ggcaacatca atatggatat ccccactagc aatggcacga gcgcgaccac catgggagcg
     6781 aataaccaca ggattttcca ttagtccttc tgaaatggct gcccctactt tgtcacgaag
     6841 accagatgaa gtgatgttgg taaccacacc atttttgatg tgatcaatca aaggctcatg
     6901 tacattagcg atggaacttg gagcaataga taggttttta atgcccattt tggcaatttc
     6961 ctccaagacc atattcataa tgaaatcccc ttcacggaaa tggtggtgga atgaaatggt
     7021 cataccatct gttaagccag ttttttcaat cgcttcacgg atagagccta ataatttaga
     7081 atctccaggt ttaactggtt taatacggcg acttgattcg tcatactgtt tgatatttgc
     7141 gagttctcct tcaaagacac catactggtc ggcgtatggt tgaggaatgt cgcgaccgag
     7201 tttatttgtt accatcttta aatgtcctcc tcagataaaa cacctgctgc tgttgctagg
     7261 gcaatgacac gttctgcacg ttcaacgatt ggtttatcaa ccatttttcc atttaaggaa
     7321 ataacgccag agcctttgct ttcagcttca cgaattgccc agatgacttg tttggcatgg
     7381 tcaatttctt tttttgttgg ggtataaatc tcattgacca gaggaatttg acgagggttg
     7441 attactgatt taccgtcaaa ccctaactgt ttgatcatgc gaacttcgtt ttggaaccct
     7501 tcggtattat tgacatcaga ataaacagta tcaatggcag caattccagc agcacgagca
     7561 gcgtgtaaaa tcatgctacg agcaaagaat aattcttgac catctgggta acgacgcgtt
     7621 ttcatattcg tgacatagtc ttctgctcca agagcaatac caatcaagcg cttagaagct
     7681 ttggaaatgt cacgagcatt tagaacacct tcggctgact caatagctgc catcatgcgt
     7741 gtgcggccaa cttcaatgcc gttttcgcgt tcgacacgtt caataacagc ttccacatca
     7801 acaatatctt gggcagtctc tgtttttgga agacgaatca cgttgacacc tgccaaaaca
     7861 acagcttcga tgtctaaagc cccacaagaa tcaagaccat tcacacgaac aaccgtttca
     7921 acgcttgaat aatcaaaagt tttaagcgca aaatggacga gagctctaga ggtgtctttt
     7981 tctttgagtg aaacagaatc ttccaagtca aacatgacgg aatcagcgcc aaataaagga
     8041 gcatctcgaa gcatggctgc attggcacca ggcacaaaca tcattgttct tcttaaacgt
     8101 tccatgagtc aatctccttc caatcatatt ggtcaatacc agcagcgcga tgaacagctg
     8161 cgatggttct cgcttgaatg gtgcaatcta aagcaccttt atcaacagcc tctactttgg
     8221 cagccgtcac cttcaaattc actagggttt gatgaatgag ttgacgaatg tgattgccaa
     8281 attgtttttc aacactactg tctagggtta ttgtaatggt ttgctcgtca ttaggggata
     8341 ctgtaatcat taggtcactt gattcaagtg acccagcaac ggcagtttgt ttaatatcca
     8401 ttgcgtttac ctccttgatt ttcttaaatg atattattat ttactaactg ggaaaagttt
     8461 gatcaggatc tctgcgacaa gatagagaat gcctaacacg ataaagacac ctgccatacc
     8521 aagcgccatt agctcaaagg aactaatcaa atggtctata ttaattgtca ttaggtttct
     8581 ttcctttctt agctaaagta agctagcaac aaaccacctg cgataacaga ggcgatttgg
     8641 ccagagacat tggcacctac agcatacatg aggataaagt tttgcgggtc ttcatctgtt
     8701 gccatttttt gaatgacacg acttgacatt ggaaaagctg aaatacccgc agcgccaatc
     8761 attggattaa tcttctcttt tcggaagaga ttgagaaatt tggcaaacat gaccccaccg
     8821 atagaatcca tgataaaagc aagtaaacca aagacgataa ttaagagtgt ctgtacattt
     8881 aagaacaggt ctgcctgcat tttaatagag atggtcaatc caagcaagat actaataatg
     8941 tttaccaatt cattttgagc agtttgtgac aggcgatcga gcacaccgca ctcacgtaat
     9001 aagttaccga acatcaaaaa gccaactaaa ggtagagaaa ttggggcgat gaaccctgct
     9061 actaaggtaa tgatgattgg gaataagatt ttagtcattt gagatacatt ctcagctttg
     9121 taagtcatac ggatacggcg ctcttttttc gttgtcacta atttaatggc aaatggttgg
     9181 ataataggaa ccagagccat gtaagaatag gctgcaaccg taattggacc cagtaaatcc
     9241 ttggccagtt ggttggcaac aaagatagaa gtcggtccat ctgctgctcc gataatgccg
     9301 attgaagctg cttctttaat gtcaaagcca gccagtacag caacaacaac aacaaagaaa
     9361 atcccaaatt gcgctgcagc accaaacaag agcatgaatg ggttttgaag caagggacca
     9421 aagtcaatca tggcgccaat accaatgaaa atcaacagtg ggaaaagttc tgtttcaatc
     9481 ccaaaattga agagagcctc aaaaacccct tcttgctcga ctccgttaac cacttgggtt
     9541 aaaactcctg aaccagggaa gttaacgaga atggttccaa gtcccatggg gacaagtaga
     9601 gttggttcgt attctttttt aattcctaga tacattaaga gggcaccgat gaccatcata
     9661 acaatttgag gaatggtgat ggaggttatt cctgcgatta aagtgtccac aaattcactt
     9721 ccttttctgt ctatttattc tagttatagt actattaacc aattgtaatg agaccatcac
     9781 caggattgac cacttgacct ggaccgacgt ggatagctgt aatggttcct gctgatgagg
     9841 ccacaatctc attttccatc ttcatggctt ctaaaatcaa tagtggctga ttttcagtta
     9901 cttggtctcc cactgctact aagactttta agatggttcc aggcattggt gatggaatgg
     9961 catccgctcc cgctgcagct actggctgtg gtgcttgcgc ttcccccact tgtgggcttg
    10021 cttcagtagg gacaggtact ggagtggata ttggttgagc gggggcagct gcttgggcag
    10081 gagcgccgat ttcttccatt tctacaagat attctttacc gtcaatggta attttaaatt
    10141 ttcgtaacat catttttctc ctatatgtta ttgtgtcatg agttcgtcta aagtatcgtt
    10201 caccgactac cttttgcaat agatggatgt cacccgaaac tgactttctg ggtaaacacc
    10261 tgcagcgata cttgaagcaa ttaaagaaac agtgattgcc tcagaattgc gcttgagaat
    10321 gcgtttaacc ttgaattgac tattaggtct atcgccagca gcaatagcac tggtaattaa
    10381 agtaaccttt ttgtaatcac ttttgtctgc aggaatataa gcgggaatct tttcccagtt
    10441 ttcagaaggt tctatttctg tactaagggg cgaggattct ttcaacttct cttttttaga
    10501 gtgtttaaac catttttgta aaaactgcat gagctacctc tttttcacat ttacctattt
    10561 agggaactag taagtttatt atatactacc aatctttttt gagatggctt ttttgtgttc
    10621 tttctaagag cgctttcaat gtttcataaa gtttttcaac agttaccttt tattttattt
    10681 ttaggtaact gttgaaaaac tgagatcaag atactgatag caag
//
LOCUS       DAUGOH010000046        10269 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUGOH010000046 DAUGOH010000000
VERSION     DAUGOH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10269
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.046"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..452)
                     /locus_tag="VH957_001464"
     CDS             complement(<1..452)
                     /locus_tag="VH957_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PriCT-2 domain-containing protein"
                     /protein_id="HEQ8559364.1"
                     /translation="MTDDKFDLLPLLDYIDPSKLSYQDWVNVGFALKHEGYTAMDWDI
                     WSQSDSRYKKGECFAKWDSFQGNGLGTVTGATITQLAKENGWTSDYRTSDEAHELDWD
                     STIDRDYKIIDKNWIEAKEIREPTNWSPVHDLITYINTLFESTDKVGYV"
     gene            complement(442..1071)
                     /locus_tag="VH957_001465"
     CDS             complement(442..1071)
                     /locus_tag="VH957_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559365.1"
                     /translation="MGEYCHLKELDGLRFGSLTVINRNRNNSKGGNARWNCLCDCGNK
                     TVVIGSKLRSGYTKSCGCARKNDNAKGYSSTRLYRIWKGMMNRCYNHKNDNYKYYGGK
                     GISICDEWLTFINFRTWSLSNGYKESLTIDRINPKGNYTPLNCRWVSMKMQQNNKTNN
                     RYLSYLGQEYTIAEFSEKLNVTYWTVINQLKLGWSVERIVEEARMKNDR"
     gene            complement(1081..2664)
                     /locus_tag="VH957_001466"
     CDS             complement(1081..2664)
                     /locus_tag="VH957_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ8559366.1"
                     /translation="MQLRPYQEEARSAVQHEWEDGKKRTLLVLPTGCGKTIVFSKIIE
                     DRVRLGERVLVLAHRSELLEQASDKLMTATGLGTALEKAENTSLGSWFRVVVGSVQTM
                     QREKRLSKFPTNHFDTIIIDEAHHAISDGYQRVLQHFDSSNVLGVTATPDRGDKQNLG
                     KYFDSLAYEYSLVDAIKSGYLSKITAVTIPLTLDLSTVSQQAGDFKASEIGTALDPYL
                     EQIADEMVKQCANRKTVVFLPLVKTSQKFRDILNQKGFKAAEVNGESKDRAEVLEDFD
                     NDKYNVLCNSMLLTEGWDCPTVDCVVVLRPTKVRALYSQMVGRGTRLAPGKENLLLLD
                     FLWHTERHELCRPAHLIAKTPEVAQKMVDNMTEETEVTFELLEAEEVASKDVVAEREE
                     ALAKQLAEMRKRKRALVDPLQFEMSINAEDLVDYVPEFGWEMAPVSDKQKNALEKFGI
                     FTDDIGNAGKATKLLERLAKRRETGLTTPKQIRMLERYGFKNVGMWKFEVASNMINRI
                     AASGWRLPKGINAREYQPE"
     gene            complement(2664..3299)
                     /locus_tag="VH957_001467"
     CDS             complement(2664..3299)
                     /locus_tag="VH957_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559367.1"
                     /translation="MTEYNNNFDRELGWDDEITQDSVGFVQLVPGDYQFTVTNMERAR
                     HTPNPKSPGKLPACNKAVVTIQIETSEGIAQLTHNLFLHTTTEGMLSAFFGAIGQKKH
                     GEPLKMNWNTVIGAKGVARINKRKGTGDYADREYDNIKSMIYADEVDWTKVLNKDVAQ
                     PQQMTHQQSAQPTYQGQQAQGTNFAQQPATQSYQQGQMQTPQQPQGGWGGF"
     gene            complement(3321..4055)
                     /locus_tag="VH957_001468"
     CDS             complement(3321..4055)
                     /locus_tag="VH957_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559368.1"
                     /translation="MTENIKEALEYAVNTAHEKPKTILGSDGKEYYDRNKYSLVELKT
                     KYYPKTLNLNTLDSLIDYLKSDMNNINSKRLMVIVEGPREVIVCEEDDDDLNRNVLVT
                     VEAIIPNVQFGRYDSPSDFNISLQSLFVNADDRNTVIEFASALKIENGSEIVDDGIGQ
                     TATIKQGVASLAKAKAPNPVTLRPYRTFSEVEQPSSEFIFRINQLANMALFEADGGKW
                     RLDAINNIANYLKEELADQTNITILA"
     gene            complement(4057..4479)
                     /locus_tag="VH957_001469"
     CDS             complement(4057..4479)
                     /locus_tag="VH957_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559369.1"
                     /translation="MNKTIKLDLSAIGEGGLQEKVDKELEKVFDNILDPNTETKVARK
                     VTITLTMKPDDARQTVSTAMEVKSTLAPQTGVATTVLVGQKDGKVYANELKSAMPGQT
                     YFDDEAVLRTDIGEPIDHLEKGINEDVIDFNKQKKVGN"
     gene            complement(4519..5610)
                     /locus_tag="VH957_001470"
     CDS             complement(4519..5610)
                     /locus_tag="VH957_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ8559370.1"
                     /translation="MQITRGKRARAQRVIIYGPEGIGKSSFAANFPEPLFIDTEGSTD
                     NMDVARMDKPTSYTMLKNQIAWIKANPTCCKTLVIDTIDWAESLIVDDVCAQHGKKGI
                     EDFGWGNGYTYTKEEVGRFLNMLQELIELGINIVLTAHAQMRKFEQPDEMGAYDRWEL
                     KLGKKTSSQTAPLVKEWADMVLFANYKTVVMTSESKKKKATGGQRVLYTQHHPAWDAK
                     NRHGLPDEMPLDYAVIAHLFAQVPTQPVPQTPPVQETPASQTAHESVHEQAEKAPEQP
                     PMQPTSAPVAYPPSMPKALTDLMSAEQVTPDELVAVANIRGHFPPMTPIENFPSDYWN
                     MIVANWLATLEVIKTQVRTVEPPFTVEGA"
     gene            complement(5625..6944)
                     /locus_tag="VH957_001471"
     CDS             complement(5625..6944)
                     /locus_tag="VH957_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8559371.1"
                     /translation="MSITINKLEIENVKRIKAVKIEPSATGLTIIGGNNNQGKTSVLD
                     AIAWALGGNKYKPSQAMREGSQVPPTLKITMSNGLIVERKGKNASLKVIDPNGQKGGQ
                     QLLDSFVEELAINLPKFMDSTPKEKADVLLEIIGVGDQLAELELKEKEIYNQRHAIGV
                     IADQKEKFAKEMTYYPDAPKQLVSISELIQQHQAILAKNGENAQKRQNVERIRYDYNQ
                     SILEVDRLRKLLADAEAKTNKLSEDLKIANTDAMDLHDESTAEIEANIADIDEVNRKV
                     RANFDKDKAEEDAKQQREQYNILTNDIESIRQQKRDLLINADLPLEGLSVDDGKLLYL
                     GQEWDNMSGSQQLIVATAIVRKLKPDCGFVLIDKLEQMDNITLEQFGKRLEQEGLQAI
                     ATRVSIGEECAIIIEDGYSVENKAHNFKTAEGGNFAETVAPTWKGEF"
     gene            complement(6944..7171)
                     /locus_tag="VH957_001472"
     CDS             complement(6944..7171)
                     /locus_tag="VH957_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559372.1"
                     /translation="MKQQLINDNEFLRDENRRLNNELAEHYFVVTAKANLLDVIIASD
                     FILKSTLDKCIAELDEIDQIALLKAWNKGEL"
     gene            complement(7295..7432)
                     /locus_tag="VH957_001473"
     CDS             complement(7295..7432)
                     /locus_tag="VH957_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559373.1"
                     /translation="MKNKKEQWTPKVHCFRKDGSQCEPENITVPISFAGYYQILLELG
                     V"
     gene            complement(7501..7731)
                     /locus_tag="VH957_001474"
     CDS             complement(7501..7731)
                     /locus_tag="VH957_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8559374.1"
                     /translation="MTINLKRLKAERIASGMTQCEVAQSMGWKTRTPYAKRENGIVSI
                     GADELAKITLIFGLPIEKIAIFFDKDVPVMER"
     gene            7915..8676
                     /locus_tag="VH957_001475"
     CDS             7915..8676
                     /locus_tag="VH957_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8559375.1"
                     /translation="MRTNSEIISLIQSKVEERKMSMSELARNVGIAKSTMSRYFNKTR
                     EFPLNRADDFAKALNISTEFLLGIDLNSEVDGSELLGIYRELEEQRRVIVLDTAKEQL
                     EEQTKIINFSDKKTDIEDIFEVKGTTFAAAASGFGRGFEADDYDTYTVYTDEEPPHYD
                     YAIGIRGDSMLPKYEQGDMLYIVDKGMSTYSGQLCIVVHNGNTYFKKVYTEHDGLRLV
                     SLNKKYSDIFIGYPPAEDTYIKIYDVVGSFTPIEF"
     gene            8703..9068
                     /locus_tag="VH957_001476"
     CDS             8703..9068
                     /locus_tag="VH957_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559376.1"
                     /translation="MTLKQLLKSKNLGEYFEAKNNAEKMNEIENRGLKQVMKNSVRQT
                     QLNSEIKQVIKKEKEAVRCPKCKSTNVGFMQQGKKTFSVKKAVAGTLLIGGTVMGFLG
                     EKGKKQWHCNECSCIFETK"
     gene            9192..>10269
                     /locus_tag="VH957_001477"
     CDS             9192..>10269
                     /locus_tag="VH957_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEQ8559377.1"
                     /translation="MRKVAIYSRVSTINQAEEGYSIQGQIEALTKYCEAMEWKIYKNY
                     SDAGFSGGKLERPAITELIEDGKNNKFDTILVYKLDRLSRNVKDTLYLVKDVFTANNI
                     HFVSLKENIDTSSAMGNLFLTLLSAIAEFEREQIKERMQFGVMNRAKSGKTTAWKTPP
                     YGYRYNKDEKTLSVNELEAANVRQMFDMIISGCSIMSITNYARDNFVGNTWTHVKVKR
                     ILENETYKGLVKYREQTFSGDHQAIIDEKTYNKAQIALAHRTDTKTNTRPFQGKYMLS
                     HIAKCGYCGAPLKVCTGRAKNDGTRRQTYVCVNKTESLARRSVNNYNNQKICNTGRYE
                     KKHIEKYVIDVLYKLQHDKEYLKKI"
BASE COUNT         2990 a         2001 c         1826 g         3452 t
ORIGIN      
        1 acatatccga ctttgtcagt tgattcaaaa agagtgttga tgtaagtaat caaatcgtga
       61 acgggtgacc agttagtagg ttctctaatt tcttttgctt cgatccagtt cttgtcaata
      121 attttatagt cacgatcaat agtgctatcc caatcaagct cgtgggcttc atcactcgta
      181 cggtagtcag atgtccaccc gttttctttc gctaactgtg tgatagttgc gccagtgaca
      241 gtcccaagtc cattaccttg gaaactatcc catttagcga aacattcacc ctttttgtat
      301 ctactgtcag actgtgacca aatgtcccaa tccatagcag tatatccttc gtgttttagg
      361 gcaaaaccaa cattcaccca gtcttgatat gatagttttg atggatcaat ataatcaagt
      421 aaaggtaata aatcaaattt atcatctgtc atttttcatt ctcgcttctt ctactattct
      481 ttctacactc caacctaatt tcaattgatt tattacagtc caataggtaa catttaactt
      541 ctctgaaaat tcagcaatag tatattcttg acctaaatat gataaatacc tattattcgt
      601 tttattgttt tgctgcattt tcatacttac ccatctgcaa tttagtggag tatagttacc
      661 ttttggattt attctatcaa tggttaatga ttctttatat ccattagaga gcgaccatgt
      721 tctaaaatta ataaaagtta gccattcatc acagattgaa ataccttttc caccataata
      781 tttgtaatta tcgtttttgt ggttatagca tctattcatc atgcctttcc aaattctgta
      841 aagtcttgta gatgaataac ctttagcgtt gtcattttta cgtgcacatc cacatgattt
      901 tgtataacca cttcttaatt tacttccaat aacaactgtt ttatttccgc agtcgcaaag
      961 acaattccat cgtgcattgc cacccttaga attgttacgg tttctattaa tgactgtcaa
     1021 tgatccaaat ctaagtccat ctaattcttt taagtgacaa tattctccca tttttgtctc
     1081 ctattcaggt tggtattctc gagcattgat gccttttggt aggcgccatc cgctagcagc
     1141 aatgcggtta atcatgtttg atgctacttc aaatttccac attccaacgt ttttaaatcc
     1201 gtatcgttct agcattctga tttgtttagg tgttgttagg ccagtttctc tcctcttggc
     1261 caatcgctcc aataatttag tagctttacc tgcatttcca atgtcgtcgg taaaaatacc
     1321 aaatttttct aaagcgttct tttgtttatc agaaacagga gccatttccc agccgaattc
     1381 tggtacatag tccactaagt cttcagcatt gatagacatt tcaaattgca acggatcaac
     1441 taatgcacgt ttacgcttac gcatttctgc taactgctta gcgagtgctt cttctcgttc
     1501 tgcgacaaca tctttgctag ctacttcttc agcttctaac aattcaaagg ttacttcagt
     1561 ttcctctgtc atgttatcga ccattttttg agcaacttct ggtgtctttg caattagatg
     1621 agcaggacga caaagttcat ggcgttcggt atgccataaa aaatctaata atagtagatt
     1681 ttctttcccc ggcgctaatc gtgtgccacg accaaccatt tgactataaa gagctcttac
     1741 ttttgtgggt ctcagtacaa ctacgcaatc gactgtcggg caatcccacc cctccgttaa
     1801 aagcattgaa ttgcatagta cattatattt atcattatca aagtcttcta ggacttcagc
     1861 gcggtctttc gattccccat tgacctctgc tgctttaaat cctttttggt ttagaatatc
     1921 acgaaatttt tgggaagttt taacaagcgg aagaaataca actgttttac ggtttgcgca
     1981 ttgcttcacc atttcatcgg caatttgttc taggtacggg tcaagcgccg tcccaatctc
     2041 acttgcttta aaatctccag cttgctgact aactgtagat aagtccaaag tcaacgggat
     2101 agtaactgcg gtaattttag ataagtaacc agacttgatg gcatctacta aggaatattc
     2161 ataagctaaa ctatcgaaat acttacctag attttgtttg tcaccgcgat ctggtgtcgc
     2221 tgtcactccc aaaacattgc tactatcaaa gtgttgcaaa actctttggt aaccatcaga
     2281 gatggcatga tgggcttcat caataataat tgtgtcaaaa tgatttgtag gaaacttact
     2341 caaacgcttc tctctctgca tcgtttgaac tgatccaact acaaccctga accatgaccc
     2401 taaagaagta ttctctgctt tttctaatgc tgtccctaat ccagttgctg tcatcaattt
     2461 atcactagcc tgttctaaaa gttcggacct atgagccaga accaaaactc tctctccgag
     2521 ccttacacgg tcttcgataa ttttcgaaaa gacaatagtt ttaccgcaac cagttggaag
     2581 gacaagaaga gttctcttct tgccgtcttc ccactcgtgt tgcactgctg accttgcctc
     2641 ttcttggtaa ggtctaagct gcattagaat cctccccatc cgccttgagg ttgttgaggt
     2701 gtttgcattt gaccttgttg atatgactgc gttgctggtt gttgtgcaaa attagtgcct
     2761 tgtgcctgtt gtccctgata tgtaggttga gcagattgtt gatgtgtcat ttgctgtggt
     2821 tgtgcgacat ctttatttaa tacttttgtc caatcaactt catcagcgta aatcatagat
     2881 ttgatgttat cgtattcgcg atcagcataa tcgccggtgc ctttacgttt attaatacga
     2941 gcaaccccct tagctccgat gacggtattc cagttcattt taagtggttc cccatgtttc
     3001 ttttgaccaa tagctccaaa gaaagctgat agcatacctt ctgttgtagt atgtaggaat
     3061 aagttatgag ttaattgcgc gattccttct gatgtttcta tttgaatcgt aacgaccgcc
     3121 ttgttacacg ctggtaattt tcctggactc ttcggattag gtgtgtgacg agcacgctcc
     3181 atattggtta ctgtgaattg ataatcacca ggcactaatt gaacaaaacc tacactgtct
     3241 tgtgtaattt catcatccca tcccaattca cggtcaaagt tgttattgta ttcagtcatt
     3301 tttatttctc ctattttcta ttaagctaaa attgtaatgt tagtttgatc agcaagttct
     3361 tcttttaagt agttagcaat attattgata gcatctaagc gccactttcc accatctgct
     3421 tcaaacaaag ccatattagc aagttgatta atgcggaaaa tgaactcact tgaaggttgt
     3481 tctacttcag aaaatgtgcg gtatggacgt aatgtaactg ggtttggcgc cttagctttt
     3541 gcaaggcttg ccacaccttg tttaattgtg gcagtttgac caatgccatc atcaacaatt
     3601 tctgagccat tttcgatttt taatgcacta gcgaattcaa taactgtgtt acgatcgtca
     3661 gcgttaacga ataatgattg cagactaata ttaaaatcag aaggtgaatc atagcggcca
     3721 aattgaacat ttggaataat tgcctccaca gttactaaca catttcgatt aaggtcgtca
     3781 tcatcttctt cgcaaacaat aacttcacga gggccttcta caatgaccat aagacgcttg
     3841 gaattaatat tgttcatatc tgatttaaga taatcaatta aactgtcaag cgtgtttaaa
     3901 ttcaatgttt ttggataata cttagtttta agttcaacca aagaatattt gttgcgatca
     3961 taatactctt taccatcact acccaagata gtcttaggtt tttcgtgagc tgtatttact
     4021 gcatattcca aagcttcttt aatgttttct gtcatgttag tttcctactt tcttttgctt
     4081 attaaaatca ataacatctt cattaatacc tttttcaagg tgatcaattg gttcaccgat
     4141 gtcagttctt agcactgcct catcgtcaaa ataagtttga ccaggcatcg cgcttttgag
     4201 ctcgttagca taaaccttac catctttttg accaacaagg accgttgtag ccacgcctgt
     4261 ctgtggtgct agcgttgact taacttccat agctgttgaa acagtttgac gggcatcgtc
     4321 tggtttcata gttaacgtaa tagttacttt acgggctact tttgtttctg tattaggatc
     4381 taagatattg tcaaagactt tttccaattc cttgtctact ttttcttgta agccaccttc
     4441 tccgatggca gacaagtcta atttgattgt tttattcatt gtttgttata cctcgctata
     4501 atttctaatt cccaaaacct atgcgccttc cacagtaaag ggtggctcga cagtacgcac
     4561 ttgcgtttta atcacttcta acgtagctaa ccaattggcc acaatcatat tccaataatc
     4621 tgacgggaag ttttcaattg gtgtcattgg cgggaagtgt cctcggatgt ttgctactgc
     4681 cacaagctca tcaggagtga cctgctctgc cgacatcaag tcagtcaatg cttttggcat
     4741 acttggtggg taggctaccg gcgcagatgt cggttgcata ggtggttgtt ctggtgcttt
     4801 ttcagcttgc tcatgtacgg attcatgtgc ggtttgtgat gcaggagttt cctgtactgg
     4861 tggcgtttgt ggcactggtt gagttggtac ttgtgcgaat agatgtgcga ttactgcata
     4921 gtcaagaggc atttcgtctg gtaacccatg acggtttttt gcatcccacg ctgggtgatg
     4981 ttgcgtgtat agcacacgtt gaccaccagt tgcctttttc ttttttgatt cgctagtcat
     5041 aactactgtt ttgtagttgg caaacaagac catatcagcc cattctttga ccaagggggc
     5101 agtctgtgag cttgtctttt taccaagttt caactcccaa cggtcataag ctcccatctc
     5161 gtcaggttgt tcaaattttc tcatttgtgc atgggcagtt aatacaatat tgataccgag
     5221 ttcaatcagt tcttggagca tattcaagaa tcgacctact tcctcttttg tgtaggtata
     5281 accattgccc caaccaaagt cctcgatacc tttcttgcca tgttgagcac agacatcatc
     5341 tactattaag ctttctgccc aatcgattgt gtcaatgacc agtgtcttgc aacatgttgg
     5401 attcgcttta atccatgcaa tttgattttt tagcatagtg tagcttgttg gtttatccat
     5461 acgggccaca tccatattgt ctgttgatcc ctccgtatca atgaacaatg gttcaggaaa
     5521 attagcagca aaactagatt taccgattcc ttctggtcca taaatgatga cacgttgagc
     5581 acgtgctcgt ttacctcttg taatttgcat atttacctct ctttctaaaa ctcacctttc
     5641 caagtcggtg ctactgtttc agcaaaatta ccaccctctg ctgttttaaa gttatgagct
     5701 ttgttttcca ctgagtatcc atcttctata atgatggcac actcttcacc aattgataca
     5761 cgggttgcaa tagcttgcaa accctcctgc tctagccgtt taccaaattg ttcaagtgtg
     5821 atattgtcca tctgttcgag tttatcaatc aaaacaaagc cacaatctgg ttttagttta
     5881 cgtacaatag cagttgctac tattagttgt tggctgcctg acatgttatc ccactcttga
     5941 ccaaggtaaa gtaactttcc atcatctact gataagcctt caagcggcaa atctgcatta
     6001 atcaataagt ctcttttttg ttgacgaatt gactcaatat cattagtcaa tatgttatat
     6061 tgttcacgct gctgtttagc atcttcttca gctttatctt tatcaaagtt agcgcgcact
     6121 ttgcggttga cttcatcaat atcggcaata ttcgcctcga tttcagctgt tgattcatca
     6181 tgtaaatcca tagcgtcagt atttgctatt tttaaatcct cgcttaactt attcgtctta
     6241 gcttctgcat ctgctaataa cttgcgtaaa cggtcaactt ccaagataga ttgattataa
     6301 tcatagcgaa tacgttctac attttgacgc ttttgagcat tctctccgtt tttggctaag
     6361 atagcttggt gttgttggat aagctcagaa atacttacca gttgtttagg tgcgtcagga
     6421 taatatgtca tctccttagc aaacttttct ttttggtctg ctataacacc gatagcgtga
     6481 cgttgattgt atatttcttt ttcttttagc tctaactctg ctagctgatc accgacacca
     6541 ataatttcaa gcaagacatc tgctttctct tttggtgtac tatccataaa tttcggcaag
     6601 ttaatagcca attcttctac aaagctatct agcaactgct gaccgccttt ttggccgttt
     6661 ggatcaatta ctttaagact ggcatttttg cctttccgtt caacaataag tccatttgac
     6721 atggtaattt taagcgtagg tggcacttgc gatccttcgc gcatagcttg actaggcttg
     6781 tatttattac cgcctagtgc ccaagcaata gcatctaata cgcttgtttt gccttggtta
     6841 ttattaccac cgataatggt caagcctgtt gcagatggtt caatctttac cgctttaata
     6901 cgcttaacgt tttcgatttc aagtttgttt attgttattg acattataat tctcccttgt
     6961 tccatgcttt taacagggct atttgatcaa tttcatccaa ttcagcaatg catttatcta
     7021 gcgtactttt caagataaaa tcactagcaa taatgacatc taataaattt gctttagctg
     7081 taactacaaa gtaatgttcc gccaattcat tatttaacct gcgattttcg tctcgcaaaa
     7141 attcgttgtc gttaattagt tgttgtttca tacttttttt ctcatataag cgtggaatgc
     7201 atcatactgc ttttcagatg acaatcgctt agtatcgtgt ttaatcggtt cctgtttttt
     7261 tggttttgta aaaataaaat ctaatagttt catgttatac tcctagttct aataaaattt
     7321 gatagtaacc tgcaaaagaa attggcactg ttatattttc tggctcacat tgtgaaccat
     7381 cttttcgaaa acagtgaact tttggggtcc attgctcttt tttgtttttc atggtaaaat
     7441 tgcctcataa gaatctgtct gtcccgtaaa ctgctatttt acagggcttt tttatttgca
     7501 tcatcgttcc attacgggaa cgtctttatc aaaaaaaatt gctatttttt cgattggtaa
     7561 tccaaaaatc aaagtaattt ttgcaagctc atcagctcca attgaaacaa taccgttctc
     7621 tctttttgca tatggtgttc gtgttttcca ccccatagat tgtgcaactt cacattgtgt
     7681 cataccgcta gcaattcgct cggcttttag tcgcttcaaa ttgattgtca tatacatact
     7741 ccttttttta tttttgttcc cgttttggaa cacctttatt ataaaaccta cgttccaaat
     7801 tgtcaacgat tttttctaaa aaaaatacgt ttatttgttt tttagcgttt tattgtattt
     7861 ttttgggaac gatggtataa tgatattact aaataacatt aaggataaca aaacatgaga
     7921 acaaacagcg aaattatttc tttgatacag agcaaagtag aagaaagaaa gatgtcaatg
     7981 agtgagttgg ctagaaatgt tggtattgca aaatcaacga tgtctagata ttttaataaa
     8041 acaagagaat ttcctttaaa cagggcagat gattttgcta aagcacttaa tatatcaaca
     8101 gagtttttac ttggtattga tttaaatagc gaagtagatg gttcggaact gcttggaata
     8161 taccgcgaat tagaagaaca acgaagagta attgttttag atacagcaaa agagcaattg
     8221 gaagaacaaa caaaaatcat caatttcagt gataaaaaaa ctgatatcga agatattttt
     8281 gaagttaaag gaacgacttt tgctgcagca gcaagcggat ttggtagagg ttttgaagca
     8341 gatgactatg atacttatac agtttataca gacgaagaac ctccacatta tgattatgct
     8401 attggcataa gaggcgatag catgttacca aagtacgagc aaggagatat gctttatatc
     8461 gttgataaag gaatgtcaac atacagcgga caattatgta ttgttgtaca taacgggaac
     8521 acttatttta aaaaagttta cactgaacat gatggacttc gattagtatc acttaataaa
     8581 aaatatagcg atatttttat tggctatcca ccagcagaag atacatacat taaaatatat
     8641 gacgttgttg gtagttttac accgattgaa ttttaactaa tgtttttaga gaggacaatg
     8701 atatgacgtt aaaacaactt ttaaaatcaa aaaatctggg agaatatttt gaagcaaaaa
     8761 acaatgcaga aaagatgaat gagattgaaa accgtggctt aaagcaagta atgaaaaact
     8821 cagtacgaca gacccaatta aatagcgaaa taaaacaagt gataaaaaaa gaaaaagagg
     8881 cggtaagatg tccaaaatgt aaaagtacta atgttggatt tatgcagcaa ggtaaaaaga
     8941 cattttctgt taaaaaggcc gtcgcaggaa ctcttttaat aggtggaaca gttatgggat
     9001 ttttaggaga aaaagggaag aagcaatggc actgtaacga gtgcagctgt atatttgaga
     9061 caaaataaaa aaagccccac gctctcaaag tttggcgact ctgagcgtga ggcgaatcta
     9121 gtatagtaaa aacctgcttt aagtaggtct ctttactgta ctcattttaa caaaaaatga
     9181 ggtaaaaaac aatgagaaaa gtagctattt actctagagt atcaacaata aatcaagccg
     9241 aagaaggata ttccattcaa ggacagattg aagctttaac aaagtattgt gaggcaatgg
     9301 aatggaaaat ttacaaaaac tactctgatg caggtttttc aggcggtaaa cttgaacgac
     9361 cggcaataac agaattgatt gaagacggta aaaacaataa atttgatact attttagtct
     9421 ataaactaga caggctatca agaaatgtaa aagacacact ttacttagtc aaagatgtat
     9481 ttactgctaa caatatccat tttgtcagct taaaagaaaa tatcgacact tcttcagcaa
     9541 tgggaaatct ctttctcact ctcttgtcag ctattgcaga gtttgaaaga gaacagatta
     9601 aagagcgaat gcagtttggt gttatgaata gagcaaaatc tggaaaaaca acggcttgga
     9661 aaacaccacc ttatggatat agatacaaca aagacgaaaa aacattgtcg gtcaacgagt
     9721 tagaggctgc taatgtcagg cagatgtttg acatgataat ctctggctgc tcaatcatgt
     9781 caattacaaa ttacgcgaga gacaatttcg tcgggaatac gtggacacat gtaaaagtaa
     9841 aaagaatatt agaaaacgaa acatataaag gattagtgaa gtatagggaa caaactttct
     9901 caggtgatca tcaagccatt atcgacgaaa aaacatataa taaagcgcaa atagctttag
     9961 cacataggac agatacgaaa acaaatacta gaccttttca agggaaatat atgctttctc
    10021 acatagcaaa atgcggttat tgtggtgccc ctttaaaagt atgcacagga agagctaaga
    10081 acgatggtac gagaaggcaa acttacgttt gtgttaataa aacagaaagt ttggctagac
    10141 gaagtgttaa taattataat aaccaaaaga tttgtaacac tggtcgatat gaaaaaaaac
    10201 acatcgaaaa atatgttatt gatgttcttt ataaacttca acacgataaa gaatatctta
    10261 aaaaaataa
//
LOCUS       DAUGOH010000047        10096 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUGOH010000047 DAUGOH010000000
VERSION     DAUGOH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10096
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.047"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            163..3189
                     /locus_tag="VH957_001478"
     CDS             163..3189
                     /locus_tag="VH957_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEQ8559378.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQINSGSQLEQSKESLSLNKRVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTLGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            3209..3610
                     /locus_tag="VH957_001479"
     CDS             3209..3610
                     /locus_tag="VH957_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEQ8559379.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGTYYEAAKKWAQGRMG
                     VPKAVGIIHIERIFNLQSGANAGKEINSESN"
     gene            complement(3790..4665)
                     /locus_tag="VH957_001480"
     CDS             complement(3790..4665)
                     /locus_tag="VH957_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEQ8559380.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYRTLHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIEVN"
     gene            4801..5322
                     /locus_tag="VH957_001481"
     CDS             4801..5322
                     /locus_tag="VH957_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8559381.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIR"
     gene            5537..6055
                     /gene="rimM"
                     /locus_tag="VH957_001482"
     CDS             5537..6055
                     /gene="rimM"
                     /locus_tag="VH957_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEQ8559382.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DRFVQEVTIVSHRKQKHFDIIKFKDMYHINAIEKYKGYTLKVSKANQGDLQEGEFYYH
                     QIIGMAVYEKGRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            6045..6776
                     /gene="trmD"
                     /locus_tag="VH957_001483"
     CDS             6045..6776
                     /gene="trmD"
                     /locus_tag="VH957_001483"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEQ8559383.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALGQGED"
     gene            6776..7768
                     /locus_tag="VH957_001484"
     CDS             6776..7768
                     /locus_tag="VH957_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8559384.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGAELTENLIKQLSRFEDHTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEMLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            7946..9004
                     /locus_tag="VH957_001485"
     CDS             7946..9004
                     /locus_tag="VH957_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEQ8559385.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFED"
     gene            9017..9940
                     /locus_tag="VH957_001486"
     CDS             9017..9940
                     /locus_tag="VH957_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEQ8559386.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     VVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDEGHQV
                     ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
BASE COUNT         3377 a         1600 c         2045 g         3074 t
ORIGIN      
        1 gagaaattac cttaaaacag gaagtactag agtatttaaa ataagtgata gacttggata
       61 ttattaggtc gactagtgtc cttttcaata atttaatatc gttattatta gtatcagcca
      121 atcaaatgtg gataagttgg cttttagaaa ggttttacca caatgaagaa acatcttaaa
      181 acagttgcct tgaccctcac tacagtatcg gtagtcaccc acaatcagga agtttttagt
      241 ttagtcaaag agccgattct taaacaaact caagcttctt catcgatttc tggcgctgac
      301 tacgcagaaa gtagcggtaa aagcaagtta aagattaatg aaacttctgg ccctgttgat
      361 gatacagtta ctgacttatt ttcggataaa cgtactactc ctgaaaaaat aaaagataat
      421 cttgctaaag gtccgagaga acaagagtta aaggcagtaa cagagaatac agaatcagaa
      481 aagcagatca attctggatc tcaactagaa caatcaaaag agtctctttc tttaaataaa
      541 agagtgccat caacgtctaa ttgggagatt tgtgatttta ttactaaggg gaataccctt
      601 gttggtcttt caaaatcagg tgttgaaaag ttatctcaaa ctgatcatct cgtattgcct
      661 agtcaagcag cagatggaac tcaattgata caagtagcta gctttgcttt tactccagat
      721 aaaaagacgg caattgcaga atataccagt agggctggag aaaatgggga aataagccaa
      781 ctagatgtgg atggaaaaga aattattaac gaaggtgagg tttttaattc ttatctacta
      841 aagaaggtaa caatcccaac tggttataaa catattggtc aagatgcttt tgtggacaat
      901 aagaatattg ctgaggttaa tcttcctgaa agcctcgaga ctatttctga ctatgctttt
      961 gctcacctag ctttgaaaca gatcgatttg ccagataatt taaaagcgat tggagaatta
     1021 gctttttttg ataatcaaat tacaggtaaa ctttctttgc cacgtcagtt aatgcgatta
     1081 gcagaacgtg cttttaaatc aaaccatatc aaaacaattg agtttagagg aaatagtcta
     1141 aaagtgatag gggaagctag ttttcaagat aatgatctga gtcaactaat gctacctgac
     1201 ggtcttgaaa aaatagaatc agaagctttt acaggaaatc caggagatga tcactacaat
     1261 aaccgtgttg ttttgtggac aaaatctgga aaaaatcctt atggtcttgc tactgaaaat
     1321 acctatgtta atcctgataa gtcactatgg caggaaagtc ctgagattga ttatactaaa
     1381 tggttagagg aagattttac ctatcaaaaa aatagtgtta caggtttttc aaataaaggc
     1441 ttacaaaaag taaaacgtaa taaaaactta gaaattccaa aacagcacaa tggtgttact
     1501 attactgaaa ttggtgataa tgcttttcgc aatgttgatt ttcaaaataa aactttacgt
     1561 aaatatgatt tggaagaagt aaagcttccc tcaactattc ggaaaatagg tgcttttgct
     1621 tttcaatcta ataacttgaa atcttttgaa gcaagtgacg atttagaaga gattaaagag
     1681 ggagccttta tgaataatcg tattgaaacc ttggaattaa aagataaatt agttactatt
     1741 ggtgatgcgg ctttccatat taatcatatt tatgccattg ttcttccaga atctgtacaa
     1801 gaaatagggc gttcagcatt tcggcaaaat ggtgcaaata atcttatttt tatgggaagt
     1861 aaggttaaga ccttaggcga gatggcattt ttatcaaata gacttgaaca tctggatctt
     1921 tctgagcaaa aacagttaac agagattcct gttcaagcct tttcagataa tgccttgaaa
     1981 gaagtattat taccagcatc actgaaaacg attcgagaag aagccttcaa aaagaatcat
     2041 ttaaaacaac tggaagtggc atctgccttg tcccatattg cttttaatgc tttagatgat
     2101 aatgatggtg atgaacaatt tgacaataaa gtggttgtta aaacgcatca taattcctac
     2161 gcactagcag atggtgagca ttttatcgtt gatccagata agttatcttc tacaatggta
     2221 gacctcgaaa agattttaaa actaatcgaa ggtttagatt attctacatt acgtcagact
     2281 actcaaactc agtttagaga catgactact gcaggtaaag cgttattgtc aaaatctaac
     2341 ctccgacaag gagaaaaaca aaaattcctt caagaagcac aatttttcct tggccgcgtt
     2401 gatttggata aagccatagc taaagctgag aaggctttag tgaccaagaa ggcaacaaag
     2461 aatggtcagt tgcttgaaag aagtattaac aaagcggtat tagcttataa taatagcgct
     2521 attaaaaaag ctaatgttaa gcgcttggaa aaagagttag acttgctaac aggattagtt
     2581 gagggaaaag gaccattagc gcaagctaca atggtacaag gagtttattt attaaagacg
     2641 cctttgccat tgccagagta ttatatcgga ttgaacgttt attttgacaa gtctggaaaa
     2701 ttgatttatg cacttgatat gagtgatact attggcgagg gacaaaaaga cgcttatggt
     2761 aatcctatat taaatgttga cgaggataat gaaggttatc atgccttggc agttgccact
     2821 ttagctgatt atgaggggct cgacatcaaa acaattttaa atagtaagct tagtcaatta
     2881 acatctattc gtcaggtacc gactgcagcc tatcatagag ccggtatttt ccaagctatc
     2941 caaaatgcag cggcagaagc agagcagtta ttgcctaaac caggtacgca ctctgagaaa
     3001 tcaagctcaa gtgaatctgc taactctaaa gatagaggat tgcaatcaaa cccaaaaacg
     3061 aatagaggac gacactctgc aatattgcct aggacagggt caaaaggcag ctttgtctat
     3121 ggaatcttag gttacactag cgttgcttta ctgtcactaa taactgctat aaaaaagaaa
     3181 aaatattaaa ttgatttaag gagaagaaat gataacacaa gaaatgaaag atcttattaa
     3241 taaccaatta gcaatggttg cgacggttga tgccaaaggt caacccaata ttggtccaaa
     3301 acgttctatg cgtctctggg atgataaaac atttatttat aatgaaaata cagatggtca
     3361 aactcgtatt aacattgaag ataatgggaa aattgaaatt gcctttgttg atcgtgagcg
     3421 ccttttaggt tacaggtttg taggaactgc tgaaattcaa acagaaggta cttattacga
     3481 agcagcgaaa aaatgggcac aaggacgcat gggggtacca aaagcagttg gtattattca
     3541 tatcgagcgt atttttaatt tacaatctgg tgctaatgca ggtaaagaaa taaacagtga
     3601 aagtaactaa aattaactgt aacagtattt aggaccctta ttttaaacgc taaaaaacaa
     3661 gcatactctt ttttacagca tagtgactat gttgtaaaaa ggggtatgct tattaggtgc
     3721 tcttaatatt tctagataac tgcacctaat aagttttcaa tagacttata gcacattaat
     3781 tgacttcaat tagttgactt caatactaga aagagaagaa cagtgatgtt ggtgttcgtt
     3841 taaagaagta tcgatttcca cagtgactga gtttatattg tacctttgac aaatcagtct
     3901 aatagatttt ttgcaatgtt tttcagtggt agattctctc aagcagcaat gtatagttgc
     3961 tctatgatca ataccatcca tcgaccaaac attaagctga ttaacagaca ctatatgagg
     4021 aagttggctg agttcatggt gcaaagtgcg atagtctatc gaatcaggaa caccatctaa
     4081 aaaaatgtta gcagttgcta ctaactttgg aagagcttta gataatataa aagaagcaat
     4141 ggcaattgat aataaaggat caagaatgta ccaaggtttc cattttaaga tcagtgacaa
     4201 tatgataatg gctaaccacc caaggatatc ttctaaaaag tgaaggctta atatttcttc
     4261 attttttgtc tggttagagt gaatgatgaa gctagcaaat ccattgatta taattgcaaa
     4321 aatagctaaa acgaacatac cgtcataatt aacaatagta ggatgccata attttggtat
     4381 cgtttcaatc attactaata atgacccgct aataagtatt agatttgttg ttagtgctcc
     4441 taaaaggcta aatcgcttat agcctagtga aaaatttgga ctctcttttt taacagcctt
     4501 tctttctaag atagctgaga taccaatagc aatggcatct ccaaaatcgt ggacagcatc
     4561 tgctaaaata gcacccgaaa agaataatgt cccaaaaata aattcaatga gggaaaaact
     4621 aagatttaat ataaaaataa tggtgacttt tttacttgct ggcataattt tctccttttg
     4681 ttatactggt aatatgtata gtagaattct ttattctatt atctaagagt taaaatacaa
     4741 ttactataac caaaaatgag cacctgttca atagtgaaca acatttagaa agtgtccgat
     4801 atgacaaaag acagacaaat caaaaaaaca aaaacagcta tctatagtgc ttttattgct
     4861 ttattacaaa aaaaagaata ttcgaaaata actgttcgag atatgattac acttgctaat
     4921 gtagggagat caacctttta tgcacattat gaaagcaaag aaatgttact aaaagaactc
     4981 tgtgaagaac tttttcatca tttgtttagg caaaaaagaa atgtgacttt tgaggactat
     5041 ttggtacata ttttaaagca ttttgaacaa aataaagaca gcattgcgac gttgttactt
     5101 tctaatgatc cctatttttt attaagattt aaaaacgaac tagaacatga tgtttaccct
     5161 aacttgcgct gcaagtatat cgacaaaacg actattccag aagtattcct gaaacaattt
     5221 gttctatcta gttttataga aaccttaaaa tggtggctcc atcaaaggca aaggatgtct
     5281 gcaaatgaac tattaaagta ttatttagag ctcataagat aatgactagt gagtcatctt
     5341 gccaaattca attttttaat acagacggat tttaacaatt taacagagaa agacaaaact
     5401 gtaagtgcaa aatagactat aacgtgataa aataataggt aatttggttc tgaaaaagaa
     5461 gtgtctatca aactttagaa tcaagagagg tcgctaaagt gacgtgagat aaagagttaa
     5521 cgatttagga gctaccatgg aatattttaa tgttggaaaa attgtcaaca cgcaaggcct
     5581 gcaaggagag atgcgcgtgt tgtctgtcag tgattttgct gaggaacgct ttaaaaaagg
     5641 ctcacaatta gctttatttg atgataaaga tcggtttgtt caagaagtga caattgttag
     5701 tcaccgtaaa caaaagcatt ttgatattat caaatttaaa gacatgtatc atattaatgc
     5761 gattgaaaaa tataagggct atacgttaaa agtgtcaaaa gctaatcaag gagacctgca
     5821 agaaggagaa ttttactacc atcagattat cggtatggct gtttatgaaa agggccggtt
     5881 gattggctat gtcaaggaaa tcttgcagcc aggtgctaat gatgtttggg tagtgaaacg
     5941 ccaaggaaaa cgagacttgc tcttaccata tattccccca gtagttctta atgtagatgt
     6001 tcctaacaag cgcgtggatg ttgaattgat ggaaggctta gacgatgaag attgatattt
     6061 taaccctttt tcctgaaatg tttgcccccc tagaacattc cattgtaggc aaagcaaaag
     6121 aaaaaggatt acttgacatt cactaccata actttcgaga ttatgctgaa aaagctcgtc
     6181 atgtggatga cgaaccctat ggtgggggcc aaggcatgtt attgagagca cagcccattt
     6241 ttgacaccat tgaacagatt gaagccaaaa aaccaaggat tattctttta gatccagcag
     6301 gtaaaccctt tactcaggct tatgctgaag aattagctct tgaggaagag ttaattttta
     6361 tttgtggtca ttatgaaggt tatgatgagc ggattaagac cttggtgacg gatgaaattt
     6421 cattaggtga ctttgtatta acaggaggtg agttggcggc catgactatg gtggatgcga
     6481 ccgtcaggtt aattccacag gtacttggga aagaaagtag ccatcaggac gattcttttt
     6541 catcaggact tttagaatac cctcaataca caagacctta tgattatcgt ggtatgacag
     6601 ttccagatgt tctaatgagt ggtcatcacg aacgtattcg cttgtggcgt ctagaagaaa
     6661 gtctcagaaa aacctatttg agaaggccag atttgttaga gcggtacgat ttttccgagg
     6721 aagagcgcaa gctattggat aagattaaag aagcattggg tcaaggagaa gattagtgaa
     6781 agataaagca tatgatatta cgattattgg tggtggtcca ataggtttat ttgcagcctt
     6841 ttatgcaggt cttaggggcg taacagtaaa gattattgag agtttgtcag aacttggtgg
     6901 acagcctgcc attctttatc ctgagaaaat gatttatgat attccagctt atccatcttt
     6961 aacaggtgct gagttgacag agaatttaat aaaacaatta agccgttttg aagatcatac
     7021 aaccatttgt ttaaaagaag aagtattaac ctttgacaag gttaaaggtg gtttttcgat
     7081 taggactaat aaggcagagc atttttcaaa agccattatc attgcttgtg gaaatggcgc
     7141 ttttgcacca agaactttag ggttagaaag tgaggaaaac tttgctgatc ataacctttt
     7201 ttataatgtt caccagttgg accagtttgc gggacaaaaa gttgtgattt gtggtggtgg
     7261 agattcagca gttgattggg ctttggcttt agaagatatt gctgagagtg tgacggttgt
     7321 gcaccgtcgt gatgctttca gagcacatga acacagtgtg gaattattga aagcatcaac
     7381 ggtcaacctc ttaacacctt atgtgccaaa agcattgaaa ggaattggaa acctggctga
     7441 aaaattagtt attcaaaaag tgaaagaaga tgaaatgtta gaacttgaat tggacagtct
     7501 tattgttagt tttggttttt caacttctaa taagaatttg aaaaattgga atctcgacta
     7561 taagcgttca agtattactg tttcaccact ttttcaaaca agtcaagaag gtatttttgc
     7621 cattggtgat gcagccgctt ataatgggaa agtggatttg attgctactg gttttggcga
     7681 agcaccaaca gcagttaatc aggccattaa ctatatttat ccagatcgag ataaccgtgt
     7741 ggtgcattca acctctttaa ttgactaagg gagtcggaag tttcaagagc agtagcaaca
     7801 gctaatattc agtttgtcag gagaggacaa atggttttta cctaagtctt cgtgacaagt
     7861 tttatacttt gtgataaaat agtcattgtg aaaaaagtgt gatggttttc acagattaac
     7921 acattacaat gaaaaggggt ctatcatgac aacaacagat aaagagacat ttagttcttt
     7981 tatgaataag gtcttggctg gtacagcgat tgctatcgtt gtggcactca ttccaaatgc
     8041 tattttagcg actttcttaa aaccgctttt gccaaacatg gcagctgctg aatttttaca
     8101 cattgtgcaa gtcttccaat tcttcacgcc gattatggct ggtttcttga ttgggcaaca
     8161 atttaagttt aatcctatgc aacagttggc tgttggtgga gctgcttata tcggttctgg
     8221 ggcttgggct tatacagaag tcattcaaaa aggtgtggcg acaggaacat tccaacttag
     8281 aggtattggg gacttaatca atatgatgat tacagctagc cttgcggttt tagctgtgaa
     8341 atattttggg aataaatttg gctctttaac cattatcttg ttacctatca ctataggaac
     8401 tggcgtaggt tatattggtt ggaaattttt gccttatgtg tcttacgtga caaccctgat
     8461 cggacaaggt attaattctt ttacaacctt acaacctatt ttaatgtcta ttttaattgc
     8521 agttgctttc tcgcttatca ttgttagtcc gatttcaact gttgcaatcg gtttagctat
     8581 tgggcttaat ggaatggctg cgggagcagc ttctatggga attgcatcga cagcagcagt
     8641 cttagtgtgg gcgacgctta aagttaataa atctggtgta ccaattgcta tcgcacttgg
     8701 ggctatgaaa atgatgatgc caaacttctt gaaacatcct atcatggcta ttccgatggt
     8761 gttcactgca gcaattagct cattaacagt accattgttt aatcttgttg gaacaccagc
     8821 ttcatctggt tttggcttag ttggtgcagt aggtccgatt gcttctttag caggtggtag
     8881 ctcaatactt attattatcc ttgcttggat cattgttccg tttgcggttg cttttgcggc
     8941 gcataaggtt tctaaagata ttctaaaact ttataaagaa gacattttcg tctttgaaga
     9001 ctaataggag gaaaatatgt tagtttatat tgctggctca ggagccatgg ggtgccgttt
     9061 tggttaccaa atttcaaaaa caaataacga tgtgattttg ttagataact gggaagatca
     9121 tatcaatgcc attaaagaaa acggtttagt ggtgacaggg gatgtggaag aaacagttaa
     9181 gcttcctatt atgaaaccga ctgaagccac tcaagaagcc gatttgatta tcttgtttac
     9241 aaaagcaatg cagttgccac aaatgcttca agacattaaa ggcattattg gaaaagaaac
     9301 caaagtgctt tgccttttaa atggtcttgg acacgaagac gttattcgtc agtacattcc
     9361 agagcacaac attttgatgg gggtcactgt ctggactgct ggtctagaag gaccaggtcg
     9421 tgctcatctt caaggagttg gtgctcttaa cttacaaagt atggatccaa acaatcaaga
     9481 tgagggacat caagtagctg acttgctaaa taaagctaac ttaaatgcga cttatgatga
     9541 gaatgttgtg ccaaacatct ggcgaaaagc ttgcgtgaat ggtaccatga attcgacttg
     9601 tgctctttta gattgtacga ttggcgaatt atttgccagt gaagatggtc tcaaaatggt
     9661 aaaagaaatc atccatgagt ttgttatcgt tggtcaagca gaaggtgtcg aactaaacga
     9721 agaagaaatc acgcaatatg taatggatac atctgttaaa gctgctcacc attacccatc
     9781 aatgcaccaa gaccttgtgc aaaatcaccg attgactgaa attgatttta tcaatggtgc
     9841 agtcaatacc aaaggtgaaa agcttggtat caatactcca tactgccgta tgattacaga
     9901 actagttcac gctaaagaag cagtgttgaa catccaataa acgctatcaa atcgttatac
     9961 tcaatattat ggctaaagct ttaatattga gttttttgtt atgctgatag tatttttctt
    10021 aggcgtcatt atttgtgagc ctagattatg agttaataaa agaaataata attggtagaa
    10081 tttgatagat tttgaa
//
LOCUS       DAUGOH010000048        10090 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUGOH010000048 DAUGOH010000000
VERSION     DAUGOH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10090
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.048"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(228..1001)
                     /locus_tag="VH957_001487"
     CDS             complement(228..1001)
                     /locus_tag="VH957_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8559387.1"
                     /translation="MSGSLGNKKIMASNIRRHLDKKNINPKEFSKVMGFKYSTVLDWV
                     NAKTYPRIDKIELMANYFGVEKSDLVEVYSHKSVSSPSNIVVKLDKELKEPRHSDWIK
                     HGENLLSEQNTVEDSKNTVIDLFSYNYYDHAASAGTGQYLNDVQVETIELPVDYDADF
                     VIPVYGDSMEPKYHSGDYVFVKLSIDLSDGDIGVFEYYGDAYIKQLLINAEGAFLHSL
                     NSKYDDIPIDKDSDFRIIGEVVGSYSGNHNFTSYDYNRT"
     gene            1365..1523
                     /locus_tag="VH957_001488"
     CDS             1365..1523
                     /locus_tag="VH957_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559388.1"
                     /translation="MNWKKLMLGNLEHTFTSRDGKEKTSVEFEGGVLPALLVLGGITW
                     LIAWFITK"
     gene            1557..1766
                     /locus_tag="VH957_001489"
     CDS             1557..1766
                     /locus_tag="VH957_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559389.1"
                     /translation="MEGIEKVHDRRGRPDSLKVEQVIHLSILRGEGTGYDKVRMVEQY
                     YDMDGNLIFELDPCSEGYQEFLGLR"
     gene            complement(1742..2200)
                     /locus_tag="VH957_001490"
     CDS             complement(1742..2200)
                     /locus_tag="VH957_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEQ8559390.1"
                     /translation="MNFNPISLAKSYPNYIPLTIREDYEEAHAILNLSPKASATLSRR
                     CLQGMIRDFWQVSKRSLSDEIEAINDLVDPSTRKVLDALRKIGNIGAHPEKDINLIVD
                     IEPLEAHKLLKFIELLMQKWYIERHDNETLLQDILDMDTNKQSQRKPKNS"
     gene            2487..2702
                     /locus_tag="VH957_001491"
     CDS             2487..2702
                     /locus_tag="VH957_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8559391.1"
                     /translation="MTKMTLKMLRVSKNWNQETAAKKLRISVSKLSNWENAKTFPDAI
                     EINKIEKLYDVNYSDIIFLPTKHGLTV"
     gene            complement(2794..3303)
                     /locus_tag="VH957_001492"
     CDS             complement(2794..3303)
                     /locus_tag="VH957_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559392.1"
                     /translation="MELFNTIIGVIALIIAVIALVHSIYYNMVKIKLSDCYISRVDKG
                     YDWMYDFSISNLSNVSVTIKKIELYNKDGKLISDNGFNPFQKYEADMQNEADDYYGLS
                     MPNYYMPLDYQWESSPFKSDTEVYPSSRENFSYYLDEKPVKIKITTDKRIHKFRKYQL
                     FFPHFDNNS"
     gene            3358..3876
                     /locus_tag="VH957_001493"
     CDS             3358..3876
                     /locus_tag="VH957_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3102 domain-containing protein"
                     /protein_id="HEQ8559393.1"
                     /translation="MNEITLSDNLQQIELEISHHKQIAGQSIWEIGRRLKHVKEQNLT
                     HGQFGNWVESIGIAKTEASRFIKIAEEIPNLGTYTNLGTKALYLIATLPDDQKQEQLE
                     RIENGDNPTVRELQEIKRENNHIKHTEAEKATSYLKSLSYGLFTPFETRETPKQKEII
                     ELENKNNGDDAA"
     gene            3895..4140
                     /locus_tag="VH957_001494"
     CDS             3895..4140
                     /locus_tag="VH957_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559394.1"
                     /translation="MKELESKINELEEMVINMDEVAVVIPWKVAKNLLQRADYLSEEE
                     RRLLQWKFGDSPYQGKRSEKVRNLLEGLRDSGSSDNS"
     gene            complement(4099..4308)
                     /locus_tag="VH957_001495"
                     /pseudo
     CDS             complement(4099..4308)
                     /locus_tag="VH957_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090780.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4365..4682
                     /locus_tag="VH957_001496"
     CDS             4365..4682
                     /locus_tag="VH957_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559395.1"
                     /translation="MRPKRYPYQKNKLIIQSKNAKTKIELDSGKITINAEEIKVGDLA
                     NEISKVQLAKEKVSETIGQDKKPTETVDFRISRLEKEVEILKEHLKNTRSLAQCAYNL
                     TSR"
     gene            complement(4661..4882)
                     /locus_tag="VH957_001497"
     CDS             complement(4661..4882)
                     /locus_tag="VH957_001497"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559396.1"
                     /translation="MSKLSPKPTRKKLDRSWKSLDSFLQNVLSDPLFDFALVDLKLYD
                     MDKQDILSELNLIGYDVTDKNNGYLEVRL"
     gene            5051..5236
                     /locus_tag="VH957_001498"
     CDS             5051..5236
                     /locus_tag="VH957_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8559397.1"
                     /translation="MWEKIEQLMIERNLNMNKLAKLTGIHKSHFSDLKSGRIKHLSWP
                     NMVKLSTGLKVSLDEFR"
     gene            5310..5540
                     /locus_tag="VH957_001499"
     CDS             5310..5540
                     /locus_tag="VH957_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559398.1"
                     /translation="MLAKLKSGIEVPYEELWMNDNDLAEFIGKSFDQTQRLLRKMYKD
                     RNYRKYIDKVGGRSTKVKKFEEWRKTQNEKLI"
     gene            5524..5664
                     /locus_tag="VH957_001500"
     CDS             5524..5664
                     /locus_tag="VH957_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559399.1"
                     /translation="MKSLFNFIFAKPKKEEKPKWTIETHGWEANARRYNQLHGLPGKQ
                     VW"
     gene            5674..5892
                     /locus_tag="VH957_001501"
     CDS             5674..5892
                     /locus_tag="VH957_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559400.1"
                     /translation="MEQHLINDNEFLRDENRRLNNELAEHYFVVTAKANLLDVIIASG
                     FILQSTIDKCIAELDEIDQMELRKVWNK"
     gene            5894..6136
                     /locus_tag="VH957_001502"
     CDS             5894..6136
                     /locus_tag="VH957_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559401.1"
                     /translation="MRLAKQKIGAQQNGYGRIGCDIEIYNEIAEIADKCGYTLTSLTN
                     ALLGYALENSELTAETKTVEVFKFTIGNEDFDNGNN"
     gene            6120..7439
                     /locus_tag="VH957_001503"
     CDS             6120..7439
                     /locus_tag="VH957_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8559402.1"
                     /translation="MMVTINKLEIENVKRIKAVKIEPSATGLTIVGGNNNQGKTSVLD
                     AIAWALGGNKYKPSQATREGSMVPPTLKITMSNGLTVERKGKNASLKVVDPNGQKGGQ
                     QLLDSFVEELAINLPKFMDGTPKEKADVLLEIIGVGDQLAELEFKEKEIYNQRHAIGV
                     IADQKEKFAKEMTYYPDAPKQLVSISELIQQQQAILAKNGENAQKRQNVERIRYDYDQ
                     SILEVDRLRKLLADAEAKTNKLSEDLKIANTDAMDLHDESTAEIEANIADIDEVNRKV
                     RANFDKDKAEEDAKQQRDQYNTLTNEIEVIRQQKRDLLTNADLPLEGLTVDDGKLLYL
                     GQEWDNMSGSQQLMVATAIVRKLKPECDFVLIDKLEQMDNITLTQFGQWLEQEGLQAI
                     ATRVSTGEECAIIIEDGYSVENKAHNFETAAAGSFAETVAPAWQGGF"
     gene            7454..8536
                     /locus_tag="VH957_001504"
     CDS             7454..8536
                     /locus_tag="VH957_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8559403.1"
                     /translation="MQITRGKRARAQRVVIYGPEGIGKSSFAAQFPEPLFIDTEGSTD
                     NMDVARMDKPTSYTMLKNQIAWIKANPTCCKTLVLDTIDWAESLIVDDVCAQHGKKGI
                     EDFGWGNGYTYTKEEVGRFLNSLQELIEFGINVVLTAHAQMRKFEQPDEMGAYDRWEL
                     KLGKKTSSQTAPLVKEWADMVLFANYKTVVMTTDTNKKKATGGSRVLYTQHHPAWDAK
                     NRHGLPEEMPLDYAGIAHIFAQQAPSQPVAETPSTQQPTPTQSAHEPAHKQPTQPPVA
                     NESQAPLPDTLPQAMKDLMVPDQVTADELVQVANIRGHFPLGTPIENFPPNYWDMIVA
                     NWSATLEVIKTQVRVEPDLPFTVEGT"
     gene            8731..9324
                     /locus_tag="VH957_001505"
     CDS             8731..9324
                     /locus_tag="VH957_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559404.1"
                     /translation="MTEYNNNFDHELGWDDEITQDSVGFVQLVPGDYQFTVTNMERGR
                     HTPDPQNPGKLPACNKAVVTIQIETSEGIAQLTHNLFLYTTTEGMLSAFFGAIGQKKH
                     GEPLKMNWNTVVGAKGVCRVNKRKGTGKYADQEYDNIKSMIYADEVDWSKVLNASQPT
                     QNTYQQPQQPTQQQPQPQQGSFFQGNTTQPQGGWGGF"
     gene            9324..>10090
                     /locus_tag="VH957_001506"
     CDS             9324..>10090
                     /locus_tag="VH957_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ8559405.1"
                     /translation="MQLRPYQEEARSAVQKEWEEGRKRTLLVLPTGCGKTIVFSKIIE
                     DRVRLGERVLVLAHRSELLEQASDKLMTATGLGTALEKAENTSLGSWFRVVVGSVQTM
                     QREKRLSKFPANHFDTIIIDEAHHAISDGYQRVLQHFDSSNVLGVTATPDRGDKQNLG
                     KYFDSLAYEYSLVDAIKSGYLSKITAVTIPLSLDLTTVSQQAGDFKASDIGTALDPYL
                     EQITDEMVKQCANRKTVVFLPLVKTSQKFRDILNQKG"
BASE COUNT         3520 a         1756 c         2021 g         2793 t
ORIGIN      
        1 agtagataca attctgcttt ttcttgattt tcaattgtta agccccgatc cctcaatatt
       61 tggatctgtt cggtaattga tttgaattct ttcaaaaaga aaacctcctc cattataaaa
      121 tgaagaaggt ttcctccgta ctggtccccg tagagatacc agcgcttatt tttagtatct
      181 tcattttata ttatattatt attcttgtca acaaattata ttcattctta cgttctatta
      241 taatcgtagc tggtgaagtt atgatttccc gaataacttc cgacgacttc gccgataatc
      301 ctaaagtcac tatctttatc tatcggtata tcgtcatact tgctgttcaa gctatgcaga
      361 aatgccccct cagcgtttat aagcaactgt ttgatataag cgtcaccgta atattcaaac
      421 acgcctatat caccgtctga gaggtctatg gacagcttga caaatacata gtccccagaa
      481 tggtacttag gctccataga atcaccgtag actgggataa caaaatcagc gtcatagtcg
      541 actggtaatt caatcgtttc tacttgtaca tcatttagat actgacctgt cccagcagaa
      601 gcagcgtggt cgtagtagtt gtaagagaat aggtcgatta ctgtgttctt actatcttct
      661 actgtgtttt gttcagacaa aagattttcc ccgtgtttta tccaatcgct gtgacgaggt
      721 tctttgagct ccttgtctaa tttaacgacg atattggatg gagaagaaac gctcttgtga
      781 gaatacacct ctactaaatc agatttttcc accccgaaat aattagccat taattcaatt
      841 ttgtcaatcc ttggataagt cttagcgttc acccagtcta atactgtact atatttaaaa
      901 cccattactt ttgaaaattc tttaggatta atatttttct tatctaaatg tcttcttata
      961 tttgaagcca ttattttttt attaccgagc gaaccactca taacgacacc tcatttctga
     1021 ttatattata acggaaaaac cgtgtttttg tcaaaaaata ttttaaaaaa taaaaaaaat
     1081 aacgtttttg tgttgacaac acggtttaac cgtgttaaac tataatcaag cttaagaaat
     1141 taagcaaaac aaaaggaggt gcagccgatg aaatctaggc taaacaaaaa gcctaaacac
     1201 aaagagctag aagtcgaaat caagattctt tggtttaagc ttagaataaa atatctgatt
     1261 actaggtaat cggataaggg gggtgaaact cccccgcccc gtttaggggt aagtttagtt
     1321 tagcacattg gctgtatctc cgcaagaatg aaaggagagg ttgcatgaat tggaaaaagc
     1381 taatgcttgg caacttagaa cacacgttta ctagtcgtga tggcaaggaa aaaacaagcg
     1441 ttgaatttga aggcggtgta ttaccagctc tgttagtgct aggtggtatc acttggctga
     1501 ttgcttggtt tattacaaaa taaaaactcc caagagggag tggaaaggag gaggaaatgg
     1561 aaggaataga aaaagtccac gatagacgtg gacggccgga ttctttgaaa gttgaacaag
     1621 ttattcactt gtcgatttta agaggggaag ggacaggata cgataaggtt cgaatggtgg
     1681 aacaatacta tgatatggat ggtaatctca tttttgaatt agatccgtgc tcagaagggt
     1741 atcaagaatt tttgggctta cgttgagatt gtttgttagt atccatatct aaaatatctt
     1801 gaagtagtgt ctcattatcg tggcgttcga tgtaccattt ttgcattagg agttctataa
     1861 attttagcaa tttatgagct tctaacggtt caatatcaac aattaagttg atgtcttttt
     1921 caggatgtgc tccaatattt ccgatttttc gcagtgcatc taggactttc cgtgtactcg
     1981 ggtctactaa gtcatttata gcttcgattt catcagatag actacgtttt gatacttgcc
     2041 aaaaatctct aatcattcct tgtagacaac gtcttgaaag ggttgcagag gcttttggac
     2101 ttaggttaag aatagcatgg gcctcttcat agtcctctct gattgtcaga gggatgtagt
     2161 tgggataaga ttttgctagc gaaatagggt tgaagttcat tatacgattt cggaactgtc
     2221 tgcccttgcc aataatatcg atagagacat ttcgacaatt aggacaatcc acaagctgga
     2281 tagttatttc gtcacgcttg tggaaatttt catcatccga agggacaaat tgagggcggc
     2341 cttttgaaaa attcagattt tcttctcgga aggtatcgta atgttttggt acaggacaac
     2401 cgcagaaaag acaaaataaa tgttcagaat ccatgatttt ctccaatcat tttatttaaa
     2461 ttataccata gaaagggggt gggagaatga cgaaaatgac gttaaaaatg cttagagttt
     2521 cgaagaactg gaaccaagaa acagcagcta aaaaactaag gatttcagtt tcgaaattaa
     2581 gcaattggga aaatgcaaaa acatttccgg atgctattga aataaataaa attgaaaaac
     2641 tatacgatgt caattactct gatattattt ttttaccaac aaaacacggt ttaaccgtgt
     2701 aacgaataaa ctaacacaaa actagaaagg ataaaagaaa aaatgctact aacagcagca
     2761 cttattttga ttttactaac gaacatcgct atcttaacta ttattgtcaa aatggggaaa
     2821 gaataactga tattttcgga atttatgaat acgcttatca gttgtgattt tgattttaac
     2881 tggtttttca tctaaatagt aagagaaatt ttctcgacta gatggatata cttcagtatc
     2941 tgacttaaat ggcgatgact cccattggta atctaatggc atataataat tcggcattga
     3001 taatccataa taatcatcag cttcattctg catgtcagct tcgtattttt gaaagggatt
     3061 gaagccatta tcgcttatta gttttccatc tttgttgtaa agttcaattt ttttaatagt
     3121 gactgaaaca ttcgataagt tactgatact aaaatcatac atccaatcgt aacctttatc
     3181 tactcttgaa atgtaacaat cagataattt tattttaacc atgttgtagt agatagagtg
     3241 aacaagagcg atcacagcaa taattagcgc gatgacgccg ataattgtat taaataattc
     3301 catttttatt cttccaatcg tttttatttt aattatacca aattagaaag gatagaaatg
     3361 aatgaaataa cactatcaga taacttgcaa cagatagaac ttgaaatcag tcatcataag
     3421 cagattgcag gacagtccat ttgggagatt ggcagaagat taaagcatgt gaaggagcaa
     3481 aatctcactc atggacagtt tggaaactgg gtagagagta ttggaattgc aaagacagaa
     3541 gctagtcgtt tcatcaaaat cgcagaagaa atcccaaatt tgggaacgta cacaaatttg
     3601 ggaactaaag ccctctacct catcgccacc cttccagatg accaaaagca agaacaactt
     3661 gaacgaattg aaaatggcga caatcctaca gttcgagagt tgcaagaaat caaacgtgaa
     3721 aacaaccata tcaaacatac agaagcagaa aaagctacca gttatttaaa atcactatct
     3781 tatggtttat tcacaccatt tgaaactcgt gaaacaccaa aacaaaaaga gattatcgaa
     3841 ctggaaaata aaaataacgg tgatgatgcc gcttagaact agaaaggaga acgcatgaaa
     3901 gaattagaaa gcaaaatcaa tgaactcgaa gaaatggtaa tcaacatgga tgaagtggct
     3961 gtagtgattc catggaaagt agcaaaaaac ctactacaaa gagcagatta tttgtcagaa
     4021 gaggaacgca gattgttgca gtggaaattt ggagattccc cctaccaagg caaacgttcc
     4081 gaaaaagtcc gcaacttgct agagggactt agggatagtg gaagttccga taatagctga
     4141 taattttaat tctgttgttt ggtcattgtg cataaaaata agagtttcat ttttacgatt
     4201 aggctcaatt caatgatcaa tcacaaagtc tccgacaaga ctatgtaaga taacagtttc
     4261 aaaatcatca atactattta atagaggagt taattcttct aaagtcattt agttaccctc
     4321 cttcctaata ggataactac attatacaac tagaaaggaa acacatgaga ccaaaacgtt
     4381 atccatatca aaaaaataaa ttaattatcc agtcgaaaaa cgcaaagaca aaaattgaat
     4441 tagatagcgg aaaaataact atcaatgctg aagaaatcaa ggttggtgat ttagcaaacg
     4501 aaatttcaaa agtgcaacta gccaaagaaa aagtatctga aactattggt caagataaaa
     4561 agcctactga aacagtagac tttaggattt ccagacttga aaaagaggtc gaaattttaa
     4621 aagaacactt aaaaaataca cgttcattag cgcagtgtgc ttataaccta acttctagat
     4681 agccattatt tttgtctgta acatcataac cgattaagtt gagttcagat aaaatatctt
     4741 gtttatccat gtcgtaaagc tttaaatcaa ccaaagcaaa atcaaataat ggatcagata
     4801 agacattttg taaaaaacta tctaaagatt tccatgacct atctagtttt ttacgagtcg
     4861 gcttaggact caatttactc ataaccttcc cccttccttg ttagatttaa ccaataagaa
     4921 aagctagttt gagaggccag cgagagatct tgtttgttat gagtatatta tatcagaaag
     4981 gaacgaaaaa cacaacatat agttgtgaat attaaacaaa acacaacatg ttgacttttc
     5041 aatatagatt atgtgggaaa aaatcgaaca attgatgatt gagaggaatc tcaatatgaa
     5101 caaattagca aaattgacag ggattcacaa aagccacttt agcgatttga aaagtggaag
     5161 aataaaacat ctgtcatggc cgaacatggt caagctatct acaggattaa aagtcagctt
     5221 agacgaattt agataacaaa aaagtccgac ggcaatcgga ctcaaatcaa attttaattt
     5281 acttagatta taccatgaaa ggaaacgata tgctagcgaa attaaaaagc ggtattgaag
     5341 taccttatga agaactatgg atgaatgata atgatttagc tgaatttatt ggaaagtcat
     5401 ttgatcaaac gcagcgatta ctaagaaaga tgtacaaaga cagaaattac cgtaagtaca
     5461 ttgacaaggt tggtggtcgt tcgacaaaag ttaaaaaatt tgaagaatgg agaaaaacac
     5521 aaaatgaaaa gcttatttaa ctttattttc gcaaaaccta aaaaagaaga aaaaccaaaa
     5581 tggacaattg agacacacgg ctgggaagct aatgcacgta gatataacca gttgcatggc
     5641 ttacctggta agcaggtttg gtaggaggga agaatggaac aacacctaat taatgataac
     5701 gaatttttgc gagacgaaaa tcgcaggtta aataatgaat tggcggaaca ttattttgtg
     5761 gttacagcta aagccaattt attagatgtc attattgcca gtggttttat cctgcaaagt
     5821 acgatagata aatgtatagc cgaattggac gaaattgatc aaatggaact tagaaaggta
     5881 tggaataaat agtatgagat tagcaaagca aaaaattgga gctcaacaaa atggatatgg
     5941 tcgcatcgga tgtgatattg aaatttataa tgaaattgct gaaattgcag ataaatgtgg
     6001 atatacccta acgagcttaa caaatgctct tttaggttat gctttagaga atagcgagct
     6061 cacagcagaa acaaaaacag ttgaagtttt taaatttact ataggaaacg aggatttcga
     6121 taatggtaac aattaataaa ttggaaattg aaaacgttaa gcgtattaaa gcggtaaaga
     6181 ttgagccgtc ggcaactggc ttgactattg ttggtggaaa caataaccaa gggaaaacaa
     6241 gcgttctaga cgcaattgct tgggcactag gcggcaataa atacaaacct agccaagcaa
     6301 cgcgagaagg gtctatggtg ccgcctacgc ttaaaatcac catgtctaat ggacttactg
     6361 ttgaacggaa aggtaaaaat gccagtctta aagtcgttga tccaaacggc caaaaaggcg
     6421 gacaacaatt actagatagc tttgttgaag agttagctat taacttacca aagtttatgg
     6481 atggaacacc aaaagagaaa gcagatgtct tgcttgaaat tattggtgtc ggtgatcaat
     6541 tagctgaatt agaattcaaa gaaaaagaaa tctataatca acgtcatgct atcggtgtta
     6601 tagcggacca aaaagaaaag tttgctaagg agatgacata ttatcctgac gcacctaaac
     6661 aactggtaag tatttctgag cttatccaac aacaacaagc tatcttagcc aagaacggag
     6721 agaatgctca aaagcgtcaa aatgtagaac gtatccgcta tgattatgat caatctatct
     6781 tggaagttga ccgcttacgc aagttattag cagatgcaga agctaagacg aataagttaa
     6841 gcgaggattt aaaaatagca aatactgacg ctatggattt acatgatgaa tcaacagcag
     6901 aaatcgaggc aaatatcgcc gatatcgacg aagtcaaccg taaagttcgc gctaactttg
     6961 ataaagataa ggcagaggaa gacgctaagc agcaacgtga tcagtacaac acattgacta
     7021 atgagattga ggttattcgc cagcagaaac gagatttatt gactaatgca gacttgccac
     7081 ttgaggggct taccgttgat gatggcaaac tgctgtatct tggccaggag tgggacaaca
     7141 tgtcaggaag tcaacaactt atggtagcca ctgccattgt acgaaaactt aaaccagagt
     7201 gtgacttcgt tttgattgat aaactcgaac aaatggataa catcacactt acacagtttg
     7261 gccaatggct agagcaagaa ggattgcaag ctatcgcaac cagagtttca accggtgaag
     7321 agtgcgcgat aattatcgag gacggctact ccgtggaaaa taaggctcat aattttgaaa
     7381 ctgcagcagc aggtagtttt gccgaaacag tagcacccgc ttggcaaggt ggattttaga
     7441 aaggagaata tcaatgcaaa tcacaagagg aaaacgtgca cgggctcaac gtgtggtcat
     7501 ctatggtcct gaagggattg gtaagtctag ctttgctgct caattcccag agcctctgtt
     7561 tattgacact gagggatcaa cagacaatat ggatgtggcc cgtatggata aaccaacaag
     7621 ctacactatg ctaaaaaatc aaattgcatg gattaaagcg aatccaactt gttgcaagac
     7681 acttgtcctt gacacaattg actgggcaga aagcctaatc gttgatgatg tgtgtgctca
     7741 acacggtaaa aagggaattg aagattttgg ctggggtaat ggttatacct acaccaaaga
     7801 agaggttgga cgcttcctaa acagtctgca agaactgatt gaatttggta tcaatgtcgt
     7861 ccttactgcc catgcccaaa tgcgtaaatt tgaacaacct gacgagatgg gagcttatga
     7921 ccgttgggaa ttgaaacttg gtaaaaagac aagctcacag actgctccgc tcgtcaagga
     7981 atgggctgat atggtactct ttgctaatta taaaactgtt gttatgacaa ctgatactaa
     8041 caaaaaaaag gctactggcg ggtctcgtgt tttgtacacg caacaccacc cggcgtggga
     8101 tgctaagaac cgtcacgggt taccagaaga aatgccactc gattatgctg gtattgctca
     8161 tatctttgct cagcaagcac caagtcagcc agtagcagaa acgccatcaa cacaacaacc
     8221 gacgcctact caatccgcac acgaacccgc acataagcaa ccgacacaac cgccggtagc
     8281 aaatgaatcg caggcaccac tgcccgacac attaccacaa gctatgaaag atttgatggt
     8341 acctgatcaa gttacagcgg atgaactagt acaagtggct aacatacgcg gacatttccc
     8401 gcttgggacg ccgattgaaa acttcccccc caattattgg gatatgattg ttgcaaattg
     8461 gtcagcaact cttgaagtta tcaaaacaca agtaagagtc gaaccagact taccctttac
     8521 cgtggaaggg acttagattt tgggaaatag aaataatagc gaggtataac aaaaatggat
     8581 aaaacaatca aatttgactt atctgccatt ggtgatggtg gaaagtggcg cttagatgct
     8641 atcaataata ttgctaacta cttaaaagaa gaacttgctg atcaaactaa cattacaatt
     8701 ttagcttaat agaaaatagg agaaataaaa atgactgaat acaataacaa cttcgaccat
     8761 gaattgggat gggatgatga aattacacaa gacagtgtag gttttgtcca attagtgcct
     8821 ggtgattatc aatttacagt aactaatatg gagcgtggtc gtcacacacc tgatccgcag
     8881 aatccaggaa aattaccagc gtgtaacaag gcggtcgtta cgattcaaat tgaaacatca
     8941 gaaggaatcg cgcaattaac tcataactta ttcctatata ctacaacaga aggtatgcta
     9001 tcagctttct ttggtgctat tggtcaaaag aaacatgggg aaccacttaa aatgaattgg
     9061 aatactgtcg ttggtgcaaa aggtgtctgt cgtgtaaata agcgaaaagg aactggtaaa
     9121 tatgctgatc aagaatacga taacatcaaa tctatgattt atgcagatga agttgattgg
     9181 tcgaaagttt tgaacgctag tcaaccaaca caaaatactt atcaacaacc gcaacaacca
     9241 actcagcaac aacctcaacc gcaacaggga agtttcttcc aaggtaatac aacacaacca
     9301 caaggtggat ggggaggatt ctgatgcaat taaggccgta tcaggaagag gcacggtcag
     9361 ccgtacaaaa ggaatgggag gaaggtagaa aacgaactct actagtcctc cctaccggtt
     9421 gcggtaaaac tattgtcttt tcgaaaatta tcgaagaccg tgtaaggctc ggagagagag
     9481 ttttggttct agctcatagg tctgaacttt tagaacaggc tagtgataaa ttgatgacag
     9541 caactggatt agggacagca ttagaaaaag cagagaatac ttctttgggg tcatggttca
     9601 gggttgtagt tggatcagtt caaacgatgc agagagagaa gcgtttgagt aagtttcctg
     9661 caaatcattt tgacacaatt attattgatg aagcccatca tgccatctct gatggttacc
     9721 aaagagtttt gcaacatttt gatagtagca atgttttggg agttacagcg acaccagatc
     9781 gtggtgacaa acaaaatcta ggtaaatatt tcgatagttt agcttatgaa tattctttgg
     9841 tagatgccat caaatctggt tatctatcaa aaatcactgc tgttacaatt ccactatcac
     9901 tggacttaac gactgttagt cagcaagcag gagactttaa agctagtgac atcggaactg
     9961 ccttagatcc atatcttgag cagattaccg atgaaatggt gaagcaatgt gcaaaccgta
    10021 aaacagttgt atttcttcca cttgttaaaa cttcccaaaa attccgtgat attctaaacc
    10081 aaaaaggatt
//
LOCUS       DAUGOH010000049         9015 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUGOH010000049 DAUGOH010000000
VERSION     DAUGOH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9015
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.049"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(112..1254)
                     /locus_tag="VH957_001507"
     CDS             complement(112..1254)
                     /locus_tag="VH957_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEQ8559406.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFCQTTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
     gene            1535..4513
                     /locus_tag="VH957_001508"
     CDS             1535..4513
                     /locus_tag="VH957_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEQ8559407.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDSQTTSAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLEHLNVV
                     FVVDECHRAVTPERQRHLTNTFRNSRWYGFTGTPIFMENKRAQLGDLAQTTERQYGKC
                     LHQYTVKEAIHDKSVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLNSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFLEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAYQAFDKLYASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            4526..5758
                     /locus_tag="VH957_001509"
     CDS             4526..5758
                     /locus_tag="VH957_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8559408.1"
                     /translation="MTKSKQPQYRFDGFEGEWEEKRISDIANVFTGGGTPSTQNDQYW
                     TGNIPWIQSSDLSKDEILDVNPKKFITKLGLSNSAAKLIPKNSIAIVTRVGVGKLSII
                     NREYTTSQDFLSISDLKENLKFTVYSLYRLLQKELNQLQGTSIKGITKGYLLSKTILI
                     PSLPEQGAIGELFQMVDQLIQLQDQKLATLKEQKQTFLRKMFPAQGQKVPEIRLQGFK
                     GEWEEKKLGEVSTHRSGTAIEKYFDSEGEFKVISIGSYGTNNLYVDQNIRAVSNELTN
                     SKLVASGELTMVLNDKTANGAIIGRCLLITENNKYVVNQRTEIIRPDINISSYYLFHY
                     LNGEFRNGIIKIAQGGTQIYVNYSSVEQLKINIPTLKEQEAIGNFFQTLDQQIAQSEE
                     KLTELKALKQTLLNRLFV"
     gene            5771..7351
                     /locus_tag="VH957_001510"
     CDS             5771..7351
                     /locus_tag="VH957_001510"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEQ8559409.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLLAVCDNLEKHFNTFTEAQKIFEDAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNFDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(7903..8508)
                     /locus_tag="VH957_001511"
     CDS             complement(7903..8508)
                     /locus_tag="VH957_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8559410.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(8489..>9015)
                     /locus_tag="VH957_001512"
     CDS             complement(8489..>9015)
                     /locus_tag="VH957_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559411.1"
                     /translation="LSLENSNITHGFIVNELNDLVSGIRDEMDTYHPIVPANQTMKEN
                     IQSLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRL
                     SLTIQSDIIIIEESNQVVEKVHSISYGRGLKSFQETLAAFDGDLELQMDTKQFTIRIL
                     LPIDWKLCYEDFIN"
BASE COUNT         3039 a         1734 c         1532 g         2710 t
ORIGIN      
        1 caaaatgttt ctgtttttca tactatgcta atgagttagc tcgtgcgtct ccttcttcat
       61 aggttacttt taaccgccaa atgaatgcta cacaatcgaa aatagatgag tttacttatt
      121 aaactgagct atcaatagca taaggttagc tgctaatatt ttgatattag aaagtgttgt
      181 tgttttatct atcgctgctt ctaaggaaat tggctgctgt tgtattgaaa aaacagccaa
      241 aaagtcttct gctgctagtc ctgtctcaat ctttacagaa ccacatagag caatcgttgg
      301 aacttgatat tttttagcca ttcttgcaat cgcaacaggt accttgccag attgtgattg
      361 tgtatccagg catccttctc cagtaataac taaatcacaa gactgaaggg aattatccag
      421 atttagtagc tctgcaatcc tgctaaaacc actagttaag gtgcctccta ataggacaat
      481 ggcacctcct aatcctccag ctgctccact tcctggtatt gtctgtaaat caatggttgt
      541 ttggcaaaaa acttttttag caaagttact tgcaatttga tcagtttctt caatttgact
      601 aaggctccca cctttttgag ggccaaagac cgcagcaaat ccttgagggc catgatatgg
      661 attggtcaca tcagtcagcc ctaatagcgt aacaggtgat gctaaagtat caagataaga
      721 tcttcctgtc atgaaatcat agtttaaact ttccaaaaac cctttgccac catcagaagt
      781 gcctgttcct cctagcatga tttcgatttg agtagctcct ttttgaatgg catctttaac
      841 tgccaaaccc aaaccatagg aagtggcttg tgcataggtt actgaattgg gggtgatctt
      901 atcaatacca ataatactcg cagattcaat aaaagcttgc tttgcgtgac gataataagc
      961 gactttaatc gggcgtctta atagatcaat ggtttttact tgatgccacc tccccgccac
     1021 ggtttgtgag agggctgcta aacttccttc tcctccatca gcgatagctc ttgtttcaat
     1081 aactaactgc ttatcgacag aaagaagggc ttgagctaca ctagtgttaa gttctggaga
     1141 cgttaccgat cccttaaaag aatctatggc taccaaaatt ttcatatctt caataaattc
     1201 cttttctgta tattgtagca gattatcgtc ctttaaaacc ctattaatag tcaagctaga
     1261 tctgtcttaa gttttttatc tattttgaga actcgacctt tttactaatg ttgtcttatt
     1321 actttcttca ccttaaatta ttgtcaagca aactcaaaaa tacaagaact ttctcgattg
     1381 catttacata gtcatagctt tgtttagttg ctaggatctt aagcattcaa ctaatcaaaa
     1441 aaagactgtt tggaaggttt caatagcttt gccattctaa aaaggatccg ccaatgatat
     1501 aatattacta tatcatgtcg aatggggatt aaaaatggga aatcaaacta aaacggaact
     1561 tgaacttgaa aaagagttga tccatctctt agaaacaggt gaaagtcaat ggacatatcg
     1621 taaagaatta aaaactgaag atgctttatg ggataatttc tttaagatct tagcgcaaaa
     1681 taacacgcaa tatctgaacg aggagccttt aacagctagt gaaaaagagc agattaagaa
     1741 tcaacttaac tttgtcaatt actatgaagc ggctaaatgg ttagctggtg aaaacggcat
     1801 tgctaaagta caagtgcaac gcgaagatgc aaaactagga acgattcgtt tagaagtcgt
     1861 taaagcagac aatgtggctg gtggaacttc tgtttatgag attgccaatc aagttgcttt
     1921 ctctggttct cgtgatagac gaggtgatgt gacacttctc atcaatggct tacctatgat
     1981 ccaaattgaa ttaaaatctc agaatcatca atgcattgaa gcttttaacc aagtcaaaaa
     2041 gtatgataaa gaaggccagt ttagaggtat cttttcaacc ttacaaatgt ttgtggtctc
     2101 aaataaaaca gatacaaggt atatcgctgc agctaaagaa aataaattaa accctaactt
     2161 cttgacccaa tgggtagatc aaaacaacaa accacaaaaa gatctctttg cctttgccaa
     2221 agaagtccta tctatccctc gtgctcacca aatggtcatg acttactctg tcattgatga
     2281 tgataaaaaa gcactaattc tccttcgtcc ttatcagatt catgcaatcg aagccgtcgc
     2341 tgaagcgagt cgtcaccgca agtctggcta tatctggcac acaacaggtt ctggaaaaac
     2401 cttaacttcc tataaagtgg ctcgcaatat ccttcaaata ccggccgttg aaaaatccat
     2461 ctttgtcatt gaccgaaagg atttagatag tcagaccact tctgcttttc aatcttatgc
     2521 gcaaaatgat atctttgatg tcgatgagac agaagatacg agacaactca tcaaaaattt
     2581 agaatccagt gatcgtcgtg ttgtggtcac caccattcaa aaactcaatg ctatgatcag
     2641 tcagatggaa agttatgaca ctccaaaatt caagaaacta aaagagcgtc ttgaacacct
     2701 aaatgttgtc tttgttgtag acgaatgcca ccgtgctgtc acgccagaac gtcaacgtca
     2761 tctcacgaat acttttcgaa acagtcgctg gtatggcttt acaggtactc ctatctttat
     2821 ggaaaataag cgtgctcaat taggtgattt agcccaaaca acggaacggc aatacggcaa
     2881 atgtctccat caatacactg tcaaagaagc cattcacgat aaatcggttc taggcttcca
     2941 agttgagtat aagacaacca ttcctgatat gcctgaagac agtattcctg aagaagctta
     3001 tgatcatgaa gaacatatgt tagctgtctt aaatagtatc attaatcaat cacgtaagaa
     3061 gcttggcttt aataatggga ttggtcagac attcgaaggc ttattaaccg ttaagagtat
     3121 tgctcgtgcc caagcctatt atgatctgat tcagaaagtc aaagctggtg aaacggattt
     3181 agtcatttct aagaaggtca aagaaaaact gccagacttt ccaaaggtag ctattactta
     3241 ttctatcact gaaaatgaca atgcgtctat cagccgacaa gataaaatga ccaaaaatct
     3301 agaagactat aatcacctct ttggcactaa ctttaccatc gataacttac aaggctataa
     3361 cagagattta aatgatcgct tagcccgtaa aaaagataaa ttcaaagacc gtcatgaaca
     3421 attagacctc gtgattgtgg ttgaccgtct cttaacgggc tttgatgcgc cttgtttatc
     3481 aaccatcttc atcgatcgcc agcctatgaa acctcagcac attattcaag ctttctcacg
     3541 aaccaaccgt atctttgaaa gtagaaaaca ttacggtcag gttgtgactt tccaaacacc
     3601 acttcgtttt aaagaagctg ttgacaaagc gcttagcctc tactctaatg ggggtgaaaa
     3661 cgacgttttg gccccttctt gggaagaaga aaaagcaaga ttccttgaaa aagtaacagt
     3721 attaaaaaat atagttcctg atccagacgc tttcccaact attgagagcg cacagacagc
     3781 ttttctcaaa caatacgcca aagcctatca agcatttgat aagctctatg catctgtaca
     3841 ggtctatagt gactttaatg aaacactgtt gagtgaggtt gggttatcag atgaagtgat
     3901 tgatacttat aaaggcactt accaaaatgt cattgcagaa atacgaaagc gaagagaaga
     3961 tgacgaagcc atcccagaaa tcaatatcga ctatgagcta gaaagtgttc agatggatga
     4021 tatcaactat cactatatct tgaccttaat tcaagccttt gtcgatcaag aacaagaagc
     4081 tcttcaagaa aggctcaatg acaatcccat ggatcaatac atccaagatt tggcaaaatc
     4141 aaaccctgct atggctgact cactagctga gttatggcaa gatatccaaa aagaacccaa
     4201 agcctatgaa gggaaaagca ttgcttatga gttggataac ctcattggtg ataaaatcca
     4261 aagggccatc aaacactttg cggaccaatg gaaggcagat cctgacaaat tagcctttgt
     4321 ggcgactaat tatcatagtg ctaactctac caaacaagtg ggcatgtcaa ccttaaaaga
     4381 atccctagac taccaagcct ataaagaaaa acaaggtgat tctgccatga ataaactcaa
     4441 atacaagagc caatttgaac gggagttagt tcaattcatt agagatcaaa tccaaccctt
     4501 aaaagggcac taggaaagga aagagatgac aaaatctaaa cagcctcaat atcgctttga
     4561 cggttttgaa ggggagtggg aagagaaacg aatttctgat attgcgaatg tgtttactgg
     4621 aggtggcaca cctagtactc aaaacgatca atactggact ggcaatatcc cctggataca
     4681 atcatctgat ttatccaaag atgaaatatt agatgtaaac cccaaaaaat ttattacaaa
     4741 attgggcctt tctaactctg ctgcaaaatt aataccaaaa aattctattg ctattgttac
     4801 acgagttggt gtaggaaaac tttcaattat caatagggaa tacacaacca gccaagattt
     4861 tttatctatc tcagatctta aagagaactt gaaatttact gtatattcgc tatatagact
     4921 cttacaaaag gaactaaatc aattacaagg aacgtcaatt aaaggtatca caaaagggta
     4981 tctcctttct aaaacgatac ttatcccctc tctccccgaa caaggagcca ttggcgaact
     5041 tttccaaatg gttgatcaat tgattcagtt gcaggatcaa aagctagcaa cccttaaaga
     5101 acaaaagcaa accttcctca ggaaaatgtt cccagctcaa ggacaaaaag tccctgaaat
     5161 ccgtttacaa ggttttaaag gagagtggga agagaagaaa ttgggggaag tatctactca
     5221 tagaagtgga acggcaattg aaaaatattt tgattcggaa ggtgaattta aagtcatttc
     5281 aataggtagt tatggaacta ataacctcta tgtagaccaa aatattagag cagtctcaaa
     5341 tgaacttact aattctaaat tagttgcctc cggtgaatta acaatggtac tcaatgataa
     5401 gacagcgaat ggggcaataa tcggaagatg tctacttatt acagaaaata ataaatacgt
     5461 tgttaatcaa agaacagaaa ttattagacc agatattaat atttcctctt actatctttt
     5521 ccattattta aatggtgaat ttcgtaatgg tatcattaaa attgctcaag gtggcactca
     5581 aatctatgta aattattcat ctgttgaaca attaaagata aatataccta cattaaaaga
     5641 acaagaagcc attggtaatt tcttccaaac tttagaccaa caaattgctc aatctgaaga
     5701 aaaactaaca gaactcaaag cactcaaaca aacattactc aatcgtttat tcgtataaga
     5761 aaggacgcac atggcagaga aaacaacttc actccggcaa gcactatggc attcggccga
     5821 ccaattacgt ggtcaaatgg atgccaatga ctataaaaac tatcttcttg gactcatctt
     5881 ttacaagcac ttatctgata aattactctt ggctgtttgt gataatctag aaaaacactt
     5941 caataccttt acagaggctc aaaaaatctt tgaagatgct tatcaagatg aaggcctaaa
     6001 agatgacctc atttctgttg ttactggtga tttaggttac tttatcgaac caacactgac
     6061 ctttgaaaaa ctcatccaag atgtttatca caatactttc caattagaat cattagctca
     6121 aggttttcgc gatattgaac aaagtggtga agactttgaa aacttatttg aagatattga
     6181 cctctactct aaaaaattag gctctactcc tcaaaaacaa aatcaaacca tttctaatgt
     6241 catgaaaaca ttaaatgaaa ttgactttga ggcagtagat ggggatactt taggcgatgc
     6301 ttatgagtac ttgattggtg aatttgccag tgagtcagga aaaaaagcag gtgagttcta
     6361 taccccacaa gctgtctctc acttgatgac tcagattgtc tttttaggtc gtgaagatca
     6421 aaaaggaatg accctctatg accctgctat gggatctgga tcactccttt taaatgctaa
     6481 gaaatatagt aaccaatccg ataccgtttc ttactatggt caagaaatca atacttctac
     6541 ttataacttg gctcgtatga acatgatgct tcatggcgtt gccatcgaaa accaacactt
     6601 aagtaacgct gataccttgg atgcagactg gccaacagat gagccaacca actttgatgg
     6661 ggtgttgatg aacccacctt attctttgaa atggtcagcg actgctggtt tcttaacaga
     6721 tccacggttt tcaagttatg gtgtattagc accaaaatca aaagctgact ttgccttttt
     6781 acttcatggt ttctatcatt taaaaaatac aggaaccatg gcgattgtct taccacatgg
     6841 agttcttttc cgtggtgctg cagaaggcaa aatccgccaa aaattactag aacaaggggc
     6901 tatcgatacc attatcggac tcccatcaaa tatcttttat aatacaagca tccctacgac
     6961 tattatcata ttaaagaaga acagaaccaa caaagatgtc ttctttatcg atgcctcaaa
     7021 agagtttgat aagggcaaaa atcaaaacac aatgacagat agccatatca aaaagatcct
     7081 tgatgcttat aagagtcgtg ataattttga taagttttca tatttagcct catttgatga
     7141 aatcattgaa aatgactata acttaaatat cccacgctat gttgatacct ttgaggaagt
     7201 cccagttaaa ccactgccag aattagctaa acagctcagt gacattgatc aagaaattgc
     7261 caaaacaaat gccaaactag atcaactcat gaaacaacta gtcggaacaa ccaaagaagc
     7321 acaagacgaa ttggatactt ttagaaacta aaagacaaaa aaacaccaca gtagatgatt
     7381 actactgtgg tgttttattt aaaattgagt agtgaacctt tattgagtac ttatcataca
     7441 agattctcct tcttcaccta taaatcaaaa tagaatcatc tcatctaact ttgtccgttt
     7501 ctttgtttta tttaaaatag ttatttgaag ttacaatgat ttctcaaacg tttagaaagc
     7561 ttaaacacgg ttaagagaaa ttttcaggac aacttttgat ccttccacaa aaaccatggt
     7621 gcgaaccata aagtagttcc aatcgttgat atataagcat atattaacgt tctgggagtt
     7681 gtgaagcttt acgagttttt ttagacctgg tttaaacaac ttttgtttga ctaaatttaa
     7741 aaagcttttc atatcaggca tttccctact ttttataaaa gcgttatctc aatcaatttc
     7801 aatcaaaaag aactcaaaaa caatgagttt aaatctgagt atttaacagg aaatccctag
     7861 caacgacaca agtaaaactt atgtcgtttg attatctgca actcagaaat ccataaaata
     7921 ccctaattgt tcggctttgt agatagcctc ttgcttatta tttaccaaaa gctttgagta
     7981 gatgtgggtc aaatgattaa atactgttct cctactaatt tgtaacgttt cctctatttc
     8041 ttttatagag aatcctttct tactcaaatt taagatagct atttcctggt cagttaaaga
     8101 ttcaacataa tcctgagatt cgatttgttc aaaatacttt tttccagaat ccactttttt
     8161 taagatagaa atgagttgtt tagggtctat atttttatct acaaaaccgt atgctcctac
     8221 tttttttgcc ctctctctat agattgattt aacatatcct gtcaacataa caactttcaa
     8281 atgaggagta gactgtatga gttcttttgc tatctccaat ccattttctt tagaaatatt
     8341 tgttaaatta atatcaagca atataatatc gtacttagac aaatcaatcg tcacatcgtt
     8401 aaaatgagaa gtaatcgtat ctatgacatc tacttcatca tactgttgga ataacagttg
     8461 gatactcttt gcaaatagtc tgtggtcatc aattaataaa atcttcataa cacaatttcc
     8521 aatctatggg aagtaatatt ctgatagtaa attgtttagt atccatttgt agttctagat
     8581 ctccatcaaa agctgctagt gtttcttgaa atgatttcaa tcctctgcca taacttatag
     8641 agtgtacttt ttccactact tgattgctct cctcaatgat aataatatca gattgaatcg
     8701 ttaaagataa acgaatgtct tttccatctc catattttat agcattgttt attagctctt
     8761 ttataaacct ataaacaata tctccatatg gggatggcac taccatatta tctgaacagt
     8821 taaaatacaa taaggtatta ctttttctac ttttaacaat atcatcaaaa agagactgta
     8881 tgttttcttt cattgtttga ttagcgggaa ctattgggtg gtaagtatcc atttcatctc
     8941 tgataccaga aactaaatca ttcaactcat taacaataaa accatgtgtt atattactat
     9001 tttctagaga aagca
//
LOCUS       DAUGOH010000050         8671 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUGOH010000050 DAUGOH010000000
VERSION     DAUGOH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8671
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.050"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            17..2029
                     /locus_tag="VH957_001513"
                     /pseudo
     CDS             17..2029
                     /locus_tag="VH957_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
     gene            complement(2111..2521)
                     /locus_tag="VH957_001514"
     CDS             complement(2111..2521)
                     /locus_tag="VH957_001514"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8559412.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLNLTGLTAQICQHELDHLEGILI"
     gene            3236..3313
                     /locus_tag="VH957_001515"
                     /pseudo
     CDS             3236..3313
                     /locus_tag="VH957_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3411..5288)
                     /locus_tag="VH957_001516"
     CDS             complement(3411..5288)
                     /locus_tag="VH957_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8559413.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRIGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKISVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGNYSDYLDEKAFEKETVEADLAKAIVTEEMPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(5285..6493)
                     /locus_tag="VH957_001517"
     CDS             complement(5285..6493)
                     /locus_tag="VH957_001517"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEQ8559414.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDH
                     IEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            complement(6618..7466)
                     /locus_tag="VH957_001518"
     CDS             complement(6618..7466)
                     /locus_tag="VH957_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8559415.1"
                     /translation="MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDRTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            complement(7466..7846)
                     /locus_tag="VH957_001519"
     CDS             complement(7466..7846)
                     /locus_tag="VH957_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEQ8559416.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            complement(8092..8249)
                     /locus_tag="VH957_001520"
                     /pseudo
     CDS             complement(8092..8249)
                     /locus_tag="VH957_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
BASE COUNT         2727 a         1779 c         1386 g         2779 t
ORIGIN      
        1 cttattagga gattttatga aaaaatattt tattttaaaa agtagtgtat tgagtatcct
       61 gactagtttt actctattag ttacagacgt tcaagcagat caagttgatg tgtaattcct
      121 tggcgtcaat gattttcacg gcgctcttga taataccgga acagcttaca caccaagtgg
      181 taaaatacca aatgctggga cggctgctca attaggtgct tatatggatg acgctgagat
      241 agatttcaag caagcaaatc aagacggaac aagtatacgt gttcaagctg gagatatggt
      301 cggagccagt cctgctaact ctgcactttt acaagatgag cctactgtga aagtctttaa
      361 caaaatgaaa tttgaatatg gcactcttgg taatcatgaa tttgacgaag gactagatga
      421 atttaaccgt atcatgacag gtcaagcgcc tgatcctgaa tcaacaatta atgatatcac
      481 caaacaatat gagcacgaag cttcgcatca aaccatcgtc atcgctaatg tcattgataa
      541 aaaaaccaat gatatcccct atggttggaa accttatgct ataaaagaca tagccattaa
      601 tgacaaaatc gttaagattg gcttcattgg tgttgtgact acagagattc caaatctcgt
      661 tttaaagcaa aactatgaac actatcaatt tttagatgta gctgaaacca ttgccaaata
      721 tgctaaagaa ctgcaagaac aacatgttca tgctattgtg gttttagctc atattcctgc
      781 aacaagtaaa gatggtgttg ttgatcatga aatggctacg gttatggaaa aagtgaacca
      841 aatctatccc gaacatagta ttgatattat ttttgcagga cataatcatc aatacactaa
      901 tggaactatc ggtaaaacac gtatcgttca agccctctct caaggaaaag cttatgcaga
      961 tgtccgtggt acgctagata ctgataccaa tgattttatt aaaactccat cagcaaatgt
     1021 tgttgctgta gcaccaggta tcaaaacaga aaattcagat atcaaagcta taataaatca
     1081 tgctaatgat attgttaaaa cagttactga acgaaaaatc ggaactgcaa ctaattcttc
     1141 aactatttct aaaacagaaa atattgataa agaatcccct gtcggtaact tagtaacaac
     1201 ggctcagctt actattgcta agaaaacttt tccaactgtt gactttgcta tgaccaataa
     1261 tggtggtatt cgaagtgacc tagttgtcaa aaattaccgg accatcacct ggggagctgc
     1321 acaggctgta caaccatttg gtaatatcct tcaagtcatt aaaatgactg gtcaacacat
     1381 ttacgatgtc ctaaatcagc aatacgatga aaaccagacc tattttcttc aaatgtcagg
     1441 tttaacatac acttatacag ataatgatcc taagaactct gataccccct tcaagatagt
     1501 taaggtttat aaagacaatg gtgaagaaat taacttaaca actacttaca ccgttgttgt
     1561 caacgacttt ctttacggtg gcggtgatgg cttttcagca tttaaaaaag ctaaattagt
     1621 cggagctatt aacacagata ctgaagcttt catcacatat atcacaaatt tacaagcatc
     1681 aggtaaaact gttaatgcta ctatcaaagg ggttaaaaat tatgtaactt caaaccttga
     1741 aagatcaaca aaaattaata gtgctggcaa acacagtatc attagtaagg tttttagaaa
     1801 tcgtgatggc aatatagtgt ctagtgaagt catttcagac cttttgactt ctactgaaaa
     1861 cactaataac agctttggca aaaaagagac aacaacaaac aaaaatacta tctctaattc
     1921 cactcttcca ataacagggg acaattataa aatgtctcct attatgacaa tccttgcctt
     1981 gataagctta ggtgggctaa acgctttcat taaaaaaaga aaatcctagc gtttactagt
     2041 aattgatcat ccttatataa tcaggcattt tcgccaaaaa aacctaaagt gtcctactct
     2101 aggttttttg ttaaattaaa ataccttcta gatgatctaa ttcgtgctgg catatttgag
     2161 cagttaggcc tgttaagttt aaacgctttg gtcgccaatt atggtccaaa tactcaacag
     2221 taatcttatc ataccgctgt gttttgcgat agccagataa tgacaaacaa gattctttag
     2281 tttggtaaat tcccttttta gaaaccatca caggattaaa catcaccaaa tcaataaatc
     2341 ccatactcac aataacaatg cgcttttgtt caccaatcat attggcagcc atcccaagac
     2401 attcctgtct ataaaaagct aaggtatctt gtaaatcttg gccaatccat agatcttctt
     2461 tcttggcgac ttgcgctttt tgctgtaata aaaaatgatc tgttatgatt tctctaatca
     2521 ttcttatctc cttaaacctt ctttttaatt cataaactac atgttcaatg gactattatc
     2581 accatatgat agacttagta tcatctgttt aaaacatcag gtgattcctt atttcaagat
     2641 atcttgggca actttatgaa attctgcaat atgagtacca aataaaaatt gacctgcatc
     2701 agcagattgt tgctaagttc tcatcacaat attatcgaat ttactgtctg cttcttcaaa
     2761 tgtctaagag agatagttat tgctttgtga gattttcaaa ccagatactg ctttctcttg
     2821 catttacagc cttgataggt ccaaacaaaa cacctgctgt ttgaaatgct ttaatagctg
     2881 atatgttgtt aatagttagt attataaatt ttctgaatat ttctgtcaag tttttcagtt
     2941 gacttaactt ttttacttga tttttcctca cgtaataata gaaaagaagc gccataatgt
     3001 aaactacacc ccaaacgtta gataaaaaat ctaacgtttg gggtgttttt gtatgacatt
     3061 aagctatgaa gataagctag acatttagcg cttaaaaact gagggaactc cgtttgaaag
     3121 aagcatctct gcaaagaaga agacaaaaaa ccattataaa gaatggacaa agacgagttc
     3181 tgattagatt ttcttttaag aacggctaaa ttgactcgtt ctacctacta ttatcatcga
     3241 ttattgcaac aataaacgta tcaaaataaa acgaaaagaa cttagtcctc tacaatacag
     3301 aactaaatcc tttacttcaa atagagtagc caacttttgg ggctcagtgc aagagcactt
     3361 cttttctatt atcacttgtt tattataaac ataacattac catagtatac ttatatgtct
     3421 agtccactca aatactcaaa ccgttcatac gccaataata aatcattatt gcgctgatcg
     3481 agttcctttt gtaattgagc taactggcca taatcactaa ctacagttaa catttggttt
     3541 tcaatttctt caatattagc ctcaatagtt gctattttat cttctatctg agcccattct
     3601 tgtttttcaa ggtaggacat gcgctttttc tcctctttcg gaggaagtgg catttcttca
     3661 gtgactattg ctttagctaa gtcagcctca actgtttctt tttcaaaagc tttttcatca
     3721 aggtaatcac tgtaattccc ataaaaaata cgaatatcgc cttcttcaaa ggctaaaatc
     3781 ttagtggcta ctttgtctag gaaataacga tcgtgactaa ccgtaatgac tggtcctgca
     3841 aagttagcta aaaagttttc taagaccgtc aaggtggcaa tgtctaaatc atttgttggc
     3901 tcatcaagga gaagaacatt tggcttttca atgagcagtt ttagcaagta gagccgtttt
     3961 ttctccccac cagataattt agcaatcagc gtgccatgac ttgatctcgg aaaaagaaat
     4021 tgctctaaaa gctcactgat actcgttgtt cccacgctta ttttaacctc atcagccact
     4081 tcttgaaggt aattaatgac ccgtttggtc tcatccatat ctttgagctg ctgagagaaa
     4141 taacctacac gaatagtatc tccaatatca agcttcccag aagttggttt gagatcaccg
     4201 ttgatgatat ttaacagggt agattttccg acgccgttat ctccaacaat tccaatacga
     4261 tctttatttt gaataatcaa gttaaaatcc ttaatcaact gtcggtcgcc ataagcaaaa
     4321 gaaaggtctt caaagtgaat caccttcttc ccaattcggc tcgtttcgaa agccatctcc
     4381 aatttatctg cagaactgtc ttggtgaact tcttttttca agtcagtgaa acgattgatt
     4441 ctagcctgct gtttggttgc acgcgcctgt ggctgcgtcc tcatccaagc taattcttgt
     4501 ttatagagtt gcttcttctt gtgtaaatta gtagcatctc gttcgtcttg ttctgctttt
     4561 aagcgcacat agtcttggta attgccttga tattctgtca gtcccgcttt atccaattca
     4621 aaaatacggg tagccacatg atcaaggaaa taacggtcat gggtaataaa aaggacggtt
     4681 tttttagctg tcttgagata ggttgttaac caagcgatgg tgtcaatatc gagatggttg
     4741 gtcggctcat ccaacaagag taagtcagca gctcctagca atacttgagc taactggaca
     4801 cgtcttctca taccacctga taggtctccc actttttgtt ccaaatccgt gatgcctaat
     4861 tttgatagga ctgttttgac atcactttca atagaccaag catctaagcg atccatttca
     4921 gacatgaggg actctaaggt ctcttgttta tcttcagtat aattcgccat caatagttca
     4981 tactgacgaa tcagctgaat cgccttaaca tcagatgaca ataccgtatc taaaacagag
     5041 gatgcatcgt taaattcagg atcttgtgtt aagtaagcga ttttgtaatc attggcttta
     5101 gaaaatggtg aatggtctcc gtcaaaacca atccttcccg acaagacatc taaaagagtt
     5161 gtttttcctg ttccattaac cccaataatc ccaatacggt caaagtcatg aataataaag
     5221 gaaatatcct gaaagactgt tttatctccc accgtttttg tcaatttctc caccaaaaaa
     5281 tggctcatgt tgctaattcc tctctaacaa atgcttcaat tgtagtgaaa tcattatcta
     5341 ggcgtccctc tacaatcgct aattcaactt tctcaagcat aagccctagc tgaggacctg
     5401 gtttcatccc aaaatcctta atcaggtgag aaccattaag gacgatatcg tatttgttat
     5461 gaatggctag cgcttgatct aaagcttcaa tgtggtccat gtcaacagat aagctttgag
     5521 cttttcggag gccttccact agacttgcca tttccttgcc gtactggtaa atatccaatt
     5581 tttcaaaaga tctttcctga cgaattctat aaagagcaat caactttgtg acataacgct
     5641 gaaaatcatt tgaagtcttc catgctttta ggaagctttt aggatcctca atggctaaac
     5701 taatcatcac ataagcccaa gcttggtggt gatcactaaa ggtaaagtta tctttcaaag
     5761 aaactatcag atgattcaag cctgcttcct gctgcttcaa gcctggtaaa tagtcataag
     5821 cctgacaagc aatcatggca gaaatccctt ttcgccagtg cggtgccatc aataatttat
     5881 caaattcagt aaaagaacgt tccacagaaa tcttttccaa tagaggtgaa tggctcctca
     5941 tagcttcaaa agttgcagct tcaatgtcaa aatccagact cgccgcaaat cgaaagcctc
     6001 tcataatgcg tagtgcatct tcttcaaaac gttcctctgc tttacccact gctcgtaacc
     6061 gtttttgctc caaatcaatg agtcctctaa atttatcaat aacttgacca ttttcatcca
     6121 aggccaaggc attgacggta aagtctcttc gttttaagtc ttcctctaaa gagcgcacaa
     6181 aagaaacctg actaggacgg cgatagtcaa catagacatc ttctgtccta aaggttgtga
     6241 tttcatactc accgccattt tcaagcacga gcactgtacc atgttcaatg ccaacatcga
     6301 cagttctgtt aaaaatcgct ttagtctctt caggatagga actagttgca atatctacat
     6361 catgaatggg acgctcgagt aaaacatctc tgacgcttcc tcccacaaag taggcttcat
     6421 aaccagcttc ttttatttta gtcaatatgg gtaaagcctt ctgaaactca gaaggcattg
     6481 tcattaattt catacgttgt tttctaacct atcatccaac tagcccaatc taaagtgtga
     6541 ttaggctact tgggttctat cacattttgt tattgtttta gtgattcttg caattaacta
     6601 ttttttctaa tcgacaatta aagcctcggt gttacgccaa atgcaatggc tccttctcct
     6661 aaatgagtag caatcaccgc tccaaaatga acctcttcaa tgtcatattg ataaccactg
     6721 tcttgtaaga gtcgtttcaa ataatcagct ttgtcttgtg cttttgagtg aataatagac
     6781 acattatact gaccgtctgc tatcaagtca tttaaaatct caaccaagcg tttcatggct
     6841 ttcttttctg ttctcacttt ttcataaaca acaatttttc cctcttcatc aaagcgtaaa
     6901 ataggtttaa tactcaaaag atttccaaga agagcagacc catttgacag gcgtccgcct
     6961 ttaaccagat gattaaggtc atcaaccata ataaaggctg tcgtcctatc aatctgttct
     7021 tgcagcttgt ttaaaatagc ttgaaatgtc attccttgac gtgaccaatc tagcacattt
     7081 tttaccatac tacctaaagg agcagatgtg atcttactgt ctggaaatgc catttcaatc
     7141 tcaggatgtt cttcagctaa aaattgaata ttttgccaaa agcctgagat tcctccagct
     7201 aagaacaagc caataacatg tgtataaccc ttagaagaca aaagtcctaa aagattatct
     7261 agttcagata aacttggctg acttgtcttg ggaagatttt gggagtcagc catcttttga
     7321 taaaaatcat ctatactcaa atttcgacct tcaaaatagg tctcatcgtc aatgataact
     7381 ggtatatcaa ggctaaaaat agctttatct tgtttcagat ctattggtag tgttgctgta
     7441 ctgtcagtaa ttactgctaa tttcattaat ttttaaactc caaatgaata cctggacgat
     7501 ccaaggcaat ttctgtgact tcataagtca atcgcttaac catgtctagc aaaggagcag
     7561 ctaaggattc aacttcctct tgcgtaaatt cgcttggttt atccactaaa cgatctaaaa
     7621 tgcgaaccat ttgtgagatg accccactaa taacaaattc ttctttgaca ataacaaatt
     7681 gcaatacaga tacaattact gtttcttttt gctgctcatc tttatcaatc aactgaaaag
     7741 tcacttcaaa attggtctct ggtgttccgt tttctttttc ccactctaaa tttctagcat
     7801 catagtggta ttgattgaca aattcttttt cacgaactaa ttgcattttt tattctcctt
     7861 ggtatcaata tgatccatta tagcatagat ttgaagatta ttaaagtagc ccctaaacta
     7921 ctattttcgc ataacgtttt aaacagtgct atctctcgaa cagatatcta ttttttcacc
     7981 tatttatatt tagtcgtcct tatactgaca ttatatcaaa aaacacccgt tagtggtctt
     8041 gtactgcacc tcaattaaaa cagaaccact ggtcaggtaa gttttaagtc aaggataaaa
     8101 aggtttatca ttaaggcctc atcatgctta gccaagtatt tcgaactagc ttgtcttagc
     8161 tctagtcgct caaacgtaaa tcctaggcgt tcaatccgcc gcaaaacctc tccaactaac
     8221 ccatacttaa acccatcggg cttaatcatc gctccgccct tcttctttta tccattataa
     8281 aataaaaacg ttttaacaga caaaaaatag gaaagtacca gactattgga tttatttttt
     8341 tatctcaaac tccattaacg atgttgagtt aaaggcattc aaaacaacat agatcgtaag
     8401 ctaacaagat tttttatcaa ttgaacctat cgtccccagt tataccacga cctcttctgg
     8461 atgaggtctt tttttatttg tctaatttca tcaacgcttc ttcccttctt tcttctatca
     8521 cagctctcct attgctcact tcctcatgca gcaacatatc atcaaaaaac cgttcatttt
     8581 taagcacaac cactactgta tctcttgtga tgtctccatt gcaatcgctt gtttaatttt
     8641 attaaaaatt atttaaaaaa ttaaatatta t
//
LOCUS       DAUGOH010000051         8491 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUGOH010000051 DAUGOH010000000
VERSION     DAUGOH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8491
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.051"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..2541)
                     /locus_tag="VH957_001521"
     CDS             complement(<1..2541)
                     /locus_tag="VH957_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ8559417.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMSIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLSLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLL"
     gene            complement(2624..4243)
                     /locus_tag="VH957_001522"
     CDS             complement(2624..4243)
                     /locus_tag="VH957_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8559418.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATDDSILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(4322..5194)
                     /locus_tag="VH957_001523"
     CDS             complement(4322..5194)
                     /locus_tag="VH957_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8559419.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMTSNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    5317..5558
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5613..6635
                     /gene="trpS"
                     /locus_tag="VH957_001524"
     CDS             5613..6635
                     /gene="trpS"
                     /locus_tag="VH957_001524"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEQ8559420.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     gene            6943..8424
                     /gene="guaB"
                     /locus_tag="VH957_001525"
     CDS             6943..8424
                     /gene="guaB"
                     /locus_tag="VH957_001525"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEQ8559421.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         2852 a         1376 c         1619 g         2644 t
ORIGIN      
        1 caaaagcata taagcgataa ttcctacgca agatagagat aaccctaatt taaaaccatt
       61 aggaataaag gtaaggataa cacgtccctt tcctttagga atagtaactg atagaaatcc
      121 tccttgtgct tttttgactg gaagattttt cccatctttt tgtgctgacc aacctttatc
      181 gtaaggaagt gtaaaaataa gagaaccttt cgtttttgaa ttataatcag tgattaccgt
      241 attactttta gcgtaagtat gaacattttt ttgtttaata ctattcattg cttcaaggta
      301 agattcaata gacaaactat aaaaatgagg ttccttaaaa ctaatttgtt tattttttgg
      361 aaaaacaaac gaaaatgtag caactttggc atcggcgaaa tatcctaaat caaaaaaaga
      421 gtaagcgtta tctgtagtat atatgaaatt atgattatct gtctgaatac gcacctcttt
      481 agcatcagga tttgaaaata taatattggg tatgctaaca tagagttgac tatgtttagg
      541 gatgttaatt tgataattaa gggtaacgga gttttgataa tcagaagctt gtgcagatat
      601 ttgtccgtta aattgattag caccagaaat aagttgagct ggttgtaagt taaaataggt
      661 taaagatttc ccacttagtt ggttaagtaa tttggtttgg ttatcaaggg tattgacatt
      721 taggttgaca tctttgtaaa cattacgtgt taatatagct aaagggctac tatagtgatt
      781 ttgataaaga gtagtattcc cgctagtttt tagttttgta aatccaaatt tatttagagg
      841 tccttcgcta agattatatt ttataccaag tagactgtcc ataataatag tattgttttg
      901 gtatctaagg tttaaatttg tgcctttaga ctgaaatccc aatcgatcca ataaagaact
      961 agatagtcta tttcttacag aggaaaattg tgaaatgccg taataattaa atttcatgct
     1021 atcgttccct gtttggggaa gtagcctttc cattctaaaa aaaggttgac tattttttga
     1081 cacagagttg acaaggttgt taatatcctt taattgacta ttatatatct gtcgtgatgg
     1141 gaatccccac tccttattaa ttccttgaag ctggtagtag gtgtttaacc ctgattcaag
     1201 aaggctaaag ataagtatga aagcagaaat aaaagtagat gggatttgag aatttctaaa
     1261 cgaaaatagt gaaatagtat aacctaataa taaaaaaaca ctaagtaaaa aaagagttaa
     1321 aggtagaaaa ttatattgtt gagaaaagct ataaggaaga gatgtcagta taatgaggaa
     1381 aataaaagca aaacctgctt ttatttgagt cacttctttt agtcgagaga gagtctcaca
     1441 tgcgagtaat aggataacta ttgaaaaaga ccaagcgtag cgatgcaaaa acatatttgg
     1501 tgagtgcatc ccctgccaaa aaagatcaag tggctgtagg taaaaactta ttataataaa
     1561 agttaacaag caggcattgg ctaattttat ttttaaaggg atactttcta aagtaaaata
     1621 aataacacta agcattaggg gaaataatcc tacgtaaatc ataggcagag cattaaactt
     1681 ggtagtatcg tacactccta ttgagagctt agcaggtata tccaaaaacc aagcattgtt
     1741 cgtaactaac tgttttaccg gggatagatt ctctccataa gttgacaaat ctagataggt
     1801 aggaagtatt actagagcac ttgttaaagc agcacatatt gacacagctg taaacctaac
     1861 aaaagcgata aacattttgt taaaatcatt cagacttaaa agacaaacta aggcgtaaag
     1921 aatacaaaaa agagcaatca tgtagccaaa gtagtaattt tgaatgaata ataatgatat
     1981 cgaaagataa taagttctag ttttattttc tgtgataagt ttatttaatc caagtacaac
     2041 aagtggaaga agaatgaaaa catctaacca agaatttagt tccatttgac ttgtcaagaa
     2101 gctcattaag ctataaaaaa ctgagatgga aatcatcaag aaagcactga tttttggata
     2161 taatctatga aaagaatagc atgcagctaa tcctattaac ccaaatttta tcaaggtaaa
     2221 caaatagata gcatctggca tagaggttaa attaaaaaag aaaagtaatg gagaaaagaa
     2281 actgccaaga taataacaca ttaaagcata aaaatttatc cctagtccgc ttgtaaaggt
     2341 ataaaaaaaa ctatcagaac cgtgcatgat gttacgaaag ttctgcgcaa aaataacata
     2401 ctgatgaaaa gcatcactag ctagaattgt tttatcacta ttataataaa tgctcatcga
     2461 tagaaggatg ataaatataa tactaagagg gaacaaaaaa ctagcaagtc cagcaattat
     2521 ccatttatta ttatttttca taaattatat ggtctttcgt ttacaaattt taaaaaagag
     2581 gctaggaaga gatcttctta gccacctcat ttatcataag gttttatttc caaagttcag
     2641 caactcgggc ttggacttct ggattgtcaa ggaattcgtc ataagtttca tctatacggt
     2701 cgataacacc attttttgaa ataacaacga tgtggttagc aatcgtttga ataaattcat
     2761 ggtcatgact ggcaaagata acagattctt tgaagtcttt gataccatca ttaaggcttg
     2821 aaatagattc caaatctaag tgattagttg ggtcatcaag aataagaacg tttgatttca
     2881 atagcatcaa tttagaaagc atgacacgca ctttttcgcc accggaaaga acgttaacag
     2941 attttttaac ttcgtctcca gagaaaagca tacgtcctag gaaaccacgt aaaaaggtat
     3001 catcatcttc accttttgag gcgaattgtc gtaaccattc aaggatggaa tcatctgttg
     3061 caaaatcttt tgaattgtct tttggcaagt aagaacgact tgttgtcact ccccatttaa
     3121 tggttccttc gtagtcaata tcatctgcta aagcacgcat aagagcggtt gtttgaatat
     3181 cattttgacc aataatagca gctttgtcac ctggacgtaa aatgaaactg atattatcaa
     3241 tgattttctc tccatcgatc gttacagaaa gattttcaac agtgaggaag tcatttccca
     3301 tttcacgctc tgctttaaaa ttaataaatg ggtatttacg gcttgaggga acaatttctt
     3361 ctaattcaat cttatcaagc atttttttac gagaggttgc ttgttttgat ttagatgcgt
     3421 ttgctgagaa acgggcaacg aattcttgta attctttgat tttttcttcg gctttagcat
     3481 tgcggtcagc ttgtaaacga gcggctagct cagaagattg tttccagaaa tcgtagttac
     3541 ccacaaagag tttgatttta ccaaagtcaa ggtcggccat gtgagtacat actttattca
     3601 agaagtgacg gtcatgggaa acaacgatga ctgtattttc aaaatcaatc aagaaatctt
     3661 ccaaccatga aatagattga atatcaagac cattggttgg ctcgtcaagt aataaaacgt
     3721 caggcttacc aaagagcgct ttagcaagaa ggactttcac tttatctcca ttagccagtt
     3781 cactcatatt ttggtagtga aggtcttctg gaatatttag attttggaga agttgagaag
     3841 cttcactttc tgcctcccag ccacctaatt cagcaaagat accttctagc tcagcggcac
     3901 gaaccccatc ttcttctgaa aaatctgctt tcatatagat agcgtctttt tctttcatga
     3961 tattgtaaag ttgctcatta cccatgatta caacatcaat cgcacgttct tcttcataat
     4021 caaaatgatt ttggcgaaga acagataagc gttcgtcagg tcctaaagag atatgaccag
     4081 tacttggttc aatatctcct gcaaggattt taagaaaagt tgattttccg gcaccattcg
     4141 caccgattaa gccgtaagta ttgccggctg tgaatttgat attaacatca tcaaatagtt
     4201 ttcgatcact aaagcgtagt gatacatcag aaactgtaag caatttgtca cctcatttta
     4261 tttatctaag cttcattgta cctaaaatag tccccttttt caatcagaaa agggctaatc
     4321 actacatagg caataaaacg tctttgtctt cacgtttgta ttgtttagtc aaactaaatc
     4381 ctcttcccat aacttgagct gctggcatga caacaataaa ggctgtgtcg tcaatttcga
     4441 ggattttttc ttggagagta ggtaattcgt gacttgatac aatagccatt aacataattt
     4501 tatcagaagt agtataacca ccgcgaatag gaagtttagt cactccacga tccataacag
     4561 ttgtgatata ttctcgaata gcttgataat ctttggaaat aatcataaca tttttggatg
     4621 agtcaaagcc attttccata acgctaatca cataaccaat tacgaaaagt ccaatcgtag
     4681 aatacatcac gtcatctgca gaaagtgcaa taaatcccat aaggacacta ataccatcta
     4741 caattgtcat tgcaactcca agagataaag gagagtattt atgaagtatt tgtgttagaa
     4801 ttccagttcc tcctgtcgaa gagtttcccc aaaaaaccat tcctaaacca atgccacaga
     4861 taataccacc aaaaatagct gctaacaact gattgtgtgt cagagtaggt aatgaattgg
     4921 ttgaacggat ggcaatagga tatatccaag aaccataaag tgttttaata aaattttgtt
     4981 ttccaagaaa gaagtaacac attaataata aggggatatt actagtcatt aaaaaaagcg
     5041 acggactaat gccaaataga gcttttataa caactgcaat accaaccata ccccctgatg
     5101 caatatgatt gtcgacaaac attgtattga aaccaatagc tgttatgaat gagccaattg
     5161 tgacaagtag taaatcaatc cctcgttttt tcatgctttt aatctccttt ataactggtt
     5221 aaaaatagta gactcattat ctcttaaatg tactgagacc gtcaagtcat attttcaaaa
     5281 aatctggtga acttgacaag aagtttaaaa tttcatagaa taaatctaaa ttagaagagt
     5341 attcttttca tgtttttaga gagttagtgg ttggtgcaag ctaacaacag aaaaggtgaa
     5401 atggactaat gattatttga aaggaaacca taactttcag gttggcaccc cttaccgtgc
     5461 agcttctttc attgagaaga ttgagatagt atctcgtttt gataaagcag atgctaattg
     5521 aggtggtacc gcgtattact tgtaataacg ccctcacgtt ttaatagcgt ggggactttt
     5581 tgctatatca agagatagtt agggagaaaa tgatgacaaa acctattatt ttaactggag
     5641 atagaccaac tggaaaatta catttaggtc attatgtcgg aagtcttaaa aatcgtgtct
     5701 ttttacaaaa tgaaaacaag tataagatgt ttgttttctt ggccgatcaa caggcactga
     5761 cggatcatgc taaagaatcc gaattaattc aagaatctat tggaaatgtt gccttggatt
     5821 acctctctgt cggtttggat ccgaagcaat caacgatttt tattcaaagt cagattccag
     5881 agctagctga attgagcatg tattatatga atctggtatc attagcacgt ttggaaagaa
     5941 atcccactgt taaaaccgaa attgctcaga aaggttttgg cgaaagtatc ccatctggtt
     6001 ttttggttta tccagtatca caggccgctg atattacagc atttaaagcg aatttagtac
     6061 ctgtaggtaa cgaccagaaa ccgatgattg aacaaacacg tgaaattgtg agaagtttta
     6121 atcatactta ccatacagac tgtttagtag aacctgaagg tatttatcca gaaaatgaaa
     6181 aagctggacg cttacctggt cttgatggca atgccaaaat gtctaaatca ttgggaaatg
     6241 gaatctatct ctcagatgat gcagataccg ttcgcaaaaa agtgatgagc atgtatactg
     6301 atccaaatca tattaaaata gaagatcctg gtcaaattga agggaatatg gtctttcatt
     6361 atttggatat ttttgctaga aaagaagatc aagctgatat cgaagcaatg aaagagcatt
     6421 atcaaagagg tggtttagga gatgtgaaaa cgaaacgcta ccttctagat attttagaac
     6481 gtgaattagc acctattcgt gaaagacgtt tggagtacgc taaagatatg ggagaggtgt
     6541 tccgtatgtt acaagaaggt agtcaaaaag caagaactgt ggcagccaag actttatcag
     6601 aagtgaagtc agcaatgggt attaattatt tttaatgttt tagagaaaaa gctaagttag
     6661 taatgataag ataattacta ttatcaaagc aggacctaat ttgtcatttc tttacaggat
     6721 agtagagatt atgttttata tagtcttatt tttgattaaa aataagaccc aaatgaattt
     6781 tttgattaat aaaaaacgga taatactgat atattatgct gatagtgact tcagctgtag
     6841 gaatatttta ttgacaaatg attttagcgt gatatgatag taacaataaa aaatagacca
     6901 gggtaatatt ccctaaaaat aaaagaaaag aggattatct ggatgtcaaa ttgggacact
     6961 aaatttttga aaaaaggcta cacttttgac gatgtcttgc ttattccggc agagagtcat
     7021 gttcttccaa atgaagttga tttaaagaca aaactcgcag acaatttgac attaaatatt
     7081 cctattatta cagcagctat ggatacggtt actggtagta aaatggctat tgcaattgcg
     7141 cgtgcgggtg gtttaggtgt tattcataaa aacatgtcta ttactgagca agcagaagaa
     7201 gttcgcaagg taaaacgttc tgaaaatggt gtcatcattg atccattctt cttaacacct
     7261 gaacacaagg tttcagaagc tgaagaatta atgcagcgct accgtatcag tggtgtgcca
     7321 attgttgaaa ctttagcaaa ccgtaagttg gtcggtatca ttactaatcg tgatatgcgt
     7381 tttatttctg attacaatgc accaatctct gaacatatga ctagtgagca cctcgttacg
     7441 gctgctgttg gtacagatct tgaaactgca gaacgtattc ttcatgaaca ccgtattgaa
     7501 aaacttcctt tggttgataa tagcggtcgt ctgtctggtt taatcactat caaagatatt
     7561 gaaaaagtaa tcgaattccc acatgctgct aaagatgaat ttggccgtct tctggtcgct
     7621 gctgcggtag gtgttacctc agatactttt gagcgtgccg aggccttgtt tgaagctggt
     7681 gcagatgcga ttgttattga cacagctcat ggtcattcgg ctggtgttct tagaaaaatt
     7741 gctgaaattc gtgctcattt cccaaatcgt actttgattg ctggaaatat tgccactgct
     7801 gaaggtgcgc gtgctcttta tgatgcaggt gttgatgttg ttaaagtggg tattggtccc
     7861 ggatctatct gtaccactcg tgtggttgca ggtgtcggtg ttcctcaagt gactgctatt
     7921 tacgatgctg ctgctgttgc tcgtgaatat ggcaaaacga ttattgctga tggtggtatc
     7981 aagtattctg gcgatattgt taaggctctt gcagccggcg gtaatgctgt tatgcttgga
     8041 tcaatgtttg caggtactga tgaagctcca ggtgaaactg aaatctacca aggccgtaag
     8101 ttcaaaactt atcgtggaat gggttccatt gcagctatga agaaaggatc aagcgatcgt
     8161 tacttccaag gttccgtaaa tgaagctaat aaactagttc cagaaggtat tgaaggccgt
     8221 gttgcttata aaggagctgc ttcagatatt gtcttccaaa tgttaggtgg tatccgctca
     8281 ggtatgggct atgttggcgc aggtgacatt caagaattac atgaaaatgc tcaatttgtt
     8341 gaaatgtcag gtgcaggctt gattgaaagt catccgcatg atgtccaaat cacaaatgaa
     8401 gcaccaaact attctgtgca ctgataattt aatttagtaa ctttaagggc tgacatattg
     8461 tgccagctct tttttatatt aaaaaatgat a
//
LOCUS       DAUGOH010000052         8487 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUGOH010000052 DAUGOH010000000
VERSION     DAUGOH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8487
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.052"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            67..2427
                     /locus_tag="VH957_001526"
     CDS             67..2427
                     /locus_tag="VH957_001526"
                     /inference="COORDINATES: protein motif:HMM:NF014273.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8559422.1"
                     /translation="MEFVDKKLSEITPYKNNPRNNDEAVGPVAESIKEFGFKVPIVVD
                     KNGEIVNGHTRYKAAQKLGLETVPVIVADDLSEEQIKAFRLADNKVGEIADAYEVKAT
                     RERNGNYSLYIKYPLDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIF
                     ARHISMRTQDIALKPFVNGASVGAESALEIWKKNLVGDDKFDVKSDILTLGSFNWEID
                     KIGNARGALGGVAGSILDVYGGEYEFDNRTIILRKQMGRKAPTVLEYGRNIVSVEEER
                     LLDGNYTSIYPYVRYTPQPKPQEEPPGKPHVGEHKQPEEQLVTLPEFILDGQYLSLYA
                     QRRIQMVDLSSHFNDDKNKKEPTIEEIRKLAQKYLKDNNVGAPKVSIEVDYIDLSQTL
                     DYQDFRVMEEVELCDIVPLYYPKFGITTESEKVVEIVYDVYTDSNHTIKLGTIGQSIS
                     KSLTGGVSERINALENNQKVITNSQKQFELNLPKYLNDLNGKRVWYEKPDDNIEHKIG
                     DYWFEKNGKYQRTWIWDGNQWVKVLDTEDLNPNQRAFDAAIAELEKAKKAQEEINQRT
                     DKELEEFRATLKNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTA
                     EILGNNGKTRYNKNLLVGEPNRTKSYDQDYIEVEANDGGFKRGETYTISFSQTCEPLK
                     KVAVTLTQANNKGVKLVLTPTKAKMEAQTFEVAKDKQSIEVYPLSYTAVLTGDWYKSK
                     QIDLNASEVRELALEMDYKEIADAKGATITGAWSDSPQIILDGGKK"
     gene            2424..3446
                     /gene="hylP"
                     /locus_tag="VH957_001527"
     CDS             2424..3446
                     /gene="hylP"
                     /locus_tag="VH957_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase HylP"
                     /protein_id="HEQ8559423.1"
                     /translation="MSENIPLRVQFKRMTASEWARSDVILLESEIGFETDTGFARAGD
                     GHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETAQKLQQKADKETVYTKAESKQELD
                     KKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSSRGAGVVVYSNNDTSDGPLM
                     SLRTGKETFNKSALFVDYSGKTNAVNIAMRQPSTPNFSSALNITSGNENGSAMQLRGS
                     ERALGTLKITHENPSLEANYDKDAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKL
                     LRIRNLNDDKFYVKPDGGFYAKETSQIDGNLKLKDPIANDHAATKAYVDGEVEKLKAL
                     LTAKQM"
     gene            3459..5345
                     /locus_tag="VH957_001528"
     CDS             3459..5345
                     /locus_tag="VH957_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8559424.1"
                     /translation="MSRDPTLTLDESNLVIGKDGRVHYTFTASQDNQTVRLASNCLGT
                     AHFNQLMIERGDKATGYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISDDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQTTASQISQEIRNREGAVSRVQQDL
                     ASYQRRLQDAEDNYSSLTHTIRGLQSEVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNSAKLDFNSNATINFNSRDNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGMRCFRHATGYNHTAAVDQTEIYGDSVLIADDFN
                     INRGFKFRPDKTKKILDMNNLYDAVVALGRCWGHLRNAGWDTARSNFIAAVTRELSNY
                     IDII"
     gene            5357..5785
                     /locus_tag="VH957_001529"
     CDS             5357..5785
                     /locus_tag="VH957_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ8559425.1"
                     /translation="MDLTLKNKDLNTFYSVLDKIKITNMRANRGRAKLLAKVVDKINE
                     YAKDEADIIDLYALKNKDGKFVIDEHKNIKIEDPKKIDELNDLLTELGNEDITIKGHE
                     YSKRFIDFLEYLAESEDEFTSEEIVLIDNILEQFEESKGE"
     gene            5788..6405
                     /locus_tag="VH957_001530"
     CDS             5788..6405
                     /locus_tag="VH957_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8559426.1"
                     /translation="MRNWKVTGKYPQYDSTGAVASTHIIITAEDGSVISQPIKQDLTS
                     TNDTEIIKAALEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEPFTYEAQTLEELESEDKVTVIKYAELVKQD"
     gene            6416..6715
                     /locus_tag="VH957_001531"
     CDS             6416..6715
                     /locus_tag="VH957_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559427.1"
                     /translation="MHFDLLQIGAACTALLSILGVWGFIVNPFKKAMEANEFAMAQLK
                     DSIKELAYELKNLDRDREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            6712..6897
                     /locus_tag="VH957_001532"
     CDS             6712..6897
                     /locus_tag="VH957_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559428.1"
                     /translation="MNKWFKKVAIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKEEE"
     gene            7010..8212
                     /locus_tag="VH957_001533"
     CDS             7010..8212
                     /locus_tag="VH957_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8559429.1"
                     /translation="MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADSSWTGKSFDTKTQEEYQAGVVTDIVDRFRAYDSWDESIADHGQFLVDNPRYE
                     AVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALKNNKEETMTTA
                     NEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFGVDLWGNAIDLLDSASAQG
                     WEVHRMPTEANPKAGATFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYV
                     GAPARFNTRDFTGVIGWFYPPYQGDTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEIN
                     IRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGGSGMRNYLGIGQTDKDGNR
                     ISLWGKLN"
     gene            complement(8280..>8487)
                     /gene="speC"
                     /locus_tag="VH957_001534"
     CDS             complement(8280..>8487)
                     /gene="speC"
                     /locus_tag="VH957_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021733756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeC"
                     /protein_id="HEQ8559430.1"
                     /translation="MDNYKIYDATSPYVSGRIEIGTKDGKHEQIDLFDSPNEGTRSDI
                     FAKYKDNRIINMKNFSHFDIYLEK"
BASE COUNT         2754 a         1629 c         1976 g         2128 t
ORIGIN      
        1 atctatggtt aaccaattag tcatcacatt gtggtgactt tttattatgt aaaaaaggaa
       61 taaaacatgg agtttgtgga caaaaaatta agtgaaataa caccttataa aaataaccct
      121 agaaacaatg atgaggctgt tggaccagtt gctgaatcta ttaaagagtt tggttttaaa
      181 gtgcctattg tcgttgataa aaacggcgaa atcgtaaacg gccacactcg ttataaagca
      241 gcccaaaaat tagggctaga aacagttcct gttattgtcg cagatgactt atctgaagag
      301 caaattaaag cgttcagact tgctgacaat aaagttggtg agattgcgga tgcttatgag
      361 gttaaagcca ctcgtgagcg caatggtaat tactcactgt acatcaaata tccgctagat
      421 ggtgtctttg cctcagtttt taaagaggaa atgaagatta agtctgacgc tggtcgtaga
      481 accaaatggc agacttttga gattaatcgg gtactacgaa atagtaaaga ccacatcgag
      541 atttttgcgc gtcatatctc tatgcgcaca caggatattg ctttaaaacc gtttgtaaac
      601 ggtgcgagcg taggagccga atcagcttta gaaatctgga agaaaaacct tgtcggtgat
      661 gataagtttg acgttaaaag cgacatctta acgcttggta gctttaactg ggaaattgat
      721 aaaatcggca atgcccgtgg tgctctagga ggtgtcgctg gctctatcct agatgtttac
      781 ggtggtgagt acgagtttga caaccgtaca atcatcttac gcaagcaaat ggggcgtaaa
      841 gctcccacgg tattggagta tggccgtaat atcgtcagcg tagaggagga gcgattgcta
      901 gatggcaatt acacctctat ctatccttac gtaagatata cgccacaacc aaaaccgcaa
      961 gaggaacccc ctggtaagcc gcatgtaggc gagcataaac aacccgaaga acagctagtg
     1021 acattgcctg aatttatcct agatggtcag tatctcagct tatatgctca gcgcagaatc
     1081 caaatggttg atttatcaag tcattttaac gatgacaaaa ataaaaaaga gccaacgatc
     1141 gaagaaatcc gaaagctggc tcagaaatac cttaaggata ataacgttgg tgcaccaaaa
     1201 gtcagcattg aggttgatta tattgacttg tcacaaacgc ttgactatca agattttaga
     1261 gtcatggaag aggttgagct ttgcgacatt gtaccacttt attatccaaa gtttggcatc
     1321 acaactgagt ctgaaaaagt cgttgagatt gtctatgacg tctatacaga tagcaaccat
     1381 acaataaaac ttggcacgat tggtcagtcc atctctaaga gtttgacagg tggggtctca
     1441 gagcgtatca atgctttgga aaataaccaa aaggttatca ccaacagcca gaagcagttt
     1501 gaactcaatc tgcctaaata cctcaatgac ctcaatggta aacgcgtttg gtacgaaaaa
     1561 ccagatgaca atattgagca caagataggc gactattggt ttgaaaaaaa tggcaagtat
     1621 cagcgtactt ggatttggga tggcaatcaa tgggtcaagg tactagatac agaggattta
     1681 aaccccaatc aacgagcttt tgatgccgca atagccgaac tcgaaaaagc aaaaaaagcg
     1741 caagaagaaa tcaaccagcg tactgacaaa gagcttgaag aatttagagc caccctcaaa
     1801 aacctagctt taccagaaga agcgattaaa aaaatcacag aggctatcaa agttgatgac
     1861 atcccgtcta ttaaacaaag ctttgatgac ctcaaaaata gagtgagtga gacaagcgaa
     1921 gaatctcgtt taactgccga aattttagga aacaacggta aaacccgcta caacaaaaat
     1981 ttattggttg gtgagcctaa tcgcacgaag tcttacgacc aggattacat cgaggtagaa
     2041 gccaacgacg gtggtttcaa gcgtggcgag acctatacga ttagctttag ccagacatgt
     2101 gagccactca aaaaagtggc tgtcacgctg acacaggcta acaacaaggg agttaagtta
     2161 gtgctgacac ctaccaaggc taagatggaa gcacagacgt ttgaggtcgc taaggataaa
     2221 cagtctatag aggtttatcc tttgagctac acggctgttt taactggcga ctggtataaa
     2281 tctaagcaga tagatttaaa cgcgtcggag gtgagggaat tggctctgga gatggattat
     2341 aaagagattg cagatgccaa aggtgcaact atcacagggg catggtcaga cagtccacaa
     2401 attatattag acggaggtaa aaaatgagtg aaaatatacc gctgcgagtc caatttaagc
     2461 ggatgactgc tagcgagtgg gctcgtagtg atgtcatctt actggagagt gagataggct
     2521 ttgagacaga cacaggtttt gccagagcag gtgatggcca caatcgattt agtgaccttg
     2581 gatacattag cccactcgat tacaatctac tgactaacaa gccaaatatc gatggattag
     2641 cgacaaaagt cgagaccgct cagaaactac aacaaaaagc agataaagag accgtctata
     2701 caaaagctga atcgaagcaa gagcttgaca agaaattaaa tctcaaaggt ggcgttatga
     2761 caggtcaact aaaatttaag ccagccgcca ctgttgctta ttcctcgtca acgggtgggg
     2821 cggtcaatat tgacttgtcg tctagcagag gtgctggtgt tgttgtctat tctaacaatg
     2881 ataccagtga tgggccgcta atgagcttgc ggacgggtaa agagaccttc aataaatcgg
     2941 cgctttttgt cgattacagc ggtaagacta atgccgttaa tattgcgatg cgccagccaa
     3001 gcacacctaa tttttcctct gcgcttaata ttactagcgg caatgaaaat ggtagtgcga
     3061 tgcagctacg agggtcagaa agagcgctag gaacgctaaa aattactcat gagaacccaa
     3121 gtcttgaagc gaattatgat aaagatgcgg cagcgttatc tattgatatc gttaaaaaac
     3181 agaaaggcgg aaaaggtact gctgctcaag gaatctacat taactcaaca tcaggcacga
     3241 cagggaagtt gcttaggatt agaaacctta atgatgataa gttctacgtc aagcctgacg
     3301 gtggttttta tgccaaggaa acttcgcaga ttgatggcaa cctgaaactc aaggatccca
     3361 tagcgaatga tcatgcggca accaaagctt atgttgatgg tgaagtcgaa aaattaaaag
     3421 cactcttaac ggctaagcaa atgtaaaaag gaggagatat gagtagagat ccaacgttga
     3481 cattagacga gtcaaatctc gttattggta aggatggacg tgtgcattat acatttactg
     3541 ctagtcaaga caaccaaaca gttagactag ccagcaactg cttaggcaca gcgcacttta
     3601 atcagctcat gattgagcga ggggataaag cgactggcta tgtggcgcct gtggttgtcg
     3661 aggggacagg taatccgact ggactattta aagacctcaa agagattagc ttagagctga
     3721 cagatactgc taattcccag ctttggtcaa aaatcaagct gactaaccgt ggtatgttgc
     3781 aggaatacta cgacggtaag atcaagaccg agatagtcaa ctccgccaga ggtgtcgcta
     3841 cacgtatcag cgatgatact gataaaaagc tagcgctcat caatgacacc attgatggta
     3901 tcaggcgtga gtatcgagat gctgatagga agctatccgc aagctatcag gcaggcatcg
     3961 aggggctaaa agccacaatg gccaatgata aaatcggttt acaagctgag attaaagcct
     4021 cagcacaagg gctatcgcaa aagtatgatg atgagttgcg caagctatcg gctaagatca
     4081 caacaacctc aagcggcact acagaggcct acgagagtaa gcttgcgggc ttacgtgctg
     4141 agtttactcg ctcaaatcaa ggcacgagga cagagctcga gtcacaaatt agcggactaa
     4201 gagcggtaca acagacaacc gctagccaaa tctcacaaga gatacgtaac cgcgaaggtg
     4261 ctgtcagccg tgtgcaacag gacttagcta gctatcagcg gcgattgcag gacgcagagg
     4321 ataattacag tagcttaacc catacaatta gaggtttgca gagtgaagtg ggatccccga
     4381 ctggtaaaat ccaatcacgc cttactcaac tagcaggaca aattgagcag cgggttacta
     4441 gagatggtgt catgagtatt attagtggcg ctggagacag cattaaatta gctatccaaa
     4501 aggctggcgg cattaatgcc aaaatgtctg gtaatgagat tatctcagca attaacctca
     4561 actcctacgg agtaacaatc gcaggtaaac acatcgctct cgatggcaat acgacggtta
     4621 atggcacctt taccacaaaa atagccgagg ctatcaagat tagggctgat cagattattg
     4681 caggcacgat tgacgctgct aggattagag tgattaacct taacgcaagt agtatcgttg
     4741 gtttagacgc taactttatc aaagctaaaa ttggctatgc tatcactgat ttgctcgagg
     4801 gcaaagtcat caaagctcgt aatggcgcta tgcttatcga ccttaacagc gctaagcttg
     4861 attttaacag taacgcgacc atcaacttta acagccgaga taacgctcta gtgcgtaaag
     4921 acggtacaca cactgccttt gtacacttta gtaatgccac accaaaaggt tatacaggtt
     4981 cggcactata tgcctctatt ggtatcacct catctggtga tggggtcaac agtgcgtcat
     5041 ctggacgttt tgcgggtatg cgttgcttta ggcacgctac aggctacaac cacactgcgg
     5101 cagtcgacca gacagaaatt tatggtgata gtgtacttat tgcagatgac tttaacatca
     5161 atagaggctt taagtttaga ccagacaaga cgaaaaaaat ccttgatatg aacaacttgt
     5221 atgatgctgt tgttgcactc ggacgttgct ggggacatct gaggaatgcc gggtgggata
     5281 ccgctcgcag caattttata gctgctgtca ctagagagtt gagtaattac attgatatta
     5341 tttaaaagga gacaacatgg atttaacact aaaaaataaa gacttaaaca cgttttatag
     5401 cgtacttgac aaaatcaaaa tcactaatat gcgtgccaac cgtggacgtg ccaagctact
     5461 ggcaaaagtg gtcgataaaa tcaacgagta cgccaaggat gaggctgaca ttattgactt
     5521 gtacgctcta aaaaataaag acggcaagtt tgtcatcgac gagcataaaa atatcaagat
     5581 tgaggaccca aaaaaaatcg acgagctcaa cgacttactg acagagcttg gtaatgagga
     5641 catcactatc aaaggccatg agtattcaaa acgctttatc gatttcttgg aatatctagc
     5701 cgaatcagaa gatgaattta catcagagga aatcgtctta attgataata ttttggaaca
     5761 atttgaagaa agtaaaggag aataattatg cgcaattgga aagtaacagg gaaatatcca
     5821 caatatgaca gcacaggagc agtcgcaagc acacatatta ttatcactgc tgaggatggc
     5881 tcagtcatct ctcaaccaat caagcaggac ttaacctcaa ctaatgacac agagattatc
     5941 aaagccgctt tggaagaatt taaaaaatct gaatacgttg aaattgctat gggcgaagca
     6001 gtccaaaaag ttgatgactt ggaaaaaatc tcacaagaaa ccgctaagac tgctaaaaca
     6061 gcccaaacag ccgctggact agctaaggtg tccgcagagc gtacacagcg gatgattaac
     6121 ttgcaaacca tccacgtatt gacaagtggt gggaaagttg aacctgatat ctacaaaggt
     6181 atgttagagc taatcgagcc agccaaaaaa ggtgagtatc aagcttatga cgtgtttacg
     6241 gtggttgaca gtactaaaga ggaagatggt gaagcaggcg aagggaactt agtctttgta
     6301 catgttaacg agccatttac ttatgaggca cagaccttag aggagcttga gtcagaggac
     6361 aaagtaacag tcatcaaata tgcggaatta gttaaacaag attaggggtg gttagatgca
     6421 ctttgattta ttgcagatag gagctgcgtg taccgctctc ttgtctatct tgggtgtttg
     6481 gggatttatc gtcaacccct ttaaaaaagc catggaagct aatgagtttg ccatggctca
     6541 gctcaaggac tcaattaagg agttagctta tgagcttaaa aaccttgatc gtgaccgtga
     6601 gattaccaaa aaaattatcg atcgccacga agagcgttta gggcgtgtcg aagacgaagt
     6661 tattatcaac aaagaacgta ttattacgct atttaaaaaa ggagaagaaa aatgaataaa
     6721 tggtttaaaa aagtagcaat caaaacaatc aaaacaatgg cacaaacagc tgttggtctt
     6781 atcgggtcaa gcgtgttgat tacggatatt aactggccaa cgatgttgtc agcggtatta
     6841 ctatcaggac taacttgtgt cctgatgaat gtgtcacaaa ttaaagaaga ggagtaacca
     6901 tgagaaaagc aatcacacaa ctagccgtca tcatagctat catagtgcta tattttccac
     6961 tggccgtgat tgctttgatt ttggctccat ttataggaga ggatgataga tggcattttt
     7021 agacaaaata aaaagcgcag ttatcgcaga gtggcacact cataagattt tgccatctct
     7081 gacagctgct caagccattt tagagagcgg gtggggcaaa catgccccac acaacgctct
     7141 gtttggtatt aaggcagata gctcttggac tggtaaatca tttgatacca aaacccaaga
     7201 ggaatatcaa gcaggtgttg tcacggatat tgtggaccga tttagggcgt atgatagttg
     7261 ggatgagtcg atagctgatc acggacaatt tttagttgat aatccacgct atgaggcagt
     7321 tattggggag actgactata aaaaggcttg ttacgctatt aaagcagctg gatacgctac
     7381 ggcaagtagc tatgtcgaac ttttaatcca actgattgag gaaaacgact tacaaagttg
     7441 ggatagagaa gctcttaaaa ataataagga ggaaacgatg acaaccgcaa acgaaattgt
     7501 acaatactgt gttaaccttg ctaattcagg catgggtgtt gacaaagacg gtgctcacgg
     7561 gacgcaatgc tgtgacttgc cttgttttgt cgctaaaaat tggtttggtg ttgatctttg
     7621 gggcaatgcg attgatttat tagacagcgc aagtgcgcaa ggctgggaag tccatcgtat
     7681 gccaacagag gcaaacccaa aagcaggcgc tacatttgtc caatcagtgc cgtatcatca
     7741 atttggacat acgggaattg ttatcgagga tagtgacggt tacaccatgc gcactgtcga
     7801 gcaaaacatt gatggcaatc ctgatgcttt gtatgtcggt gcaccagctc gttttaacac
     7861 tcgtgacttt actggcgtga taggttggtt ttacccacca tatcaagggg atacagtcac
     7921 gcaaccagtc agcaccgagc cgcaaacttc tgacactatc gtagagacag caaaaacagg
     7981 cacctttacc cttgatgttg cagagatcaa tatcagacgc tggccaagtc tagccagcga
     8041 ggttgtaggt atctacaagc aaggtgatac tgtcagcttt gatagcgagg gctacgctaa
     8101 tggctattat tggattagct atgttggagg ctcaggtatg cgtaactacc taggtattgg
     8161 acagactgat aaagatggga atcgcatcag cctttggggt aaattaaatt aggaggtaaa
     8221 gctccgagat aagacaaaac cgctcagatt attctgggcg gttttttgtg tatgatgaat
     8281 tatttttcaa gataaatatc gaaatgacta aagttcttca tattgataat tctattatct
     8341 ttatattttg caaaaatatc tgatctagtc ccttcatttg gtgagtcaaa taagtctatt
     8401 tgctcatgtt tcccatcttt tgtgccaatt tcgattctgc cgcttacata aggagaagta
     8461 gcgtcataaa ttttataatt atccata
//
LOCUS       DAUGOH010000053         8412 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUGOH010000053 DAUGOH010000000
VERSION     DAUGOH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8412
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.053"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..620)
                     /gene="speG"
                     /locus_tag="VH957_001535"
     CDS             complement(<1..620)
                     /gene="speG"
                     /locus_tag="VH957_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEQ8559431.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     PPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEAVRIKKKQFTLQEFDFKI
                     RKFLMEKYNIYDSESRYTSGSLFLATKDSKHYEVDLFSKDDKLLSR"
     gene            complement(722..820)
                     /gene="ffs"
                     /locus_tag="VH957_001536"
     ncRNA           complement(722..820)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VH957_001536"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            1020..2252
                     /locus_tag="VH957_001537"
     CDS             1020..2252
                     /locus_tag="VH957_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEQ8559432.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANMPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDHLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(2866..3381)
                     /locus_tag="VH957_001538"
     CDS             complement(2866..3381)
                     /locus_tag="VH957_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEQ8559433.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(3381..4160)
                     /locus_tag="VH957_001539"
     CDS             complement(3381..4160)
                     /locus_tag="VH957_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8559434.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PEGINSKNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(4300..4839)
                     /locus_tag="VH957_001540"
     CDS             complement(4300..4839)
                     /locus_tag="VH957_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEQ8559435.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(4843..5154)
                     /locus_tag="VH957_001541"
     CDS             complement(4843..5154)
                     /locus_tag="VH957_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559436.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(5372..6514)
                     /gene="tgt"
                     /locus_tag="VH957_001542"
     CDS             complement(5372..6514)
                     /gene="tgt"
                     /locus_tag="VH957_001542"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEQ8559437.1"
                     /translation="MTDYPIKYRLIKTEKHTGARSGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            6733..7596
                     /locus_tag="VH957_001543"
     CDS             6733..7596
                     /locus_tag="VH957_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEQ8559438.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGSSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            7793..8412
                     /locus_tag="VH957_001544"
                     /pseudo
     CDS             7793..8412
                     /locus_tag="VH957_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2671 a         1697 c         1509 g         2535 t
ORIGIN      
        1 tctcgactta aaagcttatc atccttacta aataaatcaa cttcataatg tttactatct
       61 ttagtagcaa ggaaaaggct ccccgatgta taacgcgatt ccgaatcata gatattgtat
      121 ttttccatta gaaattttct tattttaaaa tcaaattcct gtaaagtaaa ctgtttcttt
      181 tttatgcgaa cagcctcaga gggcaaataa gtttctttcc catcttgatt taaaattcct
      241 acaaactgta atgatttatt tccttgattc gaatgtttta caataccacc ataaatatta
      301 tctacataag gtggggaaaa attataaggg agaccaaaaa catcgacctt atcccctttt
      361 ataaactgat cagtaatgcc taaagataca atagaatcaa cataaagaat acattccgat
      421 cttttttgtt tagtattaat atgtatgcta tttgtagtaa caaatgcaat ttctacattt
      481 tcataatcgc atggggtaat attataggca aaccttaaac ttctttttaa atcttttaaa
      541 ttttcatctg cataagctaa ttgacttcca tagctaaaaa cacatgataa tatgataatt
      601 gtcaaaatgt ttgttttcat ttaaaacttt ttatgtcctg ttttatacct cttaacctaa
      661 ataaaaatat caatcggttt caacaactga tgacactata gaaggaagag attactttag
      721 taaagtcaac aaaaaaagag cacacacccg aaaatcgctt agggctgctg gattcctccc
      781 ctgacccact tcacgcacaa gtgttgctcc gcctattatt atatcatatt acggacagtt
      841 tgcaagtttt ccaaataagt aaaatcactt tcaagtgagc atagcttcat tttgggacaa
      901 gatggactga atacctagaa aaatcatgac cctttccaaa cacgattttg ctttttgaaa
      961 atctttccct ctccccattc cagctattct ctatgttata ataagattat tagattagaa
     1021 tgggagttat gatgaaacaa aagattaaaa tcttaacagt aattggcctt atgacagttg
     1081 gtatgtctgc gtgtcacaac actagcaaac cttctaatac cgattctgtt ttttctttaa
     1141 ccggaaaaaa gcgccaacaa atcgtcaaac aagtaagaca acggtattat ttccaacaat
     1201 tatccaaaac cgaacaagaa aattacctca ctttatacga tagtctagca caatttcgtg
     1261 aaatcatcag tttgacgccg gcttctaaaa aaagcttaat taaaacgatt gacgcctttg
     1321 tgatggataa tcccgaattt tactggatta catctgccga ttatcgattt gagttttctg
     1381 atcaaacggt ctttgtcacc tttcctatcc cagaagatgc caagaacgtt tatcaagact
     1441 tgcaagcaat cggtaatgat atcgtcgcaa acatgccatc aaaggatcgc tatgagcagg
     1501 tcaaatattt ttatgaggtc atcattcgag acacagacta caataaaaaa gcctttgaag
     1561 cctatcaatc aggcagtcaa gcccaggtcg cttctaatca agacattaaa agtgttttta
     1621 ttgatcattt atctgtttgt aatggctatg cccaagcctt tcagtttctt tgtcaaaaag
     1681 ctggcattcc agtcgcctat atccgtggaa ctggtacatc tcagcaacct cagcaatctt
     1741 ttgcacatgc atggaatgct gttcaaatta ataacactta ttatggcgtt gatgtcactt
     1801 ggggtgaccc tgtttttgat aaccatctct cacatcaaaa gcaaggaact atcaattaca
     1861 gttttctatg cctgccagac catctaatgg ccttatcaca tcagccaagc aaagacattg
     1921 cttttaatac taaagaacgt tttgaaaatg tttggactat accttcttgt acagatgatt
     1981 ctttgcttta ttctaaacgt catcaaagct atatctcaac gtttgacagt gacgccatcc
     2041 ttgcaagcct tgaaaatcag ttgttaaata gacaagagcc actgtctcta caatttgctc
     2101 atcaagatga ttatcaacaa atggtaactg atttaacgac gaatcaaaca ggttatcata
     2161 accttttcaa tcagtattgg aataattata cgggctttac ctatggactc ttaccagaga
     2221 ctcttagtat ttcatttgct agtaggaact aggtttagac acatgaaaca caaagttaag
     2281 atgattatct ttgtcaaaca ttacaagaaa ttgatatact aacacaattg aaggcgatta
     2341 ttattctaac cgtcttcaat agatataacc ttttcagatt gagcacatct aatgcttgta
     2401 acattagcaa cagtgatgag ctctttttta atgctttagc aaaatatatc agctaagaca
     2461 aaagattaaa taactcaagc catgcctata agtcacttgt ttttaatccc tgtgtcagtg
     2521 tcaatctacg ccacagataa ctgacagctc tgagccctag aagtctaagc ttgataagtt
     2581 tactaaaaac aaaaataagg tgagccatta ctatctgttt ttagatagta aatcttttta
     2641 agaatgacta actcatctag tcatcacgtg ttttattttt cgattgtttt catctcgatt
     2701 gggtctgaaa aagagcgctt ctagtacttg gaaacgccct tttgtatatt ctatcttcgt
     2761 atgttgaatc taacaaccat tggaagaatg gtctgacgtt tcactcagta ttttgacagg
     2821 ctacccttca ccaaaaatgc atgtgataac aaactcctta aaactctagt caaagggatc
     2881 tgactgttcc ttgatcaaat gcttagctat ttttttgcgc tctcgccctt ggcggaaaaa
     2941 ggtttgcatg atgttagcac agtctgctgc tagcaggcct cgttcaactt gcacgcgatg
     3001 gtttaagcgc tcatctgtca aaatctggta aaggctgtct gctccaccaa atttttgatt
     3061 gctggctcca taaataacat gcggaatcct tgctagccca atagcaccac tacacatcac
     3121 acaaggctcg atggtcacaa agagtgtggt gtctaataaa cgccagttgc cttcatgagc
     3181 gttagcctcg ttaatagcca tcatttcagc gtgcataatg gcttggttac tctcttcacg
     3241 cgcattgtgc ccacgaccaa taatctcacc atccttgaca atgacacagc caatggggat
     3301 ttcagctttc tgtaaggatt tttcggcttc ttttaaagcc tcttgcatga aataagtttg
     3361 ctcttctaaa ctatatggca tcaagaaaga ctccccaagt tccaagattt gtgtggtaag
     3421 gcaaggtcaa caggaatatt acctgcatag gcctgtgttt cttgcctcaa cacttctaaa
     3481 tggtttttgg aattaatacc ttctggagga accggtggca tgtgggtcaa gacaagcttc
     3541 ttaacacctg cctggctagc cattagtcct gcttccttac tggtcaaatg ggccatatga
     3601 ttttcattgc cttcgtataa gtaaacatcc gctaagaaaa ggtctgcttc ttttgcgaag
     3661 tctgccaatc cttcaaaata accactgtct ccagtaaaga caagtacctg accagtcgct
     3721 ctttctacaa ttcgaaaggc ataacacaca actggatgaa ctgttttaag aaaggtaatg
     3781 tcaaaaggac caatctgttc aactccagta acatcatagg ctctaccttc tgaaacatca
     3841 ggaatgctta acttagcaaa ttcgtgtcgg tcctcatcat gcccataaat gggcaatact
     3901 ttaggctgcc acaggtgttt aggataaagt tgaaaataat ggcgcaacac gcctaaatcg
     3961 gccacgtggt ctggatggta atggctaata atcactgcat ccaaatcgag aggactgatt
     4021 tctttttcca gctcattgag cgctcgacta ccagcatcca tcaataactg aaagccgtca
     4081 tgtcctgtga ccaaataaga ggttgtgcct gcatcttgat agggataggc tccccaagac
     4141 cctaaggtgg ttaatttcat ctcaaaccct tctttcttgc tttaactctt attataacaa
     4201 aaattagtgt caaagaggat tgagacccac caaaaacagg tcctagcaga taaatctgcc
     4261 aagacctgtt caacacaact taactatttg atgattagat tactgttttg tattcaaaaa
     4321 actatctttg tatttaacag cgataatggt cgcaatgatt gctttgatgg tatctcctgg
     4381 aataaagacc aagtttgaca aaagcgatgt cacaagagac atgccagtgt aggctgccaa
     4441 ccagatagca cccagaacat caaccagtac aactcctgag attaaaagag ctaggaatgc
     4501 taatggcgtg ctttttgaga accagttgcg gtaaagtaat gaaaagacaa taggcacaag
     4561 aaggtaggca ataacatagc cagcagatgg ccccatcaat actggaatgg ttgttcttga
     4621 gcctgagaaa acaggtaaga aaaggccaat cactaaaaat aagaaaacag ataaggttcc
     4681 ctttttacca cccagcatca atccagccaa catgacacct aagttttgta aaacaatagg
     4741 gactgggata aagcctagcg ggatagcagg aataaagcct aaaataataa tcaaagtggt
     4801 catcatagcc accttaacaa gttctttggt tgtaaacatc agttacgact cctttaaaaa
     4861 atagatatcc ttgtgcctat gacaggctgg attaaaggga ctttgacaat aaggacagca
     4921 tccacaacca tactcagcta ggctcaagag ctttcgacaa tgcccacaaa taacaggaga
     4981 tgtttcttga tgtcctgttg gcacaaaggc atgatctgtt aactggtcat ggcaatggta
     5041 acaagcataa taagtctgac aaaaagcaca tttgagccca acaatatcaa gcggggtatg
     5101 ataatgtagg caccgatact cttggtcaag gtcaattcca aaacagtccg tcatatctca
     5161 tcctcttgta atagtttaat caaaagctta tgatttgtca actctatttt tacaaaaggg
     5221 taactgtttt ctgaaaaaga acacgtaaaa caagaacttt cctttaaaaa gtgacctatc
     5281 agttgaaagc aataggacat ccgtctatac aaaaaaacct gaaaccaaag acgatagatc
     5341 gccctcagtt ccaggatcat agcattttta attagaaatt acggtttgat ttattataac
     5401 cataccgttc aagaaaatct tggcggaatt caagtaagtt atcgtccata atagcctgac
     5461 gtactttttt catcaagtta accaagaaat aaagattgtg gtagcttgtc aaacgaatac
     5521 caaaagtttc gtccgctttt agcaagtgac gaatgtaggc acggctatag ttttgacaag
     5581 tgtagcagtc acagtcatga tcaagtgggg taaaatcttc agcgaatttg gcatttttaa
     5641 ccacaaggcg cccctcacta gtcatacagg tcccattacg ggcaatacgc gttggcaaga
     5701 cacagtcaaa catatctaca ccacgaatca caccatcaat caagctatct ggtgctccca
     5761 ctcccatcag gtaacgaggt ttattttctg gtaagagggg agtcgtaaag tcaaggacgg
     5821 cattcatttc ttcatggctc tccccaacag ctaaaccacc aatagaataa cctgggaaat
     5881 ccatagccac caaatctgcc gcagactgac gacgaaggtc ctcaaatcca gctccttgca
     5941 caattccaaa taatccttgg tcatgaggac gacgatgggc ttttaagcca cgttctgccc
     6001 aacggctagt acgttcaatg gattttttca cgtaatcata aggttggtaa aattgcgggc
     6061 actcgtcaaa actcatcatg atgtctgagc caaggttatt ctgaatggaa atggcttttt
     6121 cgggtgatag aaacattttt gagccattca agtgattttt gaaagtcact ccttcttcag
     6181 tgatgtttcg tgaatcggct aaagagtaaa cttgaaaacc acccgaatcg gttaagattg
     6241 gctgatccca gttcataaac ttgtgcaaac caccagagcg agcaatcaac tcatctcctg
     6301 gacgcaacca gaggtgataa gtgtttgata aaataatccc tgatccaatt gcttttaact
     6361 cttctggaga ctgtgtttta acagtagcct gagttcccac tggcataaac attggtgtcg
     6421 gaaaggttcc gtgaggggtg ataatttcgc ccgagcgtgc accggtgtgc ttttctgttt
     6481 tgataaggcg atacttaatc ggataatctg tcatgtgctt tcttccttgc tatcaagata
     6541 aacagtcttg agcttttttg atctgcctga gtttccatca taatgaaggg cttcaagatg
     6601 acatgttgtt ctagcgccta tcattttatc aaaaaatcca taatttgtca tgctttccca
     6661 aaaaagtata gtcaaaataa tggttagctg tctcattttg ttttatggta taatgaaata
     6721 aaggagtctg ttatgtcaat taaagcaatc aaaggccagg ctagagacac gttaaaaaat
     6781 ctctctggca agtatttact atttttaatt ccaacccttc tctttatgtt tcatttcggt
     6841 attgagattc atcaaggtta cgtcctatct agtggtattg aagtctcgct agcggctagt
     6901 tatttcccat tactactagg acttatcctt agccttttca ttttatcagc atcctttaca
     6961 atgattgatg ttgttaggca ttttcgtcag aaagtttctt ttgccgaatc aacaacagcc
     7021 ttctcaaaag aattctttgg gaacctgctg gttttagcga tcactaagtg gctattcttt
     7081 ctcatctggt cactaatttg gttttttggc ctctttattt tcctttccgg actttcagcg
     7141 tttttggtca atgctaaatc aggtagctca acagtcattt cactgatctt tttactattt
     7201 ggagcagttt tgtccttaat tggttttggt atttatatca accgttatta cgcttatagt
     7261 ctatcagaat accttctcta cgataaggtt aaagagggga cttatctagg agctatagcc
     7321 gtcattgaaa caagtgtagc tatgatgaaa ggttataaat ggaagctttt tttcctacaa
     7381 cttagcttca ccggttggtt tctactgaat attgttactt ttgggttact taatatctat
     7441 cttttaccat attttacaac agccaatgtc attttttatg atcaactcaa gaaacgtttc
     7501 aaagacaaag atgacccaat tgaaggagaa catttaagcc ttcatcagct taataaaaag
     7561 cctactccta tgatgtatga cgatcaaaaa gactaaataa atcctccatc cataaaaata
     7621 gcccttgaac tgcaccccaa aagttagaca caaaatctaa cgattggggt gctatttttt
     7681 tatgaaattt aatcaagaaa cgaaagttaa gatttatgag ttacggcaaa tgggagagtc
     7741 cattaaatcc atatcaaaaa agtttgatat ggcagaatcc gatctcaaat atatgattcg
     7801 cttgattgat aggtatgggg taaccattgt tcaaaaatgt aagaataatt attattctcc
     7861 agaactgaag caagagataa taaatgaagt cctgattgac ggccaatctc agaaacaaac
     7921 atccttagat tatgctttac caacttctag tatgctctca aggtggatag cgcaatacaa
     7981 gaaaaacggt tatactattc ttgaaaaacc aagagggaga ccgagtaaga tggggcgtaa
     8041 acgtaagaaa aatttggaag agatgacaga ggttgaacgt cttcagaagg aattagaata
     8101 ccttagagcg gagaatgctg tgctaaaaaa gctgagagaa taccgcttga gggacgaagt
     8161 aaagctcaaa gagcaacaga aatcattcaa gcattaagga atcaatttcc cttagagatg
     8221 ctacttgaga tccttgattt atcacgctcc acctattact atcaagtgaa gcgactagct
     8281 caaggagata aggatataga actaaagcat gtgattcgag agatttatga tgagcataaa
     8341 ggtaattacg gttatcgtcg tattcatatg gagttgcgta accgaggatt tgtggtcaat
     8401 cataagaaag tt
//
LOCUS       DAUGOH010000054         8107 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUGOH010000054 DAUGOH010000000
VERSION     DAUGOH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8107
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.054"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            16..195
                     /locus_tag="VH957_001545"
     CDS             16..195
                     /locus_tag="VH957_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8559439.1"
                     /translation="MLTYDEFKQAIDNGYITADTVMIVRKDGQIFDYVLPGEPVRLWE
                     VATEEKVEGVMRELW"
     gene            1025..1594
                     /locus_tag="VH957_001546"
     CDS             1025..1594
                     /locus_tag="VH957_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEQ8559440.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVATFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            1595..3547
                     /gene="gyrB"
                     /locus_tag="VH957_001547"
     CDS             1595..3547
                     /gene="gyrB"
                     /locus_tag="VH957_001547"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEQ8559441.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEIIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            3915..5639
                     /gene="ezrA"
                     /locus_tag="VH957_001548"
     CDS             3915..5639
                     /gene="ezrA"
                     /locus_tag="VH957_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEQ8559442.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(5771..6229)
                     /locus_tag="VH957_001549"
     CDS             complement(5771..6229)
                     /locus_tag="VH957_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEQ8559443.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
     gene            6462..7769
                     /gene="eno"
                     /locus_tag="VH957_001550"
     CDS             6462..7769
                     /gene="eno"
                     /locus_tag="VH957_001550"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEQ8559444.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
BASE COUNT         2565 a         1329 c         1712 g         2501 t
ORIGIN      
        1 ataaggaggt aatctatgct aacatacgac gagtttaagc aagcgattga caatggatat
       61 atcacagcag acacagttat gatcgtgcgt aaagacggac agatttttga ttatgtgtta
      121 cctggtgagc ctgtaagatt gtgggaagtt gcgacagagg agaaggtgga aggagtgatg
      181 agggaattgt ggtgaaaagg gtgcaaaaaa ggggcaaaac ggattaaaaa tgaaactatt
      241 ttaaactttt tactataata attacctttt aaatcaacac ttgaactatt gtgaaccatt
      301 gtgtacaata gtagtagatt ccggcagggg tcattattgt cactgaaaaa gcctttacat
      361 caaaggcttt tttgtattac tcaattaatg ttaggagcac aaaagaggca gttcgattat
      421 taaccaattc ctccctattt acagatgtat ggctataaat ggacaatctt aagttagggt
      481 ctgagtgact aaacctgtcc ctaaccactt ttggtggtaa tcctttttca gctaaaagcg
      541 aaatgtgcga gtgtttgaat aagtgagtat ggtaatcacc ataaattttt aggcgcttat
      601 tgatgtgtgc atttaaaatt ggtaaacctt ttgaatatgg aaagctgtta gcactctgct
      661 tgtgattaat ctatcgtatg ttaaaagtga catttaaatt aaatcatttt ttattatttc
      721 aaaaggattt atcatattgg aaaatagcgg tgcttctatt ggcattttac tattgacagg
      781 aatttccctg ccttttgtct cctaaagaag atcagctttg atttctaact tgattagagt
      841 gggcttggta ctgtttatga attatcagtg catactttct ggagatcaaa aaggaaagga
      901 gcagctaaag aggtgtatgt gttaccatta gaggaataga acatcgcaag actcgtttat
      961 tcagtcatta cgatacctgt tttatttggg aaataactat aatattaagt gaatttgtga
     1021 tataatgaaa ggtatgaatt atcaagatta tatatgggat ttgggaggta ccttactcga
     1081 taattacgag ctttcaaccc aagcttttgt ccaaacgcta gcttttttca gccttccagg
     1141 agatcacgat gctgtttacc aaaaattaaa agaatcaacc gctatcgctg tggcaacgtt
     1201 tgctcctaat gagccagaat ttttgcatgt gtataggcta agagaagcag acaaattggc
     1261 acaacccatt tggtgtttgg gagctaaaga aattttggaa aagatagcga cttcaggttc
     1321 gcgaaatttt ttaatttctc atcgagattg tcaggtgaac caacttttag agcaagctgg
     1381 gttgttaatc tattttacag aagtcgtgac agcttcaaat ggctttgctc ggaaaccaaa
     1441 tcctgaaagt ttgttttatt taaaagaaaa gtatgatatt aatagtggat tagtaattgg
     1501 agatcggcta attgataaac aagcaggaca agcagcgggt tttaatacct tgcttgttga
     1561 cggtagaaaa aacctattgg agatagtaac gtagatgatt gaagaaaata aacattttga
     1621 aaaaaaaatg caagaatacg atgccagtca aattcaggtt ctagaagggc tggaggctgt
     1681 ccgaatgcgt ccagggatgt atattggctc gacagctaaa gagggtttgc atcatttagt
     1741 ctgggaaatt gttgacaact caattgacga agcattagca ggttttgcct ctcatattaa
     1801 agtctttatt gaagcagata attccattac agtagtagac gatggccgtg gaattccagt
     1861 tgacatccaa gccaagacag gacgtcccgc cgttgaaaca gtttttacag tcttacacgc
     1921 aggtggtaaa tttggcggag gcggctataa ggtttctgga ggactacatg gtgtagggtc
     1981 atctgttgtt aatgctttat caacacaatt agatgtgcgt gtttataaaa acggccaaat
     2041 tcattaccaa gaatttaaac gcggggctgt tgtagcagat cttgagatca ttggaaccac
     2101 tgatgtgact ggaacaacgg tacactttac acccgatcca gaaattttta ctgaaacgac
     2161 tcagtttgat tacagtgttt tagcaaaacg tattcaagag ttagcctttt tgaatcgtgg
     2221 tttaaaaatt tccattacag ataagcgctc aggtatggaa caagaagaac atttccatta
     2281 tgaaggtgga attggttctt atgttgaatt tttaaatgat aaaaaagatg ttatctttga
     2341 aacgcctatc tatacagatg gtgaattaga aggtattgca gttgaagtag ccatgcaata
     2401 cacgactagc tatcaagaaa cagtcatgag ttttgctaat aatattcata ctcatgaagg
     2461 tggaacgcat gaacaaggct ttagagcggc tcttactcgg gtcatcaatg actacgctaa
     2521 gaaaaataaa attcttaaag aaaatgagga caatttgaca ggagaagatg ttcgtgaagg
     2581 tttgacggcg gtaatttctg ttaagcatcc aaatcctcaa tttgaaggtc aaaccaaaac
     2641 aaaattgggc aactcagaag tggttaagat cactaatcgt ctctttagtg aggcctttca
     2701 acgttttctt ttggaaaacc cacaagttgc tcgtaagatt gtggaaaaag ggattttggc
     2761 ttctaaagct agaattgcag ctaagcgagc ccgcgaagtc acccgcaaaa aatcaggctt
     2821 agaaatttca aacttacctg gaaaattagc agactgttcg tcaaatgatg ctaaccaaaa
     2881 cgaacttttc atcgtcgaag gagattcagc gggtgggtcg gccaaatcag gtcgtaaccg
     2941 agagtttcaa gctatcttgc ctattcgcgg taaaattttg aacgtggaaa aagcaactat
     3001 ggataagatt cttgccaacg aagaaattag aagtctcttt accgctatgg gtacaggttt
     3061 tggtgcagac tttgacgtgt caaaagctcg ctaccaaaag ctggttatca tgaccgatgc
     3121 cgatgtggat ggcgctcata ttagaacctt gcttttaact ttgatttacc gctttatgag
     3181 gcctgttcta gaagctggct atgtttacat cgcccagcca cctatttatg gtgttaaggt
     3241 cggtagtgag attaaagagt atattcagcc aggtattgat caagaagacc aattaaaaac
     3301 agctcttgaa aaatatagta ttggtcgttc aaaaccaact gttcaacgtt ataaaggtct
     3361 tggggaaatg gatgaccatc aactttggga aactactatg gatcctgaaa atcgtttgat
     3421 ggcgcgtgtg acagttgatg atgccgcaga agcagataaa gtatttgata tgttaatggg
     3481 agatcgtgtt gaaccaagac gtgatttcat tgaggaaaat gcggtttata gtacactgga
     3541 tatttagtca cctttttagt ttcacaagga atctgctacc aaagaggacg aattgactaa
     3601 aaatcatgat gcatgatgcc aacagctttg ttagttagta cgtcttcatc ttgagggaca
     3661 gcgttaatgc ataggtattg agaccgcccc tttataccta tgttagtcct tattaagaaa
     3721 gccgtgtgag tcactggtac gagattgttg aattagtcaa atatattttg aaatgcattt
     3781 taaagtatgt tataatcgta atgttatagt gtattttaaa taaaatttta ataaaaggcg
     3841 attgaggaat ttcagttttt agttattact ggaacaatgt tgataaatcg tgtctaaata
     3901 ataaggagat tcagatgtca agcggaatta tcttgctgat tgtggctata gtcctactag
     3961 tgattatcgc ctatctagtg ggtgtcatca tacgaaagcg taatgattcc ctaattacca
     4021 gtctagaaga acgaaaacag gccttgtttg ctttgcctgt taatgatgaa attgaagaag
     4081 taaagtcact tcatttgata ggacagagcc aaacctcttt tcgggaatgg aatcagaaat
     4141 gggtagactt aactgtaaat tcgtttgcag atattgaaaa tcatattttt gaagctgaaa
     4201 atttgaatga tacgtttaat tttattcgcg ccaagcatga gattaatagc gttgaaagtc
     4261 agcttaatct tgttgaagaa gatatcgctt ctattcgtga ggcacttaat atcttaaaag
     4321 agcaagaaga aaaaaatagt gctcgtgtca cccatgctct tgatttatat gaaaagctcc
     4381 aagcttctat ttctgagaat gaagataatt ttggttcaac tatgcctgaa attgacaaac
     4441 agatgaaaaa cattgaaact gaattttcac agtttgtcgc actcaactca tcaggtgatc
     4501 ctgtagaagc ttctgaagtt ctggatagag cagaagagca tactattgct ctagggcaga
     4561 ttacagaaca gattccagct attgtggcca agttggaaga tgattttcca gatcagttag
     4621 atgatttgga aacaggatat cgccgtttac ttgaagaaaa ctatcatttt ccagaaaaaa
     4681 acattgaggc acgttttcag gagattcgtg agtctattcg tgctaattca tcagagttag
     4741 ttacacttga cttggatcgt gctagagaag aaaacacgca tattcaagaa cgcattgatt
     4801 ctctttatga agtctttgag cgcgaaattg ccgcttataa ggtagctgct aaaaatagta
     4861 agatgctacc tcgttaccta gcacatgtga aacgtaataa tgaacaactc aaagatgaaa
     4921 ttgcacgttt atcacgtaaa tatattctaa gtgaaacgga aagtctgact gttaaggcat
     4981 ttgagaagga tattaaagag atcgaagaca gtacacttgc tgttgcagaa caatttggtt
     5041 tacaagaaaa accattttca gaactgcaag tgacttttga acgcagtata aagacgctta
     5101 ctaatgtcga gtcaggtcaa atggatgttt ttgcagcagt taaagatatt gaaaaaattg
     5161 aatcacaggc acgccataac cttgatgttt atgttactca gcttcatatg attaaacgtt
     5221 atatggaaaa acgtcacttg cctggaattc cacaagactt tcttagtgct ttctttacaa
     5281 cgagttcaca gttggaagct ttgatggatg agcttagtag aggacggatc aatattgagg
     5341 cagtgtcacg tttgtcggaa gttgcgacgg ttgctattgc taatctagaa gatttaacct
     5401 atcaagtggt tcaaaatgct accttgactg aacaattact acaatattct aatcgctatc
     5461 gttcttttga agcaggagtt caaagtagtt ttgaacatgc tttgagactt ttcgaagtag
     5521 aaaatgatta tcaggcttct tttgatgaaa tttcttatgc tcttgaaaca gttgaacccg
     5581 gggtaacaga tcggtttgtt aactcttatg aaaaaacacg agagcacatt cgtttttgat
     5641 acttgaaagt cgtgatattc tcacgacttt ttattagctt tttggaccaa tacgtgtttt
     5701 tgactaaaat cttcttttta atgatcaaaa gaagaagtag taacagtgtt ttttgctatt
     5761 gagaggatag ttattttttc aaaaatcttt tccaaaagga tttggttttt tcaggagttt
     5821 gtttgctaag ttgatcgttt tttgtctgct ttaagatgac ttctaaacgt gtttccttca
     5881 gatttattgc gtggtcggta tgaaggataa acgcaaaagg tgaagtcata tgcgtttctg
     5941 taataatagt aacaggtaaa tggttttctt ttgctaattt catatagagt atttgaagtt
     6001 gaggtgccag cttggaagag atttttaagt gtaaaggttg atagactaac tgaaggctcg
     6061 gtaattctct tttcaaatag tcttttactg ttttagtttg agcttcgtct aataaagcac
     6121 ttaaaacgac tcgttcagca tacgttccta gatagtagcg ttgctgctca ggatttaatc
     6181 ttctttctcc ccaggctcct tttaatagct tatcttctaa attagtcata gataccctcg
     6241 cttctttata ataataatag tttctttatt atatcgattt ctacaataaa ataccaattt
     6301 gaaaattttc ggtaaatgtg ttaaaaaaca agaaagaaag tgatttttct tgcaaaaaac
     6361 aaaggaagct tttcatgaga ttgcttttta agttgattaa aggcctagtt tgtggtatta
     6421 tgaacatgta aaatattaaa actcataagg agagtattac aatgtcaatt attactgatg
     6481 tatacgctcg cgaagtcctt gactcacgcg gtaacccaac acttgaagta gaagtttata
     6541 cagaatcagg tgcattcgga cgtggtatgg ttccttcagg agcttcaact ggtgaacatg
     6601 aagccgttga acttcgtgat ggtgacaaat ctcgttacct tggtctaggt actcaaaaag
     6661 cagttgataa cgttaataac attatcgctg aggcaatcat cggttacgat gttcgcgatc
     6721 aacaagctat cgaccgtgca atgatcgctc ttgacggtac tcctaacaaa ggtaaacttg
     6781 gtgctaatgc tattcttggt gtttctatcg ctgttgctcg tgcagctgct gactatcttg
     6841 aagtgccact ttacacttac cttggcggat tcaacactaa agttcttcca actcctatga
     6901 tgaacatcat caacggtgga tcacactcag atgccccaat tgcattccaa gagttcatga
     6961 tcatgccagt tggtgcacct actttcaaag aaggtcttcg ttggggtgct gaagttttcc
     7021 acgctcttaa gaaaattctt aaagaacgcg gacttgttac agctgtaggt gacgaaggtg
     7081 gatttgctcc taaatttgaa ggaactgaag acggtgtaga aactatcctt aaagctattg
     7141 aagcagctgg ttacgaagct ggtgaaaacg gcattatgat cggttttgac tgtgcatcat
     7201 cagaattcta cgacaaagaa cgtaaagttt acgactatac taaatttgaa ggtgaaggcg
     7261 ctgctgttcg tacatctgca gaacaagttg attaccttga agagttggtt aacaaatacc
     7321 caattattac tatcgaagat ggtatggatg aaaatgactg ggatggttgg aaagttctta
     7381 ctgaacgcct aggcaaacgt gttcaattgg ttggtgacga cttctttgtt acaaacactg
     7441 aataccttgc tcgtggtatc aaagaaaatg cagctaactc aatccttatc aaagttaacc
     7501 aaatcggtac tttgactgaa acgtttgaag ctatcgaaat ggctaaagaa gctggatata
     7561 ctgccgttgt atcacaccgt tcaggtgaaa ctgaagattc aacaatcgct gacatcgcag
     7621 ttgcaacaaa cgctggccaa atcaaaacag gttcattgtc acgtacagac cgtattgcta
     7681 aatacaacca attacttcgt atcgaagatc aacttggtga agttgctcaa tacaaaggta
     7741 tcaaatcatt ctataactta aaaaaatagg cggtaagaca gaaatcggtc attcgtagaa
     7801 tgcgatttcg tcgtcgcacc tccgtcaggc tgactaggtt ggtcacgaca aaaggagtga
     7861 acatccagtc agctacgacg caaaagttaa agaatagaaa gcttgggaaa atcccaagct
     7921 ttttgctttc taaatagtaa aaatttactg tgggctaatt tatcctgagt taatgattcg
     7981 tgagaaaaac ttaacaactt gttaaaaaac tttggttctg ataatacagg accaaagttt
     8041 ttttatttag taaaaacgtc gtggtatagg tttgtccagg tattacatat ttcaaagtag
     8101 tatctag
//
LOCUS       DAUGOH010000055         8042 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUGOH010000055 DAUGOH010000000
VERSION     DAUGOH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8042
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.055"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            61..927
                     /locus_tag="VH957_001551"
     CDS             61..927
                     /locus_tag="VH957_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEQ8559445.1"
                     /translation="MKMKKKFFLLSLLALSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            938..1873
                     /gene="pstC"
                     /locus_tag="VH957_001552"
     CDS             938..1873
                     /gene="pstC"
                     /locus_tag="VH957_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEQ8559446.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1863..2750
                     /gene="pstA"
                     /locus_tag="VH957_001553"
     CDS             1863..2750
                     /gene="pstA"
                     /locus_tag="VH957_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEQ8559447.1"
                     /translation="MNAKKVDKVATGTLYIIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSTMTAAK"
     gene            2766..3569
                     /gene="pstB"
                     /locus_tag="VH957_001554"
     CDS             2766..3569
                     /gene="pstB"
                     /locus_tag="VH957_001554"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559448.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            3582..4340
                     /gene="pstB"
                     /locus_tag="VH957_001555"
     CDS             3582..4340
                     /gene="pstB"
                     /locus_tag="VH957_001555"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8559449.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            4408..5061
                     /gene="phoU"
                     /locus_tag="VH957_001556"
     CDS             4408..5061
                     /gene="phoU"
                     /locus_tag="VH957_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEQ8559450.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5266..7803
                     /locus_tag="VH957_001557"
     CDS             5266..7803
                     /locus_tag="VH957_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEQ8559451.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQPTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
BASE COUNT         2444 a         1404 c         1644 g         2550 t
ORIGIN      
        1 aatatgtggc acttagtttc tacatatata ccttttattt ttacgaatag gaaataaata
       61 atgaaaatga aaaaaaaatt ctttttgtta agtcttttag ccctatcaac tttcttttta
      121 tccgcatgtt ctagctggat tgataaaggc gagtcaataa ccgctgtagg atcaacagca
      181 ctacaaccct tagtagaagc agtagctgat gaatttggaa gcagtaatct aggtaagact
      241 gtcaatgttc aaggtggtgg ttcaggtaca gggttgtctc aagttcaatc aggagctgtc
      301 caaattggaa atagtgatgt ctttgcagaa gaaaaagatg gtattgatgc ttctaaatta
      361 gttgatcatc aagtagctgt tgcaggactt gcagttattg ccaatcctaa agtcaaggtt
      421 tccaatctca gtagtcagca gttgcaaaag attttttcag gagaatatac caattggaaa
      481 caagttggag gagaagatct tgcgatttca gtgatcaacc gagcagcaag ttctggctca
      541 cgagcaacct ttgacagtgt tatcatgaaa ggggtcaacg ctaaacaaag tcaagagcaa
      601 gactccaatg ggatggttaa atcgattgtt tcacaaacac caggtgccat ttcttacctt
      661 tcctttgcct acgttgattc atctgttaaa tctttgcaat taaatgggtt taaggcaaat
      721 gctaagaatg tggctacaaa tgattggcca atctggtcct acgaacacat gtacaccaaa
      781 gataaaccaa cagggttgac caaggaattt cttgattata tgttttcaga tgaagtacaa
      841 cagaacattg ttacacatat gggatatatt tcgataaatg atatggaagt ggtcaaatct
      901 catgatggaa aagtaacaaa aaggtaatgg aggaattatg gaaaatcagg aattggctaa
      961 aaaattagcc tcaccatcaa agaattcaag acttgaaacc tttggccgca ccattacgtt
     1021 tttgtgtctg gctttgattg tttttatcgt tgcgatgatt ctgatcttcg ttgctcaaaa
     1081 agggttgtca accttctttg ttgacaaggt taatcttttt gatttcttgt ttggaaagga
     1141 gtggcaacca agtgtgaaaa atgcggccgg cattccttat cttggtgctc tgccaatgat
     1201 tacaggatcc tttttggtta ccattttatc tgctattatt gccaccccat ttgccattgg
     1261 cgcagccgtt tttatgactg aaatctcacc taaatatggc gctaaattat tacagcctgc
     1321 ggttgagctt ttggttggaa ttccttcggt tgtttatggg tttatcggtt tgcaagtgat
     1381 tgttcctttt atgcgctcta tctttggtgg cacaggtttt ggaatcctat ctggggtctg
     1441 tgtcttgttt gttatgattt taccaacagt gacttttatg acaacagaca gtctgcgggc
     1501 ggtgcctcgt cattaccgcg aagcgtctat ggctatggga gcaacacgtt ggcaaaccat
     1561 ttggcgtgtt gtccttaatg cagctcgtcc aggaattttt accgctgtta tttttggaat
     1621 ggcgagagct tttggagaag ccttagccat tcaaatggtt gtcggtaact ctgctgtaat
     1681 gccaagttca ctaacgacac cagccgcaac cttaacgtct gtcttgacaa tgggtattgg
     1741 taacacggtt atgggaacgg tccaaaataa tgtgctttgg tcccttgccc tagtcttatt
     1801 attaatgagt ctggccttca attcccttgt caaattaatc acgaaagaaa gaaagagaaa
     1861 ttatgaacgc taaaaaagtc gataaagtag caactggtac tctttatatc attgctggaa
     1921 ttattgtagc tattttagct tccttaattc tatatatcct tgtccgtggc ttgccacaca
     1981 tcagctggtc ctttttaaca ggaaaatcgt cttcgtacga agctggtggg ggaattggta
     2041 tccaattgta taattccttc ttcctattga ttgttacctt gattatttcc attcctttat
     2101 caactggagc ggggatttac ttggctgaat atgccaaaaa agggcctgtt accaacttta
     2161 ttagaacctg tattgagatt ctgtcttccc taccatctgt ggttgtaggg ctctttggtt
     2221 acttgatttt cgttgtgcag tttgaatatg gcttttctat tatttcaggg gctcttgctt
     2281 tgacggtctt taatcttcct caaatgaccc gtaatgttga agatagttta ctgcatgttc
     2341 atcataccca aagagaagca ggattagctt taggcctgtc acgctgggaa acggtttttt
     2401 atgtggttat cccagaagct ctcccgggaa tggtaacagg tattgtctta gcttcaggtc
     2461 gtatttttgg tgaagcggca gcgcttatct atactgctgg tcaatcagca ccagctctgg
     2521 attggtcaaa ttggaatcca cttagtgtta ctagtccaat ctctattttc cgtcaatctg
     2581 agacccttgc tgttcatatt tggaaagtca atagcgaagg gacaattcca gatgctactc
     2641 ttgtatccgc aggaagtgca gcagtgctat taatttttat ccttattttc aacttttcag
     2701 ctcgctttat tgggaagaaa cttcattcta caatgacagc agcgaaataa gatattggag
     2761 aaatcatgac agaatacaat tggaatgaac gtcatatcat cacttttcct gaagaaacgc
     2821 ttgctctagc taccaaggat ttacatgttt actatggtgc gaaagaagct atcaaaggga
     2881 ttgatatgca gtttgaaaaa cataaaataa cagccttgat tggtccatct ggttgtggca
     2941 aatcaactta tcttcgtagt cttaaccgca tgaacgatac cattgatatt gctcgggtta
     3001 caggtgagat tctttatcag ggcattgatg ttaatcgaaa agacatgaat gtttacgaga
     3061 ttcgcaagca cttaggaatg gtttttcaaa gacccaatcc tttcgctaaa tccatttata
     3121 aaaacattac ctttgcccat gaaagagctg gtgtgaaaga caaaaaagtt ttagatgaaa
     3181 ttgttgagac ttcactgaaa caagccgcgc tttgggatca agttaaagat gaccttcaca
     3241 aatcagcctt caccttatca gggggtcagc aacaacgctt gtgtattgct agagccattt
     3301 ctgtcaaacc tgatattcta ttaatggatg aaccagcctc tgcccttgac ccgattgcaa
     3361 cgatgcagct ggaagaaacc atgtttgaat tgaagaagaa ttacacgatt attattgtga
     3421 cccacaatat gcaacaagca gctcgtgcca gtgattacac tgccttcttc tatttaggca
     3481 acctcattga atatgataag acacgtaata ttttccaaaa tgcgcaatgt cagtcaacaa
     3541 acgactacgt ttcagggcac tttggttaga aaggtaatat gatgacagaa cctattttac
     3601 agatcagaga cctttctgtt tactacaatc aaaagaaaac gttaaaagat gtctctttgg
     3661 acctttatcc aaatgaaata acagctttaa ttggtccttc tggatctggg aaatcaacgc
     3721 tcttgcgttc tatcaaccgt atgaatgatt tgaatcctga agtaaccatt acaggctcta
     3781 tcgtctataa cggacacaat atttatagtc caaggacaga tacggttgat ctacgcaaag
     3841 aaattggtat ggtattccaa caacccaacc catttccgat gtctatttat gagaacgtgg
     3901 tttacggcct tcgtttaaaa ggtatcagag ataaatcaat cttagaccat gctgttgaaa
     3961 gctctcttaa aggggcttcc atttggaatg aagtcaaaga tcgtttacat gattctgcgg
     4021 ttggcttatc aggcggacag caacagagag tttgcatagc tagagttctt gctaccagcc
     4081 ccagaataat ccttttagat gaacctacct cagctcttga tcctatctca gctgggaaaa
     4141 ttgaagaaac attattgtta ttaaaaaaag attatacact ggctattgtg acccgctcaa
     4201 tgcagcaagc ctcacgttta tcagatcgaa caggtttttt cttggagggt gacttacttg
     4261 agtgtggtcc tacaaaagcc atgtttatga atcctaagcg caaagaaacc gaagactata
     4321 tttctggtaa atttggttga gaaagacgta tatggttgac ccctctgtgt ttttattata
     4381 atgactagat tgtaggaaga aaaaatcatg ttaagaacga aatttgaaga agaattagat
     4441 aaattgcata accagtttta ttcaatggga acggaagtat tggcacaaat caataaaact
     4501 gttcgtgcct ttgttagtca tgatcgtgaa ttggccaaag aagttatcga agaagatgac
     4561 actattaata attttgagac aaagcttgaa aagaaatcgc tggaaattat tgccctacaa
     4621 cagccagttt cgaatgatct tagaatggtt attactgttt taaaggcatc aagtgatatt
     4681 gaacgtatgg gtgaccatgc tgcttcgatt gccaaagcca ctattcgtat gaaaggtgag
     4741 gagcgtattc cagtggttga agaacaaatc aaccttatgg gaaaagctgt gaaacagatg
     4801 gtagaagaag cccttaatgc atatatcaat gctgacgata caaaagctta tgaaatcgca
     4861 gcttctgatg agattatcga tcaatatttc cgtaatatcc aaaccttagc tgttgaagaa
     4921 atccgtaagt ctccagatgc tgtttttgca ggaaaagaat attttcaagt attaatgtat
     4981 ttggaacgta ttggtgacta tgctcgcaac atttgtgaat ggattgttta tcttaaaact
     5041 ggaaaaatta ttgaattata agaaattatg ctataatgag actgggaaac agcttgccag
     5101 tccctggttt tatacgaaat tgtgcaagtt agaaaatgaa ctaacaagaa aagttttctt
     5161 tgctgaatct gattttgtta ggttaacaaa tatatgtaga cagagatgat acttaggtat
     5221 catctgttga tctattatga tttgttatta gaattaagga gttatatgaa gacagtagaa
     5281 catctcatcg aaacatttgt gcctgaaaat tataacatct ttttagatat taatcgtcag
     5341 actaaaacat ttacggggaa tgttgcgatt aatggtgaag ctttagataa tcatgtggct
     5401 ttccaccaaa aagatttgga cattaagtct attttgctcg ataatgaagc tgttatttat
     5461 caagtggata acgacaatga agttgtgcgt gttgaattac ctgaaacagg aatgatgacg
     5521 cttgtcattg aattttcagg tagcattaca gataatatga caggtattta cccttcatat
     5581 tacactaaaa atggtgagaa aaaagaagtc atttcaactc agtttgaaag ccattttgca
     5641 cgtgaagctt tcccatgtat cgatgaacca caagcaaaag ctacttttga tttaagcttg
     5701 acctttgatc aagaaattgg tgagatagcg ttatcgaata tgccagaagt caatattgac
     5761 cgtcgcgagg agactggtct ttggacattt gatacgacac caagaatgtc atcttacttg
     5821 ctagcgtttg cgctaggaga acttcatgga aagactgtag aaagcaaaaa aggaacaact
     5881 gttggtgtgt atgcgacaac agcgcatcct cttagctcgc ttgatttttc attggatatt
     5941 gcagttcgtg ttattaactt ttatgaagac tattttggag tacattaccc aatcccgcaa
     6001 tcccttaata ttgcgcttcc agatttttca tctggtgcta tggaaaattg gggtttaatc
     6061 acttatcgtg aaatttattt attagtagat gaaaattcga ctgttcaaag ccgacaacaa
     6121 gtggcacttg taatcgccca cgagatagca caccaatggt ttggaaactt ggttacaatg
     6181 aaatggtggg acgatctgtg gttaaatgag agttttgcca acatgatgga atatgtctct
     6241 atcgaggcta ttgagccgtc ttggaaaata atagaagatt tccaaacagg cggtattcct
     6301 cttgctttaa aacgtgatgc tactgatggt gttcaatcag tgcatgttga agtcaatcat
     6361 ccagatgaga taaatacatt gtttgatcct gctattgtct atgcaaaagg tagtcgtttg
     6421 atgcatatgt tacgccgttt tattggtgat cgtgattttg ccattggctt acatcactac
     6481 tttgaaaaat atcaatatcg aaatactgtc gggcgtgatt tatggaatat tttatcagat
     6541 acttcaggca aagacgtagc tgcttttatg gatgcttggc ttgaacaacc aggttatcca
     6601 gttttaacag ctcgccttga aaacgatcaa ttgattttga gtcaaaaaca attttttatt
     6661 ggaaaaggtg aagaaaaagg tcgcctttgg ccgattcctt taaacactaa ttggcatggc
     6721 cttcctgaaa ctttgacaga ggcagaaatg gtcattccaa actttagtca attggcagca
     6781 gaaaatgaag gagctctacg tttcaatatt gataatacag ctcattacat tacagattac
     6841 caaggatcat tattagatgc cttagtcact gaacttgccc aacttgataa tacttctgct
     6901 ttacaagtta ttcaagaacg tcgtttattg gcagatagtg gcttgatttc ctatgctgaa
     6961 ttggttgact taattgctca attggacgat tctaagtctt atatggtagc agaagcggtt
     7021 cagcaagtgg tctctggttt gaaacgcttc attgatgaag gaagcttagc agaaaaatcc
     7081 tttaatcgct tggtaaccac catctatcaa gaagacttta atcagcatgg ttttgagaaa
     7141 aaagctgacg aatcagatga agatgagatg gtacgtcagg ttgccttggg ccgcttgtgg
     7201 ctagcagaaa atcagacgat tattgacgga ttgagaacta tttttgaagc atatcaaaac
     7261 aatattgcaa gtattccagc agctgttcgt cgcttggttt tagccaacca aatgaaatat
     7321 tttgaaacag atagcttggt tgatatttat tttgagactt atgtagcaac tactgataat
     7381 aatttacgca gtgatttaac ggttgctttt agtcaaacaa aacaaccaac tactattaga
     7441 cgtattcttg ttagtttaaa agataaagat attattaaac ctcaggattt atcttattgg
     7501 tataatgctt tgcttggaca aagctttact caagatatca tttgggaatg ggctagagaa
     7561 aattgggatt ggattaaatc tgcacttggt ggagatatga gctttgataa atttgttatt
     7621 tatccagcaa gtaactttaa aacaccaaaa catctagcag aatataaatc tttctttgaa
     7681 cctaagctag atgatatggc tattagccgt aatattacca tgggaattaa tgaaattgaa
     7741 gcacgtgttg ctttgatcac taaagaaaaa gaagcagtta ttgcagctct cagtcattac
     7801 tagaccataa gcaaaagagt tgggggactt tccagctctt ttttgtagtg agctagcttc
     7861 ctttcttagt tccgtctata actaagtgat tatctatagt ttaattcaaa aggagattgc
     7921 actttaaagc gaaggctatt agcctcttaa tacttttttt accaggtggt gaataagaac
     7981 aattataaat gatttaatca ttatgcttta aatgccttaa aggagtatta atattttagt
     8041 aa
//
LOCUS       DAUGOH010000056         7533 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUGOH010000056 DAUGOH010000000
VERSION     DAUGOH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7533
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.056"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            460..777
                     /locus_tag="VH957_001558"
     CDS             460..777
                     /locus_tag="VH957_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8559452.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
     gene            901..2799
                     /gene="mnmG"
                     /locus_tag="VH957_001559"
     CDS             901..2799
                     /gene="mnmG"
                     /locus_tag="VH957_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEQ8559453.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            2889..4865
                     /locus_tag="VH957_001560"
     CDS             2889..4865
                     /locus_tag="VH957_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEQ8559454.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            4862..5314
                     /gene="rplI"
                     /locus_tag="VH957_001561"
     CDS             4862..5314
                     /gene="rplI"
                     /locus_tag="VH957_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEQ8559455.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            5350..6711
                     /gene="dnaB"
                     /locus_tag="VH957_001562"
     CDS             5350..6711
                     /gene="dnaB"
                     /locus_tag="VH957_001562"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEQ8559456.1"
                     /translation="MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFY
                     KYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANA
                     EYYAKIVAEKAMLRDIIARLTDSVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFR
                     KISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTA
                     FVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNV
                     TIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPEN
                     RQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADI
                     VAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQF
                     EER"
     gene            6728..7000
                     /locus_tag="VH957_001563"
     CDS             6728..7000
                     /locus_tag="VH957_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEQ8559457.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
BASE COUNT         2500 a         1148 c         1562 g         2323 t
ORIGIN      
        1 attggaaatt cctagttata cttttatggt tttgttatcg gcgttcttac ttgtagactt
       61 agaaacaacg gtatctgtat tttactactt tagaagatat caaaaaatcg tatgataata
      121 ctgatgacat ttttatttct cgcctcgcta gattagacat agtgatactt ttgtaatcat
      181 tttaaaaaca ttacaataga ttgacagaga tgtaaaaaca ttgacattac tgtaaaggtc
      241 tgtgatgaaa tcaatattga caatcaataa tcattttttt aaaatagata ataacaatcg
      301 gaatgatggt caaagctcat gaaagttgta ggtttttttg tcctgcaatc ttctagggtt
      361 ttggcccttt ttatggttta gctctagaat tgagatggct aataggactg ggatttagaa
      421 tcactagagg tcagataact ttagtttacg agctagtgct tgattgttag aaatggtaag
      481 aattttttaa ctagagatgc agctgaccaa tattacacca ttggtggtac aagtttggta
      541 ggtgaaaaaa cgcatgaaac tgttttacgt gaaaccttag aggaagttgg tattcgaact
      601 aaggttaatc aactggcttt tgtggttgag aatcattttg atatcgatga tgttttctgg
      661 cataatattg aatttcatta tttggtaagc cccttagaag accctaaact agaaatgata
      721 gagaatgcaa gcgacaggtt tgtgaatgga ttccaatcaa tcaactggat caaatgaatc
      781 ttgtttctga gtttttacaa accgagttgg ctaaatggcc aggacatatt gttcgcattg
      841 aaggctaaac taaagcgtat gattttaaat gaatagactg aaataaagga ttttaaaaaa
      901 atgacacatg aatttacaga aagctatgac gtcattgtca taggtgcagg tcatgctggt
      961 gttgaagcca gtttggccac tagtcgtatg ggttgtaaaa ctttattggc aacaatcaac
     1021 cttgatatgt tggcttttat gccgtgtaat ccttctattg gaggatctgc caaagggata
     1081 gtggttagag agattgatgc tcttggcggc gaaatgggta aaaatattga taaaacctat
     1141 atccagatga aaatgcttaa tacaggtaag ggaccagctg tacgcgctct ccgagctcaa
     1201 gcagataaat ccctgtatgc gcgtgaaatg aaacatacgg ttgaaaaaca ggctaatttg
     1261 actcttcgcc aaacgatgat tgatgatatt ctagttgaag atggacgagt tgtaggtgtt
     1321 ttaacagcca caggacaaaa atttgcggct aaggcagttg tagtgacaac aggaacagct
     1381 ctgcgtggcg aaattatttt aggagaactc aaatattctt ctgggcctaa taatagtttg
     1441 gcatcagtaa ctttagcaga taatttaaaa aaactcggct tagaaattgg cagattcaaa
     1501 acaggaacgc ctcctcgtgt caaagcatct tctattaatt acgatcaaac ggaaattcag
     1561 ccaggtgatg acaaacctaa tcatttttca tttatgtcaa aagatgctga ctatctcaaa
     1621 gatcaaattc cctgctggtt gacttatacg aatcaaacta gtcatgatat cattaatcag
     1681 aacctttaca gagcaccgat gttttctggc attgttaaag gtgtaggccc tcgttactgc
     1741 ccatctattg aagataagat tgttcgcttt gctgataaag aacgtcatca acttttctta
     1801 gagccagagg ggcgtgatac agaagaagtg tatgttcaag ggttgtcaac gagtcttcca
     1861 gaagatgtcc aaaaagattt gattcattcg atcaaaggac ttgaaaaggc tgaaatgatg
     1921 cgcactggtt atgctattga atatgatatt gttttacctc accagctacg tgccacactt
     1981 gaaaccaagc taatttcagg actctttacg gctgggcaaa ctaatggaac ttctgggtat
     2041 gaagaggctg ctggccaagg acttattgct ggaatcaatg ctgctttgaa agttcaaggt
     2101 aagccagaac ttattttgaa acggagcgat gcctatattg gcgttatgat tgacgattta
     2161 gttaccaaag gaaccttgga accttatcga ttgttgacat cgcgagctga gtatcgtttg
     2221 attttacgtc atgacaacgc tgatatgcgt ttgacagaga ttggtcgcga cattgggttg
     2281 gttgatgatg agcgttggaa ggccttcgaa attaagaaaa accaatttga taacgaatta
     2341 aaacgtctga acagtatcaa attaaaacca gtaaaagcaa ccaacgatcg tgtgcaggaa
     2401 cttggtttta aaccattgac ggatgctatg acagctaaag aatttatgcg tcgcccagaa
     2461 attgattatg cgactgcagt ctcttttgtt ggtcctgcgg ctgaagattt agatgctaaa
     2521 atcattgaac ttttagaaac agaaatcaag tacgaaggct atattcgcaa agctttagat
     2581 caggttgcta agatgaaacg catggaagaa aaacgtattc ctgcaaatat tgattgggat
     2641 gctattgatt ctattgcaac tgaggcgcgt cagaaattta agaaaattaa tcctgaaaca
     2701 attggacaag ctagtcgtat ttcaggagtc aatcctgcgg acatcagtat cttgatgatt
     2761 tatttagagg gaaacggaaa agctcatcga aaatattaaa tggaaatgaa attgtaatct
     2821 caaagcaagt ggaagctctg tatttcaggg cttttttatg gtataatgtg tgcttaagag
     2881 gttataagat gaaaaaattt cgttttgaaa ccattcattt gattatgatg ggattgattt
     2941 tatttggact actggcactt tgtgtcagta ttatgcaatc aaaaatatta atattattag
     3001 ctatttttct cgttttgcta tttgttgttg ctcttttatg gtatcaaaaa gaagcttatc
     3061 aattatcaga cttagctcat attgagctct taaatgaaca aacagaagat aacctaaaaa
     3121 cgctacttga taatatgcct gttggagtag ttcaatttga tcaagagacc aacgctgtag
     3181 aatggtataa tccttatgca gaattaattt ttacaactga agagggtttt atacaaaaca
     3241 gtttgattca gcaaattatt acggaaaaac gtcgtgaaga tatttctcaa acatttgaag
     3301 tttctggtaa taaatacact tcttatattg atgtatcatc aggaattttt tatttttttg
     3361 atagctttgt gggaaacagg caattagctg atgctagtat gttaagaccg gttgttggca
     3421 ttatttcggt tgataattat gatgatatca ctgatgattt atcagatgca gatacctcaa
     3481 aaattaattc atttgtagct aacttcattg atgagtttat ggagtcaaaa cggatttttt
     3541 accgtcgtgt taatatggat cgctactatt tctttacaga ctttaaaaca ttaaatgatt
     3601 tgatggataa taaattttct gtcttagaag agtttcgtaa agaagctcaa gatgctcagc
     3661 gccctttaac actcagcata ggaatttctt ttggtgaaga aaatcatagc cagattggac
     3721 aggtagctct tgagaatctt aatattgcgc ttgttcgtgg tggtgatcag attgtcattc
     3781 gtgaaaatgc ggatcatacg aatccaattt atttcggggg agggtctgtt tctacagtta
     3841 aacgttcaag aacacgtacc cgtgctatga tgacagctat ttcagatcga atcaagatgg
     3901 tggacaatgt ttttattgtt ggacatagga aacttgatat ggatgcacta ggttcagctg
     3961 ttggtatgca atttttcgca ggtaacatta ttgaaaatag ttttgccgtt tacaatccag
     4021 atgagatgag tccagatatt gaaagggcta ttgagcgatt gcaggctgac ggaaagactc
     4081 gtctaatcag tgtttctcaa gcaatgggtt tagtgactcc aagatcactt ttagtaatgg
     4141 ttgatcattc taagatatct ttaacacttt ctaaagaatt ttatgaacag tttcaaaatg
     4201 ttattgtagt tgatcatcac agaagagatg atgattttcc tgataatgct atcttaactt
     4261 ttattgaaag tggagcaagt agtgctgcgg agctcgtcac tgagttaatt caatttcaaa
     4321 atgctaaaaa acgtttaaat aagatccaag ccagtgtttt aatggcaggt attatgcttg
     4381 atactaaaaa tttttctacg cgagtgacaa gtcgtacctt tgatgtcgct agttacttaa
     4441 gaagtaaagg aagtgatagt gttgaaattc aaaatatatc cgcaacagat tttgaagaat
     4501 ataagcaaat aaatgaaatt attttacaag gagaacgtct tggtgacagt atcattgtag
     4561 ctgcaggaga aaaaaatcat ctttatagca atgttattgc tagtaaagct gcagatacga
     4621 tactgtcaat ggctcacgtt gaggctagct ttgtattagt tgaaacagct tctcataaga
     4681 ttgctatttc agctagaagt cgtagtaaaa tcaatgttca acgtgtgatg gaaaaattag
     4741 gtggaggagg ccactttaat cttgctgcct gtcagttaac ggatatcagt cttccccaag
     4801 caaagcactt attattgaaa actattaata tgacaatgaa agaaacagga gaagtagaat
     4861 catgaaagtt atttttttag cagatgtaaa aggaaaaggt aaaaaaggag aaatcaaaga
     4921 ggtcccaaca ggctatgctc aaaatttcct tattaagaaa aatttagcta aagaagcaac
     4981 tagtcaaagc atcggtgaat taaaaggaaa acaaaaagct gaagaaaaag ctcaagctga
     5041 aatattagca gaagctcaag ctgtcaaggc tgttttggat gaggacaaaa cacgtgttca
     5101 atttcaagaa aaagttggtc cagatggacg tacatttggt tccatcacag ctaaaaagat
     5161 ttcagaagaa ttgcaaaagc aatttggtgt aaaagttgat aaacgtcata ttgttttaga
     5221 tcatcctatc cgcgccattg gtctaattga agttcctgtg aaattacata aggaagtaac
     5281 agctgagatt aaattggcta tcacagaagc ataatataaa aaacatcaca agatttggag
     5341 gttatgaggt tgcctgaagt agctgaatta cgagttcaac cccaagattt actagcggag
     5401 caatctgttc ttgggtcaat ctttatctca cctgataagc tgattgcagt gagagaattt
     5461 atcagtccag acgattttta taagtacgct cataaaatta tctttcgggc aatgattact
     5521 ctcagcgatc gtaatgatgc cattgatgca accactataa gaacaatcct agatgatcaa
     5581 gatgatctgc aaagtattgg tggcttatcc tatattgttg aactagttaa tagtgtccca
     5641 actagtgcta atgcagaata ttatgctaaa attgtagctg agaaagctat gttgcgtgat
     5701 attattgcta ggttgacaga ttctgtcaac ctagcttatg atgaaatttt aaaaccagaa
     5761 gaggttatcg ctggagttga gagagcttta attgaactca atgaacatag taatcgtagt
     5821 gggtttcgca aaatttcaga tgtattaaaa gttaattacg aggctttaga agcacgttct
     5881 aagcagactt caaatgttac aggtttacca actggtttta gagaccttga caagattaca
     5941 acaggtttac acccagatca attagttatt ttagctgctc ggccagcagt ggggaagact
     6001 gcctttgttc ttaatattgc gcaaaatgtg gggactaagc aaaaaaagac tgttgctatt
     6061 ttttctttgg aaatgggtgc tgaaagttta gtagatcgta tgcttgcagc agaaggaatg
     6121 gttgattcgc acagtttgag aacagggcaa ctcacagatc aggactggaa taatgtaaca
     6181 attgctcagg gagccttggc agaagcaccg atttatattg acgatacgcc cgggattaaa
     6241 attactgaaa tccgcgcaag atcacggaaa ttgtctcaag aagtggatgg tggtttaggt
     6301 cttatcgtaa ttgactactt acagttgatt acaggaacta aacccgaaaa tcgtcagcaa
     6361 gaggtttcag atatttcaag acagcttaaa atcctagcta aagaattgaa agtaccagtt
     6421 attgccctaa gtcagctttc tcgtggcgtt gagcaaaggc aagataaacg accagtttta
     6481 tcagatattc gtgaatcagg atctattgag caggatgccg atattgtagc cttcttatac
     6541 cgggacgatt attaccgtaa agaaggtgat gatgctgaag aagctgttga agataacaca
     6601 attgaagtta tcctcgagaa aaatagagct ggggcgcgtg gaacagtcaa actgatgttc
     6661 caaaaagaat ataacaaatt ctcaagtata gcccagtttg aagaaagata agaaagagag
     6721 acaaaaaatg agcgatgcat ttacagatgt tgcaaaaatg aaaaaaatta aagaggacat
     6781 aagagcccat gaaggacagt tagtagaatt aacccttgag aatggacgga aacgggaaaa
     6841 aaataaaatt ggtaggctta ttgaggttta cagttcactc tttatcattg agtatagtga
     6901 tagctctgat actccaggag caattgataa ttcttatgtc gaatcataca cctattcaga
     6961 tattttgaca gaaaaaacat taattcgtta tttagattga tttttgcctc atagaggctt
     7021 tttctttaca ataaattgat ataattatta gcgatagaag attattctgc ctgtattctt
     7081 tttattttga aaaaattcct ataaaagata atatttttag gttagattga aggaaaaaag
     7141 aggtcttcac catggttaag caaatgatct tagtactaag gttaaaagat tatcgtgaaa
     7201 taaagttttg acacaagtgt aattaataga ggaacttgaa gtatccggta aaactatctt
     7261 gaagtgaaaa aacgagtaga cctcccctga taaatacaat atactagcca tttcagagca
     7321 attaagagtt tccagtgaag tgcttttgat agagagctaa gaaaaaaaca gtcaaggttt
     7381 aagaactgca aattagcatt taaattattt tttgttgatg acagttgtct ttattaccat
     7441 aactataact tcttataata tagtcttctt attcatcagt ggtggctcgt ctcatatctg
     7501 accttaaaat attaaactga tcatcagatg ata
//
LOCUS       DAUGOH010000057         7523 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUGOH010000057 DAUGOH010000000
VERSION     DAUGOH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7523
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.057"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            91..1509
                     /locus_tag="VH957_001564"
     CDS             91..1509
                     /locus_tag="VH957_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8559458.1"
                     /translation="MDKKIQRFSCTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMI
                     VVKPEDQPRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATE
                     TITTNSRVLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVA
                     FSDEHDIWWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFI
                     DTYHLDLTYSHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWC
                     QKPYRKITVEDVKYVLSSHYQDTGYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRP
                     NKPQEIAAIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAAL
                     ADPHYNHHETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQ
                     TLLNKILFDASNLMTNRFSLSD"
     gene            1661..3208
                     /locus_tag="VH957_001565"
     CDS             1661..3208
                     /locus_tag="VH957_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEQ8559459.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPIYEF
                     TKGIVGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDTDAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTKKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGERKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            3359..4081
                     /locus_tag="VH957_001566"
     CDS             3359..4081
                     /locus_tag="VH957_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8559460.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMIENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKVGKTPKTEILS
                     FEQYQVTPYLSGLLEFDPDTEVFELERLRIADDMPLMFERSYIPAQLFQGLSIEHLKR
                     KPMYDLFAEDYQETIRLAEEEFYASIALDYEAGLLGIKKGDPVLHIIRKTYNDNNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            4100..5299
                     /locus_tag="VH957_001567"
     CDS             4100..5299
                     /locus_tag="VH957_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEQ8559461.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDS
                     FLKRVCNSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQRYLFESVASTDLVAAP
                     DYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQYNKA"
     gene            complement(5367..5627)
                     /locus_tag="VH957_001568"
     CDS             complement(5367..5627)
                     /locus_tag="VH957_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEQ8559462.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(5742..6683)
                     /locus_tag="VH957_001569"
     CDS             complement(5742..6683)
                     /locus_tag="VH957_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEQ8559463.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWMSQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            7077..>7523
                     /locus_tag="VH957_001570"
     CDS             7077..>7523
                     /locus_tag="VH957_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEQ8559464.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
BASE COUNT         2362 a         1392 c         1573 g         2196 t
ORIGIN      
        1 aagataagga ggtgctgctg gaattatgaa aatttttgta tccagttcaa tggatatttg
       61 atataatcgt cttaaaaagg aggtcgtgaa atggataaaa aaatacagcg tttttcatgt
      121 acaactatac tcgtcggtaa aaaggcatct tatgatggct caaccatggt tgctcgaaca
      181 gaagattctc aaaatggtga tttcacgcct aaaaaaatga ttgtggtgaa accagaagat
      241 caaccgagac attaccgttc ggtgcaatct tcctttgaaa tggacttacc ggacaatccc
      301 atgacttaca cgtctgttcc cgatgcgctt ggtaaagatg gtatctgggc agaagcaggc
      361 gtgaacgagg ctaatgtggc catgtcagca actgaaacca tcactaccaa ttctcgtgtt
      421 ttaggggcag atcctctagt agcttctggt attggtgagg aggacatggt gaccttagtg
      481 ctcccttata tccgttctgc gcgtgaaggg gttttgcgcc ttggtgccat tttagaagac
      541 tatggcactt acgagtcaaa tggtgtggct ttttcagatg aacatgacat ttggtggctg
      601 gaaacgattg gtggtcatca ctggattgca agacgggtgc cagatgatgc ttatgtcacc
      661 aatcccaatc aatttggcat tgatcatttt gaatttaaca atcctgaaga ttacctttgc
      721 tcagctgatt taaaggactt tattgacacg tatcacttag atttaaccta tagccatgag
      781 cattttaatc cgcgctatgc ttttggtagt caacgtgaca aagaccgtca ctataatacg
      841 ccacgtgctt ggatcatgca aaaattctta aacccagaaa ttgtgcaaga cccgcgcagc
      901 tttgcccttg cttggtgtca aaaaccttac cgtaaaataa cagtagaaga tgtcaaatat
      961 gtattgagta gtcactatca ggacacgggt tatgaccctt acggttcaga aggaactcct
     1021 gttagtaaga aagtctttcg ccctattggc attaaccgta ccagccaaac cgctatctta
     1081 cacattcgtc ctaataaacc tcaagaaatt gccgctattc aatggatggc ttatgggtca
     1141 atgccattta ataccatggt gccttttttc acacaggtga agactattcc agattatttt
     1201 gccaacactt acgaaaatgt gtctaccgac aatttctatt ggaccaaccg tctgattgcg
     1261 gctttggcag atcctcacta caatcatcat gaaactgatt tggacaatta cttggaagaa
     1321 accatggcaa aaggtcatgc catgttacat gctgtggaag cacagttatt ggctggtgaa
     1381 acagtcgatt tggaagagga aaatcaaaaa atgagtgact atgtgcaagg agaaacgcag
     1441 acgctgttga acaagattct ctttgacgct agcaatctaa tgaccaatcg tttcagtttg
     1501 agcgattaat agtgaagcta aggctgagca actgcttagc cttttttacg ataacttttt
     1561 aggaaaagta atcgcaaaaa gacaaaaact tggaaaaaaa atcaaagtat gctatactta
     1621 actggtcaat ttttaaccag ttaataacaa aggaggaatc atgaaaaaga aaattctttt
     1681 aatgatgagt ttaatcagtg tcttttttgc ttggcaactt actcaggcaa aacaagtctt
     1741 agcagagggt aaagtgaagg tggtgacaac tttctatcct atttatgaat ttacaaaagg
     1801 gattgttggt aatgatggcg atgtttccat gcttatgaaa gcaggaacgg aacctcatga
     1861 ttttgagcct tctacaaaag acattaaaaa aatccaagat acagatgcat ttgtttatat
     1921 ggatgacaat atggaaactt gggtttctga tgtgaaaaaa tcattgacat ctaaaaaagt
     1981 gaccatcgtc aagggaactg gtaacatgct cttggtagca ggagctggac atgaccatca
     2041 ccatgaggat gctgacaaaa agcatgagca taataaacat agtgaagaag gacacaacca
     2101 tgcttttgac ccacacgtgt ggttgtcacc ataccgtagc attacggtcg ttgaaaatat
     2161 tcgcgacagt ctttcaaaag cttacccaga aaaagcagag aacttcaaag ccaatgccgc
     2221 tacttatatt gaaaaattaa aagagcttga caaagactat acggcagcac tttcagatgc
     2281 taagcaaaag agctttgtga cacaacacgc agcttttggt tatatggcac ttgactatgg
     2341 cttgaaccaa atttctatta atggtgtcac accagatgca gaaccatcag caaaacgtat
     2401 tgctactttg tcaaaatacg ttaaaaaata tggcatcaaa tacatttatt ttgaggaaaa
     2461 tgcgtcaagt aaagtcgcaa aaaccctagc taaagaagca ggagttaaag cggctgtgct
     2521 tagtccgctt gaaggtttga ctaaaaaaga gatgaaagct ggccaagatt actttacggt
     2581 catgcgtaaa aaccttgaaa ccttacgctt aaccactgat gtggctggta aagaaattct
     2641 tccagaaaaa gatacgacaa agacagttta caatggttat ttcaaagaca aagaagtcaa
     2701 agatcgtcaa ttatctgact ggtcaggtag ctggcaatct gtttatccct atctacaaga
     2761 tggtacttta gaccaagttt gggactacaa ggctaaaaaa tccaaaggta aaatgacagc
     2821 agccgagtac aaagattact acactactgg ttataaaact gacgtggaac aaatcaaaat
     2881 caatggtaag aaaaagacca tgacctttgt tcgtaatggt gaaaggaaaa ccttcactta
     2941 cacatacgcc ggcaaagaaa tcttgaccta tccaaaagga aatcgcggag ttcgtttcat
     3001 gtttgaagct aaagaaccaa atgctggcga attcaaatac gttcaattca gtgaccatgc
     3061 cattgctcct gaaaaagcag agcatttcca cctgtactgg ggtggtgaca gccaagaaaa
     3121 attacataaa gagttagaac attggccaac ttactacggt tcagacttat ctggtcgtga
     3181 aattgcccaa gaaatcaatg ctcattaatc ttaactcact aagcaaatct tcttttaagt
     3241 aaggaggttt gctttttctt tgtggagtaa aaaaattaat aattctcaac attaatttga
     3301 cggacactta tgattataat atactttaag tggttataac aagttagagg tgaataagat
     3361 gccaaaagaa caaccactct atctacagat tgttgatgac ttggaagtga aaatcaaaaa
     3421 aagcatgata gaaaacgata agttgttgtc agaacgagaa ttaagtgacc tttacggtgt
     3481 tagtcgtatc acgattagac tggctcttaa ggaattggaa ttacgagact taatttataa
     3541 aaagcagggc aaggggactt atgtttcagg aatcaaagaa cctgtcactg atttatcaag
     3601 tacttacagc tttacagagc aaatgaaaaa agtggggaaa actcctaaaa cagagattct
     3661 ttcttttgaa cagtatcagg taacacctta cttgtctggt ctcttagagt ttgatcccga
     3721 tacagaagtt tttgaattag aacgcctaag gattgcagat gatatgccct tgatgtttga
     3781 acgatcctat attcctgctc agctttttca agggttaagc attgagcact tgaagcgtaa
     3841 gccaatgtac gatttatttg cagaggatta ccaagaaact attcgcctag cagaagaaga
     3901 gttttatgct agcattgcct tggactatga agcaggtctc ttaggcatta aaaagggaga
     3961 tcctgtctta catattattc gtaaaactta taatgataac aatatcttaa ttgaattgac
     4021 tttcagcatt gcaagggcgg atcagtttag gtaccgagta caacatcacc ctaatggtta
     4081 aggaattgga ggttaggaca tgtttacaaa aacgcaggaa gctttggagg ctcttggtgc
     4141 agctatcact accaaggaaa ttaaacaaga accccgttta tggcaagaaa ccatgacgtt
     4201 ttttgacgaa acaagagatt ctctggattc ttttttaaag agagtttgta acagcgctaa
     4261 cagaaataac gttcatgtca tctttacagg tgcgggtaca tctgagtaca tcggtaatac
     4321 catttgccct tacttgaaga aggtggggaa tcggcagcgc tatctctttg agagcgttgc
     4381 ttcaaccgat ttggttgcgg cgccagatta ttatcttgtt gaggaagaga cggtactatt
     4441 agtctccttt gctaggagtg gtaatagtcc agaaagtgta gcggctgtta acctggtcaa
     4501 tcaactagtg ccaaatagtt atcatttaac cattacctgc gccaaagatg gagaactggc
     4561 gaaaaaagca cagcaagatg agcgttctta cctttatttg atgcctgaag acgctaatga
     4621 tgctggtttt gccatgactg gtagttttac ctgtatgatg ctagcggctc ttttgatttt
     4681 tgatgatgct aacagtatag ctcagaaaga agcttatgtg actgatatga ttcttgctgg
     4741 gcaagctgtt attgaccaag aaagacggct acaagagcta gctgatttag gatttgaacg
     4801 tttagtttat ctaggttctg ctggtttagc caagttaacc caagaagctc aattaaaaat
     4861 gttagaattg acagctggac aagttgcgac cctctacgag tcctctatgg gctttaggca
     4921 tggtccgaaa tcttttatta atgaccgtac cttagtcatt ggatttgtca ataatgatgc
     4981 ttacgtcaga cagtacgatt tggacatgtt agaggaaatc caagcagatg gcattgccct
     5041 taaaatcttg gctctattgc aaggagggga tatcaacttt tcagaggacc aatttcgact
     5101 agacacccgt cacttattgc cagaagctta cttagctttt cccatgattt tagtcgcgca
     5161 gaccttggcc ctcttaacgg ccgttacatt aggaaattcc cctgacaccc catctgcgac
     5221 aggaacggtt aatcgtgtgg tcaaaggagt aacgattcac ccttacccga ctagtagtcg
     5281 tcaatacaac aaagcttaaa gcttttgtgc tagtaggcca aaagaaaaac cctcctgata
     5341 caggaaggtt ttttgtattg tcttgcttat tttgctgcgt ttgcgtcttt gagaccgtat
     5401 tttttgttga agcggtccac acgtccatct gcttgagtga acttttgacg tcctgtgtag
     5461 aatgggtgtg aatctgatga aatttccaca cggataagtg ggtaagtttc accttcaaac
     5521 tcaacagttt ctttagaagc ttttgttgag ccgctaagga actggtaacc tgtagttgta
     5581 tcaaggaaaa caactggacg ataatctgga tgaatgtctt ttctcatctt aaaaaattcc
     5641 tttctgccat gacacttgat gcatcatagt tattaactat tctagtgtaa caaaacttga
     5701 atgacttgac aaggcttttc tttccttatt ttttaaaaat cctaaatctc ttggcaaaca
     5761 gcgatgagtt ctcggaaaat agcttgattt tcttctaaat tagctgagtt ggctccgcta
     5821 gcaaggggat gcccccctcc accgtgacgc ttagcaatgc cattaataat cttttcttta
     5881 ctgcgcatac gcacacggta gttgccgtca gttaactcaa caaaaatagc ccaagcttga
     5941 acgttatcaa ttttaccagg agcacagaca atagcagagc tttctgctag ggtcacgtca
     6001 aaatgtttta aggtttcttg gctgacaagg acataagcag ccccactctc atcaattgtt
     6061 aaatgctcaa agacgtagct ttgcagcttt gctattttca aaggaaacga atccatttgc
     6121 cttgaaatcg cagcaaagtc gaactcgaaa tgtctgagtt ggctagcaat ggaaagggtt
     6181 ttactagtgg ttgaggcata aagaaatcgc cctgtatcac caacgatacc agtgtataag
     6241 agcttagcag ctttgtcaga gagagtaaga ttctgactaa aggcaaagtc tgcaatgatt
     6301 tcacttgcgc tagaagcgct tgtgtccaca taatagaagt caccatacac atcatcgttg
     6361 ggatggtgat caatcttaat taagcactgc cccagtgtgt agcgctcatc atcaatcctt
     6421 ggtcgattcg ctgtatctgt aatgatgacc aaagcctctt tgtagtcttt gtcagtcacc
     6481 tgatccattt ggctcatcca agctaaacta ggctcatcaa aaccagtcat taaaaccttt
     6541 ttgtctggga aattttgtgc aataatttct ttcaagccgg cctgactacc aagagcatca
     6601 gggtcaggat tttgatggcg atggataata atagtttggt gagcttttat tttatctaaa
     6661 attgtttcaa aagttgttat catgctttaa tctttctttt tcaaaaagag gaaaataacc
     6721 gtttaacata gtcttcaaaa aacggtttgt gtcataagga ggtgtgcgtt atgttcagtg
     6781 gctaatgcta gaatttttta agattgtcaa agaccataaa ttgacatttt atctgaaaat
     6841 catatcctat tttattatag cataaaagta agctctagat aatggtaaat taatctagga
     6901 agaaaagagg ttagttatca gctatgatac tatcaaagct agtcttgcaa atgcaagtga
     6961 aaaaatagtt tttaagtgtt ttaagtaatc atatcaacct tctcgttaaa gaattagtgc
     7021 ttttcctaaa aaagtgtgct aaaataaaca tagtttagta attttgggag gaatttatgg
     7081 cattagcaaa aatcgtttat gccagcatga cgggaaatac tgaagaaatc gctgatatcg
     7141 ttgcaaataa attgcaagaa ttgggccatg atgttgacat tgatgagtgc acaacagttg
     7201 acgcttcaga gtttgagaat gctgatatcg ctgtcgttgc gacttatact tatggtgatg
     7261 gtgacttacc agatgaaatc gttgattttt acgaagattt acaagattta gatttagaag
     7321 gtaaaatcta tggcgttgtc ggctctggtg acacttttta tgactatttt tgcaaatctg
     7381 ttgatgactt ttcagagcaa tttgcgctta ctggtgccat caaaggtgca gagccagtca
     7441 aagtagattt ggcagcagaa gatgaagaca tcgatcgttt agaggccttt gcagagcaac
     7501 tctcacaggc tgttaataat cta
//
LOCUS       DAUGOH010000058         6845 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUGOH010000058 DAUGOH010000000
VERSION     DAUGOH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6845
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.058"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(115..2433)
                     /gene="pcrA"
                     /locus_tag="VH957_001571"
     CDS             complement(115..2433)
                     /gene="pcrA"
                     /locus_tag="VH957_001571"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEQ8559465.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSAEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
     regulatory      2748..2834
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            2962..4284
                     /locus_tag="VH957_001572"
     CDS             2962..4284
                     /locus_tag="VH957_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEQ8559466.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNESVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFVLM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     gene            4404..5639
                     /locus_tag="VH957_001573"
     CDS             4404..5639
                     /locus_tag="VH957_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEQ8559467.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEEIFDNVAKNLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQ
                     ITPIAKRQLHPTHYRIVKM"
     gene            complement(6009..6782)
                     /gene="cfa"
                     /locus_tag="VH957_001574"
     CDS             complement(6009..6782)
                     /gene="cfa"
                     /locus_tag="VH957_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEQ8559468.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTVLMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATINKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKV
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
BASE COUNT         1928 a         1351 c         1277 g         2289 t
ORIGIN      
        1 taaaatgcaa ctgatatgct cctaaaactt aaaatttttt aacttttata tgatacagaa
       61 atctaaaaaa atgagcttcc tactcactta tatagtagga agctcatttt tttcttattt
      121 tttctcaata ggagcaacac ttgctagtaa tttctttaaa ccaacttctg gaaatttgat
      181 tttcaattcc atcgtttttc cggagcctga aacctcaagc acagtcccgt ctccccattt
      241 tttatggtga gcgatatcgc caatctgcca agtgacctct tctgcagagc tattagaacc
      301 aaacggtaaa actgagctag ttgaagctga tggtatcgta tgtgcctgca ttggctgtgc
      361 tgattgtctt acttgagcct gggcctttcg agcttgtaag gcttctgata agctcatccc
      421 ttgtccaaac tgtgtgtgtg tttcagtaga aaaacgcaca ccaaatgaag attgtgctgg
      481 tcttgccaat cctttataag agagtagttc ctctgaaatt tctttcaaga agcgtgttgg
      541 acggttataa ctacttttac caaagagggt tctggtgttg gcattggtca taaagagaac
      601 ttcttcagct cttgtgattc cgacataagc taaacgtctt tcttcttcca attcatctgg
      661 atcttcagag gcacgtgata agggaaagac accttcttcc ataccaatta agaaaacaac
      721 agggaactcc aagcctttgg cagcatgtag ggtcattaag gttacttcag cagcttctgc
      781 ttgggaatca tctgtatcag caatcagtgc taaatcgttt aaaaaacgtc ccaagcgatc
      841 aacaccggtt tcgtcttctt cttgagaggc acttgactcg tcaaaatttt tggtaacaga
      901 taagaattct tcgatatttt cgatacgggc ttggctttcc aatgtatttt gcaggcgtaa
      961 gctatctaaa tagcctgttt tttctaacaa agcttctgct aagtcggtga tactcatctg
     1021 atctaggtct tgacgtagct gaccgagaat attggccaag tccatgatag cttgtgctgc
     1081 tttacctttc aagggggaca tcaatagatt tgaagctgct tctaataaag actggtcact
     1141 ctcataggca aactgacgca gtttatcaag cgttcctgga ccaacacctc gtttaggctc
     1201 attcacaatc cgctcaaaag aaatattatc agcagggtta gcaacaatgg ttaaataggc
     1261 aatcaaatcc cgaatttctt tacggctgta aaacttggtg cctccaacca tggtgtaagg
     1321 aatattggat tttaagagtg cttcttcaat ggtccgagat tgggcattgg tacggtataa
     1381 aacagcgaaa tctttgaagt tttttccaag ctcttgactc atattgctaa tggttgaggc
     1441 cacaaatact gcctcatctc gctcatcatt tgccctgtaa taaaccagtt gttccccatc
     1501 cgcattttgt gtccaaagtt tcttaggacg gcgattacgg ttattgttaa tcacgtcgtt
     1561 agctgcttgc agaattttct tggtagagcg atagttttct tctaaaagca ctaccttagc
     1621 atctgggtaa tctttttcaa aatcaagaat attttgcatg tcagctcccc gccaaccata
     1681 gatagactga tcagcgtctc caacaacgca aatattttta aagcgagaag ctagcaattt
     1741 aattagctga tattgagcat ggttggtatc ttggtactca tccacatgaa tgtattggta
     1801 acgctgctgg taataagcta acacgtcagg attagcgtca aacaggcgta gcgtcatcat
     1861 gattaaatca tcaaagtcaa gtgcttcgct acgtcgtaat tcttcctgat aagctttgta
     1921 acacctcgct acgatttgac tatacatatc agcagcctgt gcctcgtatc ccttttcatc
     1981 aagcaaatca tttttagcgt ttgaaatagt tcctaaaata gaacgttcat tccacttttt
     2041 agggtctata tttaattgtt ttaaaatgcg cttcatcaac gttcgttgct cacctggatc
     2101 cacgattgtg aagtttcggt tgtaaccaat gtgatcagcc tcacgacgca gaatccgtac
     2161 acacatggag tgaaaggtag caattaaggt atctttagta gctggattta aggccaaggc
     2221 tctttctttc atttcacgcg cagccttatt agtaaaggta atagctaaaa tattccaagg
     2281 attgacaaat ttttcatcaa ttaaataggc aatacgatgg gtcagtaccc ttgttttacc
     2341 agaaccagcc cccgccataa tcaataaggg gccttcagtt gtttgaacag cttgtgcctg
     2401 ccgatcattc attccattta ataaaggatt catgctttct ccttaatctc gttcagtgac
     2461 atctctttta tcaaccttaa aattatatca tgtttccaag aaaaatagca aagaagaccc
     2521 caaaagtaaa gagattcctt ttttctagtt taggttcaga tatttaaaaa taatagcgat
     2581 ttcttaaagc attcctcatt tttttgctat tttggttgac ttcattcgtt ttttgaggta
     2641 tgatagtcct aatttaataa accgaatgat gtcatgcagg agaagaattt ttttcgccga
     2701 aggagttata ctctcaggtg ttcagttttt gaacgggact gtttgatgga cggacttctg
     2761 gagagacctt attaggcgcc gaaggggcaa ggcatactgc tcaatctctc aggcaaaagg
     2821 acagaaggta aaatacaaac accattaaga acagtcttag tcttttttgt gtttgctgtt
     2881 ttatcattgc ttcagaagtt gtctcaaaga aagagatagc ttttttcttt tggcgtcttc
     2941 gatgactttt aggagagaaa gatgatagca ctcgttaaat taattgataa ccttgtttgg
     3001 ggaccgcccc tcttaatttt attggttggg acggggattt accttaccag tcgtttagga
     3061 ttaattcaaa tcttaaaact accaagagcc tttaaactca ttttttcaga tgacgaagga
     3121 catggagata tttcatcctt tgctgctctt gcaactgccc ttgccgctac tgtcggaact
     3181 ggtaacattg ttggggttgc cactgctatc aagtctggtg gtcctggagc gctcttttgg
     3241 atgtgggttg ccgctttttt tggaatggcc actaagtacg ctgaaggggt actagcgatt
     3301 aaataccgta caaaggatgc caacggtcat atttctggtg gtcctatgta ctatattgtt
     3361 aatggcatgg ggacaaaatg gaaaccctta gccattcttt ttgcgggttc agggatccta
     3421 gttgccctat ttggaatagg aacctttgct caagtgaact cgatcacctc gtctttaggt
     3481 catagctttg gcttatcccc acaaatggtc agtattgttt tagctatctt tgtggctgcc
     3541 attatttttg gtggcattca ttccatttcc aaagtggctg aaaaagtcgt tccttttatg
     3601 gctatttttt atattctatc tagtttagca gttattttta gtcactacca gcagctactt
     3661 cctgttattc gtttagtctt tcaatcagcc ttcactccga cagctgctat tggaggcttt
     3721 gctggaagtc tcatgaagga tgccattcaa aaaggaattg cacgcggtgt cttctccaat
     3781 gagtctggac taggatctgc acctattgct gcagcagcag ctaaaaccaa tgaatccgtg
     3841 gagcagggcc tgatctccat gacaggaact tttattgata cgattattat ctgtacccta
     3901 accggcctat ctattttagt aacaggccaa tggactgggc agctcgaagg ggctcctctg
     3961 acccaatctg cctttgccac tgtgtttgga aatttaggga cttttggcct aaccttttcc
     4021 ctagttctct tcgcctttac aacgatttta ggatggagtt attatggaga acgctgcttt
     4081 gaattcctct ttggcattac acatctcacc tacttccgta ttgtctttgt cttaatggta
     4141 ggcctaggag gcttccttaa gttagaactg atttgggttt tggctgatat tgtcaatggt
     4201 ttaatggcac ttcctaacct gattgccctc ctagctctct cgccagttgt tattttagaa
     4261 accaagcatt actttattaa gtaaacatga cgttagtact acccagttat acctagtctt
     4321 cttctgccaa gttcaagacg ctaggctttt ttcttaagcc cctttttatg gtataatata
     4381 aagttgaaat caaaggagtt attatgacac aggatccgat tgcaaattta aaactagcca
     4441 gaaagggccc aatcgttagt attattgtct acttgtcgct tagtgttgcc aaattattag
     4501 ctggttattt gttaaatgca agttccctta ttgctgatgg atttaacaat ttatcggata
     4561 ttgtgggaaa tgtagccctg cttattggtc ttcacttagc tagccaacca gccgatgcca
     4621 atcataaatt tggtcattgg aaaattgaag acttatccag ccttgtcact tcttttatta
     4681 tgtttcttgt aggtttccaa gtactgattc acacaattaa aagtatcttt agtggtcagc
     4741 aagttgatat tgaccctctt ggggcgattg tcggtatcgt ttcagctttt gttatgttag
     4801 gggtttatgt ctttaacaaa cgtctttcca aacgtgtaaa atccagtgcc ttagtcgctg
     4861 cttctaagga taatctagct gatgctgtta cttctatcgg aacatcaatt gctattatag
     4921 cagcttcttt gcatttacca gttatcgatc atatagctgc tatgatcatt acgttcttta
     4981 ttcttaaaac agcttttgat atctttatgg aaagttcgtt tagtttatct gatggatttg
     5041 atagccgtca tttgaaaaaa tacgaaaaag ccattttaga aatccctaaa attgtcgccg
     5101 ttaagtctca acgagctagg acctatggta gcaatgtcta tcttgatatt gtacttgaaa
     5161 tgaatcctga tctttcagtc tatgaaagtc actctattac agagaaagtg gagcagttat
     5221 tgagtgacca attttctatt tatgacattg acattcacgt tgagcctgcc atgattcccg
     5281 aagaagagat ttttgataat gtcgccaaaa atctctaccg ctacgaaaaa ttaattttga
     5341 gtaaggttcc tgactatgac cactacattg ctaagtcttt ccaactgatt gatgcgaatg
     5401 gccaaacagt taactatgaa caatttttga accaagaaat ttattatcca agtaacttca
     5461 accattttca gattgaatcc attagtcaaa aaacgatgtt ggtaacttac caattaaatg
     5521 gtaatcaaca taccagtatt tggaggcgtc atgaatcttg gtccttactc ttccaccaaa
     5581 ttacccctat cgctaagaga caattacatc ccacacacta ccgtattgta aaaatgtaaa
     5641 aacatcactt ctcttataac ataactatac ttcatgatat tcctaaagcg attcctagtc
     5701 ccaaaatgat aagtgaaata gttaaaaaaa tccctacaat ttgtttttaa acagatcata
     5761 gggatttttt taagaataca cgttttcata ttcaatctta ttagtttagg aggttaaaca
     5821 agattcaata gtgacggttg aacaatacct taaattggca catcatgtta aaggcaaaaa
     5881 gggctacagg tgactcattg tttatgagaa catcatctca aactctacaa tggtaagata
     5941 tttaaaatct ttacctattc tatatcctaa tataatcatc tacctataca acacattact
     6001 tatacactct atgacttaag agctgtttcc aaagcatttt gcacagcaat aacttcatcg
     6061 tcaacttgtt gaacagtggt tgtcggattt agttggacac caaccgcatg tgtgatagct
     6121 ttgttaagtc tattgtaaac gtcaaatggt ttgatcccta aaaccttttt atctctttct
     6181 aaacgagtgt tccaaatagc tttatttagt ttagctttag tatagatagt agcacggtct
     6241 gttggctgta aatcaggata attgataact ttttcctcaa gtgctttaat ttcttgtact
     6301 tgaactttga tagcgtcaac agatgcaaat ggatctataa tacgaatgac taatttagta
     6361 atagcaaacc ccatatcagt atgcgctttt tctactttat gagttaattg ggttgtggaa
     6421 aatacgattg ctttgatagc atctgataat gcttctactc ttgccccaat tgaactaaaa
     6481 tcatagatcg tttcagtatt gaagcgtata gaactcttca tgtgatcaac agcatcgata
     6541 gctttgttaa tagtagcctc aatatcagta cctttagctt catgtttaat agcttctaat
     6601 tgttgatgcc cctcatcaag cttttgcact agagcatctc tttgaagatt cgcttggttg
     6661 ttattcatta aaacagtatc gggatttgaa gcatcatcag ctaaaactga gtgcgtcata
     6721 gttgaaaata aagctaatcc agcaacaact gttgaaagac agagaaggtg tttgggtttc
     6781 atattattcc tcctgaatat aataaaccta tttaaatagt taagtgaagt taaattaatt
     6841 tataa
//
LOCUS       DAUGOH010000059         6654 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUGOH010000059 DAUGOH010000000
VERSION     DAUGOH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6654
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.059"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            125..2323
                     /gene="nrdD"
                     /locus_tag="VH957_001575"
     CDS             125..2323
                     /gene="nrdD"
                     /locus_tag="VH957_001575"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEQ8559469.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            2505..2651
                     /locus_tag="VH957_001576"
     CDS             2505..2651
                     /locus_tag="VH957_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559470.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRLQELKARFLEKSK
                     KQDN"
     gene            2680..3615
                     /locus_tag="VH957_001577"
     CDS             2680..3615
                     /locus_tag="VH957_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8559471.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGQAVLYSDVKELPKASLDGVFIHAATSAHAELASVFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKELSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIAASQLSYGELKVELPKD"
     gene            3624..4118
                     /locus_tag="VH957_001578"
     CDS             3624..4118
                     /locus_tag="VH957_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8559472.1"
                     /translation="MEIRRPTLEDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLASQGVPAIQYVAFDEKNQALGFLNLRLRLNASLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSCAISKNITTILVTCDETNVASRAVIVANGGVLEDSRGGTERY
                     WIEE"
     gene            4133..4747
                     /gene="nrdG"
                     /locus_tag="VH957_001579"
     CDS             4133..4747
                     /gene="nrdG"
                     /locus_tag="VH957_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEQ8559473.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(4921..5652)
                     /gene="yaaA"
                     /locus_tag="VH957_001580"
     CDS             complement(4921..5652)
                     /gene="yaaA"
                     /locus_tag="VH957_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEQ8559474.1"
                     /translation="MLTFLIPTAKEMMIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFHYHPDLSTDHEFVYIKKEA"
     gene            complement(5694..6551)
                     /locus_tag="VH957_001581"
     CDS             complement(5694..6551)
                     /locus_tag="VH957_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8559475.1"
                     /translation="MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLVLNHFLTRGISLEGAAD
                     HGYSEAIYLSDPEDNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKR
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKNARLHGLAILQEDSSSFTTEDEEGI
                     CVNVILGQD"
BASE COUNT         2015 a         1106 c         1525 g         2008 t
ORIGIN      
        1 aagttttatt gtttatcaga aaaagtaatc taatatcaat atattgtgtt cgagcaaaaa
       61 acttgacaca atatattgat ttttttagtt gtcgtgatat aatagttccg taaggagatt
      121 tgatatggta agtttagaag aagacaaggt gactgttcaa cctgatatta aagtgattaa
      181 acgagatggt cgccttgtta attttgatag tacaaaaatc tatagtgctt tattaaaagc
      241 aagcatgaaa gtaactcgga tgtcgccact tgttgaggct aaattagagg ctatttctga
      301 tcgcattata gcagaaatta ttgagcgttt tccaactaat atcaaaattt atgaaatcca
      361 aaatattgta gagcataagc ttcttgcagc taatgaatat gctattgcaa aagaatacat
      421 taattatcgt actcagcgtg actttgcacg ttcacaagca acagatatca atttttctat
      481 tgataaatta attaataaag atcaaacagt tgttaatgaa aatgctaaca aagatagcga
      541 tgtttttaat actcaacgag atttaactgc tggaatcgta gggaaatcga ttggtttaaa
      601 aatgttacct tcgcatgttg ctaatgctca tcaaaaagga gatatccatt accatgattt
      661 ggattacagt ccttatacac cgatgacgaa ctgctgttta attgacttta agggcatgtt
      721 agccaatggc tttaaaattg gtaatgctga agtggaaagt cccaagtcta ttcaaactgc
      781 aacagctcag atctcacaga ttattgcgaa tgtagcatca agtcagtacg gcggatgcac
      841 agctgatcgc attgacgagt ttttagcccc atatgcggag cttaacttta aaaaacatat
      901 ggctgatgct aagaaatgga tcgttgagac taagagagaa agctatgctt ttgaaaagac
      961 tcaaaaagat atttatgatg cgatgcagtc tttggagtat gaaattaata cgctctttac
     1021 gtctaatggt caaacaccat ttacttcttt aggatttggt ttggggacgt cttggtttga
     1081 acgtgagatt caaaaagcta ttttgaccat tcggattaat ggtcttggta gtgaacatcg
     1141 cacggctatt ttccctaaat taattttcac ggttaaacgt ggcttgaatt tagaaccaga
     1201 ttcaccaaac tatgatatta agactttggc tttagaatgt gcgactaagc ggatgtaccc
     1261 ggatatgtta tcttatgata aaattattga tttgacagga tctttcaaat ctccaatggg
     1321 atgccgctct ttccttcaag gctggaaaga tgaaaatggg caagatgtga cctcaggccg
     1381 tatgaatctt ggggttgtca ccctcaattt acctcgcatt gccatggaat caaatggcga
     1441 tatggataag ttttgggagc tgtttaatga gaggatgcta attagtaagg atgctttaat
     1501 ttatcgtgtc gaacgtgtca cagaagcaaa accagcaaat gcccctattc tttatcaata
     1561 tggtgctttt ggaaaacgtt tggagaagac agggaatgta aatgatctct ttaagaatcg
     1621 tcgtgcaaca gtctctcttg gctatattgg tctttatgaa gtggcatctg ttttttatgg
     1681 tggtcaatgg gaaggtaatc cagatgctaa agcttttacc ttgtcaattg tcaaggcaat
     1741 gaaacaggcc tgtgaggatt ggtcagatga atatggttat catttctctg tttattcgac
     1801 tccatcagaa agtttgacag atcgcttttg tcgtttagat acggaaaaat ttggcattgt
     1861 gacagatatt acggataaag aatactatac aaattctttt cactatgatg tgcgtaagag
     1921 tccgacacct tttgaaaaat tagattttga aaaagattat ccagaagcag gtgcttcagg
     1981 tggttttatc cactactgtg agtatcctgt tttgcaacaa aatccaaagg ccttggaagc
     2041 ggtttgggac tatgcttatg atcgtgtggg gtatttggga accaatacgc ctattgataa
     2101 atgctataat tgccaatttg aaggcgattt taccccaaca gaacgtggtt ttacttgccc
     2161 aaactgtggc aataatgacc ctaaaacagt tgatgtggtc aaacgtacat gtggttactt
     2221 ggggaatcct caggcccgcc caatggttaa cggtcgccat aaggaaatct ctgcgcgtgt
     2281 aaaacatatg aatggttcta ctataaaata cccaggcctg taaactcaag ctggggaaga
     2341 gcccttttga tggaaatatg atatgcttaa aaggttgctt catgcaagca atcttttatt
     2401 gtttaatggt ttcttagcaa ttgtgagata agaataacta atccaaaacg actaattagc
     2461 tgttagcaat cggactataa gaagaaagag ataaggaaga aataatggga aaatatcaat
     2521 tagactataa aggaatgcag caggtagaac gctttcatga gaagcattct aaaaaaaaga
     2581 cggataaaaa atcccgcctt caagaactta aggctcggtt tttagagaag tcaaaaaaac
     2641 aggataacta aagtatccag taaagaaaga aggctgagta tgcttaatat tgggattgtg
     2701 ggactaggtg ctatttcaca aaaagcctat ttaccatata tgagacagct gagtgacatt
     2761 acttggcatc tatcaacgcg gaatgcagca gtacgtcagc aggtcggtca gttatttgga
     2821 caggctgttc tttacagtga tgtcaaggag ttgccgaagg caagtttaga tggcgtcttt
     2881 attcatgcag ccacatcggc ccacgcagag ttggctagtg tgtttttaaa tcagggaatc
     2941 ccagtcttta tggataaacc tatagctgac aattacctga tgacaaagaa cctctatgac
     3001 ttagccaaag aaaatcagac ttttctgatg gcaggattta acaggcgttt tacacctcgt
     3061 gtcaaggaat tgtcaagttt gtcaactaag cgtaaagtgg ctgttgaaaa aaatgacttg
     3121 aaccggccag gagacatgac ttttaagctc tttgatttct ttatccatcc tttagataca
     3181 gccttattct tgacagaagg gaccttgcta aaagggcatt ttcaatacca tctggaagca
     3241 ggcttactga gtcaagttat ggtaaccttg atgaccgaaa gcatgacgac tacagcttct
     3301 atgaatttac aatcagggag tcgccgtgag gtaatggaag ttcaacgggc tgaagaaact
     3361 tatcatttag agaacttaga cgagttatct atttataaag gtactgaaaa aagggtgctt
     3421 ggctttgctt cttgggacac caccctgcac aaaagaggtt ttgaaacaat gatcgatgcc
     3481 tttttagaag ctattagcac aggcgtcaat cctgtcagcc ctgagtctag tcttttaagc
     3541 cactggattt gtcaacagat tgctgcctct cagctttctt atggagagtt aaaggtagag
     3601 ttgcctaagg attaggaatt aatatggaaa taagacgacc gactttggaa gataaagatg
     3661 ctgtattgtc aatgattaac gaatttttag agcagaaaag tgctacagat gggttatggc
     3721 attttaacgt caatgacttt aactatgaaa catggttgga agattccttg cgacaggaaa
     3781 tgggtttggc cagtcaagga gtgcctgcta ttcaatacgt cgcatttgat gagaaaaatc
     3841 aagctttggg atttttaaac cttaggttac gtttaaatgc ttcattactt gaaaaaggtg
     3901 ggcatattgg ttactctgtc cgtcccagcc agcgtgggaa aggttatgcc aaggagatgc
     3961 ttaaacaagc tgtcagctgt gcgatttcca agaatatcac gacaattttg gtaacttgtg
     4021 atgagactaa tgttgcaagc cgagcagtta ttgtggctaa cggcggtgtc ttggaagata
     4081 gtcgaggtgg aacggaacgt tattggattg aagaataaag aggcgataag tgatggcaga
     4141 aaagtgttgg aataatccta agccaaagga atggcaggca gaggagttaa gtcaaggccg
     4201 gattattgac tataaggctt ttaactttgt tgatggtgaa ggggttcgta attcccttta
     4261 tgtgtctggt tgtttattcc attgcaaggg gtgttataat gctgcgactt ggtcttttaa
     4321 ggcgggaatg ccttatacgc aagaacttga agagcagata atgacggatt tggcacagcc
     4381 ttatgttcag ggactgacac ttttaggtgg agaacccttt ttgaatacgg gtatcttaat
     4441 tcctctgatt aagcgtattc ggcgtgaatt gccagaaaaa gatatttggt cttggacggg
     4501 ttatacttgg gaagaaatga tgcttgaaac accagacaaa ctggaaatgt tgtccttaat
     4561 tgatattctg gtagatggtc gttttgatat cacaaaaaag aacctcatgt tgcaatttag
     4621 aggctcttct aaccagcgaa ttatcgatgt tcaaaagtct ttggctgcta aagaagtgat
     4681 tatctgggat aagttaaacg atggggacca aacctttgaa caaattagtc gggaggattt
     4741 gctttaagaa gctgacttat ccacatgatt tttttgaaaa ggtcatgtga aaacaggtcc
     4801 tttaagggtg gattggggag aaagtaattg ttattccctg gttttcccca cattatcctc
     4861 atagttatcc acaggttgtg tataagttgt agaattgtga ataaagacta aaaaagaggc
     4921 ctaggcctct tttttgatat agacaaattc atgatctgtt gataggtctg gatggtagtg
     4981 aaaaccagca aagacaaggc ttttaaggct gtcaacagtt tggcaattat tttccataca
     5041 ggcagtgaga aatgcacctc gtgccttttt tgaaatggtg gaatgggttt tgaattggcc
     5101 ctctttttct gccataaact tgggacttat ccacaattgt ttacagtctt tggaaaagac
     5161 atcgtcaaat tcactggata aaagggaaat cacttgggga tgctctttgg caaactgatt
     5221 ataacagggc cgccagtaag acttgaggct ttgtccttca atttttattc tggtgtgaaa
     5281 atcatggcgg tgctctgcga taggatgatt agcgggaatg ataccgtaaa aggatgaggt
     5341 gatgtaaact tgctgggtga ggtaagcctg ttcttgggta gtgagcttat cgcgcttgat
     5401 atggcggtac ataaggccat tgaacagttg gtaggcaggg taagccaagc tttgttgaga
     5461 ggccatgtct tgccagcgtt gctgttcttt tttagctgcc tcttctttga tacgatagga
     5521 tttggccaag tcctccgtgg tcatagctgc catgattttt aaaatggctt ggctgtcttg
     5581 tggaaggagg tgtgggtgag attccttagg gatcatcatt tcttttgcgg ttggaattaa
     5641 aaaggttagc atagtgttat tgtagtaaag ttacttgctt tctgtcaaga aaactagtct
     5701 tgtccaagga tgacgttcac acagatacct tcctcgtctt ctgtcgtgaa agaagaagaa
     5761 tcttcttgta aaatagctag gccgtgtaat cttgcgtttt tcagagtagc tgaaaaaagc
     5821 aggggcgtct caatgtgaat ggtcaagaag gctaagcctg gggcaccttc ttggtgtttt
     5881 ttgaggtaag gggctgacca gtgattgaat gcaaggtgat gatggtagtt ccctgaagca
     5941 atccagctag cacttggaat ggtcatttta tcgcctaaat caaaaacctt ttgatagaga
     6001 agtgaagaag ccagagcatt tttgacactc agatggacat ggccaatgcg tgtgtcttga
     6061 gctagtaaaa agcgcttggg gatatctgtc aactgctcca atatgctttt ggtatccgtg
     6121 ggctcagtca caccaataat ttgaccattg tcgcggatat cccaatgctc aacagctttg
     6181 tcatgataaa tttcaatccc attgtcctca ggatcgctga ggtagatagc ttcgctatag
     6241 ccgtgatcag ctgctccttc taaagagata cctctggtta agaaatgatt gagaacaagt
     6301 cccaagctat gacgatcagg aactaaaaag gctgtgtgat aaagaccata agccttattt
     6361 gctggtaaag gtgtttgtcg taactctaag ataacggttt taccgtctgt agtcaattga
     6421 cgagatgttg tgtcttgtga gagaacctgt aaaccgataa tacttgtgta aaaggttgtc
     6481 atctttgcta gatcggtaac atttagagaa accgttccta aagagatggt tgagttgtaa
     6541 gggtatgtca tcctattacc tccaaaaact aattaaatct atcataacca atcagtttca
     6601 aaaagaaaag taggcacaaa taagtggtat aggcactaaa aagtaactca ttta
//
LOCUS       DAUGOH010000060         6214 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUGOH010000060 DAUGOH010000000
VERSION     DAUGOH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6214
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.060"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            148..4254
                     /gene="cas9"
                     /locus_tag="VH957_001582"
     CDS             148..4254
                     /gene="cas9"
                     /locus_tag="VH957_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEQ8559476.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSK
                     SRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPEFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSDILKE
                     YPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWKQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNFGA
                     PAAFIYFDTTIGRNRYKSIKEVLDATLIHQSITGLYETRIDLSQLGGD"
     gene            4254..5123
                     /gene="cas1"
                     /locus_tag="VH957_001583"
     CDS             4254..5123
                     /gene="cas1"
                     /locus_tag="VH957_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8559477.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNDKEMYLTNIISDYTKKVVKA
                     LNNEGKGVPEFRI"
     gene            5120..5461
                     /gene="cas2"
                     /locus_tag="VH957_001584"
     CDS             5120..5461
                     /gene="cas2"
                     /locus_tag="VH957_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8559478.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5451..6113
                     /gene="csn2"
                     /locus_tag="VH957_001585"
     CDS             5451..6113
                     /gene="csn2"
                     /locus_tag="VH957_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEQ8559479.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSEL
                     KFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLVVFVNSGAFLTKEEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
BASE COUNT         2179 a          904 c         1228 g         1903 t
ORIGIN      
        1 aagtattggg tagtattttt tgaagagata ttttgaaaaa gaaaaattaa agcatattaa
       61 actaatttcg gaggtcatta aaactattag tgaaatcatc aaactcatta tggatttaat
      121 ttaaactttt tattttagga ggcaaaaatg gataagaaat actcaatagg cttagatatc
      181 ggcacaaata gcgtcggatg ggcggtgatc actgatgatt ataaggttcc gtctaaaaag
      241 ttcaaggttc tgggaaatac agaccgccac agtatcaaaa aaaatcttat aggggctctt
      301 ttatttgaca gtggagagac agcggaagcg actcgtctca aacggacagc tcgtagaagg
      361 tatacacgtc ggaagaatcg tatttgttat ctacaggaga ttttttcaaa tgagatggcg
      421 aaagtagatg atagtttctt tcatcgactt gaagagtctt ttttggtgga agaagacaag
      481 aagcatgaac gtcatcctat ttttggaaat atagtagatg aagttgctta tcatgagaaa
      541 tatccaacta tctatcatct gcgaaaaaaa ttggcagatt ctactgataa agcggatttg
      601 cgcttaatct atttggcctt agcgcatatg attaagtttc gtggtcattt tttgattgag
      661 ggagatttaa atcctgataa tagtgatgtg gacaaactat ttatccagtt ggtacaaacc
      721 tacaatcaat tatttgaaga aaaccctatt aacgcaagta gagtagatgc taaagcgatt
      781 ctttctgcac gattgagtaa atcaagacga ttagaaaatc tcattgctca gctccccggt
      841 gagaagagaa atggcttgtt tgggaatctc attgctttgt cattgggatt gacccctaat
      901 tttaaatcaa attttgattt ggcagaagat gctaaattac agctttcaaa agatacttac
      961 gatgatgatt tagataattt attggcgcaa attggagatc aatatgctga tttgtttttg
     1021 gcagctaaga atttatcaga tgctatttta ctttcagata tcctaagagt aaatagtgaa
     1081 ataactaagg ctcccctatc agcttcaatg attaaacgct acgatgaaca tcatcaagac
     1141 ttgactcttt taaaagcttt agttcgacaa caacttccag aaaagtataa agaaatcttt
     1201 tttgatcaat caaaaaacgg atatgcaggt tatattgatg gaggagctag ccaagaagaa
     1261 ttttataaat ttatcaaacc aattttagaa aaaatggatg gtactgagga attattggcg
     1321 aaactaaatc gtgaagattt gctgcgcaag caacggacct ttgacaacgg ctctattccc
     1381 catcaaattc acttgggtga gctgcatgct attttgagaa gacaagaaga cttttatcca
     1441 tttttaaaag acaatcgtga gaagattgaa aaaatcttga cttttcgaat tccttattat
     1501 gttggtccat tggcgcgtgg caatagtcgt tttgcatgga tgactcggaa gtctgaagaa
     1561 acaattaccc catggaattt tgaagaagtt gtcgataaag gtgcatcagc tcaatcattt
     1621 attgaacgca tgacaaactt tgataaaaat cttccaaatg aaaaagtact accaaaacat
     1681 agtttgcttt atgagtattt tacggtttat aacgaattga caaaggtcaa atatgttact
     1741 gagggaatgc gaaaaccaga atttctttca ggtgaacaga agaaagccat tgttgattta
     1801 ctcttcaaaa caaatcgaaa agtaaccgtt aagcaattaa aagaagatta tttcaaaaaa
     1861 atagaatgtt ttgatagtgt tgaaatttca ggagttgaag atagatttaa tgcttcatta
     1921 ggcacctacc atgatttgct aaaaattatt aaagataaag attttttgga taatgaagaa
     1981 aatgaagata tcttagagga tattgtttta acattgacct tatttgaaga tagggagatg
     2041 attgaggaaa gacttaaaac atatgctcac ctctttgatg ataaggtgat gaaacagctt
     2101 aaacgtcgcc gttatactgg ttggggacgt ttgtctcgaa aattgattaa tggtattagg
     2161 gataagcaat ctggcaaaac aatattagat tttttgaaat cagatggttt tgccaatcgc
     2221 aattttatgc agctgatcca tgatgatagt ttgacattta aagaagatat tcaaaaagca
     2281 caagtgtctg gacaaggcga tagtttacat gaacatattg caaatttagc tggtagccct
     2341 gccattaaaa aaggtatttt acagactgta aaagttgttg atgaattggt caaagtaatg
     2401 gggcggcata agccagaaaa tatcgttatt gaaatggcac gtgaaaatca gacaactcaa
     2461 aagggccaga aaaattcgcg tgagcgtatg aaacgtattg aagaaggaat aaaagaacta
     2521 ggaagtgata ttctaaagga gtatcctgtt gaaaacactc aattacaaaa tgaaaagctc
     2581 tatctctatt atctccaaaa tggaagagac atgtatgtgg accaagaatt agatattaat
     2641 cgtttaagtg attatgatgt cgatcacatt gttccacaaa gtttcattaa agacgattca
     2701 atagacaata aggtactaac gcgttctgat aaaaatcgtg gtaaatcgga taacgttcca
     2761 agtgaagaag tagtcaaaaa gatgaaaaac tattggaaac aacttctaaa cgccaagtta
     2821 atcactcaac gtaagtttga taatttaacg aaagctgaac gtggaggttt gagtgaactt
     2881 gataaagctg gttttatcaa acgccaattg gttgaaactc gccaaatcac taagcatgtg
     2941 gcacaaattt tggatagtcg catgaatact aaatacgatg aaaatgataa acttattcga
     3001 gaggttaaag tgattacctt aaaatctaaa ttagtttctg acttccgaaa agatttccaa
     3061 ttctataaag tacgtgagat taacaattac catcatgcac atgatgcgta tcttaatgcc
     3121 gtcgttggaa ctgctttgat taagaaatat ccaaaacttg aatcggagtt tgtctatggt
     3181 gattataaag tttatgatgt tcgtaaaatg attgctaagt ctgagcagga aataggcaaa
     3241 gcaaccgcaa aatatttctt ttactctaat atcatgaact tcttcaaaac agaaattaca
     3301 cttgcaaatg gagagattcg caaacgccct ctaatcgaaa ctaatgggga aactggagaa
     3361 attgtctggg ataaagggcg agattttgcc acagtgcgca aagtattgtc catgccccaa
     3421 gtcaatattg tcaagaaaac agaagtacag acaggcggat tctccaagga gtcaatttta
     3481 ccaaaaagaa attcggacaa gcttattgct cgtaaaaaag actgggatcc aaaaaaatat
     3541 ggtggttttg atagtccaac ggtagcttat tcagtcctag tggttgctaa ggtggaaaaa
     3601 gggaaatcga agaagttaaa atccgttaaa gagttactag ggatcacaat tatggaaaga
     3661 agttcctttg aaaaaaatcc gattgacttt ttagaagcta aaggatataa ggaagttaga
     3721 aaagacttaa tcattaaact acctaaatat agtctttttg agttagaaaa cggtcgtaaa
     3781 cggatgctgg ctagtgccgg agaattgcaa aaaggaaatg agctagctct gccaagcaaa
     3841 tatgtgaatt ttttatattt agctagtcat tatgaaaagt tgaagggtag tccagaagat
     3901 aacgaacaaa aacaattgtt tgtggagcag cataagcatt atttagatga gattattgag
     3961 caaatcagtg aattttctaa gcgtgttatt ttagcagatg ccaatttaga taaagttctt
     4021 agtgcatata acaaacatag agacaaacca atacgtgaac aagcagaaaa tattattcat
     4081 ttatttacgt tgacgaattt tggagctccc gctgctttta tatattttga tacaacaatt
     4141 ggacgaaacc gttacaaatc aattaaggaa gtcttagatg caaccctcat ccatcaatcc
     4201 atcaccggtc tttatgaaac acgcattgat ttgagtcagc taggaggtga ctgatggctg
     4261 gttggcgtac tgttgtggta aatacccact cgaaattatc ctataagaat aatcatctga
     4321 tttttaagga tgcctataaa acggagctga tccatttatc agaaattgat attttgttat
     4381 tagaaacgac cgatattgtc ttgtccacta tgctggtaaa acggctagtg gatgagaatg
     4441 tccttgtcat attctgtgat gataaacgat taccaacagc tatgctgatg cctttttatg
     4501 gtcgtcatga ttcgagtcta cagcttggga aacaaatgtc ctggtcagaa acagtcaaat
     4561 cgcaggtttg gacgacgatt attgctcaaa agattttgaa tcaatcttgc tatttaggag
     4621 catgctccta ttttgaaaaa tcccaatcta ttatggattt atatcatggt ttggaaaatt
     4681 ttgatccgag taatcgagaa gggcatgcag cgagaattta ttttaataca ctttttggga
     4741 acgatttctc aagagatttg gagcatccaa tcaatgcagg tctggattat ggttatactt
     4801 tattattgag tatgtttgcg cgtgaagtgg ttgtgtctgg atgtatgact cagtttgggc
     4861 ttaaacacgc taatcagttt aatcagttca attttgctag cgatattatg gaaccattta
     4921 ggcctttagt ggataagatt gtttatgaaa atcgaaatca gccttttccc aaaataaaga
     4981 gagagttatt tactttgttt tcagatacat tttcatataa tgataaagag atgtatctca
     5041 cgaatattat tagcgattat actaaaaaag ttgtcaaagc tctgaataat gaagggaaag
     5101 gagttcctga atttaggata tgagttatag atatatgaga atgatactta tgtttgatat
     5161 gccgacggac accgctgagg aacgaaaagc ctatcgaaaa tttcggaaat ttttacttag
     5221 tgaagggttt atcatgcatc aattttctat ttatagtaag ttgctgttga ataatacagc
     5281 taacaatgcc atgattggtc ggctgaggga gcataatcct aataaaggaa atattacatt
     5341 actaacggtc acggaaaaac agtttgcacg aatgatttat ttacatggtg aaagaaataa
     5401 ttgtattgca aactccgatg aaagacttgt atttcttggg gaggcttttg atgaatctta
     5461 atttttcctt actagatgaa ccaattccat taagaggcgg tacaattctt gtgctcgaag
     5521 atgtctgtgt attttcaaaa atagtgcaat attgttacaa atatgaggaa gattctgaac
     5581 ttaaattttt tgatcacaag atgaaaacca tcaaagaatc agaaatcatg cttgtaacag
     5641 atattttagg atttgatgtt aactcctcaa ccattttaaa attgattcat gcagatttag
     5701 aatctcaatt taatgagaaa cccgaagtga aatcgatgat tgacaaattg gttgctacga
     5761 ttacagaact gattgtcttt gaatgcttag aaaatgaatt agatttagag tatgatgaaa
     5821 tcacaatcct ggaattgatt aagtccttag gagtaaaagt agaaacacaa agtgatacta
     5881 tttttgaaaa atgtctagaa atacttcaaa ttttcaaata tctcaccaag aaaaagttag
     5941 tcgtctttgt caatagcgga gcttttctaa caaaagagga agtggctagt ttacaagagt
     6001 atatatcatt gacaaattta acagttctct ttttagaacc acgtgaacta tatgattttc
     6061 cgcagtatat tttagatgaa gactatttct taataactaa aaatatggta taatattctt
     6121 aataaatgca gtaatacagg ggcttttcga gattgaagtc tagctgagac aaatagtgcg
     6181 attacgaaat tttttagaca aaaatagtct acga
//
LOCUS       DAUGOH010000061         6021 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUGOH010000061 DAUGOH010000000
VERSION     DAUGOH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6021
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.061"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(311..1183)
                     /locus_tag="VH957_001586"
     CDS             complement(311..1183)
                     /locus_tag="VH957_001586"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEQ8559480.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEAESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1407..2717
                     /locus_tag="VH957_001587"
     CDS             1407..2717
                     /locus_tag="VH957_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEQ8559481.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTIFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            2795..3945
                     /locus_tag="VH957_001588"
                     /pseudo
     CDS             2795..3945
                     /locus_tag="VH957_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4074..4226
                     /locus_tag="VH957_001589"
                     /pseudo
     CDS             4074..4226
                     /locus_tag="VH957_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4273..4803)
                     /locus_tag="VH957_001590"
     CDS             complement(4273..4803)
                     /locus_tag="VH957_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEQ8559482.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(4796..>6021)
                     /locus_tag="VH957_001591"
     CDS             complement(4796..>6021)
                     /locus_tag="VH957_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HEQ8559483.1"
                     /translation="GLLLNILLDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQETFTS
                     LEGRKKVSLYWVCLPMATRTALSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSI
                     TTYRYKMNQEDLAKQFGRWYKQIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKEC
                     WITKQFKDVWTASPLYDWSVEDIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVASPFQ
                     DYAVDSLNLYRIIDQETWVKLLGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQ
                     FLLSTLPVRLRNNYVRKFNKSIDFWHKTGGGLAEETINELIEKGYRIARNGISNYTTF
                     KHSRVIFLDQIPDDTDDIVTTKDVPSWKRMCFCILKNDHICRTMGFGLTREQQKIVAF
                     LKEKYKTSLKELESE"
BASE COUNT         1857 a         1299 c          971 g         1894 t
ORIGIN      
        1 cctttcaata attatttgtc caactttttg gggtcagtac actcctagtt aacgactttg
       61 attgatttta ttatgatgaa tcgtgatttc tgaaaacaaa cttttcttca tggatttggc
      121 gtggaacttt tacaataaaa acactaacct ctccctatcg ttttttcagg tgaatgcttg
      181 gaattggtat aataagcgga cacgaatcag gtgaaaacag ggaaagtatt tgaaaaggcg
      241 tttaaactat ctgacataaa actcgttcta gaggaaagac atcctttaaa aagttagttt
      301 attttgcaac ttagacatca aggtaggtta aacccttcat ggaaaaatcg agactcttag
      361 cactatgggt taaactacca ctggagacgt aatcaatcgc taaaccacga aaacggctaa
      421 tagtggtcat atcaatattt ccagaacatt caatccgaga acgtcctgca attagagtaa
      481 tggcctgttc aatctgttcc aatgacatat tatccaacat gataatatca acacccgccg
      541 ccgcagcttc ttcggcagca gcaaggcttt ccgcttccac ctcgaccatt ttcacaaaag
      601 gggcataggc acgcgcttga gcaatcgcct tttgaacact acctactgcc gcaatgtgat
      661 tgtcttttag catgatagca tctgataaat taaagcgatg attatagcca ccgccaactc
      721 tcacggcata tttctcaaaa agacgtaaat taggagtggt ttttcgagta tcaaatacct
      781 taatgcgatc atcgcctaag gcttctacat aagcagctgt catcgaagca atccctgata
      841 aatgttgtaa aaaattcaag gcaacgcgtt cacatgttaa gaggcttctc accgagccta
      901 tgatttctaa aaccaaatcg ccactagtca aacgatcccc atccttaaat tgatgaggat
      961 tctggaaggt cacctcggca tcaaataggg taaaaaccct ttgaaaaacg gttagccccg
     1021 ctaaaacacc agcttccttg gcaaaaagcg acaccttggc ttggccatga tgatcaaaaa
     1081 tggcattggt actgtaatct tcggaatgaa catcttctcg caaggctgct ttcaatgtat
     1141 catctatttg aaaaggggtt aaatcagttg aaatgattga catcactaag tcctctattt
     1201 ttaatatcac ttgtaagcac tagaggcaat tgctattaac ttccgtagga aatcacaaac
     1261 ctgaatacct cattttaaat cccaacaagt gtcaagacaa ttgtaatttt tttgtgtata
     1321 atagtcaagt accaatagga aacaggtggt cttttgagcg ccaaaattgc caacctattt
     1381 tcatattcta actaaaggac aattcaatga ttcatttaat aataattagc gccattgctc
     1441 tagccattgg aattggttac cgcaccaaaa tcaatattgg cctgctggct attgcttttt
     1501 cttacctcat cgcaaccact ctcatgggat taagccccaa agaacttctt catttttggc
     1561 caacctcact cttttttacc atttttagcg tctctctctt ttataacgtt gcaacaacta
     1621 acggcactct tgatgttttg gctcaacaca ttctctaccg cacacgcacc caccctaacg
     1681 ccctctacat gattttatac ctgatagcaa cccttttgtc tgctttaggt gctggatttt
     1741 tcactactat ggccgtttgc tgtcctctag cgattaccct ctgtcaaaaa gcggacaaac
     1801 accctttgat tggagctcaa gccgtcaatt ggggagcttc aggaggggct aatttgataa
     1861 ccagtggctc aggcattgtc tttcaaggcc tgtttaagca aatgggatgg gaagagcaag
     1921 ctttttcact tggcaatcat atctttatcg tcagcattat ctacccactc atcgtcttgc
     1981 ttttattatc ttgttacatc cgctacagta aaggaagaac aaactcatcc ttgactattg
     2041 accaaccacc agtcctcagc aaggtccaaa gacaaaccac cttgctcatg atcagcagca
     2101 tggttttggt ttggcttttt cccttgttgc atctcatttt cccaaacatc gcatggatag
     2161 ctacttatcg acaaacattt gatattggct ttgtctcaat actcatggtc tgcctcgcct
     2221 taaggctcaa attagggaag caagaagcca ttttggctaa ggttccctgg gctataatta
     2281 tcatgctctg cggcatgagc ttactaatgt ctctagcggt caagtcaggt ttagttacac
     2341 tgatagggca cctcataaca acaaccattc ctcatttctg gttacctctg ttcttttgtg
     2401 tgatagccgg agtaatgtca ctctttagtt ccaccctatc cgttgtagcc ccaactatct
     2461 ttcccatcat tgctaccatc agtgctcaaa gtcctcacat tgatattcgc ttactcacaa
     2521 cagccactat tattggcgct ctatctacta atatctctcc tttttcatca gctggttctc
     2581 tcattcaact ctcccttccc catatagagg aacgcagtct tgctttcaaa aaacaaattc
     2641 ttctgggtgt gcccatcagc ttaagtttgg cactcttgac catctggatt ctcatgctgc
     2701 tagcttcctt aagttagatt tattgtctaa cttaaggctg gacttggtat actaaagtag
     2761 acacaaaatt aagtgaaaac gaggaatagt cattatgcca agaaaaacct ttgataaagc
     2821 cttcaaactc tctgctgtaa aactcatcct tgaggaagag cagcctgtaa aaatggttag
     2881 ttcaacttta gaaattcatc ccaatagtct ttatcaatgg attcaagaat atgaaaaata
     2941 tggagaaagt gcgttcccag gacatgggag cgcacttcgt catgctcaat ttgagataaa
     3001 aaaacttgaa aaagagcgca aactgctaca ggaggaatta gctcttctaa aaaagttcca
     3061 ggtcttcttg aagccaaacc ggaaataaaa tttcagtttc tgaagaaaaa tagtgttagc
     3121 ttgaatagtc atcacgcctg tcaaactctt caagtctctc gttcaggttt ctatgcttat
     3181 ttaaaacgtc gtccctcttc aaggcatgtt gagaatgaag ctttaaagga aatgattaaa
     3241 gccattttct atgaacataa agagcgttac ggaagtgtac gaattaccca agaactttgt
     3301 agacgtggca tccatgtcaa ttataaatgt gttggtagac tccttcatca gctaggtctc
     3361 tatgctaaag gaagtcgata tcaatataaa tactataacc gtcgacgttc ttcattaact
     3421 cgtcccaatc ttgttaatca atgtttccaa gcgactggta agaataaatt atggctagga
     3481 gacttaacct acattcctac acaagaagga atactttatg tgtctgtctt gatagacgtt
     3541 tatagtagaa agattgttgg ttgggcaatg ggccgacgta tgcaagacaa gttggtaaca
     3601 gaagctttca aacaagctta taatagagaa aagcctaaag aaggggtaat cgtccataca
     3661 gatcagggtt ctcaatatac cggagcatga tttcaggacc tacttagaca gaaaaaatgt
     3721 aagtccagta tgaatcgaaa aggtaatcca tacgataatg cactcatgga atccttttat
     3781 aaaacattaa aaagagagct tgtcaatgat gctcatttcg caactattaa gcaagctcag
     3841 cttgagattt ttaaatatag tgagacttac tataacccca aacgtctgca ttcagcttta
     3901 gggtatctct cacctgttga atttgaaaaa atagttactc attagcttaa ctttatgtct
     3961 atttttcttg acaagtccag ggtatgaagt ccccttatac acatactttc aaaacagctc
     4021 tcaatcctct gtccgctaca aaaatacgtc accgctgccc tccagctgct tcattcaacg
     4081 acaaacttga agccacaaac agactcatca agggcattaa gtacaatgcc tttagatttc
     4141 agaactttga caactttaaa accaaaatcc tcatcgcttt gaacatccaa aaagagagaa
     4201 ccaatctgat tctctctcgt tgttaatgat aagtcaccca ctacagttga caatgagtct
     4261 cttacttcct gtttactcat ttaatagctc ttctggttcc caagattgat taaactcatg
     4321 gtccttaaaa agagaagcca atcctgttat ttgtttcagt cttaaaattt catctttatc
     4381 cattcctaaa tgttttgcaa tccagttatc acttcgccca cactcatgaa gatcctttac
     4441 aatctgactc atcaaatcaa catcatgact tcctctagct ctattatgtc gaatggtaga
     4501 agccattcga tagtctaatg acttatcaat aacagaaaca ggtaatctcc cactttccct
     4561 ttcataaata tctgaataat ctagcattat acgatatcta tgaaaaccat caacaatact
     4621 ataccgatcc tcttccttat cgtaatagca aacaatcggc atagtataac catcagattt
     4681 tatactatca tacaataatt tcatttcagg cggagcaact gaattcggat tataatcatt
     4741 tggagaaatc ttttcaattg gaattgattt aatctcatag actggactaa taaaattact
     4801 cactttctaa ctcctttaaa ctcgtcttat atttctcttt taaaaaggct actatttttt
     4861 gttgctctct tgtcaaacca aaccccatag ttcgacaaat atgatcattt tttaaaatac
     4921 agaaacacat tcgtttccag cttggtacat cctttgttgt tacaatatcg tctgtatcat
     4981 caggaatttg atctaaaaaa ataacccttg aatgtttaaa agtggtataa tttgaaatac
     5041 catttctagc aatacgatat cctttttcaa ttagttcatt aattgtttcc tccgcaagtc
     5101 ctccgcctgt tttatgccaa aagtctattg atttattaaa ttttctaaca taattatttc
     5161 ttaacctcac tggtagcgtt gataaaagaa actgagtata cgacttccac gaatgaccct
     5221 ttggtaaagc aattgattta tatcccattg ctttagtacg tccataaata ttcgaaaagt
     5281 taactccttg aacacgtccc aaaagcttta cccaagtttc ttgatctatt attctataaa
     5341 gatttaggct atcaacagca tagtcttgaa aaggagatgc aactctcatt tgtgatggtt
     5401 ttaaacccgc tttatagaat agatcataaa gttcgttata agaataagaa aacttatagt
     5461 aagcatgcca tatgtcttcc actgaccaat catataaggg agatgctgtc cagacatctt
     5521 tgaattgttt ggtaatccag cattcctttt gataaccata ctttttattg ataaaaccac
     5581 tatatctgtg taaggattct gaagcacggt ttcctaatat acaaactgtt ttttgatttc
     5641 cgtgaatttg tttataccac ctaccaaatt gtttcgctaa atcctcctga ttcattttat
     5701 aacgataagt agtaattgaa ttattttcca aattaataac ataatcttga gatggcattg
     5761 gtcttaccca gatatcttct gttttgtcat cccacggata ccaaaacatt tcataactac
     5821 taagtgcagt tctagtagcc atcggtaagc acacccaata caaagaaact ttttttctac
     5881 cttctaaaga agtgaatgtt tcttgaacat attttgttgt taaactgtac tgtgcttcaa
     5941 aatcttgatg aaacacacct atttctctat ccggataata tttatctcta aaatccagta
     6001 aaatattaag aagtaaccca c
//
LOCUS       DAUGOH010000062         5945 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUGOH010000062 DAUGOH010000000
VERSION     DAUGOH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5945
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.062"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            49..762
                     /locus_tag="VH957_001592"
     CDS             49..762
                     /locus_tag="VH957_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8559484.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKTIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            759..1670
                     /gene="pfkB"
                     /locus_tag="VH957_001593"
     CDS             759..1670
                     /gene="pfkB"
                     /locus_tag="VH957_001593"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEQ8559485.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISQEQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNAIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            1667..3613
                     /locus_tag="VH957_001594"
     CDS             1667..3613
                     /locus_tag="VH957_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8559486.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVAIGAIVSGILFGALRKKA"
     gene            3705..4304
                     /locus_tag="VH957_001595"
     CDS             3705..4304
                     /locus_tag="VH957_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8559487.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            4455..5162
                     /locus_tag="VH957_001596"
     CDS             4455..5162
                     /locus_tag="VH957_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8559488.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNAYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(5219..5530)
                     /locus_tag="VH957_001597"
                     /pseudo
     CDS             complement(5219..5530)
                     /locus_tag="VH957_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(5734..>5945)
                     /locus_tag="VH957_001598"
     CDS             complement(5734..>5945)
                     /locus_tag="VH957_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8559489.1"
                     /translation="MESKEIHLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDV
                     LKKYKDNKTINMKDFSHFDIYLWTK"
BASE COUNT         1782 a          999 c         1248 g         1916 t
ORIGIN      
        1 tcagttaggg gtggttctat cttaaaatca aaacgaaaac aattaatcat ggcaaagatc
       61 actgaagaaa actatgtttc tttagaggat ttaatgcaat tactcaactc ctctgagtct
      121 actatccgta gagatctagg agagttggag caagaaggac ggctacatcg tgttcatgga
      181 ggtgctgaac tttttcactc tttacaagag gaactttcta accaagaaaa gtctgtcaaa
      241 aacagtcata ttaaaaaaac tattgcgcaa agagcctctc agtttatcta tgacaacgat
      301 gtgatcttta ttgatgctgg gacaacgact gaatttttat tacctttttt acaagctaaa
      361 aatttaactg tagttactaa ttctattcat catgctgcta gattagttga actctctatt
      421 gagacgatta ttgtaggggg ttatgtcaaa caaacgaccg atgccagtat tggtaatgta
      481 gctttggaac agattaggca gatgaatttt gacaaggcat ttcttggaat gaatggtgtt
      541 gatgattctt acctgacgac tcctgatatg gaagaagcag ttattaaaaa agcggttctg
      601 tcaaatgcaa aattagctta cattttagta gatggcacta aaattggtca ggtatcgttt
      661 gtaaaagtag ctcctattaa tgatgtgact attattacat taggaggatc agcaagtatt
      721 cttaaacaaa taaaggaaaa ggcaaaggtg attgaattat gatttatacc gtgaccttaa
      781 acccttctat tgactttatt gtcagaattg accaaataaa tcttgggtca gtgaatcgca
      841 tggcgagtga tgataagttt gctggaggta aaggcattaa tgtgagtcgc atcttgcaac
      901 gtttagacat tgctagcacg gcgacagggt tcttgggtgg ttttacagga cgttttatcg
      961 aagaaagttt gagtgcagaa ggcgttaaaa ctgattttgt aaaaggtgat caagatactc
     1021 gaatcaatgt taaaatcaag tcacaagaag agaccgaatt aaatggtcaa ggacctatca
     1081 ttagtcagga acaactagag gagttgaaaa ctaagctttc ccagctaaca gcagaggata
     1141 cagttgtctt tgcaggttca gcgccagcta atcttggcaa tgctgtttat aaggaattac
     1201 ttcctttagt taggcaaagc ggtgctcagg tggtttgtga ttttgaagga cagactttaa
     1261 tagatgcgct tacatataat cctctgttgg ttaaacctaa taatcatgaa ctagaagcta
     1321 tttttggtac gattctgact agtcttgatg atgttgaaac ctatgcccgt cgtcttttag
     1381 agatgggtgc tcaaaatgcc atcatttcaa tggctggtga tggtgctttg ctggttacta
     1441 aagaagcgac ttattttgct aaaccgatta agggagaagt taaaaattct gtcggtgctg
     1501 gtgattcgat ggttgctggc tttacaggcg aatttatgaa gagtcaaaat ccaatagaag
     1561 ccttaaaatg gggcgtggct tgtggtacag cgacggcttt ctctgatgac ttggcgacaa
     1621 ttgcatttat taaggaaaca tatcataaag ttgaggtaga aaaacgatga aaattcaaga
     1681 tttattgaga aaagatatta tgattctcga tttacaggct atttctaaag aagttgccat
     1741 tgacgagatg attactaaat tagttgaaaa agatattgta catgattttg atgtctttaa
     1801 aaagagtatc atgacacgtg aagaacaaac atcaacaggg cttggtgatg ggattgccat
     1861 gcctcattct aaaaatattg tagtagataa accagcggtc ttgtttgcga aatcaaataa
     1921 aggcgtggat tataaggctt tagatggtca accaacggat ctcttcttta tgattgctgc
     1981 gcctcaagga gcaaatgata ctcacttggc tgcgctagca gaattatcac aatacctttt
     2041 gaaagacggc tttgctgata aacttcgtgc tgcagcgaca ccagaagcag tcattgctgt
     2101 ttttgatgaa gcgtcaacag ctaaagaaga agtggttgct ccaacaagtg gtcaagactt
     2161 tatcgttgct gttacagctt gtccgacagg aattgctcac acttatatgg cagaagaggc
     2221 tttgaaaaaa caagctgcag aaatgggagt agctattaaa gttgaaacaa acggtgcttc
     2281 tggtgtggct aatcgtttaa ccgctgaaga tattcagaga gctaaaggag ttattgttgc
     2341 agctgataaa gcggttgaaa tggaccgttt tgatggtaaa caattcattg ctcgccctgt
     2401 tgcagatggt atcaagaaaa gtcaggaatt gatttctttg attttaaaca atgaaggaaa
     2461 cacttatcat gctaaaaatg gaaaatctga aacagcagta tcaactgaga aaacaagttt
     2521 aggcggtgct ttctataaac acttgatggg cggtgtctca caaatgttgc catttgttat
     2581 tggtggcggg attatgattg ctctagcatt tttattggat aacatgcttg gtgtgccaaa
     2641 tgatcagctt ggaagtcttg gatcctatca tgaaatagca gctattttta tgaacattgg
     2701 tggagcagcc ttttccttca tgttaccagt actagcaggt tatatcgctt attctattgc
     2761 tgaaaaaccg ggcttagtag ctggttttgt ggcaggtgcc attgcctcaa atggtcttgc
     2821 ttttggtaag gtaccatttg cagcaggagg agaagtgagc ttgggcttaa cgggcgtgcc
     2881 atcaggtttc cttggggcgc ttgtgggtgg tttccttgcc ggtggtgtta ttcttgccct
     2941 tcgtaaattg ttggcaggcc taccacgttc tctagaaggg gttaaatcta tcctccttta
     3001 cccattactt ggcgtccttg tcactggttt cttgatgctt tttgtcaata ttccaatggc
     3061 agctattaac acagccctta atgatttctt acaaggtctt tcaggaagct ctgctgtcct
     3121 tatgggactt cttgttggtg gaatgatggc tgttgacatg ggtggtcctg ttaataaggc
     3181 agcttatgtt tttggtacag gaactttagc agctactgtc gcaaatggcg gttcagtcgt
     3241 tatggctgct gttatggcag gtggtatggt acctcctcta gctgtttttg tagccactct
     3301 cttgtttaaa gataaattta ccaaagaaga acgtgaatca ggtttgacca acattgtcat
     3361 gggactttct ttcatcactg aaggagcaat cccatttggc gcagctgacc cagcgcgtgc
     3421 aattcctagc tttattgctg gttctgcctt gacaggagct cttgttggtt tggctggtat
     3481 taaattaatg gcgccacatg gtggtatctt cgtcatcgcc ttaacaagta atccaatctt
     3541 ataccttgtc tttgtagcga ttggtgctat tgtatccgga atcctcttcg gtgcccttcg
     3601 taaaaaagct taacgttaaa agactttttc cttactaaaa ctagaatctg ctaaggttct
     3661 agttttttga tatactagag ttaaaggata agaaatgagg acctttgaag gtgaaaaaaa
     3721 ggagaagaag ggctaaatca tcagtaaatc gacttgtctt agggttagta ttacttaatc
     3781 tgattgttag tatgtggaca ttaaaattgg gaaaccagcg attagctccg tatgcggatc
     3841 acgaaactct gacatttgtc aggaagatta gtcatgctgc tcaatcagtc gctcaaaaga
     3901 aacagttata cagttcggtg atgatggctc aggccatttt agaatccaat aatggtaagt
     3961 cacaactaag tcaaaaacct tattataatt ttttcgggat taaggggagc tataaagaac
     4021 ggtcagtcat ttttccaact ttagaagacg atggacaagg gaatctttat caaattgatg
     4081 ctgcttttcg ttcctatggg agcctgacag cttgtttttt agattacgca agagttttga
     4141 atgatccact ttatgacaaa acccacaaaa agttttggtc tcattatcaa gatgctactg
     4201 caaccttaac aggcacttac gccactgata caacttacca taccaaatta aatgaattga
     4261 ttgaatggta tcaactcact aattttgatg gtctaatgaa atagttatcc acaattttaa
     4321 aaaaatcaga agaaatatgt cgatttcaag acaaaagtta tcaatctcat taaattatct
     4381 gtggaaaagt taatttaaac gttcgtgtgc tataatagaa acatagaaaa tgtataaaaa
     4441 aggatatgtg aataatgaca aaaaagaaag gtaagcttgt acttatcagt ctttttgttc
     4501 tagcagcttg tttaggagct tatagtgcaa tgagacaatc tcataaaact tcaaacgtgt
     4561 cagctgagac tatcgccagt tcttcaaccc gacattttat tgatgaaatt ggtccaactg
     4621 ctagtactat tggtcaagaa cgtgatcttt atgcgtctgt tatgatagca caagcgattt
     4681 tagaatcaag taatggtaaa tcaagtctaa gtcaagcacc ttattataat tttttcggta
     4741 ttaagggtgc ctataacggt tcttctgtga cgatgtcaac ttgggaagat gatggtaatg
     4801 gcaatgccta tacgattgat caagccttta gagcttatcc aagtattgca gactccctta
     4861 atgactatgc agacttgcta agttctagca cttatatagg tgctagaaaa tcaaacacgc
     4921 tatcgtatca agatgctaca gcagctctaa ctggcttata cgctacagac accagttata
     4981 acttaaaact aaataatatt attgcaacct atggtttgac ggcttatgat gttgctaata
     5041 gctcagctca agaaactggt ctagcaactt cgggttatgt ttggaatgag tatcgtcgta
     5101 attacactga tgcggagacc ctagcagttg atgaggcttg ggctaaacgc atgacttatt
     5161 aatgtaacac taacaacaat ctgcttgcac tgaccccaaa aaagctggat actctatttt
     5221 aagtaaagga tttagttctg tattgtacag aactaaatcc ttttagtttt actttgatat
     5281 gtttatcgtt gtaataatca atgtcatttg taatcgctta ttctaagtct tctagtgatt
     5341 tatagttatt ctcataacca tagaacattt ctgactttaa gatgccaaag aaagattcca
     5401 tcatgctatt gtcaggactg tttcttttac gtgacataga cggacgaatt cctttagagt
     5461 ttaggaaatg atgataatag ttgtgttgat attgccaacc ttgatcactc tatcatatag
     5521 ttccatcata gcatttattt ggagatgtct ttttccatta ttggtttaat gtgatttaag
     5581 caaggttatt agctaaactt aatgccagac aaaaacaccc caattattag attttttgtc
     5641 taacttttgg ggcgcaattc aatctgagca gttttagatt tggtatcaat gttattatag
     5701 gtcaattgat catatttatc caaagctttt agcttattta gtccaaagat aaatatcaaa
     5761 atggctgaaa tctttcatgt ttatagtctt attgtcttta tattttttta agacatcaga
     5821 tctggtgcta ttgggttttg cgtcatataa attgattttt tcatgtttcc tatttttact
     5881 gtgaatttct aaactccccc ttatataagg agacttagtc aaatgaattt cttttgattc
     5941 catca
//
LOCUS       DAUGOH010000063         5797 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUGOH010000063 DAUGOH010000000
VERSION     DAUGOH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5797
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.063"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            118..1407
                     /locus_tag="VH957_001599"
     CDS             118..1407
                     /locus_tag="VH957_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8559490.1"
                     /translation="MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTV
                     GFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQ
                     TSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
                     LQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLA
                     IQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLT
                     YRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHHFQFVLISLDTPEPIAM
                     SNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKET
                     YFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            1457..2482
                     /locus_tag="VH957_001600"
     CDS             1457..2482
                     /locus_tag="VH957_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8559491.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIAILGTVAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2496..3038
                     /gene="pgsA"
                     /locus_tag="VH957_001601"
     CDS             2496..3038
                     /gene="pgsA"
                     /locus_tag="VH957_001601"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEQ8559492.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            3040..3879
                     /locus_tag="VH957_001602"
     CDS             3040..3879
                     /locus_tag="VH957_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8559493.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3855..4697
                     /locus_tag="VH957_001603"
     CDS             3855..4697
                     /locus_tag="VH957_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8559494.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELKEV
                     LKHG"
     gene            4690..5490
                     /locus_tag="VH957_001604"
     CDS             4690..5490
                     /locus_tag="VH957_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8559495.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         1903 a          912 c         1061 g         1921 t
ORIGIN      
        1 cttcttattc tattaaaaat tggattaaag gggttaatga agttaataaa gcagatatca
       61 ttaaagtagc taatctttta aagcttcaaa ctgtctattt tttagaagga atataaaatg
      121 acaaaattag taaagataaa ctatcctaat attgacgaag acctttacta tgtaaaatta
      181 gaaaatggtt taactgttta ttttataaaa aaaatagggt ttttagaaaa aacagctatg
      241 ttgacagtag gtttcggttc tcttgacaat aagttgacag tcgatgacga atcacgagat
      301 gctccagcag gtattgcaca ctttttagaa cataaactct ttgaagatga atcaggtgga
      361 gatatttcat taaagtttac acagctagga gcagagacaa atgcctttac aactttcaac
      421 caaacgagtt tcttcttttc aacagctagt aaatttcagg aaaatttgga actccttcaa
      481 tattttgttc tttctgctaa tataacagat gaatctgtta gtagagaaaa aaaaataatc
      541 gggcaagaaa ttgatatgta tcaagatgat gctgactacc gtgcatatag tggaatcctt
      601 cagaacttat ttccaaaaac aagtttagct aatgatattg ctggctcaaa agcatccatt
      661 caaaagatca cgaaaatatt attggaaacg catcatactt atttttacca acctactaat
      721 atgagtctat tcattgtcgg tgatattgat attgacgaaa cttttttagc tattcaaagg
      781 tttcaaacca cattatccta tccagataga aaaagggtaa ctgttgatcc tttacactac
      841 tatcctgtca ttaaatcatc ttctgttgac atggatgtta ctactgccaa gctggttgtt
      901 ggttttcgag ggtatctgac cttaactcag cattcactat taacgtatcg tattgccttg
      961 aagctatttt tatcaatgct tataggttgg acttctaaaa tctatcatac gctatatgaa
     1021 gatggtaaaa tagacgattc atttgatgtg gatgttgaaa ttcatcatca ttttcaattt
     1081 gtattaatat cacttgatac accagagcct atcgcaatgt ctaactatat ccgtcaaaaa
     1141 ttagccacta taaagatatc aaaagagttt acaaatgagc acttaaatct attaaaaaaa
     1201 gaaatgtatg gtgactttat tcagagttta gactctatag aacatttaac ccatcagttc
     1261 agtctatacc tgtctgattc tgataaagaa acatattttg atattccaaa aattatagaa
     1321 agactcactc taaaagatgt tgttacaatt ggaaaagcat tttttgaaaa agctgatgct
     1381 tcagacttca cagtcttccc aaaatagatg aaaatctgtt ataatagggt tactatatta
     1441 tttttgaggt acctgtatga gtgaaaaaag tcttggtgaa gtgttaagag aatcgcgtgt
     1501 tggaaaaaat atcacactag atgatataga attgaagaca gggatttctt cccattactt
     1561 gctggcaatg gaattggatc agtttaaaat tattccggaa gaaaaatttg atcaattttt
     1621 aaaagaatat gctgacattg ttgagttaga tttcaatact ttaaaaagac gataccgtta
     1681 tcaagttaat tccaaaaaag acagtgatat aaaatctgta actgagattg ttgaagagaa
     1741 gttaagtaag aaacgattac aagagaagtt gttatcacat cagagcatgg ggtatggtca
     1801 accgttagaa gtttctaaaa acaaagaaac cttagttatc cctgtaaaga ctgttggttt
     1861 agatagcaaa tcgccactaa aaacgatatc gcctgttagc caatttaaat cagataacag
     1921 gttaattcct aaaaaaaatg tgtcacgtat gaggcgaaat agcactgaca gtcgttctaa
     1981 aacgtcacta tttcccatag ctatattagg aacggttgct tttgcaatta tcagtgttat
     2041 cattttaggt gtttggcaac aattcgaaaa gagtcaaaga gctaaagaag ctgaagttgc
     2101 tttgcttaaa gcctctgagc agtctactaa cggtttaaaa aataattcaa atgatcgcaa
     2161 aactcaagtc acaactgagg ggtcgggtaa ttatttaata gcgactgtta ctaaatctaa
     2221 agagaccgtt gatatcagtg tgtctttaac tgaggcacaa agtagttgga tttctctaac
     2281 aaattcagaa attggtgaag gtggtataac attgactcaa gactcgccaa cttatacagc
     2341 gactttacct gcagaaataa cagaatcatt gttgacactt ggtgtgacaa aaggtgtatc
     2401 tgtaacaatt gatggacaac ctgttgatct atcaccttta acaagtactg acttaagtta
     2461 tatcacgttt aagatccaat aattaaggta gactaatgat aaaaaaagaa aatattccta
     2521 atctattaac tcttgttcga atcgcaatga ttcctttctt tctttttatt acttcctcat
     2581 ctaataaggt ggggtggcat atttttgcag ctgtgatttt tgcaattgcc agttttaccg
     2641 attatctaga tgggtatctt gcgcgtaagt ggcatgtagc cagtaatttt ggaaagtttg
     2701 ccgatcctct agcagataag atgcttgtca tgagtgcctt tatcatgtta gttggacttg
     2761 gcttagttcc tgcgtgggtg tcagctgtta ttatttgccg agaattggca gtaactggtc
     2821 ttcgattact acttgttgaa accggaggaa aggtccttgc agctgctatg ccgggaaaaa
     2881 tcaaaacagc gacacaaatg ttgtctatta ttttattact ttgccattgg atattcctag
     2941 gaaacgtctt actctatatt gctctttttt tcactattta ttctggatat gattatttta
     3001 aaggagcaag ctttcttttt aaggatacgt ttaaataaca tgtcagctat tattgaactt
     3061 aaaaaagtta catttaatta ccataaagac caagaaaaac caacattaga tggcgtatcg
     3121 tttcatgtga aacaaggtga gtggctgtct atcattggcc ataacggatc tggtaaatca
     3181 acgactattc gattaattga tggattattg gaaccagaat cagggtctat tattgttgat
     3241 ggagatctac taaccataac taatgtttgg gaaattcgtc ataaaattgg tatggtcttt
     3301 caaaaccctg ataatcagtt tgttggagca actgttgaag atgatgttgc ttttgggctt
     3361 gaaaataaag gtattgcaca tgaagatata aaagagaggg ttaatcatgc tttagagtta
     3421 gtcggcatgc agaactttaa agaaaaagaa ccagcccgtt tatctggtgg ccaaaaacag
     3481 cgcgtagcta ttgcaggtgc agttgctatg aagcctaaaa ttattatttt agatgaagct
     3541 actagtatgc ttgaccctaa aggacgatta gagttaatca aaactataaa aaacatccgt
     3601 gacgactacc agctgactgt tatttccatt actcatgact tagatgaagt tgctcttagt
     3661 gatagagttt tagtgatgaa agatggtcaa gtggaatcaa catcaacacc agaacaatta
     3721 tttgcaagag gggatgaact actccaatta ggtcttgata tcccttttac aacatctgtt
     3781 gtacagatgc ttcaagaaga aggttatcct gttgactatg gatatctcac agaaaaggaa
     3841 ttagaaaatc agttatgtca attaatctcc aaaatgtaag ttatacttat caagcaggga
     3901 ctccttttga agggcgtgcc ctttttaaca ttaatttaga tattttagat ggttcttata
     3961 cggcttttat cggacatact ggatccggga aatcgaccat tatgcaattg ctaaatggtt
     4021 tacacgttcc gacaacggga attgtcagcg tagataaaca agatataacg aatcactcta
     4081 aaaataaaga gatcaaatct attcgaaaac atgtaggatt agtttttcaa tttccagaaa
     4141 gtcaactatt tgaagagaca gttttgaaag atgttgcttt tggccctcaa aattttgggg
     4201 tctctccgga ggaagcagaa gctttagcgc gtgaaaaact agctcttgtt gggatttcag
     4261 aaaatctttt tgaaaagaat ccatttgaac tctcaggggg tcaaatgcgt cgtgttgcta
     4321 ttgcgggtat ccttgctatg cagccaaagg ttttagtttt agatgaaccg actgctggtc
     4381 ttgatcctaa agggcgtaaa gaattaatga ctatttttaa aaagttacac caatctggca
     4441 tgactattgt tttagtaacc catctgatgg atgatgtggc caattacgca gattttgtat
     4501 atgttcttga caaaggtaaa attattttat caggaaaacc caaaacaatt tttcaacaag
     4561 tcagtttgct tgagaaaaaa cagttaggag ttcctaaggt gactaaactt gctcaaaggc
     4621 ttgttgatag aggaatacct atctcttctt tgcctattac cttagaggag ctaaaagagg
     4681 tactaaaaca tggataagct gattcttggt cgttatattc ccggagattc tctcattcat
     4741 cgtcttgacc caagaagtaa attattagcg atgattattt atattgtcat tatcttttgg
     4801 gctaacaatg ttgtgacaaa tttgttgatg ttgactttta ctttagcagt tgtttttttg
     4861 tcaaaaatca agttgtcttt ctttttaaat ggggttaaac caatgattgg tattatcctc
     4921 ttcacgactt tatttcagat gtttttctca caaggaggaa aagtaatttt tagttggtgg
     4981 ttcattagca taactgattt aggattgagc caagctattt taatttttat gcgtttcgtt
     5041 ctaattattt tcttttcaac gctgttaacg ttgacgacaa cacctttaag cctatctgat
     5101 gcagttgaat cattattaaa acctttaaca agatttaaag ttccagctca cgagatcgga
     5161 ctaatgcttt ctttaagttt acgttttgtg cctactttaa tggatgatac cacgcgtatt
     5221 atgaatgcac aaagggcccg tggagttgat tttggagagg gaaatttaat tcaaaaagtt
     5281 aaatccatta ttcctatttt aatccctctt ttcgcttcaa gctttaaaag agccgacgca
     5341 ttagctattg ctatggaagc tagaggttat cagggaggag aagggcgaac taaatatcgt
     5401 caattagact ggcagctaaa agatagttta gctattggaa tagtttcttt attgggtttg
     5461 ctactttttt tcttgaaaac ctctttgtaa tattttttag cacaaaactt ttctttatta
     5521 taagaagtga attgtacctc aaaagttaga tacaacatct aatgattgag gtacttttct
     5581 tcatttgagg aattgaaaac cgctatctca actatattaa tcctcccaat aataacaaat
     5641 cgaacgaaat ctaaaaggac tgagtcctgt tcaatacaga actaaattct tagtttaatg
     5701 atattatctc actttttaat gtagctaaga agaagagttt tatgattttt tacaacttct
     5761 tataatatca atgtagttgt aatattttta atatatc
//
LOCUS       DAUGOH010000064         5085 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUGOH010000064 DAUGOH010000000
VERSION     DAUGOH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5085
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.064"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(390..1025)
                     /locus_tag="VH957_001605"
     CDS             complement(390..1025)
                     /locus_tag="VH957_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEQ8559496.1"
                     /translation="MLTTNQIHKLLGVKEVYKAPDTLIKIILDKEKREDLFRQFLKYE
                     TDVSYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQA
                     WQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEWIGDGIEHIENPLIEWI"
     gene            complement(1025..1426)
                     /locus_tag="VH957_001606"
     CDS             complement(1025..1426)
                     /locus_tag="VH957_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559497.1"
                     /translation="MKNENFLGYDLAELLEEKLVGKRLKSIDDEKIVLADGTVIKIEL
                     NEGCGGCGNGWSELNITTENPNLESAVMGVEYTEKYSEWDDEFKIFVYMTDNSVIEIY
                     GYDGVGNGYYGYGFWVTVKNPGDLIESELED"
     gene            complement(1617..1952)
                     /locus_tag="VH957_001607"
     CDS             complement(1617..1952)
                     /locus_tag="VH957_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559498.1"
                     /translation="MDYLMIGIIVLSVVIFIMGFFILYYQAIIVNSMKNDFRRMRKEL
                     REELGFDSYNWSDSFRNMRRDIKSNKELISEINSLQIIKKAKEAKRLEELEQTKANVE
                     KEINKLNGG"
     gene            complement(1955..2227)
                     /locus_tag="VH957_001608"
     CDS             complement(1955..2227)
                     /locus_tag="VH957_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559499.1"
                     /translation="MTEEQELIKPLLEEIERKDDRLYMQSNVIAVLMTAVLMLLMISI
                     ALQNHYEPQITGLRTQLSRTQKQLKRASEDRTRQTKRIAELTGNGG"
     gene            complement(2230..2451)
                     /locus_tag="VH957_001609"
     CDS             complement(2230..2451)
                     /locus_tag="VH957_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559500.1"
                     /translation="MKIDYINFFEQVVPDWMRESNVKMQEVGFNTEAYWQWANQSIVA
                     ICEKYGNDSLINGQFHLIWEWLEDKANGG"
     gene            complement(2448..2843)
                     /locus_tag="VH957_001610"
     CDS             complement(2448..2843)
                     /locus_tag="VH957_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEQ8559501.1"
                     /translation="MIEFFLPMDKIPTTTHQQKKVTVINGKPHFYEPESLKNARDKFT
                     SLLAQHVPPSKLDGPIRLTVKWLFPKIKGSTNGQYKTTKPDTDNLQKLLKDCMTELGF
                     WNDDAQVASEIIEKFWADTVGIYVKVEEL"
     gene            complement(2836..3054)
                     /locus_tag="VH957_001611"
     CDS             complement(2836..3054)
                     /locus_tag="VH957_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559502.1"
                     /translation="MEIYKQRMIEEYKQLKKRAEKLSIVLNRYYLDELDFELSCPIEL
                     LQTQWHIMGAYLKILEQRFLVEGIYFND"
     gene            complement(3286..>5085)
                     /locus_tag="VH957_001612"
     CDS             complement(3286..>5085)
                     /locus_tag="VH957_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8559503.1"
                     /translation="IDKGIIYKPTKGAYDRTAGQLIQELQKNPNDIGAVLGDYKEEAG
                     AWIRFNPLDGNGVKNDNVTDFRYALVESDSMELGKQYALFKELELPIATLVHSGKKSL
                     HAIVKVDAKDYQEYRKRVDYIYQICKKNGLDIDTQNRNPSRLSRMPGIMRNGHKQFLI
                     DTNIGKTNYEEWYQWIEDLNDDLPEPETLADEWDNLPELAPELIKGVLRQGHKMLIAG
                     PSKAGKSFALIELSIALAEGQKWLGWQCEQGKVLYVNLELDRPSALHRFKDVYDAMGL
                     PPANVANIDIWNLRGKTVPMDKLAPKLIRRSLKKNYQAVIIDPIYKVLTGDENSADQM
                     AHFTNQFDKVATELGCSVIYCHHHSKGSQGGKKSMDRASGSGVFARDPDALIDLVELE
                     LTEDLIKARSEKAAAKIYQQALQEKALGYYQQEVTLDDLESRYQMQQHFDKAIKDIMV
                     KQPYLEAVKKAQHEVEIATAWRVDGTLREFAKFQPVNMWFSYPKHEVDTTGVLADIQL
                     EDSKPLWKKAKEARKSKEENLKERNQKLETAYSALFDGSTPVTVQEIREYLDLKSNKS
                     VENYIKEHDGYDVKKGVVFQISDNKETEKKENN"
BASE COUNT         1359 a         1098 c          807 g         1821 t
ORIGIN      
        1 tgaggagact taacaagcga ccgactcatt aggttagcgt ctctttcaag ggtctctatg
       61 agatgtggga tagtctttaa ttcttccaaa aaattattag cttttgttgt cggaatgttg
      121 cccatctaac tctccattca tgatataata ttgttgggta tttaatcatg gaggcgttcg
      181 catggacgtc tttttttgtg gagaaaagtc ctctctttcc tttgtttttt gacacaggcg
      241 tacgatgtca gtattagcgc cttaaataat agccagtgac cgataaccag cgttagattt
      301 tgttttggtg taaggaggtc ctcgtttcta tttttcaatt tcggtcaata ccaaccgcac
      361 gagtcgaacg tgcgggatac cgttattggt tatatccatt caattagtgg attttcaatg
      421 tgttctatcc catcaccaat ccactctttg acattaaatt ctcgctcaat atcttgagtc
      481 cttggcataa cgttaatatc actaaaactc agcatgtcgt cttttgtatt ttgcaaaaaa
      541 taaatgtttt taacttgtct tgttaaagag tcgccatgca ccaccacacc atttatccct
      601 cttatagaca tattaaagag tagaaacggt actgctttgt ccgataactc ttctacgtga
      661 taccagtatt tactcggacg ataagtaaat ggactgtcat ttaatcgttg ttcttgccat
      721 gcttggataa gtatcccacc cgtcccgact gctacctcgt agtattgatt accacttatt
      781 attttagata atagtgtact aaccgattta ggcgtaaagt cttgcttttt atttttgcgg
      841 tcagcttgtt cttcctcaaa atattgcata aaccagtcgt aagatacatc tgtttcatat
      901 ttcaaaaact gtctgaataa gtcctcgcgt ttttccttgt ctaaaattat ttttatcaac
      961 gtgtcaggcg ctttgtagac ttcttttact cccagcagtt tgtgtatttg atttgtagtt
     1021 agcattagtc ctccaattca gattctatta gatcaccagg attcttcaca gtaacccaga
     1081 aaccatatcc ataatatcca ttaccaacgc cgtcatatcc gtaaatctca ataacagaat
     1141 tgtctgtcat gtagacaaaa attttgaatt catcatccca ttcactatat ttttctgtgt
     1201 attcaacacc cattacagca gattccaagt ttgggttttc tgtcgtgatg tttaattctg
     1261 accacccatt tccacaacct ccacaaccct cgtttaattc aattttaatt actgtcccat
     1321 cggcaagtac aatcttttcg tcgtctattg atttaagtcg tttccctact aatttttctt
     1381 ctaatagttc agctagatca taacctaaaa aattttcgtt tttcattttg tacctacctc
     1441 acttattttt tgttttatct atcgtcttgc taaaagtaaa cgaaacgatc ccggcggcta
     1501 tataatacag tatgcaagat attacaatta gaatagtcgc aaaaacactt aatataacaa
     1561 cagcaactaa aattttagct aaacagctta ttaaagctaa acatccagat accacttcat
     1621 cccccattca acttattgat ttctttttcg acgtttgctt ttgtctgctc gagttcttct
     1681 agtcgtttag cttctttggc tttttttatg atttgcaaag agtttatttc ggatattaac
     1741 tctttatttg atttaatatc tctacgcata tttctgaaac tgtcagacca gttatagcta
     1801 tcaaaaccga gttcttctct caattcttta cgcattctac gaaaatcatt tttcatcgaa
     1861 ttaacaatta ttgcttgata gtaaagtatg aaaaatccca ttataaaaat tactactgat
     1921 aatactatta ttccaatcat taaataatcc atccttatcc cccatttcct gtcaattccg
     1981 caatccgctt agtctgtctg gtcctatctt cgctagcacg tttaagctgc ttttgtgtcc
     2041 tacttagctg tgtacgtagt cctgtgattt gcggctcgta gtggttttgt aaggctatac
     2101 ttatcatcag taacataaga actgctgtca ttaagacggc aattacatta gactgcatat
     2161 acaatctatc atctttccgc tctatctctt ctagcagcgg ttttattagt tcttgctctt
     2221 cagtcatcgt taacctccgt ttgctttatc ctccaaccat tcccaaatca gatgaaactg
     2281 cccattgatc agactgtcat ttccgtactt ttcgcagatt gcaacaatag attgatttgc
     2341 ccattgccaa tacgcttcag tattaaatcc aacttcttgc attttgacat tactctctct
     2401 catccagtca ggaaccactt gttcaaaaaa attaatataa tcaattttca taactcttcc
     2461 acctttacgt atattcctac tgtatcagcc cagaacttct caataatttc cgaagcaacc
     2521 tgcgcatcat cattccaaaa tcccaattcg gtcatgcagt ctttaagcag cttctgcagg
     2581 ttgtcggtat ctggttttgt cgttttgtac tgtccgtttg tgctgccctt gattttggga
     2641 aatagccact tgactgtcag acggatagga ccatctaact tactgggtgg tacatgctga
     2701 gccaaaagac ttgtaaactt atccctagca tttttcaaac tctcaggctc gtaaaagtga
     2761 ggcttgccat ttatgacagt cactttcttt tgctgatgag ttgtcgtcgg gattttatcc
     2821 ataggcaaaa aaaattcaat cattaaaata aatcccttca accaaaaatc tttgttctag
     2881 aattttcaaa tacgctccca taatatgcca ttgcgtttgt aaaagttcaa ttgggcaaga
     2941 taattcaaaa tctaactcat caaggtagta tctgtttagc acaatagata gtttttctgc
     3001 gcgttttttt aactgtttat attcttcaat cattctttgt ttgtaaattt ccatttttac
     3061 ctcatctcca atttgtgttt tttatatgcg cctttgtcaa atatgggaca aaggacagag
     3121 ggggcgtagc tcagtcgccc ctcttccttt tccctttgac ttttgacgaa ggaaaaacat
     3181 tttataataa ctctgaaaga gttataggct gtattttctt agaaattaac tagtattttt
     3241 ctgatttgag aaaagaaaat aacgtaattt ttctttagaa ttcttctagt tattttcttt
     3301 cttttccgtt tctttgttat cagaaatttg gaacacaaca ccttttttga catcgtaacc
     3361 atcgtgttcc ttgatataat tttcaacgct tttattggat tttaaatcca agtattcacg
     3421 aatttcttgc actgtaaccg gtgttgaacc atcaaataag gcgctataag ctgtctcaag
     3481 tttttggttc cgttccttga gattctcttc tttacttttc ctagcttctt tagctttttt
     3541 ccaaagaggt ttactatctt ccaactgaat atcagccaac acgccagttg tatccacctc
     3601 gtgcttggga taactaaacc acatattaac tggctgaaac ttcgcaaact cacgtagcgt
     3661 tccatcaact cgccacgctg tggcaatttc tacctcatgc tgggcttttt tgacggcctc
     3721 aagatatggc tgtttaacca tgatatcctt gatagctttg tcaaaatgtt gttgcatctg
     3781 ataacgactt tctaggtcgt ctagcgttac ttcctgttga tagtatccta gagctttttc
     3841 ctgcaacgct tgttggtaaa tcttagcagc tgctttttct gagcgtgcct tgataaggtc
     3901 ttcagtcaac tcaagctcca ctaagtcaat caatgcatca gggtcacgag caaatactcc
     3961 agaaccactt gccctgtcca tagatttttt gccaccttga cttcctttag aatggtggtg
     4021 gcaataaatt acgctacatc caagttcagt ggccacctta tcaaattgat ttgtaaaatg
     4081 ggccatctga tcagcactgt tttcatcgcc agtgagaact ttataaatag ggtcgataat
     4141 aacagcttgg taatttttct tcagtgagcg tctgataagt ttaggtgcta atttatccat
     4201 tggtactgtt tttccacgga ggttccaaat gtcaatgttt gccacattag cgggaggtaa
     4261 tcccatcgca tcataaacat ctttaaagcg gtgcaaagct gatggtctgt ctagctccaa
     4321 attgacatag aggactttcc cttgttcaca ttgccaacct aaccatttct gtccctcagc
     4381 caaagcaata gataactcaa tcaatgcaaa tgacttaccg gcttttgatg gtcctgcaat
     4441 tagcatttta tgtccttggc gtaacactcc tttaattaat tcaggagcca gctctggcaa
     4501 attatcccat tcatcagcta gcgtttctgg ctctggtaaa tcatcattta aatcttcaat
     4561 ccattgatac cattcttcat aattggtttt accaatattt gtatcaatca aaaattgctt
     4621 gtgaccattt cgcataatac ctggcattcg tgatagacga cttggattac gattctgtgt
     4681 gtcaatatca aggccgtttt tcttacagat ttgatagatg taatcaaccc gtttgcggta
     4741 ctcctgataa tctttagcat ctactttgac aatagcgtgt aatgattttt taccgctatg
     4801 gaccaatgtc gctattggca attctagttc tttaaataaa gcatactgct taccaagttc
     4861 catactatcg gattcaacca aggcatacct aaagtctgtt acattgtcgt ttttgacacc
     4921 attgccatct aaagggttaa atcgtatcca tgcaccagct tcttctttat agtcaccgag
     4981 gacagcacca atgtcattag gatttttttg taattcttgg ataagctgac cagctgtcct
     5041 gtcataggct ccttttgttg gtttatagat aatgccctta tctat
//
LOCUS       DAUGOH010000065         4822 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUGOH010000065 DAUGOH010000000
VERSION     DAUGOH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4822
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.065"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(56..298)
                     /locus_tag="VH957_001613"
     CDS             complement(56..298)
                     /locus_tag="VH957_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8559504.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMGDVLDYLVQRLT"
     gene            complement(291..1298)
                     /gene="plsX"
                     /locus_tag="VH957_001614"
     CDS             complement(291..1298)
                     /gene="plsX"
                     /locus_tag="VH957_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEQ8559505.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQMINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            complement(1401..2156)
                     /gene="recO"
                     /locus_tag="VH957_001615"
     CDS             complement(1401..2156)
                     /gene="recO"
                     /locus_tag="VH957_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEQ8559506.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            complement(2342..3304)
                     /locus_tag="VH957_001616"
     CDS             complement(2342..3304)
                     /locus_tag="VH957_001616"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8559507.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            complement(3557..4753)
                     /locus_tag="VH957_001617"
     CDS             complement(3557..4753)
                     /locus_tag="VH957_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8559508.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
BASE COUNT         1521 a          994 c          741 g         1566 t
ORIGIN      
        1 aaggttcgtt tttaaagaat aataaaaaga gcttacgctc tttttattat tctaactaag
       61 tcaaacgctg aactaaataa tctaaaacgt ctcccataaa taccatatcc tcaacatctt
      121 catcaggaat agcaatatga aattcatctt caacattaat aataaattca actagttcaa
      181 tagagtcaac cgctaaatca ttttttaaat gtgtttgttc tgtaatagct acactcaaat
      241 agcttctttg cttctgaatt aagttaatca gcctttcaaa aatctcctgt ctagtcattt
      301 acttgagtct ccttagcaaa ttcttctact aattgtccga ccacgttagt gtctagcatc
      361 gtacgtactt gttttatcgt tgaaaaaata gcttttacat cactagaacc atgagacttt
      421 acaacaggtg cctttaaacc aaataaaact gcacctccag cactagagta gtcaagagtc
      481 ttcttcatct cgtaaagact acttttaagt agactagccc caattttagt cttaataccg
      541 ccgctattaa tcatctgttt cagttgcccc ataatgctaa tagctgttcc ttctattgat
      601 ttcaacactg cgtttcccgt gaaaccatct gatacaataa catctgcaac acctgacata
      661 agttctcgcg cctcgacatt accaacaaaa gatattgtat tatctgctgt taaaagttca
      721 taagtagcct tacgaagggg atctcctttt gtttcttctg taccattgtt taatagacca
      781 acacgtggat tagcaatccc acgtacattc ttagcataga aagagcctaa aatagcatat
      841 tgatgtaaat gttttgccgt attttcagca ttagctccaa gatccaacat atcaaatcct
      901 aatccggtta ctgtgggaat agttgataat aatcctggac gatcaactcc cttgatacgc
      961 cccacaacaa acaaacctac agctaaaaga gcacctgtat tacctgctga aataatggca
     1021 tctgcttttc cttctttcac tgccttagct gctaaaacca ttgaagcctt ctttttacgg
     1081 cgaacagctt ttgcaggttc atcatctgac ataatttttt catctgtatg aataatagca
     1141 acacgatctg attgaataag ataggagtta atctttgtct gatcaccgta aagttgaatt
     1201 tcgatatctg aaaatgcttc tattgcttga ttaacaccct caacaatagc tttaggagcg
     1261 ttatctccac ccatagcatc tattgcaatt ctcttcattt ccactccttt aattatatct
     1321 tgtgttctta cacaatctat taatagtatt tttattatag catattctga aaccaattcc
     1381 cataaacgaa agaggcccta tcatttcata atatctcccc acttaactaa attatcaatg
     1441 aatgttttac tttttaattt gattcctaca tagtcgtgat acaactcatc aatgaactga
     1501 cgaagcttct ttttgatgtc tttattcaat gaaatagttc tcaaatcatc aaatgtgatt
     1561 ttttgaaatc gactcaacaa gtagataaca tttggatcta aatgattacg tcggttgtct
     1621 ttgtaataat gttcagaaca aagtacagct gaaaaacgat gggaaaaatc aagcggtaaa
     1681 tcagtgcgat gacaaatggc acactcatga aagtttagac taataccaaa acgatctaat
     1741 atctgaattt caaaaatatt tgtcaaaatt tcataatcta ggccctcttc catcaaatca
     1801 agtgtttttt tcaaaaacgt aaacaaatgc gaatctgatt cattatctgc aatcgcagca
     1861 tcagctaatg ctaagacata actagcatag gctaatcgaa aaatatcatt attaatatac
     1921 cgataagtgt taacgttact atagtcaaca acataagaca agcctgtatc atttaacttg
     1981 aaaataaaat cagcaatcgt tagtggttga atgattgagg acattttgga acgactaata
     2041 tgtttcacga aaaacatctg cttacctgct acttcagtaa atattttgac taatttatca
     2101 tcttctcgat aattcctatt aaaaagaaca atgcctagtg attctgttag ttgcatatta
     2161 cctcgtcgta tttttctttt accttttatc ttagtttaca ataaactgtt attatctttc
     2221 ttattatacc caaaatcctt tagaattgca tagttcatcc cacaataatt aataccacat
     2281 tacctttaca ttttattcaa gtcaaaaagc ccgagatcta ttatctcagg cttcgttaag
     2341 tttaattgcc catctcaaat aaaggtgaca acggacgttt ttcatgaata cgaataatcg
     2401 cttctgcaac caaatcagca attgaaattt gttcaatttt atcaataaga cgttcttttg
     2461 gcagataaat agtatcaaga acaattagtt tttcgatagc cgaacgttga atattatcaa
     2521 gtgctggtcc agaaagaacg ggatgcgtac atgacgcata cacagctgtt gcccccgctt
     2581 cagcaagcgc atctgctgca tggcaaatag tccctgcggt atcaatcata tcgtcaatca
     2641 agatacattt cttgcccgaa acatttccga taatattcat cacttcactg gtgttcatct
     2701 tatccacact acgacgctta tcgataattg caattggtgt ttggaggaat tgtgctaatt
     2761 tacgcgcacg agtcacacca ccatggtcag gactaacaac gacaacatct tcacccacta
     2821 aaccatgacg atcaaaatag tctgcaatta aaggtgcacc catcaagtga tcaactggaa
     2881 tatcaaagaa cccttgaatt tgagcagcat gtaaatcaac cgttaataag cgatctacac
     2941 cagcaacttc taacatatta gcaactaatt ttgaagtaat aggttcacga gaacgcgctt
     3001 tacggtcttg gcgtgcatag ccgtagtaag gcatcacaac tgaaattttt tcagcactag
     3061 cacgctttaa agcatcgacc ataatcaaaa tttccattaa attgtcattg acaggtgagc
     3121 tagttgattg caaaataaag acatgatgac cacgaattga ttcttcaata tttacttgga
     3181 tttcaccatc tgaaaactgg cgaaccgtag actttccaag ttgaataccc attgcagacg
     3241 caactttttc tgctaattcc ttgtttgacg ataaagcaaa caattttaaa tcagaataag
     3301 acattttttc ctccaaagtt ttaatcctat accattttaa cgcttttcaa gtgaattatc
     3361 aaatgaaatt gaaaaaccgt taaagaatgt attaaatata ccttttatcg actttatata
     3421 cttctcttat attatacata agcgattggc caaacaactc tcttataaat taactatatc
     3481 gtcaatactc tcagaactat tccacaatag gagtaatcaa aaaggttaga acaactgttc
     3541 taacctaaat aatatgttag tgtggataaa taaatgtaac acctgttgga ttaaaccagc
     3601 cacggtggtc agcaatgtac tgtctaccac tgtagttaga ctccatcaca cgaatacttg
     3661 aggcactttg aacctcaact acaacggcga catgtccata accaccatcg ttccaaacgg
     3721 caatcgcacc taccatcggc gttgaaccag tacgataacc agctgcttga gcactataag
     3781 cccattgacc accatttccc caattatttc ctgcccaagg agctaaagat ttagctcccc
     3841 atgtgcattg tccaactgga taagtattag aagaatcata tgatgtttgt ggtcctgcag
     3901 aaggagctgc cggagccgtg agtgcagctg gttcaatagc attactactt tgcgctgccg
     3961 gagtagcttg tggtgctgga gtaatagcag attttgctgc ttcaacagat gctgcttgtt
     4021 gtgcagcctg ttcttgtgcc ttaactttag cagcctgttc ttgtgctaag gcttcagcag
     4081 cagctttttc tgcagcttct ttttgagcta ccaaattagc tttatcttca gtagcagatg
     4141 ctaattggag agctaaattt gcagttgcag ctaccaaatt agcttgttga gtacgtaatg
     4201 tattttggtt ttcttcagcc attgccatat tagcggcaat ggtattaata gctgtttggt
     4261 tagcagcttg cttttcttca agggaaactt tatcagcttt ttgttgttct aacaatttag
     4321 cgttagcaga gacagctcta ttaattgcta ctaaacggtt tacaacatca gaaattgatt
     4381 tagaattcaa aagtgcatta atataaccag aagtttcatt gtttttataa gcactacgag
     4441 cttgattttt taatttttca ttacgagcaa caatttgact tgttagagcc ttaatttctt
     4501 gctcaaatcg ctttgaaagc gcctcaagtt ctgtatttct tgcggtcagt ttatcttgtt
     4561 cagattgtag tgaacttact tgagcctgta acgctgaaac ttgattctgt gcagcttttt
     4621 gctctgtagt cagatttgag ataatagaat cttgcttagc aatcttagta cttaaatcct
     4681 ccgctcctac agttgtagct gctccgaggg taacaccact tacaagaact gctgataaaa
     4741 ttcttttttt cataataaaa aaactactcc ttttcgataa gacatcttat attttaccaa
     4801 aaaaaaaagt atttaatatt ac
//
LOCUS       DAUGOH010000066         4645 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUGOH010000066 DAUGOH010000000
VERSION     DAUGOH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4645
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.066"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..360
                     /gene="tilS"
                     /locus_tag="VH957_001618"
     CDS             <1..360
                     /gene="tilS"
                     /locus_tag="VH957_001618"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8559509.1"
                     /translation="DEKMLEYDSNLCYRDYCFSFMPKSNEDQGQVSIPLFSLSSIKLR
                     SRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKAC
                     KHDIMLAKLYIDKLEKG"
     gene            365..907
                     /gene="hpt"
                     /locus_tag="VH957_001619"
     CDS             365..907
                     /gene="hpt"
                     /locus_tag="VH957_001619"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEQ8559510.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            929..2908
                     /gene="ftsH"
                     /locus_tag="VH957_001620"
     CDS             929..2908
                     /gene="ftsH"
                     /locus_tag="VH957_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEQ8559511.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            3234..4625
                     /locus_tag="VH957_001621"
     CDS             3234..4625
                     /locus_tag="VH957_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8559512.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLIFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT         1551 a          667 c          903 g         1524 t
ORIGIN      
        1 gatgaaaaaa tgttagaata cgatagtaac ttatgctaca gagattattg tttttcattt
       61 atgccaaaaa gtaacgaaga tcaaggacag gtaagtatac ctttatttag tttatcgtct
      121 attaaattaa gaagtcgcca atctggagat tatatttctt ttggtcactt ttcaaaaaaa
      181 ataagacgtt tatttataga tgaaaaattc acaatagctg aacgccaaaa tgctattatt
      241 ggagagcaag atgagcagat tatatttgta ttgataggta ataaaactta tttgagaaaa
      301 gcttgtaaac atgatataat gttggctaaa ctgtatattg ataaattaga aaaagggtga
      361 cagcatgctc gagcaagata ttcaaaaaat tctttactct gaaaatgata ttattcggaa
      421 aactaaaaaa ttaggagaac aattaacaaa agattatcaa gaaaaaaatc cgcttatgat
      481 tggtgtatta aaaggatcag ttccttttat ggcagaacta atgaaacaca tcgatactca
      541 tgttgaaatt gattttatgg tagtatcaag ttatcatggc ggtacatcta gcagtggtga
      601 agttaaaatt ttaaaagatg tagataccaa tattgaagga agagatatca taattgttga
      661 agatattatt gacaccggtc gcaccttaaa atatttacga gatatgttta agtaccgtaa
      721 agctaatact atcaaaattg caacactgtt tgataaacct gaaggtcgtg ttgttaaaat
      781 tgaagcagac tatgtttgtt acaatattcc aaatgaattt atcgtaggct ttggtttaga
      841 ttacgcagaa aattatcgca atcttcctta cgtaggtgta ttaaaagaag aagtctattc
      901 aaaatagaaa aaggtcaatg tttactgtat gaaaaataat aaaaataatg gttttgttaa
      961 aaattctttt atatatatat tgatgattat tgttgtcatc acaggatttc aattttatct
     1021 taagggaacc agcacacaaa gccaacagat tagttattcc aaattaatta aacatcttaa
     1081 ggctggagat ataaaatctt taagttatca gcctagcggt agtattattg aagttaaagg
     1141 gaaatatgag aaacctcaaa aagtgacagt taattcagga ctatcatttt taggtggaag
     1201 agcttcaaca caggtaacag agttctcatc tttagtatta cctagtgata ccatcttgaa
     1261 agaaatgaca gcagcagctg ataaaaatgg aacagagctt acagttaagc aggaaagttc
     1321 aagtggtact tggattacct tcttaatgag ctttttacct attgttattt ttgctgcttt
     1381 catgatgatg atgatgaatc aaggtggtgg aggagctcgt ggtgctatga gtttcggcaa
     1441 aaataaggca aaatctcaat caaaaggtga tgttaaagtg agatttacag acgttgctgg
     1501 tgccgaagaa gaaaaacaag aattagtaga agttgttgat tttttgaaaa atcctaaaaa
     1561 atataaatca ctaggagcac ggattccagc gggagttctt ctagaggggc ctccaggtac
     1621 tggtaaaaca ttactagcta aagctgtagc aggtgaagct ggagtgccat ttttcagtat
     1681 ttcaggttca gattttgtcg aaatgtttgt cggtgtaggt gctagtcgtg ttcgttcttt
     1741 atttgaggat gctaaaaaag ctgagcgtgc gatcatcttt atcgatgaaa ttgacgctgt
     1801 aggccgtcgt cgtggtgctg gcatgggagg cggtaacgat gaacgagaac aaacccttaa
     1861 ccaattactc attgaaatgg atggttttga gggtaatgag aacattatcg ttattgctgc
     1921 aactaaccgt agtgatgttt tagatccagc tttactaaga ccaggtcgtt ttgatcgtaa
     1981 ggttttagtt ggtcgccctg atgttaaagg acgtgaagcc attttacgtg ttcatgctaa
     2041 aaataaacca cttgcaaatg acgttaattt gaaagtagta gcccaacaga ctccaggttt
     2101 tgtaggtgct gatcttgaaa atgttttaaa tgaagctgcg ttagttgctg ctcgcagaaa
     2161 taaaattaaa attgatgcta gtgatattga tgaagctgaa gatcgtgtta ttgctggacc
     2221 atcaaagaaa gatcgcacta tttcgcaaaa agagcgagaa atggttgctt atcacgaagc
     2281 tggtcatact attgttggtt tagttttatc taatgcgcgt gtagttcaca aggtaactat
     2341 tgtacctcgt ggacgagcag gtggttatat gatcgctctt ccaaaagaag atcaaatgct
     2401 tctttctaaa gaagatctga aagagcaatt agcaggattg atgggtggtc gtgttgctga
     2461 agaaattgtt tttaatgctc aaacatcagg tgcgtcaaat gactttgagc aagctactca
     2521 gatagcaagg gccatggtta cggaatatgg tatgagtgaa aagcttggac cagttcaata
     2581 tgaaggtaac catgcgatga tgccaggaca gatctctcct gaaaaagctt actctgccca
     2641 aacagctcaa atgattgatg atgaggttcg tgaactctta aatcaagctc gtaatcaagc
     2701 agctgatatc atcaatgaga atcgagatac tcataaattg attgctgaag ctcttctcaa
     2761 atatgaaact ctagacgctg cacaaattaa atcaatttat gaaactggta aaatgccagt
     2821 tgatttagaa actgatgata atgaagctca tgcgttatct tatgacgaaa ttaaaaataa
     2881 aatgacagaa tctgaatctg cagaatgaga taaaaaagct gaacttatag attaagttca
     2941 gcttttttat caacacaata tccttgtaaa cgttatgaat tgtaataggt gcctaattgc
     3001 tagaaatgag aagatgacat actttttttc tttattactt aaagtgagaa agacttttgt
     3061 atttaaaact agaaaattgt taaagccatt tgaaaaaatc tattagtgtt ttcttagaat
     3121 aatagaagaa cagaagatag caaaagtttc agtcaaccaa taagatgaaa tttacaatca
     3181 ttactaacta tgatacactt agtagaaaat catttactat agaaggtgat aacatgacta
     3241 tttttcgtaa aaaaaagaaa tattccaata aaacagaaat gcaaaggcac ttcaaagtta
     3301 ttgatttaat ttttttaggc ctaggttcaa tggttggaac aggtatcttt acagttactg
     3361 gcataggcgc tgctaagtat gcaggtcctg ctttaacaat atcgattatc atttccgcga
     3421 ttgctattgg aattttagcc ttattttatg cagaatttgc gtctcgtatg ccttctaacg
     3481 gtggtgctta tagttatgtt tatgcaacct tgggagagtt tccagcatgg cttgttggct
     3541 ggtatattat tatggaattt ttaacagcta tatctagtgt tgctgttggc tggggaagtt
     3601 atttaaaagg attacttgcc aattataata tagtattacc aaacgcttta aatggcacgt
     3661 tcaatcttaa gaatggaact tacatagata ttcttcctgt tttagtgatg tttttcgtga
     3721 cagggattgt cctaatgaat tcgaaattag ccctgagatt caatagtttt ttagttattt
     3781 taaaattttc agcactggct ttatttatct ttgtaggcat tttttttatt gatcacaata
     3841 attggtctca ttttgctcca tatggtgtag gacaaattac tggaggtaaa acaggtatat
     3901 ttgctggtgc ttctgttatg ttctttgcat ttttaggatt tgaatctatt tcaatggcag
     3961 ttgatgaagt gaaagaacca caaaaaacaa tccctaaagg catcatttta tctttgatta
     4021 ttgtaacagc actctatata gttgtcacca ctattttaac gggaattgta cactacacta
     4081 aattaaatgt tccagacgcg gtggcttttg ctttaagaaa tattagactt tattgggcag
     4141 ctgactatgt gtcgatagtt gctattttga ctcttattac ggtatgtatt tctatgacct
     4201 atgcattagc tagaacaatt tacagtatta gtagagatgg tttattacct aaatcacttt
     4261 atactctcac taaaaaaaat aaagtgcctc aaaatgctac tcttgtcact ggactacttg
     4321 ctatgatttg tgcgggaata tttcctttat cgagtctagc agagtttgtt aatatttgta
     4381 ctttagcata tttaattatt ctgtcgggtg caattattaa actcagaaga atagaaggag
     4441 aaccaaaagc aaatgaattt aaaactcctc tagtaccatt cctaccaatg ttggcaatta
     4501 tcatttgtct atcatttatg agccaatata aagcttttac ttggattgct tttgctattg
     4561 ccacaattat tgggacatta atctacttag cttatggtta tactcattca atagaaaata
     4621 aataatgttt tgataataag atttg
//
LOCUS       DAUGOH010000067         4576 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUGOH010000067 DAUGOH010000000
VERSION     DAUGOH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4576
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.067"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(293..656)
                     /locus_tag="VH957_001622"
                     /pseudo
     CDS             complement(293..656)
                     /locus_tag="VH957_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1077..1610)
                     /locus_tag="VH957_001623"
     CDS             complement(1077..1610)
                     /locus_tag="VH957_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEQ8559513.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1690..2466)
                     /gene="recX"
                     /locus_tag="VH957_001624"
     CDS             complement(1690..2466)
                     /gene="recX"
                     /locus_tag="VH957_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEQ8559514.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2581..3936
                     /gene="rlmD"
                     /locus_tag="VH957_001625"
     CDS             2581..3936
                     /gene="rlmD"
                     /locus_tag="VH957_001625"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8559515.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGENIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
BASE COUNT         1396 a          725 c          947 g         1508 t
ORIGIN      
        1 ctatttagta actttggtta aagtaatcga actaacttgg ttaattgtat tttaatgata
       61 aaaagcttaa atttattata caacaaattt aagcttttta ttgtttcttt ttaattgcag
      121 attgaggttt aaaagacact ttacaatgtt ctcaagtcat gtgttgttgt aggttgtatg
      181 cacatattac aaatcccatt atagaagaaa ttgtttaatt aatggatagt aatggatggt
      241 atggagatct taatgtggtt ttaatggtaa ttttagcagt tatagtaaga caaaaggtga
      301 cttggaaaag cttatgcaga cgattcttaa ctcccacaat atcttctgtc agattttatt
      361 agacttcttc tcagtgtcaa ttttgtctgt tttacgaacg tgcaggctat tcaattgctt
      421 cttagcttct aaaggattaa accgagtata agcgtagcca ttatctgcga aaaaacctga
      481 agacgatgag aatagacatt aatcgcttta aggataatct cagggttatg gacggttttc
      541 aagtttctaa gaagacgatt gaggccgatg gtatcgtttt gtcttgaatg attccttatt
      601 ttagtggttt cattttcaat acacgacgtc aagcgtccta catactttga taaaattcta
      661 cctaaaagag gtgacttgtc agttttgatt acaacatcaa gtgccaaaag actttgcgac
      721 ttaacaagac acttctactt taacgcaaag aaaaagtagt gagtactctc tttcgtcgga
      781 gatttcctcg ctactaaact tagtattttt tgatactttc cttaggtagt gcttaaggca
      841 gcgactttct ttggaattcc atgccttatt tttgagatcc taggctcaaa aatgccaagt
      901 ggcgtcaaca ttaacattga cgccactttt accacaacga aaaacatctg ttttggctca
      961 ctccacacgc agaaatagga aattggatgt caaatcagca gagctgttca tgctttttga
     1021 gcctaaaact gagtttgtct gcgttctgag cactccttgg gagtgctgga caactcttaa
     1081 cgattcttca gttcaagata acgtttgtac caaatagtga tataggcctt ggaaaatggt
     1141 cctttttcat gattaatcca atcaaccaat attttgacat tttcttttag gataaagtcc
     1201 atatcggctg aatactgcat ctctttttta tgaatctcgt attcatcaac atcaagtaat
     1261 ctcttttcac catccgcaaa gactttgaca tctaaatcgt aatcaatgta tttaagggcc
     1321 tcagtgtcca tcatgtatgg actagctaag ttacagtaat aagagacgcc attatctcga
     1381 atcatggcta taatgttaaa ccagtatttt ttatgaaagt aaacgattgc aggttcgcgg
     1441 gtcacccatc gtctaccgtc actttctgtg acaagagtgt gatcattaac tccaatgagg
     1501 gcattttcag ttgtttttag taccatagta tcgcgccaag tacggtgcaa actaccatca
     1561 tgcttataac tttgaattgt aataaagtcg ccttctttag gtaatttcat gccttaccaa
     1621 ctttctacaa ttaaacttat cctctatagt ctatcataaa tgtgtgaaaa aatcacttct
     1681 tttgtcagtc tataaataat ttcttaactt gcaattaatg tcgtcgctgt tgtagccttt
     1741 tcggtagaga gcctgataga gcttttgctt taaggtataa ccatcatatt tgcgactgag
     1801 tttacgatat tgtttgtcta attctttgtc aagaagatct tctatttctt gattatcttg
     1861 gtcaaaatta aggtgattga ggctatgttt agctagatcg taagaaaagc ctttggtcag
     1921 taatgcttgg gtgattttat ctttcaaggc ttttggtggc aatttttctt gatatttgtc
     1981 aaagagtttt tggcttactt tttgagcgag ttggctaaag tcagtttgag ataagatagg
     2041 atcaatgtca tgacttgcaa tgcctttttg taataatttt tgttttaaga cttggggacc
     2101 tttatcacca tttaactgat tttggcgaat gtaggtatca gccaatttgg tgtcgtctat
     2161 ccattgttct tcttggagtt gagtgatgat gtcagcaata atgtgttctt caatctcatg
     2221 cttgcgcagg taatcagcaa cttgcttgtt gctgcgttgt tgaaaggaaa gaaaataaag
     2281 ggctaaattt ttgccgtagg acagttgggc aaaatgtttc atgtcttcaa gctgatcatt
     2341 gtcaaggact ttatctttac tcaacataaa ccgaacaata gtatcttctg ttacataaag
     2401 ggattcgtca ttatccaatt cgataaggta gaggcgtttt ttcttttcaa ttttagtgat
     2461 tttcatactt tgattatatc aaaaatggta aaatagaaga tgaaaatact gctaaaaatg
     2521 tgttgcttgt gaatgctttt ggtggtgaga ttaggatatt agaggaagta aggggaagag
     2581 atggtcgtaa aggttaaaca gaaaattcct ttaaaaatta agcgaatggg aattaacggt
     2641 gaggggattg gtttttatca gaaaactttg gtatttgtcc ctggtgcttt aaagggagaa
     2701 aatatttttt gccaaatcac ggcggttaaa cggaattttg cagaggccaa gctgttaacg
     2761 gtaaacaagg cttctaagaa tcgtgtcaaa ccagcttgtt ctgtttatga aacttgtggt
     2821 ggttgccaaa tcatgcatct agcctatcct aaacagctag atttcaaaga tgatgtgatt
     2881 aggcaggccc ttaaaaagtt caaaccaact ggctatgaac aatttgagat tagaccgact
     2941 ttaggaatga aaaagccaga tcactatcgg gccaaattgc agtttcagtt gcggtcattt
     3001 ggcgggacgg tcaaggctgg tttattttcc cagggaagtc atcgcttggt tcctattgac
     3061 aattgcttgg tacaggatca actaacgcaa gatattatca ataagattac gcagttagtg
     3121 gacaagtaca agttgcccat ttacaatgag cgcaagattg ctgggattcg gacgataatg
     3181 gttcgtaagg cacaggctag tgatcaggta cagattattg ttgtgagtag caaagaagtt
     3241 cggttagcga atttcattgg cgaattgact aaggcatttc ctcaggttaa aacggttgcc
     3301 ttgaatagta atcgttctaa atcgagtgag atttatgggg acgaaacgga aattctatgg
     3361 ggacaagagg cgattcatga agaagtttta gactatggat ttgcgttatc accgagagct
     3421 ttttaccaac ttaatccaca gcagacagaa gttttgtatg gtgaggtggt gaaggccttg
     3481 gatgtaggga gcaaagatca tattattgat gcctattgtg gggttggctc gattggcttt
     3541 gcttttgcag ggaaggtcaa gtctgtgcgg gggatggata ttatcccaga agcgattgaa
     3601 gatgcacaaa aaaatgccaa agccatgggc tttgacaacg cttactatga ggcagggaag
     3661 gcagaggata ttattcctaa atggtataaa caaggttacc gcgcggatgc catcattgtg
     3721 gacccaccaa gaactggttt agatgataaa ttattaaaaa cgattcttca ttaccagcct
     3781 aaacagatgg tttatgtgtc ttgtaatacc tccactttgg cccgcgactt ggtgcagcta
     3841 acaaaggttt acgatgttca ctatatccaa agtgtagaca tgttccccca tacagctagg
     3901 accgaggctg tcgtgaagtt acaaaaacgt gtatgattga gtggcaataa caactcaagt
     3961 tttataagct caggtaatgg gtttgagcaa tagcttgaca tagtagggat gtcaaaaacg
     4021 gtttactaag catagtcata ttattgataa ctctatgttt attttagaaa cattcatggt
     4081 taaaaaagtt tgttagtttg tcactaagta gggtctattt gaagagcaag tacacacaga
     4141 caatattagg ggaattgatt gttgaaaaat agctgttttt tgctataaat tagaaaactg
     4201 agtggtcagg aggttacatt accagaagtt attttagtat gctaatatga acgatgatat
     4261 agaggattta tcctgattta atcttttaag ctgtaagaaa cctttgcaaa aactgtaggc
     4321 tgtgtgagtc tttatgtgtt agatattaaa gataaatgca acactttttt ataatgagat
     4381 caacaactga taaatctgag ttgataacca gtaaaatgat cggaatatag aaaagttact
     4441 taatcaagct tttcgtaatt taactgttag aatgacagaa cttatgataa aataaagaat
     4501 atgattaaaa tgaaaaagct cagtttatct attacggagt tcgaaatgaa aagaaaatcg
     4561 agatgtgata acatat
//
LOCUS       DAUGOH010000068         4292 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUGOH010000068 DAUGOH010000000
VERSION     DAUGOH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4292
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.068"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..787
                     /locus_tag="VH957_001626"
     rRNA            <1..787
                     /locus_tag="VH957_001626"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            839..911
                     /locus_tag="VH957_001627"
     tRNA            839..911
                     /locus_tag="VH957_001627"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ala,seq:tgc)
     gene            1210..4112
                     /locus_tag="VH957_001628"
     rRNA            1210..4112
                     /locus_tag="VH957_001628"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4198..>4292
                     /gene="rrf"
                     /locus_tag="VH957_001629"
     rRNA            4198..>4292
                     /gene="rrf"
                     /locus_tag="VH957_001629"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1208 a          892 c         1216 g          976 t
ORIGIN      
        1 tgaggctcga aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgccgtaaa
       61 cgatgagtgc taggtgttag gccctttccg gggcttagtg ccggagctaa cgcattaagc
      121 actccgcctg gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca
      181 caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac
      241 atcccgatgc ccgctctaga gatagagttt tacttcggta catcggtgac aggtggtgca
      301 tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc
      361 tattgttagt tgccatcatt aagttgggca ctctagcgag actgccggta ataaaccgga
      421 ggaaggtggg gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta
      481 caatggttgg tacaacgagt cgcaagccgg tgacggcaag ctaatctctt aaagccaatc
      541 tcagttcgga ttgtaggctg caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg
      601 atcagcacgc cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga
      661 gagtttgtaa cacccgaagt cggtgaggta acctattagg agccagccgc ctaaggtggg
      721 atagatgatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac
      781 ctcctttcta aggaaatgga acacgtttat cgtcttattt agttttgaga ggtcttgtgg
      841 ggccttagct cagctgggag agcgcctgct ttgcacgcag gaggtcagcg gttcgatccc
      901 gctaggctcc atcaggatac aatcctacta aacttaatac aagtgaagtt gaacacgcaa
      961 ctcacttcct aggaaaatag acaatcttcc cttgtgtgca aggcccacat ggtcagattc
     1021 ctaattttct acagaagttt cgctaaagcg agcgttgctt ggtatcctat ataatagtcc
     1081 attgaaaatt gaatatctat atcaaattcc acgatctaga aatagattgt agaaaagtaa
     1141 caagaaaata aaccgaaaac gctgtgacta tttaataagt tttctagttt aaaaaaacta
     1201 ggttaataag gttaagttaa taagggcgca cggtggatgc cttggcacta gaagccgaag
     1261 aaggacgtga caaacgacga aatgctttgg ggagctgtaa gtaagcgctg atccagagat
     1321 gtccgaatgg gggaacccac taactaatgg ttagtatcca taactgttaa ggttatgaga
     1381 aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc aaacgcgatt
     1441 gccttagtag cggcgagcga aacggcagga gggcaaaccg aagtgtttac acttcggggt
     1501 tgtaggactg cgacgtggga ctttaaaagg atagaagaat tacctgggaa ggtaagccaa
     1561 agagagtaaa agcctcgtat ttaaaattct tttgagccct agcagtatcc tgagtacggc
     1621 gagacacgtg aaatctcgtt ggaatctggg aggaccatct cccaacccta aatactctct
     1681 agtgaccgat agtgaaccag taccgtgagg gaaaggtgaa aagcaccccg ggaggggagt
     1741 gaaatagaac ctgaaaccgt gtgcctacaa caagttcgag cccgttaatg ggtgagagcg
     1801 tgccttttgt agaatgaacc ggcgagttac gatatgatgc gaggttaagt tgaagagacg
     1861 gagccgtagg gaaaccgagt cttaataggg cgatttagta tcatgttgta gacccgaaac
     1921 catgtgacct acccatgagc aggttgaagg tgaggtaaaa ctcactggag gaccgaacca
     1981 gggcacgttg aaaagtgctt ggatgacttg tgggtagcgg agaaattcca aacgaacttg
     2041 gagatagctg gttctctccg aaatagcttt agggctagcg tcgatgttaa gtctcttgga
     2101 ggtagagcac tgtttgggtg aggggtccat ctcggattac caatctcaga taaactccga
     2161 atgccaacga gatatcatcg gcagtcagac tgcgagtgct aagatccgta gtcgaaaggg
     2221 aaacagccca gaccaccagc taaggtccca aaataactgt taagtggaaa aggatgtggg
     2281 gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag agtgcgtaat
     2341 agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca gtttaccgaa
     2401 gctgtggatg acacaaaagt gtcatggtag gagagcgttc tatgtgtgaa gaaggtgtac
     2461 cgtgaggagc gctggaacgc atagaagtga gaatgccggt atgagtagcg aaagacaggt
     2521 gagaatcctg tccaccgtaa gactaaggtt tccaggggaa ggctcgtccg ccctgggtta
     2581 gtcgggacct aaggagagac cgaaaggtgt atccgatggc caacaggttg atattcctgt
     2641 actagagtat atagtgatgg agggacgcag taggctaact aaaccggacg attggaagag
     2701 tccggctaag cagtgaggtg taagatgagt caaatgctta tctttataac attgagctgt
     2761 gatggggagc gaattttagt agcgaagtta gtgatgtcac actgccaaga aaagcttcta
     2821 gcgtttaatg atactctacc cgtaccgcaa accgacacag gtagtcgagg cgagtagcct
     2881 caggtgatcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag
     2941 aaggggtgct gacttaggtc agccgcagtg aataggccca agcaactgtt tatcaaaaac
     3001 acagctctct gctaaatcgt aagatgatgt atagggggtg acgcctgccc ggtgctggaa
     3061 ggttaagagg agggtttagc gcaagcgaag atctgaattg aagccccagt aaacggcggc
     3121 cgtaactata acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg
     3181 aaaggcgtaa tgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt
     3241 gaagatgcag gttacccgcg acaggacgga aagaccccat ggagctttac tgcagtttga
     3301 tattgagtat ctgtaccaca tgtacaggat aggtaggagc cattgacttc gggacgccag
     3361 tttcgaatga ggcgttgttg ggatactacc cttgtgttat ggctactcta acccagatag
     3421 gttatcccta tcggagacag tgtctgacgg gcagtttgac tggggcggtc gcctcctaaa
     3481 gagtaacgga ggcgcccaaa ggttccctca gattggttgg aaatcaatcg cagagtgtaa
     3541 aggtataagg gagcttgact gcgagagcta caactcgagc agggacgaaa gtcgggctta
     3601 gtgatccggt ggtaccgaat ggaagggcca tcgctcaacg gataaaagct accctgggga
     3661 taacaggctt atctccccca agagttcaca tcgacgggga ggtttggcac ctcgatgtcg
     3721 gctcgtcgca tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc
     3781 ggcacgcgag ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt
     3841 aggaaatttg agaggatctg ctcctagtac gagaggacca gagtggactt accgctggtg
     3901 taccagttgt cttgccaaag gcatcgctgg gtagctatgt agggaaggga taagcgctga
     3961 aagcatctaa gtgcgaagcc cccctcaaga tgagatttcc catgatttta tatcagtaag
     4021 agccctgaga gatgatcagg tagataggtt aggagtgtaa gtgtagcgat acatgtagcg
     4081 gactaatact aatagctcga ggacttatcc aaaaagaaat attgacaacg ttacggattc
     4141 ttgttagact atagatattc aattttgagt gggttatgaa aatagcacat ttacaagtta
     4201 agtgacgata gcctaggaga tacacctgta cccatgccga acacagcagt taagccctag
     4261 aacgcctgat gtagttgggg gttgccccct gt
//
LOCUS       DAUGOH010000069         4265 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUGOH010000069 DAUGOH010000000
VERSION     DAUGOH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4265
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.069"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            168..452
                     /locus_tag="VH957_001630"
     CDS             168..452
                     /locus_tag="VH957_001630"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEQ8559516.1"
                     /translation="MRLEEIRQEINSIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QVRENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRKYQTQHLTGGDTND"
     gene            445..1707
                     /locus_tag="VH957_001631"
     CDS             445..1707
                     /locus_tag="VH957_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEQ8559517.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGVAVGVIDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILLSTWVTHLFGASAGREGVAVQIGATISHYCRRFVTSQDAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFACLLGWFKPYLSQKLPNPYIRIAFIGVLLSICLMIGHV
                     GRYSGLGTHLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGII
                     LAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            1822..2169
                     /gene="rplS"
                     /locus_tag="VH957_001632"
     CDS             1822..2169
                     /gene="rplS"
                     /locus_tag="VH957_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEQ8559518.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            2417..2488
                     /locus_tag="VH957_001633"
     tRNA            2417..2488
                     /locus_tag="VH957_001633"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2450..2452,aa:Arg,seq:cct)
     gene            complement(2533..3609)
                     /locus_tag="VH957_001634"
     CDS             complement(2533..3609)
                     /locus_tag="VH957_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ8559519.1"
                     /translation="MWIEELLNGKFKFIERYTDPLTGKYKKVSVTLDKNSNQAKNKAS
                     IIIKEKIEDRLAIRDHSEMTYGELKREYLNQWIPTVKDSTKRGYLVSDGHIATVLPDD
                     TIISKLTKRDIRQFIDNLLKNHSYHVTHKCRKRLHAILSYAIQMDYLTSNPTDNVLVP
                     KPKEEYMPEKVLYLTSNEVYDLCGRMIANNEQTLADVVLFMFLTGMRYGELACLTYDK
                     IDFENKEILINATYDFYTKEITTTKTKKSTRKISVSDNILEIINRQNKVSEFIFPNSK
                     GLPILNAYINKRLKIYGNYHTHLFRHSHISFLAEKGIPLKAIMDRVGHSDPNTTLSIY
                     SHTTVNMKALINNQTAPFMPLKII"
     gene            complement(3727..>4265)
                     /locus_tag="VH957_001635"
     CDS             complement(3727..>4265)
                     /locus_tag="VH957_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEQ8559520.1"
                     /translation="FRNNSINHYVNSYHDVPIWVIVDYMEFGDLLAFLQNLDTGLQNK
                     VATDMVSFVSDNINTSQLFTPETMIGLLKNIREVRNICAHNNRLIGFECRANSPFYNA
                     LHTKYSIRPDDSRKNVYSIFLSLQCFLSKIEYAKLHNSIRKRVNQLTNKIGQEKVNEI
                     LLYLGFPELWNQLSKLSQ"
BASE COUNT         1222 a          746 c          819 g         1478 t
ORIGIN      
        1 tagtaaaaat gtcaggggct tccttggcat ttttagcttt ttaacctaaa ataaagggaa
       61 tgtcacttca gggtaggaat tgaaaaaaca atcagcttca ccttgcttct gatcctctta
      121 ttaactataa taaaaagata atctaataca tctagaaaag gaaagttatg cgtttagaag
      181 agatacgaca agaaatcaat agtattgatc accacttggt tgccttatta gaaaagcgga
      241 tggcacttgt agagcaagta acagcttata aactagccaa tcacttgcct gtcttagatc
      301 aggtgcggga aaatcagatc ctagataggg tttcttatct cgttaaagac caagcatttg
      361 agccagctat ccatgagacg tttaaaacca ttatgtctct ttcacggaag tatcaaacgc
      421 aacacttaac aggtggtgac actaatgatt aaatcaattg caacactgcc taaaccctcc
      481 ttaaaagaag cgttaggact aataggcttg gcgcttccca taggggtcgc ggttggagtg
      541 attgatgtga tttttggtaa agggcttttg tttctttccg agtatcgcga tcaccacctt
      601 ttcttgcttc ttccttttct tgccttagca ggccttgtta tcgtttttct ttatgataag
      661 ttaggcaaag aggttcgtca agggatggga ttggtttttc aggtagggca tggtcaaaaa
      721 gatcagattc ctcctattct cattcctctt attttgttat cgacttgggt aacccactta
      781 tttggagcga gtgcgggtcg agaaggggta gccgttcaaa taggagctac catctctcat
      841 tattgtcgga gatttgtgac tagtcaagat gccgcacgac accttttgat tatggggatg
      901 gcagccggtt ttgcaggact ttttcaaacg ccaattgctg ctgtcgtatt tgcccttgag
      961 gttttgttgg taggaacgct tcgctactgc gctttattgc cttccttagt tgctgcttgc
     1021 gtggcttctt ggacctctca ttctttggga ttagagaaat ttacgattgt tcttgaagaa
     1081 acattgacca taactccctt aaccttagtt aaattaattg ggttaggtct tatttttggt
     1141 ctggtgggaa atagttttgc ctgtttactt ggctggttta aaccttacct gagtcaaaag
     1201 ctaccaaatc cttatatcag gattgctttc attggtgttt tgttatctat ctgtttgatg
     1261 attggtcacg ttggaagata tagtggtcta gggactcatt tgattgcggc agctttttct
     1321 ggccaaacta tcctaactta cgactggctt ttaaaaatga tcgtgacggt gattagctta
     1381 tctgcaggct ttcaaggtgg tgaagtgaca cctctatttg ctattggagc ttctttaggc
     1441 atcattttag ccccttactt aggtcttcct gtactgttag ttgctgcact tggttatgtc
     1501 acggtatttg gaagtgcaac aaataccttt tgggccccta tctttattgg gatagaggtc
     1561 tttggtccag agaatgccct agcatatttt gtcacctcag ctgcagccta tatggttagt
     1621 cacagacatt ccatttacag ttatcaaaaa gtagtcatga tcaatttaaa agacatgacg
     1681 gtaaatcaga tggatttaaa aaaatagctt tacaataaag aagctttttg ttagaataaa
     1741 tctcgtgtgt aatggacaca cgaaaattac ggctaatccg ctaagacaag tacttaagat
     1801 tagtaagata ggagaataaa aatgaatcca ttaatccaaa gtttgacaga aggtcaactt
     1861 cgctctgata tccctaactt ccgtcctggt gacactgttc gcgttcacgc aaaagttgtc
     1921 gaaggaactc gcgaacgtat ccagatcttt gaaggtgttg ttatttcacg taaaggtcaa
     1981 gggatctcag aaatgtacac tgttcgtaaa atctcaggtg gtatcggggt agagcgtaca
     2041 ttcccaatcc acacaccacg tgttgacaaa atcgaagtta tccgccacgg taaagtccgt
     2101 cgtgcgaaac tttactactt gcgtgcatta caaggtaaag ctgctcgtat caaagaaatt
     2161 cgtcgttagt ttgaaccgaa acgtaacgta atagaataaa aaagactaga gtctctagtc
     2221 tttttatgtc gtcgtgacaa tgtgacaatt ggtgattaac gctatgctcg taggacactt
     2281 tgaaagttcc ttagcagtta taattagtat attggaataa caaaatgaag caaaataaac
     2341 tttcagttat ctgatatttc atcttgcatt accttatttt ctaggttaaa atagaagaca
     2401 aggtgaatat aagatagacc ccttagttca atggatataa caactccctc ctaaggagta
     2461 gttgctggtt cgattccggc aggggtcatt attgttaact taaaaagcct ttatatcagg
     2521 ctttttttat tactaaatta tttttagggg cataaaaggg gcagtttgat tattaatcaa
     2581 tgctttcata tttacagttg tatgactgta aattgataat gttgtgttgg ggtctgaatg
     2641 gccaactctg tccataatcg cttttagtgg tattcctttt tcggctaaaa acgaaatgtg
     2701 tgagtgtctg aataagtgag tatgatagtt accataaatt ttcagacgct tattgatgta
     2761 tgcgtttaaa attggtaaac cttttgaatt tggaaaaata aattcactca ctttattttg
     2821 tcgattgatg atttctaaaa tgttatcaga tacggaaatt ttgcgagttg attttttagt
     2881 cttagtagtc gtaatttctt tagtgtaaaa atcgtaagtt gcgttaatca gaatttcttt
     2941 attttcaaaa tcaatcttat cataagtcag acaagcaagc tcaccatatc tcatacccgt
     3001 taaaaacatg aataaaacga catctgcgag cgtttgttca ttgttggcta tcattctacc
     3061 acagaggtca taaacttcat tagatgttaa ataaagtacc ttttcaggca tatattcctc
     3121 ttttggctta ggtactaaaa cattatctgt cggattgctt gttaaatagt ccatttggat
     3181 tgcgtaagac aaaatagcgt gtaatctttt tctgcattta tgtgtaacat ggtacgaatg
     3241 gtttttcaat aagttgtcaa taaattgtct aatgtcgcgt ttagtcaact tgctgataat
     3301 tgtatcatct ggcaacacgg ttgcgatatg accgtctgag actaaataac cacgcttggt
     3361 ggagtctttg accgttggaa tccattgatt taaatattcg cgctttaatt caccataggt
     3421 catctcagaa tgatcgcgaa tagcgagtct atcttcaatc ttttctttga taataatact
     3481 tgctttattc ttggcttgat tactattctt atcaagtgtc acagatactt ttttatattt
     3541 tccggttaat ggatctgtat aacgttcgat aaatttaaat tttccattta ataattcttc
     3601 aatccacatt tgttttatac ctcaatttct gttaaaatgg gtatagtaaa aagggctttt
     3661 taatgccgtt tactatccag aatatcctca cactcaacgt ttggcgatgg cgagtgtggg
     3721 gcttttttat tgacttaatt ttgataattg attccataat tctgggaatc ccaaatataa
     3781 taaaatctca tttacttttt cttgtccaat tttatttgtt aattgattga cccttttcct
     3841 tattgaatta tgtaattttg catattctat tttgctcaaa aaacattgaa gactaagaaa
     3901 tattgaataa acattttttc ttgagtcgtc tggcctgatt gagtatttag tgtgtaaagc
     3961 gttgtaaaaa ggtgaatttg ctctacactc gaagcctatc aatctattat tgtgagcaca
     4021 gatatttcga acttctctta tattttttaa taaccctatc attgtttctg gcgtaaaaag
     4081 ctgcgacgta ttaatattgt ctgaaacaaa gctgaccata tccgttgcca ctttattctg
     4141 taaaccagtg tctaagtttt gtaaaaaagc cagtaagtct ccaaattcca tgtagtcaac
     4201 tataacccag attggaacat cgtgataact gttgacataa tggtttattg aattatttct
     4261 aaaat
//
LOCUS       DAUGOH010000070         3922 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUGOH010000070 DAUGOH010000000
VERSION     DAUGOH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3922
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.070"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..1064)
                     /locus_tag="VH957_001636"
     CDS             complement(<1..1064)
                     /locus_tag="VH957_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8559521.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQVDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNA"
     gene            1374..1787
                     /gene="yaaA"
                     /locus_tag="VH957_001637"
     CDS             1374..1787
                     /gene="yaaA"
                     /locus_tag="VH957_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEQ8559522.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIIIIVEPSQEEKEQFAEEMAEKTRVAALVKQMNQANKK
                     TSSKHNNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            1789..2895
                     /gene="recF"
                     /locus_tag="VH957_001638"
     CDS             1789..2895
                     /gene="recF"
                     /locus_tag="VH957_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEQ8559523.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(2951..3814)
                     /locus_tag="VH957_001639"
     CDS             complement(2951..3814)
                     /locus_tag="VH957_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEQ8559524.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
BASE COUNT         1367 a          721 c          627 g         1207 t
ORIGIN      
        1 gcgttattca acaacatcga tctggtcttt ttaatcaatt gttctgagaa tcgtcccatt
       61 ttaatggcat ttaattcttg gatgattagt tgtaacgttt tagtgcgatg ttgactgtca
      121 attccagtat aaatttcaaa taaacctgta taactatcaa aacgacaccc tatactataa
      181 gcaagtcctt cttcttctct aatttttata aagagacggg aatgtgcaaa agagcctaac
      241 aacccattta aaagaactaa agcataatag tcacgttgtc caaaaactga agggaagtga
      301 taagctaatt gtaaaataga ttgatgaact gctctttttt caatagattc tttaataata
      361 ttgacagaat tttgtaaatg aaagaaattt aggtttttat ttcggttatc aagtggaaat
      421 tgatgaatta gctgaacaac gcgataatca tcaaaatctc ctaaaatgaa aatatcaacc
      481 tgatcttcat tgagcatttt atgaaattct tgatagctag tataggcagt ctcttttgca
      541 attagttctg ggctaccata ttctgacatt tgtagattct tattacaata aaacaattct
      601 tttaccttaa gagagctgta gtaaaaagaa tcctctctat ctgactcgat gtagttaatc
      661 aaattatttt tttcagtctc aaaaacttta ggctgatact gggcgatgga taataggggt
      721 gagaacaaga tatcttttaa aaactgaatc atttcatcta gtattttttc cccattgcaa
      781 gcatatctat cttgaataaa agtaatatcg atatccacaa tatgaactaa cccttttgtt
      841 aacacgttag ttgacaagct agctccataa agtcgtgcta atttttctct aaactgccta
      901 acagttggat aacactcatt agctgttgct aacatctgtg ccactaagac tctttttgct
      961 actgtttttt ggttcaaatc acctgaaaaa cgaaaggtaa tatgattggt tttaaactgt
     1021 ttggtcttaa tcagatgaag ttgtactccc tgaacaattt tcataatgtt tccttaataa
     1081 atagtgtgat ccttacgatt ataccatttt tattcaggct aggtgagtga taacttttta
     1141 aattccttac ggttaaacaa aaaaagaagc aattgacttg ctcctatgat ttactgcaaa
     1201 ataaggccag taatacctct aaaaagtttc aaccacactt tatacttaaa aatacagatt
     1261 atattatatc aaataacgtc tcactttgga atagtcaaat agctcttatt cagctattat
     1321 tatttatttc tgttttatgc tataatgact tgaatgacaa aatggagatg acaatgatat
     1381 acaaattatt tacagaattt atcaccctac aagcccttct taaagaatta ggaattatcc
     1441 aaagtggtgg cgctatcaag ggatttctcg ctgaaacaac cgttctattt aatggtgaag
     1501 atgagaaacg tcgaggcaaa aaaatcagag taggggataa gatttctcta cctgaccaag
     1561 acttaattat cattattgtt gagcctagtc aagaagaaaa agaacaattt gccgaagaaa
     1621 tggctgaaaa gacacgtgta gcggctctag tgaaacaaat gaaccaagct aacaaaaaga
     1681 cttcttctaa acataacaat cgtcaatcta ctaccaaaaa atcactaaga gcaactaaga
     1741 aaactaaagg taaaccaact gcacctgtcc gcttcccagg tatctagtat gtggattaaa
     1801 gagttagagt taaaacatta tcgcaattat gaccacctgc ttgcctcatt ttcgtcgggt
     1861 ttaaatgtct ttatcggtaa taatgctcaa ggaaaaacca attttctcga ggcaatctat
     1921 tttctatcac ttactagaag tcatcgcacg agggctgata aagaattgat tcattttgat
     1981 cactcaactg tttctcttac tggtaagatt cagcgtatta gtggtactgt tgatttagaa
     2041 atcaatctat cagataaagg acgtgtgaca aagattaatg cgctgaagca agcaaaatta
     2101 tctgattata ttggaacgat gatggttgtg ctttttgcac cagaagattt gcaactagtt
     2161 aagggagcac ctagccttcg tcgcaaattt atcgacattg accttggtca aattaagcct
     2221 gtttacttat ctgagttatc ccattataac cacgtgctta aacagcgtaa tagctattta
     2281 aaaagtgccc aacaaattga tgccgctttt ctagctgttc tagatgagca attagctggc
     2341 tatggagccc gtgtcatgga acatcgtatt gattttatca atgcgttaga gaaagaagca
     2401 aatactcatc accaagccat ctcaaatggt ttagaaagtc tctctctctc ctatcagtcg
     2461 tcagttgtct ttgacaaaaa aactaatatt taccaacaat ttttacacca acttgaaaaa
     2521 aatcatcaga aagatttctt ccgtaaaaac actagcgttg gtccacatcg cgatgactta
     2581 gccttttaca ttaacgggat gaatgctaac tttgctagtc aaggtcagca ccgcagcctt
     2641 attctttcct taaaaatggc tgaagttagt ttaatgaagg ccttgactgg agataatccc
     2701 attcttttac tagacgatgt catgagcgag ctagacaata cacgacaaac aaagttactt
     2761 gaaacagtaa ttaaagaaaa tgtccaaacc tttatcacaa caacaagttt ggatcacctg
     2821 tcacagttgc cagaaggtat ccgtattttc cacgtgacaa aaggaaccgt tcaaattgat
     2881 tctgatattc actaataaca tcaaaaaagg gttcagttaa actgagcctt tttttgatat
     2941 tatgtggcga ttaagatttg accacaccta ataaaatagc acctacgata aaacaaataa
     3001 ttcctgtgac aacccaacgc atttcttttt tggttttggt ttcgcctagg aataaaatgc
     3061 ctccaacaat cgaaatgata gcacctaatt gtgagaaact aaaggcaata gcaagtcctg
     3121 cttttgatgc agctaaaagc ataaaaatat tcccaatgcc ccaaagtaat ccaacaacgc
     3181 tatttttaat cacatactgg tcaatggaaa ttttaaatga catgaaagtt atagctccta
     3241 aaaccatacc tactgccatg ggtaaaatga ctgacaaaac ttcaaatttc atgatgttat
     3301 taaataatac agcatacatc acgtaaccaa ttgttgaata agtgagcgcc ctaaaacctt
     3361 ttgaaaaatt atgaaggtga ttgacttgtg cattagcatc atcttgttta ctagaaaagt
     3421 aaaaaccaac aatcagaagt aatagtgcta gacttcctac tacaaattgc ataggtcttg
     3481 tccattcatg aaaaacgagg acaccaatca aacttcccag aacaagttga gagccacttg
     3541 acaaaggatt ggcaacggag actcccatgt attgcatggc atgaaattga ccagtttgac
     3601 caattgacca gataaaacca cccaatattc caaaaagcca aagttgcagt gtcatctcag
     3661 gtctaacaat taaccaaaca gctaatgaaa ataataaagc cccaaaagtc attcctagag
     3721 tttgttgcga aggttttcct ccaattttgt tactaacaaa tccaatgctt ccccatgtaa
     3781 acatgggaat aagtgcataa aaaatacctt ccaaaatgtt atctccttta tagtaaatct
     3841 ttaaagatta taataattct atcataaaat ggtttcatgt aaagactaat tatagcttat
     3901 ttactaagaa aaaacaataa aa
//
LOCUS       DAUGOH010000071         3436 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUGOH010000071 DAUGOH010000000
VERSION     DAUGOH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3436
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.071"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            293..754
                     /locus_tag="VH957_001640"
                     /pseudo
     CDS             293..754
                     /locus_tag="VH957_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            824..2656
                     /gene="lepA"
                     /locus_tag="VH957_001641"
     CDS             824..2656
                     /gene="lepA"
                     /locus_tag="VH957_001641"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEQ8559525.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK"
     gene            2832..>3436
                     /locus_tag="VH957_001642"
     CDS             2832..>3436
                     /locus_tag="VH957_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEQ8559526.1"
                     /translation="MNKTKQNKTKQNKTKHSLLCRYGLTSAAALLLTFGGASAVKADN
                     QQLELAKKKNDLMTELHSNLEQMKSGTLPSSNGDVEESTVKKILKYLEERDRLEDQWR
                     EKLFEGMQNKLFDGQDGAKGEPGAKGEPGPKGEPGAKGEPGAKGDRGETGDKGEQGPA
                     GKDGDRGPVGPAGKDGQDGKDGLPGKDGKDGQDGKDGLPGK"
BASE COUNT         1024 a          630 c          827 g          955 t
ORIGIN      
        1 tatttgggat gagttttaga gctatgctgt tttgaatggt cccaaaacta tcactaactc
       61 cctattgcgt ggggaactgt tttagagcta tgctgttttg aatggtccca aaacgactca
      121 tcccaactac cgtaagccct aaaggtttta gagctatgct gtcttgaatg gtctccattc
      181 aacattgccg atgataactt gagaaagagg gttaatacca gcactcggat accttcctat
      241 tctttctgtt aaagcgtttt catgttataa taggcaaaag aacagtagag tgatggaaca
      301 aacatttttt atgattaagc cagatggggt taagcaaggg gggttagttg gagaggtttt
      361 gcggtggatt gaacgcctaa gacttacgtt taagtgattc gagctaagac aagctagttc
      421 gaaatacttg gctaagcacg acgaggcctt ggtgataaac cttttgatcc taaacttaaa
      481 gcttacatga caagtggtcc tgttttaatt aggacacttc ttggggacta aggtggtttt
      541 gtctttttga accatgatga gagtaaccaa tcctacggat gctctttgcg gaaccattcg
      601 tgggaatttt gctcaggctc ctcgtgatga tggaggtgtt tttaacatgg cgtatgggcc
      661 tcattcaaga gactctgcta ggcgtgagat tttcctttgg tctcatcaaa gtaatctcgg
      721 tagctccgct attctctcac aagataatcc gtaagaaaag ataggcaaag gcctaccttt
      781 tttgttataa tagaaggaaa gactaaatgt ataggaaaat agaatgaaca gtcaagattt
      841 aaaaaaacgt caggagaaga ttcgtaattt ctccattatt gcacatattg accatggcaa
      901 atctactctc gctgaccgca ttttggaaaa gacagagacg gtttcgtctc gtgaaatgca
      961 ggctcagtta ttggactcca tggatttgga gcgtgagcgt gggattacca tcaagttaaa
     1021 cgccattgag cttaattaca cagctaaaga tggggaaacc tacattttcc accttattga
     1081 taccccaggg catgtggact ttacttatga agtatcgcgt tcgttggcag cctgtgaggg
     1141 agcgattcta gttgtggatg cagcgcaggg cattgaagca cagacccttg ccaatgttta
     1201 cctagccctt gataatgatt tggaaatttt accggttatc aataaaattg atttgcctgc
     1261 tgctgaccct gagagagtcc gccatgaagt agaagatgtc attggacttg atgcttctga
     1321 ggctgttctg gcgtcagcca aggctggtat cgggatcgaa gagattcttg agcaaattgt
     1381 tgagaaggtt cctgctccta cgggtgatgt ggatgcgcct ttacaagcct tgatttttga
     1441 ctctgtgtat gatgcttatc gaggcgttat cctgcaagtt cggattgtga atggtattgt
     1501 caaacctggc gataaaatcc agatgatgtc taatggaaaa acctttgatg ttacagaagt
     1561 tgggattttc actcctaagg cagttggacg agatttcctt gcaacgggag atgttggtta
     1621 tgttgcggct tctatcaaaa cggtagcaga tacccgtgtg ggggatacgg tgactttagc
     1681 taataaccct gctaaggaag ccttgcatgg ctacaagcag atgaacccga tggtctttgc
     1741 agggatttat ccgattgaat ccaataaata caatgacttg cgtgaagcgc ttgaaaaatt
     1801 acaactgaac gatgccagtt tacagtttga acccgaaacg tcacaagcgc ttggctttgg
     1861 ttttcgatgc ggctttttag gcttgcttca catggatgtg attcaagaac gtttagagcg
     1921 tgaatttaac attgatttga tcatgacagc accatctgta gtctaccacg ttcacacaac
     1981 agatgaggac atgattgaag tgtctaaccc ttcagaattt ccagacccaa cacgggtggc
     2041 ttttattgaa gagccttatg ttaaagcgca aatcatggtg ccacaagagt ttgtaggggc
     2101 tgttatggaa ttatcgcagc gcaagcgtgg tgattttgtg accatggatt acattgatga
     2161 taaccgtgtc aatgtgatct accaaatccc gctggctgaa attgtctttg atttctttga
     2221 taaattgaaa tcctcaacgc gaggctatgc gagttttgat tatgacatgt cagaataccg
     2281 caggtcacaa ttggtgaaaa tggacattct tttgaacggt gataaggtcg atgcgctcag
     2341 ctttattgtt cataaagaat ttgcttatga acgcgggaaa attattgttg agaaattgaa
     2401 aaaaatcatt ccacgtcaac agtttgaagt tccgatccaa gccgctattg gtcaaaaaat
     2461 tgttgcgcgt tcagacatca aggcccttcg taaaaacgtt ttggcgaagt gttatggtgg
     2521 tgacgtgtct cgtaaacgta aattgctcga aaaacaaaag gctggtaaaa aacggatgaa
     2581 ggctattggt tctgtcgaag tcccccaaga agccttcttg agtgtccttt caatggatga
     2641 tgatgccaag aaataaccaa gcctaaccgc ttagccttca gaggagaact cttgtgggtc
     2701 tacatgacca tcttataaaa aaagaacttt acaatcattt gcacataatg ttataattct
     2761 attatagtgt tatctcatta ttaggtgagc ctacatttaa tcttattaaa gagaaagagg
     2821 aaacaaaaac tgtgaacaaa acaaaacaaa acaaaacaaa acaaaacaaa acaaaacata
     2881 gccttctttg tcgctatggc ttaacctcag cggctgctct tttgctgacc tttggaggtg
     2941 caagtgcggt taaggcggat aatcagcaac tagagttagc gaaaaaaaag aatgatttaa
     3001 tgactgaact ccatagtaat cttgaacaga tgaaaagtgg aactttacct agttctaatg
     3061 gtgatgtgga ggaaagtacg gttaaaaaaa tactaaaata tcttgaagaa agagatcgat
     3121 tagaagacca atggagagaa aaattatttg agggaatgca aaataagctt tttgatggtc
     3181 aagatggtgc caaaggtgag ccaggtgcca aaggtgagcc aggtccaaaa ggtgagccag
     3241 gtgccaaagg tgagccaggt gccaaaggtg accgcggcga aactggtgac aaaggagaac
     3301 aaggtcccgc tggaaaagat ggtgaccgtg gtccagtagg tccagctggt aaggacggcc
     3361 aagacggtaa agatggtctc ccaggtaaag acggtaagga cggccaagat ggcaaagatg
     3421 gtctcccagg taaaga
//
LOCUS       DAUGOH010000072         2577 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUGOH010000072 DAUGOH010000000
VERSION     DAUGOH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2577
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.072"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..419)
                     /locus_tag="VH957_001643"
     CDS             complement(<1..419)
                     /locus_tag="VH957_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ8559527.1"
                     /translation="MGNIPTPKANNFLEELKTIPHLIETLERDANLMSRSLVKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLEL"
     gene            complement(686..880)
                     /locus_tag="VH957_001644"
                     /pseudo
     CDS             complement(686..880)
                     /locus_tag="VH957_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
     gene            complement(846..1172)
                     /locus_tag="VH957_001645"
     CDS             complement(846..1172)
                     /locus_tag="VH957_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559528.1"
                     /translation="MIPKFRAFNKKIQKMYSIDGFKSSERKIYRCSLADDEFRSGRLE
                     TFHFVEDNLGDYILMQSTGLFDKNGVEIFEGDVVKLQYTITSDLEFFKVNQFRGGAWR
                     LFNKTS"
     gene            complement(1182..1451)
                     /locus_tag="VH957_001646"
     CDS             complement(1182..1451)
                     /locus_tag="VH957_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559529.1"
                     /translation="MKKPNRYPYSKSKFNGCIYQLHAASFKDEQYVEDLKSCGIHYQI
                     TKIGYFPDIFIKIDNLEQLQILIDKTGHDLILSKDQIWIYDDYME"
     gene            complement(1448..1630)
                     /locus_tag="VH957_001647"
     CDS             complement(1448..1630)
                     /locus_tag="VH957_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559530.1"
                     /translation="MVKHVVRVYNKGITATYAIYDKNLFQEHEFVTKIEAMQFIRKLE
                     LANDKRATEYFMREAE"
     gene            complement(1633..1857)
                     /locus_tag="VH957_001648"
     CDS             complement(1633..1857)
                     /locus_tag="VH957_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559531.1"
                     /translation="MKIDYINFFERVVPDWMRESNVKMQEVGFNTEAYWIWANQSIVT
                     ICETYGNDSLINGQFHLIWEWLESKTKESS"
     gene            complement(1854..2249)
                     /locus_tag="VH957_001649"
     CDS             complement(1854..2249)
                     /locus_tag="VH957_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEQ8559532.1"
                     /translation="MIDFFIPMKKIPTTTHQQKKVRVVNGKPQFYEPDSLKEARAMFM
                     SKFAPHAPEKKMTGPLRLTVKWLFPKIKKSVDGQYKDTKPDTDNLNKLPKDCMTALGF
                     WNDDAQVASEIIEKFWADTVGIYVKVEEL"
     gene            complement(2242..2424)
                     /locus_tag="VH957_001650"
     CDS             complement(2242..2424)
                     /locus_tag="VH957_001650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559533.1"
                     /translation="MQIEFFKNGKSDIELEYLKNEVNGFINDLREDGIKCLDIQFIFD
                     EDEIIVFVKYEGLIDD"
BASE COUNT          729 a          525 c          384 g          939 t
ORIGIN      
        1 atcaattcca gactttcctt tcctcgccta acaaacataa agtatttatt acgatttcct
       61 atgtttaagc gttctctggc tctctcatag tctccatcac agtcaagata agtcgtgagt
      121 aaaacgtgac tctcacaaat gcccatgctt tgcacaatca aattagccat ttcttgtcga
      181 cggtctttta aacgctcaat ctgatcacta taatagctaa ccatatgcag catctttatg
      241 tttttgtctt cctgtgattg tttaacccca ccagacactc gcatatcaga ccattgagga
      301 gacttaacga gcgaccgact cattaggtta gcgtctcttt caagggtctc tatgagatgt
      361 gggatagtct ttaattcttc caaaaaatta ttagcttttg gtgtcggaat gttgcccatc
      421 taactctcca ttcatgatat aatattgttg ggtatttaat catgaaggcg ttcgcatgga
      481 cgtctttttt tgtggagaaa agtcctctct ttcttttttt gtttttcgac acaggcgtac
      541 gatgtcagta ttagcgcctt gaataataac aaatgaccga taatctgcgt tagatttgtt
      601 ttggtgtaag gaggtcctcg tttctatttt ttaatttcgg tcaataccaa ccgcacgagt
      661 cgaacgtgcg tgataccgtt attggttata tccattcaat tagtggattt tcaatgtgtt
      721 ctatcccatc accaatccac tctttgacat taaattctcg ctcaatatct tgagtccttg
      781 gcataacgtt aatatcacta aaactcagca tgtcgtcttt tgtattttgc aaaaaataaa
      841 tgtttttaac ttgtcttgtt aaagagtcgc catgcaccac ctctgaattg attcacttta
      901 aaaaattcta aatcactagt aattgtatat tgtaatttca cgacgtctcc ctcaaaaatc
      961 tcaacaccgt ttttatcaaa taggcctgtg gattgcatga gaatataatc accaaggtta
     1021 tcctcgacaa aatgaaacgt ctctaagcga ccagagcgaa actcatcatc tgctaagctg
     1081 catctgtata ttttgcgttc acttgattta aagccatcaa tgctatacat tttttggatc
     1141 tttttattaa atgctctaaa ttttggtatc attattactc ctcattccat atagtcatca
     1201 taaatccaaa tttggtcttt actaagtatt aaatcgtgtc ctgttttatc tattaatatt
     1261 tgtaattgtt cgagattatc aatttttata aaaatatcag gaaaataacc aatttttgta
     1321 atttgataat gtatgccgca tgattttaaa tcttcaacat attgttcatc tttaaagctg
     1381 gctgcatgca actggtaaat acaaccatta aattttgatt tactgtacgg ataacgattt
     1441 ggtttcttca ttccgcttcc ctcataaaat attctgtcgc tcgcttatca tttgctaact
     1501 ctagttttct gataaactgc atcgcttcta tttttgttac aaactcatgc tcctgaaaca
     1561 ggtttttgtc atagatcgcg taagtcgctg taatgccttt gttgtaaact ctcacaacgt
     1621 gttttaccat ttttaactac tttcttttgt tttactttca agccactccc aaataagatg
     1681 aaattgacca ttaattaatg agtcgttacc ataagtttcg caaatcgtaa caattgactg
     1741 gttggcccat atccaataag cttcagtatt aaatccaact tcttgcattt tgacattact
     1801 ctctctcatc cagtcaggaa ccactcgttc aaaaaaatta atataatcaa ttttcataac
     1861 tcttccacct ttacgtatat tcctactgta tcagcccaga acttctcaat aatttccgaa
     1921 gcaacctgcg catcatcatt ccaaaatccc aatgcagtca tacaatcttt aggtaacttg
     1981 ttcaaattat ctgtgtcggg tttagtatct ttatattgtc cgtctactga ttttttgatt
     2041 ttcgggaata accatttgac agtgagtcgt aatggaccgg tcattttttt ctcaggagca
     2101 tggggtgcaa atttactcat aaacatggca cgagcttcct tcagcgaatc cggttcgtag
     2161 aattgtggtt taccgtttac cacacggacc ttcttttgtt ggtgtgtagt agttgggatt
     2221 ttcttcatcg ggataaagaa atcaatcatc aattaagccc tcatatttaa caaatacgat
     2281 gatctcatct tcatcaaaaa tgaattggat atctaaacat ttaataccat cttctcgcag
     2341 gtcgtttata aaaccgttaa cttcattttt taaatattcc aactcaatat cacttttacc
     2401 atttttaaaa aattcaattt gcattttttt attcctttct taatctacgc gctttgtcaa
     2461 agatgagaaa ggaatggttt tggcgaagtc taacgccaaa ccttcctttt tctttgactt
     2521 ttgacgaagg aaaaacactt ttaataactc tgataagagt tatagcgtgt ctttttc
//
LOCUS       DAUGOH010000073         2372 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUGOH010000073 DAUGOH010000000
VERSION     DAUGOH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2372
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.073"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..193
                     /locus_tag="VH957_001651"
     CDS             <1..193
                     /locus_tag="VH957_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8559534.1"
                     /translation="PGITDEEKKKIFDRFYRVDKARTRQTGGFGLGLALAQQIVMSLK
                     GNITVKDNDPKGSIFEVKL"
     gene            complement(318..566)
                     /locus_tag="VH957_001652"
     CDS             complement(318..566)
                     /locus_tag="VH957_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEQ8559535.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(620..1540)
                     /locus_tag="VH957_001653"
     CDS             complement(620..1540)
                     /locus_tag="VH957_001653"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEQ8559536.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1775..>2372
                     /locus_tag="VH957_001654"
     CDS             1775..>2372
                     /locus_tag="VH957_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8559537.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLETLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGY"
BASE COUNT          796 a          336 c          441 g          799 t
ORIGIN      
        1 tccagggata acagatgaag aaaagaaaaa gatttttgat cgtttttatc gagttgacaa
       61 agctagaaca cggcaaacag gtggatttgg cttggggttg gctttagctc agcaaatcgt
      121 gatgtcttta aaaggaaata ttacagtaaa ggataatgat cctaaaggta gtatttttga
      181 agtcaaatta taagctaaaa agggcgacca ataaggtcag cccttttaaa gttattttta
      241 actgtcaacg ctttattgta ttttttgagt ttttaccgta taaaaaaact ccagctggag
      301 ttttcattgg atatttatta gccaagtttt gcagcaaggc gtgctttatc gcggcttgct
      361 ttgtttttgt gaatcaaacc ttttgattca gctttatcga tgcttgaaga agcagcgcgg
      421 aaaagctctt cagatgggtt agcttcaaat gctttgatag cagtacgcat agctgatttt
      481 tgtgctgagt ttttttcgtt tgctttaacg ttaagttcag cgcgtttaat agctgattta
      541 atatttgcca atgttttcac ctccaaatta atctaactac attattatat agaaaatata
      601 tgcgtttggc aaccctttat cactttttga ggtaaatttc atcaatttta tgatcagcac
      661 ttttatgtaa aattaattca gcacggttac gtgtaggttc aatgaatttt tcaagatttt
      721 ctaaattaac ggttttccaa acgttgcgcg caaatgctat agcctcagat cgaggtaatt
      781 gtgcatattg ggcataataa ttatgagggt cacgttttgc taattttaaa atgcttagaa
      841 accgttcaat gtaccaggtt tcgatgtgac tgctgtctgc atcaatataa atagaaaaat
      901 caaagtaatc actcatatat aaacgattgt tttgttgatt ttgaaaaaca ttaatacctt
      961 cgacgataag gaagtcaggg ttattaaatg attgtttttg atttgggata atatcgtaaa
     1021 tatcatgaga atagacgggt gcaaaagccg tttgaccatt tttgatggaa tctagaaaat
     1081 ctaagagaag ttccatgtta taagattctg gaaatccttt acgatttaac agtccttgtt
     1141 caataagaaa ctgattagga tataaaaaac catcagtcgt taccagttcg acttgactat
     1201 tggggtgcgt tcgtgataat aaaagttgta aaagacgact agttgttgat ttaccaacag
     1261 ctactgaacc agaaattcca ataataaaag gccttaattg aatgtctttt tttagaaaaa
     1321 ggcttttaga aaaagaaaga ttttcttgcg caattttgta aacctggatc agattaatta
     1381 atggaaggta gatatcaatg acatcgttaa tactgatgtt atcatttaag ctagtaatac
     1441 ttttaagttc ctcttgtgtg aggagagctt ttgctttttg atgtaatgtt ttccaagact
     1501 ctctagaaat tttttcaaag ttgataaatt catttgacat ggtagctcct aatcatttga
     1561 cagtgcttac attataccat tttagttaaa aaataaataa tttttcgtta gtatttacac
     1621 gaaaattaat acaattaact caaaaaagcc acacattcct agtacaatta tcctgctata
     1681 ttctaacaaa tagttaaagt tcggttttta tttgtaatat agagaaaatt gttaagaaac
     1741 aagcgtcttg taaaccattt caaagtatga tagaatgaaa aagtacctta aaaagatagg
     1801 aaaaatgatg acaaagatgt attatgatga aaatccagat agcctacacg atattcatga
     1861 agtaaaagta gagctgctta atcatccctt tactttttta acggattcag gtgtcttttc
     1921 aaagaaaatg gttgatttcg gtagtcaagt attattagag acactaaatt tcaaggagaa
     1981 cgaacgtgta ctggacttag gttgcggcta tggtcctctt gggattagtc tagccaaggt
     2041 tcaaagggta gacgcaacct tagtggacat caataatcgt gctcttgatt tagctagaaa
     2101 aaatgcaact aataaccaag tggcagtaac tatttttcaa tcaaatattt atgaaaatat
     2161 tagtggccat tttgagcata ttattagtaa tcctcctatt agagcaggaa agagagtagt
     2221 tcatagcatt attgaaaaaa gcatagattt tttagtggtt aatggtgact taacgattgt
     2281 gattcaaaaa aaacaaggag ctcctagcgc taaagcaaaa atggcaacta tttttggtaa
     2341 tgttgagata ctaaggaaag ataaaggtta tt
//
LOCUS       DAUGOH010000074         1904 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUGOH010000074 DAUGOH010000000
VERSION     DAUGOH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1904
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.074"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..1770
                     /locus_tag="VH957_001655"
     CDS             <1..1770
                     /locus_tag="VH957_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8559538.1"
                     /translation="TDEGVVYKPTKGDYARTAGELIQELQKYGNDIGAVLGDYKEEAG
                     AWIRFNPLDGNGVKNDNVTDFRYALVESDSMELGKQYALFKELELPIATLVHSGKKSL
                     HAIVKVDARDYQEYRKRVDYIYQICKKNGLDIDTQNRNPSRLSRMPGIMRNGHKQFLI
                     DTNIGKTNYEEWYQWIEDLNDDLPEPETLADEWDNLPELAPELIKGVLRQGHKMLIAG
                     PSKAGKSFALIELSIALAEGQKWLGWQCEQGKVLYVNLELDRPSALHRFKDVYDAMGL
                     PPTNVANIDIWNLRGKTVPMDKLAPKLIRRSLKKNYQAVIIDPIYKVLTGDENSADQM
                     AHFTNQFDKVATELGCSVIYCHHHSKGSQGGKKSMDRASGSGVFARDPDALIDLVELE
                     LSDDLIKVRADKAANKIYQRALQERNLGYYQQYVSLDDLESNAQMRQHFEKAISDVLV
                     RKIYTDEIKQAVHAINISTGWRVEGTLREFAKFQPVNMWFSYPVHEVDTTGVLADIQL
                     EESKPNWQKAKEGRKSKKEKAEERKQKIDTAYSALFDGFTPVSLSELQEYLDSTEKTV
                     RNHLKEHGGFDIKNGIVYQKKTE"
BASE COUNT          655 a          328 c          416 g          505 t
ORIGIN      
        1 acagatgaag gggtagtcta caaaccaaca aaaggggact acgcacgtac agcaggcgaa
       61 cttatccaag agttgcaaaa atacggaaac gacatcggtg ctgtgcttgg cgactacaaa
      121 gaagaagctg gggcatggat acgatttaac cctttagatg gcaatggcgt caagaacgac
      181 aatgtaacag actttaggta tgccttggtt gaatccgata gcatggaact tggtaaacag
      241 tatgctttat ttaaagaact agaattgcca atagcgacat tggtccatag cggtaaaaaa
      301 tcattacacg ctattgtcaa agtagatgct agagattatc aggagtaccg caaacgggtt
      361 gattacatct atcaaatctg taagaaaaac ggtcttgata ttgacacaca gaatcgtaat
      421 ccaagtcgtc tatcacgaat gccaggtatt atgcgaaacg gtcacaagca atttttgatt
      481 gatacaaata ttggtaaaac caattatgaa gaatggtatc aatggattga agatttaaat
      541 gatgatttac cagagcctga aacgctagct gatgaatggg ataatttgcc agagcttgct
      601 cctgaattaa ttaaaggagt gttacgccag ggacataaaa tgctaattgc aggaccatcg
      661 aaagctggca agtcatttgc tttgattgag ttatctatcg ctttagccga gggacagaaa
      721 tggttaggct ggcaatgtga acaaggaaaa gttttatatg tcaatttgga gctcgataga
      781 ccatcagctt tgcaccgctt taaagatgtt tatgatgcaa tgggattacc tcctactaat
      841 gtggcaaata ttgacatttg gaacctccgt gggaaaacag taccaatgga taagttagca
      901 cctaaactta tcagacgctc acttaagaaa aattaccaag cggttattat cgaccctatt
      961 tataaagttc tcactggtga tgaaaacagt gctgatcaga tggcccattt tacaaatcaa
     1021 tttgataagg tagccacgga acttggatgt agcgtaattt actgccacca ccattctaaa
     1081 ggaagtcaag gtggtaaaaa gtccatggac agggcaagtg gttctggagt atttgctcgt
     1141 gatcctgatg cattgattga tttagtagag cttgagctta gcgatgattt gattaaggtt
     1201 cgtgctgata aggctgccaa taaaatctat caacgtgctt tgcaagagcg aaatctaggc
     1261 tactaccaac aatatgttag ccttgacgat ttggaaagta atgcacagat gagacaacac
     1321 tttgaaaaag cgattagtga tgtcctagta cgtaaaattt acacagacga aatcaagcag
     1381 gctgtccacg ctatcaacat tagcacaggc tggcgagttg aaggaacttt acgtgaattt
     1441 gctaaatttc agccggtcaa catgtggttt agttatccag tgcacgaagt tgatacaact
     1501 ggtgtgttgg cagatataca actggaggaa agtaagccga actggcagaa agctaaggaa
     1561 ggtagaaagt caaaaaaaga aaaggcagag gaacgtaagc aaaaaataga tacagcctac
     1621 agtgctctat ttgatggctt cacacccgtt tcattatcag agttgcaaga gtatctggat
     1681 tctaccgaaa aaacagttcg aaatcatctc aaagagcatg gtggttttga tattaaaaac
     1741 ggaattgtct atcagaaaaa aacagaatag ggaaagaaaa taacagaaaa ttttccctgt
     1801 aaaaaacaga gaattttatg ttattttccc ttcctaaatc ctgtaaaaaa cataaatttt
     1861 ccctttttct aaatcctgta aaaaacagag aattttatgt tatt
//
LOCUS       DAUGOH010000075         1813 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUGOH010000075 DAUGOH010000000
VERSION     DAUGOH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1813
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.075"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            151..885
                     /locus_tag="VH957_001656"
     CDS             151..885
                     /locus_tag="VH957_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ8559539.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSEFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIKGLDYKWSENTSIKEALNE"
     gene            878..>1813
                     /locus_tag="VH957_001657"
     CDS             878..>1813
                     /locus_tag="VH957_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ8559540.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEI"
BASE COUNT          683 a          218 c          362 g          550 t
ORIGIN      
        1 tcgattataa aacaatcatt catgaaatcc atgaacattt tatagactta atttttagtt
       61 tagaagtaca tgaaaaagaa atagacaaaa aggcagaagt agtgaggaag tcttatctga
      121 cactaaatga gtatattaat ggaggctaaa atgaatttga gtatatttgg tttaaagaat
      181 attccttatt tgaaagaagg ggatagtata gaaaagctta ttgaagaaag cattaaaact
      241 tcagaatttt ttatcgaaga caatgatgtg ctttgcatag cttctaaagt tgtatctatc
      301 gcagaaggcc aggtgatgtc tttaaacgag atacaagtga gtgatgtagc aaaagaaatc
      361 cacaggaata ttcctcgtaa agatcctaga ataattgaaa ttatgctaaa tttagtcaat
      421 agagatctgt cacgtttaga tatcaaaaaa aattacattg gttgtcgctt ggaaaatggt
      481 ttaaagttga caagtggtgg aatcgataga aaatcagtag atgaagtatt tcttttacct
      541 aataatccgg atgcttctgc aaaaagaatt tcggaatatc ttaaaaaatc acttggaaaa
      601 aatgttgcag ttgttataac agatagtgat ggtagagagg ataaaagagg tgctactcaa
      661 gtagcaattg gtatttatgg tattcatcct ttgagaaaaa cagaagtaat agattcacaa
      721 ggagagacaa taaaattcca agaagagact ttgtgtgata tgattgcagc ttgtgctggc
      781 ttagtaatgg ggcaacgtgg aactggaatt ccagctgtcc tcattaaggg cttggattat
      841 aaatggtctg aaaatactag tattaaggaa gcgttaaatg agtagaaatc aggactgtaa
      901 gaatattcta atcattggtt ttggaaaaat tgggaaaatt aaagcgtaca agtggctatc
      961 acgcggatat gaggtatatg tcaaagattt gaaattctcc agcatgaaat accttaatac
     1021 aaatagtgat gtgttggatg atttatcacg acaatatttt actattgaga tttgtactcc
     1081 gacaaatcac caccttacgc tattgaaaac cgttataaca aggtatgtct attcttatat
     1141 tagcattgaa aaaccactgt gtaacaggtt agaagattta gaagaaatga agtcgctagt
     1201 agaaagtcac ccacatctag caaaaaaaat ttttgccagt gaacaatact tcttttcgaa
     1261 aattttggaa aaactgttac aagtagattg tttctctcta gataaaatca aggaaataac
     1321 agttaatttt tctaaagata ggattgagga taacgagaat gggagatttt tagataaaga
     1381 gatattgggc tatggaatag agattcctca tatcattgct gtcatttctt atttaggaat
     1441 ttcattagaa gaattcaaaa aaggaatctt tgtgaatgct atttatataa aagacttaga
     1501 gaaacatgat tattcaatag aaatattatc ttgtattaat caaacagtga ttaaaattat
     1561 tagtaatttg ggaagttttg caataagaga gggcaagatt gaaggaggtg atgctaaaac
     1621 agtaagaaga gttaccattg atgacaaaac aatactattt gatccacatc ctaaactcga
     1681 gaggtataag agtgaattgg tgactgggac aaatacgttt caaatacacg atgatatgat
     1741 ggacacgtat atcagtttgt tagaaggaaa tgctattcct gaagattgct atatcaataa
     1801 tgcaattgag ata
//
LOCUS       DAUGOH010000076         1767 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUGOH010000076 DAUGOH010000000
VERSION     DAUGOH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1767
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.076"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..1022)
                     /locus_tag="VH957_001658"
     CDS             complement(<1..1022)
                     /locus_tag="VH957_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8559541.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVNRSLRMDKALLK
                     QLITIL"
     gene            complement(1015..1689)
                     /locus_tag="VH957_001659"
     CDS             complement(1015..1689)
                     /locus_tag="VH957_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8559542.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
BASE COUNT          604 a          342 c          218 g          603 t
ORIGIN      
        1 aataaaatcg ttattaattg ttttagtaaa gccttatcca ttcttaacga tctattgact
       61 tggttctgaa aataaaatat ttttccatat tctttagcaa ctagttcata attctcaaaa
      121 atagcattaa aaaaatctgt atctaaatga gtccactgtg gattaatgcc atcatctcgt
      181 cttgctaaat ttaataaatt agttgttaag atgcgcatgt tgcgaacctc gtctaaacta
      241 gaagcgagat gctcactatt ttctaatatc gtttcgttgg gcttacgaaa aagcgattcc
      301 agacgattct gtaagaccgc caaaggggtc cttagttcat gactagcatt ttcaacaaac
      361 attttttgtt tttcatagct ttctaaaata ggttttctgc tccacttggc taaataaata
      421 cttgctaaaa tagaaattag ccaaaaaaca ctcataacta taataataat gcgctcataa
      481 cgttcattag cgcggtctaa ttgttccaca tttactactg ccatcatata ggcaactgca
      541 ggataatttt tgatatgaac ccttacagtt atcgtatggt atttttcttc ttgtccataa
      601 aaattcatta aactggtggt ttcaatactc cccaaccggc gtttatctaa atgaaaattt
      661 tgatagttag aaaacgcatc aaaagcattt aaaattgttc cattagcact aaacaaaatg
      721 atatctgtat tagctgcagg cgttcctaat aacttagaac tatctgaatc aggcagcgcc
      781 ttaataatgt tattttcagt atcaaagtaa aaagaagata ttctagccat cgtacgatta
      841 gcatagctac ttgcattatt actaacagaa actaaactac tatcaactga cgaataaacg
      901 ccaaaccgca taatctgtaa gataataata gtcataatga caaaaatacc tgtaaaaacc
      961 gcaaaaaaat gaaaaaagtg gttatagtta tctgataaaa tctctttttt taatttattc
     1021 attgtttttt agaatatacc ctacgcttct taaagtttga agcctgttaa caaaacgggt
     1081 accttttaat tttttcctta ttttagaaat gtaaacttca acaaccgaaa tcgtagtatc
     1141 actatcgaat ccccataaac gatcaaaaat ttgtgtcttt ggtaaaataa cgttttgatt
     1201 ttgcaaaaga tacaccaaca aatcaaattc tttgccaagt aattcaacta ctttcccttc
     1261 aaccttcacc tcttttcgag ctaagtcgac cactaaattg ccaaaactaa tatttttatc
     1321 tgcaaatttc cctgttcttt ttaacagtgc ttgaattcgc atttttaact cttctaaata
     1381 gaacggcttt gtcagataat catcagcacc taattcaaat ccgtgacctt tatcatctaa
     1441 accctcttta gctgtcatga tcaacacagg aattttaata tctttttctc gcaattcttt
     1501 taagacttga aagccatttt tctccggcaa cataaggtct aacaaaatca aatcataaat
     1561 accactttct gcttcgtata aaccttcatc gccatcaaaa acttgcatga cgtctgcaaa
     1621 atcatctaaa aaatcaaaaa tggaatttga taagctcaag tcatcttcta ctaataatat
     1681 ctttatcatg tctctacctc aattgttctt aaataaagta actatcactt catttaactt
     1741 agtctcattt ctgataataa tttctaa
//
LOCUS       DAUGOH010000077         1674 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUGOH010000077 DAUGOH010000000
VERSION     DAUGOH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1674
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.077"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            177..>1674
                     /locus_tag="VH957_001660"
     CDS             177..>1674
                     /locus_tag="VH957_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEQ8559543.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDTFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQRLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLS"
BASE COUNT          480 a          266 c          293 g          635 t
ORIGIN      
        1 atcatttttc aacttacttt gtttatgcac tgtcactttg ctatgtgtaa tacaaagtca
       61 tgttatttat ctcatactaa aaaaataatg gataatagct atgttagact agtgacatga
      121 agaaatattg cttttattga atcgttagag aatatgatat ttcaaggaga aaaatagtga
      181 tcgagttaaa cgatgaattc atccgaaaag agacgataga actggccaac gatggcccac
      241 gagtacacac cactcaatat gaaactaaag tacctcggct tcataaatgc tatctgcttt
      301 tctttagcat tattatcagt tctttaacaa ttgcagtacc ttttttaaca gatgcagcca
      361 atggtcttca gtcccaaaac ttatatatag gaatgatgtt aacgaagggg caacttccct
      421 atagtgatac ttttacaaca ggagggctct tttactttgt catcattgca ttaagttatt
      481 atttgggatc gacactttgg ctagtctttg ttcaggtgtt ttgtttttac ttatctggtt
      541 tatatcttta taaactcatt aattatatga caggctttca aaaagtggct ttaacttttt
      601 caattagcta ctatttgttg tctgttagtc ttggttttgg gggattgtat cctactcaac
      661 tggctatgcc atttatatta atatcggctt ggtttttaac taagtatttt gcctgtttag
      721 tgaaagatga ggcatttatt ctttttggct ttgtaggtgc tcttgcaatg ctaattgacc
      781 caagtaccct tatcttttgg tcttttgctt gtgtgacagt tttttcttat aatataagcc
      841 aaaagcatct tgcaagaggt ttttatcaac tgctagcttc gatttttgga atgattttag
      901 ttttttatac agcaggatat ttcattttga acttacaagt gctaaatcct tatttatcac
      961 aaacgatgat ttatcctttt acttttttta aatcaggaaa cttatcgttg ctttttggac
     1021 tggctattca gttgttcttc gctttggggc ttggtctttt gacggggatg gagaatgtca
     1081 ttaggcgatt taaaaacaat tctgataggg tcgtcaagtg gctatttgtc atggtcattc
     1141 tagaatctat acttgtggct atattttcac aagactatcg cccctatcat cttttacctc
     1201 ttttaccttt tggattaatt ttgactgcta ttcctgttgg ctatcagtat ggtataggat
     1261 taggtcagag tagtcatcgc agacgtcatg gtaaaaatgg tgttggtcga gtaatgatga
     1321 tttatcttaa gagacacttt tatttgccaa ttttaattgt agggacaata ctaatctgtt
     1381 ctacttattg tttcattagt agtattcctc ttaatcagga gcgtgatcat attgctagtt
     1441 atttagaaca gagactaaat aaaactcaat ctatttatgt ttgggatgat acttctaaaa
     1501 tttatttgga cagtaaagct aaatctgttt ctcaatttag ttctcctgac atcaatacgc
     1561 aaaaagcgag tcatcgaaaa atattagaag atgaactatt agaaaataag gctgcttata
     1621 tcgttgttaa ccgctataaa aacctgccta aaatcattca aaaagtatta tcta
//
LOCUS       DAUGOH010000078         1640 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUGOH010000078 DAUGOH010000000
VERSION     DAUGOH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1640
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.078"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            41..712
                     /gene="sdaAB"
                     /locus_tag="VH957_001661"
     CDS             41..712
                     /gene="sdaAB"
                     /locus_tag="VH957_001661"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEQ8559544.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            724..1596
                     /gene="sdaAA"
                     /locus_tag="VH957_001662"
     CDS             724..1596
                     /gene="sdaAA"
                     /locus_tag="VH957_001662"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEQ8559545.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKKQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIESQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
BASE COUNT          537 a          291 c          332 g          480 t
ORIGIN      
        1 tttgttataa taaacataga aataaaaaac ggagttgcct atgaatacac aaaaatttca
       61 atcagttttt gacatcattg ggccagtaat gattggtcca tcaagtagtc acacagctgg
      121 tgccgtcaga attggtaagg tagtccattc catctttgga gatattcctg atgaagtgac
      181 gtttcacctt tataattcat ttgctaaaac ctacagagga catggtactg ataaggctct
      241 tgttgcagga attatgggta tggatactga taatcctgat attaaaaatt ctctagaaat
      301 tgctcatcaa aaagggataa aaatctattg ggatatctta aaagatagta atgctcccca
      361 tcccaatact gttaaaatca gtgtcaaaaa agctgacaaa acacttagtg ttactggtgt
      421 ttcaattgga ggaggaaaca ttcaagtaac agaactaaat ggtttttctg tctcgttatc
      481 catgaatact cctactatag ttactgtaca caaagatatt cccggaatga tcgcaaaggt
      541 aactgatatc ctatcttcca ataatattaa tatcgccaca atgaatgtta cacgtgaatc
      601 tgctggtgaa aaagctacta tgattataga agtcgattct agagagtgcc aagaagcagc
      661 caaccaaatt gcaaaaattc ctcatattta taatgtcaac ttctttgact agaaaggaaa
      721 gctatgtttt atactattga agaacttgtc aaacaagctg accaacaatt taatggaaat
      781 attgctgaac tcatgattgc cacggaagtg gagatgtctg gaagaaatcg agaagatatt
      841 atcaaaatca tgtcacgcaa tttacaagtt atgaaagcag ctgtaacaga aggactaacc
      901 tcaaccaaat ctatcagtgg tttgacaggg ggcgatgcgg tcaaaatgga taactacatt
      961 aaaaaaggga acagcctttc tgatactact attcttaatg ctgttagaaa tgctatagct
     1021 gtaaacgaat taaatgctaa aatgggactt gtctgtgcaa cacccactgc aggaagtgca
     1081 ggatgcttac cagcagtgct cgcaacagct attgaaaaac ttgacttatc agaaaaaaaa
     1141 caattagagt ttttatttac tgcaggagct tttggtcttg ttattggaaa taacgcctct
     1201 atttctggtg cagaaggtgg atgccaagca gaagttggtt ctgcagctgc tatgagtgca
     1261 gctgctcttg ttaaagcagc tggtggaaca tctcatcaag ctagtcaagc tattgcgttt
     1321 gttatcaaaa atttattagg acttgtctgt gatcctgttg ccggcctagt agaagtgcct
     1381 tgtgtcaaac gcaatgccct aggagcaagt ttcgcccttg tcgcagctga tatggcttta
     1441 gctgatattg aatctcaaat tcctgttgac gaagttattg atgctatgta tcaagtcggc
     1501 tctgccatgc caactgcttt ccgtgaaaca gcagaaggtg gtttagccgc tactccaact
     1561 ggacgacgtt acagcgtaga aatatttggc gaataaatag atagttagaa aaattcttag
     1621 aaatatttga aagcgtttta
//
LOCUS       DAUGOH010000079         1557 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUGOH010000079 DAUGOH010000000
VERSION     DAUGOH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.079"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            59..592
                     /locus_tag="VH957_001663"
     CDS             59..592
                     /locus_tag="VH957_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8559546.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFRTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            complement(746..1357)
                     /gene="rpsD"
                     /locus_tag="VH957_001664"
     CDS             complement(746..1357)
                     /gene="rpsD"
                     /locus_tag="VH957_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEQ8559547.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
BASE COUNT          524 a          275 c          287 g          471 t
ORIGIN      
        1 agaaaaaaat tcacttttgg acattatgtc taaaagtgtt caaaaggaga gatggtagat
       61 ggtcaaccgt aaagaaaata cgaagcaagc aattttaaaa gcaatggtta tgttactaaa
      121 aaccgaaagt tttgacgata ttaccacagt taaattatct aaaagagctg gaattagtcg
      181 ctctagtttt tacacacact ataaagataa atatgaaatg attgactatt atcagcaaac
      241 cttttttcac aaattagaat atatttttga gaaaaaatat caaaataaag aacaagcctt
      301 ccttgaagta tttgaatttc tccaaagaga acagcttctc tcttcccttt tgtctgctaa
      361 cggtactaaa gaaatacagg cctttatcat caataaagtt cgcctactca tcactactga
      421 tttacaggac aagttccgta ccgaagagtt atctcaaacg gaaaaagaat accaaagtat
      481 ctacttagcc catgcttttt ttggtgtctg tcaaagttgg attgctaaag gtaaaaaaga
      541 atcacctcaa gaaatgacac aattcgttct caaaatgctt acgagtacct aaatagtaac
      601 ccttacgaaa gtatcatttt acaagtcatc agccttagtg ataacttttt tagaagccat
      661 agtaaaatga agggatcaga atagatttgt tatgagatac aaaaaaagcc tattaaatag
      721 gctttttgta agtttaatct taaaattaaa gcattttgtt atagaattca acgacaagtg
      781 cttcattgat ttctgggtta atttcatcgc gttctggaag gcgagtcaat gaaccttcaa
      841 gtttttcagc atcaaatgat acgaaagctg gacgcccaag agtagcttca acagcttcaa
      901 ggattgcagg tactttcatt gatttttcgc gaactgaaat cacttgacct ggatcaacgc
      961 ggtatgaagg gatatcaacg cgtttaccgt caacaaggat gtgaccgtgg ttaacgaatt
     1021 gacgtgcttg acgacgagta gttgctaaac ctagacggta aacaacgttg tcaagacgac
     1081 gttctaaaag aaccataaag ttgaaaccaa gagttccttc tttgattttt gtagcttgaa
     1141 cgaacaagtt acggaattgt ttttcaccta aaccgtatga gaaacgaagt ttttgtttct
     1201 cagctaactg caaaccatat tctgagagtt tgctacggtt gtttggaccg tgttgaccag
     1261 gaacgtagtt acgacgtgcc aattctttac ctgtgcctgt aagtgataaa ccaaggcgac
     1321 gtgattgttt ccatgatgga ccagtataac gtgacatatt acatgtcctc ctctaaattt
     1381 tttgaggaaa taacggttta aaaaatcctg attcgtgcag ggggttttcg cctaaacagc
     1441 aaaggttact tgaatagata accacctgtt gacgagcttc atatttttct gctgttattt
     1501 cgcacaaaga acagtttacc ataagaaagt tgttttgtaa agtcagtcta tctatca
//
LOCUS       DAUGOH010000080         1443 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUGOH010000080 DAUGOH010000000
VERSION     DAUGOH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.080"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            214..1335
                     /gene="mnmA"
                     /locus_tag="VH957_001665"
     CDS             214..1335
                     /gene="mnmA"
                     /locus_tag="VH957_001665"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEQ8559548.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDEDGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          446 a          237 c          316 g          444 t
ORIGIN      
        1 taataaaaaa ttattgagca ataaaatgat tggcattcca cgcagtaatt gttataataa
       61 ggtttgcgct gatggcgctt caaaatcgac cttcaaatcg acttttgaaa acgacgacct
      121 tcaatcgtac gttaactgat aagaaaaaga atcataatat tcataatatg atgattatct
      181 ttttctatct tattattgat gggagaattt tttatgacag ataactcaaa gatacgtgtt
      241 gtcgttggta tgagtggtgg cgttgattca tctgtaacag ctctactttt aaaggagcaa
      301 ggttatgatg ttattggtgt cttcatgaaa aactgggacg atacagatga atttggtgtt
      361 tgcacagcta ctgaagatta caaagatgta gcagccgttg ctgatcaaat cggtattcct
      421 tactattcag tcaattttga aaaagaatat tgggacagag tatttgaata tttcttggcc
      481 gaataccgag caggtcgtac tccaaatccc gatgtcatgt gtaataagga aataaaattt
      541 aaagctttcc ttgactatgc catgacttta ggtgcagatt atgtagcaac gggacactat
      601 gctcaagtca agcgtgatga agatggtacg gttcacatgt tacgtggagc tgataatggc
      661 aaagaccaaa cctacttttt aagtcaacta tcacaggaac aactacaaaa gactttattc
      721 ccccttggtc atttgcaaaa gtcagaagtt agagaaatcg ctgagcgagc agggcttgca
      781 acggctaaaa agaaagattc aacaggtatt tgttttattg gtgaaaagaa tttcaaacag
      841 tttttgagcc agtacttacc ggcacaaaaa ggtcgcatga tgactattga tggtcgcgat
      901 atgggagaac atgccggtct tatgtattat actattggtc agcgtggtgg tctgggcatt
      961 ggtggtcagc atggtgggga taatcaacct tggtttgttg tcggtaaaga tttgtcgcaa
     1021 aatattttat acgttggtca aggtttctac catgaagccc taatgtcaaa tagtcttgac
     1081 gcctcagtca tccattttac acgtgagatg ccagaagagt tcacatttga atgtactgct
     1141 aaatttcgct atcgtcaacc cgattcacac gtggcggtgc atgttcgagg agataaggca
     1201 gaagttgttt ttgcagagcc acagcgcgcg attactcctg gtcaagctgt tgttttctat
     1261 gacggaaaag aatgccttgg tggtggtatg attgacatgg cttataaaaa tgggcagcct
     1321 tgtcagtaca tttaatgaat cttttattaa gataaaagga aagggacatt caacaattcc
     1381 tttgacatca tatgatatta tttataaaaa ccaatcatgc gttaatggat taatttatga
     1441 tat
//
LOCUS       DAUGOH010000081         1405 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUGOH010000081 DAUGOH010000000
VERSION     DAUGOH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1405
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.081"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            34..807
                     /locus_tag="VH957_001666"
     CDS             34..807
                     /locus_tag="VH957_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8559549.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
BASE COUNT          488 a          221 c          247 g          449 t
ORIGIN      
        1 agttataccc taagacactg ataggagata agaatgaaaa agaaagagcg tcatgaaaaa
       61 attctcgata tcttaaaagt tgacggtttt ataaaagtaa aagatattat cgatgaaatg
      121 aacatctcag atatgaccgc tagacgagat ctcgatacat tggcagataa aggattactt
      181 atcaggaccc atggtggtgc tcaatatttg gattattctt cagcaaagga cgaaggtcac
      241 gagaaaacac acactgaaaa gaaggtctta cagactaccg aaaaaaaaca aattgcacaa
      301 agagctaaaa acattattaa agatggcgaa actgtcttta taggtccagg gacaacatta
      361 gagcatctag ctgtcgaatt aaaaaataga aatatcaggg tcattacaaa tagccttcct
      421 gtttttttaa ttttgcaccc gagcactact attgatttga ttttaattgg tggtgaatgt
      481 cgtgaaatta ctggagcttt tgttggtgct attgccatta ataacctaga aacattgaca
      541 ttttcaaaag cttttgtcag cgcaaatgca gtttacaata attctattgc gacgtacagt
      601 gatctcgaag gagaagttca aagggttgca ttgaataatg ctgttgagaa aatccttcta
      661 gttgatagta ccaagtttga aagttatgac ttctataatt tctaccaact agatcaagtg
      721 gacttaattg tgactgataa aaatgtgaca actgatatca tagaaaagta caagaaattc
      781 tcaaaaatca taatcgctga caagtaaaag acctactcat attaaaaagc acttcagggt
      841 ttagatatat cccctgtcaa gtaaacaggg agcatatctg aaagtagtgt ttgtgttata
      901 aagaagtttc ttgttaactt attttctggt ttttttcaga cttatcagtc ttgtactgtt
      961 cctttttctg atgaataacg tggaaatagg cagacagcta tatatttcac ctctagaatg
     1021 gttgccatta ctgtcatcaa gacatgcttg ttctttatcg tatggagtga agctttcttt
     1081 tagacatcaa aatacctctt aagtagattt tggttcgtta ccatgtctac ttaagaggtg
     1141 tcttcaaagc gctttaaaac gttgatataa cagtatatta acgttttgag aattgtgaag
     1201 ctttacgagc ttttttaaga cctggttttt ggttcactcc attatttaaa gtcaaatccc
     1261 tttaaaatca atgtttctaa aatgaaaaat cactaaaaat cttatttata gacaaatact
     1321 taaacctaaa cggtatcaaa aataagtttc ggagcttatc aaataatgaa aatctgtctc
     1381 aattaccgag tcttttttat tgact
//
LOCUS       DAUGOH010000082         1398 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUGOH010000082 DAUGOH010000000
VERSION     DAUGOH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1398
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.082"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            482..763
                     /locus_tag="VH957_001667"
     CDS             482..763
                     /locus_tag="VH957_001667"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8559550.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(1246..1333)
                     /locus_tag="VH957_001668"
     tRNA            complement(1246..1333)
                     /locus_tag="VH957_001668"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1297..1299),aa:Ser,seq:gct)
BASE COUNT          478 a          294 c          165 g          461 t
ORIGIN      
        1 tttatcttca ctcagacacc ttatccttct tagaatgaat ttttagttac ttatccacag
       61 gttaataact tcttttcgcc taaaatatta tccacaatag tgacattttc tattatcagt
      121 ttatgccttt ccattttcca attagaatat tagacatctt ttttgacctt atcattatta
      181 atataagtat agtcagacct tgttttttta taagctaact atcgaaaact ggtcatctat
      241 aaatcttagt attccatcac tcaatcacaa ttcataaaga ctcgcaaact ttcacaactt
      301 ttaattctat actttctgta gtaggtaaat ccacctcaaa gattatagag tctttttaaa
      361 catatgtaaa aagttccata tgacgatcta taatgaaaag cgaccaaact atcatttcag
      421 aaagactcat atagaataat ccgattatag tataatttca ttaggaatct aaaaccttag
      481 catcacggtt ttaaattatg taaatgctgg ggacgcaaaa agcattcata atcatctctt
      541 tcattatacc agacaggtga gaaggcatgt caaagttatt accataggca tactcagtgc
      601 ccactactat gagattacta tgctttttct acaggctaaa attatcctcg attgttttca
      661 tatcccccaa cgtcttagac aagctataac tcgctttcgt atccgaatca taaatacttc
      721 tgctataaaa cctatcgcgt atagaactct caaactttac tgaaaactca tacagcatga
      781 ttcacggaag ctcatcaata atagctttat tgcccaattt ttcgtacgcc cataactaac
      841 atctagaaaa gaaaagctct tactcacaag atctctgaat ttcaataatt attcctaact
      901 ctatcaactc ttgctcttcc catttttcag acaattttta aaatttttct aaaagaaaag
      961 aaaagaaaac aagattagca atatacttaa actcaactac tctaaggcca aattagaaac
     1021 agtcaacaac cttatcaaag ccatcaagtt aaacgtttta ctcctctaca gtagtcaaag
     1081 agcctatcat tttagttatc gaaataatga acgatttaaa tattctattt agttggtttt
     1141 gaagattaca aaaaaaaaga cgataaccgt cttctttccc ctttatttat aattcatcct
     1201 ttaatatgtt tcatttaaca tattaaccaa aatatcttta caaaacggag aataagggat
     1261 tcgaaccctt gcgccagtta cccgacctaa cgatttagca aaccgtcctc ttcagcctct
     1321 tgagtaattc tccaaatata tatgggcacg agtggactcg aaccaccgac ctcacgctta
     1381 tcaggcgtgc gctctaac
//
LOCUS       DAUGOH010000083         1351 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUGOH010000083 DAUGOH010000000
VERSION     DAUGOH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.083"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..747
                     /locus_tag="VH957_001669"
     CDS             <1..747
                     /locus_tag="VH957_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ8559551.1"
                     /translation="FKEGISLYYIGEYLAECLLIEHSDTLLIHAAAVYNPLSGHSILL
                     LGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSNSGILLTYAGTSFFKIRRTAVLSDN
                     LLFKLFSKFFNRSLQFNKASWDDKISIFPKELGIRTCNFSTEISKIYYIKTDKKEKQI
                     YHSIWSDSLASLYLNELLGRHISGQVACFQSDNGKYFSTMPLINYEKNNRVREQIVKG
                     IFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            802..>1351
                     /locus_tag="VH957_001670"
     CDS             802..>1351
                     /locus_tag="VH957_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8559552.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGI"
BASE COUNT          492 a          162 c          254 g          443 t
ORIGIN      
        1 tttaaagaag gaatttcatt atactacatt ggagagtact tagctgaatg tctcttgatt
       61 gaacatagtg acaccttatt aattcatgca gcagcagttt ataatccttt atctggccat
      121 tcaattttac tattaggaga taaaggtgct ggaaaaacta cggttgcaat aaggctttgt
      181 atagaacatg ggtatcacct tattggtaat gaccaagtaa tatttggttc gaactctgga
      241 atactactaa cttatgcagg gacatctttc tttaaaataa gaaggacagc tgttttgtcg
      301 gacaatttac tgtttaaatt atttagcaaa ttttttaatc gttcattaca atttaataag
      361 gcaagttggg atgataaaat ttcaattttc ccaaaggagt tgggaatacg aacttgtaat
      421 ttttctactg aaatctcaaa aatttattat ataaagacag acaagaaaga aaagcaaatt
      481 tatcattcaa tttggagtga tagtttagca agtctatatc taaatgagct attgggaagg
      541 catatttctg gacaggttgc atgttttcaa tcagataatg gaaaatattt ttctacaatg
      601 cctttgataa attatgaaaa aaataatcgg gtacgagaac agatagtgaa gggtattttc
      661 gctaaacaaa aattatttaa aattacagca gctacgccag ctaagattgc agaagcgatt
      721 atagaaaatg ttaagaaaaa ctcatagtgt gggtgaattt ggggattaat atgaagtatt
      781 gaaaaaggag taagagtaat tatgtttgtg ataggcattc caactttaaa tgaggcagat
      841 aatatcagta gattagttaa acaaattgat gagtatgctg taaatttagg gaaagaaatt
      901 attattatta attcggatag taaaagtaca gatggaactc cgcagatttt tttagaaacc
      961 aaaacttata acaccaaagt ttcgatagta tcagaagcta aaggaaaagg ttataatgtg
     1021 agaaatattt tcgaatatgc aataaatcat gtgccgaatt tctccggttt aattttgatt
     1081 gatggagacg ttgtctcaat gaaaaaaatg tggttagaaa agatgtttat agcaattgaa
     1141 tctggaaatg atcttataat cccaaattat gctagaaaat cttttgaagg aaatgcgaca
     1201 aaccatttta tttatcccat gttagtgaaa tttttcaaac gtgatatgcc ttatcaatgc
     1261 atctctggtg attttggatt ttcaagagga ttgataaaag atttaacttt gaaatgtaat
     1321 tggcacaaat atacattagg ttacgggata g
//
LOCUS       DAUGOH010000084         1331 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.084, whole genome shotgun sequence.
ACCESSION   DAUGOH010000084 DAUGOH010000000
VERSION     DAUGOH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.084"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..>1331
                     /locus_tag="VH957_001671"
     CDS             <1..>1331
                     /locus_tag="VH957_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lantibiotic dehydratase"
                     /protein_id="HEQ8559553.1"
                     /translation="MLESYIHDLVTNDFLISDLRPPICNINSLDYLLSKLEEGTLCTD
                     LTTLKKMIEDYNDLNIGEGRDLLLQIFDKMESIYKYDNGGNYLKVDSLAEYEGDFNIL
                     SETARESIERLAEMFVKLNTNVKRRGGRKNSLEEYQLKFIGKYGENCSIPFVEVINKD
                     AGIGFPEYYKGGEGEAIELSDPIMQMFEKKYEEALLNGGHIEFYSKDLDDFQTDQSNS
                     LDSFELNFNIKIINNDVKLYLGANIGSGQAGRSFGRFYGLSETVRETIKNLNHQNNTN
                     VELSFVPKQIRLANVIQNYSDESYNTSFFTTSWDSENELRLEDIYIRYSDGKFHFTTI
                     DGKNELKFTMNNMLNSDSQSRVLRLLVDLSEFEYGLSHWSLFPWDILAQERVYIPEIL
                     FEDITIATAQWNLSVIREEIIHQKIFTGKKDIFNKFRKTYKISKDIILKYA"
BASE COUNT          505 a          144 c          257 g          425 t
ORIGIN      
        1 catgctagag tcatatatac acgacttagt tacaaatgat tttttaattt cagatttaag
       61 accaccaatt tgtaatatca attccttaga ttatctacta tctaaattag aagaaggaac
      121 actatgtact gacttaacta ctttaaagaa gatgattgaa gattacaacg atttaaatat
      181 tggggaaggt agagacttac ttttgcagat ttttgataaa atggaaagta tttataaata
      241 tgataacggt ggaaattact taaaagttga ttcattagca gagtatgaag gcgattttaa
      301 tattctatct gaaacggctc gggaaagtat agaacgactc gcagagatgt ttgtaaaatt
      361 aaatacaaat gtaaagagaa gaggggggag gaaaaattca cttgaagagt atcagttgaa
      421 atttattggc aaatatggag aaaactgctc aattcccttt gttgaagtaa taaataaaga
      481 tgcaggcata ggttttcctg aatattacaa aggaggagaa ggtgaagcaa tagagttaag
      541 cgatccaata atgcaaatgt ttgaaaagaa atatgaggaa gctctattaa atggagggca
      601 tatcgaattt tattcaaaag atttagatga ttttcaaaca gatcaaagca atagtttaga
      661 ttcgtttgaa ttaaatttta atataaaaat aataaataat gatgtgaagt tatatttagg
      721 agctaatatc ggttctggac aagcaggtag aagctttgga agattctatg gattaagcga
      781 aacagtaaga gaaacaatta agaatttaaa ccatcaaaat aatacgaatg tagagttgtc
      841 atttgttcct aaacagataa gacttgcgaa tgtaattcaa aattatagtg atgagtctta
      901 taatacttca ttttttacca catcatggga ttcagagaac gaactgcgat tggaggatat
      961 ttatataaga tatagtgatg gtaagtttca ttttacaact atcgatggga aaaatgagtt
     1021 gaaatttacc atgaataata tgctaaattc cgatagccaa agcagggttt tgagattgtt
     1081 ggttgattta tctgagtttg agtacggttt atcgcattgg tcattatttc cttgggatat
     1141 tttggctcag gaaagagtat atattcctga aattttattt gaagacatta cgattgccac
     1201 tgctcagtgg aatttatcag taattagaga agagattata catcaaaaaa tatttactgg
     1261 taaaaaagat atattcaata agtttagaaa gacttataag atatctaaag atattatttt
     1321 gaaatatgca g
//
LOCUS       DAUGOH010000085         1274 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUGOH010000085 DAUGOH010000000
VERSION     DAUGOH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1274
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.085"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            75..1208
                     /locus_tag="VH957_001672"
     CDS             75..1208
                     /locus_tag="VH957_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="HEQ8559554.1"
                     /translation="MIDFIISIDDCAVELDSRQSWKIGYPLSTILFLVFVCQLAGIET
                     WKEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQSLTSLD
                     AVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLR
                     TIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEE
                     LQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQL
                     SQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNLI
                     RKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG"
BASE COUNT          401 a          196 c          280 g          397 t
ORIGIN      
        1 cttttgtttt cagaaaacta gattcataat gacaaaatca atcaaagtag tacactatag
       61 atgaggtgac tacgatgatt gattttatta tttctattga tgattgcgca gttgaattgg
      121 atagtcgtca atcttggaaa attggctacc ccttatcaac cattctattt cttgtcttcg
      181 tttgtcagtt agctggcatt gaaacctgga aggagatgga agattttatt gaaatgaatg
      241 aaccattgtt tgcgacctac gttgatttga gtgaaggttg tccgtctcat gataccttag
      301 agcgtgtgat tagtcttgtt aattcagacc gtttaaaaga gcttaaagtt caatttgagc
      361 aatcattgac aagcttagat gccgttcatc aactgatttc agtggacggt aaaacgattc
      421 gaggcaatcg aggtaaaaat cagaagcctg ttcatattgt aacggcttat gatgggggtc
      481 atcatcttag tttgggacag gtagcggttg aggagaaaag taatgaaatt gttgccattc
      541 ctcagttatt gcggacaatt gatatccgta aaagcattgt aacgatagac gcaatgggca
      601 cgcagacggc tatcgttgat acgattatta aaggtaaagc agactattgc ttagccgtca
      661 aaggaaatca agaaacactt tatgatgata ttgctcttta ttttagtgat gtcaacttat
      721 tggaagaact ccaagaaaat gcacagtatt atcagactgt tgaaaaatct aggggacaga
      781 ttgaagttag agaatactgg gtgtcttccg atatcaaatg gttgtgtcaa aaccatccca
      841 aatggcataa gttacgtggt attgggatga ctcgtaacac gattgataag gatggtcagc
      901 tgagtcaaga gaatcgttat tttatcttta gctttaagcc ggatgtcctc acatttgcca
      961 attgtgtacg aggtcattgg cagatagaga gtatgcactg gttattggat gttgtttatc
     1021 atgaagatca tcatcagaca ttggataaaa gagccgcatt taacctaaat cttatccgaa
     1081 aaatgtgctt atattttctc aaagtgatgg tatttcctaa aaaagacctc agttatcgtc
     1141 gcaaacaacg gtatatttct gtccatttgg aagattattt agtccaatta tttggagaaa
     1201 gaggctaagc agatgattga tttaaaaagg aatcttttca aaattgatgt ccgggcacaa
     1261 aaggatgaag agaa
//
LOCUS       DAUGOH010000086         1223 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUGOH010000086 DAUGOH010000000
VERSION     DAUGOH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1223
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.086"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            21..>1223
                     /locus_tag="VH957_001673"
     CDS             21..>1223
                     /locus_tag="VH957_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8559555.1"
                     /translation="MNNRKKNIQYLVYSKVIYRIGDVMFDFANNTFLAGLNPASLSLV
                     AVYQSLESVIGVLFNLFGGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAI
                     VLTNVILAFMSAFSGPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYK
                     LLGIHGVLLLDGLSFLIAALLISFILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHK
                     SIFIITVLSALVNFFLAAYNLLLPYSNQMFGEISTGLYGTFLTAEAIGGFIGAILSGF
                     VNKELSSMRLILFLSLSGLMLMLAPPFYIMFHNAIILALSPALFSLFLSIFNIQFFSL
                     VQKDVDNDFLGRVFGIIFTITILFMPIGTGFFSVALNPNNSFNLFIIGSCITILSLVF
                     RILFKKYNI"
BASE COUNT          371 a          166 c          198 g          488 t
ORIGIN      
        1 aaattttaaa ggtctttaaa atgaacaata ggaaaaaaaa tattcaatat ttagtgtata
       61 gtaaagttat atatcgaatt ggcgatgtta tgtttgattt tgctaacaat acttttcttg
      121 ctgggcttaa tccagcgtct ctatcattag ttgcagtata tcagtctcta gaaagtgtta
      181 taggtgttct atttaattta tttggtggag tcattgcaga cagtttcaag cggaaaaaaa
      241 ttattattac tacaaatatc ttatgtggca cagcttgctt agtactctcg ttcctaacaa
      301 aagagcaatg gttggtttat gccattgtac taactaatgt tatcttggca tttatgagtg
      361 ctttttctgg tccatcctat aaagcattta caaaagaaat tgttaaaaaa gatagtatat
      421 cacaacttaa ttcattgcta gagacaacaa gtactgtaat caaagtaaca gttcctatgg
      481 tagcaatttt cttatataag ctacttggta tacacggtgt attactattg gatggactat
      541 catttctaat agctgcttta ctaatttcct ttattttacc tgttaatgac gaagtggtga
      601 taaaggagaa ggtgacaatc agagaaatat ttaacgattt aaaaatagga tttaaatatg
      661 tttacagcca taagtccatc tttattatta ccgttctttc tgcacttgtt aatttttttc
      721 tagccgctta taatttattg ttgccctata gtaatcaaat gtttggagaa atttcaactg
      781 gactttatgg cactttttta acagcagaag caattggtgg atttattggg gcaatattaa
      841 gtggttttgt gaataaagaa ttatcaagta tgagattgat attgtttcta tctttatcag
      901 gactgatgtt aatgttagct cccccatttt atattatgtt tcataatgca attattttag
      961 ctttgtcacc agctttattc agtttatttc tttccatctt taatattcaa tttttttctc
     1021 ttgtccagaa agatgttgat aacgattttt tagggagagt gtttggtatt atctttacaa
     1081 taactattct ttttatgcct attgggactg gctttttctc ggtggcatta aatcctaaca
     1141 atagctttaa tctttttatt attggttcgt gcattactat attgtcatta gtatttagaa
     1201 tattatttaa aaagtataat att
//
LOCUS       DAUGOH010000087         1143 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUGOH010000087 DAUGOH010000000
VERSION     DAUGOH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.087"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            3..1028
                     /locus_tag="VH957_001674"
     CDS             3..1028
                     /locus_tag="VH957_001674"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEQ8559556.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPTANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWLDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSN
                     GNLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQ
                     DSWNQTN"
BASE COUNT          397 a          189 c          224 g          333 t
ORIGIN      
        1 ttatgagaaa aagatgctat tcaacttcag ctgcagtatt ggcagcagtg actttatttg
       61 ctctatcggt agatcgtggt gttatagcag atagtttttc tgctaatcaa gagattagat
      121 attcggaagt aacaccttat cacgttactt ctgtttggac caaaggagtt actcctacag
      181 caaacttcac tcaaggcgaa gatgtttttc acgctcctta tgttgctaac caaggatggt
      241 atgatattac caaaacattc aatggaaaag acgatcttct ttgcggggct gccacagcag
      301 ggaatatgct tcactggtgg ttagatcaaa acaacgaaaa aattgaagca tatctaaaaa
      361 aacacccaga taaacaaaaa atcatgtttg gtgatcaaga attattggat gtaagaaaag
      421 ttattaatac taaaggtgac caaacaaata gcgagctttt taattatttc cgagataaag
      481 ctttccccgg tttgtcagca cgccgaattg gagttatgcc tgatcttgtt ttagatatgt
      541 ttatcaatgg ttattactta aatgtttata agacacagac tactgatgtc aatagaacct
      601 atcaagagaa agatcgccga ggtggtattt ttgacgccgt atttacaaga ggtgatcaaa
      661 gtaagctatt gacaagtcgt catgatttta aagaaaaaaa tctcaaagaa atcagtgatc
      721 tcattaagaa agagttaacc gaaggcaagg ctctaggcct atcacacacc tacgctaacg
      781 tacgcatcaa ccatgttata aacctgtggg gagctgactt cgattctaac gggaacctta
      841 aagctattta tgtaacagac tctgatagta atgcatctat tggtatgaag aaatactttg
      901 ttggtgttaa ttccgctgga aaagtagcta tttctgctaa agaaataaaa gaagataata
      961 ttggtgctca agtactaggg ttatttacac tttcaacagg gcaagatagt tggaatcaga
     1021 ccaattaaag cgtatcaata agaaagaata tcttcaacag atgatggtat tctaaggact
     1081 aatactattg cagggaattt ttttatagat gggcaacagc aaaaaacatt aataaatcct
     1141 ata
//
LOCUS       DAUGOH010000088         1066 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUGOH010000088 DAUGOH010000000
VERSION     DAUGOH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.088"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..517
                     /locus_tag="VH957_001675"
     CDS             <1..517
                     /locus_tag="VH957_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEQ8559557.1"
                     /translation="EGYFNSLISYTRMLSEDRSVKLILVEELLSELHFEVDDLLNINN
                     IEFSICNRLIITSFYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGEQIHFEI
                     WNNGERFSDSTLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLNNPARGG
                     ASAIISIKKKI"
     gene            674..814
                     /locus_tag="VH957_001676"
     CDS             674..814
                     /locus_tag="VH957_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEQ8559558.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     VK"
BASE COUNT          373 a          140 c          190 g          363 t
ORIGIN      
        1 tgaaggctat ttcaattctt taatatctta tacacgcatg ctttcagagg atagatcagt
       61 gaaactaatt ttagttgagg agctattaag tgagttacat tttgaagtcg atgacttatt
      121 gaatatcaat aatattgaat tttctatttg taatagactt attatcactt ctttttatgg
      181 agatgaggaa aatctgataa gagctctttc taacctttta gttaatgcaa taagatttat
      241 gcccgtatta gataaaaaaa tcgaagttat actgtctgag tcaggagagc aaattcattt
      301 tgaaatatgg aataatggtg agcgtttcag tgatagtaca ctgaaaaagg gagataaatt
      361 attttacacg gaagattata gcagaggtaa caaacattat ggaatcggtt tggcatttgt
      421 taaaggcgtt gctatcaaac acggtgggaa tcttcaattg aataatccag ctagaggagg
      481 tgctagcgcc ataatctcga taaaaaagaa aatttaatag atttgattga aactggagta
      541 tttcaggcaa aaaatcgtaa atttttgtga tttttggcta aaatactttt tttctgaaca
      601 aattctgaac ttggggtgtc ataataatca tgtaaatata tcggatgcaa aaacgtaaga
      661 gaggaactag aaaatgaata acacaattaa agactttgat ctcgatttga aaacaaataa
      721 aaaagacact gctacacctt atgttggtag ccgttaccta tgtacccctg gttcttgttg
      781 gaaattagtt tgctttacaa caactgttaa ataataaagt tatcattatc atcaacatta
      841 taatttcaaa taatttgata tatttataaa tttaggggag tagactgatt ttagtttgct
      901 cctttattag tagataagga agttatacat gattaaagct cagctaaaga atctaataaa
      961 aacaattcat ctcgtaaaag aggctggttt ctccctactg gtgttctcaa ttgctattag
     1021 cttatttcaa gggattttac ccatttttag tatgctacta gttcaa
//
LOCUS       DAUGOH010000089          949 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUGOH010000089 DAUGOH010000000
VERSION     DAUGOH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.089"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            26..640
                     /locus_tag="VH957_001677"
     CDS             26..640
                     /locus_tag="VH957_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEQ8559559.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
BASE COUNT          329 a          156 c          191 g          273 t
ORIGIN      
        1 acggagaaaa gtgaggtatt attgaatgtt taagaaagaa aatttaaaac aacgttattt
       61 taattttgga ttagtagcgt tagctctaac aatattagcc atcatttttg ccttctcaag
      121 taaaaatgct gatactaagt cttatgctaa gaagtcagaa agtaaaatgg taacaatcga
      181 caaggctcca aaaaataatc atgctattac taaagaagaa agcaaagaaa aagcaaagag
      241 cattgcttcg gagcctattc ccacagtaga aaactctgta gctccgacag taacagagga
      301 agcaccggtt gttcagcaag aagtgactca aactgttcag caggtatctt cagtagccta
      361 taatccaaac aatgtggtac tttccaatgg aaatactgct ggtattgtag gaagtcaagc
      421 ggcggcacag atggcagcag caacaggtgt tccacaatca acttgggaac atataattgc
      481 gcgtgaatct aatggaaatc ctaacgcagc taatgcttct ggggcatcag ggttgttcca
      541 gacaatgcca ggttggggtt ctacagcaac ggttgaagat caagtcaatg cagccttgaa
      601 agcctatagt gcacaaggtt tatcagcttg gggttactaa ataaacatag ctggaagaaa
      661 taaaacctat tgttagtatt tactaacaat aggtttttgg tatttaattg tctttatgat
      721 ttgtagtgat gaattagtct caaaacaaaa cattgcctta tcagggaata tagctcgtat
      781 tatttaggaa aactgaccag cacttaagtg cctctgatat ttaaggcagt tatactgata
      841 acaagcagga aaaaaacttt taaatgttta taaggtcatt agcaattttc agtattttac
      901 actactacac ttttgagttt taacaattta ctaggagttg tttctaagg
//
LOCUS       DAUGOH010000090          851 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUGOH010000090 DAUGOH010000000
VERSION     DAUGOH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.090"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(1..851)
                     /locus_tag="VH957_001678"
                     /pseudo
     CDS             complement(1..851)
                     /locus_tag="VH957_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418808.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          284 a          169 c           91 g          307 t
ORIGIN      
        1 ctccaatttc tttatctaat aagtttttaa acttcattcc tttaatattt aaatcagcga
       61 aacttcctgt ttcagatata catccattat ctagatacaa aattttattc acagattgag
      121 taatgcttgg cttatgcgta ataaaaatac caattttatt ttgcgataat tcaaaaaatg
      181 ttttaaaaat ttttgtttca gactcaggat ctaacgcaga actaggctca tctagcaaat
      241 agcaatccgc ttctttgaga tatactcttg ataatgcaat tttttgccac tgtccaccag
      301 ataactgtct cccatcctca aaccaattcc ctaattgctg ttccagatct atctgattta
      361 atttttcctg attaaagtaa aatatcgaat caactcctgt atacttcagt gcacttatta
      421 aatcctcatc actatataac tttgataatt cacccaatcc aacattttca cgcagtgtca
      481 attcatactt taaaaaatct tggaacaatg cggatattct cttgtagtat gactttttct
      541 gtattgaacg aatattaata ccatttatat atatatattg ccttcataat tatcgtaaag
      601 accgcaggct aatttgaaaa tcgtactttt tccagaacca ttttcacaaa caattgctaa
      661 cctctctcct gctttaattg aaaaacttat atcgtttatt acattatcct taccattata
      721 tgaaaaagaa actctttcaa attcaactga ctgaattgta tcaaccgtac tttcgattat
      781 agggttatgt actaactcat catgcgtaaa atcatacaat aactccatgt acaatgaacc
      841 attatagaaa g
//
LOCUS       DAUGOH010000091          819 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUGOH010000091 DAUGOH010000000
VERSION     DAUGOH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.091"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..719)
                     /locus_tag="VH957_001679"
     rRNA            complement(<1..719)
                     /locus_tag="VH957_001679"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          166 a          250 c          158 g          245 t
ORIGIN      
        1 ctccatatat ctacgcattt caccgctaca catggaattc cactctcccc ttctgcactc
       61 aagttctcca gtttccaaag cgtacattgg ttgagccaat gcctttaact tcagacttaa
      121 aaaaccgcct gcgctcgctt tacgcccaat aaatccggac aacgctcggg acctacgtat
      181 taccgcggct gctggcacgt agttagccgt ccctttctgg ttagttaccg tcacttggtg
      241 gattttccac tcccaccatc attcttctct aacaacagag ctttacgatc cgaaaacctt
      301 cttcactcac gcggcgttgc tcggtcaggg ttgcccccat tgccgaagat tccctactgc
      361 tgcctcccgt aggagtctgg gccgtgtctc agtcccagtg tggccgatca ccctctcagg
      421 tcggctatgt atcgtcgcct tggtgagcct ttacctcacc aactagctaa tacaacgcag
      481 gtccatctca tagtggagca attgcccctt ttaaattact aacatgcgtt agtctctctt
      541 atgcggtatt agctatcgtt tccaatagtt atcccccgct atgaggtagg ttacctacgc
      601 gttactcacc cgttcgcaac tccttgaacc ggtgcaagca ccagttctca gcgttctact
      661 tgcatgtatt aggcacgccg ccagcgttcg tcctgagcca ggatcaaact ctctttaatt
      721 tgcgtttgaa cttactcgtt ccttctgtcg ctgacagatt tatttctcgt ttcttgacgg
      781 gtaatatgtc tccatatcac cctcacgttt ggttcgtct
//
LOCUS       DAUGOH010000092          801 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUGOH010000092 DAUGOH010000000
VERSION     DAUGOH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..801
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.092"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            236..468
                     /locus_tag="VH957_001680"
                     /pseudo
     CDS             236..468
                     /locus_tag="VH957_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
     gene            483..665
                     /locus_tag="VH957_001681"
     CDS             483..665
                     /locus_tag="VH957_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8559560.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
BASE COUNT          259 a           82 c          174 g          286 t
ORIGIN      
        1 aaaggattcg gagtatattt tgacacactt gatagcttat ttgactaata ttcaaaaact
       61 ctactcttgt gtttacacaa cattattgac agtctctaat atgttaaaaa gtttatttga
      121 gatgtttata caaccattca cgacatagaa aaaaattttt ataataatat gctatattta
      181 gtttgtcaaa gttgcaacaa gatgaatata acattttaga aaggttttta aagttatgat
      241 aaaatttgca gaagaaatac aaaaagaaga gttgttccat attattggag gttatagtgc
      301 tacagattgt aaaaatcatt taattggtgg tattacttca ggtgctattg caggtggttg
      361 gctactttag gtgttggagg agttgcaggt gcgtttgcag gtgcacatgt aggtgctatt
      421 gcgggtggat taacttgcgt tggtggtatg ttatttaatg gaaaataatt ttgaggtgaa
      481 aaatggataa ttttttagaa ttacagtttg aagaattagt aaatatttct ggtggaaaag
      541 gaaatattgg atctgctatc ggagggtgct taggtgggat gcttatagct gcagcaggag
      601 gtccaataac tggaggtgcg gcagcatttg tatgtgtagc atctggaatt gcagcttatc
      661 aatgatatga ttatagttat aatactcggt ttaatttgtc taatactttc ccaaattttt
      721 ttgaaggata aagaggtaag agaaaatgca agtaaagtaa ttttaattgt gatatttgtt
      781 tatgtcttac taagtactat t
//
LOCUS       DAUGOH010000093          796 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUGOH010000093 DAUGOH010000000
VERSION     DAUGOH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.093"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..>796
                     /locus_tag="VH957_001682"
     CDS             <1..>796
                     /locus_tag="VH957_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8559561.1"
                     /translation="DIPDEYVHYSRTVYISEGDINLTNNNKKLRISKDVDKLIKQSGK
                     TFITSNLKATKHSTREYSYPYIKGTNAYYSFSYIPQALGILVGNALDLPILLTYYFGR
                     LCNLISYAMLAFIAIKLSGSFKQVIAVVTLLPMNIYLAASFNQDGFAIGLVLVTIGLF
                     INLLSSKDKSNYNTKFFLYLVLCGLLVLSKFTYFLLVCLPLFIPNEKFGKNTKLVILK
                     KLGGLLLIFLFAAMWFRLYGQVKTPYVADFLKEVNVSQQVKNMLESP"
BASE COUNT          266 a          128 c          118 g          284 t
ORIGIN      
        1 gatattcctg atgaatatgt tcattattca aggacagttt atatctcaga aggtgatatt
       61 aatcttacca acaataacaa aaagttaaga atatccaaag atgttgataa gcttattaaa
      121 cagtcaggaa aaacatttat aacatcaaac ttgaaagcaa ctaaacacag cacaagagag
      181 tatagctatc cttacatcaa aggaactaat gcatattata gtttttctta tataccacaa
      241 gctttgggta ttttagtagg aaatgcgctg gatttaccta tacttttaac atattatttc
      301 ggaagattgt gcaaccttat tagctacgct atgcttgctt ttatagctat caagttgtct
      361 ggttctttta aacaagtgat agctgttgtt actttactac ctatgaacat ttatttagca
      421 gcatctttta atcaagacgg ctttgctatc ggtttagttt tagtaacaat tggattgttt
      481 attaacttgc tctcatcaaa agataaatct aactataata ccaaattctt cctttattta
      541 gttctatgtg ggttactagt tctttcaaaa ttcacatact ttttattagt atgccttcca
      601 ttatttattc ctaatgaaaa attcggaaaa aataccaagt tagtcatctt gaaaaaattg
      661 ggaggactat tactcatttt tctttttgct gcaatgtggt ttagacttta tggacaggtt
      721 aaaaccccat atgtcgcgga ttttctaaaa gaagtaaacg ttagccagca agttaaaaat
      781 atgctagaat ccccta
//
LOCUS       DAUGOH010000094          784 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUGOH010000094 DAUGOH010000000
VERSION     DAUGOH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.094"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            55..>784
                     /gene="mf2"
                     /locus_tag="VH957_001683"
     CDS             55..>784
                     /gene="mf2"
                     /locus_tag="VH957_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNase Mf2"
                     /protein_id="HEQ8559562.1"
                     /translation="MKLSKQKASLLTAVLLLLSLSITTITVDAARVRTYPNVSHANTH
                     YKNTVSSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHETKDVRTKINYDPVGWHN
                     YQFPYGDGSKSSWVMNRGHLVGYQFCGLNDEPRNLVAMTAWLNTGAYSGANDSNPEGM
                     LYYENRLDSWLALHPDFWLDYKVTPIYSGNEVVPRQIELQYVGIDSSGELLTIRLNSN
                     KESIDENGVTTVILENSAPNINLDY"
BASE COUNT          259 a          143 c          144 g          238 t
ORIGIN      
        1 gtgcaatatt tgatccactc taaaagctaa aaatggaaag gtttaggtgt tatcatgaaa
       61 ttatctaaac aaaaggcaag tttgcttacc gctgttttac tgttactttc tctttctata
      121 acgacaataa ctgttgacgc agctagggta cgaacttatc cgaatgtatc ccatgcaaac
      181 acacattata aaaatactgt ttctagtaag ctcttacctt ttactgctaa ttatcagtta
      241 caacttggtg agttggataa ccttaaccgc gctacctttt cacatatcca actgcaagat
      301 agacacgaaa ctaaagatgt acgcactaaa ataaattatg accctgtggg atggcacaac
      361 tatcaatttc catacggaga tggctcaaaa tcttcatggg taatgaatcg tgggcatcta
      421 gtcggatatc aattttgtgg attaaacgat gaaccaagaa atttagtggc aatgacagcc
      481 tggctaaaca caggtgctta ttcaggagca aatgacagca atcctgaagg gatgttatac
      541 tatgaaaacc gtttagattc ttggcttgca cttcaccctg acttttggct agattataaa
      601 gtcactccta tatatagtgg caatgaagta gtgcctcgac aaattgaatt acagtatgtt
      661 ggaattgatt catctggtga gttgcttact ataaggctaa atagtaataa agaaagtatt
      721 gatgaaaatg gtgttactac agtaatctta gaaaactctg ctccaaatat caaccttgac
      781 tatt
//
LOCUS       DAUGOH010000095          703 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUGOH010000095 DAUGOH010000000
VERSION     DAUGOH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.095"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            20..>703
                     /locus_tag="VH957_001684"
     CDS             20..>703
                     /locus_tag="VH957_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8559563.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVMVVRNDLEYSI
                     RINFPLISKF"
BASE COUNT          252 a           88 c          126 g          237 t
ORIGIN      
        1 ttatttatga ggtgtaacta tggatttaaa aattacaaac ggcttttatg acccaagtca
       61 tttatcatac gaagtagtag aacgcaaagg cttaggtcac cctgatacct tagcagatgg
      121 aattgctgag caaattgaaa ttgattactc actttattgt ttggacaagt ttggtgttat
      181 tccacatcat aattttgata agattattat ccgaggggga cattcagttc aggattttgg
      241 tggaagtgac tttattgaac caattaaaat tatttttcta ggtagggcga gcaaaaaatg
      301 ttttaatagt tcaattccac tttttaaaat tcagaaaaag gctgcaacta aatatttaaa
      361 tagaatttta cctaatttag atgttgaaaa ttatgtagaa tttgagacat tgacctcaga
      421 ttttactaca aaaactaatt ggttctcgcc tgaagcaata gaagatttac cggagtatct
      481 agatgtacca aaggcaaatg atacagctac aatgataagt tattggccat taacaatttc
      541 tgaagaatta gcattaatga ttgaagggta tttttataaa ttagataaga atgaattacc
      601 aacgccaaga tttactaaaa tgggtggtga tattaaagta atggtcgtaa ggaacgattt
      661 agaatattct attagaataa attttccttt aataagtaaa ttt
//
LOCUS       DAUGOH010000096          667 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUGOH010000096 DAUGOH010000000
VERSION     DAUGOH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..667
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.096"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            6..>667
                     /locus_tag="VH957_001685"
     CDS             6..>667
                     /locus_tag="VH957_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003649446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8559564.1"
                     /translation="MQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIMKIL
                     TGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVSEST
                     ILPLLNKVGLGDIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIGIQE
                     LREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIVLEKEYDGSENLEELFNN
                     QI"
BASE COUNT          248 a           86 c          127 g          206 t
ORIGIN      
        1 tgaaaataca aaatctaaaa aaatcttatg gtaagagaac catattgaat aatgtcaata
       61 tgaatattcc taagggaaaa gtgtatgctt taatcggtcc aaatggtgct ggaaaatcaa
      121 ctattatgaa aattttgaca ggcttagtta gtaagacaag tggttctatt atttttgaag
      181 gtagagaatg gtcacgtcgg gatctgcgaa aaatcgggag tattattgaa gaaccaccac
      241 tttataaaaa tttgagtgct tacgataata tgaaggtagt tacaacaatg cttggtgttt
      301 cagaaagcac tatacttcca ttattaaata aagttggtct aggagatatt gacaagagac
      361 cagtaaaaca attttctctt ggaatgaagc aacggttagg tatagctatc tctttaataa
      421 attcacctaa actacttata ttagacgaac ctactaatgg cttggaccca attggaattc
      481 aagaattaag ggaaattata gagtcattta aatcagaagg aatgacaatt atgatttcaa
      541 gccatatact gtcagaagtt gaacatctag ctgattttat tggatttatc tatgaaggaa
      601 agattgttct ggaaaaagaa tatgacggct ctgagaatct tgaagagtta ttcaataatc
      661 aaatttt
//
LOCUS       DAUGOH010000097          536 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUGOH010000097 DAUGOH010000000
VERSION     DAUGOH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.097"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..>536)
                     /locus_tag="VH957_001686"
     CDS             complement(<1..>536)
                     /locus_tag="VH957_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8559565.1"
                     /translation="KRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPEG
                     KLYLLPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKTFPADSYSGTILHSDQGWQYQHQ
                     SYHDFLESKGILPSTSRKGNSPDNGMMDSFFGILKSEMFYGLETTYQSLDKLEEAITD
                     YIFYYNNKRIKAKLKGFS"
BASE COUNT          153 a          105 c          109 g          169 t
ORIGIN      
        1 actaaatcct tttagttttg ctttaattcg tttgttgttg tagtaaaaaa tgtaatctgt
       61 aatagcttct tcaagcttat caagtgattg ataagttgtc tcgagtccat aaaacatttc
      121 agatttgaga atgccaaaga aggaatccat catgccgtta tccgggctat tccctttgcg
      181 ggacgtggat ggcagaatac ctttagactc taaaaaatca tggtaggact ggtgttggta
      241 ttgccacccc tggtcactat gaagaatagt tccgctgtat gaatccgctg gaaaagtctt
      301 ctcaagcatg gtttgaacct gtttcaagtt aggagaccga gacagagtga aatcaataat
      361 ctcactgtta tagccgtcaa gaacaggtaa taagtagagt tttccttcag gtaaggccaa
      421 ctccgtcaca tcagtgtaac atttttcgta aggtttagag ccttcgaagt gacgtttaat
      481 cagattatca gccttcttac caacctctcc tttgtaagaa gaatacttgc gcttcc
//
LOCUS       DAUGOH010000098          535 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUGOH010000098 DAUGOH010000000
VERSION     DAUGOH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.098"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(<1..>535)
                     /locus_tag="VH957_001687"
     CDS             complement(<1..>535)
                     /locus_tag="VH957_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ8559566.1"
                     /translation="LMTTLGEVALGSQTIFNILFMPAFVMNLLILFFRPYITQMAIAL
                     IRGQIKEFNKIQVQLFAYLGVFSLIALVGSGLFGIPFLSMLYGTNLTDYWVDFMLIML
                     GGSIGSFATVIDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSFLIT
                     MLVWLGLSIMIYLFIMN"
BASE COUNT          223 a           97 c           68 g          147 t
ORIGIN      
        1 ctattcataa taaatagata aatcataatg gataatccca accaaaccaa cattgttatt
       61 aaaaagctca aagcagctcc taaaatgtga tatttcataa caaaaagatt ggtaattaat
      121 aacgaaatca aaaatcctcc tgtatatgga ataagaagaa gttgctgttt tctcatagcg
      181 gttaagatat tatcgataac tgtcgcaaaa ctaccaatcg agcctcctag cataatcaac
      241 ataaagtcta cccaataatc cgtaaggtta gtaccatata gcattgataa aaagggaata
      301 ccaaacaaac cacttccaac taacgctatc agtgaaaaaa ctcctaaata agcaaacaat
      361 tgaacttgta tcttattaaa ctcttttatt tgacctctga ttaaagcaat agccatctgt
      421 gtaatataag gtctaaaaaa taaaattagc aaattcataa caaaggctgg cataaataaa
      481 atattaaaaa ttgtttgaga gcccaaagca acttcaccta aagtcgtcat tagtt
//
LOCUS       DAUGOH010000099          535 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUGOH010000099 DAUGOH010000000
VERSION     DAUGOH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.099"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(79..151)
                     /locus_tag="VH957_001688"
     tRNA            complement(79..151)
                     /locus_tag="VH957_001688"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(116..118),aa:Phe,seq:gaa)
     gene            complement(172..245)
                     /locus_tag="VH957_001689"
     tRNA            complement(172..245)
                     /locus_tag="VH957_001689"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(209..211),aa:Met,seq:cat)
     gene            complement(255..344)
                     /locus_tag="VH957_001690"
     tRNA            complement(255..344)
                     /locus_tag="VH957_001690"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(306..308),aa:Ser,seq:tga)
     gene            complement(367..440)
                     /locus_tag="VH957_001691"
     tRNA            complement(367..440)
                     /locus_tag="VH957_001691"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(404..406),aa:Ile,seq:cat)
     gene            complement(461..534)
                     /locus_tag="VH957_001692"
     tRNA            complement(461..534)
                     /locus_tag="VH957_001692"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(498..500),aa:Met,seq:cat)
BASE COUNT          149 a          149 c          124 g          113 t
ORIGIN      
        1 gtgacgagaa tcgaactcgc gacaacagct tggaaggctg tagttttacc actaaactac
       61 acccgcaata tgataacatg gcgcgagacg gaatcgaacc gccgacacat ggagcttcaa
      121 tccattgctc taccaactga gctaccgagc caacaactac atacttatgt attgcgggag
      181 caggatttga acctacgacc ttcgggttat gagcccgacg agctacctaa ctgctccatc
      241 ccgcgatagt taaaaggagg atgtgggatt cgaacccacg cacgctttta cacgcctgac
      301 ggttttcaag accgttccct tcagccggac ttgggtaatc ctccaaaata atgattatct
      361 atgatatgga ccttgtagga ctcgaaccta cgaccgctcg gttatgagcc gagtgctcta
      421 accagttgag ctaaaggtcc caagtcatcc ataaaaataa tagcggcgaa ggggatcgaa
      481 cccccgacct cccgggtatg aaccggacgc tctagccagc tgagctacac cgcca
//
LOCUS       DAUGOH010000100          523 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUGOH010000100 DAUGOH010000000
VERSION     DAUGOH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.100"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..>523
                     /locus_tag="VH957_001693"
     CDS             <1..>523
                     /locus_tag="VH957_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEQ8559567.1"
                     /translation="ISVSNILKINKKATIVIKSTVPIGFTEYLRNQFHYNDIIFSPEF
                     LREGSTIHDQLYPSRTIVGNESRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFS
                     NAYLAQKIAFFNELDTFAEMQNLDSKKIIEAMGYDQRIGNSHNNPSFGFGGYCLPKDI
                     KQLEYHFKEIPAPI"
BASE COUNT          183 a           78 c           89 g          173 t
ORIGIN      
        1 aatttctgta agtaatattt taaagataaa caaaaaggct acaattgtaa taaagtcgac
       61 agttccaatt ggttttacag aatatttaag gaatcaattt cactacaacg atatcatttt
      121 ttcacctgag ttccttaggg aaggatcaac tattcatgat caattgtatc cttcgagaac
      181 tatagttgga aatgaatcta gaaattctca attattctta gacatactaa cagatatatc
      241 ggttgaaaaa gactcgccat ctttattagt tggctcttct gaagcagaag cgataaagtt
      301 attttcgaat gcatacttgg cacaaaaaat tgcttttttt aatgagttgg atacgtttgc
      361 tgaaatgcaa aatttggact caaaaaaaat tattgaggct atgggatatg accagagaat
      421 aggaaattcg cacaataatc cttctttcgg ttttggtggg tactgtcttc ctaaggatat
      481 taagcaatta gagtatcatt ttaaagaaat tccagcacca att
//
LOCUS       DAUGOH010000101          522 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUGOH010000101 DAUGOH010000000
VERSION     DAUGOH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.101"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            complement(70..142)
                     /locus_tag="VH957_001694"
     tRNA            complement(70..142)
                     /locus_tag="VH957_001694"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(107..109),aa:Thr,seq:tgt)
     gene            complement(153..234)
                     /locus_tag="VH957_001695"
     tRNA            complement(153..234)
                     /locus_tag="VH957_001695"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(198..200),aa:Leu,seq:tag)
     gene            complement(240..312)
                     /locus_tag="VH957_001696"
     tRNA            complement(240..312)
                     /locus_tag="VH957_001696"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(277..279),aa:Lys,seq:ttt)
     gene            complement(344..416)
                     /locus_tag="VH957_001697"
     tRNA            complement(344..416)
                     /locus_tag="VH957_001697"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Asp,seq:gtc)
     gene            complement(434..506)
                     /locus_tag="VH957_001698"
     tRNA            complement(434..506)
                     /locus_tag="VH957_001698"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(471..473),aa:Val,seq:tac)
BASE COUNT          133 a          153 c          110 g          126 t
ORIGIN      
        1 tcgaacccgc gacccccacc ttggcaaggt gatgttctac cactgaacta cgttcgcaac
       61 taatctcaat gccggctaca tgacttgaac acgcgaccct ctgattacaa atcagatgct
      121 ctaccaactg agctaagccg gctaatcttt tatgcgggtt aagggacttg aacccccacg
      181 ccgttaagcg ccagatccta aatctggtgc gtctgccaat tccgccaaac ccgcttttat
      241 gacccgtact gggctcgaac cagtgaccca ttgattaaaa gtcaattgct ctaccaactg
      301 agctaacgag tctttccttc aaaaaatatg actactcttt gaacggtccc gacgggaatc
      361 gaacccgcga tcttcgccgt gacagggcga cgtgataacc gctacactac gggacctgta
      421 ttttccaata ctatgggagt taacgggatc gaaccgctga ccctctgctt gtaaggcaga
      481 tgctctccca gctgagctaa actcccattg agtgtgtcat ta
//
LOCUS       DAUGOH010000102          502 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUGOH010000102 DAUGOH010000000
VERSION     DAUGOH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.102"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            <1..474
                     /locus_tag="VH957_001699"
     CDS             <1..474
                     /locus_tag="VH957_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEQ8559568.1"
                     /translation="IYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLIDLNFID
                     DINESLIAQMRSSDKNVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQIIT
                     SFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVLFLLNPYSDEELLWQRIFI"
BASE COUNT          170 a           61 c          104 g          167 t
ORIGIN      
        1 atttatacta gtaatatttt ggatcttgat ttaaattatc ttcctactag aatggcatgg
       61 tgttacggta cgcctggaac tgcagttgcc ctttttaaaa tgtgtcaatt gatagattta
      121 aattttattg acgatattaa tgaaagttta attgctcaga tgagaagttc agacaaaaat
      181 gtctattctc ttacaatgtg ccatggtttg gcaggagtaa cttttatata tgacttgatt
      241 ggtaaaaatt attcaagtga gaggctaact cgctttgcag aagagcttcg ccaacaaata
      301 attacatcgt tttcaactac aaaagtattt gggtatactg acagagaaaa atttggagaa
      361 atagaagttg aactggagtc aatagggata ttgcaagggg tatcagggat agtgttattc
      421 ttattaaatc cttacagtga cgaggagcta ttgtggcaaa gaatatttat ttaatttgaa
      481 aaggagaaca aaatgtataa gg
//
LOCUS       DAUGOH010000103          467 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUGOH010000103 DAUGOH010000000
VERSION     DAUGOH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.103"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
BASE COUNT          154 a           50 c           93 g          170 t
ORIGIN      
        1 tttttgatac tttgagtagt aacgataata tttaattttt tgatggatta ctttaattga
       61 ctttagtggg ttagatgcca gtttggattt ttgatatttg tgttgagttt aaaagataaa
      121 aacacttaat gaaaatctgt tttttcttag aaaggggacc agtatgattg agacgctaat
      181 gagtacgttg gaaatggtta gaaaaaaaat cctagtagga ctgcaatcga agatgacttt
      241 gaggaatata aaaagagaaa tctaccaatc tttgtcagtg aagatgatag tgtgatctat
      301 tatagactag ggttcatttt taatgaattc tatcccaata tttcaggctg gagacaagaa
      361 ctaaagacta agcttactag tatttcttta atttctttac attttattgg tgttgttgac
      421 gaacaaaaaa agggggaata tctaggttct ttttctgata catctga
//
LOCUS       DAUGOH010000104          435 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00043699
            SAMN33608713-rid17958023.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUGOH010000104 DAUGOH010000000
VERSION     DAUGOH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608713
            Sequence Read Archive: SRR23751668
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723416.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723416.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:26:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,700
            CDSs (total)                      :: 1,663
            Genes (coding)                    :: 1,614
            CDSs (with protein)               :: 1,614
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 31 of 49
            Pseudo Genes (incomplete)         :: 16 of 49
            Pseudo Genes (internal stop)      :: 15 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608713-rid17958023.denovo.104"
                     /strain="AUSMDU00043699"
                     /serotype="EMM89.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST101"
     gene            118..342
                     /locus_tag="VH957_001700"
     CDS             118..342
                     /locus_tag="VH957_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8559569.1"
                     /translation="MTYFRLKKELNWSLRDKGMVVYEGNQKLQIAINTGKNNSEKVFF
                     DTFFEVVRAAATFSTAKNICFGLGLLRSQK"
BASE COUNT          144 a           57 c           87 g          147 t
ORIGIN      
        1 caataaacaa ataggagggc aattgtttaa ctggttaatt agaatttttg ttattttcag
       61 gaagatactc agggcttttt tataagttga tgtattaaca aaagataaaa aggtttcatg
      121 acttatttta gattaaaaaa agaattaaac tggtcactaa gagataaagg aatggtagtt
      181 tatgaaggga atcaaaaact tcagatagcc attaatacag gtaaaaataa cagtgaaaaa
      241 gtcttttttg atactttttt tgaggtggtt cgggcggcag cgactttctc cacagcaaaa
      301 aacatctgtt ttggtcttgg cttacttcgt tcgcagaaat aggaaatcgg gtatcacatt
      361 agcagagtag ttcatgcttt ttgagcatca cattgggtct gtctacgttc taaaagcttt
      421 tgtcattttt gtatc
//
